pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6369-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mammary gland development GO:0030879 57 31 4,000 4,085E-08 9,395E-05 ! regulation of intracellular protein transport GO:0033157 59 35 4,000 7,73E-08 8,89E-05 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 4,000 1,992E-07 1,527E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 3,000 2,024E-07 1,164E-04 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 2,000 2,934E-07 1,349E-04 ! positive regulation of intracellular transport GO:0032388 29 19 3,000 3,281E-07 1,258E-04 ! regulation of intracellular transport GO:0032386 78 49 4,000 4,392E-07 1,443E-04 ! regulation of protein export from nucleus GO:0046825 6 6 2,000 5,854E-07 1,683E-04 ! ER overload response GO:0006983 7 6 2,000 5,854E-07 1,496E-04 ! midbrain development GO:0030901 6 6 2,000 5,854E-07 1,346E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 1,632E-06 3,412E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,632E-06 3,128E-04 ! response to X-ray GO:0010165 16 10 2,000 3,481E-06 6,159E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 2,000 3,481E-06 5,719E-04 ! regulation of protein transport GO:0051223 114 76 4,000 3,99E-06 6,117E-04 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 4,000 4,257E-06 6,119E-04 ! regulation of mRNA processing GO:0050684 18 11 2,000 4,776E-06 6,462E-04 ! response to gamma radiation GO:0010332 20 12 2,000 6,354E-06 8,119E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 6,645E-06 8,043E-04 ! regulation of protein localization GO:0032880 132 85 4,000 6,933E-06 7,973E-04 ! positive regulation of protein transport GO:0051222 55 40 3,000 7,366E-06 8,067E-04 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 8,241E-06 8,616E-04 ! regulation of DNA replication GO:0006275 75 48 3,000 1,539E-05 1,539E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 2,755E-05 2,64E-03 ! embryonic limb morphogenesis GO:0030326 86 60 3,000 3,751E-05 3,451E-03 GO:0035113|embryonic appendage morphogenesis, ! cell aging GO:0007569 32 21 2,000 3,765E-05 3,33E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 3,765E-05 3,207E-03 ! protein import into nucleus, translocation GO:0000060 36 22 2,000 4,35E-05 3,573E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 4,35E-05 3,45E-03 ! protein tetramerization GO:0051262 39 22 2,000 4,35E-05 3,335E-03 ! appendage morphogenesis GO:0035107 93 64 3,000 4,842E-05 3,593E-03 GO:0035108|limb morphogenesis, ! positive regulation of cell adhesion GO:0045785 37 23 2,000 4,991E-05 3,587E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 4,991E-05 3,478E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 4,991E-05 3,376E-03 ! negative regulation of DNA replication GO:0008156 35 23 2,000 4,991E-05 3,28E-03 ! appendage development GO:0048736 94 65 3,000 5,148E-05 3,289E-03 GO:0060173|limb development, ! protein oligomerization GO:0051259 100 65 3,000 5,148E-05 3,2E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 5,691E-05 3,445E-03 ! mitochondrial membrane organization GO:0007006 39 24 2,000 5,691E-05 3,356E-03 ! response to ionizing radiation GO:0010212 47 27 2,000 8,17E-05 4,698E-03 ! BMP signaling pathway GO:0030509 40 28 2,000 9,13E-05 5,122E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 9,13E-05 5E-03 ! forebrain regionalization GO:0021871 6 5 1,000 9,66E-05 5,167E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 9,66E-05 5,049E-03 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 9,66E-05 4,937E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 9,66E-05 4,83E-03 ! centrosome duplication GO:0051298 5 5 1,000 9,66E-05 4,727E-03 ! response to UV-C GO:0010225 6 5 1,000 9,66E-05 4,629E-03 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 9,66E-05 4,534E-03 ! negative regulation of multicellular organism growth GO:0040015 7 5 1,000 9,66E-05 4,443E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 9,66E-05 4,356E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 9,66E-05 4,273E-03 GO:0007439|ectodermal gut development, ! positive regulation of actin filament bundle formation GO:0032233 12 5 1,000 9,66E-05 4,192E-03 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 1,016E-04 4,328E-03 ! hindbrain development GO:0030902 45 30 2,000 1,126E-04 4,711E-03 ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 1,37E-04 5,627E-03 ! regulation of helicase activity GO:0051095 11 6 1,000 1,446E-04 5,835E-03 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 1,446E-04 5,734E-03 ! male meiosis GO:0007140 7 6 1,000 1,446E-04 5,637E-03 ! amyloid precursor protein catabolic process GO:0042987 9 6 1,000 1,446E-04 5,543E-03 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 1,000 1,446E-04 5,452E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,446E-04 5,364E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 1,446E-04 5,279E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! neuron apoptosis GO:0051402 8 6 1,000 1,446E-04 5,197E-03 ! male sex determination GO:0030238 9 6 1,000 1,446E-04 5,117E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 1,446E-04 5,039E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 1,446E-04 4,964E-03 ! blastocyst growth GO:0001832 15 6 1,000 1,446E-04 4,891E-03 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 1,469E-04 4,898E-03 ! anterior/posterior pattern formation GO:0009952 124 85 3,000 1,469E-04 4,828E-03 ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 1,608E-04 5,209E-03 ! dorsal/ventral pattern formation GO:0009953 44 34 2,000 1,646E-04 5,256E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,646E-04 5,184E-03 ! glycogen metabolic process GO:0005977 48 35 2,000 1,796E-04 5,581E-03 ! neural tube development GO:0021915 50 36 2,000 1,955E-04 5,994E-03 ! glucan metabolic process GO:0044042 49 36 2,000 1,955E-04 5,915E-03 GO:0006073|cellular glucan metabolic process, ! cell fate commitment GO:0045165 141 92 3,000 1,995E-04 5,959E-03 ! actin-myosin filament sliding GO:0033275 10 7 1,000 2,02E-04 5,957E-03 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! positive regulation of heart rate GO:0010460 9 7 1,000 2,02E-04 5,882E-03 ! spinal cord patterning GO:0021511 7 7 1,000 2,02E-04 5,809E-03 ! Rac protein signal transduction GO:0016601 7 7 1,000 2,02E-04 5,737E-03 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 2,02E-04 5,667E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 2,02E-04 5,599E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 2,02E-04 5,532E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 1,000 2,02E-04 5,467E-03 ! B cell lineage commitment GO:0002326 17 7 1,000 2,02E-04 5,403E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 1,000 2,02E-04 5,341E-03 ! mast cell activation GO:0045576 9 7 1,000 2,02E-04 5,28E-03 ! spinal cord motor neuron differentiation GO:0021522 9 7 1,000 2,02E-04 5,221E-03 ! T cell lineage commitment GO:0002360 12 7 1,000 2,02E-04 5,163E-03 ! response to tumor cell GO:0002347 12 7 1,000 2,02E-04 5,106E-03 ! positive regulation of ATPase activity GO:0032781 10 7 1,000 2,02E-04 5,051E-03 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 2,000 2,299E-04 5,686E-03 ! in utero embryonic development GO:0001701 147 96 3,000 2,35E-04 5,75E-03 ! developmental growth GO:0048589 62 39 2,000 2,485E-04 6,017E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 2,681E-04 6,423E-03 ! double-strand break repair GO:0006302 67 40 2,000 2,681E-04 6,357E-03 ! smoothened signaling pathway GO:0007224 8 8 1,000 2,688E-04 6,309E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 2,688E-04 6,246E-03 ! amyloid precursor protein metabolic process GO:0042982 12 8 1,000 2,688E-04 6,183E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,688E-04 6,122E-03 ! multicellular organism growth GO:0035264 14 8 1,000 2,688E-04 6,062E-03 ! ruffle organization GO:0031529 11 8 1,000 2,688E-04 6,003E-03 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 2,688E-04 5,945E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 2,688E-04 5,889E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 2,688E-04 5,833E-03 ! energy reserve metabolic process GO:0006112 59 41 2,000 2,886E-04 6,204E-03 ! mitochondrial transport GO:0006839 60 42 2,000 3,101E-04 6,604E-03 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 3,326E-04 7,019E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 3,326E-04 6,955E-03 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 3,326E-04 6,892E-03 ! regulation of developmental growth GO:0048638 13 9 1,000 3,449E-04 7,084E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 3,449E-04 7,021E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 3,449E-04 6,959E-03 ! ventral spinal cord development GO:0021517 11 9 1,000 3,449E-04 6,899E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 3,449E-04 6,839E-03 ! motor axon guidance GO:0008045 14 9 1,000 3,449E-04 6,781E-03 ! positive regulation of phagocytosis GO:0050766 11 9 1,000 3,449E-04 6,724E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 1,000 3,449E-04 6,667E-03 ! mRNA cleavage GO:0006379 13 9 1,000 3,449E-04 6,612E-03 ! oocyte differentiation GO:0009994 12 9 1,000 3,449E-04 6,557E-03 GO:0048599|oocyte development, ! cell maturation GO:0048469 60 45 2,000 3,808E-04 7,178E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 3,808E-04 7,12E-03 ! regulation of ossification GO:0030278 71 46 2,000 4,064E-04 7,539E-03 ! response to UV GO:0009411 75 46 2,000 4,064E-04 7,478E-03 ! neuron fate specification GO:0048665 11 10 1,000 4,303E-04 7,855E-03 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 4,303E-04 7,793E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 4,303E-04 7,732E-03 ! positive regulation of heart contraction GO:0045823 14 10 1,000 4,303E-04 7,672E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 4,303E-04 7,613E-03 ! negative regulation of ossification GO:0030279 19 10 1,000 4,303E-04 7,555E-03 ! cranial nerve development GO:0021545 12 10 1,000 4,303E-04 7,498E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 4,303E-04 7,442E-03 GO:0043470|regulation of carbohydrate catabolic process, ! embryonic gut development GO:0048566 11 10 1,000 4,303E-04 7,386E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 4,303E-04 7,331E-03 ! cellular polysaccharide metabolic process GO:0044264 63 48 2,000 4,61E-04 7,797E-03 ! gastrulation GO:0007369 73 48 2,000 4,61E-04 7,74E-03 ! heart morphogenesis GO:0003007 65 48 2,000 4,61E-04 7,684E-03 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 5,249E-04 8,685E-03 ! virus-host interaction GO:0019048 17 11 1,000 5,249E-04 8,623E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 5,249E-04 8,562E-03 GO:0000725|recombinational repair, ! regulation of intracellular pH GO:0051453 17 11 1,000 5,249E-04 8,502E-03 ! membrane protein proteolysis GO:0033619 18 11 1,000 5,249E-04 8,442E-03 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of phagocytosis GO:0050764 14 11 1,000 5,249E-04 8,383E-03 ! digestive tract morphogenesis GO:0048546 15 11 1,000 5,249E-04 8,326E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 5,249E-04 8,269E-03 GO:0042130|negative regulation of T cell proliferation, ! aging GO:0007568 79 52 2,000 5,839E-04 9,135E-03 ! nucleotide-excision repair GO:0006289 64 52 2,000 5,839E-04 9,074E-03 ! regulation of bone remodeling GO:0046850 90 53 2,000 6,175E-04 9,532E-03 ! positive regulation of blood pressure GO:0045777 16 12 1,000 6,286E-04 9,638E-03 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 6,286E-04 9,574E-03 ! glycoprotein catabolic process GO:0006516 19 12 1,000 6,286E-04 9,511E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 6,286E-04 9,449E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! gastrulation with mouth forming second GO:0001702 15 12 1,000 6,286E-04 9,388E-03 ! regulation of tissue remodeling GO:0034103 91 54 2,000 6,524E-04 9,681E-03 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 7,259E-04 0,01070176 ! cell differentiation in spinal cord GO:0021515 16 13 1,000 7,414E-04 0,0108609 ! regulation of cellular pH GO:0030641 20 13 1,000 7,414E-04 0,01079216 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 7,645E-04 0,01105858 ! developmental maturation GO:0021700 75 57 2,000 7,645E-04 0,01098946 ! neuron maturation GO:0042551 21 14 1,000 8,632E-04 0,01233132 ! regulation of S phase GO:0033261 18 14 1,000 8,632E-04 0,0122552 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 8,632E-04 0,01218002 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 8,632E-04 0,01210575 ! cardiac muscle contraction GO:0060048 23 14 1,000 8,632E-04 0,01203238 ! cellular response to starvation GO:0009267 21 14 1,000 8,632E-04 0,0119599 ! regulation of heart rate GO:0002027 23 14 1,000 8,632E-04 0,01188828 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 8,632E-04 0,01181752 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 8,632E-04 0,01174759 ! G1/S transition checkpoint GO:0031575 33 14 1,000 8,632E-04 0,01167849 ! regulation of ATPase activity GO:0043462 18 14 1,000 8,632E-04 0,01161019 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 8,632E-04 0,01154269 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 8,632E-04 0,01147597 ! lipid phosphorylation GO:0046834 23 15 1,000 9,94E-04 0,01313886 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 9,94E-04 0,01306378 ! centrosome cycle GO:0007098 16 15 1,000 9,94E-04 0,01298955 ! regulation of survival gene product expression GO:0045884 20 15 1,000 9,94E-04 0,01291617 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 9,94E-04 0,0128436 ! embryonic digit morphogenesis GO:0042733 18 15 1,000 9,94E-04 0,01277185 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 9,94E-04 0,0127009 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 9,94E-04 0,01263073 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 9,94E-04 0,01256133 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 9,94E-04 0,01249268 ! defense response to virus GO:0051607 27 15 1,000 9,94E-04 0,01242479 ! regulation of caspase activity GO:0043281 97 65 2,000 1,121E-03 0,01393861 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,134E-03 0,01401876 ! oogenesis GO:0048477 23 16 1,000 1,134E-03 0,01394379 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,134E-03 0,01386962 ! nerve development GO:0021675 18 16 1,000 1,134E-03 0,01379624 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 1,224E-03 0,01481865 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,282E-03 0,01544083 ! neuromuscular junction development GO:0007528 23 17 1,000 1,282E-03 0,01536041 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 1,000 1,282E-03 0,01528082 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 1,282E-03 0,01520205 ! peptidyl-serine modification GO:0018209 27 17 1,000 1,282E-03 0,01512409 ! proximal/distal pattern formation GO:0009954 25 17 1,000 1,282E-03 0,01504693 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 1,39E-03 0,01622295 ! regulation of catabolic process GO:0009894 106 70 2,000 1,39E-03 0,01614102 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,44E-03 0,01663901 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,44E-03 0,01655581 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 1,44E-03 0,01647345 ! heart process GO:0003015 27 18 1,000 1,44E-03 0,0163919 GO:0060047|heart contraction, ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,44E-03 0,01631115 ! gut development GO:0048565 26 18 1,000 1,44E-03 0,01623119 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,44E-03 0,01615201 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 1,44E-03 0,01607361 ! regulation of peptidase activity GO:0052547 106 72 2,000 1,507E-03 0,01674682 ! tube morphogenesis GO:0035239 118 73 2,000 1,568E-03 0,01734208 ! mitochondrion organization GO:0007005 104 73 2,000 1,568E-03 0,01725911 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 1,606E-03 0,01758694 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,606E-03 0,01750358 GO:0010675|regulation of cellular carbohydrate metabolic process, ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 1,606E-03 0,01742102 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 1,606E-03 0,01733923 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 1,606E-03 0,01725821 ! apoptotic nuclear changes GO:0030262 24 19 1,000 1,606E-03 0,01717794 ! response to starvation GO:0042594 30 19 1,000 1,606E-03 0,01709841 ! sex determination GO:0007530 29 19 1,000 1,606E-03 0,01701961 ! sarcomere organization GO:0045214 23 19 1,000 1,606E-03 0,01694154 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 1,606E-03 0,01686418 ! protein import into nucleus GO:0006606 118 74 2,000 1,631E-03 0,0170511 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 1,631E-03 0,01697395 ! negative regulation of growth GO:0045926 123 75 2,000 1,695E-03 0,01756258 ! nuclear import GO:0051170 121 75 2,000 1,695E-03 0,01748382 ! spinal cord development GO:0021510 31 20 1,000 1,781E-03 0,01828283 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 1,781E-03 0,01820157 ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 1,781E-03 0,01812103 ! camera-type eye morphogenesis GO:0048593 34 20 1,000 1,781E-03 0,0180412 ! actin filament-based movement GO:0030048 34 20 1,000 1,781E-03 0,01796208 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 1,964E-03 0,01972632 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 1,964E-03 0,01964056 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 1,964E-03 0,01955553 GO:0060415|muscle tissue morphogenesis, ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 1,964E-03 0,01947124 ! regulation of bone mineralization GO:0030500 29 21 1,000 1,964E-03 0,01938767 ! protein localization in nucleus GO:0034504 133 80 2,000 2,04E-03 0,02004976 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 2,156E-03 0,02110237 ! spliceosomal snRNP biogenesis GO:0000387 28 22 1,000 2,156E-03 0,02101295 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 2,156E-03 0,02092429 ! microtubule organizing center organization GO:0031023 28 22 1,000 2,156E-03 0,02083637 GO:0051297|centrosome organization, ! ureteric bud development GO:0001657 32 22 1,000 2,156E-03 0,02074919 ! blastocyst development GO:0001824 37 22 1,000 2,156E-03 0,02066274 ! ossification GO:0001503 134 82 2,000 2,189E-03 0,02089109 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 2,000 2,266E-03 0,02153719 ! neuron fate commitment GO:0048663 32 23 1,000 2,357E-03 0,02230624 ! embryonic pattern specification GO:0009880 31 23 1,000 2,357E-03 0,02221482 ! myelination GO:0042552 35 23 1,000 2,357E-03 0,02212415 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 2,357E-03 0,02203421 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,357E-03 0,021945 ! osteoblast differentiation GO:0001649 40 23 1,000 2,357E-03 0,02185652 ! interaction with host GO:0051701 37 23 1,000 2,357E-03 0,02176874 ! regulation of biomineral formation GO:0070167 31 23 1,000 2,357E-03 0,02168166 ! cellular response to oxidative stress GO:0034599 33 23 1,000 2,357E-03 0,02159528 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 1,000 2,357E-03 0,02150959 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 2,425E-03 0,02204752 ! regulation of membrane potential GO:0042391 128 85 2,000 2,425E-03 0,02196072 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 2,425E-03 0,0218746 ! cell cycle arrest GO:0007050 150 86 2,000 2,507E-03 0,02252678 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,566E-03 0,02296219 ! negative regulation of cell development GO:0010721 56 24 1,000 2,566E-03 0,02287319 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 2,566E-03 0,02278487 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 2,566E-03 0,02269724 ! protein processing GO:0016485 114 88 2,000 2,677E-03 0,02358738 ! reproductive developmental process GO:0003006 127 89 2,000 2,764E-03 0,02426326 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,783E-03 0,02434042 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 2,783E-03 0,02424822 ! regulation of pH GO:0006885 36 26 1,000 3,009E-03 0,02611714 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 3,13E-03 0,02706733 ! polysaccharide metabolic process GO:0005976 129 93 2,000 3,13E-03 0,02696595 ! acute-phase response GO:0006953 42 27 1,000 3,243E-03 0,02783468 ! myofibril assembly GO:0030239 36 27 1,000 3,243E-03 0,0277312 GO:0055002|striated muscle cell development, ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 3,243E-03 0,0276285 ! negative regulation of protein transport GO:0051224 49 27 1,000 3,243E-03 0,02752654 ! protein maturation GO:0051604 129 96 2,000 3,424E-03 0,02895256 ! response to light stimulus GO:0009416 153 96 2,000 3,424E-03 0,02884651 ! positive regulation of endocytosis GO:0045807 33 28 1,000 3,486E-03 0,02926045 ! response to organic cyclic substance GO:0014070 47 28 