pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6388-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 11,000 2,478E-14 5,961E-11 ! interphase GO:0051325 213 98 11,000 3,639E-14 4,378E-11 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 4,005E-11 3,212E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 2,43E-10 1,461E-07 ! cell cycle checkpoint GO:0000075 137 69 6,000 3,421E-08 1,646E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 7,997E-08 3,207E-05 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 4,000 9,959E-08 3,423E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 1,228E-07 3,695E-05 GO:0045936|negative regulation of phosphate metabolic process, ! cell cycle arrest GO:0007050 213 100 6,000 4,503E-07 1,204E-04 ! L-serine biosynthetic process GO:0006564 6 5 2,000 9,765E-07 2,349E-04 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 3,000 1,642E-06 3,592E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 1,687E-06 3,383E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 2,045E-06 3,785E-04 ! activation of caspase activity GO:0006919 84 48 4,000 2,946E-06 5,062E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 3,394E-06 5,445E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 3,394E-06 5,104E-04 ! negative regulation of cell development GO:0010721 73 25 3,000 5,244E-06 7,422E-04 GO:0050768|negative regulation of neurogenesis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 5,413E-06 7,235E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 5,413E-06 6,854E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 5,413E-06 6,511E-04 ! positive regulation of caspase activity GO:0043280 95 55 4,000 5,83E-06 6,68E-04 GO:0010952|positive regulation of peptidase activity, ! insulin receptor signaling pathway GO:0008286 64 26 3,000 6,176E-06 6,754E-04 ! middle ear morphogenesis GO:0042474 14 9 2,000 8,091E-06 8,464E-04 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 8,984E-06 9,006E-04 ! ear development GO:0043583 103 62 4,000 1,057E-05 1,017E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 1,152E-05 1,066E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 1,548E-05 1,379E-03 ! DNA damage checkpoint GO:0000077 71 33 3,000 1,648E-05 1,416E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 1,788E-05 1,483E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,098E-05 1,682E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of caspase activity GO:0043281 122 72 4,000 2,201E-05 1,708E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 4,000 2,201E-05 1,655E-03 ! DNA integrity checkpoint GO:0031570 75 36 3,000 2,347E-05 1,711E-03 ! regulation of endopeptidase activity GO:0052548 125 74 4,000 2,515E-05 1,78E-03 ! meiosis I GO:0007127 65 37 3,000 2,622E-05 1,803E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 2,622E-05 1,752E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 2,717E-05 1,767E-03 ! mammary gland development GO:0030879 86 39 3,000 3,242E-05 2,053E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 3,447E-05 2,126E-03 ! regulation of peptidase activity GO:0052547 134 79 4,000 3,454E-05 2,078E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 3,454E-05 2,027E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 3,898E-05 2,233E-03 GO:0045937|positive regulation of phosphate metabolic process, ! G1/S transition checkpoint GO:0031575 40 15 2,000 4,294E-05 2,403E-03 ! negative regulation of growth GO:0045926 155 84 4,000 4,644E-05 2,54E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 5,267E-05 2,816E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 5,267E-05 2,755E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 5,747E-05 2,942E-03 ! cell growth GO:0016049 84 45 3,000 5,747E-05 2,881E-03 ! positive regulation of protein modification process GO:0031401 136 88 4,000 5,806E-05 2,851E-03 ! gland development GO:0048732 206 88 4,000 5,806E-05 2,794E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 6,272E-05 2,959E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 6,374E-05 2,949E-03 ! G1 phase GO:0051318 40 19 2,000 9,021E-05 4,095E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 9,238E-05 4,116E-03 ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 1,058E-04 4,627E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,058E-04 4,544E-03 ! response to UV GO:0009411 104 53 3,000 1,097E-04 4,633E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 1,23E-04 5,101E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,23E-04 5,015E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 2,000 1,23E-04 4,931E-03 ! aging GO:0007568 103 55 3,000 1,269E-04 5,006E-03 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 1,419E-04 5,507E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,419E-04 5,419E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 1,669E-04 6,276E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 1,852E-04 6,857E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 1,9E-04 6,928E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 2,098E-04 7,533E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 2,098E-04 7,423E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 2,098E-04 7,315E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 2,098E-04 7,211E-03 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 1,000 2,126E-04 7,204E-03 ! positive regulation of helicase activity GO:0051096 11 5 1,000 2,126E-04 7,104E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,126E-04 7,007E-03 ! endochondral ossification GO:0001958 16 5 1,000 2,126E-04 6,912E-03 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 2,126E-04 6,82E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,126E-04 6,73E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 2,126E-04 6,643E-03 ! stem cell division GO:0017145 11 5 1,000 2,126E-04 6,558E-03 GO:0048103|somatic stem cell division, ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 2,65E-04 8,07E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,732E-04 8,216E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,892E-04 8,59E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 2,958E-04 8,678E-03 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 3,179E-04 9,216E-03 ! regulation of interferon-beta production GO:0032648 8 6 1,000 3,179E-04 9,106E-03 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! neuron remodeling GO:0016322 15 6 1,000 3,179E-04 8,999E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 3,179E-04 8,894E-03 ! hyperosmotic response GO:0006972 9 6 1,000 3,179E-04 8,792E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 3,179E-04 8,692E-03 GO:0045686|negative regulation of glial cell differentiation, ! response to exogenous dsRNA GO:0043330 10 6 1,000 3,179E-04 8,594E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 3,179E-04 8,499E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 3,179E-04 8,406E-03 ! negative regulation of axon extension GO:0030517 21 6 1,000 3,179E-04 8,314E-03 ! determination of adult lifespan GO:0008340 15 6 1,000 3,179E-04 8,225E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,179E-04 8,137E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 3,288E-04 8,327E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,601E-04 9,026E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 3,641E-04 9,03E-03 ! meiosis GO:0007126 121 74 3,000 3,999E-04 9,818E-03 GO:0051327|M phase of meiotic cell cycle, ! serine family amino acid metabolic process GO:0009069 49 31 2,000 4,017E-04 9,763E-03 ! meiotic cell cycle GO:0051321 122 75 3,000 4,209E-04 0,01012746 ! prostate gland development GO:0030850 13 7 1,000 4,437E-04 0,01057032 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 4,437E-04 0,01046669 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,437E-04 0,01036507 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 4,437E-04 0,01026541 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 4,437E-04 0,01016764 ! rRNA modification GO:0000154 14 7 1,000 4,437E-04 0,01007172 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 4,437E-04 9,978E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,437E-04 9,885E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,437E-04 9,795E-03 ! response to tumor cell GO:0002347 13 7 1,000 4,437E-04 9,705E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 4,437E-04 9,618E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 5,129E-04 0,01101871 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 5,77E-04 0,01228592 ! negative regulation of cell adhesion GO:0007162 81 35 2,000 5,77E-04 0,01217815 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 5,898E-04 0,01234025 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 1,000 5,898E-04 0,01223387 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,898E-04 0,01212931 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,898E-04 0,01202652 ! ER overload response GO:0006983 12 8 1,000 5,898E-04 0,01192546 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,898E-04 0,01182608 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 5,898E-04 0,01172834 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 5,898E-04 0,01163221 ! osteoblast development GO:0002076 16 8 1,000 5,898E-04 0,01153764 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 5,898E-04 0,01144459 ! multicellular organismal aging GO:0010259 18 8 1,000 5,898E-04 0,01135303 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 5,907E-04 0,01127973 ! negative regulation of cell activation GO:0050866 65 36 2,000 6,273E-04 0,01188492 ! regulation of ligase activity GO:0051340 142 84 3,000 6,47E-04 0,0121615 ! negative regulation of DNA binding GO:0043392 68 37 2,000 6,804E-04 0,01268992 ! mitochondrion organization GO:0007005 148 86 3,000 7,07E-04 0,01308462 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 7,362E-04 0,01352131 ! nucleus organization GO:0006997 67 38 2,000 7,362E-04 0,01341887 ! RNA methylation GO:0001510 15 9 1,000 7,56E-04 0,01367694 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 7,56E-04 0,01357487 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 7,56E-04 0,01347432 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 7,56E-04 0,01337524 ! regulation of type I interferon production GO:0032479 12 9 1,000 7,56E-04 0,01327761 ! motor axon guidance GO:0008045 16 9 1,000 7,56E-04 0,0131814 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 7,56E-04 0,01308657 ! regulation of telomere maintenance GO:0032204 14 9 1,000 7,56E-04 0,01299309 ! regulation of DNA binding GO:0051101 155 88 3,000 7,708E-04 0,01315284 ! ear morphogenesis GO:0042471 60 39 2,000 7,948E-04 0,0134676 ! regulation of cell adhesion GO:0030155 212 89 3,000 8,042E-04 0,01353066 ! negative regulation of binding GO:0051100 72 40 2,000 8,564E-04 0,01430872 ! regulation of T cell proliferation GO:0042129 71 41 2,000 9,209E-04 0,01527997 ! regulation of T cell differentiation GO:0045580 70 41 2,000 9,209E-04 0,01517531 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 9,422E-04 0,01542083 ! lung alveolus development GO:0048286 26 10 1,000 9,422E-04 0,01531664 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 9,422E-04 0,01521384 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 1,000 9,422E-04 0,01511241 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 9,422E-04 0,01501233 ! regulation of gliogenesis GO:0014013 23 10 1,000 9,422E-04 0,01491357 GO:0045685|regulation of glial cell differentiation, ! negative regulation of axonogenesis GO:0050771 32 10 1,000 9,422E-04 0,01481609 ! response to dsRNA GO:0043331 20 10 1,000 9,422E-04 0,01471988 ! natural killer cell mediated immunity GO:0002228 18 10 1,000 9,422E-04 0,01462492 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 9,883E-04 0,01524326 ! forebrain development GO:0030900 188 95 3,000 1,026E-03 0,01572759 ! epithelial cell differentiation GO:0030855 79 43 2,000 1,059E-03 0,01612432 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,133E-03 0,01713713 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,148E-03 0,01726356 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,148E-03 0,01715633 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of intracellular pH GO:0051453 19 11 1,000 1,148E-03 0,01705043 ! neuroblast proliferation GO:0007405 24 11 1,000 1,148E-03 0,01694582 ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 1,148E-03 0,0168425 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 1,148E-03 0,01674042 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! positive regulation of JNK cascade GO:0046330 23 11 1,000 1,148E-03 0,01663957 ! regulation of JNK cascade GO:0046328 94 47 2,000 1,373E-03 0,01977434 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 1,373E-03 0,0196697 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,373E-03 0,01955331 ! hippocampus development GO:0021766 26 12 1,000 1,373E-03 0,01943829 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,373E-03 0,01932462 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 1,000 1,373E-03 0,01921227 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 1,373E-03 0,01910121 ! focal adhesion formation GO:0048041 35 12 1,000 1,373E-03 0,01899144 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 1,000 1,373E-03 0,01888291 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 1,373E-03 0,01877563 ! leukocyte mediated cytotoxicity GO:0001909 26 12 1,000 1,373E-03 0,01866955 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,459E-03 0,01972224 ! cellular component disassembly GO:0022411 86 48 2,000 1,459E-03 0,01961206 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,459E-03 0,01950311 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 1,459E-03 0,01939535 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,459E-03 0,01928879 ! regulation of chemokine production GO:0032642 18 13 1,000 1,618E-03 0,02127564 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 1,618E-03 0,02116001 ! endocrine pancreas development GO:0031018 22 13 1,000 1,618E-03 0,02104563 ! response to X-ray GO:0010165 25 13 1,000 1,618E-03 0,02093249 ! regulation of cellular pH GO:0030641 22 13 1,000 1,618E-03 0,02082055 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,618E-03 0,0207098 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,618E-03 0,02060022 ! inner ear development GO:0048839 79 50 2,000 1,642E-03 0,0207966 ! negative regulation of immune system process GO:0002683 95 50 2,000 1,642E-03 0,02068771 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 1,739E-03 0,02179233 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 1,739E-03 0,02167941 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,739E-03 0,02156767 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 2,000 1,839E-03 0,02269384 ! lactation GO:0007595 26 14 1,000 1,882E-03 0,02310473 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,882E-03 0,02298745 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 1,882E-03 0,02287135 ! response to gamma radiation GO:0010332 28 14 1,000 1,882E-03 0,02275642 ! regulation of axon extension GO:0030516 37 14 1,000 1,882E-03 0,02264264 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,165E-03 0,02591707 ! cell killing GO:0001906 29 15 1,000 2,165E-03 0,02578876 ! regulation of DNA replication GO:0006275 101 56 2,000 2,276E-03 0,02697566 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,467E-03 0,02909518 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 2,467E-03 0,02895326 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,467E-03 0,02881271 ! response to osmotic stress GO:0006970 25 16 1,000 2,467E-03 0,02867352 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,467E-03 0,02853566 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,467E-03 0,02839913 ! DNA catabolic process GO:0006308 86 59 2,000 2,642E-03 0,03027304 ! limbic system development GO:0021761 36 17 1,000 2,787E-03 0,0317837 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,787E-03 0,03163377 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 2,787E-03 0,03148526 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 2,787E-03 0,03133813 ! neuron maturation GO:0042551 42 18 1,000 3,126E-03 0,0349848 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,126E-03 0,03482283 ! response to retinoic acid GO:0032526 26 18 1,000 3,126E-03 0,03466235 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,126E-03 0,03450335 ! detection of external stimulus GO:0009581 91 63 2,000 3,184E-03 0,0349842 ! lymphocyte mediated immunity GO:0002449 114 64 2,000 3,33E-03 0,03641477 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 3,479E-03 0,03787601 ! lipid phosphorylation GO:0046834 35 19 1,000 3,483E-03 0,03775273 ! cellular response to unfolded protein GO:0034620 33 19 1,000 3,483E-03 0,03758344 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 1,000 3,483E-03 0,03741565 ! actin filament bundle formation GO:0051017 42 19 1,000 3,483E-03 0,03724936 ! neuromuscular junction development GO:0007528 34 19 1,000 3,483E-03 0,03708454 ! plasma membrane fusion GO:0045026 28 19 1,000 3,483E-03 0,03692117 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,483E-03 0,03675924 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 3,483E-03 0,03659872 ! actin filament organization GO:0007015 148 66 2,000 3,632E-03 0,03799853 ! regulation of cellular response to stress GO:0080135 128 67 2,000 3,79E-03 0,03947414 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 3,79E-03 0,03930399 ! cAMP metabolic process GO:0046058 36 20 1,000 3,859E-03 0,03984578 ! response to vitamin GO:0033273 31 20 1,000 3,859E-03 0,0396755 ! response to alkaloid GO:0043279 38 20 1,000 3,859E-03 0,03950666 ! pancreas development GO:0031016 35 20 1,000 3,859E-03 0,03933926 ! cellular response to starvation GO:0009267 33 20 1,000 3,859E-03 0,03917328 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 3,859E-03 0,03900868 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 3,859E-03 0,03884547 ! negative regulation of translation GO:0017148 29 20 1,000 3,859E-03 0,03868361 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,859E-03 0,0385231 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 4,117E-03 0,04093371 ! urogenital system development GO:0001655 137 69 2,000 4,117E-03 0,04076526 ! axis specification GO:0009798 38 21 1,000 4,252E-03 0,04192702 ! cell aging GO:0007569 44 21 1,000 4,252E-03 0,04175589 ! detection of biotic stimulus GO:0009595 29 21 1,000 4,252E-03 0,04158615 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,252E-03 0,04141778 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 4,252E-03 0,04125077 ! B cell activation GO:0042113 160 71 2,000 4,461E-03 0,04310646 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 4,461E-03 0,04293403 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 4,639E-03 0,04447215 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 4,639E-03 0,04429567 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,663E-03 0,04434414 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 4,663E-03 0,04416956 ! activation of JUN kinase activity GO:0007257 42 22 1,000 4,663E-03 0,04399635 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 4,663E-03 0,04382449 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 4,663E-03 0,04365396 ! regulation of transcription factor activity GO:0051090 126 74 2,000 5,009E-03 0,04671052 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 2,000 5,009E-03 0,04653017 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,092E-03 0,04711648 ! gluconeogenesis GO:0006094 33 23 1,000 5,092E-03 0,04693595 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 5,092E-03 0,04675681 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 5,092E-03 0,04657903 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 5,092E-03 0,04640259 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 5,092E-03 0,04622749 ! cell-matrix adhesion GO:0007160 163 75 2,000 5,2E-03 0,04703479 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 5,538E-03 0,04990049 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 5,538E-03 0,04971429 GO:0016444|somatic cell DNA recombination, ! pallium development GO:0021543 49 24 1,000 5,538E-03 0,04952948 ! protein tetramerization GO:0051262 52 24 1,000 5,538E-03 0,04934604 ! positive regulation of ligase activity GO:0051351 124 77 2,000 5,595E-03 0,04967726 ! myelination GO:0042552 45 25 1,000 6,001E-03 0,05308124 ! negative regulation of DNA replication GO:0008156 42 25 1,000 6,001E-03 0,05288681 ! response to starvation GO:0042594 42 25 1,000 6,001E-03 0,05269379 ! osteoblast differentiation GO:0001649 60 25 1,000 6,001E-03 0,05250218 ! immunoglobulin production GO:0002377 55 25 1,000 6,001E-03 0,05231195 GO:0002440|production of molecular mediator of immune response, ! activation of protein kinase activity GO:0032147 147 79 2,000 6,008E-03 0,05218812 ! protein import into nucleus GO:0006606 158 80 2,000 6,221E-03 0,05384497 ! cell-substrate adhesion GO:0031589 171 81 2,000 6,439E-03 0,05552848 ! nuclear import GO:0051170 161 81 2,000 6,439E-03 0,05533016 ! regulation of neuron differentiation GO:0045664 167 81 2,000 6,439E-03 0,05513326 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 6,481E-03 0,05529747 ! pyruvate metabolic process GO:0006090 38 26 1,000 6,481E-03 0,05510207 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 6,481E-03 0,05490805 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 6,481E-03 0,05471539 ! somatic diversification of immune receptors GO:0002200 56 26 1,000 6,481E-03 0,05452408 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 6,481E-03 0,0543341 ! response to drug GO:0042493 143 82 2,000 6,661E-03 0,05564859 ! response to nutrient GO:0007584 125 82 2,000 6,661E-03 0,05545604 