pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6369-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 25 25 4,000 4,64E-08 8,552E-05 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 4,000 7,01E-08 6,46E-05 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 3,000 8,233E-08 5,058E-05 GO:0032388|positive regulation of intracellular transport, ! regulation of intracellular transport GO:0032386 31 31 4,000 1,458E-07 6,719E-05 ! ER overload response GO:0006983 6 6 2,000 1,336E-06 4,923E-04 ! regulation of protein transport GO:0051223 53 53 4,000 2,31E-06 7,095E-04 GO:0070201|regulation of establishment of protein localization, ! regulation of mRNA processing GO:0050684 7 7 2,000 2,331E-06 6,136E-04 ! regulation of protein localization GO:0032880 58 57 4,000 3,331E-06 7,674E-04 ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 5,562E-06 1,139E-03 ! positive regulation of protein transport GO:0051222 29 29 3,000 5,623E-06 1,036E-03 ! positive regulation of transport GO:0051050 71 70 4,000 9,27E-06 1,553E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 1,872E-05 2,876E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,872E-05 2,654E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,872E-05 2,465E-03 ! protein oligomerization GO:0051259 39 39 3,000 1,891E-05 2,324E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 2,405E-05 2,77E-03 ! heart development GO:0007507 90 87 4,000 2,693E-05 2,919E-03 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 2,962E-05 3,033E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 2,962E-05 2,873E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 3,367E-05 3,103E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 3,635E-05 3,19E-03 ! pattern specification process GO:0007389 96 94 4,000 3,919E-05 3,283E-03 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 4,401E-05 3,527E-03 ! anterior/posterior pattern formation GO:0009952 51 50 3,000 5,129E-05 3,939E-03 ! cell fate commitment GO:0045165 52 52 3,000 5,994E-05 4,419E-03 ! mammary gland development GO:0030879 23 21 2,000 8,512E-05 6,033E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 8,512E-05 5,81E-03 ! mitochondrial transport GO:0006839 24 24 2,000 1,284E-04 8,454E-03 ! glucan metabolic process GO:0044042 25 24 2,000 1,284E-04 8,162E-03 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,455E-04 8,941E-03 ! gastrulation GO:0007369 25 25 2,000 1,455E-04 8,652E-03 ! heart morphogenesis GO:0003007 25 25 2,000 1,455E-04 8,382E-03 ! neuron fate specification GO:0048665 5 5 1,000 1,702E-04 9,507E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,702E-04 9,227E-03 ! forebrain regionalization GO:0021871 5 5 1,000 1,702E-04 8,964E-03 ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 1,702E-04 8,715E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,702E-04 8,479E-03 ! positive regulation of phagocytosis GO:0050766 5 5 1,000 1,702E-04 8,256E-03 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 1,000 1,702E-04 8,044E-03 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 1,702E-04 7,843E-03 GO:0021517|ventral spinal cord development, ! T cell lineage commitment GO:0002360 5 5 1,000 1,702E-04 7,652E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,702E-04 7,47E-03 ! sarcomere organization GO:0045214 5 5 1,000 1,702E-04 7,296E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 1,702E-04 7,13E-03 GO:0007439|ectodermal gut development, ! embryonic gut development GO:0048566 5 5 1,000 1,702E-04 6,972E-03 ! positive regulation of actin filament bundle formation GO:0032233 5 5 1,000 1,702E-04 6,82E-03 ! regionalization GO:0003002 70 69 3,000 1,822E-04 7,143E-03 ! energy reserve metabolic process GO:0006112 28 27 2,000 1,84E-04 7,066E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 2,055E-04 7,731E-03 ! regulation of ossification GO:0030278 30 30 2,000 2,533E-04 9,336E-03 ! virus-host interaction GO:0019048 6 6 1,000 2,547E-04 9,203E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,547E-04 9,026E-03 ! positive regulation of heart contraction GO:0045823 6 6 1,000 2,547E-04 8,856E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,547E-04 8,692E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of heart rate GO:0002027 6 6 1,000 2,547E-04 8,534E-03 ! Rac protein signal transduction GO:0016601 6 6 1,000 2,547E-04 8,381E-03 ! ruffle organization GO:0031529 6 6 1,000 2,547E-04 8,234E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 2,547E-04 8,092E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 2,547E-04 7,955E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,547E-04 7,823E-03 ! regulation of phagocytosis GO:0050764 6 6 1,000 2,547E-04 7,694E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,547E-04 7,57E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,547E-04 7,45E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,547E-04 7,334E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,547E-04 7,221E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 2,796E-04 7,808E-03 ! positive regulation of blood pressure GO:0045777 7 7 1,000 3,556E-04 9,782E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 3,556E-04 9,638E-03 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 3,556E-04 9,498E-03 ! digestive system development GO:0055123 7 7 1,000 3,556E-04 9,363E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! cell differentiation in spinal cord GO:0021515 7 7 1,000 3,556E-04 9,231E-03 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 3,556E-04 9,103E-03 GO:0033619|membrane protein proteolysis, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,556E-04 8,978E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 3,556E-04 8,857E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,556E-04 8,739E-03 ! myofibril assembly GO:0030239 7 7 1,000 3,556E-04 8,624E-03 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 3,556E-04 8,512E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cranial nerve development GO:0021545 7 7 1,000 3,556E-04 8,402E-03 ! response to gamma radiation GO:0010332 8 7 1,000 3,556E-04 8,296E-03 ! regulation of ATPase activity GO:0043462 7 7 1,000 3,556E-04 8,192E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,556E-04 8,091E-03 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 3,691E-04 8,296E-03 ! regulation of bone remodeling GO:0046850 34 34 2,000 3,691E-04 8,196E-03 ! regulation of tissue remodeling GO:0034103 35 35 2,000 4,026E-04 8,832E-03 ! embryonic limb morphogenesis GO:0030326 36 36 2,000 4,379E-04 9,495E-03 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of bone remodeling GO:0046851 8 8 1,000 4,729E-04 0,01013451 ! cardiac muscle contraction GO:0060048 8 8 1,000 4,729E-04 0,01001802 ! regulation of stress fiber formation GO:0051492 9 8 1,000 4,729E-04 9,904E-03 ! sex determination GO:0007530 8 8 1,000 4,729E-04 9,793E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 4,729E-04 9,684E-03 ! embryonic digit morphogenesis GO:0042733 8 8 1,000 4,729E-04 9,578E-03 ! muscle cell development GO:0055001 8 8 1,000 4,729E-04 9,474E-03 ! gastrulation with mouth forming second GO:0001702 8 8 1,000 4,729E-04 9,372E-03 ! mRNA cleavage GO:0006379 8 8 1,000 4,729E-04 9,272E-03 ! peptidyl-serine modification GO:0018209 8 8 1,000 4,729E-04 9,174E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 4,729E-04 9,079E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 4,729E-04 8,985E-03 ! limb development GO:0060173 39 39 2,000 5,558E-04 0,01045214 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! tissue morphogenesis GO:0048729 94 93 3,000 5,737E-04 0,01068025 ! embryonic pattern specification GO:0009880 10 9 1,000 6,064E-04 0,01117658 ! cortical actin cytoskeleton organization GO:0030866 10 9 1,000 6,064E-04 0,01106592 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 6,064E-04 0,01095743 GO:0060675|ureteric bud morphogenesis, ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 1,000 6,064E-04 0,01085105 ! regulation of cellular pH GO:0030641 9 9 1,000 6,064E-04 0,01074671 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 6,064E-04 0,01064436 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 6,064E-04 0,01054394 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 6,064E-04 0,0104454 ! defense response to virus GO:0051607 9 9 1,000 6,064E-04 0,01034869 ! actin filament-based movement GO:0030048 9 9 1,000 6,064E-04 0,01025374 ! regulation of caspase activity GO:0043281 41 41 2,000 6,446E-04 0,01080034 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 6,922E-04 0,01149377 ! mitochondrion organization GO:0007005 44 43 2,000 7,421E-04 0,01221086 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 7,561E-04 0,01233117 ! neuron maturation GO:0042551 10 10 1,000 7,561E-04 0,012223 ! cortical cytoskeleton organization GO:0030865 11 10 1,000 7,561E-04 0,01211671 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 7,561E-04 0,01201226 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 7,561E-04 0,01190959 ! regulation of survival gene product expression GO:0045884 10 10 1,000 7,561E-04 0,01180866 ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 7,561E-04 0,01170943 ! neuromuscular junction development GO:0007528 10 10 1,000 7,561E-04 0,01161185 ! nerve development GO:0021675 10 10 1,000 7,561E-04 0,01151589 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 7,561E-04 0,01142149 ! gut development GO:0048565 10 10 1,000 7,561E-04 0,01132863 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 7,561E-04 0,01123728 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 7,561E-04 0,01114738 ! protein import into nucleus GO:0006606 44 44 2,000 7,941E-04 0,01161538 ! nuclear import GO:0051170 45 45 2,000 8,484E-04 0,01231215 ! regulation of peptidase activity GO:0052547 46 46 2,000 9,051E-04 0,01303131 ! regulation of membrane potential GO:0042391 46 46 2,000 9,051E-04 0,01293029 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 9,217E-04 0,01306633 ! heart contraction GO:0060047 11 11 1,000 9,217E-04 0,01296658 GO:0003015|heart process, ! spinal cord development GO:0021510 11 11 1,000 9,217E-04 0,01286835 ! cellular response to starvation GO:0009267 11 11 1,000 9,217E-04 0,0127716 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 9,217E-04 0,01267629 ! apoptotic nuclear changes GO:0030262 11 11 1,000 9,217E-04 0,01258239 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 9,217E-04 0,01248987 ! G1/S transition checkpoint GO:0031575 12 11 1,000 9,217E-04 0,0123987 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 1,000 9,217E-04 0,01230886 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 1,000 9,217E-04 0,0122203 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 9,217E-04 0,01213302 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 9,217E-04 0,01204697 ! proximal/distal pattern formation GO:0009954 11 11 1,000 9,217E-04 0,01196213 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 9,217E-04 0,01187848 ! regulation of catabolic process GO:0009894 48 47 2,000 9,64E-04 0,01233819 ! protein localization in nucleus GO:0034504 48 48 2,000 1,025E-03 0,01303304 ! ossification GO:0001503 50 49 2,000 1,089E-03 0,01374897 GO:0060348|bone development, ! gland development GO:0048732 51 49 2,000 1,089E-03 0,01365544 ! cell cycle arrest GO:0007050 49 49 2,000 1,089E-03 0,01356318 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 1,089E-03 0,01347215 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,103E-03 0,01355349 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 1,103E-03 0,01346373 ! actomyosin structure organization GO:0031032 12 12 1,000 1,103E-03 0,01337515 ! positive regulation of endocytosis GO:0045807 12 12 1,000 1,103E-03 0,01328773 ! glycoprotein catabolic process GO:0006516 13 12 1,000 1,103E-03 0,01320145 ! acute-phase response GO:0006953 12 12 1,000 1,103E-03 0,01311628 ! osteoblast differentiation GO:0001649 12 12 1,000 1,103E-03 0,0130322 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,103E-03 0,01294919 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 1,155E-03 0,0134775 ! regulation of neurogenesis GO:0050767 51 50 2,000 1,155E-03 0,01339274 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,3E-03 0,01497743 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 1,3E-03 0,01488441 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,3E-03 0,01479253 ! ureteric bud development GO:0001657 13 13 1,000 1,3E-03 0,01470178 ! cell aging GO:0007569 13 13 1,000 1,3E-03 0,01461213 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,3E-03 0,01452357 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 1,3E-03 0,01443608 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,3E-03 0,01434964 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,3E-03 0,01426422 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 1,3E-03 0,01417982 ! tissue homeostasis GO:0001894 13 13 1,000 1,3E-03 0,01409641 GO:0048871|multicellular organismal homeostasis, ! neuron fate commitment GO:0048663 14 14 1,000 1,513E-03 0,01630695 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 1,513E-03 0,01621214 ! base-excision repair GO:0006284 14 14 1,000 1,513E-03 0,01611843 ! formation of primary germ layer GO:0001704 14 14 1,000 1,513E-03 0,0160258 GO:0001707|mesoderm formation, ! positive regulation of osteoblast differentiation GO:0045669 14 14 1,000 1,513E-03 0,01593422 ! in utero embryonic development GO:0001701 55 55 2,000 1,525E-03 0,01596748 ! regulation of cell adhesion GO:0030155 56 55 2,000 1,525E-03 0,01587727 ! regulation of nervous system development GO:0051960 57 56 2,000 1,607E-03 0,01663463 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,741E-03 0,01792787 ! striated muscle cell differentiation GO:0051146 16 15 1,000 1,741E-03 0,01782827 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 1,741E-03 0,01772977 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,741E-03 0,01763236 ! mesoderm morphogenesis GO:0048332 15 15 1,000 1,741E-03 0,01753601 ! response to starvation GO:0042594 15 15 1,000 1,741E-03 0,0174407 ! response to ionizing radiation GO:0010212 16 15 1,000 1,741E-03 0,01734643 ! regulation of biomineral formation GO:0070167 15 15 1,000 1,741E-03 0,01725317 GO:0030500|regulation of bone mineralization, ! negative regulation of cell activation GO:0050866 15 15 1,000 1,741E-03 0,0171609 ! protein homooligomerization GO:0051260 15 15 1,000 1,741E-03 0,01706962 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 1,868E-03 0,01821788 ! regulation of cell development GO:0060284 60 59 2,000 1,868E-03 0,018122 ! protein localization in organelle GO:0033365 59 59 2,000 1,868E-03 0,01802712 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 1,985E-03 0,01905187 ! spliceosomal snRNP biogenesis GO:0000387 16 16 1,000 1,985E-03 0,01895316 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,985E-03 0,01885546 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 1,985E-03 0,01875877 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 1,985E-03 0,01866306 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 1,985E-03 0,01856832 ! cell fate specification GO:0001708 16 16 1,000 1,985E-03 0,01847454 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,985E-03 0,01838171 ! protein import GO:0017038 62 62 2,000 2,155E-03 0,01985933 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 2,244E-03 0,0205715 ! myelination GO:0042552 17 17 1,000 2,244E-03 0,02046966 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 2,244E-03 0,02036883 ! negative regulation of cell development GO:0010721 18 17 1,000 2,244E-03 0,02026898 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 2,244E-03 0,02017011 ! myeloid leukocyte activation GO:0002274 18 17 1,000 2,244E-03 0,02007219 ! embryonic organ development GO:0048568 17 17 1,000 2,244E-03 0,01997523 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 2,468E-03 0,02186807 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,517E-03 0,02219903 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,517E-03 0,02209332 ! striated muscle contraction GO:0006941 18 18 1,000 2,517E-03 0,02198861 ! telencephalon development GO:0021537 19 18 1,000 2,517E-03 0,02188489 ! B cell differentiation GO:0030183 18 18 1,000 2,517E-03 0,02178215 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,517E-03 0,02168036 ! ensheathment of neurons GO:0007272 18 18 1,000 2,517E-03 0,02157952 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 1,000 2,517E-03 0,02147962 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,517E-03 0,02138063 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 2,578E-03 0,02179684 ! polysaccharide metabolic process GO:0005976 69 66 2,000 2,578E-03 0,02169731 ! striated muscle tissue development GO:0014706 69 67 2,000 