pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6367-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! response to UV GO:0009411 75 46 5,000 2,96E-07 6,807E-04 ! serine family amino acid biosynthetic process GO:0009070 13 11 3,000 3,777E-07 4,344E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 5,555E-07 4,259E-04 ! glycine metabolic process GO:0006544 22 14 3,000 1,13E-06 6,498E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 4,000 3,316E-06 1,525E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 3,771E-06 1,446E-03 ! collagen catabolic process GO:0030574 25 20 3,000 5,321E-06 1,748E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 5,44E-06 1,564E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 7,036E-06 1,798E-03 ! negative regulation of DNA replication GO:0008156 35 23 3,000 9,593E-06 2,206E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,121E-05 2,344E-03 ! multicellular organismal catabolic process GO:0044243 32 26 3,000 1,598E-05 3,062E-03 ! serine family amino acid metabolic process GO:0009069 37 27 3,000 1,867E-05 3,303E-03 ! cell junction assembly GO:0034329 56 28 3,000 2,168E-05 3,562E-03 ! response to light stimulus GO:0009416 153 96 5,000 2,304E-05 3,533E-03 ! response to X-ray GO:0010165 16 10 2,000 2,381E-05 3,423E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 2,000 2,381E-05 3,221E-03 ! collagen metabolic process GO:0032963 40 30 3,000 2,875E-05 3,674E-03 ! mammary gland development GO:0030879 57 31 3,000 3,286E-05 3,978E-03 ! negative regulation of DNA metabolic process GO:0051053 48 32 3,000 3,739E-05 4,299E-03 ! cell junction organization GO:0034330 63 33 3,000 4,235E-05 4,638E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 3,000 4,235E-05 4,427E-03 ! response to gamma radiation GO:0010332 20 12 2,000 4,327E-05 4,327E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 7,098E-05 6,802E-03 ! multicellular organismal metabolic process GO:0044236 50 39 3,000 8,282E-05 7,62E-03 ! positive regulation of neuron apoptosis GO:0043525 29 15 2,000 8,834E-05 7,815E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 1,309E-04 0,01115013 ! cellular amino acid biosynthetic process GO:0008652 51 44 3,000 1,336E-04 0,01097544 ! positive regulation of cell cycle GO:0045787 77 45 3,000 1,46E-04 0,01157791 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 1,521E-04 0,01166221 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 1,564E-04 0,01160336 ! cell cycle arrest GO:0007050 150 86 4,000 1,607E-04 0,01155383 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 1,607E-04 0,01120372 ! interphase GO:0051325 159 88 4,000 1,791E-04 0,01211793 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 1,849E-04 0,01215155 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 1,849E-04 0,01181401 ! regulation of DNA replication GO:0006275 75 48 3,000 1,881E-04 0,01168996 ! hindlimb morphogenesis GO:0035137 32 20 2,000 2,166E-04 0,01311048 ! regulation of protein catabolic process GO:0042176 77 51 3,000 2,382E-04 0,01405016 ! cell aging GO:0007569 32 21 2,000 2,516E-04 0,01446807 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 2,516E-04 0,01411519 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 2,516E-04 0,01377911 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 2,901E-04 0,01551649 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 2,901E-04 0,01516384 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 3,322E-04 0,01697735 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 3,322E-04 0,01660828 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,464E-04 0,0169538 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 3,464E-04 0,0166006 ! epithelial cell proliferation GO:0050673 6 5 1,000 3,464E-04 0,01626181 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 3,464E-04 0,01593657 ! microvillus organization GO:0032528 7 5 1,000 3,464E-04 0,01562409 GO:0030033|microvillus assembly, ! early endosome to late endosome transport GO:0045022 11 5 1,000 3,464E-04 0,01532363 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,464E-04 0,0150345 ! regulation of centrosome cycle GO:0046605 7 5 1,000 3,464E-04 0,01475609 ! centrosome duplication GO:0051298 5 5 1,000 3,464E-04 0,01448779 ! response to UV-C GO:0010225 6 5 1,000 3,464E-04 0,01422908 ! negative regulation of multicellular organism growth GO:0040015 7 5 1,000 3,464E-04 0,01397945 ! transcription termination GO:0006353 8 5 1,000 3,464E-04 0,01373843 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 3,78E-04 0,01473484 ! embryonic limb morphogenesis GO:0030326 86 60 3,000 4,462E-04 0,01710523 GO:0035113|embryonic appendage morphogenesis, ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 4,814E-04 0,01815007 ! regulation of helicase activity GO:0051095 11 6 1,000 5,177E-04 0,01920322 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 5,177E-04 0,01889841 ! male meiosis GO:0007140 7 6 1,000 5,177E-04 0,01860312 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 5,177E-04 0,01831692 ! neuron adhesion GO:0007158 9 6 1,000 5,177E-04 0,01803939 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 5,177E-04 0,01777014 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 5,177E-04 0,01750882 ! ER overload response GO:0006983 7 6 1,000 5,177E-04 0,01725507 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 1,000 5,177E-04 0,01700857 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 5,177E-04 0,01676901 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 5,177E-04 0,01653611 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 5,177E-04 0,01630958 ! axonal fasciculation GO:0007413 9 6 1,000 5,177E-04 0,01608918 ! blastocyst growth GO:0001832 15 6 1,000 5,177E-04 0,01587466 ! response to ionizing radiation GO:0010212 47 27 2,000 5,392E-04 0,01631817 ! negative regulation of protein transport GO:0051224 49 27 2,000 5,392E-04 0,01610625 ! appendage morphogenesis GO:0035107 93 64 3,000 5,709E-04 0,01683531 GO:0035108|limb morphogenesis, ! BMP signaling pathway GO:0030509 40 28 2,000 6,013E-04 0,01750657 ! neural tube formation GO:0001841 41 28 2,000 6,013E-04 0,01728774 ! appendage development GO:0048736 94 65 3,000 6,056E-04 0,01719649 GO:0060173|limb development, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 7,219E-04 0,02024837 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 7,219E-04 0,02000442 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 7,219E-04 0,01976627 ! B cell lineage commitment GO:0002326 17 7 1,000 7,219E-04 0,01953373 ! transcription from RNA polymerase I promoter GO:0006360 12 7 1,000 7,219E-04 0,01930659 ! T cell lineage commitment GO:0002360 12 7 1,000 7,219E-04 0,01908467 ! response to tumor cell GO:0002347 12 7 1,000 7,219E-04 0,0188678 ! embryonic epithelial tube formation GO:0001838 44 30 2,000 7,388E-04 0,0190929 ! regulation of catabolic process GO:0009894 106 70 3,000 8,017E-04 0,020489 ! response to mechanical stimulus GO:0009612 43 31 2,000 8,144E-04 0,02058499 ! response to hypoxia GO:0001666 132 72 3,000 8,915E-04 0,0222863 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 9,588E-04 0,02371214 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 9,588E-04 0,02345989 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 9,588E-04 0,02321294 ! keratinocyte proliferation GO:0043616 12 8 1,000 9,588E-04 0,02297114 ! middle ear morphogenesis GO:0042474 9 8 1,000 9,588E-04 0,02273432 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 9,588E-04 0,02250234 ! multicellular organism growth GO:0035264 14 8 1,000 9,588E-04 0,02227504 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 9,588E-04 0,02205229 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 9,588E-04 0,02183395 ! regulation of telomere maintenance GO:0032204 10 8 1,000 9,588E-04 0,0216199 ! response to oxygen levels GO:0070482 137 74 3,000 9,88E-04 0,0220624 ! negative regulation of growth GO:0045926 123 75 3,000 1,039E-03 0,02297674 ! neuron migration GO:0001764 46 34 2,000 1,07E-03 0,02344482 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,07E-03 0,02322364 ! amine biosynthetic process GO:0009309 97 76 3,000 1,092E-03 0,0234665 ! gland development GO:0048732 148 77 3,000 1,146E-03 0,02441213 ! one-carbon metabolic process GO:0006730 110 77 3,000 1,146E-03 0,02418817 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 1,166E-03 0,02437193 ! protein complex disassembly GO:0043241 17 9 1,000 1,228E-03 0,0254441 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 1,000 1,228E-03 0,02521692 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 1,228E-03 0,02499376 ! receptor clustering GO:0043113 15 9 1,000 1,228E-03 0,02477452 ! motor axon guidance GO:0008045 14 9 1,000 1,228E-03 0,02455908 ! oocyte differentiation GO:0009994 12 9 1,000 1,228E-03 0,02434737 GO:0048599|oocyte development, ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 1,228E-03 0,02413927 ! localization within membrane GO:0051668 15 9 1,000 1,228E-03 0,0239347 ! neural tube development GO:0021915 50 36 2,000 1,266E-03 0,02447108 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 2,000 1,483E-03 0,02842605 ! pigmentation GO:0043473 74 38 2,000 1,483E-03 0,02819112 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,529E-03 0,02882523 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,529E-03 0,02859088 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,529E-03 0,0283603 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,529E-03 0,02813342 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 1,529E-03 0,02791014 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 1,529E-03 0,02769038 ! morphogenesis of embryonic epithelium GO:0016331 60 39 2,000 1,6E-03 0,02874618 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 1,654E-03 0,02949036 ! T cell differentiation GO:0030217 65 40 2,000 1,722E-03 0,03046744 ! double-strand break repair GO:0006302 67 40 2,000 1,722E-03 0,03023486 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,862E-03 0,03243561 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,862E-03 0,03219174 GO:0000725|recombinational repair, ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,862E-03 0,0319515 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 1,862E-03 0,03171482 ! regulation of mRNA processing GO:0050684 18 11 1,000 1,862E-03 0,03148162 ! focal adhesion formation GO:0048041 24 11 1,000 1,862E-03 0,03125183 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,862E-03 0,03102537 ! membrane protein proteolysis GO:0033619 18 11 1,000 1,862E-03 0,03080216 GO:0006509|membrane protein ectodomain proteolysis, ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,862E-03 0,03058215 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,862E-03 0,03036525 GO:0042130|negative regulation of T cell proliferation, ! protein processing GO:0016485 114 88 3,000 1,879E-03 0,03043749 ! regulation of neurogenesis GO:0050767 153 89 3,000 1,959E-03 0,03150399 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 1,984E-03 0,03168581 ! cellular component disassembly GO:0022411 64 42 2,000 1,984E-03 0,03146729 ! activation of caspase activity GO:0006919 65 43 2,000 2,123E-03 0,03345147 ! DNA-dependent DNA replication GO:0006261 59 43 2,000 2,123E-03 0,03322391 ! response to insulin stimulus GO:0032868 63 43 2,000 2,123E-03 0,03299942 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 2,123E-03 0,03277795 ! cell-cell junction assembly GO:0007043 18 12 1,000 2,225E-03 0,0341193 ! histone acetylation GO:0016573 23 12 1,000 2,225E-03 0,03389334 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,225E-03 0,03367036 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 2,269E-03 0,03410972 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 2,421E-03 0,03615309 ! protein maturation GO:0051604 129 96 3,000 2,582E-03 0,03831141 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,62E-03 0,03862177 ! endocrine pancreas development GO:0031018 19 13 1,000 2,62E-03 0,03837578 ! bone mineralization GO:0030282 15 13 1,000 2,62E-03 0,03813289 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 2,62E-03 0,03789306 ! regulation of cellular pH GO:0030641 20 13 1,000 2,62E-03 0,03765623 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,62E-03 0,03742234 ! response to estrogen stimulus GO:0043627 74 47 2,000 2,742E-03 0,03893621 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 2,742E-03 0,03869733 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 2,000 2,742E-03 0,03846137 ! extracellular structure organization GO:0043062 156 99 3,000 2,886E-03 0,0402331 ! positive regulation of caspase activity GO:0043280 72 48 2,000 2,913E-03 0,04035748 GO:0010952|positive regulation of peptidase activity, ! regulation of S phase GO:0033261 18 14 1,000 3,044E-03 0,04192786 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 3,044E-03 0,04167829 ! heterophilic cell adhesion GO:0007157 29 14 1,000 3,044E-03 0,04143167 ! cellular response to starvation GO:0009267 21 14 1,000 3,044E-03 0,04118796 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 3,044E-03 0,04094709 ! G1/S transition checkpoint GO:0031575 33 14 1,000 3,044E-03 0,04070903 ! regulation of intracellular transport GO:0032386 78 49 2,000 3,089E-03 0,04107329 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 3,499E-03 0,04625239 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 3,499E-03 0,04598809 ! lipid phosphorylation GO:0046834 23 15 1,000 3,499E-03 0,0457268 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 3,499E-03 0,04546845 ! centrosome cycle GO:0007098 16 15 1,000 3,499E-03 0,04521301 ! regulation of survival gene product expression GO:0045884 20 15 1,000 3,499E-03 0,04496043 ! neuron recognition GO:0008038 22 15 1,000 3,499E-03 0,04471065 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 3,499E-03 0,04446363 ! biomineral formation GO:0031214 18 15 1,000 3,499E-03 0,04421932 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 3,499E-03 0,04397768 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 3,499E-03 0,04373868 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! aging GO:0007568 79 52 2,000 3,658E-03 0,04548318 ! nucleotide-excision repair GO:0006289 64 52 2,000 3,658E-03 0,04523864 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,983E-03 0,0489949 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,983E-03 0,04873429 GO:0030968|endoplasmic reticulum unfolded protein response, ! protein export from nucleus GO:0006611 24 16 1,000 3,983E-03 0,04847644 ! DNA replication initiation GO:0006270 25 16 1,000 3,983E-03 0,0482213 ! oogenesis GO:0048477 23 16 1,000 3,983E-03 0,04796883 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 3,983E-03 0,04771899 ! signal complex assembly GO:0007172 29 17 1,000 4,497E-03 0,05359333 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 4,497E-03 0,05331708 ! forelimb morphogenesis GO:0035136 19 17 1,000 4,497E-03 0,05304365 ! memory GO:0007613 25 17 1,000 4,497E-03 0,05277302 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 4,497E-03 0,05250514 ! cellular macromolecular complex disassembly GO:0034623 29 17 1,000 4,497E-03 0,05223996 ! actin filament bundle formation GO:0051017 26 17 1,000 4,497E-03 0,05197745 ! neuromuscular junction development GO:0007528 23 17 1,000 4,497E-03 0,05171756 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 4,497E-03 0,05146026 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 4,497E-03 0,05120551 ! cell-cell junction organization GO:0045216 25 17 1,000 4,497E-03 0,05095326 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 4,511E-03 0,05085633 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 4,741E-03 0,05319142 ! developmental maturation GO:0021700 75 57 2,000 4,741E-03 0,05293321 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 5,04E-03 0,05599753 ! pancreas development GO:0031016 26 18 1,000 5,04E-03 0,05572831 ! pigmentation during development GO:0048066 31 18 1,000 5,04E-03 0,05546167 ! somitogenesis GO:0001756 24 18 1,000 5,04E-03 0,05519757 ! cellular response to nutrient levels GO:0031669 27 18 1,000 5,04E-03 0,05493597 ! negative regulation of T cell activation GO:0050868 25 18 1,000 5,04E-03 0,05467683 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 5,04E-03 0,05442013 ! actin filament organization GO:0007015 95 59 2,000 5,222E-03 0,05612945 ! protein import into nucleus, docking GO:0000059 30 19 1,000 5,611E-03 0,06002399 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 5,611E-03 0,0597461 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 5,611E-03 0,05947077 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 5,611E-03 0,05919797 ! response to alkaloid GO:0043279 32 19 1,000 5,611E-03 0,05892766 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 5,611E-03 0,05865981 ! apoptotic nuclear changes GO:0030262 24 19 1,000 5,611E-03 0,05839438 ! response to starvation GO:0042594 30 19 1,000 5,611E-03 0,05813134 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 5,611E-03 0,05787066 ! protein stabilization GO:0050821 26 19 1,000 5,611E-03 0,05761231 ! extracellular matrix organization GO:0030198 103 61 2,000 5,732E-03 0,0585979 ! negative regulation of cell growth GO:0030308 106 62 2,000 5,998E-03 0,06104323 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 6,21E-03 0,06292383 ! collagen fibril organization GO:0030199 45 20 1,000 6,21E-03 0,06264784 ! positive regulation of B cell activation GO:0050871 31 20 1,000 6,21E-03 0,06237427 ! regulation of transcription factor activity GO:0051090 97 63 2,000 6,271E-03 0,06271184 GO:0090046|regulation of transcription regulator activity, ! cell cycle checkpoint GO:0000075 108 64 2,000 6,552E-03 0,06523162 ! negative regulation of cell size GO:0045792 108 64 2,000 6,552E-03 0,06495045 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 6,838E-03 0,06749502 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 6,838E-03 0,06720657 ! protein amino acid acylation GO:0043543 37 21 1,000 6,838E-03 0,06692059 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 6,838E-03 0,06663703 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 6,838E-03 0,06635586 ! regulation of caspase activity GO:0043281 97 65 2,000 6,839E-03 0,06609339 ! axon guidance GO:0007411 99 66 2,000 7,134E-03 0,06865689 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 7,437E-03 0,0712705 ! regulation of neuron differentiation GO:0045664 107 67 2,000 7,437E-03 0,07097477 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 7,492E-03 0,07120765 ! leukocyte adhesion GO:0007159 38 22 1,000 7,492E-03 0,07091462 ! glutamate signaling pathway GO:0007215 34 22 1,000 7,492E-03 0,07062398 ! macromolecular complex disassembly GO:0032984 38 22 1,000 7,492E-03 0,07033572 ! microtubule organizing center organization GO:0031023 28 22 1,000 7,492E-03 0,0700498 GO:0051297|centrosome organization, ! blastocyst development GO:0001824 37 22 1,000 7,492E-03 0,0697662 ! neural tube closure GO:0001843 33 22 1,000 7,492E-03 0,06948489 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 1,000 7,492E-03 0,06920583 ! learning or memory GO:0007611 123 68 2,000 7,747E-03 0,07127238 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 8,174E-03 0,07490302 ! myelination GO:0042552 35 23 1,000 8,174E-03 0,07460579 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 8,174E-03 0,0743109 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 8,174E-03 0,07401834 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 8,174E-03 0,07372807 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 8,174E-03 0,07344007 ! negative regulation of catabolic process GO:0009895 34 23 1,000 8,174E-03 0,07315431 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 8,39E-03 0,07479297 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 8,39E-03 0,0745042 ! lymphocyte differentiation GO:0030098 113 71 2,000 8,723E-03 0,07716187 ! fat cell differentiation GO:0045444 37 24 1,000 8,883E-03 0,07827884 ! mitochondrial membrane organization GO:0007006 39 24 1,000 8,883E-03 0,07798006 ! receptor metabolic process GO:0043112 37 24 1,000 8,883E-03 0,07768356 ! primary neural tube formation GO:0014020 35 24 1,000 8,883E-03 0,07738931 ! negative regulation of cell development GO:0010721 56 24 1,000 8,883E-03 0,07709727 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 8,883E-03 0,07680743 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 8,883E-03 0,07651976 ! regulation of peptidase activity GO:0052547 106 72 2,000 9,063E-03 0,07778062 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 9,063E-03 0,07749147 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 116 73 2,000 9,411E-03 0,08017047 ! tube morphogenesis GO:0035239 118 73 2,000 9,411E-03 0,07987464 ! mitochondrion organization GO:0007005 104 73 2,000 9,411E-03 0,07958098 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 9,411E-03 0,07928948 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 9,618E-03 0,08073661 GO:0045936|negative regulation of phosphate metabolic