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 6,979E-03 0,05789791 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 6,979E-03 0,05769895 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 1,000 6,979E-03 0,05750135 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! fat cell differentiation GO:0045444 50 27 1,000 6,979E-03 0,0573051 ! mitochondrial membrane organization GO:0007006 57 27 1,000 6,979E-03 0,05711018 ! base-excision repair GO:0006284 41 27 1,000 6,979E-03 0,05691659 ! regulation of chromosome organization GO:0033044 42 27 1,000 6,979E-03 0,0567243 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 6,979E-03 0,05653331 ! negative regulation of protein modification process GO:0031400 60 28 1,000 7,493E-03 0,06049404 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 1,000 7,493E-03 0,06029171 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 7,493E-03 0,06009074 ! amine biosynthetic process GO:0009309 138 86 2,000 7,595E-03 0,06070871 ! protein localization in nucleus GO:0034504 176 87 2,000 7,84E-03 0,06245857 ! regulation of pH GO:0006885 43 29 1,000 8,023E-03 0,06370949 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 8,023E-03 0,06349992 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 8,023E-03 0,06329173 ! tissue homeostasis GO:0001894 48 29 1,000 8,023E-03 0,06308489 GO:0048871|multicellular organismal homeostasis, ! cellular defense response GO:0006968 114 89 2,000 8,343E-03 0,0653883 ! cell junction assembly GO:0034329 78 30 1,000 8,57E-03 0,06694891 ! ensheathment of neurons GO:0007272 57 30 1,000 8,57E-03 0,06673225 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 50 30 1,000 8,57E-03 0,06651698 ! iron ion homeostasis GO:0055072 54 31 1,000 9,134E-03 0,0706614 ! erythrocyte differentiation GO:0030218 55 31 1,000 9,134E-03 0,07043492 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 9,134E-03 0,07020989 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 9,407E-03 0,07207773 ! transcription initiation GO:0006352 153 94 2,000 9,684E-03 0,07396913 ! regulation of T cell activation GO:0050863 158 94 2,000 9,684E-03 0,07373505 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 9,713E-03 0,07372203 ! metanephros development GO:0001656 74 32 1,000 9,713E-03 0,0734902 ! response to ionizing radiation GO:0010212 65 32 1,000 9,713E-03 0,07325982 ! response to mechanical stimulus GO:0009612 57 32 1,000 9,713E-03 0,07303088 ! regulation of axonogenesis GO:0050770 75 32 1,000 9,713E-03 0,07280337 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 9,713E-03 0,07257728 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 1,000 9,713E-03 0,07235258 ! hexose biosynthetic process GO:0019319 48 32 1,000 9,713E-03 0,07212927 ! peripheral nervous system development GO:0007422 64 32 1,000 9,713E-03 0,07190733 ! detection of stimulus GO:0051606 151 96 2,000 0,01025364 0,07567565 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01030858 0,07584845 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01030858 0,07561721 ! glial cell differentiation GO:0010001 63 34 1,000 0,01091978 0,07985713 ! mismatch repair GO:0006298 46 34 1,000 0,01091978 0,07961513 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01154662 0,08393099 ! telencephalon development GO:0021537 68 35 1,000 0,01154662 0,08367818 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01154662 0,0834269 ! cytokine production GO:0001816 59 35 1,000 0,01154662 0,08317712 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01154662 0,08292883 ! cell junction organization GO:0034330 86 36 1,000 0,01218893 0,08728141 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01218893 0,08702242 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01218893 0,08676496 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01218893 0,08650901 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01218893 0,08625457 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01284656 0,09064169 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 0,01284656 0,09037665 ! regulation of protein stability GO:0031647 73 37 1,000 0,01284656 0,09011317 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,01351935 0,09455688 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01351935 0,0942828 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01351935 0,09401031 ! mRNA catabolic process GO:0006402 71 39 1,000 0,01420717 0,09850848 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01420717 0,09822541 ! RNA modification GO:0009451 57 39 1,000 0,01420717 0,09794396 ! maintenance of protein location GO:0045185 91 40 1,000 0,01490984 0,10249449 ! gliogenesis GO:0042063 88 41 1,000 0,01562722 0,10711993 ! T cell differentiation GO:0030217 81 41 1,000 0,01562722 0,10681561 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,01562722 0,10651302 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01635917 0,11118687 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01635917 0,11087367 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01635917 0,11056223 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01635917 0,11025253 ! glucose transport GO:0015758 65 43 1,000 0,01710552 0,11496057 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01710552 0,11464035 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 0,01786614 0,11940538 ! hexose transport GO:0008645 67 44 1,000 0,01786614 0,11907462 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01786614 0,11874568 ! double-strand break repair GO:0006302 81 44 1,000 0,01786614 0,11841856 ! biopolymer methylation GO:0043414 84 44 1,000 0,01786614 0,11809323 ! B cell differentiation GO:0030183 107 44 1,000 0,01786614 0,11776969 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01786614 0,11744792 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01864088 0,12220696 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,01864088 0,12187488 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,01942959 0,12668723 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01942959 0,12634483 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01942959 0,12600428 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01942959 0,12566556 ! pigmentation GO:0043473 100 46 1,000 0,01942959 0,12532866 ! response to calcium ion GO:0051592 81 47 1,000 0,02023212 0,13015639 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02023212 0,12980931 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,02023212 0,12946407 ! JNK cascade GO:0007254 91 47 1,000 0,02023212 0,12912066 ! methylation GO:0032259 90 47 1,000 0,02023212 0,12877907 ! mitochondrial transport GO:0006839 82 48 1,000 0,02104834 0,13362088 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,02104834 0,13326924 ! regulation of action potential GO:0001508 95 49 1,000 0,0218781 0,13815936 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,0218781 0,13779768 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,0218781 0,1374379 ! endocrine system development GO:0035270 104 49 1,000 0,0218781 0,13707999 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,0218781 0,13672393 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0218781 0,13636973 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,02272126 0,14125931 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02302912 0,14280426 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02302912 0,14243715 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! neuron fate determination GO:0048664 7 5 0,000 0,02302912 0,14207193 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02302912 0,14170857 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02302912 0,14134707 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02302912 0,14098741 ! polyol transport GO:0015791 12 5 0,000 0,02302912 0,14062957 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02302912 0,14027355 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02302912 0,13991932 ! response to superoxide GO:0000303 10 5 0,000 0,02302912 0,13956688 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02302912 0,13921621 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02302912 0,1388673 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02302912 0,13852013 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02302912 0,13817469 ! female meiosis GO:0007143 7 5 0,000 0,02302912 0,13783097 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02302912 0,13748896 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02302912 0,13714864 ! cobalt ion transport GO:0006824 11 5 0,000 0,02302912 0,13681 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02302912 0,13647303 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02302912 0,13613772 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02302912 0,13580405 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02302912 0,13547201 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02302912 0,13514159 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02302912 0,13481278 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02302912 0,13448556 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02302912 0,13415993 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02302912 0,13383587 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02302912 0,13351338 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02302912 0,13319243 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02302912 0,13287302 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02302912 0,13255515 ! negative chemotaxis GO:0050919 14 5 0,000 0,02302912 0,13223879 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02302912 0,13192393 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02302912 0,13161057 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02302912 0,1312987 ! behavioral response to pain GO:0048266 9 5 0,000 0,02302912 0,1309883 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02302912 0,13067937 ! Notch receptor processing GO:0007220 8 5 0,000 0,02302912 0,13037188 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02302912 0,13006585 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02302912 0,12976124 ! micturition GO:0060073 9 5 0,000 0,02302912 0,12945806 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02302912 0,1291563 ! copulation GO:0007620 9 5 0,000 0,02302912 0,12885593 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02302912 0,12855696 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02302912 0,12825938 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02302912 0,12796317 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02302912 0,12766832 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02302912 0,12737483 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02302912 0,12708269 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02302912 0,12679188 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02302912 0,1265024 ! grooming behavior GO:0007625 6 5 0,000 0,02302912 0,12621424 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02302912 0,12592739 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02302912 0,12564184 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02302912 0,12535758 ! response to protozoan GO:0001562 10 5 0,000 0,02302912 0,12507461 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02302912 0,12479291 ! lymph vessel development GO:0001945 10 5 0,000 0,02302912 0,12451247 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02302912 0,1242333 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02302912 0,12395537 ! parathyroid gland development GO:0060017 13 5 0,000 0,02302912 0,12367869 ! anagen GO:0042640 6 5 0,000 0,02302912 0,12340323 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02302912 0,123129 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02302912 0,12285599 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02302912 0,12258418 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02302912 0,12231358 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02302912 0,12204417 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02302912 0,12177594 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02302912 0,12150888 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02302912 0,121243 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02302912 0,12097828 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02302912 0,12071471 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02302912 0,12045228 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02302912 0,120191 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02302912 0,11993085 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02302912 0,11967182 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02302912 0,1194139 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02302912 0,1191571 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02302912 0,1189014 ! histidine catabolic process GO:0006548 6 5 0,000 0,02302912 0,11864679 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02302912 0,11839327 ! microvillus organization GO:0032528 7 5 0,000 0,02302912 0,11814083 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02302912 0,11788947 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02302912 0,11763917 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02302912 0,11738994 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02302912 0,11714176 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02302912 0,11689462 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02302912 0,11664853 ! polyol catabolic process GO:0046174 7 5 0,000 0,02302912 0,11640347 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02302912 0,11615944 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02302912 0,11591642 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02302912 0,11567443 ! muscle cell migration GO:0014812 8 5 0,000 0,02302912 0,11543344 ! mitochondrial fission GO:0000266 8 5 0,000 0,02302912 0,11519345 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02302912 0,11495446 ! mRNA transcription GO:0009299 9 5 0,000 0,02302912 0,11471646 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02302912 0,11447944 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02302912 0,1142434 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02302912 0,11400834 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02302912 0,11377423 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02302912 0,11354109 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02302912 0,1133089 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02302912 0,11307766 ! response to food GO:0032094 6 5 0,000 0,02302912 0,11284735 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02302912 0,11261799 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02302912 0,11238956 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02302912 0,11216205 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02302912 0,11193546 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02302912 0,11170978 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02302912 0,11148501 ! forebrain neuron development GO:0021884 13 5 0,000 0,02302912 0,11126115 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02302912 0,11103818 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02302912 0,1108161 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02302912 0,11059491 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02302912 0,1103746 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02302912 0,11015517 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02302912 0,10993661 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02302912 0,10971891 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02302912 0,10950208 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02302912 0,1092861 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02302912 0,10907097 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02302912 0,10885668 ! basic amino acid transport GO:0015802 11 5 0,000 0,02302912 0,10864324 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02302912 0,10843063 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02302912 0,10821885 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02302912 0,1080079 ! depyrimidination GO:0045008 10 5 0,000 0,02302912 0,10779776 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02302912 0,10758845 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02302912 0,10737994 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02302912 0,10717225 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02302912 0,10696535 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02302912 0,10675925 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02302912 0,10655394 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02302912 0,10634943 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02302912 0,10614569 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02302912 0,10594274 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02302912 0,10574056 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02302912 0,10553914 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02302912 0,1053385 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02302912 0,10513862 ! response to arsenic GO:0046685 10 5 0,000 0,02302912 0,10493949 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02302912 0,10474112 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02302912 0,10454349 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02302912 0,10434661 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02302912 0,10415047 ! response to cadmium ion GO:0046686 7 5 0,000 0,02302912 0,10395507 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02302912 0,1037604 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02302912 0,10356645 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02302912 0,10337323 ! decidualization GO:0046697 11 5 0,000 0,02302912 0,10318073 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02302912 0,10298894 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02302912 0,10279787 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02302912 0,1026075 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02302912 0,10241784 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02302912 0,10222888 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02302912 0,10204061 ! neural tube patterning GO:0021532 7 5 0,000 0,02302912 0,10185304 ! embryonic cleavage GO:0040016 6 5 0,000 0,02302912 0,10166615 ! peroxisome fission GO:0016559 5 5 0,000 0,02302912 0,10147995 ! histone demethylation GO:0016577 10 5 0,000 0,02302912 0,10129443 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02302912 0,10110958 ! mitotic recombination GO:0006312 9 5 0,000 0,02302912 0,10092541 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02302912 0,10074191 ! metaphase plate congression GO:0051310 7 5 0,000 0,02302912 0,10055908 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02302912 0,1003769 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02302912 0,10019539 ! enteric nervous system development GO:0048484 8 5 0,000 0,02302912 0,10001453 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02302912 0,09983433 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02302912 0,09965477 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02302912 0,09947585 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02302912 0,09929758 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02302912 0,09911995 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02302912 0,09894295 ! plasminogen activation GO:0031639 5 5 0,000 0,02302912 0,09876658 ! B cell homeostasis GO:0001782 13 5 0,000 0,02302912 0,09859084 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02302912 0,09841572 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02302912 0,09824123 ! metaphase GO:0051323 8 5 0,000 0,02302912 0,09806735 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02302912 0,09789408 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02302912 0,09772143 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02302912 0,09754939 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02302912 0,09737795 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02302912 0,09720711 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02302912 0,09703687 ! response to redox state GO:0051775 5 5 0,000 0,02302912 0,09686722 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02302912 0,09669817 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02302912 0,09652971 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02302912 0,09636183 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02302912 0,09619453 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02302912 0,09602782 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02302912 0,09586168 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02302912 0,09569612 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02302912 0,09553112 ! striatum development GO:0021756 9 5 0,000 0,02302912 0,0953667 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02302912 0,09520284 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02302912 0,09503954 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02302912 0,0948768 ! glial cell migration GO:0008347 11 5 0,000 0,02302912 0,09471462 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02302912 0,09455299 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02302912 0,09439191 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02302912 0,09423138 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02302912 0,09407139 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02302912 