pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6367-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycine biosynthetic process GO:0006545 7 5 3,000 1,601E-09 3,852E-06 ! response to UV GO:0009411 104 53 5,000 1,069E-07 1,286E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 1,667E-07 1,337E-04 ! serine family amino acid biosynthetic process GO:0009070 17 13 3,000 2,229E-07 1,341E-04 ! negative regulation of DNA metabolic process GO:0051053 61 35 4,000 3,905E-07 1,879E-04 ! glycine metabolic process GO:0006544 28 17 3,000 7,322E-07 2,936E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 1,127E-06 3,872E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,42E-06 4,271E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,588E-06 4,245E-04 ! collagen catabolic process GO:0030574 28 21 3,000 1,817E-06 4,372E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 2,654E-06 5,804E-04 ! negative regulation of DNA replication GO:0008156 42 25 3,000 3,79E-06 7,598E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 3,946E-06 7,303E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 4,232E-06 7,274E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 4,232E-06 6,789E-04 ! multicellular organismal catabolic process GO:0044243 36 27 3,000 5,223E-06 7,854E-04 ! cell junction assembly GO:0034329 78 30 3,000 8,075E-06 1,143E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 9,012E-06 1,205E-03 ! collagen metabolic process GO:0032963 45 31 3,000 9,24E-06 1,17E-03 ! serine family amino acid metabolic process GO:0009069 49 31 3,000 9,24E-06 1,112E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 3,000 1,348E-05 1,545E-03 ! cell junction organization GO:0034330 86 36 3,000 1,701E-05 1,861E-03 ! response to X-ray GO:0010165 25 13 2,000 2,128E-05 2,226E-03 ! mammary gland development GO:0030879 86 39 3,000 2,352E-05 2,358E-03 ! multicellular organismal metabolic process GO:0044236 57 40 3,000 2,605E-05 2,507E-03 ! response to gamma radiation GO:0010332 28 14 2,000 2,7E-05 2,498E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 2,7E-05 2,406E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 4,127E-05 3,547E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 5,401E-05 4,481E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 5,676E-05 4,552E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 5,977E-05 4,639E-03 ! interphase GO:0051325 213 98 4,000 6,585E-05 4,951E-03 ! cellular amino acid biosynthetic process GO:0008652 75 51 3,000 6,868E-05 5,008E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 7,075E-05 5,007E-03 ! cell cycle arrest GO:0007050 213 100 4,000 7,25E-05 4,984E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 8,297E-05 5,545E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 9,251E-05 6,015E-03 ! hindlimb morphogenesis GO:0035137 43 21 2,000 9,65E-05 6,11E-03 ! cell aging GO:0007569 44 21 2,000 9,65E-05 5,953E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 9,929E-05 5,972E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,114E-04 6,537E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 1,114E-04 6,381E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,648E-04 9,221E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,648E-04 9,012E-03 ! embryonic limb morphogenesis GO:0030326 125 65 3,000 1,777E-04 9,499E-03 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of helicase activity GO:0051096 11 5 1,000 1,805E-04 9,442E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,805E-04 9,241E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,805E-04 9,049E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,805E-04 8,864E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,805E-04 8,687E-03 ! microvillus organization GO:0032528 7 5 1,000 1,805E-04 8,516E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,805E-04 8,352E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 1,805E-04 8,195E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,805E-04 8,043E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,805E-04 7,897E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,805E-04 7,756E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,857E-04 7,839E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,083E-04 8,64E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,083E-04 8,494E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 2,325E-04 9,325E-03 ! appendage morphogenesis GO:0035107 135 70 3,000 2,367E-04 9,335E-03 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 3,000 2,5E-04 9,701E-03 GO:0060173|limb development, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 2,586E-04 9,875E-03 ! male meiosis GO:0007140 7 6 1,000 2,7E-04 0,01015101 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,7E-04 9,995E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 2,7E-04 9,843E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 2,7E-04 9,696E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,7E-04 9,554E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 3,247E-04 0,01132107 ! response to ionizing radiation GO:0010212 65 32 2,000 3,477E-04 0,01195112 ! response to mechanical stimulus GO:0009612 57 32 2,000 3,477E-04 0,0117828 ! BMP signaling pathway GO:0030509 64 32 2,000 3,477E-04 0,01161915 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 3,77E-04 0,01242434 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,77E-04 0,01225644 ! neuron adhesion GO:0007158 12 7 1,000 3,77E-04 0,01209302 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,77E-04 0,0119339 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,77E-04 0,01177892 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 3,77E-04 0,0116279 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 3,77E-04 0,01148072 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 3,77E-04 0,01133721 ! centrosome duplication GO:0051298 13 7 1,000 3,77E-04 0,01119724 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,77E-04 0,01106069 ! B cell lineage commitment GO:0002326 21 7 1,000 3,77E-04 0,01092743 ! transcription from RNA polymerase I promoter GO:0006360 13 7 1,000 3,77E-04 0,01079734 ! T cell lineage commitment GO:0002360 16 7 1,000 3,77E-04 0,01067031 ! transcription termination GO:0006353 13 7 1,000 3,77E-04 0,01054624 ! response to tumor cell GO:0002347 13 7 1,000 3,77E-04 0,01042502 ! axonal fasciculation GO:0007413 18 7 1,000 3,77E-04 0,01030655 ! negative regulation of protein transport GO:0051224 69 33 2,000 3,813E-04 0,01030746 ! response to hypoxia GO:0001666 171 81 3,000 4,141E-04 0,01107134 ! response to oxygen levels GO:0070482 176 83 3,000 4,544E-04 0,01201457 ! neural tube formation GO:0001841 67 35 2,000 4,545E-04 0,01188707 ! negative regulation of growth GO:0045926 155 84 3,000 4,756E-04 0,01230338 ! one-carbon metabolic process GO:0006730 154 85 3,000 4,974E-04 0,01273158 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,012E-04 0,01269377 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,012E-04 0,01256154 ! ER overload response GO:0006983 12 8 1,000 5,012E-04 0,01243204 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 5,012E-04 0,01230518 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,012E-04 0,01218089 ! blastocyst growth GO:0001832 19 8 1,000 5,012E-04 0,01205908 ! amine biosynthetic process GO:0009309 138 86 3,000 5,2E-04 0,01238632 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,362E-04 0,01264912 ! gland development GO:0048732 206 88 3,000 5,672E-04 0,01324981 ! embryonic epithelial tube formation GO:0001838 72 38 2,000 5,804E-04 0,01342723 ! keratinocyte proliferation GO:0043616 14 9 1,000 6,426E-04 0,01472478 ! middle ear morphogenesis GO:0042474 14 9 1,000 6,426E-04 0,01458587 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 6,426E-04 0,01444955 ! receptor clustering GO:0043113 18 9 1,000 6,426E-04 0,01431576 ! motor axon guidance GO:0008045 16 9 1,000 6,426E-04 0,01418443 ! regulation of telomere maintenance GO:0032204 14 9 1,000 6,426E-04 0,01405548 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 6,986E-04 0,01514288 ! T cell differentiation GO:0030217 81 41 2,000 7,266E-04 0,01560827 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 7,8E-04 0,01660825 ! neuron migration GO:0001764 79 42 2,000 7,8E-04 0,01646256 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,01E-04 0,01675832 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,01E-04 0,01661385 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 8,01E-04 0,01647185 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 8,01E-04 0,01633226 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 8,01E-04 0,01619502 ! multicellular organism growth GO:0035264 18 10 1,000 8,01E-04 0,01606006 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 8,01E-04 0,01592733 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 8,01E-04 0,01579678 ! oocyte development GO:0048599 17 10 1,000 8,01E-04 0,01566835 ! localization within membrane GO:0051668 20 10 1,000 8,01E-04 0,01554199 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 8,359E-04 0,01608962 ! neural tube development GO:0021915 77 43 2,000 8,359E-04 0,01596192 ! double-strand break repair GO:0006302 81 44 2,000 8,943E-04 0,01694205 ! negative regulation of muscle development GO:0048635 20 11 1,000 9,763E-04 0,01835055 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 9,763E-04 0,0182083 ! detection of mechanical stimulus GO:0050982 22 11 1,000 9,763E-04 0,01806823 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 9,763E-04 0,01793031 ! regulation of intracellular pH GO:0051453 19 11 1,000 9,763E-04 0,01779447 ! oocyte differentiation GO:0009994 18 11 1,000 9,763E-04 0,01766068 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,019E-03 0,01828979 ! pigmentation GO:0043473 100 46 2,000 1,019E-03 0,01815431 ! response to insulin stimulus GO:0032868 95 46 2,000 1,019E-03 0,01802082 ! cellular component disassembly GO:0022411 86 48 2,000 1,153E-03 0,02025625 ! morphogenesis of embryonic epithelium GO:0016331 91 48 2,000 1,153E-03 0,02010947 ! activation of caspase activity GO:0006919 84 48 2,000 1,153E-03 0,0199648 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,153E-03 0,01982219 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,168E-03 0,01993435 ! protein complex disassembly GO:0043241 27 12 1,000 1,168E-03 0,01979397 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,168E-03 0,01965555 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,168E-03 0,01951905 ! focal adhesion formation GO:0048041 35 12 1,000 1,168E-03 0,01938444 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,168E-03 0,01925167 GO:0006509|membrane protein ectodomain proteolysis, ! histone acetylation GO:0016573 26 12 1,000 1,168E-03 0,0191207 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,168E-03 0,01899151 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,168E-03 0,01886405 GO:0042130|negative regulation of T cell proliferation, ! DNA-dependent DNA replication GO:0006261 74 49 2,000 1,225E-03 0,01964596 ! response to estrogen stimulus GO:0043627 93 51 2,000 1,376E-03 0,02192211 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,376E-03 0,02177789 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,376E-03 0,02163555 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,377E-03 0,0215096 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 22 13 1,000 1,377E-03 0,02137083 ! cell-cell junction assembly GO:0007043 27 13 1,000 1,377E-03 0,02123384 ! regulation of cellular pH GO:0030641 22 13 1,000 1,377E-03 0,02109859 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,377E-03 0,02096506 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,377E-03 0,0208332 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 1,538E-03 0,0231285 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,602E-03 0,02393623 ! regulation of S phase GO:0033261 23 14 1,000 1,602E-03 0,02378848 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,602E-03 0,02364254 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,602E-03 0,02349837 ! bone mineralization GO:0030282 17 14 1,000 1,602E-03 0,02335596 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,712E-03 0,02481065 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 1,712E-03 0,02466208 ! nucleotide-excision repair GO:0006289 83 56 2,000 1,803E-03 0,02582245 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 1,843E-03 0,02623765 ! heterophilic cell adhesion GO:0007157 39 15 1,000 1,843E-03 0,02608331 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,843E-03 0,02593078 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,843E-03 0,02578002 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,897E-03 0,02638702 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 2,1E-03 0,02904269 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 2,1E-03 0,02887674 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,1E-03 0,02871266 ! DNA replication initiation GO:0006270 27 16 1,000 2,1E-03 0,02855045 ! neuron recognition GO:0008038 35 16 1,000 2,1E-03 0,02839005 ! biomineral formation GO:0031214 20 16 1,000 2,1E-03 0,02823145 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,1E-03 0,0280746 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA damage response, signal transduction GO:0042770 128 60 2,000 2,198E-03 0,02922207 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,198E-03 0,02906151 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,305E-03 0,03030331 ! signal complex assembly GO:0007172 41 17 1,000 2,374E-03 0,03103909 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,374E-03 0,03087131 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,374E-03 0,03070533 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,374E-03 0,03054113 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,374E-03 0,03037868 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,663E-03 0,03390009 ! memory GO:0007613 31 18 1,000 2,663E-03 0,03372166 ! centrosome cycle GO:0007098 25 18 1,000 2,663E-03 0,03354511 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 2,663E-03 0,0333704 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 2,663E-03 0,03319749 ! actin filament organization GO:0007015 148 66 2,000 2,885E-03 0,03578458 ! extracellular matrix organization GO:0030198 133 66 2,000 2,885E-03 0,03560107 ! developmental maturation GO:0021700 116 66 2,000 2,885E-03 0,03541943 ! lipid phosphorylation GO:0046834 35 19 1,000 2,968E-03 0,03624806 ! forelimb morphogenesis GO:0035136 32 19 1,000 2,968E-03 0,03606499 ! pigmentation during development GO:0048066 41 19 1,000 2,968E-03 0,03588376 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,968E-03 0,03570434 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 2,968E-03 0,03552671 ! neuromuscular junction development GO:0007528 34 19 1,000 2,968E-03 0,03535083 ! protein export from nucleus GO:0006611 36 19 1,000 2,968E-03 0,03517669 ! cell-cell junction organization GO:0045216 35 19 1,000 2,968E-03 0,03500426 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 2,968E-03 0,0348335 ! negative regulation of cell growth