1,000 3,486E-03 0,02915405 ! regulation of systemic arterial blood pressure GO:0003073 47 28 1,000 3,486E-03 0,02904842 ! mesoderm formation GO:0001707 46 28 1,000 3,486E-03 0,02894355 ! ensheathment of neurons GO:0007272 43 28 1,000 3,486E-03 0,02883944 GO:0008366|axon ensheathment, ! myeloid leukocyte activation GO:0002274 39 28 1,000 3,486E-03 0,02873607 ! neural tube formation GO:0001841 41 28 1,000 3,486E-03 0,02863344 ! protein import GO:0017038 156 99 2,000 3,734E-03 0,03056182 ! muscle cell development GO:0055001 38 29 1,000 3,736E-03 0,03047494 ! formation of primary germ layer GO:0001704 48 29 1,000 3,736E-03 0,03036725 ! telencephalon development GO:0021537 52 29 1,000 3,736E-03 0,03026032 ! eye morphogenesis GO:0048592 51 29 1,000 3,736E-03 0,03015415 ! tissue homeostasis GO:0001894 42 29 1,000 3,736E-03 0,03004871 GO:0048871|multicellular organismal homeostasis, ! protein localization in organelle GO:0033365 161 100 2,000 3,841E-03 0,03078023 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 3,995E-03 0,03190722 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 3,995E-03 0,03179681 ! negative regulation of cell activation GO:0050866 44 30 1,000 3,995E-03 0,03168717 ! DNA damage checkpoint GO:0000077 53 31 1,000 4,262E-03 0,03368826 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 4,262E-03 0,03357289 ! odontogenesis GO:0042476 50 31 1,000 4,262E-03 0,03345831 ! mesoderm morphogenesis GO:0048332 49 31 1,000 4,262E-03 0,03334451 ! metanephros development GO:0001656 58 31 1,000 4,262E-03 0,03323147 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 4,262E-03 0,0331192 ! cell fate specification GO:0001708 37 31 1,000 4,262E-03 0,03300769 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 4,537E-03 0,03501956 ! peripheral nervous system development GO:0007422 53 32 1,000 4,537E-03 0,03490244 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 4,537E-03 0,0347861 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4,82E-03 0,03683321 ! actomyosin structure organization GO:0031032 43 33 1,000 4,82E-03 0,03671125 ! carbohydrate homeostasis GO:0033500 39 33 1,000 4,82E-03 0,03659009 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 4,82E-03 0,03646973 ! female gonad development GO:0008585 49 33 1,000 4,82E-03 0,03635015 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 4,82E-03 0,03623136 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 4,82E-03 0,03611335 ! cytokinesis GO:0000910 52 33 1,000 4,82E-03 0,03599609 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 5,111E-03 0,03804553 ! DNA integrity checkpoint GO:0031570 57 34 1,000 5,111E-03 0,0379228 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 5,111E-03 0,03780086 ! female gamete generation GO:0007292 43 34 1,000 5,111E-03 0,0376797 ! embryonic organ development GO:0048568 45 34 1,000 5,111E-03 0,03755932 ! Notch signaling pathway GO:0007219 56 35 1,000 5,41E-03 0,03962906 ! regulation of action potential in neuron GO:0019228 54 35 1,000 5,41E-03 0,03950325 ! protein homooligomerization GO:0051260 52 35 1,000 5,41E-03 0,03937824 ! response to reactive oxygen species GO:0000302 55 36 1,000 5,717E-03 0,04147966 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 5,717E-03 0,04134922 GO:0046660|female sex differentiation, ! striated muscle cell differentiation GO:0051146 54 38 1,000 6,354E-03 0,04581144 ! regulation of T cell proliferation GO:0042129 58 38 1,000 6,354E-03 0,04566828 ! mesenchymal cell development GO:0014031 64 38 1,000 6,354E-03 0,04552601 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 6,684E-03 0,04774189 ! chromatin remodeling GO:0006338 68 39 1,000 6,684E-03 0,04759408 ! synapse organization GO:0050808 55 39 1,000 6,684E-03 0,04744719 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 7,022E-03 0,04969088 ! T cell differentiation GO:0030217 65 40 1,000 7,022E-03 0,04953846 ! B cell differentiation GO:0030183 62 40 1,000 7,022E-03 0,04938696 ! striated muscle contraction GO:0006941 62 41 1,000 7,367E-03 0,05165755 ! regulation of T cell differentiation GO:0045580 59 41 1,000 7,367E-03 0,05150054 ! cellular component disassembly GO:0022411 64 42 1,000 7,72E-03 0,05380363 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 7,72E-03 0,05364108 ! embryonic skeletal system development GO:0048706 56 42 1,000 7,72E-03 0,05347951 ! activation of caspase activity GO:0006919 65 43 1,000 8,08E-03 0,05580777 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 8,08E-03 0,05564068 ! regulation of action potential GO:0001508 71 44 1,000 8,448E-03 0,05799979 ! negative regulation of cell migration GO:0030336 92 44 1,000 8,448E-03 0,05782717 ! regulation of inflammatory response GO:0050727 60 44 1,000 8,448E-03 0,05765558 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 8,448E-03 0,057485 ! positive regulation of cell cycle GO:0045787 77 45 1,000 8,823E-03 0,0598611 ! response to estrogen stimulus GO:0043627 74 47 1,000 9,595E-03 0,06491048 ! negative regulation of immune system process GO:0002683 73 47 1,000 9,595E-03 0,06472013 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 9,595E-03 0,06453089 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 9,595E-03 0,06434275 ! positive regulation of caspase activity GO:0043280 72 48 1,000 9,993E-03 0,06681107 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 1,000 9,993E-03 0,06661741 ! regulation of endocytosis GO:0030100 63 48 1,000 9,993E-03 0,06642487 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 9,993E-03 0,06623345 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01039698 0,06871566 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,01039698 0,06851877 ! germ cell development GO:0007281 68 49 1,000 0,01039698 0,068323 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01080851 0,07082502 ! lipid modification GO:0030258 73 50 1,000 0,01080851 0,07062381 ! positive regulation of growth GO:0045927 67 50 1,000 0,01080851 0,07042374 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,01080851 0,07022481 ! muscle fiber development GO:0048747 74 51 1,000 0,01122717 0,07273942 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,01122717 0,07253509 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,01122717 0,07233192 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,01122717 0,07212987 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,01122717 0,07192895 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,01208566 0,07721396 ! kidney development GO:0001822 90 53 1,000 0,01208566 0,07700007 ! DNA catabolic process GO:0006308 67 54 1,000 0,0125254 0,0795813 ! mesoderm development GO:0007498 76 55 1,000 0,01297208 0,08219224 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,01342564 0,08483237 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,01342564 0,08459995 ! chromosome segregation GO:0007059 83 57 1,000 0,01388605 0,08726206 ! camera-type eye development GO:0043010 88 57 1,000 0,01388605 0,08702429 ! gonad development GO:0008406 79 57 1,000 0,01388605 0,08678781 ! viral reproductive process GO:0022415 87 58 1,000 0,01435325 0,08946471 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,01435325 0,08922292 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,01435325 0,08898242 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,0148272 0,09167358 ! activation of MAPK activity GO:0000187 84 59 1,000 0,0148272 0,0914278 ! lung development GO:0030324 94 59 1,000 0,0148272 0,09118334 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01530786 0,09388822 ! regulation of heart contraction GO:0008016 91 60 1,000 0,01530786 0,09363852 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,01530786 0,09339014 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01563357 0,09512493 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01563357 0,09487394 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01563357 0,09462427 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01563357 0,09437591 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01563357 0,09412885 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01563357 0,09388309 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01563357 0,0936386 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01563357 0,09339538 ! sleep GO:0030431 11 5 0,000 0,01563357 0,09315343 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01563357 0,09291272 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01563357 0,09267325 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01563357 0,09243502 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01563357 0,09219801 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01563357 0,09196221 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 0,01563357 0,09172761 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01563357 0,0914942 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01563357 0,09126199 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01563357 0,09103094 ! cobalt ion transport GO:0006824 9 5 0,000 0,01563357 0,09080107 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01563357 0,09057235 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01563357 0,09034478 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01563357 0,09011835 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01563357 0,08989306 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01563357 0,08966888 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01563357 0,08944583 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01563357 0,08922388 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01563357 0,08900303 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01563357 0,08878326 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01563357 0,08856459 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01563357 0,08834698 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01563357 0,08813045 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01563357 0,08791497 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01563357 0,08770054 ! malate metabolic process GO:0006108 7 5 0,000 0,01563357 0,08748716 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01563357 0,08727481 ! behavioral response to pain GO:0048266 7 5 0,000 0,01563357 0,08706349 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01563357 0,08685319 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01563357 0,08664391 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01563357 0,08643563 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01563357 0,08622835 ! mating behavior GO:0007617 6 5 0,000 0,01563357 0,08602206 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01563357 0,08581676 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01563357 0,08561243 ! rhythmic behavior GO:0007622 12 5 0,000 0,01563357 0,08540908 ! copulation GO:0007620 7 5 0,000 0,01563357 0,08520669 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01563357 0,08500525 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01563357 0,08480477 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01563357 0,08460523 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01563357 0,08440663 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01563357 0,08420895 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01563357 0,0840122 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01563357 0,08381637 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01563357 0,08362145 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01563357 0,08342743 ! response to protozoan GO:0001562 9 5 0,000 0,01563357 0,08323431 ! lymph vessel development GO:0001945 7 5 0,000 0,01563357 0,08304208 ! endochondral ossification GO:0001958 12 5 0,000 0,01563357 0,08285074 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01563357 0,08266028 ! parathyroid gland development GO:0060017 8 5 0,000 0,01563357 0,08247069 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01563357 0,08228197 ! anagen GO:0042640 6 5 0,000 0,01563357 0,08209411 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01563357 0,08190711 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01563357 0,08172096 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01563357 0,08153565 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01563357 0,08135118 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01563357 0,08116754 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01563357 0,08098473 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01563357 0,08080275 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01563357 0,08062157 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01563357 0,08044121 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01563357 0,08026166 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01563357 0,0800829 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01563357 0,07990494 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01563357 0,07972777 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01563357 0,07955138 ! ovulation GO:0030728 6 5 0,000 0,01563357 0,07937577 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01563357 0,07920093 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01563357 0,07902686 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01563357 0,07885356 ! response to pH GO:0009268 9 5 0,000 0,01563357 0,07868101 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01563357 0,07850922 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01563357 0,07833817 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01563357 0,07816787 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01563357 0,07799831 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01563357 0,07782949 ! polyol catabolic process GO:0046174 7 5 0,000 0,01563357 0,07766139 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01563357 0,07749401 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01563357 0,07732736 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01563357 0,07716142 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01563357 0,07699619 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01563357 0,07683167 ! urea metabolic process GO:0019627 6 5 0,000 0,01563357 0,07666785 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01563357 0,07650473 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01563357 0,0763423 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01563357 0,07618056 ! neutrophil activation GO:0042119 5 5 0,000 0,01563357 0,0760195 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01563357 0,07585912 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01563357 0,07569942 ! response to food GO:0032094 5 5 0,000 0,01563357 0,07554038 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01563357 0,07538202 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01563357 0,07522431 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01563357 0,07506727 ! forebrain neuron development GO:0021884 7 5 0,000 0,01563357 0,07491088 ! melanosome organization GO:0032438 7 5 0,000 0,01563357 0,07475514 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01563357 0,07460005 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01563357 0,07444559 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01563357 0,07429178 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01563357 0,0741386 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01563357 0,07398605 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01563357 0,07383413 ! nucleoside transport GO:0015858 6 5 0,000 0,01563357 0,07368283 ! nucleoside salvage GO:0043174 7 5 0,000 0,01563357 0,07353215 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01563357 0,07338209 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01563357 0,07323263 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01563357 0,07308379 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01563357 0,07293554 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01563357 0,0727879 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01563357 0,07264085 ! depyrimidination GO:0045008 8 5 0,000 0,01563357 0,0724944 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01563357 0,07234854 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01563357 0,07220326 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01563357 0,07205856 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01563357 0,07191444 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01563357 0,0717709 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01563357 0,07162793 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01563357 0,07148553 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01563357 0,07134369 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01563357 0,07120242 ! monocyte differentiation GO:0030224 8 5 0,000 0,01563357 0,0710617 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01563357 0,07092154 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01563357 0,07078193 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01563357 0,07064287 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01563357 0,07050436 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01563357 0,07036638 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01563357 0,07022895 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01563357 0,07009205 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01563357 0,06995569 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01563357 0,06981985 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01563357 0,06968454 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01563357 0,06954975 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01563357 0,06941549 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01563357 0,06928174 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01563357 0,0691485 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01563357 0,06901578 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01563357 0,06888357 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01563357 0,06875186 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01563357 0,06862065 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01563357 0,06848995 ! neural tube patterning GO:0021532 6 5 0,000 0,01563357 0,06835974 ! histone demethylation GO:0016577 9 5 0,000 0,01563357 0,06823002 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01563357 0,0681008 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01563357 0,06797206 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01563357 0,06784382 ! enteric nervous system development GO:0048484 8 5 0,000 0,01563357 0,06771605 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01563357 0,06758876 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01563357 0,06746196 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01563357 0,06733562 ! transcription termination GO:0006353 8 5 0,000 0,01563357 0,06720976 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01563357 0,06708437 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01563357 0,06695945 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01563357 0,06683499 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01563357 0,06671099 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01563357 0,06658745 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01563357 0,06646437 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01563357 0,06634174 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01563357 0,06621956 ! apical protein localization GO:0045176 6 5 0,000 0,01563357 0,06609784 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01563357 0,06597655 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01563357 0,06585572 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01563357 0,06573532 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01563357 0,06561537 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01563357 0,06549585 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01563357 0,06537677 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01563357 0,06525812 ! glial cell migration GO:0008347 10 5 0,000 0,01563357 0,0651399 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01563357 0,0650221 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01563357 0,06490473 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01563357 0,06478779 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01563357 0,06467126 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01563357 0,06455516 ! neural plate development GO:0001840 6 5 0,000 0,01563357 0,06443947 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01563357 0,06432419 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01563357 0,06420933 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01563357 0,06409487 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01563357 