pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6390-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 25 25 4,000 3,635E-07 6,7E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 3,000 4,229E-07 3,897E-04 GO:0032388|positive regulation of intracellular transport, ! cell cycle arrest GO:0007050 49 49 5,000 4,754E-07 2,92E-04 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 4,000 5,473E-07 2,522E-04 ! response to endoplasmic reticulum stress GO:0034976 13 13 3,000 9,081E-07 3,347E-04 ! regulation of intracellular transport GO:0032386 31 31 4,000 1,131E-06 3,474E-04 ! response to vitamin GO:0033273 15 15 3,000 1,718E-06 4,523E-04 ! ER-nuclear signaling pathway GO:0006984 15 15 3,000 1,718E-06 3,958E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 2,000 4,49E-06 9,195E-04 ! ER overload response GO:0006983 6 6 2,000 4,49E-06 8,275E-04 ! T cell activation GO:0042110 51 50 4,000 1,292E-05 2,164E-03 ! regulation of protein transport GO:0051223 53 53 4,000 1,726E-05 2,65E-03 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 1,861E-05 2,639E-03 ! regulation of protein localization GO:0032880 58 57 4,000 2,472E-05 3,254E-03 ! positive regulation of protein transport GO:0051222 29 29 3,000 2,805E-05 3,446E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 6,018E-05 6,932E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 6,228E-05 6,751E-03 ! response to nutrient levels GO:0031667 69 69 4,000 6,277E-05 6,427E-03 ! regulation of cell migration GO:0030334 71 71 4,000 7,205E-05 6,989E-03 ! response to extracellular stimulus GO:0009991 72 72 4,000 7,707E-05 7,102E-03 ! response to retinoic acid GO:0032526 14 14 2,000 7,892E-05 6,926E-03 GO:0033189|response to vitamin A, ! cell-matrix adhesion GO:0007160 39 38 3,000 8,369E-05 7,011E-03 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 9,821E-05 7,87E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 9,821E-05 7,542E-03 ! regulation of locomotion GO:0040012 79 79 4,000 1,202E-04 8,861E-03 ! regulation of cell motion GO:0051270 79 79 4,000 1,202E-04 8,521E-03 ! cell-substrate adhesion GO:0031589 43 42 3,000 1,246E-04 8,506E-03 ! lymphocyte activation GO:0046649 82 81 4,000 1,354E-04 8,912E-03 ! negative regulation of cell development GO:0010721 18 17 2,000 1,455E-04 9,247E-03 GO:0050768|negative regulation of neurogenesis, ! regulation of cellular localization GO:0060341 86 85 4,000 1,702E-04 0,01045421 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 1,798E-04 0,01069207 ! DNA damage checkpoint GO:0000077 19 19 2,000 2,055E-04 0,01183822 ! response to nutrient GO:0007584 49 49 3,000 2,285E-04 0,01276271 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 2,671E-04 0,01447857 GO:0051325|interphase, ! DNA integrity checkpoint GO:0031570 21 21 2,000 2,797E-04 0,01472685 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 2,797E-04 0,01431777 ! negative regulation of protein transport GO:0051224 21 21 2,000 2,797E-04 0,01393081 ! mRNA stabilization GO:0048255 5 5 1,000 3,771E-04 0,01828773 GO:0043489|RNA stabilization, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 3,771E-04 0,01781881 ! response to interferon-gamma GO:0034341 5 5 1,000 3,771E-04 0,01737334 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 3,771E-04 0,0169496 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! receptor clustering GO:0043113 5 5 1,000 3,771E-04 0,01654604 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 3,771E-04 0,01616125 ! neuron recognition GO:0008038 5 5 1,000 3,771E-04 0,01579395 ! T cell lineage commitment GO:0002360 5 5 1,000 3,771E-04 0,01544297 ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,771E-04 0,01510725 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 3,771E-04 0,01478582 ! positive regulation of T-helper cell differentiation GO:0045624 5 5 1,000 3,771E-04 0,01447778 GO:0045622|regulation of T-helper cell differentiation, ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 1,000 3,771E-04 0,01418232 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 3,771E-04 0,01389867 ! T cell differentiation GO:0030217 24 24 2,000 4,201E-04 0,01518064 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 4,201E-04 0,01488871 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 4,691E-04 0,01631375 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 5,634E-04 0,01922709 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of positive chemotaxis GO:0050926 6 6 1,000 5,634E-04 0,01887751 GO:0050927|positive regulation of positive chemotaxis, ! oligodendrocyte differentiation GO:0048709 6 6 1,000 5,634E-04 0,01854041 ! regulation of vascular permeability GO:0043114 6 6 1,000 5,634E-04 0,01821514 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 5,634E-04 0,01790108 ! regulation of bone resorption GO:0045124 6 6 1,000 5,634E-04 0,01759768 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 5,634E-04 0,01730438 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 5,634E-04 0,0170207 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 1,000 5,634E-04 0,01674617 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! negative regulation of cell projection organization GO:0031345 8 7 1,000 7,856E-04 0,02298096 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 7,856E-04 0,02262188 ! response to X-ray GO:0010165 7 7 1,000 7,856E-04 0,02227385 ! regulation of intracellular pH GO:0051453 7 7 1,000 7,856E-04 0,02193637 ! response to gamma radiation GO:0010332 8 7 1,000 7,856E-04 0,02160896 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 1,000 7,856E-04 0,02129118 ! regulation of mRNA stability GO:0043488 7 7 1,000 7,856E-04 0,02098262 ! biogenic amine catabolic process GO:0042402 7 7 1,000 7,856E-04 0,02068286 ! regulation of axon extension GO:0030516 7 7 1,000 7,856E-04 0,02039156 ! SMAD protein nuclear translocation GO:0007184 7 7 1,000 7,856E-04 0,02010834 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 1,000 7,856E-04 0,01983288 ! regulation of mRNA processing GO:0050684 7 7 1,000 7,856E-04 0,01956487 ! axon cargo transport GO:0008088 7 7 1,000 7,856E-04 0,01930401 ! cranial nerve development GO:0021545 7 7 1,000 7,856E-04 0,01905001 ! autonomic nervous system development GO:0048483 7 7 1,000 7,856E-04 0,0188026 ! regulation of cell size GO:0008361 68 68 3,000 8,059E-04 0,01904313 ! positive regulation of transport GO:0051050 71 70 3,000 8,992E-04 0,02097806 ! negative regulation of cell growth GO:0030308 32 32 2,000 9,942E-04 0,02290443 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,043E-03 0,02373758 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,043E-03 0,0234481 ! NAD metabolic process GO:0019674 8 8 1,000 1,043E-03 0,02316559 ! plasma membrane fusion GO:0045026 8 8 1,000 1,043E-03 0,02288981 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,043E-03 0,02262052 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,043E-03 0,02235749 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,043E-03 0,02210051 ! regulation of RNA stability GO:0043487 8 8 1,000 1,043E-03 0,02184937 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,043E-03 0,02160387 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,043E-03 0,02136382 ! negative regulation of cell size GO:0045792 33 33 2,000 1,089E-03 0,02205322 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,189E-03 0,0238207 ! regulation of protein catabolic process GO:0042176 35 34 2,000 1,189E-03 0,02356456 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 1,295E-03 0,02538894 ! viral genome replication GO:0019079 9 9 1,000 1,336E-03 0,02591893 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,336E-03 0,02564894 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 1,000 1,336E-03 0,02538452 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,336E-03 0,0251255 ! pigmentation during development GO:0048066 9 9 1,000 1,336E-03 0,0248717 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 1,336E-03 0,02462299 ! regulation of cellular pH GO:0030641 9 9 1,000 1,336E-03 0,02437919 ! histone acetylation GO:0016573 9 9 1,000 1,336E-03 0,02414018 ! cellular amino acid derivative catabolic process GO:0042219 10 9 1,000 1,336E-03 0,02390581 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,336E-03 0,02367595 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,336E-03 0,02345046 ! aromatic amino acid family catabolic process GO:0009074 9 9 1,000 1,336E-03 0,02322923 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,336E-03 0,02301214 ! positive regulation of cell migration GO:0030335 36 36 2,000 1,407E-03 0,02400212 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 1,407E-03 0,02378192 ! regulation of transcription factor activity GO:0051090 38 37 2,000 1,524E-03 0,02553385 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 2,000 1,524E-03 0,02530382 ! negative regulation of growth GO:0045926 37 37 2,000 1,524E-03 0,02507789 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 1,524E-03 0,02485596 ! tube development GO:0035295 83 81 3,000 1,552E-03 0,02509857 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 1,647E-03 0,02640219 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 1,663E-03 0,02642823 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,663E-03 0,02620235 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,663E-03 0,0259803 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,663E-03 0,02576198 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,663E-03 0,02554729 ! myoblast differentiation GO:0045445 10 10 1,000 1,663E-03 0,02533616 ! centrosome cycle GO:0007098 10 10 1,000 1,663E-03 0,02512849 ! cellular response to unfolded protein GO:0034620 10 10 1,000 1,663E-03 0,02492419 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 1,663E-03 0,02472319 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 1,663E-03 0,0245254 ! nerve development GO:0021675 10 10 1,000 1,663E-03 0,02433076 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,663E-03 0,02413918 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,663E-03 0,02395059 ! protein stabilization GO:0050821 10 10 1,000 1,663E-03 0,02376492 ! respiratory tube development GO:0030323 40 39 2,000 1,777E-03 0,02519243 ! respiratory system development GO:0060541 40 39 2,000 1,777E-03 0,02500012 ! lymphocyte differentiation GO:0030098 39 39 2,000 1,777E-03 0,02481072 ! protein oligomerization GO:0051259 39 39 2,000 1,777E-03 0,02462418 ! positive regulation of cell motion GO:0051272 39 39 2,000 1,777E-03 0,02444041 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 1,913E-03 0,0261127 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 2,025E-03 0,02744186 ! signal complex assembly GO:0007172 11 11 1,000 2,025E-03 0,02724155 ! microtubule-based transport GO:0010970 11 11 1,000 2,025E-03 0,02704415 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,025E-03 0,02684959 ! dendrite development GO:0016358 11 11 1,000 2,025E-03 0,0266578 ! cellular response to starvation GO:0009267 11 11 1,000 2,025E-03 0,02646874 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,025E-03 0,02628234 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,025E-03 0,02609855 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 2,025E-03 0,02591731 ! intermediate filament-based process GO:0045103 11 11 1,000 2,025E-03 0,02573857 ! regulation of interleukin-2 production GO:0032663 11 11 1,000 2,025E-03 0,02556228 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 2,025E-03 0,02538839 ! hindbrain development GO:0030902 11 11 1,000 2,025E-03 0,02521684 ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 2,025E-03 0,0250476 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,055E-03 0,02524694 ! regulation of caspase activity GO:0043281 41 41 2,000 2,055E-03 0,02507974 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 2,203E-03 0,02671503 ! negative regulation of ligase activity GO:0051352 43 42 2,000 2,203E-03 0,02654042 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 2,000 2,203E-03 0,02636808 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,42E-03 0,0287792 ! xenobiotic metabolic process GO:0006805 12 12 1,000 2,42E-03 0,02859472 ! microtubule organizing center organization GO:0031023 12 12 1,000 2,42E-03 0,02841259 GO:0051297|centrosome organization, ! barbed-end actin filament capping GO:0051016 12 12 1,000 2,42E-03 0,02823276 GO:0051693|actin filament capping, ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 2,42E-03 0,0280552 ! somitogenesis GO:0001756 13 12 1,000 2,42E-03 0,02787985 ! aromatic compound catabolic process GO:0019439 13 12 1,000 2,42E-03 0,02770669 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 2,42E-03 0,02753566 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 2,42E-03 0,02736673 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 2,52E-03 0,02831803 ! protein import into nucleus GO:0006606 44 44 2,000 2,52E-03 0,0281464 ! pattern specification process GO:0007389 96 94 3,000 2,683E-03 0,02979097 ! regulation of DNA binding GO:0051101 47 45 2,000 2,688E-03 0,0296667 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 2,688E-03 0,02949012 ! nuclear import GO:0051170 45 45 2,000 2,688E-03 0,02931562 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 2,688E-03 0,02914317 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,849E-03 0,03070736 ! negative regulation of actin filament polymerization GO:0030837 13 13 1,000 2,849E-03 0,03052883 ! patterning of blood vessels GO:0001569 13 13 1,000 2,849E-03 0,03035236 ! vasculogenesis GO:0001570 13 13 1,000 2,849E-03 0,03017792 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,849E-03 0,03000548 ! negative regulation of DNA replication GO:0008156 13 13 1,000 2,849E-03 0,02983499 ! receptor metabolic process GO:0043112 14 13 1,000 2,849E-03 0,02966643 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 2,849E-03 0,02949977 ! cell aging GO:0007569 13 13 1,000 2,849E-03 0,02933496 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,849E-03 0,02917199 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,849E-03 0,02901082 ! regulation of axonogenesis GO:0050770 14 13 1,000 2,849E-03 0,02885142 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 2,849E-03 0,02869376 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,849E-03 0,02853782 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,849E-03 0,02838356 ! response to cytokine stimulus GO:0034097 13 13 1,000 2,849E-03 0,02823096 ! water-soluble vitamin biosynthetic process GO:0042364 13 13 1,000 2,849E-03 0,02807999 ! tissue homeostasis GO:0001894 13 13 1,000 2,849E-03 0,02793063 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 2,849E-03 0,02778285 ! regulation of peptidase activity GO:0052547 46 46 2,000 2,863E-03 0,02777395 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 2,863E-03 0,02762853 ! positive regulation of ligase activity GO:0051351 47 46 2,000 2,863E-03 0,02748464 ! regulation of catabolic process GO:0009894 48 47 2,000 3,045E-03 0,02908007 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 3,122E-03 0,02965531 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 3,234E-03 0,03056777 ! protein localization in nucleus GO:0034504 48 48 2,000 3,234E-03 0,03041181 ! protein amino acid acylation GO:0043543 14 14 1,000 3,311E-03 0,030974 ! regulation of neuron projection development GO:0010975 15 14 1,000 3,311E-03 0,03081757 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 3,311E-03 0,0306627 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of behavior GO:0050795 14 14 1,000 3,311E-03 0,03050939 ! vitamin biosynthetic process GO:0009110 14 14 1,000 3,311E-03 0,0303576 ! base-excision repair GO:0006284 14 14 1,000 3,311E-03 0,03020732 ! negative regulation of protein polymerization GO:0032272 14 14 1,000 3,311E-03 0,03005851 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 3,358E-03 0,03033855 ! hemopoiesis GO:0030097 104 100 3,000 3,358E-03 0,03019056 ! leukocyte differentiation GO:0002521 50 49 2,000 3,43E-03 0,03068927 ! skeletal muscle tissue development GO:0007519 50 49 2,000 3,43E-03 0,03054101 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 2,000 3,43E-03 0,03039418 ! negative regulation of transport GO:0051051 51 50 2,000 3,633E-03 0,03204035 ! regulation of neurogenesis GO:0050767 51 50 2,000 3,633E-03 0,03188777 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 3,633E-03 0,03173665 ! negative regulation of actin filament depolymerization GO:0030835 15 15 1,000 3,805E-03 0,03307916 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 3,805E-03 0,03292386 ! response to starvation GO:0042594 15 15 1,000 3,805E-03 0,03277001 ! response to ionizing radiation GO:0010212 16 15 1,000 3,805E-03 0,03261759 ! nicotinamide metabolic process GO:0006769 15 15 1,000 3,805E-03 0,03246658 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 3,805E-03 0,03231696 