GO:0030308 132 67 2,000 3,011E-03 0,03517033 ! cell cycle checkpoint GO:0000075 137 69 2,000 3,273E-03 0,03804323 ! negative regulation of cell size GO:0045792 134 69 2,000 3,273E-03 0,03786033 ! protein import into nucleus, docking GO:0000059 41 20 1,000 3,288E-03 0,03785701 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 3,288E-03 0,03767674 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,288E-03 0,03749818 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,288E-03 0,0373213 ! response to alkaloid GO:0043279 38 20 1,000 3,288E-03 0,03714608 ! pancreas development GO:0031016 35 20 1,000 3,288E-03 0,0369725 ! cellular response to starvation GO:0009267 33 20 1,000 3,288E-03 0,03680054 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,288E-03 0,03663017 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,288E-03 0,03646136 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,288E-03 0,03629411 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 3,624E-03 0,03981977 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,624E-03 0,03963877 ! oogenesis GO:0048477 36 21 1,000 3,624E-03 0,03945941 ! collagen fibril organization GO:0030199 59 21 1,000 3,624E-03 0,03928167 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 3,624E-03 0,03910552 ! regulation of caspase activity GO:0043281 122 72 2,000 3,691E-03 0,03964722 ! learning or memory GO:0007611 147 73 2,000 3,837E-03 0,04103514 ! axon guidance GO:0007411 139 73 2,000 3,837E-03 0,04085357 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,976E-03 0,04214001 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,976E-03 0,04195519 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,976E-03 0,04177198 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 3,976E-03 0,04159036 ! protein stabilization GO:0050821 39 22 1,000 3,976E-03 0,04141032 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 3,976E-03 0,04123182 ! glutamate signaling pathway GO:0007215 41 22 1,000 3,976E-03 0,04105486 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,976E-03 0,04087941 ! regulation of transcription factor activity GO:0051090 126 74 2,000 3,987E-03 0,04082226 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 3,987E-03 0,04064929 ! lymphocyte differentiation GO:0030098 167 75 2,000 4,14E-03 0,04203381 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,342E-03 0,04389727 ! leukocyte adhesion GO:0007159 50 23 1,000 4,342E-03 0,0437136 ! regulation of DNA recombination GO:0000018 48 23 1,000 4,342E-03 0,04353146 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,342E-03 0,04335083 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,342E-03 0,04317169 ! negative regulation of catabolic process GO:0009895 50 23 1,000 4,342E-03 0,04299403 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 4,622E-03 0,04557243 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 4,724E-03 0,04638982 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,724E-03 0,04620124 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 4,724E-03 0,04601419 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 4,724E-03 0,04582865 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,724E-03 0,0456446 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,724E-03 0,04546202 ! protein tetramerization GO:0051262 52 24 1,000 4,724E-03 0,0452809 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 4,789E-03 0,0457256 ! regulation of peptidase activity GO:0052547 134 79 2,000 4,789E-03 0,04554487 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 4,789E-03 0,04536556 ! protein import into nucleus GO:0006606 158 80 2,000 4,96E-03 0,04680301 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,12E-03 0,04812238 ! myelination GO:0042552 45 25 1,000 5,12E-03 0,04793514 ! receptor metabolic process GO:0043112 46 25 1,000 5,12E-03 0,04774934 ! response to starvation GO:0042594 42 25 1,000 5,12E-03 0,04756498 ! negative regulation of cell development GO:0010721 73 25 1,000 5,12E-03 0,04738204 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 5,12E-03 0,0472005 ! immunoglobulin production GO:0002377 55 25 1,000 5,12E-03 0,04702035 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,12E-03 0,04684156 ! neural tube closure GO:0001843 49 25 1,000 5,12E-03 0,04666413 GO:0060606|tube closure, ! T cell activation GO:0042110 168 81 2,000 5,135E-03 0,04662442 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 5,135E-03 0,04644915 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 2,000 5,135E-03 0,04627518 ! regulation of neuron differentiation GO:0045664 167 81 2,000 5,135E-03 0,04610251 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 5,314E-03 0,04752795 ! tube lumen formation GO:0035148 50 26 1,000 5,531E-03 0,0492915 ! macromolecular complex disassembly GO:0032984 53 26 1,000 5,531E-03 0,04910961 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 5,531E-03 0,04892906 ! microtubule organizing center organization GO:0031023 39 26 1,000 5,531E-03 0,04874984 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 5,531E-03 0,04857192 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,531E-03 0,04839529 GO:0045936|negative regulation of phosphate metabolic process, ! somatic diversification of immune receptors GO:0002200 56 26 1,000 5,531E-03 0,04821995 ! blastocyst development GO:0001824 49 26 1,000 5,531E-03 0,04804587 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 5,682E-03 0,04917567 ! negative regulation of transport GO:0051051 153 84 2,000 5,682E-03 0,04899942 ! protein amino acid acylation GO:0043543 55 27 1,000 5,957E-03 0,0511904 ! fat cell differentiation GO:0045444 50 27 1,000 5,957E-03 0,05100823 ! mitochondrial membrane organization GO:0007006 57 27 1,000 5,957E-03 0,05082735 ! primary neural tube formation GO:0014020 51 27 1,000 5,957E-03 0,05064774 ! base-excision repair GO:0006284 41 27 1,000 5,957E-03 0,05046941 ! regulation of chromosome organization GO:0033044 42 27 1,000 5,957E-03 0,05029232 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 5,957E-03 0,05011647 ! tube morphogenesis GO:0035239 176 86 2,000 6,065E-03 0,05084533 ! mitochondrion organization GO:0007005 148 86 2,000 6,065E-03 0,05066879 ! protein localization in nucleus GO:0034504 176 87 2,000 6,262E-03 0,05213528 ! regulation of protein transport GO:0051223 154 87 2,000 6,262E-03 0,0519555 GO:0070201|regulation of establishment of protein localization, ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 6,398E-03 0,05289634 ! regulation of DNA binding GO:0051101 155 88 2,000 6,463E-03 0,05325585 ! regulation of pH GO:0006885 43 29 1,000 6,852E-03 0,0562695 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 6,852E-03 0,05607811 ! response to organic cyclic substance GO:0014070 55 29 1,000 6,852E-03 0,05588801 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 6,852E-03 0,0556992 ! tissue homeostasis GO:0001894 48 29 1,000 6,852E-03 0,05551166 GO:0048871|multicellular organismal homeostasis, ! ossification GO:0001503 188 90 2,000 6,877E-03 0,05552178 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 6,877E-03 0,05533608 ! regulation of cell cycle process GO:0010564 149 90 2,000 6,877E-03 0,05515163 ! bone development GO:0060348 189 91 2,000 7,089E-03 0,05666691 ! ensheathment of neurons GO:0007272 57 30 1,000 7,321E-03 0,05832909 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 7,321E-03 0,05813658 ! regulation of B cell activation GO:0050864 50 30 1,000 7,321E-03 0,05794534 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 7,526E-03 0,05936776 ! transcription initiation GO:0006352 153 94 2,000 7,75E-03 0,06093602 ! iron ion homeostasis GO:0055072 54 31 1,000 7,805E-03 0,06116543 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 7,805E-03 0,06096684 GO:0043433|negative regulation of transcription factor activity, ! leukocyte differentiation GO:0002521 202 96 2,000 8,21E-03 0,06392621 ! mRNA transport GO:0051028 169 96 2,000 8,21E-03 0,06371999 ! spindle organization GO:0007051 46 32 1,000 8,302E-03 0,06422466 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,302E-03 0,06401881 ! peripheral nervous system development GO:0007422 64 32 1,000 8,302E-03 0,06381428 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,302E-03 0,06361105 ! protein ubiquitination GO:0016567 217 97 2,000 8,446E-03 0,06451045 ! regulation of protein localization GO:0032880 176 97 2,000 8,446E-03 0,0643063 ! DNA damage checkpoint GO:0000077 71 33 1,000 8,813E-03 0,06688745 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 8,813E-03 0,06667711 ! skeletal muscle tissue development GO:0007519 186 99 2,000 8,93E-03 0,06734973 GO:0060538|skeletal muscle organ development, ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 9,337E-03 0,07020575 ! mismatch repair GO:0006298 46 34 1,000 9,337E-03 0,06998704 ! regulation of muscle development GO:0048634 70 35 1,000 9,876E-03 0,07379232 ! female gonad development GO:0008585 58 35 1,000 9,876E-03 0,07356386 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 9,876E-03 0,07333681 ! calcium-mediated signaling GO:0019722 62 35 1,000 9,876E-03 0,07311116 ! regulation of microtubule-based process GO:0032886 78 35 1,000 9,876E-03 0,07288689 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01042763 0,07672441 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01042763 0,07649049 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01042763 0,076258 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01042763 0,07602691 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01099285 0,07990576 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01099285 0,07966508 ! regulation of protein stability GO:0031647 73 37 1,000 0,01099285 0,07942584 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01157132 0,0833551 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01157132 0,08310628 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01157132 0,08285894 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01157132 0,08261307 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 0,01216292 0,08657983 ! segmentation GO:0035282 67 39 1,000 0,01216292 0,08632443 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01216292 0,08607054 ! negative regulation of binding GO:0051100 72 40 1,000 0,01276752 0,09008402 ! maintenance of protein location GO:0045185 91 40 1,000 0,01276752 0,08982062 ! cytokinesis GO:0000910 72 40 1,000 0,01276752 0,08955875 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,013385 0,09361721 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,013385 0,09334585 ! female gamete generation GO:0007292 61 41 1,000 0,013385 0,09307607 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,013385 0,09280784 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01401525 0,09689856 GO:0090047|positive regulation of transcription regulator activity, ! glucose transport GO:0015758 65 43 1,000 0,01465815 0,10105302 ! hexose transport GO:0008645 67 44 1,000 0,01531357 0,10526986 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01531357 0,10496994 ! B cell differentiation GO:0030183 107 44 1,000 0,01531357 0,10467173 ! developmental growth GO:0048589 82 44 1,000 0,01531357 0,10437521 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01531357 0,10408037 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,0159814 0,10831339 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01666153 0,11260572 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01666153 0,1122903 ! response to calcium ion GO:0051592 81 47 1,000 0,01735383 0,11662938 ! endosome transport GO:0016197 108 47 1,000 0,01735383 0,11630451 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01735383 0,11598144 ! mitochondrial transport GO:0006839 82 48 1,000 0,0180582 0,12035464 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0180582 0,12002217 ! endocrine system development GO:0035270 104 49 1,000 0,01877451 0,12443933 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01877451 0,12409746 ! regulation of action potential GO:0001508 95 49 1,000 0,01877451 0,12375747 ! histone modification GO:0016570 91 50 1,000 0,01950266 0,12820602 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01950266 0,12785668 ! positive regulation of binding GO:0051099 78 51 1,000 0,02024253 0,13234655 ! chromatin remodeling GO:0006338 109 51 1,000 0,02024253 0,13198789 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02099401 0,13651782 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02099401 0,13614985 ! cartilage development GO:0051216 90 52 1,000 0,02099401 0,13578386 ! synapse organization GO:0050808 85 52 1,000 0,02099401 0,13541982 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02123519 0,13660928 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02123519 0,13624499 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02123519 0,13588264 ! neuron fate determination GO:0048664 7 5 0,000 0,02123519 0,13552221 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02123519 0,13516368 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02123519 0,13480705 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02123519 0,13445229 ! polyol transport GO:0015791 12 5 0,000 0,02123519 0,1340994 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02123519 0,13374836 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02123519 0,13339914 ! response to superoxide GO:0000303 10 5 0,000 0,02123519 0,13305175 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02123519 0,13270616 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02123519 0,13236236 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02123519 0,13202034 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02123519 0,13168008 ! female meiosis GO:0007143 7 5 0,000 0,02123519 0,13134157 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02123519 0,1310048 ! cobalt ion transport GO:0006824 11 5 0,000 0,02123519 0,13066975 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02123519 0,13033641 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02123519 0,13000476 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02123519 0,1296748 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02123519 0,12934651 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02123519 0,12901988 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02123519 0,12869489 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02123519 0,12837154 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02123519 0,1280498 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02123519 0,12772968 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02123519 0,12741115 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02123519 0,12709421 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02123519 0,12677884 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02123519 0,12646503 ! negative chemotaxis GO:0050919 14 5 0,000 0,02123519 0,12615277 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02123519 0,12584205 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02123519 0,12553285 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02123519 