process, ! iron ion homeostasis GO:0055072 39 25 1,000 9,618E-03 0,08044302 ! regulation of chromosome organization GO:0033044 35 25 1,000 9,618E-03 0,08015156 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 9,618E-03 0,07986221 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 9,618E-03 0,07957493 ! protein import into nucleus GO:0006606 118 74 2,000 9,767E-03 0,08051839 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 9,767E-03 0,08023082 ! nuclear import GO:0051170 121 75 2,000 0,01013091 0,08292203 ! regulation of pH GO:0006885 36 26 1,000 0,01037959 0,08465622 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01037959 0,08435708 ! regulation of protein transport GO:0051223 114 76 2,000 0,01050238 0,08505451 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 2,000 0,01088168 0,0878171 ! protein ubiquitination GO:0016567 125 77 2,000 0,01088168 0,08751004 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,01116682 0,08949019 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01116682 0,08917946 GO:0043433|negative regulation of transcription factor activity, ! T cell activation GO:0042110 134 79 2,000 0,01166388 0,0928267 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01197955 0,09501023 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01197955 0,09468373 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01197955 0,09435947 ! regulation of B cell activation GO:0050864 42 28 1,000 0,01197955 0,09403743 ! protein localization in nucleus GO:0034504 133 80 2,000 0,01206682 0,09440031 ! regulation of cAMP metabolic process GO:0030814 141 81 2,000 0,0124777 0,09728378 ! mRNA transport GO:0051028 121 81 2,000 0,0124777 0,09695512 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,0124777 0,09662867 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01281746 0,09892669 ! tissue homeostasis GO:0001894 42 29 1,000 0,01281746 0,09859583 GO:0048871|multicellular organismal homeostasis, ! ossification GO:0001503 134 82 2,000 0,01289654 0,09887346 GO:0060348|bone development, ! spindle organization GO:0007051 37 30 1,000 0,01368022 0,10453323 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01368022 0,10418709 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,01368022 0,10384324 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,01375817 0,10409141 ! transcription initiation GO:0006352 118 85 2,000 0,014201 0,10708953 ! regulation of protein localization GO:0032880 132 85 2,000 0,014201 0,10673957 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01456751 0,10913772 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,01456751 0,10878337 ! segmentation GO:0035282 41 31 1,000 0,01456751 0,10843132 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01456751 0,10808154 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01456751 0,10773401 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 2,000 0,01465188 0,10801062 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,0151108 0,11103785 GO:0060538|skeletal muscle organ development, ! regulation of muscle development GO:0048634 48 32 1,000 0,01547902 0,11338139 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01547902 0,11302145 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01547902 0,11266378 ! regulation of protein stability GO:0031647 48 32 1,000 0,01547902 0,11230838 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01547902 0,11195521 ! establishment of RNA localization GO:0051236 128 88 2,000 0,0155778 0,11231644 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of nucleotide metabolic process GO:0006140 150 89 2,000 0,01605289 0,11538011 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,01641444 0,11761125 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ear morphogenesis GO:0042471 42 33 1,000 0,01641444 0,117246 ! nucleus organization GO:0006997 49 33 1,000 0,01641444 0,11688301 ! female gonad development GO:0008585 49 33 1,000 0,01641444 0,11652226 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01641444 0,11616373 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01641444 0,1158074 ! cytokinesis GO:0000910 52 33 1,000 0,01641444 0,11545325 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 0,01653607 0,11595414 ! leukocyte differentiation GO:0002521 143 90 2,000 0,01653607 0,1156017 ! RNA localization GO:0006403 135 91 2,000 0,01702736 0,11867557 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01737345 0,12072184 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,01737345 0,12035822 ! female gamete generation GO:0007292 43 34 1,000 0,01737345 0,11999679 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,01737345 0,11963752 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,01803433 0,12381781 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01835574 0,12564942 ! maintenance of protein location GO:0045185 65 35 1,000 0,01835574 0,12527657 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01835574 0,12490593 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of binding GO:0051098 151 95 2,000 0,01907387 0,12940973 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01936101 0,13097156 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,01936101 0,13058748 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,01936101 0,13020564 GO:0046660|female sex differentiation, ! in utero embryonic development GO:0001701 147 96 2,000 0,01960587 0,13146793 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 2,000 0,01960587 0,13108576 ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 0,01960587 0,1307058 ! protein import GO:0017038 156 99 2,000 0,02125087 0,14126299 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,02143929 0,14210479 ! maintenance of location in cell GO:0051651 69 38 1,000 0,02143929 0,14169644 ! protein localization in organelle GO:0033365 161 100 2,000 0,02181554 0,14377005 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,02251169 0,14793399 ! chromatin remodeling GO:0006338 68 39 1,000 0,02251169 0,14751252 ! developmental growth GO:0048589 62 39 1,000 0,02251169 0,14709345 ! synapse organization GO:0050808 55 39 1,000 0,02251169 0,14667676 ! response to calcium ion GO:0051592 58 40 1,000 0,02360588 0,15337156 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,02360588 0,15293953 ! B cell differentiation GO:0030183 62 40 1,000 0,02360588 0,15250992 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,02360588 0,15208273 ! glucose transport GO:0015758 52 41 1,000 0,02472157 0,15882572 ! endosome transport GO:0016197 71 41 1,000 0,02472157 0,1583833 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02472157 0,15794335 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,02472157 0,15750583 ! mitochondrial transport GO:0006839 60 42 1,000 0,02585846 0,16429406 ! hexose transport GO:0008645 54 42 1,000 0,02585846 0,16384146 GO:0015749|monosaccharide transport, ! positive regulation of binding GO:0051099 59 43 1,000 0,02701626 0,17070715 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02701626 0,17023946 ! regulation of action potential GO:0001508 71 44 1,000 0,0281947 0,17717981 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,0281947 0,17669703 ! cell recognition GO:0008037 58 45 1,000 0,02939349 0,18370933 ! cell maturation GO:0048469 60 45 1,000 0,02939349 0,18321147 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,0293964 0,18273438 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,0293964 0,18224183 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,0293964 0,18175193 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,0293964 0,18126466 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,0293964 0,18078 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0293964 0,18029792 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,0293964 0,1798184 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,0293964 0,17934143 ! sleep GO:0030431 11 5 0,000 0,0293964 0,17886698 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0293964 0,17839504 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,0293964 0,17792558 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,0293964 0,17745858 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,0293964 0,17699403 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,0293964 0,1765319 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,0293964 0,17607219 ! tongue development GO:0043586 6 5 0,000 0,0293964 0,17561485 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,0293964 0,17515989 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,0293964 0,17470728 ! cobalt ion transport GO:0006824 9 5 0,000 0,0293964 0,17425701 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,0293964 0,17380905 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,0293964 0,17336338 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,0293964 0,17292 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,0293964 0,17247888 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,0293964 0,17204 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,0293964 0,17160335 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,0293964 0,17116891 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,0293964 0,17073666 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,0293964 0,1703066 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0293964 0,16987869 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0293964 0,16945293 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0293964 0,1690293 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,0293964 0,16860778 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0293964 0,16818836 ! malate metabolic process GO:0006108 7 5 0,000 0,0293964 0,16777102 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,0293964 0,16735574 ! behavioral response to pain GO:0048266 7 5 0,000 0,0293964 0,16694252 ! clathrin coat assembly GO:0048268 11 5 0,000 0,0293964 0,16653133 ! phototransduction, visible light GO:0007603 6 5 0,000 0,0293964 0,16612216 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0293964 0,165715 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,0293964 0,16530983 ! mating behavior GO:0007617 6 5 0,000 0,0293964 0,16490663 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0293964 0,1645054 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,0293964 0,16410611 ! rhythmic behavior GO:0007622 12 5 0,000 0,0293964 0,16370876 ! copulation GO:0007620 7 5 0,000 0,0293964 0,16331333 ! glial cell fate commitment GO:0021781 12 5 0,000 0,0293964 0,16291981 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,0293964 0,16252817 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,0293964 0,16213842 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,0293964 0,16175052 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,0293964 0,16136448 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,0293964 0,16098028 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,0293964 0,16059791 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,0293964 0,16021734 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0293964 0,15983858 ! response to protozoan GO:0001562 9 5 0,000 0,0293964 0,1594616 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,0293964 0,1590864 ! lymph vessel development GO:0001945 7 5 0,000 0,0293964 0,15871296 ! endochondral ossification GO:0001958 12 5 0,000 0,0293964 0,15834126 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,0293964 0,15797131 ! parathyroid gland development GO:0060017 8 5 0,000 0,0293964 0,15760307 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,0293964 0,15723656 ! anagen GO:0042640 6 5 0,000 0,0293964 0,15687174 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,0293964 0,15650861 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,0293964 0,15614716 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,0293964 0,15578737 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,0293964 0,15542924 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,0293964 0,15507275 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,0293964 0,15471789 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,0293964 0,15436466 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,0293964 0,15401303 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,0293964 0,153663 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,0293964 0,15331456 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,0293964 0,15296769 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,0293964 0,15262239 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,0293964 0,15227865 ! ovulation GO:0030728 6 5 0,000 0,0293964 0,15193645 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,0293964 0,15159578 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,0293964 0,15125664 ! response to pH GO:0009268 9 5 0,000 0,0293964 0,15091902 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,0293964 0,15058289 ! proline biosynthetic process GO:0006561 6 5 0,000 0,0293964 0,15024826 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0293964 0,14991512 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,0293964 0,14958345 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0293964 0,14925324 ! polyol catabolic process GO:0046174 7 5 0,000 0,0293964 0,14892449 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0293964 0,14859718 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0293964 0,14827131 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0293964 0,14794687 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,0293964 0,14762384 ! nerve growth factor processing GO:0032455 7 5 0,000 0,0293964 0,14730222 ! urea metabolic process GO:0019627 6 5 0,000 0,0293964 0,146982 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,0293964 0,14666317 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0293964 0,14634571 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,0293964 0,14602963 ! neutrophil activation GO:0042119 5 5 0,000 0,0293964 0,14571491 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,0293964 0,14540155 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,0293964 0,14508953 ! response to food GO:0032094 5 5 0,000 0,0293964 0,14477884 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,0293964 0,14446949 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0293964 0,14416145 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,0293964 0,14385472 ! forebrain neuron development GO:0021884 7 5 0,000 0,0293964 0,1435493 ! melanosome organization GO:0032438 7 5 0,000 0,0293964 0,14324517 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,0293964 0,14294232 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0293964 0,14264076 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,0293964 0,14234046 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0293964 0,14204143 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,0293964 0,14174365 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,0293964 0,14144711 ! nucleoside transport GO:0015858 6 5 0,000 0,0293964 0,14115181 ! nucleoside salvage GO:0043174 7 5 0,000 0,0293964 0,14085775 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,0293964 0,1405649 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0293964 0,14027328 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,0293964 0,13998286 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,0293964 0,13969363 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0293964 0,13940561 ! depyrimidination GO:0045008 8 5 0,000 0,0293964 0,13911876 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,0293964 0,1388331 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,0293964 0,1385486 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,0293964 0,13826527 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,0293964 0,1379831 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,0293964 0,13770208 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,0293964 0,13742219 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,0293964 0,13714345 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,0293964 0,13686583 ! monocyte differentiation GO:0030224 8 5 0,000 0,0293964 0,13658933 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,0293964 0,13631395 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0293964 0,13603968 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,0293964 0,1357665 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,0293964 0,13549443 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,0293964 0,13522344 ! regulation of dendrite development GO:0050773 12 5 0,000 0,0293964 0,13495353 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,0293964 0,1346847 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0293964 0,13441694 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,0293964 0,13415024 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,0293964 0,13388459 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,0293964 0,13362 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,0293964 0,13335645 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,0293964 0,13309394 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,0293964 0,13283245 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,0293964 0,132572 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0293964 0,13231256 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,0293964 0,13205414 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0293964 0,13179672 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0293964 0,13154031 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,0293964 0,13128489 ! neural tube patterning GO:0021532 6 5 0,000 0,0293964 0,13103046 ! histone demethylation GO:0016577 9 5 0,000 0,0293964 0,13077702 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0293964 0,13052455 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0293964 0,13027306 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,0293964 0,13002254 ! enteric nervous system development GO:0048484 8 5 0,000 0,0293964 0,12977297 ! establishment of planar polarity GO:0001736 6 5 0,000 0,0293964 0,12952437 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,0293964 0,12927671 ! muscle cell proliferation GO:0033002 8 5 0,000 0,0293964 0,12903 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,0293964 0,12878423 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,0293964 0,12853939 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,0293964 0,12829548 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,0293964 0,1280525 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,0293964 0,12781043 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0293964 0,12756928 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0293964 0,12732904 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,0293964 0,1270897 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,0293964 0,12685126 ! apical protein localization GO:0045176 6 5 0,000 0,0293964 0,12661371 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,0293964 0,12637705 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,0293964 0,12614127 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0293964 0,12590637 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0293964 0,12567234 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,0293964 0,12543918 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,0293964 0,12520689 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,0293964 0,12497545 ! glial cell migration GO:0008347 10 5 0,000 0,0293964 0,12474487 ! determination of adult lifespan GO:0008340 8 5 0,000 0,0293964 0,12451514 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,0293964 0,12428625 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0293964 0,1240582 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0293964 0,12383099 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,0293964 0,12360461 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,0293964 0,12337905 ! neural plate development GO:0001840 6 5 0,000 0,0293964 0,12315432 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,0293964 0,1229304 ! regulation of sensory perception GO:0051931 6 5 0,000 0,0293964 0,12270729 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,0293964 0,122485 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,0293964 0,12226351 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,0293964 0,12204281 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,0293964 0,12182292 ! sensory cilium assembly GO:0035058 6 5 0,000 0,0293964 0,12160381 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,0293964 0,12138549 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0293964 0,12116796 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,0293964 0,1209512 ! spindle assembly GO:0051225 5 5 0,000 0,0293964 0,12073521 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,0293964 