2,691E-03 0,02254733 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 2,691E-03 0,02244531 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,806E-03 0,02329689 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,806E-03 0,02319242 ! regulation of pH GO:0006885 19 19 1,000 2,806E-03 0,02308888 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 2,806E-03 0,02298627 ! metanephros development GO:0001656 19 19 1,000 2,806E-03 0,02288456 ! cellular response to oxidative stress GO:0034599 19 19 1,000 2,806E-03 0,02278375 ! peripheral nervous system development GO:0007422 19 19 1,000 2,806E-03 0,02268382 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 2,806E-03 0,02258476 ! eye morphogenesis GO:0048592 19 19 1,000 2,806E-03 0,02248657 ! wound healing GO:0042060 74 70 2,000 3,05E-03 0,02433041 ! muscle tissue development GO:0060537 72 70 2,000 3,05E-03 0,02422554 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 3,11E-03 0,02459908 ! neural tube development GO:0021915 21 20 1,000 3,11E-03 0,02449395 ! nucleus organization GO:0006997 20 20 1,000 3,11E-03 0,02438972 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 3,11E-03 0,02428638 ! chromatin remodeling GO:0006338 20 20 1,000 3,11E-03 0,0241839 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 3,11E-03 0,02408229 ! regulation of cell migration GO:0030334 71 71 2,000 3,175E-03 0,02448423 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 3,304E-03 0,02537055 ! Notch signaling pathway GO:0007219 22 21 1,000 3,428E-03 0,02621741 ! DNA integrity checkpoint GO:0031570 21 21 1,000 3,428E-03 0,02610908 ! regulation of action potential in neuron GO:0019228 21 21 1,000 3,428E-03 0,02600163 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,428E-03 0,02589507 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 3,428E-03 0,02578937 ! negative regulation of protein transport GO:0051224 21 21 1,000 3,428E-03 0,02568454 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 3,761E-03 0,02806528 ! odontogenesis GO:0042476 22 22 1,000 3,761E-03 0,02795211 ! embryonic skeletal system development GO:0048706 22 22 1,000 3,761E-03 0,02783986 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 3,761E-03 0,0277285 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 3,995E-03 0,02933685 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 4,109E-03 0,03004978 ! positive regulation of growth GO:0045927 23 23 1,000 4,109E-03 0,02993101 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 4,109E-03 0,02981317 ! regulation of locomotion GO:0040012 79 79 2,000 4,295E-03 0,03104147 ! nuclear transport GO:0051169 79 79 2,000 4,295E-03 0,03092022 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 2,000 4,295E-03 0,0307999 ! regulation of action potential GO:0001508 24 24 1,000 4,471E-03 0,03193581 ! glucose homeostasis GO:0042593 24 24 1,000 4,471E-03 0,03181251 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 4,471E-03 0,03169015 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 4,471E-03 0,03156874 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 4,471E-03 0,03144824 ! MAPKKK cascade GO:0000165 82 81 2,000 4,608E-03 0,0322898 ! cellular component disassembly GO:0022411 26 25 1,000 4,847E-03 0,03383557 ! regulation of T cell proliferation GO:0042129 25 25 1,000 4,847E-03 0,03370789 ! regulation of endocytosis GO:0030100 25 25 1,000 4,847E-03 0,03358116 ! negative regulation of immune system process GO:0002683 25 25 1,000 4,847E-03 0,03345539 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 5,237E-03 0,03601409 ! negative regulation of cell migration GO:0030336 26 26 1,000 5,237E-03 0,03588021 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 5,237E-03 0,03574732 ! regulation of T cell differentiation GO:0045580 26 26 1,000 5,237E-03 0,03561541 ! double-strand break repair GO:0006302 27 26 1,000 5,237E-03 0,03548447 ! response to insulin stimulus GO:0032868 28 26 1,000 5,237E-03 0,03535449 ! synapse organization GO:0050808 26 26 1,000 5,237E-03 0,03522546 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 5,45E-03 0,03652222 ! activation of caspase activity GO:0006919 27 27 1,000 5,641E-03 0,03766951 ! mesenchymal cell development GO:0014031 29 27 1,000 5,641E-03 0,03753352 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! positive regulation of transferase activity GO:0051347 91 88 2,000 5,811E-03 0,03852115 GO:0033674|positive regulation of kinase activity, ! regulation of muscle contraction GO:0006937 28 28 1,000 6,059E-03 0,04002652 ! developmental growth GO:0048589 28 28 1,000 6,059E-03 0,03988357 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 6,059E-03 0,03974163 ! brain development GO:0007420 91 90 2,000 6,186E-03 0,04042599 ! viral reproductive process GO:0022415 29 29 1,000 6,491E-03 0,04227352 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 6,491E-03 0,04212467 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 6,491E-03 0,04197686 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 6,491E-03 0,04183009 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 1,000 6,491E-03 0,04168434 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 6,575E-03 0,0420751 ! response to reactive oxygen species GO:0000302 31 30 1,000 6,937E-03 0,04423734 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 6,937E-03 0,0440848 GO:0043280|positive regulation of caspase activity, ! skeletal system morphogenesis GO:0048705 31 30 1,000 6,937E-03 0,04393331 ! regulation of inflammatory response GO:0050727 30 30 1,000 6,937E-03 0,04378285 ! skeletal muscle fiber development GO:0048741 31 31 1,000 7,396E-03 0,04652132 ! B cell activation GO:0042113 31 31 1,000 7,396E-03 0,04636308 ! aging GO:0007568 32 31 1,000 7,396E-03 0,04620592 ! regulation of heart contraction GO:0008016 31 31 1,000 7,396E-03 0,04604982 ! camera-type eye development GO:0043010 31 31 1,000 7,396E-03 0,04589477 ! negative regulation of cell motion GO:0051271 31 31 1,000 7,396E-03 0,04574076 ! endocytosis GO:0006897 99 98 2,000 7,83E-03 0,04826148 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 2,000 7,83E-03 0,04810061 ! negative regulation of cell growth GO:0030308 32 32 1,000 7,869E-03 0,04817827 ! muscle fiber development GO:0048747 32 32 1,000 7,869E-03 0,04801874 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 7,869E-03 0,04786026 ! cell maturation GO:0048469 32 32 1,000 7,869E-03 0,04770283 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 7,869E-03 0,04754642 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 7,869E-03 0,04739104 ! kidney development GO:0001822 32 32 1,000 7,869E-03 0,04723667 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 7,869E-03 0,04708331 ! muscle organ development GO:0007517 102 100 2,000 8,277E-03 0,0493695 ! negative regulation of cell size GO:0045792 33 33 1,000 8,354E-03 0,04966813 ! regulation of neuron differentiation GO:0045664 34 33 1,000 8,354E-03 0,04950843 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 8,354E-03 0,04934975 ! regulation of synaptic transmission GO:0050804 33 33 1,000 8,354E-03 0,04919208 ! regulation of angiogenesis GO:0045765 35 34 1,000 8,853E-03 0,05196473 ! response to metal ion GO:0010038 34 34 1,000 8,853E-03 0,05179976 ! muscle cell differentiation GO:0042692 35 34 1,000 8,853E-03 0,05163584 ! regulation of protein catabolic process GO:0042176 35 34 1,000 8,853E-03 0,05147295 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 8,853E-03 0,05131108 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 8,853E-03 0,05115023 ! viral reproduction GO:0016032 34 34 1,000 8,853E-03 0,05099039 ! acute inflammatory response GO:0002526 35 35 1,000 9,366E-03 0,05377216 ! mesoderm development GO:0007498 35 35 1,000 9,366E-03 0,05360517 ! response to inorganic substance GO:0010035 36 36 1,000 9,891E-03 0,05643571 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 9,891E-03 0,05626152 ! positive regulation of cell migration GO:0030335 36 36 1,000 9,891E-03 0,05608841 ! positive regulation of organelle organization GO:0010638 36 36 1,000 9,891E-03 0,05591636 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 9,891E-03 0,05574536 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,01042883 0,05859856 ! response to drug GO:0042493 37 37 1,000 0,01042883 0,05842045 ! lung development GO:0030324 38 37 1,000 0,01042883 0,05824342 ! eye development GO:0001654 37 37 1,000 0,01042883 0,05806746 ! negative regulation of growth GO:0045926 37 37 1,000 0,01042883 0,05789256 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01042883 0,0577187 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01042883 0,05754589 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,01097962 0,06040432 ! axon guidance GO:0007411 39 38 1,000 0,01097962 0,06022454 ! regulation of neurological system process GO:0031644 38 38 1,000 0,01097962 0,06004584 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01097962 0,05986819 ! chromosome segregation GO:0007059 38 38 1,000 0,01097962 0,05969158 ! urogenital system development GO:0001655 38 38 1,000 0,01097962 0,05951602 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01154307 0,06238676 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01154307 0,06220435 ! respiratory system development GO:0060541 40 39 1,000 0,01154307 0,06202299 ! developmental maturation GO:0021700 39 39 1,000 0,01154307 0,06184269 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01154307 0,06166344 ! positive regulation of cell motion GO:0051272 39 39 1,000 0,01154307 0,06148522 ! respiratory tube development GO:0030323 40 39 1,000 0,01154307 0,06130803 ! DNA catabolic process GO:0006308 41 40 1,000 0,01211907 0,06418232 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,01211907 0,06399842 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01211907 0,06381556 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,0127075 0,06672345 ! protein ubiquitination GO:0016567 43 42 1,000 0,01330827 0,06967936 ! forebrain development GO:0030900 43 42 1,000 0,01330827 0,06948197 ! mRNA transport GO:0051028 44 44 1,000 0,01454635 0,07573145 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,01518347 0,07882572 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,01518347 0,0786043 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01518347 0,07838412 ! protein processing GO:0016485 45 45 1,000 0,01518347 0,07816517 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,01583249 0,08127931 ! tube morphogenesis GO:0035239 47 46 1,000 0,01583249 0,08105354 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01583249 0,08082901 ! regulation of blood pressure GO:0008217 48 47 1,000 0,01649331 0,08397007 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,01649331 0,08373875 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01784994 0,09037757 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01784994 0,09012996 GO:0060538|skeletal muscle organ development, ! regulation of defense response GO:0031347 50 50 1,000 0,01854554 0,09338644 ! negative regulation of transport GO:0051051 51 50 1,000 0,01854554 0,09313198 ! RNA transport GO:0050658 50 50 1,000 0,01854554 0,0928789 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 1,000 0,01854554 0,0926272 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,01854554 0,09237686 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01854554 0,09212786 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01925254 0,09538287 ! protein maturation GO:0051604 51 51 1,000 0,01925254 0,09512715 ! RNA localization GO:0006403 52 52 1,000 0,01997082 0,09841237 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,01997082 0,09814993 ! response to light stimulus GO:0009416 53 52 1,000 0,01997082 0,0978889 ! response to hypoxia GO:0001666 53 53 1,000 0,02070029 0,10119533 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,02070029 0,10092762 ! regulation of T cell activation GO:0050863 53 53 1,000 0,02070029 0,10066132 ! rRNA transcription GO:0009303 5 5 0,000 0,02090468 0,10138771 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02090468 0,1011216 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02090468 0,10085689 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02090468 0,10059355 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02090468 0,10033159 ! reproductive cellular process GO:0048610 5 5 0,000 0,02090468 0,10007099 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02090468 0,09981174 ! prostate gland development GO:0030850 5 5 0,000 0,02090468 0,09955383 ! metencephalon development GO:0022037 5 5 0,000 0,02090468 0,09929725 ! water transport GO:0006833 5 5 0,000 0,02090468 0,09904198 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02090468 0,09878803 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02090468 0,09853537 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02090468 0,09828401 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02090468 0,09803392 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02090468 0,0977851 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02090468 0,09753755 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02090468 0,09729124 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02090468 0,09704617 ! filopodium assembly GO:0046847 7 5 0,000 0,02090468 0,09680234 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02090468 0,09655973 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02090468 0,09631833 ! GTP metabolic process GO:0046039 5 5 0,000 0,02090468 0,09607813 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02090468 0,09583913 ! mRNA stabilization GO:0048255 5 5 0,000 0,02090468 0,09560132 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02090468 0,09536468 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02090468 0,09512921 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02090468 0,0948949 ! social behavior GO:0035176 5 5 0,000 0,02090468 0,09466175 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02090468 0,09442973 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02090468 0,09419885 ! memory GO:0007613 5 5 0,000 0,02090468 0,0939691 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02090468 0,09374047 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02090468 0,09351294 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02090468 0,09328652 ! response to lipid GO:0033993 5 5 0,000 0,02090468 0,09306119 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02090468 0,09283694 ! hippocampus development GO:0021766 6 5 0,000 0,02090468 0,09261378 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02090468 0,09239168 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02090468 0,09217065 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02090468 0,09195067 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02090468 0,09173174 ! heart looping GO:0001947 5 5 0,000 0,02090468 0,09151385 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02090468 0,09129699 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02090468 0,09108116 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02090468 0,09086635 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02090468 0,09065254 ! pH reduction GO:0045851 5 5 0,000 0,02090468 0,09043974 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02090468 0,09022794 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02090468 0,09001713 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02090468 0,0898073 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02090468 0,08959844 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02090468 0,08939056 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02090468 0,08918364 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02090468 0,08897767 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02090468 0,08877265 ! adrenal gland development GO:0030325 5 5 0,000 0,02090468 0,08856858 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02090468 0,08836544 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02090468 0,08816323 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02090468 0,08796194 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02090468 0,08776157 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02090468 0,08756212 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02090468 0,08736356 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02090468 0,08716591 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02090468 0,08696915 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02090468 0,08677327 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02090468 0,08657827 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02090468 0,08638415 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02090468 0,0861909 