0,12522518 ! behavioral response to pain GO:0048266 9 5 0,000 0,02123519 0,124919 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02123519 0,12461432 ! Notch receptor processing GO:0007220 8 5 0,000 0,02123519 0,12431112 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02123519 0,1240094 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02123519 0,12370913 ! micturition GO:0060073 9 5 0,000 0,02123519 0,12341032 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02123519 0,12311294 ! copulation GO:0007620 9 5 0,000 0,02123519 0,122817 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02123519 0,12252247 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02123519 0,12222936 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02123519 0,12193764 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02123519 0,12164731 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02123519 0,12135836 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02123519 0,12107079 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02123519 0,12078457 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02123519 0,1204997 ! grooming behavior GO:0007625 6 5 0,000 0,02123519 0,12021617 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02123519 0,11993397 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02123519 0,1196531 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02123519 0,11937353 ! response to protozoan GO:0001562 10 5 0,000 0,02123519 0,11909527 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02123519 0,11881831 ! lymph vessel development GO:0001945 10 5 0,000 0,02123519 0,11854263 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02123519 0,11826822 ! endochondral ossification GO:0001958 16 5 0,000 0,02123519 0,11799508 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02123519 0,11772321 ! parathyroid gland development GO:0060017 13 5 0,000 0,02123519 0,11745258 ! anagen GO:0042640 6 5 0,000 0,02123519 0,11718319 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02123519 0,11691504 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02123519 0,11664811 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02123519 0,1163824 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02123519 0,11611789 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02123519 0,11585458 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02123519 0,11559247 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02123519 0,11533154 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02123519 0,11507178 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02123519 0,11481319 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02123519 0,11455577 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02123519 0,11429949 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02123519 0,11404436 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02123519 0,11379036 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02123519 0,11353749 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02123519 0,11328575 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02123519 0,11303511 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02123519 0,11278559 ! histidine catabolic process GO:0006548 6 5 0,000 0,02123519 0,11253716 GO:0009077|histidine family amino acid catabolic process, ! valine metabolic process GO:0006573 10 5 0,000 0,02123519 0,11228983 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02123519 0,11204358 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02123519 0,11179841 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02123519 0,1115543 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02123519 0,11131127 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02123519 0,11106929 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02123519 0,11082835 ! polyol catabolic process GO:0046174 7 5 0,000 0,02123519 0,11058847 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02123519 0,11034961 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02123519 0,11011179 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02123519 0,10987499 ! muscle cell migration GO:0014812 8 5 0,000 0,02123519 0,10963921 ! mitochondrial fission GO:0000266 8 5 0,000 0,02123519 0,10940444 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02123519 0,10917067 ! mRNA transcription GO:0009299 9 5 0,000 0,02123519 0,10893789 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02123519 0,10870611 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02123519 0,10847531 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02123519 0,10824549 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02123519 0,10801664 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02123519 0,10778876 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02123519 0,10756184 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02123519 0,10733586 ! response to food GO:0032094 6 5 0,000 0,02123519 0,10711084 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02123519 0,10688676 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02123519 0,10666362 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02123519 0,1064414 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02123519 0,10622011 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02123519 0,10599973 ! forebrain neuron development GO:0021884 13 5 0,000 0,02123519 0,10578027 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02123519 0,10556172 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02123519 0,10534407 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02123519 0,10512731 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02123519 0,10491144 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02123519 0,10469646 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02123519 0,10448236 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02123519 0,10426913 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02123519 0,10405677 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02123519 0,10384527 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02123519 0,10363463 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02123519 0,10342484 ! basic amino acid transport GO:0015802 11 5 0,000 0,02123519 0,1032159 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02123519 0,10300781 ! depyrimidination GO:0045008 10 5 0,000 0,02123519 0,10280055 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02123519 0,10259412 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02123519 0,10238852 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02123519 0,10218374 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02123519 0,10197978 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02123519 0,10177664 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02123519 0,1015743 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02123519 0,10137276 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02123519 0,10117202 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02123519 0,10097208 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02123519 0,10077292 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02123519 0,10057455 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02123519 0,10037696 ! response to arsenic GO:0046685 10 5 0,000 0,02123519 0,10018014 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02123519 0,09998409 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02123519 0,09978881 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02123519 0,09959429 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02123519 0,09940053 ! response to cadmium ion GO:0046686 7 5 0,000 0,02123519 0,09920752 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02123519 0,09901526 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02123519 0,09882374 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02123519 0,09863296 ! decidualization GO:0046697 11 5 0,000 0,02123519 0,09844291 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02123519 0,0982536 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02123519 0,09806501 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02123519 0,09787715 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02123519 0,09769 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02123519 0,09750357 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02123519 0,09731785 ! neural tube patterning GO:0021532 7 5 0,000 0,02123519 0,09713284 ! embryonic cleavage GO:0040016 6 5 0,000 0,02123519 0,09694852 ! peroxisome fission GO:0016559 5 5 0,000 0,02123519 0,09676491 ! histone demethylation GO:0016577 10 5 0,000 0,02123519 0,09658199 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02123519 0,09639976 ! mitotic recombination GO:0006312 9 5 0,000 0,02123519 0,09621821 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02123519 0,09603735 ! metaphase plate congression GO:0051310 7 5 0,000 0,02123519 0,09585717 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02123519 0,09567766 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02123519 0,09549883 ! enteric nervous system development GO:0048484 8 5 0,000 0,02123519 0,09532066 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02123519 0,09514315 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02123519 0,0949663 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02123519 0,09479011 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02123519 0,09461458 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02123519 0,09443969 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02123519 0,09426545 ! plasminogen activation GO:0031639 5 5 0,000 0,02123519 0,09409184 ! B cell homeostasis GO:0001782 13 5 0,000 0,02123519 0,09391888 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02123519 0,09374655 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02123519 0,09357486 ! metaphase GO:0051323 8 5 0,000 0,02123519 0,09340379 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02123519 0,09323334 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02123519 0,09306352 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02123519 0,09289431 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02123519 0,09272572 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02123519 0,09255774 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02123519 0,09239036 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02123519 0,0922236 ! response to redox state GO:0051775 5 5 0,000 0,02123519 0,09205743 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02123519 0,09189186 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02123519 0,09172688 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02123519 0,09156249 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02123519 0,0913987 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02123519 0,09123549 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02123519 0,09107285 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02123519 0,0909108 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02123519 0,09074933 ! striatum development GO:0021756 9 5 0,000 0,02123519 0,09058842 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02123519 0,09042809 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02123519 0,09026832 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02123519 0,09010912 ! glial cell migration GO:0008347 11 5 0,000 0,02123519 0,08995048 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02123519 0,08979239 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02123519 0,08963486 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02123519 0,08947788 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02123519 0,08932145 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02123519 0,08916557 ! neuroprotection GO:0043526 6 5 0,000 0,02123519 0,08901023 ! neural plate development GO:0001840 8 5 0,000 0,02123519 0,08885543 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02123519 0,08870117 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02123519 0,08854744 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02123519 0,08839424 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02123519 0,08824157 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02123519 0,08808943 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02123519 0,08793782 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02123519 0,08778672 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02123519 0,08763614 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02123519 0,08748608 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02123519 0,08733653 ! spindle assembly GO:0051225 6 5 0,000 0,02123519 0,08718749 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02123519 0,08703896 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02123519 0,08689094 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02123519 0,08674342 ! drug metabolic process GO:0017144 6 5 0,000 0,02123519 0,08659639 ! stem cell division GO:0017145 11 5 0,000 0,02123519 0,08644987 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02123519 0,08630384 ! organ regeneration GO:0031100 7 5 0,000 0,02123519 0,0861583 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02123519 0,08601325 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02123519 0,08586869 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02123519 0,08572462 ! cell maturation GO:0048469 100 53 1,000 0,02175699 0,08768395 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02253136 0,09065292 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,02253136 0,09050158 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,023317 0,09350118 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,023317 0,0933456 ! nuclear export GO:0051168 97 55 1,000 0,023317 0,09319054 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02411381 0,09621532 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02411381 0,09605602 ! muscle fiber development GO:0048747 112 57 1,000 0,02492169 0,09911005 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,02492169 0,0989465 ! lipid modification GO:0030258 97 57 1,000 0,02492169 0,09878349 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02492169 0,09862102 ! maintenance of location GO:0051235 118 57 1,000 0,02492169 0,09845908 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02542823 0,1002956 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02542823 0,10013145 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02542823 0,09996783 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02542823 0,09980475 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02542823 0,0996422 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02542823 0,09948018 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02542823 0,09931869 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02542823 0,09915772 ! sleep GO:0030431 13 6 0,000 0,02542823 0,09899727 ! response to oxygen radical GO:0000305 11 6 0,000 0,02542823 