pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6388-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 52 51 7,000 1,686E-10 3,108E-07 GO:0051325|interphase, ! G1/S transition of mitotic cell cycle GO:0000082 21 21 4,000 6,498E-08 5,988E-05 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 3,000 4,89E-07 3,004E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 4,000 9,818E-07 4,523E-04 ! negative regulation of cell differentiation GO:0045596 68 67 5,000 1,246E-06 4,593E-04 ! regulation of cell size GO:0008361 68 68 5,000 1,361E-06 4,181E-04 ! cell cycle checkpoint GO:0000075 42 41 4,000 2,214E-06 5,829E-04 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 5,452E-06 1,256E-03 ! cell cycle arrest GO:0007050 49 49 4,000 5,461E-06 1,118E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 6,236E-06 1,149E-03 GO:0033674|positive regulation of kinase activity, ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 1,528E-05 2,559E-03 ! negative regulation of cell growth GO:0030308 32 32 3,000 2,286E-05 3,511E-03 ! G1/S transition checkpoint GO:0031575 12 11 2,000 2,294E-05 3,252E-03 ! negative regulation of cell size GO:0045792 33 33 3,000 2,592E-05 3,412E-03 ! G1 phase GO:0051318 13 12 2,000 3,047E-05 3,744E-03 ! negative regulation of phosphorylation GO:0042326 13 13 2,000 3,947E-05 4,546E-03 ! negative regulation of growth GO:0045926 37 37 3,000 4,119E-05 4,466E-03 ! DNA damage response, signal transduction GO:0042770 37 37 3,000 4,119E-05 4,218E-03 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 2,000 5,005E-05 4,854E-03 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 2,000 5,005E-05 4,612E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 2,000 7,642E-05 6,707E-03 ! cellular response to nutrient levels GO:0031669 16 16 2,000 7,642E-05 6,402E-03 ! negative regulation of cell development GO:0010721 18 17 2,000 9,246E-05 7,409E-03 GO:0050768|negative regulation of neurogenesis, ! meiosis I GO:0007127 18 18 2,000 1,105E-04 8,488E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 1,105E-04 8,149E-03 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 1,105E-04 7,835E-03 ! gland development GO:0048732 51 49 3,000 1,262E-04 8,614E-03 ! DNA damage checkpoint GO:0000077 19 19 2,000 1,308E-04 8,608E-03 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 1,308E-04 8,311E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 1,366E-04 8,395E-03 ! response to light stimulus GO:0009416 53 52 3,000 1,594E-04 9,477E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 1,768E-04 0,01018453 ! mammary gland development GO:0030879 23 21 2,000 1,782E-04 9,951E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 1,782E-04 9,658E-03 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 2,355E-04 0,0124007 ! regulation of JNK cascade GO:0046328 25 23 2,000 2,355E-04 0,01205623 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 2,000 2,681E-04 0,01335658 ! positive regulation of protein ubiquitination GO:0031398 5 5 1,000 2,786E-04 0,01351158 ! prostate gland development GO:0030850 5 5 1,000 2,786E-04 0,01316513 ! middle ear morphogenesis GO:0042474 5 5 1,000 2,786E-04 0,012836 ! endocrine pancreas development GO:0031018 5 5 1,000 2,786E-04 0,01252293 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 1,000 2,786E-04 0,01222476 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 1,000 2,786E-04 0,01194047 ! regulation of type I interferon production GO:0032479 5 5 1,000 2,786E-04 0,01166909 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 2,786E-04 0,01140978 ! T cell lineage commitment GO:0002360 5 5 1,000 2,786E-04 0,01116174 ! detection of biotic stimulus GO:0009595 5 5 1,000 2,786E-04 0,01092426 ! cellular response to nutrient GO:0031670 5 5 1,000 2,786E-04 0,01069667 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 2,786E-04 0,01047837 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 1,000 2,786E-04 0,0102688 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 2,968E-04 0,01072678 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 3,419E-04 0,01211823 ! activation of caspase activity GO:0006919 27 27 2,000 3,832E-04 0,01332634 ! cell growth GO:0016049 27 27 2,000 3,832E-04 0,01307956 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 1,000 4,165E-04 0,01395545 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of lipid kinase activity GO:0043550 6 6 1,000 4,165E-04 0,01370625 ! RNA methylation GO:0001510 6 6 1,000 4,165E-04 0,01346579 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 4,165E-04 0,01323362 ! regulation of chemokine biosynthetic process GO:0045073 6 6 1,000 4,165E-04 0,01300932 ! oligodendrocyte differentiation GO:0048709 6 6 1,000 4,165E-04 0,0127925 ! L-serine metabolic process GO:0006563 6 6 1,000 4,165E-04 0,01258278 ! ER overload response GO:0006983 6 6 1,000 4,165E-04 0,01237984 ! focal adhesion formation GO:0048041 7 6 1,000 4,165E-04 0,01218333 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,165E-04 0,01199297 GO:0070667|negative regulation of mast cell proliferation, ! rRNA modification GO:0000154 6 6 1,000 4,165E-04 0,01180846 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 4,165E-04 0,01162954 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 4,165E-04 0,01145597 ! response to dsRNA GO:0043331 6 6 1,000 4,165E-04 0,0112875 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,165E-04 0,01112391 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,165E-04 0,010965 ! multicellular organismal aging GO:0010259 6 6 1,000 4,165E-04 0,01081056 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 4,165E-04 0,01066041 ! positive regulation of JNK cascade GO:0046330 7 6 1,000 4,165E-04 0,01051438 ! response to radiation GO:0009314 70 68 3,000 4,51E-04 0,01123118 ! response to UV GO:0009411 29 29 2,000 4,752E-04 0,01167756 ! response to nutrient levels GO:0031667 69 69 3,000 4,769E-04 0,01156414 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 4,769E-04 0,01141396 ! positive regulation of peptidase activity GO:0010952 30 30 2,000 5,261E-04 0,01242993 GO:0043280|positive regulation of caspase activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 5,261E-04 0,01227259 ! skeletal system morphogenesis GO:0048705 31 30 2,000 5,261E-04 0,01211918 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 5,61E-04 0,01276458 ! response to extracellular stimulus GO:0009991 72 72 3,000 5,61E-04 0,01260891 ! B cell activation GO:0042113 31 31 2,000 5,803E-04 0,01288491 ! aging GO:0007568 32 31 2,000 5,803E-04 0,01273152 ! regulation of DNA replication GO:0006275 32 31 2,000 5,803E-04 0,01258174 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 5,803E-04 0,01243544 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 5,811E-04 0,01230953 ! regulation of chemokine production GO:0032642 7 7 1,000 5,811E-04 0,01216965 ! axis specification GO:0009798 7 7 1,000 5,811E-04 0,01203291 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 1,000 5,811E-04 0,01189921 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 1,000 5,811E-04 0,01176845 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 5,811E-04 0,01164053 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 5,811E-04 0,01151536 ! regulation of intracellular pH GO:0051453 7 7 1,000 5,811E-04 0,01139286 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 1,000 5,811E-04 0,01127294 ! response to gamma radiation GO:0010332 8 7 1,000 5,811E-04 0,01115551 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 5,811E-04 0,0110405 ! regulation of osteoclast differentiation GO:0045670 7 7 1,000 5,811E-04 0,01092785 ! regulation of axon extension GO:0030516 7 7 1,000 5,811E-04 0,01081746 ! negative regulation of T cell activation GO:0050868 7 7 1,000 5,811E-04 0,01070929 ! regulation of cellular response to stress GO:0080135 35 33 2,000 6,991E-04 0,01275759 ! activation of protein kinase activity GO:0032147 35 33 2,000 6,991E-04 0,01263252 ! regulation of protein modification process GO:0031399 79 78 3,000 7,601E-04 0,01360147 ! regulation of angiogenesis GO:0045765 35 34 2,000 7,64E-04 0,0135384 ! ear development GO:0043583 34 34 2,000 7,64E-04 0,01340946 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 7,721E-04 0,01342518 ! pancreas development GO:0031016 8 8 1,000 7,721E-04 0,01329971 ! negative regulation of microtubule depolymerization GO:0007026 8 8 1,000 7,721E-04 0,01317656 GO:0031114|regulation of microtubule depolymerization, ! plasma membrane fusion GO:0045026 8 8 1,000 7,721E-04 0,01305568 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 7,721E-04 0,01293699 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 7,721E-04 0,01282044 ! immunoglobulin production during immune response GO:0002381 8 8 1,000 7,721E-04 0,01270597 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 7,721E-04 0,01259353 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 7,721E-04 0,01248306 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 7,721E-04 0,01237451 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 8,325E-04 0,01322678 ! MAPKKK cascade GO:0000165 82 81 3,000 8,765E-04 0,01380637 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 9,048E-04 0,01413228 GO:0045937|positive regulation of phosphate metabolic process, ! meiosis GO:0007126 37 37 2,000 9,81E-04 0,01519372 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 9,81E-04 0,01506711 ! lactation GO:0007595 10 9 1,000 9,894E-04 0,01506996 ! response to osmotic stress GO:0006970 9 9 1,000 9,894E-04 0,01494643 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 9,894E-04 0,01482492 ! regulation of cellular pH GO:0030641 9 9 1,000 9,894E-04 0,01470536 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 1,000 9,894E-04 0,01458772 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 1,000 9,894E-04 0,01447194 ! negative regulation of kinase activity GO:0033673 38 38 2,000 1,061E-03 0,01539987 ! cell-matrix adhesion GO:0007160 39 38 2,000 1,061E-03 0,01527956 ! urogenital system development GO:0001655 38 38 2,000 1,061E-03 0,01516112 ! meiotic cell cycle GO:0051321 38 38 2,000 1,061E-03 0,01504449 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 1,097E-03 0,0154401 ! positive regulation of protein modification process GO:0031401 39 39 2,000 1,145E-03 0,01599202 ! regulation of MAPKKK cascade GO:0043408 41 39 2,000 1,145E-03 0,01587178 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 1,233E-03 0,01695235 ! neuron maturation GO:0042551 10 10 1,000 1,233E-03 0,01682678 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,233E-03 0,01670306 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 1,000 1,233E-03 0,01658114 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,233E-03 0,01646098 ! cAMP metabolic process GO:0046058 10 10 1,000 1,233E-03 0,01634256 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,233E-03 0,01622583 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,233E-03 0,01611075 ! neuromuscular junction development GO:0007528 10 10 1,000 1,233E-03 0,01599729 ! mismatch repair GO:0006298 10 10 1,000 1,233E-03 0,01588542 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,233E-03 0,01577511 ! negative regulation of transferase activity GO:0051348 40 40 2,000 1,234E-03 0,01568059 ! regulation of caspase activity GO:0043281 41 41 2,000 1,326E-03 0,01674066 ! negative regulation of cell cycle GO:0045786 92 91 3,000 1,355E-03 0,01698895 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 1,423E-03 0,01771918 ! cell-substrate adhesion GO:0031589 43 42 2,000 1,423E-03 0,01760025 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 1,501E-03 0,01844683 ! activation of MAPKK activity GO:0000186 12 11 1,000 1,501E-03 0,01832466 ! cellular response to starvation GO:0009267 11 11 1,000 1,501E-03 0,01820411 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 1,501E-03 0,01808512 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 1,501E-03 0,01796769 ! somatic diversification of immunoglobulins GO:0016445 11 11 1,000 1,501E-03 0,01785177 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,501E-03 0,01773733 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 1,629E-03 0,01912819 ! protein import into nucleus GO:0006606 44 44 2,000 1,629E-03 0,01900712 ! regulation of cell growth GO:0001558 97 96 3,000 1,652E-03 0,01915221 ! regulation of DNA binding GO:0051101 47 45 2,000 1,739E-03 0,02003607 ! nuclear import GO:0051170 45 45 2,000 1,739E-03 0,01991162 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 1,739E-03 0,01978871 ! osteoblast differentiation GO:0001649 12 12 1,000 1,796E-03 0,02030182 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 1,796E-03 0,02017803 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 1,796E-03 0,02005574 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,796E-03 0,01993492 ! regulation of peptidase activity GO:0052547 46 46 2,000 1,854E-03 0,0204598 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 1,854E-03 0,02033802 ! positive regulation of ligase activity GO:0051351 47 46 2,000 1,854E-03 0,02021767 ! actin filament organization GO:0007015 50 48 2,000 2,097E-03 0,0227319 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 2,097E-03 0,02259896 ! protein localization in nucleus GO:0034504 48 48 2,000 2,097E-03 0,02246757 ! DNA recombination GO:0006310 48 48 2,000 2,097E-03 0,0223377 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 1,000 2,115E-03 0,02240025 GO:0016444|somatic cell DNA recombination, ! regulation of DNA recombination GO:0000018 13 13 1,000 2,115E-03 0,02227225 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,115E-03 0,0221457 ! negative regulation of DNA replication GO:0008156 13 13 1,000 2,115E-03 0,02202059 ! actin filament bundle formation GO:0051017 13 13 1,000 2,115E-03 0,02189687 ! cell aging GO:0007569 13 13 1,000 2,115E-03 0,02177455 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,115E-03 0,02165358 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,115E-03 0,02153394 ! regulation of axonogenesis GO:0050770 14 13 1,000 2,115E-03 0,02141562 ! immunoglobulin production GO:0002377 13 13 1,000 2,115E-03 0,0212986 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 2,115E-03 0,02118285 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,115E-03 0,02106834 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,115E-03 0,02095507 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 1,000 2,115E-03 0,02084301 ! activation of JUN kinase activity GO:0007257 13 13 1,000 2,115E-03 0,02073215 ! tissue homeostasis GO:0001894 13 13 1,000 2,115E-03 0,02062245 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 1,000 2,115E-03 0,02051391 ! protein tetramerization GO:0051262 13 13 1,000 2,115E-03 0,02040651 ! response to nutrient GO:0007584 49 49 2,000 2,225E-03 0,02136084 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 2,225E-03 0,02125016 ! regulation of ligase activity GO:0051340 50 49 2,000 2,225E-03 0,02114063 ! regulation of neurogenesis GO:0050767 51 50 2,000 2,359E-03 0,02229226 ! regulation of interferon-gamma production GO:0032649 14 14 1,000 2,459E-03 0,02312183 ! regulation of neuron projection development GO:0010975 15 14 1,000 2,459E-03 0,02300446 ! mechanoreceptor differentiation GO:0042490 14 14 1,000 2,459E-03 0,02288828 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 2,459E-03 0,02277326 ! response to retinoic acid GO:0032526 14 14 1,000 2,459E-03 0,02265939 GO:0033189|response to vitamin A, ! base-excision repair GO:0006284 14 14 1,000 2,459E-03 0,02254666 ! rRNA metabolic process GO:0016072 51 51 2,000 2,497E-03 0,02278051 GO:0006364|rRNA processing, ! protein import into nucleus, translocation GO:0000060 15 15 1,000 2,828E-03 0,02567202 ! response to vitamin GO:0033273 15 15 1,000 2,828E-03 0,02554617 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 2,828E-03 0,02542156 ! striated muscle cell differentiation GO:0051146 16 15 1,000 2,828E-03 0,02529815 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 2,828E-03 0,02517594 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 2,828E-03 0,0250549 ! response to starvation GO:0042594 15 15 1,000 2,828E-03 0,02493502 ! response to ionizing radiation GO:0010212 16 15 1,000 2,828E-03 0,02481628 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 2,828E-03 0,02469867 ! somatic diversification of immune receptors GO:0002200 15 15 1,000 2,828E-03 0,02458217 ! negative regulation of cell activation GO:0050866 15 15 1,000 2,828E-03 0,02446676 ! regulation of cell adhesion GO:0030155 56 55 2,000 3,099E-03 0,02669245 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 3,221E-03 0,02760831 ! positive regulation of MAPKKK cascade GO:0043410 17 16 1,000 3,221E-03 0,02748049 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 3,221E-03 0,02735386 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 3,221E-03 0,02722838 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 