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 1,000 3,805E-03 0,03216872 ! response to hypoxia GO:0001666 53 53 2,000 4,287E-03 0,03607417 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 4,331E-03 0,036286 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 1,000 4,331E-03 0,03612181 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 4,331E-03 0,0359591 ! segmentation GO:0035282 17 16 1,000 4,331E-03 0,03579785 ! cellular response to nutrient levels GO:0031669 16 16 1,000 4,331E-03 0,03563803 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 4,331E-03 0,03547964 ! positive regulation of catabolic process GO:0009896 16 16 1,000 4,331E-03 0,03532265 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 4,331E-03 0,03516705 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 4,331E-03 0,03501281 ! response to oxygen levels GO:0070482 55 54 2,000 4,519E-03 0,03637036 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 4,759E-03 0,0381359 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 4,89E-03 0,03901105 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 4,89E-03 0,0388429 ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 4,89E-03 0,03867619 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 4,89E-03 0,03851091 ! tissue remodeling GO:0048771 17 17 1,000 4,89E-03 0,03834704 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 4,89E-03 0,03818455 ! cell recognition GO:0008037 18 17 1,000 4,89E-03 0,03802343 ! pyridine nucleotide metabolic process GO:0019362 17 17 1,000 4,89E-03 0,03786367 ! pigmentation GO:0043473 17 17 1,000 4,89E-03 0,03770524 ! regulation of nervous system development GO:0051960 57 56 2,000 5,007E-03 0,03844878 ! regulation of binding GO:0051098 60 57 2,000 5,262E-03 0,04024186 ! regulation of cell projection organization GO:0031344 19 18 1,000 5,479E-03 0,04172705 ! meiosis I GO:0007127 18 18 1,000 5,479E-03 0,04155534 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 5,479E-03 0,04138503 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 5,479E-03 0,04121611 ! negative regulation of DNA binding GO:0043392 19 18 1,000 5,479E-03 0,04104857 ! B cell differentiation GO:0030183 18 18 1,000 5,479E-03 0,04088238 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 5,479E-03 0,04071753 ! regulation of microtubule-based process GO:0032886 18 18 1,000 5,479E-03 0,040554 ! negative regulation of catabolic process GO:0009895 18 18 1,000 5,479E-03 0,04039179 ! regulation of cell development GO:0060284 60 59 2,000 5,796E-03 0,04255907 ! protein localization in organelle GO:0033365 59 59 2,000 5,796E-03 0,04239019 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 6,099E-03 0,04443231 ! glial cell differentiation GO:0010001 19 19 1,000 6,099E-03 0,04425738 ! regulation of pH GO:0006885 19 19 1,000 6,099E-03 0,04408382 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 6,099E-03 0,04391161 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,099E-03 0,04374075 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 6,099E-03 0,04357121 ! regulation of protein stability GO:0031647 19 19 1,000 6,099E-03 0,04340299 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 6,099E-03 0,04323605 ! regulation of cell shape GO:0008360 21 19 1,000 6,099E-03 0,0430704 ! proteasomal protein catabolic process GO:0010498 62 61 2,000 6,362E-03 0,04474926 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! protein import GO:0017038 62 62 2,000 6,656E-03 0,04664371 ! negative regulation of binding GO:0051100 21 20 1,000 6,75E-03 0,04712542 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 6,75E-03 0,04694759 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 6,75E-03 0,04677109 ! chromatin remodeling GO:0006338 20 20 1,000 6,75E-03 0,04659592 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 6,75E-03 0,04642206 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 6,959E-03 0,04767694 ! angiogenesis GO:0001525 65 64 2,000 7,27E-03 0,0496215 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 7,27E-03 0,04943839 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 7,27E-03 0,04925663 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 7,432E-03 0,05017013 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 7,432E-03 0,04998702 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 7,432E-03 0,04980525 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 7,432E-03 0,0496248 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 7,916E-03 0,05266544 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 8,143E-03 0,05398081 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 22 22 1,000 8,143E-03 0,05378733 ! embryonic skeletal system development GO:0048706 22 22 1,000 8,143E-03 0,05359524 ! maintenance of protein location in cell GO:0032507 23 22 1,000 8,143E-03 0,05340451 ! regulation of adaptive immune response GO:0002819 22 22 1,000 8,143E-03 0,05321513 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 8,143E-03 0,05302709 ! striated muscle tissue development GO:0014706 69 67 2,000 8,251E-03 0,05354341 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 8,251E-03 0,05335554 ! Ras protein signal transduction GO:0007265 69 67 2,000 8,251E-03 0,05316898 ! response to radiation GO:0009314 70 68 2,000 8,594E-03 0,05519025 ! viral infectious cycle GO:0019058 23 23 1,000 8,883E-03 0,056844 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 8,883E-03 0,05664731 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 8,883E-03 0,05645198 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 8,883E-03 0,05625798 ! regionalization GO:0003002 70 69 2,000 8,946E-03 0,05646657 ! muscle tissue development GO:0060537 72 70 2,000 9,307E-03 0,05854031 ! mitochondrial transport GO:0006839 24 24 1,000 9,652E-03 0,0605067 ! gliogenesis GO:0042063 24 24 1,000 9,652E-03 0,06030159 ! maintenance of protein location GO:0045185 25 24 1,000 9,652E-03 0,06009787 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 1,000 9,652E-03 0,05989552 ! glucan metabolic process GO:0044042 25 24 1,000 9,652E-03 0,05969453 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! translational elongation GO:0006414 71 71 2,000 9,675E-03 0,05963846 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 0,01045017 0,06419889 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01045017 0,0639856 ! endosome transport GO:0016197 25 25 1,000 0,01045017 0,06377373 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01045017 0,06356325 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01045017 0,06335416 ! positive regulation of binding GO:0051099 27 26 1,000 0,01127644 0,06813927 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01127644 0,0679166 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01127644 0,06769537 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01127644 0,06747558 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 1,000 0,01127644 0,06725721 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01127644 0,06704025 ! double-strand break repair GO:0006302 27 26 1,000 0,01127644 0,06682469 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01127644 0,06661051 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01213062 0,07142725 ! learning or memory GO:0007611 28 27 1,000 0,01213062 0,07119977 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01213062 0,07097374 ! activation of caspase activity GO:0006919 27 27 1,000 0,01213062 0,07074914 ! cell growth GO:0016049 27 27 1,000 0,01213062 0,07052596 ! microtubule-based movement GO:0007018 82 78 2,000 0,01249556 0,07241922 ! nuclear transport GO:0051169 79 79 2,000 0,01293296 0,07471924 GO:0006913|nucleocytoplasmic transport, ! histone modification GO:0016570 28 28 1,000 0,01301234 0,07494296 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 0,01301234 0,0747095 ! viral reproductive process GO:0022415 29 29 1,000 0,01392125 0,07967972 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01392125 0,07943303 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01392125 0,07918787 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01392125 0,07894421 ! regulation of protein polymerization GO:0032271 29 29 1,000 0,01392125 0,07870205 ! response to UV GO:0009411 29 29 1,000 0,01392125 0,07846137 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,01477002 0,08299131 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01485699 0,08322624 GO:0043280|positive regulation of caspase activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,01485699 0,08297404 ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01485699 0,08272336 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,01485699 0,08247419 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01485699 0,08222652 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01485699 0,08198034 ! water-soluble vitamin metabolic process GO:0006767 30 30 1,000 0,01485699 0,08173562 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,0158192 0,0867702 ! membrane fusion GO:0006944 31 31 1,000 0,0158192 0,08651272 ! B cell activation GO:0042113 31 31 1,000 0,0158192 0,08625676 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 0,0158192 0,08600232 ! aging GO:0007568 32 31 1,000 0,0158192 0,08574937 ! regulation of DNA replication GO:0006275 32 31 1,000 0,0158192 0,08549791 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,0158192 0,08524791 ! regulation of translational initiation GO:0006446 31 31 1,000 0,0158192 0,08499938 ! heart development GO:0007507 90 87 2,000 0,01674812 0,08972902 ! muscle fiber development GO:0048747 32 32 1,000 0,01680753 0,08978632 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01680753 0,08952682 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01680753 0,08926882 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01680753 0,0890123 ! maintenance of location GO:0051235 33 32 1,000 0,01680753 0,08875725 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,01782164 0,09384365 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,01782164 0,09357629 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01782164 0,09331045 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01782164 0,09304611 ! regulation of actin filament length GO:0030832 34 34 1,000 0,01886117 0,09819531 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01886117 0,0979187 ! muscle cell differentiation GO:0042692 35 34 1,000 0,01886117 0,09764365 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,01886117 0,09737013 ! coenzyme biosynthetic process GO:0009108 34 34 1,000 0,01886117 0,09709815 ! secondary metabolic process GO:0019748 34 34 1,000 0,01886117 0,09682768 ! viral reproduction GO:0016032 34 34 1,000 0,01886117 0,09655872 ! DNA replication GO:0006260 91 91 2,000 0,0188684 0,09632813 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,01942078 0,09887432 ! regulation of cellular component size GO:0032535 35 35 1,000 0,01992579 0,10116593 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,01992579 0,100888 ! mesoderm development GO:0007498 35 35 1,000 0,01992579 0,1006116 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01992579 0,1003367 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,01992579 0,10006331 ! blood vessel development GO:0001568 95 94 2,000 0,02055241 0,10292959 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02101516 0,1049619 GO:0045937|positive regulation of phosphate metabolic process, ! heterocycle catabolic process GO:0046700 36 36 1,000 0,02101516 0,10467822 ! regulation of cell growth GO:0001558 97 96 2,000 0,02171989 0,1078969 ! vasculature development GO:0001944 97 96 2,000 0,02171989 0,10760686 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02212894 0,10933951 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 1,000 0,02212894 0,10904716 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,02212894 0,10875637 ! response to drug GO:0042493 37 37 1,000 0,02212894 0,10846712 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,02212894 0,10817941 ! adaptive immune response GO:0002250 37 37 1,000 0,02212894 0,10789322 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! blood circulation GO:0008015 99 98 2,000 0,02292326 0,11147113 GO:0003013|circulatory system process, ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,0232668 0,11284399 ! meiotic cell cycle GO:0051321 38 38 1,000 0,0232668 0,11254781 ! axon guidance GO:0007411 39 38 1,000 0,0232668 0,11225318 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,0232668 0,11196009 ! muscle organ development GO:0007517 102 100 2,000 0,02416254 0,1159676 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02442841 0,11693913 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,02442841 0,11663618 ! response to unfolded protein GO:0006986 39 39 1,000 0,02442841 0,11633479 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02442841 0,11603496 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02442841 0,11573667 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,02442841 0,11543991 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,02442841 0,11514466 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02561345 0,1204224 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,02561345 0,12011598 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02682158 0,12546237 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 1,000 0,02682158 0,12514474 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,0280525 0,13055745 ! protein ubiquitination GO:0016567 43 42 1,000 0,0280525 0,13022859 ! response to protein stimulus GO:0051789 42 42 1,000 0,0280525 0,12990138 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,02930587 0,13536521 ! mitochondrion organization GO:0007005 44 43 1,000 0,02930587 0,1350268 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,02930587 0,13469007 ! mRNA transport GO:0051028 44 44 1,000 0,03058139 0,14020276 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03058139 0,13985486 ! vitamin metabolic process GO:0006766 44 44 1,000 0,03058139 0,13950868 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,03058139 0,13916422 ! rRNA transcription GO:0009303 5 5 0,000 0,03087067 0,1401346 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03087067 0,13979029 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03087067 0,13944767 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03087067 0,13910672 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03087067 0,13876744 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03087067 0,1384298 ! reproductive cellular process GO:0048610 5 5 0,000 0,03087067 0,13809381 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03087067 0,13775944 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03087067 0,13742669 ! prostate gland development GO:0030850 5 5 0,000 0,03087067 0,13709554 ! metencephalon development GO:0022037 5 5 0,000 0,03087067 0,13676598 ! water transport GO:0006833 5 5 0,000 0,03087067 0,13643801 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03087067 0,1361116 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03087067 0,13578675 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03087067 0,13546345 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03087067 0,13514168 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03087067 0,13482144 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03087067 0,13450271 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03087067 0,13418549 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03087067 0,13386976 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03087067 0,13355551 ! filopodium assembly GO:0046847 7 5 0,000 0,03087067 0,13324274 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03087067 0,13293142 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03087067 0,13262156 ! GTP metabolic process GO:0046039 5 5 0,000 0,03087067 0,13231314 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03087067 0,13200614 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03087067 0,13170057 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03087067 0,13139642 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03087067 0,13109366 ! social behavior GO:0035176 5 5 0,000 0,03087067 0,1307923 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03087067 0,13049231 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03087067 0,1301937 ! memory GO:0007613 5 5 0,000 0,03087067 0,12989646 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03087067 0,12960057 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03087067 0,12930602 ! response to lipid GO:0033993 5 5 0,000 0,03087067 0,12901281 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03087067 0,12872092 ! hippocampus development GO:0021766 6 5 0,000 0,03087067 0,12843036 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03087067 0,1281411 