0,12052 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,0293964 0,12030555 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,0293964 0,12009186 ! organ regeneration GO:0031100 7 5 0,000 0,0293964 0,11987893 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,0293964 0,11966676 ! carnitine metabolic process GO:0009437 5 5 0,000 0,0293964 0,11945533 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,0293964 0,11924465 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,0293964 0,11903472 GO:0055081|anion homeostasis, ! histone modification GO:0016570 68 46 1,000 0,03061236 0,12374063 ! endocrine system development GO:0035270 83 47 1,000 0,03185102 0,12852166 ! covalent chromatin modification GO:0016569 75 47 1,000 0,03185102 0,12829657 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,03185102 0,12807228 ! nuclear export GO:0051168 69 48 1,000 0,0331092 0,13289907 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,0331092 0,13266754 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,03438664 0,13754657 ! germ cell development GO:0007281 68 49 1,000 0,03438664 0,13730777 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,03438664 0,1370698 ! cartilage development GO:0051216 70 49 1,000 0,03438664 0,13683266 ! maintenance of location GO:0051235 84 49 1,000 0,03438664 0,13659633 ! tRNA transcription GO:0009304 11 6 0,000 0,03517215 0,13947576 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03517215 0,1392357 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03517215 0,13899647 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03517215 0,13875805 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03517215 0,13852045 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03517215 0,13828366 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03517215 0,13804768 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03517215 0,13781251 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03517215 0,13757813 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03517215 0,13734456 ! prostate gland development GO:0030850 9 6 0,000 0,03517215 0,13711177 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03517215 0,13687977 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03517215 0,13664855 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03517215 0,13641812 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03517215 0,13618846 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03517215 0,13595957 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03517215 0,13573145 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03517215 0,13550409 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03517215 0,1352775 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03517215 0,13505166 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03517215 0,13482657 ! signal peptide processing GO:0006465 8 6 0,000 0,03517215 0,13460223 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03517215 0,13437864 ! mRNA stabilization GO:0048255 15 6 0,000 0,03517215 0,13415579 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03517215 0,13393368 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03517215 0,1337123 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03517215 0,13349166 ! opsonization GO:0008228 8 6 0,000 0,03517215 0,13327173 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03517215 0,13305254 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03517215 0,13283406 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03517215 0,1326163 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03517215 0,13239925 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03517215 0,13218291 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03517215 0,13196728 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03517215 0,13175235 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03517215 0,13153812 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03517215 0,13132458 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03517215 0,13111174 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03517215 0,13089958 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03517215 0,13068811 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03517215 0,13047733 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03517215 0,13026722 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03517215 0,13005779 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03517215 0,12984903 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03517215 0,12964093 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03517215 0,12943351 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03517215 0,12922675 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03517215 0,12902064 ! thymic T cell selection GO:0045061 12 6 0,000 0,03517215 0,1288152 ! protein lipoylation GO:0009249 10 6 0,000 0,03517215 0,1286104 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03517215 0,12840626 ! pigment granule organization GO:0048753 11 6 0,000 0,03517215 0,12820276 ! drug transport GO:0015893 6 6 0,000 0,03517215 0,12799991 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03517215 0,1277977 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03517215 0,12759612 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03517215 0,12739519 ! histidine metabolic process GO:0006547 6 6 0,000 0,03517215 0,12719488 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03517215 0,1269952 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03517215 0,12679615 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03517215 0,12659772 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03517215 0,12639991 ! adenohypophysis development GO:0021984 10 6 0,000 0,03517215 0,12620272 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03517215 0,12600614 ! hyperosmotic response GO:0006972 8 6 0,000 0,03517215 0,12581018 ! microtubule nucleation GO:0007020 10 6 0,000 0,03517215 0,12561482 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03517215 0,12542007 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03517215 0,12522592 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03517215 0,12503237 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03517215 0,12483942 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03517215 0,12464706 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03517215 0,1244553 ! response to dietary excess GO:0002021 7 6 0,000 0,03517215 0,12426412 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03517215 0,12407353 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03517215 0,12388353 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03517215 0,1236941 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03517215 0,12350526 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03517215 0,12331699 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03517215 0,12312929 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03517215 0,12294216 ! neuron apoptosis GO:0051402 8 6 0,000 0,03517215 0,1227556 ! organic alcohol transport GO:0015850 9 6 0,000 0,03517215 0,12256961 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03517215 0,12238418 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03517215 0,12219931 ! male sex determination GO:0030238 9 6 0,000 0,03517215 0,122015 ! carnitine transport GO:0015879 8 6 0,000 0,03517215 0,12183124 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03517215 0,12164803 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03517215 0,12146538 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03517215 0,12128327 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03517215 0,12110171 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03517215 0,12092069 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03517215 0,12074021 ! parturition GO:0007567 12 6 0,000 0,03517215 0,12056027 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03517215 0,12038087 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03517215 0,120202 ! spindle checkpoint GO:0031577 14 6 0,000 0,03517215 0,12002365 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03517215 0,11984584 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03517215 0,11966855 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03517215 0,11949179 ! macrophage differentiation GO:0030225 10 6 0,000 0,03517215 0,11931555 ! astrocyte development GO:0014002 14 6 0,000 0,03517215 0,11913983 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03517215 0,11896462 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03517215 0,11878993 ! interaction with symbiont GO:0051702 8 6 0,000 0,03517215 0,11861575 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03517215 0,11844208 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03517215 0,11826892 ! eating behavior GO:0042755 6 6 0,000 0,03517215 0,11809627 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03517215 0,11792412 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03517215 0,11775246 ! response to copper ion GO:0046688 9 6 0,000 0,03517215 0,11758131 ! DNA topological change GO:0006265 8 6 0,000 0,03517215 0,11741066 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03517215 0,1172405 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03517215 0,11707083 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03517215 0,11690165 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03517215 0,11673296 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03517215 0,11656476 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03517215 0,11639704 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03517215 0,1162298 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03517215 0,11606305 ! gas homeostasis GO:0033483 11 6 0,000 0,03517215 0,11589677 ! hair follicle maturation GO:0048820 7 6 0,000 0,03517215 0,11573096 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03517215 0,11556563 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03517215 0,11540077 ! Schwann cell development GO:0014044 14 6 0,000 0,03517215 0,11523639 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03517215 0,11507247 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03517215 0,11490901 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03517215 0,11474602 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03517215 0,11458349 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03517215 0,11442142 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03517215 0,11425981 ! histone ubiquitination GO:0016574 7 6 0,000 0,03517215 0,11409865 ! regulation of meiosis GO:0040020 10 6 0,000 0,03517215 0,11393795 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03517215 0,1137777 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03517215 0,1136179 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03517215 0,11345855 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03517215 0,11329964 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03517215 0,11314118 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03517215 0,11298316 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03517215 0,11282558 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03517215 0,11266844 ! receptor internalization GO:0031623 9 6 0,000 0,03517215 0,11251174 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03517215 0,11235548 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03517215 0,11219964 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03517215 0,11204424 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03517215 0,11188927 ! protein deubiquitination GO:0016579 8 6 0,000 0,03517215 0,11173473 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03517215 0,11158061 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03517215 0,11142692 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03517215 0,11127365 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03517215 0,1111208 ! midbrain development GO:0030901 6 6 0,000 0,03517215 0,11096837 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03517215 0,11081636 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03517215 0,11066476 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03517215 0,11051358 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03517215 0,11036281 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03517215 0,11021246 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03517215 0,11006251 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03517215 0,10991297 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03517215 0,10976383 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03517215 0,1096151 ! adult feeding behavior GO:0008343 6 6 0,000 0,03517215 0,10946677 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03517215 0,10931884 ! pigment granule transport GO:0051904 12 6 0,000 0,03517215 0,10917131 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03517215 0,10902418 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03517215 0,10887745 ! catecholamine transport GO:0051937 7 6 0,000 0,03517215 0,10873111 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03517215 0,10858516 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03517215 0,1084396 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03517215 0,10829444 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03517215 0,10814966 ! protein prenylation GO:0018342 10 6 0,000 0,03517215 0,10800526 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03517215 0,10786126 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03517215 0,10771763 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03517215 0,10757439 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03517215 0,10743153 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03517215 0,10728905 ! ear development GO:0043583 72 50 1,000 0,03568306 0,10870337 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,03568306 0,10855958 ! lipid modification GO:0030258 73 50 1,000 0,03568306 0,10841617 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,03568306 0,10827314 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,0369982 0,11211576 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,0369982 0,11196824 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,0369982 0,1118211 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,0369982 0,11167436 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,03833179 0,11554799 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03968357 0,11946626 ! cell projection assembly GO:0030031 76 53 1,000 0,03968357 0,11931009 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04091386 0,1228484 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04091386 0,12268823 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04091386 0,12252848 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04091386 0,12236914 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04091386 0,12221022 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04091386 0,12205172 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04091386 0,12189362 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04091386 0,12173593 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04091386 0,12157865 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04091386 0,12142177 ! reproductive behavior GO:0019098 12 7 0,000 0,04091386 0,1212653 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04091386 0,12110923 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,04091386 0,12095356 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04091386 0,1207983 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,04091386 0,12064343 ! oligopeptide transport GO:0006857 11 7 0,000 0,04091386 0,12048895 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04091386 0,12033488 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04091386 0,12018119 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04091386 0,1200279 ! RNA methylation GO:0001510 11 7 0,000 0,04091386 0,119875 ! pericardium development GO:0060039 8 7 0,000 0,04091386 0,11972248 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04091386 0,11957036 ! fibril organization GO:0043206 13 7 0,000 0,04091386 0,11941862 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,04091386 0,11926727 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04091386 0,11911629 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04091386 0,1189657 ! lipoprotein transport GO:0042953 9 7 0,000 0,04091386 0,1188155 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04091386 0,11866567 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04091386 0,11851621 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04091386 0,11836714 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04091386 0,11821843 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04091386 0,1180701 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04091386 0,11792215 ! chemosensory behavior GO:0007635 9 7 0,000 0,04091386 0,11777456 ! microtubule bundle formation GO:0001578 8 7 0,000 0,04091386 0,11762734 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,04091386 0,11748049 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04091386 0,11733401 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04091386 0,11718789 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04091386 0,11704213 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04091386 0,11689674 ! reflex GO:0060004 12 7 0,000 0,04091386 0,1167517 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04091386 0,11660703 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04091386 0,11646271 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04091386 0,11631875 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04091386 0,11617515 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04091386 0,1160319 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04091386 0,11588901 ! spinal cord patterning GO:0021511 7 7 0,000 0,04091386 0,11574646 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04091386 0,11560427 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04091386 0,11546242 ! adrenal gland development GO:0030325 17 7 0,000 0,04091386 0,11532092 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04091386 0,11517977 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04091386 0,11503896 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04091386 0,1148985 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04091386 0,11475838 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04091386 0,1146186 ! endosome organization GO:0007032 10 7 0,000 0,04091386 0,11447916 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04091386 0,11434006 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04091386 0,1142013 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04091386 0,11406288 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04091386 0,11392478 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04091386 0,11378703 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04091386 0,1136496 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04091386 0,11351251 ! galactose metabolic process GO:0006012 10 7 0,000 0,04091386 0,11337575 ! vesicle fusion GO:0006906 15 7 0,000 0,04091386 0,11323932 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04091386 0,11310321 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04091386 0,11296743 ! organ growth GO:0035265 11 7 0,000 0,04091386 0,11283198 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04091386 0,11269685 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,04091386 0,11256205 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04091386 0,11242757 ! retinol metabolic process GO:0042572 9 7 0,000 0,04091386 0,1122934 ! behavioral fear response GO:0001662 13 7 0,000 0,04091386 0,11215956 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04091386 0,11202604 ! rRNA modification GO:0000154 12 7 0,000 0,04091386 0,11189283 ! protein heterooligomerization GO:0051291 10 7 0,000 0,04091386 0,11175994 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04091386 0,11162737 ! response to UV-B GO:0010224 11 7 0,000 0,04091386 0,11149511 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04091386 0,11136316 ! intermediate filament organization GO:0045109 11 7 0,000 0,04091386 0,11123153 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04091386 0,1111002 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04091386 0,11096919 ! fibrinolysis GO:0042730 9 7 0,000 0,04091386 0,11083848 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,04091386 0,11070809 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04091386 0,11057799 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04091386 0,11044821 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04091386 0,11031872 ! response to