pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6390-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 86 42 4,000 2,736E-07 6,685E-04 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 2,000 3,459E-07 4,226E-04 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! T cell activation GO:0042110 189 84 5,000 3,685E-07 3,001E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 4,363E-07 2,665E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 3,000 5,186E-07 2,534E-04 ! response to vitamin GO:0033273 36 20 3,000 5,186E-07 2,112E-04 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 2,000 6,902E-07 2,409E-04 ! reciprocal meiotic recombination GO:0007131 44 22 3,000 7,791E-07 2,379E-04 ! positive regulation of intracellular transport GO:0032388 42 22 3,000 7,791E-07 2,115E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 9,193E-07 2,246E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,205E-06 2,676E-04 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 2,000 1,205E-06 2,453E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,295E-06 2,433E-04 ! regulation of intracellular transport GO:0032386 108 57 4,000 1,295E-06 2,26E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 1,337E-06 2,178E-04 ! response to endoplasmic reticulum stress GO:0034976 46 26 3,000 1,576E-06 2,407E-04 ! negative regulation of cell development GO:0010721 83 26 3,000 1,576E-06 2,265E-04 GO:0050768|negative regulation of neurogenesis, ! ER overload response GO:0006983 13 8 2,000 1,923E-06 2,61E-04 ! DNA damage response, signal transduction GO:0042770 136 62 4,000 1,975E-06 2,54E-04 ! ER-nuclear signaling pathway GO:0006984 52 29 3,000 2,485E-06 3,035E-04 ! regulation of T-helper 1 type immune response GO:0002825 12 9 2,000 2,878E-06 3,348E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 4,000 2,909E-06 3,231E-04 ! negative regulation of ligase activity GO:0051352 116 68 4,000 3,132E-06 3,327E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 4,000 3,132E-06 3,188E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 4,000 3,368E-06 3,291E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 4,101E-06 3,854E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 4,000 4,16E-06 3,764E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 4,000 4,16E-06 3,63E-04 ! DNA damage checkpoint GO:0000077 78 35 3,000 5,395E-06 4,545E-04 ! positive regulation of ligase activity GO:0051351 130 77 4,000 5,798E-06 4,722E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 4,000 6,579E-06 5,185E-04 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 6,771E-06 5,169E-04 ! meiosis GO:0007126 143 81 4,000 7,44E-06 5,508E-04 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 2,000 7,483E-06 5,377E-04 ! meiosis I GO:0007127 74 38 3,000 7,548E-06 5,269E-04 ! DNA integrity checkpoint GO:0031570 82 38 3,000 7,548E-06 5,122E-04 ! meiotic cell cycle GO:0051321 144 82 4,000 7,903E-06 5,218E-04 ! response to nutrient GO:0007584 135 84 4,000 8,895E-06 5,719E-04 ! regulation of ligase activity GO:0051340 147 84 4,000 8,895E-06 5,572E-04 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 2,000 9,705E-06 5,927E-04 ! response to X-ray GO:0010165 28 13 2,000 9,705E-06 5,783E-04 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 2,000 9,705E-06 5,645E-04 ! regulation of protein transport GO:0051223 165 87 4,000 1,056E-05 6,001E-04 GO:0070201|regulation of establishment of protein localization, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 2,000 1,232E-05 6,842E-04 ! response to gamma radiation GO:0010332 30 14 2,000 1,232E-05 6,689E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 4,000 1,463E-05 7,767E-04 GO:0010498|proteasomal protein catabolic process, ! positive regulation of protein transport GO:0051222 80 46 3,000 1,635E-05 8,499E-04 ! regulation of protein localization GO:0032880 188 97 4,000 1,795E-05 9,134E-04 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 2,000 1,887E-05 9,406E-04 ! positive regulation of protein import into nucleus GO:0042307 34 16 2,000 1,887E-05 9,218E-04 ! regulation of T-helper cell differentiation GO:0045622 30 16 2,000 1,887E-05 9,037E-04 ! myoblast differentiation GO:0045445 50 17 2,000 2,285E-05 1,074E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 2,000 2,285E-05 1,053E-03 ! centrosome cycle GO:0007098 26 18 2,000 2,736E-05 1,238E-03 ! response to retinoic acid GO:0032526 31 18 2,000 2,736E-05 1,215E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 2,000 2,736E-05 1,194E-03 ! detection of bacterium GO:0016045 22 18 2,000 2,736E-05 1,173E-03 ! response to vitamin A GO:0033189 32 19 2,000 3,241E-05 1,365E-03 ! regulation of interleukin-2 production GO:0032663 39 20 2,000 3,804E-05 1,575E-03 ! phosphatidylinositol metabolic process GO:0046488 47 21 2,000 4,427E-05 1,803E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 2,000 4,427E-05 1,773E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 5,114E-05 2,015E-03 ! cell aging GO:0007569 48 22 2,000 5,114E-05 1,983E-03 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 2,000 5,114E-05 1,952E-03 ! calcium-independent cell-cell adhesion GO:0016338 36 24 2,000 6,689E-05 2,514E-03 ! detection of biotic stimulus GO:0009595 34 24 2,000 6,689E-05 2,476E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 6,865E-05 2,503E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 7,583E-05 2,724E-03 ! vasculogenesis GO:0001570 49 25 2,000 7,583E-05 2,685E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 7,583E-05 2,646E-03 ! negative regulation of DNA replication GO:0008156 45 25 2,000 7,583E-05 2,609E-03 ! regulation of alpha-beta T cell activation GO:0046634 48 25 2,000 7,583E-05 2,573E-03 ! regulation of transcription factor import into nucleus GO:0042990 58 26 2,000 8,551E-05 2,862E-03 ! microtubule organizing center organization GO:0031023 42 26 2,000 8,551E-05 2,823E-03 GO:0051297|centrosome organization, ! cell cycle checkpoint GO:0000075 145 71 3,000 9,138E-05 2,977E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 9,138E-05 2,937E-03 ! benzene and derivative metabolic process GO:0042537 12 5 1,000 1,067E-04 3,386E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,067E-04 3,343E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,067E-04 3,301E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,067E-04 3,259E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 1,067E-04 3,219E-03 ! virus-infected cell apoptosis GO:0006926 7 5 1,000 1,067E-04 3,18E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,067E-04 3,142E-03 ! indolalkylamine catabolic process GO:0046218 8 5 1,000 1,067E-04 3,104E-03 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,067E-04 3,068E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,067E-04 3,032E-03 ! positive regulation of T cell differentiation GO:0045582 48 28 2,000 1,072E-04 3,011E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 1,074E-04 2,981E-03 ! cell-matrix adhesion GO:0007160 181 76 3,000 1,191E-04 3,27E-03 ! phosphoinositide metabolic process GO:0030384 146 77 3,000 1,254E-04 3,403E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 1,254E-04 3,365E-03 ! steroid biosynthetic process GO:0006694 146 79 3,000 1,385E-04 3,677E-03 ! response to interferon-gamma GO:0034341 16 6 1,000 1,598E-04 4,197E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 1,598E-04 4,152E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,598E-04 4,108E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,598E-04 4,066E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 1,000 1,598E-04 4,024E-03 ! response to UV-C GO:0010225 14 6 1,000 1,598E-04 3,983E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,598E-04 3,942E-03 ! negative regulation of axon extension GO:0030517 24 6 1,000 1,598E-04 3,903E-03 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 1,598E-04 3,864E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 1,6E-04 3,832E-03 ! cell-substrate adhesion GO:0031589 189 82 3,000 1,6E-04 3,794E-03 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 1,608E-04 3,777E-03 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 2,000 1,608E-04 3,741E-03 ! response to ionizing radiation GO:0010212 74 33 2,000 1,765E-04 4,067E-03 ! negative regulation of protein transport GO:0051224 74 33 2,000 1,765E-04 4,029E-03 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 2,107E-04 4,765E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 2,232E-04 5,002E-03 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 2,232E-04 4,957E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 2,232E-04 4,912E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,232E-04 4,868E-03 GO:0043489|RNA stabilization, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 2,232E-04 4,825E-03 ! tryptophan metabolic process GO:0006568 11 7 1,000 2,232E-04 4,783E-03 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 2,232E-04 4,741E-03 ! centrosome duplication GO:0051298 14 7 1,000 2,232E-04 4,7E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 2,232E-04 4,66E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,232E-04 4,621E-03 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 2,232E-04 4,582E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,232E-04 4,544E-03 ! axonal fasciculation GO:0007413 19 7 1,000 2,232E-04 4,506E-03 ! male meiosis GO:0007140 9 8 1,000 2,969E-04 5,946E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,969E-04 5,898E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,969E-04 5,85E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,969E-04 5,803E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 2,969E-04 5,757E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,969E-04 5,712E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2,969E-04 5,667E-03 ! response to tumor cell GO:0002347 16 8 1,000 2,969E-04 5,623E-03 ! blastocyst growth GO:0001832 19 8 1,000 2,969E-04 5,58E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,969E-04 5,537E-03 ! NAD biosynthetic process GO:0009435 17 8 1,000 2,969E-04 5,496E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 3,427E-04 6,295E-03 GO:0060538|skeletal muscle organ development, ! T cell differentiation GO:0030217 93 42 2,000 3,634E-04 6,625E-03 ! regulation of T cell differentiation GO:0045580 78 42 2,000 3,634E-04 6,575E-03 ! induction of positive chemotaxis GO:0050930 17 9 1,000 3,809E-04 6,843E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 3,809E-04 6,793E-03 ! glycine catabolic process GO:0006546 15 9 1,000 3,809E-04 6,744E-03 ! receptor clustering GO:0043113 20 9 1,000 3,809E-04 6,695E-03 ! double-strand break repair GO:0006302 85 44 2,000 4,172E-04 7,28E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 4,459E-04 7,726E-03 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 2,000 4,459E-04 7,672E-03 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 4,752E-04 8,118E-03 ! lung alveolus development GO:0048286 26 10 1,000 4,752E-04 8,061E-03 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 4,752E-04 8,006E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 4,752E-04 7,951E-03 ! multicellular organism growth GO:0035264 19 10 1,000 4,752E-04 7,897E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 4,752E-04 7,843E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 4,752E-04 7,791E-03 GO:0045685|regulation of glial cell differentiation, ! serine family amino acid catabolic process GO:0009071 18 10 1,000 4,752E-04 7,739E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 1,000 4,752E-04 7,688E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 4,752E-04 7,637E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 4,759E-04 7,599E-03 ! negative regulation of cell migration GO:0030336 122 46 2,000 4,759E-04 7,549E-03 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 2,000 4,759E-04 7,501E-03 ! cell growth GO:0016049 90 46 2,000 4,759E-04 7,453E-03 ! regulation of adaptive immune response GO:0002819 92 48 2,000 5,396E-04 8,397E-03 ! JAK-STAT cascade GO:0007259 82 48 2,000 5,396E-04 8,344E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 5,735E-04 8,811E-03 ! negative regulation of muscle development GO:0048635 27 11 1,000 5,795E-04 8,848E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 5,795E-04 8,793E-03 ! blood vessel remodeling GO:0001974 30 11 1,000 5,795E-04 8,739E-03 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 5,795E-04 8,685E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 5,795E-04 8,632E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 5,795E-04 8,58E-03 ! negative regulation of axonogenesis GO:0050771 37 11 1,000 5,795E-04 8,528E-03 ! neuroblast proliferation GO:0007405 25 11 1,000 5,795E-04 8,477E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 5,795E-04 8,427E-03 ! oocyte development GO:0048599 20 11 1,000 5,795E-04 8,377E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 5,795E-04 8,328E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 6,086E-04 8,695E-03 ! activation of caspase activity GO:0006919 95 50 2,000 6,086E-04 8,644E-03 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 6,939E-04 9,799E-03 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 6,939E-04 9,743E-03 ! hippocampus development GO:0021766 29 12 1,000 6,939E-04 9,687E-03 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 6,939E-04 9,632E-03 ! cranial nerve development GO:0021545 23 12 1,000 6,939E-04 9,577E-03 ! histone acetylation GO:0016573 27 12 1,000 6,939E-04 9,524E-03 ! autonomic nervous system development GO:0048483 24 12 1,000 6,939E-04 9,47E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,939E-04 9,418E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 6,939E-04 9,366E-03 ! oocyte differentiation GO:0009994 21 12 1,000 6,939E-04 9,314E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 6,939E-04 9,263E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 7,222E-04 9,589E-03 ! regulation of angiogenesis GO:0045765 125 54 2,000 7,629E-04 0,01007378 ! response to UV GO:0009411 120 55 2,000 8,049E-04 0,01057236 ! negative regulation of cell motion GO:0051271 142 55 2,000 8,049E-04 0,01051582 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 8,183E-04 0,01063361 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 8,183E-04 0,01057734 GO:0000725|recombinational repair, ! indolalkylamine metabolic process GO:0006586 19 13 1,000 8,183E-04 0,01052167 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 8,183E-04 0,01046659 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 1,000 8,183E-04 0,01041207 ! regulation of mRNA stability GO:0043488 32 13 1,000 8,183E-04 0,01035812 ! biogenic amine catabolic process GO:0042402 24 13 1,000 8,183E-04 0,01030473 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 8,183E-04 0,01025189 ! skeletal muscle fiber development GO:0048741 130 56 2,000 8,485E-04 0,01057554 ! regulation of protein catabolic process GO:0042176 126 56 2,000 8,485E-04 0,01052186 ! regulation of DNA replication GO:0006275 105 56 2,000 8,485E-04 0,01046872 ! positive regulation of caspase activity GO:0043280 108 57 2,000 8,935E-04 0,01096853 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 8,935E-04 0,01091369 ! nucleotide-excision repair GO:0006289 91 57 2,000 8,935E-04 0,01085939 ! positive regulation of cell migration GO:0030335 137 58 2,000 9,4E-04 0,01136783 ! aging GO:0007568 112 58 2,000 9,4E-04 0,01131183 ! regulation of S phase GO:0033261 26 14 1,000 9,526E-04 0,01140827 ! regulation of cellular pH GO:0030641 27 14 1,000 9,526E-04 0,01135262 ! regulation of RNA stability GO:0043487 33 14 1,000 9,526E-04 0,01129751 ! regulation of axon extension GO:0030516 43 14 1,000 9,526E-04 0,01124293 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 9,526E-04 0,01118888 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,097E-03 0,01282084 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,097E-03 0,01275979 ! regulation of mRNA processing GO:0050684 26 15 1,000 1,097E-03 0,01269932 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 1,097E-03 0,01263942 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,097E-03 0,01258008 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,097E-03 0,01252129 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 1,097E-03 0,01246305 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 1,251E-03 0,01414706 ! intermediate filament-based process GO:0045103 36 16 1,000 1,251E-03 0,01408187 ! axon cargo transport GO:0008088 46 16 1,000 1,251E-03 0,01401727 ! neuron recognition GO:0008038 40 16 1,000 1,251E-03 0,01395327 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,251E-03 0,01388985 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,251E-03 0,013827 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 1,251E-03 0,01376804 ! positive regulation of cell motion GO:0051272 157 65 2,000 1,309E-03 0,01433524 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 1,368E-03 0,01491517 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 1,415E-03 0,01535892 ! signal complex assembly GO:0007172 47 17 1,000 1,415E-03 0,01529096 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 1,415E-03 0,0152236 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 1,415E-03 0,01515683 ! NAD metabolic process GO:0019674 33 17 1,000 1,415E-03 0,01509064 ! cellular amino acid derivative catabolic process GO:0042219 30 17 1,000 1,415E-03 0,01502503 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 1,415E-03 0,01495999 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 1,415E-03 0,01489551 ! negative regulation of cell growth GO:0030308 142 67 2,000 1,428E-03 0,0149754 ! detection of external stimulus GO:0009581 102 68 2,000 1,491E-03 0,01556243 ! positive regulation of T cell activation GO:0050870 124 68 2,000 1,491E-03 0,01549621 ! negative regulation of cell size GO:0045792 144 69 2,000 1,555E-03 0,01609349 ! lung development GO:0030324 165 69 2,000 1,555E-03 0,01602558 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 1,555E-03 0,01595825 ! cellular amino acid catabolic process GO:0009063 120 69 2,000 1,555E-03 0,01589148 ! limbic system development GO:0021761 40 18 1,000 1,588E-03 0,01616405 ! patterning of blood vessels GO:0001569 43 18 1,000 1,588E-03 0,01609698 ! glycine metabolic process GO:0006544 30 18 1,000 1,588E-03 0,01603046 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 1,588E-03 0,01596449 ! nerve development GO:0021675 34 18 1,000 1,588E-03 0,01589907 ! respiratory tube development GO:0030323 171 72 2,000 1,757E-03 0,01752039 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,771E-03 0,01758721 ! pigmentation during development GO:0048066 42 19 1,000 1,771E-03 0,01751601 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 1,771E-03 0,01744538 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 1,901E-03 0,01864822 ! respiratory system development GO:0060541 175 74 2,000 1,901E-03 0,01857363 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 1,964E-03 0,01911094 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,964E-03 0,0190351 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,964E-03 0,01895986 ! forelimb morphogenesis GO:0035136 35 20 1,000 1,964E-03 0,01888522 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,964E-03 0,01881116 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,964E-03 0,01873768 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,964E-03 0,01866477 ! aromatic compound catabolic process GO:0019439 31 20 1,000 1,964E-03 0,01859242 ! regulation of transcription factor activity GO:0051090 137 75 2,000 1,975E-03 0,01863075 GO:0090046|regulation of transcription regulator activity, ! lymphocyte differentiation GO:0030098 193 76 2,000 2,051E-03 0,01927579 ! amine catabolic process GO:0009310 136 77 2,000 2,13E-03 0,01993282 ! regulation of catabolic process GO:0009894 173 77 2,000 2,13E-03 0,01985674 ! lipid phosphorylation GO:0046834 43 21 1,000 2,166E-03 0,02011556 ! plasma membrane fusion GO:0045026 33 21 1,000 2,166E-03 0,02003936 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 2,166E-03 0,01996374 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 2,166E-03 0,01988869 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 2,166E-03 0,0198142 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 2,209E-03 0,02014062 ! protein oligomerization GO:0051259 149 79 2,000 2,291E-03 0,02080817 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 2,377E-03 0,02150718 ! microtubule-based transport GO:0010970 59 22 1,000 2,377E-03 0,02142782 ! hindlimb morphogenesis GO:0035137 47 22 1,000 2,377E-03 0,02134904 ! cellular response to starvation GO:0009267 37 22 1,000 2,377E-03 0,02127083 ! positive regulation of locomotion GO:0040017 44 22 1,000 2,377E-03 0,0211932 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 1,000 2,377E-03 0,02111614 ! response to cytokine stimulus GO:0034097 69 22 1,000 2,377E-03 0,02103963 ! protein stabilization GO:0050821 41 22 1,000 2,377E-03 0,02096367 ! muscle cell differentiation GO:0042692 178 81 2,000 2,46E-03 0,02162031 ! response to hypoxia GO:0001666 178 81 2,000 2,46E-03 0,02154281 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 2,46E-03 0,02146587 ! protein import into nucleus GO:0006606 174 82 2,000 2,548E-03 0,02214892 ! viral genome replication GO:0019079 44 23 1,000 2,598E-03 0,02250471 ! regulation of chemotaxis GO:0050920 45 23 1,000 2,598E-03 0,02242519 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 2,598E-03 0,02234623 ! response to oxygen levels GO:0070482 183 83 2,000 2,637E-03 0,0226031 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 2,637E-03 0,02252407 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 2,000 2,637E-03 0,02244558 ! negative regulation of transport GO:0051051 164 85 2,000 2,821E-03 0,02393049 ! negative regulation of growth GO:0045926 168 85 2,000 2,821E-03 0,02384769 ! regulation of neuron differentiation GO:0045664 187 85 2,000 2,821E-03 0,02376545 ! barbed-end actin filament capping GO:0051016 58 24 1,000 2,828E-03 0,02374025 GO:0051693|actin filament capping, ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,828E-03 0,02365895 ! pallium development GO:0021543 56 