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03087067 0,12785314 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03087067 0,12756648 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03087067 0,12728109 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03087067 0,12699698 ! heart looping GO:0001947 5 5 0,000 0,03087067 0,12671414 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03087067 0,12643255 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03087067 0,12615221 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03087067 0,12587312 ! pH reduction GO:0045851 5 5 0,000 0,03087067 0,12559525 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03087067 0,12531861 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03087067 0,12504318 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03087067 0,12476897 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03087067 0,12449595 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03087067 0,12422412 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03087067 0,12395348 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03087067 0,12368402 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03087067 0,12341572 ! adrenal gland development GO:0030325 5 5 0,000 0,03087067 0,12314859 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03087067 0,12288261 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03087067 0,12261778 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03087067 0,12235408 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03087067 0,12209152 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03087067 0,12183008 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03087067 0,12156976 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03087067 0,12131055 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03087067 0,12105244 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03087067 0,12079543 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03087067 0,12053951 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03087067 0,12028467 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03087067 0,1200309 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03087067 0,11977821 ! muscle cell migration GO:0014812 5 5 0,000 0,03087067 0,11952657 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03087067 0,11927599 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03087067 0,11902646 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03087067 0,11877797 ! response to ATP GO:0033198 5 5 0,000 0,03087067 0,11853052 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03087067 0,11828409 ! regulation of appetite GO:0032098 5 5 0,000 0,03087067 0,11803869 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03087067 0,1177943 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03087067 0,11755093 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03087067 0,11730855 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03087067 0,11706718 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03087067 0,11682679 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03087067 0,11658739 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03087067 0,11634897 ! fear response GO:0042596 5 5 0,000 0,03087067 0,11611153 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03087067 0,11587505 ! retinol metabolic process GO:0042572 5 5 0,000 0,03087067 0,11563953 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03087067 0,11540497 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03087067 0,11517135 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03087067 0,11493868 ! parturition GO:0007567 5 5 0,000 0,03087067 0,11470695 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03087067 0,11447615 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03087067 0,11424628 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03087067 0,11401733 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03087067 0,1137893 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03087067 0,11356217 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03087067 0,11333595 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03087067 0,11311063 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03087067 0,11288621 ! response to UV-B GO:0010224 5 5 0,000 0,03087067 0,11266267 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03087067 0,11244002 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03087067 0,11221824 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03087067 0,11199734 ! interaction with symbiont GO:0051702 5 5 0,000 0,03087067 0,11177731 ! cellular extravasation GO:0045123 5 5 0,000 0,03087067 0,11155813 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03087067 0,11133982 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03087067 0,11112236 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03087067 0,11090575 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03087067 0,11068998 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03087067 0,11047505 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03087067 0,11026095 ! response to amine stimulus GO:0014075 5 5 0,000 0,03087067 0,11004768 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03087067 0,10983523 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03087067 0,1096236 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03087067 0,10941279 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03087067 0,10920278 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03087067 0,10899358 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03087067 0,10878518 ! decidualization GO:0046697 5 5 0,000 0,03087067 0,10857757 ! hair follicle maturation GO:0048820 5 5 0,000 0,03087067 0,10837076 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03087067 0,10816473 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03087067 0,10795948 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03087067 0,10775502 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03087067 0,10755132 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03087067 0,10734839 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03087067 0,10714623 ! postreplication repair GO:0006301 5 5 0,000 0,03087067 0,10694483 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03087067 0,10674418 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03087067 0,10654429 ! histone methylation GO:0016571 5 5 0,000 0,03087067 0,10634514 ! DNA methylation GO:0006306 5 5 0,000 0,03087067 0,10614673 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03087067 0,10594907 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03087067 0,10575213 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03087067 0,10555593 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03087067 0,10536046 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03087067 0,10516571 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03087067 0,10497168 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03087067 0,10477836 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03087067 0,10458575 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03087067 0,10439385 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03087067 0,10420265 ! sterol catabolic process GO:0016127 5 5 0,000 0,03087067 0,10401215 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03087067 0,10382235 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03087067 0,10363324 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03087067 0,10344482 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03087067 0,10325708 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03087067 0,10307002 ! zymogen activation GO:0031638 5 5 0,000 0,03087067 0,10288363 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03087067 0,10269792 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03087067 0,10251288 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03087067 0,1023285 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03087067 0,10214479 ! nucleosome positioning GO:0016584 5 5 0,000 0,03087067 0,10196174 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03087067 0,10177934 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03087067 0,10159759 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03087067 0,10141649 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03087067 0,10123603 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03087067 0,10105621 ! NADPH regeneration GO:0006740 5 5 0,000 0,03087067 0,10087704 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03087067 0,10069849 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03087067 0,10052058 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03087067 0,1003433 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03087067 0,10016663 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03087067 0,09999059 ! sarcomere organization GO:0045214 5 5 0,000 0,03087067 0,09981517 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03087067 0,09964036 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03087067 0,09946617 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03087067 0,09929258 GO:0046325|negative regulation of glucose import, ! oocyte differentiation GO:0009994 5 5 0,000 0,03087067 0,0991196 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03087067 0,09894721 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03087067 0,09877543 ! spleen development GO:0048536 5 5 0,000 0,03087067 0,09860424 ! male genitalia development GO:0030539 5 5 0,000 0,03087067 0,09843365 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03087067 0,09826364 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03087067 0,09809422 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03087067 0,09792538 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03087067 0,09775713 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03087067 0,09758945 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03087067 0,09742234 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03087067 0,09725581 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03087067 0,09708984 ! ATP catabolic process GO:0006200 5 5 0,000 0,03087067 0,09692444 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03087067 0,09675961 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03087067 0,09659533 ! blastocyst formation GO:0001825 5 5 0,000 0,03087067 0,09643161 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03087067 0,09626844 ! embryonic gut development GO:0048566 5 5 0,000 0,03087067 0,09610582 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03087067 0,09594376 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03087067 0,09578224 ! activation of innate immune response GO:0002218 5 5 0,000 0,03087067 0,09562126 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03087067 0,09546082 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03087067 0,09530092 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03087067 0,09514155 ! muscle adaptation GO:0043500 5 5 0,000 0,03087067 0,09498272 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03087067 0,09482441 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03087067 0,09466664 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03087067 0,09450938 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03087067 0,09435265 ! defense response to fungus GO:0050832 5 5 0,000 0,03087067 0,09419644 ! lysogeny GO:0030069 5 5 0,000 0,03087067 0,09404074 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03087067 0,09388556 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03087067 0,09373089 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03087067 0,09357672 ! response to nicotine GO:0035094 5 5 0,000 0,03087067 0,09342307 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03087067 0,09326992 ! mitochondrion localization GO:0051646 5 5 0,000 0,03087067 0,09311726 ! nucleus localization GO:0051647 5 5 0,000 0,03087067 0,09296511 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03087067 0,09281346 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,03187875 0,09568818 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,03187875 0,09553259 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,03187875 0,0953775 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,03319764 0,09916247 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,03319764 0,09900201 ! tube morphogenesis GO:0035239 47 46 1,000 0,03319764 0,09884207 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,03453774 0,10266622 ! actin filament organization GO:0007015 50 48 1,000 0,03589876 0,10654013 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,03589876 0,10636884 ! DNA recombination GO:0006310 48 48 1,000 0,03589876 0,10619811 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03693214 0,10908001 ! axon extension GO:0048675 7 6 0,000 0,03693214 0,10890548 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03693214 0,10873151 ! tRNA modification GO:0006400 6 6 0,000 0,03693214 0,10855809 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03693214 0,10838523 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03693214 0,10821292 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03693214 0,10804115 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03693214 0,10786993 ! virus-host interaction GO:0019048 6 6 0,000 0,03693214 0,10769925 ! regulation of S phase GO:0033261 6 6 0,000 0,03693214 0,10752911 ! myotube differentiation GO:0014902 6 6 0,000 0,03693214 0,1073595 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03693214 0,10719043 ! bone remodeling GO:0046849 6 6 0,000 0,03693214 0,1070219 ! N-glycan processing GO:0006491 6 6 0,000 0,03693214 0,10685389 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03693214 0,1066864 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03693214 0,10651945 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03693214 0,10635301 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03693214 0,10618709 ! RNA methylation GO:0001510 6 6 0,000 0,03693214 0,10602169 ! cartilage condensation GO:0001502 7 6 0,000 0,03693214 0,1058568 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03693214 0,10569243 ! succinate metabolic process GO:0006105 7 6 0,000 0,03693214 0,10552857 ! artery development GO:0060840 6 6 0,000 0,03693214 0,10536521 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03693214 0,10520236 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03693214 0,10504001 ! androgen metabolic process GO:0008209 6 6 0,000 0,03693214 0,10487816 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03693214 0,10471681 ! limbic system development GO:0021761 7 6 0,000 0,03693214 0,10455595 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03693214 0,10439559 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03693214 0,10423572 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03693214 0,10407634 ! pathogenesis GO:0009405 6 6 0,000 0,03693214 0,10391744 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03693214 0,10375903 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03693214 0,1036011 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03693214 0,10344366 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03693214 0,10328669 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03693214 0,10313019 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03693214 0,10297417 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03693214 0,10281862 ! arginine metabolic process GO:0006525 6 6 0,000 0,03693214 0,10266354 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03693214 0,10250892 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03693214 0,10235478 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03693214 0,10220109 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03693214 0,10204786 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03693214 0,1018951 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03693214 0,10174279 ! V(D)J recombination GO:0033151 6 6 0,000 0,03693214 0,10159093 ! focal adhesion formation GO:0048041 7 6 0,000 0,03693214 0,10143953 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03693214 0,10128858 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,03693214 0,10113808 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03693214 0,10098802 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03693214 0,10083841 ! regulation of heart rate GO:0002027 6 6 0,000 0,03693214 0,10068924 ! lipid digestion GO:0044241 6 6 0,000 0,03693214 0,10054051 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03693214 0,10039222 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03693214 0,10024437 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03693214 0,10009695 