tropane GO:0014073 13 7 0,000 0,04091386 0,11018955 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04091386 0,11006067 ! melanosome localization GO:0032400 10 7 0,000 0,04091386 0,10993209 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04091386 0,10980382 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04091386 0,10967584 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04091386 0,10954816 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04091386 0,10942078 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04091386 0,1092937 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04091386 0,10916691 ! mast cell activation GO:0045576 9 7 0,000 0,04091386 0,10904041 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04091386 0,1089142 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04091386 0,10878829 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04091386 0,10866267 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04091386 0,10853734 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04091386 0,1084123 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04091386 0,10828754 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04091386 0,10816307 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04091386 0,10803889 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04091386 0,10791499 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04091386 0,10779138 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04091386 0,10766805 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04091386 0,107545 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04091386 0,10742223 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04091386 0,10729974 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04091386 0,10717753 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,04091386 0,1070556 ! diuresis GO:0030146 12 7 0,000 0,04091386 0,10693395 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04091386 0,10681257 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04091386 0,10669147 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04091386 0,10657064 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04091386 0,10645008 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04091386 0,1063298 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04091386 0,10620979 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04091386 0,10609005 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04091386 0,10597058 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04091386 0,10585138 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04091386 0,10573244 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04091386 0,10561377 ! lymph node development GO:0048535 9 7 0,000 0,04091386 0,10549537 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04091386 0,10537724 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04091386 0,10525937 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04091386 0,10514176 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04091386 0,10502441 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04091386 0,10490733 ! ATP catabolic process GO:0006200 10 7 0,000 0,04091386 0,1047905 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04091386 0,10467394 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04091386 0,10455764 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04091386 0,10444159 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04091386 0,1043258 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04091386 0,10421027 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04091386 0,10409499 ! muscle adaptation GO:0043500 12 7 0,000 0,04091386 0,10397997 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04091386 0,1038652 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04091386 0,10375069 ! retina homeostasis GO:0001895 9 7 0,000 0,04091386 0,10363642 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04091386 0,10352241 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04091386 0,10340865 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04091386 0,10329514 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04091386 0,10318188 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04091386 0,10306886 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,04091386 0,1029561 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04091386 0,10284358 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,04105329 0,1030814 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,04105329 0,10296899 ! DNA catabolic process GO:0006308 67 54 1,000 0,04105329 0,10285682 ! detection of external stimulus GO:0009581 66 54 1,000 0,04105329 0,1027449 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,04105329 0,10263322 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,04384549 0,10949472 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,04526747 0,1129232 ! carbohydrate transport GO:0008643 74 57 1,000 0,04526747 0,11280086 ! gonad development GO:0008406 79 57 1,000 0,04526747 0,11267878 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04662172 0,11592429 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04662172 0,1157991 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04662172 0,11567418 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04662172 0,11554953 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04662172 0,11542515 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04662172 0,11530104 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04662172 0,11517719 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04662172 0,11505361 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04662172 0,11493029 ! phosphate transport GO:0006817 10 8 0,000 0,04662172 0,11480724 ! N-glycan processing GO:0006491 12 8 0,000 0,04662172 0,11468445 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04662172 0,11456193 ! UTP metabolic process GO:0046051 8 8 0,000 0,04662172 0,11443966 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04662172 0,11431766 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04662172 0,11419592 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04662172 0,11407443 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04662172 0,1139532 ! succinate metabolic process GO:0006105 14 8 0,000 0,04662172 0,11383223 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,04662172 0,11371152 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04662172 0,11359106 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04662172 0,11347086 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04662172 0,11335091 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04662172 0,11323122 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04662172 0,11311178 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04662172 0,11299259 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04662172 0,11287365 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04662172 0,11275496 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04662172 0,11263652 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04662172 0,11251833 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04662172 0,11240038 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04662172 0,11228269 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04662172 0,11216523 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04662172 0,11204803 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04662172 0,11193107 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04662172 0,11181435 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04662172 0,11169788 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04662172 0,11158165 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04662172 0,11146566 ! melanin metabolic process GO:0006582 12 8 0,000 0,04662172 0,11134991 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04662172 0,1112344 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04662172 0,11111913 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04662172 0,1110041 ! macrophage activation GO:0042116 12 8 0,000 0,04662172 0,11088931 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04662172 0,11077476 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04662172 0,11066044 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04662172 0,11054635 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04662172 0,11043251 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04662172 0,11031889 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04662172 0,11020551 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04662172 0,11009237 ! ruffle organization GO:0031529 11 8 0,000 0,04662172 0,10997945 ! osteoblast development GO:0002076 13 8 0,000 0,04662172 0,10986677 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04662172 0,10975431 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04662172 0,10964209 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04662172 0,1095301 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04662172 0,10941833 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04662172 0,10930679 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04662172 0,10919548 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04662172 0,1090844 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04662172 0,10897354 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04662172 0,10886291 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04662172 0,1087525 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04662172 0,10864231 ! segment specification GO:0007379 10 8 0,000 0,04662172 0,10853235 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04662172 0,10842261 ! cellular extravasation GO:0045123 11 8 0,000 0,04662172 0,1083131 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04662172 0,1082038 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04662172 0,10809472 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04662172 0,10798587 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04662172 0,10787723 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04662172 0,10776881 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04662172 0,10766061 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04662172 0,10755262 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04662172 0,10744485 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04662172 0,1073373 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04662172 0,10722996 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04662172 0,10712284 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04662172 0,10701593 ! icosanoid secretion GO:0032309 12 8 0,000 0,04662172 0,10690924 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04662172 0,10680275 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04662172 0,10669648 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04662172 0,10659042 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04662172 0,10648457 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04662172 0,10637893 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04662172 0,1062735 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04662172 0,10616828 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04662172 0,10606327 ! sterol catabolic process GO:0016127 9 8 0,000 0,04662172 0,10595846 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04662172 0,10585386 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04662172 0,10574947 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04662172 0,10564528 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04662172 0,1055413 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04662172 0,10543753 ! prophase GO:0051324 11 8 0,000 0,04662172 0,10533395 ! S phase GO:0051320 8 8 0,000 0,04662172 0,10523058 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04662172 0,10512742 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04662172 0,10502445 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04662172 0,10492169 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04662172 0,10481912 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04662172 0,10471676 ! hormone catabolic process GO:0042447 13 8 0,000 0,04662172 0,1046146 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04662172 0,10451264 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04662172 0,10441087 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04662172 0,1043093 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04662172 0,10420793 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04662172 0,10410676 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04662172 0,10400578 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04662172 0,103905 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04662172 0,10380442 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04662172 0,10370403 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04662172 0,10360383 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04662172 0,10350383 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04662172 0,10340402 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04662172 0,1033044 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04662172 0,10320497 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04662172 0,10310573 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,04670638 0,10319373 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,04670638 0,10309469 ! lung development GO:0030324 94 59 1,000 0,04816195 0,10620565 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,04963396 0,10934684 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,04963396 0,1092422 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,04963396 0,10913776 ! meiosis GO:0007126 96 61 1,000 0,05112214 0,1123027 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,05112214 0,11219555 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,05112214 0,11208859 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,05112214 0,11198184 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05229594 0,11444403 ! regulation of developmental growth GO:0048638 13 9 0,000 0,05229594 0,11433524 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,05229594 0,11422666 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05229594 0,11411829 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,05229594 0,11401012 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05229594 0,11390215 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05229594 0,11379439 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05229594 0,11368684 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05229594 0,11357948 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,05229594 0,11347233 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,05229594 0,11336538 ! GTP metabolic process GO:0046039 9 9 0,000 0,05229594 0,11325864 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05229594 0,11315209 ! social behavior GO:0035176 14 9 0,000 0,05229594 0,11304575 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05229594 0,1129396 ! artery development GO:0060840 19 9 0,000 0,05229594 0,11283365 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05229594 0,1127279 ! regulation of glycolysis GO:0006110 15 9 0,000 0,05229594 0,11262235 ! response to pain GO:0048265 16 9 0,000 0,05229594 0,112517 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05229594 0,11241184 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,05229594 0,11230688 ! lung alveolus development GO:0048286 17 9 0,000 0,05229594 0,11220212 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05229594 0,11209755 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05229594 0,11199318 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05229594 0,111889 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05229594 0,11178501 ! protein targeting to ER GO:0045047 19 9 0,000 0,05229594 0,11168122 ! T cell selection GO:0045058 18 9 0,000 0,05229594 0,11157762 ! endoderm development GO:0007492 12 9 0,000 0,05229594 0,11147421 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05229594 0,11137099 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05229594 0,11126797 ! arginine catabolic process GO:0006527 10 9 0,000 0,05229594 0,11116513 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,05229594 0,11106249 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05229594 0,11096003 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,05229594 0,11085776 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05229594 0,11075568 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,05229594 0,11065379 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,05229594 0,11055209 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,05229594 0,11045057 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,05229594 0,11034924 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05229594 0,1102481 ! mannose metabolic process GO:0006013 9 9 0,000 0,05229594 0,11014714 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05229594 0,11004636 ! epithelial cell development GO:0002064 10 9 0,000 0,05229594 0,10994577 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05229594 0,10984536 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05229594 0,10974514 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05229594 0,1096451 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05229594 0,10954524 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05229594 0,10944556 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05229594 0,10934607 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,05229594 0,10924675 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05229594 0,10914762 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,05229594 0,10904866 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05229594 0,10894988 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05229594 0,10885129 ! DNA ligation GO:0006266 14 9 0,000 0,05229594 0,10875287 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05229594 0,10865463 ! response to amine stimulus GO:0014075 13 9 0,000 0,05229594 0,10855656 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,05229594 0,10845868 ! erythrocyte development GO:0048821 11 9 0,000 0,05229594 0,10836097 ! renal water homeostasis GO:0003091 14 9 0,000 0,05229594 0,10826343 ! postreplication repair GO:0006301 11 9 0,000 0,05229594 0,10816607 ! mRNA cleavage GO:0006379 13 9 0,000 0,05229594 0,10806889 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05229594 0,10797188 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,05229594 0,10787504 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05229594 0,10777838 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05229594 0,10768189 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05229594 0,10758558 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05229594 0,10748943 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,05229594 0,10739346 ! acid secretion GO:0046717 14 9 0,000 0,05229594 0,10729766 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05229594 0,10720203 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,05229594 0,10710657 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05229594 0,10701127 ! purine base metabolic process GO:0006144 18 9 0,000 0,05229594 0,10691615 ! thymus development GO:0048538 15 9 0,000 0,05229594 0,1068212 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05229594 0,10672642 ! spleen development GO:0048536 15 9 0,000 0,05229594 0,1066318 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05229594 0,10653735 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05229594 0,10644307 ! detection of calcium ion GO:0005513 13 9 0,000 0,05229594 0,10634896 ! blastocyst formation GO:0001825 12 9 0,000 0,05229594 0,10625501 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05229594 0,10616123 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05229594 0,10606761 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,05229594 0,10597416 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05229594 0,10588087 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05229594 0,10578775 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05229594 0,10569479 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,05229594 0,105602 ! prepulse inhibition GO:0060134 14 9 0,000 0,05229594 0,10550936 ! embryonic placenta development GO:0001892 12 9 0,000 0,05229594 0,10541689 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05229594 0,10532458 ! insulin secretion GO:0030073 17 9 0,000 0,05229594 0,10523243 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05229594 0,10514045 ! response to nicotine GO:0035094 16 9 0,000 0,05229594 0,10504862 