0,06398082 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01563357 0,06386718 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01563357 0,06375394 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01563357 0,0636411 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01563357 0,06352866 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01563357 0,06341662 ! spindle assembly GO:0051225 5 5 0,000 0,01563357 0,06330497 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01563357 0,06319371 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01563357 0,06308285 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01563357 0,06297237 ! organ regeneration GO:0031100 7 5 0,000 0,01563357 0,06286228 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01563357 0,06275257 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01563357 0,06264324 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01563357 0,0625343 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01563357 0,06242573 GO:0055081|anion homeostasis, ! meiosis GO:0007126 96 61 1,000 0,01579518 0,06296172 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 1,000 0,01579518 0,06285279 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,01628911 0,06470631 ! respiratory tube development GO:0030323 99 62 1,000 0,01628911 0,06459475 ! meiotic cell cycle GO:0051321 97 62 1,000 0,01628911 0,06448357 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,01678961 0,0663507 ! viral reproduction GO:0016032 92 63 1,000 0,01678961 0,06623689 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,01729664 0,06812033 ! negative regulation of cell size GO:0045792 108 64 1,000 0,01729664 0,06800388 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,01729664 0,06788783 ! respiratory system development GO:0060541 100 64 1,000 0,01729664 0,06777218 ! reproductive structure development GO:0048608 90 65 1,000 0,01781015 0,06966554 ! B cell activation GO:0042113 104 65 1,000 0,01781015 0,06954726 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,01833009 0,07145629 ! axon guidance GO:0007411 99 66 1,000 0,01833009 0,07133538 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,01833009 0,07121488 ! tRNA transcription GO:0009304 11 6 0,000 0,01873137 0,07265118 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01873137 0,07252887 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01873137 0,07240697 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01873137 0,07228549 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01873137 0,0721644 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01873137 0,07204373 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01873137 0,07192345 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01873137 0,07180358 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01873137 0,07168411 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01873137 0,07156503 ! prostate gland development GO:0030850 9 6 0,000 0,01873137 0,07144635 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01873137 0,07132806 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01873137 0,07121016 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01873137 0,07109266 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01873137 0,07097553 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01873137 0,0708588 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01873137 0,07074245 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01873137 0,07062647 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01873137 0,07051088 ! neuron adhesion GO:0007158 9 6 0,000 0,01873137 0,07039567 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01873137 0,07028083 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01873137 0,07016637 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01873137 0,07005228 ! signal peptide processing GO:0006465 8 6 0,000 0,01873137 0,06993855 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01873137 0,0698252 ! mRNA stabilization GO:0048255 15 6 0,000 0,01873137 0,06971222 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01873137 0,0695996 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01873137 0,06948734 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01873137 0,06937544 ! opsonization GO:0008228 8 6 0,000 0,01873137 0,06926391 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01873137 0,06915273 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01873137 0,06904191 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01873137 0,06893144 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01873137 0,06882133 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01873137 0,06871156 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01873137 0,06860215 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01873137 0,06849308 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01873137 0,06838436 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01873137 0,06827599 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01873137 0,06816796 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01873137 0,06806027 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01873137 0,06795292 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01873137 0,0678459 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01873137 0,06773923 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01873137 0,06763289 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01873137 0,06752688 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01873137 0,0674212 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01873137 0,06731586 ! thymic T cell selection GO:0045061 12 6 0,000 0,01873137 0,06721084 ! protein lipoylation GO:0009249 10 6 0,000 0,01873137 0,06710615 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01873137 0,06700179 ! pigment granule organization GO:0048753 11 6 0,000 0,01873137 0,06689775 ! drug transport GO:0015893 6 6 0,000 0,01873137 0,06679403 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01873137 0,06669063 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01873137 0,06658756 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01873137 0,0664848 ! histidine metabolic process GO:0006547 6 6 0,000 0,01873137 0,06638236 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01873137 0,06628023 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01873137 0,06617842 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,01873137 0,06607692 ! adenohypophysis development GO:0021984 10 6 0,000 0,01873137 0,06597573 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01873137 0,06587485 ! hyperosmotic response GO:0006972 8 6 0,000 0,01873137 0,06577427 ! microtubule nucleation GO:0007020 10 6 0,000 0,01873137 0,06567401 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01873137 0,06557405 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01873137 0,06547439 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01873137 0,06537504 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01873137 0,06527598 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01873137 0,06517723 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01873137 0,06507878 ! response to dietary excess GO:0002021 7 6 0,000 0,01873137 0,06498062 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01873137 0,06488276 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01873137 0,06478519 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01873137 0,06468791 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01873137 0,06459093 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01873137 0,06449424 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01873137 0,06439783 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01873137 0,06430172 ! organic alcohol transport GO:0015850 9 6 0,000 0,01873137 0,06420589 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01873137 0,06411034 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01873137 0,06401508 ! carnitine transport GO:0015879 8 6 0,000 0,01873137 0,0639201 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01873137 0,06382541 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01873137 0,06373099 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01873137 0,06363685 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01873137 0,06354299 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01873137 0,06344941 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01873137 0,0633561 ! parturition GO:0007567 12 6 0,000 0,01873137 0,06326307 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01873137 0,06317031 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01873137 0,06307782 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01873137 0,0629856 ! spindle checkpoint GO:0031577 14 6 0,000 0,01873137 0,06289365 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01873137 0,06280197 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01873137 0,06271055 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01873137 0,0626194 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01873137 0,06252852 ! macrophage differentiation GO:0030225 10 6 0,000 0,01873137 0,0624379 ! astrocyte development GO:0014002 14 6 0,000 0,01873137 0,06234754 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01873137 0,06225744 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01873137 0,0621676 ! interaction with symbiont GO:0051702 8 6 0,000 0,01873137 0,06207803 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01873137 0,0619887 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01873137 0,06189964 ! eating behavior GO:0042755 6 6 0,000 0,01873137 0,06181083 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01873137 0,06172228 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01873137 0,06163398 ! response to copper ion GO:0046688 9 6 0,000 0,01873137 0,06154593 ! DNA topological change GO:0006265 8 6 0,000 0,01873137 0,06145813 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01873137 0,06137058 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01873137 0,06128329 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01873137 0,06119624 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01873137 0,06110943 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01873137 0,06102287 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01873137 0,06093656 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01873137 0,06085049 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01873137 0,06076467 ! gas homeostasis GO:0033483 11 6 0,000 0,01873137 0,06067908 ! hair follicle maturation GO:0048820 7 6 0,000 0,01873137 0,06059374 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01873137 0,06050864 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01873137 0,06042377 ! Schwann cell development GO:0014044 14 6 0,000 0,01873137 0,06033914 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01873137 0,06025475 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01873137 0,0601706 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01873137 0,06008668 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01873137 0,06000299 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01873137 0,05991954 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01873137 0,05983632 ! histone ubiquitination GO:0016574 7 6 0,000 0,01873137 0,05975333 ! regulation of meiosis GO:0040020 10 6 0,000 0,01873137 0,05967057 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01873137 0,05958804 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01873137 0,05950573 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01873137 0,05942365 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01873137 0,0593418 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01873137 0,05926018 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01873137 0,05917878 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01873137 0,0590976 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01873137 0,05901664 ! receptor internalization GO:0031623 9 6 0,000 0,01873137 0,05893591 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01873137 0,0588554 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01873137 0,0587751 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01873137 0,05869503 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01873137 0,05861517 ! protein deubiquitination GO:0016579 8 6 0,000 0,01873137 0,05853553 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01873137 0,05845611 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01873137 0,0583769 ! axonal fasciculation GO:0007413 9 6 0,000 0,01873137 0,0582979 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01873137 0,05821912 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01873137 0,05814055 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01873137 0,0580622 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01873137 0,05798405 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01873137 0,05790611 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01873137 0,05782839 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01873137 0,05775087 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01873137 0,05767356 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01873137 0,05759646 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01873137 0,05751956 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01873137 0,05744287 ! adult feeding behavior GO:0008343 6 6 0,000 0,01873137 0,05736638 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01873137 0,05729009 ! pigment granule transport GO:0051904 12 6 0,000 0,01873137 0,05721401 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01873137 0,05713813 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01873137 0,05706245 ! catecholamine transport GO:0051937 7 6 0,000 0,01873137 0,05698697 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01873137 0,05691169 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01873137 0,05683661 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01873137 0,05676173 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01873137 0,05668704 ! protein prenylation GO:0018342 10 6 0,000 0,01873137 0,05661255 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01873137 0,05653825 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01873137 0,05646415 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01873137 0,05639025 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01873137 0,05631654 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01873137 0,05624301 ! acute inflammatory response GO:0002526 92 68 1,000 0,01938911 0,05814206 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,01938911 0,05806635 ! response to drug GO:0042493 108 69 1,000 0,0199281 0,05960291 ! response to metal ion GO:0010038 103 70 1,000 0,02047336 0,06115418 ! eye development GO:0001654 111 70 1,000 0,02047336 0,06107486 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,02102483 0,06263873 ! muscle cell differentiation GO:0042692 104 71 1,000 0,02102483 0,0625577 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,02102483 0,06247687 ! response to hypoxia GO:0001666 132 72 1,000 0,02158247 0,06405121 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,02181959 0,06467147 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02181959 0,06458824 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02181959 0,06450522 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02181959 0,06442241 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02181959 0,06433982 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02181959 0,06425744 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02181959 0,06417527 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02181959 0,06409331 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02181959 0,06401156 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02181959 0,06393001 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02181959 0,06384868 ! reproductive behavior GO:0019098 12 7 0,000 0,02181959 0,06376755 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02181959 0,06368663 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02181959 0,06360591 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02181959 0,06352539 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02181959 0,06344508 ! oligopeptide transport GO:0006857 11 7 0,000 0,02181959 0,06336498 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02181959 0,06328507 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02181959 0,06320537 ! RNA methylation GO:0001510 11 7 0,000 0,02181959 0,06312586 ! pericardium development GO:0060039 8 7 0,000 0,02181959 0,06304656 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02181959 0,06296745 ! fibril organization GO:0043206 13 7 0,000 0,02181959 0,06288855 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02181959 0,06280984 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02181959 0,06273133 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02181959 0,06265301 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02181959 0,06257489 ! lipoprotein transport GO:0042953 9 7 0,000 0,02181959 0,06249696 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02181959 0,06241923 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02181959 0,06234169 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02181959 0,06226434 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02181959 0,06218719 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02181959 0,06211022 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02181959 0,06203345 ! chemosensory behavior GO:0007635 9 7 0,000 0,02181959 0,06195687 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02181959 0,06188047 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02181959 0,06180426 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02181959 0,06172824 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02181959 0,06165241 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02181959 0,06157676 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02181959 0,0615013 ! reflex GO:0060004 12 7 0,000 0,02181959 0,06142602 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02181959 0,06135093 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02181959 0,06127602 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02181959 0,06120129 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02181959 0,06112675 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02181959 0,06105239 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02181959 0,0609782 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02181959 0,0609042 ! adrenal gland development GO:0030325 17 7 0,000 0,02181959 0,06083038 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02181959 0,06075673 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02181959 0,06068327 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02181959 0,06060998 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02181959 0,06053686 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02181959 0,06046393 ! endosome organization GO:0007032 10 7 0,000 0,02181959 0,06039117 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02181959 0,06031858 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02181959 0,06024617 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02181959 0,06017393 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02181959 0,06010187 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02181959 0,06002998 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02181959 0,05995826 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02181959 0,05988671 ! galactose metabolic process GO:0006012 10 7 0,000 0,02181959 0,05981533 ! vesicle fusion GO:0006906 15 7 0,000 0,02181959 0,05974412 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02181959 0,05967308 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02181959 0,05960221 ! organ growth GO:0035265 11 7 0,000 0,02181959 0,05953151 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02181959 0,05946097 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02181959 0,0593906 ! retinol metabolic process GO:0042572 9 7 0,000 0,02181959 0,0593204 ! behavioral fear response GO:0001662 13 7 0,000 0,02181959 0,05925037 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02181959 0,0591805 ! rRNA modification GO:0000154 12 7 0,000 0,02181959 0,05911079 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02181959 0,05904125 ! response to UV-B GO:0010224 11 7 0,000 0,02181959 0,05897187 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02181959 0,05890265 ! intermediate filament organization GO:0045109 11 7 0,000 0,02181959 