pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6388-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 11,000 1,67E-14 4,079E-11 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 7,000 2,346E-11 2,865E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 7,000 1,427E-10 1,162E-07 ! cell cycle checkpoint GO:0000075 145 71 6,000 2,634E-08 1,609E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 5,688E-08 2,779E-05 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 4,000 7,086E-08 2,885E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 8,742E-08 3,051E-05 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of epithelial cell proliferation GO:0050680 48 19 3,000 1,249E-06 3,813E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 1,519E-06 4,125E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 1,555E-06 3,8E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 1,58E-06 3,509E-04 ! activation of caspase activity GO:0006919 95 50 4,000 2,589E-06 5,272E-04 ! positive regulation of protein ubiquitination GO:0031398 14 7 2,000 2,756E-06 5,18E-04 ! regulation of helicase activity GO:0051095 16 7 2,000 2,756E-06 4,81E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 4,396E-06 7,16E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 4,396E-06 6,712E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 4,396E-06 6,317E-04 ! negative regulation of cell development GO:0010721 83 26 3,000 4,703E-06 6,383E-04 GO:0050768|negative regulation of neurogenesis, ! positive regulation of caspase activity GO:0043280 108 57 4,000 4,994E-06 6,421E-04 GO:0010952|positive regulation of peptidase activity, ! insulin receptor signaling pathway GO:0008286 66 27 3,000 5,503E-06 6,722E-04 ! middle ear morphogenesis GO:0042474 14 9 2,000 6,573E-06 7,647E-04 ! DNA damage response, signal transduction GO:0042770 136 62 4,000 7,585E-06 8,422E-04 ! ear development GO:0043583 114 66 4,000 1,033E-05 1,097E-03 ! negative regulation of cell growth GO:0030308 142 67 4,000 1,112E-05 1,132E-03 ! L-serine metabolic process GO:0006563 21 11 2,000 1,283E-05 1,254E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 1,286E-05 1,208E-03 ! DNA damage checkpoint GO:0000077 78 35 3,000 1,598E-05 1,446E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 1,705E-05 1,488E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of caspase activity GO:0043281 136 74 4,000 1,811E-05 1,525E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 1,811E-05 1,475E-03 ! regulation of endopeptidase activity GO:0052548 141 77 4,000 2,198E-05 1,732E-03 ! meiosis I GO:0007127 74 38 3,000 2,23E-05 1,703E-03 ! DNA integrity checkpoint GO:0031570 82 38 3,000 2,23E-05 1,651E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 2,23E-05 1,602E-03 ! mammary gland development GO:0030879 93 40 3,000 2,743E-05 1,914E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 2,803E-05 1,902E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 2,803E-05 1,851E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 2,811E-05 1,807E-03 ! regulation of peptidase activity GO:0052547 150 82 4,000 2,983E-05 1,869E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 3,163E-05 1,932E-03 GO:0045937|positive regulation of phosphate metabolic process, ! G1/S transition checkpoint GO:0031575 37 15 2,000 3,493E-05 2,081E-03 ! negative regulation of growth GO:0045926 168 85 4,000 3,549E-05 2,064E-03 ! regulation of protein ubiquitination GO:0031396 28 16 2,000 4,285E-05 2,435E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 4,285E-05 2,379E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 4,397E-05 2,387E-03 ! positive regulation of protein modification process GO:0031401 156 90 4,000 4,673E-05 2,482E-03 ! cell growth GO:0016049 90 46 3,000 4,799E-05 2,495E-03 ! gland development GO:0048732 220 91 4,000 4,927E-05 2,508E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 5,187E-05 2,586E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 5,228E-05 2,554E-03 ! response to calcium ion GO:0051592 94 49 3,000 6,169E-05 2,955E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 6,688E-05 3,142E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 8,613E-05 3,97E-03 ! response to UV GO:0009411 120 55 3,000 9,731E-05 4,403E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 1,002E-04 4,449E-03 ! reciprocal meiotic recombination GO:0007131 44 22 2,000 1,156E-04 5,044E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 1,156E-04 4,955E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 2,000 1,156E-04 4,87E-03 ! G1 phase GO:0051318 44 22 2,000 1,156E-04 4,787E-03 ! inner ear receptor cell differentiation GO:0060113 42 22 2,000 1,156E-04 4,708E-03 ! aging GO:0007568 112 58 3,000 1,198E-04 4,8E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 1,51E-04 5,95E-03 ! mechanoreceptor differentiation GO:0042490 48 24 2,000 1,51E-04 5,855E-03 ! skeletal system morphogenesis GO:0048705 118 63 3,000 1,655E-04 6,316E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,71E-04 6,428E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 1,759E-04 6,511E-03 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 1,000 1,849E-04 6,743E-03 ! positive regulation of helicase activity GO:0051096 12 5 1,000 1,849E-04 6,643E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,849E-04 6,547E-03 ! endochondral ossification GO:0001958 17 5 1,000 1,849E-04 6,454E-03 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,849E-04 6,363E-03 ! regulation of chondrocyte differentiation GO:0032330 16 5 1,000 1,849E-04 6,274E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 1,849E-04 6,188E-03 ! stem cell division GO:0017145 11 5 1,000 1,849E-04 6,105E-03 GO:0048103|somatic stem cell division, ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,927E-04 6,278E-03 ! cellular response to nutrient levels GO:0031669 45 27 2,000 2,161E-04 6,948E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 2,161E-04 6,857E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 2,353E-04 7,371E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 2,488E-04 7,693E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,683E-04 8,193E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 2,683E-04 8,092E-03 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 2,766E-04 8,24E-03 ! regulation of interferon-beta production GO:0032648 8 6 1,000 2,766E-04 8,141E-03 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 2,766E-04 8,044E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 2,766E-04 7,949E-03 ! hyperosmotic response GO:0006972 10 6 1,000 2,766E-04 7,857E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,766E-04 7,767E-03 GO:0045686|negative regulation of glial cell differentiation, ! response to exogenous dsRNA GO:0043330 13 6 1,000 2,766E-04 7,678E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 2,766E-04 7,592E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,766E-04 7,508E-03 ! negative regulation of axon extension GO:0030517 24 6 1,000 2,766E-04 7,425E-03 ! determination of adult lifespan GO:0008340 17 6 1,000 2,766E-04 7,344E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 2,766E-04 7,266E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 3,08E-04 8,005E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 3,28E-04 8,434E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 3,28E-04 8,346E-03 ! prostate gland development GO:0030850 14 7 1,000 3,861E-04 9,724E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,861E-04 9,625E-03 ! neuron remodeling GO:0016322 16 7 1,000 3,861E-04 9,528E-03 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 3,861E-04 9,433E-03 ! negative regulation of DNA recombination GO:0045910 16 7 1,000 3,861E-04 9,339E-03 ! rRNA modification GO:0000154 14 7 1,000 3,861E-04 9,248E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 3,861E-04 9,158E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,861E-04 9,07E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,861E-04 8,984E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 3,861E-04 8,899E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 3,955E-04 9,031E-03 ! serine family amino acid metabolic process GO:0009069 56 34 2,000 4,325E-04 9,782E-03 ! meiosis GO:0007126 143 81 3,000 4,351E-04 9,751E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 3,000 4,558E-04 0,01012368 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 4,715E-04 0,01037724 ! response to metal ion GO:0010038 158 84 3,000 4,995E-04 0,01089541 ! regulation of ligase activity GO:0051340 147 84 3,000 4,995E-04 0,010799 ! negative regulation of DNA binding GO:0043392 67 36 2,000 5,127E-04 0,01098781 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 5,134E-04 0,01090541 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 1,000 5,134E-04 0,01081139 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 5,134E-04 0,01071899 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,134E-04 0,01062815 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,134E-04 0,01053884 ! ER overload response GO:0006983 13 8 1,000 5,134E-04 0,01045101 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,134E-04 0,01036464 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 5,134E-04 0,01027969 ! osteoblast development GO:0002076 17 8 1,000 5,134E-04 0,01019611 ! multicellular organismal aging GO:0010259 20 8 1,000 5,134E-04 0,01011388 ! response to tumor cell GO:0002347 16 8 1,000 5,134E-04 0,01003297 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 5,224E-04 0,0101291 ! negative regulation of cell adhesion GO:0007162 94 37 2,000 5,562E-04 0,01069936 ! negative regulation of cell activation GO:0050866 69 37 2,000 5,562E-04 0,01061577 ! mitochondrion organization GO:0007005 159 87 3,000 5,705E-04 0,01080361 ! regulation of DNA binding GO:0051101 167 89 3,000 6,216E-04 0,01168106 ! response to inorganic substance GO:0010035 173 90 3,000 6,483E-04 0,01209052 ! negative regulation of binding GO:0051100 71 39 2,000 6,501E-04 0,01203127 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 6,501E-04 0,01194081 ! RNA methylation GO:0001510 16 9 1,000 6,581E-04 0,01199891 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 6,581E-04 0,01191003 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 6,581E-04 0,01182246 ! regulation of type I interferon production GO:0032479 12 9 1,000 6,581E-04 0,01173616 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 6,581E-04 0,01165112 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 6,581E-04 0,0115673 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 6,581E-04 0,01148467 ! regulation of telomere maintenance GO:0032204 17 9 1,000 6,581E-04 0,01140322 ! nucleus organization GO:0006997 73 40 2,000 7,006E-04 0,01205255 ! regulation of cell adhesion GO:0030155 241 92 3,000 7,042E-04 0,01203098 ! ear morphogenesis GO:0042471 64 42 2,000 8,089E-04 0,01372265 ! regulation of T cell differentiation GO:0045580 78 42 2,000 8,089E-04 0,01362801 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 8,203E-04 0,01372672 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 8,203E-04 0,01363334 ! lung alveolus development GO:0048286 26 10 1,000 8,203E-04 0,01354122 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 8,203E-04 0,01345034 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 8,203E-04 0,01336067 ! motor axon guidance GO:0008045 22 10 1,000 8,203E-04 0,01327219 ! regulation of gliogenesis GO:0014013 23 10 1,000 8,203E-04 0,01318488 GO:0045685|regulation of glial cell differentiation, ! response to dsRNA GO:0043331 23 10 1,000 8,203E-04 0,0130987 ! natural killer cell mediated immunity GO:0002228 19 10 1,000 8,203E-04 0,01301364 GO:0042267|natural killer cell mediated cytotoxicity, ! epithelial cell differentiation GO:0030855 83 43 2,000 8,668E-04 0,0136616 ! regulation of T cell proliferation GO:0042129 80 43 2,000 8,668E-04 0,01357403 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 8,668E-04 0,01348757 ! forebrain development GO:0030900 210 98 3,000 8,923E-04 0,01379736 ! detection of mechanical stimulus GO:0050982 22 11 1,000 9,998E-04 0,01536159 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 9,998E-04 0,01526558 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 1,000 9,998E-04 0,01517076 ! regulation of intracellular pH GO:0051453 21 11 1,000 9,998E-04 0,01507711 ! negative regulation of axonogenesis GO:0050771 37 11 1,000 9,998E-04 0,01498461 ! neuroblast proliferation GO:0007405 25 11 1,000 9,998E-04 0,01489324 ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 9,998E-04 0,01480298 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 9,998E-04 0,01471381 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! positive regulation of JNK cascade GO:0046330 23 11 1,000 9,998E-04 0,0146257 ! regulation of JNK cascade GO:0046328 104 47 2,000 1,125E-03 0,01635276 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,196E-03 0,01728495 ! cellular component disassembly GO:0022411 89 48 2,000 1,196E-03 0,01718327 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 1,196E-03 0,01708279 ! JAK-STAT cascade GO:0007259 82 48 2,000 1,196E-03 0,01698347 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,196E-03 0,01689398 ! hippocampus development GO:0021766 29 12 1,000 1,196E-03 0,01679689 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,196E-03 0,01670091 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,196E-03 0,01660602 ! focal adhesion formation GO:0048041 37 12 1,000 1,196E-03 0,0165122 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 1,000 1,196E-03 0,01641943 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 1,196E-03 0,01632771 ! leukocyte mediated cytotoxicity GO:0001909 28 12 1,000 1,196E-03 0,016237 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,27E-03 0,01713723 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,27E-03 0,01704307 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,346E-03 0,0179749 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 1,41E-03 0,01871868 ! regulation of chemokine production GO:0032642 18 13 1,000 1,41E-03 0,0186175 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 1,41E-03 0,01851741 ! endocrine pancreas development GO:0031018 25 13 1,000 1,41E-03 0,01841838 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 1,000 1,41E-03 0,01832041 ! response to X-ray GO:0010165 28 13 1,000 1,41E-03 0,01822348 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,41E-03 0,01812757 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 1,41E-03 0,01803266 ! negative regulation of immune system process GO:0002683 101 51 2,000 1,426E-03 0,01814563 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 1,509E-03 0,01909634 ! inner ear development GO:0048839 89 53 2,000 1,594E-03 0,02007422 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 1,594E-03 0,01997128 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,594E-03 0,01986938 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 1,64E-03 0,02033941 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 1,64E-03 0,02023668 ! regulation of cellular pH GO:0030641 27 14 1,000 1,64E-03 0,02013499 ! response to gamma radiation GO:0010332 30 14 1,000 1,64E-03 0,02003432 ! regulation of axon extension GO:0030516 43 14 1,000 1,64E-03 0,01993464 ! regulation of angiogenesis GO:0045765 125 54 2,000 1,683E-03 0,02034886 ! regulation of DNA replication GO:0006275 105 56 2,000 1,869E-03 0,02248654 ! lactation GO:0007595 30 15 1,000 1,887E-03 0,0225989 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,887E-03 0,02248866 ! cell killing GO:0001906 32 15 1,000 1,887E-03 0,02237949 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 2,151E-03 0,02538075 ! response to osmotic stress GO:0006970 27 16 1,000 2,151E-03 0,02525873 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,151E-03 0,02513788 ! DNA catabolic process GO:0006308 94 60 2,000 2,278E-03 0,02649726 ! activation of MAPKK activity GO:0000186 43 17 1,000 2,43E-03 0,02813947 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,43E-03 0,02800674 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,43E-03 0,02787525 GO:0031114|regulation of microtubule depolymerization, ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 2,43E-03 0,027745 ! limbic system development GO:0021761 40 18 1,000 2,726E-03 0,03097981 ! response to retinoic acid GO:0032526 31 18 1,000 2,726E-03 0,03083639 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,726E-03 0,03069429 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 2,726E-03 0,03055349 ! lymphocyte mediated immunity GO:0002449 122 65 2,000 2,862E-03 0,03192483 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 2,989E-03 0,03318824 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 3,039E-03 0,03358895 ! neuron maturation GO:0042551 46 19 1,000 3,039E-03 0,03343765 ! response to vitamin A GO:0033189 32 19 1,000 3,039E-03 0,0332877 ! neuromuscular junction development GO:0007528 43 19 1,000 3,039E-03 0,0331391 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 3,039E-03 0,03299181 ! regulation of cellular response to stress GO:0080135 142 68 2,000 3,253E-03 0,0351602 ! detection of external stimulus GO:0009581 102 68 2,000 3,253E-03 0,03500531 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,367E-03 0,03607269 ! response to vitamin GO:0033273 36 20 1,000 3,367E-03 0,03591516 ! pancreas development GO:0031016 40 20 1,000 3,367E-03 0,03575901 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,367E-03 0,03560421 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 3,367E-03 0,03545074 ! response to alkaloid GO:0043279 38 20 1,000 3,367E-03 0,0352986 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 3,367E-03 0,03514775 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 3,367E-03 0,03499818 ! negative regulation of translation GO:0017148 32 20 1,000 3,367E-03 0,03484988 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 3,39E-03 0,03494203 ! urogenital system development GO:0001655 149 69 2,000 3,39E-03 0,03479522 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 3,39E-03 0,03464963 ! lipid phosphorylation GO:0046834 43 21 1,000 3,71E-03 0,03776899 ! cAMP metabolic process GO:0046058 41 21 1,000 3,71E-03 0,03761227 ! plasma membrane fusion GO:0045026 33 21 1,000 3,71E-03 0,03745685 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 3,71E-03 0,03730271 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 3,71E-03 0,03714983 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,71E-03 0,03699819 ! actin filament organization GO:0007015 167 72 2,000 3,822E-03 0,03795894 ! B cell activation GO:0042113 179 72 2,000 3,822E-03 0,03780526 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 3,822E-03 0,03765282 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 3,822E-03 0,0375016 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 3,822E-03 0,0373516 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 4,07E-03 0,03961262 ! cellular response to starvation GO:0009267 37 22 1,000 4,07E-03 0,03945543 ! cell aging GO:0007569 48 22 1,000 4,07E-03 0,03929948 ! activation of JUN kinase activity GO:0007257 47 22 1,000 4,07E-03 0,03914476 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 4,07E-03 0,03899125 ! regulation of transcription factor activity GO:0051090 137 75 2,000 4,287E-03 0,04091055 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 2,000 4,287E-03 0,04075136 ! gluconeogenesis GO:0006094 38 23 1,000 4,445E-03 0,04208861 ! axis specification GO:0009798 43 23 1,000 4,445E-03 0,0419261 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,445E-03 0,04176485 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 1,000 4,445E-03 0,04160483 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 4,445E-03 0,04144603 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,445E-03 0,04128845 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 4,445E-03 0,04113205 ! cell-matrix adhesion GO:0007160 181 76 2,000 4,449E-03 0,04101604 ! positive regulation of ligase activity GO:0051351 130 77 2,000 4,615E-03 0,04238487 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 4,835E-03 0,04424156 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,835E-03 0,04407648 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 4,835E-03 0,04391263 ! pallium development GO:0021543 56 24 1,000 4,835E-03 0,04374999 ! detection of biotic stimulus GO:0009595 34 24 1,000 4,835E-03 0,04358855 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 4,835E-03 0,0434283 ! activation of protein kinase activity GO:0032147 170 80 2,000 5,135E-03 0,04594934 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 5,241E-03 0,0467275 ! negative regulation of DNA replication GO:0008156 45 25 1,000 5,241E-03 0,04655759 ! immunoglobulin production GO:0002377 62 25 1,000 5,241E-03 0,0463889 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 5,241E-03 0,04622143 ! cell-substrate adhesion GO:0031589 189 82 2,000 5,5E-03 0,0483331 ! protein import into nucleus GO:0006606 174 82 2,000 5,5E-03 0,04815986 ! myelination GO:0042552 50 26 1,000 5,661E-03 0,04939658 ! pyruvate metabolic process GO:0006090 43 26 1,000 5,661E-03 0,0492208 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 5,661E-03 0,04904625 ! osteoblast differentiation GO:0001649 63 26 1,000 5,661E-03 0,04887295 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 5,661E-03 0,04870086 ! somatic diversification of immune receptors GO:0002200 63 26 1,000 5,661E-03 0,04852998 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 5,661E-03 0,04836029 ! response to drug GO:0042493 149 83 2,000 5,688E-03 0,04842072 ! nuclear import GO:0051170 177 83 2,000 5,688E-03 0,04825259 ! response to nutrient GO:0007584 135 84 2,000 5,881E-03 0,04971019 ! regulation of neuron differentiation GO:0045664 187 85 2,000 6,077E-03 0,05119016 ! regulation of interferon-gamma production GO:0032649 43 27 1,000 6,097E-03 0,05118655 ! mitochondrial membrane organization GO:0007006 60 27 1,000 6,097E-03 0,05101125 ! response to starvation GO:0042594 47 27 1,000 6,097E-03 0,05083715 ! regulation of chromosome organization GO:0033044 49 27 1,000 6,097E-03 