24 1,000 2,828E-03 0,0235782 ! oogenesis GO:0048477 44 24 1,000 2,828E-03 0,023498 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 2,828E-03 0,02341835 ! negative regulation of catabolic process GO:0009895 52 24 1,000 2,828E-03 0,02333923 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 2,828E-03 0,02326065 ! positive regulation of cell activation GO:0050867 161 86 2,000 2,916E-03 0,02390641 GO:0002696|positive regulation of leukocyte activation, ! receptor metabolic process GO:0043112 53 25 1,000 3,067E-03 0,02506032 ! protein tetramerization GO:0051262 57 25 1,000 3,067E-03 0,02497679 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 3,067E-03 0,02489381 ! regulation of behavior GO:0050795 48 25 1,000 3,067E-03 0,02481138 ! regulation of DNA binding GO:0051101 167 89 2,000 3,213E-03 0,02590496 ! tube morphogenesis GO:0035239 194 89 2,000 3,213E-03 0,02581974 ! protein localization in nucleus GO:0034504 192 89 2,000 3,213E-03 0,02573509 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 3,316E-03 0,02647074 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 3,316E-03 0,02638452 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 50 26 1,000 3,316E-03 0,02629885 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 1,000 3,316E-03 0,02621374 ! neural tube closure GO:0001843 58 26 1,000 3,316E-03 0,02612918 GO:0060606|tube closure, ! positive regulation of protein modification process GO:0031401 156 90 2,000 3,316E-03 0,02604685 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 3,573E-03 0,02797851 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 3,573E-03 0,02788912 ! tube lumen formation GO:0035148 59 27 1,000 3,573E-03 0,0278003 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 3,573E-03 0,02771204 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 3,573E-03 0,02762435 ! mitochondrial membrane organization GO:0007006 60 27 1,000 3,573E-03 0,0275372 ! response to starvation GO:0042594 47 27 1,000 3,573E-03 0,02745061 ! cellular response to nutrient levels GO:0031669 45 27 1,000 3,573E-03 0,02736456 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 3,637E-03 0,02776284 ! nitrogen compound catabolic process GO:0044270 167 94 2,000 3,748E-03 0,02852087 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 3,84E-03 0,02913238 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 3,84E-03 0,02904219 ! protein amino acid acylation GO:0043543 59 28 1,000 3,84E-03 0,02895255 ! dendrite development GO:0016358 67 28 1,000 3,84E-03 0,02886347 ! vitamin biosynthetic process GO:0009110 48 28 1,000 3,84E-03 0,02877493 ! base-excision repair GO:0006284 41 28 1,000 3,84E-03 0,02868693 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 3,84E-03 0,02859947 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 3,84E-03 0,02851254 ! regulation of T cell activation GO:0050863 175 96 2,000 3,976E-03 0,02943156 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 4,093E-03 0,03020724 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 4,115E-03 0,03028282 ! primary neural tube formation GO:0014020 61 29 1,000 4,115E-03 0,03019188 ! response to organic cyclic substance GO:0014070 58 29 1,000 4,115E-03 0,03010149 ! somitogenesis GO:0001756 52 29 1,000 4,115E-03 0,03001163 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 4,115E-03 0,02992231 ! leukocyte differentiation GO:0002521 232 98 2,000 4,212E-03 0,03053372 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 4,4E-03 0,03180164 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 4,4E-03 0,03170783 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 4,4E-03 0,03161457 ! nicotinamide metabolic process GO:0006769 56 30 1,000 4,4E-03 0,03152186 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 4,4E-03 0,03142969 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 4,4E-03 0,03133806 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 1,000 4,693E-03 0,03333038 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 4,693E-03 0,03323377 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 4,693E-03 0,03313772 ! hindbrain development GO:0030902 65 32 1,000 4,995E-03 0,03516956 ! positive regulation of catabolic process GO:0009896 72 32 1,000 4,995E-03 0,0350685 ! regulation of pH GO:0006885 56 33 1,000 5,306E-03 0,03714433 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 5,306E-03 0,0370382 ! regulation of axonogenesis GO:0050770 86 33 1,000 5,306E-03 0,03693268 ! pyridine nucleotide metabolic process GO:0019362 60 33 1,000 5,306E-03 0,03682776 ! glial cell differentiation GO:0010001 67 34 1,000 5,626E-03 0,03893513 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 5,626E-03 0,03882514 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 5,954E-03 0,04097433 ! telencephalon development GO:0021537 81 35 1,000 5,954E-03 0,04085923 ! regulation of muscle development GO:0048634 82 36 1,000 6,291E-03 0,04304924 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 6,291E-03 0,04292899 ! negative regulation of DNA binding GO:0043392 67 36 1,000 6,291E-03 0,04280941 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 6,291E-03 0,0426905 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 6,636E-03 0,04490869 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 6,636E-03 0,04478464 ! xenobiotic metabolic process GO:0006805 55 37 1,000 6,636E-03 0,04466126 ! tissue remodeling GO:0048771 78 37 1,000 6,636E-03 0,04453857 ! maintenance of protein location in cell GO:0032507 89 37 1,000 6,636E-03 0,04441654 ! female gonad development GO:0008585 71 37 1,000 6,636E-03 0,04429519 ! regulation of microtubule-based process GO:0032886 86 37 1,000 6,636E-03 0,04417449 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 6,99E-03 0,0464025 ! regulation of protein stability GO:0031647 77 38 1,000 6,99E-03 0,04627675 ! glycogen metabolic process GO:0005977 63 38 1,000 6,99E-03 0,04615167 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 6,99E-03 0,04602728 ! neural tube formation GO:0001841 79 38 1,000 6,99E-03 0,04590355 ! regulation of neuron projection development GO:0010975 102 39 1,000 7,352E-03 0,04815195 ! negative regulation of binding GO:0051100 71 39 1,000 7,352E-03 0,04802321 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 7,352E-03 0,04789514 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 7,352E-03 0,04776776 ! glucan metabolic process GO:0044042 64 39 1,000 7,352E-03 0,04764106 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 7,722E-03 0,04990893 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 7,722E-03 0,04977725 GO:0046660|female sex differentiation, ! cellular amide metabolic process GO:0043603 73 41 1,000 8,101E-03 0,05208071 ! gliogenesis GO:0042063 91 41 1,000 8,101E-03 0,05194401 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 8,101E-03 0,05180804 ! maintenance of protein location GO:0045185 95 41 1,000 8,101E-03 0,05167277 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 8,101E-03 0,0515382 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 8,488E-03 0,05385927 ! cytokinesis GO:0000910 84 42 1,000 8,488E-03 0,05371974 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 8,488E-03 0,05358093 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 8,883E-03 0,05593011 GO:0090047|positive regulation of transcription regulator activity, ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 8,883E-03 0,05578633 ! segmentation GO:0035282 78 43 1,000 8,883E-03 0,05564329 ! neuron migration GO:0001764 85 43 1,000 8,883E-03 0,05550098 ! energy reserve metabolic process GO:0006112 76 44 1,000 9,286E-03 0,05787175 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 9,286E-03 0,0577245 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 9,286E-03 0,05757799 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 9,697E-03 0,05997521 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 9,697E-03 0,05982376 ! keratinocyte differentiation GO:0030216 81 45 1,000 9,697E-03 0,05967307 ! B cell differentiation GO:0030183 124 45 1,000 9,697E-03 0,05952314 ! female gamete generation GO:0007292 71 45 1,000 9,697E-03 0,05937396 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 1,000 9,697E-03 0,05922552 ! developmental growth GO:0048589 88 45 1,000 9,697E-03 0,05907783 ! maintenance of location in cell GO:0051651 101 45 1,000 9,697E-03 0,05893087 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,01011633 0,06132554 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01011633 0,06117374 ! pigmentation GO:0043473 103 46 1,000 0,01011633 0,06102269 ! neural tube development GO:0021915 91 47 1,000 0,0105434 0,06344221 ! response to insulin stimulus GO:0032868 98 47 1,000 0,0105434 0,06328633 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01097835 0,06573557 ! mitochondrial transport GO:0006839 94 48 1,000 0,01097835 0,06557485 ! endosome transport GO:0016197 127 48 1,000 0,01097835 0,06541491 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01097835 0,06525575 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,01097835 0,06509736 ! protein homooligomerization GO:0051260 84 49 1,000 0,01142111 0,06755879 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01187163 0,07005411 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,01232986 0,07258277 ! viral infectious cycle GO:0019058 104 51 1,000 0,01232986 0,07240829 ! positive regulation of binding GO:0051099 88 52 1,000 0,01279574 0,07496399 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,01279574 0,07478465 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,01279574 0,07460617 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,01279574 0,07442854 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,01279574 0,07425175 ! histone modification GO:0016570 104 52 1,000 0,01279574 0,07407579 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,01279574 0,07390067 ! amino acid activation GO:0043038 98 52 1,000 0,01279574 0,07372638 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! chromatin remodeling GO:0006338 122 53 1,000 0,01326921 0,07627454 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,01326921 0,07609549 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,01326921 0,07591728 ! regulation of translational initiation GO:0006446 87 54 1,000 0,01375022 0,0784855 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,01375022 0,07830255 ! membrane fusion GO:0006944 122 54 1,000 0,01375022 0,07812045 ! covalent chromatin modification GO:0016569 115 54 1,000 0,01375022 0,0779392 ! regulation of cell shape GO:0008360 142 54 1,000 0,01375022 0,07775878 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,01375022 0,0775792 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,01423872 0,08015024 ! cell recognition GO:0008037 98 55 1,000 0,01423872 0,07996598 ! cell maturation GO:0048469 107 55 1,000 0,01423872 0,07978258 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,01423872 0,07960001 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01473466 0,08218441 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01523798 0,08479812 ! regulation of actin filament length GO:0030832 118 58 1,000 0,01574862 0,08744063 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01574862 0,08724235 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01574862 0,08704497 ! maintenance of location GO:0051235 124 58 1,000 0,01574862 0,08684848 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01635139 0,08996948 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01635139 0,0897673 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01635139 0,08956603 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01635139 0,08936566 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01635139 0,08916618 ! neuron fate determination GO:0048664 7 5 0,000 0,01635139 0,08896759 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01635139 0,08876989 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01635139 0,08857306 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01635139 0,0883771 ! polyol transport GO:0015791 12 5 0,000 0,01635139 0,08818201 ! response to superoxide GO:0000303 10 5 0,000 0,01635139 0,08798777 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01635139 0,08779439 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,01635139 0,08760186 ! female meiosis GO:0007143 10 5 0,000 0,01635139 0,08741017 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01635139 0,08721932 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01635139 0,0870293 ! hypothalamus development GO:0021854 9 5 0,000 0,01635139 0,08684011 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01635139 0,08665173 ! cobalt ion transport GO:0006824 11 5 0,000 0,01635139 0,08646418 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01635139 0,08627743 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01635139 0,08609149 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01635139 0,08590634 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01635139 0,08572199 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01635139 0,08553844 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01635139 0,08535566 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01635139 0,08517367 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01635139 0,08499245 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01635139 0,08481199 ! transposition GO:0032196 9 5 0,000 0,01635139 0,08463231 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01635139 0,08445338 ! negative chemotaxis GO:0050919 16 5 0,000 0,01635139 0,08427521 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01635139 0,08409779 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01635139 0,08392111 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01635139 0,08374518 ! behavioral response to pain GO:0048266 10 5 0,000 0,01635139 0,08356998 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01635139 0,08339551 ! Notch receptor processing GO:0007220 11 5 0,000 0,01635139 0,08322177 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01635139 0,08304875 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01635139 0,08287645 ! micturition GO:0060073 9 5 0,000 0,01635139 0,08270486 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01635139 0,08253399 ! copulation GO:0007620 9 5 0,000 0,01635139 0,08236381 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01635139 0,08219434 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01635139 0,08202556 ! bioluminescence GO:0008218 9 5 0,000 0,01635139 0,08185748 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01635139 0,08169008 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01635139 0,08152337 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01635139 0,08135733 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01635139 0,08119197 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01635139 0,08102728 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01635139 0,08086326 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01635139 0,0806999 ! grooming behavior GO:0007625 6 5 0,000 0,01635139 0,0805372 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01635139 0,08037515 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01635139 0,08021375 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01635139 0,08005301 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01635139 0,0798929 ! response to protozoan GO:0001562 13 5 0,000 0,01635139 0,07973343 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01635139 0,0795746 ! lymph vessel development GO:0001945 10 5 0,000 0,01635139 0,0794164 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01635139 0,07925883 ! endochondral ossification GO:0001958 17 5 0,000 0,01635139 0,07910188 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01635139 0,07894555 ! single strand break repair GO:0000012 8 5 0,000 0,01635139 0,07878984 ! parathyroid gland development GO:0060017 14 5 0,000 0,01635139 0,07863474 ! anagen GO:0042640 7 5 0,000 0,01635139 0,07848025 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01635139 0,07832637 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01635139 0,07817309 ! cytokine secretion GO:0050663 15 5 0,000 0,01635139 0,07802041 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01635139 0,07786832 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01635139 0,07771683 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01635139 0,07756592 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01635139 0,0774156 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01635139 0,07726586 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01635139 0,0771167 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01635139 0,07696811 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01635139 0,0768201 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01635139 0,07667265 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01635139 0,07652577 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01635139 0,07637944 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01635139 0,07623368 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01635139 0,07608848 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01635139 0,07594382 ! microvillus organization GO:0032528 8 5 0,000 0,01635139 0,07579971 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01635139 0,07565615 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01635139 0,07551314 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01635139 0,07537066 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01635139 0,07522872 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01635139 0,07508731 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01635139 0,07494643 ! polyol catabolic process GO:0046174 9 5 0,000 0,01635139 0,07480609 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01635139 0,07466626 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01635139 0,07452696 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01635139 0,07438817 ! muscle cell migration GO:0014812 8 5 0,000 0,01635139 0,07424991 ! mitochondrial fission GO:0000266 8 5 0,000 0,01635139 0,07411215 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01635139 0,07397491 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01635139 0,07383817 ! mRNA transcription GO:0009299 10 5 0,000 0,01635139 0,07370194 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01635139 0,07356621 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01635139 0,07343097 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01635139 0,07329624 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01635139 0,073162 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01635139 0,07302824 ! monocyte activation GO:0042117 10 5 0,000 0,01635139 0,07289498 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01635139 0,0727622 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01635139 0,07262991 ! response to food GO:0032094 6 5 0,000 0,01635139 0,07249809 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01635139 0,07236676 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01635139 0,07223589 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01635139 0,0721055 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01635139 0,07197558 ! forebrain neuron development GO:0021884 13 5 0,000 0,01635139 0,07184613 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01635139 0,07171714 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01635139 0,07158862 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01635139 0,07146055 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01635139 0,07133295 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01635139 0,07120579 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01635139 0,07107909 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01635139 0,07095284 ! lipid glycosylation GO:0030259 7 5 0,000 0,01635139 0,07082704 ! nucleobase transport GO:0015851 6 5 0,000 0,01635139 0,07070168 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01635139 0,07057677 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01635139 0,07045229 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01635139 0,07032826 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01635139 0,07020466 ! basic amino acid transport GO:0015802 12 5 0,000 0,01635139 0,07008149 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01635139 0,06995876 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01635139 0,06983645 ! actin nucleation GO:0045010 11 5 0,000 0,01635139 0,06971457 ! depurination GO:0045007 5 5 0,000 0,01635139 0,06959312 ! depyrimidination GO:0045008 10 5 0,000 0,01635139 0,06947209 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01635139 0,06935148 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01635139 0,06923128 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01635139 0,0691115 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01635139 0,06899214 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01635139 0,06887319 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01635139 0,06875465 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01635139 0,06863651 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01635139 0,06851878 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01635139 0,06840145 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01635139 0,06828453 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01635139 0,068168 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01635139 0,06805187 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01635139 0,06793614 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01635139 0,0678208 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01635139 0,06770585 ! response to arsenic GO:0046685 11 5 0,000 0,01635139 0,06759129 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01635139 0,06747711 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01635139 0,06736332 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01635139 0,06724992 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01635139 