0,09883734 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02542823 0,09867792 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02542823 0,09851902 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02542823 0,09836063 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02542823 0,09820275 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02542823 0,09804537 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02542823 0,0978885 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02542823 0,09773213 ! forebrain regionalization GO:0021871 8 6 0,000 0,02542823 0,09757626 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02542823 0,09742088 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02542823 0,097266 ! response to zinc ion GO:0010043 9 6 0,000 0,02542823 0,09711161 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02542823 0,09695771 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02542823 0,09680429 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02542823 0,09665136 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02542823 0,09649892 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02542823 0,09634695 ! malate metabolic process GO:0006108 11 6 0,000 0,02542823 0,09619546 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02542823 0,09604445 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02542823 0,09589391 ! protein refolding GO:0042026 15 6 0,000 0,02542823 0,09574384 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02542823 0,09559424 ! opsonization GO:0008228 8 6 0,000 0,02542823 0,09544511 ! mating behavior GO:0007617 7 6 0,000 0,02542823 0,09529644 ! neuron remodeling GO:0016322 15 6 0,000 0,02542823 0,09514823 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02542823 0,09500049 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02542823 0,0948532 ! equilibrioception GO:0050957 14 6 0,000 0,02542823 0,09470637 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02542823 0,09455999 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02542823 0,09441406 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02542823 0,09426859 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02542823 0,09412356 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02542823 0,09397898 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02542823 0,09383484 ! toxin metabolic process GO:0009404 11 6 0,000 0,02542823 0,09369114 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02542823 0,09354788 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02542823 0,09340506 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02542823 0,09326267 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02542823 0,09312072 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02542823 0,0929792 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02542823 0,09283811 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02542823 0,09269744 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02542823 0,09255721 ! thymic T cell selection GO:0045061 12 6 0,000 0,02542823 0,09241739 ! protein lipoylation GO:0009249 10 6 0,000 0,02542823 0,092278 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02542823 0,09213903 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02542823 0,09200047 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02542823 0,09186233 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02542823 0,09172461 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02542823 0,0915873 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02542823 0,09145039 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02542823 0,0913139 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02542823 0,09117781 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02542823 0,09104213 ! hyperosmotic response GO:0006972 9 6 0,000 0,02542823 0,09090685 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02542823 0,09077198 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02542823 0,0906375 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02542823 0,09050342 ! urea metabolic process GO:0019627 7 6 0,000 0,02542823 0,09036974 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02542823 0,09023645 ! neutrophil activation GO:0042119 8 6 0,000 0,02542823 0,09010355 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02542823 0,08997105 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02542823 0,08983893 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02542823 0,0897072 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02542823 0,08957586 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02542823 0,0894449 ! neuron apoptosis GO:0051402 9 6 0,000 0,02542823 0,08931433 ! nucleoside salvage GO:0043174 9 6 0,000 0,02542823 0,08918413 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02542823 0,08905431 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02542823 0,08892487 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02542823 0,08879581 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02542823 0,08866712 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02542823 0,0885388 ! carnitine transport GO:0015879 10 6 0,000 0,02542823 0,08841086 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02542823 0,08828328 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02542823 0,08815607 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02542823 0,08802923 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02542823 0,08790275 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02542823 0,08777663 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02542823 0,08765088 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02542823 0,08752548 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02542823 0,08740045 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02542823 0,08727577 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02542823 0,08715144 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02542823 0,08702747 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02542823 0,08690385 ! neural nucleus development GO:0048857 14 6 0,000 0,02542823 0,08678059 ! astrocyte development GO:0014002 15 6 0,000 0,02542823 0,08665767 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02542823 0,0865351 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02542823 0,08641287 ! interaction with symbiont GO:0051702 13 6 0,000 0,02542823 0,08629099 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02542823 0,08616946 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02542823 0,08604826 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02542823 0,08592741 ! response to copper ion GO:0046688 10 6 0,000 0,02542823 0,08580689 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02542823 0,08568671 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02542823 0,08556687 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02542823 0,08544736 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02542823 0,08532819 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02542823 0,08520935 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02542823 0,08509084 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02542823 0,08497266 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02542823 0,0848548 ! hair follicle maturation GO:0048820 7 6 0,000 0,02542823 0,08473728 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02542823 0,08462007 ! Schwann cell development GO:0014044 15 6 0,000 0,02542823 0,08450319 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02542823 0,08438664 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02542823 0,0842704 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02542823 0,08415449 ! subpallium development GO:0021544 10 6 0,000 0,02542823 0,08403889 ! histone ubiquitination GO:0016574 8 6 0,000 0,02542823 0,08392361 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02542823 0,08380865 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02542823 0,083694 ! G2 phase GO:0051319 16 6 0,000 0,02542823 0,08357966 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02542823 0,08346564 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02542823 0,08335193 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02542823 0,08323852 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02542823 0,08312543 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02542823 0,08301264 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02542823 0,08290015 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02542823 0,08278797 ! receptor internalization GO:0031623 10 6 0,000 0,02542823 0,0826761 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02542823 0,08256453 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02542823 0,08245325 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02542823 0,08234228 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02542823 0,0822316 ! protein deubiquitination GO:0016579 14 6 0,000 0,02542823 0,08212123 ! protein destabilization GO:0031648 9 6 0,000 0,02542823 0,08201114 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02542823 0,08190136 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02542823 0,08179186 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02542823 0,08168266 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02542823 0,08157375 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02542823 0,08146513 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02542823 0,0813568 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02542823 0,08124876 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02542823 0,081141 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02542823 0,08103353 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02542823 0,08092634 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02542823 0,08081944 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02542823 0,08071281 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02542823 0,08060647 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02542823 0,08050041 ! catecholamine transport GO:0051937 9 6 0,000 0,02542823 0,08039463 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02542823 0,08028912 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02542823 0,0801839 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02542823 0,08007894 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02542823 0,07997427 ! maternal placenta development GO:0001893 12 6 0,000 0,02542823 0,07986986 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02542823 0,07976573 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02542823 0,07966187 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02542823 0,07955827 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02542823 0,07945495 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02542823 0,0793519 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02542823 0,07924911 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02542823 0,07914659 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02574051 0,08001508 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02657018 0,08248756 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,02657018 0,08238126 ! DNA catabolic process GO:0006308 86 59 1,000 0,02657018 0,08227523 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02657018 0,08216948 ! ear development GO:0043583 103 62 1,000 0,0291232 0,08994919 ! gonad development GO:0008406 98 62 1,000 0,0291232 0,08983387 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0291232 0,08971885 ! tRNA transcription GO:0009304 14 7 0,000 0,02960344 0,09108167 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02960344 0,09096535 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02960344 0,09084932 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02960344 0,09073359 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02960344 0,09061815 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02960344 0,09050301 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02960344 0,09038816 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02960344 0,0902736 ! prostate gland development GO:0030850 13 7 0,000 0,02960344 0,09015933 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02960344 0,09004535 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02960344 0,08993165 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02960344 0,08981825 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02960344 0,08970512 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02960344 0,08959229 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02960344 0,08947974 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02960344 0,08936746 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02960344 0,08925548 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02960344 0,08914377 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02960344 0,08903234 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02960344 0,08892119 ! glycolipid transport GO:0046836 10 7 0,000 0,02960344 0,08881031 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02960344 0,08869971 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02960344 0,08858939 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02960344 0,08847934 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02960344 0,08836956 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02960344 0,08826006 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02960344 0,08815083 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02960344 0,08804187 ! mRNA stabilization GO:0048255 18 7 0,000 0,02960344 0,08793317 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02960344 0,08782475 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02960344 0,08771659 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02960344 0,0876087 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02960344 0,08750107 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02960344 0,0873937 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02960344 0,0872866 ! lipoprotein transport GO:0042953 14 7 0,000 0,02960344 0,08717977 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02960344 0,08707319 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02960344 0,08696687 ! rhythmic behavior GO:0007622 15 7 0,000 0,02960344 0,08686082 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02960344 0,08675502 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02960344 0,08664948 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02960344 0,08654419 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02960344 0,08643916 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02960344 0,08633439 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02960344 0,08622987 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02960344 0,0861256 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02960344 0,08602158 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02960344 0,08591782 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02960344 