0,05066424 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 6,548E-03 0,05422281 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 6,548E-03 0,05403963 ! negative regulation of protein modification process GO:0031400 66 28 1,000 6,548E-03 0,05385768 ! fat cell differentiation GO:0045444 57 28 1,000 6,548E-03 0,05367695 ! base-excision repair GO:0006284 41 28 1,000 6,548E-03 0,05349742 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 6,548E-03 0,0533191 ! amine biosynthetic process GO:0009309 146 88 2,000 6,688E-03 0,05428155 ! cellular defense response GO:0006968 123 89 2,000 6,9E-03 0,05581367 ! protein localization in nucleus GO:0034504 192 89 2,000 6,9E-03 0,05562947 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 7,013E-03 0,05635542 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 1,000 7,013E-03 0,05617065 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 7,013E-03 0,05598708 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 1,000 7,492E-03 0,05962186 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 7,492E-03 0,05942828 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 7,492E-03 0,05923596 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 7,492E-03 0,05904487 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 7,786E-03 0,06115886 ! cell junction assembly GO:0034329 85 31 1,000 7,986E-03 0,06253524 ! iron ion homeostasis GO:0055072 60 31 1,000 7,986E-03 0,06233545 ! erythrocyte differentiation GO:0030218 62 31 1,000 7,986E-03 0,06213693 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 7,986E-03 0,06193967 ! ensheathment of neurons GO:0007272 64 31 1,000 7,986E-03 0,06174365 GO:0008366|axon ensheathment, ! regulation of T cell activation GO:0050863 175 96 2,000 8,492E-03 0,06544675 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 8,495E-03 0,06526093 ! metanephros development GO:0001656 81 32 1,000 8,495E-03 0,06505635 ! response to mechanical stimulus GO:0009612 60 32 1,000 8,495E-03 0,06485305 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 8,495E-03 0,06465102 ! hexose biosynthetic process GO:0019319 53 32 1,000 8,495E-03 0,06445024 ! peripheral nervous system development GO:0007422 68 32 1,000 8,495E-03 0,0642507 ! transcription initiation GO:0006352 171 97 2,000 8,736E-03 0,06586972 ! regulation of pH GO:0006885 56 33 1,000 9,017E-03 0,06778318 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 9,017E-03 0,06757526 ! response to ionizing radiation GO:0010212 74 33 1,000 9,017E-03 0,06736861 ! regulation of axonogenesis GO:0050770 86 33 1,000 9,017E-03 0,06716321 ! negative regulation of protein transport GO:0051224 74 33 1,000 9,017E-03 0,06695907 ! glial cell differentiation GO:0010001 67 34 1,000 9,554E-03 0,07072833 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 1,000 9,554E-03 0,07051465 ! telencephalon development GO:0021537 81 35 1,000 0,01010442 0,07435273 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01066864 0,07826873 ! cytokine production GO:0001816 68 36 1,000 0,01066864 0,07803439 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01066864 0,07780146 ! cell junction organization GO:0034330 96 37 1,000 0,01124649 0,08177138 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01124649 0,08152873 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01124649 0,08128752 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01124649 0,08104774 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01183786 0,08505847 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 0,01183786 0,08480904 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01183786 0,08456106 ! regulation of protein stability GO:0031647 77 38 1,000 0,01183786 0,08431452 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,0124426 0,08836417 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,0124426 0,08810804 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,0124426 0,08785339 ! mismatch repair GO:0006298 58 40 1,000 0,0130606 0,09195116 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,0130606 0,09168693 ! mRNA catabolic process GO:0006402 79 41 1,000 0,01369174 0,09584216 ! gliogenesis GO:0042063 91 41 1,000 0,01369174 0,09556833 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01369174 0,09529605 ! maintenance of protein location GO:0045185 95 41 1,000 0,01369174 0,09502533 ! RNA modification GO:0009451 64 41 1,000 0,01369174 0,09475613 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,01433588 0,09893378 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01433588 0,09865509 ! T cell differentiation GO:0030217 93 42 1,000 0,01433588 0,09837797 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,01433588 0,0981024 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01499291 0,10231196 GO:0090047|positive regulation of transcription regulator activity, ! glucose transport GO:0015758 66 43 1,000 0,01499291 0,10202696 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01499291 0,10174356 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,0156627 0,10599441 ! hexose transport GO:0008645 68 44 1,000 0,0156627 0,10570161 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,0156627 0,10541042 ! double-strand break repair GO:0006302 85 44 1,000 0,0156627 0,10512083 ! biopolymer methylation GO:0043414 91 45 1,000 0,01634514 0,10940047 ! B cell differentiation GO:0030183 124 45 1,000 0,01634514 0,10910156 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01634514 0,10880428 ! activation of adenylate cyclase activity GO:0007190 94 46 1,000 0,01704009 0,11312215 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01704009 0,11281558 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01704009 0,11251067 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01704009 0,11220741 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,01704009 0,11190578 ! pigmentation GO:0043473 103 46 1,000 0,01704009 0,11160576 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,01846709 0,12062863 ! mitochondrial transport GO:0006839 94 48 1,000 0,01846709 0,12030695 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01846709 0,11998698 ! methylation GO:0032259 97 48 1,000 0,01846709 0,11966872 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,0191989 0,12408176 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,0191989 0,12375437 ! JNK cascade GO:0007254 106 49 1,000 0,0191989 0,1234287 ! regulation of action potential GO:0001508 102 50 1,000 0,01994275 0,12787437 ! endocrine system development GO:0035270 109 50 1,000 0,01994275 0,12753962 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,01994275 0,12720661 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,01994275 0,12687535 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,02069853 0,13134158 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,02069853 0,13100132 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02069853 0,13066281 ! positive regulation of binding GO:0051099 88 52 1,000 0,02146613 0,13515914 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02146613 0,13481168 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02147758 0,13453777 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02147758 0,13419368 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02147758 0,13385135 GO:0045844|positive regulation of striated muscle development, ! neuron fate determination GO:0048664 7 5 0,000 0,02147758 0,13351076 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02147758 0,1331719 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02147758 0,13283476 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02147758 0,13249932 ! polyol transport GO:0015791 12 5 0,000 0,02147758 0,13216557 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02147758 0,13183349 ! response to superoxide GO:0000303 10 5 0,000 0,02147758 0,13150308 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02147758 0,13117433 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02147758 0,13084721 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02147758 0,13052172 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02147758 0,13019784 ! female meiosis GO:0007143 10 5 0,000 0,02147758 0,12987557 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02147758 0,12955489 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02147758 0,12923579 ! hypothalamus development GO:0021854 9 5 0,000 0,02147758 0,12891826 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02147758 0,12860228 ! cobalt ion transport GO:0006824 11 5 0,000 0,02147758 0,12828785 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02147758 0,12797495 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02147758 0,12766358 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02147758 0,12735371 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02147758 0,12704535 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02147758 0,12673848 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02147758 0,12643308 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02147758 0,12612916 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02147758 0,12582669 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02147758 0,12552567 ! transposition GO:0032196 9 5 0,000 0,02147758 0,12522609 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02147758 0,12492793 ! negative chemotaxis GO:0050919 16 5 0,000 0,02147758 0,12463119 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02147758 0,12433585 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02147758 0,12404192 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02147758 0,12374936 ! behavioral response to pain GO:0048266 10 5 0,000 0,02147758 0,12345819 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02147758 0,12316838 ! Notch receptor processing GO:0007220 11 5 0,000 0,02147758 0,12287993 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02147758 0,12259283 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02147758 0,12230706 ! micturition GO:0060073 9 5 0,000 0,02147758 0,12202263 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02147758 0,12173951 ! copulation GO:0007620 9 5 0,000 0,02147758 0,12145771 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02147758 0,12117721 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02147758 0,120898 ! bioluminescence GO:0008218 9 5 0,000 0,02147758 0,12062007 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02147758 0,12034342 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02147758 0,12006803 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02147758 0,1197939 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02147758 0,11952103 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02147758 0,11924939 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02147758 0,11897898 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02147758 0,1187098 ! grooming behavior GO:0007625 6 5 0,000 0,02147758 0,11844183 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02147758 0,11817507 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02147758 0,11790951 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02147758 0,11764514 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02147758 0,11738195 ! response to protozoan GO:0001562 13 5 0,000 0,02147758 0,11711993 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02147758 0,11685909 ! lymph vessel development GO:0001945 10 5 0,000 0,02147758 0,1165994 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02147758 0,11634087 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02147758 0,11608347 ! single strand break repair GO:0000012 8 5 0,000 0,02147758 0,11582722 ! parathyroid gland development GO:0060017 14 5 0,000 0,02147758 0,11557209 ! anagen GO:0042640 7 5 0,000 0,02147758 0,11531809 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02147758 0,1150652 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02147758 0,11481341 ! cytokine secretion GO:0050663 15 5 0,000 0,02147758 0,11456273 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02147758 0,11431314 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02147758 0,11406463 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02147758 0,1138172 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02147758 0,11357084 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02147758 0,11332555 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02147758 0,11308132 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02147758 0,11283813 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02147758 0,11259599 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02147758 0,11235488 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02147758 0,11211481 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02147758 0,11187576 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02147758 0,11163772 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02147758 0,1114007 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02147758 0,11116468 ! microvillus organization GO:0032528 8 5 0,000 0,02147758 0,11092966 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02147758 0,11069563 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02147758 0,11046259 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02147758 0,11023053 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02147758 0,10999943 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02147758 0,10976931 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02147758 0,10954015 ! polyol catabolic process GO:0046174 9 5 0,000 0,02147758 0,10931194 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02147758 0,10908468 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02147758 0,10885836 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02147758 0,10863298 ! muscle cell migration GO:0014812 8 5 0,000 0,02147758 0,10840853 ! mitochondrial fission GO:0000266 8 5 0,000 0,02147758 0,10818501 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02147758 0,10796241 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02147758 0,10774072 ! mRNA transcription GO:0009299 10 5 0,000 0,02147758 0,10751994 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02147758 0,10730006 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02147758 0,10708108 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02147758 0,10686299 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02147758 0,10664579 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02147758 0,10642947 ! monocyte activation GO:0042117 10 5 0,000 0,02147758 0,10621403 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02147758 0,10599946 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02147758 0,10578575 ! response to food GO:0032094 6 5 0,000 0,02147758 0,1055729 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02147758 0,1053609 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02147758 0,10514976 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02147758 0,10493946 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02147758 0,10473 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02147758 0,10452137 ! forebrain neuron development GO:0021884 13 5 0,000 0,02147758 0,10431358 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02147758 0,10410661 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02147758 0,10390046 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02147758 0,10369512 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02147758 0,10349059 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02147758 0,10328687 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02147758 0,10308395 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02147758 0,10288182 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02147758 0,10268049 ! lipid glycosylation GO:0030259 7 5 0,000 0,02147758 0,10247994 ! nucleobase transport GO:0015851 6 5 0,000 0,02147758 0,10228018 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02147758 0,10208119 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02147758 0,10188297 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02147758 0,10168552 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02147758 0,10148884 ! basic amino acid transport GO:0015802 12 5 0,000 0,02147758 0,10129292 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02147758 0,10109775 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02147758 0,10090333 ! actin nucleation GO:0045010 11 5 0,000 0,02147758 0,10070965 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02147758 0,10051672 ! depurination GO:0045007 5 5 0,000 0,02147758 0,10032453 ! depyrimidination GO:0045008 10 5 0,000 0,02147758 0,10013307 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02147758 0,09994234 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02147758 0,09975234 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02147758 0,09956306 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02147758 0,09937449 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02147758 0,09918664 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02147758 0,09899949 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02147758 0,09881305 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02147758 0,09862731 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02147758 0,09844227 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02147758 0,09825792 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02147758 0,09807426 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02147758 0,09789129 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02147758 0,09770899 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02147758 0,09752738 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02147758 0,09734644 ! response to arsenic GO:0046685 11 5 0,000 0,02147758 0,09716617 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02147758 0,09698656 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02147758 0,09680762 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02147758 0,09662934 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02147758 0,09645171 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02147758 0,09627473 ! response to mercury ion GO:0046689 8 5 0,000 0,02147758 0,09609841 ! response to cadmium ion GO:0046686 7 5 0,000 0,02147758 0,09592272 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02147758 0,09574768 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02147758 0,09557328 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02147758 0,09539951 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02147758 0,09522637 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02147758 0,09505386 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02147758 0,09488197 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02147758 0,0947107 ! decidualization GO:0046697 11 5 0,000 0,02147758 0,09454005 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02147758 0,09437002 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02147758 0,09420059 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02147758 0,09403177 ! embryonic cleavage GO:0040016 6 5 0,000 0,02147758 0,09386356 ! peroxisome fission GO:0016559 5 5 0,000 0,02147758 0,09369595 ! histone demethylation GO:0016577 13 5 0,000 0,02147758 0,09352893 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02147758 0,09336251 ! mitotic recombination GO:0006312 9 5 0,000 0,02147758 0,09319668 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02147758 0,09303144 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02147758 0,09286678 ! metaphase plate congression GO:0051310 7 5 0,000 0,02147758 0,0927027 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02147758 0,09253921 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02147758 0,09237629 ! enteric nervous system development GO:0048484 8 5 0,000 0,02147758 0,09221394 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02147758 0,09205216 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02147758 0,09189095 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02147758 0,0917303 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02147758 0,09157021 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02147758 0,09141068 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02147758 0,0912517 ! B cell homeostasis GO:0001782 13 5 0,000 0,02147758 0,09109328 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02147758 0,09093541 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02147758 0,09077808 ! metaphase GO:0051323 11 5 0,000 0,02147758 0,0906213 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02147758 0,09046505 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02147758 0,09030935 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02147758 0,09015418 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02147758 0,08999954 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02147758 0,08984543 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02147758 0,08969185 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02147758 0,08953879 ! response to redox state GO:0051775 6 5 0,000 0,02147758 0,08938625 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02147758 0,08923424 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02147758 0,08908273 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02147758 0,08893175 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02147758 0,08878127 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02147758 0,0886313 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02147758 0,08848184 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02147758 0,08833288 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02147758 0,08818442 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02147758 0,08803646 ! striatum development GO:0021756 14 5 0,000 0,02147758 0,087889 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02147758 0,08774202 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02147758 0,08759554 ! glial cell migration GO:0008347 10 5 0,000 