pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6390-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 80 42 4,000 3,592E-07 8,642E-04 ! T cell activation GO:0042110 168 81 5,000 4,081E-07 4,91E-04 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 2,000 4,097E-07 3,286E-04 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 5,724E-07 3,443E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 6,473E-07 3,115E-04 ! response to vitamin GO:0033273 31 20 3,000 6,473E-07 2,596E-04 ! reciprocal meiotic recombination GO:0007131 39 21 3,000 7,975E-07 2,741E-04 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 2,000 8,173E-07 2,458E-04 GO:0045625|regulation of T-helper 1 cell differentiation, ! positive regulation of intracellular transport GO:0032388 37 22 3,000 9,721E-07 2,599E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 1,051E-06 2,528E-04 ! interphase GO:0051325 213 98 5,000 1,262E-06 2,76E-04 ! cell cycle arrest GO:0007050 213 100 5,000 1,421E-06 2,849E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,427E-06 2,64E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 1,668E-06 2,866E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,668E-06 2,675E-04 ! negative regulation of cell development GO:0010721 73 25 3,000 1,668E-06 2,508E-04 GO:0050768|negative regulation of neurogenesis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,696E-06 2,401E-04 ! regulation of intracellular transport GO:0032386 101 57 4,000 1,696E-06 2,267E-04 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 2,194E-06 2,779E-04 ! ER overload response GO:0006983 12 8 2,000 2,277E-06 2,739E-04 ! regulation of T-helper 1 type immune response GO:0002825 9 8 2,000 2,277E-06 2,609E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 2,678E-06 2,928E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 3,806E-06 3,981E-04 ! negative regulation of ligase activity GO:0051352 112 68 4,000 4,096E-06 4,107E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 4,000 4,096E-06 3,942E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 4,000 4,404E-06 4,076E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 4,854E-06 4,326E-04 ! DNA damage checkpoint GO:0000077 71 33 3,000 5,28E-06 4,537E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 4,000 5,438E-06 4,512E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 4,000 5,438E-06 4,361E-04 ! meiosis GO:0007126 121 74 4,000 6,226E-06 4,832E-04 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 4,000 6,653E-06 5,002E-04 ! DNA integrity checkpoint GO:0031570 75 36 3,000 7,54E-06 5,497E-04 ! positive regulation of ligase activity GO:0051351 124 77 4,000 7,574E-06 5,36E-04 ! meiosis I GO:0007127 65 37 3,000 8,431E-06 5,796E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 4,000 8,592E-06 5,742E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 8,854E-06 5,758E-04 ! response to nutrient GO:0007584 125 82 4,000 1,032E-05 6,532E-04 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 2,000 1,148E-05 7,083E-04 ! response to X-ray GO:0010165 25 13 2,000 1,148E-05 6,906E-04 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 2,000 1,148E-05 6,738E-04 ! regulation of ligase activity GO:0051340 142 84 4,000 1,161E-05 6,65E-04 ! regulation of protein transport GO:0051223 154 87 4,000 1,378E-05 7,709E-04 GO:0070201|regulation of establishment of protein localization, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 2,000 1,458E-05 7,97E-04 ! response to gamma radiation GO:0010332 28 14 2,000 1,458E-05 7,793E-04 ! regulation of T-helper cell differentiation GO:0045622 26 15 2,000 1,817E-05 9,505E-04 ! detection of bacterium GO:0016045 18 15 2,000 1,817E-05 9,303E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 4,000 1,906E-05 9,555E-04 GO:0010498|proteasomal protein catabolic process, ! positive regulation of protein transport GO:0051222 72 46 3,000 2,034E-05 9,985E-04 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 2,000 2,231E-05 1,074E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 2,231E-05 1,053E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 2,000 2,231E-05 1,032E-03 ! regulation of protein localization GO:0032880 176 97 4,000 2,338E-05 1,061E-03 ! myoblast differentiation GO:0045445 45 17 2,000 2,702E-05 1,204E-03 ! centrosome cycle GO:0007098 25 18 2,000 3,234E-05 1,415E-03 ! response to retinoic acid GO:0032526 26 18 2,000 3,234E-05 1,39E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 2,000 3,234E-05 1,365E-03 ! response to vitamin A GO:0033189 27 19 2,000 3,831E-05 1,589E-03 ! regulation of interleukin-2 production GO:0032663 35 20 2,000 4,496E-05 1,833E-03 ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 5,232E-05 2,098E-03 ! cell aging GO:0007569 44 21 2,000 5,232E-05 2,064E-03 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 2,000 5,232E-05 2,03E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 5,232E-05 1,998E-03 ! detection of biotic stimulus GO:0009595 29 21 2,000 5,232E-05 1,967E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 2,000 6,043E-05 2,237E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 6,043E-05 2,203E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 7,902E-05 2,837E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 7,902E-05 2,796E-03 ! vasculogenesis GO:0001570 46 25 2,000 8,956E-05 3,123E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 8,956E-05 3,078E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 8,956E-05 3,035E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 1,01E-04 3,375E-03 ! microtubule organizing center organization GO:0031023 39 26 2,000 1,01E-04 3,328E-03 GO:0051297|centrosome organization, ! cell cycle checkpoint GO:0000075 137 69 3,000 1,013E-04 3,294E-03 ! benzene and derivative metabolic process GO:0042537 12 5 1,000 1,196E-04 3,836E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,196E-04 3,785E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,196E-04 3,736E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,196E-04 3,688E-03 ! tryptophan metabolic process GO:0006568 9 5 1,000 1,196E-04 3,642E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 1,196E-04 3,596E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 1,196E-04 3,552E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,196E-04 3,509E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,196E-04 3,466E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,196E-04 3,425E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 1,196E-04 3,385E-03 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 1,196E-04 3,346E-03 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 1,266E-04 3,501E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,33E-04 3,638E-03 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,402E-04 3,789E-03 ! steroid biosynthetic process GO:0006694 131 76 3,000 1,476E-04 3,945E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,714E-04 4,532E-03 ! male meiosis GO:0007140 7 6 1,000 1,79E-04 4,68E-03 ! response to interferon-gamma GO:0034341 15 6 1,000 1,79E-04 4,63E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,79E-04 4,58E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,79E-04 4,532E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 1,79E-04 4,485E-03 ! response to UV-C GO:0010225 11 6 1,000 1,79E-04 4,439E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,79E-04 4,393E-03 ! negative regulation of axon extension GO:0030517 21 6 1,000 1,79E-04 4,349E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 1,79E-04 4,306E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,888E-04 4,498E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 1,897E-04 4,476E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,897E-04 4,432E-03 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 1,897E-04 4,39E-03 ! negative regulation of protein transport GO:0051224 69 33 2,000 2,082E-04 4,771E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 2,485E-04 5,64E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,5E-04 5,621E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,5E-04 5,569E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,5E-04 5,518E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,5E-04 5,467E-03 GO:0043489|RNA stabilization, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 2,5E-04 5,418E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,5E-04 5,37E-03 ! centrosome duplication GO:0051298 13 7 1,000 2,5E-04 5,322E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,5E-04 5,276E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,5E-04 5,23E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 2,5E-04 5,185E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,5E-04 5,14E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,5E-04 5,097E-03 ! axonal fasciculation GO:0007413 18 7 1,000 2,5E-04 5,054E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,704E-04 5,421E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,325E-04 6,612E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,325E-04 6,558E-03 ! glycine catabolic process GO:0006546 13 8 1,000 3,325E-04 6,505E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 3,325E-04 6,452E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 3,325E-04 6,4E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,325E-04 6,35E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,325E-04 6,3E-03 ! blastocyst growth GO:0001832 19 8 1,000 3,325E-04 6,25E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,325E-04 6,202E-03 ! NAD biosynthetic process GO:0009435 13 8 1,000 3,325E-04 6,154E-03 ! T cell differentiation GO:0030217 81 41 2,000 3,986E-04 7,321E-03 ! regulation of T cell differentiation GO:0045580 70 41 2,000 3,986E-04 7,266E-03 ! skeletal muscle tissue development GO:0007519 186 99 3,000 4,072E-04 7,366E-03 GO:0060538|skeletal muscle organ development, ! induction of positive chemotaxis GO:0050930 15 9 1,000 4,266E-04 7,659E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 4,266E-04 7,602E-03 ! receptor clustering GO:0043113 18 9 1,000 4,266E-04 7,546E-03 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 4,266E-04 7,491E-03 ! double-strand break repair GO:0006302 81 44 2,000 4,915E-04 8,569E-03 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 4,915E-04 8,508E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 5,253E-04 9,027E-03 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 2,000 5,253E-04 8,963E-03 ! cell growth GO:0016049 84 45 2,000 5,253E-04 8,9E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 5,32E-04 8,951E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 5,32E-04 8,889E-03 ! lung alveolus development GO:0048286 26 10 1,000 5,32E-04 8,827E-03 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 5,32E-04 8,767E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 5,32E-04 8,707E-03 ! multicellular organism growth GO:0035264 18 10 1,000 5,32E-04 8,648E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 5,32E-04 8,59E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 5,32E-04 8,533E-03 GO:0045685|regulation of glial cell differentiation, ! negative regulation of axonogenesis GO:0050771 32 10 1,000 5,32E-04 8,477E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 5,32E-04 8,421E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 1,000 5,32E-04 8,366E-03 ! oocyte development GO:0048599 17 10 1,000 5,32E-04 8,311E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 5,32E-04 8,258E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 5,605E-04 8,645E-03 ! negative regulation of cell migration GO:0030336 115 46 2,000 5,605E-04 8,59E-03 ! regulation of adaptive immune response GO:0002819 84 47 2,000 5,972E-04 9,094E-03 ! activation of caspase activity GO:0006919 84 48 2,000 6,354E-04 9,615E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 6,354E-04 9,555E-03 ! negative regulation of muscle development GO:0048635 20 11 1,000 6,487E-04 9,695E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 6,487E-04 9,635E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 6,487E-04 9,576E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 6,487E-04 9,517E-03 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 6,487E-04 9,46E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of intracellular pH GO:0051453 19 11 1,000 6,487E-04 9,403E-03 ! neuroblast proliferation GO:0007405 24 11 1,000 6,487E-04 9,346E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 6,487E-04 9,291E-03 ! oocyte differentiation GO:0009994 18 11 1,000 6,487E-04 9,236E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 6,487E-04 9,181E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 6,752E-04 9,5E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 7,593E-04 0,01062129 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 7,767E-04 0,01080202 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 7,767E-04 0,01073994 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 7,767E-04 0,01067857 ! hippocampus development GO:0021766 26 12 1,000 7,767E-04 0,01061789 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 7,767E-04 0,0105579 ! cranial nerve development GO:0021545 20 12 1,000 7,767E-04 0,01049859 ! histone acetylation GO:0016573 26 12 1,000 7,767E-04 0,01043994 ! autonomic nervous system development GO:0048483 24 12 1,000 7,767E-04 0,01038194 ! peptidyl-lysine modification GO:0018205 21 12 1,000 7,767E-04 0,01032458 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 7,767E-04 0,01026785 ! biogenic amine catabolic process GO:0042402 23 12 1,000 7,767E-04 0,01021174 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 7,767E-04 0,01015625 ! regulation of angiogenesis GO:0045765 114 52 2,000 8,037E-04 0,01045308 ! response to UV GO:0009411 104 53 2,000 8,498E-04 0,0109929 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 9,158E-04 0,01178342 GO:0000725|recombinational repair, ! regulation of cellular pH GO:0030641 22 13 1,000 9,158E-04 0,01172074 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 1,000 9,158E-04 0,01165873 ! regulation of mRNA stability GO:0043488 31 13 1,000 9,158E-04 0,01159736 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 9,158E-04 0,01153664 ! positive regulation of caspase activity GO:0043280 95 55 2,000 9,469E-04 0,01186626 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 9,469E-04 0,01180478 ! aging GO:0007568 103 55 2,000 9,469E-04 0,01174393 ! negative regulation of cell motion GO:0051271 134 55 2,000 9,469E-04 0,01168371 ! skeletal muscle fiber development GO:0048741 111 56 2,000 9,98E-04 0,0122511 ! nucleotide-excision repair GO:0006289 83 56 2,000 9,98E-04 0,01218891 ! regulation of DNA replication GO:0006275 101 56 2,000 9,98E-04 0,01212735 ! muscle fiber development GO:0048747 112 57 2,000 1,051E-03 0,01270466 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,051E-03 0,01264114 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,066E-03 0,01276072 ! regulation of S phase GO:0033261 23 14 1,000 1,066E-03 0,01269755 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,066E-03 0,012635 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,066E-03 0,01257306 ! regulation of RNA stability GO:0043487 32 14 1,000 1,066E-03 0,01251173 ! regulation of axon extension GO:0030516 37 14 1,000 1,066E-03 0,01245099 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,066E-03 0,01239084 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 1,162E-03 0,01343663 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,227E-03 0,01412812 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,227E-03 0,01406085 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,227E-03 0,01399421 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 1,227E-03 0,0139282 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 1,399E-03 0,01580721 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,399E-03 0,01573334 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 1,399E-03 0,01566016 ! intermediate filament-based process GO:0045103 32 16 1,000 1,399E-03 0,01558766 ! axon cargo transport GO:0008088 43 16 1,000 1,399E-03 0,01551583 ! neuron recognition GO:0008038 35 16 1,000 1,399E-03 0,01544466 ! cellular amino acid derivative catabolic process GO:0042219 29 16 1,000 1,399E-03 0,01537413 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,399E-03 0,01530425 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,399E-03 0,015235 ! detection of external stimulus GO:0009581 91 63 2,000 1,405E-03 0,01522392 ! cellular amino acid catabolic process GO:0009063 101 63 2,000 1,405E-03 0,01515566 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,405E-03 0,015088 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,47E-03 0,01571999 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 1,537E-03 0,0163664 ! signal complex assembly GO:0007172 41 17 1,000 1,582E-03 0,01677177 ! limbic system development GO:0021761 36 17 1,000 1,582E-03 0,0166982 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,582E-03 0,01662529 ! glycine metabolic process GO:0006544 28 17 1,000 1,582E-03 0,016553 ! NAD metabolic process GO:0019674 29 17 1,000 1,582E-03 0,01648134 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,582E-03 0,0164103 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 1,582E-03 0,01633987 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,582E-03 0,01627005 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,678E-03 0,01717525 ! lung development GO:0030324 144 67 2,000 1,678E-03 0,01710247 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 1,678E-03 0,01703031 ! positive regulation of T cell activation GO:0050870 109 67 2,000 1,678E-03 0,01695875 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,751E-03 0,01762278 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,776E-03 0,01780567 ! patterning of blood vessels GO:0001569 39 18 1,000 1,776E-03 0,01773179 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,776E-03 0,01765852 ! aromatic compound catabolic process GO:0019439 27 18 1,000 1,776E-03 0,01758585 ! nerve development GO:0021675 28 18 1,000 1,776E-03 0,01751378 ! negative regulation of cell size GO:0045792 134 69 2,000 1,826E-03 0,01792739 ! respiratory tube development GO:0030323 150 70 2,000 1,902E-03 0,01860705 ! lipid phosphorylation GO:0046834 35 19 1,000 1,981E-03 0,01929257 ! forelimb morphogenesis GO:0035136 32 19 1,000 1,981E-03 0,01921478 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,981E-03 0,01913761 ! pigmentation during development GO:0048066 41 19 1,000 1,981E-03 0,01906106 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,981E-03 0,01898512 GO:0030968|endoplasmic reticulum unfolded protein response, ! plasma membrane fusion GO:0045026 28 19 1,000 1,981E-03 0,01890978 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,981E-03 0,01883504 ! amine catabolic process GO:0009310 117 71 2,000 1,981E-03 0,01876871 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 2,062E-03 0,01945888 ! respiratory system development GO:0060541 153 72 2,000 2,062E-03 0,01938287 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 2,196E-03 0,02055533 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,196E-03 0,02047566 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,196E-03 0,0203966 ! cellular response to starvation GO:0009267 33 20 1,000 2,196E-03 0,02031816 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 2,196E-03 0,02024031 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,196E-03 0,02016306 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,196E-03 0,02008639 ! regulation of transcription factor activity GO:0051090 126 74 2,000 2,23E-03 0,02032664 GO:0090046|regulation of transcription regulator activity, ! lymphocyte differentiation GO:0030098 167 75 2,000 2,317E-03 0,02104066 ! regulation of catabolic process GO:0009894 161 76 2,000 2,407E-03 0,02176814 ! hindlimb morphogenesis GO:0035137 43 21 1,000 2,421E-03 0,02181852 ! oogenesis GO:0048477 36 21 1,000 2,421E-03 0,02173711 ! positive regulation of locomotion GO:0040017 39 21 1,000 2,421E-03 0,0216563 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,421E-03 0,0215761 ! response to cytokine stimulus GO:0034097 63 21 1,000 2,421E-03 0,02149648 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 2,498E-03 0,02209533 ! protein oligomerization GO:0051259 139 78 2,000 2,591E-03 0,02283744 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,657E-03 0,02333417 ! microtubule-based transport GO:0010970 54 22 1,000 2,657E-03 0,02324932 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,657E-03 0,02316508 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 2,657E-03 0,02308145 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,657E-03 0,02299842 ! protein stabilization GO:0050821 39 22 1,000 2,657E-03 0,02291599 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 2,687E-03 0,0230873 ! muscle cell differentiation GO:0042692 159 80 2,000 2,784E-03 0,0238414 ! protein import into nucleus GO:0006606 158 80 2,000 2,784E-03 0,02375686 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 2,884E-03 0,02452167 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 2,000 2,884E-03 0,02443533 ! nuclear import GO:0051170 161 81 2,000 2,884E-03 0,02434959 ! regulation of neuron differentiation GO:0045664 167 81 2,000 2,884E-03 0,02426445 ! viral genome replication GO:0019079 41 23 1,000 2,904E-03 0,02434352 ! barbed-end actin filament capping GO:0051016 50 23 1,000 2,904E-03 0,02425899 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,904E-03 0,02417505 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,904E-03 0,02409169 ! response to oxygen levels GO:0070482 176 83 2,000 3,091E-03 0,02555258 ! regulation of behavior GO:0050795 43 24 1,000 