0,06713689 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01635139 0,06702424 ! response to mercury ion GO:0046689 8 5 0,000 0,01635139 0,06691198 ! response to cadmium ion GO:0046686 7 5 0,000 0,01635139 0,06680008 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01635139 0,06668856 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01635139 0,06657742 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01635139 0,06646664 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01635139 0,06635623 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01635139 0,06624619 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01635139 0,06613651 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01635139 0,06602719 ! decidualization GO:0046697 11 5 0,000 0,01635139 0,06591823 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01635139 0,06580964 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01635139 0,0657014 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01635139 0,06559351 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01635139 0,06548598 ! embryonic cleavage GO:0040016 6 5 0,000 0,01635139 0,0653788 ! peroxisome fission GO:0016559 5 5 0,000 0,01635139 0,06527198 ! histone demethylation GO:0016577 13 5 0,000 0,01635139 0,0651655 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01635139 0,06505936 ! mitotic recombination GO:0006312 9 5 0,000 0,01635139 0,06495358 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01635139 0,06484813 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01635139 0,06474303 ! metaphase plate congression GO:0051310 7 5 0,000 0,01635139 0,06463827 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01635139 0,06453384 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01635139 0,06442976 ! enteric nervous system development GO:0048484 8 5 0,000 0,01635139 0,06432601 ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01635139 0,06422259 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01635139 0,0641195 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01635139 0,06401675 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01635139 0,06391432 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01635139 0,06381222 ! B cell homeostasis GO:0001782 13 5 0,000 0,01635139 0,06371045 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01635139 0,063609 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01635139 0,06350787 ! metaphase GO:0051323 11 5 0,000 0,01635139 0,06340706 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01635139 0,06330658 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01635139 0,06320641 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01635139 0,06310656 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01635139 0,06300702 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01635139 0,06290779 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01635139 0,06280888 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01635139 0,06271028 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01635139 0,06261199 ! response to redox state GO:0051775 6 5 0,000 0,01635139 0,06251401 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01635139 0,06241633 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01635139 0,06231895 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01635139 0,06222188 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01635139 0,06212512 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01635139 0,06202865 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01635139 0,06193248 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01635139 0,06183661 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01635139 0,06174103 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01635139 0,06164576 ! striatum development GO:0021756 14 5 0,000 0,01635139 0,06155077 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01635139 0,06145608 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01635139 0,06136167 ! glial cell migration GO:0008347 10 5 0,000 0,01635139 0,06126756 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01635139 0,06117374 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01635139 0,0610802 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01635139 0,06098695 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01635139 0,06089398 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01635139 0,06080129 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01635139 0,06070889 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01635139 0,06061677 ! neuroprotection GO:0043526 8 5 0,000 0,01635139 0,06052492 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01635139 0,06043336 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01635139 0,06034207 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01635139 0,06025106 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01635139 0,06016032 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01635139 0,06006985 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01635139 0,05997965 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01635139 0,05988973 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01635139 0,05980007 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01635139 0,05971069 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01635139 0,05962157 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01635139 0,05953271 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01635139 0,05944412 ! spindle assembly GO:0051225 6 5 0,000 0,01635139 0,05935579 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01635139 0,05926773 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01635139 0,05917993 ! protein palmitoylation GO:0018345 12 5 0,000 0,01635139 0,05909238 ! drug metabolic process GO:0017144 7 5 0,000 0,01635139 0,0590051 ! stem cell division GO:0017145 11 5 0,000 0,01635139 0,05891807 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01635139 0,0588313 ! organ regeneration GO:0031100 7 5 0,000 0,01635139 0,05874478 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01635139 0,05865852 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01635139 0,05857251 ! lipid modification GO:0030258 112 60 1,000 0,01679168 0,0600616 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,01679168 0,05997379 ! regulation of cellular component size GO:0032535 125 61 1,000 0,01732399 0,06178468 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,01732399 0,06169462 ! viral reproductive process GO:0022415 132 62 1,000 0,01786342 0,06352304 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01786342 0,06343071 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,01840991 0,06527637 ! mesoderm development GO:0007498 128 63 1,000 0,01840991 0,06518176 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,01840991 0,06508743 ! water-soluble vitamin metabolic process GO:0006767 107 63 1,000 0,01840991 0,06499338 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,01896342 0,06685085 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,01896342 0,06675452 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01958972 0,06885997 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01958972 0,06876104 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01958972 0,06866238 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01958972 0,06856401 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01958972 0,06846592 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01958972 0,06836812 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01958972 0,06827059 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01958972 0,06817334 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01958972 0,06807636 ! response to oxygen radical GO:0000305 11 6 0,000 0,01958972 0,06797966 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01958972 0,06788324 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01958972 0,06778708 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01958972 0,0676912 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01958972 0,0675956 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01958972 0,06750026 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01958972 0,06740519 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01958972 0,06731038 ! forebrain regionalization GO:0021871 9 6 0,000 0,01958972 0,06721584 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01958972 0,06712157 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01958972 0,06702756 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01958972 0,06693382 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01958972 0,06684034 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01958972 0,06674711 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01958972 0,06665415 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01958972 0,06656145 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01958972 0,066469 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01958972 0,06637681 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01958972 0,06628488 ! malate metabolic process GO:0006108 13 6 0,000 0,01958972 0,0661932 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01958972 0,06610177 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01958972 0,06601059 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01958972 0,06591967 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01958972 0,065829 ! protein refolding GO:0042026 15 6 0,000 0,01958972 0,06573857 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01958972 0,0656484 ! opsonization GO:0008228 8 6 0,000 0,01958972 0,06555847 ! mating behavior GO:0007617 7 6 0,000 0,01958972 0,06546878 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01958972 0,06537935 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01958972 0,06529015 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01958972 0,0652012 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01958972 0,06511249 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01958972 0,06502402 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01958972 0,0649358 ! toxin metabolic process GO:0009404 11 6 0,000 0,01958972 0,06484781 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01958972 0,06476006 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01958972 0,06467254 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01958972 0,06458526 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01958972 0,06449822 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01958972 0,06441142 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01958972 0,06432484 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01958972 0,0642385 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01958972 0,06415239 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01958972 0,06406651 ! thymic T cell selection GO:0045061 16 6 0,000 0,01958972 0,06398086 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01958972 0,06389544 ! protein lipoylation GO:0009249 10 6 0,000 0,01958972 0,06381024 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01958972 0,06372527 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01958972 0,06364053 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01958972 0,06355602 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01958972 0,06347173 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01958972 0,06338766 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01958972 0,06330381 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01958972 0,06322019 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01958972 0,06313678 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01958972 0,0630536 ! hyperosmotic response GO:0006972 10 6 0,000 0,01958972 0,06297063 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01958972 0,06288789 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01958972 0,06280536 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01958972 0,06272304 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01958972 0,06264094 ! urea metabolic process GO:0019627 7 6 0,000 0,01958972 0,06255906 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01958972 0,06247739 ! neutrophil activation GO:0042119 7 6 0,000 0,01958972 0,06239593 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01958972 0,06231469 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01958972 0,06223366 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01958972 0,06215283 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01958972 0,06207222 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01958972 0,06199182 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01958972 0,06191162 ! neuron apoptosis GO:0051402 15 6 0,000 0,01958972 0,06183163 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01958972 0,06175185 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01958972 0,06167227 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01958972 0,0615929 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01958972 0,06151373 ! carnitine transport GO:0015879 10 6 0,000 0,01958972 0,06143476 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01958972 0,061356 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01958972 0,06127744 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01958972 0,06119908 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01958972 0,06112092 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01958972 0,06104296 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01958972 0,0609652 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01958972 0,06088764 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01958972 0,06081027 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01958972 0,0607331 ! astrocyte development GO:0014002 16 6 0,000 0,01958972 0,06065612 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01958972 0,06057934 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01958972 0,06050276 ! interaction with symbiont GO:0051702 14 6 0,000 0,01958972 0,06042637 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01958972 0,06035017 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01958972 0,06027416 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01958972 0,06019834 ! response to copper ion GO:0046688 10 6 0,000 0,01958972 0,06012272 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01958972 0,06004728 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01958972 0,05997203 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01958972 0,05989697 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01958972 0,0598221 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01958972 0,05974742 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01958972 0,05967292 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01958972 0,05959861 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01958972 0,05952448 ! hair follicle maturation GO:0048820 8 6 0,000 0,01958972 0,05945054 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01958972 0,05937678 ! Schwann cell development GO:0014044 15 6 0,000 0,01958972 0,0593032 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01958972 0,0592298 ! response to pheromone GO:0019236 6 6 0,000 0,01958972 0,05915659 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01958972 0,05908356 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01958972 0,0590107 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01958972 0,05893803 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01958972 0,05886554 ! subpallium development GO:0021544 15 6 0,000 0,01958972 0,05879322 ! neural tube patterning GO:0021532 8 6 0,000 0,01958972 0,05872108 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01958972 0,05864912 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01958972 0,05857733 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01958972 0,05850572 ! G2 phase GO:0051319 16 6 0,000 0,01958972 0,05843429 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01958972 0,05836303 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01958972 0,05829194 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01958972 0,05822102 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01958972 0,05815028 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01958972 0,05807971 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01958972 0,05800931 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01958972 0,05793908 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01958972 0,05786902 ! receptor internalization GO:0031623 11 6 0,000 0,01958972 0,05779913 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01958972 0,05772941 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01958972 0,05765986 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01958972 0,05759047 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01958972 0,05752125 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01958972 0,0574522 ! protein deubiquitination GO:0016579 16 6 0,000 0,01958972 0,05738331 ! protein destabilization GO:0031648 9 6 0,000 0,01958972 0,05731459 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01958972 0,05724603 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01958972 0,05717764 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01958972 0,0571094 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01958972 0,05704134 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01958972 0,05697343 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01958972 0,05690569 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01958972 0,0568381 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01958972 0,05677068 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01958972 0,05670341 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01958972 0,05663631 ! neural plate development GO:0001840 9 6 0,000 0,01958972 0,05656936 ! catecholamine transport GO:0051937 9 6 0,000 0,01958972 0,05650258 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01958972 0,05643594 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01958972 0,05636947 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01958972 0,05630315 ! maternal placenta development GO:0001893 12 6 0,000 0,01958972 0,05623699 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01958972 0,05617099 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01958972 0,05610514 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01958972 0,05603944 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01958972 0,0559739 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01958972 0,05590851 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01958972 0,05584327 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01958972 0,05577818 GO:0055081|anion homeostasis, ! gonad development GO:0008406 115 66 1,000 0,02009128 0,05713969 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,02066553 0,05870451 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 125 67 1,000 0,02066553 0,05863633 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,02124658 0,06021508 ! viral reproduction GO:0016032 142 68 1,000 0,02124658 0,06014531 ! adaptive immune response GO:0002250 126 68 1,000 0,02124658 0,0600757 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,0218344 0,06166641 ! developmental maturation GO:0021700 128 69 1,000 0,0218344 0,0615952 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,02242893 0,0631994 ! germ cell development GO:0007281 133 70 1,000 0,02242893 0,06312659 ! tRNA transcription GO:0009304 17 7 0,000 0,02281747 0,06414625 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02281747 0,06407252 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02281747 0,06399896 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02281747 0,06392556 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02281747 0,06385234 ! sleep GO:0030431 16 7 0,000 0,02281747 0,06377928 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02281747 0,06370639 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02281747 0,06363366 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02281747 0,06356111 ! prostate gland development GO:0030850 14 7 0,000 0,02281747 0,06348871 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02281747 0,06341648 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02281747 0,06334442 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02281747 0,06327252 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02281747 0,06320078 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02281747 0,06312921 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02281747 0,06305779 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02281747 0,06298654 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02281747 0,06291545 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02281747 0,06284452 ! glycolipid transport GO:0046836 11 7 0,000 0,02281747 0,06277375 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02281747 0,06270314 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02281747 0,06263269 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02281747 0,06256239 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02281747 0,06249225 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02281747 0,06242227 ! pericardium development GO:0060039 16 7 0,000 0,02281747 0,06235245 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02281747 0,06228278 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02281747 0,06221327 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02281747 0,06214391 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02281747 0,06207471 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02281747 0,06200566 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02281747 0,06193677 ! lipoprotein transport GO:0042953 14 7 0,000 0,02281747 0,06186802 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02281747 0,06179943 ! rhythmic behavior GO:0007622 17 7 0,000 0,02281747 0,061731 