0,02147758 0,08744955 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02147758 0,08730404 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02147758 0,08715902 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02147758 0,08701448 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02147758 0,08687041 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02147758 0,08672683 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02147758 0,08658371 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02147758 0,08644107 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02147758 0,0862989 ! neuroprotection GO:0043526 8 5 0,000 0,02147758 0,08615719 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02147758 0,08601595 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02147758 0,08587517 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02147758 0,08573485 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02147758 0,08559499 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02147758 0,08545559 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02147758 0,08531663 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02147758 0,08517813 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02147758 0,08504008 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02147758 0,08490248 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02147758 0,08476532 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02147758 0,0846286 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02147758 0,08449232 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02147758 0,08435648 ! spindle assembly GO:0051225 6 5 0,000 0,02147758 0,08422108 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02147758 0,08408611 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02147758 0,08395157 ! protein palmitoylation GO:0018345 12 5 0,000 0,02147758 0,08381746 ! drug metabolic process GO:0017144 7 5 0,000 0,02147758 0,08368378 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02147758 0,08355053 ! organ regeneration GO:0031100 7 5 0,000 0,02147758 0,0834177 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02147758 0,08328529 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02147758 0,0831533 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,02224542 0,08598981 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02224542 0,08585397 ! synapse organization GO:0050808 102 53 1,000 0,02224542 0,08571855 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,0230363 0,08862627 ! membrane fusion GO:0006944 122 54 1,000 0,0230363 0,08848692 ! RNA catabolic process GO:0006401 103 55 1,000 0,02383865 0,09142515 ! cell maturation GO:0048469 107 55 1,000 0,02383865 0,09128186 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,02383865 0,091139 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02465236 0,09410268 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02465236 0,09395587 ! muscle fiber development GO:0048747 131 57 1,000 0,02547731 0,09694872 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02547731 0,09679795 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02547731 0,09664764 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02571778 0,09740859 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02571778 0,0972578 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02571778 0,09710748 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02571778 0,09695762 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02571778 0,09680822 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02571778 0,09665929 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02571778 0,09651081 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02571778 0,09636279 ! response to oxygen radical GO:0000305 11 6 0,000 0,02571778 0,09621522 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02571778 0,0960681 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02571778 0,09592143 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02571778 0,09577521 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02571778 0,09562943 ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02571778 0,0954841 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02571778 0,09533921 ! forebrain regionalization GO:0021871 9 6 0,000 0,02571778 0,09519475 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02571778 0,09505074 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02571778 0,09490716 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02571778 0,09476401 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02571778 0,09462129 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02571778 0,094479 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02571778 0,09433714 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02571778 0,09419571 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02571778 0,0940547 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02571778 0,09391411 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02571778 0,09377394 ! malate metabolic process GO:0006108 13 6 0,000 0,02571778 0,09363418 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02571778 0,09349485 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02571778 0,09335593 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02571778 0,09321742 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02571778 0,09307932 ! protein refolding GO:0042026 15 6 0,000 0,02571778 0,09294162 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02571778 0,09280434 ! opsonization GO:0008228 8 6 0,000 0,02571778 0,09266746 ! mating behavior GO:0007617 7 6 0,000 0,02571778 0,09253098 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02571778 0,09239491 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02571778 0,09225923 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02571778 0,09212396 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02571778 0,09198907 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02571778 0,09185459 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02571778 0,09172049 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02571778 0,09158679 ! toxin metabolic process GO:0009404 11 6 0,000 0,02571778 0,09145348 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02571778 0,09132055 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02571778 0,09118801 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02571778 0,09105585 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02571778 0,09092408 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02571778 0,09079268 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02571778 0,09066167 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02571778 0,09053103 ! thymic T cell selection GO:0045061 16 6 0,000 0,02571778 0,09040077 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02571778 0,09027089 ! protein lipoylation GO:0009249 10 6 0,000 0,02571778 0,09014137 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02571778 0,09001223 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02571778 0,08988346 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02571778 0,08975505 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02571778 0,08962702 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02571778 0,08949934 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02571778 0,08937203 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02571778 0,08924508 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02571778 0,08911849 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02571778 0,08899226 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02571778 0,08886639 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02571778 0,08874087 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02571778 0,08861571 ! urea metabolic process GO:0019627 7 6 0,000 0,02571778 0,0884909 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02571778 0,08836644 ! neutrophil activation GO:0042119 7 6 0,000 0,02571778 0,08824233 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02571778 0,08811857 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02571778 0,08799515 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02571778 0,08787208 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02571778 0,08774935 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02571778 0,08762697 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02571778 0,08750493 ! neuron apoptosis GO:0051402 15 6 0,000 0,02571778 0,08738322 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02571778 0,08726186 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02571778 0,08714083 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02571778 0,08702014 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02571778 0,08689978 ! carnitine transport GO:0015879 10 6 0,000 0,02571778 0,08677975 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02571778 0,08666005 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02571778 0,08654069 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02571778 0,08642165 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02571778 0,08630294 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02571778 0,08618455 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02571778 0,08606649 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02571778 0,08594875 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02571778 0,08583134 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02571778 0,08571424 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02571778 0,08559746 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02571778 0,085481 ! neural nucleus development GO:0048857 19 6 0,000 0,02571778 0,08536486 ! response to UV-C GO:0010225 14 6 0,000 0,02571778 0,08524903 ! astrocyte development GO:0014002 16 6 0,000 0,02571778 0,08513352 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02571778 0,08501832 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02571778 0,08490343 ! interaction with symbiont GO:0051702 14 6 0,000 0,02571778 0,08478885 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02571778 0,08467458 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02571778 0,08456062 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02571778 0,08444696 ! response to copper ion GO:0046688 10 6 0,000 0,02571778 0,08433361 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02571778 0,08422056 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02571778 0,08410781 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02571778 0,08399537 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02571778 0,08388323 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02571778 0,08377138 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02571778 0,08365984 ! hair follicle maturation GO:0048820 8 6 0,000 0,02571778 0,08354859 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02571778 0,08343763 ! Schwann cell development GO:0014044 15 6 0,000 0,02571778 0,08332697 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02571778 0,08321661 ! response to pheromone GO:0019236 6 6 0,000 0,02571778 0,08310653 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02571778 0,08299675 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02571778 0,08288725 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02571778 0,08277805 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02571778 0,08266913 ! subpallium development GO:0021544 15 6 0,000 0,02571778 0,0825605 ! neural tube patterning GO:0021532 8 6 0,000 0,02571778 0,08245215 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02571778 0,08234409 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02571778 0,08223631 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02571778 0,08212881 ! G2 phase GO:0051319 16 6 0,000 0,02571778 0,08202159 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02571778 0,08191465 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02571778 0,08180799 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02571778 0,08170161 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02571778 0,0815955 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02571778 0,08148967 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02571778 0,08138412 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02571778 0,08127883 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02571778 0,08117382 ! receptor internalization GO:0031623 11 6 0,000 0,02571778 0,08106908 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02571778 0,08096461 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02571778 0,08086041 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02571778 0,08075648 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02571778 0,08065281 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02571778 0,08054941 ! protein deubiquitination GO:0016579 16 6 0,000 0,02571778 0,08044627 ! protein destabilization GO:0031648 9 6 0,000 0,02571778 0,0803434 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02571778 0,08024079 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02571778 0,08013844 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02571778 0,08003635 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02571778 0,07993453 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02571778 0,07983296 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02571778 0,07973165 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02571778 0,07963059 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02571778 0,07952979 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02571778 0,07942925 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02571778 0,07932896 ! neural plate development GO:0001840 9 6 0,000 0,02571778 0,07922893 ! catecholamine transport GO:0051937 9 6 0,000 0,02571778 0,07912914 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02571778 0,07902961 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02571778 0,07893032 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02571778 0,07883129 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02571778 0,0787325 ! maternal placenta development GO:0001893 12 6 0,000 0,02571778 0,07863396 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02571778 0,07853567 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02571778 0,07843763 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02571778 0,07833982 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02571778 0,07824226 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02571778 0,07814495 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02571778 0,07804787 GO:0055081|anion homeostasis, ! positive regulation of cell migration GO:0030335 137 58 1,000 0,0263134 0,07975639 ! maintenance of location GO:0051235 124 58 1,000 0,0263134 0,07965756 ! lipid modification GO:0030258 112 60 1,000 0,02801855 0,08471449 ! kidney development GO:0001822 133 60 1,000 0,02801855 0,08460978 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02976691 0,08977847 ! tRNA transcription GO:0009304 17 7 0,000 0,02993972 0,09018835 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02993972 0,09007728 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02993972 0,08996648 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02993972 0,08985596 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02993972 0,0897457 ! sleep GO:0030431 16 7 0,000 0,02993972 0,08963572 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02993972 0,08952601 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02993972 0,08941656 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02993972 0,08930738 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02993972 0,08919847 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02993972 0,08908983 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02993972 0,08898145 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02993972 0,08887333 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02993972 0,08876547 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02993972 0,08865788 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02993972 0,08855054 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02993972 0,08844347 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02993972 0,08833665 ! glycolipid transport GO:0046836 11 7 0,000 0,02993972 0,08823009 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02993972 0,08812379 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02993972 0,08801775 ! neuron adhesion GO:0007158 14 7 0,000 0,02993972 0,08791196 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02993972 0,08780642 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02993972 0,08770114 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02993972 0,08759611 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02993972 0,08749133 ! mRNA stabilization GO:0048255 18 7 0,000 0,02993972 0,0873868 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02993972 0,08728252 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02993972 0,08717848 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02993972 0,0870747 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02993972 0,08697116 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02993972 0,08686787 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02993972 0,08676483 ! lipoprotein transport GO:0042953 14 7 0,000 0,02993972 0,08666202 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02993972 0,08655947 ! rhythmic behavior GO:0007622 17 7 0,000 0,02993972 0,08645715 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02993972 0,08635507 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02993972 0,08625324 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02993972 0,08615165 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02993972 0,08605029 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02993972 0,08594918 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02993972 0,0858483 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02993972 0,08574765 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02993972 0,08564725 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02993972 0,08554707 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02993972 0,08544714 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02993972 0,08534743 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02993972 0,08524796 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02993972 0,08514872 ! spinal cord patterning GO:0021511 14 7 0,000 0,02993972 0,08504971 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02993972 0,08495093 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02993972 0,08485238 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02993972 0,08475405 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02993972 0,08465596 ! adrenal gland development GO:0030325 17 7 0,000 0,02993972 0,08455809 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02993972 0,08446045 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02993972 0,08436303 ! ovulation GO:0030728 10 7 0,000 0,02993972 0,08426584 ! adenohypophysis development GO:0021984 11 7 0,000 0,02993972 0,08416887 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02993972 0,08407212 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02993972 0,0839756 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02993972 0,0838793 ! microtubule nucleation GO:0007020 21 7 0,000 0,02993972 0,08378322 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02993972 0,08368735 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02993972 0,08359171 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02993972 0,08349629 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02993972 0,08340108 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02993972 0,08330609 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02993972 0,08321132 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02993972 0,08311676 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02993972 0,08302242 ! galactose metabolic process GO:0006012 13 7 0,000 0,02993972 0,08292829 ! vesicle fusion GO:0006906 20 7 0,000 0,02993972 0,08283437 ! response to dietary excess GO:0002021 8 7 0,000 0,02993972 0,08274067 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02993972 0,08264717 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02993972 0,08255389 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02993972 0,08246082 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02993972 0,08236796 ! organ growth GO:0035265 15 7 0,000 0,02993972 0,08227531 ! nucleoside transport GO:0015858 11 7 0,000 0,02993972 0,08218286 ! nucleoside salvage GO:0043174 11 7 0,000 0,02993972 0,08209063 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02993972 0,0819986 ! male sex determination GO:0030238 15 7 0,000 0,02993972 0,08190677 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02993972 0,08181515 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,02993972 0,08172374 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02993972 0,08163253 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02993972 0,08154153 ! spindle checkpoint GO:0031577 16 7 0,000 0,02993972 0,08145072 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02993972 0,08136012 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02993972 0,08126972 ! monocyte differentiation GO:0030224 16 7 0,000 0,02993972 0,08117952 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02993972 0,08108952 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02993972 0,08099972 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02993972 0,08091012 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02993972 0,08082072 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02993972 0,08073151 ! fibrinolysis GO:0042730 11 7 0,000 0,02993972 0,0806425 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02993972 0,08055369 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02993972 