pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6376-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,724E-09 6,555E-06 ! response to UV GO:0009411 104 53 5,000 7,545E-09 9,077E-06 ! protein amino acid autophosphorylation GO:0046777 141 60 5,000 1,62E-08 1,3E-05 ! negative regulation of transport GO:0051051 153 84 5,000 1,248E-07 7,508E-05 ! regulation of DNA replication GO:0006275 101 56 4,000 4,813E-07 2,316E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 5,264E-07 2,111E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 5,463E-07 1,878E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 7,008E-07 2,108E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 7,654E-07 2,046E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 7,654E-07 1,842E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 7,654E-07 1,674E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 8,966E-07 1,798E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 9,442E-07 1,748E-04 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 1,044E-06 1,794E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,119E-06 1,795E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 1,188E-06 1,787E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,675E-06 2,371E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,675E-06 2,239E-04 ! positive regulation of catabolic process GO:0009896 64 32 3,000 1,818E-06 2,302E-04 ! regulation of catabolic process GO:0009894 161 76 4,000 2,23E-06 2,682E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 2,388E-06 2,736E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,388E-06 2,612E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,277E-06 3,429E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,277E-06 3,286E-04 GO:0010829|negative regulation of glucose transport, ! cellular response to insulin stimulus GO:0032869 82 37 3,000 3,304E-06 3,18E-04 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,361E-06 4,036E-04 GO:0050927|positive regulation of positive chemotaxis, ! response to X-ray GO:0010165 25 13 2,000 5,658E-06 5,042E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 6,046E-06 5,195E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 6,097E-06 5,058E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 7,187E-06 5,764E-04 ! response to gamma radiation GO:0010332 28 14 2,000 7,187E-06 5,578E-04 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 7,433E-06 5,589E-04 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 8,011E-06 5,841E-04 ! response to insulin stimulus GO:0032868 95 46 3,000 8,011E-06 5,669E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 8,966E-06 6,164E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 2,000 1,335E-05 8,92E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,335E-05 8,679E-04 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,335E-05 8,451E-04 ! regulation of protein catabolic process GO:0042176 116 55 3,000 1,643E-05 1,014E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 1,895E-05 1,14E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,224E-05 1,305E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,224E-05 1,274E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,224E-05 1,245E-03 GO:0010827|regulation of glucose transport, ! response to peptide hormone stimulus GO:0043434 122 61 3,000 2,483E-05 1,358E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,59E-05 1,385E-03 ! cell aging GO:0007569 44 21 2,000 2,59E-05 1,355E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,59E-05 1,326E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,59E-05 1,298E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 2,993E-05 1,469E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 2,993E-05 1,44E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,993E-05 1,412E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 2,993E-05 1,385E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,993E-05 1,359E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 3,435E-05 1,53E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 3,601E-05 1,575E-03 ! lung development GO:0030324 144 67 3,000 3,601E-05 1,547E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 3,818E-05 1,612E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,918E-05 1,625E-03 ! regulation of behavior GO:0050795 43 24 2,000 3,918E-05 1,598E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,918E-05 1,571E-03 ! respiratory tube development GO:0030323 150 70 3,000 4,281E-05 1,688E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 4,443E-05 1,724E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 4,443E-05 1,697E-03 ! receptor metabolic process GO:0043112 46 25 2,000 4,443E-05 1,67E-03 ! interaction with host GO:0051701 62 25 2,000 4,443E-05 1,645E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 4,443E-05 1,62E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 4,783E-05 1,718E-03 ! respiratory system development GO:0060541 153 72 3,000 4,783E-05 1,692E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 6,291E-05 2,194E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 6,884E-05 2,366E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 7,003E-05 2,373E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 7,464E-05 2,494E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 7,464E-05 2,46E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 7,464E-05 2,427E-03 ! microvillus organization GO:0032528 7 5 1,000 7,464E-05 2,394E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 7,464E-05 2,363E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 7,464E-05 2,332E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 7,464E-05 2,302E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 7,464E-05 2,273E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 7,464E-05 2,245E-03 GO:0051930|regulation of sensory perception of pain, ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 7,591E-05 2,255E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 3,000 7,964E-05 2,337E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 9,449E-05 2,739E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 9,449E-05 2,706E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,037E-04 2,936E-03 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 2,000 1,037E-04 2,902E-03 ! male meiosis GO:0007140 7 6 1,000 1,118E-04 3,091E-03 ! male sex determination GO:0030238 15 6 1,000 1,118E-04 3,055E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,118E-04 3,021E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 1,118E-04 2,988E-03 ! protein targeting to lysosome GO:0006622 10 6 1,000 1,118E-04 2,955E-03 ! receptor internalization GO:0031623 10 6 1,000 1,118E-04 2,923E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,118E-04 2,891E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,135E-04 2,906E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,239E-04 3,139E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,562E-04 3,914E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 1,562E-04 3,874E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,562E-04 3,834E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,562E-04 3,795E-03 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 1,562E-04 3,758E-03 GO:0031958|corticosteroid receptor signaling pathway, ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 1,562E-04 3,72E-03 ! centrosome duplication GO:0051298 13 7 1,000 1,562E-04 3,684E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,562E-04 3,648E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,562E-04 3,613E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,562E-04 3,579E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,562E-04 3,545E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,562E-04 3,512E-03 ! positive regulation of ATPase activity GO:0032781 11 7 1,000 1,562E-04 3,479E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,588E-04 3,505E-03 ! mammary gland development GO:0030879 86 39 2,000 1,717E-04 3,755E-03 ! cell cycle arrest GO:0007050 213 100 3,000 1,719E-04 3,727E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,079E-04 4,465E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,079E-04 4,426E-03 ! ER overload response GO:0006983 12 8 1,000 2,079E-04 4,387E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 2,079E-04 4,349E-03 ! protein targeting to vacuole GO:0006623 12 8 1,000 2,079E-04 4,311E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,079E-04 4,274E-03 ! blastocyst growth GO:0001832 19 8 1,000 2,079E-04 4,238E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,144E-04 4,335E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,3E-04 4,612E-03 ! double-strand break repair GO:0006302 81 44 2,000 2,464E-04 4,899E-03 ! leukocyte migration GO:0050900 68 45 2,000 2,634E-04 5,195E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,668E-04 5,218E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,668E-04 5,176E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,668E-04 5,135E-03 ! receptor clustering GO:0043113 18 9 1,000 2,668E-04 5,094E-03 ! motor axon guidance GO:0008045 16 9 1,000 2,668E-04 5,054E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,668E-04 5,014E-03 ! induction of an organ GO:0001759 14 9 1,000 2,668E-04 4,976E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,813E-04 5,205E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,813E-04 5,166E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 2,998E-04 5,465E-03 ! endosome transport GO:0016197 108 47 2,000 2,998E-04 5,424E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,192E-04 5,731E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,192E-04 5,689E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,192E-04 5,647E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,329E-04 5,846E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,329E-04 5,803E-03 ! pathogenesis GO:0009405 13 10 1,000 3,329E-04 5,762E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 3,329E-04 5,72E-03 ! regulation of sodium ion transport GO:0002028 21 10 1,000 3,329E-04 5,68E-03 ! multicellular organism growth GO:0035264 18 10 1,000 3,329E-04 5,64E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,329E-04 5,6E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 3,329E-04 5,562E-03 ! localization within membrane GO:0051668 20 10 1,000 3,329E-04 5,523E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 3,393E-04 5,592E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,82E-04 6,253E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 2,000 4,046E-04 6,578E-03 ! cartilage development GO:0051216 90 52 2,000 4,046E-04 6,534E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,061E-04 6,514E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,061E-04 6,471E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 4,061E-04 6,428E-03 ! nitric oxide metabolic process GO:0046209 15 11 1,000 4,061E-04 6,386E-03 GO:0006809|nitric oxide biosynthetic process, ! oocyte differentiation GO:0009994 18 11 1,000 4,061E-04 6,345E-03 ! developmental induction GO:0031128 19 11 1,000 4,061E-04 6,304E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 4,061E-04 6,263E-03 ! aging GO:0007568 103 55 2,000 4,775E-04 7,317E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,865E-04 7,408E-03 ! virus-host interaction GO:0019048 29 12 1,000 4,865E-04 7,361E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 4,865E-04 7,315E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 4,865E-04 7,27E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 4,865E-04 7,225E-03 ! L-glutamate transport GO:0015813 22 12 1,000 4,865E-04 7,18E-03 GO:0015800|acidic amino acid transport, ! histone acetylation GO:0016573 26 12 1,000 4,865E-04 7,137E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,865E-04 7,093E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,865E-04 7,051E-03 GO:0042130|negative regulation of T cell proliferation, ! nucleotide-excision repair GO:0006289 83 56 2,000 5,035E-04 7,254E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 5,304E-04 7,596E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 5,739E-04 8,17E-03 GO:0000725|recombinational repair, ! cell-cell junction assembly GO:0007043 27 13 1,000 5,739E-04 8,122E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 5,739E-04 8,074E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 5,739E-04 8,027E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 5,739E-04 7,981E-03 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 5,739E-04 7,935E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 5,739E-04 7,89E-03 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 6,167E-04 8,43E-03 ! regulation of heart contraction GO:0008016 110 60 2,000 6,167E-04 8,382E-03 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 6,167E-04 8,335E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 6,683E-04 8,983E-03 ! regulation of S phase GO:0033261 23 14 1,000 6,683E-04 8,933E-03 ! regulation of mRNA processing GO:0050684 24 14 1,000 6,683E-04 8,884E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 6,683E-04 8,835E-03 ! male genitalia development GO:0030539 24 14 1,000 6,683E-04 8,787E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 6,683E-04 8,739E-03 ! viral reproductive process GO:0022415 126 62 2,000 6,788E-04 8,829E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 7,698E-04 9,957E-03 ! G1/S transition checkpoint GO:0031575 40 15 1,000 7,698E-04 9,904E-03 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 7,698E-04 9,851E-03 ! regulation of ATPase activity GO:0043462 21 15 1,000 7,698E-04 9,799E-03 ! negative regulation of cell growth GO:0030308 132 67 2,000 8,514E-04 0,01078108 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 8,781E-04 0,01106187 ! dicarboxylic acid transport GO:0006835 38 16 1,000 8,781E-04 0,01100425 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 8,781E-04 0,01094724 ! startle response GO:0001964 28 16 1,000 8,781E-04 0,01089081 ! lysosomal transport GO:0007041 26 16 1,000 8,781E-04 0,01083496 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 8,781E-04 0,01077968 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 8,781E-04 0,01072496 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 8,781E-04 0,01067079 ! viral reproduction GO:0016032 134 68 2,000 8,889E-04 0,01074728 ! negative regulation of cell size GO:0045792 134 69 2,000 9,275E-04 0,01115749 ! signal complex assembly GO:0007172 41 17 1,000 9,935E-04 0,01189176 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 9,935E-04 0,01183289 ! genitalia development GO:0048806 30 17 1,000 9,935E-04 0,0117746 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,049E-03 0,01237779 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,116E-03 0,01309374 ! negative regulation of ion transport GO:0043271 24 18 1,000 1,116E-03 0,01303018 ! centrosome cycle GO:0007098 25 18 1,000 1,116E-03 0,01296723 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 1,116E-03 0,01290489 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,116E-03 0,01284314 ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,136E-03 0,01301766 GO:0090046|regulation of transcription regulator activity, ! development of primary sexual characteristics GO:0045137 124 76 2,000 1,227E-03 0,01399492 ! lipid phosphorylation GO:0046834 35 19 1,000 1,245E-03 0,01412568 ! mitotic chromosome condensation GO:0007076 34 19 1,000 1,245E-03 0,01405937 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,245E-03 0,01399367 ! pigmentation during development GO:0048066 41 19 1,000 1,245E-03 0,01392858 ! neuromuscular junction development GO:0007528 34 19 1,000 1,245E-03 0,0138641 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 1,245E-03 0,01380021 ! cell-cell junction organization GO:0045216 35 19 1,000 1,245E-03 0,0137369 ! protein oligomerization GO:0051259 139 78 2,000 1,323E-03 0,01453392 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,38E-03 0,01509744 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,38E-03 0,01502913 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,38E-03 0,01496143 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,38E-03 0,01489434 ! cellular response to starvation GO:0009267 33 20 1,000 1,38E-03 0,01482785 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,38E-03 0,01476194 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,38E-03 0,01469663 ! oogenesis GO:0048477 36 21 1,000 1,523E-03 0,01614319 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,523E-03 0,01607238 ! negative regulation of growth GO:0045926 155 84 2,000 1,637E-03 0,01720326 ! vacuolar transport GO:0007034 36 22 1,000 1,672E-03 0,01749458 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,672E-03 0,01741885 ! protein stabilization GO:0050821 39 22 1,000 1,672E-03 0,01734376 ! regulation of protein transport GO:0051223 154 87 2,000 1,811E-03 0,01869738 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,828E-03 0,01879956 ! sex determination GO:0007530 47 23 1,000 1,828E-03 0,01871956 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,828E-03 0,01864024 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,828E-03 0,01856159 ! positive regulation of protein modification process GO:0031401 136 88 2,000 1,871E-03 0,01891321 ! regulation of DNA binding GO:0051101 155 88 2,000 1,871E-03 0,01883407 ! gland development GO:0048732 206 88 2,000 1,871E-03 0,0187556 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,991E-03 0,01987737 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,991E-03 0,01979523 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,991E-03 0,01971377 ! sex differentiation GO:0007548 145 90 2,000 1,995E-03 0,01967212 ! regulation of defense response GO:0031347 149 92 2,000 2,124E-03 0,02086007 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,16E-03 0,02112891 ! myelination GO:0042552 45 25 1,000 2,16E-03 0,02104337 ! chromosome condensation GO:0030261 45 25 1,000 2,16E-03 0,02095851 ! response to starvation GO:0042594 42 25 1,000 2,16E-03 0,02087434 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,16E-03 0,02079085 ! negative regulation of cell development GO:0010721 73 25 1,000 2,16E-03 0,02070801 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 2,16E-03 0,02062584 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,16E-03 0,02054431 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 2,327E-03 0,02204642 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,336E-03 0,02204237 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 2,336E-03 0,02195627 ! microtubule organizing center organization GO:0031023 39 26 1,000 2,336E-03 0,02187083 GO:0051297|centrosome organization, ! blastocyst development GO:0001824 49 26 1,000 2,336E-03 0,02178606 ! protein ubiquitination GO:0016567 217 97 2,000 2,469E-03 0,02293979 ! regulation of protein localization GO:0032880 176 97 2,000 2,469E-03 0,02285156 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,519E-03 0,02321699 ! protein amino acid acylation GO:0043543 55 27 1,000 2,519E-03 0,02312838 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,519E-03 0,02304044 ! response to toxin GO:0009636 47 27 1,000 2,519E-03 0,02295317 ! base-excision repair GO:0006284 41 27 1,000 2,519E-03 0,02286655 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,519E-03 0,02278058 ! interphase GO:0051325 213 98 2,000 2,542E-03 0,0229099 ! skeletal muscle tissue development GO:0007519 186 99 2,000 2,617E-03 0,02349127 GO:0060538|skeletal muscle organ development, ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,707E-03 0,02421605 ! regulation of pH GO:0006885 43 29 1,000 2,903E-03 0,02586728 ! response to organic cyclic substance GO:0014070 55 29 1,000 2,903E-03 0,02577183 ! tissue homeostasis GO:0001894 48 29 1,000 2,903E-03 0,02567708 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 78 30 1,000 3,105E-03 0,0273615 ! ensheathment of neurons GO:0007272 57 30 1,000 3,105E-03 0,02726164 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,105E-03 0,02716251 ! regulation of B cell activation GO:0050864 50 30 1,000 3,105E-03 0,02706409 ! response to heat GO:0009408 50 30 1,000 3,105E-03 0,02696639 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,313E-03 0,02867123 GO:0043433|negative regulation of transcription factor activity, ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,527E-03 0,03041871 ! peripheral nervous system development GO:0007422 64 32 1,000 3,527E-03 0,03031007 ! DNA damage checkpoint GO:0000077 71 33 1,000 3,748E-03 0,03209344 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 3,748E-03 0,03197963 ! cell fate specification GO:0001708 52 33 1,000 3,748E-03 0,03186663 ! adult locomotory behavior GO:0008344 59 33 1,000 3,748E-03 0,03175442 ! xenobiotic metabolic process GO:0006805 51 34 1,000 3,975E-03 0,03356078 ! odontogenesis GO:0042476 66 35 1,000 4,209E-03 0,03540712 ! female gonad development GO:0008585 58 35 1,000 4,209E-03 0,03528375 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 4,209E-03 0,03516123 ! calcium-mediated signaling GO:0019722 62 35 1,000 4,209E-03 0,03503957 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 4,448E-03 0,03690693 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 4,448E-03 0,0367801 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 4,448E-03 0,03665414 ! maintenance of protein location in cell GO:0032507 86 36 1,000 4,448E-03 0,03652904 ! DNA integrity checkpoint GO:0031570 75 36 1,000 4,448E-03 0,03640479 ! negative regulation of cell activation GO:0050866 65 36 1,000 4,448E-03 0,03628139 ! sister