0,09391195 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02302912 0,09375305 ! neuroprotection GO:0043526 6 5 0,000 0,02302912 0,09359468 ! neural plate development GO:0001840 8 5 0,000 0,02302912 0,09343685 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02302912 0,09327955 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02302912 0,09312277 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02302912 0,09296653 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02302912 0,09281081 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02302912 0,0926556 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02302912 0,09250092 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02302912 0,09234675 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02302912 0,0921931 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02302912 0,09203995 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02302912 0,09188732 ! spindle assembly GO:0051225 6 5 0,000 0,02302912 0,09173518 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02302912 0,09158356 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02302912 0,09143243 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02302912 0,0912818 ! drug metabolic process GO:0017144 6 5 0,000 0,02302912 0,09113166 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02302912 0,09098202 ! organ regeneration GO:0031100 7 5 0,000 0,02302912 0,09083287 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02302912 0,09068421 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02302912 0,09053603 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02302912 0,09038834 ! positive regulation of binding GO:0051099 78 51 1,000 0,02357768 0,09239071 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,02357768 0,09224048 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02357768 0,09209074 ! membrane fusion GO:0006944 110 52 1,000 0,02444721 0,09533225 ! synapse organization GO:0050808 85 52 1,000 0,02444721 0,09517799 ! RNA catabolic process GO:0006401 93 53 1,000 0,02532973 0,0984545 ! cell maturation GO:0048469 100 53 1,000 0,02532973 0,0982957 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02532973 0,09813741 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02622509 0,10144303 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02713315 0,10478711 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02757135 0,10630878 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02757135 0,10613869 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02757135 0,10596914 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02757135 0,10580013 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02757135 0,10563166 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02757135 0,10546372 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02757135 0,10529632 ! sleep GO:0030431 13 6 0,000 0,02757135 0,10512945 ! response to oxygen radical GO:0000305 11 6 0,000 0,02757135 0,1049631 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02757135 0,10479728 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02757135 0,10463199 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02757135 0,10446721 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02757135 0,10430296 ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02757135 0,10413922 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02757135 0,10397599 ! forebrain regionalization GO:0021871 8 6 0,000 0,02757135 0,10381327 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02757135 0,10365106 ! male meiosis GO:0007140 7 6 0,000 0,02757135 0,10348936 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02757135 0,10332816 ! response to zinc ion GO:0010043 9 6 0,000 0,02757135 0,10316746 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02757135 0,10300727 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02757135 0,10284757 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02757135 0,10268836 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02757135 0,10252964 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02757135 0,10237142 ! malate metabolic process GO:0006108 11 6 0,000 0,02757135 0,10221368 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02757135 0,10205643 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02757135 0,10189966 ! protein refolding GO:0042026 15 6 0,000 0,02757135 0,10174337 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02757135 0,10158757 ! opsonization GO:0008228 8 6 0,000 0,02757135 0,10143223 ! mating behavior GO:0007617 7 6 0,000 0,02757135 0,10127737 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02757135 0,10112299 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02757135 0,10096907 ! equilibrioception GO:0050957 14 6 0,000 0,02757135 0,10081562 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02757135 0,10066264 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02757135 0,10051012 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02757135 0,10035806 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02757135 0,10020647 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02757135 0,10005532 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02757135 0,09990464 ! toxin metabolic process GO:0009404 11 6 0,000 0,02757135 0,09975441 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02757135 0,09960462 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02757135 0,09945529 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02757135 0,09930641 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02757135 0,09915797 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02757135 0,09900997 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02757135 0,09886241 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02757135 0,0987153 ! thymic T cell selection GO:0045061 12 6 0,000 0,02757135 0,09856862 ! protein lipoylation GO:0009249 10 6 0,000 0,02757135 0,09842237 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02757135 0,09827656 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02757135 0,09813118 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02757135 0,09798623 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02757135 0,09784171 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02757135 0,09769761 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02757135 0,09755394 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02757135 0,09741069 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02757135 0,09726786 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02757135 0,09712545 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02757135 0,09698345 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02757135 0,09684187 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02757135 0,0967007 ! urea metabolic process GO:0019627 7 6 0,000 0,02757135 0,09655994 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02757135 0,09641959 ! neutrophil activation GO:0042119 8 6 0,000 0,02757135 0,09627965 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02757135 0,09614012 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02757135 0,09600098 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02757135 0,09586225 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02757135 0,09572392 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02757135 0,09558599 ! neuron apoptosis GO:0051402 9 6 0,000 0,02757135 0,09544846 ! nucleoside salvage GO:0043174 9 6 0,000 0,02757135 0,09531132 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02757135 0,09517458 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02757135 0,09503822 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02757135 0,09490226 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02757135 0,09476669 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02757135 0,0946315 ! carnitine transport GO:0015879 10 6 0,000 0,02757135 0,0944967 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02757135 0,09436228 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02757135 0,09422824 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02757135 0,09409458 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02757135 0,0939613 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02757135 0,0938284 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02757135 0,09369588 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02757135 0,09356372 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02757135 0,09343194 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02757135 0,09330053 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02757135 0,09316949 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02757135 0,09303882 ! monocyte differentiation GO:0030224 12 6 0,000 0,02757135 0,09290852 ! neural nucleus development GO:0048857 14 6 0,000 0,02757135 0,09277857 ! response to UV-C GO:0010225 11 6 0,000 0,02757135 0,09264899 ! astrocyte development GO:0014002 15 6 0,000 0,02757135 0,09251978 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02757135 0,09239092 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02757135 0,09226242 ! interaction with symbiont GO:0051702 13 6 0,000 0,02757135 0,09213428 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02757135 0,09200649 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02757135 0,09187906 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02757135 0,09175198 ! response to copper ion GO:0046688 10 6 0,000 0,02757135 0,09162525 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02757135 0,09149887 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02757135 0,09137284 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02757135 0,09124715 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02757135 0,09112181 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02757135 0,09099682 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02757135 0,09087216 ! hair follicle maturation GO:0048820 7 6 0,000 0,02757135 0,09074785 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02757135 0,09062388 ! Schwann cell development GO:0014044 15 6 0,000 0,02757135 0,09050025 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02757135 0,09037695 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02757135 0,09025399 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02757135 0,09013136 ! subpallium development GO:0021544 10 6 0,000 0,02757135 0,09000906 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02757135 0,0898871 ! histone ubiquitination GO:0016574 8 6 0,000 0,02757135 0,08976547 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02757135 0,08964416 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02757135 0,08952318 ! G2 phase GO:0051319 16 6 0,000 0,02757135 0,08940253 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02757135 0,08928221 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02757135 0,0891622 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02757135 0,08904252 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02757135 0,08892316 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02757135 0,08880412 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02757135 0,0886854 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02757135 0,088567 ! receptor internalization GO:0031623 10 6 0,000 0,02757135 0,08844891 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02757135 0,08833113 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02757135 0,08821367 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02757135 0,08809652 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02757135 0,08797968 ! protein deubiquitination GO:0016579 14 6 0,000 0,02757135 0,08786315 ! protein destabilization GO:0031648 9 6 0,000 0,02757135 0,08774693 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02757135 0,08763102 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02757135 0,08751541 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02757135 0,08740011 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02757135 0,08728511 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02757135 0,08717041 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02757135 0,08705601 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02757135 0,08694191 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02757135 0,08682812 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02757135 0,08671461 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02757135 0,08660141 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02757135 0,0864885 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02757135 0,08637589 ! catecholamine transport GO:0051937 9 6 0,000 0,02757135 0,08626356 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02757135 0,08615153 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02757135 0,08603979 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02757135 0,08592834 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02757135 0,08581718 ! maternal placenta development GO:0001893 12 6 0,000 0,02757135 0,0857063 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02757135 0,08559572 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02757135 0,08548541 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02757135 0,08537539 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02757135 0,08526566 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02757135 0,0851562 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02757135 0,08504703 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02805379 0,08642435 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02805379 0,08631384 ! muscle fiber development GO:0048747 112 57 1,000 0,02898686 0,08907074 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,02898686 0,08895713 ! lipid modification GO:0030258 97 57 1,000 0,02898686 0,08884381 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02898686 0,08873077 ! maintenance of location GO:0051235 118 57 1,000 0,02898686 0,08861803 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,03185936 0,09727615 ! kidney development GO:0001822 122 60 1,000 0,03185936 0,09715286 ! tRNA transcription GO:0009304 14 7 0,000 0,03209263 0,09774033 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03209263 0,09761676 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03209263 0,09749351 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03209263 0,09737057 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03209263 0,09724793 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03209263 0,09712561 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03209263 0,09700359 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03209263 0,09688188 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03209263 0,09676048 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03209263 0,09663937 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03209263 0,09651857 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03209263 0,09639808 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03209263 0,09627788 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03209263 0,09615798 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03209263 0,09603838 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03209263 0,09591908 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03209263 0,09580007 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03209263 0,09568136 ! glycolipid transport GO:0046836 10 7 0,000 0,03209263 0,09556294 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03209263 0,09544482 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03209263 0,09532699 ! neuron adhesion GO:0007158 12 7 0,000 0,03209263 0,09520944 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03209263 0,09509219 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03209263 0,09497523 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03209263 0,09485855 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03209263 0,09474216 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03209263 0,09462605 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03209263 0,09451023 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03209263 0,09439469 ! mRNA stabilization GO:0048255 18 7 0,000 0,03209263 0,09427944 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03209263 0,09416446 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03209263 0,09404977 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03209263 0,09393535 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03209263 0,09382121 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03209263 0,09370735 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03209263 0,09359377 ! lipoprotein transport GO:0042953 14 7 0,000 0,03209263 0,09348046 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03209263 0,09336742 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03209263 0,09325466 ! rhythmic behavior GO:0007622 15 7 0,000 0,03209263 0,09314217 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03209263 0,09302995 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03209263 0,092918 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03209263 0,09280632 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03209263 0,09269491 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03209263 0,09258376 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03209263 0,09247289 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03209263 0,09236227 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03209263 0,09225192 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03209263 0,09214184 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03209263 0,09203201 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03209263 0,09192245 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03209263 0,09181315 ! spinal cord patterning GO:0021511 13 7 0,000 0,03209263 0,09170411 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03209263 0,09159533 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03209263 0,0914868 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03209263 0,09137853 ! adrenal gland development GO:0030325 17 7 0,000 0,03209263 0,09127052 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03209263 0,09116276 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03209263 0,09105526 ! ovulation GO:0030728 9 7 0,000 0,03209263 0,09094801 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03209263 0,09084101 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03209263 0,09073427 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03209263 0,09062777 ! microtubule nucleation GO:0007020 20 7 0,000 0,03209263 0,09052152 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03209263 0,09041553 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03209263 0,09030978 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03209263 0,09020428 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03209263 0,09009902 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03209263 0,08999401 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03209263 0,08988924 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03209263 0,08978472 ! galactose metabolic process GO:0006012 13 7 0,000 0,03209263 0,08968044 ! vesicle fusion GO:0006906 17 7 0,000 0,03209263 0,0895764 ! response to dietary excess GO:0002021 8 7 0,000 0,03209263 0,08947261 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03209263 0,08936905 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03209263 0,08926573 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03209263 0,08916266 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03209263 0,08905981 ! organ growth GO:0035265 15 7 0,000 0,03209263 0,08895721 ! purine salvage GO:0043101 10 7 0,000 0,03209263 0,08885484 ! nucleoside transport GO:0015858 8 7 0,000 0,03209263 0,08875271 ! parturition GO:0007567 14 7 0,000 0,03209263 0,08865081 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03209263 0,08854915 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03209263 0,08844772 ! spindle checkpoint GO:0031577 15 7 0,000 0,03209263 0,08834652 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03209263 0,08824555 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03209263 0,08814482 ! macrophage differentiation GO:0030225 11 7 0,000 0,03209263 0,08804431 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03209263 0,08794403 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03209263 0,08784398 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03209263 0,08774416 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03209263 0,08764456 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03209263 0,08754519 ! fibrinolysis GO:0042730 10 7 0,000 0,03209263 0,08744605 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03209263 0,08734713 ! eating behavior GO:0042755 7 7 0,000 0,03209263 0,08724843 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03209263 0,08714995 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03209263 0,0870517 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03209263 0,08695367 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03209263 0,08685586 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03209263 0,08675827 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03209263 0,0866609 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03209263 0,08656374 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03209263 0,08646681 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03209263 0,08637009 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03209263 