0,0588336 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02181959 0,05876471 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02181959 0,05869598 ! fibrinolysis GO:0042730 9 7 0,000 0,02181959 0,05862741 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02181959 0,058559 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02181959 0,05849075 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02181959 0,05842266 ! response to tropane GO:0014073 13 7 0,000 0,02181959 0,05835472 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02181959 0,05828695 ! melanosome localization GO:0032400 10 7 0,000 0,02181959 0,05821933 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02181959 0,05815187 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02181959 0,05808456 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02181959 0,05801741 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02181959 0,05795042 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02181959 0,05788358 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02181959 0,05781689 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02181959 0,05775036 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02181959 0,05768398 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02181959 0,05761775 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02181959 0,05755168 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02181959 0,05748575 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02181959 0,05741998 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02181959 0,05735436 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02181959 0,05728888 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02181959 0,05722356 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02181959 0,05715838 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02181959 0,05709336 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02181959 0,05702848 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02181959 0,05696375 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02181959 0,05689916 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02181959 0,05683472 ! diuresis GO:0030146 12 7 0,000 0,02181959 0,05677043 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02181959 0,05670628 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02181959 0,05664228 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02181959 0,05657842 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02181959 0,05651471 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02181959 0,05645114 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02181959 0,05638771 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02181959 0,05632442 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02181959 0,05626128 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02181959 0,05619828 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02181959 0,05613541 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02181959 0,05607269 ! lymph node development GO:0048535 9 7 0,000 0,02181959 0,05601011 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02181959 0,05594767 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02181959 0,05588537 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02181959 0,0558232 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02181959 0,05576118 ! ATP catabolic process GO:0006200 10 7 0,000 0,02181959 0,05569929 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02181959 0,05563754 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02181959 0,05557593 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02181959 0,05551445 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02181959 0,05545311 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02181959 0,0553919 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02181959 0,05533083 ! muscle adaptation GO:0043500 12 7 0,000 0,02181959 0,05526989 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02181959 0,05520909 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02181959 0,05514842 ! retina homeostasis GO:0001895 9 7 0,000 0,02181959 0,05508788 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02181959 0,05502748 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02181959 0,05496721 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02181959 0,05490707 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02181959 0,05484706 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02181959 0,05478718 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02181959 0,05472744 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02181959 0,05466782 ! negative regulation of transport GO:0051051 116 73 1,000 0,02214625 0,05542587 ! regulation of blood pressure GO:0008217 107 73 1,000 0,02214625 0,05536563 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,02214625 0,05530551 ! response to oxygen levels GO:0070482 137 74 1,000 0,02271612 0,05666711 ! response to inorganic substance GO:0010035 115 75 1,000 0,02329204 0,05804083 ! response to nutrient GO:0007584 104 75 1,000 0,02329204 0,05797801 ! sex differentiation GO:0007548 105 77 1,000 0,02446184 0,06082404 ! protein ubiquitination GO:0016567 125 77 1,000 0,02446184 0,06075836 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02489827 0,06177565 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02489827 0,06170908 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02489827 0,06164265 ! axon extension GO:0048675 11 8 0,000 0,02489827 0,06157637 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02489827 0,06151023 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02489827 0,06144423 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02489827 0,06137837 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02489827 0,06131266 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02489827 0,06124708 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02489827 0,06118165 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02489827 0,06111635 ! phosphate transport GO:0006817 10 8 0,000 0,02489827 0,0610512 ! N-glycan processing GO:0006491 12 8 0,000 0,02489827 0,06098618 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02489827 0,0609213 ! UTP metabolic process GO:0046051 8 8 0,000 0,02489827 0,06085656 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02489827 0,06079196 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02489827 0,06072749 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02489827 0,06066316 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02489827 0,06059897 ! succinate metabolic process GO:0006105 14 8 0,000 0,02489827 0,06053491 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02489827 0,06047099 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02489827 0,0604072 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02489827 0,06034354 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02489827 0,06028002 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02489827 0,06021664 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02489827 0,06015339 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02489827 0,06009027 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02489827 0,06002728 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02489827 0,05996442 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02489827 0,0599017 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02489827 0,05983911 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02489827 0,05977664 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02489827 0,05971431 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02489827 0,05965211 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02489827 0,05959003 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02489827 0,05952809 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02489827 0,05946628 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02489827 0,05940459 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02489827 0,05934303 ! melanin metabolic process GO:0006582 12 8 0,000 0,02489827 0,0592816 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02489827 0,05922029 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02489827 0,05915912 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02489827 0,05909806 ! macrophage activation GO:0042116 12 8 0,000 0,02489827 0,05903714 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02489827 0,05897634 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02489827 0,05891566 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02489827 0,05885511 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02489827 0,05879469 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02489827 0,05873438 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02489827 0,0586742 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02489827 0,05861415 ! osteoblast development GO:0002076 13 8 0,000 0,02489827 0,05855422 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02489827 0,05849441 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02489827 0,05843472 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02489827 0,05837515 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02489827 0,05831571 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02489827 0,05825638 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02489827 0,05819718 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02489827 0,0581381 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02489827 0,05807913 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02489827 0,05802029 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02489827 0,05796156 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02489827 0,05790296 ! segment specification GO:0007379 10 8 0,000 0,02489827 0,05784447 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02489827 0,0577861 ! cellular extravasation GO:0045123 11 8 0,000 0,02489827 0,05772785 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02489827 0,05766971 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02489827 0,05761169 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02489827 0,05755379 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02489827 0,05749601 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02489827 0,05743834 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02489827 0,05738079 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02489827 0,05732335 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02489827 0,05726602 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02489827 0,05720881 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02489827 0,05715172 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02489827 0,05709474 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02489827 0,05703787 ! icosanoid secretion GO:0032309 12 8 0,000 0,02489827 0,05698112 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02489827 0,05692448 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02489827 0,05686795 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02489827 0,05681153 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02489827 0,05675523 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02489827 0,05669903 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02489827 0,05664295 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02489827 0,05658698 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02489827 0,05653112 ! sterol catabolic process GO:0016127 9 8 0,000 0,02489827 0,05647537 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02489827 0,05641973 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02489827 0,0563642 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02489827 0,05630877 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02489827 0,05625346 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02489827 0,05619826 ! prophase GO:0051324 11 8 0,000 0,02489827 0,05614316 ! S phase GO:0051320 8 8 0,000 0,02489827 0,05608817 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02489827 0,05603329 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02489827 0,05597852 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02489827 0,05592385 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02489827 0,05586929 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02489827 0,05581484 ! hormone catabolic process GO:0042447 13 8 0,000 0,02489827 0,05576049 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02489827 0,05570625 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02489827 0,05565211 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02489827 0,05559808 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02489827 0,05554415 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02489827 0,05549033 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02489827 0,05543662 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02489827 0,055383 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02489827 0,05532949 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02489827 0,05527608 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02489827 0,05522278 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02489827 0,05516958 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02489827 0,05511648 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02489827 0,05506348 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02489827 0,05501059 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02489827 0,0549578 ! T cell activation GO:0042110 134 79 1,000 0,02565534 0,05657457 ! forebrain development GO:0030900 131 80 1,000 0,02626086 0,05785439 ! mRNA transport GO:0051028 121 81 1,000 0,02687219 0,05914452 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,02687219 0,05908798 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02796744 0,06143754 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02796744 0,06137892 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02796744 0,0613204 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02796744 0,061262 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02796744 0,06120371 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02796744 0,06114554 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02796744 0,06108747 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02796744 0,06102951 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02796744 0,06097166 ! GTP metabolic process GO:0046039 9 9 0,000 0,02796744 0,06091392 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02796744 0,0608563 ! social behavior GO:0035176 14 9 0,000 0,02796744 0,06079877 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02796744 0,06074136 ! artery development GO:0060840 19 9 0,000 0,02796744 0,06068406 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02796744 0,06062687 ! response to pain GO:0048265 16 9 0,000 0,02796744 0,06056978 ! protein complex disassembly GO:0043241 17 9 0,000 0,02796744 0,0605128 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02796744 0,06045592 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02796744 0,06039916 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02796744 0,0603425 ! lung alveolus development GO:0048286 17 9 0,000 0,02796744 0,06028595 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02796744 0,0602295 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02796744 0,06017316 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02796744 0,06011692 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02796744 0,06006079 ! protein targeting to ER GO:0045047 19 9 0,000 0,02796744 0,06000476 ! T cell selection GO:0045058 18 9 0,000 0,02796744 0,05994884 ! endoderm development GO:0007492 12 9 0,000 0,02796744 0,05989302 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02796744 0,05983731 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02796744 0,0597817 ! arginine catabolic process GO:0006527 10 9 0,000 0,02796744 0,05972619 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02796744 0,05967078 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02796744 0,05961548 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02796744 0,05956028 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02796744 0,05950518 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02796744 0,05945019 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02796744 0,05939529 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02796744 0,0593405 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02796744 0,05928581 ! mannose metabolic process GO:0006013 9 9 0,000 0,02796744 0,05923122 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02796744 0,05917673 ! receptor clustering GO:0043113 15 9 0,000 0,02796744 0,05912234 ! epithelial cell development GO:0002064 10 9 0,000 0,02796744 0,05906805 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02796744 0,05901386 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02796744 0,05895977 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02796744 0,05890577 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02796744 0,05885188 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02796744 0,05879808 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02796744 0,05874439 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02796744 0,05869079 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02796744 0,05863729 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02796744 0,05858388 ! DNA ligation GO:0006266 14 9 0,000 0,02796744 0,05853058 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02796744 0,05847737 ! response to amine stimulus GO:0014075 13 9 0,000 0,02796744 0,05842425 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02796744 0,05837124 ! erythrocyte development GO:0048821 11 9 0,000 0,02796744 0,05831832 ! renal water homeostasis GO:0003091 14 9 0,000 0,02796744 0,05826549 ! postreplication repair GO:0006301 11 9 0,000 0,02796744 0,05821276 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02796744 0,05816013 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02796744 0,05810759 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02796744 0,05805515 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02796744 0,0580028 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02796744 0,05795054 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02796744 0,05789838 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02796744 0,05784632 ! acid secretion GO:0046717 14 9 0,000 0,02796744 0,05779434 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02796744 0,05774246 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02796744 0,05769068 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02796744 0,05763898 ! purine base metabolic process GO:0006144 18 9 0,000 0,02796744 0,05758738 ! thymus development GO:0048538 15 9 0,000 0,02796744 0,05753587 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02796744 0,05748445 ! spleen development GO:0048536 15 9 0,000 0,02796744 0,05743313 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02796744 0,05738189 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02796744 0,05733075 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02796744 0,0572797 ! detection of calcium ion GO:0005513 13 9 0,000 0,02796744 0,05722874 ! blastocyst formation GO:0001825 12 9 0,000 0,02796744 0,05717787 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02796744 0,05712709 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02796744 0,0570764 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02796744 0,0570258 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02796744 0,05697529 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02796744 0,05692487 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02796744 0,05687454 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02796744 0,0568243 ! prepulse inhibition GO:0060134 14 9 0,000 0,02796744 0,05677414 ! embryonic placenta development GO:0001892 12 9 0,000 0,02796744 0,05672408 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02796744 0,0566741 ! insulin secretion GO:0030073 17 9 0,000 0,02796744 0,05662421 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02796744 0,05657441 ! response to nicotine GO:0035094 16 9 0,000 0,02796744 0,0565247 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02796744 0,05647507 ! nucleus localization GO:0051647 15 9 0,000 0,02796744 0,05642553 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02796744 0,05637608 ! localization within membrane GO:0051668 15 9 0,000 0,02796744 0,05632671 ! regulation of defense response GO:0031347 117 84 1,000 0,02874053 0,05783308 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,02874053 0,05778253 