chromatid segregation GO:0000819 58 37 1,000 4,694E-03 0,03815696 ! organic anion transport GO:0015711 68 37 1,000 4,694E-03 0,03802849 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 4,694E-03 0,03790087 ! negative regulation of DNA binding GO:0043392 68 37 1,000 4,694E-03 0,03777411 ! regulation of protein stability GO:0031647 73 37 1,000 4,694E-03 0,0376482 ! regulation of metal ion transport GO:0010959 63 38 1,000 4,946E-03 0,03953722 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 4,946E-03 0,0394063 ! carbohydrate homeostasis GO:0033500 53 38 1,000 4,946E-03 0,03927625 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 4,946E-03 0,03914705 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,946E-03 0,0390187 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! development of primary male sexual characteristics GO:0046546 66 39 1,000 5,204E-03 0,04092044 ! segmentation GO:0035282 67 39 1,000 5,204E-03 0,04078715 ! regulation of action potential in neuron GO:0019228 73 39 1,000 5,204E-03 0,04065472 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 5,204E-03 0,04052316 ! negative regulation of binding GO:0051100 72 40 1,000 5,469E-03 0,04244268 ! maintenance of protein location GO:0045185 91 40 1,000 5,469E-03 0,04230621 ! cytokinesis GO:0000910 72 40 1,000 5,469E-03 0,04217061 ! regulation of T cell proliferation GO:0042129 71 41 1,000 5,739E-03 0,04411293 ! T cell differentiation GO:0030217 81 41 1,000 5,739E-03 0,04397245 ! regulation of T cell differentiation GO:0045580 70 41 1,000 5,739E-03 0,04383285 ! female gamete generation GO:0007292 61 41 1,000 5,739E-03 0,04369414 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 6,015E-03 0,04565276 GO:0090047|positive regulation of transcription regulator activity, ! receptor-mediated endocytosis GO:0006898 88 43 1,000 6,297E-03 0,04764426 ! male sex differentiation GO:0046661 76 44 1,000 6,585E-03 0,04966809 ! B cell differentiation GO:0030183 107 44 1,000 6,585E-03 0,04951287 ! developmental growth GO:0048589 82 44 1,000 6,585E-03 0,04935863 ! maintenance of location in cell GO:0051651 97 44 1,000 6,585E-03 0,04920534 ! cell growth GO:0016049 84 45 1,000 6,879E-03 0,05124327 ! pigmentation GO:0043473 100 46 1,000 7,179E-03 0,05331223 ! positive regulation of protein transport GO:0051222 72 46 1,000 7,179E-03 0,05314819 ! response to calcium ion GO:0051592 81 47 1,000 7,485E-03 0,0552417 ! positive regulation of DNA binding GO:0043388 73 47 1,000 7,485E-03 0,05507277 ! mitochondrial transport GO:0006839 82 48 1,000 7,797E-03 0,05719023 ! activation of caspase activity GO:0006919 84 48 1,000 7,797E-03 0,0570164 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 7,797E-03 0,05684363 ! regulation of action potential GO:0001508 95 49 1,000 8,114E-03 0,0589785 ! regulation of ion transport GO:0043269 77 49 1,000 8,114E-03 0,05880086 ! peptide metabolic process GO:0006518 76 49 1,000 8,114E-03 0,05862428 ! response to temperature stimulus GO:0009266 76 49 1,000 8,114E-03 0,05844876 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 8,114E-03 0,05827428 ! neuromuscular process GO:0050905 99 50 1,000 8,437E-03 0,06041422 ! histone modification GO:0016570 91 50 1,000 8,437E-03 0,06023495 ! negative regulation of immune system process GO:0002683 95 50 1,000 8,437E-03 0,06005674 ! positive regulation of binding GO:0051099 78 51 1,000 8,766E-03 0,06221298 ! response to estrogen stimulus GO:0043627 93 51 1,000 8,766E-03 0,06203 ! regulation of angiogenesis GO:0045765 114 52 1,000 9,1E-03 0,06420782 ! positive regulation of growth GO:0045927 90 52 1,000 9,1E-03 0,06402008 ! covalent chromatin modification GO:0016569 101 52 1,000 9,1E-03 0,06383343 ! synapse organization GO:0050808 85 52 1,000 9,1E-03 0,06364787 ! regulation of translational initiation GO:0006446 82 53 1,000 9,44E-03 0,06583508 ! cell maturation GO:0048469 100 53 1,000 9,44E-03 0,0656448 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 9,44E-03 0,06545563 ! activation of phospholipase C activity GO:0007202 103 54 1,000 9,786E-03 0,06765755 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01013714 0,06988527 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01013714 0,0696856 ! heart morphogenesis GO:0003007 97 55 1,000 0,01013714 0,06948706 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01049394 0,07172847 ! muscle fiber development GO:0048747 112 57 1,000 0,01085625 0,07399473 ! lipid modification GO:0030258 97 57 1,000 0,01085625 0,07378571 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01085625 0,07357786 ! maintenance of location GO:0051235 118 57 1,000 0,01085625 0,07337118 ! adult behavior GO:0030534 99 58 1,000 0,01122404 0,07564435 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01122404 0,07543305 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01159727 0,0777243 ! gonad development GO:0008406 98 62 1,000 0,0127493 0,08520782 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01314399 0,08760231 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01370476 0,09108741 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01370476 0,09083648 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01370476 0,09058693 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01370476 0,09033875 ! neuron fate determination GO:0048664 7 5 0,000 0,01370476 0,09009192 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01370476 0,08984644 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01370476 0,08960229 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01370476 0,08935947 ! polyol transport GO:0015791 12 5 0,000 0,01370476 0,08911796 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01370476 0,08887774 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01370476 0,08863883 ! response to superoxide GO:0000303 10 5 0,000 0,01370476 0,08840119 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01370476 0,08816482 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01370476 0,08792972 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01370476 0,08769586 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01370476 0,08746325 ! female meiosis GO:0007143 7 5 0,000 0,01370476 0,08723186 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01370476 0,0870017 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01370476 0,08677275 ! cobalt ion transport GO:0006824 11 5 0,000 0,01370476 0,086545 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01370476 0,08631844 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01370476 0,08609306 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01370476 0,08586886 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01370476 0,08564583 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01370476 0,08542395 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01370476 0,08520321 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01370476 0,08498362 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01370476 0,08476515 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01370476 0,0845478 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01370476 0,08433157 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01370476 0,08411644 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01370476 0,0839024 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01370476 0,08368945 ! negative chemotaxis GO:0050919 14 5 0,000 0,01370476 0,08347758 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01370476 0,08326678 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01370476 0,08305704 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01370476 0,08284835 ! behavioral response to pain GO:0048266 9 5 0,000 0,01370476 0,08264071 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01370476 0,08243411 ! Notch receptor processing GO:0007220 8 5 0,000 0,01370476 0,08222854 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01370476 0,08202399 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01370476 0,08182046 ! micturition GO:0060073 9 5 0,000 0,01370476 0,08161793 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01370476 0,0814164 ! copulation GO:0007620 9 5 0,000 0,01370476 0,08121587 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01370476 0,08101632 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01370476 0,08081775 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01370476 0,08062015 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01370476 0,08042352 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01370476 0,08022784 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01370476 0,08003312 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01370476 0,07983933 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01370476 0,07964648 ! grooming behavior GO:0007625 6 5 0,000 0,01370476 0,07945456 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01370476 0,07926357 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01370476 0,07907349 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01370476 0,07888431 ! response to protozoan GO:0001562 10 5 0,000 0,01370476 0,07869605 ! lymph vessel development GO:0001945 10 5 0,000 0,01370476 0,07850867 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01370476 0,07832219 ! endochondral ossification GO:0001958 16 5 0,000 0,01370476 0,0781366 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01370476 0,07795188 ! parathyroid gland development GO:0060017 13 5 0,000 0,01370476 0,07776803 ! anagen GO:0042640 6 5 0,000 0,01370476 0,07758504 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01370476 0,07740292 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01370476 0,07722165 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01370476 0,07704122 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01370476 0,07686164 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01370476 0,07668289 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01370476 0,07650497 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01370476 0,07632788 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01370476 0,0761516 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01370476 0,07597614 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01370476 0,07580148 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01370476 0,07562762 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01370476 0,07545456 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01370476 0,07528229 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01370476 0,0751108 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01370476 0,0749401 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01370476 0,07477017 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01370476 0,074601 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01370476 0,0744326 ! histidine catabolic process GO:0006548 6 5 0,000 0,01370476 0,07426496 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01370476 0,07409808 ! valine metabolic process GO:0006573 10 5 0,000 0,01370476 0,07393194 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01370476 0,07376654 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01370476 0,07360188 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01370476 0,07343796 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01370476 0,07327476 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01370476 0,07311229 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01370476 0,07295054 ! polyol catabolic process GO:0046174 7 5 0,000 0,01370476 0,0727895 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01370476 0,07262917 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01370476 0,07246955 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01370476 0,07231062 ! muscle cell migration GO:0014812 8 5 0,000 0,01370476 0,07215239 ! mitochondrial fission GO:0000266 8 5 0,000 0,01370476 0,07199485 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01370476 0,071838 ! mRNA transcription GO:0009299 9 5 0,000 0,01370476 0,07168183 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01370476 0,07152634 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01370476 0,07137152 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01370476 0,07121737 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01370476 0,07106389 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01370476 0,07091106 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01370476 0,07075889 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01370476 0,07060737 ! response to food GO:0032094 6 5 0,000 0,01370476 0,0704565 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01370476 0,07030628 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01370476 0,07015669 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01370476 0,07000774 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01370476 0,06985941 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01370476 0,06971172 ! forebrain neuron development GO:0021884 13 5 0,000 0,01370476 0,06956465 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01370476 0,0694182 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01370476 0,06927236 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01370476 0,06912713 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01370476 0,06898252 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01370476 0,0688385 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01370476 0,06869509 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01370476 0,06855227 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01370476 0,06841005 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01370476 0,06826841 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01370476 0,06812736 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01370476 0,06798689 ! basic amino acid transport GO:0015802 11 5 0,000 0,01370476 0,067847 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01370476 0,06770769 ! depyrimidination GO:0045008 10 5 0,000 0,01370476 0,06756894 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01370476 0,06743076 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01370476 0,06729315 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01370476 0,0671561 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01370476 0,0670196 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01370476 0,06688366 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01370476 0,06674827 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01370476 0,06661342 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01370476 0,06647912 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01370476 0,06634536 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01370476 0,06621214 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01370476 0,06607945 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01370476 0,06594729 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01370476 0,06581566 ! response to arsenic GO:0046685 10 5 0,000 0,01370476 0,06568455 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01370476 0,06555396 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01370476 0,0654239 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01370476 0,06529434 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01370476 0,0651653 ! response to cadmium ion GO:0046686 7 5 0,000 0,01370476 0,06503677 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01370476 0,06490875 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01370476 0,06478122 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01370476 0,0646542 ! decidualization GO:0046697 11 5 0,000 0,01370476 0,06452768 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01370476 0,06440165 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01370476 0,06427611 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01370476 0,06415106 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01370476 0,06402649 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01370476 0,06390241 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01370476 0,06377881 ! neural tube patterning GO:0021532 7 5 0,000 0,01370476 0,06365568 ! embryonic cleavage GO:0040016 6 5 0,000 0,01370476 0,06353303 ! peroxisome fission GO:0016559 5 5 0,000 0,01370476 0,06341085 ! histone demethylation GO:0016577 10 5 0,000 0,01370476 0,06328914 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01370476 0,0631679 ! mitotic recombination GO:0006312 9 5 0,000 0,01370476 0,06304712 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01370476 0,0629268 ! metaphase plate congression GO:0051310 7 5 0,000 0,01370476 0,06280694 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01370476 0,06268753 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01370476 0,06256858 ! enteric nervous system development GO:0048484 8 5 0,000 0,01370476 0,06245008 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01370476 0,06233203 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01370476 0,06221442 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01370476 0,06209726 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01370476 0,06198053 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01370476 0,06186425 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01370476 0,0617484 ! plasminogen activation GO:0031639 5 5 0,000 0,01370476 0,06163298 ! B cell homeostasis GO:0001782 13 5 0,000 0,01370476 0,06151799 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01370476 0,06140343 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01370476 0,0612893 ! metaphase GO:0051323 8 5 0,000 0,01370476 0,06117559 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01370476 0,0610623 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01370476 0,06094943 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01370476 0,06083698 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01370476 0,06072494 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01370476 0,06061332 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01370476 0,0605021 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01370476 0,06039129 ! response to redox state GO:0051775 5 5 0,000 0,01370476 0,06028088 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01370476 0,06017088 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01370476 0,06006128 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01370476 0,05995208 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01370476 0,05984327 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01370476 0,05973486 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01370476 0,05962684 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01370476 0,05951921 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01370476 0,05941197 ! striatum development GO:0021756 9 5 0,000 0,01370476 0,05930511 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01370476 0,05919864 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01370476 0,05909255 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01370476 0,05898684 ! glial cell migration GO:0008347 11 5 0,000 0,01370476 0,05888151 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01370476 0,05877655 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01370476 0,05867196 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01370476 0,05856775 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01370476 0,05846391 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01370476 0,05836043 ! neuroprotection GO:0043526 6 5 0,000 0,01370476 0,05825732 ! neural plate development GO:0001840 8 5 0,000 0,01370476 0,05815457 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01370476 0,05805219 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01370476 0,05795016 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01370476 0,0578485 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01370476 0,05774719 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01370476 0,05764623 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01370476 0,05754563 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01370476 0,05744537 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01370476 0,05734547 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01370476 0,05724591 ! spindle assembly GO:0051225 6 5 0,000 0,01370476 0,0571467 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01370476 0,05704783 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01370476 0,0569493 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01370476 0,05685111 ! drug metabolic process GO:0017144 6 5 0,000 0,01370476 0,05675326 ! stem cell division GO:0017145 11 5 0,000 0,01370476 0,05665574 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01370476 0,05655856 ! organ regeneration GO:0031100 7 5 0,000 0,01370476 0,05646172 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01370476 0,0563652 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01370476 0,05626902 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01370476 0,05617316 ! germ cell development GO:0007281 118 65 1,000 0,01394918 0,05707778 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01435963 0,05865751 ! actin filament organization GO:0007015 148 66 1,000 0,01435963 0,05855809 ! extracellular matrix organization GO:0030198 133 66 1,000 0,01435963 0,05845901 ! developmental maturation GO:0021700 116 66 1,000 0,01435963 0,05836026 ! cell projection assembly GO:0030031 120 66 1,000 0,01435963 0,05826184 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01477527 0,0598473 ! chromosome segregation