3,161E-03 0,02604264 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,161E-03 0,02595376 ! pallium development GO:0021543 49 24 1,000 3,161E-03 0,02586548 ! protein tetramerization GO:0051262 52 24 1,000 3,161E-03 0,0257778 ! negative regulation of transport GO:0051051 153 84 2,000 3,197E-03 0,02598595 ! negative regulation of growth GO:0045926 155 84 2,000 3,197E-03 0,02589846 ! positive regulation of cell activation GO:0050867 145 85 2,000 3,306E-03 0,02668872 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 2,000 3,416E-03 0,02749172 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 3,428E-03 0,0274899 ! receptor metabolic process GO:0043112 46 25 1,000 3,428E-03 0,02739857 ! response to starvation GO:0042594 42 25 1,000 3,428E-03 0,02730785 ! somitogenesis GO:0001756 43 25 1,000 3,428E-03 0,02721772 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,428E-03 0,02712819 ! neural tube closure GO:0001843 49 25 1,000 3,428E-03 0,02703925 GO:0060606|tube closure, ! nitrogen compound catabolic process GO:0044270 143 87 2,000 3,53E-03 0,02775241 ! protein localization in nucleus GO:0034504 176 87 2,000 3,53E-03 0,02766201 ! positive regulation of protein modification process GO:0031401 136 88 2,000 3,645E-03 0,02847372 ! regulation of DNA binding GO:0051101 155 88 2,000 3,645E-03 0,02838157 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 3,705E-03 0,02875474 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 3,705E-03 0,02866228 ! tube lumen formation GO:0035148 50 26 1,000 3,705E-03 0,02857041 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 3,705E-03 0,02847913 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 3,705E-03 0,02838844 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,705E-03 0,02829831 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,705E-03 0,02820876 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 49 26 1,000 3,705E-03 0,02811978 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 1,000 3,705E-03 0,02803135 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 3,763E-03 0,02837952 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,992E-03 0,03001648 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,992E-03 0,02992297 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,992E-03 0,02983004 ! protein amino acid acylation GO:0043543 55 27 1,000 3,992E-03 0,02973769 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,992E-03 0,02964591 ! primary neural tube formation GO:0014020 51 27 1,000 3,992E-03 0,02955469 ! base-excision repair GO:0006284 41 27 1,000 3,992E-03 0,02946403 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 3,992E-03 0,02937393 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 3,992E-03 0,02928437 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 4,29E-03 0,03136994 ! dendrite development GO:0016358 59 28 1,000 4,29E-03 0,03127488 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 4,29E-03 0,03118039 ! vitamin biosynthetic process GO:0009110 39 28 1,000 4,29E-03 0,03108647 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 4,29E-03 0,03099312 ! regulation of T cell activation GO:0050863 158 94 2,000 4,386E-03 0,03159402 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 4,597E-03 0,03301523 ! regulation of pH GO:0006885 43 29 1,000 4,597E-03 0,03291697 ! response to organic cyclic substance GO:0014070 55 29 1,000 4,597E-03 0,0328193 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 4,597E-03 0,0327222 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 4,597E-03 0,03262567 ! tissue homeostasis GO:0001894 48 29 1,000 4,597E-03 0,03252972 GO:0048871|multicellular organismal homeostasis, ! leukocyte differentiation GO:0002521 202 96 2,000 4,652E-03 0,03282024 ! detection of stimulus GO:0051606 151 96 2,000 4,652E-03 0,03272428 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 4,788E-03 0,03358587 ! nicotinamide metabolic process GO:0006769 52 30 1,000 4,914E-03 0,03437001 GO:0046496|nicotinamide nucleotide metabolic process, ! carboxylic acid catabolic process GO:0046395 156 98 2,000 4,927E-03 0,03435934 GO:0016054|organic acid catabolic process, ! alkaloid metabolic process GO:0009820 53 31 1,000 5,241E-03 0,0364453 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 5,241E-03 0,03634028 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 5,241E-03 0,03623585 GO:0043433|negative regulation of transcription factor activity, ! regulation of axonogenesis GO:0050770 75 32 1,000 5,578E-03 0,03845361 ! hindbrain development GO:0030902 61 32 1,000 5,578E-03 0,03834375 ! positive regulation of catabolic process GO:0009896 64 32 1,000 5,578E-03 0,03823451 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 5,924E-03 0,04049381 ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 5,924E-03 0,0403791 ! glial cell differentiation GO:0010001 63 34 1,000 6,28E-03 0,04268484 ! xenobiotic metabolic process GO:0006805 51 34 1,000 6,28E-03 0,0425646 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 6,28E-03 0,04244504 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 6,28E-03 0,04232615 ! regulation of muscle development GO:0048634 70 35 1,000 6,646E-03 0,04466476 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 6,646E-03 0,04454034 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 6,646E-03 0,04441662 ! female gonad development GO:0008585 58 35 1,000 6,646E-03 0,04429358 ! telencephalon development GO:0021537 68 35 1,000 6,646E-03 0,04417123 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 6,646E-03 0,04404954 ! regulation of microtubule-based process GO:0032886 78 35 1,000 6,646E-03 0,04392853 ! neural tube formation GO:0001841 67 35 1,000 6,646E-03 0,04380817 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 7,021E-03 0,04615383 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 7,021E-03 0,04602807 ! tissue remodeling GO:0048771 76 37 1,000 7,405E-03 0,04841637 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 7,405E-03 0,04828516 ! negative regulation of DNA binding GO:0043392 68 37 1,000 7,405E-03 0,04815466 ! regulation of protein stability GO:0031647 73 37 1,000 7,405E-03 0,04802486 ! glycogen metabolic process GO:0005977 61 37 1,000 7,405E-03 0,04789576 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 7,405E-03 0,04776736 ! regulation of neuron projection development GO:0010975 91 38 1,000 7,799E-03 0,05017268 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 7,799E-03 0,05003889 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 7,799E-03 0,0499058 GO:0046660|female sex differentiation, ! embryonic epithelial tube formation GO:0001838 72 38 1,000 7,799E-03 0,04977343 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 7,799E-03 0,04964175 ! glucan metabolic process GO:0044042 62 38 1,000 7,799E-03 0,04951077 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 8,202E-03 0,05193214 ! segmentation GO:0035282 67 39 1,000 8,202E-03 0,05179583 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 8,202E-03 0,05166024 ! negative regulation of binding GO:0051100 72 40 1,000 8,614E-03 0,05411476 ! maintenance of protein location GO:0045185 91 40 1,000 8,614E-03 0,05397384 ! cytokinesis GO:0000910 72 40 1,000 8,614E-03 0,05383364 ! cellular amide metabolic process GO:0043603 67 41 1,000 9,036E-03 0,05632031 ! gliogenesis GO:0042063 88 41 1,000 9,036E-03 0,05617478 ! keratinocyte differentiation GO:0030216 62 41 1,000 9,036E-03 0,05603 ! female gamete generation GO:0007292 61 41 1,000 9,036E-03 0,05588596 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 9,036E-03 0,05574266 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 9,466E-03 0,05824836 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 9,466E-03 0,05809976 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 9,466E-03 0,05795193 ! neuron migration GO:0001764 79 42 1,000 9,466E-03 0,05780484 ! energy reserve metabolic process GO:0006112 74 43 1,000 9,905E-03 0,06033468 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 9,905E-03 0,06018232 ! neural tube development GO:0021915 77 43 1,000 9,905E-03 0,06003073 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 9,905E-03 0,0598799 ! B cell differentiation GO:0030183 107 44 1,000 0,0103536 0,06243297 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,0103536 0,06227689 ! developmental growth GO:0048589 82 44 1,000 0,0103536 0,06212158 ! maintenance of location in cell GO:0051651 97 44 1,000 0,0103536 0,06196705 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01081073 0,06454246 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01081073 0,0643827 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 0,01081073 0,06422373 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01127665 0,06682663 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01127665 0,06666244 ! pigmentation GO:0043473 100 46 1,000 0,01127665 0,06649905 ! response to insulin stimulus GO:0032868 95 46 1,000 0,01127665 0,06633646 ! endosome transport GO:0016197 108 47 1,000 0,01175129 0,06896 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01175129 0,06879221 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01175129 0,06862524 ! protein homooligomerization GO:0051260 76 47 1,000 0,01175129 0,06845908 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01223459 0,07110245 ! mitochondrial transport GO:0006839 82 48 1,000 0,01223459 0,07093112 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,01223459 0,07076061 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01272648 0,07342903 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01272648 0,07325336 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,0132269 0,07595206 ! histone modification GO:0016570 91 50 1,000 0,0132269 0,07577122 ! positive regulation of binding GO:0051099 78 51 1,000 0,01373578 0,07849948 ! viral infectious cycle GO:0019058 99 51 1,000 0,01373578 0,07831346 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01373578 0,07812832 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,01373578 0,07794406 ! chromatin remodeling GO:0006338 109 51 1,000 0,01373578 0,07776066 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,01373578 0,07757812 ! regulation of cell shape GO:0008360 125 51 1,000 0,01373578 0,07739644 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,01373578 0,07721561 ! membrane fusion GO:0006944 110 52 1,000 0,01425306 0,07993673 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01425306 0,07975083 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01425306 0,0795658 ! amino acid activation GO:0043038 92 52 1,000 0,01425306 0,07938162 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of translational initiation GO:0006446 82 53 1,000 0,01477868 0,08211892 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,01477868 0,08192971 ! cell maturation GO:0048469 100 53 1,000 0,01477868 0,08174136 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01477868 0,08155388 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,01477868 0,08136726 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01531257 0,08411423 ! cell recognition GO:0008037 85 54 1,000 0,01531257 0,08392262 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,01531257 0,08373189 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01585466 0,0864996 ! regulation of actin filament length GO:0030832 105 56 1,000 0,01640491 0,08929913 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01696324 0,09212993 ! lipid modification GO:0030258 97 57 1,000 0,01696324 0,09192243 ! maintenance of location GO:0051235 118 57 1,000 0,01696324 0,09171587 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01731203 0,0933918 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01731203 0,09318287 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01731203 0,09297487 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01731203 0,0927678 ! neuron fate determination GO:0048664 7 5 0,000 0,01731203 0,09256165 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01731203 0,09235642 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01731203 0,09215209 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01731203 0,09194866 ! polyol transport GO:0015791 12 5 0,000 0,01731203 0,09174613 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01731203 0,09154449 ! response to superoxide GO:0000303 10 5 0,000 0,01731203 0,09134374 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01731203 0,09114386 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,01731203 0,09094486 ! female meiosis GO:0007143 7 5 0,000 0,01731203 0,09074672 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01731203 0,09054944 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01731203 0,09035302 ! cobalt ion transport GO:0006824 11 5 0,000 0,01731203 0,09015745 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01731203 0,08996273 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01731203 0,08976884 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01731203 0,08957579 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01731203 0,08938357 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01731203 0,08919217 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01731203 0,08900159 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01731203 0,08881182 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01731203 0,08862286 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01731203 0,0884347 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01731203 0,08824734 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01731203 0,08806077 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01731203 0,08787499 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01731203 0,08768999 ! negative chemotaxis GO:0050919 14 5 0,000 0,01731203 0,08750576 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01731203 0,08732231 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01731203 0,08713963 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01731203 0,08695771 ! behavioral response to pain GO:0048266 9 5 0,000 0,01731203 0,08677655 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01731203 0,08659614 ! Notch receptor processing GO:0007220 8 5 0,000 0,01731203 0,08641648 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01731203 0,08623756 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01731203 0,08605939 ! micturition GO:0060073 9 5 0,000 0,01731203 0,08588195 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01731203 0,08570523 ! copulation GO:0007620 9 5 0,000 0,01731203 0,08552925 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01731203 0,08535398 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01731203 0,08517943 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01731203 0,0850056 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01731203 0,08483247 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01731203 0,08466005 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01731203 0,08448832 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01731203 0,08431729 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01731203 0,08414696 ! grooming behavior GO:0007625 6 5 0,000 0,01731203 0,08397731 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01731203 0,08380834 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01731203 0,08364005 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01731203 0,08347243 ! response to protozoan GO:0001562 10 5 0,000 0,01731203 0,08330549 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01731203 0,08313921 ! lymph vessel development GO:0001945 10 5 0,000 0,01731203 0,08297359 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01731203 0,08280864 ! endochondral ossification GO:0001958 16 5 0,000 0,01731203 0,08264433 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01731203 0,08248068 ! parathyroid gland development GO:0060017 13 5 0,000 0,01731203 0,08231768 ! anagen GO:0042640 6 5 0,000 0,01731203 0,08215531 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01731203 0,08199359 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01731203 0,0818325 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01731203 0,08167205 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01731203 0,08151222 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01731203 0,08135301 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01731203 0,08119443 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01731203 0,08103647 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01731203 0,08087911 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01731203 0,08072237 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01731203 0,08056624 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01731203 0,0804107 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01731203 0,08025577 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01731203 0,08010143 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01731203 0,07994768 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01731203 0,07979453 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01731203 0,07964196 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01731203 0,07948997 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01731203 0,07933856 ! histidine catabolic process GO:0006548 6 5 0,000 0,01731203 0,07918773 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01731203 0,07903746 ! microvillus organization GO:0032528 7 5 0,000 0,01731203 0,07888777 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01731203 0,07873865 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01731203 0,07859008 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01731203 0,07844208 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01731203 0,07829463 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01731203 0,07814774 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01731203 0,07800139 ! polyol catabolic process GO:0046174 7 5 0,000 0,01731203 0,0778556 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01731203 0,07771034 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01731203 0,07756563 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01731203 0,07742146 ! muscle cell migration GO:0014812 8 5 0,000 0,01731203 0,07727782 ! mitochondrial fission GO:0000266 8 5 0,000 0,01731203 0,07713471 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01731203 0,07699213 ! mRNA transcription GO:0009299 9 5 0,000 0,01731203 0,07685008 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01731203 0,07670855 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01731203 0,07656754 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01731203 0,07642705 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01731203 0,07628708 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01731203 0,07614761 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01731203 0,07600866 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01731203 0,07587021 ! response to food GO:0032094 6 5 0,000 0,01731203 0,07573226 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01731203 0,07559482 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01731203 0,07545787 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01731203 0,07532142 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01731203 0,07518546 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01731203 0,07504999 ! forebrain neuron development GO:0021884 13 5 0,000 0,01731203 0,07491501 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01731203 0,07478051 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01731203 0,07464649 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01731203 0,07451296 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01731203 0,0743799 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01731203 0,07424731 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01731203 0,0741152 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01731203 0,07398356 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01731203 0,07385238 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01731203 0,07372167 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01731203 0,07359142 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01731203 0,07346163 ! basic amino acid transport GO:0015802 11 5 0,000 0,01731203 0,0733323 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01731203 0,07320342 ! depyrimidination GO:0045008 10 5 0,000 0,01731203 0,07307499 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01731203 0,07294701 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01731203 0,07281948 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01731203 0,0726924 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01731203 0,07256576 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01731203 0,07243955 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01731203 0,07231379 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01731203 0,07218846 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01731203 0,07206357 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01731203 0,07193911 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01731203 0,07181508 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01731203 0,07169147 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01731203 0,07156829 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01731203 0,07144553 ! response to arsenic GO:0046685 10 5 0,000 0,01731203 0,07132319 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01731203 0,07120127 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01731203 0,07107977 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01731203 