0,08046507 ! eating behavior GO:0042755 8 7 0,000 0,02993972 0,08037665 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02993972 0,08028842 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02993972 0,08020038 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02993972 0,08011254 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02993972 0,08002489 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02993972 0,07993743 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02993972 0,07985016 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02993972 0,07976308 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02993972 0,0796762 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02993972 0,0795895 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02993972 0,07950299 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02993972 0,07941666 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02993972 0,07933053 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02993972 0,07924458 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02993972 0,07915882 ! histone ubiquitination GO:0016574 9 7 0,000 0,02993972 0,07907324 ! regulation of meiosis GO:0040020 12 7 0,000 0,02993972 0,07898785 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02993972 0,07890264 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02993972 0,07881762 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02993972 0,07873278 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02993972 0,07864812 ! transcription termination GO:0006353 14 7 0,000 0,02993972 0,07856364 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02993972 0,07847934 ! anaphase GO:0051322 18 7 0,000 0,02993972 0,07839523 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02993972 0,07831129 ! axonal fasciculation GO:0007413 19 7 0,000 0,02993972 0,07822754 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02993972 0,07814396 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02993972 0,07806056 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02993972 0,07797734 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02993972 0,0778943 ! diuresis GO:0030146 12 7 0,000 0,02993972 0,07781143 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02993972 0,07772874 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02993972 0,07764623 ! antibiotic transport GO:0042891 9 7 0,000 0,02993972 0,07756389 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02993972 0,07748172 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02993972 0,07739973 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02993972 0,07731792 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02993972 0,07723627 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02993972 0,0771548 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02993972 0,0770735 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02993972 0,07699237 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02993972 0,07691141 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02993972 0,07683062 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02993972 0,07675 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02993972 0,07666955 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02993972 0,07658926 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02993972 0,07650915 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02993972 0,0764292 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02993972 0,07634942 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02993972 0,07626981 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02993972 0,07619036 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02993972 0,07611108 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02993972 0,07603196 ! muscle adaptation GO:0043500 13 7 0,000 0,02993972 0,07595301 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02993972 0,07587422 ! retina homeostasis GO:0001895 12 7 0,000 0,02993972 0,07579559 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02993972 0,07571713 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02993972 0,07563883 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02993972 0,07556069 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02993972 0,07548271 ! mesoderm development GO:0007498 128 63 1,000 0,03065703 0,07721146 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,03155763 0,07939783 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,03246861 0,08160577 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,03246861 0,0815219 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,03246861 0,0814382 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,03338985 0,08366299 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,03338985 0,08357727 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03414349 0,0853762 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03414349 0,08528891 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03414349 0,08520179 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03414349 0,08511485 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03414349 0,08502809 ! male meiosis GO:0007140 9 8 0,000 0,03414349 0,0849415 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03414349 0,08485509 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03414349 0,08476885 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03414349 0,08468279 ! meiotic prophase I GO:0007128 14 8 0,000 0,03414349 0,08459691 ! response to zinc ion GO:0010043 12 8 0,000 0,03414349 0,0845112 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03414349 0,08442566 ! oligopeptide transport GO:0006857 16 8 0,000 0,03414349 0,0843403 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03414349 0,0842551 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03414349 0,08417008 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03414349 0,08408523 ! signal peptide processing GO:0006465 12 8 0,000 0,03414349 0,08400056 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03414349 0,08391605 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03414349 0,08383171 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03414349 0,08374754 ! succinate metabolic process GO:0006105 17 8 0,000 0,03414349 0,08366354 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03414349 0,08357971 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03414349 0,08349605 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03414349 0,08341255 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03414349 0,08332922 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03414349 0,08324606 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03414349 0,08316306 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03414349 0,08308023 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03414349 0,08299756 ! reflex GO:0060004 17 8 0,000 0,03414349 0,08291506 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03414349 0,08283272 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03414349 0,08275055 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03414349 0,08266854 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03414349 0,08258668 ! pigment granule organization GO:0048753 17 8 0,000 0,03414349 0,082505 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03414349 0,08242347 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03414349 0,0823421 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03414349 0,0822609 ! histidine catabolic process GO:0006548 10 8 0,000 0,03414349 0,08217985 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03414349 0,08209897 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03414349 0,08201824 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03414349 0,08193767 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03414349 0,08185726 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03414349 0,08177701 ! melanin metabolic process GO:0006582 17 8 0,000 0,03414349 0,08169692 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03414349 0,08161698 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03414349 0,0815372 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03414349 0,08145757 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03414349 0,0813781 ! macrophage activation GO:0042116 13 8 0,000 0,03414349 0,08129878 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03414349 0,08121962 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03414349 0,08114061 ! purine salvage GO:0043101 12 8 0,000 0,03414349 0,08106176 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03414349 0,08098306 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03414349 0,08090451 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03414349 0,08082612 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03414349 0,08074787 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03414349 0,08066978 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03414349 0,08059184 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03414349 0,08051405 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03414349 0,0804364 ! response to UV-B GO:0010224 17 8 0,000 0,03414349 0,08035891 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03414349 0,08028157 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03414349 0,08020438 ! intermediate filament organization GO:0045109 12 8 0,000 0,03414349 0,08012733 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03414349 0,08005043 ! cellular extravasation GO:0045123 13 8 0,000 0,03414349 0,07997368 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03414349 0,07989708 ! response to antibiotic GO:0046677 11 8 0,000 0,03414349 0,07982062 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03414349 0,07974431 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03414349 0,07966815 ! DNA topological change GO:0006265 12 8 0,000 0,03414349 0,07959213 ! response to tropane GO:0014073 15 8 0,000 0,03414349 0,07951626 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03414349 0,07944053 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03414349 0,07936494 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03414349 0,0792895 ! mast cell activation GO:0045576 14 8 0,000 0,03414349 0,0792142 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03414349 0,07913904 ! gas homeostasis GO:0033483 14 8 0,000 0,03414349 0,07906403 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03414349 0,07898916 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03414349 0,07891443 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03414349 0,07883984 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03414349 0,07876539 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03414349 0,07869109 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03414349 0,07861692 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03414349 0,07854289 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03414349 0,078469 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03414349 0,07839526 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03414349 0,07832164 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03414349 0,07824817 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03414349 0,07817484 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03414349 0,07810164 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03414349 0,07802858 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03414349 0,07795566 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03414349 0,07788287 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03414349 0,07781022 ! hormone catabolic process GO:0042447 17 8 0,000 0,03414349 0,0777377 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03414349 0,07766532 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03414349 0,07759307 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03414349 0,07752096 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03414349 0,07744898 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03414349 0,07737714 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03414349 0,07730542 ! adult feeding behavior GO:0008343 10 8 0,000 0,03414349 0,07723384 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03414349 0,0771624 ! ATP catabolic process GO:0006200 11 8 0,000 0,03414349 0,07709108 ! blastocyst growth GO:0001832 19 8 0,000 0,03414349 0,0770199 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03414349 0,07694885 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03414349 0,07687793 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03414349 0,07680714 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03414349 0,07673648 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03414349 0,07666595 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03414349 0,07659555 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03414349 0,07652528 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03414349 0,07645513 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03414349 0,07638512 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03414349 0,07631523 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03414349 0,07624548 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03414349 0,07617585 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03414349 0,07610634 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03414349 0,07603697 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03414349 0,07596772 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03414349 0,07589859 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03414349 0,07582959 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03414349 0,07576072 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03414349 0,07569197 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03414349 0,07562335 ! activation of MAPK activity GO:0000187 124 67 1,000 0,03432127 0,07594823 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03432127 0,0758795 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,03526274 0,07789048 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,03526274 0,07782012 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! adaptive immune response GO:0002250 126 68 1,000 0,03526274 0,07774988 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,03526274 0,07767977 ! lung development GO:0030324 165 69 1,000 0,03621417 0,0797038 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,03621417 0,07963206 ! developmental maturation GO:0021700 128 69 1,000 0,03621417 0,07956045 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,0381465 0,08373036 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,0381465 0,0836552 ! axon extension GO:0048675 16 9 0,000 0,03832916 0,08398039 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03832916 0,08390514 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03832916 0,08383003 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03832916 0,08375504 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03832916 0,0836802 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03832916 0,08360548 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03832916 0,0835309 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03832916 0,08345645 ! reproductive behavior GO:0019098 22 9 0,000 0,03832916 0,08338214 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03832916 0,08330795 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03832916 0,0832339 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03832916 0,08315998 ! UTP metabolic process GO:0046051 10 9 0,000 0,03832916 0,08308619 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03832916 0,08301253 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03832916 0,08293901 ! artery development GO:0060840 25 9 0,000 0,03832916 0,08286561 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03832916 0,08279234 ! regulation of glycolysis GO:0006110 20 9 0,000 0,03832916 0,0827192 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03832916 0,0826462 ! equilibrioception GO:0050957 20 9 0,000 0,03832916 0,08257331 ! chemosensory behavior GO:0007635 21 9 0,000 0,03832916 0,08250056 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03832916 0,08242794 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03832916 0,08235544 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03832916 0,08228307 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03832916 0,08221083 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03832916 0,08213872 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03832916 0,08206673 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03832916 0,08199487 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03832916 0,08192313 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03832916 0,08185152 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03832916 0,08178003 ! protein targeting to ER GO:0045047 25 9 0,000 0,03832916 0,08170867 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03832916 0,08163744 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03832916 0,08156632 ! T cell selection GO:0045058 27 9 0,000 0,03832916 0,08149533 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03832916 0,08142447 ! glycine catabolic process GO:0006546 15 9 0,000 0,03832916 0,08135373 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03832916 0,08128311 ! endosome organization GO:0007032 20 9 0,000 0,03832916 0,08121261 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03832916 0,08114223 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03832916 0,08107198 ! mannose metabolic process GO:0006013 13 9 0,000 0,03832916 0,08100185 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03832916 0,08093184 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03832916 0,08086195 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03832916 0,08079218 ! receptor clustering GO:0043113 20 9 0,000 0,03832916 0,08072253 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03832916 0,08065301 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03832916 0,0805836 ! retinol metabolic process GO:0042572 20 9 0,000 0,03832916 0,08051431 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03832916 0,08044514 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03832916 0,08037609 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03832916 0,08030715 ! macrophage differentiation GO:0030225 15 9 0,000 0,03832916 0,08023834 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03832916 0,08016964 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03832916 0,08010106 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03832916 0,0800326 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03832916 0,07996425 ! response to amine stimulus GO:0014075 13 9 0,000 0,03832916 0,07989602 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03832916 0,07982791 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03832916 0,07975991 ! erythrocyte development GO:0048821 17 9 0,000 0,03832916 0,07969203 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03832916 0,07962427 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03832916 0,07955662 ! renal water homeostasis GO:0003091 15 9 0,000 0,03832916 0,07948908 ! postreplication repair GO:0006301 25 9 0,000 0,03832916 0,07942166 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03832916 0,07935436 ! icosanoid secretion GO:0032309 15 9 0,000 0,03832916 0,07928716 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03832916 0,07922008 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03832916 0,07915312 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03832916 0,07908627 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03832916 0,07901953 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03832916 0,0789529 ! sterol catabolic process GO:0016127 14 9 0,000 0,03832916 0,07888639 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03832916 0,07881998 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03832916 0,07875369 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03832916 0,07868751 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03832916 0,07862144 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03832916 0,07855549 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03832916 0,07848964 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03832916 0,0784239 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03832916 0,07835828 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03832916 0,07829276 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03832916 0,07822735 ! purine base metabolic process GO:0006144 25 9 0,000 0,03832916 0,07816205 ! pigment granule transport GO:0051904 17 9 0,000 0,03832916 0,07809686 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03832916 0,07803178 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03832916 0,07796681 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03832916 0,07790195 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03832916 0,07783719 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03832916 0,07777254 ! mitochondrion localization GO:0051646 18 9 0,000 0,03832916 0,077708 ! carbohydrate transport GO:0008643 114 72 1,000 0,03912719 0,07926013 ! respiratory tube development GO:0030323 171 72 1,000 0,03912719 0,07919446 ! respiratory system development GO:0060541 175 74 1,000 0,04111712 0,08315325 ! reproductive structure development GO:0048608 131 75 1,000 0,04212617 0,08512343 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,04212617 0,08505308 ! axon guidance GO:0007411 162 75 1,000 0,04212617 0,08498284 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04249681 0,08565982 ! regulation of developmental growth GO:0048638 16 10 0,000 0,04249681 0,0855892 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04249681 0,0855187 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04249681 0,08544831 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04249681 