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03693214 0,09994996 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03693214 0,09980341 ! ruffle organization GO:0031529 6 6 0,000 0,03693214 0,09965728 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03693214 0,09951159 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03693214 0,09936631 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03693214 0,09922147 ! L-amino acid transport GO:0015807 6 6 0,000 0,03693214 0,09907704 ! bone mineralization GO:0030282 6 6 0,000 0,03693214 0,09893303 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03693214 0,09878944 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03693214 0,09864627 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03693214 0,09850351 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03693214 0,09836116 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03693214 0,09821923 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03693214 0,0980777 ! regulation of organ growth GO:0046620 6 6 0,000 0,03693214 0,09793658 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03693214 0,09779587 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03693214 0,09765556 ! response to dsRNA GO:0043331 6 6 0,000 0,03693214 0,09751565 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03693214 0,09737615 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03693214 0,09723704 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,03693214 0,09709832 ! genitalia development GO:0048806 6 6 0,000 0,03693214 0,09696001 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03693214 0,09682208 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03693214 0,09668455 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,03693214 0,09654741 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03693214 0,09641066 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03693214 0,09627429 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03693214 0,09613831 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03693214 0,09600272 ! erythrocyte development GO:0048821 6 6 0,000 0,03693214 0,0958675 ! renal water homeostasis GO:0003091 6 6 0,000 0,03693214 0,09573267 ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03693214 0,09559821 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03693214 0,09546413 ! ribosome assembly GO:0042255 6 6 0,000 0,03693214 0,09533043 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03693214 0,0951971 ! diencephalon development GO:0021536 6 6 0,000 0,03693214 0,09506414 ! fucose catabolic process GO:0019317 6 6 0,000 0,03693214 0,09493156 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03693214 0,09479934 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03693214 0,09466749 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03693214 0,09453601 ! regulation of cell division GO:0051302 6 6 0,000 0,03693214 0,09440489 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03693214 0,09427414 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03693214 0,09414374 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03693214 0,09401371 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03693214 0,09388404 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03693214 0,09375472 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03693214 0,09362576 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03693214 0,09349715 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03693214 0,0933689 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03693214 0,09324099 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03693214 0,09311344 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03693214 0,09298624 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03693214 0,09285938 ! thymus development GO:0048538 6 6 0,000 0,03693214 0,09273287 ! lymph node development GO:0048535 6 6 0,000 0,03693214 0,0926067 ! organic cation transport GO:0015695 6 6 0,000 0,03693214 0,09248088 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03693214 0,09235539 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03693214 0,09223025 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03693214 0,09210545 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03693214 0,09198098 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03693214 0,09185685 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03693214 0,09173305 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03693214 0,09160959 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03693214 0,09148646 ! alditol metabolic process GO:0019400 6 6 0,000 0,03693214 0,09136366 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03693214 0,09124119 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03693214 0,09111904 ! maternal placenta development GO:0001893 6 6 0,000 0,03693214 0,09099723 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03693214 0,09087573 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03693214 0,09075457 ! localization within membrane GO:0051668 6 6 0,000 0,03693214 0,09063372 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,0372804 0,09136673 ! cofactor biosynthetic process GO:0051188 49 49 1,000 0,0372804 0,09124539 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,0372804 0,09112437 GO:0002696|positive regulation of leukocyte activation, ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,03868236 0,09442594 ! RNA transport GO:0050658 50 50 1,000 0,03868236 0,09430104 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03868236 0,09417647 ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,03868236 0,09405222 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03868236 0,09392831 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,04010434 0,09725302 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,04010434 0,09712522 ! RNA localization GO:0006403 52 52 1,000 0,04154605 0,10048474 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,04154605 0,10035304 ! cell fate commitment GO:0045165 52 52 1,000 0,04154605 0,10022169 ! response to light stimulus GO:0009416 53 52 1,000 0,04154605 0,10009068 ! respiratory burst GO:0045730 7 7 0,000 0,04295656 0,10335372 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04295656 0,10321897 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04295656 0,10308457 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04295656 0,10295052 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04295656 0,10281681 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04295656 0,10268346 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04295656 0,10255045 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04295656 0,10241778 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04295656 0,10228546 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04295656 0,10215348 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04295656 0,10202184 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04295656 0,10189054 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04295656 0,10175957 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04295656 0,10162894 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04295656 0,10149865 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04295656 0,10136869 ! axis specification GO:0009798 7 7 0,000 0,04295656 0,10123906 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04295656 0,10110977 ! visual behavior GO:0007632 7 7 0,000 0,04295656 0,1009808 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04295656 0,10085216 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04295656 0,10072385 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04295656 0,10059587 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04295656 0,10046821 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04295656 0,10034087 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04295656 0,10021386 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04295656 0,10008716 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04295656 0,09996079 ! digestive system development GO:0055123 7 7 0,000 0,04295656 0,09983474 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04295656 0,099709 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04295656 0,09958358 ! protein targeting to ER GO:0045047 8 7 0,000 0,04295656 0,09945848 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04295656 0,09933368 ! endoderm development GO:0007492 7 7 0,000 0,04295656 0,09920921 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04295656 0,09908504 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04295656 0,09896118 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04295656 0,09883764 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04295656 0,0987144 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04295656 0,09859146 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04295656 0,09846884 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,04295656 0,09834652 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04295656 0,0982245 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04295656 0,09810278 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04295656 0,09798137 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04295656 0,09786026 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04295656 0,09773944 ! UV protection GO:0009650 7 7 0,000 0,04295656 0,09761892 ! DNA integration GO:0015074 7 7 0,000 0,04295656 0,0974987 ! myofibril assembly GO:0030239 7 7 0,000 0,04295656 0,09737878 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04295656 0,09725915 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04295656 0,09713981 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04295656 0,09702077 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04295656 0,09690202 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04295656 0,09678355 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04295656 0,09666538 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04295656 0,0965475 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04295656 0,0964299 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04295656 0,09631259 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04295656 0,09619556 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04295656 0,09607882 ! eating behavior GO:0042755 7 7 0,000 0,04295656 0,09596236 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04295656 0,09584618 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04295656 0,09573029 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04295656 0,09561467 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04295656 0,09549933 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04295656 0,09538427 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04295656 0,09526949 ! induction of an organ GO:0001759 7 7 0,000 0,04295656 0,09515498 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04295656 0,09504075 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04295656 0,09492679 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04295656 0,09481311 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04295656 0,0946997 ! platelet activation GO:0030168 8 7 0,000 0,04295656 0,09458655 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04295656 0,09447368 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04295656 0,09436108 ! natural killer cell activation GO:0030101 7 7 0,000 0,04295656 0,09424875 ! NADP metabolic process GO:0006739 7 7 0,000 0,04295656 0,09413668 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04295656 0,09402488 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04295656 0,09391334 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04295656 0,09380207 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04295656 0,09369106 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04295656 0,09358031 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04295656 0,09346983 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04295656 0,09335961 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04295656 0,09324964 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04295656 0,09313994 ! cell-cell recognition GO:0009988 8 7 0,000 0,04295656 0,09303049 ! hormone catabolic process GO:0042447 7 7 0,000 0,04295656 0,0929213 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04295656 0,09281236 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04295656 0,09270368 ! oxygen transport GO:0015671 7 7 0,000 0,04295656 0,09259526 ! cell killing GO:0001906 7 7 0,000 0,04295656 0,09248709 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04295656 0,09237917 ! adult feeding behavior GO:0008343 7 7 0,000 0,04295656 0,0922715 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04295656 0,09216408 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04295656 0,09205691 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04295656 0,09195 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,04295656 0,09184333 ! response to cold GO:0009409 7 7 0,000 0,04295656 0,0917369 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,0430072 0,09173875 ! regulation of T cell activation GO:0050863 53 53 1,000 0,0430072 0,09163269 ! response to virus GO:0009615 54 54 1,000 0,04448751 0,09467724 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,04448751 0,09456803 ! in utero embryonic development GO:0001701 55 55 1,000 0,04598669 0,09764225 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,04598669 0,09752989 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04894418 0,10368289 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04894418 0,10356386 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04894418 0,10344509 ! positive regulation of translation GO:0045727 8 8 0,000 0,04894418 0,1033266 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04894418 0,10320837 ! superoxide anion generation GO:0042554 8 8 0,000 0,04894418 0,10309042 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04894418 0,10297274 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04894418 0,10285532 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04894418 0,10273818 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04894418 0,10262129 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04894418 0,10250468 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04894418 0,10238833 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04894418 0,10227224 ! zinc ion transport GO:0006829 8 8 0,000 0,04894418 0,10215642 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04894418 0,10204086 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04894418 0,10192556 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04894418 0,10181052 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04894418 0,10169574 ! lipid localization GO:0010876 8 8 0,000 0,04894418 0,10158121 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04894418 0,10146695 ! response to cAMP GO:0051591 8 8 0,000 0,04894418 0,10135294 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04894418 0,10123919 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04894418 0,10112569 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04894418 0,10101245 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04894418 0,10089946 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04894418 0,10078672 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04894418 0,10067424 ! sensory perception of taste GO:0050909 8 8 0,000 0,04894418 0,100562 ! organelle fusion GO:0048284 8 8 0,000 0,04894418 0,10045002 ! pancreas development GO:0031016 8 8 0,000 0,04894418 0,10033828 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04894418 0,1002268 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04894418 0,10011556 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04894418 0,10000457 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04894418 0,09989382 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04894418 0,09978332 ! sperm motility GO:0030317 8 8 0,000 0,04894418 0,09967306 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04894418 0,09956304 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04894418 0,09945327 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04894418 0,09934374 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04894418 0,09923445 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04894418 0,0991254 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04894418 0,0990166 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04894418 0,09890802 ! Golgi organization GO:0007030 8 8 0,000 0,04894418 0,09879969 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04894418 0,0986916 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04894418 0,09858374 ! fructose metabolic process GO:0006000 8 8 0,000 0,04894418 0,09847611 ! mannose metabolic process GO:0006013 9 8 0,000 0,04894418 0,09836872 ! sex determination GO:0007530 8 8 0,000 0,04894418 0,09826157 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04894418 0,09815464 ! response to fungus GO:0009620 8 8 0,000 0,04894418 0,09804795 ! stem cell differentiation GO:0048863 8 8 0,000 0,04894418 0,0979415 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04894418 0,09783527 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04894418 0,09772927 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04894418 0,0976235 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04894418 0,09751797 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04894418 0,09741265 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04894418 0,09730757 ! vasoconstriction GO:0042310 8 8 0,000 0,04894418 0,09720271 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04894418 0,09709808 ! muscle cell development GO:0055001 8 8 0,000 0,04894418 0,09699368 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04894418 0,09688949 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04894418 0,09678553 ! sensory perception of pain GO:0019233 8 8 0,000 0,04894418 0,0966818 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04894418 0,09657828 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04894418 0,09647499 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04894418 0,09637192 ! chromatin silencing GO:0006342 8 8 0,000 0,04894418 0,09626907 ! tissue regeneration GO:0042246 8 8 0,000 0,04894418 0,09616644 ! salivary gland development GO:0007431 8 8 0,000 0,04894418 0,09606402 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04894418 0,09596183 ! T cell homeostasis GO:0043029 8 8 0,000 0,04894418 0,09585985 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04894418 0,09575809 ! water homeostasis GO:0030104 8 8 0,000 0,04894418 0,09565654 ! cofactor transport GO:0051181 8 8 0,000 0,04894418 0,09555521 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04894418 0,09545409 ! acid secretion GO:0046717 8 8 0,000 0,04894418 0,09535319 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04894418 0,0952525 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04894418 0,09515202 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04894418 0,09505176 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04894418 0,0949517 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04894418 0,09485186 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04894418 0,09475222 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04894418 0,0946528 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04894418 0,09455358 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04894418 0,09445457 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04894418 0,09435577 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04894418 0,09425718 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04894418 0,09415879 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04894418 0,0940606 ! developmental induction GO:0031128 8 8 0,000 0,04894418 0,09396262 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04894418 0,09386485 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04894418 0,09376727 ! actin filament polymerization GO:0030041 9 8 0,000 0,04894418 0,0936699 ! peptide hormone processing GO:0016486 8 8 0,000 0,04894418 0,09357274 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04894418 0,09347577 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04894418 0,093379 ! innate immune response GO:0045087 58 58 1,000 0,05059466 0,09642809 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,05216654 0,09932121 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,05375591 0,10224162 ! protein polymerization GO:0051258 65 60 1,000 0,05375591 0,10213622 ! lactation GO:0007595 10 9 0,000 0,0548952 0,10419346 ! embryonic pattern specification GO:0009880 10 9 0,000 0,0548952 0,10408626 ! positive regulation of cell size GO:0045793 9 9 0,000 0,0548952 0,10397929 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,0548952 0,10387253 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,0548952 0,103766 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,0548952 0,10365968 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,0548952 0,10355358 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,0548952 0,10344769 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,0548952 0,10334203 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,0548952 0,10323658 ! copper ion transport GO:0006825 9 9 0,000 0,0548952 0,10313134 ! lipid phosphorylation GO:0046834 9 9 0,000 0,0548952 0,10302632 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,0548952 0,10292151 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,0548952 0,10281692 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,0548952 0,10271253 ! RNA polyadenylation GO:0043631 9 9 0,000 0,0548952 0,10260836 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,0548952 0,1025044 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,0548952 0,10240065 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,0548952 0,10229711 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,0548952 0,10219378 ! phospholipid efflux GO:0033700 9 9 0,000 0,0548952 0,10209066 ! response to alkaloid GO:0043279 10 9 0,000 0,0548952 0,10198775 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,0548952 0,10188504 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,0548952 0,10178254 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,0548952 0,10168025 ! response to ethanol GO:0045471 9 9 0,000 0,0548952 0,10157816 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,0548952 0,10147627 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,0548952 0,10137459 ! methionine metabolic process GO:0006555 9 9 0,000 0,0548952 0,10127312 ! glutamine metabolic process GO:0006541 9 9 0,000 0,0548952 0,10117185 ! cerebral cortex development GO:0021987 9 9 0,000 0,0548952 0,10107077 ! response to osmotic stress GO:0006970 9 9 0,000 0,0548952 0,10096991 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,0548952 0,10086924 ! central nervous system neuron development GO:0021954 10 9 0,000 0,0548952 0,10076877 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,0548952 0,1006685 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,0548952 0,10056843 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,0548952 0,10046857 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,0548952 0,10036889 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,0548952 0,10026942 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,0548952 0,10017014 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,0548952 0,10007106 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,0548952 0,09997218 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,0548952 0,09987349 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,0548952 0,099775 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,0548952 0,0996767 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,0548952 0,09957859 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,0548952 0,09948067 ! DNA replication initiation GO:0006270 9 9 0,000 0,0548952 0,09938295 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,0548952 0,09928542 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,0548952 0,09918808 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,0548952 0,09909094 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,0548952 0,09899398 GO:0002712|regulation of B cell mediated immunity, ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,0548952 0,09889721 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,0548952 0,09880063 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,0548952 0,09870424 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,0548952 0,09860804 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,0548952 0,09851202 ! collagen catabolic process GO:0030574 9 9 0,000 0,0548952 0,09841619 ! purine base metabolic process GO:0006144 9 9 0,000 0,0548952 0,09832055 ! gas transport GO:0015669 9 9 0,000 0,0548952 0,09822509 ! cholesterol efflux GO:0033344 9 9 0,000 0,0548952 0,09812982 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,0548952 0,09803473 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,0548952 0,09793983 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,0548952 0,09784511 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,0548952 0,09775058 ! defense response to virus GO:0051607 9 9 0,000 0,0548952 0,09765622 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,0548952 0,09756205 ! actin filament-based movement GO:0030048 9 9 0,000 0,0548952 0,09746806 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,0548952 0,09737425 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,05536249 0,09810873 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,05536249 0,09801448 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,05536249 0,09792042 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,05698604 0,10069537 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,05698604 0,10059892 ! axonogenesis GO:0007409 66 62 1,000 0,05698604 0,10050265 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,05698604 0,10040657 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,06028294 0,1061141 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,06028294 0,10601285 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06080984 0,10683749 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06080984 0,10673574 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06080984 0,10663419 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06080984 0,10653282 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06080984 0,10643165 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06080984 0,10633067 ! neuron maturation GO:0042551 10 10 0,000 0,06080984 0,10622989 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06080984 0,10612929 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06080984 0,10602888 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06080984 0,10592867 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06080984 0,10582864 ! hormone secretion GO:0046879 10 10 0,000 0,06080984 0,1057288 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06080984 0,10562915 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06080984 0,10552969 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,06080984 0,10543041 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06080984 0,10533133 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06080984 0,10523242 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06080984 0,10513371 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06080984 0,10503517 ! glial cell development GO:0021782 10 10 0,000 0,06080984 0,10493683 ! phototransduction GO:0007602 11 10 0,000 0,06080984 0,10483866 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06080984 0,10474068 ! fat cell differentiation GO:0045444 10 10 0,000 0,06080984 0,10464289 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06080984 0,10454527 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06080984 0,10444784 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06080984 0,10435059 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06080984 0,10425352 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06080984 0,10415663 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06080984 0,10405992 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06080984 0,10396339 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06080984 0,10386704 ! plasma membrane organization GO:0007009 10 10 0,000 0,06080984 0,10377086 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06080984 0,10367487 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,06080984 0,10357905 ! lysosomal transport GO:0007041 10 10 0,000 0,06080984 0,10348341 ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06080984 0,10338794 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06080984 0,10329266 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06080984 0,10319754 ! exocrine system development GO:0035272 10 10 0,000 0,06080984 0,1031026 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06080984 0,10300784 ! neuromuscular junction development GO:0007528 10 10 0,000 0,06080984 0,10291325 ! embryo implantation GO:0007566 11 10 0,000 0,06080984 0,10281884 ! regulation of protein binding GO:0043393 11 10 0,000 0,06080984 0,10272459 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06080984 0,10263052 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06080984 0,10253662 GO:0070585|protein localization in mitochondrion, ! protein export from nucleus GO:0006611 10 10 0,000 0,06080984 0,1024429 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06080984 0,10234934 ! cytolysis GO:0019835 10 10 0,000 0,06080984 0,10225596 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06080984 0,10216274 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06080984 0,1020697 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06080984 0,10197683 ! histone deacetylation GO:0016575 10 10 0,000 0,06080984 0,10188412 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06080984 0,10179158 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06080984 0,10169921 ! gland morphogenesis GO:0022612 10 10 0,000 0,06080984 0,10160701 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06080984 0,10151497 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06080984 0,10142311 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06080984 0,1013314 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06080984 0,10123987 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06080984 0,10114849 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06080984 0,10105729 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06080984 0,10096624 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06080984 0,10087537 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06080984 0,10078465 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06080984 0,1006941 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06080984 0,10060371 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06080984 0,10051348 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06080984 0,10042341 ! gut development GO:0048565 10 10 0,000 0,06080984 0,10033351 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06080984 0,10024377 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06080984 0,10015418 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06080984 0,10006476 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06080984 0,0999755 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,06364454 0,10454269 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,06364454 0,10444959 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,06534896 0,10715137 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! protein secretion GO:0009306 11 11 0,000 0,06668832 0,10925029 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06668832 0,10915326 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06668832 0,10905641 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06668832 0,10895973 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06668832 0,10886322 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06668832 0,10876688 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06668832 0,10867071 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06668832 0,10857471 ! skin development GO:0043588 11 11 0,000 0,06668832 0,10847888 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06668832 0,10838322 ! endothelial cell migration GO:0043542 11 11 0,000 0,06668832 0,10828773 ! peroxisomal transport GO:0043574 11 11 0,000 0,06668832 0,10819241 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06668832 0,10809725 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06668832 0,10800226 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06668832 0,10790744 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,06668832 0,10781279 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06668832 0,1077183 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06668832 0,10762397 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06668832 0,10752981 ! spinal cord development GO:0021510 11 11 0,000 0,06668832 0,10743582 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,06668832 0,10734199 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06668832 0,10724832 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,06668832 0,10715482 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06668832 0,10706148 ! digestive system process GO:0022600 11 11 0,000 0,06668832 0,1069683 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06668832 0,10687528 ! fucose metabolic process GO:0006004 11 11 0,000 0,06668832 0,10678243 ! membrane budding GO:0006900 11 11 0,000 0,06668832 0,10668974 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,06668832 0,1065972 ! monoamine transport GO:0015844 11 11 0,000 0,06668832 0,10650483 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06668832 0,10641262 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06668832 0,10632057 ! body fluid secretion GO:0007589 11 11 0,000 0,06668832 0,10622867 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06668832 0,10613694 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,06668832 0,10604536 ! membrane depolarization GO:0051899 11 11 0,000 0,06668832 0,10595394 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06668832 0,10586268 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,06668832 0,10577158 ! oogenesis GO:0048477 11 11 0,000 0,06668832 0,10568063 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06668832 0,10558984 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,06668832 0,10549921 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,06668832 0,10540873 ! muscle maintenance GO:0046716 12 11 0,000 0,06668832 0,1053184 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06668832 0,10522823 ! steroid catabolic process GO:0006706 11 11 0,000 0,06668832 0,10513822 ! endocrine process GO:0050886 11 11 0,000 0,06668832 0,10504835 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06668832 0,10495865 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06668832 0,10486909 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06668832 0,10477969 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,06668832 0,10469044 ! sensory perception of sound GO:0007605 71 69 1,000 0,06880379 0,10791948 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,06880379 0,10782771 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,06880379 0,1077361 ! regulation of translation GO:0006417 69 69 1,000 0,06880379 0,10764465 ! cell part morphogenesis GO:0032990 75 70 1,000 0,07055371 0,11028879 ! growth GO:0040007 70 70 1,000 0,07055371 0,11019532 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,07055371 0,11010202 GO:0016053|organic acid biosynthetic process, ! regulation of cell activation GO:0050865 71 71 1,000 0,07231829 0,11276025 ! translational initiation GO:0006413 12 12 0,000 0,07253086 0,11299609 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,07253086 0,11290065 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07253086 0,11280538 ! initiation of viral infection GO:0019059 12 12 0,000 0,07253086 0,11271027 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07253086 0,11261531 ! iron ion transport GO:0006826 13 12 0,000 0,07253086 0,11252052 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07253086 0,11242588 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07253086 0,11233141 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07253086 0,11223709 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07253086 0,11214293 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07253086 0,11204893 ! collagen metabolic process GO:0032963 12 12 0,000 0,07253086 0,11195509 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07253086 0,1118614 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07253086 0,11176787 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07253086 0,1116745 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07253086 0,11158128 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07253086 0,11148822 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07253086 0,11139531 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07253086 0,11130256 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07253086 0,11120996 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07253086 0,11111752 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07253086 0,11102523 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07253086 0,11093309 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07253086 0,11084111 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,07253086 0,11074927 ! acute-phase response GO:0006953 12 12 0,000 0,07253086 0,1106576 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07253086 0,11056607 ! vacuolar transport GO:0007034 12 12 0,000 0,07253086 0,11047469 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07253086 0,11038346 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07253086 0,11029239 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07253086 0,11020146 ! osteoblast differentiation GO:0001649 12 12 0,000 0,07253086 0,11011069 ! male gonad development GO:0008584 12 12 0,000 0,07253086 0,11002006 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07253086 0,10992958 ! renal system process GO:0003014 12 12 0,000 0,07253086 0,10983926 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07253086 0,10974908 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07253086 0,10965904 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,07253086 0,10956916 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07253086 0,10947942 ! pallium development GO:0021543 13 12 0,000 0,07253086 0,10938983 ! cell fate determination GO:0001709 12 12 0,000 0,07253086 0,10930039 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,07253086 0,10921109 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07253086 0,10912194 ! G1 phase GO:0051318 13 12 0,000 0,07253086 0,10903293 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07253086 0,10894407 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07253086 0,10885535 ! detection of light stimulus GO:0009583 13 12 0,000 0,07253086 0,10876678 ! synaptogenesis GO:0007416 12 12 0,000 0,07253086 0,10867835 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07253086 0,10859007 ! hormone transport GO:0009914 12 12 0,000 0,07253086 0,10850193 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07253086 0,10841393 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07253086 0,10832607 ! spermatid differentiation GO:0048515 13 12 0,000 0,07253086 0,10823836 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07253086 0,10815079 ! neural tube closure GO:0001843 13 12 0,000 0,07253086 0,10806336 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,07253086 0,10797607 ! negative regulation of translation GO:0017148 12 12 0,000 0,07253086 0,10788892 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,07409731 0,11013012 ! regulation of cytokine production GO:0001817 72 72 1,000 0,07409731 0,11004137 ! electron transport chain GO:0022900 75 74 1,000 0,07769769 0,11529536 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,07769769 0,1152026 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,07833767 0,11605814 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07833767 0,11596492 GO:0016444|somatic cell DNA recombination, ! phenol metabolic process GO:0018958 13 13 0,000 0,07833767 0,11587185 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,07833767 0,11577893 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,07833767 0,11568616 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07833767 0,11559354 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07833767 0,11550106 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07833767 0,11540873 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07833767 0,11531655 ! regeneration GO:0031099 13 13 0,000 0,07833767 0,11522452 ! keratinization GO:0031424 13 13 0,000 0,07833767 0,11513264 ! post-embryonic development GO:0009791 14 13 0,000 0,07833767 0,1150409 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07833767 0,1149493 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07833767 0,11485786 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07833767 0,11476655 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,07833767 0,1146754 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07833767 0,11458439 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07833767 0,11449352 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07833767 0,11440279 ! autophagy GO:0006914 13 13 0,000 0,07833767 0,11431221 ! actin filament bundle formation GO:0051017 13 13 0,000 0,07833767 0,11422178 ! ureteric bud development GO:0001657 13 13 0,000 0,07833767 0,11413148 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07833767 0,11404133 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07833767 0,11395132 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07833767 0,11386146 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07833767 0,11377173 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,07833767 0,11368215 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07833767 0,1135927 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07833767 0,1135034 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07833767 0,11341424 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07833767 0,11332522 ! vasodilation GO:0042311 14 13 0,000 0,07833767 0,11323633 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07833767 0,11314759 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07833767 0,11305899 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,07833767 0,11297052 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07833767 0,11288219 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07833767 0,112794 ! immunoglobulin production GO:0002377 13 13 0,000 0,07833767 0,11270595 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07833767 0,11261804 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,07833767 0,11253026 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07833767 0,11244262 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,07833767 0,11235512 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07833767 0,11226775 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07833767 0,11218052 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07833767 0,11209342 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07833767 0,11200646 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07833767 0,11191963 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07833767 0,11183294 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07833767 0,11174638 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07833767 0,11165996 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07833767 0,11157367 ! blastocyst development GO:0001824 13 13 0,000 0,07833767 0,11148751 ! telomere organization GO:0032200 13 13 0,000 0,07833767 0,11140149 GO:0000723|telomere maintenance, ! regulation of amine transport GO:0051952 13 13 0,000 0,07833767 0,11131559 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07833767 0,11122984 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,08320057 0,11804361 ! neuron fate commitment GO:0048663 14 14 0,000 0,08410896 0,11924063 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08410896 0,11914898 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08410896 0,11905747 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08410896 0,1189661 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08410896 0,11887486 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08410896 0,11878377 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08410896 0,11869282 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08410896 0,11860201 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08410896 0,11851133 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08410896 0,1184208 ! vesicle docking GO:0048278 14 14 0,000 0,08410896 0,1183304 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08410896 0,11824014 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08410896 0,11815002 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08410896 0,11806003 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08410896 0,11797018 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08410896 0,11788047 ! hair cycle GO:0042633 14 14 0,000 0,08410896 0,1177909 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08410896 0,11770146 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,08410896 0,11761216 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08410896 0,11752299 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08410896 0,11743396 ! lysosome organization GO:0007040 14 14 0,000 0,08410896 0,11734506 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08410896 0,1172563 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08410896 0,11716767 ! peptide transport GO:0015833 14 14 0,000 0,08410896 0,11707917 ! primary neural tube formation GO:0014020 15 14 0,000 0,08410896 0,11699081 ! peptide cross-linking GO:0018149 14 14 0,000 0,08410896 0,11690258 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08410896 0,11681449 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08410896 0,11672652 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08410896 0,11663869 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08410896 0,11655099 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08410896 0,11646343 ! collagen fibril organization GO:0030199 14 14 0,000 0,08410896 0,11637599 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08410896 0,11628869 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08410896 0,11620152 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08410896 0,11611447 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08410896 0,11602756 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08410896 0,11594078 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08410896 0,11585413 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08410896 0,1157676 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08410896 0,11568121 ! regulation of protein modification process GO:0031399 79 78 1,000 0,08506123 0,11690369 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,08506123 0,11681658 ! regulation of immune response GO:0050776 78 78 1,000 0,08506123 0,11672959 ! neuron projection development GO:0031175 85 80 1,000 0,08882073 0,12179807 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,08984496 0,12311097 ! positive regulation of ossification GO:0045778 15 15 0,000 0,08984496 0,1230195 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,08984496 0,12292818 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,08984496 0,12283698 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,08984496 0,12274593 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,08984496 0,122655 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,08984496 0,12256421 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,08984496 0,12247356 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,08984496 0,12238304 ! ovarian follicle development GO:0001541 15 15 0,000 0,08984496 0,12229265 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,08984496 0,1222024 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,08984496 0,12211228 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,08984496 0,12202229 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,08984496 0,12193244 ! heme metabolic process GO:0042168 15 15 0,000 0,08984496 0,12184272 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,08984496 0,12175313 ! chromosome condensation GO:0030261 15 15 0,000 0,08984496 0,12166367 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,08984496 0,12157434 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,08984496 0,12148515 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,08984496 0,12139608 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,08984496 0,12130715 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,08984496 0,12121834 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,08984496 0,12112967 ! phospholipid transport GO:0015914 15 15 0,000 0,08984496 0,12104112 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,08984496 0,12095271 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,08984496 0,12086442 ! glutathione metabolic process GO:0006749 16 15 0,000 0,08984496 0,12077626 ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,08984496 0,12068823 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,08984496 0,12060033 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,08984496 0,12051256 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,08984496 0,12042491 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,08984496 0,12033739 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,08984496 0,12025 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09554585 0,12778738 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,09554585 0,12769471 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09554585 