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05229594 0,10495696 ! nucleus localization GO:0051647 15 9 0,000 0,05229594 0,10486545 ! regulation of synapse organization GO:0050807 12 9 0,000 0,05229594 0,10477411 ! respiratory tube development GO:0030323 99 62 1,000 0,05262628 0,10534416 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,05262628 0,10525255 ! meiotic cell cycle GO:0051321 97 62 1,000 0,05262628 0,10516111 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,05414612 0,10810423 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,05414612 0,10801047 ! regulation of lipase activity GO:0060191 109 63 1,000 0,05414612 0,10791687 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,05568143 0,11088076 ! respiratory system development GO:0060541 100 64 1,000 0,05568143 0,11078484 ! reproductive structure development GO:0048608 90 65 1,000 0,05723197 0,11377142 ! B cell activation GO:0042113 104 65 1,000 0,05723197 0,11367317 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,05723197 0,11357509 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,05723197 0,11347719 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,05723197 0,11337944 ! protein oligomerization GO:0051259 100 65 1,000 0,05723197 0,11328187 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05793672 0,1145782 ! neuron fate specification GO:0048665 11 10 0,000 0,05793672 0,11447977 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05793672 0,1143815 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05793672 0,1142834 ! thyroid gland development GO:0030878 19 10 0,000 0,05793672 0,11418548 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05793672 0,11408771 ! synapsis GO:0007129 13 10 0,000 0,05793672 0,11399012 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05793672 0,11389269 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05793672 0,11379543 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05793672 0,11369834 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05793672 0,11360141 ! sulfate transport GO:0008272 12 10 0,000 0,05793672 0,11350464 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05793672 0,11340804 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05793672 0,11331161 ! androgen metabolic process GO:0008209 13 10 0,000 0,05793672 0,11321534 ! phospholipid efflux GO:0033700 16 10 0,000 0,05793672 0,11311923 ! hippocampus development GO:0021766 19 10 0,000 0,05793672 0,11302328 ! blood vessel remodeling GO:0001974 21 10 0,000 0,05793672 0,1129275 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05793672 0,11283188 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05793672 0,11273642 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05793672 0,11264112 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05793672 0,11254599 ! pathogenesis GO:0009405 13 10 0,000 0,05793672 0,11245101 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05793672 0,1123562 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05793672 0,11226154 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05793672 0,11216705 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,05793672 0,11207271 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05793672 0,11197853 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05793672 0,11188451 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05793672 0,11179065 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05793672 0,11169694 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05793672 0,11160339 ! B cell proliferation GO:0042100 14 10 0,000 0,05793672 0,11151 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05793672 0,11141676 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05793672 0,11132368 ! forebrain cell migration GO:0021885 17 10 0,000 0,05793672 0,11123076 ! lipid digestion GO:0044241 15 10 0,000 0,05793672 0,11113799 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05793672 0,11104538 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05793672 0,11095291 ! UV protection GO:0009650 14 10 0,000 0,05793672 0,11086061 ! entry into host cell GO:0030260 20 10 0,000 0,05793672 0,11076845 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05793672 0,11067645 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05793672 0,11058461 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05793672 0,11049291 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05793672 0,11040137 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05793672 0,11030998 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05793672 0,11021873 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05793672 0,11012764 ! regulation of organ growth GO:0046620 11 10 0,000 0,05793672 0,11003671 ! response to dsRNA GO:0043331 18 10 0,000 0,05793672 0,10994592 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05793672 0,10985528 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05793672 0,10976479 ! embryonic axis specification GO:0000578 12 10 0,000 0,05793672 0,10967444 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05793672 0,10958425 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05793672 0,10949421 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05793672 0,10940431 ! cranial nerve development GO:0021545 12 10 0,000 0,05793672 0,10931456 ! fucose catabolic process GO:0019317 16 10 0,000 0,05793672 0,10922496 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05793672 0,1091355 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05793672 0,10904619 ! protein sumoylation GO:0016925 12 10 0,000 0,05793672 0,10895703 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05793672 0,10886801 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05793672 0,10877914 ! zymogen activation GO:0031638 14 10 0,000 0,05793672 0,10869042 ! salivary gland development GO:0007431 22 10 0,000 0,05793672 0,10860183 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05793672 0,1085134 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05793672 0,1084251 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05793672 0,10833695 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05793672 0,10824894 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,05793672 0,10816108 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05793672 0,10807336 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05793672 0,10798578 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05793672 0,10789834 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05793672 0,10781104 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05793672 0,10772389 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05793672 0,10763687 ! detection of bacterium GO:0016045 10 10 0,000 0,05793672 0,10755 ! embryonic gut development GO:0048566 11 10 0,000 0,05793672 0,10746327 ! activation of innate immune response GO:0002218 10 10 0,000 0,05793672 0,10737667 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05793672 0,10729022 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05793672 0,1072039 ! developmental induction GO:0031128 13 10 0,000 0,05793672 0,10711773 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05793672 0,10703169 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05793672 0,10694579 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05793672 0,10686002 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,05879752 0,10836082 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,06197272 0,11412111 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,06197272 0,11402981 ! rRNA transcription GO:0009303 17 11 0,000 0,06354424 0,11682793 ! respiratory burst GO:0045730 14 11 0,000 0,06354424 0,11673462 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,06354424 0,11664146 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,06354424 0,11654844 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,06354424 0,11645557 ! virus-host interaction GO:0019048 17 11 0,000 0,06354424 0,11636285 ! filopodium assembly GO:0046847 19 11 0,000 0,06354424 0,11627028 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,06354424 0,11617786 ! RNA polyadenylation GO:0043631 19 11 0,000 0,06354424 0,11608558 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,06354424 0,11599345 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,06354424 0,11590146 ! T cell proliferation GO:0042098 20 11 0,000 0,06354424 0,11580962 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,06354424 0,11571793 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,06354424 0,11562638 ! bone resorption GO:0045453 16 11 0,000 0,06354424 0,11553498 ! regulated secretory pathway GO:0045055 14 11 0,000 0,06354424 0,11544372 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,06354424 0,1153526 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,06354424 0,11526163 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,06354424 0,1151708 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,06354424 0,11508011 ! syncytium formation GO:0006949 15 11 0,000 0,06354424 0,11498957 ! plasma membrane organization GO:0007009 18 11 0,000 0,06354424 0,11489917 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,06354424 0,11480891 ! mitotic spindle organization GO:0007052 15 11 0,000 0,06354424 0,1147188 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,06354424 0,11462882 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,06354424 0,11453899 ! adult heart development GO:0007512 11 11 0,000 0,06354424 0,11444929 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,06354424 0,11435974 ! temperature homeostasis GO:0001659 16 11 0,000 0,06354424 0,11427032 ! L-glutamate transport GO:0015813 16 11 0,000 0,06354424 0,11418105 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,06354424 0,11409192 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,06354424 0,11400292 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,06354424 0,11391406 ! stem cell development GO:0048864 29 11 0,000 0,06354424 0,11382535 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,06354424 0,11373677 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,06354424 0,11364832 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,06354424 0,11356002 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,06354424 0,11347185 ! vasoconstriction GO:0042310 15 11 0,000 0,06354424 0,11338382 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,06354424 0,11329593 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,06354424 0,11320817 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,06354424 0,11312055 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,06354424 0,11303306 ! ribosome assembly GO:0042255 13 11 0,000 0,06354424 0,11294571 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,06354424 0,11285849 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,06354424 0,11277141 ! chromatin silencing GO:0006342 19 11 0,000 0,06354424 0,11268446 ! nucleosome positioning GO:0016584 13 11 0,000 0,06354424 0,11259765 ! T cell homeostasis GO:0043029 20 11 0,000 0,06354424 0,11251097 ! regulation of isotype switching GO:0045191 19 11 0,000 0,06354424 0,11242442 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,06354424 0,11233801 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,06354424 0,11225172 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,06354424 0,11216558 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,06354424 0,11207956 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,06354424 0,11199367 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,06354424 0,11190792 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,06354424 0,1118223 ! male genitalia development GO:0030539 13 11 0,000 0,06354424 0,11173681 ! cholesterol efflux GO:0033344 19 11 0,000 0,06354424 0,11165145 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,06354424 0,11156622 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,06354424 0,11148112 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,06354424 0,11139615 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,06354424 0,11131131 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,06354424 0,11122659 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,06354424 0,11114201 ! defense response to fungus GO:0050832 12 11 0,000 0,06354424 0,11105756 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,06354424 0,11097323 ! lysogeny GO:0030069 18 11 0,000 0,06354424 0,11088903 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,06354424 0,11080496 ! acrosome reaction GO:0007340 13 11 0,000 0,06354424 0,11072102 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,06354424 0,1106372 ! response to drug GO:0042493 108 69 1,000 0,06358192 0,11061907 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,06358192 0,11053546 ! response to metal ion GO:0010038 103 70 1,000 0,06520522 0,1132719 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,06684239 0,1160283 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,06684239 0,1159408 ! lactation GO:0007595 20 12 0,000 0,0691187 0,1197988 ! reproductive cellular process GO:0048610 14 12 0,000 0,0691187 0,11970859 ! tRNA modification GO:0006400 14 12 0,000 0,0691187 0,11961851 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0691187 0,11952857 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0691187 0,11943877 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0691187 0,1193491 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0691187 0,11925957 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0691187 0,11917017 ! non-recombinational repair GO:0000726 19 12 0,000 0,0691187 0,1190809 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0691187 0,11899177 ! peroxisomal transport GO:0043574 21 12 0,000 0,0691187 0,11890277 ! cartilage condensation GO:0001502 18 12 0,000 0,0691187 0,1188139 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0691187 0,11872517 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0691187 0,11863657 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0691187 0,1185481 ! heart looping GO:0001947 15 12 0,000 0,0691187 0,11845976 ! palate development GO:0060021 15 12 0,000 0,0691187 0,11837156 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,0691187 0,11828349 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0691187 0,11819554 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,0691187 0,11810773 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0691187 0,11802005 ! arginine metabolic process GO:0006525 13 12 0,000 0,0691187 0,1179325 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0691187 0,11784507 ! methionine metabolic process GO:0006555 13 12 0,000 0,0691187 0,11775778 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0691187 0,11767062 ! Golgi organization GO:0007030 18 12 0,000 0,0691187 0,11758358 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0691187 0,11749668 ! monoamine transport GO:0015844 13 12 0,000 0,0691187 0,1174099 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0691187 0,11732325 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,0691187 0,11723673 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0691187 0,11715033 ! L-amino acid transport GO:0015807 20 12 0,000 0,0691187 0,11706407 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0691187 0,11697793 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0691187 0,11689191 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0691187 0,11680603 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0691187 0,11672027 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0691187 0,11663463 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0691187 0,11654912 ! cerebellum development GO:0021549 13 12 0,000 0,0691187 0,11646374 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0691187 0,11637848 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0691187 0,11629335 ! histone methylation GO:0016571 15 12 0,000 0,0691187 0,11620834 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0691187 0,11612345 ! gland morphogenesis GO:0022612 23 12 0,000 0,0691187 0,11603869 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0691187 0,11595405 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0691187 0,11586954 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0691187 0,11578515 ! intestinal absorption GO:0050892 19 12 0,000 0,0691187 0,11570088 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0691187 0,11561673 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0691187 0,11553271 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0691187 0,1154488 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,0691187 0,11536502 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0691187 0,11528137 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0691187 0,11519783 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,0691187 0,11511441 ! microspike assembly GO:0030035 23 12 0,000 0,0691187 0,11503112 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0691187 0,11494794 ! response to cold GO:0009409 14 12 0,000 0,0691187 0,11486489 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,07183502 0,11929281 ! response to inorganic substance GO:0010035 115 75 1,000 0,07352554 0,12201208 ! response to nutrient GO:0007584 104 75 1,000 0,07352554 0,12192411 ! regulation of ligase activity GO:0051340 114 75 1,000 0,07352554 0,12183627 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,07466029 0,12362755 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,07466029 0,12353861 ! cGMP metabolic process GO:0046068 16 13 0,000 0,07466029 0,1234498 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,07466029 0,12336111 ! water transport GO:0006833 17 13 0,000 0,07466029 0,12327256 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,07466029 0,12318413 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,07466029 0,12309582 ! lipid localization GO:0010876 24 13 0,000 0,07466029 0,12300764 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,07466029 0,12291959 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,07466029 0,12283167 ! organelle fusion GO:0048284 28 13 0,000 0,07466029 0,12274387 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,07466029 0,12265619 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,07466029 0,12256864 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,07466029 0,12248122 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,07466029 0,12239392 ! response to hexose stimulus GO:0009746 19 13 0,000 0,07466029 0,12230675 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,07466029 0,1222197 ! glutamate metabolic process GO:0006536 18 13 0,000 0,07466029 0,12213277 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,07466029 0,12204596 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,07466029 0,12195928 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,07466029 0,12187273 ! NAD metabolic process GO:0019674 21 13 0,000 0,07466029 0,12178629 ! exocrine system development GO:0035272 27 13 0,000 0,07466029 0,12169998 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,07466029 0,12161379 ! regulation of exocytosis GO:0017157 17 13 0,000 0,07466029 0,12152772 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,07466029 0,12144178 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,07466029 0,12135595 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,07466029 0,12127025 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,07466029 0,12118467 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,07466029 0,1210992 ! genitalia development GO:0048806 15 13 0,000 0,07466029 0,12101386 ! cellular pigmentation GO:0033059 24 13 0,000 0,07466029 0,12092864 ! tissue regeneration GO:0042246 21 13 0,000 0,07466029 0,12084354 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,07466029 0,12075856 ! cofactor transport GO:0051181 19 13 0,000 0,07466029 0,1206737 ! NADP metabolic process GO:0006739 18 13 0,000 0,07466029 0,12058895 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,07466029 0,12050433 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,07466029 0,12041983 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07466029 0,12033544 ! gas transport GO:0015669 18 13 0,000 0,07466029 0,12025117 ! regulation of RNA stability GO:0043487 28 13 0,000 0,07466029 0,12016702 ! heme biosynthetic process GO:0006783 20 13 0,000 0,07466029 0,12008299 ! regulation of axon extension GO:0030516 23 13 0,000 0,07466029 0,11999907 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,07466029 0,11991527 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,07466029 0,11983159 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,07466029 0,11974803 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,07466029 0,11966458 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,07466029 0,11958125 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,07466029 0,11949803 ! response to unfolded protein GO:0006986 