GO:0007059 113 67 1,000 0,01477527 0,05974672 ! amino acid transport GO:0006865 125 68 1,000 0,01519607 0,0613452 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01519607 0,06124245 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01519607 0,06114003 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,015622 0,06274879 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,015622 0,06264421 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01642336 0,06574808 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01642336 0,06563887 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01642336 0,06553001 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01642336 0,06542152 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01642336 0,06531338 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01642336 0,06520561 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01642336 0,06509818 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01642336 0,06499111 ! sleep GO:0030431 13 6 0,000 0,01642336 0,0648844 ! response to oxygen radical GO:0000305 11 6 0,000 0,01642336 0,06477803 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01642336 0,06467201 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01642336 0,06456633 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01642336 0,06446101 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01642336 0,06435602 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01642336 0,06425138 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01642336 0,06414707 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01642336 0,06404311 ! forebrain regionalization GO:0021871 8 6 0,000 0,01642336 0,06393948 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01642336 0,06383618 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01642336 0,06373322 ! response to zinc ion GO:0010043 9 6 0,000 0,01642336 0,06363059 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01642336 0,06352829 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01642336 0,06342632 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01642336 0,06332467 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01642336 0,06322335 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01642336 0,06312236 ! malate metabolic process GO:0006108 11 6 0,000 0,01642336 0,06302169 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01642336 0,06292133 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01642336 0,0628213 ! protein refolding GO:0042026 15 6 0,000 0,01642336 0,06272158 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01642336 0,06262218 ! opsonization GO:0008228 8 6 0,000 0,01642336 0,0625231 ! mating behavior GO:0007617 7 6 0,000 0,01642336 0,06242432 ! neuron remodeling GO:0016322 15 6 0,000 0,01642336 0,06232586 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01642336 0,06222771 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01642336 0,06212987 ! equilibrioception GO:0050957 14 6 0,000 0,01642336 0,06203233 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01642336 0,0619351 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01642336 0,06183818 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01642336 0,06174156 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01642336 0,06164524 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01642336 0,06154922 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01642336 0,06145349 ! toxin metabolic process GO:0009404 11 6 0,000 0,01642336 0,06135807 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01642336 0,06126294 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01642336 0,06116811 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01642336 0,06107357 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01642336 0,06097932 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01642336 0,06088536 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01642336 0,06079169 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01642336 0,06069831 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01642336 0,06060521 ! thymic T cell selection GO:0045061 12 6 0,000 0,01642336 0,0605124 ! protein lipoylation GO:0009249 10 6 0,000 0,01642336 0,06041987 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01642336 0,06032763 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01642336 0,06023567 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01642336 0,06014398 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01642336 0,06005258 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01642336 0,05996145 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01642336 0,0598706 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01642336 0,05978003 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01642336 0,05968972 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01642336 0,05959969 ! hyperosmotic response GO:0006972 9 6 0,000 0,01642336 0,05950993 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01642336 0,05942045 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01642336 0,05933123 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01642336 0,05924227 ! urea metabolic process GO:0019627 7 6 0,000 0,01642336 0,05915359 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01642336 0,05906517 ! neutrophil activation GO:0042119 8 6 0,000 0,01642336 0,05897701 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01642336 0,05888912 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01642336 0,05880148 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01642336 0,05871411 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01642336 0,058627 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01642336 0,05854014 ! neuron apoptosis GO:0051402 9 6 0,000 0,01642336 0,05845355 ! nucleoside salvage GO:0043174 9 6 0,000 0,01642336 0,0583672 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01642336 0,05828112 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01642336 0,05819528 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01642336 0,0581097 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01642336 0,05802437 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01642336 0,05793929 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01642336 0,05785446 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01642336 0,05776988 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01642336 0,05768554 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01642336 0,05760145 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01642336 0,05751761 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01642336 0,05743401 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01642336 0,05735065 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01642336 0,05726753 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01642336 0,05718466 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01642336 0,05710202 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01642336 0,05701962 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01642336 0,05693746 ! neural nucleus development GO:0048857 14 6 0,000 0,01642336 0,05685553 ! astrocyte development GO:0014002 15 6 0,000 0,01642336 0,05677385 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01642336 0,05669239 ! interaction with symbiont GO:0051702 13 6 0,000 0,01642336 0,05661117 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01642336 0,05653018 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01642336 0,05644942 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01642336 0,0563689 ! response to copper ion GO:0046688 10 6 0,000 0,01642336 0,0562886 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01642336 0,05620853 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01642336 0,05612869 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01642336 0,05604907 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01642336 0,05596968 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01642336 0,05589052 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01642336 0,05581158 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01642336 0,05573286 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01642336 0,05565436 ! hair follicle maturation GO:0048820 7 6 0,000 0,01642336 0,05557609 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01642336 0,05549803 ! Schwann cell development GO:0014044 15 6 0,000 0,01642336 0,05542019 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01642336 0,05534257 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01642336 0,05526517 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01642336 0,05518798 ! subpallium development GO:0021544 10 6 0,000 0,01642336 0,05511101 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01642336 0,05503426 ! histone ubiquitination GO:0016574 8 6 0,000 0,01642336 0,05495771 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01642336 0,05488138 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01642336 0,05480527 ! G2 phase GO:0051319 16 6 0,000 0,01642336 0,05472936 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01642336 0,05465366 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01642336 0,05457817 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01642336 0,05450289 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01642336 0,05442782 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01642336 0,05435295 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01642336 0,05427829 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01642336 0,05420384 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01642336 0,05412958 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01642336 0,05405554 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01642336 0,05398169 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01642336 0,05390804 ! protein deubiquitination GO:0016579 14 6 0,000 0,01642336 0,0538346 ! protein destabilization GO:0031648 9 6 0,000 0,01642336 0,05376136 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01642336 0,05368831 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01642336 0,05361546 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01642336 0,05354281 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01642336 0,05347036 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01642336 0,0533981 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01642336 0,05332604 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01642336 0,05325417 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01642336 0,0531825 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01642336 0,05311102 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01642336 0,05303973 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01642336 0,05296863 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01642336 0,05289772 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01642336 0,052827 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01642336 0,05275647 ! catecholamine transport GO:0051937 9 6 0,000 0,01642336 0,05268613 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01642336 0,05261597 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01642336 0,05254601 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01642336 0,05247622 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01642336 0,05240663 ! maternal placenta development GO:0001893 12 6 0,000 0,01642336 0,05233721 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01642336 0,05226799 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01642336 0,05219894 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01642336 0,05213007 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01642336 0,05206139 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01642336 0,05199289 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01642336 0,05192457 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01642336 0,05185643 ! reproductive structure development GO:0048608 113 71 1,000 0,01648912 0,05199583 ! B cell activation GO:0042113 160 71 1,000 0,01648912 0,05192777 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01693025 0,0532473 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01693025 0,05317778 ! axon guidance GO:0007411 139 73 1,000 0,01737639 0,05450795 ! meiosis GO:0007126 121 74 1,000 0,01782751 0,05585023 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01782751 0,05577761 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01828357 0,05713022 ! meiotic cell cycle GO:0051321 122 75 1,000 0,01828357 0,05705612 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01828357 0,05698221 ! tRNA transcription GO:0009304 14 7 0,000 0,01913455 0,05955723 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01913455 0,05948028 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01913455 0,05940353 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01913455 0,05932698 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01913455 0,05925063 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01913455 0,05917447 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01913455 0,05909851 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01913455 0,05902274 ! prostate gland development GO:0030850 13 7 0,000 0,01913455 0,05894717 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01913455 0,05887179 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01913455 0,0587966 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01913455 0,0587216 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01913455 0,0586468 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01913455 0,05857219 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01913455 0,05849776 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01913455 0,05842352 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01913455 0,05834948 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01913455 0,05827562 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01913455 0,05820194 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01913455 0,05812846 ! glycolipid transport GO:0046836 10 7 0,000 0,01913455 0,05805515 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01913455 0,05798204 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01913455 0,0579091 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01913455 0,05783635 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01913455 0,05776379 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01913455 0,0576914 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01913455 0,0576192 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01913455 0,05754717 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01913455 0,05747533 ! mRNA stabilization GO:0048255 18 7 0,000 0,01913455 0,05740366 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01913455 0,05733218 ! fibril organization GO:0043206 16 7 0,000 0,01913455 0,05726087 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01913455 0,05718974 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01913455 0,05711878 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01913455 0,057048 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01913455 0,0569774 ! lipoprotein transport GO:0042953 14 7 0,000 0,01913455 0,05690697 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01913455 0,05683671 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01913455 0,05676663 ! rhythmic behavior GO:0007622 15 7 0,000 0,01913455 0,05669672 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01913455 0,05662698 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01913455 0,05655742 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01913455 0,05648802 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01913455 0,0564188 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01913455 0,05634974 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01913455 0,05628085 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01913455 0,05621213 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01913455 0,05614358 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01913455 0,0560752 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01913455 0,05600698 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01913455 0,05593893 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01913455 0,05587104 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01913455 0,05580332 ! spinal cord patterning GO:0021511 13 7 0,000 0,01913455 0,05573576 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01913455 0,05566836 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01913455 0,05560113 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01913455 0,05553406 ! adrenal gland development GO:0030325 17 7 0,000 0,01913455 0,05546715 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01913455 0,05540041 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01913455 0,05533382 ! ovulation GO:0030728 9 7 0,000 0,01913455 0,05526739 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01913455 0,05520112 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01913455 0,05513501 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01913455 0,05506906 ! microtubule nucleation GO:0007020 20 7 0,000 0,01913455 0,05500327 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01913455 0,05493763 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01913455 0,05487215 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01913455 0,05480683 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01913455 0,05474166 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01913455 0,05467665 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01913455 0,05461179 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01913455 0,05454708 ! galactose metabolic process GO:0006012 13 7 0,000 0,01913455 0,05448253 ! vesicle fusion GO:0006906 17 7 0,000 0,01913455 0,05441813 ! response to dietary excess GO:0002021 8 7 0,000 0,01913455 0,05435388 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01913455 0,05428978 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01913455 0,05422584 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01913455 0,05416204 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01913455 0,0540984 ! organ growth GO:0035265 15 7 0,000 0,01913455 0,0540349 ! purine salvage GO:0043101 10 7 0,000 0,01913455 0,05397156 ! nucleoside transport GO:0015858 8 7 0,000 0,01913455 0,05390836 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01913455 0,05384531 ! parturition GO:0007567 14 7 0,000 0,01913455 0,0537824 ! rRNA modification GO:0000154 14 7 0,000 0,01913455 0,05371965 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01913455 0,05365704 ! spindle checkpoint GO:0031577 15 7 0,000 0,01913455 0,05359457 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01913455 0,05353225 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01913455 0,05347008 ! macrophage differentiation GO:0030225 11 7 0,000 0,01913455 0,05340805 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01913455 0,05334616 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01913455 0,05328442 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01913455 0,05322282 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01913455 0,05316136 ! fibrinolysis GO:0042730 10 7 0,000 0,01913455 0,05310004 ! eating behavior GO:0042755 7 7 0,000 0,01913455 0,05303887 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01913455 0,05297783 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01913455 0,05291694 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01913455 0,05285619 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01913455 0,05279557 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01913455 0,05273509 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01913455 0,05267476 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01913455 0,05261456 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01913455 0,05255449 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01913455 0,05249457 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01913455 0,05243478 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01913455 0,05237513 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01913455 0,05231561 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01913455 0,05225623 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01913455 0,05219698 ! regulation of meiosis GO:0040020 12 7 0,000 0,01913455 0,05213787 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01913455 0,05207889 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01913455 0,05202004 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01913455 0,05196133 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01913455 0,05190275 ! transcription termination GO:0006353 13 7 0,000 0,01913455 0,0518443 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01913455 0,05178598 ! anaphase GO:0051322 17 7 0,000 0,01913455 0,05172779 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01913455 0,05166974 ! axonal fasciculation GO:0007413 18 7 0,000 0,01913455 0,05161181 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01913455 0,05155402 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01913455 0,05149635 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01913455 0,05143881 ! diuresis GO:0030146 12 7 0,000 0,01913455 0,0513814 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01913455 0,05132412 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01913455 