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02281747 0,06166271 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02281747 0,06159457 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02281747 0,06152659 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02281747 0,06145875 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02281747 0,06139107 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02281747 0,06132353 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02281747 0,06125614 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02281747 0,0611889 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02281747 0,06112181 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02281747 0,06105486 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02281747 0,06098806 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02281747 0,06092141 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02281747 0,0608549 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02281747 0,06078854 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02281747 0,06072232 ! spinal cord patterning GO:0021511 14 7 0,000 0,02281747 0,06065625 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02281747 0,06059032 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02281747 0,06052453 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02281747 0,06045888 ! adrenal gland development GO:0030325 17 7 0,000 0,02281747 0,06039338 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02281747 0,06032802 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02281747 0,0602628 ! ovulation GO:0030728 10 7 0,000 0,02281747 0,06019772 ! adenohypophysis development GO:0021984 11 7 0,000 0,02281747 0,06013278 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02281747 0,06006798 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02281747 0,06000333 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02281747 0,05993881 ! microtubule nucleation GO:0007020 21 7 0,000 0,02281747 0,05987443 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02281747 0,05981018 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02281747 0,05974608 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02281747 0,05968211 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02281747 0,05961828 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02281747 0,05955458 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02281747 0,05949102 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02281747 0,0594276 ! galactose metabolic process GO:0006012 13 7 0,000 0,02281747 0,05936431 ! vesicle fusion GO:0006906 20 7 0,000 0,02281747 0,05930116 ! response to dietary excess GO:0002021 8 7 0,000 0,02281747 0,05923814 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02281747 0,05917525 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02281747 0,0591125 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02281747 0,05904988 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02281747 0,0589874 ! organ growth GO:0035265 15 7 0,000 0,02281747 0,05892504 ! nucleoside transport GO:0015858 11 7 0,000 0,02281747 0,05886282 ! nucleoside salvage GO:0043174 11 7 0,000 0,02281747 0,05880073 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02281747 0,05873877 ! male sex determination GO:0030238 15 7 0,000 0,02281747 0,05867694 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02281747 0,05861524 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02281747 0,05855367 ! parturition GO:0007567 16 7 0,000 0,02281747 0,05849222 ! rRNA modification GO:0000154 14 7 0,000 0,02281747 0,05843091 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02281747 0,05836973 ! spindle checkpoint GO:0031577 16 7 0,000 0,02281747 0,05830867 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02281747 0,05824774 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02281747 0,05818694 ! monocyte differentiation GO:0030224 16 7 0,000 0,02281747 0,05812627 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02281747 0,05806572 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02281747 0,0580053 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02281747 0,057945 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02281747 0,05788483 ! fibrinolysis GO:0042730 11 7 0,000 0,02281747 0,05782478 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02281747 0,05776486 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02281747 0,05770506 ! eating behavior GO:0042755 8 7 0,000 0,02281747 0,05764539 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02281747 0,05758584 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02281747 0,05752641 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02281747 0,0574671 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02281747 0,05740792 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02281747 0,05734886 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02281747 0,05728992 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02281747 0,0572311 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02281747 0,0571724 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02281747 0,05711382 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02281747 0,05705536 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02281747 0,05699702 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02281747 0,0569388 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02281747 0,0568807 ! histone ubiquitination GO:0016574 9 7 0,000 0,02281747 0,05682272 ! regulation of meiosis GO:0040020 12 7 0,000 0,02281747 0,05676486 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02281747 0,05670711 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02281747 0,05664948 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02281747 0,05659197 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02281747 0,05653457 ! transcription termination GO:0006353 14 7 0,000 0,02281747 0,05647729 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02281747 0,05642013 ! anaphase GO:0051322 18 7 0,000 0,02281747 0,05636308 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02281747 0,05630615 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02281747 0,05624933 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02281747 0,05619263 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02281747 0,05613604 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02281747 0,05607957 ! diuresis GO:0030146 12 7 0,000 0,02281747 0,05602321 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02281747 0,05596696 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02281747 0,05591082 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02281747 0,0558548 ! antibiotic transport GO:0042891 9 7 0,000 0,02281747 0,05579889 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02281747 0,05574309 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02281747 0,0556874 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02281747 0,05563183 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02281747 0,05557636 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02281747 0,05552101 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02281747 0,05546576 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02281747 0,05541063 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02281747 0,0553556 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02281747 0,05530068 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02281747 0,05524588 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02281747 0,05519118 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02281747 0,05513659 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02281747 0,0550821 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02281747 0,05502773 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02281747 0,05497346 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02281747 0,0549193 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02281747 0,05486525 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02281747 0,0548113 ! muscle adaptation GO:0043500 13 7 0,000 0,02281747 0,05475746 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02281747 0,05470372 ! retina homeostasis GO:0001895 12 7 0,000 0,02281747 0,05465009 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02281747 0,05459656 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02281747 0,05454314 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02281747 0,05448982 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02281747 0,05443661 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,02303012 0,05489033 ! appendage morphogenesis GO:0035107 150 72 1,000 0,02363792 0,05628406 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 1,000 0,02363792 0,05622925 ! B cell activation GO:0042113 179 72 1,000 0,02363792 0,05617456 ! coenzyme biosynthetic process GO:0009108 119 72 1,000 0,02363792 0,05611996 ! appendage development GO:0048736 151 73 1,000 0,02425229 0,05752266 GO:0060173|limb development, ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,02487316 0,05893806 ! reproductive structure development GO:0048608 131 75 1,000 0,02550051 0,06036602 ! axon guidance GO:0007411 162 75 1,000 0,02550051 0,06030759 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02603469 0,06151137 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02603469 0,06145194 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,02603469 0,06139262 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02603469 0,06133342 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02603469 0,06127433 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02603469 0,06121536 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02603469 0,0611565 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02603469 0,06109775 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02603469 0,06103912 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02603469 0,06098059 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02603469 0,06092218 ! meiotic prophase I GO:0007128 14 8 0,000 0,02603469 0,06086388 ! response to zinc ion GO:0010043 12 8 0,000 0,02603469 0,0608057 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02603469 0,06074762 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02603469 0,06068966 ! oligopeptide transport GO:0006857 16 8 0,000 0,02603469 0,0606318 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02603469 0,06057406 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02603469 0,06051642 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02603469 0,0604589 ! signal peptide processing GO:0006465 12 8 0,000 0,02603469 0,06040148 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02603469 0,06034417 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02603469 0,06028698 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02603469 0,06022989 ! succinate metabolic process GO:0006105 17 8 0,000 0,02603469 0,0601729 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02603469 0,06011603 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02603469 0,06005926 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02603469 0,0600026 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02603469 0,05994605 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02603469 0,0598896 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02603469 0,05983326 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02603469 0,05977703 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02603469 0,0597209 ! reflex GO:0060004 17 8 0,000 0,02603469 0,05966488 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02603469 0,05960896 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02603469 0,05955315 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02603469 0,05949744 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02603469 0,05944183 ! pigment granule organization GO:0048753 17 8 0,000 0,02603469 0,05938633 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02603469 0,05933093 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02603469 0,05927564 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02603469 0,05922045 ! histidine catabolic process GO:0006548 10 8 0,000 0,02603469 0,05916536 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02603469 0,05911037 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02603469 0,05905549 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02603469 0,0590007 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02603469 0,05894602 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02603469 0,05889144 ! melanin metabolic process GO:0006582 17 8 0,000 0,02603469 0,05883696 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02603469 0,05878259 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02603469 0,05872831 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02603469 0,05867413 ! macrophage activation GO:0042116 13 8 0,000 0,02603469 0,05862005 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02603469 0,05856608 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02603469 0,0585122 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02603469 0,05845842 ! purine salvage GO:0043101 12 8 0,000 0,02603469 0,05840474 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02603469 0,05835116 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02603469 0,05829767 ! osteoblast development GO:0002076 17 8 0,000 0,02603469 0,05824428 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02603469 0,058191 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02603469 0,05813781 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02603469 0,05808471 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02603469 0,05803171 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02603469 0,05797881 ! response to UV-B GO:0010224 17 8 0,000 0,02603469 0,05792601 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02603469 0,0578733 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02603469 0,05782069 ! intermediate filament organization GO:0045109 12 8 0,000 0,02603469 0,05776817 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02603469 0,05771575 ! cellular extravasation GO:0045123 13 8 0,000 0,02603469 0,05766343 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02603469 0,05761119 ! response to antibiotic GO:0046677 11 8 0,000 0,02603469 0,05755906 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02603469 0,05750702 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02603469 0,05745507 ! DNA topological change GO:0006265 12 8 0,000 0,02603469 0,05740321 ! response to tropane GO:0014073 15 8 0,000 0,02603469 0,05735145 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02603469 0,05729978 ! melanosome transport GO:0032402 13 8 0,000 0,02603469 0,05724821 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02603469 0,05719673 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02603469 0,05714534 ! mast cell activation GO:0045576 14 8 0,000 0,02603469 0,05709404 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02603469 0,05704283 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02603469 0,05699172 ! gas homeostasis GO:0033483 14 8 0,000 0,02603469 0,0569407 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02603469 0,05688977 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02603469 0,05683893 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02603469 0,05678818 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02603469 0,05673752 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02603469 0,05668695 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02603469 0,05663647 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02603469 0,05658608 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02603469 0,05653579 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02603469 0,05648558 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02603469 0,05643546 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02603469 0,05638542 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02603469 0,05633548 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02603469 0,05628563 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02603469 0,05623586 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02603469 0,05618618 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02603469 0,05613659 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02603469 0,05608709 ! hormone catabolic process GO:0042447 17 8 0,000 0,02603469 0,05603767 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02603469 0,05598834 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02603469 0,0559391 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02603469 0,05588995 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02603469 0,05584088 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02603469 0,05579189 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02603469 0,055743 ! adult feeding behavior GO:0008343 10 8 0,000 0,02603469 0,05569418 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02603469 0,05564546 ! ATP catabolic process GO:0006200 11 8 0,000 0,02603469 0,05559682 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02603469 0,05554826 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02603469 0,05549979 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02603469 0,0554514 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02603469 0,0554031 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02603469 0,05535488 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02603469 0,05530675 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02603469 0,0552587 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02603469 0,05521073 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02603469 0,05516284 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02603469 0,05511504 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02603469 0,05506732 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02603469 0,05501969 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02603469 0,05497213 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02603469 0,05492466 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02603469 0,05487727 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02603469 0,05482996 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02603469 0,05478274 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02603469 0,05473559 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,02613426 0,05489768 ! learning or memory GO:0007611 161 76 1,000 0,02613426 0,05485052 ! antigen processing and presentation GO:0019882 117 78 1,000 0,02742084 0,05750137 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,02807355 0,05881963 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,02807355 0,05876923 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,0287325 0,06009716 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,0287325 0,06004575 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0287325 0,05999443 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,0287325 0,0599432 ! axon extension GO:0048675 16 9 0,000 0,02924141 0,06095288 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02924141 0,06090091 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02924141 0,06084904 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02924141 0,06079725 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02924141 0,06074555 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02924141 0,06069394 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02924141 0,06064242 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02924141 0,06059099 ! reproductive behavior GO:0019098 22 9 0,000 0,02924141 0,06053964 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02924141 0,06048838 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02924141 0,0604372 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02924141 0,06038611 ! UTP metabolic process GO:0046051 10 9 0,000 0,02924141 0,06033511 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02924141 0,0602842 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02924141 0,06023337 ! artery development GO:0060840 25 9 0,000 0,02924141 0,06018262 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02924141 0,06013196 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02924141 0,06008139 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02924141 0,0600309 ! equilibrioception GO:0050957 20 9 0,000 0,02924141 0,0599805 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02924141 0,05993018 ! chemosensory behavior GO:0007635 21 9 0,000 0,02924141 0,05987994 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02924141 0,05982979 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02924141 0,05977973 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02924141 0,05972974 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02924141 0,05967984 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02924141 0,05963003 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02924141 0,05958029 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02924141 0,05953064 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02924141 0,05948108 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02924141 0,05943159 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02924141 0,05938219 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02924141 0,05933287 ! protein targeting to ER GO:0045047 25 9 0,000 0,02924141 0,05928363 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02924141 0,05923447 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02924141 0,05918539 ! T cell selection GO:0045058 27 9 0,000 0,02924141 0,0591364 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02924141 0,05908749 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02924141 0,05903865 ! endosome organization GO:0007032 20 9 0,000 0,02924141 0,0589899 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02924141 0,05894123 