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,03065958 0,06158693 GO:0060538|skeletal muscle organ development, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03102712 0,06227083 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03102712 0,06221654 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03102712 0,06216234 ! thyroid gland development GO:0030878 19 10 0,000 0,03102712 0,06210824 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03102712 0,06205423 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03102712 0,06200032 ! synapsis GO:0007129 13 10 0,000 0,03102712 0,0619465 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03102712 0,06189277 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03102712 0,06183914 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03102712 0,0617856 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03102712 0,06173215 ! sulfate transport GO:0008272 12 10 0,000 0,03102712 0,0616788 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03102712 0,06162553 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03102712 0,06157236 ! androgen metabolic process GO:0008209 13 10 0,000 0,03102712 0,06151928 ! phospholipid efflux GO:0033700 16 10 0,000 0,03102712 0,06146629 ! hippocampus development GO:0021766 19 10 0,000 0,03102712 0,0614134 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03102712 0,06136059 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03102712 0,06130788 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03102712 0,06125525 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03102712 0,06120272 ! pathogenesis GO:0009405 13 10 0,000 0,03102712 0,06115027 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03102712 0,06109792 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03102712 0,06104565 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03102712 0,06099348 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03102712 0,06094139 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03102712 0,06088939 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03102712 0,06083748 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03102712 0,06078566 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03102712 0,06073393 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03102712 0,06068229 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03102712 0,06063073 ! B cell proliferation GO:0042100 14 10 0,000 0,03102712 0,06057926 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03102712 0,06052788 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03102712 0,06047658 ! forebrain cell migration GO:0021885 17 10 0,000 0,03102712 0,06042538 ! lipid digestion GO:0044241 15 10 0,000 0,03102712 0,06037425 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03102712 0,06032322 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03102712 0,06027227 ! UV protection GO:0009650 14 10 0,000 0,03102712 0,06022141 ! entry into host cell GO:0030260 20 10 0,000 0,03102712 0,06017063 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03102712 0,06011994 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03102712 0,06006933 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03102712 0,06001881 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03102712 0,05996838 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03102712 0,05991803 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03102712 0,05986776 ! regulation of organ growth GO:0046620 11 10 0,000 0,03102712 0,05981758 ! response to dsRNA GO:0043331 18 10 0,000 0,03102712 0,05976748 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03102712 0,05971746 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03102712 0,05966753 ! embryonic axis specification GO:0000578 12 10 0,000 0,03102712 0,05961768 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03102712 0,05956792 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03102712 0,05951824 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03102712 0,05946864 ! fucose catabolic process GO:0019317 16 10 0,000 0,03102712 0,05941912 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03102712 0,05936969 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03102712 0,05932034 ! protein sumoylation GO:0016925 12 10 0,000 0,03102712 0,05927107 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03102712 0,05922188 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03102712 0,05917278 ! zymogen activation GO:0031638 14 10 0,000 0,03102712 0,05912375 ! salivary gland development GO:0007431 22 10 0,000 0,03102712 0,05907481 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03102712 0,05902595 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03102712 0,05897716 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03102712 0,05892846 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03102712 0,05887984 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03102712 0,0588313 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03102712 0,05878284 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03102712 0,05873446 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03102712 0,05868616 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03102712 0,05863794 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03102712 0,05858979 ! detection of bacterium GO:0016045 10 10 0,000 0,03102712 0,05854173 ! activation of innate immune response GO:0002218 10 10 0,000 0,03102712 0,05849374 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03102712 0,05844584 ! developmental induction GO:0031128 13 10 0,000 0,03102712 0,05839801 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03102712 0,05835026 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03102712 0,05830259 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03102712 0,05825499 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03102712 0,05820748 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,03131035 0,05869095 ! establishment of RNA localization GO:0051236 128 88 1,000 0,03131035 0,05864316 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of neurogenesis GO:0050767 153 89 1,000 0,03196659 0,05982356 ! regulation of T cell activation GO:0050863 128 89 1,000 0,03196659 0,05977492 ! leukocyte differentiation GO:0002521 143 90 1,000 0,03262826 0,06096263 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,03262826 0,06091315 ! RNA localization GO:0006403 135 91 1,000 0,03329533 0,06210808 ! response to virus GO:0009615 122 91 1,000 0,03329533 0,06205775 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,03396776 0,0632598 ! DNA recombination GO:0006310 146 92 1,000 0,03396776 0,06320861 ! rRNA transcription GO:0009303 17 11 0,000 0,03407734 0,06336126 ! respiratory burst GO:0045730 14 11 0,000 0,03407734 0,06331008 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03407734 0,06325899 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03407734 0,06320797 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,03407734 0,06315704 ! filopodium assembly GO:0046847 19 11 0,000 0,03407734 0,06310619 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03407734 0,06305542 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03407734 0,06300473 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03407734 0,06295412 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03407734 0,0629036 ! mating GO:0007618 14 11 0,000 0,03407734 0,06285315 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03407734 0,06280279 ! T cell proliferation GO:0042098 20 11 0,000 0,03407734 0,06275251 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03407734 0,06270231 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03407734 0,06265218 ! bone resorption GO:0045453 16 11 0,000 0,03407734 0,06260214 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03407734 0,06255218 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03407734 0,0625023 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03407734 0,0624525 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03407734 0,06240277 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03407734 0,06235313 ! syncytium formation GO:0006949 15 11 0,000 0,03407734 0,06230356 ! plasma membrane organization GO:0007009 18 11 0,000 0,03407734 0,06225408 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03407734 0,06220467 ! focal adhesion formation GO:0048041 24 11 0,000 0,03407734 0,06215534 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03407734 0,06210609 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03407734 0,06205691 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03407734 0,06200782 ! adult heart development GO:0007512 11 11 0,000 0,03407734 0,0619588 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03407734 0,06190986 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03407734 0,061861 ! temperature homeostasis GO:0001659 16 11 0,000 0,03407734 0,06181221 ! L-glutamate transport GO:0015813 16 11 0,000 0,03407734 0,0617635 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03407734 0,06171487 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03407734 0,06166631 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03407734 0,06161783 ! stem cell development GO:0048864 29 11 0,000 0,03407734 0,06156943 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03407734 0,0615211 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03407734 0,06147285 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03407734 0,06142467 ! vasoconstriction GO:0042310 15 11 0,000 0,03407734 0,06137657 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03407734 0,06132855 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03407734 0,0612806 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03407734 0,06123272 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03407734 0,06118492 ! ribosome assembly GO:0042255 13 11 0,000 0,03407734 0,06113719 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03407734 0,06108954 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03407734 0,06104196 ! chromatin silencing GO:0006342 19 11 0,000 0,03407734 0,06099446 ! nucleosome positioning GO:0016584 13 11 0,000 0,03407734 0,06094703 ! T cell homeostasis GO:0043029 20 11 0,000 0,03407734 0,06089968 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03407734 0,06085239 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03407734 0,06080518 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03407734 0,06075805 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03407734 0,06071099 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03407734 0,060664 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03407734 0,06061708 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03407734 0,06057023 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03407734 0,06052346 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03407734 0,06047676 ! male genitalia development GO:0030539 13 11 0,000 0,03407734 0,06043013 ! cholesterol efflux GO:0033344 19 11 0,000 0,03407734 0,06038358 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03407734 0,06033709 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03407734 0,06029068 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03407734 0,06024434 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03407734 0,06019807 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03407734 0,06015187 ! defense response to fungus GO:0050832 12 11 0,000 0,03407734 0,06010574 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03407734 0,06005968 ! lysogeny GO:0030069 18 11 0,000 0,03407734 0,06001369 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03407734 0,05996778 ! acrosome reaction GO:0007340 13 11 0,000 0,03407734 0,05992193 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03407734 0,05987615 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,0346455 0,06082798 ! response to oxidative stress GO:0006979 141 94 1,000 0,03532853 0,06197987 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,03671025 0,06435487 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,03671025 0,06430585 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,03671025 0,06425691 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,03671025 0,06420805 ! lactation GO:0007595 20 12 0,000 0,03711814 0,06487212 ! reproductive cellular process GO:0048610 14 12 0,000 0,03711814 0,06482287 ! tRNA modification GO:0006400 14 12 0,000 0,03711814 0,06477368 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03711814 0,06472457 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03711814 0,06467554 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03711814 0,06462658 ! non-recombinational repair GO:0000726 19 12 0,000 0,03711814 0,0645777 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03711814 0,06452888 ! peroxisomal transport GO:0043574 21 12 0,000 0,03711814 0,06448015 ! cartilage condensation GO:0001502 18 12 0,000 0,03711814 0,06443148 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03711814 0,06438289 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03711814 0,06433437 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03711814 0,06428593 ! heart looping GO:0001947 15 12 0,000 0,03711814 0,06423756 ! palate development GO:0060021 15 12 0,000 0,03711814 0,06418926 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03711814 0,06414103 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03711814 0,06409288 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03711814 0,0640448 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03711814 0,06399679 ! arginine metabolic process GO:0006525 13 12 0,000 0,03711814 0,06394885 ! methionine metabolic process GO:0006555 13 12 0,000 0,03711814 0,06390098 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03711814 0,06385319 ! Golgi organization GO:0007030 18 12 0,000 0,03711814 0,06380547 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03711814 0,06375781 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03711814 0,06371023 ! monoamine transport GO:0015844 13 12 0,000 0,03711814 0,06366272 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03711814 0,06361529 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03711814 0,06356792 ! L-amino acid transport GO:0015807 20 12 0,000 0,03711814 0,06352062 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03711814 0,06347339 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03711814 0,06342624 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03711814 0,06337915 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03711814 0,06333213 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03711814 0,06328518 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03711814 0,06323831 ! cerebellum development GO:0021549 13 12 0,000 0,03711814 0,0631915 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03711814 0,06314476 ! histone acetylation GO:0016573 23 12 0,000 0,03711814 0,06309809 ! histone methylation GO:0016571 15 12 0,000 0,03711814 0,06305149 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03711814 0,06300495 ! gland morphogenesis GO:0022612 23 12 0,000 0,03711814 0,06295849 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03711814 0,0629121 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03711814 0,06286577 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03711814 0,06281951 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03711814 0,06277332 ! intestinal absorption GO:0050892 19 12 0,000 0,03711814 0,0627272 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03711814 0,06268114 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03711814 0,06263515 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03711814 0,06258923 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03711814 0,06254338 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03711814 0,06249759 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03711814 0,06245188 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03711814 0,06240622 ! microspike assembly GO:0030035 23 12 0,000 0,03711814 0,06236064 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03711814 0,06231512 ! response to cold GO:0009409 14 12 0,000 0,03711814 0,06226967 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,03740888 0,06271168 ! extracellular structure organization GO:0043062 156 99 1,000 0,03882148 0,06503233 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,03953537 0,06618002 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,03953537 0,06613189 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04014953 0,06711041 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04014953 0,06706167 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04014953 0,06701301 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04014953 0,06696441 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04014953 0,06691589 ! water transport GO:0006833 17 13 0,000 0,04014953 0,06686743 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04014953 0,06681905 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04014953 0,06677073 ! lipid localization GO:0010876 24 13 0,000 0,04014953 0,06672249 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04014953 0,06667431 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04014953 0,06662621 ! organelle fusion GO:0048284 28 13 0,000 0,04014953 0,06657817 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04014953 0,06653021 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04014953 0,06648231 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04014953 0,06643448 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04014953 0,06638672 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04014953 0,06633903 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04014953 0,0662914 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04014953 0,06624385 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04014953 0,06619636 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04014953 0,06614894 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04014953 0,06610159 ! NAD metabolic process GO:0019674 21 13 0,000 0,04014953 0,06605431 ! exocrine system development GO:0035272 27 13 0,000 0,04014953 0,0660071 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04014953 0,06595995 ! bone mineralization GO:0030282 15 13 0,000 0,04014953 0,06591287 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04014953 0,06586585 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04014953 0,06581891 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04014953 0,06577203 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04014953 0,06572521 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04014953 0,06567847 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04014953 0,06563179 ! genitalia development GO:0048806 15 13 0,000 0,04014953 0,06558517 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,04014953 0,06553863 ! cellular pigmentation GO:0033059 24 13 0,000 0,04014953 0,06549215 ! tissue regeneration GO:0042246 21 13 0,000 0,04014953 0,06544573 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04014953 0,06539938 ! cofactor transport GO:0051181 19 13 0,000 0,04014953 0,0653531 ! NADP metabolic process GO:0006739 18 13 0,000 0,04014953 0,06530688 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04014953 0,06526073 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04014953 0,06521464 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04014953 0,06516861 ! gas transport GO:0015669 18 13 0,000 0,04014953 0,06512266 ! regulation of RNA stability GO:0043487 28 13 0,000 0,04014953 0,06507676 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04014953 0,06503093 ! regulation of axon extension GO:0030516 23 13 0,000 0,04014953 0,06498517 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04014953 0,06493947 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04014953 0,06489383 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04014953 0,06484826 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04014953 0,06480276 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04014953 0,06475731 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04014953 0,06471193 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04317156 0,06953402 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04317156 0,06948536 ! superoxide anion generation GO:0042554 18 14 0,000 0,04317156 0,06943677 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04317156 0,06938825 ! myotube differentiation GO:0014902 21 14 0,000 0,04317156 0,06933979 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04317156 0,06929141 ! inositol metabolic process GO:0006020 20 14 0,000 0,04317156 0,06924309 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04317156 0,06919483 