0,07095868 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01731203 0,070838 ! response to cadmium ion GO:0046686 7 5 0,000 0,01731203 0,07071773 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01731203 0,07059787 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01731203 0,07047842 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01731203 0,07035936 ! decidualization GO:0046697 11 5 0,000 0,01731203 0,07024071 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01731203 0,07012246 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01731203 0,07000461 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01731203 0,06988715 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01731203 0,06977009 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01731203 0,06965342 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01731203 0,06953713 ! neural tube patterning GO:0021532 7 5 0,000 0,01731203 0,06942124 ! embryonic cleavage GO:0040016 6 5 0,000 0,01731203 0,06930573 ! peroxisome fission GO:0016559 5 5 0,000 0,01731203 0,0691906 ! histone demethylation GO:0016577 10 5 0,000 0,01731203 0,06907586 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01731203 0,0689615 ! mitotic recombination GO:0006312 9 5 0,000 0,01731203 0,06884751 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01731203 0,0687339 ! metaphase plate congression GO:0051310 7 5 0,000 0,01731203 0,06862067 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01731203 0,0685078 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01731203 0,06839531 ! enteric nervous system development GO:0048484 8 5 0,000 0,01731203 0,06828319 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01731203 0,06817143 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01731203 0,06806004 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01731203 0,06794901 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01731203 0,06783834 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01731203 0,06772804 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01731203 0,06761809 ! plasminogen activation GO:0031639 5 5 0,000 0,01731203 0,0675085 ! B cell homeostasis GO:0001782 13 5 0,000 0,01731203 0,06739926 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01731203 0,06729038 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01731203 0,06718184 ! metaphase GO:0051323 8 5 0,000 0,01731203 0,06707366 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01731203 0,06696583 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01731203 0,06685834 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01731203 0,06675119 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01731203 0,06664439 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01731203 0,06653793 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01731203 0,06643181 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01731203 0,06632602 ! response to redox state GO:0051775 5 5 0,000 0,01731203 0,06622058 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01731203 0,06611547 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01731203 0,06601069 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01731203 0,06590624 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01731203 0,06580212 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01731203 0,06569833 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01731203 0,06559487 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01731203 0,06549174 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01731203 0,06538892 ! striatum development GO:0021756 9 5 0,000 0,01731203 0,06528643 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01731203 0,06518426 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01731203 0,06508241 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01731203 0,06498088 ! glial cell migration GO:0008347 11 5 0,000 0,01731203 0,06487966 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01731203 0,06477876 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01731203 0,06467817 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01731203 0,0645779 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01731203 0,06447793 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01731203 0,06437827 ! neuroprotection GO:0043526 6 5 0,000 0,01731203 0,06427893 ! neural plate development GO:0001840 8 5 0,000 0,01731203 0,06417988 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01731203 0,06408114 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01731203 0,06398271 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01731203 0,06388458 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01731203 0,06378674 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01731203 0,06368921 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01731203 0,06359198 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01731203 0,06349504 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01731203 0,06339839 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01731203 0,06330204 ! spindle assembly GO:0051225 6 5 0,000 0,01731203 0,06320598 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01731203 0,06311022 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01731203 0,06301474 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01731203 0,06291955 ! drug metabolic process GO:0017144 6 5 0,000 0,01731203 0,06282465 ! stem cell division GO:0017145 11 5 0,000 0,01731203 0,06273004 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01731203 0,0626357 ! organ regeneration GO:0031100 7 5 0,000 0,01731203 0,06254166 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01731203 0,06244789 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01731203 0,06235441 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01731203 0,0622612 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,0175296 0,06294957 ! regulation of cellular component size GO:0032535 109 59 1,000 0,01810391 0,06491507 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01810391 0,06481847 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01810391 0,06472216 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01868613 0,06670448 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,01927618 0,06870888 ! mesoderm development GO:0007498 119 61 1,000 0,01927618 0,06860724 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01927618 0,0685059 ! viral reproductive process GO:0022415 126 62 1,000 0,01987402 0,07052637 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,01987402 0,0704225 ! gonad development GO:0008406 98 62 1,000 0,01987402 0,07031894 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01987402 0,07021568 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02073864 0,07316302 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02073864 0,0730559 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02073864 0,07294909 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02073864 0,0728426 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02073864 0,07273641 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02073864 0,07263054 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02073864 0,07252497 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02073864 0,07241971 ! sleep GO:0030431 13 6 0,000 0,02073864 0,07231475 ! response to oxygen radical GO:0000305 11 6 0,000 0,02073864 0,0722101 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02073864 0,07210575 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02073864 0,0720017 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02073864 0,07189795 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02073864 0,0717945 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02073864 0,07169135 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02073864 0,07158849 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02073864 0,07148593 ! forebrain regionalization GO:0021871 8 6 0,000 0,02073864 0,07138366 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02073864 0,07128169 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02073864 0,07118 ! response to zinc ion GO:0010043 9 6 0,000 0,02073864 0,0710786 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02073864 0,0709775 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02073864 0,07087668 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02073864 0,07077614 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02073864 0,07067589 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02073864 0,07057593 ! malate metabolic process GO:0006108 11 6 0,000 0,02073864 0,07047624 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02073864 0,07037684 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02073864 0,07027772 ! protein refolding GO:0042026 15 6 0,000 0,02073864 0,07017887 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02073864 0,07008031 ! opsonization GO:0008228 8 6 0,000 0,02073864 0,06998202 ! mating behavior GO:0007617 7 6 0,000 0,02073864 0,06988401 ! neuron remodeling GO:0016322 15 6 0,000 0,02073864 0,06978627 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02073864 0,0696888 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02073864 0,0695916 ! equilibrioception GO:0050957 14 6 0,000 0,02073864 0,06949468 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02073864 0,06939802 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02073864 0,06930164 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02073864 0,06920552 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02073864 0,06910967 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02073864 0,06901408 ! toxin metabolic process GO:0009404 11 6 0,000 0,02073864 0,06891876 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02073864 0,0688237 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02073864 0,0687289 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02073864 0,06863436 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02073864 0,06854008 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02073864 0,06844606 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02073864 0,0683523 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02073864 0,0682588 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02073864 0,06816555 ! thymic T cell selection GO:0045061 12 6 0,000 0,02073864 0,06807255 ! protein lipoylation GO:0009249 10 6 0,000 0,02073864 0,06797981 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02073864 0,06788732 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02073864 0,06779508 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02073864 0,06770309 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02073864 0,06761135 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02073864 0,06751986 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02073864 0,06742862 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02073864 0,06733762 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02073864 0,06724687 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02073864 0,06715637 ! hyperosmotic response GO:0006972 9 6 0,000 0,02073864 0,0670661 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02073864 0,06697608 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02073864 0,0668863 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02073864 0,06679676 ! urea metabolic process GO:0019627 7 6 0,000 0,02073864 0,06670746 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02073864 0,0666184 ! neutrophil activation GO:0042119 8 6 0,000 0,02073864 0,06652957 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02073864 0,06644099 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02073864 0,06635263 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02073864 0,06626452 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02073864 0,06617663 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02073864 0,06608898 ! neuron apoptosis GO:0051402 9 6 0,000 0,02073864 0,06600156 ! nucleoside salvage GO:0043174 9 6 0,000 0,02073864 0,06591437 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02073864 0,06582741 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02073864 0,06574068 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02073864 0,06565418 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02073864 0,06556791 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02073864 0,06548186 ! carnitine transport GO:0015879 10 6 0,000 0,02073864 0,06539604 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02073864 0,06531044 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02073864 0,06522507 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02073864 0,06513992 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02073864 0,06505499 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02073864 0,06497029 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02073864 0,0648858 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02073864 0,06480153 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02073864 0,06471748 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02073864 0,06463365 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02073864 0,06455004 ! monocyte differentiation GO:0030224 12 6 0,000 0,02073864 0,06446664 ! astrocyte development GO:0014002 15 6 0,000 0,02073864 0,06438346 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02073864 0,06430049 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02073864 0,06421773 ! interaction with symbiont GO:0051702 13 6 0,000 0,02073864 0,06413519 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02073864 0,06405286 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02073864 0,06397074 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02073864 0,06388883 ! response to copper ion GO:0046688 10 6 0,000 0,02073864 0,06380714 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02073864 0,06372564 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02073864 0,06364436 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02073864 0,06356329 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02073864 0,06348242 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02073864 0,06340175 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02073864 0,06332129 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02073864 0,06324104 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02073864 0,06316099 ! hair follicle maturation GO:0048820 7 6 0,000 0,02073864 0,06308114 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02073864 0,06300149 ! Schwann cell development GO:0014044 15 6 0,000 0,02073864 0,06292204 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02073864 0,0628428 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02073864 0,06276375 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02073864 0,0626849 ! subpallium development GO:0021544 10 6 0,000 0,02073864 0,06260625 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02073864 0,06252779 ! histone ubiquitination GO:0016574 8 6 0,000 0,02073864 0,06244954 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02073864 0,06237147 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02073864 0,06229361 ! G2 phase GO:0051319 16 6 0,000 0,02073864 0,06221593 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02073864 0,06213846 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02073864 0,06206117 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02073864 0,06198407 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02073864 0,06190717 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02073864 0,06183046 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02073864 0,06175394 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02073864 0,0616776 ! receptor internalization GO:0031623 10 6 0,000 0,02073864 0,06160146 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02073864 0,0615255 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02073864 0,06144973 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02073864 0,06137414 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02073864 0,06129875 ! protein deubiquitination GO:0016579 14 6 0,000 0,02073864 0,06122353 ! protein destabilization GO:0031648 9 6 0,000 0,02073864 0,0611485 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02073864 0,06107366 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02073864 0,060999 ! regulation of viral transcription GO:0046782 10 6 0,000 0,02073864 0,06092452 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02073864 0,06085022 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02073864 0,0607761 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02073864 0,06070217 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02073864 0,06062841 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02073864 0,06055483 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02073864 0,06048143 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02073864 0,06040821 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02073864 0,06033516 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02073864 0,06026229 ! catecholamine transport GO:0051937 9 6 0,000 0,02073864 0,0601896 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02073864 0,06011708 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02073864 0,06004474 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02073864 0,05997257 ! maternal placenta development GO:0001893 12 6 0,000 0,02073864 0,05990058 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02073864 0,05982875 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02073864 0,0597571 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02073864 0,05968562 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02073864 0,05961431 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02073864 0,05954317 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02073864 0,0594722 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02073864 0,0594014 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,02171358 0,06211996 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,02171358 0,06204618 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,02234193 0,06376594 ! actin filament organization GO:0007015 148 66 1,000 0,02234193 0,06369039 ! secondary metabolic process GO:0019748 116 66 1,000 0,02234193 0,06361501 ! developmental maturation GO:0021700 116 66 1,000 0,02234193 0,06353982 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,02297776 0,06527094 ! adaptive immune response GO:0002250 119 67 1,000 0,02297776 0,06519397 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,02362101 0,0669401 ! viral reproduction GO:0016032 134 68 1,000 0,02362101 0,06686134 ! tRNA transcription GO:0009304 14 7 0,000 0,02415343 0,06828806 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02415343 0,06820791 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02415343 0,06812795 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02415343 0,06804817 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02415343 0,06796859 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02415343 0,06788918 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02415343 0,06780997 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02415343 0,06773093 ! prostate gland development GO:0030850 13 7 0,000 0,02415343 0,06765208 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02415343 0,06757342 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02415343 0,06749494 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02415343 0,06741664 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02415343 0,06733852 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02415343 0,06726058 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02415343 0,06718282 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02415343 0,06710524 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02415343 0,06702784 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02415343 0,06695062 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02415343 0,06687358 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02415343 0,06679671 ! glycolipid transport GO:0046836 10 7 0,000 0,02415343 0,06672002 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02415343 0,06664351 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02415343 0,06656717 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02415343 0,06649101 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02415343 0,06641502 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02415343 0,0663392 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02415343 0,06626356 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02415343 0,06618809 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02415343 0,06611279 ! pericardium development GO:0060039 14 7 0,000 0,02415343 0,06603766 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02415343 0,0659627 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02415343 0,06588791 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02415343 0,0658133 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02415343 0,06573885 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02415343 0,06566457 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02415343 0,06559045 ! lipoprotein transport GO:0042953 14 7 0,000 0,02415343 0,06551651 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02415343 0,06544273 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02415343 0,06536911 ! rhythmic behavior GO:0007622 15 7 0,000 0,02415343 0,06529566 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02415343 