0,08627359 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03209263 0,0861773 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03209263 0,08608123 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03209263 0,08598537 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03209263 0,08588972 ! regulation of meiosis GO:0040020 12 7 0,000 0,03209263 0,08579429 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03209263 0,08569907 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03209263 0,08560406 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03209263 0,08550926 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03209263 0,08541467 ! transcription termination GO:0006353 13 7 0,000 0,03209263 0,08532029 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03209263 0,08522611 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03209263 0,08513215 ! anaphase GO:0051322 17 7 0,000 0,03209263 0,08503839 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03209263 0,08494484 ! axonal fasciculation GO:0007413 18 7 0,000 0,03209263 0,08485149 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03209263 0,08475835 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03209263 0,08466542 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03209263 0,08457268 ! diuresis GO:0030146 12 7 0,000 0,03209263 0,08448015 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03209263 0,08438782 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03209263 0,0842957 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03209263 0,08420377 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03209263 0,08411205 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03209263 0,08402052 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03209263 0,0839292 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03209263 0,08383807 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03209263 0,08374714 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03209263 0,0836564 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03209263 0,08356587 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03209263 0,08347552 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03209263 0,08338538 ! lymph node development GO:0048535 10 7 0,000 0,03209263 0,08329543 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03209263 0,08320567 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03209263 0,0831161 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03209263 0,08302673 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03209263 0,08293755 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03209263 0,08284856 ! adult feeding behavior GO:0008343 9 7 0,000 0,03209263 0,08275976 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03209263 0,08267116 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03209263 0,08258274 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03209263 0,08249451 ! muscle adaptation GO:0043500 14 7 0,000 0,03209263 0,08240647 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03209263 0,08231861 ! retina homeostasis GO:0001895 12 7 0,000 0,03209263 0,08223095 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03209263 0,08214347 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03209263 0,08205617 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03209263 0,08196907 ! protein prenylation GO:0018342 18 7 0,000 0,03209263 0,08188214 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03209263 0,0817954 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03209263 0,08170885 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03209263 0,08162247 ! mesoderm development GO:0007498 119 61 1,000 0,03284084 0,08343724 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0338341 0,0858701 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,03483901 0,08832736 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,03483901 0,08823439 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,03483901 0,08814161 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,03585544 0,09061785 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 1,000 0,03585544 0,09052277 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03659303 0,09228807 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03659303 0,09219144 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03659303 0,092095 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03659303 0,09199877 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03659303 0,09190274 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03659303 0,0918069 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03659303 0,09171127 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03659303 0,09161584 ! meiotic prophase I GO:0007128 13 8 0,000 0,03659303 0,0915206 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03659303 0,09142557 ! oligopeptide transport GO:0006857 15 8 0,000 0,03659303 0,09133073 ! UTP metabolic process GO:0046051 8 8 0,000 0,03659303 0,09123608 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03659303 0,09114164 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03659303 0,09104738 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03659303 0,09095333 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03659303 0,09085946 ! succinate metabolic process GO:0006105 14 8 0,000 0,03659303 0,09076579 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03659303 0,09067232 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03659303 0,09057903 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03659303 0,09048594 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03659303 0,09039304 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03659303 0,09030033 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03659303 0,09020781 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03659303 0,09011548 ! reflex GO:0060004 16 8 0,000 0,03659303 0,09002333 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03659303 0,08993138 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03659303 0,08983961 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03659303 0,08974803 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03659303 0,08965664 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03659303 0,08956543 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03659303 0,08947441 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03659303 0,08938357 ! pigment granule organization GO:0048753 16 8 0,000 0,03659303 0,08929292 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03659303 0,08920245 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03659303 0,08911217 ! histidine metabolic process GO:0006547 16 8 0,000 0,03659303 0,08902206 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03659303 0,08893214 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03659303 0,0888424 ! glycine catabolic process GO:0006546 13 8 0,000 0,03659303 0,08875284 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03659303 0,08866347 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03659303 0,08857427 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03659303 0,08848525 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03659303 0,08839641 ! melanin metabolic process GO:0006582 15 8 0,000 0,03659303 0,08830774 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03659303 0,08821926 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03659303 0,08813095 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03659303 0,08804282 ! macrophage activation GO:0042116 12 8 0,000 0,03659303 0,08795487 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03659303 0,08786709 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03659303 0,08777948 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03659303 0,08769205 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03659303 0,0876048 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03659303 0,08751771 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03659303 0,08743081 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03659303 0,08734407 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03659303 0,0872575 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03659303 0,08717111 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03659303 0,08708489 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03659303 0,08699883 ! response to UV-B GO:0010224 16 8 0,000 0,03659303 0,08691295 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03659303 0,08682724 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03659303 0,0867417 ! intermediate filament organization GO:0045109 12 8 0,000 0,03659303 0,08665632 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03659303 0,08657111 ! cellular extravasation GO:0045123 12 8 0,000 0,03659303 0,08648607 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03659303 0,0864012 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03659303 0,08631649 ! response to antibiotic GO:0046677 11 8 0,000 0,03659303 0,08623195 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03659303 0,08614757 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03659303 0,08606336 ! DNA topological change GO:0006265 12 8 0,000 0,03659303 0,08597932 ! response to tropane GO:0014073 15 8 0,000 0,03659303 0,08589544 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03659303 0,08581172 ! melanosome transport GO:0032402 13 8 0,000 0,03659303 0,08572816 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03659303 0,08564477 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03659303 0,08556154 ! mast cell activation GO:0045576 14 8 0,000 0,03659303 0,08547847 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03659303 0,08539556 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03659303 0,08531281 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03659303 0,08523022 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03659303 0,0851478 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03659303 0,08506553 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03659303 0,08498342 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03659303 0,08490147 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03659303 0,08481967 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03659303 0,08473804 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03659303 0,08465656 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03659303 0,08457524 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03659303 0,08449407 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03659303 0,08441306 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03659303 0,0843322 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03659303 0,0842515 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03659303 0,08417096 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03659303 0,08409056 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03659303 0,08401033 ! hormone catabolic process GO:0042447 17 8 0,000 0,03659303 0,08393024 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03659303 0,08385031 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03659303 0,08377052 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03659303 0,08369089 ! ATP catabolic process GO:0006200 11 8 0,000 0,03659303 0,08361142 ! blastocyst growth GO:0001832 19 8 0,000 0,03659303 0,08353209 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03659303 0,08345291 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03659303 0,08337388 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03659303 0,08329501 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03659303 0,08321628 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03659303 0,0831377 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03659303 0,08305927 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03659303 0,08298098 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03659303 0,08290284 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03659303 0,08282486 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03659303 0,08274701 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03659303 0,08266932 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03659303 0,08259176 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03659303 0,08251436 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03659303 0,0824371 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03659303 0,08235998 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03659303 0,08228301 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03659303 0,08220618 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,03688327 0,08278091 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,03792235 0,08503372 ! developmental maturation GO:0021700 116 66 1,000 0,03792235 0,08495455 ! activation of MAPK activity GO:0000187 115 67 1,000 0,03897258 0,08722608 ! lung development GO:0030324 144 67 1,000 0,03897258 0,08714501 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,03897258 0,0870641 ! adaptive immune response GO:0002250 119 67 1,000 0,03897258 0,08698333 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,04003383 0,08926913 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,04003383 0,08918647 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,04003383 0,08910397 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04107265 0,0913316 ! axon extension GO:0048675 15 9 0,000 0,04107265 0,09124727 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04107265 0,09116309 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04107265 0,09107907 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04107265 0,09099521 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04107265 0,09091149 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04107265 0,09082794 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04107265 0,09074453 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04107265 0,09066128 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04107265 0,09057818 ! phosphate transport GO:0006817 19 9 0,000 0,04107265 0,09049523 ! reproductive behavior GO:0019098 19 9 0,000 0,04107265 0,09041244 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04107265 0,09032979 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04107265 0,0902473 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04107265 0,09016496 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04107265 0,09008277 ! GTP metabolic process GO:0046039 9 9 0,000 0,04107265 0,09000072 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04107265 0,08991883 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04107265 0,08983709 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04107265 0,08975549 ! artery development GO:0060840 24 9 0,000 0,04107265 0,08967404 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04107265 0,08959274 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04107265 0,08951159 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04107265 0,08943058 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04107265 0,08934972 ! chemosensory behavior GO:0007635 20 9 0,000 0,04107265 0,08926901 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04107265 0,08918844 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04107265 0,08910802 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04107265 0,08902774 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04107265 0,08894761 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04107265 0,08886762 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04107265 0,08878778 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04107265 0,08870807 ! protein targeting to ER GO:0045047 22 9 0,000 0,04107265 0,08862852 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04107265 0,0885491 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04107265 0,08846983 ! T cell selection GO:0045058 23 9 0,000 0,04107265 0,08839069 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04107265 0,0883117 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04107265 0,08823285 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04107265 0,08815414 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04107265 0,08807557 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04107265 0,08799715 ! mannose metabolic process GO:0006013 13 9 0,000 0,04107265 0,08791886 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04107265 0,08784071 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04107265 0,08776269 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04107265 0,08768482 ! receptor clustering GO:0043113 18 9 0,000 0,04107265 0,08760709 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04107265 0,08752949 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04107265 0,08745203 ! ruffle organization GO:0031529 15 9 0,000 0,04107265 0,08737471 ! retinol metabolic process GO:0042572 18 9 0,000 0,04107265 0,08729752 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04107265 0,08722047 ! behavioral fear response GO:0001662 22 9 0,000 0,04107265 0,08714356 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04107265 0,08706678 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04107265 0,08699014 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04107265 0,08691363 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04107265 0,08683725 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04107265 0,08676101 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04107265 0,08668491 ! segment specification GO:0007379 13 9 0,000 0,04107265 0,08660893 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04107265 0,0865331 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04107265 0,08645739 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04107265 0,08638181 ! response to amine stimulus GO:0014075 13 9 0,000 0,04107265 0,08630637 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04107265 0,08623106 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04107265 0,08615588 ! erythrocyte development GO:0048821 15 9 0,000 0,04107265 0,08608083 ! gas homeostasis GO:0033483 16 9 0,000 0,04107265 0,08600591 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04107265 0,08593113 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04107265 0,08585647 ! renal water homeostasis GO:0003091 14 9 0,000 0,04107265 0,08578194 ! postreplication repair GO:0006301 22 9 0,000 0,04107265 0,08570754 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04107265 0,08563327 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04107265 0,08555913 ! icosanoid secretion GO:0032309 15 9 0,000 0,04107265 0,08548512 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04107265 0,08541123 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04107265 0,08533747 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04107265 0,08526384 ! regulation of cell division GO:0051302 15 9 0,000 0,04107265 0,08519034 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04107265 0,08511696 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04107265 0,08504371 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04107265 0,08497059 ! sterol catabolic process GO:0016127 11 9 0,000 0,04107265 0,08489759 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04107265 0,08482472 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04107265 0,08475197 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04107265 0,08467934 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04107265 0,08460684 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04107265 0,08453447 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04107265 0,08446222 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04107265 0,08439009 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04107265 0,08431808 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04107265 0,0842462 ! purine base metabolic process GO:0006144 21 9 0,000 0,04107265 0,08417444 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04107265 0,0841028 ! pigment granule transport GO:0051904 17 9 0,000 0,04107265 0,08403129 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04107265 0,08395989 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04107265 0,08388862 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04107265 0,08381747 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04107265 0,08374644 ! mitochondrion localization GO:0051646 15 9 0,000 0,04107265 0,08367552 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,04110597 0,08367255 ! respiratory tube development GO:0030323 150 70 1,000 0,04218888 0,08580426 ! reproductive structure development GO:0048608 113 71 1,000 0,04328243 0,087954 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04438652 0,09012149 ! carbohydrate transport GO:0008643 110 72 1,000 0,04438652 0,0900455 ! respiratory system development GO:0060541 153 72 1,000 0,04438652 0,08996964 ! axon guidance GO:0007411 139 73 1,000 0,04550101 0,09215104 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04553159 0,09213542 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04553159 0,09205799 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04553159 0,0919807 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04553159 0,09190353 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04553159 0,0918265 ! synapsis GO:0007129 13 10 0,000 0,04553159 0,09174959 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04553159 0,09167281 ! N-glycan processing GO:0006491 20 10 0,000 0,04553159 0,09159616 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04553159 0,09151964 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04553159 