3,221E-03 0,02710405 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 3,221E-03 0,02698085 ! regulation of nervous system development GO:0051960 57 56 2,000 3,263E-03 0,0272095 ! regulation of binding GO:0051098 60 57 2,000 3,431E-03 0,02848653 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 3,638E-03 0,03006505 ! glucose transport GO:0015758 17 17 1,000 3,638E-03 0,02993083 ! cell junction assembly GO:0034329 18 17 1,000 3,638E-03 0,0297978 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 1,000 3,638E-03 0,02966595 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 3,638E-03 0,02953527 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 3,638E-03 0,02940572 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 3,638E-03 0,02927732 ! myelination GO:0042552 17 17 1,000 3,638E-03 0,02915002 ! regulation of cell development GO:0060284 60 59 2,000 3,784E-03 0,03019312 ! protein localization in organelle GO:0033365 59 59 2,000 3,784E-03 0,03006297 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,079E-03 0,03226225 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,079E-03 0,03212437 ! hexose transport GO:0008645 18 18 1,000 4,079E-03 0,03198767 GO:0015749|monosaccharide transport, ! negative regulation of DNA binding GO:0043392 19 18 1,000 4,079E-03 0,03185213 ! B cell differentiation GO:0030183 18 18 1,000 4,079E-03 0,03171774 ! ensheathment of neurons GO:0007272 18 18 1,000 4,079E-03 0,03158447 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 4,079E-03 0,03145232 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 2,000 4,159E-03 0,0319364 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 4,354E-03 0,03329812 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 2,000 4,354E-03 0,03316052 ! activation of adenylate cyclase activity GO:0007190 19 19 1,000 4,543E-03 0,03445725 ! glial cell differentiation GO:0010001 19 19 1,000 4,543E-03 0,03431604 ! regulation of pH GO:0006885 19 19 1,000 4,543E-03 0,03417597 ! metanephros development GO:0001656 19 19 1,000 4,543E-03 0,03403704 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 1,000 4,543E-03 0,03389924 ! peripheral nervous system development GO:0007422 19 19 1,000 4,543E-03 0,03376255 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 4,543E-03 0,03362696 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 4,555E-03 0,03358042 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 4,762E-03 0,03496254 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 5,031E-03 0,03679392 ! negative regulation of binding GO:0051100 21 20 1,000 5,031E-03 0,03664849 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 5,031E-03 0,03650421 ! cyclic nucleotide metabolic process GO:0009187 20 20 1,000 5,031E-03 0,03636106 ! RNA modification GO:0009451 20 20 1,000 5,031E-03 0,03621902 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 5,191E-03 0,03722803 ! striated muscle tissue development GO:0014706 69 67 2,000 5,415E-03 0,03867937 ! mRNA catabolic process GO:0006402 21 21 1,000 5,542E-03 0,0394344 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 1,000 5,542E-03 0,03928273 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! ear morphogenesis GO:0042471 21 21 1,000 5,542E-03 0,03913223 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 5,542E-03 0,03898287 ! regulation of action potential in neuron GO:0019228 21 21 1,000 5,542E-03 0,03883464 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 5,542E-03 0,03868754 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 5,542E-03 0,03854155 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 5,542E-03 0,03839666 ! negative regulation of protein transport GO:0051224 21 21 1,000 5,542E-03 0,03825285 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 6,075E-03 0,04177978 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 6,075E-03 0,04162446 ! embryonic skeletal system development GO:0048706 22 22 1,000 6,075E-03 0,0414703 ! maintenance of protein location in cell GO:0032507 23 22 1,000 6,075E-03 0,04131727 ! erythrocyte differentiation GO:0030218 23 22 1,000 6,075E-03 0,04116537 ! biopolymer methylation GO:0043414 22 22 1,000 6,075E-03 0,04101458 GO:0032259|methylation, ! detection of external stimulus GO:0009581 23 22 1,000 6,075E-03 0,04086489 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 6,075E-03 0,04071629 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 1,000 6,075E-03 0,04056877 ! cytokine production GO:0001816 22 22 1,000 6,075E-03 0,04042231 ! growth GO:0040007 70 70 2,000 6,119E-03 0,04056795 ! muscle tissue development GO:0060537 72 70 2,000 6,119E-03 0,04042255 ! ribosome biogenesis GO:0042254 71 71 2,000 6,366E-03 0,04190071 ! sensory organ development GO:0007423 72 72 2,000 6,618E-03 0,0434069 ! epithelial cell differentiation GO:0030855 23 23 1,000 6,632E-03 0,04334051 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 6,632E-03 0,04318736 ! endocrine system development GO:0035270 23 23 1,000 6,632E-03 0,0430353 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 6,632E-03 0,04288429 ! mitochondrial transport GO:0006839 24 24 1,000 7,21E-03 0,0464622 ! regulation of action potential GO:0001508 24 24 1,000 7,21E-03 0,04630032 ! gliogenesis GO:0042063 24 24 1,000 7,21E-03 0,04613955 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 7,21E-03 0,0459799 ! T cell differentiation GO:0030217 24 24 1,000 7,21E-03 0,04582135 ! erythrocyte homeostasis GO:0034101 25 24 1,000 7,21E-03 0,04566388 ! maintenance of protein location GO:0045185 25 24 1,000 7,21E-03 0,0455075 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 7,21E-03 0,04535219 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 7,811E-03 0,0489627 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 7,811E-03 0,04879672 ! regulation of T cell proliferation GO:0042129 25 25 1,000 7,811E-03 0,04863187 ! positive regulation of DNA binding GO:0043388 26 25 1,000 7,811E-03 0,04846812 ! negative regulation of immune system process GO:0002683 25 25 1,000 7,811E-03 0,04830548 ! JAK-STAT cascade GO:0007259 26 25 1,000 7,811E-03 0,04814392 ! positive regulation of binding GO:0051099 27 26 1,000 8,433E-03 0,05180702 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 8,433E-03 0,0516349 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 8,433E-03 0,05146393 ! negative regulation of cell migration GO:0030336 26 26 1,000 8,433E-03 0,05129408 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 1,000 8,433E-03 0,05112535 ! regulation of T cell differentiation GO:0045580 26 26 1,000 8,433E-03 0,05095773 ! double-strand break repair GO:0006302 27 26 1,000 8,433E-03 0,0507912 ! response to insulin stimulus GO:0032868 28 26 1,000 8,433E-03 0,05062575 ! maintenance of location in cell GO:0051651 27 26 1,000 8,433E-03 0,05046138 ! synapse organization GO:0050808 26 26 1,000 8,433E-03 0,05029808 ! nuclear transport GO:0051169 79 79 2,000 8,552E-03 0,05084525 GO:0006913|nucleocytoplasmic transport, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 9,077E-03 0,0537909 ! cAMP-mediated signaling GO:0019933 27 27 1,000 9,077E-03 0,0536185 ! inner ear development GO:0048839 27 27 1,000 9,077E-03 0,05344719 ! defense response to bacterium GO:0042742 27 27 1,000 9,077E-03 0,05327698 ! lymphocyte activation GO:0046649 82 81 2,000 9,16E-03 0,05359203 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 9,742E-03 0,05682022 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 1,000 9,742E-03 0,05664098 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 9,742E-03 0,05646286 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 9,742E-03 0,05628586 ! ncRNA processing GO:0034470 83 83 2,000 9,792E-03 0,05639565 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01042883 0,05987641 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01042883 0,05969046 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,01044914 0,05962157 ! RNA catabolic process GO:0006401 30 30 1,000 0,01113617 0,06334554 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 0,01113617 0,06315064 GO:0019724|B cell mediated immunity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,01113617 0,06295692 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01186416 0,06686742 ! membrane fusion GO:0006944 31 31 1,000 0,01186416 0,06666356 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 0,01186416 0,06646093 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01186416 0,06625954 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01186416 0,06605936 ! muscle fiber development GO:0048747 32 32 1,000 0,01261257 0,07001499 ! cell maturation GO:0048469 32 32 1,000 0,01261257 0,06980473 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01261257 0,06959573 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01261257 0,06938799 ! kidney development GO:0001822 32 32 1,000 0,01261257 0,06918147 ! maintenance of location GO:0051235 33 32 1,000 0,01261257 0,06897619 ! tissue morphogenesis GO:0048729 94 93 2,000 0,01333125 0,07269079 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01338118 0,07274785 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01338118 0,07253389 ! regulation of response to stress GO:0080134 97 94 2,000 0,01372035 0,07415426 ! muscle cell differentiation GO:0042692 35 34 1,000 0,01416976 0,07635926 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,01416976 0,07613664 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,01416976 0,07591531 ! detection of stimulus GO:0051606 36 34 1,000 0,01416976 0,07569526 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,01497808 0,07978207 ! mesoderm development GO:0007498 35 35 1,000 0,01497808 0,07955215 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01497808 0,07932356 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,01497808 0,07909627 ! female pregnancy GO:0007565 37 36 1,000 0,01580592 0,08322944 ! muscle organ development GO:0007517 102 100 2,000 0,01619128 0,08501573 ! hemopoiesis GO:0030097 104 100 2,000 0,01619128 0,08477421 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,01665305 0,08694497 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01665305 0,08669936 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,01665305 0,08645514 ! lung development GO:0030324 38 37 1,000 0,01665305 0,08621229 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,01665305 0,0859708 ! adaptive immune response GO:0002250 37 37 1,000 0,01665305 0,08573065 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! axon guidance GO:0007411 39 38 1,000 0,01751927 0,08993874 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01751927 0,08968891 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,01840434 0,093959 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01840434 0,09369944 ! respiratory tube development GO:0030323 40 39 1,000 0,01840434 0,09344132 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,01840434 0,09318461 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01840434 0,09292931 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,01840434 0,09267541 ! respiratory system development GO:0060541 40 39 1,000 0,01840434 0,09242289 ! developmental maturation GO:0021700 39 39 1,000 0,01840434 0,09217174 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01840434 0,09192195 ! protein oligomerization GO:0051259 39 39 1,000 0,01840434 0,09167351 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,01930806 0,09591577 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01930806 0,09565794 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,01930806 0,09540148 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02023021 0,09969056 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,02023021 0,09942472 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,02117057 0,10376958 ! protein ubiquitination GO:0016567 43 42 1,000 0,02117057 0,10349433 ! forebrain development GO:0030900 43 42 1,000 0,02117057 0,10322054 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,02117057 0,10294819 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02117057 0,10267727 ! reproductive structure development GO:0048608 43 43 1,000 0,02212894 0,10704367 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,02212894 0,10676345 ! mitochondrion organization GO:0007005 44 43 1,000 0,02212894 0,10648469 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,02212894 0,10620739 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,02212894 0,10593153 ! mRNA transport GO:0051028 44 44 1,000 0,02310511 0,1103179 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,02310511 0,11003284 ! amine biosynthetic process GO:0009309 46 45 1,000 0,02409886 0,11446958 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02409886 0,11417531 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,02510999 0,11866081 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,02510999 0,11835733 ! regulation of membrane potential GO:0042391 46 46 1,000 0,02510999 0,11805539 ! sex differentiation GO:0007548 47 47 1,000 0,0261383 0,12257732 ! rRNA transcription GO:0009303 5 5 0,000 0,02660952 0,12447042 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02660952 0,12415531 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02660952 0,12384178 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02660952 0,12352984 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02660952 0,12321946 ! reproductive cellular process GO:0048610 5 5 0,000 0,02660952 0,12291064 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02660952 0,12260337 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02660952 0,12229762 ! metencephalon development GO:0022037 5 5 0,000 0,02660952 0,1219934 ! water transport GO:0006833 5 5 0,000 0,02660952 0,12169069 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02660952 0,12138947 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02660952 0,12108974 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02660952 0,12079149 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02660952 0,12049471 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02660952 0,12019938 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02660952 0,11990549 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02660952 0,11961304 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02660952 0,11932201 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02660952 0,11903239 ! filopodium assembly GO:0046847 7 5 0,000 0,02660952 0,11874418 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02660952 0,11845736 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02660952 0,11817192 ! GTP metabolic process GO:0046039 5 5 0,000 0,02660952 0,11788785 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02660952 0,11760515 ! mRNA stabilization GO:0048255 5 5 0,000 0,02660952 0,11732379 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02660952 0,11704379 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02660952 0,11676511 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02660952 0,11648776 ! social behavior GO:0035176 5 5 0,000 0,02660952 0,11621172 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02660952 0,11593699 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02660952 0,11566355 ! memory GO:0007613 5 5 0,000 0,02660952 0,1153914 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02660952 0,11512053 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02660952 0,11485093 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02660952 0,11458258 ! response to lipid GO:0033993 5 5 0,000 0,02660952 0,11431549 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02660952 0,11404964 ! hippocampus development GO:0021766 6 5 0,000 0,02660952 0,11378503 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02660952 0,11352163 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02660952 0,11325946 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02660952 0,11299849 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02660952 0,11273873 ! heart looping GO:0001947 5 5 0,000 0,02660952 0,11248015 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02660952 0,11222276 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02660952 0,11196654 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02660952 0,11171149 ! pH reduction GO:0045851 5 5 0,000 0,02660952 0,11145761 GO:0051452|intracellular pH reduction, ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02660952 0,11120487 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02660952 0,11095327 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02660952 0,11070281 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02660952 0,11045348 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02660952 0,11020527 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02660952 0,10995818 ! adrenal gland development GO:0030325 