0,06522238 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02415343 0,06514926 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02415343 0,06507631 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02415343 0,06500351 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02415343 0,06493088 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02415343 0,06485842 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02415343 0,06478611 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02415343 0,06471397 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02415343 0,06464198 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02415343 0,06457016 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02415343 0,06449849 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02415343 0,06442699 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02415343 0,06435564 ! spinal cord patterning GO:0021511 13 7 0,000 0,02415343 0,06428445 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02415343 0,06421342 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02415343 0,06414254 ! adrenal gland development GO:0030325 17 7 0,000 0,02415343 0,06407182 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02415343 0,06400126 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02415343 0,06393085 ! ovulation GO:0030728 9 7 0,000 0,02415343 0,06386059 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02415343 0,06379049 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02415343 0,06372055 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02415343 0,06365076 ! microtubule nucleation GO:0007020 20 7 0,000 0,02415343 0,06358112 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02415343 0,06351163 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02415343 0,06344229 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02415343 0,06337311 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02415343 0,06330407 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02415343 0,06323519 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02415343 0,06316646 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02415343 0,06309787 ! galactose metabolic process GO:0006012 13 7 0,000 0,02415343 0,06302944 ! vesicle fusion GO:0006906 17 7 0,000 0,02415343 0,06296115 ! response to dietary excess GO:0002021 8 7 0,000 0,02415343 0,06289301 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02415343 0,06282502 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02415343 0,06275717 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02415343 0,06268947 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02415343 0,06262192 ! organ growth GO:0035265 15 7 0,000 0,02415343 0,06255451 ! purine salvage GO:0043101 10 7 0,000 0,02415343 0,06248725 ! nucleoside transport GO:0015858 8 7 0,000 0,02415343 0,06242013 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02415343 0,06235316 ! parturition GO:0007567 14 7 0,000 0,02415343 0,06228632 ! rRNA modification GO:0000154 14 7 0,000 0,02415343 0,06221964 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02415343 0,06215309 ! spindle checkpoint GO:0031577 15 7 0,000 0,02415343 0,06208669 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02415343 0,06202043 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02415343 0,06195431 ! macrophage differentiation GO:0030225 11 7 0,000 0,02415343 0,06188833 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02415343 0,06182249 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02415343 0,06175679 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02415343 0,06169123 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02415343 0,06162581 ! fibrinolysis GO:0042730 10 7 0,000 0,02415343 0,06156053 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02415343 0,06149539 ! eating behavior GO:0042755 7 7 0,000 0,02415343 0,06143038 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02415343 0,06136551 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02415343 0,06130078 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02415343 0,06123619 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02415343 0,06117173 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02415343 0,0611074 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02415343 0,06104321 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02415343 0,06097916 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02415343 0,06091524 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02415343 0,06085146 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02415343 0,0607878 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02415343 0,06072428 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02415343 0,0606609 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02415343 0,06059764 ! regulation of meiosis GO:0040020 12 7 0,000 0,02415343 0,06053452 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02415343 0,06047153 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02415343 0,06040867 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02415343 0,06034594 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02415343 0,06028334 ! transcription termination GO:0006353 13 7 0,000 0,02415343 0,06022087 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02415343 0,06015853 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02415343 0,06009632 ! anaphase GO:0051322 17 7 0,000 0,02415343 0,06003424 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02415343 0,05997228 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02415343 0,05991045 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02415343 0,05984875 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02415343 0,05978718 ! diuresis GO:0030146 12 7 0,000 0,02415343 0,05972574 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02415343 0,05966442 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02415343 0,05960322 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02415343 0,05954215 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02415343 0,05948121 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02415343 0,05942039 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02415343 0,05935969 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02415343 0,05929912 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02415343 0,05923868 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02415343 0,05917835 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02415343 0,05911815 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02415343 0,05905807 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02415343 0,05899811 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02415343 0,05893828 ! lymph node development GO:0048535 10 7 0,000 0,02415343 0,05887856 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02415343 0,05881897 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02415343 0,0587595 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02415343 0,05870014 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02415343 0,05864091 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02415343 0,0585818 ! adult feeding behavior GO:0008343 9 7 0,000 0,02415343 0,0585228 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02415343 0,05846392 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02415343 0,05840517 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02415343 0,05834653 ! muscle adaptation GO:0043500 14 7 0,000 0,02415343 0,058288 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02415343 0,0582296 ! retina homeostasis GO:0001895 12 7 0,000 0,02415343 0,05817131 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02415343 0,05811314 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02415343 0,05805509 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02415343 0,05799715 ! protein prenylation GO:0018342 18 7 0,000 0,02415343 0,05793932 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02415343 0,05788161 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02415343 0,05782402 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02415343 0,05776654 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02427162 0,05799157 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,02427162 0,05793404 ! antigen processing and presentation GO:0019882 104 69 1,000 0,02427162 0,05787662 ! appendage morphogenesis GO:0035107 135 70 1,000 0,02492953 0,05938659 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 0,0255947 0,06091082 ! appendage development GO:0048736 136 71 1,000 0,0255947 0,06085063 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,0255947 0,06079056 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,02626705 0,06232596 ! learning or memory GO:0007611 147 73 1,000 0,02694654 0,06387524 ! axon guidance GO:0007411 139 73 1,000 0,02694654 0,06381237 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02755641 0,06519245 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02755641 0,06512841 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02755641 0,0650645 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02755641 0,06500071 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02755641 0,06493705 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02755641 0,06487351 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02755641 0,06481009 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02755641 0,0647468 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02755641 0,06468363 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02755641 0,06462059 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02755641 0,06455767 ! meiotic prophase I GO:0007128 13 8 0,000 0,02755641 0,06449487 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02755641 0,06443219 ! oligopeptide transport GO:0006857 15 8 0,000 0,02755641 0,06436963 ! UTP metabolic process GO:0046051 8 8 0,000 0,02755641 0,0643072 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02755641 0,06424489 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02755641 0,06418269 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02755641 0,06412062 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02755641 0,06405867 ! succinate metabolic process GO:0006105 14 8 0,000 0,02755641 0,06399684 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02755641 0,06393512 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02755641 0,06387353 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02755641 0,06381205 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02755641 0,0637507 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02755641 0,06368946 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02755641 0,06362833 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02755641 0,06356733 ! reflex GO:0060004 16 8 0,000 0,02755641 0,06350644 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02755641 0,06344567 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02755641 0,06338501 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02755641 0,06332447 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02755641 0,06326405 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02755641 0,06320374 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02755641 0,06314355 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02755641 0,06308347 ! pigment granule organization GO:0048753 16 8 0,000 0,02755641 0,0630235 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02755641 0,06296365 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02755641 0,06290391 ! histidine metabolic process GO:0006547 16 8 0,000 0,02755641 0,06284429 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02755641 0,06278478 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02755641 0,06272538 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02755641 0,06266609 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02755641 0,06260692 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02755641 0,06254785 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02755641 0,0624889 ! melanin metabolic process GO:0006582 15 8 0,000 0,02755641 0,06243006 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02755641 0,06237133 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02755641 0,06231271 ! macrophage activation GO:0042116 12 8 0,000 0,02755641 0,0622542 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02755641 0,0621958 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02755641 0,06213751 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02755641 0,06207933 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02755641 0,06202126 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02755641 0,06196329 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02755641 0,06190544 ! osteoblast development GO:0002076 16 8 0,000 0,02755641 0,06184769 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02755641 0,06179005 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02755641 0,06173252 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02755641 0,06167509 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02755641 0,06161777 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02755641 0,06156056 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02755641 0,06150345 ! response to UV-B GO:0010224 16 8 0,000 0,02755641 0,06144645 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02755641 0,06138956 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02755641 0,06133277 ! intermediate filament organization GO:0045109 12 8 0,000 0,02755641 0,06127608 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02755641 0,0612195 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02755641 0,06116303 ! cellular extravasation GO:0045123 12 8 0,000 0,02755641 0,06110666 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02755641 0,06105039 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02755641 0,06099423 ! response to antibiotic GO:0046677 11 8 0,000 0,02755641 0,06093817 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02755641 0,06088221 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02755641 0,06082635 ! DNA topological change GO:0006265 12 8 0,000 0,02755641 0,0607706 ! response to tropane GO:0014073 15 8 0,000 0,02755641 0,06071495 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02755641 0,0606594 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02755641 0,06060395 ! melanosome transport GO:0032402 13 8 0,000 0,02755641 0,06054861 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02755641 0,06049336 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02755641 0,06043822 ! mast cell activation GO:0045576 14 8 0,000 0,02755641 0,06038317 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02755641 0,06032823 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02755641 0,06027339 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02755641 0,06021864 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02755641 0,060164 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02755641 0,06010945 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02755641 0,060055 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02755641 0,06000065 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02755641 0,0599464 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02755641 0,05989225 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02755641 0,0598382 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02755641 0,05978424 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02755641 0,05973038 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02755641 0,05967662 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02755641 0,05962295 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02755641 0,05956938 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02755641 0,05951591 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02755641 0,05946253 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02755641 0,05940925 ! hormone catabolic process GO:0042447 17 8 0,000 0,02755641 0,05935606 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02755641 0,05930297 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02755641 0,05924998 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02755641 0,05919707 ! ATP catabolic process GO:0006200 11 8 0,000 0,02755641 0,05914427 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02755641 0,05909155 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02755641 0,05903893 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02755641 0,05898641 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02755641 0,05893398 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02755641 0,05888164 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02755641 0,05882939 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02755641 0,05877724 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02755641 0,05872518 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02755641 0,05867321 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02755641 0,05862133 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02755641 0,05856954 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02755641 0,05851785 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02755641 0,05846625 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02755641 0,05841473 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02755641 0,05836331 GO:0000076|DNA replication checkpoint, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,0276331 0,05847426 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,02902722 0,06137037 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,02973467 0,06281089 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,03044897 0,06426334 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,03044897 0,06420702 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03094764 0,06520142 ! axon extension GO:0048675 15 9 0,000 0,03094764 0,06514438 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03094764 0,06508743 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03094764 0,06503059 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03094764 0,06497384 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03094764 0,0649172 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03094764 0,06486065 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03094764 0,0648042 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03094764 0,06474785 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03094764 0,06469159 ! phosphate transport GO:0006817 19 9 0,000 0,03094764 0,06463544 ! reproductive behavior GO:0019098 19 9 0,000 0,03094764 0,06457938 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03094764 0,06452342 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03094764 0,06446755 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03094764 0,06441179 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03094764 0,06435612 ! GTP metabolic process GO:0046039 9 9 0,000 0,03094764 0,06430054 ! RNA methylation GO:0001510 15 9 0,000 0,03094764 0,06424506 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03094764 0,06418968 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03094764 0,06413439 ! artery development GO:0060840 24 9 0,000 0,03094764 0,0640792 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03094764 0,0640241 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03094764 0,06396909 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03094764 0,06391419 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03094764 0,06385937 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03094764 0,06380465 ! chemosensory behavior GO:0007635 20 9 0,000 0,03094764 0,06375002 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03094764 0,06369549 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03094764 0,06364105 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03094764 0,0635867 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03094764 0,06353244 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03094764 0,06347828 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03094764 0,06342421 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03094764 0,06337023 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03094764 0,06331635 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03094764 0,06326255 ! protein targeting to ER GO:0045047 22 9 0,000 0,03094764 0,06320885 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03094764 0,06315524 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03094764 0,06310172 ! T cell selection GO:0045058 23 9 0,000 0,03094764 0,06304829 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03094764 0,06299495 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03094764 0,0629417 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03094764 0,06288854 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03094764 0,06283546 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03094764 0,06278248 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03094764 0,06272959 ! mannose metabolic process GO:0006013 13 9 0,000 0,03094764 0,06267679 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03094764 0,06262408 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03094764 0,06257145 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03094764 0,06251891 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03094764 0,06246646 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03094764 0,0624141 ! ruffle organization GO:0031529 