0,09144325 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04553159 0,09136698 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04553159 0,09129084 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04553159 0,09121483 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04553159 0,09113894 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04553159 0,09106318 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04553159 0,09098755 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04553159 0,09091204 ! androgen metabolic process GO:0008209 17 10 0,000 0,04553159 0,09083666 ! phospholipid efflux GO:0033700 16 10 0,000 0,04553159 0,0907614 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04553159 0,09068627 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04553159 0,09061126 ! pathogenesis GO:0009405 13 10 0,000 0,04553159 0,09053637 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04553159 0,09046161 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04553159 0,09038697 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04553159 0,09031246 ! endoderm development GO:0007492 16 10 0,000 0,04553159 0,09023806 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04553159 0,09016379 ! arginine catabolic process GO:0006527 13 10 0,000 0,04553159 0,09008965 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04553159 0,09001562 ! proline metabolic process GO:0006560 13 10 0,000 0,04553159 0,08994172 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04553159 0,08986793 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04553159 0,08979427 ! V(D)J recombination GO:0033151 28 10 0,000 0,04553159 0,08972073 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04553159 0,08964731 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04553159 0,08957401 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04553159 0,08950082 ! B cell proliferation GO:0042100 18 10 0,000 0,04553159 0,08942776 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04553159 0,08935482 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04553159 0,089282 ! multicellular organism growth GO:0035264 18 10 0,000 0,04553159 0,08920929 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04553159 0,0891367 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04553159 0,08906424 ! epithelial cell development GO:0002064 20 10 0,000 0,04553159 0,08899188 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04553159 0,08891965 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04553159 0,08884753 ! macroautophagy GO:0016236 17 10 0,000 0,04553159 0,08877553 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04553159 0,08870365 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04553159 0,08863188 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04553159 0,08856023 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04553159 0,0884887 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04553159 0,08841728 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04553159 0,08834598 ! brain morphogenesis GO:0048854 23 10 0,000 0,04553159 0,08827479 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04553159 0,08820371 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04553159 0,08813275 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04553159 0,0880619 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04553159 0,08799117 ! DNA ligation GO:0006266 19 10 0,000 0,04553159 0,08792055 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04553159 0,08785005 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04553159 0,08777965 ! melanosome localization GO:0032400 16 10 0,000 0,04553159 0,08770937 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04553159 0,08763921 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04553159 0,08756915 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04553159 0,08749921 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04553159 0,08742938 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04553159 0,08735966 ! mRNA cleavage GO:0006379 17 10 0,000 0,04553159 0,08729005 ! protein sumoylation GO:0016925 15 10 0,000 0,04553159 0,08722055 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04553159 0,08715116 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04553159 0,08708188 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04553159 0,08701272 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04553159 0,08694366 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04553159 0,08687471 ! salivary gland development GO:0007431 27 10 0,000 0,04553159 0,08680587 ! prophase GO:0051324 15 10 0,000 0,04553159 0,08673714 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04553159 0,08666852 ! apical protein localization GO:0045176 15 10 0,000 0,04553159 0,08660001 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04553159 0,0865316 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04553159 0,08646331 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04553159 0,08639512 ! midbrain development GO:0030901 13 10 0,000 0,04553159 0,08632704 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04553159 0,08625906 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04553159 0,0861912 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04553159 0,08612343 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04553159 0,08605578 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04553159 0,08598823 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04553159 0,08592079 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04553159 0,08585346 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04553159 0,08578622 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04553159 0,0857191 ! oocyte development GO:0048599 17 10 0,000 0,04553159 0,08565208 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04553159 0,08558516 ! blastocyst formation GO:0001825 17 10 0,000 0,04553159 0,08551835 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04553159 0,08545165 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04553159 0,08538504 ! activation of innate immune response GO:0002218 12 10 0,000 0,04553159 0,08531854 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04553159 0,08525215 ! response to nicotine GO:0035094 20 10 0,000 0,04553159 0,08518585 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04553159 0,08511967 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04553159 0,08505358 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04553159 0,08498759 ! localization within membrane GO:0051668 20 10 0,000 0,04553159 0,08492171 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04776075 0,08901035 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04776075 0,08894145 ! defense response to bacterium GO:0042742 89 76 1,000 0,04890575 0,09100328 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04996995 0,09291166 ! respiratory burst GO:0045730 17 11 0,000 0,04996995 0,09283992 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04996995 0,09276828 ! neuron fate specification GO:0048665 17 11 0,000 0,04996995 0,09269676 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04996995 0,09262534 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04996995 0,09255404 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04996995 0,09248284 ! thyroid gland development GO:0030878 26 11 0,000 0,04996995 0,09241175 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04996995 0,09234078 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04996995 0,09226991 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04996995 0,09219915 ! response to pain GO:0048265 24 11 0,000 0,04996995 0,0921285 ! T cell proliferation GO:0042098 26 11 0,000 0,04996995 0,09205796 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04996995 0,09198752 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04996995 0,0919172 ! bone resorption GO:0045453 16 11 0,000 0,04996995 0,09184698 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,04996995 0,09177687 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04996995 0,09170686 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04996995 0,09163696 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04996995 0,09156717 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04996995 0,09149748 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04996995 0,0914279 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04996995 0,09135843 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04996995 0,09128906 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04996995 0,0912198 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04996995 0,09115064 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04996995 0,09108159 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04996995 0,09101264 ! UV protection GO:0009650 19 11 0,000 0,04996995 0,09094379 ! adult heart development GO:0007512 14 11 0,000 0,04996995 0,09087505 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04996995 0,09080641 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04996995 0,09073788 ! temperature homeostasis GO:0001659 17 11 0,000 0,04996995 0,09066945 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04996995 0,09060113 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04996995 0,0905329 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04996995 0,09046478 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04996995 0,09039676 ! regulation of organ growth GO:0046620 13 11 0,000 0,04996995 0,09032885 ! pigment granule localization GO:0051875 20 11 0,000 0,04996995 0,09026103 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04996995 0,09019332 ! vasoconstriction GO:0042310 18 11 0,000 0,04996995 0,09012571 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04996995 0,0900582 ! embryonic axis specification GO:0000578 18 11 0,000 0,04996995 0,08999079 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04996995 0,08992348 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04996995 0,08985627 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04996995 0,08978917 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04996995 0,08972216 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04996995 0,08965525 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04996995 0,08958845 ! zymogen activation GO:0031638 15 11 0,000 0,04996995 0,08952174 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04996995 0,08945513 ! nucleosome positioning GO:0016584 15 11 0,000 0,04996995 0,08938862 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04996995 0,08932221 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04996995 0,0892559 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04996995 0,08918968 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04996995 0,08912357 ! acid secretion GO:0046717 18 11 0,000 0,04996995 0,08905755 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04996995 0,08899163 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04996995 0,08892581 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04996995 0,08886008 ! oocyte differentiation GO:0009994 18 11 0,000 0,04996995 0,08879446 ! thymus development GO:0048538 27 11 0,000 0,04996995 0,08872892 ! cholesterol efflux GO:0033344 19 11 0,000 0,04996995 0,08866349 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04996995 0,08859815 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04996995 0,08853291 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04996995 0,08846777 ! embryonic gut development GO:0048566 15 11 0,000 0,04996995 0,08840272 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04996995 0,08833776 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04996995 0,0882729 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04996995 0,08820814 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04996995 0,08814347 ! defense response to fungus GO:0050832 13 11 0,000 0,04996995 0,0880789 ! developmental induction GO:0031128 19 11 0,000 0,04996995 0,08801442 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04996995 0,08795003 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04996995 0,08788574 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04996995 0,08782154 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04996995 0,08775744 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04996995 0,08769343 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04996995 0,08762951 ! nucleus localization GO:0051647 19 11 0,000 0,04996995 0,08756569 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04996995 0,08750196 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,05122546 0,08963524 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,05122546 0,0895701 ! protein oligomerization GO:0051259 139 78 1,000 0,05122546 0,08950505 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,05358399 0,09355812 ! response to metal ion GO:0010038 140 80 1,000 0,05358399 0,09349027 ! muscle cell differentiation GO:0042692 159 80 1,000 0,05358399 0,09342252 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05438781 0,0947553 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05438781 0,09468674 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05438781 0,09461827 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05438781 0,09454991 ! virus-host interaction GO:0019048 29 12 0,000 0,05438781 0,09448164 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05438781 0,09441347 ! cartilage condensation GO:0001502 20 12 0,000 0,05438781 0,0943454 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05438781 0,09427743 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05438781 0,09420956 ! protein complex disassembly GO:0043241 27 12 0,000 0,05438781 0,09414178 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05438781 0,0940741 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05438781 0,09400652 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05438781 0,09393903 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05438781 0,09387165 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05438781 0,09380435 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05438781 0,09373716 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05438781 0,09367006 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05438781 0,09360306 ! drug transport GO:0015893 16 12 0,000 0,05438781 0,09353615 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05438781 0,09346934 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05438781 0,09340262 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05438781 0,093336 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05438781 0,09326948 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05438781 0,09320304 ! forebrain cell migration GO:0021885 21 12 0,000 0,05438781 0,09313671 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05438781 0,09307046 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05438781 0,09300432 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05438781 0,09293826 ! entry into host cell GO:0030260 32 12 0,000 0,05438781 0,0928723 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05438781 0,09280644 ! monoamine transport GO:0015844 18 12 0,000 0,05438781 0,09274066 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05438781 0,09267498 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05438781 0,09260939 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05438781 0,0925439 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05438781 0,0924785 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05438781 0,09241319 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05438781 0,09234797 ! protein homotetramerization GO:0051289 21 12 0,000 0,05438781 0,09228284 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05438781 0,09221781 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05438781 0,09215287 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05438781 0,09208802 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05438781 0,09202326 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05438781 0,09195859 ! cranial nerve development GO:0021545 20 12 0,000 0,05438781 0,09189401 ! fucose catabolic process GO:0019317 22 12 0,000 0,05438781 0,09182953 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 26 12 0,000 0,05438781 0,09176513 ! histone methylation GO:0016571 26 12 0,000 0,05438781 0,09170082 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05438781 0,09163661 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05438781 0,09157248 ! gland morphogenesis GO:0022612 29 12 0,000 0,05438781 0,09150844 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05438781 0,0914445 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05438781 0,09138064 ! T cell homeostasis GO:0043029 25 12 0,000 0,05438781 0,09131687 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05438781 0,09125319 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05438781 0,0911896 ! spleen development GO:0048536 22 12 0,000 0,05438781 0,0911261 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05438781 0,09106268 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05438781 0,09099936 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05438781 0,09093612 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05438781 0,09087297 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05438781 0,09080991 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05438781 0,09074693 ! response to cold GO:0009409 17 12 0,000 0,05438781 0,09068404 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05438781 0,09062124 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05438781 0,09055853 ! T cell activation GO:0042110 168 81 1,000 0,05477753 0,09114436 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,05477753 0,09108137 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,05598044 0,09301723 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,05598044 0,09295303 ! regulation of lyase activity GO:0051339 160 83 1,000 0,05719261 0,09490028 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,05841392 0,09686002 ! negative regulation of transport GO:0051051 153 84 1,000 0,05841392 0,09679331 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05878528 0,09734162 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05878528 0,09727467 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05878528 0,09720782 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05878528 0,09714106 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05878528 0,09707438 ! lipid localization GO:0010876 28 13 0,000 0,05878528 0,0970078 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,05878528 0,09694131 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05878528 0,09687492 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05878528 0,09680861 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05878528 0,09674239 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05878528 0,09667627 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05878528 0,09661023 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05878528 0,09654428 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05878528 0,09647843 ! methionine metabolic process GO:0006555 27 13 0,000 0,05878528 0,09641266 ! plasma membrane organization GO:0007009 24 13 0,000 0,05878528 0,09634699 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05878528 0,0962814 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05878528 0,0962159 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05878528 0,09615049 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05878528 0,09608517 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05878528 0,09601994 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05878528 0,0959548 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05878528 0,09588975 ! exocrine system development GO:0035272 32 13 0,000 0,05878528 0,09582478 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05878528 0,0957599 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05878528 0,09569511 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05878528 0,09563041 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05878528 0,09556579 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05878528 0,09550127 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05878528 0,09543683 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05878528 0,09537247 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05878528 0,0953082 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05878528 0,09524402 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05878528 0,09517993 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05878528 0,09511592 ! ribosome assembly GO:0042255 17 13 0,000 0,05878528 0,095052 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05878528 0,09498816 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05878528 0,09492441 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05878528 0,09486075 ! chromatin silencing GO:0006342 26 13 0,000 0,05878528 0,09479717 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05878528 0,09473367 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05878528 0,09467027 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05878528 0,09460694 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05878528 0,0945437 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05878528 0,09448055 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05878528 0,09441747 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05878528 0,09435449 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05878528 0,09429158 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05878528 