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02090468 0,08599851 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02090468 0,08580697 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02090468 0,08561629 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02090468 0,08542646 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02090468 0,08523746 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02090468 0,0850493 ! response to ATP GO:0033198 5 5 0,000 0,02090468 0,08486196 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02090468 0,08467545 ! regulation of appetite GO:0032098 5 5 0,000 0,02090468 0,08448976 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02090468 0,08430488 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02090468 0,08412081 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,02090468 0,08393754 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02090468 0,08375507 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02090468 0,08357339 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02090468 0,08339249 ! receptor clustering GO:0043113 5 5 0,000 0,02090468 0,08321238 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02090468 0,08303304 ! fear response GO:0042596 5 5 0,000 0,02090468 0,08285448 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02090468 0,08267668 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02090468 0,08249964 ! retinol metabolic process GO:0042572 5 5 0,000 0,02090468 0,08232336 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02090468 0,08214783 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02090468 0,08197305 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02090468 0,081799 ! parturition GO:0007567 5 5 0,000 0,02090468 0,0816257 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02090468 0,08145313 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02090468 0,08128129 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02090468 0,08111017 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02090468 0,08093977 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02090468 0,08077009 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02090468 0,08060111 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02090468 0,08043284 ! response to UV-B GO:0010224 5 5 0,000 0,02090468 0,08026527 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02090468 0,0800984 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02090468 0,07993222 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02090468 0,07976673 ! interaction with symbiont GO:0051702 5 5 0,000 0,02090468 0,07960192 ! cellular extravasation GO:0045123 5 5 0,000 0,02090468 0,0794378 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02090468 0,07927434 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02090468 0,07911156 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02090468 0,07894945 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02090468 0,078788 ! response to amine stimulus GO:0014075 5 5 0,000 0,02090468 0,07862721 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02090468 0,07846707 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02090468 0,07830758 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02090468 0,07814874 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02090468 0,07799055 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02090468 0,07783299 ! neuron recognition GO:0008038 5 5 0,000 0,02090468 0,07767607 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02090468 0,07751978 ! decidualization GO:0046697 5 5 0,000 0,02090468 0,07736412 ! hair follicle maturation GO:0048820 5 5 0,000 0,02090468 0,07720908 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02090468 0,07705466 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02090468 0,07690086 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02090468 0,07674767 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02090468 0,07659509 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02090468 0,07644312 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02090468 0,07629175 ! postreplication repair GO:0006301 5 5 0,000 0,02090468 0,07614097 ! cellular pigmentation GO:0033059 5 5 0,000 0,02090468 0,07599079 ! histone methylation GO:0016571 5 5 0,000 0,02090468 0,0758412 ! DNA methylation GO:0006306 5 5 0,000 0,02090468 0,0756922 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02090468 0,07554379 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02090468 0,07539595 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02090468 0,07524869 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02090468 0,07510201 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02090468 0,0749559 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02090468 0,07481035 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02090468 0,07466537 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02090468 0,07452095 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02090468 0,07437709 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02090468 0,07423378 ! sterol catabolic process GO:0016127 5 5 0,000 0,02090468 0,07409102 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02090468 0,07394881 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02090468 0,07380715 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02090468 0,07366603 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02090468 0,07352544 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02090468 0,07338539 ! zymogen activation GO:0031638 5 5 0,000 0,02090468 0,07324588 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02090468 0,07310689 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02090468 0,07296843 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02090468 0,07283049 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02090468 0,07269308 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02090468 0,07255618 ! nucleosome positioning GO:0016584 5 5 0,000 0,02090468 0,0724198 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02090468 0,07228392 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02090468 0,07214856 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02090468 0,0720137 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02090468 0,07187935 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02090468 0,0717455 ! NADPH regeneration GO:0006740 5 5 0,000 0,02090468 0,07161214 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02090468 0,07147928 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02090468 0,07134691 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02090468 0,07121503 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02090468 0,07108364 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02090468 0,07095273 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02090468 0,0708223 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02090468 0,07069235 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02090468 0,07056288 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02090468 0,07043388 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02090468 0,07030535 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02090468 0,07017729 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02090468 0,07004969 ! spleen development GO:0048536 5 5 0,000 0,02090468 0,06992256 ! male genitalia development GO:0030539 5 5 0,000 0,02090468 0,06979589 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02090468 0,06966968 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02090468 0,06954392 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02090468 0,06941861 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02090468 0,06929376 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02090468 0,06916936 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02090468 0,0690454 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02090468 0,06892188 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02090468 0,06879881 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02090468 0,06867617 ! ATP catabolic process GO:0006200 5 5 0,000 0,02090468 0,06855397 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02090468 0,0684322 ! blastocyst formation GO:0001825 5 5 0,000 0,02090468 0,06831087 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02090468 0,06818997 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02090468 0,06806949 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02090468 0,06794944 ! activation of innate immune response GO:0002218 5 5 0,000 0,02090468 0,06782981 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02090468 0,0677106 ! catecholamine transport GO:0051937 5 5 0,000 0,02090468 0,06759181 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02090468 0,06747343 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02090468 0,06735547 ! muscle adaptation GO:0043500 5 5 0,000 0,02090468 0,06723793 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02090468 0,06712079 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02090468 0,06700405 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02090468 0,06688773 ! defense response to fungus GO:0050832 5 5 0,000 0,02090468 0,0667718 ! lysogeny GO:0030069 5 5 0,000 0,02090468 0,06665628 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02090468 0,06654116 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02090468 0,06642643 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02090468 0,0663121 ! response to nicotine GO:0035094 5 5 0,000 0,02090468 0,06619816 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02090468 0,06608462 ! mitochondrion localization GO:0051646 5 5 0,000 0,02090468 0,06597146 ! nucleus localization GO:0051647 5 5 0,000 0,02090468 0,06585869 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02090468 0,0657463 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,02144085 0,0673177 ! response to oxygen levels GO:0070482 55 54 1,000 0,02144085 0,06720322 ! response to virus GO:0009615 54 54 1,000 0,02144085 0,06708912 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,02144085 0,06697541 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,0221924 0,06920574 ! reproductive developmental process GO:0003006 56 56 1,000 0,02295484 0,07146244 ! extracellular structure organization GO:0043062 56 56 1,000 0,02295484 0,07134193 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02503469 0,07767496 ! axon extension GO:0048675 7 6 0,000 0,02503469 0,07754441 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02503469 0,0774143 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,02503469 0,07728463 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,02503469 0,07715539 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02503469 0,07702659 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02503469 0,07689821 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02503469 0,07677026 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02503469 0,07664273 ! regulation of S phase GO:0033261 6 6 0,000 0,02503469 0,07651563 ! myotube differentiation GO:0014902 6 6 0,000 0,02503469 0,07638895 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02503469 0,07626269 ! bone remodeling GO:0046849 6 6 0,000 0,02503469 0,07613684 ! N-glycan processing GO:0006491 6 6 0,000 0,02503469 0,07601141 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02503469 0,07588639 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02503469 0,07576178 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02503469 0,07563758 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02503469 0,07551379 ! RNA methylation GO:0001510 6 6 0,000 0,02503469 0,0753904 ! cartilage condensation GO:0001502 7 6 0,000 0,02503469 0,07526741 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02503469 0,07514483 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02503469 0,07502264 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02503469 0,07490085 ! artery development GO:0060840 6 6 0,000 0,02503469 0,07477946 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02503469 0,07465845 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02503469 0,07453784 ! androgen metabolic process GO:0008209 6 6 0,000 0,02503469 0,07441762 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02503469 0,07429779 ! limbic system development GO:0021761 7 6 0,000 0,02503469 0,07417834 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02503469 0,07405927 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02503469 0,07394059 ! pathogenesis GO:0009405 6 6 0,000 0,02503469 0,07382228 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02503469 0,07370435 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02503469 0,0735868 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02503469 0,07346963 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02503469 0,07335282 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02503469 0,07323639 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02503469 0,07312032 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02503469 0,07300463 ! arginine metabolic process GO:0006525 6 6 0,000 0,02503469 0,0728893 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02503469 0,07277433 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02503469 0,07265972 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02503469 0,07254548 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02503469 0,07243159 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02503469 0,07231806 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02503469 0,07220489 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02503469 0,07209207 ! V(D)J recombination GO:0033151 6 6 0,000 0,02503469 0,0719796 ! focal adhesion formation GO:0048041 7 6 0,000 0,02503469 0,07186748 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02503469 0,07175572 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02503469 0,07164429 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02503469 0,07153322 ! lipid digestion GO:0044241 6 6 0,000 0,02503469 0,07142248 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02503469 0,07131209 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02503469 0,07120204 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02503469 0,07109233 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02503469 0,07098296 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02503469 0,07087392 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02503469 0,07076522 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02503469 0,07065685 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02503469 0,07054882 ! L-amino acid transport GO:0015807 6 6 0,000 0,02503469 0,07044111 ! bone mineralization GO:0030282 6 6 0,000 0,02503469 0,07033373 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02503469 0,07022667 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02503469 0,07011995 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02503469 0,07001354 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02503469 0,06990746 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02503469 0,0698017 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02503469 0,06969626 ! regulation of organ growth GO:0046620 6 6 0,000 0,02503469 0,06959114 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02503469 0,06948633 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02503469 0,06938184 ! response to dsRNA GO:0043331 6 6 0,000 0,02503469 0,06927767 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02503469 0,0691738 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02503469 0,06907025 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02503469 0,068967 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02503469 0,06886407 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02503469 0,06876144 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02503469 0,06865911 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02503469 0,0685571 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02503469 0,06845538 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02503469 0,06835396 ! erythrocyte development GO:0048821 6 6 0,000 0,02503469 0,06825285 ! renal water homeostasis GO:0003091 6 6 0,000 0,02503469 0,06815203 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02503469 0,06805151 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02503469 0,06795129 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02503469 0,06785136 ! ribosome assembly GO:0042255 6 6 0,000 0,02503469 0,06775173 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02503469 0,06765238 ! diencephalon development GO:0021536 6 6 0,000 0,02503469 0,06755333 ! fucose catabolic process GO:0019317 6 6 0,000 0,02503469 0,06745457 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02503469 0,06735609 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02503469 0,06725791 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02503469 0,06716001 ! regulation of cell division GO:0051302 6 6 0,000 0,02503469 0,06706239 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02503469 0,06696506 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02503469 0,06686801 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02503469 0,06677124 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02503469 0,06667475 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02503469 0,06657854 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02503469 0,0664826 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02503469 0,06638694 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02503469 0,06629156 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02503469 0,06619645 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02503469 0,06610161 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02503469 0,06600705 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02503469 0,06591275 ! thymus development GO:0048538 6 6 0,000 0,02503469 0,06581872 ! lymph node development GO:0048535 6 6 0,000 0,02503469 0,06572496 ! organic cation transport GO:0015695 6 6 0,000 0,02503469 0,06563147 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02503469 0,06553825 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02503469 0,06544528 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02503469 0,06535259 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02503469 0,06526015 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02503469 0,06516797 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02503469 0,06507606 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02503469 0,0649844 ! alditol metabolic process GO:0019400 6 6 0,000 0,02503469 0,064893 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02503469 0,06480186 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02503469 0,06471097 ! maternal placenta development GO:0001893 6 6 0,000 0,02503469 0,06462034 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02503469 0,06452997 ! localization within membrane GO:0051668 6 6 0,000 0,02503469 0,06443984 ! dephosphorylation GO:0016311 60 59 1,000 0,0253065 0,06504866 ! immune effector process GO:0002252 59 59 1,000 0,0253065 0,06495806 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,02775267 0,07113792 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,02775267 0,07103912 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,02775267 0,07094059 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02775267 0,07084234 ! respiratory burst GO:0045730 7 7 0,000 0,02914786 0,07430085 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02914786 0,07419822 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02914786 0,07409588 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02914786 0,07399382 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02914786 0,07389204 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02914786 0,07379054 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02914786 0,07368932 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02914786 0,07358838 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02914786 0,07348771 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02914786 0,07338731 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02914786 0,0732872 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02914786 0,07318735 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02914786 0,07308777 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02914786 0,07298847 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02914786 0,07288944 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02914786 0,07279067 ! axis specification GO:0009798 7 7 0,000 0,02914786 0,07269217 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02914786 0,07259394 ! visual behavior GO:0007632 7 7 0,000 0,02914786 0,07249597 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02914786 0,07239827 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02914786 0,07230083 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02914786 0,07220365 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02914786 0,07210673 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02914786 0,07201007 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02914786 0,07191367 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02914786 0,07181753 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02914786 0,07172165 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02914786 0,07162602 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02914786 0,07153065 ! protein targeting to ER GO:0045047 8 7 0,000 0,02914786 0,07143552 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02914786 0,07134066 ! endoderm development GO:0007492 7 7 0,000 0,02914786 0,07124604 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02914786 0,07115167 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02914786 0,07105756 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02914786 0,07096369 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02914786 0,07087007 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02914786 0,0707767 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02914786 0,07068357 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02914786 0,07059069 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02914786 0,07049805 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02914786 0,07040565 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02914786 0,0703135 ! UV protection GO:0009650 7 7 0,000 0,02914786 0,07022159 ! DNA integration GO:0015074 7 7 0,000 0,02914786 0,07012991 ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02914786 0,07003848 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02914786 0,06994728 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02914786 0,06985633 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02914786 0,0697656 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02914786 0,06967512 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02914786 0,06958486 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02914786 0,06949484 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02914786 0,06940506 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02914786 0,0693155 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02914786 0,06922618 ! axon cargo transport GO:0008088 7 7 0,000 0,02914786 0,06913708 ! eating behavior GO:0042755 7 7 0,000 0,02914786 0,06904822 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02914786 0,06895958 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02914786 0,06887117 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02914786 0,06878299 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02914786 0,06869503 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02914786 0,0686073 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02914786 0,06851979 ! induction of an organ GO:0001759 7 7 0,000 0,02914786 0,0684325 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02914786 0,06834544 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02914786 0,0682586 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02914786 0,06817197 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02914786 0,06808557 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02914786 0,06799939 ! platelet activation GO:0030168 8 7 0,000 0,02914786 0,06791342 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02914786 0,06782767 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02914786 0,06774214 ! natural killer cell activation GO:0030101 7 7 0,000 0,02914786 0,06765682 ! NADP metabolic process GO:0006739 7 7 0,000 0,02914786 0,06757172 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02914786 0,06748683 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02914786 0,06740215 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02914786 0,06731769 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02914786 0,06723343 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02914786 0,06714939 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02914786 0,06706556 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02914786 0,06698194 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02914786 0,06689852 ! cell-cell recognition GO:0009988 8 7 0,000 0,02914786 0,06681532 ! hormone catabolic process GO:0042447 7 7 0,000 0,02914786 0,06673232 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02914786 0,06664952 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02914786 0,06656693 ! oxygen transport GO:0015671 7 7 0,000 0,02914786 0,06648455 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02914786 0,06640237 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02914786 0,06632039 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02914786 0,06623861 ! regulation of axon extension GO:0030516 7 7 0,000 0,02914786 0,06615704 ! cell killing GO:0001906 7 7 0,000 0,02914786 0,06607566 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02914786 0,06599449 ! adult feeding behavior GO:0008343 7 7 0,000 0,02914786 0,06591351 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02914786 0,06583274 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02914786 0,06575216 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02914786 0,06567178 ! response to cold GO:0009409 7 7 0,000 0,02914786 0,06559159 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02943467 0,06615621 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,02943467 0,06607563 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02943467 0,06599525 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,03203262 0,07173284 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! muscle contraction GO:0006936 67 67 1,000 0,03203262 0,07164578 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,03203262 0,07155894 ! response to radiation GO:0009314 70 68 1,000 0,03291822 0,07344829 ! regulation of cell size GO:0008361 68 68 1,000 0,03291822 0,07335948 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03324429 0,07399664 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03324429 0,07390738 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03324429 0,07381834 ! positive regulation of translation GO:0045727 8 8 0,000 0,03324429 0,07372951 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03324429 0,07364089 ! superoxide anion generation GO:0042554 8 8 0,000 0,03324429 0,07355249 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03324429 0,07346429 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03324429 0,07337631 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03324429 0,07328854 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03324429 0,07320098 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03324429 0,07311363 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03324429 0,07302649 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03324429 0,07293955 ! zinc ion transport GO:0006829 8 8 0,000 0,03324429 0,07285282 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03324429 0,0727663 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03324429 0,07267998 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03324429 0,07259386 ! lipid localization GO:0010876 8 8 0,000 0,03324429 0,07250795 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03324429 0,07242225 ! response to cAMP GO:0051591 8 8 0,000 0,03324429 0,07233674 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03324429 0,07225144 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03324429 0,07216634 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03324429 0,07208144 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03324429 0,07199673 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03324429 0,07191223 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03324429 0,07182793 ! sensory perception of taste GO:0050909 8 8 0,000 0,03324429 0,07174382 ! organelle fusion GO:0048284 8 8 0,000 0,03324429 0,07165991 ! pancreas development GO:0031016 8 8 0,000 0,03324429 0,07157619 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03324429 0,07149267 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03324429 0,07140935 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03324429 0,07132622 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03324429 0,07124328 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03324429 0,07116054 ! sperm motility GO:0030317 8 8 0,000 0,03324429 0,07107798 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03324429 0,07099562 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03324429 0,07091345 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03324429 0,07083147 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03324429 0,07074968 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03324429 0,07066808 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03324429 0,07058666 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03324429 0,07050543 ! Golgi organization GO:0007030 8 8 0,000 0,03324429 0,07042439 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03324429 0,07034354 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03324429 0,07026287 ! fructose metabolic process GO:0006000 8 8 0,000 0,03324429 0,07018238 ! mannose metabolic process GO:0006013 9 8 0,000 0,03324429 0,07010208 ! NAD metabolic process GO:0019674 8 8 0,000 0,03324429 0,07002197 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03324429 0,06994203 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03324429 0,06986228 ! response to fungus GO:0009620 8 8 0,000 0,03324429 0,06978271 ! stem cell differentiation GO:0048863 8 8 0,000 0,03324429 0,06970332 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03324429 0,06962411 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03324429 0,06954509 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03324429 0,06946624 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03324429 0,06938757 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03324429 0,06930907 ! vasoconstriction GO:0042310 8 8 0,000 0,03324429 0,06923076 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03324429 0,06915262 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03324429 0,06907466 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03324429 0,06899687 ! sensory perception of pain GO:0019233 8 8 0,000 0,03324429 0,06891926 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03324429 0,06884182 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! chromatin silencing GO:0006342 8 8 0,000 0,03324429 0,06876456 ! tissue regeneration GO:0042246 8 8 0,000 0,03324429 0,06868747 ! salivary gland development GO:0007431 8 8 0,000 0,03324429 0,06861055 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03324429 0,0685338 ! T cell homeostasis GO:0043029 8 8 0,000 0,03324429 0,06845723 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03324429 0,06838083 ! water homeostasis GO:0030104 8 8 0,000 0,03324429 0,06830459 ! cofactor transport GO:0051181 8 8 0,000 0,03324429 0,06822853 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03324429 0,06815264 ! acid secretion GO:0046717 8 8 0,000 0,03324429 0,06807691 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03324429 0,06800136 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03324429 0,06792597 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03324429 0,06785074 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03324429 0,06777569 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03324429 0,0677008 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03324429 0,06762607 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03324429 0,06755151 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03324429 0,06747712 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03324429 0,06740288 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03324429 0,06732881 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03324429 0,06725491 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03324429 0,06718116 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03324429 0,06710758 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03324429 0,06703416 ! developmental induction GO:0031128 8 8 0,000 0,03324429 0,0669609 