15 9 0,000 0,03094764 0,06236183 ! retinol metabolic process GO:0042572 18 9 0,000 0,03094764 0,06230964 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03094764 0,06225755 ! behavioral fear response GO:0001662 22 9 0,000 0,03094764 0,06220554 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03094764 0,06215361 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03094764 0,06210177 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03094764 0,06205002 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03094764 0,06199836 ! protein heterooligomerization GO:0051291 16 9 0,000 0,03094764 0,06194678 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03094764 0,06189528 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03094764 0,06184388 ! segment specification GO:0007379 13 9 0,000 0,03094764 0,06179255 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03094764 0,06174131 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03094764 0,06169016 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03094764 0,06163909 ! response to amine stimulus GO:0014075 13 9 0,000 0,03094764 0,06158811 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03094764 0,06153721 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03094764 0,0614864 ! erythrocyte development GO:0048821 15 9 0,000 0,03094764 0,06143566 ! gas homeostasis GO:0033483 16 9 0,000 0,03094764 0,06138502 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03094764 0,06133445 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03094764 0,06128397 ! renal water homeostasis GO:0003091 14 9 0,000 0,03094764 0,06123357 ! postreplication repair GO:0006301 22 9 0,000 0,03094764 0,06118326 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03094764 0,06113303 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03094764 0,06108288 ! icosanoid secretion GO:0032309 15 9 0,000 0,03094764 0,06103281 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03094764 0,06098282 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03094764 0,06093292 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03094764 0,0608831 ! regulation of cell division GO:0051302 15 9 0,000 0,03094764 0,06083335 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03094764 0,06078369 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03094764 0,06073412 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03094764 0,06068462 ! sterol catabolic process GO:0016127 11 9 0,000 0,03094764 0,0606352 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03094764 0,06058586 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03094764 0,06053661 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03094764 0,06048743 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03094764 0,06043833 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03094764 0,06038932 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03094764 0,06034038 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03094764 0,06029152 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03094764 0,06024274 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03094764 0,06019404 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03094764 0,06014542 ! purine base metabolic process GO:0006144 21 9 0,000 0,03094764 0,06009687 ! pigment granule transport GO:0051904 17 9 0,000 0,03094764 0,06004841 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03094764 0,06000002 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03094764 0,05995171 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03094764 0,05990348 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03094764 0,05985533 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03094764 0,05980725 ! mitochondrion localization GO:0051646 15 9 0,000 0,03094764 0,05975925 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,03117006 0,06014047 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,03117006 0,06009228 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0318979 0,06144623 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,03263242 0,06281088 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,03337357 0,0641861 ! response to drug GO:0042493 143 82 1,000 0,03337357 0,06413483 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,03337357 0,06408365 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,03337357 0,06403254 ! regulation of lyase activity GO:0051339 160 83 1,000 0,0341213 0,06541502 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03432716 0,06575728 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03432716 0,06570497 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03432716 0,06565274 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03432716 0,06560059 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03432716 0,06554853 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03432716 0,06549655 ! synapsis GO:0007129 13 10 0,000 0,03432716 0,06544465 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03432716 0,06539283 ! N-glycan processing GO:0006491 20 10 0,000 0,03432716 0,06534109 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03432716 0,06528944 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03432716 0,06523787 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03432716 0,06518638 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03432716 0,06513497 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03432716 0,06508364 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03432716 0,0650324 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03432716 0,06498123 ! androgen metabolic process GO:0008209 17 10 0,000 0,03432716 0,06493014 ! phospholipid efflux GO:0033700 16 10 0,000 0,03432716 0,06487914 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03432716 0,06482821 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03432716 0,06477737 ! pathogenesis GO:0009405 13 10 0,000 0,03432716 0,0647266 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03432716 0,06467591 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03432716 0,06462531 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03432716 0,06457478 ! endoderm development GO:0007492 16 10 0,000 0,03432716 0,06452433 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03432716 0,06447396 ! arginine catabolic process GO:0006527 13 10 0,000 0,03432716 0,06442367 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03432716 0,06437346 ! proline metabolic process GO:0006560 13 10 0,000 0,03432716 0,06432332 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03432716 0,06427326 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03432716 0,06422328 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03432716 0,06417338 ! V(D)J recombination GO:0033151 28 10 0,000 0,03432716 0,06412356 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03432716 0,06407381 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03432716 0,06402414 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03432716 0,06397455 ! B cell proliferation GO:0042100 18 10 0,000 0,03432716 0,06392503 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03432716 0,06387559 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03432716 0,06382623 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03432716 0,06377694 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03432716 0,06372773 ! epithelial cell development GO:0002064 20 10 0,000 0,03432716 0,0636786 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03432716 0,06362954 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03432716 0,06358056 ! macroautophagy GO:0016236 17 10 0,000 0,03432716 0,06353165 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03432716 0,06348282 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03432716 0,06343406 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03432716 0,06338537 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03432716 0,06333677 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03432716 0,06328823 ! brain morphogenesis GO:0048854 23 10 0,000 0,03432716 0,06323977 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03432716 0,06319139 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03432716 0,06314308 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03432716 0,06309484 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03432716 0,06304667 ! response to dsRNA GO:0043331 20 10 0,000 0,03432716 0,06299858 ! DNA ligation GO:0006266 19 10 0,000 0,03432716 0,06295057 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03432716 0,06290262 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03432716 0,06285475 ! melanosome localization GO:0032400 16 10 0,000 0,03432716 0,06280695 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03432716 0,06275923 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03432716 0,06271157 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03432716 0,06266399 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03432716 0,06261648 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03432716 0,06256905 ! mRNA cleavage GO:0006379 17 10 0,000 0,03432716 0,06252168 ! protein sumoylation GO:0016925 15 10 0,000 0,03432716 0,06247439 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03432716 0,06242717 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03432716 0,06238002 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03432716 0,06233294 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03432716 0,06228593 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03432716 0,06223899 ! salivary gland development GO:0007431 27 10 0,000 0,03432716 0,06219213 ! prophase GO:0051324 15 10 0,000 0,03432716 0,06214533 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03432716 0,0620986 ! apical protein localization GO:0045176 15 10 0,000 0,03432716 0,06205195 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03432716 0,06200536 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03432716 0,06195885 ! midbrain development GO:0030901 13 10 0,000 0,03432716 0,0619124 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03432716 0,06186603 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03432716 0,06181972 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03432716 0,06177348 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03432716 0,06172731 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03432716 0,06168121 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03432716 0,06163518 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,03432716 0,06158922 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,03432716 0,06154333 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03432716 0,0614975 ! blastocyst formation GO:0001825 17 10 0,000 0,03432716 0,06145174 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03432716 0,06140605 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03432716 0,06136043 ! activation of innate immune response GO:0002218 12 10 0,000 0,03432716 0,06131488 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03432716 0,06126939 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03432716 0,06122398 ! response to nicotine GO:0035094 20 10 0,000 0,03432716 0,06117862 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03432716 0,06113334 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03432716 0,06108812 ! localization within membrane GO:0051668 20 10 0,000 0,03432716 0,06104297 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,03487555 0,06197236 ! response to unfolded protein GO:0006986 131 85 1,000 0,03563627 0,0632774 ! mitochondrion organization GO:0007005 148 86 1,000 0,03640341 0,0645919 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,03717691 0,06591574 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! respiratory burst GO:0045730 17 11 0,000 0,037695 0,06678511 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,037695 0,06673596 ! neuron fate specification GO:0048665 17 11 0,000 0,037695 0,06668689 ! telencephalon cell migration GO:0022029 20 11 0,000 0,037695 0,06663789 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,037695 0,06658897 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,037695 0,06654011 ! thyroid gland development GO:0030878 26 11 0,000 0,037695 0,06649133 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,037695 0,06644262 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,037695 0,06639398 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,037695 0,06634541 ! response to pain GO:0048265 24 11 0,000 0,037695 0,06629691 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,037695 0,06624848 ! T cell proliferation GO:0042098 26 11 0,000 0,037695 0,06620013 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,037695 0,06615184 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,037695 0,06610363 ! ventral spinal cord development GO:0021517 21 11 0,000 0,037695 0,06605548 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,037695 0,0660074 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,037695 0,0659594 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,037695 0,06591146 ! melanocyte differentiation GO:0030318 21 11 0,000 0,037695 0,0658636 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,037695 0,0658158 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,037695 0,06576807 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,037695 0,06572042 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,037695 0,06567283 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,037695 0,06562531 ! UV protection GO:0009650 19 11 0,000 0,037695 0,06557786 ! adult heart development GO:0007512 14 11 0,000 0,037695 0,06553047 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,037695 0,06548316 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,037695 0,06543591 ! temperature homeostasis GO:0001659 17 11 0,000 0,037695 0,06538873 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,037695 0,06534162 ! negative regulation of ossification GO:0030279 26 11 0,000 0,037695 0,06529458 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,037695 0,06524761 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,037695 0,0652007 ! regulation of organ growth GO:0046620 13 11 0,000 0,037695 0,06515386 ! pigment granule localization GO:0051875 20 11 0,000 0,037695 0,06510709 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,037695 0,06506038 ! vasoconstriction GO:0042310 18 11 0,000 0,037695 0,06501374 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,037695 0,06496717 ! embryonic axis specification GO:0000578 18 11 0,000 0,037695 0,06492067 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,037695 0,06487423 ! snRNA metabolic process GO:0016073 24 11 0,000 0,037695 0,06482786 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,037695 0,06478155 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,037695 0,06473531 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,037695 0,06468914 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,037695 0,06464303 ! zymogen activation GO:0031638 15 11 0,000 0,037695 0,06459699 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,037695 0,06455101 ! nucleosome positioning GO:0016584 15 11 0,000 0,037695 0,0645051 ! regulation of isotype switching GO:0045191 22 11 0,000 0,037695 0,06445926 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,037695 0,06441348 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,037695 0,06436776 ! acid secretion GO:0046717 18 11 0,000 0,037695 0,06432211 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,037695 0,06427652 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,037695 0,064231 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,037695 0,06418554 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,037695 0,06414015 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,037695 0,06409482 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,037695 0,06404956 ! cholesterol efflux GO:0033344 19 11 0,000 0,037695 0,06400436 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,037695 0,06395922 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,037695 0,06391415 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,037695 0,06386914 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,037695 0,06382419 ! embryonic gut development GO:0048566 15 11 0,000 0,037695 0,06377931 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,037695 0,06373449 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,037695 0,06368973 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,037695 0,06364503 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,037695 0,0636004 ! defense response to fungus GO:0050832 13 11 0,000 0,037695 0,06355583 ! developmental induction GO:0031128 19 11 0,000 0,037695 0,06351133 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,037695 0,06346688 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,037695 0,0634225 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,037695 0,06337818 ! sequestering of metal ion GO:0051238 14 11 0,000 0,037695 0,06333392 ! lamellipodium assembly GO:0030032 20 11 0,000 0,037695 0,06328972 ! nucleus localization GO:0051647 19 11 0,000 0,037695 0,06324559 ! regulation of synapse organization GO:0050807 17 11 0,000 0,037695 0,06320151 ! gland development GO:0048732 206 88 1,000 0,03795673 0,06359602 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,0387428 0,06486789 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,03953507 0,06614839 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03953507 0,06610242 ! sex differentiation GO:0007548 145 90 1,000 0,03953507 0,06605651 ! response to protein stimulus GO:0051789 149 91 1,000 0,0403335 0,06734379 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,0403335 0,06729709 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04105121 0,06844713 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04105121 0,06839973 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,04105121 0,0683524 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04105121 0,06830513 ! virus-host interaction GO:0019048 29 12 0,000 0,04105121 0,06825792 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04105121 0,06821078 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04105121 0,06816371 ! cartilage condensation GO:0001502 20 12 0,000 0,04105121 0,0681167 ! mating GO:0007618 17 12 0,000 0,04105121 0,06806975 ! protein complex disassembly GO:0043241 27 12 0,000 0,04105121 0,06802287 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04105121 0,06797606 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04105121 0,06792931 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04105121 0,06788262 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04105121 0,067836 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04105121 0,06778944 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04105121 0,06774294 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04105121 0,06769651 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04105121 0,06765015 ! drug transport GO:0015893 16 12 0,000 0,04105121 0,06760384 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04105121 0,0675576 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04105121 0,06751142 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04105121 0,06746531 ! focal adhesion formation GO:0048041 35 12 0,000 0,04105121 0,06741926 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04105121 0,06737327 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04105121 0,06732734 ! forebrain cell migration GO:0021885 21 12 0,000 0,04105121 0,06728148 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04105121 0,06723568 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04105121 0,06718994 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04105121 0,06714426 ! entry into host cell GO:0030260 32 12 0,000 0,04105121 0,06709865 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04105121 0,0670531 ! monoamine transport GO:0015844 18 12 0,000 0,04105121 0,06700761 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04105121 0,06696218 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04105121 0,06691681 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04105121 0,0668715 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04105121 0,06682626 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04105121 0,06678108 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04105121 0,06673595 ! protein homotetramerization GO:0051289 21 12 0,000 0,04105121 0,06669089 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04105121 0,06664589 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04105121 0,06660095 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04105121 0,06655607 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04105121 0,06651125 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04105121 0,0664665 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04105121 0,0664218 ! fucose catabolic process GO:0019317 22 12 0,000 0,04105121 0,06637716 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04105121 0,06633258 ! histone methylation GO:0016571 26 12 0,000 0,04105121 0,06628806 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04105121 0,0662436 ! gland morphogenesis GO:0022612 29 12 0,000 0,04105121 0,0661992 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04105121 0,06615486 ! T cell homeostasis GO:0043029 25 12 0,000 0,04105121 0,06611058 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04105121 0,06606636 ! spleen development GO:0048536 22 12 0,000 0,04105121 0,0660222 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04105121 