0,0858143 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02960344 0,08571103 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02960344 0,08560802 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02960344 0,08550525 ! spinal cord patterning GO:0021511 13 7 0,000 0,02960344 0,08540272 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02960344 0,08530044 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02960344 0,08519841 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02960344 0,08509662 ! adrenal gland development GO:0030325 17 7 0,000 0,02960344 0,08499507 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02960344 0,08489377 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02960344 0,0847927 ! ovulation GO:0030728 9 7 0,000 0,02960344 0,08469188 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02960344 0,08459129 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02960344 0,08449095 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02960344 0,08439084 ! microtubule nucleation GO:0007020 20 7 0,000 0,02960344 0,08429097 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02960344 0,08419133 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02960344 0,08409194 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02960344 0,08399277 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02960344 0,08389384 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02960344 0,08379514 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02960344 0,08369667 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02960344 0,08359844 ! galactose metabolic process GO:0006012 13 7 0,000 0,02960344 0,08350043 ! vesicle fusion GO:0006906 17 7 0,000 0,02960344 0,08340266 ! response to dietary excess GO:0002021 8 7 0,000 0,02960344 0,08330511 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02960344 0,08320779 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02960344 0,0831107 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02960344 0,08301383 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02960344 0,08291719 ! organ growth GO:0035265 15 7 0,000 0,02960344 0,08282078 ! purine salvage GO:0043101 10 7 0,000 0,02960344 0,08272459 ! nucleoside transport GO:0015858 8 7 0,000 0,02960344 0,08262862 ! parturition GO:0007567 14 7 0,000 0,02960344 0,08253287 ! rRNA modification GO:0000154 14 7 0,000 0,02960344 0,08243735 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02960344 0,08234205 ! spindle checkpoint GO:0031577 15 7 0,000 0,02960344 0,08224696 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02960344 0,0821521 ! macrophage differentiation GO:0030225 11 7 0,000 0,02960344 0,08205745 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02960344 0,08196303 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02960344 0,08186882 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02960344 0,08177482 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02960344 0,08168104 ! fibrinolysis GO:0042730 10 7 0,000 0,02960344 0,08158748 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02960344 0,08149413 ! eating behavior GO:0042755 7 7 0,000 0,02960344 0,08140099 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02960344 0,08130807 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02960344 0,08121536 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02960344 0,08112286 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02960344 0,08103057 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02960344 0,08093849 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02960344 0,08084662 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02960344 0,08075495 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02960344 0,0806635 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02960344 0,08057225 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02960344 0,08048121 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02960344 0,08039037 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02960344 0,08029974 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02960344 0,08020931 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02960344 0,08011909 ! regulation of meiosis GO:0040020 12 7 0,000 0,02960344 0,08002907 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02960344 0,07993925 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02960344 0,07984963 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02960344 0,07976021 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02960344 0,07967099 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02960344 0,07958198 ! anaphase GO:0051322 17 7 0,000 0,02960344 0,07949316 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02960344 0,07940454 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02960344 0,07931611 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02960344 0,07922789 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02960344 0,07913985 ! diuresis GO:0030146 12 7 0,000 0,02960344 0,07905202 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02960344 0,07896438 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02960344 0,07887693 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02960344 0,07878968 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02960344 0,07870262 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02960344 0,07861575 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02960344 0,07852907 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02960344 0,07844259 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02960344 0,07835629 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02960344 0,07827019 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02960344 0,07818427 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02960344 0,07809854 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02960344 0,078013 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02960344 0,07792765 ! lymph node development GO:0048535 10 7 0,000 0,02960344 0,07784248 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02960344 0,0777575 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02960344 0,0776727 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02960344 0,07758809 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02960344 0,07750367 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02960344 0,07741942 ! adult feeding behavior GO:0008343 9 7 0,000 0,02960344 0,07733536 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02960344 0,07725149 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02960344 0,07716779 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02960344 0,07708427 ! muscle adaptation GO:0043500 14 7 0,000 0,02960344 0,07700094 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02960344 0,07691779 ! retina homeostasis GO:0001895 12 7 0,000 0,02960344 0,07683481 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02960344 0,07675201 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02960344 0,0766694 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02960344 0,07658696 ! protein prenylation GO:0018342 18 7 0,000 0,02960344 0,07650469 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02960344 0,07642261 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02960344 0,0763407 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02960344 0,07625896 ! detection of external stimulus GO:0009581 91 63 1,000 0,02999519 0,07718549 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,03087751 0,07937103 ! germ cell development GO:0007281 118 65 1,000 0,03177004 0,08157813 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,03267268 0,08380648 ! cell projection assembly GO:0030031 120 66 1,000 0,03267268 0,08371723 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,03358534 0,08596419 ! lung development GO:0030324 144 67 1,000 0,03358534 0,08587283 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,03358534 0,08578167 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0337609 0,08613862 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0337609 0,08604737 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0337609 0,08595632 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0337609 0,08586546 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0337609 0,08577478 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0337609 0,0856843 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0337609 0,08559402 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0337609 0,08550392 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0337609 0,08541401 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0337609 0,08532429 ! meiotic prophase I GO:0007128 13 8 0,000 0,0337609 0,08523475 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0337609 0,08514541 ! oligopeptide transport GO:0006857 15 8 0,000 0,0337609 0,08505625 ! UTP metabolic process GO:0046051 8 8 0,000 0,0337609 0,08496728 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0337609 0,0848785 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0337609 0,0847899 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0337609 0,08470148 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0337609 0,08461325 ! succinate metabolic process GO:0006105 14 8 0,000 0,0337609 0,0845252 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0337609 0,08443734 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0337609 0,08434966 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0337609 0,08426216 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0337609 0,08417484 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0337609 0,0840877 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0337609 0,08400075 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0337609 0,08391397 ! reflex GO:0060004 16 8 0,000 0,0337609 0,08382737 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0337609 0,08374095 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0337609 0,08365471 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0337609 0,08356864 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0337609 0,08348276 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0337609 0,08339704 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0337609 0,08331151 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0337609 0,08322615 ! pigment granule organization GO:0048753 16 8 0,000 0,0337609 0,08314096 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0337609 0,08305595 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0337609 0,08297111 ! histidine metabolic process GO:0006547 16 8 0,000 0,0337609 0,08288645 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0337609 0,08280196 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0337609 0,08271764 ! glycine catabolic process GO:0006546 13 8 0,000 0,0337609 0,08263349 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0337609 0,08254951 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0337609 0,08246571 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0337609 0,08238207 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0337609 0,0822986 ! melanin metabolic process GO:0006582 15 8 0,000 0,0337609 0,0822153 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0337609 0,08213217 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0337609 0,08204921 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0337609 0,08196642 ! macrophage activation GO:0042116 12 8 0,000 0,0337609 0,08188379 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0337609 0,08180133 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0337609 0,08171904 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0337609 0,08163691 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0337609 0,08155494 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0337609 0,08147314 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0337609 0,0813915 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0337609 0,08131003 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0337609 0,08122872 ! osteoblast development GO:0002076 16 8 0,000 0,0337609 0,08114757 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0337609 0,08106659 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0337609 0,08098576 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0337609 0,0809051 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0337609 0,0808246 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0337609 0,08074426 ! response to UV-B GO:0010224 16 8 0,000 0,0337609 0,08066407 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0337609 0,08058405 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0337609 0,08050418 ! intermediate filament organization GO:0045109 12 8 0,000 0,0337609 0,08042448 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0337609 0,08034493 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0337609 0,08026553 ! cellular extravasation GO:0045123 12 8 0,000 0,0337609 0,0801863 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0337609 0,08010722 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0337609 0,0800283 ! response to antibiotic GO:0046677 11 8 0,000 0,0337609 0,07994953 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0337609 0,07987092 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0337609 0,07979246 ! DNA topological change GO:0006265 12 8 0,000 0,0337609 0,07971415 ! response to tropane GO:0014073 15 8 0,000 0,0337609 0,079636 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0337609 0,079558 ! melanosome transport GO:0032402 13 8 0,000 0,0337609 0,07948016 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0337609 0,07940246 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0337609 0,07932492 ! mast cell activation GO:0045576 14 8 0,000 0,0337609 0,07924753 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0337609 0,07917029 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0337609 0,0790932 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0337609 0,07901627 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0337609 0,07893948 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0337609 0,07886284 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0337609 0,07878634 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0337609 0,07871 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0337609 0,07863381 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0337609 0,07855776 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0337609 0,07848186 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0337609 0,0784061 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0337609 0,07833049 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0337609 0,07825503 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0337609 0,07817971 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0337609 0,07810454 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0337609 0,07802951 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0337609 0,07795463 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0337609 