0,12760218 ! learning GO:0007612 16 16 0,000 0,09554585 0,12750978 ! circadian rhythm GO:0007623 16 16 0,000 0,09554585 0,12741752 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09554585 0,12732539 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,09554585 0,12723339 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,09554585 0,12714152 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,09554585 0,12704979 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09554585 0,12695819 ! vesicle targeting GO:0006903 17 16 0,000 0,09554585 0,12686672 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09554585 0,12677538 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09554585 0,12668418 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09554585 0,12659311 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09554585 0,12650216 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,09554585 0,12641135 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09554585 0,12632067 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09554585 0,12623011 ! cell fate specification GO:0001708 16 16 0,000 0,09554585 0,12613969 ! pentose metabolic process GO:0019321 16 16 0,000 0,09554585 0,1260494 ! fatty acid transport GO:0015908 16 16 0,000 0,09554585 0,12595923 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09554585 0,1258692 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09554585 0,12577929 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09554585 0,12568951 ! polyol metabolic process GO:0019751 16 16 0,000 0,09554585 0,12559986 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09554585 0,12551034 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09554585 0,12542095 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09554585 0,12533168 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09554585 0,12524254 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09554585 0,12515352 GO:0043507|positive regulation of JUN kinase activity, ! regulation of coagulation GO:0050818 17 16 0,000 0,09554585 0,12506464 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,0964863 0,126206 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,09843196 0,12865965 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,09843196 0,12856846 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 0,1003889 0,13103169 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,1003889 0,13093896 GO:0006644|phospholipid metabolic process, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10121187 0,13191901 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,10121187 0,13182578 ! myelination GO:0042552 17 17 0,000 0,10121187 0,13173268 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10121187 0,13163971 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,10121187 0,13154688 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10121187 0,13145418 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10121187 0,1313616 ! sensory perception of smell GO:0007608 17 17 0,000 0,10121187 0,13126916 ! glucose transport GO:0015758 17 17 0,000 0,10121187 0,13117685 ! cell junction assembly GO:0034329 18 17 0,000 0,10121187 0,13108466 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10121187 0,13099261 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10121187 0,13090068 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10121187 0,13080889 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10121187 0,13071722 ! neural crest cell development GO:0014032 19 17 0,000 0,10121187 0,13062568 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,10121187 0,13053427 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,10121187 0,13044299 GO:0002764|immune response-regulating signal transduction, ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,10121187 0,13035183 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10121187 0,13026081 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10121187 0,13016991 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10121187 0,13007913 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10121187 0,12998848 ! embryonic organ development GO:0048568 17 17 0,000 0,10121187 0,12989796 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10121187 0,12980757 ! liver development GO:0001889 17 17 0,000 0,10121187 0,1297173 ! gene silencing GO:0016458 17 17 0,000 0,10121187 0,12962715 ! male gamete generation GO:0048232 90 88 1,000 0,10433581 0,13353534 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 1,000 0,10433581 0,13344267 GO:0033674|positive regulation of kinase activity, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,10684321 0,13655481 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,10684321 0,13646018 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,10684321 0,13636568 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,10684321 0,1362713 ! membrane docking GO:0022406 18 18 0,000 0,10684321 0,13617706 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,10684321 0,13608295 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,10684321 0,13598897 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,10684321 0,13589512 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,10684321 0,1358014 ! hexose transport GO:0008645 18 18 0,000 0,10684321 0,13570781 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,10684321 0,13561435 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,10684321 0,13552102 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,10684321 0,13542781 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,10684321 0,13533473 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,10684321 0,13524178 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,10684321 0,13514896 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,10684321 0,13505627 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,10684321 0,1349637 ! ensheathment of neurons GO:0007272 18 18 0,000 0,10684321 0,13487126 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,10684321 0,13477894 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,10684321 0,13468675 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,10684321 0,13459469 ! brain development GO:0007420 91 90 1,000 0,10832537 0,13636861 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,11033564 0,13880449 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,11235597 0,14124969 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11244008 0,14125908 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11244008 0,14116286 GO:0006956|complement activation, ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,11244008 0,14106676 ! feeding behavior GO:0007631 19 19 0,000 0,11244008 0,1409708 ! peroxisome organization GO:0007031 19 19 0,000 0,11244008 0,14087496 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11244008 0,14077926 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11244008 0,14068369 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,11244008 0,14058824 ! metanephros development GO:0001656 19 19 0,000 0,11244008 0,14049293 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11244008 0,14039775 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,11244008 0,14030269 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11244008 0,14020776 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11244008 0,14011296 ! peripheral nervous system development GO:0007422 19 19 0,000 0,11244008 0,14001829 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11244008 0,13992375 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11244008 0,13982933 ! eye morphogenesis GO:0048592 19 19 0,000 0,11244008 0,13973505 ! placenta development GO:0001890 19 19 0,000 0,11244008 0,13964088 ! response to heat GO:0009408 19 19 0,000 0,11244008 0,13954685 ! vesicle localization GO:0051648 20 19 0,000 0,11244008 0,13945294 ! tissue morphogenesis GO:0048729 94 93 1,000 0,11438616 0,14177114 ! cofactor metabolic process GO:0051186 95 94 1,000 0,11642602 0,14420239 ! regulation of muscle development GO:0048634 21 20 0,000 0,11800269 0,14605706 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,11800269 0,14595904 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,11800269 0,14586114 ! organic ether metabolic process GO:0018904 20 20 0,000 0,11800269 0,14576338 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,11800269 0,14566575 ! nucleus organization GO:0006997 20 20 0,000 0,11800269 0,14556825 ! phagocytosis GO:0006909 21 20 0,000 0,11800269 0,14547088 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11800269 0,14537364 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11800269 0,14527653 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11800269 0,14517955 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,11800269 0,1450827 ! lipid oxidation GO:0034440 20 20 0,000 0,11800269 0,14498598 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,11800269 0,14488938 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,11800269 0,14479292 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,11800269 0,14469658 ! RNA modification GO:0009451 20 20 0,000 0,11800269 0,14460038 ! single fertilization GO:0007338 21 20 0,000 0,11800269 0,1445043 ! regulation of B cell activation GO:0050864 20 20 0,000 0,11800269 0,14440834 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,12353125 0,15107372 ! mRNA catabolic process GO:0006402 21 21 0,000 0,12353125 0,15097354 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,12353125 0,15087349 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,12353125 0,15077357 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,12353125 0,15067379 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,12353125 0,15057413 ! Notch signaling pathway GO:0007219 22 21 0,000 0,12353125 0,15047461 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,12353125 0,15037523 ! ear morphogenesis GO:0042471 21 21 0,000 0,12353125 0,15027597 ! organic anion transport GO:0015711 21 21 0,000 0,12353125 0,15017684 ! cholesterol transport GO:0030301 21 21 0,000 0,12353125 0,15007785 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,12353125 0,14997898 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,12353125 0,14988024 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,12353125 0,14978164 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,12353125 0,14968316 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,12353125 0,14958482 ! regulation of proteolysis GO:0030162 21 21 0,000 0,12353125 0,1494866 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,12353125 0,14938851 ! response to other organism GO:0051707 101 100 1,000 0,12885761 0,15572759 ! RNA export from nucleus GO:0006405 22 22 0,000 0,12902595 0,15582885 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,12902595 0,1557268 ! sister chromatid segregation GO:0000819 22 22 0,000 0,12902595 0,15562489 ! regulation of ion transport GO:0043269 22 22 0,000 0,12902595 0,1555231 ! odontogenesis GO:0042476 22 22 0,000 0,12902595 0,15542145 ! cell junction organization GO:0034330 23 22 0,000 0,12902595 0,15531994 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,12902595 0,15521855 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,12902595 0,1551173 ! ovulation cycle process GO:0022602 22 22 0,000 0,12902595 0,15501618 ! spindle organization GO:0007051 22 22 0,000 0,12902595 0,1549152 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,12902595 0,15481434 ! cell chemotaxis GO:0060326 23 22 0,000 0,12902595 0,15471361 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,12902595 0,15461302 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,12902595 0,15451256 ! male sex differentiation GO:0046661 22 22 0,000 0,12902595 0,15441222 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,12902595 0,15431202 ! biopolymer methylation GO:0043414 22 22 0,000 0,12902595 0,15421195 GO:0032259|methylation, ! detection of external stimulus GO:0009581 23 22 0,000 0,12902595 0,15411201 ! neuron migration GO:0001764 22 22 0,000 0,12902595 0,15401219 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,12902595 0,15391251 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,12902595 0,15381295 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,12902595 0,15371353 ! aerobic respiration GO:0009060 22 22 0,000 0,12902595 0,15361423 ! cytokine production GO:0001816 22 22 0,000 0,12902595 0,15351506 ! cytokinesis GO:0000910 23 22 0,000 0,12902595 0,15341602 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,12902595 0,1533171 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,134487 0,15970331 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,134487 0,15960048 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,134487 0,15949777 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,134487 0,1593952 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,134487 0,15929276 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,134487 0,15919046 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,134487 0,15908828 ! endocrine system development GO:0035270 23 23 0,000 0,134487 0,15898624 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,134487 0,15888432 ! positive regulation of growth GO:0045927 23 23 0,000 0,134487 0,15878254 ! female gonad development GO:0008585 23 23 0,000 0,134487 0,15868088 ! lipid homeostasis GO:0055088 23 23 0,000 0,134487 0,15857936 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,134487 0,15847797 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,134487 0,1583767 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,134487 0,15827557 ! cell projection assembly GO:0030031 25 23 0,000 0,134487 0,15817456 ! regulation of action potential GO:0001508 24 24 0,000 0,1399146 0,1644532 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,1399146 0,16434838 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,1399146 0,1642437 ! glucose homeostasis GO:0042593 24 24 0,000 0,1399146 0,16413915 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,1399146 0,16403474 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,1399146 0,16393046 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,1399146 0,16382631 ! ovulation cycle GO:0042698 24 24 0,000 0,1399146 0,16372229 ! fertilization GO:0009566 25 24 0,000 0,1399146 0,16361841 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,1399146 0,16351465 ! negative regulation of secretion GO:0051048 26 25 0,000 0,14530895 0,16971128 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,14530895 0,1696038 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,14530895 0,16949646 ! cellular component disassembly GO:0022411 26 25 0,000 0,14530895 0,16938925 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,14530895 0,16928217 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,14530895 0,16917524 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,14530895 0,16906843 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,14530895 0,16896177 ! excretion GO:0007588 25 25 0,000 0,14530895 0,16885523 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,14530895 0,16874883 ! gastrulation GO:0007369 25 25 0,000 0,14530895 0,16864257 ! heart morphogenesis GO:0003007 25 25 0,000 0,14530895 0,16853644 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,14530895 0,16843044 ! regulation of endocytosis GO:0030100 25 25 0,000 0,14530895 0,16832458 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,14530895 0,16821884 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,14530895 0,16811325 ! positive regulation of defense response GO:0031349 26 26 0,000 0,15067025 0,17420657 ! glycolysis GO:0006096 26 26 0,000 0,15067025 0,17409735 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,15067025 0,17398827 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,15067025 0,17387932 ! cellular defense response GO:0006968 26 26 0,000 0,15067025 0,17377051 ! regulation of protein secretion GO:0050708 26 26 0,000 0,15067025 0,17366184 ! germ cell development GO:0007281 27 26 0,000 0,15067025 0,1735533 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,15067025 0,17344489 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,15067025 0,17333663 ! response to insulin stimulus GO:0032868 28 26 0,000 0,15067025 0,17322849 ! synapse organization GO:0050808 26 26 0,000 0,15067025 0,1731205 ! chloride transport GO:0006821 27 27 0,000 0,1559987 0,17913122 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,1559987 0,17901968 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,1559987 0,17890828 ! peptide metabolic process GO:0006518 29 27 0,000 0,1559987 0,17879702 ! mesenchymal cell development GO:0014031 29 27 0,000 0,1559987 0,17868589 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,1559987 0,17857491 ! defense response to bacterium GO:0042742 