0,08537804 ! associative learning GO:0008306 21 10 0,000 0,04249681 0,08530789 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04249681 0,08523785 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04249681 0,08516792 ! phosphate transport GO:0006817 24 10 0,000 0,04249681 0,08509811 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04249681 0,08502842 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04249681 0,08495884 ! CTP metabolic process GO:0046036 11 10 0,000 0,04249681 0,08488937 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04249681 0,08482002 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04249681 0,08475077 ! GTP metabolic process GO:0046039 11 10 0,000 0,04249681 0,08468165 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04249681 0,08461263 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04249681 0,08454373 ! social behavior GO:0035176 29 10 0,000 0,04249681 0,08447494 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04249681 0,08440626 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04249681 0,08433769 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04249681 0,08426924 ! androgen metabolic process GO:0008209 17 10 0,000 0,04249681 0,08420089 ! phospholipid efflux GO:0033700 19 10 0,000 0,04249681 0,08413266 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04249681 0,08406453 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04249681 0,08399652 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04249681 0,08392862 ! pathogenesis GO:0009405 17 10 0,000 0,04249681 0,08386082 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04249681 0,08379314 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04249681 0,08372556 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04249681 0,0836581 ! endoderm development GO:0007492 18 10 0,000 0,04249681 0,08359074 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04249681 0,08352349 ! arginine catabolic process GO:0006527 17 10 0,000 0,04249681 0,08345635 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04249681 0,08338932 ! proline metabolic process GO:0006560 13 10 0,000 0,04249681 0,08332239 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04249681 0,08325557 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04249681 0,08318886 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04249681 0,08312226 ! V(D)J recombination GO:0033151 34 10 0,000 0,04249681 0,08305576 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04249681 0,08298937 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04249681 0,08292308 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04249681 0,0828569 ! B cell proliferation GO:0042100 19 10 0,000 0,04249681 0,08279083 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04249681 0,08272486 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04249681 0,082659 ! multicellular organism growth GO:0035264 19 10 0,000 0,04249681 0,08259324 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04249681 0,08252758 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04249681 0,08246203 ! ruffle organization GO:0031529 17 10 0,000 0,04249681 0,08239659 ! epithelial cell development GO:0002064 21 10 0,000 0,04249681 0,08233124 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04249681 0,08226601 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04249681 0,08220087 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04249681 0,08213584 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04249681 0,08207091 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04249681 0,08200608 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04249681 0,08194136 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04249681 0,08187673 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04249681 0,08181221 ! protein heterooligomerization GO:0051291 17 10 0,000 0,04249681 0,08174779 ! brain morphogenesis GO:0048854 23 10 0,000 0,04249681 0,08168348 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04249681 0,08161926 ! segment specification GO:0007379 15 10 0,000 0,04249681 0,08155514 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04249681 0,08149113 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04249681 0,08142721 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04249681 0,0813634 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04249681 0,08129969 ! DNA ligation GO:0006266 18 10 0,000 0,04249681 0,08123607 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04249681 0,08117256 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04249681 0,08110914 ! melanosome localization GO:0032400 16 10 0,000 0,04249681 0,08104582 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04249681 0,0809826 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04249681 0,08091948 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04249681 0,08085646 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04249681 0,08079354 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04249681 0,08073071 ! induction of an organ GO:0001759 17 10 0,000 0,04249681 0,08066799 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04249681 0,08060536 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04249681 0,08054282 ! protein sumoylation GO:0016925 17 10 0,000 0,04249681 0,08048039 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04249681 0,08041805 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04249681 0,0803558 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04249681 0,08029366 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04249681 0,08023161 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04249681 0,08016965 ! salivary gland development GO:0007431 28 10 0,000 0,04249681 0,08010779 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04249681 0,08004603 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04249681 0,07998436 ! midbrain development GO:0030901 14 10 0,000 0,04249681 0,07992279 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04249681 0,07986131 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04249681 0,07979992 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04249681 0,07973863 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04249681 0,07967744 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04249681 0,07961633 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04249681 0,07955532 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04249681 0,07949441 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04249681 0,07943359 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04249681 0,07937286 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,04249681 0,07931222 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,04249681 0,07925168 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04249681 0,07919123 ! blastocyst formation GO:0001825 18 10 0,000 0,04249681 0,07913087 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04249681 0,0790706 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04249681 0,07901043 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04249681 0,07895034 ! response to nicotine GO:0035094 20 10 0,000 0,04249681 0,07889035 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04249681 0,07883045 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04249681 0,07877064 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,04314446 0,07991048 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,04417192 0,08175151 ! protein oligomerization GO:0051259 149 79 1,000 0,0462539 0,08553995 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04664651 0,08620077 ! respiratory burst GO:0045730 17 11 0,000 0,04664651 0,08613562 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04664651 0,08607056 ! neuron fate specification GO:0048665 18 11 0,000 0,04664651 0,0860056 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04664651 0,08594074 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04664651 0,08587598 ! thyroid gland development GO:0030878 26 11 0,000 0,04664651 0,08581131 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,04664651 0,08574674 ! synapsis GO:0007129 14 11 0,000 0,04664651 0,08568227 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04664651 0,0856179 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04664651 0,08555362 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,04664651 0,08548944 ! response to pain GO:0048265 27 11 0,000 0,04664651 0,08542535 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04664651 0,08536136 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04664651 0,08529747 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04664651 0,08523367 ! bone resorption GO:0045453 16 11 0,000 0,04664651 0,08516997 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,04664651 0,08510636 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04664651 0,08504285 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04664651 0,08497943 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04664651 0,08491611 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04664651 0,08485288 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04664651 0,08478975 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04664651 0,08472671 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04664651 0,08466376 ! UV protection GO:0009650 20 11 0,000 0,04664651 0,08460091 ! adult heart development GO:0007512 16 11 0,000 0,04664651 0,08453815 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04664651 0,08447548 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04664651 0,0844129 ! macroautophagy GO:0016236 19 11 0,000 0,04664651 0,08435042 ! temperature homeostasis GO:0001659 18 11 0,000 0,04664651 0,08428803 ! behavioral fear response GO:0001662 27 11 0,000 0,04664651 0,08422574 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04664651 0,08416353 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04664651 0,08410142 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04664651 0,08403939 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04664651 0,08397746 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04664651 0,08391563 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04664651 0,08385388 ! regulation of organ growth GO:0046620 14 11 0,000 0,04664651 0,08379222 ! pigment granule localization GO:0051875 20 11 0,000 0,04664651 0,08373065 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04664651 0,08366918 ! vasoconstriction GO:0042310 20 11 0,000 0,04664651 0,08360779 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04664651 0,0835465 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04664651 0,08348529 ! embryonic axis specification GO:0000578 19 11 0,000 0,04664651 0,08342417 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04664651 0,08336315 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04664651 0,08330221 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04664651 0,08324136 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04664651 0,0831806 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04664651 0,08311993 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04664651 0,08305934 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04664651 0,08299885 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04664651 0,08293844 ! prophase GO:0051324 17 11 0,000 0,04664651 0,08287812 ! nucleosome positioning GO:0016584 15 11 0,000 0,04664651 0,08281789 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04664651 0,08275775 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04664651 0,08269769 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04664651 0,08263772 ! apical protein localization GO:0045176 18 11 0,000 0,04664651 0,08257784 ! acid secretion GO:0046717 20 11 0,000 0,04664651 0,08251804 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04664651 0,08245834 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04664651 0,08239871 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04664651 0,08233918 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04664651 0,08227973 ! thymus development GO:0048538 29 11 0,000 0,04664651 0,08222036 ! cholesterol efflux GO:0033344 21 11 0,000 0,04664651 0,08216108 ! oocyte development GO:0048599 20 11 0,000 0,04664651 0,08210189 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04664651 0,08204278 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04664651 0,08198376 ! embryonic gut development GO:0048566 19 11 0,000 0,04664651 0,08192482 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04664651 0,08186596 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04664651 0,08180719 ! activation of innate immune response GO:0002218 16 11 0,000 0,04664651 0,08174851 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04664651 0,08168991 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04664651 0,08163139 ! lysogeny GO:0030069 22 11 0,000 0,04664651 0,08157296 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04664651 0,08151461 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04664651 0,08145634 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04664651 0,08139816 ! regulation of embryonic development GO:0045995 35 11 0,000 0,04664651 0,08134006 ! nucleus localization GO:0051647 22 11 0,000 0,04664651 0,08128204 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,04730824 0,08237636 ! muscle cell differentiation GO:0042692 178 81 1,000 0,04837135 0,08416752 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,04837135 0,08410761 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,05052349 0,08778726 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,05052349 0,08772487 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05077834 0,08810475 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05077834 0,08804222 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,05077834 0,08797978 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05077834 0,08791743 ! virus-host interaction GO:0019048 30 12 0,000 0,05077834 0,08785516 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05077834 0,08779299 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05077834 0,0877309 ! protein complex disassembly GO:0043241 28 12 0,000 0,05077834 0,0876689 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05077834 0,08760698 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05077834 0,08754516 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05077834 0,08748342 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05077834 0,08742177 ! T cell proliferation GO:0042098 32 12 0,000 0,05077834 0,0873602 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05077834 0,08729873 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05077834 0,08723733 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05077834 0,08717603 ! drug transport GO:0015893 16 12 0,000 0,05077834 0,08711481 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05077834 0,08705368 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05077834 0,08699263 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05077834 0,08693167 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05077834 0,08687079 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05077834 0,08681 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05077834 0,08674929 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05077834 0,08668867 ! lipid digestion GO:0044241 21 12 0,000 0,05077834 0,08662813 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05077834 0,08656768 ! entry into host cell GO:0030260 34 12 0,000 0,05077834 0,08650731 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05077834 0,08644703 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05077834 0,08638683 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05077834 0,08632671 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05077834 0,08626668 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05077834 0,08620673 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05077834 0,08614687 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05077834 0,08608708 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05077834 0,08602738 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05077834 0,08596777 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05077834 0,08590823 ! cranial nerve development GO:0021545 23 12 0,000 0,05077834 0,08584878 ! fucose catabolic process GO:0019317 25 12 0,000 0,05077834 0,08578941 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 27 12 0,000 0,05077834 0,08573012 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05077834 0,08567092 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05077834 0,08561179 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05077834 0,08555275 ! zymogen activation GO:0031638 18 12 0,000 0,05077834 0,08549379 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05077834 0,08543491 ! T cell homeostasis GO:0043029 28 12 0,000 0,05077834 0,08537611 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05077834 0,08531739 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05077834 0,08525876 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,05077834 0,0852002 ! oocyte differentiation GO:0009994 21 12 0,000 0,05077834 0,08514172 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05077834 0,08508333 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,05077834 0,08502501 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05077834 0,08496677 ! defense response to fungus GO:0050832 15 12 0,000 0,05077834 0,08490862 ! developmental induction GO:0031128 22 12 0,000 0,05077834 0,08485054 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05077834 0,08479254 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05077834 0,08473462 ! response to cold GO:0009409 17 12 0,000 0,05077834 0,08467678 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05077834 0,08461902 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05077834 0,08456134 ! localization within membrane GO:0051668 26 12 0,000 0,05077834 0,08450374 ! T cell activation GO:0042110 189 84 1,000 0,05161234 0,08583319 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,05270959 0,08759832 ! negative regulation of transport GO:0051051 164 85 1,000 0,05270959 0,08753877 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,05381514 0,08931412 ! regulation of lyase activity GO:0051339 169 86 1,000 0,05381514 0,08925349 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05489238 0,09097835 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05489238 0,09091667 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05489238 0,09085508 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05489238 0,09079356 ! peroxisomal transport GO:0043574 28 13 0,000 0,05489238 0,09073213 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05489238 0,09067079 ! cartilage condensation GO:0001502 22 13 0,000 0,05489238 0,09060952 ! organelle fusion GO:0048284 36 13 0,000 0,05489238 0,09054834 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05489238 0,09048724 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05489238 0,09042623 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05489238 0,09036529 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05489238 0,09030444 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05489238 0,09024367 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05489238 0,09018298 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05489238 0,09012237 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05489238 0,09006185 ! methionine metabolic process GO:0006555 31 13 0,000 0,05489238 0,0900014 ! plasma membrane organization GO:0007009 27 13 0,000 0,05489238 0,08994104 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05489238 0,08988076 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05489238 0,08982056 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05489238 0,08976044 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05489238 0,0897004 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05489238 0,08964044 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05489238 0,08958056 ! exocrine system development GO:0035272 34 13 0,000 0,05489238 0,08952076 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05489238 0,08946104 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05489238 0,0894014 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05489238 0,08934183 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,05489238 0,08928235 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,05489238 0,08922295 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05489238 0,08916363 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05489238 0,08910438 ! protein homotetramerization GO:0051289 24 13 0,000 0,05489238 0,08904521 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05489238 0,08898613 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05489238 0,08892712 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05489238 0,08886819 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05489238 0,08880933 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05489238 0,08875056 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05489238 0,08869186 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,05489238 0,08863324 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05489238 0,0885747 ! histone methylation GO:0016571 29 13 0,000 0,05489238 0,08851623 ! chromatin silencing GO:0006342 29 13 0,000 0,05489238 0,08845784 ! gland morphogenesis GO:0022612 31 13 0,000 0,05489238 0,08839953 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05489238 0,0883413 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05489238 0,08828314 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05489238 0,08822506 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05489238 0,08816706 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05489238 0,08810913 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05489238 0,08805128 ! spleen development GO:0048536 24 13 0,000 