99 76 1,000 0,07522887 0,12032434 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,07694479 0,12298334 ! sex differentiation GO:0007548 105 77 1,000 0,07694479 0,12289793 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,07867311 0,12557123 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,07867311 0,12548415 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,08016921 0,12778184 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,08016921 0,12769334 ! superoxide anion generation GO:0042554 18 14 0,000 0,08016921 0,12760497 ! neuron maturation GO:0042551 21 14 0,000 0,08016921 0,12751673 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,08016921 0,1274286 ! myotube differentiation GO:0014902 21 14 0,000 0,08016921 0,1273406 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,08016921 0,12725272 ! inositol metabolic process GO:0006020 20 14 0,000 0,08016921 0,12716496 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,08016921 0,12707732 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,08016921 0,1269898 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,08016921 0,1269024 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,08016921 0,12681512 ! gene silencing by RNA GO:0031047 20 14 0,000 0,08016921 0,12672796 ! response to cAMP GO:0051591 19 14 0,000 0,08016921 0,12664093 ! limbic system development GO:0021761 25 14 0,000 0,08016921 0,12655401 ! startle response GO:0001964 21 14 0,000 0,08016921 0,12646721 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,08016921 0,12638053 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,08016921 0,12629396 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,08016921 0,12620752 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,08016921 0,1261212 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,08016921 0,12603499 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,08016921 0,1259489 ! pituitary gland development GO:0021983 23 14 0,000 0,08016921 0,12586293 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,08016921 0,12577707 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,08016921 0,12569133 ! regulation of heart rate GO:0002027 23 14 0,000 0,08016921 0,12560571 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,08016921 0,12552021 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,08016921 0,12543482 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,08016921 0,12534955 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,08016921 0,12526439 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,08016921 0,12517935 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,08016921 0,12509443 ! axon cargo transport GO:0008088 27 14 0,000 0,08016921 0,12500962 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,08016921 0,12492492 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,08016921 0,12484034 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,08016921 0,12475588 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,08016921 0,12467153 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08016921 0,12458729 ! mRNA splice site selection GO:0006376 26 14 0,000 0,08016921 0,12450317 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,08016921 0,12441916 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,08016921 0,12433526 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,08016921 0,12425147 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,08016921 0,1241678 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,08016921 0,12408425 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,08016921 0,1240008 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,08016921 0,12391747 ! muscle maintenance GO:0046716 19 14 0,000 0,08016921 0,12383424 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,08016921 0,12375113 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,08016921 0,12366813 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,08016921 0,12358525 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,08016921 0,12350247 ! cell killing GO:0001906 20 14 0,000 0,08016921 0,1234198 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,08016921 0,12333725 ! cilium assembly GO:0042384 20 14 0,000 0,08016921 0,12325481 ! peptide hormone secretion GO:0030072 23 14 0,000 0,08016921 0,12317247 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,08041361 0,12346548 ! regulation of lyase activity GO:0051339 133 79 1,000 0,08041361 0,12338312 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,08216609 0,125988 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 1,000 0,08393035 0,12860747 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,08393035 0,12852184 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,08564565 0,13106121 ! positive regulation of cell size GO:0045793 20 15 0,000 0,08564565 0,13097406 ! metencephalon development GO:0022037 19 15 0,000 0,08564565 0,13088704 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,08564565 0,13080013 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,08564565 0,13071333 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,08564565 0,13062665 ! skin development GO:0043588 25 15 0,000 0,08564565 0,13054009 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,08564565 0,13045364 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,08564565 0,1303673 ! bile acid metabolic process GO:0008206 22 15 0,000 0,08564565 0,13028108 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,08564565 0,13019497 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,08564565 0,13010898 ! adult walking behavior GO:0007628 25 15 0,000 0,08564565 0,1300231 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,08564565 0,12993733 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,08564565 0,12985168 ! myoblast differentiation GO:0045445 27 15 0,000 0,08564565 0,12976614 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,08564565 0,12968071 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,08564565 0,12959539 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,08564565 0,12951019 ! cerebral cortex development GO:0021987 29 15 0,000 0,08564565 0,12942509 ! response to osmotic stress GO:0006970 22 15 0,000 0,08564565 0,12934011 ! vesicle coating GO:0006901 25 15 0,000 0,08564565 0,12925525 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,08564565 0,12917049 ! DNA integration GO:0015074 22 15 0,000 0,08564565 0,12908584 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,08564565 0,12900131 ! peptide secretion GO:0002790 27 15 0,000 0,08564565 0,12891688 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,08564565 0,12883257 ! regulation of vasodilation GO:0042312 24 15 0,000 0,08564565 0,12874836 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,08564565 0,12866427 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,08564565 0,12858028 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,08564565 0,12849641 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,08564565 0,12841264 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,08564565 0,12832899 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,08564565 0,12824544 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,08564565 0,128162 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,08564565 0,12807867 ! dopamine metabolic process GO:0042417 30 15 0,000 0,08564565 0,12799545 ! organic cation transport GO:0015695 19 15 0,000 0,08564565 0,12791233 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,08564565 0,12782933 GO:0033014|tetrapyrrole biosynthetic process, ! defense response to virus GO:0051607 27 15 0,000 0,08564565 0,12774643 ! peptide hormone processing GO:0016486 19 15 0,000 0,08564565 0,12766364 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,08564565 0,12758095 ! detection of stimulus GO:0051606 108 82 1,000 0,0857062 0,12758851 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,08749343 0,13016487 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,08749343 0,13008073 ! protein secretion GO:0009306 27 16 0,000 0,09108979 0,13534013 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,09108979 0,13525276 ! hormone secretion GO:0046879 25 16 0,000 0,09108979 0,1351655 ! bone remodeling GO:0046849 24 16 0,000 0,09108979 0,13507835 ! endothelial cell migration GO:0043542 22 16 0,000 0,09108979 0,13499132 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,09108979 0,13490439 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09108979 0,13481758 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,09108979 0,13473088 ! glial cell development GO:0021782 24 16 0,000 0,09108979 0,1346443 ! patterning of blood vessels GO:0001569 24 16 0,000 0,09108979 0,13455782 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,09108979 0,13447145 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,09108979 0,1343852 ! protein polyubiquitination GO:0000209 26 16 0,000 0,09108979 0,13429905 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,09108979 0,13421302 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,09108979 0,1341271 ! fructose metabolic process GO:0006000 20 16 0,000 0,09108979 0,13404128 ! regulation of protein binding GO:0043393 27 16 0,000 0,09108979 0,13395558 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,09108979 0,13386998 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,09108979 0,1337845 ! negative regulation of immune response GO:0050777 28 16 0,000 0,09108979 0,13369912 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,09108979 0,13361385 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,09108979 0,1335287 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,09108979 0,13344365 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,09108979 0,1333587 ! diencephalon development GO:0021536 25 16 0,000 0,09108979 0,13327387 ! neural crest cell migration GO:0001755 24 16 0,000 0,09108979 0,13318914 ! G1 phase GO:0051318 27 16 0,000 0,09108979 0,13310453 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,09108979 0,13302001 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,09108979 0,13293561 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,09108979 0,13285131 ! steroid catabolic process GO:0006706 22 16 0,000 0,09108979 0,13276713 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,09108979 0,13268304 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,09108979 0,13259907 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,09108979 0,1325152 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,09108979 0,13243143 ! sperm-egg recognition GO:0035036 16 16 0,000 0,09108979 0,13234777 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,09108979 0,13226422 ! nerve development GO:0021675 18 16 0,000 0,09108979 0,13218077 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,09108979 0,13209743 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,09108979 0,13201419 ! negative regulation of translation GO:0017148 22 16 0,000 0,09108979 0,13193106 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,09110127 0,13186464 ! regulation of membrane potential GO:0042391 128 85 1,000 0,09110127 0,13178171 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,09110127 0,13169888 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,09475233 0,13689093 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,09650183 0,13933096 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,09650183 0,13924355 ! negative regulation of defense response GO:0031348 19 17 0,000 0,09650183 0,13915625 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,09650183 0,13906905 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,09650183 0,13898197 ! glycerol metabolic process GO:0006071 20 17 0,000 0,09650183 0,138895 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,09650183 0,13880814 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,09650183 0,13872138 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,09650183 0,13863474 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,09650183 0,1385482 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,09650183 0,13846177 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,09650183 0,13837544 ! keratinization GO:0031424 17 17 0,000 0,09650183 0,13828923 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,09650183 0,13820312 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,09650183 0,13811712 ! retinoid metabolic process GO:0001523 22 17 0,000 0,09650183 0,13803123 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,09650183 0,13794544 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,09650183 0,13785976 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,09650183 0,13777418 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,09650183 0,13768872 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,09650183 0,13760335 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,09650183 0,1375181 ! membrane budding GO:0006900 29 17 0,000 0,09650183 0,13743295 ! heme metabolic process GO:0042168 27 17 0,000 0,09650183 0,1373479 ! body fluid secretion GO:0007589 27 17 0,000 0,09650183 0,13726296 ! stem cell differentiation GO:0048863 36 17 0,000 0,09650183 0,13717813 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,09650183 0,1370934 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,09650183 0,13700877 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,09650183 0,13692425 ! sensory perception of pain GO:0019233 23 17 0,000 0,09650183 0,13683983 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,09650183 0,13675552 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,09650183 0,13667131 ! synaptogenesis GO:0007416 24 17 0,000 0,09650183 0,13658721 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,09650183 0,13650321 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,09650183 0,13641931 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,09650183 0,13633551 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,09650183 0,13625182 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,09650183 0,13616823 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,09650183 0,13608474 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,09650183 0,13600136 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,09650183 0,13591807 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,09650183 0,13583489 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,0965936 0,1358809 ! reproductive developmental process GO:0003006 127 89 1,000 0,09844511 0,13840082 ! regulation of T cell activation GO:0050863 128 89 1,000 0,09844511 0,13831628 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,10188195 0,14305769 ! positive regulation of translation GO:0045727 28 18 0,000 0,10188195 0,1429704 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,10188195 0,14288323 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,10188195 0,14279615 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,10188195 0,14270919 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,10188195 0,14262233 ! cAMP metabolic process GO:0046058 33 18 0,000 0,10188195 0,14253558 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,10188195 0,14244893 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,10188195 0,14236239 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,10188195 0,14227595 ! axis specification GO:0009798 26 18 0,000 0,10188195 0,14218962 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,10188195 0,14210339 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,10188195 0,14201727 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,10188195 0,14193125 ! glutamine metabolic process GO:0006541 23 18 0,000 0,10188195 0,14184533 ! response to retinoic acid GO:0032526 25 18 0,000 0,10188195 0,14175952 ! central nervous system neuron development GO:0021954 30 18 0,000 0,10188195 0,14167381 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,10188195 0,14158821 ! fucose metabolic process GO:0006004 26 18 0,000 0,10188195 0,14150271 ! response to fungus GO:0009620 19 18 0,000 0,10188195 0,14141731 ! peptide cross-linking GO:0018149 31 18 0,000 0,10188195 0,14133202 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,10188195 0,14124683 ! heart process GO:0003015 27 18 0,000 0,10188195 0,14116174 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,10188195 0,14107675 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,10188195 0,14099187 ! visual learning GO:0008542 35 18 0,000 0,10188195 0,14090709 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,10188195 0,14082241 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,10188195 0,14073783 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,10188195 0,14065335 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,10188195 0,14056898 ! vitamin transport GO:0051180 24 18 0,000 0,10188195 0,14048471 ! hormone transport GO:0009914 27 18 0,000 0,10188195 0,14040053 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,10188195 0,14031646 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,10188195 0,14023249 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,10188195 0,14014862 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,10188195 0,14006485 ! cell-cell recognition GO:0009988 20 18 0,000 0,10188195 0,13998118 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,10188195 0,13989761 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,10188195 0,13981413 ! regulation of glucose import GO:0046324 21 18 0,000 0,10188195 0,13973076 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,10188195 0,13964749 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,10188195 0,13956432 ! response to virus GO:0009615 122 91 1,000 0,10217812 0,13988672 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,10405926 0,14237734 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,10405926 0,14229269 ! cell fate commitment GO:0045165 141 92 1,000 0,10405926 0,14220814 ! DNA recombination GO:0006310 146 92 1,000 0,10405926 0,1421237 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,10594992 0,14462007 ! positive regulation of ossification GO:0045778 30 19 0,000 0,10723034 0,14628101 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,10723034 0,1461943 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,10723034 0,14610769 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,10723034 0,14602119 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,10723034 0,14593478 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,10723034 0,14584848 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,10723034 0,14576228 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,10723034 0,14567619 ! regeneration GO:0031099 32 19 0,000 0,10723034 0,14559019 ! sensory perception of taste GO:0050909 23 19 0,000 0,10723034 0,1455043 ! smooth muscle contraction GO:0006939 36 19 0,000 0,10723034 0,14541851 ! peroxisome organization GO:0007031 29 19 0,000 0,10723034 0,14533281 ! digestive system process GO:0022600 30 19 0,000 0,10723034 0,14524722 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,10723034 0,14516173 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,10723034 0,14507634 ! response to vitamin A GO:0033189 26 19 0,000 0,10723034 0,14499106 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,10723034 0,14490587 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,10723034 0,14482078 ! sex determination GO:0007530 29 19 0,000 0,10723034 0,14473579 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,10723034 0,1446509 ! plasma membrane fusion GO:0045026 23 19 0,000 0,10723034 0,14456611 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,10723034 0,14448142 ! cytolysis GO:0019835 20 19 0,000 0,10723034 0,14439683 ! renal system process GO:0003014 35 19 0,000 0,10723034 0,14431234 ! vasodilation GO:0042311 33 19 0,000 0,10723034 0,14422794 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,10723034 0,14414365 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,10723034 0,14405945 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,10723034 0,14397536 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,10723034 0,14389136 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,10723034 0,14380746 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,10723034 0,14372365 ! sarcomere organization GO:0045214 23 19 0,000 0,10723034 0,14363994 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,10723034 0,14355634 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,10723034 0,14347282 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,10723034 0,14338941 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,10723034 0,14330609 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,10723034 0,14322287 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,10723034 0,14313975 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,10723034 0,14305672 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,10723034 0,14297379 ! angiogenesis GO:0001525 