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02924141 0,05889264 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02924141 0,05884413 ! mannose metabolic process GO:0006013 13 9 0,000 0,02924141 0,0587957 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02924141 0,05874735 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02924141 0,05869907 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02924141 0,05865088 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02924141 0,05860277 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02924141 0,05855473 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02924141 0,05850677 ! retinol metabolic process GO:0042572 20 9 0,000 0,02924141 0,0584589 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02924141 0,0584111 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02924141 0,05836338 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02924141 0,05831573 ! macrophage differentiation GO:0030225 15 9 0,000 0,02924141 0,05826817 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02924141 0,05822068 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02924141 0,05817327 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02924141 0,05812593 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02924141 0,05807868 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02924141 0,0580315 ! response to amine stimulus GO:0014075 13 9 0,000 0,02924141 0,05798439 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02924141 0,05793737 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02924141 0,05789041 ! erythrocyte development GO:0048821 17 9 0,000 0,02924141 0,05784354 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02924141 0,05779674 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02924141 0,05775002 ! renal water homeostasis GO:0003091 15 9 0,000 0,02924141 0,05770337 ! postreplication repair GO:0006301 25 9 0,000 0,02924141 0,0576568 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02924141 0,0576103 ! icosanoid secretion GO:0032309 15 9 0,000 0,02924141 0,05756388 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02924141 0,05751753 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02924141 0,05747126 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02924141 0,05742506 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02924141 0,05737893 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02924141 0,05733288 ! sterol catabolic process GO:0016127 14 9 0,000 0,02924141 0,05728691 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02924141 0,057241 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02924141 0,05719517 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02924141 0,05714942 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02924141 0,05710373 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02924141 0,05705812 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02924141 0,05701259 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02924141 0,05696712 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02924141 0,05692173 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02924141 0,05687641 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02924141 0,05683116 ! purine base metabolic process GO:0006144 25 9 0,000 0,02924141 0,05678599 ! pigment granule transport GO:0051904 17 9 0,000 0,02924141 0,05674088 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02924141 0,05669585 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02924141 0,05665089 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02924141 0,056606 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02924141 0,05656118 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02924141 0,05651643 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02924141 0,05647176 ! mitochondrion localization GO:0051646 18 9 0,000 0,02924141 0,05642715 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,0307462 0,05928411 ! response to drug GO:0042493 149 83 1,000 0,0307462 0,05923735 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,0307462 0,05919067 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,03211893 0,06178468 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,03211893 0,06173607 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03243766 0,06229969 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03243766 0,06225076 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03243766 0,06220189 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03243766 0,06215311 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03243766 0,0621044 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03243766 0,06205576 ! associative learning GO:0008306 21 10 0,000 0,03243766 0,06200721 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03243766 0,06195873 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03243766 0,06191032 ! phosphate transport GO:0006817 24 10 0,000 0,03243766 0,06186199 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03243766 0,06181374 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03243766 0,06176556 ! CTP metabolic process GO:0046036 11 10 0,000 0,03243766 0,06171745 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03243766 0,06166943 ! GTP metabolic process GO:0046039 11 10 0,000 0,03243766 0,06162147 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03243766 0,06157359 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03243766 0,06152579 ! social behavior GO:0035176 29 10 0,000 0,03243766 0,06147805 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03243766 0,0614304 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03243766 0,06138281 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03243766 0,0613353 ! androgen metabolic process GO:0008209 17 10 0,000 0,03243766 0,06128787 ! phospholipid efflux GO:0033700 19 10 0,000 0,03243766 0,0612405 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03243766 0,06119321 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03243766 0,061146 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03243766 0,06109885 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03243766 0,06105178 ! pathogenesis GO:0009405 17 10 0,000 0,03243766 0,06100478 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03243766 0,06095785 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03243766 0,060911 ! endoderm development GO:0007492 18 10 0,000 0,03243766 0,06086422 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03243766 0,06081751 ! arginine catabolic process GO:0006527 17 10 0,000 0,03243766 0,06077087 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03243766 0,0607243 ! proline metabolic process GO:0006560 13 10 0,000 0,03243766 0,0606778 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03243766 0,06063138 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03243766 0,06058502 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03243766 0,06053874 ! V(D)J recombination GO:0033151 34 10 0,000 0,03243766 0,06049253 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03243766 0,06044639 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03243766 0,06040031 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03243766 0,06035431 ! B cell proliferation GO:0042100 19 10 0,000 0,03243766 0,06030838 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03243766 0,06026252 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03243766 0,06021673 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03243766 0,060171 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03243766 0,06012535 ! ruffle organization GO:0031529 17 10 0,000 0,03243766 0,06007977 ! epithelial cell development GO:0002064 21 10 0,000 0,03243766 0,06003425 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03243766 0,0599888 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03243766 0,05994343 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03243766 0,05989812 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03243766 0,05985288 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03243766 0,05980771 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03243766 0,0597626 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,03243766 0,05971757 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03243766 0,0596726 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03243766 0,0596277 ! brain morphogenesis GO:0048854 23 10 0,000 0,03243766 0,05958287 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03243766 0,0595381 ! segment specification GO:0007379 15 10 0,000 0,03243766 0,0594934 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03243766 0,05944877 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03243766 0,05940421 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03243766 0,05935971 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03243766 0,05931528 ! response to dsRNA GO:0043331 23 10 0,000 0,03243766 0,05927091 ! DNA ligation GO:0006266 18 10 0,000 0,03243766 0,05922662 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03243766 0,05918238 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03243766 0,05913822 ! melanosome localization GO:0032400 16 10 0,000 0,03243766 0,05909412 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03243766 0,05905008 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03243766 0,05900611 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03243766 0,05896221 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03243766 0,05891837 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03243766 0,0588746 ! induction of an organ GO:0001759 17 10 0,000 0,03243766 0,05883089 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03243766 0,05878725 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03243766 0,05874367 ! protein sumoylation GO:0016925 17 10 0,000 0,03243766 0,05870016 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03243766 0,05865671 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03243766 0,05861332 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03243766 0,05857 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03243766 0,05852674 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03243766 0,05848355 ! salivary gland development GO:0007431 28 10 0,000 0,03243766 0,05844042 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03243766 0,05839736 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03243766 0,05835435 ! midbrain development GO:0030901 14 10 0,000 0,03243766 0,05831141 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03243766 0,05826854 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03243766 0,05822572 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03243766 0,05818297 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03243766 0,05814029 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03243766 0,05809766 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03243766 0,0580551 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03243766 0,0580126 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03243766 0,05797016 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,03243766 0,05792779 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03243766 0,05788547 ! blastocyst formation GO:0001825 18 10 0,000 0,03243766 0,05784322 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03243766 0,05780103 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03243766 0,0577589 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03243766 0,05771683 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03243766 0,05767483 ! response to nicotine GO:0035094 20 10 0,000 0,03243766 0,05763288 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03243766 0,057591 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,03281423 0,05821726 ! regulation of lyase activity GO:0051339 169 86 1,000 0,03281423 0,05817502 ! mitochondrion organization GO:0007005 159 87 1,000 0,03351544 0,05937506 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,03493536 0,06184571 ! respiratory burst GO:0045730 17 11 0,000 0,03562348 0,06301822 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03562348 0,06297262 ! neuron fate specification GO:0048665 18 11 0,000 0,03562348 0,06292709 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03562348 0,06288162 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03562348 0,06283622 ! thyroid gland development GO:0030878 26 11 0,000 0,03562348 0,06279088 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,03562348 0,06274561 ! synapsis GO:0007129 14 11 0,000 0,03562348 0,0627004 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03562348 0,06265526 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03562348 0,06261019 ! response to pain GO:0048265 27 11 0,000 0,03562348 0,06256518 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03562348 0,06252023 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03562348 0,06247535 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03562348 0,06243053 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03562348 0,06238578 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03562348 0,06234109 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03562348 0,06229646 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03562348 0,0622519 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03562348 0,06220741 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03562348 0,06216297 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03562348 0,0621186 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03562348 0,06207429 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03562348 0,06203005 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03562348 0,06198587 ! UV protection GO:0009650 20 11 0,000 0,03562348 0,06194175 ! adult heart development GO:0007512 16 11 0,000 0,03562348 0,0618977 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03562348 0,0618537 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03562348 0,06180977 ! macroautophagy GO:0016236 19 11 0,000 0,03562348 0,06176591 ! temperature homeostasis GO:0001659 18 11 0,000 0,03562348 0,0617221 ! behavioral fear response GO:0001662 27 11 0,000 0,03562348 0,06167836 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03562348 0,06163467 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03562348 0,06159105 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03562348 0,0615475 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03562348 0,061504 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03562348 0,06146057 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03562348 0,06141719 ! regulation of organ growth GO:0046620 14 11 0,000 0,03562348 0,06137388 ! pigment granule localization GO:0051875 20 11 0,000 0,03562348 0,06133063 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03562348 0,06128744 ! vasoconstriction GO:0042310 20 11 0,000 0,03562348 0,06124431 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03562348 0,06120124 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03562348 0,06115823 ! embryonic axis specification GO:0000578 19 11 0,000 0,03562348 0,06111528 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03562348 0,06107239 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03562348 0,06102957 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03562348 0,0609868 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03562348 0,06094409 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03562348 0,06090144 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03562348 0,06085885 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03562348 0,06081632 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03562348 0,06077385 ! prophase GO:0051324 17 11 0,000 0,03562348 0,06073144 ! nucleosome positioning GO:0016584 15 11 0,000 0,03562348 0,06068909 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03562348 0,0606468 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03562348 0,06060457 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03562348 0,06056239 ! apical protein localization GO:0045176 18 11 0,000 0,03562348 0,06052028 ! acid secretion GO:0046717 20 11 0,000 0,03562348 0,06047822 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03562348 0,06043622 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03562348 0,06039428 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03562348 0,0603524 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03562348 0,06031058 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03562348 0,06026881 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03562348 0,0602271 ! cholesterol efflux GO:0033344 21 11 0,000 0,03562348 0,06018545 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03562348 0,06014386 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03562348 0,06010232 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03562348 0,06006084 ! embryonic gut development GO:0048566 19 11 0,000 0,03562348 0,06001942 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03562348 0,05997806 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03562348 0,05993675 ! activation of innate immune response GO:0002218 16 11 0,000 0,03562348 0,0598955 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03562348 0,05985431 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03562348 0,05981317 ! lysogeny GO:0030069 22 11 0,000 0,03562348 0,05977209 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03562348 0,05973106 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03562348 0,0596901 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03562348 0,05964918 ! nucleus localization GO:0051647 22 11 0,000 0,03562348 0,05960833 ! response to unfolded protein GO:0006986 139 90 1,000 0,03565398 0,05961853 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,03565398 0,05957775 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,03637832 0,06074658 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 1,000 0,03637832 0,06070509 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,03710834 0,06188101 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,03784398 0,0630647 ! vitamin metabolic process GO:0006766 153 93 1,000 0,03784398 0,06302171 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0387989 0,06456792 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0387989 0,06452396 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0387989 0,06448007 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0387989 0,06443623 ! virus-host interaction GO:0019048 30 12 0,000 0,0387989 0,06439246 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,0387989 0,06434874 ! mating GO:0007618 17 12 0,000 0,0387989 0,06430509 ! protein complex disassembly GO:0043241 28 12 0,000 0,0387989 0,06426149 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0387989 0,06421795 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0387989 0,06417448 ! T cell proliferation GO:0042098 32 12 0,000 0,0387989 0,06413106 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0387989 0,0640877 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0387989 0,06404439 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0387989 0,06400115 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0387989 0,06395796 ! drug transport GO:0015893 16 12 0,000 0,0387989 0,06391484 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0387989 0,06387177 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0387989 0,06382876 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0387989 0,0637858 ! focal adhesion formation GO:0048041 37 12 0,000 0,0387989 0,06374291 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0387989 0,06370007 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0387989 0,06365729 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0387989 0,06361456 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0387989 0,0635719 ! lipid digestion GO:0044241 21 12 0,000 0,0387989 0,06352929 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0387989 0,06348674 ! entry into host cell GO:0030260 34 12 0,000 0,0387989 0,06344424 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0387989 0,06340181 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0387989 0,06335943 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0387989 0,0633171 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0387989 0,06327483 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0387989 0,06323262 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0387989 0,06319047 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0387989 0,06314837 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0387989 0,06310633 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0387989 0,06306434 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0387989 0,06302241 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0387989 0,06298053 ! fucose catabolic process GO:0019317 25 12 0,000 0,0387989 0,06293871 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0387989 0,06289695 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0387989 0,06285524 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0387989 0,06281359 ! zymogen activation GO:0031638 18 12 0,000 0,0387989 0,06277199 ! T cell homeostasis GO:0043029 28 12 0,000 0,0387989 0,06273044 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0387989 0,06268896 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0387989 0,06264752 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0387989 0,06260614 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0387989 0,06256482 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0387989 0,06252355 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0387989 0,06248233 ! defense response to fungus GO:0050832 15 12 0,000 0,0387989 0,06244117 ! developmental induction GO:0031128 22 12 0,000 0,0387989 0,06240007 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0387989 0,06235901 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0387989 0,06231802 ! response to cold GO:0009409 17 12 0,000 