0,05126697 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01913455 0,05120994 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01913455 0,05115304 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01913455 0,05109627 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01913455 0,05103962 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01913455 0,0509831 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01913455 0,0509267 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01913455 0,05087043 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01913455 0,05081428 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01913455 0,05075826 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01913455 0,05070235 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01913455 0,05064658 ! lymph node development GO:0048535 10 7 0,000 0,01913455 0,05059092 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01913455 0,05053539 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01913455 0,05047998 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01913455 0,05042469 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01913455 0,05036952 ! adult feeding behavior GO:0008343 9 7 0,000 0,01913455 0,05031447 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01913455 0,05025954 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01913455 0,05020473 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01913455 0,05015004 ! muscle adaptation GO:0043500 14 7 0,000 0,01913455 0,05009547 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01913455 0,05004102 ! retina homeostasis GO:0001895 12 7 0,000 0,01913455 0,04998669 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01913455 0,04993247 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01913455 0,04987837 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01913455 0,04982439 ! protein prenylation GO:0018342 18 7 0,000 0,01913455 0,04977053 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01913455 0,04971678 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01913455 0,04966315 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01913455 0,04960963 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01921042 0,0497527 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01968114 0,05091701 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02015669 0,0520913 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02063704 0,05327545 ! response to metal ion GO:0010038 140 80 1,000 0,02063704 0,05321835 ! protein import into nucleus GO:0006606 158 80 1,000 0,02063704 0,05316137 ! T cell activation GO:0042110 168 81 1,000 0,02112216 0,05435285 ! response to hypoxia GO:0001666 171 81 1,000 0,02112216 0,05429478 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,02112216 0,05423683 ! nuclear import GO:0051170 161 81 1,000 0,02112216 0,05417901 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02161202 0,05537647 ! response to drug GO:0042493 143 82 1,000 0,02161202 0,05531756 ! response to nutrient GO:0007584 125 82 1,000 0,02161202 0,05525878 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02161202 0,05520012 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02183837 0,0557191 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02183837 0,05566008 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02183837 0,05560118 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02183837 0,0555424 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02183837 0,05548375 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02183837 0,05542522 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02183837 0,05536682 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02183837 0,05530854 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02183837 0,05525038 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02183837 0,05519235 ! meiotic prophase I GO:0007128 13 8 0,000 0,02183837 0,05513443 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02183837 0,05507664 ! oligopeptide transport GO:0006857 15 8 0,000 0,02183837 0,05501897 ! UTP metabolic process GO:0046051 8 8 0,000 0,02183837 0,05496142 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02183837 0,05490398 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02183837 0,05484667 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02183837 0,05478948 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02183837 0,05473241 ! succinate metabolic process GO:0006105 14 8 0,000 0,02183837 0,05467546 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02183837 0,05461862 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02183837 0,0545619 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02183837 0,0545053 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02183837 0,05444882 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02183837 0,05439246 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02183837 0,05433621 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02183837 0,05428008 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02183837 0,05422406 ! reflex GO:0060004 16 8 0,000 0,02183837 0,05416816 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02183837 0,05411237 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02183837 0,0540567 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02183837 0,05400114 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02183837 0,0539457 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02183837 0,05389037 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02183837 0,05383516 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02183837 0,05378005 ! pigment granule organization GO:0048753 16 8 0,000 0,02183837 0,05372506 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02183837 0,05367019 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02183837 0,05361542 ! histidine metabolic process GO:0006547 16 8 0,000 0,02183837 0,05356077 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02183837 0,05350623 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02183837 0,05345179 ! glycine catabolic process GO:0006546 13 8 0,000 0,02183837 0,05339747 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02183837 0,05334326 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02183837 0,05328916 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02183837 0,05323517 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02183837 0,05318129 ! melanin metabolic process GO:0006582 15 8 0,000 0,02183837 0,05312752 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02183837 0,05307385 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02183837 0,0530203 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02183837 0,05296685 ! macrophage activation GO:0042116 12 8 0,000 0,02183837 0,05291351 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02183837 0,05286027 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02183837 0,05280715 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02183837 0,05275413 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02183837 0,05270122 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02183837 0,05264841 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02183837 0,05259571 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02183837 0,05254311 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02183837 0,05249062 ! osteoblast development GO:0002076 16 8 0,000 0,02183837 0,05243824 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02183837 0,05238596 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02183837 0,05233378 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02183837 0,0522817 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02183837 0,05222973 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02183837 0,05217787 ! response to UV-B GO:0010224 16 8 0,000 0,02183837 0,0521261 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02183837 0,05207444 ! intermediate filament organization GO:0045109 12 8 0,000 0,02183837 0,05202288 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02183837 0,05197143 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02183837 0,05192007 ! cellular extravasation GO:0045123 12 8 0,000 0,02183837 0,05186882 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02183837 0,05181767 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02183837 0,05176661 ! response to antibiotic GO:0046677 11 8 0,000 0,02183837 0,05171566 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02183837 0,05166481 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02183837 0,05161406 ! DNA topological change GO:0006265 12 8 0,000 0,02183837 0,05156341 ! response to tropane GO:0014073 15 8 0,000 0,02183837 0,05151286 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02183837 0,0514624 ! melanosome transport GO:0032402 13 8 0,000 0,02183837 0,05141205 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02183837 0,05136179 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02183837 0,05131163 ! mast cell activation GO:0045576 14 8 0,000 0,02183837 0,05126157 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02183837 0,05121161 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02183837 0,05116175 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02183837 0,05111198 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02183837 0,05106231 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02183837 0,05101273 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02183837 0,05096325 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02183837 0,05091387 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02183837 0,05086458 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02183837 0,05081539 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02183837 0,05076629 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02183837 0,05071729 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02183837 0,05066838 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02183837 0,05061957 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02183837 0,05057085 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02183837 0,05052222 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02183837 0,05047369 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02183837 0,05042525 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02183837 0,05037691 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02183837 0,05032865 ! hormone catabolic process GO:0042447 17 8 0,000 0,02183837 0,05028049 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02183837 0,05023242 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02183837 0,05018444 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02183837 0,05013656 ! ATP catabolic process GO:0006200 11 8 0,000 0,02183837 0,05008876 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02183837 0,05004106 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02183837 0,04999345 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02183837 0,04994593 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02183837 0,04989849 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02183837 0,04985115 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02183837 0,0498039 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02183837 0,04975674 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02183837 0,04970966 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02183837 0,04966268 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02183837 0,04961578 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02183837 0,04956897 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02183837 0,04952226 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02183837 0,04947562 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02183837 0,04942908 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02183837 0,04938263 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02183837 0,04933626 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02183837 0,04928997 ! response to oxygen levels GO:0070482 176 83 1,000 0,02210658 0,04984858 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02210658 0,04980191 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02260583 0,05087898 ! response to unfolded protein GO:0006986 131 85 1,000 0,02310973 0,0519645 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02310973 0,05191598 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,02361826 0,05300889 ! mitochondrion organization GO:0007005 148 86 1,000 0,02361826 0,05295948 ! amine transport GO:0015837 155 86 1,000 0,02361826 0,05291017 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,02413138 0,05400939 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,02413138 0,05395919 ! axon extension GO:0048675 15 9 0,000 0,02453482 0,05481037 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02453482 0,05475953 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02453482 0,05470878 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02453482 0,05465812 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02453482 0,05460756 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02453482 0,05455709 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02453482 0,05450671 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02453482 0,05445643 ! phosphate transport GO:0006817 19 9 0,000 0,02453482 0,05440624 ! reproductive behavior GO:0019098 19 9 0,000 0,02453482 0,05435614 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02453482 0,05430614 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02453482 0,05425622 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02453482 0,0542064 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02453482 0,05415667 ! GTP metabolic process GO:0046039 9 9 0,000 0,02453482 0,05410703 ! RNA methylation GO:0001510 15 9 0,000 0,02453482 0,05405748 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02453482 0,05400803 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02453482 0,05395866 ! artery development GO:0060840 24 9 0,000 0,02453482 0,05390938 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02453482 0,05386019 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02453482 0,0538111 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02453482 0,05376209 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02453482 0,05371317 ! chemosensory behavior GO:0007635 20 9 0,000 0,02453482 0,05366434 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02453482 0,0536156 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02453482 0,05356694 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02453482 0,05351838 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02453482 0,0534699 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02453482 0,05342151 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02453482 0,05337321 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02453482 0,053325 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02453482 0,05327687 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02453482 0,05322883 ! protein targeting to ER GO:0045047 22 9 0,000 0,02453482 0,05318088 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02453482 0,05313301 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02453482 0,05308523 ! T cell selection GO:0045058 23 9 0,000 0,02453482 0,05303753 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02453482 0,05298992 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02453482 0,0529424 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02453482 0,05289496 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02453482 0,0528476 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02453482 0,05280033 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02453482 0,05275315 ! mannose metabolic process GO:0006013 13 9 0,000 0,02453482 0,05270605 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02453482 0,05265903 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02453482 0,0526121 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02453482 0,05256525 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02453482 0,05251848 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02453482 0,0524718 ! ruffle organization GO:0031529 15 9 0,000 0,02453482 0,0524252 ! retinol metabolic process GO:0042572 18 9 0,000 0,02453482 0,05237868 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02453482 0,05233224 ! behavioral fear response GO:0001662 22 9 0,000 0,02453482 0,05228589 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02453482 0,05223962 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02453482 0,05219343 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02453482 0,05214733 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02453482 0,0521013 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02453482 0,05205535 ! segment specification GO:0007379 13 9 0,000 0,02453482 0,05200949 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02453482 0,05196371 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02453482 0,05191801 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02453482 0,05187238 ! response to amine stimulus GO:0014075 13 9 0,000 0,02453482 0,05182684 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02453482 0,05178138 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02453482 0,051736 ! erythrocyte development GO:0048821 15 9 0,000 0,02453482 0,05169069 ! gas homeostasis GO:0033483 16 9 0,000 0,02453482 0,05164547 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02453482 0,05160033 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02453482 0,05155526 ! renal water homeostasis GO:0003091 14 9 0,000 0,02453482 0,05151027 ! postreplication repair GO:0006301 22 9 0,000 0,02453482 0,05146536 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02453482 0,05142053 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02453482 0,05137578 ! icosanoid secretion GO:0032309 15 9 0,000 0,02453482 0,05133111 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02453482 0,05128651 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02453482 0,05124199 ! regulation of cell division GO:0051302 15 9 0,000 0,02453482 0,05119755 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02453482 0,05115318 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02453482 0,05110889 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02453482 0,05106468 ! sterol catabolic process GO:0016127 11 9 0,000 0,02453482 0,05102055 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02453482 0,05097649 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02453482 0,0509325 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02453482 0,0508886 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02453482 0,05084477 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02453482 0,05080101 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02453482 0,05075733 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02453482 0,05071372 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02453482 0,05067019 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02453482 0,05062673 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02453482 0,05058335 ! purine base metabolic process GO:0006144 21 9 0,000 0,02453482 0,05054004 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02453482 0,05049681 ! pigment granule transport GO:0051904 17 9 0,000 0,02453482 0,05045365 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02453482 0,05041057 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02453482 0,05036755 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02453482 0,05032461 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02453482 0,05028175 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02453482 0,05023896 ! mitochondrion localization GO:0051646 15 9 0,000 0,02453482 0,05019623 ! regulation of neurological system process GO:0031644 148 88 1,000 0,02464906 0,05038712 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02517129 0,05141096 ! ossification GO:0001503 188 90 1,000 0,02569802 0,05244227 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02569802 0,05239783 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,02569802 0,05235346 ! bone development GO:0060348 189 91 1,000 0,02622923 0,05339047 ! response to protein stimulus GO:0051789 149 91 1,000 0,02622923 0,05334534 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02722392 0,05532159 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02722392 0,0552749 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02722392 0,0552283 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02722392 0,05518177 ! synapsis GO:0007129 13 10 0,000 0,02722392 0,05513532 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02722392 0,05508895 ! N-glycan processing GO:0006491 20 10 0,000 0,02722392 0,05504266 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02722392 0,05499644 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02722392 0,0549503 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02722392 0,05490424 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02722392 0,05485826 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02722392 0,05481235 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02722392 0,05476652 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02722392 0,05472077 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02722392 0,05467509 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02722392 0,05462949 ! androgen