0,0659781 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04105121 0,06593405 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04105121 0,06589007 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04105121 0,06584614 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04105121 0,06580227 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04105121 0,06575846 ! response to cold GO:0009409 17 12 0,000 0,04105121 0,06571471 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04105121 0,06567102 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04105121 0,06562738 ! vitamin metabolic process GO:0006766 139 92 1,000 0,04113803 0,06572251 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,04194861 0,06697303 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,04194861 0,06692862 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04194861 0,06688427 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,04276519 0,0681411 ! forebrain development GO:0030900 188 95 1,000 0,04358772 0,06940573 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04439583 0,07064574 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04439583 0,07059904 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04439583 0,07055241 ! peroxisomal transport GO:0043574 24 13 0,000 0,04439583 0,07050584 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04439583 0,07045934 ! lipid localization GO:0010876 28 13 0,000 0,04439583 0,07041289 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04439583 0,07036651 ! organelle fusion GO:0048284 32 13 0,000 0,04439583 0,07032018 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04439583 0,07027392 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04439583 0,07022772 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04439583 0,07018157 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04439583 0,07013549 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04439583 0,07008947 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04439583 0,07004351 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04439583 0,06999761 ! methionine metabolic process GO:0006555 27 13 0,000 0,04439583 0,06995177 ! plasma membrane organization GO:0007009 24 13 0,000 0,04439583 0,06990599 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04439583 0,06986027 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04439583 0,06981461 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04439583 0,06976901 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04439583 0,06972347 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04439583 0,06967799 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04439583 0,06963257 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04439583 0,0695872 ! exocrine system development GO:0035272 32 13 0,000 0,04439583 0,0695419 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,04439583 0,06949665 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04439583 0,06945147 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04439583 0,06940634 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04439583 0,06936127 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04439583 0,06931626 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04439583 0,06927131 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04439583 0,06922641 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04439583 0,06918158 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04439583 0,0691368 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04439583 0,06909208 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04439583 0,06904742 ! ribosome assembly GO:0042255 17 13 0,000 0,04439583 0,06900281 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,04439583 0,06895827 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04439583 0,06891378 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04439583 0,06886935 ! chromatin silencing GO:0006342 26 13 0,000 0,04439583 0,06882497 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04439583 0,06878065 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04439583 0,06873639 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04439583 0,06869219 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04439583 0,06864804 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04439583 0,06860395 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04439583 0,06855992 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04439583 0,06851594 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04439583 0,06847202 ! embryonic placenta development GO:0001892 23 13 0,000 0,04439583 0,06842816 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04439583 0,06838435 ! insulin secretion GO:0030073 23 13 0,000 0,04439583 0,0683406 ! actin filament polymerization GO:0030041 24 13 0,000 0,04439583 0,0682969 ! acrosome reaction GO:0007340 18 13 0,000 0,04439583 0,06825326 ! mRNA transport GO:0051028 169 96 1,000 0,04441615 0,06824091 ! protein ubiquitination GO:0016567 217 97 1,000 0,04525043 0,06947832 ! response to virus GO:0009615 160 98 1,000 0,0460905 0,07072306 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,04693633 0,07197502 ! rRNA transcription GO:0009303 25 14 0,000 0,04772889 0,07314376 ! lactation GO:0007595 26 14 0,000 0,04772889 0,0730972 ! reproductive cellular process GO:0048610 20 14 0,000 0,04772889 0,0730507 ! tRNA modification GO:0006400 20 14 0,000 0,04772889 0,07300426 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04772889 0,07295788 ! water transport GO:0006833 21 14 0,000 0,04772889 0,07291155 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04772889 0,07286529 ! non-recombinational repair GO:0000726 25 14 0,000 0,04772889 0,07281909 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04772889 0,07277294 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04772889 0,07272685 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04772889 0,07268082 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04772889 0,07263485 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04772889 0,07258894 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04772889 0,07254308 ! palate development GO:0060021 31 14 0,000 0,04772889 0,07249728 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04772889 0,07245154 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04772889 0,07240586 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04772889 0,07236024 ! arginine metabolic process GO:0006525 17 14 0,000 0,04772889 0,07231467 ! regulation of heart rate GO:0002027 24 14 0,000 0,04772889 0,07226916 ! organic alcohol transport GO:0015850 29 14 0,000 0,04772889 0,07222371 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04772889 0,07217831 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04772889 0,07213298 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04772889 0,07208769 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04772889 0,07204247 ! L-amino acid transport GO:0015807 30 14 0,000 0,04772889 0,0719973 ! bone mineralization GO:0030282 17 14 0,000 0,04772889 0,07195219 ! stem cell development GO:0048864 43 14 0,000 0,04772889 0,07190714 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04772889 0,07186214 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04772889 0,0718172 ! cerebellum development GO:0021549 21 14 0,000 0,04772889 0,07177231 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04772889 0,07172748 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04772889 0,07168271 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04772889 0,07163799 ! cofactor transport GO:0051181 26 14 0,000 0,04772889 0,07159333 ! NADP metabolic process GO:0006739 24 14 0,000 0,04772889 0,07154872 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04772889 0,07150417 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04772889 0,07145967 ! intestinal absorption GO:0050892 25 14 0,000 0,04772889 0,07141523 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04772889 0,07137085 ! oxygen transport GO:0015671 21 14 0,000 0,04772889 0,07132652 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04772889 0,07128225 ! male genitalia development GO:0030539 24 14 0,000 0,04772889 0,07123803 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04772889 0,07119386 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05105043 0,0761012 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05105043 0,07605408 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05105043 0,07600701 ! superoxide anion generation GO:0042554 20 15 0,000 0,05105043 0,07596001 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05105043 0,07591306 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05105043 0,07586617 ! copper ion transport GO:0006825 20 15 0,000 0,05105043 0,07581934 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05105043 0,07577257 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05105043 0,07572585 ! sulfate transport GO:0008272 23 15 0,000 0,05105043 0,0756792 ! response to cAMP GO:0051591 22 15 0,000 0,05105043 0,0756326 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05105043 0,07558605 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05105043 0,07553957 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05105043 0,07549314 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05105043 0,07544677 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05105043 0,07540045 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05105043 0,07535419 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05105043 0,07530799 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05105043 0,07526185 ! pituitary gland development GO:0021983 29 15 0,000 0,05105043 0,07521576 ! vesicle coating GO:0006901 33 15 0,000 0,05105043 0,07516973 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05105043 0,07512375 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05105043 0,07507783 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05105043 0,07503197 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05105043 0,07498616 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05105043 0,07494041 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05105043 0,07489472 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05105043 0,07484908 ! histone deacetylation GO:0016575 20 15 0,000 0,05105043 0,07480349 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05105043 0,07475796 ! tissue regeneration GO:0042246 26 15 0,000 0,05105043 0,07471249 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05105043 0,07466707 ! water homeostasis GO:0030104 27 15 0,000 0,05105043 0,07462171 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05105043 0,0745764 ! muscle maintenance GO:0046716 26 15 0,000 0,05105043 0,07453115 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05105043 0,07448595 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05105043 0,07444081 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05105043 0,07439572 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05105043 0,07435069 ! cell killing GO:0001906 29 15 0,000 0,05105043 0,07430571 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05105043 0,07426078 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,05105043 0,07421591 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05105043 0,0741711 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05105043 0,07412633 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05105043 0,07408163 ! peptide hormone processing GO:0016486 23 15 0,000 0,05105043 0,07403697 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0543605 0,07878998 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0543605 0,07874254 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0543605 0,07869516 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0543605 0,07864784 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0543605 0,07860058 ! bone remodeling GO:0046849 27 16 0,000 0,0543605 0,07855337 ! filopodium assembly GO:0046847 32 16 0,000 0,0543605 0,07850622 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0543605 0,07845912 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0543605 0,07841209 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0543605 0,07836511 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0543605 0,07831818 ! startle response GO:0001964 28 16 0,000 0,0543605 0,07827131 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0543605 0,0782245 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0543605 0,07817774 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0543605 0,07813104 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0543605 0,07808439 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0543605 0,0780378 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0543605 0,07799127 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0543605 0,07794479 ! response to osmotic stress GO:0006970 25 16 0,000 0,0543605 0,07789837 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0543605 0,077852 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0543605 0,07780569 ! fructose metabolic process GO:0006000 25 16 0,000 0,0543605 0,07775943 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0543605 0,07771323 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0543605 0,07766708 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0543605 0,07762099 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0543605 0,07757495 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0543605 0,07752896 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0543605 0,07748303 ! DNA replication initiation GO:0006270 27 16 0,000 0,0543605 0,07743716 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0543605 0,07739134 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0543605 0,07734557 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0543605 0,07729986 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0543605 0,0772542 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0543605 0,0772086 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0543605 0,07716304 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0543605 0,07711755 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0543605 0,0770721 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,0543605 0,07702671 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,0543605 0,07698138 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05765913 0,08160463 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05765913 0,08155666 ! metencephalon development GO:0022037 30 17 0,000 0,05765913 0,08150874 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05765913 0,08146088 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05765913 0,08141307 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05765913 0,08136532 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05765913 0,08131763 ! endothelial cell migration GO:0043542 28 17 0,000 0,05765913 0,08126999 ! inositol metabolic process GO:0006020 28 17 0,000 0,05765913 0,08122241 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05765913 0,08117488 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05765913 0,08112741 ! glial cell development GO:0021782 27 17 0,000 0,05765913 0,08108 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05765913 0,08103264 ! adult walking behavior GO:0007628 33 17 0,000 0,05765913 0,08098533 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05765913 0,08093808 ! heart looping GO:0001947 30 17 0,000 0,05765913 0,08089089 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05765913 0,08084375 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05765913 0,08079666 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05765913 0,08074963 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05765913 0,08070266 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05765913 0,08065574 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05765913 0,08060887 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,05765913 0,08056206 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05765913 0,08051531 ! membrane budding GO:0006900 37 17 0,000 0,05765913 0,0804686 ! DNA integration GO:0015074 29 17 0,000 0,05765913 0,08042195 ! regulation of protein binding GO:0043393 33 17 0,000 0,05765913 0,08037536 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05765913 0,08032882 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05765913 0,08028233 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05765913 0,0802359 ! genitalia development GO:0048806 30 17 0,000 0,05765913 0,08018952 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05765913 0,0801432 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05765913 0,08009692 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05765913 0,0800507 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05765913 0,08000454 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05765913 0,07995843 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05765913 0,07991237 ! steroid catabolic process GO:0006706 31 17 0,000 0,05765913 0,07986636 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05765913 0,07982041 ! gas transport GO:0015669 25 17 0,000 0,05765913 0,07977451 ! organic cation transport GO:0015695 31 17 0,000 0,05765913 0,07972866 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05765913 0,07968287 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05765913 0,07963712 ! microspike assembly GO:0030035 36 17 0,000 0,05765913 0,07959144 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05765913 0,0795458 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05765913 0,07950021 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06094637 0,08398451 ! neuron maturation GO:0042551 42 18 0,000 0,06094637 0,08393644 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06094637 0,08388842 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06094637 0,08384046 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06094637 0,08379255 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06094637 0,08374469 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06094637 0,0836969 ! memory GO:0007613 31 18 0,000 0,06094637 0,08364915 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06094637 0,08360146 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06094637 0,08355382 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06094637 0,08350624 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06094637 0,08345871 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06094637 0,08341124 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06094637 0,08336382 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06094637 0,08331645 ! response to fungus GO:0009620 21 18 0,000 0,06094637 0,08326914 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06094637 0,08322188 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06094637 0,08317468 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06094637 0,08312753 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06094637 0,08308043 ! vitamin transport GO:0051180 27 18 0,000 0,06094637 0,08303339 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06094637 0,0829864 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06094637 0,08293946 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06094637 0,08289257 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06094637 0,08284574 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,06094637 0,08279896 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06094637 0,08275224 ! protein secretion GO:0009306 39 19 0,000 0,06422224 0,087151 ! positive regulation of translation GO:0045727 30 19 0,000 0,06422224 0,08710187 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06422224 0,0870528 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06422224 0,08700378 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06422224 0,08695482 ! skin development GO:0043588 36 19 0,000 0,06422224 0,08690592 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06422224 0,08685707 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06422224 0,08680827 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06422224 0,08675953 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06422224 0,08671084 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06422224 0,08666221 ! cerebral cortex development GO:0021987 36 19 0,000 0,06422224 0,08661363 ! heme metabolic process GO:0042168 36 19 0,000 0,06422224 0,08656511 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06422224 0,08651664 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06422224 0,08646823 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06422224 0,08641987 ! peptide cross-linking GO:0018149 37 19 0,000 0,06422224 0,08637156 ! protein export from nucleus GO:0006611 36 19 0,000 0,06422224 0,08632331 ! heart process GO:0003015 30 19 0,000 0,06422224 0,08627511 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06422224 0,08622697 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06422224 0,08617887 ! visual learning GO:0008542 36 19 0,000 0,06422224 0,08613084 ! cellular pigmentation GO:0033059 36 19 0,000 0,06422224 0,08608285 ! G1 phase GO:0051318 40 19 0,000 0,06422224 0,08603492 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06422224 0,08598705 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06422224 0,08593922 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06422224 0,08589145 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06422224 0,08584373 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06422224 0,08579607 