0,0387989 0,06227707 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0387989 0,06223618 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0387989 0,06219534 ! localization within membrane GO:0051668 26 12 0,000 0,0387989 0,06215456 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,03933198 0,06296725 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,03933198 0,06292601 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,03933198 0,06288483 ! sex differentiation GO:0007548 171 96 1,000 0,04008424 0,06404565 ! response to protein stimulus GO:0051789 158 96 1,000 0,04008424 0,06400379 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,04084196 0,06517106 ! forebrain development GO:0030900 210 98 1,000 0,04160508 0,06634544 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,04160508 0,06630216 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04196394 0,06683045 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04196394 0,06678692 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04196394 0,06674344 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04196394 0,06670001 ! peroxisomal transport GO:0043574 28 13 0,000 0,04196394 0,06665664 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04196394 0,06661333 ! cartilage condensation GO:0001502 22 13 0,000 0,04196394 0,06657008 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04196394 0,06652688 ! organelle fusion GO:0048284 36 13 0,000 0,04196394 0,06648373 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04196394 0,06644065 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04196394 0,06639761 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04196394 0,06635464 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04196394 0,06631172 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04196394 0,06626885 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04196394 0,06622604 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04196394 0,06618329 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04196394 0,06614059 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04196394 0,06609795 ! methionine metabolic process GO:0006555 31 13 0,000 0,04196394 0,06605536 ! plasma membrane organization GO:0007009 27 13 0,000 0,04196394 0,06601282 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04196394 0,06597035 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04196394 0,06592792 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04196394 0,06588555 ! cytokine metabolic process GO:0042107 24 13 0,000 0,04196394 0,06584323 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,04196394 0,06580097 ! exocrine system development GO:0035272 34 13 0,000 0,04196394 0,06575877 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04196394 0,06571661 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04196394 0,06567451 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04196394 0,06563247 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,04196394 0,06559048 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,04196394 0,06554854 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04196394 0,06550666 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04196394 0,06546483 ! protein homotetramerization GO:0051289 24 13 0,000 0,04196394 0,06542305 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04196394 0,06538132 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04196394 0,06533965 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04196394 0,06529804 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04196394 0,06525647 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04196394 0,06521496 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04196394 0,0651735 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,04196394 0,06513209 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04196394 0,06509074 ! histone methylation GO:0016571 29 13 0,000 0,04196394 0,06504944 ! chromatin silencing GO:0006342 29 13 0,000 0,04196394 0,06500819 ! gland morphogenesis GO:0022612 31 13 0,000 0,04196394 0,06496699 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04196394 0,06492585 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04196394 0,06488476 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04196394 0,06484372 ! spleen development GO:0048536 24 13 0,000 0,04196394 0,06480273 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04196394 0,06476179 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04196394 0,06472091 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04196394 0,06468007 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04196394 0,06463929 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04196394 0,06459856 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04196394 0,06455788 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04196394 0,06451725 ! insulin secretion GO:0030073 24 13 0,000 0,04196394 0,06447668 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04196394 0,06443615 ! acrosome reaction GO:0007340 19 13 0,000 0,04196394 0,06439568 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04196394 0,06435525 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04196394 0,06431488 ! mRNA transport GO:0051028 185 100 1,000 0,04314738 0,06608719 ! rRNA transcription GO:0009303 28 14 0,000 0,04511866 0,06906321 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04511866 0,06901997 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,04511866 0,06897678 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04511866 0,06893364 ! non-recombinational repair GO:0000726 29 14 0,000 0,04511866 0,06889056 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04511866 0,06884753 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04511866 0,06880455 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04511866 0,06876163 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04511866 0,06871876 ! lipid localization GO:0010876 32 14 0,000 0,04511866 0,06867594 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04511866 0,06863318 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04511866 0,06859047 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04511866 0,06854782 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04511866 0,06850521 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04511866 0,06846266 ! arginine metabolic process GO:0006525 21 14 0,000 0,04511866 0,06842017 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04511866 0,06837772 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04511866 0,06833533 ! regulation of heart rate GO:0002027 25 14 0,000 0,04511866 0,06829299 ! fear response GO:0042596 34 14 0,000 0,04511866 0,0682507 ! organic alcohol transport GO:0015850 29 14 0,000 0,04511866 0,06820847 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04511866 0,06816629 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04511866 0,06812416 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04511866 0,06808208 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04511866 0,06804005 ! bone mineralization GO:0030282 18 14 0,000 0,04511866 0,06799808 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04511866 0,06795616 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04511866 0,06791429 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04511866 0,06787247 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04511866 0,0678307 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04511866 0,06778898 ! ribosome assembly GO:0042255 18 14 0,000 0,04511866 0,06774732 ! cerebellum development GO:0021549 23 14 0,000 0,04511866 0,06770571 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04511866 0,06766414 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04511866 0,06762263 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04511866 0,06758117 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04511866 0,06753976 ! NADP metabolic process GO:0006739 24 14 0,000 0,04511866 0,0674984 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04511866 0,06745709 ! oxygen transport GO:0015671 22 14 0,000 0,04511866 0,06741583 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04511866 0,06737463 ! male genitalia development GO:0030539 26 14 0,000 0,04511866 0,06733347 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04511866 0,06729236 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04511866 0,0672513 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04826308 0,07189433 ! lactation GO:0007595 30 15 0,000 0,04826308 0,07185052 ! reproductive cellular process GO:0048610 22 15 0,000 0,04826308 0,07180676 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04826308 0,07176305 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04826308 0,0717194 ! superoxide anion generation GO:0042554 22 15 0,000 0,04826308 0,0716758 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04826308 0,07163226 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04826308 0,07158877 ! copper ion transport GO:0006825 22 15 0,000 0,04826308 0,07154533 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04826308 0,07150194 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04826308 0,0714586 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04826308 0,07141532 ! sulfate transport GO:0008272 27 15 0,000 0,04826308 0,07137209 ! response to cAMP GO:0051591 25 15 0,000 0,04826308 0,07132892 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04826308 0,07128579 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04826308 0,07124272 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04826308 0,0711997 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04826308 0,07115673 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04826308 0,07111381 ! vesicle coating GO:0006901 38 15 0,000 0,04826308 0,07107094 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04826308 0,07102813 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04826308 0,07098537 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04826308 0,07094266 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04826308 0,0709 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04826308 0,07085739 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04826308 0,07081483 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04826308 0,07077233 ! histone deacetylation GO:0016575 24 15 0,000 0,04826308 0,07072987 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04826308 0,07068747 ! water homeostasis GO:0030104 28 15 0,000 0,04826308 0,07064512 ! cofactor transport GO:0051181 30 15 0,000 0,04826308 0,07060281 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04826308 0,07056056 ! muscle maintenance GO:0046716 26 15 0,000 0,04826308 0,07051836 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04826308 0,07047621 ! intestinal absorption GO:0050892 31 15 0,000 0,04826308 0,07043411 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04826308 0,07039206 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04826308 0,07035006 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04826308 0,07030811 ! cell killing GO:0001906 32 15 0,000 0,04826308 0,07026621 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04826308 0,07022436 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04826308 0,07018256 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04826308 0,07014081 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04826308 0,07009911 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04826308 0,07005746 ! actin filament polymerization GO:0030041 27 15 0,000 0,04826308 0,07001585 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04826308 0,0699743 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05139723 0,07447416 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05139723 0,07443001 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05139723 0,07438592 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05139723 0,07434187 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05139723 0,07429789 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05139723 0,07425395 ! bone remodeling GO:0046849 28 16 0,000 0,05139723 0,07421006 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05139723 0,07416623 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05139723 0,07412245 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05139723 0,07407872 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05139723 0,07403504 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05139723 0,07399141 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05139723 0,07394784 ! startle response GO:0001964 28 16 0,000 0,05139723 0,07390431 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05139723 0,07386084 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05139723 0,07381742 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05139723 0,07377405 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05139723 0,07373073 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05139723 0,07368746 ! pituitary gland development GO:0021983 30 16 0,000 0,05139723 0,07364424 ! response to osmotic stress GO:0006970 27 16 0,000 0,05139723 0,07360107 ! lysosomal transport GO:0007041 31 16 0,000 0,05139723 0,07355795 ! fructose metabolic process GO:0006000 25 16 0,000 0,05139723 0,07351489 ! L-amino acid transport GO:0015807 33 16 0,000 0,05139723 0,07347187 ! stem cell development GO:0048864 46 16 0,000 0,05139723 0,0734289 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05139723 0,07338599 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05139723 0,07334312 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05139723 0,07330031 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05139723 0,07325754 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05139723 0,07321483 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05139723 0,07317216 ! DNA replication initiation GO:0006270 28 16 0,000 0,05139723 0,07312954 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05139723 0,07308698 ! tissue regeneration GO:0042246 27 16 0,000 0,05139723 0,07304446 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05139723 0,07300199 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05139723 0,07295957 ! biomineral formation GO:0031214 22 16 0,000 0,05139723 0,0729172 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05139723 0,07287488 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05139723 0,07283261 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05139723 0,07279039 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05139723 0,07274822 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05139723 0,0727061 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05139723 0,07266402 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05139723 0,07262199 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,05139723 0,07258002 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05452114 0,07694694 ! metencephalon development GO:0022037 32 17 0,000 0,05452114 0,07690251 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05452114 0,07685814 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05452114 0,07681382 ! filopodium assembly GO:0046847 42 17 0,000 0,05452114 0,07676954 ! endothelial cell migration GO:0043542 31 17 0,000 0,05452114 0,07672532 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05452114 0,07668115 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05452114 0,07663703 ! glial cell development GO:0021782 28 17 0,000 0,05452114 0,07659296 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05452114 0,07654894 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05452114 0,07650497 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05452114 0,07646105 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05452114 0,07641719 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05452114 0,07637337 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05452114 0,0763296 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,05452114 0,07628589 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05452114 0,07624222 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05452114 0,0761986 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05452114 0,07615503 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05452114 0,07611152 GO:0031114|regulation of microtubule depolymerization, ! membrane budding GO:0006900 42 17 0,000 0,05452114 0,07606805 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05452114 0,07602463 ! regulation of protein binding GO:0043393 33 17 0,000 0,05452114 0,07598126 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05452114 0,07593795 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05452114 0,07589468 ! genitalia development GO:0048806 32 17 0,000 0,05452114 0,07585146 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,05452114 0,07580828 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05452114 0,07576516 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05452114 0,07572209 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05452114 0,07567907 ! steroid catabolic process GO:0006706 34 17 0,000 0,05452114 0,07563609 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05452114 0,07559316 ! gas transport GO:0015669 26 17 0,000 0,05452114 0,07555029 ! organic cation transport GO:0015695 32 17 0,000 0,05452114 0,07550746 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05452114 0,07546468 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05452114 0,07542195 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,05763486 0,07968419 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05763486 0,07963912 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05763486 0,0795941 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05763486 0,07954913 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05763486 0,07950422 ! adult walking behavior GO:0007628 36 18 0,000 0,05763486 0,07945935 ! heart looping GO:0001947 34 18 0,000 0,05763486 0,07941453 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05763486 0,07936977 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05763486 0,07932505 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05763486 0,07928039 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05763486 0,07923577 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05763486 0,07919121 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05763486 0,07914669 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,05763486 0,07910223 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,05763486 0,07905781 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05763486 0,07901345 ! DNA integration GO:0015074 32 18 0,000 0,05763486 0,07896913 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05763486 0,07892487 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05763486 0,07888065 ! neural crest cell migration GO:0001755 41 18 0,000 0,05763486 0,07883649 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05763486 0,07879237 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05763486 0,0787483 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05763486 0,07870429 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05763486 0,07866032 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05763486 0,0786164 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05763486 0,07857253 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,05763486 0,0785287 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05763486 0,07848493 ! defense response to virus GO:0051607 43 18 0,000 0,05763486 0,07844121 ! microspike assembly GO:0030035 46 18 0,000 0,05763486 0,07839753 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05763486 0,0783539 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,05763486 0,07831033 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06073841 0,08248134 ! positive regulation of translation GO:0045727 31 19 0,000 0,06073841 0,08243552 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06073841 0,08238975 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,06073841 0,08234403 ! neuron maturation GO:0042551 46 19 0,000 0,06073841 0,08229836 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,06073841 0,08225274 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,06073841 0,08220717 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06073841 0,08216165 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06073841 0,08211618 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06073841 0,08207076 ! inositol metabolic process GO:0006020 33 19 0,000 0,06073841 0,08202539 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06073841 0,08198008 ! memory GO:0007613 34 19 0,000 0,06073841 0,08193481 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06073841 0,08188959 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06073841 0,08184442 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06073841 0,0817993 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,06073841 0,08175424 ! cerebral cortex development GO:0021987 40 19 0,000 0,06073841 0,08170922 ! heme metabolic process GO:0042168 40 19 0,000 0,06073841 0,08166425 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06073841 0,08161933 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06073841 0,08157446 ! response to fungus GO:0009620 26 19 0,000 0,06073841 0,08152964 ! peptide cross-linking GO:0018149 39 19 0,000 0,06073841 0,08148487 ! protein export from nucleus GO:0006611 40 19 0,000 0,06073841 0,08144014 ! heart process GO:0003015 32 19 0,000 0,06073841 0,08139547 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06073841 0,08135084 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06073841 0,08130627 ! visual learning GO:0008542 38 19 0,000 0,06073841 0,08126174 ! cellular pigmentation GO:0033059 37 19 0,000 0,06073841 0,08121726 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06073841 0,08117283 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06073841 0,08112845 ! vitamin transport GO:0051180 31 19 0,000 0,06073841 