5 5 0,000 0,02660952 0,10971218 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02660952 0,10946729 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02660952 0,10922349 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02660952 0,10898077 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02660952 0,10873913 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02660952 0,10849855 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02660952 0,10825904 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02660952 0,10802059 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02660952 0,10778318 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02660952 0,10754681 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02660952 0,10731148 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02660952 0,10707718 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02660952 0,10684389 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02660952 0,10661162 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02660952 0,10638036 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02660952 0,1061501 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02660952 0,10592083 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02660952 0,10569256 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02660952 0,10546526 ! response to ATP GO:0033198 5 5 0,000 0,02660952 0,10523894 ! regulation of appetite GO:0032098 5 5 0,000 0,02660952 0,10501359 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02660952 0,1047892 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02660952 0,10456577 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,02660952 0,10434329 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02660952 0,10412175 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02660952 0,10390116 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02660952 0,10368149 ! receptor clustering GO:0043113 5 5 0,000 0,02660952 0,10346276 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02660952 0,10324494 ! fear response GO:0042596 5 5 0,000 0,02660952 0,10302804 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02660952 0,10281205 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02660952 0,10259696 ! retinol metabolic process GO:0042572 5 5 0,000 0,02660952 0,10238277 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02660952 0,10216947 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02660952 0,10195706 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02660952 0,10174553 ! parturition GO:0007567 5 5 0,000 0,02660952 0,10153488 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02660952 0,1013251 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02660952 0,10111618 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02660952 0,10090812 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02660952 0,10070092 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02660952 0,10049456 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02660952 0,10028905 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02660952 0,10008438 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02660952 0,09988054 ! response to UV-B GO:0010224 5 5 0,000 0,02660952 0,09967753 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02660952 0,09947535 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02660952 0,09927398 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02660952 0,09907343 ! interaction with symbiont GO:0051702 5 5 0,000 0,02660952 0,09887368 ! cellular extravasation GO:0045123 5 5 0,000 0,02660952 0,09867474 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02660952 0,0984766 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02660952 0,09827925 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02660952 0,09808269 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02660952 0,09788692 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02660952 0,09769192 ! response to amine stimulus GO:0014075 5 5 0,000 0,02660952 0,09749771 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02660952 0,09730426 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02660952 0,09711158 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02660952 0,09691966 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02660952 0,09672849 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02660952 0,09653808 ! neuron recognition GO:0008038 5 5 0,000 0,02660952 0,09634842 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02660952 0,0961595 ! decidualization GO:0046697 5 5 0,000 0,02660952 0,09597132 ! hair follicle maturation GO:0048820 5 5 0,000 0,02660952 0,09578388 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02660952 0,09559717 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02660952 0,09541118 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02660952 0,09522592 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02660952 0,09504137 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02660952 0,09485754 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02660952 0,09467441 ! postreplication repair GO:0006301 5 5 0,000 0,02660952 0,094492 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02660952 0,09431028 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02660952 0,09412926 ! histone methylation GO:0016571 5 5 0,000 0,02660952 0,09394894 ! DNA methylation GO:0006306 5 5 0,000 0,02660952 0,0937693 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02660952 0,09359036 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02660952 0,09341209 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02660952 0,0932345 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02660952 0,09305758 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02660952 0,09288134 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02660952 0,09270576 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02660952 0,09253084 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02660952 0,09235658 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02660952 0,09218298 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02660952 0,09201003 ! sterol catabolic process GO:0016127 5 5 0,000 0,02660952 0,09183773 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02660952 0,09166607 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02660952 0,09149505 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02660952 0,09132467 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02660952 0,09115492 ! zymogen activation GO:0031638 5 5 0,000 0,02660952 0,0909858 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02660952 0,09081731 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02660952 0,09064944 GO:0002820|negative regulation of adaptive immune response, ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02660952 0,09048219 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02660952 0,09031555 ! nucleosome positioning GO:0016584 5 5 0,000 0,02660952 0,09014953 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02660952 0,08998412 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02660952 0,08981932 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02660952 0,08965511 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02660952 0,08949151 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02660952 0,0893285 ! NADPH regeneration GO:0006740 5 5 0,000 0,02660952 0,08916608 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02660952 0,08900426 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02660952 0,08884302 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02660952 0,08868236 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02660952 0,08852229 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02660952 0,08836279 ! sarcomere organization GO:0045214 5 5 0,000 0,02660952 0,08820386 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02660952 0,08804551 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02660952 0,08788772 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02660952 0,08773049 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02660952 0,08757383 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02660952 0,08741773 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02660952 0,08726218 ! spleen development GO:0048536 5 5 0,000 0,02660952 0,08710719 ! male genitalia development GO:0030539 5 5 0,000 0,02660952 0,08695274 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02660952 0,08679884 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02660952 0,08664549 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02660952 0,08649267 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02660952 0,0863404 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02660952 0,08618866 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02660952 0,08603745 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02660952 0,08588677 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02660952 0,08573662 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02660952 0,08558699 ! ATP catabolic process GO:0006200 5 5 0,000 0,02660952 0,08543789 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02660952 0,0852893 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02660952 0,08514123 ! blastocyst formation GO:0001825 5 5 0,000 0,02660952 0,08499367 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02660952 0,08484662 ! embryonic gut development GO:0048566 5 5 0,000 0,02660952 0,08470008 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02660952 0,08455405 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02660952 0,08440851 ! activation of innate immune response GO:0002218 5 5 0,000 0,02660952 0,08426348 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02660952 0,08411895 ! catecholamine transport GO:0051937 5 5 0,000 0,02660952 0,08397491 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02660952 0,08383136 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02660952 0,0836883 ! muscle adaptation GO:0043500 5 5 0,000 0,02660952 0,08354573 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02660952 0,08340365 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02660952 0,08326205 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02660952 0,08312093 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02660952 0,08298028 ! defense response to fungus GO:0050832 5 5 0,000 0,02660952 0,08284011 ! lysogeny GO:0030069 5 5 0,000 0,02660952 0,08270042 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02660952 0,08256119 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02660952 0,08242243 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02660952 0,08228414 ! response to nicotine GO:0035094 5 5 0,000 0,02660952 0,08214631 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02660952 0,08200894 ! mitochondrion localization GO:0051646 5 5 0,000 0,02660952 0,08187203 ! nucleus localization GO:0051647 5 5 0,000 0,02660952 0,08173558 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02660952 0,08159958 ! calcium ion transport GO:0006816 48 48 1,000 0,02718358 0,0832215 ! leukocyte differentiation GO:0002521 50 49 1,000 0,02824564 0,08632953 ! ossification GO:0001503 50 49 1,000 0,02824564 0,0861866 GO:0060348|bone development, ! divalent metal ion transport GO:0070838 49 49 1,000 0,02824564 0,08604414 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,02824564 0,08590216 GO:0060538|skeletal muscle organ development, ! response to bacterium GO:0009617 50 49 1,000 0,02824564 0,08576064 ! negative regulation of transport GO:0051051 51 50 1,000 0,02932426 0,08888917 ! RNA transport GO:0050658 50 50 1,000 0,02932426 0,08874321 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 1,000 0,02932426 0,08859773 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,02932426 0,08845272 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,02932426 0,08830819 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,03041926 0,09145627 ! RNA localization GO:0006403 52 52 1,000 0,03153043 0,09464264 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,03153043 0,09448875 ! cell fate commitment GO:0045165 52 52 1,000 0,03153043 0,09433536 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03184813 0,09513145 ! axon extension GO:0048675 7 6 0,000 0,03184813 0,09497752 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03184813 0,09482408 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,03184813 0,09467114 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,03184813 0,09451869 ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03184813 0,09436673 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03184813 0,09421526 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03184813 0,09406427 ! virus-host interaction GO:0019048 6 6 0,000 0,03184813 0,09391377 ! regulation of S phase GO:0033261 6 6 0,000 0,03184813 0,09376375 ! myotube differentiation GO:0014902 6 6 0,000 0,03184813 0,0936142 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03184813 0,09346514 ! bone remodeling GO:0046849 6 6 0,000 0,03184813 0,09331654 ! N-glycan processing GO:0006491 6 6 0,000 0,03184813 0,09316842 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03184813 0,09302077 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03184813 0,09287358 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03184813 0,09272687 ! cartilage condensation GO:0001502 7 6 0,000 0,03184813 0,09258061 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03184813 0,09243481 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03184813 0,09228947 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03184813 0,09214459 ! artery development GO:0060840 6 6 0,000 0,03184813 0,09200017 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03184813 0,09185619 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03184813 0,09171266 ! androgen metabolic process GO:0008209 6 6 0,000 0,03184813 0,09156959 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03184813 0,09142696 ! limbic system development GO:0021761 7 6 0,000 0,03184813 0,09128477 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03184813 0,09114302 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03184813 0,09100171 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03184813 0,09086084 ! pathogenesis GO:0009405 6 6 0,000 0,03184813 0,09072041 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03184813 0,09058041 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03184813 0,09044084 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03184813 0,0903017 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03184813 0,09016299 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03184813 0,0900247 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03184813 0,08988684 ! arginine metabolic process GO:0006525 6 6 0,000 0,03184813 0,0897494 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03184813 0,08961237 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03184813 0,08947577 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03184813 0,08933958 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03184813 0,08920381 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03184813 0,08906845 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,03184813 0,08893349 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03184813 0,08879895 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03184813 0,08866481 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03184813 0,08853108 ! regulation of heart rate GO:0002027 6 6 0,000 0,03184813 0,08839775 ! lipid digestion GO:0044241 6 6 0,000 0,03184813 0,08826482 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03184813 0,08813229 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03184813 0,08800016 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03184813 0,08786842 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03184813 0,08773708 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03184813 0,08760613 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03184813 0,08747557 ! ruffle organization GO:0031529 6 6 0,000 0,03184813 0,0873454 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03184813 0,08721561 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03184813 0,08708621 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03184813 0,08695719 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03184813 0,08682856 ! L-amino acid transport GO:0015807 6 6 0,000 0,03184813 0,0867003 ! bone mineralization GO:0030282 6 6 0,000 0,03184813 0,08657243 GO:0031214|biomineral formation, ! negative regulation of ossification GO:0030279 6 6 0,000 0,03184813 0,08644493 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03184813 0,0863178 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03184813 