metabolic process GO:0008209 17 10 0,000 0,02722392 0,05458397 ! phospholipid efflux GO:0033700 16 10 0,000 0,02722392 0,05453852 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02722392 0,05449315 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02722392 0,05444785 ! lung alveolus development GO:0048286 26 10 0,000 0,02722392 0,05440263 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02722392 0,05435748 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02722392 0,05431241 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02722392 0,05426741 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02722392 0,05422248 ! endoderm development GO:0007492 16 10 0,000 0,02722392 0,05417764 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02722392 0,05413286 ! arginine catabolic process GO:0006527 13 10 0,000 0,02722392 0,05408816 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02722392 0,05404353 ! proline metabolic process GO:0006560 13 10 0,000 0,02722392 0,05399898 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02722392 0,0539545 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02722392 0,05391009 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02722392 0,05386576 ! V(D)J recombination GO:0033151 28 10 0,000 0,02722392 0,0538215 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02722392 0,05377731 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02722392 0,05373319 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02722392 0,05368915 ! B cell proliferation GO:0042100 18 10 0,000 0,02722392 0,05364518 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02722392 0,05360128 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02722392 0,05355745 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02722392 0,05351369 ! epithelial cell development GO:0002064 20 10 0,000 0,02722392 0,05347001 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02722392 0,0534264 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02722392 0,05338285 ! macroautophagy GO:0016236 17 10 0,000 0,02722392 0,05333938 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02722392 0,05329598 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02722392 0,05325265 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02722392 0,05320939 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02722392 0,0531662 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02722392 0,05312308 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02722392 0,05308003 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02722392 0,05303705 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02722392 0,05299414 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02722392 0,0529513 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02722392 0,05290853 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02722392 0,05286583 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02722392 0,05282319 ! response to dsRNA GO:0043331 20 10 0,000 0,02722392 0,05278063 ! DNA ligation GO:0006266 19 10 0,000 0,02722392 0,05273813 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02722392 0,05269571 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02722392 0,05265335 ! melanosome localization GO:0032400 16 10 0,000 0,02722392 0,05261105 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02722392 0,05256883 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02722392 0,05252667 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02722392 0,05248458 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02722392 0,05244256 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02722392 0,05240061 ! mRNA cleavage GO:0006379 17 10 0,000 0,02722392 0,05235872 ! protein sumoylation GO:0016925 15 10 0,000 0,02722392 0,0523169 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02722392 0,05227515 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02722392 0,05223346 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02722392 0,05219184 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02722392 0,05215029 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02722392 0,0521088 ! salivary gland development GO:0007431 27 10 0,000 0,02722392 0,05206738 ! prophase GO:0051324 15 10 0,000 0,02722392 0,05202602 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02722392 0,05198473 ! apical protein localization GO:0045176 15 10 0,000 0,02722392 0,05194351 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02722392 0,05190235 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02722392 0,05186125 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02722392 0,05182022 ! midbrain development GO:0030901 13 10 0,000 0,02722392 0,05177926 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02722392 0,05173836 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02722392 0,05169752 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02722392 0,05165675 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02722392 0,05161605 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02722392 0,0515754 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02722392 0,05153482 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02722392 0,05149431 ! detection of calcium ion GO:0005513 23 10 0,000 0,02722392 0,05145386 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02722392 0,05141347 ! blastocyst formation GO:0001825 17 10 0,000 0,02722392 0,05137315 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02722392 0,05133289 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02722392 0,05129269 ! activation of innate immune response GO:0002218 12 10 0,000 0,02722392 0,05125255 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02722392 0,05121248 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02722392 0,05117247 ! response to nicotine GO:0035094 20 10 0,000 0,02722392 0,05113252 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02722392 0,05109264 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02722392 0,05105282 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02722392 0,05101305 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,027305 0,05112515 ! regulation of membrane potential GO:0042391 164 93 1,000 0,027305 0,0510854 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02784949 0,05206361 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02895155 0,05408186 ! mRNA transport GO:0051028 169 96 1,000 0,02895155 0,05403991 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02990571 0,05577762 ! respiratory burst GO:0045730 17 11 0,000 0,02990571 0,05573441 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02990571 0,05569128 ! neuron fate specification GO:0048665 17 11 0,000 0,02990571 0,05564821 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02990571 0,0556052 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02990571 0,05556226 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02990571 0,05551939 ! thyroid gland development GO:0030878 26 11 0,000 0,02990571 0,05547658 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02990571 0,05543384 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02990571 0,05539117 ! response to pain GO:0048265 24 11 0,000 0,02990571 0,05534856 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02990571 0,05530602 ! T cell proliferation GO:0042098 26 11 0,000 0,02990571 0,05526354 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02990571 0,05522113 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02990571 0,05517878 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02990571 0,0551365 ! bone resorption GO:0045453 16 11 0,000 0,02990571 0,05509428 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02990571 0,05505213 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02990571 0,05501004 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02990571 0,05496801 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02990571 0,05492605 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02990571 0,05488416 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02990571 0,05484232 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02990571 0,05480056 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02990571 0,05475885 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02990571 0,05471721 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02990571 0,05467563 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02990571 0,05463412 ! UV protection GO:0009650 19 11 0,000 0,02990571 0,05459266 ! adult heart development GO:0007512 14 11 0,000 0,02990571 0,05455127 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02990571 0,05450995 ! temperature homeostasis GO:0001659 17 11 0,000 0,02990571 0,05446868 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02990571 0,05442748 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02990571 0,05438634 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02990571 0,05434526 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02990571 0,05430425 ! regulation of organ growth GO:0046620 13 11 0,000 0,02990571 0,0542633 ! pigment granule localization GO:0051875 20 11 0,000 0,02990571 0,0542224 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02990571 0,05418157 ! vasoconstriction GO:0042310 18 11 0,000 0,02990571 0,0541408 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02990571 0,0541001 ! embryonic axis specification GO:0000578 18 11 0,000 0,02990571 0,05405945 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02990571 0,05401887 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02990571 0,05397834 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02990571 0,05393788 ! DNA methylation GO:0006306 19 11 0,000 0,02990571 0,05389748 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02990571 0,05385713 ! zymogen activation GO:0031638 15 11 0,000 0,02990571 0,05381685 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02990571 0,05377663 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02990571 0,05373647 ! nucleosome positioning GO:0016584 15 11 0,000 0,02990571 0,05369637 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02990571 0,05365632 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02990571 0,05361634 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02990571 0,05357642 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02990571 0,05353655 ! acid secretion GO:0046717 18 11 0,000 0,02990571 0,05349675 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02990571 0,05345701 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02990571 0,05341732 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02990571 0,05337769 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02990571 0,05333812 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02990571 0,05329861 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02990571 0,05325916 ! cholesterol efflux GO:0033344 19 11 0,000 0,02990571 0,05321977 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02990571 0,05318044 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02990571 0,05314116 ! germ cell migration GO:0008354 25 11 0,000 0,02990571 0,05310194 ! embryonic gut development GO:0048566 15 11 0,000 0,02990571 0,05306278 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02990571 0,05302368 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02990571 0,05298463 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02990571 0,05294564 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02990571 0,05290671 ! defense response to fungus GO:0050832 13 11 0,000 0,02990571 0,05286784 ! lysogeny GO:0030069 21 11 0,000 0,02990571 0,05282902 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02990571 0,05279026 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02990571 0,05275156 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02990571 0,05271292 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02990571 0,05267433 ! nucleus localization GO:0051647 19 11 0,000 0,02990571 0,05263579 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02990571 0,05259732 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03063695 0,05384404 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03258018 0,05721746 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03258018 0,05717573 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03258018 0,05713405 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03258018 0,05709244 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03258018 0,05705089 ! cartilage condensation GO:0001502 20 12 0,000 0,03258018 0,0570094 ! mating GO:0007618 17 12 0,000 0,03258018 0,05696797 ! protein complex disassembly GO:0043241 27 12 0,000 0,03258018 0,0569266 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03258018 0,05688529 ! hippocampus development GO:0021766 26 12 0,000 0,03258018 0,05684403 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03258018 0,05680284 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03258018 0,05676171 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03258018 0,05672064 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03258018 0,05667963 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03258018 0,05663867 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03258018 0,05659778 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03258018 0,05655694 ! drug transport GO:0015893 16 12 0,000 0,03258018 0,05651617 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03258018 0,05647545 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03258018 0,05643479 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03258018 0,05639419 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03258018 0,05635365 ! focal adhesion formation GO:0048041 35 12 0,000 0,03258018 0,05631316 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03258018 0,05627274 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03258018 0,05623237 ! forebrain cell migration GO:0021885 21 12 0,000 0,03258018 0,05619206 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03258018 0,05615181 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03258018 0,05611161 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03258018 0,05607148 ! entry into host cell GO:0030260 32 12 0,000 0,03258018 0,0560314 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03258018 0,05599137 ! monoamine transport GO:0015844 18 12 0,000 0,03258018 0,05595141 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03258018 0,0559115 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03258018 0,05587165 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03258018 0,05583185 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03258018 0,05579212 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03258018 0,05575243 ! protein homotetramerization GO:0051289 21 12 0,000 0,03258018 0,05571281 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03258018 0,05567324 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03258018 0,05563373 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03258018 0,05559427 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03258018 0,05555487 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03258018 0,05551553 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03258018 0,05547624 ! cranial nerve development GO:0021545 20 12 0,000 0,03258018 0,055437 ! fucose catabolic process GO:0019317 22 12 0,000 0,03258018 0,05539783 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03258018 0,0553587 ! histone methylation GO:0016571 26 12 0,000 0,03258018 0,05531964 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03258018 0,05528062 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03258018 0,05524167 ! gland morphogenesis GO:0022612 29 12 0,000 0,03258018 0,05520276 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03258018 0,05516391 ! T cell homeostasis GO:0043029 25 12 0,000 0,03258018 0,05512512 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03258018 0,05508638 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03258018 0,0550477 ! spleen development GO:0048536 22 12 0,000 0,03258018 0,05500907 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03258018 0,05497049 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03258018 0,05493197 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03258018 0,0548935 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03258018 0,05485509 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03258018 0,05481673 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03258018 0,05477842 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03258018 0,05474017 ! response to cold GO:0009409 17 12 0,000 0,03258018 0,05470197 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03258018 0,05466382 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03258018 0,05462573 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03524738 0,05905654 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03524738 0,05901544 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03524738 0,0589744 ! peroxisomal transport GO:0043574 24 13 0,000 0,03524738 0,05893342 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03524738 0,05889249 ! lipid localization GO:0010876 28 13 0,000 0,03524738 0,05885162 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03524738 0,05881081 ! organelle fusion GO:0048284 32 13 0,000 0,03524738 0,05877005 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03524738 0,05872936 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03524738 0,05868871 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03524738 0,05864813 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03524738 0,05860759 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03524738 0,05856712 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03524738 0,0585267 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03524738 0,05848634 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03524738 0,05844603 ! methionine metabolic process GO:0006555 27 13 0,000 0,03524738 0,05840578 ! plasma membrane organization GO:0007009 24 13 0,000 0,03524738 0,05836558 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03524738 0,05832544 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03524738 0,05828535 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03524738 0,05824532 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03524738 0,05820535 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03524738 0,05816542 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03524738 0,05812556 ! exocrine system development GO:0035272 32 13 0,000 0,03524738 0,05808575 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03524738 0,05804599 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03524738 0,05800629 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03524738 0,05796664 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03524738 0,05792704 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03524738 0,0578875 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03524738 0,05784801 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03524738 0,05780858 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03524738 0,0577692 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03524738 0,05772988 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03524738 0,0576906 ! ribosome assembly GO:0042255 17 13 0,000 0,03524738 0,05765139 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03524738 0,05761222 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03524738 0,05757311 ! chromatin silencing GO:0006342 26 13 0,000 0,03524738 0,05753405 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03524738 0,05749504 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03524738 0,05745609 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03524738 0,05741719 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03524738 0,05737834 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03524738 0,05733955 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03524738 0,0573008 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03524738 0,05726211 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03524738 0,05722347 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03524738 0,05718489 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03524738 0,05714635 ! embryonic placenta development GO:0001892 23 13 0,000 0,03524738 0,05710787 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03524738 0,05706944 ! insulin secretion GO:0030073 23 13 0,000 0,03524738 0,05703106 ! actin filament polymerization GO:0030041 24 13 0,000 0,03524738 0,05699273 ! acrosome reaction GO:0007340 18 13 0,000 0,03524738 0,05695446 ! rRNA transcription GO:0009303 25 14 0,000 0,0379073 0,06121139 ! lactation GO:0007595 26 14 0,000 0,0379073 0,06117034 ! reproductive cellular process GO:0048610 20 14 0,000 0,0379073 0,06112934 ! tRNA modification GO:0006400 20 14 0,000 0,0379073 0,0610884 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0379073 0,06104751 ! water transport GO:0006833 21 14 0,000 0,0379073 0,06100667 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0379073 0,06096589 ! non-recombinational repair GO:0000726 25 14 0,000 0,0379073 0,06092517 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0379073 0,0608845 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0379073 0,06084388 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0379073 0,06080332 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0379073 0,06076281 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0379073 