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06422224 0,08574846 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06422224 0,0857009 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06422224 0,08565339 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06422224 0,08560594 ! cilium assembly GO:0042384 37 19 0,000 0,06422224 0,08555854 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06422224 0,08551119 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0674868 0,08980821 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0674868 0,08975857 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0674868 0,08970898 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0674868 0,08965944 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0674868 0,08960996 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0674868 0,08956053 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,0674868 0,08951116 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0674868 0,08946184 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0674868 0,08941258 ! response to alkaloid GO:0043279 38 20 0,000 0,0674868 0,08936337 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0674868 0,08931422 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0674868 0,08926512 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0674868 0,08921607 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0674868 0,08916708 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0674868 0,08911814 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,0674868 0,08906925 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0674868 0,08902042 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0674868 0,08897164 ! body fluid secretion GO:0007589 31 20 0,000 0,0674868 0,08892292 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0674868 0,08887425 ! peptide secretion GO:0002790 35 20 0,000 0,0674868 0,08882563 ! stem cell differentiation GO:0048863 53 20 0,000 0,0674868 0,08877706 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0674868 0,08872855 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0674868 0,08868009 ! sensory perception of pain GO:0019233 30 20 0,000 0,0674868 0,08863169 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0674868 0,08858333 ! diencephalon development GO:0021536 34 20 0,000 0,0674868 0,08853503 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0674868 0,08848678 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0674868 0,08843859 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0674868 0,08839045 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0674868 0,08834235 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0674868 0,08829432 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0674868 0,08824633 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0674868 0,0881984 ! regulation of glucose import GO:0046324 29 20 0,000 0,0674868 0,08815051 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0674868 0,08810268 ! actin filament-based movement GO:0030048 43 20 0,000 0,0674868 0,08805491 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0674868 0,08800718 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0674868 0,08795951 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0674868 0,08791188 ! negative regulation of translation GO:0017148 29 20 0,000 0,0674868 0,08786431 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0674868 0,08781679 ! regulation of cell killing GO:0031341 42 21 0,000 0,07074008 0,09200034 ! hormone secretion GO:0046879 38 21 0,000 0,07074008 0,09195064 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07074008 0,09190099 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07074008 0,09185139 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07074008 0,09180185 ! axis specification GO:0009798 38 21 0,000 0,07074008 0,09175236 ! ovarian follicle development GO:0001541 35 21 0,000 0,07074008 0,09170293 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07074008 0,09165354 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07074008 0,09160422 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07074008 0,09155494 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,07074008 0,09150572 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07074008 0,09145655 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07074008 0,09140743 ! cytolysis GO:0019835 24 21 0,000 0,07074008 0,09135836 ! vasodilation GO:0042311 39 21 0,000 0,07074008 0,09130935 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07074008 0,09126039 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07074008 0,09121149 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07074008 0,09116263 ! DNA modification GO:0006304 34 21 0,000 0,07074008 0,09111383 ! collagen fibril organization GO:0030199 59 21 0,000 0,07074008 0,09106508 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07074008 0,09101638 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07074008 0,09096774 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07074008 0,09091914 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07074008 0,0908706 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07074008 0,09082211 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07074008 0,09077367 ! collagen catabolic process GO:0030574 28 21 0,000 0,07074008 0,09072528 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07074008 0,09067695 ! gut development GO:0048565 39 21 0,000 0,07074008 0,09062866 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07398212 0,09473176 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07398212 0,09468137 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07398212 0,09463103 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07398212 0,09458075 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07398212 0,09453052 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07398212 0,09448034 ! regeneration GO:0031099 41 22 0,000 0,07398212 0,09443022 ! keratinization GO:0031424 28 22 0,000 0,07398212 0,09438015 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07398212 0,09433014 ! sensory perception of taste GO:0050909 28 22 0,000 0,07398212 0,09428017 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,07398212 0,09423026 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07398212 0,09418041 ! vacuolar transport GO:0007034 36 22 0,000 0,07398212 0,0941306 ! lysosome organization GO:0007040 41 22 0,000 0,07398212 0,09408085 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07398212 0,09403115 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07398212 0,0939815 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07398212 0,09393191 ! fucose metabolic process GO:0006004 39 22 0,000 0,07398212 0,09388237 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07398212 0,09383288 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07398212 0,09378344 ! ureteric bud development GO:0001657 43 22 0,000 0,07398212 0,09373405 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07398212 0,09368472 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,07398212 0,09363544 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07398212 0,09358621 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07398212 0,09353703 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07398212 0,0934879 ! sarcomere organization GO:0045214 30 22 0,000 0,07398212 0,09343883 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,07398212 0,09338981 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07398212 0,09334083 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07398212 0,09329191 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07398212 0,09324304 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,07721295 0,09726406 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07721295 0,09721316 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,07721295 0,09716232 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07721295 0,09711153 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07721295 0,09706079 ! gluconeogenesis GO:0006094 33 23 0,000 0,07721295 0,0970101 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07721295 0,09695947 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07721295 0,09690889 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07721295 0,09685837 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07721295 0,09680789 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07721295 0,09675747 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07721295 0,09670711 ! visual behavior GO:0007632 42 23 0,000 0,07721295 0,09665679 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,07721295 0,09660653 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07721295 0,09655632 ! response to ethanol GO:0045471 46 23 0,000 0,07721295 0,09650616 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07721295 0,09645605 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07721295 0,09640599 ! peroxisome organization GO:0007031 37 23 0,000 0,07721295 0,09635599 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07721295 0,09630604 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07721295 0,09625614 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07721295 0,09620629 ! sex determination GO:0007530 47 23 0,000 0,07721295 0,0961565 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07721295 0,09610675 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07721295 0,09605706 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07721295 0,09600742 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07721295 0,09595783 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07721295 0,09590829 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07721295 0,0958588 ! fatty acid transport GO:0015908 44 23 0,000 0,07721295 0,09580936 ! platelet activation GO:0030168 37 23 0,000 0,07721295 0,09575997 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07721295 0,09571064 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07721295 0,09566135 ! hormone transport GO:0009914 40 23 0,000 0,07721295 0,09561212 ! cell-cell recognition GO:0009988 25 23 0,000 0,07721295 0,09556294 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07721295 0,0955138 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07721295 0,09546472 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07721295 0,09541569 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07721295 0,09536671 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,08043261 0,09929239 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08043261 0,09924147 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,08043261 0,0991906 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,08043261 0,09913979 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08043261 0,09908903 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,08043261 0,09903832 ! vesicle docking GO:0048278 47 24 0,000 0,08043261 0,09898766 ! spinal cord development GO:0021510 47 24 0,000 0,08043261 0,09893705 ! vacuole organization GO:0007033 43 24 0,000 0,08043261 0,09888649 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08043261 0,09883599 ! digestive system process GO:0022600 39 24 0,000 0,08043261 0,09878554 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08043261 0,09873514 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08043261 0,09868479 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,08043261 0,09863449 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,08043261 0,09858424 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08043261 0,09853405 ! membrane depolarization GO:0051899 39 24 0,000 0,08043261 0,0984839 ! pentose metabolic process GO:0019321 35 24 0,000 0,08043261 0,09843381 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,08043261 0,09838377 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,08043261 0,09833377 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08043261 0,09828383 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08043261 0,09823394 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08043261 0,0981841 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08043261 0,09813431 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08043261 0,09808458 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08043261 0,09803489 ! regulation of amine transport GO:0051952 40 24 0,000 0,08043261 0,09798525 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,08364115 0,10184242 ! myelination GO:0042552 45 25 0,000 0,08364115 0,1017909 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08364115 0,10173944 ! phototransduction GO:0007602 33 25 0,000 0,08364115 0,10168803 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08364115 0,10163667 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,08364115 0,10158537 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,08364115 0,10153411 ! chromosome condensation GO:0030261 45 25 0,000 0,08364115 0,10148291 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08364115 0,10143176 ! neural crest cell development GO:0014032 54 25 0,000 0,08364115 0,10138066 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08364115 0,10132961 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,08364115 0,10127862 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08364115 0,10122767 ! interaction with host GO:0051701 62 25 0,000 0,08364115 0,10117678 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08364115 0,10112594 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,08364115 0,10107514 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08364115 0,1010244 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,08364115 0,10097371 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08364115 0,10092308 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08364115 0,10087249 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,08364115 0,10082195 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08364115 0,10077146 ! telomere organization GO:0032200 43 25 0,000 0,08364115 0,10072103 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,08364115 0,10067064 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0868386 0,10446684 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0868386 0,10441463 ! initiation of viral infection GO:0019059 57 26 0,000 0,0868386 0,10436248 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0868386 0,10431037 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0868386 0,10425832 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0868386 0,10420632 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0868386 0,10415438 ! molting cycle process GO:0022404 50 26 0,000 0,0868386 0,10410248 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0868386 0,10405064 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0868386 0,10399884 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0868386 0,1039471 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0868386 0,10389541 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0868386 0,10384378 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0868386 0,10379219 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0868386 0,10374066 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0868386 0,10368917 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0868386 0,10363774 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,0868386 0,10358636 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0868386 0,10353502 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0868386 0,10348374 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0868386 0,10343251 ! neuron fate commitment GO:0048663 48 27 0,000 0,090025 0,10717474 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,090025 0,10712174 ! iron ion transport GO:0006826 59 27 0,000 0,090025 0,10706879 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,090025 0,10701589 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,090025 0,10696304 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,090025 0,10691025 ! fat cell differentiation GO:0045444 50 27 0,000 0,090025 0,1068575 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,090025 0,10680481 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,090025 0,10675217 ! autophagy GO:0006914 41 27 0,000 0,090025 0,10669958 ! male gonad development GO:0008584 44 27 0,000 0,090025 0,10664705 ! response to toxin GO:0009636 47 27 0,000 0,090025 0,10659457 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,090025 0,10654213 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,090025 0,10648975 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,090025 0,10643742 ! glutathione metabolic process GO:0006749 39 27 0,000 0,090025 0,10638515 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,090025 0,10633292 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,090025 0,10628074 ! circadian rhythm GO:0007623 50 28 0,000 0,09320039 0,10997554 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,09320039 0,10992164 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,09320039 0,10986778 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,09320039 0,10981397 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,09320039 0,10976022 ! synaptogenesis GO:0007416 42 28 0,000 0,09320039 0,10970652 ! lipid oxidation GO:0034440 43 28 0,000 0,09320039 0,10965288 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,09320039 0,10959928 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,09320039 0,10954574 ! translational initiation GO:0006413 65 29 0,000 0,0963648 0,11320982 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0963648 0,11315457 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0963648 0,11309937 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0963648 0,11304423 ! catechol metabolic process GO:0009712 54 29 0,000 0,0963648 0,11298914 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0963648 0,1129341 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0963648 0,11287912 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0963648 0,11282419 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0963648 0,11276931 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0963648 0,11271449 ! cell fate determination GO:0001709 60 29 0,000 0,0963648 0,11265972 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0963648 0,11260501 ! detection of light stimulus GO:0009583 38 29 0,000 0,0963648 0,11255034 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0963648 0,11249573 ! regulation of coagulation GO:0050818 46 29 0,000 0,0963648 0,11244118 ! phenol metabolic process GO:0018958 55 30 0,000 0,09951827 0,11606445 ! zinc ion transport GO:0006829 45 30 0,000 0,09951827 0,11600822 ! membrane docking GO:0022406 61 30 0,000 0,09951827 0,11595204 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09951827 0,11589592 ! cell junction assembly GO:0034329 78 30 0,000 0,09951827 0,11583985 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09951827 0,11578383 ! acute-phase response GO:0006953 49 30 0,000 0,09951827 0,11572787 ! myofibril assembly GO:0030239 47 30 0,000 0,09951827 0,11567196 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09951827 0,11561611 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09951827 0,11556031 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09951827 0,11550457 ! phospholipid transport GO:0015914 51 30 0,000 0,09951827 0,11544887 ! ensheathment of neurons GO:0007272 57 30 0,000 0,09951827 0,11539324 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09951827 0,11533765 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,09951827 0,11528212 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09951827 0,11522664 ! eye morphogenesis GO:0048592 60 30 0,000 0,09951827 0,11517122 ! regulation of B cell activation GO:0050864 50 30 0,000 0,09951827 0,11511585 ! response to heat GO:0009408 50 30 0,000 0,09951827 0,11506053 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,10266085 0,11863688 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,10266085 0,11857993 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,10266085 0,11852303 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,10266085 0,11846618 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,10266085 0,11840939 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,10266085 0,11835266 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,10266085 0,11829597 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,10266085 0,11823935 ! ovulation cycle process GO:0022602 49 31 0,000 0,10266085 0,11818277 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,10266085 0,11812625 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,10266085 0,11806979 ! peptide transport GO:0015833 55 31 0,000 0,10266085 0,11801338 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,10266085 0,11795702 ! iron ion homeostasis GO:0055072 54 31 0,000 0,10266085 0,11790071 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,10266085 0,11784446 ! mesoderm formation GO:0001707 69 31 0,000 0,10266085 0,11778827 ! natural killer cell activation GO:0030101 45 31 0,000 0,10266085 0,11773212 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,10266085 0,11767603 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,10266085 0,11762 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,10266085 0,11756401 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,10579255 0,12109272 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10579255 0,12103513 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10579255 0,12097761 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10579255 