0,09422876 ! embryonic placenta development GO:0001892 23 13 0,000 0,05878528 0,09416603 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05878528 0,09410338 ! insulin secretion GO:0030073 23 13 0,000 0,05878528 0,09404081 ! actin filament polymerization GO:0030041 24 13 0,000 0,05878528 0,09397832 ! acrosome reaction GO:0007340 18 13 0,000 0,05878528 0,09391592 ! response to unfolded protein GO:0006986 131 85 1,000 0,05964426 0,09522501 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,05964426 0,09516186 ! response to inorganic substance GO:0010035 153 86 1,000 0,06088353 0,09707474 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,06213162 0,09899912 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,06213162 0,0989336 GO:0070201|regulation of establishment of protein localization, ! rRNA transcription GO:0009303 25 14 0,000 0,06316244 0,10050848 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,06316244 0,10044205 ! reproductive cellular process GO:0048610 20 14 0,000 0,06316244 0,10037571 ! tRNA modification GO:0006400 20 14 0,000 0,06316244 0,10030946 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06316244 0,10024329 ! regulation of S phase GO:0033261 23 14 0,000 0,06316244 0,10017721 ! water transport GO:0006833 21 14 0,000 0,06316244 0,10011122 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06316244 0,10004531 ! non-recombinational repair GO:0000726 25 14 0,000 0,06316244 0,09997949 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06316244 0,09991376 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06316244 0,09984811 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06316244 0,09978255 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06316244 0,09971708 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06316244 0,09965169 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06316244 0,09958639 ! palate development GO:0060021 31 14 0,000 0,06316244 0,09952117 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06316244 0,09945604 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06316244 0,09939099 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06316244 0,09932603 ! arginine metabolic process GO:0006525 17 14 0,000 0,06316244 0,09926115 ! regulation of heart rate GO:0002027 24 14 0,000 0,06316244 0,09919636 ! organic alcohol transport GO:0015850 29 14 0,000 0,06316244 0,09913165 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06316244 0,09906703 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06316244 0,09900249 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06316244 0,09893804 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06316244 0,09887367 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06316244 0,09880938 ! L-amino acid transport GO:0015807 30 14 0,000 0,06316244 0,09874518 ! bone mineralization GO:0030282 17 14 0,000 0,06316244 0,09868106 ! stem cell development GO:0048864 43 14 0,000 0,06316244 0,09861702 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06316244 0,09855306 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06316244 0,09848919 ! cerebellum development GO:0021549 21 14 0,000 0,06316244 0,09842541 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06316244 0,0983617 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06316244 0,09829808 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06316244 0,09823454 ! cofactor transport GO:0051181 26 14 0,000 0,06316244 0,09817108 ! NADP metabolic process GO:0006739 24 14 0,000 0,06316244 0,0981077 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06316244 0,0980444 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06316244 0,09798119 ! intestinal absorption GO:0050892 25 14 0,000 0,06316244 0,09791806 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06316244 0,09785501 ! oxygen transport GO:0015671 21 14 0,000 0,06316244 0,09779204 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06316244 0,09772915 ! male genitalia development GO:0030539 24 14 0,000 0,06316244 0,09766634 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06316244 0,09760361 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06316244 0,09754097 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,06465382 0,09978005 ! ossification GO:0001503 188 90 1,000 0,06592772 0,10168083 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,06592772 0,1016157 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,06592772 0,10155064 ! sex differentiation GO:0007548 145 90 1,000 0,06592772 0,10148567 ! bone development GO:0060348 189 91 1,000 0,06721002 0,10339341 ! response to protein stimulus GO:0051789 149 91 1,000 0,06721002 0,10332735 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06751939 0,10373668 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06751939 0,10367048 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06751939 0,10360437 ! superoxide anion generation GO:0042554 20 15 0,000 0,06751939 0,10353833 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06751939 0,10347239 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06751939 0,10340652 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06751939 0,10334074 ! copper ion transport GO:0006825 20 15 0,000 0,06751939 0,10327505 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06751939 0,10320943 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06751939 0,1031439 ! sulfate transport GO:0008272 23 15 0,000 0,06751939 0,10307846 ! response to cAMP GO:0051591 22 15 0,000 0,06751939 0,10301309 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06751939 0,10294781 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06751939 0,10288261 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06751939 0,1028175 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06751939 0,10275246 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06751939 0,10268751 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06751939 0,10262265 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06751939 0,10255786 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06751939 0,10249315 ! pituitary gland development GO:0021983 29 15 0,000 0,06751939 0,10242853 ! vesicle coating GO:0006901 33 15 0,000 0,06751939 0,10236399 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06751939 0,10229953 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06751939 0,10223515 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06751939 0,10217085 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06751939 0,10210663 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06751939 0,10204249 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06751939 0,10197844 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06751939 0,10191446 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06751939 0,10185056 ! histone deacetylation GO:0016575 20 15 0,000 0,06751939 0,10178675 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06751939 0,10172301 ! tissue regeneration GO:0042246 26 15 0,000 0,06751939 0,10165935 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06751939 0,10159578 ! water homeostasis GO:0030104 27 15 0,000 0,06751939 0,10153228 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06751939 0,10146886 ! muscle maintenance GO:0046716 26 15 0,000 0,06751939 0,10140552 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06751939 0,10134226 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06751939 0,10127908 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06751939 0,10121598 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06751939 0,10115296 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06751939 0,10109001 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06751939 0,10102714 ! detection of bacterium GO:0016045 18 15 0,000 0,06751939 0,10096435 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06751939 0,10090164 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06751939 0,10083901 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06751939 0,10077646 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06751939 0,10071398 ! peptide hormone processing GO:0016486 23 15 0,000 0,06751939 0,10065158 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06979937 0,10398593 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,06979937 0,10392158 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,06979937 0,10385731 ! regulation of membrane potential GO:0042391 164 93 1,000 0,06979937 0,10379313 ! female pregnancy GO:0007565 164 94 1,000 0,07110622 0,10567113 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07185622 0,10671979 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07185622 0,10665396 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07185622 0,1065882 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07185622 0,10652253 ! bone remodeling GO:0046849 27 16 0,000 0,07185622 0,10645693 ! filopodium assembly GO:0046847 32 16 0,000 0,07185622 0,10639142 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07185622 0,10632599 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07185622 0,10626064 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07185622 0,10619537 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07185622 0,10613018 ! startle response GO:0001964 28 16 0,000 0,07185622 0,10606507 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07185622 0,10600004 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07185622 0,10593509 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07185622 0,10587022 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07185622 0,10580542 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07185622 0,10574071 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07185622 0,10567608 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07185622 0,10561152 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07185622 0,10554705 ! lysosomal transport GO:0007041 26 16 0,000 0,07185622 0,10548265 ! fructose metabolic process GO:0006000 25 16 0,000 0,07185622 0,10541833 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07185622 0,10535409 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07185622 0,10528993 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07185622 0,10522584 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07185622 0,10516184 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07185622 0,10509791 ! axon cargo transport GO:0008088 43 16 0,000 0,07185622 0,10503406 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07185622 0,10497029 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07185622 0,10490659 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07185622 0,10484297 ! DNA replication initiation GO:0006270 27 16 0,000 0,07185622 0,10477943 ! neuron recognition GO:0008038 35 16 0,000 0,07185622 0,10471597 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07185622 0,10465258 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07185622 0,10458927 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07185622 0,10452604 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07185622 0,10446288 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,07185622 0,1043998 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07185622 0,10433679 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07185622 0,10427386 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07185622 0,10421101 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07185622 0,10414823 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07185622 0,10408553 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07185622 0,1040229 ! defense response to virus GO:0051607 37 16 0,000 0,07185622 0,10396035 ! leukocyte differentiation GO:0002521 202 96 1,000 0,07374376 0,1066271 ! mRNA transport GO:0051028 169 96 1,000 0,07374376 0,10656305 ! protein ubiquitination GO:0016567 217 97 1,000 0,07507425 0,10842056 ! regulation of protein localization GO:0032880 176 97 1,000 0,07507425 0,10835552 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07617302 0,10987548 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07617302 0,10980964 ! metencephalon development GO:0022037 30 17 0,000 0,07617302 0,10974389 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07617302 0,10967821 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07617302 0,10961262 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07617302 0,1095471 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07617302 0,10948166 ! signal complex assembly GO:0007172 41 17 0,000 0,07617302 0,10941629 ! endothelial cell migration GO:0043542 28 17 0,000 0,07617302 0,10935101 ! inositol metabolic process GO:0006020 28 17 0,000 0,07617302 0,1092858 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07617302 0,10922068 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07617302 0,10915562 ! glial cell development GO:0021782 27 17 0,000 0,07617302 0,10909065 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07617302 0,10902575 ! adult walking behavior GO:0007628 33 17 0,000 0,07617302 0,10896094 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07617302 0,10889619 ! heart looping GO:0001947 30 17 0,000 0,07617302 0,10883153 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07617302 0,10876694 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07617302 0,10870243 ! myoblast differentiation GO:0045445 45 17 0,000 0,07617302 0,10863799 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07617302 0,10857363 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07617302 0,10850935 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07617302 0,10844514 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07617302 0,10838101 ! glycine metabolic process GO:0006544 28 17 0,000 0,07617302 0,10831696 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,07617302 0,10825298 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07617302 0,10818908 ! NAD metabolic process GO:0019674 29 17 0,000 0,07617302 0,10812525 ! membrane budding GO:0006900 37 17 0,000 0,07617302 0,10806149 ! DNA integration GO:0015074 29 17 0,000 0,07617302 0,10799782 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07617302 0,10793421 ! regulation of protein binding GO:0043393 33 17 0,000 0,07617302 0,10787069 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07617302 0,10780723 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07617302 0,10774385 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07617302 0,10768055 ! genitalia development GO:0048806 30 17 0,000 0,07617302 0,10761732 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07617302 0,10755416 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07617302 0,10749108 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07617302 0,10742807 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07617302 0,10736514 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07617302 0,10730228 ! steroid catabolic process GO:0006706 31 17 0,000 0,07617302 0,10723949 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07617302 0,10717678 ! gas transport GO:0015669 25 17 0,000 0,07617302 0,10711414 ! organic cation transport GO:0015695 31 17 0,000 0,07617302 0,10705157 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07617302 0,10698908 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07617302 0,10692666 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07617302 0,10686431 ! microspike assembly GO:0030035 36 17 0,000 0,07617302 0,10680204 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07617302 0,10673983 ! response to virus GO:0009615 160 98 1,000 0,07641242 0,10701297 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,07775817 0,1088343 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,07775817 0,10877102 GO:0060538|skeletal muscle organ development, ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08046989 0,11249887 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08046989 0,11243354 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08046989 0,11236829 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08046989 0,11230311 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08046989 0,11223801 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08046989 0,11217298 ! memory GO:0007613 31 18 0,000 0,08046989 0,11210803 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08046989 0,11204315 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08046989 0,11197835 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08046989 0,11191362 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08046989 0,11184897 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08046989 0,11178439 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08046989 0,11171989 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08046989 0,11165546 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08046989 0,1115911 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08046989 0,11152682 ! response to fungus GO:0009620 21 18 0,000 0,08046989 0,11146261 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08046989 0,11139848 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08046989 0,11133442 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08046989 0,11127044 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08046989 0,11120653 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08046989 0,11114269 ! vitamin transport GO:0051180 27 18 0,000 0,08046989 0,11107892 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08046989 0,11101523 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08046989 0,11095161 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08046989 0,11088807 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08046989 0,11082459 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08046989 0,11076119 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08046989 0,11069786 ! nerve development GO:0021675 28 18 0,000 0,08046989 0,11063461 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08046989 0,11057142 ! protein secretion GO:0009306 39 19 0,000 0,08474692 0,1163819 ! positive regulation of translation GO:0045727 30 19 0,000 0,08474692 0,11631551 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08474692 0,11624919 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08474692 0,11618296 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08474692 0,11611679 ! skin development GO:0043588 36 19 0,000 0,08474692 0,1160507 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08474692 0,11598469 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08474692 0,11591875 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08474692 0,11585289 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08474692 0,1157871 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08474692 0,11572139 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08474692 0,11565575 ! cerebral cortex development GO:0021987 36 19 0,000 0,08474692 0,11559019 ! pigmentation during development GO:0048066 41 19 0,000 0,08474692 0,1155247 ! heme metabolic process GO:0042168 36 19 0,000 0,08474692 0,11545928 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08474692 0,11539394 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08474692 0,11532867 ! peptide cross-linking GO:0018149 37 19 0,000 0,08474692 0,11526348 ! protein export from nucleus GO:0006611 36 19 0,000 0,08474692 0,11519835 ! heart process GO:0003015 30 19 0,000 0,08474692 0,11513331 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08474692 0,11506833 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08474692 0,11500343 ! visual learning GO:0008542 36 19 0,000 0,08474692 0,11493861 ! cellular pigmentation GO:0033059 36 19 0,000 0,08474692 0,11487385 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08474692 0,11480917 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08474692 0,11474456 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08474692 0,11468003 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08474692 0,11461556 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08474692 0,11455117 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08474692 0,11448685 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08474692 0,11442261 ! cilium assembly GO:0042384 37 19 0,000 0,08474692 0,11435843 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08474692 0,11429433 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08900419 0,11996868 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08900419 0,11990151 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08900419 0,11983441 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08900419 0,11976739 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08900419 0,11970044 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,08900419 0,11963357 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,08900419 0,11956677 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08900419 0,11950005 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08900419 0,1194334 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08900419 0,11936683 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08900419 0,11930033 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08900419 0,1192339 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08900419 0,11916755 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08900419 0,11910127 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08900419 0,11903507 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,08900419 0,11896894 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08900419 0,11890288 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08900419 0,1188369 ! body fluid secretion GO:0007589 