27 27 0,000 0,1559987 0,17846406 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,1559987 0,17835335 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1559987 0,17824278 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,16129449 0,18417952 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,16129449 0,18406548 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,16129449 0,18395158 ! carbohydrate transport GO:0008643 28 28 0,000 0,16129449 0,18383782 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,16129449 0,1837242 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,16129449 0,18361072 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,16129449 0,18349738 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,16129449 0,18338418 ! developmental growth GO:0048589 28 28 0,000 0,16129449 0,18327111 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,16129449 0,18315819 ! cartilage development GO:0051216 29 28 0,000 0,16129449 0,18304541 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,16655782 0,18890219 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,16655782 0,18878602 ! leukocyte migration GO:0050900 30 29 0,000 0,16655782 0,18866998 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,16655782 0,18855409 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,16655782 0,18843835 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,16655782 0,18832274 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,16655782 0,18820727 ! tRNA processing GO:0008033 29 29 0,000 0,16655782 0,18809195 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,16655782 0,18797677 ! adult behavior GO:0030534 30 29 0,000 0,16655782 0,18786173 ! transition metal ion transport GO:0000041 31 30 0,000 0,17178888 0,19364337 ! RNA catabolic process GO:0006401 30 30 0,000 0,17178888 0,19352501 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,17178888 0,19340679 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,17178888 0,19328871 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,17178888 0,19317078 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,17178888 0,193053 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,17178888 0,19293535 GO:0010863|positive regulation of phospholipase C activity, ! response to temperature stimulus GO:0009266 30 30 0,000 0,17178888 0,19281785 ! regulation of ossification GO:0030278 30 30 0,000 0,17178888 0,1927005 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,17178888 0,19258328 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,17178888 0,19246621 ! vesicle organization GO:0016050 30 30 0,000 0,17178888 0,19234928 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,17178888 0,19223249 ! establishment of organelle localization GO:0051656 31 30 0,000 0,17178888 0,19211585 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,17698787 0,19780998 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,17698787 0,19769009 ! ion transmembrane transport GO:0034220 31 31 0,000 0,17698787 0,19757035 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,17698787 0,19745076 ! digestion GO:0007586 31 31 0,000 0,17698787 0,19733131 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,17698787 0,197212 ! regulation of heart contraction GO:0008016 31 31 0,000 0,17698787 0,19709284 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,17698787 0,19697382 ! camera-type eye development GO:0043010 31 31 0,000 0,17698787 0,19685495 ! extracellular matrix organization GO:0030198 31 31 0,000 0,17698787 0,19673622 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,17698787 0,19661763 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,17698787 0,19649919 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,17698787 0,19638089 ! cell redox homeostasis GO:0045454 32 32 0,000 0,18215498 0,20199256 ! glucose catabolic process GO:0006007 32 32 0,000 0,18215498 0,2018711 ! lipid modification GO:0030258 32 32 0,000 0,18215498 0,20174978 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,18215498 0,20162861 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,18215498 0,20150758 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,18215498 0,2013867 ! cell maturation GO:0048469 32 32 0,000 0,18215498 0,20126597 ! nuclear export GO:0051168 32 32 0,000 0,18215498 0,20114538 ! kidney development GO:0001822 32 32 0,000 0,18215498 0,20102493 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,18215498 0,20090463 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,18215498 0,20078447 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1872904 0,2063217 ! amino acid transport GO:0006865 33 33 0,000 0,1872904 0,20619845 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,1872904 0,20607535 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1872904 0,20595239 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1872904 0,20582958 ! response to metal ion GO:0010038 34 34 0,000 0,19239431 0,21131271 ! ear development GO:0043583 34 34 0,000 0,19239431 0,21118685 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,19239431 0,21106114 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,19239431 0,21093559 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,19239431 0,21081018 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,19239431 0,21068492 ! detection of stimulus GO:0051606 36 34 0,000 0,19239431 0,21055981 ! acute inflammatory response GO:0002526 35 35 0,000 0,19746692 0,2159831 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,19746692 0,215855 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,19746692 0,21572705 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,19746692 0,21559925 ! regulation of immune effector process GO:0002697 35 35 0,000 0,19746692 0,2154716 ! hydrogen transport GO:0006818 36 36 0,000 0,2025084 0,220842 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,2025084 0,2207114 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2025084 0,22058096 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,2025084 0,22045067 ! regulation of mitosis GO:0007088 37 36 0,000 0,2025084 0,22032053 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2025084 0,22019055 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,2025084 0,22006072 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,2025084 0,21993104 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,2025084 0,21980152 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,2025084 0,21967215 ! gonad development GO:0008406 36 36 0,000 0,2025084 0,21954293 ! regulation of lipase activity GO:0060191 36 36 0,000 0,2025084 0,21941386 ! activation of immune response GO:0002253 36 36 0,000 0,2025084 0,21928495 ! coagulation GO:0050817 39 36 0,000 0,2025084 0,21915618 GO:0007596|blood coagulation, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,20751894 0,22444683 ! eye development GO:0001654 37 37 0,000 0,20751894 0,22431519 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,20751894 0,22418371 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,20751894 0,22405237 ! positive regulation of secretion GO:0051047 39 38 0,000 0,21249873 0,22929458 ! neurotransmitter transport GO:0006836 40 38 0,000 0,21249873 0,22916042 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,21249873 0,2290264 ! exocytosis GO:0006887 40 38 0,000 0,21249873 0,22889255 ! chromosome segregation GO:0007059 38 38 0,000 0,21249873 0,22875885 ! urogenital system development GO:0001655 38 38 0,000 0,21249873 0,22862531 ! hexose catabolic process GO:0019320 38 38 0,000 0,21249873 0,22849192 ! RNA elongation GO:0006354 38 38 0,000 0,21249873 0,22835869 ! regulation of neurological system process GO:0031644 38 38 0,000 0,21249873 0,22822561 ! hemostasis GO:0007599 42 39 0,000 0,21744794 0,2334051 ! activation of MAPK activity GO:0000187 39 39 0,000 0,21744794 0,23326924 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,21744794 0,23313354 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,21744794 0,232998 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,21744794 0,23286262 ! developmental maturation GO:0021700 39 39 0,000 0,21744794 0,23272739 ! limb development GO:0060173 39 39 0,000 0,21744794 0,23259232 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,22236678 0,23771576 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,22236678 0,23757795 ! organelle localization GO:0051640 41 40 0,000 0,22236678 0,23744031 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,22725541 0,24251981 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,22725541 0,24237947 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,22725541 0,24223928 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,22725541 0,24209926 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,22725541 0,2419594 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,23211401 0,24698968 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,23211401 0,24684716 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,23211401 0,2467048 ! forebrain development GO:0030900 43 42 0,000 0,23211401 0,24656261 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,23211401 0,24642058 ! reproductive structure development GO:0048608 43 43 0,000 0,23694278 0,25140216 ! alcohol catabolic process GO:0046164 43 43 0,000 0,23694278 0,25125751 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,23694278 0,25111302 ! humoral immune response GO:0006959 44 44 0,000 0,24174188 0,25605189 ! amine biosynthetic process GO:0009309 46 45 0,000 0,2465115 0,26095387 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,2465115 0,26080407 ! protein processing GO:0016485 45 45 0,000 0,2465115 0,26065444 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,25125181 0,26551438 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,25125181 0,26536222 ! regulation of membrane potential GO:0042391 46 46 0,000 0,25125181 0,26521024 ! regulation of blood pressure GO:0008217 48 47 0,000 0,25596298 0,27002849 ! sex differentiation GO:0007548 47 47 0,000 0,25596298 0,26987401 ! amine transport GO:0015837 47 47 0,000 0,25596298 0,26971971 ! rhythmic process GO:0048511 47 47 0,000 0,25596298 0,26956559 ! calcium ion transport GO:0006816 48 48 0,000 0,2606452 0,27433986 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,2606452 0,27418328 ! ossification GO:0001503 50 49 0,000 0,26529863 0,27891921 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,26529863 0,27876019 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,26529863 0,27860136 ! divalent metal ion transport GO:0070838 49 49 0,000 0,26529863 0,2784427 ! response to bacterium GO:0009617 50 49 0,000 0,26529863 0,27828422 ! regulation of defense response GO:0031347 50 50 0,000 0,26992345 0,28297436 ! chromatin assembly GO:0031497 50 50 0,000 0,26992345 0,28281349 GO:0006334|nucleosome assembly, ! transcription initiation GO:0006352 50 50 0,000 0,26992345 0,2826528 ! positive regulation of immune response GO:0050778 51 51 0,000 0,27451984 0,2873027 ! rRNA metabolic process GO:0016072 51 51 0,000 0,27451984 0,28713965 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,27451984 0,28697678 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,27451984 0,28681409 ! protein maturation GO:0051604 51 51 0,000 0,27451984 0,28665159 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,27908795 0,29125656 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,27908795 0,29109173 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,27908795 0,29092709 ! sodium ion transport GO:0006814 53 53 0,000 0,28362797 0,29549256 ! tRNA metabolic process GO:0006399 53 53 0,000 0,28362797 0,29532562 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,28362797 0,29515886 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,28362797 0,29499229 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,28814005 0,29951614 ! hormone metabolic process GO:0042445 55 54 0,000 0,28814005 0,2993473 ! sulfur metabolic process GO:0006790 55 54 0,000 0,28814005 0,29917865 ! nucleosome organization GO:0034728 55 55 0,000 0,29262437 0,30366369 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,29262437 0,30349281 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of cell adhesion GO:0030155 56 55 0,000 0,29262437 0,30332211 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,2970811 0,30776867 ! reproductive developmental process GO:0003006 56 56 0,000 0,2970811 0,30759576 ! extracellular structure organization GO:0043062 56 56 0,000 0,2970811 0,30742305 ! ATP metabolic process GO:0046034 57 57 0,000 0,30151039 0,31183145 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,30151039 0,31165656 ! dephosphorylation GO:0016311 60 59 0,000 0,31028735 0,3205491 ! carboxylic acid transport GO:0046942 59 59 0,000 0,31028735 0,32036952 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,31028735 0,32019014 ! immune effector process GO:0002252 59 59 0,000 0,31028735 0,32001096 ! potassium ion transport GO:0006813 60 60 0,000 0,31463534 0,32431372 ! cellular respiration GO:0045333 62 61 0,000 0,31895656 0,32858409 ! lipid transport GO:0006869 62 62 0,000 0,32325115 0,33282228 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,32325115 0,33263645 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,32325115 0,33245082 ! regulation of secretion GO:0051046 65 63 0,000 0,3275193 0,33665257 ! glucose metabolic process GO:0006006 63 63 0,000 0,3275193 0,33646492 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,3275193 0,33627747 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,3275193 0,33609024 ! anion transport GO:0006820 65 65 0,000 0,33597685 0,34457726 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,33597685 0,34438562 ! regulation of hormone levels GO:0010817 66 65 0,000 0,33597685 0,34419419 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,34016658 0,34829278 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,34016658 0,34809939 ! DNA packaging GO:0006323 66 66 0,000 0,34016658 0,34790622 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,34433048 0,35196954 ! muscle contraction GO:0006936 67 67 0,000 0,34433048 0,35177444 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,34846872 0,3558049 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,34846872 0,35560789 ! wound healing GO:0042060 74 70 0,000 0,3566688 0,36377454 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,36073095 0,36771412 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,36073095 0,36751085 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,36073095 0,36730781 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,36073095 0,36710499 ! secretion by cell GO:0032940 75 72 0,000 0,36476804 0,37100855 ! muscle system process GO:0003012 72 72 0,000 0,36476804 0,37080391 ! sensory organ development GO:0007423 72 72 0,000 0,36476804 0,3705995 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,37673049 0,38254231 ! response to oxidative stress GO:0006979 76 75 0,000 0,37673049 0,38233165 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,37673049 0,38212124 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,38066885 0,38590357 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,38066885 0,38569142 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,38458291 0,38944302 ! metal ion homeostasis GO:0055065 78 78 0,000 0,3884728 0,39316605 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,39618067 0,40074697 ! MAPKKK cascade GO:0000165 82 81 0,000 0,39999894 0,4043873 ! lipid catabolic process GO:0016042 82 81 0,000 0,39999894 0,4041656 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,40756486 0,41158468 ! ncRNA processing GO:0034470 83 83 0,000 0,40756486 0,41135928 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,41503757 0,41867227 ! hexose metabolic process GO:0019318 87 86 0,000 0,41873932 0,42217536 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,4260743 0,42933567 ! chemotaxis GO:0006935 90 89 0,000 0,42970781 0,43276038 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,42970781 0,43252403 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,43331885 0,43592066 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,43690755 0,43929112 ! visual perception GO:0007601 93 92 0,000 0,44047406 0,4426356 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,44047406 0,44239438 ! regulation of response to stress GO:0080134 97 94 0,000 0,44754099 0,4492473 ! epidermis development GO:0008544 94 94 0,000 0,44754099 0,44900274 ! endocytosis GO:0006897 99 98 0,000 0,46141429 0,46266949 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,46141429 0,46241791 ! regulation of system process GO:0044057 98 98 0,000 0,46141429 0,46216659 ! anti-apoptosis GO:0006916 100 99 0,000 0,46482909 0,46533406 ! ectoderm development GO:0007398 99 99 0,000 0,46482909 0,46508144 ! response to hormone stimulus GO:0009725 102 100 0,000 0,46822274 0,46822274