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04317156 0,06914665 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04317156 0,06909853 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04317156 0,06905048 ! response to cAMP GO:0051591 19 14 0,000 0,04317156 0,06900249 ! limbic system development GO:0021761 25 14 0,000 0,04317156 0,06895457 ! startle response GO:0001964 21 14 0,000 0,04317156 0,06890672 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04317156 0,06885894 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04317156 0,06881122 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04317156 0,06876356 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04317156 0,06871598 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04317156 0,06866846 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04317156 0,068621 ! glycine metabolic process GO:0006544 22 14 0,000 0,04317156 0,06857361 ! pituitary gland development GO:0021983 23 14 0,000 0,04317156 0,06852628 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04317156 0,06847903 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04317156 0,06843183 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04317156 0,0683847 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04317156 0,06833764 ! embryo implantation GO:0007566 27 14 0,000 0,04317156 0,06829064 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04317156 0,0682437 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04317156 0,06819683 ! axon cargo transport GO:0008088 27 14 0,000 0,04317156 0,06815002 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04317156 0,06810328 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04317156 0,0680566 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04317156 0,06800999 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04317156 0,06796344 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04317156 0,06791695 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04317156 0,06787053 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04317156 0,06782417 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04317156 0,06777787 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04317156 0,06773164 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04317156 0,06768547 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04317156 0,06763936 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04317156 0,06759332 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04317156 0,06754734 ! muscle maintenance GO:0046716 19 14 0,000 0,04317156 0,06750142 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04317156 0,06745556 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04317156 0,06740977 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04317156 0,06736403 ! cell killing GO:0001906 20 14 0,000 0,04317156 0,06731836 ! cilium assembly GO:0042384 20 14 0,000 0,04317156 0,06727275 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04317156 0,06722721 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04618424 0,07186993 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04618424 0,07182134 ! metencephalon development GO:0022037 19 15 0,000 0,04618424 0,07177281 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04618424 0,07172435 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04618424 0,07167595 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04618424 0,07162762 ! skin development GO:0043588 25 15 0,000 0,04618424 0,07157935 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04618424 0,07153115 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04618424 0,07148301 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04618424 0,07143494 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,04618424 0,07138694 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04618424 0,07133899 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04618424 0,07129111 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04618424 0,0712433 ! adult walking behavior GO:0007628 25 15 0,000 0,04618424 0,07119555 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04618424 0,07114786 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04618424 0,07110024 ! myoblast differentiation GO:0045445 27 15 0,000 0,04618424 0,07105268 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04618424 0,07100519 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,04618424 0,07095776 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04618424 0,07091039 ! cerebral cortex development GO:0021987 29 15 0,000 0,04618424 0,07086308 ! response to osmotic stress GO:0006970 22 15 0,000 0,04618424 0,07081584 ! vesicle coating GO:0006901 25 15 0,000 0,04618424 0,07076866 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04618424 0,07072154 ! DNA integration GO:0015074 22 15 0,000 0,04618424 0,07067449 ! peptide secretion GO:0002790 27 15 0,000 0,04618424 0,0706275 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04618424 0,07058057 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04618424 0,0705337 ! neuron recognition GO:0008038 22 15 0,000 0,04618424 0,0704869 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04618424 0,07044016 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04618424 0,07039348 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04618424 0,07034686 ! biomineral formation GO:0031214 18 15 0,000 0,04618424 0,0703003 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04618424 0,07025381 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04618424 0,07020738 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04618424 0,070161 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04618424 0,07011469 ! organic cation transport GO:0015695 19 15 0,000 0,04618424 0,07006844 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04618424 0,07002225 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,04618424 0,06997613 ! peptide hormone processing GO:0016486 19 15 0,000 0,04618424 0,06993006 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,04618424 0,06988405 ! protein secretion GO:0009306 27 16 0,000 0,04918761 0,07437969 ! hormone secretion GO:0046879 25 16 0,000 0,04918761 0,07433082 ! bone remodeling GO:0046849 24 16 0,000 0,04918761 0,07428202 ! endothelial cell migration GO:0043542 22 16 0,000 0,04918761 0,07423327 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04918761 0,0741846 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,04918761 0,07413598 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04918761 0,07408743 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04918761 0,07403895 ! glial cell development GO:0021782 24 16 0,000 0,04918761 0,07399052 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04918761 0,07394216 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04918761 0,07389387 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04918761 0,07384563 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04918761 0,07379746 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04918761 0,07374936 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04918761 0,07370131 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04918761 0,07365333 ! fructose metabolic process GO:0006000 20 16 0,000 0,04918761 0,07360541 ! regulation of protein binding GO:0043393 27 16 0,000 0,04918761 0,07355755 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04918761 0,07350975 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04918761 0,07346202 ! protein export from nucleus GO:0006611 24 16 0,000 0,04918761 0,07341435 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04918761 0,07336674 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04918761 0,07331919 ! DNA replication initiation GO:0006270 25 16 0,000 0,04918761 0,0732717 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04918761 0,07322428 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04918761 0,07317692 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04918761 0,07312961 ! diencephalon development GO:0021536 25 16 0,000 0,04918761 0,07308237 ! neural crest cell migration GO:0001755 24 16 0,000 0,04918761 0,07303519 ! G1 phase GO:0051318 27 16 0,000 0,04918761 0,07298807 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04918761 0,07294101 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04918761 0,07289401 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04918761 0,07284708 ! steroid catabolic process GO:0006706 22 16 0,000 0,04918761 0,0728002 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04918761 0,07275338 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04918761 0,07270663 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04918761 0,07265993 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04918761 0,07261329 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04918761 0,07256672 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04918761 0,0725202 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04918761 0,07247374 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04918761 0,07242734 ! negative regulation of translation GO:0017148 22 16 0,000 0,04918761 0,07238101 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0521817 0,07673779 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0521817 0,07668876 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0521817 0,07663979 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0521817 0,07659088 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,0521817 0,07654203 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0521817 0,07649325 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0521817 0,07644453 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0521817 0,07639587 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0521817 0,07634727 ! signal complex assembly GO:0007172 29 17 0,000 0,0521817 0,07629873 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0521817 0,07625026 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0521817 0,07620184 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0521817 0,07615349 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,0521817 0,0761052 ! memory GO:0007613 25 17 0,000 0,0521817 0,07605697 ! keratinization GO:0031424 17 17 0,000 0,0521817 0,07600881 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0521817 0,0759607 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,0521817 0,07591265 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0521817 0,07586467 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0521817 0,07581674 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,0521817 0,07576888 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0521817 0,07572108 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,0521817 0,07567333 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,0521817 0,07562565 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0521817 0,07557803 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0521817 0,07553046 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0521817 0,07548296 ! membrane budding GO:0006900 29 17 0,000 0,0521817 0,07543552 ! heme metabolic process GO:0042168 27 17 0,000 0,0521817 0,07538813 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0521817 0,07534081 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,0521817 0,07529354 ! body fluid secretion GO:0007589 27 17 0,000 0,0521817 0,07524634 ! stem cell differentiation GO:0048863 36 17 0,000 0,0521817 0,07519919 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0521817 0,0751521 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0521817 0,07510507 ! sensory perception of pain GO:0019233 23 17 0,000 0,0521817 0,0750581 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0521817 0,07501119 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0521817 0,07496434 ! synaptogenesis GO:0007416 24 17 0,000 0,0521817 0,07491754 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0521817 0,07487081 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0521817 0,07482413 ! cell-cell junction organization GO:0045216 25 17 0,000 0,0521817 0,07477751 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0521817 0,07473095 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0521817 0,07468445 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,0521817 0,074638 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,0521817 0,07459161 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0521817 0,07454528 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,05516653 0,0787604 ! positive regulation of translation GO:0045727 28 18 0,000 0,05516653 0,07871154 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,05516653 0,07866275 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05516653 0,07861401 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05516653 0,07856533 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05516653 0,07851671 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05516653 0,07846816 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05516653 0,07841966 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05516653 0,07837122 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05516653 0,07832284 ! axis specification GO:0009798 26 18 0,000 0,05516653 0,07827453 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05516653 0,07822627 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05516653 0,07817807 ! pancreas development GO:0031016 26 18 0,000 0,05516653 0,07812993 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05516653 0,07808185 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05516653 0,07803383 ! response to retinoic acid GO:0032526 25 18 0,000 0,05516653 0,07798587 ! pigmentation during development GO:0048066 31 18 0,000 0,05516653 0,07793797 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05516653 0,07789012 ! fucose metabolic process GO:0006004 26 18 0,000 0,05516653 0,07784234 ! response to fungus GO:0009620 19 18 0,000 0,05516653 0,07779461 ! peptide cross-linking GO:0018149 31 18 0,000 0,05516653 0,07774694 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05516653 0,07769933 ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05516653 0,07765178 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05516653 0,07760429 ! visual learning GO:0008542 35 18 0,000 0,05516653 0,07755685 ! somitogenesis GO:0001756 24 18 0,000 0,05516653 0,07750947 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05516653 0,07746215 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,05516653 0,07741489 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05516653 0,07736769 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05516653 0,07732054 ! vitamin transport GO:0051180 24 18 0,000 0,05516653 0,07727345 ! hormone transport GO:0009914 27 18 0,000 0,05516653 0,07722642 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05516653 0,07717945 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05516653 0,07713253 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05516653 0,07708567 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05516653 0,07703886 ! cell-cell recognition GO:0009988 20 18 0,000 0,05516653 0,07699212 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05516653 0,07694543 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05516653 0,07689879 ! regulation of glucose import GO:0046324 21 18 0,000 0,05516653 0,07685222 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05516653 0,07680569 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,05814212 0,08089951 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,05814212 0,08085059 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05814212 0,08080174 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05814212 0,08075295 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05814212 0,08070421 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05814212 0,08065554 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05814212 0,08060692 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,05814212 0,08055836 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05814212 0,08050986 ! regeneration GO:0031099 32 19 0,000 0,05814212 0,08046142 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05814212 0,08041304 ! response to alkaloid GO:0043279 32 19 0,000 0,05814212 0,08036471 ! sensory perception of taste GO:0050909 23 19 0,000 0,05814212 0,08031645 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05814212 0,08026824 ! peroxisome organization GO:0007031 29 19 0,000 0,05814212 0,08022009 ! digestive system process GO:0022600 30 19 0,000 0,05814212 0,08017199 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05814212 0,08012396 ! response to vitamin A GO:0033189 26 19 0,000 0,05814212 0,08007598 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05814212 0,08002806 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05814212 0,07998019 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05814212 0,07993239 ! plasma membrane fusion GO:0045026 23 19 0,000 0,05814212 0,07988464 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,05814212 0,07983695 ! cytolysis GO:0019835 20 19 0,000 0,05814212 0,07978931 ! renal system process GO:0003014 35 19 0,000 0,05814212 0,07974173 ! vasodilation GO:0042311 33 19 0,000 0,05814212 0,07969421 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05814212 0,07964674 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05814212 0,07959934 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05814212 0,07955198 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05814212 0,07950469 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05814212 0,07945745 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05814212 0,07941026 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05814212 0,07936314 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,05814212 0,07931606 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05814212 0,07926905 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05814212 0,07922209 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05814212 0,07917518 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05814212 0,07912833 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,05814212 0,07908154 ! protein stabilization GO:0050821 26 19 0,000 0,05814212 0,0790348 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,06110852 0,08301807 ! iron ion transport GO:0006826 37 20 0,000 0,06110852 0,08296906 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,06110852 0,08292012 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,06110852 0,08287122 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,06110852 0,08282239 ! response to vitamin GO:0033273 29 20 0,000 0,06110852 0,08277361 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,06110852 0,08272489 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,06110852 0,08267623 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,06110852 0,08262763 ! response to ethanol GO:0045471 37 20 0,000 0,06110852 0,08257908 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,06110852 0,08253059 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,06110852 0,08248216 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,06110852 0,08243378 ! chromosome condensation GO:0030261 31 20 0,000 0,06110852 0,08238546 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,06110852 0,0823372 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,06110852 0,08228899 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,06110852 0,08224084 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,06110852 0,08219275 ! pallium development GO:0021543 38 20 0,000 0,06110852 0,08214471 ! DNA modification GO:0006304 28 20 0,000 0,06110852 0,08209673 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,06110852 0,0820488 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,06110852 0,08200093 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,06110852 0,08195312 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,06110852 0,08190536 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,06110852 0,08185766 ! collagen catabolic process GO:0030574 25 20 0,000 0,06110852 0,08181001 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,06110852 0,08176242 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,06110852 0,08171488 ! alditol metabolic process GO:0019400 24 20 0,000 0,06110852 0,0816674 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,06406574 0,08556981 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,06406574 0,08552014 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,06406574 0,08547054 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,06406574 0,08542099 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,06406574 0,0853715 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,06406574 