0,06072235 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0379073 0,06068195 ! palate development GO:0060021 31 14 0,000 0,0379073 0,06064161 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0379073 0,06060131 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0379073 0,06056107 ! arginine metabolic process GO:0006525 17 14 0,000 0,0379073 0,06052089 ! regulation of heart rate GO:0002027 24 14 0,000 0,0379073 0,06048075 ! organic alcohol transport GO:0015850 29 14 0,000 0,0379073 0,06044067 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0379073 0,06040065 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0379073 0,06036067 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0379073 0,06032075 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0379073 0,06028088 ! L-amino acid transport GO:0015807 30 14 0,000 0,0379073 0,06024107 ! bone mineralization GO:0030282 17 14 0,000 0,0379073 0,0602013 ! stem cell development GO:0048864 43 14 0,000 0,0379073 0,06016159 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0379073 0,06012194 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0379073 0,06008233 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0379073 0,06004278 ! cerebellum development GO:0021549 21 14 0,000 0,0379073 0,06000327 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0379073 0,05996382 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0379073 0,05992443 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0379073 0,05988508 ! cofactor transport GO:0051181 26 14 0,000 0,0379073 0,05984578 ! NADP metabolic process GO:0006739 24 14 0,000 0,0379073 0,05980654 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0379073 0,05976735 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0379073 0,05972821 ! intestinal absorption GO:0050892 25 14 0,000 0,0379073 0,05968912 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0379073 0,05965008 ! oxygen transport GO:0015671 21 14 0,000 0,0379073 0,0596111 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0379073 0,05957216 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0379073 0,05953327 ! regulation of axon extension GO:0030516 37 14 0,000 0,0379073 0,05949444 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0379073 0,05945566 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04055999 0,06357481 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04055999 0,06353342 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04055999 0,06349208 ! superoxide anion generation GO:0042554 20 15 0,000 0,04055999 0,0634508 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04055999 0,06340957 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04055999 0,0633684 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04055999 0,06332727 ! copper ion transport GO:0006825 20 15 0,000 0,04055999 0,06328621 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04055999 0,06324519 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04055999 0,06320423 ! sulfate transport GO:0008272 23 15 0,000 0,04055999 0,06316332 ! response to cAMP GO:0051591 22 15 0,000 0,04055999 0,06312246 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04055999 0,06308166 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04055999 0,06304091 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04055999 0,06300021 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04055999 0,06295957 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04055999 0,06291897 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04055999 0,06287843 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04055999 0,06283795 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04055999 0,06279751 ! pituitary gland development GO:0021983 29 15 0,000 0,04055999 0,06275712 ! vesicle coating GO:0006901 33 15 0,000 0,04055999 0,06271679 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04055999 0,06267651 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04055999 0,06263628 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04055999 0,06259611 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04055999 0,06255598 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04055999 0,06251591 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04055999 0,06247588 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04055999 0,06243591 ! histone deacetylation GO:0016575 20 15 0,000 0,04055999 0,06239599 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04055999 0,06235612 ! tissue regeneration GO:0042246 26 15 0,000 0,04055999 0,0623163 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04055999 0,06227653 ! water homeostasis GO:0030104 27 15 0,000 0,04055999 0,06223682 ! muscle maintenance GO:0046716 26 15 0,000 0,04055999 0,06219715 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04055999 0,06215753 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04055999 0,06211797 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04055999 0,06207845 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04055999 0,06203899 ! cell killing GO:0001906 29 15 0,000 0,04055999 0,06199957 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04055999 0,06196021 ! detection of bacterium GO:0016045 18 15 0,000 0,04055999 0,06192089 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04055999 0,06188163 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04055999 0,06184241 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04055999 0,06180325 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04055999 0,06176413 ! peptide hormone processing GO:0016486 23 15 0,000 0,04055999 0,06172507 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04320544 0,06570942 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04320544 0,06566791 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04320544 0,06562645 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04320544 0,06558505 ! bone remodeling GO:0046849 27 16 0,000 0,04320544 0,06554369 ! filopodium assembly GO:0046847 32 16 0,000 0,04320544 0,06550239 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04320544 0,06546114 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04320544 0,06541995 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04320544 0,0653788 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04320544 0,06533771 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04320544 0,06529667 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04320544 0,06525568 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04320544 0,06521474 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04320544 0,06517385 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04320544 0,06513302 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04320544 0,06509223 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04320544 0,0650515 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04320544 0,06501082 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04320544 0,06497019 ! response to osmotic stress GO:0006970 25 16 0,000 0,04320544 0,0649296 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04320544 0,06488907 GO:0031114|regulation of microtubule depolymerization, ! fructose metabolic process GO:0006000 25 16 0,000 0,04320544 0,06484859 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04320544 0,06480816 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04320544 0,06476779 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04320544 0,06472746 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04320544 0,06468718 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04320544 0,06464695 ! axon cargo transport GO:0008088 43 16 0,000 0,04320544 0,06460677 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04320544 0,06456664 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04320544 0,06452657 ! DNA replication initiation GO:0006270 27 16 0,000 0,04320544 0,06448654 ! neuron recognition GO:0008038 35 16 0,000 0,04320544 0,06444656 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04320544 0,06440663 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04320544 0,06436675 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04320544 0,06432692 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04320544 0,06428713 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04320544 0,0642474 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04320544 0,06420772 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04320544 0,06416808 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04320544 0,0641285 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04320544 0,06408896 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04320544 0,06404947 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04320544 0,06401003 ! defense response to virus GO:0051607 37 16 0,000 0,04320544 0,06397064 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04584369 0,06783513 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04584369 0,06779344 ! metencephalon development GO:0022037 30 17 0,000 0,04584369 0,0677518 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04584369 0,06771021 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04584369 0,06766867 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04584369 0,06762718 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04584369 0,06758574 ! endothelial cell migration GO:0043542 28 17 0,000 0,04584369 0,06754435 ! inositol metabolic process GO:0006020 28 17 0,000 0,04584369 0,06750301 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04584369 0,06746173 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04584369 0,06742049 ! glial cell development GO:0021782 27 17 0,000 0,04584369 0,06737931 ! limbic system development GO:0021761 36 17 0,000 0,04584369 0,06733817 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04584369 0,06729709 ! adult walking behavior GO:0007628 33 17 0,000 0,04584369 0,06725605 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04584369 0,06721507 ! heart looping GO:0001947 30 17 0,000 0,04584369 0,06717413 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04584369 0,06713325 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04584369 0,06709241 ! myoblast differentiation GO:0045445 45 17 0,000 0,04584369 0,06705163 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04584369 0,06701089 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04584369 0,0669702 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04584369 0,06692957 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04584369 0,06688898 ! glycine metabolic process GO:0006544 28 17 0,000 0,04584369 0,06684844 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04584369 0,06680795 ! NAD metabolic process GO:0019674 29 17 0,000 0,04584369 0,06676751 ! membrane budding GO:0006900 37 17 0,000 0,04584369 0,06672712 ! DNA integration GO:0015074 29 17 0,000 0,04584369 0,06668677 ! regulation of protein binding GO:0043393 33 17 0,000 0,04584369 0,06664648 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04584369 0,06660623 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04584369 0,06656604 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04584369 0,06652589 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04584369 0,06648579 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04584369 0,06644574 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04584369 0,06640573 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04584369 0,06636578 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04584369 0,06632587 ! steroid catabolic process GO:0006706 31 17 0,000 0,04584369 0,06628601 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04584369 0,0662462 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04584369 0,06620644 ! gas transport GO:0015669 25 17 0,000 0,04584369 0,06616672 ! organic cation transport GO:0015695 31 17 0,000 0,04584369 0,06612705 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04584369 0,06608743 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04584369 0,06604786 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04584369 0,06600833 ! microspike assembly GO:0030035 36 17 0,000 0,04584369 0,06596885 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04584369 0,06592942 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04584369 0,06589004 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04847476 0,06963001 ! neuron maturation GO:0042551 42 18 0,000 0,04847476 0,06958846 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04847476 0,06954697 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04847476 0,06950552 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04847476 0,06946412 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04847476 0,06942277 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04847476 0,06938148 ! memory GO:0007613 31 18 0,000 0,04847476 0,06934023 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04847476 0,06929903 GO:0050886|endocrine process, ! patterning of blood vessels GO:0001569 39 18 0,000 0,04847476 0,06925787 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04847476 0,06921677 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04847476 0,06917572 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04847476 0,06913471 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04847476 0,06909376 ! response to retinoic acid GO:0032526 26 18 0,000 0,04847476 0,06905285 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04847476 0,06901199 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04847476 0,06897118 ! response to fungus GO:0009620 21 18 0,000 0,04847476 0,06893041 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04847476 0,0688897 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04847476 0,06884903 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04847476 0,06880841 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04847476 0,06876784 ! vitamin transport GO:0051180 27 18 0,000 0,04847476 0,06872732 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04847476 0,06868684 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04847476 0,06864642 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04847476 0,06860604 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04847476 0,0685657 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04847476 0,06852542 ! nerve development GO:0021675 28 18 0,000 0,04847476 0,06848518 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04847476 0,06844499 ! protein secretion GO:0009306 39 19 0,000 0,05109865 0,07210754 ! positive regulation of translation GO:0045727 30 19 0,000 0,05109865 0,07206527 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05109865 0,07202305 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05109865 0,07198088 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05109865 0,07193877 ! skin development GO:0043588 36 19 0,000 0,05109865 0,0718967 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05109865 0,07185468 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05109865 0,0718127 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05109865 0,07177078 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05109865 0,07172891 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05109865 0,07168708 ! cerebral cortex development GO:0021987 36 19 0,000 0,05109865 0,07164531 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05109865 0,07160358 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05109865 0,0715619 ! heme metabolic process GO:0042168 36 19 0,000 0,05109865 0,07152027 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05109865 0,07147869 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05109865 0,07143716 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05109865 0,07139567 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05109865 0,07135424 ! peptide cross-linking GO:0018149 37 19 0,000 0,05109865 0,07131285 ! protein export from nucleus GO:0006611 36 19 0,000 0,05109865 0,07127151 ! heart process GO:0003015 30 19 0,000 0,05109865 0,07123021 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05109865 0,07118897 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,05109865 0,07114777 ! cellular pigmentation GO:0033059 36 19 0,000 0,05109865 0,07110662 ! G1 phase GO:0051318 40 19 0,000 0,05109865 0,07106552 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05109865 0,07102447 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05109865 0,07098346 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05109865 0,0709425 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05109865 0,07090159 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05109865 0,07086072 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05109865 0,0708199 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05109865 0,07077913 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05109865 0,07073841 ! cilium assembly GO:0042384 37 19 0,000 0,05109865 0,07069773 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05109865 0,0706571 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0537154 0,07423276 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0537154 0,07419015 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0537154 0,07414758 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0537154 0,07410507 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0537154 0,0740626 ! response to vitamin GO:0033273 31 20 0,000 0,0537154 0,07402018 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0537154 0,07397781 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0537154 0,07393549 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0537154 0,07389322 ! response to alkaloid GO:0043279 38 20 0,000 0,0537154 0,07385099 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0537154 0,07380882 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0537154 0,07376669 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0537154 0,07372461 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0537154 0,07368258 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0537154 0,07364059 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0537154 0,07359866 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0537154 0,07355677 ! body fluid secretion GO:0007589 31 20 0,000 0,0537154 0,07351493 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0537154 0,07347313 ! peptide secretion GO:0002790 35 20 0,000 0,0537154 0,07343139 ! stem cell differentiation GO:0048863 53 20 0,000 0,0537154 0,07338969 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0537154 0,07334804 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0537154 0,07330643 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0537154 0,07326488 ! sensory perception of pain GO:0019233 30 20 0,000 0,0537154 0,07322337 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0537154 0,0731819 ! diencephalon development GO:0021536 34 20 0,000 0,0537154 0,07314049 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0537154 0,07309912 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0537154 0,0730578 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0537154 0,07301652 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0537154 0,07297529 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0537154 0,07293411 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0537154 0,07289297 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0537154 0,07285188 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0537154 0,07281084 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0537154 0,07276984 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0537154 0,07272889 ! actin filament-based movement GO:0030048 43 20 0,000 0,0537154 0,07268799 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0537154 0,07264713 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0537154 0,07260631 ! negative regulation of translation GO:0017148 29 20 0,000 0,0537154 0,07256555 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0537154 0,07252483 ! regulation of cell killing GO:0031341 42 21 0,000 0,05632501 0,0760056 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05632501 0,07596299 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05632501 0,07592044 ! hormone secretion GO:0046879 38 21 0,000 0,05632501 0,07587793 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05632501 0,07583547 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05632501 0,07579305 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05632501 0,07575069 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05632501 0,07570837 ! axis specification GO:0009798 38 21 0,000 0,05632501 0,0756661 ! ovarian follicle development GO:0001541 35 21 0,000 0,05632501 0,07562387 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05632501 0,07558169 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05632501 0,07553956 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05632501 0,07549748 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05632501 0,07545544 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05632501 0,07541345 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05632501 0,07537151 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05632501 0,07532962 ! cytolysis GO:0019835 24 21 0,000 0,05632501 0,07528777 ! vasodilation GO:0042311 39 21 0,000 0,05632501 0,07524596 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05632501 0,07520421 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05632501 0,07516249 