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03324429 0,0668878 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03324429 0,06681485 ! actin filament polymerization GO:0030041 9 8 0,000 0,03324429 0,06674207 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03324429 0,06666945 ! peptide hormone processing GO:0016486 8 8 0,000 0,03324429 0,06659698 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03324429 0,06652467 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03324429 0,06645252 ! response to nutrient levels GO:0031667 69 69 1,000 0,03381348 0,06751706 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,03381348 0,06744399 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,03381348 0,06737108 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0347183 0,06909917 ! growth GO:0040007 70 70 1,000 0,0347183 0,06902463 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0356326 0,07076603 ! regulation of cell activation GO:0050865 71 71 1,000 0,0356326 0,07068986 ! muscle system process GO:0003012 72 72 1,000 0,03655628 0,07244432 ! sensory organ development GO:0007423 72 72 1,000 0,03655628 0,07236651 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03655628 0,07228886 ! lactation GO:0007595 10 9 0,000 0,03732402 0,07372794 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03732402 0,073649 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03732402 0,07357023 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03732402 0,07349163 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03732402 0,0734132 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03732402 0,07333493 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,03732402 0,07325683 ! viral genome replication GO:0019079 9 9 0,000 0,03732402 0,0731789 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03732402 0,07310113 ! copper ion transport GO:0006825 9 9 0,000 0,03732402 0,07302353 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03732402 0,07294609 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03732402 0,07286882 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03732402 0,07279171 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03732402 0,07271476 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03732402 0,07263798 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03732402 0,07256136 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03732402 0,0724849 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03732402 0,0724086 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03732402 0,07233246 ! phospholipid efflux GO:0033700 9 9 0,000 0,03732402 0,07225648 ! response to alkaloid GO:0043279 10 9 0,000 0,03732402 0,07218066 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03732402 0,072105 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03732402 0,07202949 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03732402 0,07195415 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03732402 0,07187896 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03732402 0,07180393 ! response to ethanol GO:0045471 9 9 0,000 0,03732402 0,07172906 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03732402 0,07165434 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03732402 0,07157978 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03732402 0,07150537 ! methionine metabolic process GO:0006555 9 9 0,000 0,03732402 0,07143112 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03732402 0,07135702 ! cerebral cortex development GO:0021987 9 9 0,000 0,03732402 0,07128307 ! response to osmotic stress GO:0006970 9 9 0,000 0,03732402 0,07120928 ! pigmentation during development GO:0048066 9 9 0,000 0,03732402 0,07113564 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03732402 0,07106216 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03732402 0,07098882 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03732402 0,07091564 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03732402 0,0708426 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03732402 0,07076972 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03732402 0,07069699 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03732402 0,0706244 ! L-glutamate transport GO:0015813 9 9 0,000 0,03732402 0,07055197 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03732402 0,07047968 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03732402 0,07040754 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03732402 0,07033555 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03732402 0,0702637 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03732402 0,07019201 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03732402 0,07012046 ! DNA replication initiation GO:0006270 9 9 0,000 0,03732402 0,07004905 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03732402 0,06997779 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03732402 0,06990667 ! histone acetylation GO:0016573 9 9 0,000 0,03732402 0,0698357 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03732402 0,06976487 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03732402 0,06969419 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03732402 0,06962365 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03732402 0,06955325 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03732402 0,069483 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03732402 0,06941288 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03732402 0,06934291 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03732402 0,06927308 ! collagen catabolic process GO:0030574 9 9 0,000 0,03732402 0,06920339 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03732402 0,06913384 ! purine base metabolic process GO:0006144 9 9 0,000 0,03732402 0,06906442 ! gas transport GO:0015669 9 9 0,000 0,03732402 0,06899515 ! cholesterol efflux GO:0033344 9 9 0,000 0,03732402 0,06892602 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03732402 0,06885702 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03732402 0,06878817 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03732402 0,06871945 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03732402 0,06865086 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03732402 0,06858242 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03732402 0,06851411 ! response to oxidative stress GO:0006979 76 75 1,000 0,03938273 0,07222127 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,04034306 0,0739088 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,04034306 0,07383541 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04138713 0,0756711 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04138713 0,07559611 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04138713 0,07552126 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04138713 0,07544656 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04138713 0,07537201 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04138713 0,0752976 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04138713 0,07522334 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04138713 0,07514923 GO:0045767|regulation of anti-apoptosis, ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04138713 0,07507527 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04138713 0,07500145 ! hormone secretion GO:0046879 10 10 0,000 0,04138713 0,07492777 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04138713 0,07485424 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04138713 0,07478085 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,04138713 0,07470761 ! cAMP metabolic process GO:0046058 10 10 0,000 0,04138713 0,07463451 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04138713 0,07456156 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04138713 0,07448874 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04138713 0,07441607 ! glial cell development GO:0021782 10 10 0,000 0,04138713 0,07434354 ! phototransduction GO:0007602 11 10 0,000 0,04138713 0,07427115 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,04138713 0,0741989 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04138713 0,07412679 ! fat cell differentiation GO:0045444 10 10 0,000 0,04138713 0,07405483 ! myoblast differentiation GO:0045445 10 10 0,000 0,04138713 0,073983 ! centrosome cycle GO:0007098 10 10 0,000 0,04138713 0,07391131 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04138713 0,07383976 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04138713 0,07376835 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04138713 0,07369707 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04138713 0,07362594 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04138713 0,07355494 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04138713 0,07348408 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04138713 0,07341335 ! plasma membrane organization GO:0007009 10 10 0,000 0,04138713 0,07334276 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04138713 0,07327231 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04138713 0,07320199 ! lysosomal transport GO:0007041 10 10 0,000 0,04138713 0,0731318 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04138713 0,07306175 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04138713 0,07299184 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,04138713 0,07292206 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,04138713 0,07285241 ! exocrine system development GO:0035272 10 10 0,000 0,04138713 0,07278289 ! embryo implantation GO:0007566 11 10 0,000 0,04138713 0,07271351 ! regulation of protein binding GO:0043393 11 10 0,000 0,04138713 0,07264426 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04138713 0,07257514 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04138713 0,07250615 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04138713 0,07243729 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04138713 0,07236857 ! protein export from nucleus GO:0006611 10 10 0,000 0,04138713 0,07229997 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04138713 0,07223151 ! cytolysis GO:0019835 10 10 0,000 0,04138713 0,07216317 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04138713 0,07209496 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04138713 0,07202689 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04138713 0,07195894 ! histone deacetylation GO:0016575 10 10 0,000 0,04138713 0,07189111 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04138713 0,07182342 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04138713 0,07175585 ! gland morphogenesis GO:0022612 10 10 0,000 0,04138713 0,07168841 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04138713 0,0716211 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04138713 0,07155391 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04138713 0,07148685 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04138713 0,07141992 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,04138713 0,07135311 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04138713 0,07128642 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04138713 0,07121986 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04138713 0,07115342 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04138713 0,07108711 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04138713 0,07102092 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04138713 0,07095486 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04138713 0,07088891 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04138713 0,07082309 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04138713 0,07075739 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04138713 0,07069182 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04138713 0,07062636 ! protein stabilization GO:0050821 10 10 0,000 0,04138713 0,07056103 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,04229045 0,07203448 ! neuron projection development GO:0031175 85 80 1,000 0,04427293 0,07534166 ! tube development GO:0035295 83 81 1,000 0,04527711 0,07697944 ! lymphocyte activation GO:0046649 82 81 1,000 0,04527711 0,0769085 ! protein secretion GO:0009306 11 11 0,000 0,04543367 0,07710337 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04543367 0,07703243 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04543367 0,07696163 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04543367 0,07689096 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04543367 0,07682042 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04543367 0,07675001 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04543367 0,07667972 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04543367 0,07660957 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04543367 0,07653954 ! skin development GO:0043588 11 11 0,000 0,04543367 0,07646964 ! signal complex assembly GO:0007172 11 11 0,000 0,04543367 0,07639987 ! microtubule-based transport GO:0010970 11 11 0,000 0,04543367 0,07633022 ! endothelial cell migration GO:0043542 11 11 0,000 0,04543367 0,07626071 ! peroxisomal transport GO:0043574 11 11 0,000 0,04543367 0,07619132 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04543367 0,07612205 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04543367 0,07605291 ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04543367 0,0759839 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04543367 0,07591501 ! T cell proliferation GO:0042098 11 11 0,000 0,04543367 0,07584625 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04543367 0,07577761 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04543367 0,07570909 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04543367 0,0756407 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04543367 0,07557243 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04543367 0,07550429 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04543367 0,07543627 ! digestive system process GO:0022600 11 11 0,000 0,04543367 0,07536837 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04543367 0,07530059 ! fucose metabolic process GO:0006004 11 11 0,000 0,04543367 0,07523293 ! membrane budding GO:0006900 11 11 0,000 0,04543367 0,0751654 ! monoamine transport GO:0015844 11 11 0,000 0,04543367 0,07509799 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04543367 0,0750307 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04543367 0,07496352 ! body fluid secretion GO:0007589 11 11 0,000 0,04543367 0,07489647 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04543367 0,07482954 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04543367 0,07476273 ! membrane depolarization GO:0051899 11 11 0,000 0,04543367 0,07469604 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04543367 0,07462946 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04543367 0,07456301 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,04543367 0,07449667 ! oogenesis GO:0048477 11 11 0,000 0,04543367 0,07443045 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04543367 0,07436435 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04543367 0,07429836 ! vitamin transport GO:0051180 11 11 0,000 0,04543367 0,0742325 ! muscle maintenance GO:0046716 12 11 0,000 0,04543367 0,07416675 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04543367 0,07410111 ! steroid catabolic process GO:0006706 11 11 0,000 0,04543367 0,07403559 ! endocrine process GO:0050886 11 11 0,000 0,04543367 0,07397019 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04543367 0,0739049 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04543367 0,07383973 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04543367 0,07377468 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,04937814 0,08010908 ! translational initiation GO:0006413 12 12 0,000 0,04946372 0,08017734 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04946372 0,08010689 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04946372 0,08003656 ! initiation of viral infection GO:0019059 12 12 0,000 0,04946372 0,07996635 ! iron ion transport GO:0006826 13 12 0,000 0,04946372 0,07989627 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04946372 0,07982631 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04946372 0,07975647 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04946372 0,07968675 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04946372 0,07961715 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04946372 0,07954768 ! collagen metabolic process GO:0032963 12 12 0,000 0,04946372 0,07947833 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04946372 0,0794091 