0,08532207 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,06406574 0,08527269 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,06406574 0,08522337 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,06406574 0,08517411 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,06406574 0,0851249 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,06406574 0,08507576 ! protein amino acid acylation GO:0043543 37 21 0,000 0,06406574 0,08502666 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,06406574 0,08497763 ! vesicle docking GO:0048278 27 21 0,000 0,06406574 0,08492865 ! phototransduction GO:0007602 25 21 0,000 0,06406574 0,08487973 ! dendrite development GO:0016358 35 21 0,000 0,06406574 0,08483086 ! visual behavior GO:0007632 39 21 0,000 0,06406574 0,08478205 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,06406574 0,0847333 ! ovarian follicle development GO:0001541 30 21 0,000 0,06406574 0,0846846 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,06406574 0,08463596 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,06406574 0,08458738 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,06406574 0,08453885 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,06406574 0,08449037 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,06406574 0,08444195 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,06406574 0,08439359 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,06406574 0,08434528 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,06406574 0,08429703 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,06406574 0,08424883 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,06406574 0,08420069 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,06406574 0,0841526 ! fatty acid transport GO:0015908 30 21 0,000 0,06406574 0,08410457 ! immunoglobulin production GO:0002377 33 21 0,000 0,06406574 0,08405659 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,06406574 0,08400867 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,06406574 0,0839608 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,06406574 0,08391299 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,06406574 0,08386523 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,06406574 0,08381752 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,06406574 0,08376987 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,06406574 0,08372228 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,06406574 0,08367474 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,06406574 0,08362725 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,06406574 0,08357981 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,06406574 0,08353243 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,06406574 0,0834851 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,06406574 0,08343783 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06701382 0,08722795 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,06701382 0,08717861 ! viral genome replication GO:0019079 29 22 0,000 0,06701382 0,08712933 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06701382 0,08708011 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06701382 0,08703094 ! molting cycle process GO:0022404 40 22 0,000 0,06701382 0,08698182 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06701382 0,08693276 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,06701382 0,08688376 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06701382 0,08683481 ! vasculogenesis GO:0001570 33 22 0,000 0,06701382 0,08678592 ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,06701382 0,08673708 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06701382 0,08668829 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06701382 0,08663957 ! lysosome organization GO:0007040 37 22 0,000 0,06701382 0,08659089 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06701382 0,08654227 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06701382 0,08649371 ! regulation of behavior GO:0050795 38 22 0,000 0,06701382 0,0864452 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06701382 0,08639674 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06701382 0,08634834 ! membrane depolarization GO:0051899 35 22 0,000 0,06701382 0,08629999 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06701382 0,0862517 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06701382 0,08620346 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06701382 0,08615528 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06701382 0,08610714 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06701382 0,08605907 ! neural tube closure GO:0001843 33 22 0,000 0,06701382 0,08601104 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06701382 0,08596307 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06995278 0,08968305 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06995278 0,08963309 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06995278 0,08958318 ! vesicle targeting GO:0006903 32 23 0,000 0,06995278 0,08953333 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06995278 0,08948353 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06995278 0,08943379 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06995278 0,08938411 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06995278 0,08933448 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,06995278 0,0892849 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06995278 0,08923538 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06995278 0,08918592 ! cell fate determination GO:0001709 45 23 0,000 0,06995278 0,08913651 ! pentose metabolic process GO:0019321 31 23 0,000 0,06995278 0,08908715 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06995278 0,08903785 ! spermatid development GO:0007286 33 23 0,000 0,06995278 0,0889886 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06995278 0,08893941 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06995278 0,08889027 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06995278 0,08884119 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06995278 0,08879216 ! telomere organization GO:0032200 32 23 0,000 0,06995278 0,08874319 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,06995278 0,08869426 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06995278 0,0886454 ! regulation of amine transport GO:0051952 38 23 0,000 0,06995278 0,08859658 ! liver development GO:0001889 40 23 0,000 0,06995278 0,08854782 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,07288265 0,09220577 ! initiation of viral infection GO:0019059 42 24 0,000 0,07288265 0,09215508 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,07288265 0,09210445 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,07288265 0,09205387 ! superoxide metabolic process GO:0006801 32 24 0,000 0,07288265 0,09200335 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,07288265 0,09195288 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,07288265 0,09190246 ! fat cell differentiation GO:0045444 37 24 0,000 0,07288265 0,09185211 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,07288265 0,0918018 ! sperm motility GO:0030317 27 24 0,000 0,07288265 0,09175156 ! vacuole organization GO:0007033 39 24 0,000 0,07288265 0,09170137 ! receptor metabolic process GO:0043112 37 24 0,000 0,07288265 0,09165123 ! neural crest cell development GO:0014032 39 24 0,000 0,07288265 0,09160115 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,07288265 0,09155112 ! primary neural tube formation GO:0014020 35 24 0,000 0,07288265 0,09150114 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,07288265 0,09145123 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,07288265 0,09140136 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,07288265 0,09135155 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,07288265 0,09130179 ! glutathione metabolic process GO:0006749 29 24 0,000 0,07288265 0,09125209 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,07288265 0,09120245 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,07288265 0,09115285 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,07580346 0,09475432 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,07580346 0,09470285 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,07580346 0,09465144 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,07580346 0,09460008 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,07580346 0,09454878 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,07580346 0,09449754 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,07580346 0,09444634 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,07580346 0,09439521 ! peptide transport GO:0015833 43 25 0,000 0,07580346 0,09434413 ! male gonad development GO:0008584 33 25 0,000 0,07580346 0,09429311 ! iron ion homeostasis GO:0055072 39 25 0,000 0,07580346 0,09424214 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,07580346 0,09419122 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,07580346 0,09414036 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,07580346 0,09408956 ! phospholipid transport GO:0015914 35 25 0,000 0,07580346 0,09403881 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,07580346 0,09398811 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,07580346 0,09393747 ! detection of light stimulus GO:0009583 30 25 0,000 0,07580346 0,09388689 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,07580346 0,09383636 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,07580346 0,09378588 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07871523 0,09733604 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,07871523 0,09728373 ! translational initiation GO:0006413 43 26 0,000 0,07871523 0,09723149 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,07871523 0,0971793 ! circadian rhythm GO:0007623 42 26 0,000 0,07871523 0,09712716 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07871523 0,09707508 ! post-embryonic development GO:0009791 42 26 0,000 0,07871523 0,09702306 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07871523 0,09697109 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07871523 0,09691918 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07871523 0,09686732 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,07871523 0,09681552 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,07871523 0,09676378 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07871523 0,09671209 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,07871523 0,09666045 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07871523 0,09660887 ! regulation of coagulation GO:0050818 39 26 0,000 0,07871523 0,09655735 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,08161799 0,10006471 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,08161799 0,10001139 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,08161799 0,09995814 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,08161799 0,09990494 ! membrane docking GO:0022406 39 27 0,000 0,08161799 0,0998518 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,08161799 0,09979872 ! catechol metabolic process GO:0009712 43 27 0,000 0,08161799 0,09974569 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,08161799 0,09969272 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,08161799 0,0996398 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,08161799 0,09958694 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,08161799 0,09953414 ! natural killer cell activation GO:0030101 35 27 0,000 0,08161799 0,09948139 ! lipid oxidation GO:0034440 38 27 0,000 0,08161799 0,0994287 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,08161799 0,09937607 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,08161799 0,09932349 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,08161799 0,09927096 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,08161799 0,09921849 ! gene silencing GO:0016458 41 27 0,000 0,08161799 0,09916608 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,08451178 0,10262782 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,08451178 0,10257366 ! phenol metabolic process GO:0018958 44 28 0,000 0,08451178 0,10251956 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,08451178 0,10246552 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,08451178 0,10241153 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,08451178 0,10235761 ! cell junction assembly GO:0034329 56 28 0,000 0,08451178 0,10230373 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,08451178 0,10224992 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,08451178 0,10219616 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,08451178 0,10214246 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,08451178 0,10208881 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,08451178 0,10203522 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,08451178 0,10198169 GO:0002764|immune response-regulating signal transduction, ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,08451178 0,10192821 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,08451178 0,10187479 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,08451178 0,10182142 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,08451178 0,10176811 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,08451178 0,10171486 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,08451178 0,10166166 ! placenta development GO:0001890 37 28 0,000 0,08451178 0,10160852 ! regulation of B cell activation GO:0050864 42 28 0,000 0,08451178 0,10155543 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,08739661 0,10496721 ! regulation of innate immune response GO:0045088 38 29 0,000 0,08739661 0,10491242 ! ovulation cycle process GO:0022602 41 29 0,000 0,08739661 0,1048577 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,08739661 0,10480303 ! protein targeting to membrane GO:0006612 53 29 0,000 0,08739661 0,10474841 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,08739661 0,10469386 ! mismatch repair GO:0006298 34 29 0,000 0,08739661 0,10463936 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,08739661 0,10458491 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,08739661 0,10453053 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,09027252 0,10791413 ! collagen metabolic process GO:0032963 40 30 0,000 0,09027252 0,10785807 ! organic anion transport GO:0015711 51 30 0,000 0,09027252 0,10780207 ! cholesterol transport GO:0030301 46 30 0,000 0,09027252 0,10774613 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,09027252 0,10769024 ! spindle organization GO:0007051 37 30 0,000 0,09027252 0,10763442 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,09027252 0,10757865 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,09027252 0,10752294 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,09027252 0,10746728 ! ceramide metabolic process GO:0006672 43 30 0,000 0,09027252 0,10741169 ! ovulation cycle GO:0042698 43 30 0,000 0,09027252 0,10735615 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,09027252 0,10730067 ! adult locomotory behavior GO:0008344 47 30 0,000 0,09027252 0,10724524 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,09027252 0,10718988 ! response to heat GO:0009408 41 30 0,000 0,09027252 0,10713457 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,09027252 0,10707931 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,09027252 0,10702412 ! negative regulation of secretion GO:0051048 49 31 0,000 0,09313952 0,11036626 ! glial cell differentiation GO:0010001 55 31 0,000 0,09313952 0,11030943 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,09313952 0,11025265 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,09313952 0,11019594 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,09313952 0,11013928 ! segmentation GO:0035282 41 31 0,000 0,09313952 0,11008269 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,09313952 0,11002615 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,09313952 0,10996966 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,09313952 0,10991324 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,09313952 0,10985687 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,09313952 0,10980057 ! RNA modification GO:0009451 40 31 0,000 0,09313952 0,10974432 ! regulation of muscle development GO:0048634 48 32 0,000 0,09599766 0,11305408 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,09599766 0,11299622 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,09599766 0,11293842 ! meiosis I GO:0007127 52 32 0,000 0,09599766 0,11288068 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,09599766 0,112823 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,09599766 0,11276538 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,09599766 0,11270782 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 48 32 0,000 0,09599766 0,11265032 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,09599766 0,11259287 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,09599766 0,11253548 ! cytokine production GO:0001816 44 32 0,000 0,09599766 0,11247815 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,09599766 0,11242088 ! vesicle localization GO:0051648 47 32 0,000 0,09599766 0,11236367 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,09884695 0,11563987 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,09884695 0,11558108 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,09884695 0,11552235 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,09884695 0,11546368 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,09884695 0,11540507 ! sister chromatid segregation GO:0000819 46 33 0,000 0,09884695 0,11534652 ! ear morphogenesis GO:0042471 42 33 0,000 0,09884695 0,11528803 ! cell junction organization GO:0034330 63 33 0,000 0,09884695 0,11522959 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,09884695 0,11517122 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,09884695 0,1151129 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,09884695 0,11505465 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,09884695 0,11499645 ! positive regulation of cell development GO:0010720 54 33 0,000 0,09884695 0,11493832 ! lipid homeostasis GO:0055088 55 33 0,000 0,09884695 0,11488024 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,09884695 0,11482222 ! regulation of proteolysis GO:0030162 50 33 0,000 0,09884695 0,11476425 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,09884695 0,11470635 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,09884695 0,11464851 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,10168742 0,11788361 ! mRNA catabolic process GO:0006402 48 34 0,000 0,10168742 0,11782422 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,10168742 0,11776489 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,10168742 0,11770562 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,10168742 0,11764642 ! feeding behavior GO:0007631 45 34 0,000 0,10168742 0,11758727 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,10168742 0,11752818 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,10168742 0,11746915 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,10168742 0,11741018 ! neuron migration GO:0001764 46 34 0,000 0,10168742 0,11735127 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,10168742 0,11729242 ! polyol metabolic process GO:0019751 44 34 0,000 0,10168742 0,11723362 ! aerobic respiration GO:0009060 47 34 0,000 0,10168742 0,11717489 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,10168742 0,11711621 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,10451911 0,12031729 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,10451911 0,1202571 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,10451911 0,12019697 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,10451911 0,1201369 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,10451911 0,1200769 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,10451911 0,12001695 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,10451911 0,11995706 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,10451911 0,11989723 ! pigment metabolic process GO:0042440 61 35 0,000 0,10451911 0,11983746 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,10451911 0,11977775 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,10734202 0,12295152 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 0,000 0,10734202 0,12289032 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,10734202 0,12282918 ! negative regulation of binding GO:0051100 58 36 0,000 0,10734202 0,1227681 ! organic ether metabolic process GO:0018904 46 36 0,000 0,10734202 0,12270709 ! tissue remodeling GO:0048771 62 36 0,000 0,10734202 0,12264613 