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05632501 0,07512083 ! DNA modification GO:0006304 34 21 0,000 0,05632501 0,07507921 ! collagen fibril organization GO:0030199 59 21 0,000 0,05632501 0,07503764 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05632501 0,07499611 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05632501 0,07495463 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05632501 0,0749132 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05632501 0,07487181 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05632501 0,07483047 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05632501 0,07478917 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05632501 0,07474792 ! collagen catabolic process GO:0030574 28 21 0,000 0,05632501 0,07470671 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05632501 0,07466555 ! gut development GO:0048565 39 21 0,000 0,05632501 0,07462444 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05892752 0,0780295 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05892752 0,07798658 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05892752 0,07794371 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05892752 0,07790088 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05892752 0,0778581 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05892752 0,07781537 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05892752 0,07777269 ! regeneration GO:0031099 41 22 0,000 0,05892752 0,07773005 ! keratinization GO:0031424 28 22 0,000 0,05892752 0,07768746 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05892752 0,07764491 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05892752 0,07760241 ! sensory perception of taste GO:0050909 28 22 0,000 0,05892752 0,07755996 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05892752 0,07751755 ! lysosome organization GO:0007040 41 22 0,000 0,05892752 0,0774752 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05892752 0,07743288 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05892752 0,07739062 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05892752 0,07734839 ! fucose metabolic process GO:0006004 39 22 0,000 0,05892752 0,07730622 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05892752 0,07726409 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05892752 0,07722201 ! ureteric bud development GO:0001657 43 22 0,000 0,05892752 0,07717997 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05892752 0,07713798 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05892752 0,07709603 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05892752 0,07705413 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05892752 0,07701228 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05892752 0,07697047 ! sarcomere organization GO:0045214 30 22 0,000 0,05892752 0,07692871 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05892752 0,07688699 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05892752 0,07684532 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05892752 0,07680369 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05892752 0,0767621 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05892752 0,07672057 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06152293 0,08005634 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06152293 0,08001307 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06152293 0,07996984 ! gluconeogenesis GO:0006094 33 23 0,000 0,06152293 0,07992666 ! viral genome replication GO:0019079 41 23 0,000 0,06152293 0,07988353 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06152293 0,07984044 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06152293 0,0797974 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06152293 0,07975441 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06152293 0,07971146 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06152293 0,07966856 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06152293 0,0796257 ! visual behavior GO:0007632 42 23 0,000 0,06152293 0,07958289 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06152293 0,07954013 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06152293 0,07949741 ! response to ethanol GO:0045471 46 23 0,000 0,06152293 0,07945474 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06152293 0,07941211 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06152293 0,07936953 ! peroxisome organization GO:0007031 37 23 0,000 0,06152293 0,079327 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06152293 0,07928451 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06152293 0,07924206 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06152293 0,07919967 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06152293 0,07915731 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06152293 0,07911501 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06152293 0,07907274 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06152293 0,07903053 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06152293 0,07898835 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06152293 0,07894623 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06152293 0,07890414 ! fatty acid transport GO:0015908 44 23 0,000 0,06152293 0,07886211 ! platelet activation GO:0030168 37 23 0,000 0,06152293 0,07882011 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06152293 0,07877817 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06152293 0,07873626 ! hormone transport GO:0009914 40 23 0,000 0,06152293 0,0786944 ! cell-cell recognition GO:0009988 25 23 0,000 0,06152293 0,07865259 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06152293 0,07861082 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06152293 0,0785691 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06152293 0,07852741 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06152293 0,07848578 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06411128 0,08174442 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06411128 0,08170113 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06411128 0,08165788 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06411128 0,08161467 ! vesicle docking GO:0048278 47 24 0,000 0,06411128 0,08157151 ! spinal cord development GO:0021510 47 24 0,000 0,06411128 0,0815284 ! vacuole organization GO:0007033 43 24 0,000 0,06411128 0,08148533 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06411128 0,08144231 ! digestive system process GO:0022600 39 24 0,000 0,06411128 0,08139933 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06411128 0,0813564 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06411128 0,08131351 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06411128 0,08127067 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06411128 0,08122787 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06411128 0,08118512 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06411128 0,08114241 ! membrane depolarization GO:0051899 39 24 0,000 0,06411128 0,08109975 ! pallium development GO:0021543 49 24 0,000 0,06411128 0,08105714 ! pentose metabolic process GO:0019321 35 24 0,000 0,06411128 0,08101456 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06411128 0,08097204 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06411128 0,08092955 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06411128 0,08088712 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06411128 0,08084472 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06411128 0,08080237 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06411128 0,08076007 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06411128 0,08071781 ! regulation of amine transport GO:0051952 40 24 0,000 0,06411128 0,08067559 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06669257 0,08387993 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06669257 0,08383611 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06669257 0,08379233 ! phototransduction GO:0007602 33 25 0,000 0,06669257 0,0837486 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06669257 0,08370491 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06669257 0,08366127 ! sperm motility GO:0030317 31 25 0,000 0,06669257 0,08361767 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06669257 0,08357412 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06669257 0,08353062 ! neural crest cell development GO:0014032 54 25 0,000 0,06669257 0,08348716 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06669257 0,08344374 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06669257 0,08340037 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06669257 0,08335705 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06669257 0,08331377 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06669257 0,08327053 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,06669257 0,08322734 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06669257 0,0831842 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06669257 0,08314109 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06669257 0,08309804 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06669257 0,08305503 ! telomere organization GO:0032200 43 25 0,000 0,06669257 0,08301206 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06669257 0,08296914 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06669257 0,08292626 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06926682 0,08608263 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06926682 0,08603819 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06926682 0,08599379 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06926682 0,08594944 ! initiation of viral infection GO:0019059 57 26 0,000 0,06926682 0,08590514 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06926682 0,08586088 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06926682 0,08581667 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06926682 0,0857725 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06926682 0,08572838 ! molting cycle process GO:0022404 50 26 0,000 0,06926682 0,08568431 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06926682 0,08564027 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06926682 0,08559629 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06926682 0,08555235 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06926682 0,08550845 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06926682 0,0854646 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06926682 0,0854208 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06926682 0,08537704 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06926682 0,08533332 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06926682 0,08528965 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06926682 0,08524602 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06926682 0,08520244 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06926682 0,0851589 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06926682 0,08511541 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06926682 0,08507196 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06926682 0,08502856 ! neuron fate commitment GO:0048663 48 27 0,000 0,07183406 0,08813501 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,07183406 0,08809009 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07183406 0,08804521 ! iron ion transport GO:0006826 59 27 0,000 0,07183406 0,08800038 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07183406 0,0879556 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07183406 0,08791086 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07183406 0,08786617 ! fat cell differentiation GO:0045444 50 27 0,000 0,07183406 0,08782152 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07183406 0,08777692 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07183406 0,08773236 ! autophagy GO:0006914 41 27 0,000 0,07183406 0,08768785 ! male gonad development GO:0008584 44 27 0,000 0,07183406 0,08764339 ! primary neural tube formation GO:0014020 51 27 0,000 0,07183406 0,08759896 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07183406 0,08755459 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07183406 0,08751026 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07183406 0,08746597 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07183406 0,08742173 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07183406 0,08737753 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07183406 0,08733338 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07183406 0,08728927 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07439431 0,09035472 ! circadian rhythm GO:0007623 50 28 0,000 0,07439431 0,09030913 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07439431 0,09026359 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07439431 0,0902181 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07439431 0,09017265 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07439431 0,09012724 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07439431 0,09008188 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07439431 0,09003657 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07439431 0,0899913 ! synaptogenesis GO:0007416 42 28 0,000 0,07439431 0,08994608 ! lipid oxidation GO:0034440 43 28 0,000 0,07439431 0,08990091 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07439431 0,08985578 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07439431 0,08981069 ! translational initiation GO:0006413 65 29 0,000 0,07694758 0,09284647 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07694758 0,09279993 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07694758 0,09275344 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07694758 0,09270699 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07694758 0,09266059 ! catechol metabolic process GO:0009712 54 29 0,000 0,07694758 0,09261424 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07694758 0,09256793 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07694758 0,09252167 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07694758 0,09247546 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07694758 0,09242929 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07694758 0,09238317 ! cell fate determination GO:0001709 60 29 0,000 0,07694758 0,09233709 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07694758 0,09229106 ! detection of light stimulus GO:0009583 38 29 0,000 0,07694758 0,09224508 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07694758 0,09219914 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07694758 0,09215324 ! regulation of coagulation GO:0050818 46 29 0,000 0,07694758 0,0921074 ! phenol metabolic process GO:0018958 55 30 0,000 0,07949389 0,09510805 ! zinc ion transport GO:0006829 45 30 0,000 0,07949389 0,09506078 ! membrane docking GO:0022406 61 30 0,000 0,07949389 0,09501356 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07949389 0,09496638 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07949389 0,09491925 ! acute-phase response GO:0006953 49 30 0,000 0,07949389 0,09487217 ! myofibril assembly GO:0030239 47 30 0,000 0,07949389 0,09482513 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07949389 0,09477814 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07949389 0,0947312 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07949389 0,0946843 ! phospholipid transport GO:0015914 51 30 0,000 0,07949389 0,09463745 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07949389 0,09459065 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07949389 0,09454389 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07949389 0,09449718 ! eye morphogenesis GO:0048592 60 30 0,000 0,07949389 0,09445051 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08203325 0,09741955 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08203325 0,09737149 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08203325 0,09732348 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08203325 0,09727551 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08203325 0,09722759 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08203325 0,09717972 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08203325 0,09713189 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08203325 0,09708412 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08203325 0,09703639 ! ovulation cycle process GO:0022602 49 31 0,000 0,08203325 0,0969887 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08203325 0,09694107 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08203325 0,09689348 ! peptide transport GO:0015833 55 31 0,000 0,08203325 0,09684593 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08203325 0,09679844 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08203325 0,09675099 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08203325 0,09670358 ! mesoderm formation GO:0001707 69 31 0,000 0,08203325 0,09665622 ! natural killer cell activation GO:0030101 45 31 0,000 0,08203325 0,09660891 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08203325 0,09656165 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08203325 0,09651443 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08203325 0,09646726 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08203325 0,09642013 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0845657 0,09934818 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0845657 0,0992997 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0845657 0,09925126 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0845657 0,09920287 ! cholesterol transport GO:0030301 56 32 0,000 0,0845657 0,09915452 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0845657 0,09910623 ! spliceosome assembly GO:0000245 67 32 0,000 0,0845657 0,09905798 ! spindle organization GO:0007051 46 32 0,000 0,0845657 0,09900977 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0845657 0,09896162 ! metanephros development GO:0001656 74 32 0,000 0,0845657 0,09891351 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0845657 0,09886544 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0845657 0,09881743 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0845657 0,09876946 ! muscle cell development GO:0055001 49 32 0,000 0,0845657 0,09872153 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0845657 0,09867366 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0845657 0,09862583 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0845657 0,09857804 ! ovulation cycle GO:0042698 51 32 0,000 0,0845657 0,09853031 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0845657 0,09848261 ! hindbrain development GO:0030902 61 32 0,000 0,0845657 0,09843497 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0845657 0,09838737 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0845657 0,09833982 ! gene silencing GO:0016458 65 32 0,000 0,0845657 0,09829231 ! post-embryonic development GO:0009791 69 33 0,000 0,08709125 0,10117892 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08709125 0,10113009 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08709125 0,1010813 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08709125 0,10103257 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08709125 0,10098388 ! sterol transport GO:0015918 57 33 0,000 0,08709125 0,10093523 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08709125 0,10088664 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08709125 0,10083809 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08960991 0,1037044 ! glial cell differentiation GO:0010001 63 34 0,000 0,08960991 0,10365454 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08960991 0,10360473 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08960991 0,10355497 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08960991 0,10350525 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08960991 0,10345559 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08960991 0,10340597 ! mismatch repair GO:0006298 46 34 0,000 0,08960991 0,1033564 ! spermatid development GO:0007286 63 34 0,000 0,08960991 0,10330687 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08960991 0,1032574 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08960991 0,10320797 ! placenta development GO:0001890 53 34 0,000 0,08960991 0,10315859 ! regulation of muscle development GO:0048634 70 35 0,000 0,09212171 0,10599944 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,09212171 0,10594877 ! negative regulation of secretion GO:0051048 63 35 0,000 0,09212171 0,10589815 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09212171 0,10584758 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,09212171 0,10579705 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,09212171 0,10574658 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,09212171 0,10569615 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,09212171 0,10564577 ! cytokine production GO:0001816 59 35 0,000 0,09212171 0,10559544 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,09212171 0,10554516 ! neural tube formation GO:0001841 67 35 0,000 0,09212171 0,10549492 ! vesicle localization GO:0051648 64 35 0,000 0,09212171 0,10544473 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09462666 0,10826045 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09462666 0,108209 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09462666 0,10815759 ! positive regulation