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04946372 0,07933998 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04946372 0,07927099 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04946372 0,07920212 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04946372 0,07913337 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04946372 0,07906474 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04946372 0,07899622 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04946372 0,07892783 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,04946372 0,07885955 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04946372 0,07879139 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04946372 0,07872335 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04946372 0,07865543 GO:0006505|GPI anchor metabolic process, ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04946372 0,07858762 ! vacuolar transport GO:0007034 12 12 0,000 0,04946372 0,07851993 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04946372 0,07845236 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04946372 0,0783849 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04946372 0,07831756 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04946372 0,07825034 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,04946372 0,07818323 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04946372 0,07811623 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04946372 0,07804935 ! renal system process GO:0003014 12 12 0,000 0,04946372 0,07798258 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04946372 0,07791593 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04946372 0,07784939 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04946372 0,07778297 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04946372 0,07771666 ! pallium development GO:0021543 13 12 0,000 0,04946372 0,07765046 ! cell fate determination GO:0001709 12 12 0,000 0,04946372 0,07758438 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04946372 0,0775184 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04946372 0,07745254 ! somitogenesis GO:0001756 13 12 0,000 0,04946372 0,07738679 ! G1 phase GO:0051318 13 12 0,000 0,04946372 0,07732115 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04946372 0,07725563 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04946372 0,07719021 ! detection of light stimulus GO:0009583 13 12 0,000 0,04946372 0,07712491 ! synaptogenesis GO:0007416 12 12 0,000 0,04946372 0,07705971 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04946372 0,07699463 ! hormone transport GO:0009914 12 12 0,000 0,04946372 0,07692965 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04946372 0,07686479 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04946372 0,07680003 ! spermatid differentiation GO:0048515 13 12 0,000 0,04946372 0,07673539 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04946372 0,07667085 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04946372 0,07660642 ! neural tube closure GO:0001843 13 12 0,000 0,04946372 0,0765421 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04946372 0,07647789 ! negative regulation of translation GO:0017148 12 12 0,000 0,04946372 0,07641378 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04946372 0,07634978 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,05042406 0,07776698 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,05347734 0,08240698 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,05347734 0,08233813 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,05347734 0,0822694 ! phenol metabolic process GO:0018958 13 13 0,000 0,05347734 0,08220079 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,05347734 0,08213229 ! gluconeogenesis GO:0006094 13 13 0,000 0,05347734 0,0820639 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,05347734 0,08199563 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,05347734 0,08192747 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,05347734 0,08185942 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,05347734 0,08179149 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,05347734 0,08172367 ! regeneration GO:0031099 13 13 0,000 0,05347734 0,08165596 ! keratinization GO:0031424 13 13 0,000 0,05347734 0,08158837 ! post-embryonic development GO:0009791 14 13 0,000 0,05347734 0,08152088 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,05347734 0,08145351 ! patterning of blood vessels GO:0001569 13 13 0,000 0,05347734 0,08138625 ! vasculogenesis GO:0001570 13 13 0,000 0,05347734 0,0813191 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,05347734 0,08125206 ! regulation of innate immune response GO:0045088 13 13 0,000 0,05347734 0,08118513 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,05347734 0,08111831 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,05347734 0,0810516 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,05347734 0,080985 ! autophagy GO:0006914 13 13 0,000 0,05347734 0,08091851 ! receptor metabolic process GO:0043112 14 13 0,000 0,05347734 0,08085213 ! actin filament bundle formation GO:0051017 13 13 0,000 0,05347734 0,08078586 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,05347734 0,08071969 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,05347734 0,08065364 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,05347734 0,08058769 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,05347734 0,08052185 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,05347734 0,08045612 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,05347734 0,08039049 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,05347734 0,08032498 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,05347734 0,08025956 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,05347734 0,08019426 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,05347734 0,08012906 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,05347734 0,08006397 ! vasodilation GO:0042311 14 13 0,000 0,05347734 0,07999898 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,05347734 0,0799341 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,05347734 0,07986932 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,05347734 0,07980465 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,05347734 0,07974009 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,05347734 0,07967562 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,05347734 0,07961126 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,05347734 0,07954701 ! immunoglobulin production GO:0002377 13 13 0,000 0,05347734 0,07948286 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,05347734 0,07941881 ! cell-cell junction organization GO:0045216 13 13 0,000 0,05347734 0,07935487 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,05347734 0,07929103 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,05347734 0,07922729 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,05347734 0,07916365 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,05347734 0,07910012 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,05347734 0,07903668 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,05347734 0,07897335 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,05347734 0,07891012 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,05347734 0,078847 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,05347734 0,07878397 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,05347734 0,07872104 ! blastocyst development GO:0001824 13 13 0,000 0,05347734 0,07865822 ! telomere organization GO:0032200 13 13 0,000 0,05347734 0,07859549 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,05347734 0,07853286 ! regulation of amine transport GO:0051952 13 13 0,000 0,05347734 0,07847034 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,05347734 0,07840791 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,05468791 0,08011909 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,05577351 0,08164463 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,0574746 0,08406801 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,0574746 0,08400134 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,0574746 0,08393478 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,0574746 0,08386832 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,0574746 0,08380197 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,0574746 0,08373572 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,0574746 0,08366958 ! protein amino acid acylation GO:0043543 14 14 0,000 0,0574746 0,08360354 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,0574746 0,08353761 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,0574746 0,08347178 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,0574746 0,08340605 ! vesicle docking GO:0048278 14 14 0,000 0,0574746 0,08334043 ! superoxide metabolic process GO:0006801 15 14 0,000 0,0574746 0,08327491 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,0574746 0,0832095 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,0574746 0,08314418 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,0574746 0,08307897 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,0574746 0,08301386 ! hair cycle GO:0042633 14 14 0,000 0,0574746 0,08294886 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,0574746 0,08288395 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,0574746 0,08281915 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,0574746 0,08275444 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,0574746 0,08268984 ! lysosome organization GO:0007040 14 14 0,000 0,0574746 0,08262534 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,0574746 0,08256094 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,0574746 0,08249664 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,0574746 0,08243244 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,0574746 0,08236834 ! primary neural tube formation GO:0014020 15 14 0,000 0,0574746 0,08230434 ! peptide cross-linking GO:0018149 14 14 0,000 0,0574746 0,08224044 ! regulation of behavior GO:0050795 14 14 0,000 0,0574746 0,08217664 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,0574746 0,08211294 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,0574746 0,08204933 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,0574746 0,08198583 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,0574746 0,08192242 ! DNA modification GO:0006304 14 14 0,000 0,0574746 0,08185911 ! collagen fibril organization GO:0030199 14 14 0,000 0,0574746 0,0817959 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,0574746 0,08173278 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,0574746 0,08166977 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,0574746 0,08160685 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,0574746 0,08154402 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,0574746 0,0814813 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,0574746 0,08141867 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,0574746 0,08135614 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,0574746 0,0812937 ! regulation of response to stress GO:0080134 97 94 1,000 0,05907619 0,08349496 ! regulation of cell growth GO:0001558 97 96 1,000 0,06131542 0,08659334 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06145556 0,0867248 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06145556 0,08665845 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06145556 0,08659219 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,06145556 0,08652604 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06145556 0,08645999 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06145556 0,08639404 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06145556 0,08632819 ! response to vitamin GO:0033273 15 15 0,000 0,06145556 0,08626244 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06145556 0,08619679 ! ovarian follicle development GO:0001541 15 15 0,000 0,06145556 0,08613125 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06145556 0,0860658 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06145556 0,08600045 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,06145556 0,0859352 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06145556 0,08587004 ! heme metabolic process GO:0042168 15 15 0,000 0,06145556 0,08580499 ! chromosome condensation GO:0030261 15 15 0,000 0,06145556 0,08574004 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06145556 0,08567518 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06145556 0,08561042 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06145556 0,08554576 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,06145556 0,0854812 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06145556 0,08541673 ! phospholipid transport GO:0015914 15 15 0,000 0,06145556 0,08535236 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,06145556 0,08528809 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06145556 0,08522392 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06145556 0,08515984 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06145556 0,08509586 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,06145556 0,08503197 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06145556 0,08496818 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06145556 0,08490449 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,06145556 0,08484089 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06145556 0,08477739 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06145556 0,08471398 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,06358387 0,08758226 ! blood circulation GO:0008015 99 98 1,000 0,06358387 0,08751685 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 1,000 0,06472886 0,08902633 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06542027 0,08991019 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06542027 0,08984319 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06542027 0,08977629 ! learning GO:0007612 16 16 0,000 0,06542027 0,0897095 ! circadian rhythm GO:0007623 16 16 0,000 0,06542027 0,0896428 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06542027 0,0895762 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06542027 0,0895097 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,06542027 0,0894433 ! vesicle targeting GO:0006903 17 16 0,000 0,06542027 0,08937699 ! segmentation GO:0035282 17 16 0,000 0,06542027 0,08931079 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06542027 0,08924468 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06542027 0,08917867 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06542027 0,08911276 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06542027 0,08904694 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06542027 0,08898123 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06542027 0,08891561 ! pentose metabolic process GO:0019321 16 16 0,000 0,06542027 0,08885008 ! fatty acid transport GO:0015908 16 16 0,000 0,06542027 0,08878466 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06542027 0,08871933 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06542027 0,08865409 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06542027 0,08858895 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06542027 0,08852391 ! polyol metabolic process GO:0019751 16 16 0,000 0,06542027 0,08845896 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06542027 0,08839411 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06542027 0,08832935 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06542027 0,08826469 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06542027 0,08820012 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06542027 0,08813565 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06542027 0,08807127 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06542027 0,08800698 ! regulation of coagulation GO:0050818 17 16 0,000 0,06542027 0,08794279 ! response to hormone stimulus GO:0009725 102 100 1,000 0,06588093 0,08849749 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,06588093 0,08843303 ! response to other organism GO:0051707 101 100 1,000 0,06588093 0,08836867 ! hemopoiesis GO:0030097 104 100 1,000 0,06588093 0,0883044 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06936882 0,09291187 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,06936882 0,09284439 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06936882 0,09277702 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06936882 0,09270974 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06936882 