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,10734202 0,12258523 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,10734202 0,1225244 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,10734202 0,12246362 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,1101562 0,12561193 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,1101562 0,12554969 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,1101562 0,1254875 ! learning GO:0007612 67 37 0,000 0,1101562 0,12542538 ! ion transmembrane transport GO:0034220 56 37 0,000 0,1101562 0,12536332 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,1101562 0,12530132 ! regulation of protein secretion GO:0050708 51 37 0,000 0,1101562 0,12523938 ! amino acid activation GO:0043038 52 37 0,000 0,1101562 0,12517751 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,1101562 0,12511569 ! gliogenesis GO:0042063 71 38 0,000 0,11296167 0,12823882 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,11296167 0,12817555 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,11296167 0,12811235 ! phagocytosis GO:0006909 60 38 0,000 0,11296167 0,12804921 ! pigmentation GO:0043473 74 38 0,000 0,11296167 0,12798613 ! maintenance of location in cell GO:0051651 69 38 0,000 0,11296167 0,12792312 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,11575846 0,13102581 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,11575846 0,13096136 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,11575846 0,13089698 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,11575846 0,13083266 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,11575846 0,1307684 ! male sex differentiation GO:0046661 53 39 0,000 0,11575846 0,1307042 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,11575846 0,13064007 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,11575846 0,130576 ! JNK cascade GO:0007254 54 39 0,000 0,11575846 0,13051199 ! cell growth GO:0016049 61 39 0,000 0,11575846 0,13044804 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,11854658 0,13352456 ! response to calcium ion GO:0051592 58 40 0,000 0,11854658 0,1334592 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,11854658 0,13339391 ! regulation of tube size GO:0035150 60 40 0,000 0,11854658 0,13332868 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,11854658 0,13326351 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,11854658 0,13319841 ! peptide metabolic process GO:0006518 56 40 0,000 0,11854658 0,13313337 ! inner ear development GO:0048839 57 40 0,000 0,11854658 0,1330684 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,11854658 0,13300348 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,11854658 0,13293864 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,11854658 0,13287385 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,11854658 0,13280913 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,12132608 0,13585686 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,12132608 0,13579074 ! glucose transport GO:0015758 52 41 0,000 0,12132608 0,1357247 ! endosome transport GO:0016197 71 41 0,000 0,12132608 0,13565872 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,12132608 0,1355928 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,12132608 0,13552695 ! biopolymer methylation GO:0043414 62 41 0,000 0,12132608 0,13546116 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,12132608 0,13539543 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,12409697 0,13842048 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,12409697 0,13835338 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,12409697 0,13828635 ! hexose transport GO:0008645 54 42 0,000 0,12409697 0,13821938 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,12409697 0,13815248 ! excretion GO:0007588 63 42 0,000 0,12409697 0,13808564 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,12409697 0,13801887 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,12409697 0,13795216 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,12409697 0,13788552 ! regulation of cell shape GO:0008360 78 42 0,000 0,12409697 0,13781894 ! positive regulation of binding GO:0051099 59 43 0,000 0,12685928 0,14081869 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,12685928 0,14075076 ! leukocyte migration GO:0050900 60 43 0,000 0,12685928 0,1406829 ! neuromuscular process GO:0050905 79 43 0,000 0,12685928 0,1406151 ! tRNA processing GO:0008033 49 43 0,000 0,12685928 0,14054737 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,12685928 0,1404797 ! vesicle organization GO:0016050 79 43 0,000 0,12685928 0,1404121 ! methylation GO:0032259 64 43 0,000 0,12685928 0,14034456 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,12961303 0,1433221 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,12961303 0,14325323 ! glycolysis GO:0006096 53 44 0,000 0,12961303 0,14318442 ! regulation of ion transport GO:0043269 57 44 0,000 0,12961303 0,14311569 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,12961303 0,14304701 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,12961303 0,1429784 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,12961303 0,14290986 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,12961303 0,14284139 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,12961303 0,14277298 ! RNA catabolic process GO:0006401 64 45 0,000 0,13235826 0,14572714 ! positive regulation of defense response GO:0031349 59 45 0,000 0,13235826 0,14565741 ! regulation of translational initiation GO:0006446 64 45 0,000 0,13235826 0,14558776 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,13235826 0,14551816 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,13235826 0,14544864 ! cell recognition GO:0008037 58 45 0,000 0,13235826 0,14537918 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,13509499 0,1483143 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,13509499 0,14824354 ! cell redox homeostasis GO:0045454 63 46 0,000 0,13509499 0,14817285 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,13509499 0,14810222 ! histone modification GO:0016570 68 46 0,000 0,13509499 0,14803167 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,13509499 0,14796117 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,13782324 0,15087741 ! viral infectious cycle GO:0019058 71 47 0,000 0,13782324 0,15080563 ! endocrine system development GO:0035270 83 47 0,000 0,13782324 0,15073392 ! covalent chromatin modification GO:0016569 75 47 0,000 0,13782324 0,15066228 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,13782324 0,15059071 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,13782324 0,1505192 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,13782324 0,15044777 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,13782324 0,1503764 ! chloride transport GO:0006821 67 48 0,000 0,14054304 0,15327121 ! response to temperature stimulus GO:0009266 62 48 0,000 0,14054304 0,15319857 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,14054304 0,153126 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,14054304 0,1530535 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,14054304 0,15298106 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,14054304 0,1529087 ! nuclear export GO:0051168 69 48 0,000 0,14054304 0,1528364 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,14054304 0,15276417 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,14325441 0,15563777 ! sensory perception of smell GO:0007608 61 49 0,000 0,14325441 0,15556428 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,14325441 0,15549087 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,14325441 0,15541752 ! RNA elongation GO:0006354 62 49 0,000 0,14325441 0,15534425 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,14325441 0,15527104 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,14325441 0,1551979 ! cartilage development GO:0051216 70 49 0,000 0,14325441 0,15512483 ! maintenance of location GO:0051235 84 49 0,000 0,14325441 0,15505183 ! regulation of actin filament length GO:0030832 72 50 0,000 0,14595739 0,1579031 ! ear development GO:0043583 72 50 0,000 0,14595739 0,15782887 ! membrane fusion GO:0006944 80 50 0,000 0,14595739 0,1577547 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,14595739 0,1576806 ! proton transport GO:0015992 75 50 0,000 0,14595739 0,15760657 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,14595739 0,15753261 ! positive regulation of secretion GO:0051047 71 51 0,000 0,14865199 0,16036566 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,14865199 0,16029048 ! hydrogen transport GO:0006818 77 51 0,000 0,14865199 0,16021536 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,14865199 0,16014032 GO:0010863|positive regulation of phospholipase C activity, ! adult behavior GO:0030534 80 51 0,000 0,14865199 0,16006535 ! transition metal ion transport GO:0000041 74 52 0,000 0,15133825 0,1628816 ! regulation of cellular component size GO:0032535 74 52 0,000 0,15133825 0,16280542 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,15133825 0,1627293 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,15133825 0,16265326 ! establishment of organelle localization GO:0051656 85 52 0,000 0,15133825 0,16257729 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,15401619 0,16537686 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,15401619 0,16529969 ! single fertilization GO:0007338 59 53 0,000 0,15401619 0,16522259 ! cell projection assembly GO:0030031 76 53 0,000 0,15401619 0,16514556 ! amino acid transport GO:0006865 84 54 0,000 0,15668582 0,16792982 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,15668582 0,1678516 ! regulation of mitosis GO:0007088 84 54 0,000 0,15668582 0,16777346 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,15668582 0,16769539 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,15668582 0,16761739 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,15668582 0,16753947 ! detection of external stimulus GO:0009581 66 54 0,000 0,15668582 0,16746161 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,15668582 0,16738383 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,15668582 0,16730612 ! exocytosis GO:0006887 74 55 0,000 0,15934719 0,17006893 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,15934719 0,16999004 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,15934719 0,16991123 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,16200031 0,1726602 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,16464521 0,17539786 ! carbohydrate transport GO:0008643 74 57 0,000 0,16464521 0,17531665 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,16464521 0,17523553 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,16464521 0,17515447 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,16464521 0,1750735 ! secondary metabolic process GO:0019748 84 57 0,000 0,16464521 0,17499259 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,16728191 0,17771288 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,16728191 0,17763083 ! actin filament organization GO:0007015 95 59 0,000 0,16991044 0,18033872 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,16991044 0,18025554 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,16991044 0,18017243 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,17253082 0,18286677 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,17253082 0,18278253 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,17253082 0,18269838 ! fertilization GO:0009566 68 60 0,000 0,17253082 0,1826143 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,17253082 0,1825303 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,17514308 0,18520877 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,17514308 0,18512366 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,17514308 0,18503862 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,17514308 0,18495366 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,17514308 0,18486878 ! extracellular matrix organization GO:0030198 103 61 0,000 0,17514308 0,18478398 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,17514308 0,18469926 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,17514308 0,18461461 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,17514308 0,18453004 ! amine catabolic process GO:0009310 90 62 0,000 0,17774724 0,18718803 ! neurotransmitter transport GO:0006836 81 62 0,000 0,17774724 0,18710236 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,17774724 0,18701677 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,17774724 0,18693126 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,17774724 0,18684582 ! organelle localization GO:0051640 96 62 0,000 0,17774724 0,18676046 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,18034333 0,18940167 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,18034333 0,18931523 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,18034333 0,18922886 ! regulation of lipase activity GO:0060191 109 63 0,000 0,18034333 0,18914257 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,18293138 0,19176945 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,18293138 0,19168208 ! hexose catabolic process GO:0019320 82 64 0,000 0,18293138 0,19159479 ! adaptive immune response GO:0002250 94 64 0,000 0,18293138 0,19150758 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,18551139 0,1941202 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,18551139 0,19403193 ! defense response to bacterium GO:0042742 73 65 0,000 0,18551139 0,19394373 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,18551139 0,19385561 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,18551139 0,19376758 ! activation of immune response GO:0002253 83 65 0,000 0,18551139 0,19367962 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,18808341 0,1962758 ! antigen processing and presentation GO:0019882 96 66 0,000 0,18808341 0,19618678 ! regulation of immune effector process GO:0002697 101 66 0,000 0,18808341 0,19609785 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,19064746 0,19868109 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,19064746 0,1985911 ! learning or memory GO:0007611 123 68 0,000 0,19320355 0,2011626 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,19320355 0,20107157 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,19320355 0,20098063 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,19320355 0,20088977 ! rhythmic process GO:0048511 105 68 0,000 0,19320355 0,20079899 ! inorganic anion transport GO:0015698 93 68 0,000 0,19320355 0,2007083 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,19575172 0,20326364 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,19575172 0,20317191 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,19575172 0,20308027 ! humoral immune response GO:0006959 86 70 0,000 0,19829199 0,20562289 ! amine transport GO:0015837 101 70 0,000 0,19829199 0,20553023 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,19829199 0,20543765 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,19829199 0,20534515 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,20082438 0,20787402 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,20082438 0,20778051 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,20082438 0,20768708 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,20082438 0,20759374 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,20334891 0,21010894 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,20334891 0,21001459 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,20334891 0,20992033 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,20586561 0,21242302 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,20837451 0,21491542 ! digestion GO:0007586 97 74 0,000 0,20837451 0,21481908 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,20837451 0,21472284 ! blood coagulation GO:0007596 116 75 0,000 0,21087563 0,21720284 GO:0050817|coagulation, ! regulation of ligase activity GO:0051340 114 75 0,000 0,21087563 0,21710561 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,21087563 0,21700847 ! amine biosynthetic process GO:0009309 97 76 0,000 0,21336898 0,21947614 ! tRNA metabolic process GO:0006399 95 76 0,000 0,21336898 0,21937803 ! response to unfolded protein GO:0006986 99 76 0,000 0,21336898 0,21928001 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,21336898 0,21918207 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,2158546 0,22163642 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,2158546 0,22153752 ! regulation of DNA binding GO:0051101 119 77 0,000 0,2158546 0,22143871 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,2158546 0,22133998 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,2158546 0,22124135 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,2158546 0,2211428 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,21833251 0,22358182 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,21833251 0,22348232 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,21833251 0,22338291 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,22080273 0,22580982 ! cellular respiration GO:0045333 107 79 0,000 0,22080273 0,22570946 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,22080273 0,22560919 ! regulation of lyase activity GO:0051339 133 79 0,000 0,22080273 0,22550901 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,22080273 0,22540891 ! chromatin assembly GO:0031497 102 80 0,000 0,22326529 0,22782172 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,22326529 0,22772069 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,22326529 0,22761975 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,22326529 0,2275189 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,2257202 0,22991872 ! hemostasis GO:0007599 125 81 0,000 0,2257202 0,22981694 ! response to protein stimulus GO:0051789 111 81 0,000 0,2257202 0,22971525 ! regulation of neurological system process GO:0031644 122 81 0,000 0,2257202 0,22961365 ! vitamin metabolic process GO:0006766 103 81 0,000 0,2257202 0,22951214 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,2257202 0,22941072 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,2281675 0,2317956 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,2306072 0,23417066 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,2306072 0,23406732 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,23303932 0,2364316 ! sterol metabolic process GO:0016125 120 84 0,000 0,23303932 0,23632736 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,2354639 0,23868091 ! rRNA metabolic process GO:0016072 107 85 0,000 0,2354639 0,23857576 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,2354639 0,23847071 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,23788096 0,24081259 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,23788096 0,24070664 ! nucleosome organization GO:0034728 114 87 0,000 0,24029051 0,24303789 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,24029051 0,24293106 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,24029051 0,24282433 ! female pregnancy GO:0007565 130 87 0,000 0,24029051 0,24271769 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,24269258 0,24503641 ! interphase GO:0051325 159 88 0,000 0,24269258 0,24492889 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,24269258 0,24482146 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,24508719 0,24712869 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,24508719 0,2470204 ! hormone metabolic process GO:0042445 121 90 0,000 0,24747437 0,24931715 ! ATP metabolic process GO:0046034 137 91 0,000 0,24985414 0,25160443 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,25222652 0,25388227 ! positive regulation of immune response GO:0050778 121 92 0,000 0,25222652 0,25377121 ! sulfur metabolic process GO:0006790 118 92 0,000 0,25222652 0,25366025 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,25459153 0,2559268 ! electron transport chain GO:0022900 123 94 0,000 0,25694919 0,25818399 ! regulation of binding GO:0051098 151 95 0,000 0,25929954 0,26043185 ! angiogenesis GO:0001525 149 95 0,000 0,25929954 0,26031818 ! carboxylic acid transport GO:0046942 147 95 0,000 0,25929954 0,2602046 GO:0015849|organic acid transport, ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,26397835 0,26478422 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,26862814 0,26933075 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,26862814 0,26921339 ! regulation of translation GO:0006417 151 100 0,000 0,27094221 0,27141424 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,27094221 0,27129608 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,27094221 0,27117802 ! divalent metal ion transport GO:0070838 171 100 0,000 0,27094221 0,27106007 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,27094221 0,27094221