of cell development GO:0010720 80 36 0,000 0,09462666 0,10810624 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09462666 0,10805493 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09462666 0,10800367 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09462666 0,10795246 ! aerobic respiration GO:0009060 55 36 0,000 0,09462666 0,1079013 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,09462666 0,10785018 ! embryonic organ development GO:0048568 57 36 0,000 0,09462666 0,10779912 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,09462666 0,1077481 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09712478 0,11054031 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09712478 0,11048805 ! meiosis I GO:0007127 65 37 0,000 0,09712478 0,11043583 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09712478 0,11038366 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09712478 0,11033155 ! tissue remodeling GO:0048771 76 37 0,000 0,09712478 0,11027948 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09712478 0,11022746 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09712478 0,11017549 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09712478 0,11012357 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,09712478 0,1100717 ! pigment metabolic process GO:0042440 80 37 0,000 0,09712478 0,11001988 ! spermatid differentiation GO:0048515 66 37 0,000 0,09712478 0,1099681 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09961609 0,1127358 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09961609 0,1126828 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,09961609 0,11262985 ! nucleus organization GO:0006997 67 38 0,000 0,09961609 0,11257694 ! lipid homeostasis GO:0055088 67 38 0,000 0,09961609 0,11252409 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,09961609 0,11247129 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,09961609 0,11241853 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09961609 0,11236583 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09961609 0,11231317 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,09961609 0,11226057 ! glucan metabolic process GO:0044042 62 38 0,000 0,09961609 0,11220801 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,10210061 0,11495277 ! learning GO:0007612 77 39 0,000 0,10210061 0,114899 ! ear morphogenesis GO:0042471 60 39 0,000 0,10210061 0,11484529 ! organic ether metabolic process GO:0018904 55 39 0,000 0,10210061 0,11479162 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10210061 0,114738 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10210061 0,11468444 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,10210061 0,11463092 ! RNA modification GO:0009451 57 39 0,000 0,10210061 0,11457746 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,10457836 0,11730327 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,10457836 0,11724861 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,10457836 0,117194 ! feeding behavior GO:0007631 59 40 0,000 0,10457836 0,11713944 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,10457836 0,11708493 ! mesenchymal cell development GO:0014031 87 40 0,000 0,10457836 0,11703048 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,10457836 0,11697607 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10704935 0,11968435 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10704935 0,11962876 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,10704935 0,11957323 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10704935 0,11951774 ! gliogenesis GO:0042063 88 41 0,000 0,10704935 0,1194623 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,10704935 0,11940692 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,10704935 0,11935159 ! polyol metabolic process GO:0019751 66 41 0,000 0,10704935 0,11929631 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10704935 0,11924108 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1095136 0,12192953 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,1095136 0,12187314 ! regulation of tube size GO:0035150 71 42 0,000 0,1095136 0,12181679 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1095136 0,1217605 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1095136 0,12170426 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1095136 0,12164807 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1095136 0,12159193 ! neuron migration GO:0001764 79 42 0,000 0,1095136 0,12153585 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1095136 0,12147982 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,1095136 0,12142384 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11197114 0,12409146 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,11197114 0,12403432 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11197114 0,12397724 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,11197114 0,12392022 ! glucose transport GO:0015758 65 43 0,000 0,11197114 0,12386324 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11197114 0,12380632 ! neural tube development GO:0021915 77 43 0,000 0,11197114 0,12374945 ! striated muscle contraction GO:0006941 77 43 0,000 0,11197114 0,12369263 ! phagocytosis GO:0006909 90 43 0,000 0,11197114 0,12363587 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11197114 0,12357915 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,11442197 0,12622616 ! hexose transport GO:0008645 67 44 0,000 0,11442197 0,12616831 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,11442197 0,12611052 ! biopolymer methylation GO:0043414 84 44 0,000 0,11442197 0,12605277 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,11442197 0,12599508 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,11442197 0,12593745 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11686612 0,12856877 ! glycolysis GO:0006096 65 45 0,000 0,11686612 0,12851 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11686612 0,1284513 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11686612 0,12839264 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11686612 0,12833404 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11686612 0,1282755 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11686612 0,128217 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11686612 0,12815856 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11686612 0,12810018 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,11686612 0,12804184 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11930361 0,13065293 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,11930361 0,13059349 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11930361 0,1305341 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,12173445 0,13313322 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12173445 0,13307273 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,12173445 0,1330123 ! JNK cascade GO:0007254 91 47 0,000 0,12173445 0,13295192 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,12173445 0,1328916 ! methylation GO:0032259 90 47 0,000 0,12173445 0,13283133 ! protein homooligomerization GO:0051260 76 47 0,000 0,12173445 0,13277112 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12415866 0,13535376 ! cellular component disassembly GO:0022411 86 48 0,000 0,12415866 0,13529245 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,12415866 0,13523121 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,12415866 0,13517002 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12415866 0,13510888 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,12415866 0,1350478 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,12657626 0,13761522 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,12657626 0,13755306 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,12657626 0,13749096 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,12657626 0,13742892 ! endocrine system development GO:0035270 104 49 0,000 0,12657626 0,13736693 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,12657626 0,137305 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,12657626 0,13724312 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,12657626 0,1371813 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,12898727 0,13973137 ! regulation of ossification GO:0030278 117 50 0,000 0,12898727 0,13966848 ! inner ear development GO:0048839 79 50 0,000 0,12898727 0,13960565 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12898727 0,13954288 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12898727 0,13948017 ! viral infectious cycle GO:0019058 99 51 0,000 0,1313917 0,14201637 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1313917 0,1419526 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1313917 0,14188888 ! excretion GO:0007588 83 51 0,000 0,1313917 0,14182523 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1313917 0,14176163 ! chromatin remodeling GO:0006338 109 51 0,000 0,1313917 0,14169809 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1313917 0,1416346 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1313917 0,14157117 ! vesicle organization GO:0016050 107 51 0,000 0,1313917 0,1415078 ! regulation of cell shape GO:0008360 125 51 0,000 0,1313917 0,14144449 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,1313917 0,14138123 ! membrane fusion GO:0006944 110 52 0,000 0,13378958 0,14389706 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,13378958 0,14383276 ! amino acid activation GO:0043038 92 52 0,000 0,13378958 0,14376852 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,13618091 0,14627289 ! RNA catabolic process GO:0006401 93 53 0,000 0,13618091 0,14620762 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,13618091 0,1461424 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,13618091 0,14607725 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,13618091 0,14601215 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,13618091 0,14594711 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,13856572 0,14843683 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,13856572 0,14837077 ! cell recognition GO:0008037 85 54 0,000 0,13856572 0,14830477 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,13856572 0,14823883 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,13856572 0,14817294 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,13856572 0,14810712 ! chloride transport GO:0006821 90 55 0,000 0,14094403 0,1505823 ! glucose catabolic process GO:0006007 82 55 0,000 0,14094403 0,15051546 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,14094403 0,15044868 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,14094403 0,15038197 ! gastrulation GO:0007369 112 55 0,000 0,14094403 0,15031531 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,14094403 0,15024871 ! RNA elongation GO:0006354 79 55 0,000 0,14094403 0,15018217 ! nuclear export GO:0051168 97 55 0,000 0,14094403 0,15011568 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,14094403 0,15004926 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14331585 0,15250682 ! sensory perception of smell GO:0007608 80 56 0,000 0,14331585 0,1524394 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14331585 0,15237204 ! proton transport GO:0015992 94 56 0,000 0,14331585 0,15230474 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,14331585 0,1522375 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,1456812 0,1546818 ! hydrogen transport GO:0006818 97 58 0,000 0,1480401 0,1571171 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,1480401 0,15704783 ! regulation of endocytosis GO:0030100 91 58 0,000 0,1480401 0,15697861 ! positive regulation of secretion GO:0051047 95 59 0,000 0,15039256 0,15940286 ! regulation of cellular component size GO:0032535 109 59 0,000 0,15039256 0,15933267 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,15039256 0,15926254 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,15039256 0,15919247 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,15039256 0,15912247 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,15039256 0,15905253 ! establishment of organelle localization GO:0051656 109 59 0,000 0,15039256 0,15898264 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1527386 0,16139178 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1527386 0,16132093 ! camera-type eye development GO:0043010 116 60 0,000 0,1527386 0,16125014 ! kidney development GO:0001822 122 60 0,000 0,1527386 0,16117942 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,15507825 0,16357662 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,15507825 0,16350494 ! mesoderm development GO:0007498 119 61 0,000 0,15507825 0,16343332 ! tRNA processing GO:0008033 89 61 0,000 0,15507825 0,16336176 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,15507825 0,16329027 ! ear development GO:0043583 103 62 0,000 0,15741151 0,16567458 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,15741151 0,16560214 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,15741151 0,16552976 ! regulation of mitosis GO:0007088 105 63 0,000 0,1597384 0,16790328 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1597384 0,16782996 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,1597384 0,1677567 ! detection of external stimulus GO:0009581 91 63 0,000 0,1597384 0,16768351 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,1597384 0,16761038 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,16205895 0,16997116 ! cell redox homeostasis GO:0045454 102 64 0,000 0,16205895 0,1698971 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,16205895 0,1698231 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,16205895 0,16974917 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,16205895 0,1696753 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,16437317 0,17202342 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,16437317 0,17194863 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,16437317 0,1718739 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,16437317 0,17179923 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,16668107 0,17413576 ! secondary metabolic process GO:0019748 116 66 0,000 0,16668107 0,17406018 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,16898267 0,17638712 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,16898267 0,17631063 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,16898267 0,1762342 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,16898267 0,17615784 ! hexose catabolic process GO:0019320 104 67 0,000 0,16898267 0,17608155 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,16898267 0,17600533 ! adaptive immune response GO:0002250 119 67 0,000 0,16898267 0,17592917 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,16898267 0,17585307 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,17127799 0,17816466 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,17127799 0,17808766 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,17127799 0,17801073 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,17127799 0,17793387 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,17356705 0,18023406 ! urogenital system development GO:0001655 137 69 0,000 0,17356705 0,18015631 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,17356705 0,18007862 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,17356705 0,180001 ! antigen processing and presentation GO:0019882 104 69 0,000 0,17356705 0,17992345 ! appendage morphogenesis GO:0035107 135 70 0,000 0,17584986 0,18221136 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,17812645 0,18449084 ! appendage development GO:0048736 136 71 0,000 0,17812645 0,18441146 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,17812645 0,18433214 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,17812645 0,18425289 ! regulation of immune effector process GO:0002697 137 71 0,000 0,17812645 0,18417371 ! acute inflammatory response GO:0002526 113 72 0,000 0,18039681 0,18644104 ! carbohydrate transport GO:0008643 110 72 0,000 0,18039681 0,18636099 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,18039681 0,186281 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,18039681 0,18620109 ! learning or memory GO:0007611 147 73 0,000 0,18266099 0,18845726 ! regulation of blood pressure GO:0008217 125 73 0,000 0,18266099 0,18837648 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,18266099 0,18829577 ! fertilization GO:0009566 90 73 0,000 0,18266099 0,18821513 ! transition metal ion transport GO:0000041 126 74 0,000 0,18491898 0,19046022 ! neurotransmitter transport GO:0006836 123 74 0,000 0,18491898 0,19037872 ! exocytosis GO:0006887 133 74 0,000 0,18491898 0,19029729 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,18491898 0,19021593 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,18491898 0,19013464 ! eye development GO:0001654 143 74 0,000 0,18491898 0,19005342 ! organelle localization GO:0051640 136 74 0,000 0,18491898 0,18997227 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,18717081 0,19220357 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,18717081 0,19212157 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,18717081 0,19203964 ! rhythmic process GO:0048511 128 75 0,000 0,18717081 0,19195779 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,18941649 0,19417813 ! defense response to bacterium GO:0042742 89 76 0,000 0,18941649 0,19409544 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,18941649 0,19401281 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,18941649 0,19393025 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,19165605 0,19613971 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,19165605 0,19605631 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,19165605 0,19597299 ! blood coagulation GO:0007596 146 78 0,000 0,19388949 0,19817252 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,19388949 0,19808837 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,19388949 0,19800429 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,19611683 0,20019393 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,19611683 0,20010903 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,19611683 0,2000242 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,19611683 0,19993945 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,19611683 0,19985476 ! muscle cell differentiation GO:0042692 159 80 0,000 0,19833809 0,20203279 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,19833809 0,20194729 ! inorganic anion transport GO:0015698 138 80 0,000 0,19833809 0,20186187 ! digestion GO:0007586 112 81 0,000 0,20055329 0,20403012 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,20055329 0,20394388 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,20055329 0,20385772 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,20276244 0,20601623 ! hemostasis GO:0007599 158 84 0,000 0,20716267 0,21039822 ! regulation of ligase activity GO:0051340 142 84 0,000 0,20716267 0,21030944 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,20716267 0,21022074 ! nucleosome assembly GO:0006334 122 85 0,000 0,20935378 0,21235463 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,20935378 0,21226514 ! amine biosynthetic process GO:0009309 138 86 0,000 0,2115389 0,21439031 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,2115389 0,21430004 ! chromatin assembly GO:0031497 124 86 0,000 0,2115389 0,21420985 ! tube morphogenesis GO:0035239 176 86 0,000 0,2115389 0,21411973 ! alcohol catabolic process GO:0046164 130 86 0,000 0,2115389 0,21402969 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,21371806 0,21614361 ! cellular respiration GO:0045333 135 88 0,000 0,21589126 0,21824974 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,21589126 0,21815808 ! cellular defense response GO:0006968 114 89 0,000 0,21805854 0,2202556 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,21805854 0,22016317 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,22021989 0,22225212 ! sterol metabolic process GO:0016125 152 91 0,000 0,22237534 0,22433336 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,22237534 0,22423934 ! nucleosome organization GO:0034728 138 92 0,000 0,22452491 0,22631208 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,22452491 0,22621731 ! vitamin metabolic process GO:0006766 139 92 0,000 0,22452491 0,22612262 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2266686 0,22818605 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,2266686 0,22809061 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,2266686 0,22799526 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,22880644 0,23004944 ! female pregnancy GO:0007565 164 94 0,000 0,22880644 0,22995334 ! transcription initiation GO:0006352 153 94 0,000 0,22880644 0,22985733 ! forebrain development GO:0030900 188 95 0,000 0,23093844 0,23190229 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,23093844 0,23180555 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,23306462 0,23384215 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,23306462 0,23374468 ! detection of stimulus GO:0051606 151 96 0,000 0,23306462 0,23364728 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,23518499 0,23567476 ! hormone metabolic process GO:0042445 157 97 0,000 0,23518499 0,23557664 ! response to virus GO:0009615 160 98 0,000 0,23729957 0,23759582 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,23729957 0,23749699 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,23729957 0,23739824 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,23940837 0,23940837