0,08619105 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03184813 0,08606467 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03184813 0,08593866 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03184813 0,08581302 ! regulation of organ growth GO:0046620 6 6 0,000 0,03184813 0,08568775 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03184813 0,08556284 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03184813 0,08543829 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03184813 0,08531411 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03184813 0,08519028 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03184813 0,08506682 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03184813 0,08494371 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03184813 0,08482096 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03184813 0,08469857 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03184813 0,08457652 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03184813 0,08445483 ! erythrocyte development GO:0048821 6 6 0,000 0,03184813 0,08433349 ! renal water homeostasis GO:0003091 6 6 0,000 0,03184813 0,08421249 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03184813 0,08409184 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03184813 0,08397154 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03184813 0,08385158 ! ribosome assembly GO:0042255 6 6 0,000 0,03184813 0,08373196 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03184813 0,08361269 ! diencephalon development GO:0021536 6 6 0,000 0,03184813 0,08349375 ! fucose catabolic process GO:0019317 6 6 0,000 0,03184813 0,08337515 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03184813 0,08325689 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03184813 0,08313896 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03184813 0,08302137 ! regulation of cell division GO:0051302 6 6 0,000 0,03184813 0,0829041 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03184813 0,08278717 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03184813 0,08267057 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03184813 0,0825543 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03184813 0,08243835 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03184813 0,08232273 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03184813 0,08220743 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03184813 0,08209246 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03184813 0,0819778 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03184813 0,08186347 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03184813 0,08174945 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03184813 0,08163575 ! thymus development GO:0048538 6 6 0,000 0,03184813 0,08152237 ! lymph node development GO:0048535 6 6 0,000 0,03184813 0,0814093 ! organic cation transport GO:0015695 6 6 0,000 0,03184813 0,08129655 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03184813 0,0811841 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03184813 0,08107197 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03184813 0,08096015 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! sperm-egg recognition GO:0035036 7 6 0,000 0,03184813 0,08084863 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03184813 0,08073742 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03184813 0,08062652 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03184813 0,08051592 ! alditol metabolic process GO:0019400 6 6 0,000 0,03184813 0,08040562 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03184813 0,08029563 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03184813 0,08018594 ! maternal placenta development GO:0001893 6 6 0,000 0,03184813 0,08007654 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03184813 0,07996745 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03184813 0,07985865 ! localization within membrane GO:0051668 6 6 0,000 0,03184813 0,07975014 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,03265758 0,08166611 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03265758 0,08155546 ! regulation of protein transport GO:0051223 53 53 1,000 0,03265758 0,0814451 GO:0070201|regulation of establishment of protein localization, ! response to virus GO:0009615 54 54 1,000 0,03380052 0,08418157 ! in utero embryonic development GO:0001701 55 55 1,000 0,03495906 0,08694945 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,03495906 0,08683226 ! reproductive developmental process GO:0003006 56 56 1,000 0,03613299 0,08962733 ! extracellular structure organization GO:0043062 56 56 1,000 0,03613299 0,08950686 ! respiratory burst GO:0045730 7 7 0,000 0,03705931 0,09167826 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03705931 0,09155536 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03705931 0,0914328 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03705931 0,09131056 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,03705931 0,09118865 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03705931 0,09106707 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03705931 0,09094581 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03705931 0,09082487 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03705931 0,09070425 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03705931 0,09058395 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03705931 0,09046398 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03705931 0,09034431 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03705931 0,09022497 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03705931 0,09010594 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03705931 0,08998722 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03705931 0,08986882 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03705931 0,08975072 ! visual behavior GO:0007632 7 7 0,000 0,03705931 0,08963294 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03705931 0,08951547 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03705931 0,0893983 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03705931 0,08928144 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03705931 0,08916488 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03705931 0,08904863 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03705931 0,08893268 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03705931 0,08881704 ! digestive system development GO:0055123 7 7 0,000 0,03705931 0,08870169 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03705931 0,08858664 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03705931 0,08847189 ! protein targeting to ER GO:0045047 8 7 0,000 0,03705931 0,08835744 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03705931 0,08824328 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03705931 0,08812942 ! endoderm development GO:0007492 7 7 0,000 0,03705931 0,08801585 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03705931 0,08790258 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03705931 0,08778959 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03705931 0,0876769 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03705931 0,08756449 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03705931 0,08745237 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03705931 0,08734054 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03705931 0,08722899 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03705931 0,08711773 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03705931 0,08700675 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03705931 0,08689606 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03705931 0,08678564 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03705931 0,08667551 ! UV protection GO:0009650 7 7 0,000 0,03705931 0,08656565 ! DNA integration GO:0015074 7 7 0,000 0,03705931 0,08645608 ! myofibril assembly GO:0030239 7 7 0,000 0,03705931 0,08634678 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,03705931 0,08623775 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03705931 0,08612901 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03705931 0,08602053 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03705931 0,08591233 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03705931 0,0858044 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03705931 0,08569674 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03705931 0,08558935 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03705931 0,08548223 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03705931 0,08537538 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03705931 0,08526879 ! axon cargo transport GO:0008088 7 7 0,000 0,03705931 0,08516247 ! eating behavior GO:0042755 7 7 0,000 0,03705931 0,08505642 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03705931 0,08495062 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03705931 0,0848451 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03705931 0,08473983 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03705931 0,08463482 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03705931 0,08453008 ! cranial nerve development GO:0021545 7 7 0,000 0,03705931 0,08442559 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03705931 0,08432136 ! induction of an organ GO:0001759 7 7 0,000 0,03705931 0,08421739 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03705931 0,08411367 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03705931 0,08401021 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03705931 0,083907 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03705931 0,08380405 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03705931 0,08370135 ! platelet activation GO:0030168 8 7 0,000 0,03705931 0,0835989 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03705931 0,0834967 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03705931 0,08339475 ! natural killer cell activation GO:0030101 7 7 0,000 0,03705931 0,08329305 ! NADP metabolic process GO:0006739 7 7 0,000 0,03705931 0,0831916 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03705931 0,08309039 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03705931 0,08298943 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03705931 0,08288872 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03705931 0,08278824 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03705931 0,08268802 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03705931 0,08258803 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03705931 0,08248829 ! cell-cell recognition GO:0009988 8 7 0,000 0,03705931 0,08238878 ! hormone catabolic process GO:0042447 7 7 0,000 0,03705931 0,08228952 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03705931 0,0821905 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03705931 0,08209171 ! oxygen transport GO:0015671 7 7 0,000 0,03705931 0,08199316 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03705931 0,08189485 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03705931 0,08179677 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03705931 0,08169893 ! cell killing GO:0001906 7 7 0,000 0,03705931 0,08160132 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03705931 0,08150394 ! adult feeding behavior GO:0008343 7 7 0,000 0,03705931 0,0814068 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03705931 0,08130988 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03705931 0,0812132 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03705931 0,08111675 ! response to cold GO:0009409 7 7 0,000 0,03705931 0,08102052 ! regulation of protein localization GO:0032880 58 57 1,000 0,03732214 0,08149847 ! innate immune response GO:0045087 58 58 1,000 0,03852632 0,08402841 ! immune effector process GO:0002252 59 59 1,000 0,03974533 0,08658469 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,040979 0,08916683 ! protein polymerization GO:0051258 65 60 1,000 0,040979 0,08906168 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,04222714 0,09166623 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04224319 0,09159317 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04224319 0,09148554 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04224319 0,09137816 ! positive regulation of translation GO:0045727 8 8 0,000 0,04224319 0,09127103 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04224319 0,09116416 ! superoxide anion generation GO:0042554 8 8 0,000 0,04224319 0,09105753 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04224319 0,09095116 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04224319 0,09084503 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04224319 0,09073915 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04224319 0,09063352 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04224319 0,09052813 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04224319 0,09042299 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,04224319 0,09031809 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04224319 0,09021343 ! zinc ion transport GO:0006829 8 8 0,000 0,04224319 0,09010902 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04224319 0,09000485 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04224319 0,08990091 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04224319 0,08979722 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04224319 0,08969377 ! lipid localization GO:0010876 8 8 0,000 0,04224319 0,08959055 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04224319 0,08948758 ! response to cAMP GO:0051591 8 8 0,000 0,04224319 0,08938484 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04224319 0,08928233 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04224319 0,08918006 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04224319 0,08907802 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04224319 0,08897622 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04224319 0,08887465 ! sensory perception of taste GO:0050909 8 8 0,000 0,04224319 0,08877331 ! organelle fusion GO:0048284 8 8 0,000 0,04224319 0,0886722 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04224319 0,08857132 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04224319 0,08847067 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04224319 0,08837025 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04224319 0,08827006 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04224319 0,08817009 ! sperm motility GO:0030317 8 8 0,000 0,04224319 0,08807035 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04224319 0,08797084 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04224319 0,08787155 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04224319 0,08777248 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04224319 0,08767364 ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04224319 0,08757502 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04224319 0,08747662 ! Golgi organization GO:0007030 8 8 0,000 0,04224319 0,08737844 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04224319 0,08728048 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04224319 0,08718275 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,04224319 0,08708523 ! fructose metabolic process GO:0006000 8 8 0,000 0,04224319 0,08698792 ! mannose metabolic process GO:0006013 9 8 0,000 0,04224319 0,08689084 ! NAD metabolic process GO:0019674 8 8 0,000 0,04224319 0,08679397 ! sex determination GO:0007530 8 8 0,000 0,04224319 0,08669732 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04224319 0,08660088 ! response to fungus GO:0009620 8 8 0,000 0,04224319 0,08650466 ! stem cell differentiation GO:0048863 8 8 0,000 0,04224319 0,08640865 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04224319 0,08631285 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04224319 0,08621727 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04224319 0,08612189 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04224319 0,08602673 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04224319 0,08593178 ! vasoconstriction GO:0042310 8 8 0,000 0,04224319 0,08583704 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04224319 0,0857425 ! muscle cell development GO:0055001 8 8 0,000 0,04224319 0,08564818 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04224319 0,08555406 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04224319 0,08546015 ! sensory perception of pain GO:0019233 8 8 0,000 0,04224319 0,08536644 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04224319 0,08527294 ! mRNA cleavage GO:0006379 8 8 0,000 0,04224319 0,08517964 ! chromatin silencing