0,08108412 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06073841 0,08103984 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06073841 0,0809956 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,06073841 0,08095141 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06073841 0,08090727 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06073841 0,08086318 ! cilium assembly GO:0042384 38 19 0,000 0,06073841 0,08081914 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06073841 0,08077514 ! protein secretion GO:0009306 45 20 0,000 0,06383183 0,08484285 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06383183 0,08479671 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06383183 0,08475063 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06383183 0,08470459 ! skin development GO:0043588 42 20 0,000 0,06383183 0,08465861 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06383183 0,08461267 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06383183 0,08456679 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06383183 0,08452095 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06383183 0,08447517 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,06383183 0,08442943 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,06383183 0,08438374 ! response to alkaloid GO:0043279 38 20 0,000 0,06383183 0,0843381 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06383183 0,08429252 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,06383183 0,08424698 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06383183 0,08420149 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,06383183 0,08415605 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,06383183 0,08411066 ! body fluid secretion GO:0007589 33 20 0,000 0,06383183 0,08406531 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06383183 0,08402002 ! peptide secretion GO:0002790 38 20 0,000 0,06383183 0,08397477 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06383183 0,08392958 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06383183 0,08388443 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06383183 0,08383933 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06383183 0,08379428 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06383183 0,08374928 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06383183 0,08370432 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06383183 0,08365942 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06383183 0,08361456 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06383183 0,08356975 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,06383183 0,08352499 ! regulation of glucose import GO:0046324 30 20 0,000 0,06383183 0,08348028 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,06383183 0,08343561 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06383183 0,08339099 ! negative regulation of translation GO:0017148 32 20 0,000 0,06383183 0,08334642 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06383183 0,0833019 ! regulation of cell killing GO:0031341 46 21 0,000 0,06691514 0,08727907 ! hormone secretion GO:0046879 39 21 0,000 0,06691514 0,08723249 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06691514 0,08718597 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,06691514 0,0871395 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06691514 0,08709307 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06691514 0,08704669 ! ovarian follicle development GO:0001541 39 21 0,000 0,06691514 0,08700037 ! smooth muscle contraction GO:0006939 48 21 0,000 0,06691514 0,08695409 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,06691514 0,08690786 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06691514 0,08686169 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,06691514 0,08681556 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06691514 0,08676948 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,06691514 0,08672344 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,06691514 0,08667746 ! sensory perception of pain GO:0019233 33 21 0,000 0,06691514 0,08663153 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06691514 0,08658564 ! diencephalon development GO:0021536 36 21 0,000 0,06691514 0,08653981 ! collagen fibril organization GO:0030199 62 21 0,000 0,06691514 0,08649402 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,06691514 0,08644828 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06691514 0,08640259 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,06691514 0,08635694 ! collagen catabolic process GO:0030574 29 21 0,000 0,06691514 0,08631135 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06691514 0,0862658 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06691514 0,0862203 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06691514 0,08617485 ! actin filament-based movement GO:0030048 47 21 0,000 0,06691514 0,08612945 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06998839 0,09003772 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06998839 0,08999033 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06998839 0,089943 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06998839 0,08989571 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06998839 0,08984847 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,06998839 0,08980128 ! vacuolar transport GO:0007034 41 22 0,000 0,06998839 0,08975414 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06998839 0,08970705 ! fucose metabolic process GO:0006004 44 22 0,000 0,06998839 0,08966001 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06998839 0,08961302 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06998839 0,08956607 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06998839 0,08951918 ! ureteric bud development GO:0001657 50 22 0,000 0,06998839 0,08947234 ! stem cell differentiation GO:0048863 57 22 0,000 0,06998839 0,08942554 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06998839 0,08937879 ! cytolysis GO:0019835 27 22 0,000 0,06998839 0,0893321 ! renal system process GO:0003014 42 22 0,000 0,06998839 0,08928545 ! vasodilation GO:0042311 40 22 0,000 0,06998839 0,08923885 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06998839 0,0891923 ! G1 phase GO:0051318 44 22 0,000 0,06998839 0,08914579 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06998839 0,08909934 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06998839 0,08905293 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06998839 0,08900658 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06998839 0,08896027 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06998839 0,08891401 ! sarcomere organization GO:0045214 32 22 0,000 0,06998839 0,08886779 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,06998839 0,08882163 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06998839 0,08877551 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06998839 0,08872944 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06998839 0,08868342 ! gut development GO:0048565 44 22 0,000 0,06998839 0,08863745 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06998839 0,08859152 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06998839 0,08854564 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06998839 0,08849981 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,0730516 0,09232543 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0730516 0,09227769 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0730516 0,09223 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0730516 0,09218236 ! gluconeogenesis GO:0006094 38 23 0,000 0,0730516 0,09213477 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0730516 0,09208723 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0730516 0,09203974 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0730516 0,0919923 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0730516 0,0919449 ! regeneration GO:0031099 42 23 0,000 0,0730516 0,09189756 ! axis specification GO:0009798 43 23 0,000 0,0730516 0,09185026 ! visual behavior GO:0007632 46 23 0,000 0,0730516 0,09180301 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,0730516 0,09175581 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0730516 0,09170866 ! response to ethanol GO:0045471 47 23 0,000 0,0730516 0,09166156 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0730516 0,09161451 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,0730516 0,0915675 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0730516 0,09152054 ! peroxisome organization GO:0007031 43 23 0,000 0,0730516 0,09147363 ! lysosome organization GO:0007040 47 23 0,000 0,0730516 0,09142677 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,0730516 0,09137996 ! vesicle targeting GO:0006903 49 23 0,000 0,0730516 0,09133319 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,0730516 0,09128647 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0730516 0,0912398 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0730516 0,09119318 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0730516 0,09114661 ! DNA modification GO:0006304 36 23 0,000 0,0730516 0,09110008 ! fatty acid transport GO:0015908 47 23 0,000 0,0730516 0,0910536 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,0730516 0,09100717 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,0730516 0,09096078 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0730516 0,09091445 ! hormone transport GO:0009914 41 23 0,000 0,0730516 0,09086816 ! cell-cell recognition GO:0009988 28 23 0,000 0,0730516 0,09082191 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,0730516 0,09077572 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0730516 0,09072957 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0730516 0,09068346 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,07610481 0,09442562 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,07610481 0,09437769 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,07610481 0,0943298 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,07610481 0,09428197 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,07610481 0,09423418 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,07610481 0,09418644 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,07610481 0,09413875 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,07610481 0,09409111 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,07610481 0,09404352 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,07610481 0,09399598 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,07610481 0,09394848 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,07610481 0,09390103 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,07610481 0,09385363 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,07610481 0,09380628 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,07610481 0,09375897 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,07610481 0,09371171 ! sex determination GO:0007530 48 24 0,000 0,07610481 0,0936645 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,07610481 0,09361734 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,07610481 0,09357023 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,07610481 0,09352316 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,07610481 0,09347614 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,07610481 0,09342917 ! membrane depolarization GO:0051899 45 24 0,000 0,07610481 0,09338224 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,07610481 0,09333536 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,07610481 0,09328853 ! platelet activation GO:0030168 41 24 0,000 0,07610481 0,09324175 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,07610481 0,09319501 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,07610481 0,09314832 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,07610481 0,09310167 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,07610481 0,09305508 ! regulation of amine transport GO:0051952 41 24 0,000 0,07610481 0,09300852 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,07914804 0,09667933 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,07914804 0,09663102 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,07914804 0,09658275 ! leukocyte adhesion GO:0007159 55 25 0,000 0,07914804 0,09653453 ! phototransduction GO:0007602 37 25 0,000 0,07914804 0,09648636 ! keratinization GO:0031424 37 25 0,000 0,07914804 0,09643824 ! vacuole organization GO:0007033 49 25 0,000 0,07914804 0,09639016 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,07914804 0,09634214 ! chromosome condensation GO:0030261 48 25 0,000 0,07914804 0,09629416 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,07914804 0,09624623 ! interaction with host GO:0051701 66 25 0,000 0,07914804 0,09619834 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,07914804 0,09615051 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,07914804 0,09610272 ! immunoglobulin production GO:0002377 62 25 0,000 0,07914804 0,09605498 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,07914804 0,09600728 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,07914804 0,09595964 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,07914804 0,09591204 ! liver development GO:0001889 55 25 0,000 0,07914804 0,09586448 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08218134 0,0994891 ! myelination GO:0042552 50 26 0,000 0,08218134 0,09943983 ! initiation of viral infection GO:0019059 60 26 0,000 0,08218134 0,0993906 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,08218134 0,09934142 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08218134 0,09929229 ! molting cycle process GO:0022404 52 26 0,000 0,08218134 0,09924321 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08218134 0,09919418 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,08218134 0,09914519 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,08218134 0,09909625 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08218134 0,09904737 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08218134 0,09899853 ! digestive system process GO:0022600 49 26 0,000 0,08218134 0,09894973 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08218134 0,09890099 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08218134 0,09885229 ! osteoblast differentiation GO:0001649 63 26 0,000 0,08218134 0,09880365 ! neural crest cell development GO:0014032 59 26 0,000 0,08218134 0,09875505 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08218134 0,0987065 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,08218134 0,09865799 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08218134 0,09860953 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08218134 0,09856112 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08218134 0,09851276 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08218134 0,09846445 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08218134 0,09841618 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08218134 0,09836796 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,08218134 0,09831979 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,08218134 0,09827166 ! telomere organization GO:0032200 46 26 0,000 0,08218134 0,09822359 GO:0000723|telomere maintenance, ! alditol metabolic process GO:0019400 44 26 0,000 0,08218134 0,09817556 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08218134 0,09812757 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08218134 0,09807963 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,08520473 0,10163826 ! embryonic pattern specification GO:0009880 49 27 0,000 0,08520473 0,10158865 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,08520473 0,1015391 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,08520473 0,10148959 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,08520473 0,10144013 ! iron ion transport GO:0006826 65 27 0,000 0,08520473 0,10139072 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,08520473 0,10134136 ! superoxide metabolic process GO:0006801 41 27 0,000 0,08520473 0,10129205 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,08520473 0,10124278 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,08520473 0,10119356 ! response to toxin GO:0009636 49 27 0,000 0,08520473 0,10114439 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,08520473 0,10109527 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,08520473 0,10104619 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,08520473 0,10099716 ! leukocyte proliferation GO:0070661 59 27 0,000 0,08520473 0,10094818 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,08520473 0,10089925 ! neuron fate commitment GO:0048663 52 28 0,000 0,08821825 0,10441724 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,08821825 0,10436667 ! vesicle docking GO:0048278 55 28 0,000 0,08821825 0,10431615 ! circadian rhythm GO:0007623 56 28 0,000 0,08821825 0,10426569 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,08821825 0,10421527 ! fat cell differentiation GO:0045444 57 28 0,000 0,08821825 0,1041649 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,08821825 0,10411458 ! sperm motility GO:0030317 37 28 0,000 0,08821825 0,1040643 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,08821825 0,10401408 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,08821825 0,1039639 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,08821825 0,10391378 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,08821825 0,1038637 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,08821825 0,10381367 ! glutathione metabolic process GO:0006749 42 28 0,000 0,08821825 0,10376368 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,08821825 0,10371375 ! lipid oxidation GO:0034440 48 28 0,000 0,08821825 0,10366386 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,08821825 0,10361403 ! translational initiation GO:0006413 66 29 0,000 0,09122192 0,10709041 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,09122192 0,10703898 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,09122192 0,10698759 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,09122192 0,10693625 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,09122192 0,10688496 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,09122192 0,10683372 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,09122192 0,10678253 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,09122192 0,10673139 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,09122192 0,1066803 ! synaptogenesis GO:0007416 46 29 0,000 0,09122192 0,10662926 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,09122192 0,10657826 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,09122192 0,10652732 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,09122192 0,10647642 ! phenol metabolic process GO:0018958 56 30 0,000 0,09421578 0,10991841 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,09421578 0,10986594 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,09421578 0,10981353 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,09421578 0,10976116 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,09421578 0,10970884 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,09421578 0,10965658 ! acute-phase response GO:0006953 50 30 0,000 0,09421578 0,10960436 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,09421578 0,10955219 ! myofibril assembly GO:0030239 50 30 0,000 0,09421578 0,10950007 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,09421578 0,109448 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,09421578 0,10939599 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,09421578 0,10934402 ! cell fate determination GO:0001709 64 30 0,000 0,09421578 0,1092921 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,09421578 0,10924023 ! phospholipid transport GO:0015914 65 30 0,000 0,09421578 0,1091884 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,09421578 0,10913663 ! neurotransmitter secretion GO:0007269 55 30 0,000 0,09421578 0,10908491 ! regulation of B cell activation GO:0050864 55 30 0,000 0,09421578 0,10903323 ! regulation of coagulation GO:0050818 52 30 0,000 0,09421578 0,10898161 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,09719987 0,11238016 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,09719987 0,112327 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,09719987 0,11227389 ! cell junction assembly GO:0034329 85 31 0,000 0,09719987 0,11222083 ! regulation of innate immune response GO:0045088 57 31 0,000 0,09719987 0,11216782 ! ovulation cycle process GO:0022602 55 31 0,000 0,09719987 0,11211486 ! peptide transport GO:0015833 60 31 0,000 0,09719987 0,11206195 ! male gonad development GO:0008584 56 31 0,000 0,09719987 0,11200909 ! iron ion homeostasis GO:0055072 60 31 0,000 0,09719987 0,11195628 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,09719987 0,11190352 ! detection of light stimulus GO:0009583 44 31 0,000 0,09719987 0,11185081 ! natural killer cell activation GO:0030101 50 31 0,000 0,09719987 0,11179815 ! ensheathment of neurons GO:0007272 64 31 0,000 0,09719987 0,11174554 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,09719987 0,11169298 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,09719987 0,11164047 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,09719987 0,111588 ! eye morphogenesis GO:0048592 65 31 0,000 0,09719987 0,11153559 ! response to heat GO:0009408 54 31 0,000 0,09719987 0,11148323 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,09719987 0,11143091 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,1001742 0,11478686 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1001742 0,11473304 ! collagen metabolic process GO:0032963 49 32 0,000 0,1001742 0,11467928 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1001742 0,11462556 ! spindle organization GO:0007051 50 32 0,000 0,1001742 0,1145719 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,1001742 0,11451829 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1001742 