0,07787989 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0337609 0,07780529 ! hormone catabolic process GO:0042447 17 8 0,000 0,0337609 0,07773083 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0337609 0,07765652 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0337609 0,07758235 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0337609 0,07750832 ! ATP catabolic process GO:0006200 11 8 0,000 0,0337609 0,07743443 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0337609 0,07736069 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0337609 0,07728708 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0337609 0,07721361 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0337609 0,07714029 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0337609 0,0770671 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0337609 0,07699405 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0337609 0,07692114 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0337609 0,07684836 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0337609 0,07677573 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0337609 0,07670323 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0337609 0,07663087 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0337609 0,07655864 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0337609 0,07648655 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0337609 0,0764146 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0337609 0,07634278 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0337609 0,0762711 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0337609 0,07619955 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,03450792 0,0778126 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03450792 0,07773974 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,03450792 0,07766702 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,03450792 0,07759443 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,0354403 0,07961658 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,0354403 0,07954231 ! respiratory tube development GO:0030323 150 70 1,000 0,0363824 0,08158066 ! reproductive structure development GO:0048608 113 71 1,000 0,03733411 0,08363674 ! B cell activation GO:0042113 160 71 1,000 0,03733411 0,08355894 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,03733411 0,08348128 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03790069 0,0846695 ! axon extension GO:0048675 15 9 0,000 0,03790069 0,08459095 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03790069 0,08451256 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03790069 0,0844343 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03790069 0,0843562 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03790069 0,08427823 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03790069 0,08420041 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03790069 0,08412274 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03790069 0,08404521 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03790069 0,08396782 ! phosphate transport GO:0006817 19 9 0,000 0,03790069 0,08389057 ! reproductive behavior GO:0019098 19 9 0,000 0,03790069 0,08381346 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03790069 0,0837365 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03790069 0,08365968 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03790069 0,083583 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03790069 0,08350645 ! GTP metabolic process GO:0046039 9 9 0,000 0,03790069 0,08343005 ! RNA methylation GO:0001510 15 9 0,000 0,03790069 0,08335379 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03790069 0,08327767 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03790069 0,08320169 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03790069 0,08312584 ! artery development GO:0060840 24 9 0,000 0,03790069 0,08305013 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03790069 0,08297457 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03790069 0,08289913 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03790069 0,08282384 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03790069 0,08274868 ! chemosensory behavior GO:0007635 20 9 0,000 0,03790069 0,08267366 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03790069 0,08259878 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03790069 0,08252403 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03790069 0,08244941 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03790069 0,08237493 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03790069 0,08230058 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03790069 0,08222637 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03790069 0,0821523 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03790069 0,08207835 ! protein targeting to ER GO:0045047 22 9 0,000 0,03790069 0,08200454 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03790069 0,08193086 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03790069 0,08185731 ! T cell selection GO:0045058 23 9 0,000 0,03790069 0,0817839 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03790069 0,08171062 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03790069 0,08163746 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03790069 0,08156444 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03790069 0,08149155 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03790069 0,08141879 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03790069 0,08134616 ! mannose metabolic process GO:0006013 13 9 0,000 0,03790069 0,08127366 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03790069 0,08120129 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03790069 0,08112905 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03790069 0,08105693 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03790069 0,08098495 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03790069 0,08091309 ! ruffle organization GO:0031529 15 9 0,000 0,03790069 0,08084135 ! retinol metabolic process GO:0042572 18 9 0,000 0,03790069 0,08076975 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03790069 0,08069827 ! behavioral fear response GO:0001662 22 9 0,000 0,03790069 0,08062692 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03790069 0,0805557 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03790069 0,0804846 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03790069 0,08041362 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,03790069 0,08034277 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03790069 0,08027205 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03790069 0,08020145 ! segment specification GO:0007379 13 9 0,000 0,03790069 0,08013097 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03790069 0,08006062 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03790069 0,07999039 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03790069 0,07992029 ! response to amine stimulus GO:0014075 13 9 0,000 0,03790069 0,0798503 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03790069 0,07978044 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03790069 0,07971071 ! erythrocyte development GO:0048821 15 9 0,000 0,03790069 0,07964109 ! gas homeostasis GO:0033483 16 9 0,000 0,03790069 0,0795716 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03790069 0,07950222 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03790069 0,07943297 ! renal water homeostasis GO:0003091 14 9 0,000 0,03790069 0,07936384 ! postreplication repair GO:0006301 22 9 0,000 0,03790069 0,07929482 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03790069 0,07922593 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03790069 0,07915716 ! icosanoid secretion GO:0032309 15 9 0,000 0,03790069 0,07908851 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03790069 0,07901997 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03790069 0,07895156 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03790069 0,07888326 ! regulation of cell division GO:0051302 15 9 0,000 0,03790069 0,07881508 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03790069 0,07874702 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03790069 0,07867908 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03790069 0,07861125 ! sterol catabolic process GO:0016127 11 9 0,000 0,03790069 0,07854354 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03790069 0,07847595 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03790069 0,07840847 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03790069 0,07834111 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03790069 0,07827386 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03790069 0,07820673 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03790069 0,07813972 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03790069 0,07807282 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03790069 0,07800603 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03790069 0,07793936 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03790069 0,0778728 ! purine base metabolic process GO:0006144 21 9 0,000 0,03790069 0,07780636 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03790069 0,07774002 ! pigment granule transport GO:0051904 17 9 0,000 0,03790069 0,07767381 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03790069 0,0776077 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03790069 0,07754171 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03790069 0,07747583 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03790069 0,07741006 ! mitochondrion localization GO:0051646 15 9 0,000 0,03790069 0,0773444 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03829533 0,07808354 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,03829533 0,07801742 ! carbohydrate transport GO:0008643 110 72 1,000 0,03829533 0,07795141 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,03829533 0,07788552 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,03829533 0,07781974 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,03829533 0,07775407 ! respiratory system development GO:0060541 153 72 1,000 0,03829533 0,07768851 ! meiosis GO:0007126 121 74 1,000 0,04024594 0,08157687 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04123513 0,08351156 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04123513 0,08344132 ! meiotic cell cycle GO:0051321 122 75 1,000 0,04123513 0,0833712 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04202287 0,08489255 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04202287 0,08482133 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04202287 0,08475024 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04202287 0,08467926 ! synapsis GO:0007129 13 10 0,000 0,04202287 0,08460839 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04202287 0,08453765 ! N-glycan processing GO:0006491 20 10 0,000 0,04202287 0,08446703 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04202287 0,08439652 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04202287 0,08432613 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04202287 0,08425586 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04202287 0,0841857 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04202287 0,08411567 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04202287 0,08404574 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04202287 0,08397594 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04202287 0,08390625 ! androgen metabolic process GO:0008209 17 10 0,000 0,04202287 0,08383668 ! phospholipid efflux GO:0033700 16 10 0,000 0,04202287 0,08376722 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04202287 0,08369787 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04202287 0,08362864 ! lung alveolus development GO:0048286 26 10 0,000 0,04202287 0,08355953 ! pathogenesis GO:0009405 13 10 0,000 0,04202287 0,08349053 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04202287 0,08342164 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04202287 0,08335287 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04202287 0,08328421 ! endoderm development GO:0007492 16 10 0,000 0,04202287 0,08321566 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04202287 0,08314723 ! arginine catabolic process GO:0006527 13 10 0,000 0,04202287 0,08307891 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04202287 0,0830107 ! proline metabolic process GO:0006560 13 10 0,000 0,04202287 0,0829426 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04202287 0,08287462 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04202287 0,08280674 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04202287 0,08273898 ! V(D)J recombination GO:0033151 28 10 0,000 0,04202287 0,08267133 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04202287 0,08260378 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04202287 0,08253635 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04202287 0,08246903 ! B cell proliferation GO:0042100 18 10 0,000 0,04202287 0,08240182 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04202287 0,08233472 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04202287 0,08226772 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04202287 0,08220084 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04202287 0,08213406 ! epithelial cell development GO:0002064 20 10 0,000 0,04202287 0,08206739 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04202287 0,08200084 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04202287 0,08193438 ! macroautophagy GO:0016236 17 10 0,000 0,04202287 0,08186804 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04202287 0,0818018 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04202287 0,08173568 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04202287 0,08166965 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04202287 0,08160374 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04202287 0,08153793 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04202287 0,08147222 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04202287 0,08140663 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04202287 0,08134113 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04202287 0,08127575 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04202287 0,08121047 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04202287 0,08114529 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04202287 0,08108022 ! response to dsRNA GO:0043331 20 10 0,000 0,04202287 0,08101525 ! DNA ligation GO:0006266 19 10 0,000 0,04202287 0,08095038 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04202287 0,08088562 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04202287 0,08082097 ! melanosome localization GO:0032400 16 10 0,000 0,04202287 0,08075641 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04202287 0,08069196 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04202287 