0,09264256 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06936882 0,09257548 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06936882 0,09250849 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06936882 0,0924416 ! sensory perception of smell GO:0007608 17 17 0,000 0,06936882 0,09237481 ! glucose transport GO:0015758 17 17 0,000 0,06936882 0,09230811 ! cell junction assembly GO:0034329 18 17 0,000 0,06936882 0,09224151 ! tissue remodeling GO:0048771 17 17 0,000 0,06936882 0,092175 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06936882 0,0921086 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06936882 0,09204228 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06936882 0,09197607 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06936882 0,09190994 ! neural crest cell development GO:0014032 19 17 0,000 0,06936882 0,09184392 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06936882 0,09177798 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06936882 0,09171215 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06936882 0,0916464 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,06936882 0,09158075 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06936882 0,0915152 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06936882 0,09144974 ! pigmentation GO:0043473 17 17 0,000 0,06936882 0,09138437 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06936882 0,09131909 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06936882 0,09125391 ! liver development GO:0001889 17 17 0,000 0,06936882 0,09118882 ! gene silencing GO:0016458 17 17 0,000 0,06936882 0,09112383 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07330125 0,09622095 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,07330125 0,09615246 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07330125 0,09608408 ! meiosis I GO:0007127 18 18 0,000 0,07330125 0,09601579 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,07330125 0,09594759 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07330125 0,0958795 ! membrane docking GO:0022406 18 18 0,000 0,07330125 0,0958115 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,07330125 0,09574359 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07330125 0,09567579 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07330125 0,09560808 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07330125 0,09554046 ! hexose transport GO:0008645 18 18 0,000 0,07330125 0,09547294 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07330125 0,09540552 GO:0055092|sterol homeostasis, ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,07330125 0,09533819 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,07330125 0,09527095 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07330125 0,09520381 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,07330125 0,09513677 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07330125 0,09506982 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07330125 0,09500296 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,07330125 0,0949362 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,07330125 0,09486953 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07330125 0,09480295 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07721764 0,09979812 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07721764 0,09972818 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07721764 0,09965834 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07721764 0,0995886 ! feeding behavior GO:0007631 19 19 0,000 0,07721764 0,09951896 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07721764 0,09944942 ! peroxisome organization GO:0007031 19 19 0,000 0,07721764 0,09937997 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07721764 0,09931062 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07721764 0,09924136 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07721764 0,09917221 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07721764 0,09910314 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07721764 0,09903418 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07721764 0,09896531 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07721764 0,09889654 ! regulation of protein stability GO:0031647 19 19 0,000 0,07721764 0,09882786 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07721764 0,09875928 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07721764 0,09869079 ! regulation of cell shape GO:0008360 21 19 0,000 0,07721764 0,09862239 ! placenta development GO:0001890 19 19 0,000 0,07721764 0,0985541 ! response to heat GO:0009408 19 19 0,000 0,07721764 0,09848589 ! vesicle localization GO:0051648 20 19 0,000 0,07721764 0,09841778 ! regulation of muscle development GO:0048634 21 20 0,000 0,08111805 0,1033176 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,08111805 0,10324625 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,08111805 0,10317499 ! negative regulation of binding GO:0051100 21 20 0,000 0,08111805 0,10310384 ! organic ether metabolic process GO:0018904 20 20 0,000 0,08111805 0,10303278 GO:0006662|glycerol ether metabolic process, ! phagocytosis GO:0006909 21 20 0,000 0,08111805 0,10296182 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08111805 0,10289096 ! protein targeting to membrane GO:0006612 22 20 0,000 0,08111805 0,1028202 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,08111805 0,10274953 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08111805 0,10267896 ! lipid oxidation GO:0034440 20 20 0,000 0,08111805 0,10260849 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,08111805 0,10253811 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08111805 0,10246783 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08111805 0,10239765 ! RNA modification GO:0009451 20 20 0,000 0,08111805 0,10232756 ! single fertilization GO:0007338 21 20 0,000 0,08111805 0,10225757 ! regulation of B cell activation GO:0050864 20 20 0,000 0,08111805 0,10218767 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,08500254 0,10700797 ! mRNA catabolic process GO:0006402 21 21 0,000 0,08500254 0,10693493 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,08500254 0,10686199 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,08500254 0,10678914 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,08500254 0,1067164 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,08500254 0,10664375 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,08500254 0,10657121 ! ear morphogenesis GO:0042471 21 21 0,000 0,08500254 0,10649876 ! organic anion transport GO:0015711 21 21 0,000 0,08500254 0,10642641 ! cholesterol transport GO:0030301 21 21 0,000 0,08500254 0,10635416 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,08500254 0,106282 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,08500254 0,10620995 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,08500254 0,10613799 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,08500254 0,10606613 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,08500254 0,10599437 ! regulation of proteolysis GO:0030162 21 21 0,000 0,08500254 0,1059227 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,08500254 0,10585113 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,08887116 0,11059389 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,08887116 0,11051927 ! sister chromatid segregation GO:0000819 22 22 0,000 0,08887116 0,11044474 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,08887116 0,11037032 ! regulation of ion transport GO:0043269 22 22 0,000 0,08887116 0,110296 ! cell junction organization GO:0034330 23 22 0,000 0,08887116 0,11022177 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,08887116 0,11014765 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,08887116 0,11007363 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,08887116 0,1099997 ! ovulation cycle process GO:0022602 22 22 0,000 0,08887116 0,10992588 ! spindle organization GO:0007051 22 22 0,000 0,08887116 0,10985215 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,08887116 0,10977852 ! cell chemotaxis GO:0060326 23 22 0,000 0,08887116 0,10970499 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,08887116 0,10963156 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,08887116 0,10955823 ! male sex differentiation GO:0046661 22 22 0,000 0,08887116 0,109485 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,08887116 0,10941186 ! biopolymer methylation GO:0043414 22 22 0,000 0,08887116 0,10933882 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,08887116 0,10926588 ! detection of external stimulus GO:0009581 23 22 0,000 0,08887116 0,10919304 ! neuron migration GO:0001764 22 22 0,000 0,08887116 0,10912029 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,08887116 0,10904764 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,08887116 0,10897509 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,08887116 0,10890263 ! aerobic respiration GO:0009060 22 22 0,000 0,08887116 0,10883027 ! cytokine production GO:0001816 22 22 0,000 0,08887116 0,10875801 ! cytokinesis GO:0000910 23 22 0,000 0,08887116 0,10868584 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,08887116 0,10861376 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,092724 0,1132474 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,092724 0,1131724 ! viral infectious cycle GO:0019058 23 23 0,000 0,092724 0,1130975 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,092724 0,1130227 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,092724 0,112948 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,092724 0,1128734 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,092724 0,1127989 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,092724 0,11272449 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,092724 0,11265018 ! endocrine system development GO:0035270 23 23 0,000 0,092724 0,11257597 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,092724 0,11250186 ! female gonad development GO:0008585 23 23 0,000 0,092724 0,11242785 ! lipid homeostasis GO:0055088 23 23 0,000 0,092724 0,11235393 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,092724 0,11228011 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,092724 0,11220639 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,092724 0,11213276 ! cell projection assembly GO:0030031 25 23 0,000 0,092724 0,11205923 ! gliogenesis GO:0042063 24 24 0,000 0,0965611 0,11661999 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,0965611 0,11654362 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,0965611 0,11646735 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,0965611 0,11639118 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,0965611 0,1163151 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,0965611 0,11623913 ! ovulation cycle GO:0042698 24 24 0,000 0,0965611 0,11616326 ! fertilization GO:0009566 25 24 0,000 0,0965611 0,11608748 ! maintenance of protein location GO:0045185 25 24 0,000 0,0965611 0,1160118 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,0965611 0,11593623 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,10038253 0,12044597 ! negative regulation of secretion GO:0051048 26 25 0,000 0,10038253 0,1203676 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10038253 0,12028934 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10038253 0,12021118 ! endosome transport GO:0016197 25 25 0,000 0,10038253 0,12013312 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10038253 0,12005516 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,10038253 0,1199773 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10038253 0,11989955 ! excretion GO:0007588 25 25 0,000 0,10038253 0,11982189 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,10038253 0,11974434 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,10038253 0,11966688 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10038253 0,11958953 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,10038253 0,11951228 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10038253 0,11943512 ! positive regulation of binding GO:0051099 27 26 0,000 0,10418835 0,12388331 ! positive regulation of defense response GO:0031349 26 26 0,000 0,10418835 0,12380344 ! glycolysis GO:0006096 26 26 0,000 0,10418835 0,12372367 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,10418835 0,123644 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,10418835 0,12356444 ! cellular defense response GO:0006968 26 26 0,000 0,10418835 0,12348497 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,10418835 0,12340561 ! regulation of protein secretion GO:0050708 26 26 0,000 0,10418835 0,12332635 ! germ cell development GO:0007281 27 26 0,000 0,10418835 0,1232472 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,10418835 0,12316814 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,10418835 0,12308919 ! maintenance of location in cell GO:0051651 27 26 0,000 0,10418835 0,12301034 ! chloride transport GO:0006821 27 27 0,000 0,10797863 0,12740372 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,10797863 0,12732221 ! learning or memory GO:0007611 28 27 0,000 0,10797863 0,1272408 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,10797863 0,12715949 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,10797863 0,12707829 ! peptide metabolic process GO:0006518 29 27 0,000 0,10797863 0,1269972 ! inner ear development GO:0048839 27 27 0,000 0,10797863 0,1269162 ! defense response to bacterium GO:0042742 27 27 0,000 0,10797863 0,12683531 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,10797863 0,12675453 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,10797863 0,12667384 ! cell growth GO:0016049 27 27 0,000 0,10797863 0,12659326 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11175341 0,1309355 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11175341 0,13085231 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,11175341 0,13076923 ! carbohydrate transport GO:0008643 28 28 0,000 0,11175341 0,13068626 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11175341 0,13060339 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11175341 0,13052062 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,11175341 0,13043796 ! histone modification GO:0016570 28 28 0,000 0,11175341 0,13035541 ! cartilage development GO:0051216 29 28 0,000 0,11175341 0,13027295 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,11551278 0,13457019 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,11551278 0,13448518 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,11551278 0,13440028 ! leukocyte migration GO:0050900 30 29 0,000 0,11551278 0,13431549 ! antigen processing and presentation GO:0019882 29 29 0,000 0,11551278 0,1342308 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,11551278 0,13414622 ! tRNA processing GO:0008033 29 29 0,000 0,11551278 0,13406174 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,11551278 0,13397737 ! covalent chromatin modification GO:0016569 29 29 0,000 0,11551278 0,13389311 ! adult behavior GO:0030534 30 29 0,000 0,11551278 0,13380895 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,11551278 0,1337249 ! transition metal ion transport GO:0000041 31 30 0,000 0,11925677 0,13797253 ! RNA catabolic process GO:0006401 30 30 0,000 0,11925677 0,13788597 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,11925677 0,13779952 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,11925677 0,13771318 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,11925677 0,13762695 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,11925677 0,13754082 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,11925677 0,13745481 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,11925677 0,1373689 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,11925677 0,13728309 ! response to temperature stimulus GO:0009266 30 30 0,000 0,11925677 0,1371974 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,11925677 0,13711181 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,11925677 0,13702633 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,11925677 0,13694096 ! vesicle organization GO:0016050 30 30 0,000 0,11925677 0,13685569 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,11925677 0,13677053 ! establishment of organelle localization GO:0051656 31 30 0,000 0,11925677 0,13668547 ! regulation of translational initiation GO:0006446 31 31 0,000 0,12298547 0,14087148 ! membrane fusion GO:0006944 31 31 0,000 0,12298547 0,14078399 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,12298547 0,1406966 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,12298547 0,14060932 