0,11446472 ! metanephros development GO:0001656 81 32 0,000 0,1001742 0,11441121 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,1001742 0,11435775 ! muscle cell development GO:0055001 52 32 0,000 0,1001742 0,11430433 ! mesoderm formation GO:0001707 73 32 0,000 0,1001742 0,11425097 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,1001742 0,11419766 ! ovulation cycle GO:0042698 57 32 0,000 0,1001742 0,11414439 ! peripheral nervous system development GO:0007422 68 32 0,000 0,1001742 0,11409118 ! BMP signaling pathway GO:0030509 71 32 0,000 0,1001742 0,11403801 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1001742 0,1139849 ! gene silencing GO:0016458 71 32 0,000 0,1001742 0,11393183 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,10313882 0,11724902 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,10313882 0,11719449 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,10313882 0,11714 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,10313882 0,11708557 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,10313882 0,11703119 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,10313882 0,11697685 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,10313882 0,11692257 GO:0060326|cell chemotaxis, ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,10313882 0,11686834 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,10313882 0,11681416 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,10609376 0,12010522 ! post-embryonic development GO:0009791 76 34 0,000 0,10609376 0,12004959 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,10609376 0,11999401 ! cholesterol transport GO:0030301 62 34 0,000 0,10609376 0,11993848 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,10609376 0,119883 ! spliceosome assembly GO:0000245 75 34 0,000 0,10609376 0,11982758 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,10609376 0,11977221 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,10609376 0,11971688 ! formation of primary germ layer GO:0001704 76 34 0,000 0,10609376 0,11966161 ! cell fate specification GO:0001708 56 34 0,000 0,10609376 0,11960639 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,10609376 0,11955122 ! adult locomotory behavior GO:0008344 62 34 0,000 0,10609376 0,11949611 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,10609376 0,11944104 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,10903904 0,12270031 ! negative regulation of secretion GO:0051048 68 35 0,000 0,10903904 0,12264382 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,10903904 0,12258738 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,10903904 0,122531 ! membrane docking GO:0022406 69 35 0,000 0,10903904 0,12247466 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,10903904 0,12241837 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,10903904 0,12236214 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,10903904 0,12230596 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,10903904 0,12224983 ! ceramide metabolic process GO:0006672 72 35 0,000 0,10903904 0,12219375 ! sterol transport GO:0015918 63 35 0,000 0,10903904 0,12213773 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,10903904 0,12208175 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,10903904 0,12202583 ! placenta development GO:0001890 53 35 0,000 0,10903904 0,12196996 ! vesicle localization GO:0051648 70 35 0,000 0,10903904 0,12191413 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,11197471 0,12513916 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,11197471 0,12508194 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,11197471 0,12502477 ! positive regulation of cell development GO:0010720 85 36 0,000 0,11197471 0,12496766 ! protein targeting to membrane GO:0006612 75 36 0,000 0,11197471 0,1249106 ! regulation of proteolysis GO:0030162 77 36 0,000 0,11197471 0,12485359 ! aerobic respiration GO:0009060 56 36 0,000 0,11197471 0,12479663 ! cytokine production GO:0001816 68 36 0,000 0,11197471 0,12473972 ! embryonic organ development GO:0048568 67 36 0,000 0,11197471 0,12468287 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,11197471 0,12462606 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,11197471 0,12456931 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,11490078 0,12776632 ! sister chromatid segregation GO:0000819 65 37 0,000 0,11490078 0,12770819 ! odontogenesis GO:0042476 74 37 0,000 0,11490078 0,12765011 ! actomyosin structure organization GO:0031032 68 37 0,000 0,11490078 0,12759209 ! cell junction organization GO:0034330 96 37 0,000 0,11490078 0,12753412 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,11490078 0,1274762 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,11490078 0,12741834 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,11781729 0,1305933 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,11781729 0,13053408 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,11781729 0,1304749 ! organic anion transport GO:0015711 82 38 0,000 0,11781729 0,13041579 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,11781729 0,13035672 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,11781729 0,13029771 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,11781729 0,13023875 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,11781729 0,13017985 ! spermatid development GO:0007286 69 38 0,000 0,11781729 0,13012099 ! pigment metabolic process GO:0042440 87 38 0,000 0,11781729 0,1300622 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,12072427 0,13321111 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,12072427 0,13315097 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,12072427 0,13309089 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,12072427 0,13303085 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,12072427 0,13297088 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,12072427 0,13291095 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,12072427 0,13285108 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,12362176 0,13597837 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,12362176 0,13591717 ! learning GO:0007612 82 40 0,000 0,12362176 0,13585603 ! nucleus organization GO:0006997 73 40 0,000 0,12362176 0,13579495 ! lipid homeostasis GO:0055088 75 40 0,000 0,12362176 0,13573392 ! mismatch repair GO:0006298 58 40 0,000 0,12362176 0,13567294 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,12362176 0,13561202 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,12362176 0,13555115 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,12362176 0,13549034 ! RNA export from nucleus GO:0006405 61 41 0,000 0,12650978 0,13859345 ! mRNA catabolic process GO:0006402 79 41 0,000 0,12650978 0,13853133 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,12650978 0,13846926 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,12650978 0,13840725 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,12650978 0,1383453 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,12650978 0,1382834 ! feeding behavior GO:0007631 69 41 0,000 0,12650978 0,13822155 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,12650978 0,13815976 ! mesenchymal cell development GO:0014031 94 41 0,000 0,12650978 0,13809803 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,12650978 0,13803635 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,12650978 0,13797473 ! RNA modification GO:0009451 64 41 0,000 0,12650978 0,13791316 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,12938836 0,1409883 ! ear morphogenesis GO:0042471 64 42 0,000 0,12938836 0,14092545 ! organic ether metabolic process GO:0018904 59 42 0,000 0,12938836 0,14086264 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,12938836 0,1407999 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,12938836 0,14073721 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,12938836 0,14067458 ! regulation of protein secretion GO:0050708 77 42 0,000 0,12938836 0,140612 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,13225754 0,14366615 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,13225754 0,1436023 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,13225754 0,14353851 ! regulation of tube size GO:0035150 76 43 0,000 0,13225754 0,14347477 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,13225754 0,14341109 ! glucose transport GO:0015758 66 43 0,000 0,13225754 0,14334746 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,13225754 0,14328389 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,13225754 0,14322038 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,13225754 0,14315692 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,13225754 0,14309352 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,13225754 0,14303018 ! ion transmembrane transport GO:0034220 79 43 0,000 0,13225754 0,14296689 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,13225754 0,14290366 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,13511735 0,14592912 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,13511735 0,14586464 ! hexose transport GO:0008645 68 44 0,000 0,13511735 0,14580021 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,13511735 0,14573584 ! striated muscle contraction GO:0006941 85 44 0,000 0,13511735 0,14567152 ! phagocytosis GO:0006909 105 44 0,000 0,13511735 0,14560727 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,13511735 0,14554307 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,1379678 0,14854797 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1379678 0,14848253 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,1379678 0,14841715 ! polyol metabolic process GO:0019751 77 45 0,000 0,1379678 0,14835182 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,14080895 0,15134019 ! glycolysis GO:0006096 71 46 0,000 0,14080895 0,15127364 ! leukocyte migration GO:0050900 75 46 0,000 0,14080895 0,15120715 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,14080895 0,15114071 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,14364081 0,15411264 ! positive regulation of defense response GO:0031349 88 48 0,000 0,14646341 0,15707204 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,14646341 0,15700312 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,14646341 0,15693426 ! cellular component disassembly GO:0022411 89 48 0,000 0,14646341 0,15686546 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,14646341 0,15679672 ! male sex differentiation GO:0046661 93 48 0,000 0,14646341 0,15672804 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,14646341 0,15665942 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,14646341 0,15659086 ! methylation GO:0032259 97 48 0,000 0,14646341 0,15652236 ! response to calcium ion GO:0051592 94 49 0,000 0,14927679 0,15945921 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,14927679 0,15938951 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,14927679 0,15931988 ! JNK cascade GO:0007254 106 49 0,000 0,14927679 0,15925031 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,14927679 0,1591808 ! regulation of action potential GO:0001508 102 50 0,000 0,15208098 0,16210028 ! regulation of ion transport GO:0043269 86 50 0,000 0,15208098 0,16202958 ! endocrine system development GO:0035270 109 50 0,000 0,15208098 0,16195895 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,15208098 0,16188838 ! regulation of ossification GO:0030278 123 50 0,000 0,15208098 0,16181787 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,15208098 0,16174743 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,15208098 0,16167704 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,15208098 0,16160671 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,15208098 0,16153645 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,154876 0,16443376 ! peptide metabolic process GO:0006518 80 51 0,000 0,154876 0,16436233 ! response to temperature stimulus GO:0009266 84 51 0,000 0,154876 0,16429096 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,154876 0,16421965 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,154876 0,16414841 ! Notch signaling pathway GO:0007219 111 52 0,000 0,15766189 0,16702862 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,15766189 0,16695622 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,15766189 0,16688388 ! excretion GO:0007588 87 52 0,000 0,15766189 0,16681161 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,15766189 0,16673939 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,15766189 0,16666724 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,16043867 0,16952927 ! positive regulation of growth GO:0045927 96 53 0,000 0,16043867 0,16945598 ! inner ear development GO:0048839 89 53 0,000 0,16043867 0,16938275 ! vesicle organization GO:0016050 127 53 0,000 0,16043867 0,16930958 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,16043867 0,16923648 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,16043867 0,16916343 ! synapse organization GO:0050808 102 53 0,000 0,16043867 0,16909046 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,16320638 0,17193324 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,16320638 0,17185913 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,16320638 0,17178509 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,16320638 0,1717111 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,16320638 0,17163719 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,16320638 0,17156333 ! RNA catabolic process GO:0006401 103 55 0,000 0,16596504 0,17438821 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,16596504 0,17431324 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,16596504 0,17423833 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,16596504 0,17416348 ! glucose catabolic process GO:0006007 88 56 0,000 0,16871468 0,17697294 ! RNA elongation GO:0006354 90 56 0,000 0,16871468 0,17689698 ! chloride transport GO:0006821 102 57 0,000 0,17145534 0,17969343 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,17145534 0,17961638 ! heart morphogenesis GO:0003007 105 57 0,000 0,17145534 0,17953939 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,17418704 0,18232173 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,17418704 0,18224365 ! gastrulation GO:0007369 122 58 0,000 0,17418704 0,18216564 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,17418704 0,18208769 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,17418704 0,18200981 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,17418704 0,18193199 ! nuclear export GO:0051168 110 59 0,000 0,1769098 0,18469686 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1769098 0,18461796 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,17962367 0,18737004 ! DNA catabolic process GO:0006308 94 60 0,000 0,17962367 0,18729007 ! regulation of endocytosis GO:0030100 104 60 0,000 0,17962367 0,18721016 ! adult behavior GO:0030534 104 60 0,000 0,17962367 0,18713033 ! kidney development GO:0001822 133 60 0,000 0,17962367 0,18705056 ! positive regulation of secretion GO:0051047 110 61 0,000 0,18232866 0,1897865 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,18232866 0,18970568 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,18232866 0,18962492 ! regulation of heart contraction GO:0008016 123 61 0,000 0,18232866 0,18954422 ! camera-type eye development GO:0043010 126 61 0,000 0,18232866 0,1894636 ! proton transport GO:0015992 117 61 0,000 0,18232866 0,18938305 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,18232866 0,18930256 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,18502482 0,19202023 ! tRNA processing GO:0008033 102 62 0,000 0,18502482 0,19193869 ! regulation of mitosis GO:0007088 112 63 0,000 0,18771215 0,1946438 GO:0051783|regulation of nuclear division, ! hydrogen transport GO:0006818 121 64 0,000 0,1903907 0,1973375 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,1903907 0,19725381 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1930605 0,19993506 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,1930605 0,19985034 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,1930605 0,19976569 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1930605 0,19968112 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1930605 0,19959661 ! ear development GO:0043583 114 66 0,000 0,19572156 0,20226217 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,19572156 0,20217665 ! activation of MAPK activity GO:0000187 124 67 0,000 0,19837393 0,20482988 ! chromosome segregation GO:0007059 127 67 0,000 0,19837393 0,20474335 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,19837393 0,20465688 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,19837393 0,2045705 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,20101762 0,2072093 ! hexose catabolic process GO:0019320 113 68 0,000 0,20101762 0,20712191 ! extracellular matrix organization GO:0030198 146 68 0,000 0,20101762 0,20703459 ! regulation of lipase activity GO:0060191 137 68 0,000 0,20101762 0,20694734 ! cell projection assembly GO:0030031 138 68 0,000 0,20101762 0,20686017 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,20365267 0,20948356 ! urogenital system development GO:0001655 149 69 0,000 0,20365267 0,2093954 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,20365267 0,2093073 ! single fertilization GO:0007338 83 69 0,000 0,20365267 0,20921929 ! cell redox homeostasis GO:0045454 114 70 0,000 0,2062791 0,21182843 ! activation of immune response GO:0002253 120 70 0,000 0,2062791 0,21173943 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,2062791 0,2116505 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,20889694 0,21424653 ! carbohydrate transport GO:0008643 114 72 0,000 0,21150622 0,2168316 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,21150622 0,21674065 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,21150622 0,21664977 ! humoral immune response GO:0006959 115 73 0,000 0,21410697 0,21922185 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,21410697 0,21913001 ! regulation of immune effector process GO:0002697 156 73 0,000 0,21410697 0,21903824 ! acute inflammatory response GO:0002526 118 74 0,000 0,21669921 0,2215974 ! amino acid transport GO:0006865 148 74 0,000 0,21669921 0,22150468 ! organelle localization GO:0051640 155 74 0,000 0,21669921 0,22141204 ! transition metal ion transport GO:0000041 143 75 0,000 0,21928298 0,22395833 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,21928298 0,22386474 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,21928298 0,22377123 ! eye development GO:0001654 155 75 0,000 0,21928298 0,2236778 ! rhythmic process GO:0048511 142 75 0,000 0,21928298 0,22358444 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,2218583 0,2261159 ! regulation of blood pressure GO:0008217 134 76 0,000 0,2218583 0,22602161 ! neurotransmitter transport GO:0006836 142 77 0,000 0,22442519 0,22854137 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,22442519 0,22844614 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,22442519 0,228351 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,22442519 0,22825593 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,22698369 0,23076203 ! fertilization GO:0009566 99 78 0,000 0,22698369 0,23066604 ! blood coagulation GO:0007596 151 79 0,000 0,22953382 0,23316055 GO:0050817|coagulation, ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,22953382 0,23306364 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,23460908 0,23811798 ! exocytosis GO:0006887 153 83 0,000 0,2396512 0,2431345 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2396512 0,24303357 ! inorganic anion transport GO:0015698 156 83 0,000 0,2396512 0,24293273 ! response to metal ion GO:0010038 158 84 0,000 0,24215989 0,24537396 ! digestion GO:0007586 130 84 0,000 0,24215989 0,24527223 ! hemostasis GO:0007599 165 85 0,000 0,24466038 0,24770216 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,24466038 0,24759955 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,24466038 0,24749702 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,24963684 0,25242666 ! alcohol catabolic process GO:0046164 142 87 0,000 0,24963684 0,25232222 ! nucleosome assembly GO:0006334 126 87 0,000 0,24963684 0,25221787 ! cellular respiration GO:0045333 143 88 0,000 0,25211287 0,2546142 ! amine biosynthetic process GO:0009309 146 88 0,000 0,25211287 0,25450898 ! sensory perception of smell GO:0007608 117 88 0,000 0,25211287 0,25440386 ! chromatin assembly GO:0031497 128 88 0,000 0,25211287 0,25429882 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,25211287 0,25419387 ! cellular defense response GO:0006968 123 89 0,000 0,25458079 0,25657627 ! regulation of neurological system process GO:0031644 175 89 0,000 0,25458079 0,25647047 ! response to inorganic substance GO:0010035 173 90 0,000 0,25704065 0,25884184 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,25704065 0,25873519 ! ossification GO:0001503 205 91 0,000 0,25949245 0,26109558 ! defense response to bacterium GO:0042742 112 91 0,000 0,25949245 0,26098808 ! bone development GO:0060348 206 92 0,000 0,26193623 0,26333754 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,26193623 0,26322921 ! amine transport GO:0015837 181 93 0,000 0,26437202 0,26556778 ! female pregnancy GO:0007565 166 94 0,000 0,26679983 0,26789642 ! sterol metabolic process GO:0016125 166 94 0,000 0,26679983 0,26778636 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,26679983 0,26767638 ! regulation of membrane potential GO:0042391 179 94 0,000 0,26679983 0,2675665 ! regulation of defense response GO:0031347 171 95 0,000 0,2692197 0,26988253 ! nucleosome organization GO:0034728 143 95 0,000 0,2692197 0,26977184 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,2692197 0,26966123 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,2692197 0,26955071 ! transcription initiation GO:0006352 171 97 0,000 0,27403571 0,27426024 ! positive regulation of immune response GO:0050778 175 100 0,000 0,28120079 0,28131594 ! hormone metabolic process GO:0042445 171 100 0,000 0,28120079 0,28120079