31 20 0,000 0,08900419 0,11877099 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08900419 0,11870515 ! peptide secretion GO:0002790 35 20 0,000 0,08900419 0,11863938 ! stem cell differentiation GO:0048863 53 20 0,000 0,08900419 0,11857369 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08900419 0,11850807 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08900419 0,11844253 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08900419 0,11837705 ! sensory perception of pain GO:0019233 30 20 0,000 0,08900419 0,11831165 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08900419 0,11824632 ! diencephalon development GO:0021536 34 20 0,000 0,08900419 0,11818106 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08900419 0,11811588 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08900419 0,11805077 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08900419 0,11798572 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08900419 0,11792075 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08900419 0,11785586 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08900419 0,11779103 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08900419 0,11772627 ! regulation of glucose import GO:0046324 29 20 0,000 0,08900419 0,11766159 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08900419 0,11759697 ! actin filament-based movement GO:0030048 43 20 0,000 0,08900419 0,11753243 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08900419 0,11746796 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08900419 0,11740356 ! regulation of cell killing GO:0031341 42 21 0,000 0,09324181 0,12292591 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09324181 0,12285859 ! hormone secretion GO:0046879 38 21 0,000 0,09324181 0,12279134 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09324181 0,12272417 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09324181 0,12265707 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,09324181 0,12259005 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09324181 0,12252309 ! ovarian follicle development GO:0001541 35 21 0,000 0,09324181 0,12245621 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,09324181 0,12238941 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09324181 0,12232267 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09324181 0,12225601 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09324181 0,12218942 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09324181 0,12212291 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09324181 0,12205647 ! cytolysis GO:0019835 24 21 0,000 0,09324181 0,12199009 ! vasodilation GO:0042311 39 21 0,000 0,09324181 0,1219238 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09324181 0,12185757 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09324181 0,12179141 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09324181 0,12172533 ! oogenesis GO:0048477 36 21 0,000 0,09324181 0,12165932 ! DNA modification GO:0006304 34 21 0,000 0,09324181 0,12159338 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,09324181 0,12152751 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,09324181 0,12146171 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09324181 0,12139599 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09324181 0,12133033 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09324181 0,12126475 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09324181 0,12119923 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09324181 0,12113379 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09324181 0,12106842 ! collagen catabolic process GO:0030574 28 21 0,000 0,09324181 0,12100312 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09324181 0,12093789 ! gut development GO:0048565 39 21 0,000 0,09324181 0,12087273 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09745985 0,12627269 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09745985 0,12620473 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09745985 0,12613684 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09745985 0,12606903 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09745985 0,12600128 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09745985 0,12593361 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09745985 0,12586602 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09745985 0,12579849 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09745985 0,12573104 ! regeneration GO:0031099 41 22 0,000 0,09745985 0,12566366 ! keratinization GO:0031424 28 22 0,000 0,09745985 0,12559635 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09745985 0,12552912 ! sensory perception of taste GO:0050909 28 22 0,000 0,09745985 0,12546195 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09745985 0,12539486 ! vacuolar transport GO:0007034 36 22 0,000 0,09745985 0,12532784 ! lysosome organization GO:0007040 41 22 0,000 0,09745985 0,12526089 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09745985 0,12519401 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09745985 0,12512721 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09745985 0,12506047 ! fucose metabolic process GO:0006004 39 22 0,000 0,09745985 0,12499381 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09745985 0,12492722 ! ureteric bud development GO:0001657 43 22 0,000 0,09745985 0,1248607 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09745985 0,12479425 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09745985 0,12472787 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09745985 0,12466156 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,09745985 0,12459532 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09745985 0,12452915 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09745985 0,12446305 ! sarcomere organization GO:0045214 30 22 0,000 0,09745985 0,12439702 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09745985 0,12433107 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09745985 0,12426518 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09745985 0,12419936 ! protein stabilization GO:0050821 39 22 0,000 0,09745985 0,12413361 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,1016584 0,12941276 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1016584 0,12934433 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1016584 0,12927596 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1016584 0,12920767 ! viral genome replication GO:0019079 41 23 0,000 0,1016584 0,12913945 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1016584 0,1290713 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1016584 0,12900323 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1016584 0,12893522 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1016584 0,12886729 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1016584 0,12879943 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1016584 0,12873164 ! visual behavior GO:0007632 42 23 0,000 0,1016584 0,12866392 ! response to ethanol GO:0045471 46 23 0,000 0,1016584 0,12859628 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1016584 0,1285287 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1016584 0,1284612 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1016584 0,12839376 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1016584 0,1283264 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1016584 0,12825911 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1016584 0,12819189 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,1016584 0,12812474 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1016584 0,12805765 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1016584 0,12799064 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1016584 0,1279237 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1016584 0,12785683 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1016584 0,12779003 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1016584 0,1277233 ! fatty acid transport GO:0015908 44 23 0,000 0,1016584 0,12765664 ! platelet activation GO:0030168 37 23 0,000 0,1016584 0,12759005 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1016584 0,12752353 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1016584 0,12745707 ! hormone transport GO:0009914 40 23 0,000 0,1016584 0,12739069 ! cell-cell recognition GO:0009988 25 23 0,000 0,1016584 0,12732437 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1016584 0,12725813 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1016584 0,12719195 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,1016584 0,12712584 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1016584 0,1270598 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1016584 0,12699383 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,10583757 0,13214592 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10583757 0,13207738 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10583757 0,13200891 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10583757 0,13194052 ! vesicle docking GO:0048278 47 24 0,000 0,10583757 0,13187219 ! spinal cord development GO:0021510 47 24 0,000 0,10583757 0,13180393 ! vacuole organization GO:0007033 43 24 0,000 0,10583757 0,13173574 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10583757 0,13166763 ! digestive system process GO:0022600 39 24 0,000 0,10583757 0,13159958 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10583757 0,13153161 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10583757 0,1314637 ! regulation of behavior GO:0050795 43 24 0,000 0,10583757 0,13139587 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10583757 0,1313281 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10583757 0,13126041 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10583757 0,13119278 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10583757 0,13112523 ! membrane depolarization GO:0051899 39 24 0,000 0,10583757 0,13105774 ! pentose metabolic process GO:0019321 35 24 0,000 0,10583757 0,13099033 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,10583757 0,13092298 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10583757 0,1308557 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10583757 0,13078849 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10583757 0,13072135 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10583757 0,13065428 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10583757 0,13058728 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10583757 0,13052035 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10583757 0,13045348 ! regulation of amine transport GO:0051952 40 24 0,000 0,10583757 0,13038668 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10999743 0,13544208 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10999743 0,1353728 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10999743 0,13530359 ! phototransduction GO:0007602 33 25 0,000 0,10999743 0,13523445 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10999743 0,13516538 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,10999743 0,13509639 ! sperm motility GO:0030317 31 25 0,000 0,10999743 0,13502746 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10999743 0,1349586 ! receptor metabolic process GO:0043112 46 25 0,000 0,10999743 0,13488982 ! chromosome condensation GO:0030261 45 25 0,000 0,10999743 0,1348211 ! neural crest cell development GO:0014032 54 25 0,000 0,10999743 0,13475246 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10999743 0,13468388 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10999743 0,13461537 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10999743 0,13454694 ! interaction with host GO:0051701 62 25 0,000 0,10999743 0,13447857 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10999743 0,13441027 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10999743 0,13434204 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,10999743 0,13427388 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10999743 0,13420579 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10999743 0,13413777 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10999743 0,13406982 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10999743 0,13400194 ! telomere organization GO:0032200 43 25 0,000 0,10999743 0,13393412 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10999743 0,13386638 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10999743 0,1337987 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11413808 0,13876514 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11413808 0,13869506 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11413808 0,13862505 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11413808 0,13855511 ! initiation of viral infection GO:0019059 57 26 0,000 0,11413808 0,13848524 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11413808 0,13841543 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11413808 0,1383457 ! molting cycle process GO:0022404 50 26 0,000 0,11413808 0,13827604 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,11413808 0,13820645 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11413808 0,13813693 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11413808 0,13806748 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11413808 0,1379981 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,11413808 0,13792879 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,11413808 0,13785955 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11413808 0,13779038 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11413808 0,13772127 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11413808 0,13765224 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11413808 0,13758328 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,11413808 0,13751438 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11413808 0,13744556 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,11413808 0,1373768 ! blastocyst development GO:0001824 49 26 0,000 0,11413808 0,13730811 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11413808 0,13723949 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11413808 0,13717094 ! neuron fate commitment GO:0048663 48 27 0,000 0,1182596 0,14205322 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,1182596 0,14198233 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,1182596 0,14191152 ! iron ion transport GO:0006826 59 27 0,000 0,1182596 0,14184078 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1182596 0,1417701 ! protein amino acid acylation GO:0043543 55 27 0,000 0,1182596 0,1416995 ! superoxide metabolic process GO:0006801 38 27 0,000 0,1182596 0,14162897 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1182596 0,14155851 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1182596 0,14148811 ! autophagy GO:0006914 41 27 0,000 0,1182596 0,14141779 ! male gonad development GO:0008584 44 27 0,000 0,1182596 0,14134754 ! response to toxin GO:0009636 47 27 0,000 0,1182596 0,14127736 ! primary neural tube formation GO:0014020 51 27 0,000 0,1182596 0,14120725 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1182596 0,1411372 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1182596 0,14106723 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1182596 0,14099732 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1182596 0,14092749 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1182596 0,14085772 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,12236208 0,14567203 ! circadian rhythm GO:0007623 50 28 0,000 0,12236208 0,14559998 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,12236208 0,14552801 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,12236208 0,14545611 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,12236208 0,14538428 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,12236208 0,14531252 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,12236208 0,14524083 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,12236208 0,14516922 ! synaptogenesis GO:0007416 42 28 0,000 0,12236208 0,14509767 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,12236208 0,14502619 ! lipid oxidation GO:0034440 43 28 0,000 0,12236208 0,14495479 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,12236208 0,14488345 ! translational initiation GO:0006413 65 29 0,000 0,12644561 0,14964493 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12644561 0,14957136 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12644561 0,14949786 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12644561 0,14942443 ! catechol metabolic process GO:0009712 54 29 0,000 0,12644561 0,14935107 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12644561 0,14927779 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12644561 0,14920458 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12644561 0,14913144 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12644561 0,14905837 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12644561 0,14898538 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12644561 0,14891245 ! cell fate determination GO:0001709 60 29 0,000 0,12644561 0,1488396 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12644561 0,14876682 ! detection of light stimulus GO:0009583 38 29 0,000 0,12644561 0,14869411 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12644561 0,14862147 ! regulation of coagulation GO:0050818 46 29 0,000 0,12644561 0,1485489 ! phenol metabolic process GO:0018958 55 30 0,000 0,13051027 0,15324925 ! zinc ion transport GO:0006829 45 30 0,000 0,13051027 0,1531745 ! membrane docking GO:0022406 61 30 0,000 0,13051027 0,15309982 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13051027 0,15302521 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13051027 0,15295067 ! acute-phase response GO:0006953 49 30 0,000 0,13051027 0,1528762 ! myofibril assembly GO:0030239 47 30 0,000 0,13051027 0,15280181 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,13051027 0,15272749 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13051027 0,15265324 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,13051027 0,15257907 ! phospholipid transport GO:0015914 51 30 0,000 0,13051027 0,15250496 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13051027 0,15243093 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13051027 0,15235697 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,13051027 0,15228309 ! eye morphogenesis GO:0048592 60 30 0,000 0,13051027 0,15220927 ! response to heat GO:0009408 50 30 0,000 0,13051027 0,15213552 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,13455616 0,15677585 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,13455616 0,15669996 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,13455616 0,15662415 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,13455616 0,15654842 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,13455616 0,15647275 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,13455616 0,15639716 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,13455616 0,15632164 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,13455616 0,1562462 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,13455616 0,15617083 ! ovulation cycle process GO:0022602 49 31 0,000 0,13455616 0,15609553 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,13455616 0,1560203 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,13455616 0,15594515 ! peptide transport GO:0015833 55 31 0,000 0,13455616 0,15587006 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,13455616 0,15579505 ! mesoderm formation GO:0001707 69 31 0,000 0,13455616 0,15572012 ! natural killer cell activation GO:0030101 45 31 0,000 0,13455616 0,15564525 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,13455616 0,15557046 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,13455616 0,15549574 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,13455616 0,15542109 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13858335 0,15999595 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13858335 0,15991921 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13858335 0,15984255 ! cholesterol transport GO:0030301 56 32 0,000 0,13858335 0,15976596 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13858335 0,15968944 ! spliceosome assembly GO:0000245 67 32 0,000 0,13858335 0,159613 ! spindle organization GO:0007051 46 32 0,000 0,13858335 0,15953663 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13858335 0,15946033 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13858335 0,15938411 ! muscle cell development GO:0055001 49 32 0,000 0,13858335 0,15930795 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13858335 0,15923188 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,13858335 0,15915587 ! ovulation cycle GO:0042698 51 32 0,000 0,13858335 0,15907994 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13858335 0,15900408 ! hindbrain development GO:0030902 61 32 0,000 0,13858335 0,15892829 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13858335 0,15885257 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13858335 0,15877693 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,13858335 0,15870136 ! gene silencing GO:0016458 65 32 0,000 0,13858335 0,15862586 ! post-embryonic development GO:0009791 69 33 0,000 0,14259194 0,16313657 ! protein targeting to membrane GO:0006612 68 33 0,000 0,14259194 0,16305903 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,14259194 0,16298157 ! ceramide metabolic process GO:0006672 64 33 0,000 0,14259194 0,16290418 ! formation of primary germ layer