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,12298547 0,14052214 ! ion transmembrane transport GO:0034220 31 31 0,000 0,12298547 0,14043508 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,12298547 0,14034812 ! digestion GO:0007586 31 31 0,000 0,12298547 0,14026127 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,12298547 0,14017453 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,12298547 0,1400879 ! extracellular matrix organization GO:0030198 31 31 0,000 0,12298547 0,14000137 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,12298547 0,13991495 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,12298547 0,13982864 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,12298547 0,13974243 ! cell redox homeostasis GO:0045454 32 32 0,000 0,12669892 0,14387314 ! glucose catabolic process GO:0006007 32 32 0,000 0,12669892 0,14378455 ! lipid modification GO:0030258 32 32 0,000 0,12669892 0,14369607 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,12669892 0,14360769 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,12669892 0,14351943 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,12669892 0,14343127 ! nuclear export GO:0051168 32 32 0,000 0,12669892 0,14334322 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,12669892 0,14325528 ! maintenance of location GO:0051235 33 32 0,000 0,12669892 0,14316745 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,13039719 0,14725614 ! amino acid transport GO:0006865 33 33 0,000 0,13039719 0,14716596 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,13039719 0,14707589 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,13039719 0,14698594 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,13039719 0,1468961 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,13039719 0,14680636 ! regulation of actin filament length GO:0030832 34 34 0,000 0,13408033 0,15086083 ! ear development GO:0043583 34 34 0,000 0,13408033 0,15076879 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,13408033 0,15067686 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,13408033 0,15058504 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,13408033 0,15049333 ! secondary metabolic process GO:0019748 34 34 0,000 0,13408033 0,15040173 ! detection of stimulus GO:0051606 36 34 0,000 0,13408033 0,15031025 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,13774841 0,15432846 ! regulation of cellular component size GO:0032535 35 35 0,000 0,13774841 0,1542347 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,13774841 0,15414105 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,13774841 0,15404752 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,13774841 0,1539541 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,13774841 0,1538608 ! inorganic anion transport GO:0015698 35 35 0,000 0,13774841 0,1537676 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,13774841 0,15367453 ! regulation of immune effector process GO:0002697 35 35 0,000 0,13774841 0,15358156 ! hydrogen transport GO:0006818 36 36 0,000 0,14140148 0,15755921 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,14140148 0,15746401 ! regulation of mitosis GO:0007088 37 36 0,000 0,14140148 0,15736892 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,14140148 0,15727395 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,14140148 0,15717909 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,14140148 0,15708435 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,14140148 0,15698972 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,14140148 0,1568952 ! gonad development GO:0008406 36 36 0,000 0,14140148 0,1568008 ! regulation of lipase activity GO:0060191 36 36 0,000 0,14140148 0,15670651 ! activation of immune response GO:0002253 36 36 0,000 0,14140148 0,15661234 ! coagulation GO:0050817 39 36 0,000 0,14140148 0,15651828 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,14503961 0,16044898 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,14503961 0,16035273 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,14503961 0,1602566 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,14503961 0,16016058 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,14503961 0,16006467 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,14503961 0,15996888 ! adaptive immune response GO:0002250 37 37 0,000 0,14503961 0,15987321 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,14866285 0,16376906 ! neurotransmitter transport GO:0006836 40 38 0,000 0,14866285 0,16367123 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,14866285 0,16357352 ! exocytosis GO:0006887 40 38 0,000 0,14866285 0,16347592 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,14866285 0,16337844 ! hexose catabolic process GO:0019320 38 38 0,000 0,14866285 0,16328107 ! RNA elongation GO:0006354 38 38 0,000 0,14866285 0,16318382 ! meiotic cell cycle GO:0051321 38 38 0,000 0,14866285 0,16308669 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,14866285 0,16298967 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,15227127 0,16684658 ! hemostasis GO:0007599 42 39 0,000 0,15227127 0,16674745 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,15227127 0,16664843 ! response to unfolded protein GO:0006986 39 39 0,000 0,15227127 0,16654953 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,15227127 0,16645074 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,15227127 0,16635207 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,15227127 0,16625353 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,15227127 0,16615509 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,15227127 0,16605678 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,15227127 0,16595858 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,15586492 0,16977485 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,15586492 0,16967457 ! organelle localization GO:0051640 41 40 0,000 0,15586492 0,1695744 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,15944385 0,17336579 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,15944385 0,17326357 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,15944385 0,17316147 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,15944385 0,17305949 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,15944385 0,17295763 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,15944385 0,17285589 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,15944385 0,17275427 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,16300813 0,17651233 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,16300813 0,17640869 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,16300813 0,17630516 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,16300813 0,17620175 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,16300813 0,17609847 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,16300813 0,17599531 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,16300813 0,17589227 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,16300813 0,17578935 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,16300813 0,17568654 ! reproductive structure development GO:0048608 43 43 0,000 0,16655782 0,1794074 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,16655782 0,17930261 ! alcohol catabolic process GO:0046164 43 43 0,000 0,16655782 0,17919794 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,16655782 0,17909339 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,16655782 0,17898896 ! humoral immune response GO:0006959 44 44 0,000 0,17009297 0,18268144 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,17009297 0,18257504 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,17009297 0,18246877 ! vitamin metabolic process GO:0006766 44 44 0,000 0,17009297 0,18236262 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,17009297 0,1822566 ! amine biosynthetic process GO:0009309 46 45 0,000 0,17361364 0,18592094 ! regulation of DNA binding GO:0051101 47 45 0,000 0,17361364 0,18581298 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,17361364 0,18570513 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,17361364 0,18559741 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,17711989 0,18923592 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,17711989 0,18912628 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,17711989 0,18901677 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,17711989 0,18890738 ! sex differentiation GO:0007548 47 47 0,000 0,18061177 0,19252024 ! amine transport GO:0015837 47 47 0,000 0,18061177 0,19240896 ! rhythmic process GO:0048511 47 47 0,000 0,18061177 0,1922978 ! calcium ion transport GO:0006816 48 48 0,000 0,18408935 0,19588722 ! actin filament organization GO:0007015 50 48 0,000 0,18408935 0,19577419 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,18408935 0,19566128 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,18408935 0,19554851 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,18408935 0,19543587 ! DNA recombination GO:0006310 48 48 0,000 0,18408935 0,19532335 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,18755267 0,19888352 ! divalent metal ion transport GO:0070838 49 49 0,000 0,18755267 0,19876916 ! response to nutrient GO:0007584 49 49 0,000 0,18755267 0,19865492 ! response to bacterium GO:0009617 50 49 0,000 0,18755267 0,19854082 ! regulation of ligase activity GO:0051340 50 49 0,000 0,18755267 0,19842685 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,18755267 0,198313 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,18755267 0,19819929 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,19100179 0,20172854 GO:0006334|nucleosome assembly, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,19100179 0,201613 ! transcription initiation GO:0006352 50 50 0,000 0,19100179 0,2014976 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,19443678 0,20500399 ! positive regulation of immune response GO:0050778 51 51 0,000 0,19443678 0,20488678 ! rRNA metabolic process GO:0016072 51 51 0,000 0,19443678 0,2047697 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,19443678 0,20465276 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,19443678 0,20453595 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,19443678 0,20441927 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,19785768 0,20789721 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,19785768 0,20777875 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,19785768 0,20766042 ! sodium ion transport GO:0006814 53 53 0,000 0,20126455 0,21111586 ! tRNA metabolic process GO:0006399 53 53 0,000 0,20126455 0,21099577 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,20126455 0,21087582 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,20126455 0,210756 ! hormone metabolic process GO:0042445 55 54 0,000 0,20465745 0,21418721 ! sulfur metabolic process GO:0006790 55 54 0,000 0,20465745 0,21406565 ! nucleosome organization GO:0034728 55 55 0,000 0,20803643 0,21747654 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,20803643 0,21735326 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,20803643 0,21723011 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,21140155 0,22061895 ! regulation of binding GO:0051098 60 57 0,000 0,21475287 0,22398955 ! ATP metabolic process GO:0046034 57 57 0,000 0,21475287 0,22386286 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,21475287 0,22373631 ! innate immune response GO:0045087 58 58 0,000 0,21809042 0,22708511 ! carboxylic acid transport GO:0046942 59 59 0,000 0,22141429 0,23041588 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,22141429 0,23028585 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,22141429 0,23015597 ! potassium ion transport GO:0006813 60 60 0,000 0,2247245 0,2334652 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,2247245 0,23333367 ! protein polymerization GO:0051258 65 60 0,000 0,2247245 0,23320228 ! cellular respiration GO:0045333 62 61 0,000 0,22802113 0,23649012 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,22802113 0,23635711 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,22802113 0,23622425 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,22802113 0,23609154 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,22802113 0,23595898 ! lipid transport GO:0006869 62 62 0,000 0,23130422 0,23922204 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,23130422 0,23908787 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,23130422 0,23895385 ! regulation of secretion GO:0051046 65 63 0,000 0,23457382 0,24219583 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,23457382 0,24206022 ! glucose metabolic process GO:0006006 63 63 0,000 0,23457382 0,24192477 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,23457382 0,24178946 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,23457382 0,24165431 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,23783 0,24487189 ! angiogenesis GO:0001525 65 64 0,000 0,23783 0,24473517 ! anion transport GO:0006820 65 65 0,000 0,2410728 0,24793369 ! regulation of hormone levels GO:0010817 66 65 0,000 0,2410728 0,24779541 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,24430228 0,25097497 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,24430228 0,25083515 ! DNA packaging GO:0006323 66 66 0,000 0,24430228 0,25069549 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,24430228 0,25055598 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,24751849 0,25371333 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,25072147 0,25685363 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,25072147 0,25671093 ! regulation of translation GO:0006417 69 69 0,000 0,2539113 0,25983261 ! sensory perception of sound GO:0007605 71 69 0,000 0,2539113 0,25968841 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,25708801 0,26279157 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,26025166 0,26587794 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,26025166 0,26573064 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,26025166 0,2655835 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,26025166 0,26543653 ! secretion by cell GO:0032940 75 72 0,000 0,2634023 0,26850135 ! regulation of cytokine production GO:0001817 72 72 0,000 0,2634023 0,26835292 ! electron transport chain GO:0022900 75 74 0,000 0,26966475 0,27458129 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,26966475 0,27442967 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,27277667 0,27744338 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,27277667 0,27729035 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,27896215 0,28342185 ! regulation of protein modification process GO:0031399 79 78 0,000 0,28203581 0,28638677 ! microtubule-based movement GO:0007018 82 78 0,000 0,28203581 0,28622907 ! metal ion homeostasis GO:0055065 78 78 0,000 0,28203581 0,28607154 ! regulation of immune response GO:0050776 78 78 0,000 0,28203581 0,28591419 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,28814522 0,29194702 ! lipid catabolic process GO:0016042 82 81 0,000 0,29118107 0,29486083 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,29721531 0,30080605 ! ncRNA processing GO:0034470 83 83 0,000 0,29721531 0,30064095 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,29721531 0,30047604 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,3002138 0,30334103 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,30319994 0,30619041 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,30319994 0,30602272 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,30617378 0,3088551 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,30617378 0,30868614 ! male gamete generation GO:0048232 90 88 0,000 0,31208473 0,31447356 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,31208473 0,31430172 ! chemotaxis GO:0006935 90 89 0,000 0,31502194 0,31708653 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,31502194 0,31691344 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,32086008 0,32261054 ! DNA replication GO:0006260 91 91 0,000 0,32086008 0,32243464 ! visual perception GO:0007601 93 92 0,000 0,3237611 0,3251726 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,3237611 0,32499549 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,3237611 0,32481857 ! blood vessel development GO:0001568 95 94 0,000 0,3295273 0,33042373 ! epidermis development GO:0008544 94 94 0,000 0,3295273 0,33024405 ! cofactor metabolic process GO:0051186 95 94 0,000 0,3295273 0,33006457 ! vasculature development GO:0001944 97 96 0,000 0,33524601 0,33561021 ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,34091762 0,3411027 ! ectoderm development GO:0007398 99 99 0,000 0,34373587 0,34373587