0,05489238 0,0879935 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05489238 0,0879358 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05489238 0,08787817 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05489238 0,08782062 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05489238 0,08776315 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05489238 0,08770575 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05489238 0,08764843 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05489238 0,08759118 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05489238 0,087534 ! insulin secretion GO:0030073 24 13 0,000 0,05489238 0,0874769 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05489238 0,08741988 ! acrosome reaction GO:0007340 19 13 0,000 0,05489238 0,08736293 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05489238 0,08730605 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05489238 0,08724925 ! regulation of protein transport GO:0051223 165 87 1,000 0,0549289 0,08725052 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,05605078 0,0889747 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,0571807 0,09070938 ! response to unfolded protein GO:0006986 139 90 1,000 0,05831855 0,09245439 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,05831855 0,09239443 ! rRNA transcription GO:0009303 28 14 0,000 0,05898871 0,0933956 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05898871 0,09333512 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05898871 0,0932747 ! water transport GO:0006833 21 14 0,000 0,05898871 0,09321437 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05898871 0,09315412 ! non-recombinational repair GO:0000726 29 14 0,000 0,05898871 0,09309394 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05898871 0,09303384 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05898871 0,09297382 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05898871 0,09291387 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05898871 0,09285401 ! lipid localization GO:0010876 32 14 0,000 0,05898871 0,09279422 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05898871 0,0927345 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05898871 0,09267487 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05898871 0,09261531 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05898871 0,09255582 ! arginine metabolic process GO:0006525 21 14 0,000 0,05898871 0,09249642 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05898871 0,09243709 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05898871 0,09237783 ! regulation of heart rate GO:0002027 25 14 0,000 0,05898871 0,09231865 ! fear response GO:0042596 34 14 0,000 0,05898871 0,09225955 ! organic alcohol transport GO:0015850 29 14 0,000 0,05898871 0,09220052 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05898871 0,09214157 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05898871 0,0920827 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05898871 0,09202389 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05898871 0,09196517 ! bone mineralization GO:0030282 18 14 0,000 0,05898871 0,09190652 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05898871 0,09184794 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05898871 0,09178944 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05898871 0,09173101 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05898871 0,09167266 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05898871 0,09161438 ! ribosome assembly GO:0042255 18 14 0,000 0,05898871 0,09155617 ! cerebellum development GO:0021549 23 14 0,000 0,05898871 0,09149804 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05898871 0,09143999 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05898871 0,091382 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05898871 0,09132409 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05898871 0,09126626 ! NADP metabolic process GO:0006739 24 14 0,000 0,05898871 0,09120849 ! oxygen transport GO:0015671 22 14 0,000 0,05898871 0,0911508 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05898871 0,09109318 ! male genitalia development GO:0030539 26 14 0,000 0,05898871 0,09103564 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05898871 0,09097817 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05898871 0,09092077 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05898871 0,09086344 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,05946425 0,09153823 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,05946425 0,09148059 ! defense response to bacterium GO:0042742 112 91 1,000 0,05946425 0,09142302 ! bone development GO:0060348 206 92 1,000 0,06061772 0,09313779 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,06177887 0,09486221 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,06177887 0,09480262 GO:0010498|proteasomal protein catabolic process, ! female pregnancy GO:0007565 166 94 1,000 0,0629476 0,09653546 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,0629476 0,09647489 ! regulation of membrane potential GO:0042391 179 94 1,000 0,0629476 0,09641441 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0630674 0,09653737 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,0630674 0,09647693 ! reproductive cellular process GO:0048610 22 15 0,000 0,0630674 0,09641655 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0630674 0,09635625 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0630674 0,09629603 ! superoxide anion generation GO:0042554 22 15 0,000 0,0630674 0,09623588 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0630674 0,09617581 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0630674 0,09611581 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0630674 0,09605589 ! copper ion transport GO:0006825 22 15 0,000 0,0630674 0,09599604 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0630674 0,09593627 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0630674 0,09587657 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0630674 0,09581695 ! sulfate transport GO:0008272 27 15 0,000 0,0630674 0,0957574 ! response to cAMP GO:0051591 25 15 0,000 0,0630674 0,09569792 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0630674 0,09563852 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0630674 0,09557919 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0630674 0,09551993 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0630674 0,09546075 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0630674 0,09540164 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0630674 0,09534261 ! vesicle coating GO:0006901 38 15 0,000 0,0630674 0,09528364 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0630674 0,09522475 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0630674 0,09516594 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0630674 0,09510719 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0630674 0,09504852 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0630674 0,09498992 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0630674 0,09493139 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0630674 0,09487294 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0630674 0,09481455 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0630674 0,09475624 ! histone deacetylation GO:0016575 24 15 0,000 0,0630674 0,094698 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0630674 0,09463983 ! water homeostasis GO:0030104 28 15 0,000 0,0630674 0,09458174 ! cofactor transport GO:0051181 30 15 0,000 0,0630674 0,09452371 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0630674 0,09446576 ! muscle maintenance GO:0046716 26 15 0,000 0,0630674 0,09440787 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0630674 0,09435006 ! intestinal absorption GO:0050892 31 15 0,000 0,0630674 0,09429232 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0630674 0,09423465 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0630674 0,09417705 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0630674 0,09411952 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0630674 0,09406206 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0630674 0,09400467 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0630674 0,09394735 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0630674 0,0938901 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0630674 0,09383292 ! actin filament polymerization GO:0030041 27 15 0,000 0,0630674 0,09377581 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0630674 0,09371877 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,06412383 0,09523071 ! sex differentiation GO:0007548 171 96 1,000 0,06530748 0,09692963 ! response to protein stimulus GO:0051789 158 96 1,000 0,06530748 0,09687078 ! regulation of protein localization GO:0032880 188 97 1,000 0,06649846 0,09857752 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06712852 0,09945117 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06712852 0,09939089 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06712852 0,09933069 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06712852 0,09927056 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06712852 0,09921051 ! bone remodeling GO:0046849 28 16 0,000 0,06712852 0,09915053 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06712852 0,09909062 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06712852 0,09903078 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06712852 0,09897102 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06712852 0,09891132 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06712852 0,0988517 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06712852 0,09879215 ! startle response GO:0001964 28 16 0,000 0,06712852 0,09873267 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06712852 0,09867327 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06712852 0,09861393 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06712852 0,09855467 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06712852 0,09849548 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06712852 0,09843636 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06712852 0,09837731 ! pituitary gland development GO:0021983 30 16 0,000 0,06712852 0,09831833 ! lysosomal transport GO:0007041 31 16 0,000 0,06712852 0,09825942 ! fructose metabolic process GO:0006000 25 16 0,000 0,06712852 0,09820058 ! L-amino acid transport GO:0015807 33 16 0,000 0,06712852 0,09814181 ! stem cell development GO:0048864 46 16 0,000 0,06712852 0,09808312 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06712852 0,09802449 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06712852 0,09796593 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06712852 0,09790745 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06712852 0,09784903 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06712852 0,09779068 ! axon cargo transport GO:0008088 46 16 0,000 0,06712852 0,0977324 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06712852 0,09767419 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06712852 0,09761605 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06712852 0,09755798 ! DNA replication initiation GO:0006270 28 16 0,000 0,06712852 0,09749998 ! neuron recognition GO:0008038 40 16 0,000 0,06712852 0,09744205 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06712852 0,09738419 ! tissue regeneration GO:0042246 27 16 0,000 0,06712852 0,09732639 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06712852 0,09726867 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06712852 0,09721101 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06712852 0,09715342 ! biomineral formation GO:0031214 22 16 0,000 0,06712852 0,0970959 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06712852 0,09703845 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06712852 0,09698106 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06712852 0,09692374 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06712852 0,09686649 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06712852 0,09680931 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06712852 0,0967522 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06712852 0,09669515 ! peptide hormone processing GO:0016486 27 16 0,000 0,06712852 0,09663817 ! leukocyte differentiation GO:0002521 232 98 1,000 0,06769669 0,09739871 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,06769669 0,09734138 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,07011454 0,10075872 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 1,000 0,07011454 0,10069949 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,07117215 0,10215838 ! metencephalon development GO:0022037 32 17 0,000 0,07117215 0,1020984 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07117215 0,10203848 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,07117215 0,10197863 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,07117215 0,10191886 ! signal complex assembly GO:0007172 47 17 0,000 0,07117215 0,10185915 ! filopodium assembly GO:0046847 42 17 0,000 0,07117215 0,10179951 ! endothelial cell migration GO:0043542 31 17 0,000 0,07117215 0,10173995 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07117215 0,10168045 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07117215 0,10162102 ! glial cell development GO:0021782 28 17 0,000 0,07117215 0,10156166 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,07117215 0,10150238 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07117215 0,10144316 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07117215 0,101384 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,07117215 0,10132492 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07117215 0,10126591 ! myoblast differentiation GO:0045445 50 17 0,000 0,07117215 0,10120697 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,07117215 0,10114809 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,07117215 0,10108928 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,07117215 0,10103055 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,07117215 0,10097187 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,07117215 0,10091327 ! NAD metabolic process GO:0019674 33 17 0,000 0,07117215 0,10085474 ! membrane budding GO:0006900 42 17 0,000 0,07117215 0,10079627 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07117215 0,10073787 ! regulation of protein binding GO:0043393 33 17 0,000 0,07117215 0,10067954 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07117215 0,10062128 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07117215 0,10056308 ! genitalia development GO:0048806 32 17 0,000 0,07117215 0,10050495 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07117215 0,10044689 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,07117215 0,1003889 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07117215 0,10033097 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,07117215 0,10027311 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,07117215 0,10021531 ! steroid catabolic process GO:0006706 34 17 0,000 0,07117215 0,10015759 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07117215 0,10009992 ! gas transport GO:0015669 26 17 0,000 0,07117215 0,10004233 ! organic cation transport GO:0015695 32 17 0,000 0,07117215 0,0999848 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,07117215 0,09992734 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07117215 0,09986994 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,07117215 0,09981261 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07519837 0,10539852 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07519837 0,10533809 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07519837 0,10527772 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07519837 0,10521742 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07519837 0,1051572 ! adult walking behavior GO:0007628 36 18 0,000 0,07519837 0,10509704 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07519837 0,10503695 ! heart looping GO:0001947 34 18 0,000 0,07519837 0,10497693 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07519837 0,10491697 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07519837 0,10485709 ! centrosome cycle GO:0007098 26 18 0,000 0,07519837 0,10479727 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07519837 0,10473753 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07519837 0,10467785 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,07519837 0,10461824 ! glycine metabolic process GO:0006544 30 18 0,000 0,07519837 0,10455869 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07519837 0,10449922 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,07519837 0,10443981 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07519837 0,10438047 ! DNA integration GO:0015074 32 18 0,000 0,07519837 0,10432119 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07519837 0,10426199 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07519837 0,10420285 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07519837 0,10414378 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07519837 0,10408477 ! neural crest cell migration GO:0001755 41 18 0,000 0,07519837 0,10402583 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07519837 0,10396696 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07519837 0,10390816 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07519837 0,10384942 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07519837 0,10379075 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07519837 0,10373214 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07519837 0,1036736 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,07519837 0,10361513 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07519837 0,10355672 ! detection of bacterium GO:0016045 22 18 0,000 0,07519837 0,10349838 ! nerve development GO:0021675 34 18 0,000 0,07519837 0,1034401 ! defense response to virus GO:0051607 43 18 0,000 0,07519837 0,10338189 ! microspike assembly GO:0030035 46 18 0,000 0,07519837 0,10332375 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07519837 0,10326567 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07920725 0,10870973 ! positive regulation of translation GO:0045727 31 19 0,000 0,07920725 0,10864869 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07920725 0,10858772 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07920725 0,10852682 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,07920725 0,10846598 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07920725 0,10840522 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07920725 0,10834452 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07920725 0,10828389 ! inositol metabolic process GO:0006020 33 19 0,000 0,07920725 0,10822333 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07920725 0,10816284 ! memory GO:0007613 34 19 0,000 0,07920725 0,10810241 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07920725 0,10804205 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07920725 0,10798176 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07920725 0,10792154 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07920725 0,10786138 ! cerebral cortex development GO:0021987 40 19 0,000 0,07920725 0,10780129 ! pigmentation during development GO:0048066 42 19 0,000 0,07920725 0,10774127 ! heme metabolic process GO:0042168 40 19 0,000 0,07920725 0,10768131 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07920725 0,10762142 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,07920725 0,1075616 ! response to fungus GO:0009620 26 19 0,000 0,07920725 0,10750184 ! peptide cross-linking GO:0018149 39 19 0,000 0,07920725 0,10744215 ! protein export from nucleus GO:0006611 40 19 0,000 0,07920725 0,10738253 ! heart process GO:0003015 32 19 0,000 0,07920725 0,10732297 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07920725 0,10726348 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07920725 0,10720405 ! visual learning GO:0008542 38 19 0,000 0,07920725 0,10714469 ! cellular pigmentation GO:0033059 37 19 0,000 0,07920725 0,1070854 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07920725 0,10702617 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07920725 0,10696701 ! vitamin transport GO:0051180 31 19 0,000 0,07920725 0,10690791 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07920725 0,10684888 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07920725 0,10678991 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07920725 0,10673101 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07920725 0,10667217 ! cilium assembly GO:0042384 38 19 0,000 0,07920725 0,1066134 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07920725 0,10655469 ! protein secretion GO:0009306 45 20 0,000 0,08319886 0,11186287 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08319886 0,11180134 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08319886 0,11173987 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08319886 0,11167848 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08319886 0,11161715 ! skin development GO:0043588 42 20 0,000 0,08319886 0,11155589 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08319886 0,11149469 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08319886 0,11143357 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,08319886 0,11137251 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,08319886 0,11131152 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08319886 0,11125059 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08319886 0,11118973 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,08319886 0,11112894 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,08319886 0,11106821 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08319886 0,11100755 ! retinoid metabolic process GO:0001523 34 