GO:0006342 8 8 0,000 0,04224319 0,08508655 ! tissue regeneration GO:0042246 8 8 0,000 0,04224319 0,08499366 ! salivary gland development GO:0007431 8 8 0,000 0,04224319 0,08490097 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04224319 0,08480849 ! T cell homeostasis GO:0043029 8 8 0,000 0,04224319 0,0847162 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04224319 0,08462412 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,04224319 0,08453224 ! water homeostasis GO:0030104 8 8 0,000 0,04224319 0,08444056 ! cofactor transport GO:0051181 8 8 0,000 0,04224319 0,08434907 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04224319 0,08425778 ! acid secretion GO:0046717 8 8 0,000 0,04224319 0,08416669 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,04224319 0,0840758 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04224319 0,0839851 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04224319 0,0838946 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04224319 0,0838043 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04224319 0,08371419 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04224319 0,08362427 ! regulation of RNA stability GO:0043487 8 8 0,000 0,04224319 0,08353454 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04224319 0,08344501 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04224319 0,08335567 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04224319 0,08326652 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04224319 0,08317756 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04224319 0,08308879 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04224319 0,0830002 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04224319 0,08291181 ! developmental induction GO:0031128 8 8 0,000 0,04224319 0,08282361 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04224319 0,08273559 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04224319 0,08264776 ! actin filament polymerization GO:0030041 9 8 0,000 0,04224319 0,08256012 ! peptide hormone processing GO:0016486 8 8 0,000 0,04224319 0,08247266 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04224319 0,08238539 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04224319 0,0822983 ! axonogenesis GO:0007409 66 62 1,000 0,04348957 0,08463705 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,04348957 0,08454777 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,04348957 0,08445868 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,04605658 0,08934977 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04739991 0,09185913 ! positive regulation of cell size GO:0045793 9 9 0,000 0,04739991 0,09176264 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,04739991 0,09166635 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04739991 0,09157027 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04739991 0,09147438 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,04739991 0,0913787 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,04739991 0,09128321 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,04739991 0,09118793 ! viral genome replication GO:0019079 9 9 0,000 0,04739991 0,09109284 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04739991 0,09099795 ! copper ion transport GO:0006825 9 9 0,000 0,04739991 0,09090326 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04739991 0,09080877 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04739991 0,09071447 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04739991 0,09062037 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04739991 0,09052646 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04739991 0,09043275 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04739991 0,09033923 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04739991 0,0902459 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,04739991 0,09015277 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,04739991 0,09005983 ! phospholipid efflux GO:0033700 9 9 0,000 0,04739991 0,08996708 ! response to alkaloid GO:0043279 10 9 0,000 0,04739991 0,08987452 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,04739991 0,08978215 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04739991 0,08968997 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,04739991 0,08959798 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04739991 0,08950618 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04739991 0,08941457 ! response to ethanol GO:0045471 9 9 0,000 0,04739991 0,08932314 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,04739991 0,0892319 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,04739991 0,08914085 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,04739991 0,08904998 ! methionine metabolic process GO:0006555 9 9 0,000 0,04739991 0,0889593 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04739991 0,0888688 ! cerebral cortex development GO:0021987 9 9 0,000 0,04739991 0,08877849 ! pigmentation during development GO:0048066 9 9 0,000 0,04739991 0,08868836 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04739991 0,08859841 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04739991 0,08850865 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,04739991 0,08841906 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,04739991 0,08832966 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04739991 0,08824044 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04739991 0,0881514 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,04739991 0,08806253 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,04739991 0,08797385 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,04739991 0,08788535 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04739991 0,08779702 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,04739991 0,08770887 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04739991 0,0876209 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04739991 0,0875331 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04739991 0,08744548 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04739991 0,08735803 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,04739991 0,08727076 ! DNA replication initiation GO:0006270 9 9 0,000 0,04739991 0,08718367 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,04739991 0,08709674 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,04739991 0,08700999 ! histone acetylation GO:0016573 9 9 0,000 0,04739991 0,08692342 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04739991 0,08683701 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04739991 0,08675078 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04739991 0,08666472 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,04739991 0,08657882 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04739991 0,0864931 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04739991 0,08640755 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,04739991 0,08632217 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04739991 0,08623695 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,04739991 0,08615191 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04739991 0,08606703 ! collagen catabolic process GO:0030574 9 9 0,000 0,04739991 0,08598232 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04739991 0,08589777 ! purine base metabolic process GO:0006144 9 9 0,000 0,04739991 0,08581339 ! gas transport GO:0015669 9 9 0,000 0,04739991 0,08572918 ! cholesterol efflux GO:0033344 9 9 0,000 0,04739991 0,08564513 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04739991 0,08556125 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04739991 0,08547753 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04739991 0,08539397 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,04739991 0,08531058 ! defense response to virus GO:0051607 9 9 0,000 0,04739991 0,08522735 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04739991 0,08514428 ! actin filament-based movement GO:0030048 9 9 0,000 0,04739991 0,08506138 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,0486786 0,08727107 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,0500098 0,08957051 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05252961 0,09399231 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,05252961 0,09390114 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05252961 0,09381015 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,05252961 0,09371934 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05252961 0,0936287 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05252961 0,09353824 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05252961 0,09344795 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05252961 0,09335784 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05252961 0,0932679 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05252961 0,09317813 ! hormone secretion GO:0046879 10 10 0,000 0,05252961 0,09308854 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05252961 0,09299912 GO:0006044|N-acetylglucosamine metabolic process, ! inositol metabolic process GO:0006020 10 10 0,000 0,05252961 0,09290987 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05252961 0,09282079 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05252961 0,09273188 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05252961 0,09264314 ! glial cell development GO:0021782 10 10 0,000 0,05252961 0,09255457 ! phototransduction GO:0007602 11 10 0,000 0,05252961 0,09246617 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,05252961 0,09237794 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05252961 0,09228988 ! fat cell differentiation GO:0045444 10 10 0,000 0,05252961 0,09220198 ! myoblast differentiation GO:0045445 10 10 0,000 0,05252961 0,09211425 ! centrosome cycle GO:0007098 10 10 0,000 0,05252961 0,09202669 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05252961 0,0919393 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05252961 0,09185207 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05252961 0,091765 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05252961 0,09167811 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,05252961 0,09159137 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,05252961 0,0915048 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05252961 0,09141839 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05252961 0,09133215 ! plasma membrane organization GO:0007009 10 10 0,000 0,05252961 0,09124607 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05252961 0,09116015 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,05252961 0,09107439 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,05252961 0,0909888 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,05252961 0,09090336 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05252961 0,09081809 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05252961 0,09073297 ! exocrine system development GO:0035272 10 10 0,000 0,05252961 0,09064801 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,05252961 0,09056322 ! embryo implantation GO:0007566 11 10 0,000 0,05252961 0,09047858 ! regulation of protein binding GO:0043393 11 10 0,000 0,05252961 0,0903941 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05252961 0,09030978 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05252961 0,09022561 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05252961 0,0901416 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05252961 0,09005775 ! protein export from nucleus GO:0006611 10 10 0,000 0,05252961 0,08997405 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05252961 0,08989051 ! cytolysis GO:0019835 10 10 0,000 0,05252961 0,08980712 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05252961 0,08972389 GO:0030501|positive regulation of bone mineralization, ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,05252961 0,08964081 ! histone deacetylation GO:0016575 10 10 0,000 0,05252961 0,08955789 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05252961 0,08947512 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05252961 0,0893925 ! gland morphogenesis GO:0022612 10 10 0,000 0,05252961 0,08931004 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05252961 0,08922772 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05252961 0,08914556 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05252961 0,08906355 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05252961 0,08898169 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,05252961 0,08889998 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05252961 0,08881842 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05252961 0,08873701 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05252961 0,08865575 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05252961 0,08857464 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,05252961 0,08849367 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,05252961 0,08841286 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,05252961 0,08833219 ! nerve development GO:0021675 10 10 0,000 0,05252961 0,08825167 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,05252961 0,08817129 ! gut development GO:0048565 10 10 0,000 0,05252961 0,08809106 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,05252961 0,08801098 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,05252961 0,08793104 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05252961 0,08785125 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05252961 0,0877716 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,05252961 0,0876921 ! protein stabilization GO:0050821 10 10 0,000 0,05252961 0,08761274 ! sensory perception of sound GO:0007605 71 69 1,000 0,0527117 0,08783695 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,0527117 0,0877576 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,0527117 0,0876784 ! cell part morphogenesis GO:0032990 75 70 1,000 0,05408207 0,08987669 ! wound healing GO:0042060 74 70 1,000 0,05408207 0,08979572 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,05408207 0,08971489 GO:0016053|organic acid biosynthetic process, ! regulation of cell migration GO:0030334 71 71 1,000 0,05546515 0,09192649 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,05546515 0,0918439 ! regulation of cell activation GO:0050865 71 71 1,000 0,05546515 0,09176146 ! regulation of cytokine production GO:0001817 72 72 1,000 0,05686077 0,09398601 ! protein secretion GO:0009306 11 11 0,000 0,05763244 0,09517615 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,05763244 0,09509094 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,05763244 0,09500589 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,05763244 0,09492099 ! negative regulation of defense response GO:0031348 11 11 0,000 0,05763244 0,09483624 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,05763244 0,09475164 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,05763244 0,09466719 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,05763244 0,09458289 ! skin development GO:0043588 11 11 0,000 0,05763244 0,09449874 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,05763244 0,09441474 ! signal complex assembly GO:0007172 11 11 0,000 0,05763244 0,09433089 ! microtubule-based transport GO:0010970 11 11 0,000 0,05763244 0,09424719 ! endothelial cell migration GO:0043542 11 11 0,000 0,05763244 0,09416364 ! peroxisomal transport GO:0043574 11 11 0,000 0,05763244 0,09408023 ! protein amino acid methylation GO:0006479 11 11 0,000 0,05763244 0,09399698 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,05763244 0,09391387 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,05763244 0,09383091 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,05763244 0,09374809 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,05763244 0,09366542 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,05763244 0,09358289 ! T cell proliferation GO:0042098 11 11 0,000 0,05763244 0,09350051 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,05763244 0,09341828 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,05763244 0,09333619 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,05763244 0,09325424 ! spinal cord development GO:0021510 11 11 0,000 0,05763244 0,09317244 ! smooth muscle contraction GO:0006939 11 11 0,000 0,05763244 0,09309078 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,05763244 0,09300927 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,05763244 0,0929279 ! digestive system process GO:0022600 11 11 0,000 0,05763244 0,09284667 ! mitotic spindle organization GO:0007052 11 11 0,000 0,05763244 0,09276558 ! fucose metabolic process GO:0006004 11 11 0,000 