0,08062762 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04202287 0,08056337 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04202287 0,08049923 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04202287 0,08043519 ! mRNA cleavage GO:0006379 17 10 0,000 0,04202287 0,08037125 ! protein sumoylation GO:0016925 15 10 0,000 0,04202287 0,08030741 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04202287 0,08024367 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04202287 0,08018004 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04202287 0,08011651 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04202287 0,08005307 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04202287 0,07998974 ! salivary gland development GO:0007431 27 10 0,000 0,04202287 0,07992651 ! prophase GO:0051324 15 10 0,000 0,04202287 0,07986337 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04202287 0,07980034 ! apical protein localization GO:0045176 15 10 0,000 0,04202287 0,07973741 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04202287 0,07967457 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04202287 0,07961184 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04202287 0,0795492 ! midbrain development GO:0030901 13 10 0,000 0,04202287 0,07948666 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04202287 0,07942422 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04202287 0,07936188 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04202287 0,07929963 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04202287 0,07923748 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04202287 0,07917543 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04202287 0,07911348 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04202287 0,07905163 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04202287 0,07898987 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04202287 0,0789282 ! blastocyst formation GO:0001825 17 10 0,000 0,04202287 0,07886664 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04202287 0,07880517 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04202287 0,07874379 ! activation of innate immune response GO:0002218 12 10 0,000 0,04202287 0,07868251 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04202287 0,07862133 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04202287 0,07856024 ! response to nicotine GO:0035094 20 10 0,000 0,04202287 0,07849925 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04202287 0,07843835 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04202287 0,07837754 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04202287 0,07831683 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04223345 0,07864837 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,04324081 0,08046201 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04324081 0,08039983 ! protein oligomerization GO:0051259 139 78 1,000 0,0442571 0,08222594 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,04528224 0,08406564 ! respiratory burst GO:0045730 17 11 0,000 0,04612753 0,08556889 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04612753 0,08550296 ! neuron fate specification GO:0048665 17 11 0,000 0,04612753 0,08543714 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04612753 0,08537142 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04612753 0,0853058 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04612753 0,08524028 ! thyroid gland development GO:0030878 26 11 0,000 0,04612753 0,08517486 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04612753 0,08510954 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04612753 0,08504433 ! response to pain GO:0048265 24 11 0,000 0,04612753 0,08497921 ! T cell proliferation GO:0042098 26 11 0,000 0,04612753 0,08491419 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04612753 0,08484927 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04612753 0,08478445 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04612753 0,08471973 ! bone resorption GO:0045453 16 11 0,000 0,04612753 0,08465511 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04612753 0,08459058 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04612753 0,08452616 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04612753 0,08446183 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04612753 0,0843976 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04612753 0,08433347 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04612753 0,08426944 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04612753 0,0842055 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04612753 0,08414166 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04612753 0,08407791 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04612753 0,08401427 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04612753 0,08395072 ! UV protection GO:0009650 19 11 0,000 0,04612753 0,08388726 ! adult heart development GO:0007512 14 11 0,000 0,04612753 0,0838239 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04612753 0,08376064 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04612753 0,08369747 ! temperature homeostasis GO:0001659 17 11 0,000 0,04612753 0,0836344 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04612753 0,08357142 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04612753 0,08350854 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04612753 0,08344575 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04612753 0,08338306 ! regulation of organ growth GO:0046620 13 11 0,000 0,04612753 0,08332046 ! pigment granule localization GO:0051875 20 11 0,000 0,04612753 0,08325795 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04612753 0,08319554 ! vasoconstriction GO:0042310 18 11 0,000 0,04612753 0,08313322 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04612753 0,08307099 ! embryonic axis specification GO:0000578 18 11 0,000 0,04612753 0,08300886 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04612753 0,08294682 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04612753 0,08288487 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04612753 0,08282302 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04612753 0,08276126 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04612753 0,08269959 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04612753 0,08263801 ! zymogen activation GO:0031638 15 11 0,000 0,04612753 0,08257652 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04612753 0,08251513 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04612753 0,08245382 ! nucleosome positioning GO:0016584 15 11 0,000 0,04612753 0,08239261 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04612753 0,08233149 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04612753 0,08227046 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04612753 0,08220952 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04612753 0,08214867 ! acid secretion GO:0046717 18 11 0,000 0,04612753 0,0820879 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04612753 0,08202723 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04612753 0,08196665 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04612753 0,08190616 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04612753 0,08184576 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04612753 0,08178544 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04612753 0,08172522 ! cholesterol efflux GO:0033344 19 11 0,000 0,04612753 0,08166508 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04612753 0,08160503 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04612753 0,08154507 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04612753 0,0814852 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04612753 0,08142542 ! embryonic gut development GO:0048566 15 11 0,000 0,04612753 0,08136572 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04612753 0,08130611 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04612753 0,08124659 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04612753 0,08118716 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04612753 0,08112781 ! defense response to fungus GO:0050832 13 11 0,000 0,04612753 0,08106855 ! developmental induction GO:0031128 19 11 0,000 0,04612753 0,08100938 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04612753 0,08095029 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04612753 0,08089129 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04612753 0,08083237 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04612753 0,08077354 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04612753 0,0807148 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04612753 0,08065614 ! nucleus localization GO:0051647 19 11 0,000 0,04612753 0,08059756 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04612753 0,08053908 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,04631613 0,08080973 ! response to metal ion GO:0010038 140 80 1,000 0,04631613 0,08075117 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,04735869 0,08250905 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,04735869 0,08244935 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,04840981 0,08421837 ! response to drug GO:0042493 143 82 1,000 0,04840981 0,08415752 ! response to nutrient GO:0007584 125 82 1,000 0,04840981 0,08409675 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,04840981 0,08403608 ! regulation of lyase activity GO:0051339 160 83 1,000 0,04946941 0,08581355 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05021474 0,08704371 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05021474 0,08698105 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05021474 0,08691847 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05021474 0,08685598 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05021474 0,08679359 ! virus-host interaction GO:0019048 29 12 0,000 0,05021474 0,08673128 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05021474 0,08666906 ! cartilage condensation GO:0001502 20 12 0,000 0,05021474 0,08660693 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05021474 0,0865449 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05021474 0,08648294 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05021474 0,08642108 ! hippocampus development GO:0021766 26 12 0,000 0,05021474 0,08635931 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05021474 0,08629762 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05021474 0,08623603 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05021474 0,08617452 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05021474 0,0861131 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05021474 0,08605176 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05021474 0,08599052 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05021474 0,08592936 ! drug transport GO:0015893 16 12 0,000 0,05021474 0,08586828 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05021474 0,0858073 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05021474 0,0857464 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05021474 0,08568558 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05021474 0,08562486 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05021474 0,08556422 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05021474 0,08550366 ! forebrain cell migration GO:0021885 21 12 0,000 0,05021474 0,08544319 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05021474 0,08538281 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05021474 0,08532251 ! entry into host cell GO:0030260 32 12 0,000 0,05021474 0,0852623 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05021474 0,08520217 ! monoamine transport GO:0015844 18 12 0,000 0,05021474 0,08514212 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05021474 0,08508216 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05021474 0,08502229 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05021474 0,0849625 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05021474 0,08490279 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05021474 0,08484317 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05021474 0,08478363 ! protein homotetramerization GO:0051289 21 12 0,000 0,05021474 0,08472418 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05021474 0,0846648 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05021474 0,08460551 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05021474 0,08454631 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05021474 0,08448718 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05021474 0,08442814 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05021474 0,08436919 ! cranial nerve development GO:0021545 20 12 0,000 0,05021474 0,08431031 ! fucose catabolic process GO:0019317 22 12 0,000 0,05021474 0,08425152 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05021474 0,0841928 ! histone methylation GO:0016571 26 12 0,000 0,05021474 0,08413417 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05021474 0,08407563 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05021474 0,08401716 ! gland morphogenesis GO:0022612 29 12 0,000 0,05021474 0,08395877 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05021474 0,08390047 ! T cell homeostasis GO:0043029 25 12 0,000 0,05021474 0,08384224 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05021474 0,0837841 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05021474 0,08372604 ! spleen development GO:0048536 22 12 0,000 0,05021474 0,08366806 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05021474 0,08361016 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05021474 0,08355233 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05021474 0,08349459 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05021474 0,08343693 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05021474 0,08337935 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05021474 0,08332184 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05021474 0,08326442 ! response to cold GO:0009409 17 12 0,000 0,05021474 0,08320708 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05021474 0,08314981 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05021474 0,08309262 ! regulation of ligase activity GO:0051340 142 84 1,000 0,0505374 0,08356905 ! response to unfolded protein GO:0006986 131 85 1,000 0,05161368 0,08529019 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05161368 0,08523165 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,05269817 0,08696282 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,05379078 0,08870501 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cGMP metabolic process GO:0046068 18 13 0,000 0,05428458 0,08945801 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05428458 0,08939678 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05428458 0,08933563 ! peroxisomal transport GO:0043574 24 13 0,000 0,05428458 0,08927457 