20 0,000 0,08319886 0,11094696 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08319886 0,11088643 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08319886 0,11082597 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,08319886 0,11076557 ! body fluid secretion GO:0007589 33 20 0,000 0,08319886 0,11070524 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08319886 0,11064498 ! peptide secretion GO:0002790 38 20 0,000 0,08319886 0,11058478 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08319886 0,11052465 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08319886 0,11046458 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08319886 0,11040458 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08319886 0,11034464 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08319886 0,11028477 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08319886 0,11022496 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08319886 0,11016522 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08319886 0,11010554 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08319886 0,11004593 ! regulation of glucose import GO:0046324 30 20 0,000 0,08319886 0,10998638 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08319886 0,10992689 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08319886 0,10986747 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08319886 0,10980812 ! regulation of cell killing GO:0031341 46 21 0,000 0,08717329 0,11499154 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08717329 0,11492949 ! hormone secretion GO:0046879 39 21 0,000 0,08717329 0,1148675 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08717329 0,11480557 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08717329 0,11474372 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08717329 0,11468193 ! ovarian follicle development GO:0001541 39 21 0,000 0,08717329 0,1146202 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08717329 0,11455855 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,08717329 0,11449696 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08717329 0,11443543 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08717329 0,11437397 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08717329 0,11431258 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08717329 0,11425126 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08717329 0,11418999 ! sensory perception of pain GO:0019233 33 21 0,000 0,08717329 0,1141288 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08717329 0,11406767 ! diencephalon development GO:0021536 36 21 0,000 0,08717329 0,11400661 ! collagen fibril organization GO:0030199 62 21 0,000 0,08717329 0,11394561 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08717329 0,11388467 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08717329 0,11382381 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08717329 0,113763 ! collagen catabolic process GO:0030574 29 21 0,000 0,08717329 0,11370226 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08717329 0,11364159 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08717329 0,11358098 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08717329 0,11352044 ! actin filament-based movement GO:0030048 47 21 0,000 0,08717329 0,11345996 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,09113059 0,11854741 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09113059 0,11848432 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09113059 0,11842129 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09113059 0,11835834 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09113059 0,11829545 ! microtubule-based transport GO:0010970 59 22 0,000 0,09113059 0,11823263 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,09113059 0,11816987 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,09113059 0,11810718 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,09113059 0,11804456 ! vacuolar transport GO:0007034 41 22 0,000 0,09113059 0,117982 ! central nervous system neuron development GO:0021954 47 22 0,000 0,09113059 0,11791951 ! fucose metabolic process GO:0006004 44 22 0,000 0,09113059 0,11785709 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09113059 0,11779473 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09113059 0,11773243 ! ureteric bud development GO:0001657 50 22 0,000 0,09113059 0,11767021 ! stem cell differentiation GO:0048863 57 22 0,000 0,09113059 0,11760805 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,09113059 0,11754595 ! cytolysis GO:0019835 27 22 0,000 0,09113059 0,11748392 ! renal system process GO:0003014 42 22 0,000 0,09113059 0,11742196 ! vasodilation GO:0042311 40 22 0,000 0,09113059 0,11736006 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09113059 0,11729823 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,09113059 0,11723646 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09113059 0,11717476 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,09113059 0,11711312 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,09113059 0,11705154 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09113059 0,11699003 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,09113059 0,11692859 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09113059 0,11686721 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09113059 0,11680589 ! sarcomere organization GO:0045214 32 22 0,000 0,09113059 0,11674464 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,09113059 0,11668346 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09113059 0,11662233 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,09113059 0,11656127 ! gut development GO:0048565 44 22 0,000 0,09113059 0,11650028 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09113059 0,11643935 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,09113059 0,11637848 ! protein stabilization GO:0050821 41 22 0,000 0,09113059 0,11631768 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,09507085 0,1212836 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,09507085 0,1212203 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09507085 0,12115706 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09507085 0,12109389 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09507085 0,12103079 ! viral genome replication GO:0019079 44 23 0,000 0,09507085 0,12096775 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,09507085 0,12090478 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09507085 0,12084188 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,09507085 0,12077904 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09507085 0,12071626 ! regeneration GO:0031099 42 23 0,000 0,09507085 0,12065355 ! visual behavior GO:0007632 46 23 0,000 0,09507085 0,12059091 ! response to ethanol GO:0045471 47 23 0,000 0,09507085 0,12052833 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09507085 0,12046581 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09507085 0,12040336 ! peroxisome organization GO:0007031 43 23 0,000 0,09507085 0,12034098 ! lysosome organization GO:0007040 47 23 0,000 0,09507085 0,12027866 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,09507085 0,1202164 ! vesicle targeting GO:0006903 49 23 0,000 0,09507085 0,12015421 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09507085 0,12009208 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09507085 0,12003002 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,09507085 0,11996802 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09507085 0,11990609 ! DNA modification GO:0006304 36 23 0,000 0,09507085 0,11984421 ! fatty acid transport GO:0015908 47 23 0,000 0,09507085 0,11978241 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09507085 0,11972066 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09507085 0,11965898 ! hormone transport GO:0009914 41 23 0,000 0,09507085 0,11959737 ! cell-cell recognition GO:0009988 28 23 0,000 0,09507085 0,11953581 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,09507085 0,11947433 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09507085 0,1194129 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,09507085 0,11935154 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,09899414 0,12421298 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,09899414 0,12414922 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,09899414 0,12408552 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,09899414 0,12402189 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,09899414 0,12395832 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,09899414 0,12389481 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,09899414 0,12383138 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,09899414 0,123768 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,09899414 0,1237047 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,09899414 0,12364145 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,09899414 0,12357827 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,09899414 0,12351516 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,09899414 0,12345211 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,09899414 0,12338912 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,09899414 0,1233262 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,09899414 0,12326334 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,09899414 0,12320055 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,09899414 0,12313782 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,09899414 0,12307515 ! membrane depolarization GO:0051899 45 24 0,000 0,09899414 0,12301255 ! oogenesis GO:0048477 44 24 0,000 0,09899414 0,12295001 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,09899414 0,12288754 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,09899414 0,12282513 ! platelet activation GO:0030168 41 24 0,000 0,09899414 0,12276278 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,09899414 0,1227005 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,09899414 0,12263828 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,09899414 0,12257612 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,09899414 0,12251402 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,09899414 0,12245199 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,09899414 0,12239002 ! regulation of amine transport GO:0051952 41 24 0,000 0,09899414 0,12232811 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,10290053 0,12709099 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,10290053 0,12702677 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,10290053 0,12696262 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10290053 0,12689853 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10290053 0,1268345 ! phototransduction GO:0007602 37 25 0,000 0,10290053 0,12677054 ! keratinization GO:0031424 37 25 0,000 0,10290053 0,12670665 ! vasculogenesis GO:0001570 49 25 0,000 0,10290053 0,12664281 ! vacuole organization GO:0007033 49 25 0,000 0,10290053 0,12657905 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10290053 0,12651534 ! receptor metabolic process GO:0043112 53 25 0,000 0,10290053 0,1264517 ! chromosome condensation GO:0030261 48 25 0,000 0,10290053 0,12638813 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,10290053 0,12632462 ! regulation of behavior GO:0050795 48 25 0,000 0,10290053 0,12626117 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,10290053 0,12619778 ! interaction with host GO:0051701 66 25 0,000 0,10290053 0,12613446 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,10290053 0,12607121 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10290053 0,12600801 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,10290053 0,12594488 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,10290053 0,12588182 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10290053 0,12581881 ! liver development GO:0001889 55 25 0,000 0,10290053 0,12575587 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,10679009 0,13044409 ! initiation of viral infection GO:0019059 60 26 0,000 0,10679009 0,1303789 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10679009 0,13031378 ! molting cycle process GO:0022404 52 26 0,000 0,10679009 0,13024872 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10679009 0,13018372 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,10679009 0,13011879 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,10679009 0,13005393 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,10679009 0,12998913 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,10679009 0,12992439 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,10679009 0,12985972 ! digestive system process GO:0022600 49 26 0,000 0,10679009 0,12979512 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,10679009 0,12973057 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,10679009 0,12966609 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,10679009 0,12960168 ! neural crest cell development GO:0014032 59 26 0,000 0,10679009 0,12953733 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,10679009 0,12947304 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10679009 0,12940882 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10679009 0,12934466 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10679009 0,12928057 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10679009 0,12921653 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,10679009 0,12915257 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,10679009 0,12908866 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,10679009 0,12902482 ! blastocyst development GO:0001824 50 26 0,000 0,10679009 0,12896104 ! telomere organization GO:0032200 46 26 0,000 0,10679009 0,12889732 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10679009 0,12883367 ! neural tube closure GO:0001843 58 26 0,000 0,10679009 0,12877008 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,10679009 0,12870655 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10679009 0,12864309 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11066289 0,1332427 ! embryonic pattern specification GO:0009880 49 27 0,000 0,11066289 0,13317707 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,11066289 0,1331115 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,11066289 0,13304599 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,11066289 0,13298054 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11066289 0,13291517 ! iron ion transport GO:0006826 65 27 0,000 0,11066289 0,13284985 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,11066289 0,1327846 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11066289 0,13271941 ! tube lumen formation GO:0035148 59 27 0,000 0,11066289 0,13265429 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,11066289 0,13258923 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,11066289 0,13252424 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11066289 0,13245931 ! response to toxin GO:0009636 49 27 0,000 0,11066289 0,13239444 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,11066289 0,13232964 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,11066289 0,1322649 ! leukocyte proliferation GO:0070661 59 27 0,000 0,11066289 0,13220022 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,11451902 0,13673996 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,11451902 0,13667316 ! protein amino acid acylation GO:0043543 59 28 0,000 0,11451902 0,13660642 ! vesicle docking GO:0048278 55 28 0,000 0,11451902 0,13653975 ! circadian rhythm GO:0007623 56 28 0,000 0,11451902 0,13647315 ! dendrite development GO:0016358 67 28 0,000 0,11451902 0,13640661 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11451902 0,13634013 ! sperm motility GO:0030317 37 28 0,000 0,11451902 0,13627372 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11451902 0,13620738 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11451902 0,1361411 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,11451902 0,13607488 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,11451902 0,13600873 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,11451902 0,13594264 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11451902 0,13587662 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11451902 0,13581066 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,11451902 0,13574476 ! glutathione metabolic process GO:0006749 42 28 0,000 0,11451902 0,13567893 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,11451902 0,13561316 ! lipid oxidation GO:0034440 48 28 0,000 0,11451902 0,13554746 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,11451902 0,13548182 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,11835853 0,13995638 ! translational initiation GO:0006413 66 29 0,000 0,11835853 0,13988867 ! catechol metabolic process GO:0009712 55 29 0,000 0,11835853 0,13982103 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,11835853 0,13975345 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,11835853 0,13968593 ! primary neural tube formation GO:0014020 61 29 0,000 0,11835853 0,13961848 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,11835853 0,1395511 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,11835853 0,13948378 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,11835853 0,13941653 ! somitogenesis GO:0001756 52 29 0,000 0,11835853 0,13934934 ! synaptogenesis GO:0007416 46 29 0,000 0,11835853 0,13928222 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,11835853 0,13921516 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,11835853 0,13914816 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,11835853 0,13908123 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,1221815 0,14350452 ! phenol metabolic process GO:0018958 56 30 0,000 0,1221815 0,14343556 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,1221815 0,14336667 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1221815 0,14329784 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1221815 0,14322908 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1221815 0,14316038 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1221815 0,14309175 ! acute-phase response GO:0006953 50 30 0,000 0,1221815 0,14302319 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,1221815 0,14295469 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,1221815 0,14288626 ! myofibril assembly GO:0030239 50 30 0,000 0,1221815 0,14281789 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,1221815 0,14274959 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1221815 0,14268136 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,1221815 0,14261319 ! cell fate determination GO:0001709 64 30 0,000 0,1221815 0,14254508 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,1221815 0,14247704 ! phospholipid transport GO:0015914 65 30 0,000 0,1221815 0,14240906 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,1221815 0,14234115 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1221815 0,14227331 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1221815 0,14220553 ! regulation of coagulation GO:0050818 52 30 0,000 0,1221815 0,14213781 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,125988 0,14649628 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,125988 0,14642658 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,125988 0,14635696 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,125988 0,14628739 ! regulation of innate immune response GO:0045088 57 31 0,000 0,125988 0,1462179 ! ovulation cycle process GO:0022602 55 31 0,000 0,125988 0,14614847 ! peptide transport GO:0015833 60 31 0,000 0,125988 0,14607911 ! male gonad development GO:0008584 56 31 0,000 0,125988 0,14600981 ! detection of light stimulus GO:0009583 44 31 0,000 0,125988 0,14594058 ! natural killer cell activation GO:0030101 50 31 0,000 0,125988 0,14587141 ! cofactor catabolic process GO:0051187 54 31 0,000 0,125988 0,14580231 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,125988 0,14573328 ! eye morphogenesis GO:0048592 65 31 0,000 0,125988 0,14566431 ! response to heat GO:0009408 54 31 0,000 0,125988 0,1455954 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,125988 0,14552656 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1297781 0,1498336 ! collagen metabolic process GO:0032963 49 32 0,000 0,1297781 0,14976282 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1297781 0,14969211 ! spindle organization GO:0007051 50 32 0,000 0,1297781 0,14962147 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,1297781 0,14955089 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1297781 0,14948038 ! muscle cell development GO:0055001 52 32 0,000 0,1297781 0,14940994 ! mesoderm formation GO:0001707 73 32 0,000 0,1297781 0,14933956 ! ovulation cycle GO:0042698 57 32 0,000 0,1297781 0,14926925 ! BMP signaling pathway GO:0030509 71 32 0,000 0,1297781 0,14919901 ! hindbrain development GO:0030902 65 32 0,000 0,1297781 0,14912883 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,1297781 0,14905872 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1297781 0,14898867 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,1297781 0,14891869 ! gene silencing GO:0016458 71 32 0,000 0,1297781 0,14884878 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,13355187 0,15310522 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,13355187 0,1530334 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13355187 0,15296166 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,13355187 0,15288998 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,13355187 0,15281837 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,13355187 0,15274682 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,13355187 0,15267535 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,13355187 0,15260394 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13355187 0,15253259 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,13355187 