GO:0001704 72 33 0,000 0,14259194 0,16282687 ! cell fate specification GO:0001708 52 33 0,000 0,14259194 0,16274962 ! sterol transport GO:0015918 57 33 0,000 0,14259194 0,16267246 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,14259194 0,16259536 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,14259194 0,16251834 ! adult locomotory behavior GO:0008344 59 33 0,000 0,14259194 0,16244139 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,14259194 0,16236451 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14658201 0,16682891 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14658201 0,16675003 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14658201 0,16667122 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14658201 0,16659249 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,14658201 0,16651384 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14658201 0,16643526 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14658201 0,16635675 ! spermatid development GO:0007286 63 34 0,000 0,14658201 0,16627832 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14658201 0,16619996 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14658201 0,16612167 ! placenta development GO:0001890 53 34 0,000 0,14658201 0,16604346 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,14658201 0,16596532 ! regulation of muscle development GO:0048634 70 35 0,000 0,15055364 0,17038196 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,15055364 0,17030186 ! negative regulation of secretion GO:0051048 63 35 0,000 0,15055364 0,17022183 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,15055364 0,17014187 ! odontogenesis GO:0042476 66 35 0,000 0,15055364 0,17006199 ! female gonad development GO:0008585 58 35 0,000 0,15055364 0,16998219 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,15055364 0,16990246 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 0,000 0,15055364 0,16982281 ! neural tube formation GO:0001841 67 35 0,000 0,15055364 0,16974323 ! vesicle localization GO:0051648 64 35 0,000 0,15055364 0,16966372 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,15450691 0,17403728 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15450691 0,17395584 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,15450691 0,17387448 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,15450691 0,17379319 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15450691 0,17371198 ! positive regulation of cell development GO:0010720 80 36 0,000 0,15450691 0,17363084 ! regulation of proteolysis GO:0030162 72 36 0,000 0,15450691 0,17354978 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15450691 0,1734688 ! aerobic respiration GO:0009060 55 36 0,000 0,15450691 0,17338789 ! embryonic organ development GO:0048568 57 36 0,000 0,15450691 0,17330705 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15844192 0,17763805 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15844192 0,17755532 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,15844192 0,17747266 ! sister chromatid segregation GO:0000819 58 37 0,000 0,15844192 0,17739007 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15844192 0,17730757 ! organic anion transport GO:0015711 68 37 0,000 0,15844192 0,17722513 ! tissue remodeling GO:0048771 76 37 0,000 0,15844192 0,17714278 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15844192 0,1770605 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15844192 0,1769783 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,15844192 0,17689618 ! pigment metabolic process GO:0042440 80 37 0,000 0,15844192 0,17681413 ! spermatid differentiation GO:0048515 66 37 0,000 0,15844192 0,17673216 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,16235875 0,18101721 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,16235875 0,18093337 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,16235875 0,18084961 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,16235875 0,18076592 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,16235875 0,18068231 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,16235875 0,18059877 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,16235875 0,18051532 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,16235875 0,18043194 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,16235875 0,18034864 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,16235875 0,18026541 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,16235875 0,18018226 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,16235875 0,18009919 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 0,000 0,16625747 0,18433893 ! organic ether metabolic process GO:0018904 55 39 0,000 0,16625747 0,18425402 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,16625747 0,18416919 ! segmentation GO:0035282 67 39 0,000 0,16625747 0,18408444 ! ion transmembrane transport GO:0034220 66 39 0,000 0,16625747 0,18399976 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,16625747 0,18391516 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,16625747 0,18383064 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,16625747 0,1837462 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,17013818 0,18794879 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,17013818 0,18786254 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,17013818 0,18777636 ! feeding behavior GO:0007631 59 40 0,000 0,17013818 0,18769027 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,17013818 0,18760425 ! mesenchymal cell development GO:0014031 87 40 0,000 0,17013818 0,18751831 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,17013818 0,18743245 ! cytokinesis GO:0000910 72 40 0,000 0,17013818 0,18734667 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,17400096 0,19151249 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,17400096 0,19142492 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,17400096 0,19133743 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,17400096 0,19125002 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,17400096 0,1911627 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,17400096 0,19107545 ! female gamete generation GO:0007292 61 41 0,000 0,17400096 0,19098828 ! polyol metabolic process GO:0019751 66 41 0,000 0,17400096 0,19090119 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,17784588 0,19503062 ! regulation of tube size GO:0035150 71 42 0,000 0,17784588 0,19494177 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17784588 0,194853 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17784588 0,19476431 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,17784588 0,1946757 ! neuron migration GO:0001764 79 42 0,000 0,17784588 0,19458717 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17784588 0,19449872 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,18167303 0,19859396 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,18167303 0,19850377 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,18167303 0,19841367 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,18167303 0,19832364 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,18167303 0,1982337 ! neural tube development GO:0021915 77 43 0,000 0,18167303 0,19814384 ! striated muscle contraction GO:0006941 77 43 0,000 0,18167303 0,19805406 ! phagocytosis GO:0006909 90 43 0,000 0,18167303 0,19796436 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,18167303 0,19787474 ! male sex differentiation GO:0046661 76 44 0,000 0,18548249 0,20193252 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,18548249 0,20184119 ! developmental growth GO:0048589 82 44 0,000 0,18548249 0,20174994 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18927435 0,20578133 ! glycolysis GO:0006096 65 45 0,000 0,18927435 0,20568838 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,18927435 0,20559552 ! leukocyte migration GO:0050900 68 45 0,000 0,18927435 0,20550274 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,18927435 0,20541005 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18927435 0,20531744 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,18927435 0,20522491 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18927435 0,20513247 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18927435 0,20504011 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,19304868 0,2090347 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,19304868 0,20894067 ! positive regulation of defense response GO:0031349 76 47 0,000 0,19680556 0,21291105 ! endosome transport GO:0016197 108 47 0,000 0,19680556 0,21281536 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,19680556 0,21271975 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,19680556 0,21262423 ! protein homooligomerization GO:0051260 76 47 0,000 0,19680556 0,2125288 ! Notch signaling pathway GO:0007219 96 48 0,000 0,20054507 0,21646992 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,20054507 0,21637284 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,20054507 0,21627586 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,20054507 0,21617896 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2042673 0,22009276 ! regulation of ion transport GO:0043269 77 49 0,000 0,2042673 0,21999424 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,2042673 0,21989581 ! peptide metabolic process GO:0006518 76 49 0,000 0,2042673 0,21979746 ! response to temperature stimulus GO:0009266 76 49 0,000 0,2042673 0,21969921 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2042673 0,21960104 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2042673 0,21950296 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2042673 0,21940497 ! neuromuscular process GO:0050905 99 50 0,000 0,20797232 0,22328488 ! regulation of ossification GO:0030278 117 50 0,000 0,20797232 0,22318528 ! histone modification GO:0016570 91 50 0,000 0,20797232 0,22308578 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,20797232 0,22298637 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,20797232 0,22288704 ! viral infectious cycle GO:0019058 99 51 0,000 0,21166021 0,22673841 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,21166021 0,22663751 ! excretion GO:0007588 83 51 0,000 0,21166021 0,22653669 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,21166021 0,22643596 ! chromatin remodeling GO:0006338 109 51 0,000 0,21166021 0,22633532 ! vesicle organization GO:0016050 107 51 0,000 0,21166021 0,22623477 ! regulation of cell shape GO:0008360 125 51 0,000 0,21166021 0,22613431 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,21166021 0,22603394 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,21533106 0,22985205 ! positive regulation of growth GO:0045927 90 52 0,000 0,21533106 0,22975012 ! covalent chromatin modification GO:0016569 101 52 0,000 0,21533106 0,22964828 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,21533106 0,22954653 ! amino acid activation GO:0043038 92 52 0,000 0,21533106 0,22944487 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,21533106 0,2293433 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,21898493 0,23313174 ! regulation of translational initiation GO:0006446 82 53 0,000 0,21898493 0,23302863 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,21898493 0,23292561 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,21898493 0,23282269 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,21898493 0,23271985 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,21898493 0,2326171 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,22262191 0,23637613 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,22262191 0,23627186 ! cell recognition GO:0008037 85 54 0,000 0,22262191 0,23616769 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,22262191 0,2360636 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,22262191 0,23595961 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,22262191 0,23585571 ! chloride transport GO:0006821 90 55 0,000 0,22624207 0,23958557 ! glucose catabolic process GO:0006007 82 55 0,000 0,22624207 0,23948017 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,22624207 0,23937485 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,22624207 0,23926964 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,22624207 0,23916451 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,22624207 0,23905947 ! gastrulation GO:0007369 112 55 0,000 0,22624207 0,23895453 ! heart morphogenesis GO:0003007 97 55 0,000 0,22624207 0,23884968 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,22624207 0,23874492 ! RNA elongation GO:0006354 79 55 0,000 0,22624207 0,23864025 ! nuclear export GO:0051168 97 55 0,000 0,22624207 0,23853568 ! regulation of actin filament length GO:0030832 105 56 0,000 0,22984549 0,24222876 ! sensory perception of smell GO:0007608 80 56 0,000 0,22984549 0,2421227 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22984549 0,24201674 ! proton transport GO:0015992 94 56 0,000 0,22984549 0,24191087 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,22984549 0,2418051 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,23343225 0,24547116 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,23343225 0,24536392 ! hydrogen transport GO:0006818 97 58 0,000 0,23700243 0,24900779 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,23700243 0,2488991 ! regulation of endocytosis GO:0030100 91 58 0,000 0,23700243 0,24879051 ! adult behavior GO:0030534 99 58 0,000 0,23700243 0,24868201 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,23700243 0,2485736 ! positive regulation of secretion GO:0051047 95 59 0,000 0,2405561 0,25219084 ! regulation of cellular component size GO:0032535 109 59 0,000 0,2405561 0,252081 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,2405561 0,25197125 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,2405561 0,25186161 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,2405561 0,25175205 ! establishment of organelle localization GO:0051656 109 59 0,000 0,2405561 0,2516426 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,24409333 0,25523188 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,24409333 0,255121 ! regulation of heart contraction GO:0008016 110 60 0,000 0,24409333 0,25501023 ! camera-type eye development GO:0043010 116 60 0,000 0,24409333 0,25489954 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,24409333 0,25478896 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2476142 0,25835203 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2476142 0,25824004 ! tRNA processing GO:0008033 89 61 0,000 0,2476142 0,25812815 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2476142 0,25801636 ! viral reproductive process GO:0022415 126 62 0,000 0,2511188 0,2615549 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2511188 0,26144172 ! gonad development GO:0008406 98 62 0,000 0,2511188 0,26132864 ! regulation of mitosis GO:0007088 105 63 0,000 0,25460718 0,2648443 GO:0051783|regulation of nuclear division, ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,25460718 0,26472985 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,25807943 0,26822424 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25807943 0,26810842 ! single fertilization GO:0007338 75 64 0,000 0,25807943 0,26799271 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,26153562 0,2714645 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,26153562 0,27134743 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,26153562 0,27123047 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,26497582 0,27467981 ! extracellular matrix organization GO:0030198 133 66 0,000 0,26497582 0,27456151 ! secondary metabolic process GO:0019748 116 66 0,000 0,26497582 0,27444332 ! cell projection assembly GO:0030031 120 66 0,000 0,26497582 0,27432523 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,26840012 0,27775083 ! chromosome segregation GO:0007059 113 67 0,000 0,26840012 0,27763142 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,26840012 0,27751211 ! hexose catabolic process GO:0019320 104 67 0,000 0,26840012 0,2773929 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,26840012 0,2772738 ! activation of immune response GO:0002253 105 67 0,000 0,26840012 0,2771548 ! amino acid transport GO:0006865 125 68 0,000 0,27180857 0,28055402 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,27180857 0,28043371 ! viral reproduction GO:0016032 134 68 0,000 0,27180857 0,28031351 ! regulation of lipase activity GO:0060191 130 68 0,000 0,27180857 0,28019341 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,27180857 0,28007341 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,27520125 0,28344787 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,27520125 0,28332658 ! antigen processing and presentation GO:0019882 104 69 0,000 0,27520125 0,2832054 ! appendage morphogenesis GO:0035107 135 70 0,000 0,27857824 0,28655804 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,28193961 0,28989176 ! appendage development GO:0048736 136 71 0,000 0,28193961 0,28976792 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,28193961 0,2896442 ! regulation of immune effector process GO:0002697 137 71 0,000 0,28193961 0,28952057 ! acute inflammatory response GO:0002526 113 72 0,000 0,28528543 0,29283138 ! learning or memory GO:0007611 147 73 0,000 0,28861577 0,29612347 ! regulation of blood pressure GO:0008217 125 73 0,000 0,28861577 0,29599725 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,28861577 0,29587113 ! fertilization GO:0009566 90 73 0,000 0,28861577 0,29574512 ! transition metal ion transport GO:0000041 126 74 0,000 0,2919307 0,29901459 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2919307 0,29888735 ! exocytosis GO:0006887 133 74 0,000 0,2919307 0,29876022 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,2919307 0,29863319 ! eye development GO:0001654 143 74 0,000 0,2919307 0,29850628 ! organelle localization GO:0051640 136 74 0,000 0,2919307 0,29837947 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,29523029 0,30162382 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,29523029 0,30149579 ! rhythmic process GO:0048511 128 75 0,000 0,29523029 0,30136788 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,29851462 0,30459126 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,29851462 0,30446214 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,29851462 0,30433313 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,29851462 0,30420423 ! regulation of catabolic process GO:0009894 161 76 0,000 0,29851462 0,30407544 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,30178375 0,30727537 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,30178375 0,30714539 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,30178375 0,30701552 ! blood coagulation GO:0007596 146 78 0,000 0,30503776 0,31019478 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,30503776 0,31006373 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,3082767 0,31322371 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3082767 0,31309149 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,3082767 0,31295939 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,31150066 0,31609894 ! inorganic anion transport GO:0015698 138 80 0,000 0,31150066 0,31596568 ! response to hypoxia GO:0001666 171 81 0,000 0,3147097 0,31908619 ! digestion GO:0007586 112 81 0,000 0,3147097 0,31895179 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,31790389 0,32205337 ! response to oxygen levels GO:0070482 176 83 0,000 0,32108329 0,32513738 ! hemostasis GO:0007599 158 84 0,000 0,32424799 0,32820389 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,32424799 0,32806588 ! nucleosome assembly GO:0006334 122 85 0,000 0,32739803 0,33111377 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,32739803 0,33097465 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 0,000 0,3305335 0,33400403 ! chromatin assembly GO:0031497 124 86 0,000 0,3305335 0,33386381 ! tube morphogenesis GO:0035239 176 86 0,000 0,3305335 0,33372371 ! alcohol catabolic process GO:0046164 130 86 0,000 0,3305335 0,33358372 ! amine transport GO:0015837 155 86 0,000 0,3305335 0,33344385 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,33365445 0,33645122 ! cellular respiration GO:0045333 135 88 0,000 0,33676095 0,3394415 ! regulation of neurological system process GO:0031644 148 88 0,000 0,33676095 0,33929935 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,33676095 0,33915733 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,34293089 0,34522666 ! sterol metabolic process GO:0016125 152 91 0,000 0,34599446 0,34816506 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,34599446 0,34801951 ! regulation of defense response GO:0031347 149 92 0,000 0,34904384 0,35094003 ! nucleosome organization GO:0034728 138 92 0,000 0,34904384 0,35079343 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,34904384 0,35064697 ! vitamin metabolic process GO:0006766 139 92 0,000 0,34904384 0,35050062 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,35207911 0,35340106 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,35510032 0,35628498 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,35810755 0,35915246 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,36110085 0,3620036 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,36110085 0,36185283 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,36408029 0,36468659 ! hormone metabolic process GO:0042445 157 97 0,000 0,36408029 0,36453483 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,36704594 0,3673513 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,36704594 0,36719856 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,36999786 0,36999786