149 95 1,000 0,10975908 0,14626065 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,11254719 0,14988913 ! iron ion transport GO:0006826 37 20 0,000 0,11254719 0,14980239 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,11254719 0,14971575 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,11254719 0,14962921 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,11254719 0,14954277 ! response to vitamin GO:0033273 29 20 0,000 0,11254719 0,14945642 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,11254719 0,14937018 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,11254719 0,14928404 ! spinal cord development GO:0021510 31 20 0,000 0,11254719 0,149198 ! response to ethanol GO:0045471 37 20 0,000 0,11254719 0,14911205 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,11254719 0,14902621 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,11254719 0,14894046 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,11254719 0,14885482 ! chromosome condensation GO:0030261 31 20 0,000 0,11254719 0,14876927 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,11254719 0,14868382 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,11254719 0,14859847 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,11254719 0,14851321 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,11254719 0,14842805 ! pallium development GO:0021543 38 20 0,000 0,11254719 0,148343 ! DNA modification GO:0006304 28 20 0,000 0,11254719 0,14825803 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,11254719 0,14817317 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,11254719 0,1480884 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,11254719 0,14800373 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,11254719 0,14791916 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,11254719 0,14783468 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,11254719 0,1477503 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,11254719 0,14766602 ! alditol metabolic process GO:0019400 24 20 0,000 0,11254719 0,14758183 ! actin filament-based movement GO:0030048 34 20 0,000 0,11254719 0,14749774 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,11360421 0,14879822 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,11783267 0,1542488 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,11783267 0,15416106 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,11783267 0,15407341 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,11783267 0,15398587 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,11783267 0,15389843 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,11783267 0,15381109 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,11783267 0,15372384 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,11783267 0,1536367 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,11783267 0,15354965 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,11783267 0,1534627 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,11783267 0,15337586 ! vesicle docking GO:0048278 27 21 0,000 0,11783267 0,1532891 ! phototransduction GO:0007602 25 21 0,000 0,11783267 0,15320245 ! dendrite development GO:0016358 35 21 0,000 0,11783267 0,1531159 ! visual behavior GO:0007632 39 21 0,000 0,11783267 0,15302944 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,11783267 0,15294308 ! ovarian follicle development GO:0001541 30 21 0,000 0,11783267 0,15285682 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,11783267 0,15277065 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,11783267 0,15268458 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,11783267 0,15259861 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,11783267 0,15251274 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,11783267 0,15242696 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,11783267 0,15234128 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,11783267 0,15225569 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,11783267 0,15217021 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,11783267 0,15208481 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,11783267 0,15199952 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,11783267 0,15191431 ! fatty acid transport GO:0015908 30 21 0,000 0,11783267 0,15182921 ! immunoglobulin production GO:0002377 33 21 0,000 0,11783267 0,1517442 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,11783267 0,15165928 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,11783267 0,15157446 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,11783267 0,15148973 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,11783267 0,1514051 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,11783267 0,15132057 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,11783267 0,15123612 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,11783267 0,15115178 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,11783267 0,15106752 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,11783267 0,15098336 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,11783267 0,1508993 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,11783267 0,15081532 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,11783267 0,15073144 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,11783267 0,15064766 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,11783267 0,15056396 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,11943635 0,15252837 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,11943635 0,15244373 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,12308697 0,1570161 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,12308697 0,15692907 ! viral genome replication GO:0019079 29 22 0,000 0,12308697 0,15684212 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,12308697 0,15675528 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,12308697 0,15666853 ! molting cycle process GO:0022404 40 22 0,000 0,12308697 0,15658188 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,12308697 0,15649532 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,12308697 0,15640886 ! vasculogenesis GO:0001570 33 22 0,000 0,12308697 0,15632249 ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,12308697 0,15623622 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,12308697 0,15615005 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,12308697 0,15606397 ! lysosome organization GO:0007040 37 22 0,000 0,12308697 0,15597798 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,12308697 0,15589209 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,12308697 0,15580629 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,12308697 0,15572059 ! regulation of behavior GO:0050795 38 22 0,000 0,12308697 0,15563498 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,12308697 0,15554947 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,12308697 0,15546405 ! membrane depolarization GO:0051899 35 22 0,000 0,12308697 0,15537872 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,12308697 0,15529349 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,12308697 0,15520835 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,12308697 0,15512331 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,12308697 0,15503835 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,12308697 0,15495349 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,12308697 0,15486873 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,12831028 0,16135246 ! neuron fate commitment GO:0048663 32 23 0,000 0,12831028 0,16126429 ! embryonic pattern specification GO:0009880 31 23 0,000 0,12831028 0,16117621 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,12831028 0,16108823 ! vesicle targeting GO:0006903 32 23 0,000 0,12831028 0,16100035 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,12831028 0,16091256 ! osteoblast differentiation GO:0001649 40 23 0,000 0,12831028 0,16082487 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,12831028 0,16073728 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,12831028 0,16064978 ! interaction with host GO:0051701 37 23 0,000 0,12831028 0,16056237 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,12831028 0,16047506 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,12831028 0,16038785 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,12831028 0,16030073 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,12831028 0,1602137 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,12831028 0,16012677 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,12831028 0,16003994 ! cell fate determination GO:0001709 45 23 0,000 0,12831028 0,15995319 ! pentose metabolic process GO:0019321 31 23 0,000 0,12831028 0,15986655 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,12831028 0,15977999 ! spermatid development GO:0007286 33 23 0,000 0,12831028 0,15969353 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,12831028 0,15960716 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,12831028 0,15952089 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,12831028 0,15943471 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,12831028 0,15934862 ! telomere organization GO:0032200 32 23 0,000 0,12831028 0,15926262 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,12831028 0,15917672 ! regulation of amine transport GO:0051952 38 23 0,000 0,12831028 0,15909091 ! liver development GO:0001889 40 23 0,000 0,12831028 0,1590052 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,13350277 0,16535077 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,13350277 0,16526177 ! initiation of viral infection GO:0019059 42 24 0,000 0,13350277 0,16517288 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,13350277 0,16508407 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,13350277 0,16499537 ! superoxide metabolic process GO:0006801 32 24 0,000 0,13350277 0,16490675 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,13350277 0,16481824 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,13350277 0,16472982 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,13350277 0,16464149 ! sperm motility GO:0030317 27 24 0,000 0,13350277 0,16455326 ! vacuole organization GO:0007033 39 24 0,000 0,13350277 0,16446512 ! neural crest cell development GO:0014032 39 24 0,000 0,13350277 0,16437708 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,13350277 0,16428913 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,13350277 0,16420127 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,13350277 0,16411351 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,13350277 0,16402584 ! glutathione metabolic process GO:0006749 29 24 0,000 0,13350277 0,16393827 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,13350277 0,16385079 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,13350277 0,1637634 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,13350277 0,16367611 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,13866463 0,16991404 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,13866463 0,16982356 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,13866463 0,16973318 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,13866463 0,1696429 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,13866463 0,16955271 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,13866463 0,16946262 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,13866463 0,16937262 ! peptide transport GO:0015833 43 25 0,000 0,13866463 0,16928272 ! male gonad development GO:0008584 33 25 0,000 0,13866463 0,16919292 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,13866463 0,16910321 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,13866463 0,16901359 ! phospholipid transport GO:0015914 35 25 0,000 0,13866463 0,16892407 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,13866463 0,16883465 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,13866463 0,16874532 ! detection of light stimulus GO:0009583 30 25 0,000 0,13866463 0,16865608 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,13866463 0,16856694 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,13866463 0,16847789 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,14379603 0,17462031 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,14379603 0,17452817 ! translational initiation GO:0006413 43 26 0,000 0,14379603 0,17443611 ! circadian rhythm GO:0007623 42 26 0,000 0,14379603 0,17434416 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,14379603 0,1742523 ! post-embryonic development GO:0009791 42 26 0,000 0,14379603 0,17416054 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,14379603 0,17406888 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,14379603 0,17397731 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,14379603 0,17388584 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,14379603 0,17379447 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,14379603 0,17370319 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,14379603 0,17361201 ! regulation of coagulation GO:0050818 39 26 0,000 0,14379603 0,17352092 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,14889716 0,17958231 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,14889716 0,17948819 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,14889716 0,17939416 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,14889716 0,17930024 ! membrane docking GO:0022406 39 27 0,000 0,14889716 0,17920641 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,14889716 0,17911269 ! catechol metabolic process GO:0009712 43 27 0,000 0,14889716 0,17901906 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,14889716 0,17892553 ! acute-phase response GO:0006953 42 27 0,000 0,14889716 0,17883209 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,14889716 0,17873876 ! myofibril assembly GO:0030239 36 27 0,000 0,14889716 0,17864552 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,14889716 0,17855238 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,14889716 0,17845933 ! natural killer cell activation GO:0030101 35 27 0,000 0,14889716 0,17836638 ! lipid oxidation GO:0034440 38 27 0,000 0,14889716 0,17827353 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,14889716 0,17818078 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,14889716 0,17808812 ! gene silencing GO:0016458 41 27 0,000 0,14889716 0,17799556 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,15396818 0,18396198 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,15396818 0,18386646 ! phenol metabolic process GO:0018958 44 28 0,000 0,15396818 0,18377105 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,15396818 0,18367573 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,15396818 0,18358051 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,15396818 0,18348539 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,15396818 0,18339037 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,15396818 0,18329545 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,15396818 0,18320063 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,15396818 0,1831059 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,15396818 0,18301127 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,15396818 0,18291674 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,15396818 0,18282231 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,15396818 0,18272797 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,15396818 0,18263373 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,15396818 0,18253959 ! mesoderm formation GO:0001707 46 28 0,000 0,15396818 0,18244555 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,15396818 0,1823516 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,15396818 0,18225775 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,15396818 0,182164 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,15396818 0,18207034 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,15396818 0,18197678 ! placenta development GO:0001890 37 28 0,000 0,15396818 0,18188331 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,15900927 0,18774196 ! regulation of innate immune response GO:0045088 38 29 0,000 0,15900927 0,18764563 ! ovulation cycle process GO:0022602 41 29 0,000 0,15900927 0,1875494 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,15900927 0,18745327 ! protein targeting to membrane GO:0006612 53 29 0,000 0,15900927 0,18735724 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,15900927 0,18726131 ! mismatch repair GO:0006298 34 29 0,000 0,15900927 0,18716547 ! muscle cell development GO:0055001 38 29 0,000 0,15900927 0,18706974 ! formation of primary germ layer GO:0001704 48 29 0,000 0,15900927 0,1869741 ! telencephalon development GO:0021537 52 29 0,000 0,15900927 0,18687855 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,15900927 0,18678311 ! eye morphogenesis GO:0048592 51 29 0,000 0,15900927 0,18668777 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,15900927 0,18659252 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,16402062 0,19237503 ! organic anion transport GO:0015711 51 30 0,000 0,16402062 0,19227698 ! cholesterol transport GO:0030301 46 30 0,000 0,16402062 0,19217903 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,16402062 0,19208118 ! spliceosome assembly GO:0000245 49 30 0,000 0,16402062 0,19198342 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,16402062 0,19188577 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,16402062 0,19178822 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,16402062 0,19169077 ! ceramide metabolic process GO:0006672 43 30 0,000 0,16402062 0,19159341 ! ovulation cycle GO:0042698 43 30 0,000 0,16402062 0,19149616 ! hindbrain development GO:0030902 45 30 0,000 0,16402062 0,191399 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,16402062 0,19130194 ! adult locomotory behavior GO:0008344 47 30 0,000 0,16402062 0,19120498 ! response to heat GO:0009408 41 30 0,000 0,16402062 0,19110812 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,16402062 0,19101136 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,16402062 0,19091469 ! negative regulation of secretion GO:0051048 49 31 0,000 0,16900239 0,19661381 ! glial cell differentiation GO:0010001 55 31 0,000 0,16900239 0,19651441 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,16900239 0,19641511 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,16900239 0,19631591 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,16900239 0,19621681 ! odontogenesis GO:0042476 50 31 0,000 0,16900239 0,19611781 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,16900239 0,19601891 ! metanephros development GO:0001656 58 31 0,000 0,16900239 0,19592011 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,16900239 0,19582141 ! cell fate specification GO:0001708 37 31 0,000 0,16900239 0,19572281 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,16900239 0,19562431 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,16900239 0,19552591 ! RNA modification GO:0009451 40 31 0,000 0,16900239 0,1954276 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,17395476 0,20105324 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,17395476 0,20095226 ! meiosis I GO:0007127 52 32 0,000 0,17395476 0,20085138 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,17395476 0,2007506 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,17395476 0,20064992 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,17395476 0,20054935 GO:0006639|acylglycerol metabolic process, ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,17395476 0,20044887 ! cytokine production GO:0001816 44 32 0,000 0,17395476 0,2003485 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,17395476 0,20024822 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,17395476 0,20014805 ! vesicle localization GO:0051648 47 32 0,000 0,17395476 0,20004797 ! RNA export from nucleus GO:0006405 44 33 0,000 0,17887789 0,20560677 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,17887789 0,20550407 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,17887789 0,20540148 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,17887789 0,20529898 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,17887789 0,20519659 ! sister chromatid segregation GO:0000819 46 33 0,000 0,17887789 0,20509429 ! actomyosin structure organization GO:0031032 43 33 0,000 0,17887789 0,20499211 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,17887789 0,20489002 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,17887789 0,20478803 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,17887789 0,20468615 GO:0042593|glucose homeostasis, ! positive regulation of cell development GO:0010720 54 33 0,000 0,17887789 0,20458436 ! lipid homeostasis GO:0055088 55 33 0,000 0,17887789 0,20448268 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,17887789 0,2043811 ! regulation of proteolysis GO:0030162 50 33 0,000 0,17887789 0,20427962 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,17887789 0,20417824 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,17887789 0,20407696 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,17887789 0,20397578 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,18377197 0,20945269 ! mRNA catabolic process GO:0006402 48 34 0,000 0,18377197 0,20934895 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,18377197 0,20924531 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,18377197 0,20914177 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,18377197 0,20903834 ! feeding behavior GO:0007631 45 34 0,000 0,18377197 0,20893501 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,18377197 0,20883178 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,18377197 0,20872865 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,18377197 0,20862563 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,18377197 0,20852271 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,18377197 0,20841988 ! polyol metabolic process GO:0019751 44 34 0,000 0,18377197 0,20831716 ! aerobic respiration GO:0009060 47 34 0,000 0,18377197 0,20821454 ! embryonic organ development GO:0048568 45 34 0,000 0,18377197 0,20811203 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,18377197 0,20800961 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,18863715 0,21341143 ! Notch signaling pathway GO:0007219 56 35 0,000 0,18863715 0,21330651 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,18863715 0,21320169 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,18863715 0,21309698 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,18863715 0,21299236 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,18863715 0,21288785 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,18863715 0,21278345 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,18863715 0,21267914 ! glycogen metabolic process GO:0005977 48 35 0,000 0,18863715 0,21257494 ! pigment metabolic process GO:0042440 61 35 0,000 0,18863715 0,21247084 ! protein homooligomerization GO:0051260 52 35 0,000 0,18863715 0,21236684 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,19347361 0,21770514 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,19347361 0,21759868 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,19347361 0,21749233 ! organic ether metabolic process GO:0018904 46 36 0,000 0,19347361 0,21738608 ! tissue remodeling GO:0048771 62 36 0,000 0,19347361 0,21727994 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,19347361 0,21717389 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,19347361 0,21706795 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,19347361 0,21696212 ! glucan metabolic process GO:0044042 49 36 0,000 0,19347361 0,21685639 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,19828152 0,22213711 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,19828152 0,22202896 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,19828152 0,22192092 ! learning GO:0007612 67 37 0,000 0,19828152 0,22181298 ! ion transmembrane transport GO:0034220 56 37 0,000 0,19828152 0,22170515 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,19828152 0,22159742 ! regulation of protein secretion GO:0050708 51 37 0,000 0,19828152 0,2214898 ! amino acid activation GO:0043038 52 37 0,000 0,19828152 0,22138228 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,19828152 0,22127486 ! gliogenesis GO:0042063 71 38 0,000 0,20306104 0,22649873 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,20306104 0,22638894 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,20306104 0,22627926 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,20306104 0,22616968 ! phagocytosis GO:0006909 60 38 0,000 0,20306104 0,22606021 ! mesenchymal cell development GO:0014031 64 38 0,000 0,20306104 0,22595084 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,20781234 0,23112591 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,20781234 0,2310142 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,20781234 0,2309026 ! male sex differentiation GO:0046661 53 39 0,000 0,20781234 0,2307911 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,20781234 0,23067972 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,20781234 0,23056844 ! JNK cascade GO:0007254 54 39 0,000 0,20781234 0,23045727 ! cell growth GO:0016049 61 39 0,000 0,20781234 0,2303462 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,21253558 0,23546813 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,21253558 0,23535476 ! regulation of tube size GO:0035150 60 40 0,000 0,21253558 0,2352415 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,21253558 0,23512835 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,21253558 0,2350153 ! peptide metabolic process GO:0006518 56 40 0,000 0,21253558 0,23490237 ! inner ear development GO:0048839 57 40 0,000 0,21253558 0,23478955 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,21253558 0,23467683 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,21253558 0,23456422 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,21253558 0,23445172 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,21253558 0,23433933 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,21723093 0,2394016 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,21723093 0,23928694 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,21723093 0,2391724 ! striated muscle contraction GO:0006941 62 41 0,000 0,21723093 0,23905796 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,21723093 0,23894363 ! biopolymer methylation GO:0043414 62 41 0,000 0,21723093 0,23882942 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,21723093 0,23871531 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,22189855 0,24372811 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,22189855 0,24361177 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,22189855 0,24349555 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,22189855 0,24337943 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,22189855 0,24326343 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,22189855 0,24314753 ! excretion GO:0007588 63 42 0,000 0,22189855 0,24303175 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,22189855 0,24291607 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,22189855 0,24280051 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,22189855 0,24268505 ! regulation of cell shape GO:0008360 78 42 0,000 0,22189855 0,24256971 ! leukocyte migration GO:0050900 60 43 0,000 0,22653861 0,24752437 ! neuromuscular process GO:0050905 79 43 0,000 0,22653861 0,24740683 ! tRNA processing GO:0008033 49 43 0,000 0,22653861 0,24728941 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,22653861 0,2471721 ! vesicle organization GO:0016050 79 43 0,000 0,22653861 0,2470549 ! methylation GO:0032259 64 43 0,000 0,22653861 0,24693782 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,23115125 0,25184646 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,23115125 0,25172722 ! glycolysis GO:0006096 53 44 0,000 0,23115125 0,25160809 ! regulation of ion transport GO:0043269 57 44 0,000 0,23115125 0,25148907 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,23115125 0,25137016 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,23115125 0,25125136 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,23115125 0,25113268 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,23115125 0,25101411 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,23115125 0,25089565 ! RNA catabolic process GO:0006401 64 45 0,000 0,23573666 0,25575203 ! positive regulation of defense response GO:0031349 59 45 0,000 0,23573666 0,25563145 ! regulation of translational initiation GO:0006446 64 45 0,000 0,23573666 0,25551099 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,23573666 0,25539063 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,23573666 0,25527039 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,24029498 0,26008397 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,24029498 0,25996164 ! cell redox homeostasis GO:0045454 63 46 0,000 0,24029498 0,25983942 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,24029498 0,25971731 ! regulation of ossification GO:0030278 71 46 0,000 0,24029498 0,25959532 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,24029498 0,25947345 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,24482637 0,26424244 ! viral infectious cycle GO:0019058 71 47 0,000 0,24482637 0,2641185 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,24482637 0,26399468 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,24482637 0,26387097 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,24482637 0,26374737 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,24482637 0,2636239 ! chloride transport GO:0006821 67 48 0,000 0,24933099 0,26834875 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,24933099 0,26822323 ! response to temperature stimulus GO:0009266 62 48 0,000 0,24933099 0,26809784 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,24933099 0,26797256 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,24933099 0,26784739 ! gastrulation GO:0007369 73 48 0,000 0,24933099 0,26772235 ! heart morphogenesis GO:0003007 65 48 0,000 0,24933099 0,26759742 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,24933099 0,26747261 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,24933099 0,26734791 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,24933099 0,26722333 ! regulation of endocytosis GO:0030100 63 48 0,000 0,24933099 0,26709887 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,24933099 0,26697452 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,25380899 0,27164294 ! sensory perception of smell GO:0007608 61 49 0,000 0,25380899 0,2715166 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,25380899 0,27139037 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,25380899 0,27126426 ! RNA elongation GO:0006354 62 49 0,000 0,25380899 0,27113827 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,25380899 0,27101239 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,25380899 0,27088663 ! regulation of actin filament length GO:0030832 72 50 0,000 0,25826054 0,27550986 ! membrane fusion GO:0006944 80 50 0,000 0,25826054 0,27538213 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,25826054 0,27525452 ! positive regulation of growth GO:0045927 67 50 0,000 0,25826054 0,27512703 ! proton transport GO:0015992 75 50 0,000 0,25826054 0,27499965 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,25826054 0,2748724 ! positive regulation of secretion GO:0051047 71 51 0,000 0,26268579 0,27945297 ! hydrogen transport GO:0006818 77 51 0,000 0,26268579 0,27932377 ! adult behavior GO:0030534 80 51 0,000 0,26268579 0,27919469 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,26268579 0,27906574 ! transition metal ion transport GO:0000041 74 52 0,000 0,26708489 0,28360815 ! regulation of cellular component size GO:0032535 74 52 0,000 0,26708489 0,28347727 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,26708489 0,28334651 ! establishment of organelle localization GO:0051656 85 52 0,000 0,26708489 0,28321588 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,27145799 0,28772045 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,27145799 0,28758792 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,27145799 0,28745552 ! kidney development GO:0001822 90 53 0,000 0,27145799 0,28732323 ! single fertilization GO:0007338 59 53 0,000 0,27145799 0,28719107 ! amino acid transport GO:0006865 84 54 0,000 0,27580525 0,29165613 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,27580525 0,29152209 ! regulation of mitosis GO:0007088 84 54 0,000 0,27580525 0,29138818 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,27580525 0,2912544 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,27580525 0,29112073 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,27580525 0,29098719 ! exocytosis GO:0006887 74 55 0,000 0,28012682 0,29541113 ! mesoderm development GO:0007498 76 55 0,000 0,28012682 0,29527574 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,28012682 0,29514048 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,28012682 0,29500535 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,28442284 0,29939246 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,28442284 0,2992555 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,28869347 0,30360996 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,28869347 0,3034712 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,28869347 0,30333256 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,28869347 0,30319406 ! camera-type eye development GO:0043010 88 57 0,000 0,28869347 0,30305567 ! secondary metabolic process GO:0019748 84 57 0,000 0,28869347 0,30291742 ! viral reproductive process GO:0022415 87 58 0,000 0,29293886 0,30723182 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,29293886 0,30709178 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,29293886 0,30695188 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,29715915 0,31123226 ! activation of MAPK activity GO:0000187 84 59 0,000 0,29715915 0,3110906 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,29715915 0,31094907 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,29715915 0,31080766 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,30135449 0,31505242 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,30135449 0,31490928 ! regulation of heart contraction GO:0008016 91 60 0,000 0,30135449 0,31476627 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,30135449 0,31462339 ! fertilization GO:0009566 68 60 0,000 0,30135449 0,31448064 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,30552503 0,31868824 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,30552503 0,31854378 ! urogenital system development GO:0001655 101 61 0,000 0,30552503 0,31839944 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,30552503 0,31825524 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,30552503 0,31811117 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,30552503 0,31796723 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,30967091 0,32213618 ! neurotransmitter transport GO:0006836 81 62 0,000 0,30967091 0,32199055 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,30967091 0,32184505 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,30967091 0,32169968 ! organelle localization GO:0051640 96 62 0,000 0,30967091 0,32155445 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,31379228 0,32568693 ! viral reproduction GO:0016032 92 63 0,000 0,31379228 0,32554003 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,31788928 0,32964172 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,31788928 0,32949317 ! hexose catabolic process GO:0019320 82 64 0,000 0,31788928 0,32934475 ! adaptive immune response GO:0002250 94 64 0,000 0,31788928 0,32919646 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! defense response to bacterium GO:0042742 73 65 0,000 0,32196205 0,33326405 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,32196205 0,33311413 ! activation of immune response GO:0002253 83 65 0,000 0,32196205 0,33296435 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,32601073 0,33699986 ! antigen processing and presentation GO:0019882 96 66 0,000 0,32601073 0,33684847 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,32601073 0,33669721 ! regulation of immune effector process GO:0002697 101 66 0,000 0,32601073 0,33654609 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,33003547 0,34054804 ! acute inflammatory response GO:0002526 92 68 0,000 0,33403641 0,34452186 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,33403641 0,34436743 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,33403641 0,34421315 ! rhythmic process GO:0048511 105 68 0,000 0,33403641 0,344059 ! inorganic anion transport GO:0015698 93 68 0,000 0,33403641 0,34390499 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,33801368 0,34784406 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,33801368 0,34768849 ! humoral immune response GO:0006959 86 70 0,000 0,34196743 0,35159816 ! eye development GO:0001654 111 70 0,000 0,34196743 0,35144106 ! amine transport GO:0015837 101 70 0,000 0,34196743 0,35128409 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,34196743 0,35112727 ! muscle cell differentiation GO:0042692 104 71 0,000 0,34589779 0,35500442 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,34589779 0,35484608 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,34589779 0,35468788 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,34589779 0,35452982 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,34980489 0,35837472 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,34980489 0,35821516 ! regulation of blood pressure GO:0008217 107 73 0,000 0,35368888 0,36203135 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,35368888 0,3618703 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,3575499 0,36565796 ! digestion GO:0007586 97 74 0,000 0,3575499 0,36549545 ! blood coagulation GO:0007596 116 75 0,000 0,36138806 0,3692548 GO:0050817|coagulation, ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,36138806 0,36909083 ! tRNA metabolic process GO:0006399 95 76 0,000 0,36520352 0,37282206 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,36520352 0,37265665 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,3689964 0,37635996 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,3689964 0,37619314 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,3689964 0,37602646 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,37276683 0,37970049 ! cellular respiration GO:0045333 107 79 0,000 0,37651495 0,38334855 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,37651495 0,38317893 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,37651495 0,38300946 ! chromatin assembly GO:0031497 102 80 0,000 0,38024088 0,38662866 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,38024088 0,38645781 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,38024088 0,38628712 ! forebrain development GO:0030900 131 80 0,000 0,38024088 0,38611657 ! hemostasis GO:0007599 125 81 0,000 0,38394476 0,38970563 ! regulation of neurological system process GO:0031644 122 81 0,000 0,38394476 0,38953373 ! vitamin metabolic process GO:0006766 103 81 0,000 0,38394476 0,38936197 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,39128688 0,3966328 ! regulation of defense response GO:0031347 117 84 0,000 0,39492538 0,40014466 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,39492538 0,39996846 ! sterol metabolic process GO:0016125 120 84 0,000 0,39492538 0,39979242 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,39854233 0,40327645 ! rRNA metabolic process GO:0016072 107 85 0,000 0,39854233 0,4030991 GO:0006364|rRNA processing, ! nucleosome organization GO:0034728 114 87 0,000 0,40571212 0,4101705 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,40571212 0,40999028 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,40571212 0,40981022 ! female pregnancy GO:0007565 130 87 0,000 0,40571212 0,40963032 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,40926521 0,41303641 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,40926521 0,41285525 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,41279725 0,41623572 ! hormone metabolic process GO:0042445 121 90 0,000 0,41630838 0,41959215 ! ATP metabolic process GO:0046034 137 91 0,000 0,41979872 0,42292469 ! positive regulation of immune response GO:0050778 121 92 0,000 0,42326839 0,42623349 ! sulfur metabolic process GO:0006790 118 92 0,000 0,42326839 0,42604695 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,4267175 0,42933082 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,4267175 0,42914309 ! electron transport chain GO:0022900 123 94 0,000 0,43014618 0,43240219 ! response to oxidative stress GO:0006979 141 94 0,000 0,43014618 0,43221329 ! carboxylic acid transport GO:0046942 147 95 0,000 0,43355456 0,43544781 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,43694274 0,43865923 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,43694274 0,43846784 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,44031085 0,44165502 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,44698732 0,44815642 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,44698732 0,44796115 ! regulation of translation GO:0006417 151 100 0,000 0,45029592 0,4510804 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,45029592 0,45088403 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,45029592 0,45068782 ! divalent metal ion transport GO:0070838 171 100 0,000 0,45029592 0,45049178 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,45029592 0,45029592