0,12092014 ! cholesterol transport GO:0030301 56 32 0,000 0,10579255 0,12086272 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10579255 0,12080536 ! spliceosome assembly GO:0000245 67 32 0,000 0,10579255 0,12074805 ! spindle organization GO:0007051 46 32 0,000 0,10579255 0,1206908 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10579255 0,1206336 ! metanephros development GO:0001656 74 32 0,000 0,10579255 0,12057645 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,10579255 0,12051936 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,10579255 0,12046232 ! muscle cell development GO:0055001 49 32 0,000 0,10579255 0,12040534 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10579255 0,12034841 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10579255 0,12029153 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10579255 0,12023471 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,10579255 0,12017794 ! ovulation cycle GO:0042698 51 32 0,000 0,10579255 0,12012123 ! peripheral nervous system development GO:0007422 64 32 0,000 0,10579255 0,12006457 ! BMP signaling pathway GO:0030509 64 32 0,000 0,10579255 0,12000796 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10579255 0,11995141 ! gene silencing GO:0016458 65 32 0,000 0,10579255 0,11989491 ! post-embryonic development GO:0009791 69 33 0,000 0,10891344 0,1233737 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10891344 0,12331564 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10891344 0,12325764 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10891344 0,12319969 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10891344 0,12314179 ! cell fate specification GO:0001708 52 33 0,000 0,10891344 0,12308395 ! sterol transport GO:0015918 57 33 0,000 0,10891344 0,12302617 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10891344 0,12296843 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 0,000 0,10891344 0,12291076 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10891344 0,12285313 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,11202353 0,12630207 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,11202353 0,12624291 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,11202353 0,12618381 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,11202353 0,12612476 ! mismatch repair GO:0006298 46 34 0,000 0,11202353 0,12606577 ! spermatid development GO:0007286 63 34 0,000 0,11202353 0,12600684 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,11202353 0,12594795 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,11202353 0,12588913 ! placenta development GO:0001890 53 34 0,000 0,11202353 0,12583036 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,11202353 0,12577164 ! negative regulation of secretion GO:0051048 63 35 0,000 0,11512288 0,12919106 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,11512288 0,12913083 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,11512288 0,12907066 ! odontogenesis GO:0042476 66 35 0,000 0,11512288 0,12901054 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,11512288 0,12895048 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 0,000 0,11512288 0,12889048 ! cytokine production GO:0001816 59 35 0,000 0,11512288 0,12883053 ! vesicle localization GO:0051648 64 35 0,000 0,11512288 0,12877064 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1182115 0,13216398 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,1182115 0,13210259 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1182115 0,13204126 ! cell junction organization GO:0034330 86 36 0,000 0,1182115 0,13197999 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1182115 0,13191877 ! positive regulation of cell development GO:0010720 80 36 0,000 0,1182115 0,13185762 ! regulation of proteolysis GO:0030162 72 36 0,000 0,1182115 0,13179651 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1182115 0,13173547 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1182115 0,13167448 ! aerobic respiration GO:0009060 55 36 0,000 0,1182115 0,13161355 ! embryonic organ development GO:0048568 57 36 0,000 0,1182115 0,13155267 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1182115 0,13149185 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,1182115 0,13143109 ! RNA export from nucleus GO:0006405 56 37 0,000 0,12128945 0,13479096 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,12128945 0,13472873 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,12128945 0,13466655 ! sister chromatid segregation GO:0000819 58 37 0,000 0,12128945 0,13460444 ! actomyosin structure organization GO:0031032 62 37 0,000 0,12128945 0,13454238 ! organic anion transport GO:0015711 68 37 0,000 0,12128945 0,13448038 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,12128945 0,13441844 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,12128945 0,13435655 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,12128945 0,13429472 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,12128945 0,13423295 ! spermatid differentiation GO:0048515 66 37 0,000 0,12128945 0,13417123 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,12435676 0,13750109 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,12435676 0,13743793 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,12435676 0,13737482 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,12435676 0,13731178 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,12435676 0,13724879 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 0,000 0,12435676 0,13718586 ! lipid homeostasis GO:0055088 67 38 0,000 0,12435676 0,13712299 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,12435676 0,13706018 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,12435676 0,13699742 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,12435676 0,13693472 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,12435676 0,13687208 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 0,000 0,12741346 0,14017229 ! learning GO:0007612 77 39 0,000 0,12741346 0,14010822 ! ear morphogenesis GO:0042471 60 39 0,000 0,12741346 0,14004422 ! organic ether metabolic process GO:0018904 55 39 0,000 0,12741346 0,13998027 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12741346 0,13991638 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12741346 0,13985255 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,12741346 0,13978878 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,12741346 0,13972506 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,12741346 0,13966141 ! RNA modification GO:0009451 57 39 0,000 0,12741346 0,13959781 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,1304596 0,14287018 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,1304596 0,14280518 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,1304596 0,14274024 ! feeding behavior GO:0007631 59 40 0,000 0,1304596 0,14267536 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,1304596 0,14261053 ! mesenchymal cell development GO:0014031 87 40 0,000 0,1304596 0,14254577 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,1304596 0,14248107 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1334952 0,14573024 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1334952 0,14566415 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1334952 0,14559811 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1334952 0,14553214 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,1334952 0,14546623 ! polyol metabolic process GO:0019751 66 41 0,000 0,1334952 0,14540038 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1365203 0,14862798 ! regulation of tube size GO:0035150 71 42 0,000 0,1365203 0,14856076 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1365203 0,1484936 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1365203 0,1484265 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1365203 0,14835946 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1365203 0,14829248 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,1365203 0,14822556 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,13953494 0,15143034 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,13953494 0,15136207 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,13953494 0,15129386 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,13953494 0,15122571 ! glucose transport GO:0015758 65 43 0,000 0,13953494 0,15115762 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,13953494 0,15108959 ! striated muscle contraction GO:0006941 77 43 0,000 0,13953494 0,15102162 ! phagocytosis GO:0006909 90 43 0,000 0,13953494 0,15095372 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,13953494 0,15088587 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,14253916 0,15406524 ! hexose transport GO:0008645 67 44 0,000 0,14253916 0,15399606 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,14253916 0,15392694 ! male sex differentiation GO:0046661 76 44 0,000 0,14253916 0,15385788 ! biopolymer methylation GO:0043414 84 44 0,000 0,14253916 0,15378889 ! glycolysis GO:0006096 65 45 0,000 0,14553299 0,15694862 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,14553299 0,1568783 ! leukocyte migration GO:0050900 68 45 0,000 0,14553299 0,15680805 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,14553299 0,15673785 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,14553299 0,15666772 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,14553299 0,15659766 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,14553299 0,15652766 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,14851646 0,15966515 ! positive regulation of defense response GO:0031349 76 47 0,000 0,15148962 0,16278875 ! response to calcium ion GO:0051592 81 47 0,000 0,15148962 0,16271608 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,15148962 0,16264347 ! JNK cascade GO:0007254 91 47 0,000 0,15148962 0,16257093 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,15148962 0,16249845 ! methylation GO:0032259 90 47 0,000 0,15148962 0,16242603 ! Notch signaling pathway GO:0007219 96 48 0,000 0,15445249 0,16552904 ! cellular component disassembly GO:0022411 86 48 0,000 0,15445249 0,16545534 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,15445249 0,1653817 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,15445249 0,16530814 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,15445249 0,16523463 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,15445249 0,1651612 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,15445249 0,16508782 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,15740511 0,16816905 ! regulation of action potential GO:0001508 95 49 0,000 0,15740511 0,16809441 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,15740511 0,16801983 ! regulation of ion transport GO:0043269 77 49 0,000 0,15740511 0,16794532 ! peptide metabolic process GO:0006518 76 49 0,000 0,15740511 0,16787088 ! response to temperature stimulus GO:0009266 76 49 0,000 0,15740511 0,1677965 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,15740511 0,16772219 ! endocrine system development GO:0035270 104 49 0,000 0,15740511 0,16764794 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,15740511 0,16757376 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,15740511 0,16749965 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,15740511 0,1674256 ! neuromuscular process GO:0050905 99 50 0,000 0,16034753 0,17047996 ! regulation of ossification GO:0030278 117 50 0,000 0,16034753 0,17040466 ! inner ear development GO:0048839 79 50 0,000 0,16034753 0,17032943 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,16034753 0,17025426 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,16034753 0,17017916 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,16034753 0,17010412 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,16327976 0,17313843 ! excretion GO:0007588 83 51 0,000 0,16327976 0,17306216 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,16327976 0,17298596 ! vesicle organization GO:0016050 107 51 0,000 0,16327976 0,17290982 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,16327976 0,17283375 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 0,000 0,16620185 0,17584946 ! positive regulation of growth GO:0045927 90 52 0,000 0,16620185 0,17577216 ! cartilage development GO:0051216 90 52 0,000 0,16620185 0,17569493 ! synapse organization GO:0050808 85 52 0,000 0,16620185 0,17561777 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,16911384 0,17861628 ! RNA catabolic process GO:0006401 93 53 0,000 0,16911384 0,17853791 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,16911384 0,1784596 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,16911384 0,17838137 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,17201575 0,18136279 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,17201575 0,18128335 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,17201575 0,18120398 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,17201575 0,18112468 ! chloride transport GO:0006821 90 55 0,000 0,17490762 0,18408912 ! glucose catabolic process GO:0006007 82 55 0,000 0,17490762 0,18400863 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,17490762 0,18392821 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,17490762 0,18384785 ! gastrulation GO:0007369 112 55 0,000 0,17490762 0,18376757 ! heart morphogenesis GO:0003007 97 55 0,000 0,17490762 0,18368736 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,17490762 0,18360722 ! RNA elongation GO:0006354 79 55 0,000 0,17490762 0,18352714 ! nuclear export GO:0051168 97 55 0,000 0,17490762 0,18344714 ! sensory perception of smell GO:0007608 80 56 0,000 0,17778949 0,18638846 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,17778949 0,18630728 ! proton transport GO:0015992 94 56 0,000 0,17778949 0,18622617 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,17778949 0,18614513 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,18066139 0,18906972 ! hydrogen transport GO:0006818 97 58 0,000 0,18352335 0,19198138 ! regulation of endocytosis GO:0030100 91 58 0,000 0,18352335 0,19189795 ! adult behavior GO:0030534 99 58 0,000 0,18352335 0,19181458 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,18352335 0,1917313 ! positive regulation of secretion GO:0051047 95 59 0,000 0,18637541 0,1946264 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,18637541 0,19454196 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,18637541 0,1944576 ! establishment of organelle localization GO:0051656 109 59 0,000 0,18637541 0,19437331 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1892176 0,19725197 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1892176 0,19716654 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1892176 0,19708119 ! camera-type eye development GO:0043010 116 60 0,000 0,1892176 0,19699591 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1892176 0,1969107 ! kidney development GO:0001822 122 60 0,000 0,1892176 0,19682557 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,19204995 0,19968548 ! tRNA processing GO:0008033 89 61 0,000 0,19204995 0,19959922 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,19204995 0,19951304 ! ear development GO:0043583 103 62 0,000 0,19487251 0,2023579 ! regulation of mitosis GO:0007088 105 63 0,000 0,1976853 0,20519018 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1976853 0,2051017 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,1976853 0,20501329 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,20048836 0,20783067 ! cell redox homeostasis GO:0045454 102 64 0,000 0,20048836 0,20774117 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,20048836 0,20765174 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,20048836 0,20756239 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,20048836 0,20747311 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,20328171 0,21027334 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,20328171 0,21018298 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,2060654 0,21296965 ! extracellular matrix organization GO:0030198 133 66 0,000 0,2060654 0,21287821 ! cell projection assembly GO:0030031 120 66 0,000 0,2060654 0,21278685 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,20883946 0,21555887 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,20883946 0,21546644 ! activation of MAPK activity GO:0000187 115 67 0,000 0,20883946 0,21537408 ! chromosome segregation GO:0007059 113 67 0,000 0,20883946 0,2152818 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,20883946 0,21518961 ! hexose catabolic process GO:0019320 104 67 0,000 0,20883946 0,21509749 ! activation of immune response GO:0002253 105 67 0,000 0,20883946 0,21500545 ! amino acid transport GO:0006865 125 68 0,000 0,21160391 0,21775834 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,21160391 0,21766525 ! regulation of lipase activity GO:0060191 130 68 0,000 0,21160391 0,21757223 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,21160391 0,21747929 ! urogenital system development GO:0001655 137 69 0,000 0,2143588 0,2202166 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2143588 0,22012261 ! humoral immune response GO:0006959 109 71 0,000 0,21984 0,22565488 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,21984 0,22555865 ! regulation of immune effector process GO:0002697 137 71 0,000 0,21984 0,2254625 ! acute inflammatory response GO:0002526 113 72 0,000 0,22256638 0,22816136 ! carbohydrate transport GO:0008643 110 72 0,000 0,22256638 0,22806418 ! regulation of blood pressure GO:0008217 125 73 0,000 0,22528332 0,23074997 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,22528332 0,23065177 ! fertilization GO:0009566 90 73 0,000 0,22528332 0,23055367 ! transition metal ion transport GO:0000041 126 74 0,000 0,22799086 0,23322534 ! neurotransmitter transport GO:0006836 123 74 0,000 0,22799086 0,23312622 ! exocytosis GO:0006887 133 74 0,000 0,22799086 0,23302719 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,22799086 0,23292824 ! eye development GO:0001654 143 74 0,000 0,22799086 0,23282937 ! organelle localization GO:0051640 136 74 0,000 0,22799086 0,23273059 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,23068902 0,23538498 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,23068902 0,2352852 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,23068902 0,2351855 ! rhythmic process GO:0048511 128 75 0,000 0,23068902 0,23508589 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,23337785 0,23772527 ! defense response to bacterium GO:0042742 89 76 0,000 0,23337785 0,23762467 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,23337785 0,23752415 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,23605736 0,24014969 ! blood coagulation GO:0007596 146 78 0,000 0,2387276 0,24276357 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,2387276 0,24266101 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,24138859 0,24526223 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,24138859 0,2451587 ! response to metal ion GO:0010038 140 80 0,000 0,24404038 0,24774732 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,24404038 0,24764283 ! inorganic anion transport GO:0015698 138 80 0,000 0,24404038 0,24753843 ! digestion GO:0007586 112 81 0,000 0,24668298 0,25011346 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,24931642 0,25267705 ! hemostasis GO:0007599 158 84 0,000 0,254556 0,25787862 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,254556 0,25777009 ! nucleosome assembly GO:0006334 122 85 0,000 0,25716219 0,26029963 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,25716219 0,26019017 ! amine biosynthetic process GO:0009309 138 86 0,000 0,25975935 0,26270744 ! response to inorganic substance GO:0010035 153 86 0,000 0,25975935 0,26259706 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,25975935 0,26248677 ! chromatin assembly GO:0031497 124 86 0,000 0,25975935 0,26237657 ! alcohol catabolic process GO:0046164 130 86 0,000 0,25975935 0,26226647 ! amine transport GO:0015837 155 86 0,000 0,25975935 0,26215646 ! cellular respiration GO:0045333 135 88 0,000 0,26492672 0,26725941 ! regulation of neurological system process GO:0031644 148 88 0,000 0,26492672 0,2671474 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,26492672 0,26703548 ! cellular defense response GO:0006968 114 89 0,000 0,26749699 0,2695133 ! ossification GO:0001503 188 90 0,000 0,27005836 0,27198008 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,27005836 0,27186628 ! bone development GO:0060348 189 91 0,000 0,27261086 0,27432109 ! sterol metabolic process GO:0016125 152 91 0,000 0,27261086 0,27420641 ! regulation of defense response GO:0031347 149 92 0,000 0,27515452 0,2766493 ! nucleosome organization GO:0034728 138 92 0,000 0,27515452 0,27653374 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,27515452 0,27641828 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,27768937 0,27884834 ! regulation of membrane potential GO:0042391 164 93 0,000 0,27768937 0,278732 ! female pregnancy GO:0007565 164 94 0,000 0,28021543 0,28115026 ! transcription initiation GO:0006352 153 94 0,000 0,28021543 0,28103307 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,28273275 0,28343958 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,28524134 0,28583535 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,28524134 0,28571635 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,28774125 0,28810048 ! hormone metabolic process GO:0042445 157 97 0,000 0,28774125 0,28798063 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,29023249 0,29035317 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,29271511 0,29271511