0,05763244 0,09268463 ! membrane budding GO:0006900 11 11 0,000 0,05763244 0,09260382 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,05763244 0,09252316 ! monoamine transport GO:0015844 11 11 0,000 0,05763244 0,09244263 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,05763244 0,09236225 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,05763244 0,092282 ! body fluid secretion GO:0007589 11 11 0,000 0,05763244 0,0922019 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,05763244 0,09212193 ! intermediate filament-based process GO:0045103 11 11 0,000 0,05763244 0,0920421 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,05763244 0,09196241 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,05763244 0,09188286 ! membrane depolarization GO:0051899 11 11 0,000 0,05763244 0,09180344 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,05763244 0,09172417 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,05763244 0,09164503 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,05763244 0,09156602 ! oogenesis GO:0048477 11 11 0,000 0,05763244 0,09148715 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,05763244 0,09140842 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,05763244 0,09132982 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,05763244 0,09125136 ! muscle maintenance GO:0046716 12 11 0,000 0,05763244 0,09117303 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,05763244 0,09109484 ! hindbrain development GO:0030902 11 11 0,000 0,05763244 0,09101678 ! steroid catabolic process GO:0006706 11 11 0,000 0,05763244 0,09093886 ! endocrine process GO:0050886 11 11 0,000 0,05763244 0,09086107 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,05763244 0,09078341 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,05763244 0,09070588 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,05763244 0,09062849 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,06256544 0,09830188 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,06270852 0,09844276 ! translational initiation GO:0006413 12 12 0,000 0,06270852 0,09835898 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06270852 0,09827534 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06270852 0,09819185 ! initiation of viral infection GO:0019059 12 12 0,000 0,06270852 0,09810849 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06270852 0,09802528 ! iron ion transport GO:0006826 13 12 0,000 0,06270852 0,09794221 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06270852 0,09785927 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06270852 0,09777648 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06270852 0,09769383 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06270852 0,09761132 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06270852 0,09752895 ! collagen metabolic process GO:0032963 12 12 0,000 0,06270852 0,09744671 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06270852 0,09736462 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06270852 0,09728266 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06270852 0,09720084 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06270852 0,09711916 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06270852 0,09703762 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06270852 0,09695621 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06270852 0,09687494 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06270852 0,0967938 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06270852 0,09671281 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06270852 0,09663194 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06270852 0,09655121 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06270852 0,09647062 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06270852 0,09639016 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06270852 0,09630984 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06270852 0,09622964 ! acute-phase response GO:0006953 12 12 0,000 0,06270852 0,09614959 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06270852 0,09606966 ! vacuolar transport GO:0007034 12 12 0,000 0,06270852 0,09598987 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06270852 0,09591021 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06270852 0,09583068 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06270852 0,09575129 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06270852 0,09567202 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,06270852 0,09559289 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06270852 0,09551389 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06270852 0,09543501 ! renal system process GO:0003014 12 12 0,000 0,06270852 0,09535627 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06270852 0,09527766 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06270852 0,09519918 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06270852 0,09512082 ! pallium development GO:0021543 13 12 0,000 0,06270852 0,0950426 ! cell fate determination GO:0001709 12 12 0,000 0,06270852 0,0949645 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,06270852 0,09488654 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,06270852 0,0948087 ! somitogenesis GO:0001756 13 12 0,000 0,06270852 0,09473099 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06270852 0,0946534 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06270852 0,09457594 ! detection of light stimulus GO:0009583 13 12 0,000 0,06270852 0,09449861 ! synaptogenesis GO:0007416 12 12 0,000 0,06270852 0,09442141 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06270852 0,09434433 ! hormone transport GO:0009914 12 12 0,000 0,06270852 0,09426738 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06270852 0,09419055 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06270852 0,09411385 ! spermatid differentiation GO:0048515 13 12 0,000 0,06270852 0,09403727 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06270852 0,09396081 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06270852 0,09388449 ! neural tube closure GO:0001843 13 12 0,000 0,06270852 0,09380828 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,06270852 0,0937322 ! negative regulation of translation GO:0017148 12 12 0,000 0,06270852 0,09365624 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,06402133 0,09553953 ! microtubule-based movement GO:0007018 82 78 1,000 0,06548879 0,09765036 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,06548879 0,09757142 ! regulation of locomotion GO:0040012 79 79 1,000 0,06696766 0,09969418 ! regulation of cell motion GO:0051270 79 79 1,000 0,06696766 0,09961372 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,06775799 0,10070805 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,06775799 0,1006269 ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,06775799 0,10054588 ! phenol metabolic process GO:0018958 13 13 0,000 0,06775799 0,10046499 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,06775799 0,10038423 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,06775799 0,1003036 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,06775799 0,1002231 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,06775799 0,10014273 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,06775799 0,10006249 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,06775799 0,09998237 ! regeneration GO:0031099 13 13 0,000 0,06775799 0,09990239 ! keratinization GO:0031424 13 13 0,000 0,06775799 0,09982253 ! post-embryonic development GO:0009791 14 13 0,000 0,06775799 0,0997428 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,06775799 0,09966319 ! patterning of blood vessels GO:0001569 13 13 0,000 0,06775799 0,09958372 ! vasculogenesis GO:0001570 13 13 0,000 0,06775799 0,09950437 ! regulation of innate immune response GO:0045088 13 13 0,000 0,06775799 0,09942514 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,06775799 0,09934605 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,06775799 0,09926708 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,06775799 0,09918823 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,06775799 0,09910951 ! autophagy GO:0006914 13 13 0,000 0,06775799 0,09903091 ! receptor metabolic process GO:0043112 14 13 0,000 0,06775799 0,09895244 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,06775799 0,09887409 ! ureteric bud development GO:0001657 13 13 0,000 0,06775799 0,09879587 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,06775799 0,09871777 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,06775799 0,0986398 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,06775799 0,09856194 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,06775799 0,09848421 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,06775799 0,09840661 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,06775799 0,09832912 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,06775799 0,09825176 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,06775799 0,09817451 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,06775799 0,09809739 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,06775799 0,09802039 ! vasodilation GO:0042311 14 13 0,000 0,06775799 0,09794352 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,06775799 0,09786676 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,06775799 0,09779012 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,06775799 0,0977136 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,06775799 0,0976372 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,06775799 0,09756092 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,06775799 0,09748476 ! cell-cell junction organization GO:0045216 13 13 0,000 0,06775799 0,09740872 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,06775799 0,0973328 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 0,000 0,06775799 0,097257 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,06775799 0,09718131 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,06775799 0,09710574 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,06775799 0,09703029 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,06775799 0,09695495 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,06775799 0,09687974 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,06775799 0,09680464 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,06775799 0,09672965 ! blastocyst development GO:0001824 13 13 0,000 0,06775799 0,09665478 ! telomere organization GO:0032200 13 13 0,000 0,06775799 0,09658003 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,06775799 0,0965054 ! regulation of amine transport GO:0051952 13 13 0,000 0,06775799 0,09643087 ! neuron projection development GO:0031175 85 80 1,000 0,06845778 0,09735161 ! tube development GO:0035295 83 81 1,000 0,06995899 0,09940974 ! neuron fate commitment GO:0048663 14 14 0,000 0,072781 0,10334004 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,072781 0,10326049 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,072781 0,10318106 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,072781 0,10310175 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,072781 0,10302256 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,072781 0,1029435 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,072781 0,10286455 ! protein amino acid acylation GO:0043543 14 14 0,000 0,072781 0,10278573 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,072781 0,10270702 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,072781 0,10262844 ! vesicle docking GO:0048278 14 14 0,000 0,072781 0,10254998 ! superoxide metabolic process GO:0006801 15 14 0,000 0,072781 0,10247164 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,072781 0,10239342 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,072781 0,10231531 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,072781 0,10223733 ! hair cycle GO:0042633 14 14 0,000 0,072781 0,10215946 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,072781 0,10208172 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,072781 0,10200409 ! lysosome organization GO:0007040 14 14 0,000 0,072781 0,10192658 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,072781 0,10184918 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,072781 0,10177191 ! peptide transport GO:0015833 14 14 0,000 0,072781 0,10169475 ! primary neural tube formation GO:0014020 15 14 0,000 0,072781 0,10161771 ! peptide cross-linking GO:0018149 14 14 0,000 0,072781 0,10154078 ! regulation of behavior GO:0050795 14 14 0,000 0,072781 0,10146397 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,072781 0,10138728 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,072781 0,10131071 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,072781 0,10123424 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,072781 0,1011579 ! formation of primary germ layer GO:0001704 14 14 0,000 0,072781 0,10108167 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,072781 0,10100555 ! collagen fibril organization GO:0030199 14 14 0,000 0,072781 0,10092955 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,072781 0,10085367 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,072781 0,10077789 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,072781 0,10070223 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,072781 0,10062669 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,072781 0,10055126 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,072781 0,10047594 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,072781 0,10040073 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,072781 0,10032564 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,072781 0,10025065 ! regulation of cellular localization GO:0060341 86 85 1,000 0,07607173 0,10470515 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,07607173 0,10462701 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,07607173 0,10454899 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,07777766 0,10681388 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,07777766 0,10673435 ! positive regulation of ossification GO:0045778 15 15 0,000 0,07777766 0,10665493 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,07777766 0,10657563 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,07777766 0,10649646 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,07777766 0,10641739 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,07777766 0,10633845 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,07777766 0,10625962 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,07777766 0,10618091 ! ovarian follicle development GO:0001541 15 15 0,000 0,07777766 0,10610232 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,07777766 0,10602384 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,07777766 0,10594548 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,07777766 0,10586723 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,07777766 0,1057891 ! heme metabolic process GO:0042168 15 15 0,000 0,07777766 0,10571108 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,07777766 0,10563318 ! chromosome condensation GO:0030261 15 15 0,000 0,07777766 0,1055554 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,07777766 0,10547773 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,07777766 0,10540017 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,07777766 0,10532272 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,07777766 0,1052454 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,07777766 0,10516818 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,07777766 0,10509108 ! phospholipid transport GO:0015914 15 15 0,000 0,07777766 0,10501409 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,07777766 0,10493721 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,07777766 0,10486045 ! glutathione metabolic process GO:0006749 16 15 0,000 0,07777766 0,10478379 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,07777766 0,10470725 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,07777766 0,10463082 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,07777766 0,10455451 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,07777766 0,1044783 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 0,000 0,07777766 0,10440221 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,07777766 0,10432622 ! heart development GO:0007507 90 87 1,000 0,07919071 0,10614434 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,08274812 0,11083197 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,08274812 0,11075148 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,08274812 0,11067111 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,08274812 