0,15246132 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,13730938 0,15667764 ! post-embryonic development GO:0009791 76 34 0,000 0,13730938 0,15660449 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,13730938 0,15653141 ! cholesterol transport GO:0030301 62 34 0,000 0,13730938 0,1564584 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,13730938 0,15638546 ! spliceosome assembly GO:0000245 75 34 0,000 0,13730938 0,15631259 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,13730938 0,15623979 ! formation of primary germ layer GO:0001704 76 34 0,000 0,13730938 0,15616705 ! cell fate specification GO:0001708 56 34 0,000 0,13730938 0,15609438 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,13730938 0,15602178 ! adult locomotory behavior GO:0008344 62 34 0,000 0,13730938 0,15594924 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,13730938 0,15587677 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,1410507 0,16004964 ! negative regulation of secretion GO:0051048 68 35 0,000 0,1410507 0,15997533 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,1410507 0,1599011 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,1410507 0,15982693 ! membrane docking GO:0022406 69 35 0,000 0,1410507 0,15975284 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,1410507 0,15967881 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,1410507 0,15960485 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,1410507 0,15953096 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,1410507 0,15945714 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,1410507 0,15938338 ! ceramide metabolic process GO:0006672 72 35 0,000 0,1410507 0,15930969 ! sterol transport GO:0015918 63 35 0,000 0,1410507 0,15923608 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,1410507 0,15916253 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,1410507 0,15908904 ! placenta development GO:0001890 53 35 0,000 0,1410507 0,15901563 ! vesicle localization GO:0051648 70 35 0,000 0,1410507 0,15894228 ! regulation of muscle development GO:0048634 82 36 0,000 0,14477591 0,16306479 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,14477591 0,16298965 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,14477591 0,16291457 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14477591 0,16283957 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,14477591 0,16276463 ! positive regulation of cell development GO:0010720 85 36 0,000 0,14477591 0,16268976 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14477591 0,16261496 ! regulation of proteolysis GO:0030162 77 36 0,000 0,14477591 0,16254023 ! aerobic respiration GO:0009060 56 36 0,000 0,14477591 0,16246557 ! embryonic organ development GO:0048568 67 36 0,000 0,14477591 0,16239097 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14477591 0,16231645 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,14848506 0,16639862 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,14848506 0,16632233 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,14848506 0,1662461 ! sister chromatid segregation GO:0000819 65 37 0,000 0,14848506 0,16616995 ! odontogenesis GO:0042476 74 37 0,000 0,14848506 0,16609386 ! actomyosin structure organization GO:0031032 68 37 0,000 0,14848506 0,16601785 ! tissue remodeling GO:0048771 78 37 0,000 0,14848506 0,1659419 ! female gonad development GO:0008585 71 37 0,000 0,14848506 0,16586602 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,14848506 0,16579022 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,15217822 0,16983618 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,15217822 0,16975863 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,15217822 0,16968115 ! organic anion transport GO:0015711 82 38 0,000 0,15217822 0,16960374 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,15217822 0,1695264 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,15217822 0,16944913 GO:0006639|acylglycerol metabolic process, ! spermatid development GO:0007286 69 38 0,000 0,15217822 0,16937194 ! glycogen metabolic process GO:0005977 63 38 0,000 0,15217822 0,16929481 ! pigment metabolic process GO:0042440 87 38 0,000 0,15217822 0,16921775 ! neural tube formation GO:0001841 79 38 0,000 0,15217822 0,16914076 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,15585548 0,17314913 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,15585548 0,17307042 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,15585548 0,17299179 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,15585548 0,17291323 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,15585548 0,17283474 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,15585548 0,17275632 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 0,000 0,15585548 0,17267797 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,15951688 0,17665446 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,15951688 0,17657442 ! learning GO:0007612 82 40 0,000 0,15951688 0,17649445 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,15951688 0,17641455 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,15951688 0,17633473 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,15951688 0,17625497 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,15951688 0,17617529 ! RNA export from nucleus GO:0006405 61 41 0,000 0,16316251 0,18012021 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,16316251 0,18003885 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,16316251 0,17995757 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,16316251 0,17987636 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,16316251 0,17979523 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,16316251 0,17971417 ! feeding behavior GO:0007631 69 41 0,000 0,16316251 0,17963318 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,16316251 0,17955226 ! mesenchymal cell development GO:0014031 94 41 0,000 0,16316251 0,17947142 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,16316251 0,17939065 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,16316251 0,17930995 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,16316251 0,17922932 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,16679243 0,18313434 ! organic ether metabolic process GO:0018904 59 42 0,000 0,16679243 0,18305207 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,16679243 0,18296987 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,16679243 0,18288775 ! regulation of protein secretion GO:0050708 77 42 0,000 0,16679243 0,1828057 ! cytokinesis GO:0000910 84 42 0,000 0,16679243 0,18272373 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,16679243 0,18264182 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,1704067 0,18651594 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1704067 0,18643241 ! regulation of tube size GO:0035150 76 43 0,000 0,1704067 0,18634896 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1704067 0,18626558 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,1704067 0,18618228 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,1704067 0,18609905 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,1704067 0,1860159 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,1704067 0,18593282 ! segmentation GO:0035282 78 43 0,000 0,1704067 0,18584981 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1704067 0,18576688 ! neuron migration GO:0001764 85 43 0,000 0,1704067 0,18568402 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,1740054 0,18952082 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,1740054 0,18943636 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,1740054 0,18935198 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,1740054 0,18926768 ! striated muscle contraction GO:0006941 85 44 0,000 0,1740054 0,18918344 ! phagocytosis GO:0006909 105 44 0,000 0,1740054 0,18909929 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1740054 0,18901521 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,17758859 0,19282174 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,17758859 0,19273608 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,17758859 0,1926505 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,17758859 0,19256499 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,17758859 0,19247956 ! female gamete generation GO:0007292 71 45 0,000 0,17758859 0,1923942 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,17758859 0,19230892 ! polyol metabolic process GO:0019751 77 45 0,000 0,17758859 0,19222372 ! developmental growth GO:0048589 88 45 0,000 0,17758859 0,19213859 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,18115633 0,19591187 ! glycolysis GO:0006096 71 46 0,000 0,18115633 0,19582519 ! leukocyte migration GO:0050900 75 46 0,000 0,18115633 0,19573858 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,18115633 0,19565204 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,18115633 0,19556559 ! neural tube development GO:0021915 91 47 0,000 0,1847087 0,19931244 ! positive regulation of defense response GO:0031349 88 48 0,000 0,18824576 0,20303946 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,18824576 0,20294986 ! endosome transport GO:0016197 127 48 0,000 0,18824576 0,20286034 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,18824576 0,20277089 ! male sex differentiation GO:0046661 93 48 0,000 0,18824576 0,20268153 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,18824576 0,20259224 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,18824576 0,20250303 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,18824576 0,2024139 ! protein homooligomerization GO:0051260 84 49 0,000 0,19176757 0,20611006 ! regulation of ion transport GO:0043269 86 50 0,000 0,1952742 0,20978666 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,1952742 0,20969444 ! regulation of ossification GO:0030278 123 50 0,000 0,1952742 0,20960231 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,1952742 0,20951026 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,1952742 0,20941829 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,1952742 0,2093264 ! viral infectious cycle GO:0019058 104 51 0,000 0,19876571 0,21297571 ! peptide metabolic process GO:0006518 80 51 0,000 0,19876571 0,21288234 ! response to temperature stimulus GO:0009266 84 51 0,000 0,19876571 0,21278906 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,20224217 0,21641595 ! Notch signaling pathway GO:0007219 111 52 0,000 0,20224217 0,2163212 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,20224217 0,21622653 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,20224217 0,21613194 ! excretion GO:0007588 87 52 0,000 0,20224217 0,21603744 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,20224217 0,21594302 ! histone modification GO:0016570 104 52 0,000 0,20224217 0,21584868 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,20224217 0,21575442 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,20224217 0,21566025 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,20224217 0,21556615 ! amino acid activation GO:0043038 98 52 0,000 0,20224217 0,21547214 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,20570365 0,21906452 ! positive regulation of growth GO:0045927 96 53 0,000 0,20570365 0,21896907 ! chromatin remodeling GO:0006338 122 53 0,000 0,20570365 0,2188737 ! vesicle organization GO:0016050 127 53 0,000 0,20570365 0,21877841 ! cartilage development GO:0051216 99 53 0,000 0,20570365 0,21868321 ! regulation of translational initiation GO:0006446 87 54 0,000 0,2091502 0,22225052 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,2091502 0,22215389 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,2091502 0,22205734 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,2091502 0,22196088 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,2091502 0,2218645 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,2091502 0,2217682 ! covalent chromatin modification GO:0016569 115 54 0,000 0,2091502 0,22167199 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,2091502 0,22157586 ! regulation of cell shape GO:0008360 142 54 0,000 0,2091502 0,22147982 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,2091502 0,22138386 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,2125819 0,22491883 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,2125819 0,22482146 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,2125819 0,22472418 ! cell recognition GO:0008037 98 55 0,000 0,2125819 0,22462698 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,2125819 0,22452986 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,2125819 0,22443283 ! glucose catabolic process GO:0006007 88 56 0,000 0,2159988 0,22794171 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,2159988 0,22784329 ! RNA elongation GO:0006354 90 56 0,000 0,2159988 0,22774496 ! chloride transport GO:0006821 102 57 0,000 0,21940097 0,23123234 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,21940097 0,23113263 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,21940097 0,231033 ! heart morphogenesis GO:0003007 105 57 0,000 0,21940097 0,23093346 ! regulation of actin filament length GO:0030832 118 58 0,000 0,22278847 0,23439803 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,22278847 0,23429713 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,22278847 0,23419631 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,22278847 0,23409558 ! gastrulation GO:0007369 122 58 0,000 0,22278847 0,23399494 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,22278847 0,23389438 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,22278847 0,23379391 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,22278847 0,23369353 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,22278847 0,23359323 ! nuclear export GO:0051168 110 59 0,000 0,22616136 0,23702798 ! establishment of organelle localization GO:0051656 122 59 0,000 0,22616136 0,23692633 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,22951972 0,24034148 ! regulation of endocytosis GO:0030100 104 60 0,000 0,22951972 0,2402385 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,22951972 0,24013562 ! adult behavior GO:0030534 104 60 0,000 0,22951972 0,24003282 ! positive regulation of secretion GO:0051047 110 61 0,000 0,23286359 0,24342565 ! regulation of cellular component size GO:0032535 125 61 0,000 0,23286359 0,24332153 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,23286359 0,24321751 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,23286359 0,24311357 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,23286359 0,24300972 ! regulation of heart contraction GO:0008016 123 61 0,000 0,23286359 0,24290595 ! camera-type eye development GO:0043010 126 61 0,000 0,23286359 0,24280228 ! proton transport GO:0015992 117 61 0,000 0,23286359 0,2426987 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,23286359 0,2425952 ! viral reproductive process GO:0022415 132 62 0,000 0,23619304 0,24595891 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,23619304 0,24585411 ! tRNA processing GO:0008033 102 62 0,000 0,23619304 0,2457494 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,23950814 0,24909254 ! regulation of mitosis GO:0007088 112 63 0,000 0,23950814 0,24898655 GO:0051783|regulation of nuclear division, ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,23950814 0,24888064 ! hydrogen transport GO:0006818 121 64 0,000 0,24280894 0,25220333 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,24280894 0,25209615 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,24280894 0,25198906 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,24609551 0,25529143 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,24609551 0,25518308 ! gonad development GO:0008406 115 66 0,000 0,2493679 0,2584666 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,25262619 0,26173273 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,25262619 0,26162178 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,25262619 0,26151092 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,25262619 0,26140016 ! secondary metabolic process GO:0019748 125 67 0,000 0,25262619 0,26128949 ! hexose catabolic process GO:0019320 113 68 0,000 0,25587042 0,26453298 ! extracellular matrix organization GO:0030198 146 68 0,000 0,25587042 0,26442108 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,25587042 0,26430927 ! viral reproduction GO:0016032 142 68 0,000 0,25587042 0,26419756 ! regulation of lipase activity GO:0060191 137 68 0,000 0,25587042 0,26408594 ! cell projection assembly GO:0030031 138 68 0,000 0,25587042 0,26397442 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,25910066 0,26719413 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,25910066 0,26708139 ! single fertilization GO:0007338 83 69 0,000 0,25910066 0,26696875 ! cell redox homeostasis GO:0045454 114 70 0,000 0,26231696 0,27016878 ! germ cell development GO:0007281 133 70 0,000 0,26231696 0,27005493 ! activation of immune response GO:0002253 120 70 0,000 0,26231696 0,26994117 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,26231696 0,26982751 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,2655194 0,27300669 ! appendage morphogenesis GO:0035107 150 72 0,000 0,26870802 0,27616899 GO:0035108|limb morphogenesis, ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,26870802 0,27605286 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,26870802 0,27593682 ! appendage development GO:0048736 151 73 0,000 0,27188289 0,27907979 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,27188289 0,27896258 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,27188289 0,27884547 ! regulation of immune effector process GO:0002697 156 73 0,000 0,27188289 0,27872845 ! acute inflammatory response GO:0002526 118 74 0,000 0,27504406 0,28185094 ! amino acid transport GO:0006865 148 74 0,000 0,27504406 0,28173277 ! organelle localization GO:0051640 155 74 0,000 0,27504406 0,28161469 ! transition metal ion transport GO:0000041 143 75 0,000 0,2781916 0,28471809 ! eye development GO:0001654 155 75 0,000 0,2781916 0,28459886 ! rhythmic process GO:0048511 142 75 0,000 0,2781916 0,28447974 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,28132557 0,28756417 ! learning or memory GO:0007611 161 76 0,000 0,28132557 0,2874439 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,28132557 0,28732373 ! regulation of blood pressure GO:0008217 134 76 0,000 0,28132557 0,28720366 ! amine catabolic process GO:0009310 136 77 0,000 0,28444601 0,290268 ! neurotransmitter transport GO:0006836 142 77 0,000 0,28444601 0,29014681 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,28444601 0,29002571 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,28444601 0,28990471 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,28444601 0,28978382 ! regulation of catabolic process GO:0009894 173 77 0,000 0,28444601 0,28966303 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,28755299 0,29270498 ! antigen processing and presentation GO:0019882 117 78 0,000 0,28755299 0,29258307 ! fertilization GO:0009566 99 78 0,000 0,28755299 0,29246126 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,28755299 0,29233956 ! blood coagulation GO:0007596 151 79 0,000 0,29064657 0,29536172 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,29064657 0,2952389 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,29064657 0,2951162 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,29064657 0,29499359 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,29064657 0,29487108 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,2937268 0,29787238 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,2937268 0,29774879 ! response to hypoxia GO:0001666 178 81 0,000 0,29679374 0,30073294 ! exocytosis GO:0006887 153 83 0,000 0,30288799 0,30678083 ! response to oxygen levels GO:0070482 183 83 0,000 0,30288799 0,30665369 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,30288799 0,30652666 ! inorganic anion transport GO:0015698 156 83 0,000 0,30288799 0,30639974 ! digestion GO:0007586 130 84 0,000 0,30591541 0,30933416 ! hemostasis GO:0007599 165 85 0,000 0,30892976 0,31225296 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,30892976 0,31212383 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,30892976 0,3119948 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,31193111 0,31489575 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,31491951 0,31778123 ! alcohol catabolic process GO:0046164 142 87 0,000 0,31491951 0,31765003 ! nucleosome assembly GO:0006334 126 87 0,000 0,31491951 0,31751893 ! cellular respiration GO:0045333 143 88 0,000 0,31789501 0,32038676 ! sensory perception of smell GO:0007608 117 88 0,000 0,31789501 0,32025464 ! chromatin assembly GO:0031497 128 88 0,000 0,31789501 0,32012264 ! tube morphogenesis GO:0035239 194 89 0,000 0,32085767 0,32297293 ! regulation of neurological system process GO:0031644 175 89 0,000 0,32085767 0,32283991 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,32380755 0,32567388 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,32966917 0,33143283 ! amine transport GO:0015837 181 93 0,000 0,33258102 0,33422272 ! vitamin metabolic process GO:0006766 153 93 0,000 0,33258102 0,3340853 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,33548031 0,33685918 ! sterol metabolic process GO:0016125 166 94 0,000 0,33548031 0,33672079 ! regulation of defense response GO:0031347 171 95 0,000 0,33836708 0,33947876 ! nucleosome organization GO:0034728 143 95 0,000 0,33836708 0,3393394 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,33836708 0,33920015 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,33836708 0,33906102 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,33836708 0,33892201 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,33836708 0,3387831 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,3441033 0,34438523 ! positive regulation of immune response GO:0050778 175 100 0,000 0,35261511 0,3527595 ! hormone metabolic process GO:0042445 171 100 0,000 0,35261511 0,35261511