0,11059086 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,08274812 0,11051072 ! learning GO:0007612 16 16 0,000 0,08274812 0,1104307 ! circadian rhythm GO:0007623 16 16 0,000 0,08274812 0,11035079 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,08274812 0,110271 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,08274812 0,11019132 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,08274812 0,11011176 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,08274812 0,11003232 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,08274812 0,10995299 ! vesicle targeting GO:0006903 17 16 0,000 0,08274812 0,10987377 ! segmentation GO:0035282 17 16 0,000 0,08274812 0,10979467 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,08274812 0,10971568 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,08274812 0,1096368 ! iron ion homeostasis GO:0055072 16 16 0,000 0,08274812 0,10955804 ! positive regulation of cell development GO:0010720 16 16 0,000 0,08274812 0,10947939 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,08274812 0,10940085 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,08274812 0,10932243 ! cell fate specification GO:0001708 16 16 0,000 0,08274812 0,10924412 ! pentose metabolic process GO:0019321 16 16 0,000 0,08274812 0,10916592 ! fatty acid transport GO:0015908 16 16 0,000 0,08274812 0,10908783 ! cofactor catabolic process GO:0051187 16 16 0,000 0,08274812 0,10900986 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,08274812 0,10893199 ! polyol metabolic process GO:0019751 16 16 0,000 0,08274812 0,10885424 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,08274812 0,1087766 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,08274812 0,10869907 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,08274812 0,10862165 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,08274812 0,10854434 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,08274812 0,10846713 ! regulation of coagulation GO:0050818 17 16 0,000 0,08274812 0,10839004 ! brain development GO:0007420 91 90 1,000 0,08394409 0,10987852 ! DNA replication GO:0006260 91 91 1,000 0,08554795 0,11189841 ! visual perception GO:0007601 93 92 1,000 0,08716127 0,11392781 GO:0050953|sensory perception of light stimulus, ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,08769252 0,11454097 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,08769252 0,11445985 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,08769252 0,11437885 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,08769252 0,11429796 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,08769252 0,11421718 ! leukocyte adhesion GO:0007159 17 17 0,000 0,08769252 0,11413652 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,08769252 0,11405597 ! sensory perception of smell GO:0007608 17 17 0,000 0,08769252 0,11397554 ! tissue remodeling GO:0048771 17 17 0,000 0,08769252 0,11389521 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,08769252 0,11381501 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,08769252 0,11373491 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,08769252 0,11365493 ! neural crest cell development GO:0014032 19 17 0,000 0,08769252 0,11357506 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,08769252 0,1134953 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,08769252 0,11341566 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,08769252 0,11333612 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,08769252 0,1132567 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,08769252 0,11317739 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,08769252 0,11309819 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,08769252 0,1130191 ! pigmentation GO:0043473 17 17 0,000 0,08769252 0,11294012 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,08769252 0,11286125 ! adult locomotory behavior GO:0008344 17 17 0,000 0,08769252 0,11278249 ! embryonic organ development GO:0048568 17 17 0,000 0,08769252 0,11270384 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,08769252 0,1126253 ! liver development GO:0001889 17 17 0,000 0,08769252 0,11254687 ! gene silencing GO:0016458 17 17 0,000 0,08769252 0,11246855 ! pattern specification process GO:0007389 96 94 1,000 0,09041572 0,11588051 ! epidermis development GO:0008544 94 94 1,000 0,09041572 0,11579998 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09261098 0,11852919 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,09261098 0,11844693 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09261098 0,11836479 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09261098 0,11828276 ! membrane docking GO:0022406 18 18 0,000 0,09261098 0,11820085 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09261098 0,11811905 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,09261098 0,11803736 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,09261098 0,11795579 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09261098 0,11787433 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09261098 0,11779298 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,09261098 0,11771174 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09261098 0,11763062 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,09261098 0,11754961 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09261098 0,1174687 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09261098 0,11738791 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,09261098 0,11730724 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09261098 0,11722667 ! BMP signaling pathway GO:0030509 18 18 0,000 0,09261098 0,11714621 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09261098 0,11706586 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,09261098 0,11698563 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09261098 0,1169055 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,09750363 0,12299739 GO:0006956|complement activation, ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,09750363 0,12291326 ! feeding behavior GO:0007631 19 19 0,000 0,09750363 0,12282925 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,09750363 0,12274535 ! peroxisome organization GO:0007031 19 19 0,000 0,09750363 0,12266156 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,09750363 0,12257789 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,09750363 0,12249433 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,09750363 0,12241089 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,09750363 0,12232756 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,09750363 0,12224435 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,09750363 0,12216124 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,09750363 0,12207825 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,09750363 0,12199538 ! regulation of protein stability GO:0031647 19 19 0,000 0,09750363 0,12191261 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,09750363 0,12182996 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,09750363 0,12174742 ! eye morphogenesis GO:0048592 19 19 0,000 0,09750363 0,12166499 ! regulation of cell shape GO:0008360 21 19 0,000 0,09750363 0,12158267 ! placenta development GO:0001890 19 19 0,000 0,09750363 0,12150047 ! response to heat GO:0009408 19 19 0,000 0,09750363 0,12141837 ! vesicle localization GO:0051648 20 19 0,000 0,09750363 0,12133639 ! anti-apoptosis GO:0006916 100 99 1,000 0,09870765 0,12275183 ! ectoderm development GO:0007398 99 99 1,000 0,09870765 0,12266905 ! response to hormone stimulus GO:0009725 102 100 1,000 0,10039166 0,12467778 ! response to other organism GO:0051707 101 100 1,000 0,10039166 0,12459383 ! regulation of muscle development GO:0048634 21 20 0,000 0,10237061 0,12696436 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,10237061 0,12687898 ! organic ether metabolic process GO:0018904 20 20 0,000 0,10237061 0,12679371 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,10237061 0,12670855 ! neural tube development GO:0021915 21 20 0,000 0,10237061 0,12662352 ! nucleus organization GO:0006997 20 20 0,000 0,10237061 0,12653859 ! phagocytosis GO:0006909 21 20 0,000 0,10237061 0,12645378 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,10237061 0,12636908 ! protein targeting to membrane GO:0006612 22 20 0,000 0,10237061 0,1262845 ! chromatin remodeling GO:0006338 20 20 0,000 0,10237061 0,12620003 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,10237061 0,12611567 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,10237061 0,12603142 ! lipid oxidation GO:0034440 20 20 0,000 0,10237061 0,12594729 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,10237061 0,12586327 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,10237061 0,12577936 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,10237061 0,12569556 ! single fertilization GO:0007338 21 20 0,000 0,10237061 0,12561188 ! regulation of B cell activation GO:0050864 20 20 0,000 0,10237061 0,1255283 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,10721205 0,13137754 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,10721205 0,13129024 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,10721205 0,13120306 ! Notch signaling pathway GO:0007219 22 21 0,000 0,10721205 0,131116 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,10721205 0,13102905 ! organic anion transport GO:0015711 21 21 0,000 0,10721205 0,13094222 ! cholesterol transport GO:0030301 21 21 0,000 0,10721205 0,13085551 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,10721205 0,1307689 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,10721205 0,13068242 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,10721205 0,13059604 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,10721205 0,13050978 ! regulation of proteolysis GO:0030162 21 21 0,000 0,10721205 0,13042364 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,10721205 0,13033761 ! RNA export from nucleus GO:0006405 22 22 0,000 0,11202808 0,13610268 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,11202808 0,13601302 ! sister chromatid segregation GO:0000819 22 22 0,000 0,11202808 0,13592347 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,11202808 0,13583405 ! regulation of ion transport GO:0043269 22 22 0,000 0,11202808 0,13574475 ! odontogenesis GO:0042476 22 22 0,000 0,11202808 0,13565556 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,11202808 0,13556649 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,11202808 0,13547753 ! ovulation cycle process GO:0022602 22 22 0,000 0,11202808 0,13538869 ! spindle organization GO:0007051 22 22 0,000 0,11202808 0,13529997 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,11202808 0,13521137 ! cell chemotaxis GO:0060326 23 22 0,000 0,11202808 0,13512288 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,11202808 0,13503451 ! male sex differentiation GO:0046661 22 22 0,000 0,11202808 0,13494625 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,11202808 0,1348581 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,11202808 0,13477008 ! neuron migration GO:0001764 22 22 0,000 0,11202808 0,13468216 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,11202808 0,13459437 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,11202808 0,13450668 ! aerobic respiration GO:0009060 22 22 0,000 0,11202808 0,13441911 ! cytokinesis GO:0000910 23 22 0,000 0,11202808 0,13433166 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,11202808 0,13424432 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,11681883 0,13989416 ! viral infectious cycle GO:0019058 23 23 0,000 0,11681883 0,13980332 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,11681883 0,1397126 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,11681883 0,13962199 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,11681883 0,1395315 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,11681883 0,13944113 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,11681883 0,13935088 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,11681883 0,13926074 ! positive regulation of growth GO:0045927 23 23 0,000 0,11681883 0,13917072 ! female gonad development GO:0008585 23 23 0,000 0,11681883 0,13908082 ! lipid homeostasis GO:0055088 23 23 0,000 0,11681883 0,13899103 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,11681883 0,13890136 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,11681883 0,13881181 ! cell projection assembly GO:0030031 25 23 0,000 0,11681883 0,13872236 ! glucose homeostasis GO:0042593 24 24 0,000 0,12158443 0,14428854 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,12158443 0,14419569 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,12158443 0,14410296 ! ovulation cycle GO:0042698 24 24 0,000 0,12158443 0,14401035 ! fertilization GO:0009566 25 24 0,000 0,12158443 0,14391786 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,12158443 0,14382549 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,12158443 0,14373323 ! glucan metabolic process GO:0044042 25 24 0,000 0,12158443 0,14364109 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,12632501 0,14914605 ! negative regulation of secretion GO:0051048 26 25 0,000 0,12632501 0,14905057 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,12632501 0,1489552 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,12632501 0,14885996 ! cellular component disassembly GO:0022411 26 25 0,000 0,12632501 0,14876485 ! endosome transport GO:0016197 25 25 0,000 0,12632501 0,14866985 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,12632501 0,14857497 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,12632501 0,14848022 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,12632501 0,14838559 ! excretion GO:0007588 25 25 0,000 0,12632501 0,14829107 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,12632501 0,14819668 ! gastrulation GO:0007369 25 25 0,000 0,12632501 0,14810241 ! heart morphogenesis GO:0003007 25 25 0,000 0,12632501 0,14800825 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,12632501 0,14791422 ! regulation of endocytosis GO:0030100 25 25 0,000 0,12632501 0,14782031 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,12632501 0,14772651 ! positive regulation of defense response GO:0031349 26 26 0,000 0,13104068 0,15314393 ! glycolysis GO:0006096 26 26 0,000 0,13104068 0,15304688 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,13104068 0,15294996 ! cellular defense response GO:0006968 26 26 0,000 0,13104068 0,15285315 ! regulation of protein secretion GO:0050708 26 26 0,000 0,13104068 0,15275647 ! germ cell development GO:0007281 27 26 0,000 0,13104068 0,15265991 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,13104068 0,15256347 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,13104068 0,15246716 ! chloride transport GO:0006821 27 27 0,000 0,13573159 0,15782544 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,13573159 0,15772593 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,13573159 0,15762654 ! learning or memory GO:0007611 28 27 0,000 0,13573159 0,15752728 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,13573159 0,15742815 ! peptide metabolic process GO:0006518 29 27 0,000 0,13573159 0,15732914 ! mesenchymal cell development GO:0014031 29 27 0,000 0,13573159 0,15723025 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,13573159 0,15713149 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,13573159 0,15703285 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,14039786 0,16232952 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,14039786 0,16222775 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,14039786 0,1621261 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,14039786 0,16202458 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,14039786 0,16192319 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,14039786 0,16182192 ! histone modification GO:0016570 28 28 0,000 0,14039786 0,16172079 ! developmental growth GO:0048589 28 28 0,000 0,14039786 0,16161977 ! cartilage development GO:0051216 29 28 0,000 0,14039786 0,16151889 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,14503961 0,16675484 ! viral reproductive process GO:0022415 29 29 0,000 0,14503961 0,16665088 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,14503961 0,16654704 ! leukocyte migration GO:0050900 30 29 0,000 0,14503961 0,16644334 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,14503961 0,16633977 ! antigen processing and presentation GO:0019882 29 29 0,000 0,14503961 0,16623632 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,14503961 0,166133 ! tRNA processing GO:0008033 29 29 0,000 0,14503961 0,16602982 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,14503961 0,16592676 ! covalent chromatin modification GO:0016569 29 29 0,000 0,14503961 0,16582382 ! adult behavior GO:0030534 30 29 0,000 0,14503961 0,16572102 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,14503961 0,16561834 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,14503961 0,16551579 ! transition metal ion transport GO:0000041 31 30 0,000 0,14965697 0,17067933 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,14965697 0,17057378 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,14965697 0,17046836 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,14965697 0,17036306 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,14965697 0,1702579 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,14965697 0,17015287 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,14965697 0,17004796 ! response to temperature stimulus GO:0009266 30 30 0,000 0,14965697 0,16994319 ! regulation of ossification GO:0030278 30 30 0,000 0,14965697 0,16983855 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,14965697 0,16973403 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,14965697 0,16962964 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,14965697 0,16952538 ! vesicle organization GO:0016050 30 30 0,000 0,14965697 0,16942125 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,14965697 0,16931725 ! establishment of organelle localization GO:0051656 31 30 0,000 0,14965697 0,16921337 ! regulation of translational initiation GO:0006446 31 31 0,000 0,15425007 0,17429974 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,15425007 0,17419294 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,15425007 0,17408627 ! ion transmembrane transport GO:0034220 31 31 0,000 0,15425007 0,17397973 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,15425007 0,17387332 ! digestion GO:0007586 31 31 0,000 0,15425007 0,17376704 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,15425007 0,17366089 ! regulation of heart contraction GO:0008016 31 31 0,000 0,15425007 0,17355487 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,15425007 0,17344898 ! camera-type eye development GO:0043010 31 31 0,000 0,15425007 0,17334321 ! extracellular matrix organization GO:0030198 31 31 0,000 0,15425007 0,17323758 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,15425007 0,17313208 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,15425007 0,1730267 ! cell redox homeostasis GO:0045454 32 32 0,000 0,15881902 0,17804346 ! glucose catabolic process GO:0006007 32 32 0,000 0,15881902 0,17793523 ! lipid modification GO:0030258 32 32 0,000 0,15881902 0,17782713 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,15881902 0,17771915 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,15881902 0,17761132 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,15881902 0,17750361 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,15881902 0,17739603 ! nuclear export GO:0051168 32 32 0,000 0,15881902 0,17728858 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,15881902 0,17718126 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,15881902 0,17707408 ! amino acid transport GO:0006865 33 33 0,000 0,16336395 0,18203129 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,16336395 0,1819213 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,16336395 0,18181145 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,16336395 0,18170173 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,16336395 0,18159213 ! regulation of actin filament length GO:0030832 34 34 0,000 0,16788499 0,18650514 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,16788499 0,18639279 ! response to metal ion GO:0010038 34 34 0,000 0,16788499 0,18628057 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,16788499 0,18616849 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,16788499 0,18605654 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,16788499 0,18594473 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,16788499 0,18583305 ! secondary metabolic process GO:0019748 34 34 0,000 0,16788499 0,18572151 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,16788499 0,18561009 ! viral reproduction GO:0016032 34 34 0,000 0,16788499 0,18549882 ! acute inflammatory response GO:0002526 35 35 0,000 0,17238225 0,19035379 ! regulation of cellular component size GO:0032535 35 35 0,000 0,17238225 0,19023981 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,17238225 0,19012596 ! inorganic anion transport GO:0015698 35 35 0,000 0,17238225 0,19001225 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,17238225 0,18989867 ! regulation of immune effector process GO:0002697 35 35 0,000 0,17238225 0,18978523 ! hydrogen transport GO:0006818 36 36 0,000 0,17685586 0,19459424 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,17685586 0,19447813 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,17685586 0,19436216 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,17685586 0,19424633 ! regulation of mitosis GO:0007088 37 36 0,000 0,17685586 0,19413064 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,17685586 0,19401509 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,17685586 0,19389967 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,17685586 0,19378439 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,17685586 0,19366925 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,17685586 0,19355424 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,17685586 0,19343937 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,17685586 0,19332464 ! gonad development GO:0008406 36 36 0,000 0,17685586 0,19321004 ! regulation of lipase activity GO:0060191 36 36 0,000 0,17685586 0,19309558 ! activation of immune response GO:0002253 36 36 0,000 0,17685586 0,19298126 ! coagulation GO:0050817 39 36 0,000 0,17685586 0,19286707 GO:0007596|blood coagulation, ! eye development GO:0001654 37 37 0,000 0,18130593 0,1976031 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,18130593 0,19748631 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,18130593 0,19736966 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,18130593 0,19725315 ! positive regulation of secretion GO:0051047 39 38 0,000 0,1857326 0,20194996 ! neurotransmitter transport GO:0006836 40 38 0,000 0,1857326 0,20183089 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1857326 0,20171195 ! exocytosis GO:0006887 40 38 0,000 0,1857326 0,20159316 ! chromosome segregation GO:0007059 38 38 0,000 0,1857326 0,20147451 ! hexose catabolic process GO:0019320 38 38 0,000 0,1857326 0,20135599 ! RNA elongation GO:0006354 38 38 0,000 0,1857326 0,20123762 ! regulation of neurological system process GO:0031644 38 38 0,000 0,1857326 0,20111938 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,1857326 0,20100128 ! hemostasis GO:0007599 42 39 0,000 0,19013598 0,20564589 ! response to unfolded protein GO:0006986 39 39 0,000 0,19013598 0,20552528 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,19013598 0,20540481 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,19013598 0,20528448 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,19013598 0,20516429 ! limb development GO:0060173 39 39 0,000 0,19013598 0,20504424 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of cell motion GO:0051272 39 39 0,000 0,19013598 0,20492433 ! DNA catabolic process GO:0006308 41 40 0,000 0,19451618 0,20952269 ! organelle localization GO:0051640 41 40 0,000 0,19451618 0,2094003 ! amine catabolic process GO:0009310 42 41 0,000 0,19887333 0,21396588 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,19887333 0,21384104 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,19887333 0,21371635 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,19887333 0,21359181 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,19887333 0,21346741 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,20320754 0,21799272 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,20320754 0,21786591 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,20320754 0,21773924 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,20320754 0,21761273 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,20320754 0,21748635 ! alcohol catabolic process GO:0046164 43 43 0,000 0,20751894 0,22197179 ! humoral immune response GO:0006959 44 44 0,000 0,21180763 0,22642776 ! vitamin metabolic process GO:0006766 44 44 0,000 0,21180763 0,2262965 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,21180763 0,22616539 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,21607374 0,23058709 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,21607374 0,23045365 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,21607374 0,23032036 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,21607374 0,23018723 ! protein processing GO:0016485 45 45 0,000 0,21607374 0,23005425 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,22031738 0,23443703 ! tube morphogenesis GO:0035239 47 46 0,000 0,22031738 0,23430175 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,22031738 0,23416663 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,22453866 0,23851571 ! regulation of blood pressure GO:0008217 48 47 0,000 0,22453866 0,23837832 ! amine transport GO:0015837 47 47 0,000 0,22453866 0,23824108 ! rhythmic process GO:0048511 47 47 0,000 0,22453866 0,238104 ! regulation of catabolic process GO:0009894 48 47 0,000 0,22453866 0,23796708 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,22873771 0,24227793 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,22873771 0,24213877 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,23291463 0,24641886 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,23291463 0,24627748 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,23291463 0,24613627 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,23706953 0,25038346 ! chromatin assembly GO:0031497 50 50 0,000 0,23706953 0,25024006 GO:0006334|nucleosome assembly, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,23706953 0,25009682 ! transcription initiation GO:0006352 50 50 0,000 0,23706953 0,24995374 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,23706953 0,24981083 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,24120254 0,25402073 ! positive regulation of immune response GO:0050778 51 51 0,000 0,24120254 0,25387566 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,24120254 0,25373075 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,24120254 0,25358601 ! protein maturation GO:0051604 51 51 0,000 0,24120254 0,25344143 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,24531375 0,25761439 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,24531375 0,25746768 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,24531375 0,25732114 ! sodium ion transport GO:0006814 53 53 0,000 0,2494033 0,26146204 ! tRNA metabolic process GO:0006399 53 53 0,000 0,2494033 0,2613134 ! response to hypoxia GO:0001666 53 53 0,000 0,2494033 0,26116493 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,2494033 0,26101662 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,2494033 0,26086849 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,25347127 0,26497309 ! response to oxygen levels GO:0070482 55 54 0,000 0,25347127 0,26482288 ! hormone metabolic process GO:0042445 55 54 0,000 0,25347127 0,26467284 ! sulfur metabolic process GO:0006790 55 54 0,000 0,25347127 0,26452296 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,25347127 0,26437326 ! nucleosome organization GO:0034728 55 55 0,000 0,2575178 0,26844191 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,2575178 0,26829016 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,2575178 0,26813859 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,26154297 0,272176 ! ATP metabolic process GO:0046034 57 57 0,000 0,26554692 0,27618678 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,26554692 0,276031 ! dephosphorylation GO:0016311 60 59 0,000 0,27349153 0,28412903 ! carboxylic acid transport GO:0046942 59 59 0,000 0,27349153 0,28396896 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,27349153 0,28380906 ! sterol metabolic process GO:0016125 59 59 0,000 0,27349153 0,28364935 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,27349153 0,28348982 ! potassium ion transport GO:0006813 60 60 0,000 0,27743243 0,28741313 ! cellular respiration GO:0045333 62 61 0,000 0,28135251 0,2913105 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,28135251 0,29114693 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,28525191 0,29501642 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,28525191 0,29485096 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,28525191 0,29468568 ! regulation of secretion GO:0051046 65 63 0,000 0,28913071 0,29852543 ! glucose metabolic process GO:0006006 63 63 0,000 0,28913071 0,29835828 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,28913071 0,29819132 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,28913071 0,29802455 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,29298903 0,30183274 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,29298903 0,30166412 ! angiogenesis GO:0001525 65 64 0,000 0,29298903 0,30149569 ! anion transport GO:0006820 65 65 0,000 0,29682697 0,30527461 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,29682697 0,30510435 ! regulation of hormone levels GO:0010817 66 65 0,000 0,29682697 0,30493428 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,30064464 0,30868416 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,30064464 0,30851229 ! DNA packaging GO:0006323 66 66 0,000 0,30064464 0,3083406 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,30064464 0,30816911 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,30444213 0,31188819 ! muscle contraction GO:0006936 67 67 0,000 0,30444213 0,31171492 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,30444213 0,31154184 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,30821957 0,31523233 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,30821957 0,31505749 ! regulation of translation GO:0006417 69 69 0,000 0,31197703 0,31872155 ! positive regulation of transport GO:0051050 71 70 0,000 0,31571464 0,32236127 ! translational elongation GO:0006414 71 71 0,000 0,31943249 0,32597679 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,31943249 0,32579639 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,31943249 0,3256162 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 0,000 0,32313069 0,3292039 ! muscle system process GO:0003012 72 72 0,000 0,32313069 0,32902202 ! electron transport chain GO:0022900 75 74 0,000 0,33046851 0,33630782 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,33046851 0,33612222 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,33410833 0,33963688 ! response to oxidative stress GO:0006979 76 75 0,000 0,33410833 0,33944965 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,33410833 0,33926262 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,3377289 0,3427502 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,34133032 0,34621452 ! metal ion homeostasis GO:0055065 78 78 0,000 0,34491268 0,3496557 ! regulation of immune response GO:0050776 78 78 0,000 0,34491268 0,34946348 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,35202061 0,35646922 ! lipid catabolic process GO:0016042 82 81 0,000 0,35554638 0,35984183 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,36254201 0,3667206 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,36254201 0,36651943 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,36601206 0,36982469 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,37289712 0,37657501 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,37289712 0,37636878 ! male gamete generation GO:0048232 90 88 0,000 0,3797094 0,38303472 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,3797094 0,38282518 ! chemotaxis GO:0006935 90 89 0,000 0,38308849 0,38602082 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,38308849 0,38580988 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,38644966 0,38898237 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,38979301 0,39213347 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,39311864 0,39526331 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,39311864 0,39504779 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,39311864 0,3948325 ! blood vessel development GO:0001568 95 94 0,000 0,39971706 0,40124104 ! cofactor metabolic process GO:0051186 95 94 0,000 0,39971706 0,40102262 ! vasculature development GO:0001944 97 96 0,000 0,40624566 0,40735079 ! endocytosis GO:0006897 99 98 0,000 0,41270516 0,41360283 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,41270516 0,41337805 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,41270516 0,41315351 ! blood circulation GO:0008015 99 98 0,000 0,41270516 0,41292921 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,41270516 0,41270516