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05428458 0,08921359 ! lipid localization GO:0010876 28 13 0,000 0,05428458 0,08915269 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05428458 0,08909188 ! organelle fusion GO:0048284 32 13 0,000 0,05428458 0,08903115 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05428458 0,0889705 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05428458 0,08890993 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05428458 0,08884945 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05428458 0,08878905 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05428458 0,08872873 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05428458 0,08866849 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05428458 0,08860834 ! methionine metabolic process GO:0006555 27 13 0,000 0,05428458 0,08854826 ! plasma membrane organization GO:0007009 24 13 0,000 0,05428458 0,08848827 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05428458 0,08842836 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05428458 0,08836853 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05428458 0,08830878 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05428458 0,08824912 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05428458 0,08818953 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05428458 0,08813002 ! exocrine system development GO:0035272 32 13 0,000 0,05428458 0,08807059 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05428458 0,08801125 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05428458 0,08795198 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05428458 0,08789279 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05428458 0,08783369 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05428458 0,08777466 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05428458 0,08771571 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05428458 0,08765684 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05428458 0,08759805 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05428458 0,08753934 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05428458 0,0874807 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05428458 0,08742215 ! ribosome assembly GO:0042255 17 13 0,000 0,05428458 0,08736367 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05428458 0,08730527 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05428458 0,08724695 ! chromatin silencing GO:0006342 26 13 0,000 0,05428458 0,08718871 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05428458 0,08713055 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05428458 0,08707246 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05428458 0,08701445 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05428458 0,08695652 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05428458 0,08689866 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05428458 0,08684088 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05428458 0,08678318 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05428458 0,08672556 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05428458 0,08666801 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05428458 0,08661054 ! embryonic placenta development GO:0001892 23 13 0,000 0,05428458 0,08655314 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05428458 0,08649582 ! insulin secretion GO:0030073 23 13 0,000 0,05428458 0,08643858 ! actin filament polymerization GO:0030041 24 13 0,000 0,05428458 0,08638141 ! acrosome reaction GO:0007340 18 13 0,000 0,05428458 0,08632432 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,05489142 0,08723167 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,056 0,08893465 ! sex differentiation GO:0007548 145 90 1,000 0,05711644 0,09064785 ! response to protein stimulus GO:0051789 149 91 1,000 0,05824064 0,09237112 ! rRNA transcription GO:0009303 25 14 0,000 0,0583371 0,09246316 ! lactation GO:0007595 26 14 0,000 0,0583371 0,09240229 ! reproductive cellular process GO:0048610 20 14 0,000 0,0583371 0,09234149 ! tRNA modification GO:0006400 20 14 0,000 0,0583371 0,09228078 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0583371 0,09222015 ! water transport GO:0006833 21 14 0,000 0,0583371 0,0921596 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0583371 0,09209913 ! non-recombinational repair GO:0000726 25 14 0,000 0,0583371 0,09203874 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0583371 0,09197842 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0583371 0,09191819 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0583371 0,09185803 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0583371 0,09179795 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0583371 0,09173796 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0583371 0,09167804 ! palate development GO:0060021 31 14 0,000 0,0583371 0,09161819 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0583371 0,09155843 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0583371 0,09149874 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0583371 0,09143913 ! arginine metabolic process GO:0006525 17 14 0,000 0,0583371 0,0913796 ! regulation of heart rate GO:0002027 24 14 0,000 0,0583371 0,09132015 ! organic alcohol transport GO:0015850 29 14 0,000 0,0583371 0,09126077 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0583371 0,09120148 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0583371 0,09114225 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0583371 0,09108311 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0583371 0,09102404 ! L-amino acid transport GO:0015807 30 14 0,000 0,0583371 0,09096505 ! stem cell development GO:0048864 43 14 0,000 0,0583371 0,09090613 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0583371 0,0908473 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0583371 0,09078853 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0583371 0,09072985 ! cerebellum development GO:0021549 21 14 0,000 0,0583371 0,09067123 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0583371 0,0906127 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0583371 0,09055424 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0583371 0,09049586 ! cofactor transport GO:0051181 26 14 0,000 0,0583371 0,09043755 ! NADP metabolic process GO:0006739 24 14 0,000 0,0583371 0,09037931 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0583371 0,09032115 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0583371 0,09026307 ! intestinal absorption GO:0050892 25 14 0,000 0,0583371 0,09020506 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0583371 0,09014712 ! oxygen transport GO:0015671 21 14 0,000 0,0583371 0,09008926 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0583371 0,09003148 ! male genitalia development GO:0030539 24 14 0,000 0,0583371 0,08997376 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0583371 0,08991613 ! regulation of axon extension GO:0030516 37 14 0,000 0,0583371 0,08985856 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0583371 0,08980107 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06051202 0,09308946 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 1,000 0,06051202 0,09302998 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,06051202 0,09297057 ! regulation of T cell activation GO:0050863 158 94 1,000 0,06165902 0,09467237 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0623724 0,09570663 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0623724 0,09564563 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0623724 0,09558471 ! superoxide anion generation GO:0042554 20 15 0,000 0,0623724 0,09552387 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0623724 0,0954631 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0623724 0,09540241 ! copper ion transport GO:0006825 20 15 0,000 0,0623724 0,0953418 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0623724 0,09528127 ! sulfate transport GO:0008272 23 15 0,000 0,0623724 0,09522081 ! response to cAMP GO:0051591 22 15 0,000 0,0623724 0,09516043 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0623724 0,09510012 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0623724 0,09503989 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0623724 0,09497974 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0623724 0,09491967 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0623724 0,09485967 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0623724 0,09479974 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0623724 0,09473989 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0623724 0,09468012 ! pituitary gland development GO:0021983 29 15 0,000 0,0623724 0,09462042 ! vesicle coating GO:0006901 33 15 0,000 0,0623724 0,0945608 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0623724 0,09450126 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0623724 0,09444178 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0623724 0,09438239 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0623724 0,09432306 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0623724 0,09426382 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0623724 0,09420464 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0623724 0,09414554 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0623724 0,09408652 ! histone deacetylation GO:0016575 20 15 0,000 0,0623724 0,09402756 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0623724 0,09396869 ! tissue regeneration GO:0042246 26 15 0,000 0,0623724 0,09390988 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0623724 0,09385115 ! water homeostasis GO:0030104 27 15 0,000 0,0623724 0,0937925 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0623724 0,09373391 ! muscle maintenance GO:0046716 26 15 0,000 0,0623724 0,0936754 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0623724 0,09361696 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0623724 0,0935586 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0623724 0,09350031 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0623724 0,09344209 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0623724 0,09338394 ! cell killing GO:0001906 29 15 0,000 0,0623724 0,09332587 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0623724 0,09326786 ! detection of bacterium GO:0016045 18 15 0,000 0,0623724 0,09320993 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0623724 0,09315208 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0623724 0,09309429 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0623724 0,09303657 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0623724 0,09297893 ! peptide hormone processing GO:0016486 23 15 0,000 0,0623724 0,09292136 ! detection of stimulus GO:0051606 151 96 1,000 0,06397523 0,09525024 ! response to virus GO:0009615 160 98 1,000 0,06632048 0,09868094 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06639054 0,09872412 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06639054 0,09866314 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06639054 0,09860224 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06639054 0,09854141 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06639054 0,09848066 ! bone remodeling GO:0046849 27 16 0,000 0,06639054 0,09841998 ! filopodium assembly GO:0046847 32 16 0,000 0,06639054 0,09835938 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06639054 0,09829885 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06639054 0,0982384 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06639054 0,09817802 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06639054 0,09811771 ! startle response GO:0001964 28 16 0,000 0,06639054 0,09805748 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06639054 0,09799732 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06639054 0,09793724 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06639054 0,09787723 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06639054 0,09781729 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06639054 0,09775742 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06639054 0,09769763 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06639054 0,09763792 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06639054 0,09757827 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06639054 0,0975187 ! response to osmotic stress GO:0006970 25 16 0,000 0,06639054 0,0974592 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06639054 0,09739978 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06639054 0,09734042 ! fructose metabolic process GO:0006000 25 16 0,000 0,06639054 0,09728114 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06639054 0,09722193 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06639054 0,09716279 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06639054 0,09710373 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06639054 0,09704473 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06639054 0,09698581 ! axon cargo transport GO:0008088 43 16 0,000 0,06639054 0,09692696 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06639054 0,09686818 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06639054 0,09680947 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06639054 0,09675084 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06639054 0,09669227 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06639054 0,09663378 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06639054 0,09657535 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06639054 0,096517 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06639054 0,09645871 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06639054 0,0964005 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06639054 0,09634236 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06639054 0,09628429 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06639054 0,09622628 ! defense response to virus GO:0051607 37 16 0,000 0,06639054 0,09616835 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,0675038 0,09772211 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07039159 0,10184135 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07039159 0,10178014 ! metencephalon development GO:0022037 30 17 0,000 0,07039159 0,10171901 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07039159 0,10165796 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07039159 0,10159698 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07039159 0,10153607 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07039159 0,10147523 ! endothelial cell migration GO:0043542 28 17 0,000 0,07039159 0,10141447 ! inositol metabolic process GO:0006020 28 17 0,000 0,07039159 0,10135378 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07039159 0,10129316 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07039159 0,10123261 ! glial cell development GO:0021782 27 17 0,000 0,07039159 0,10117214 ! limbic system development GO:0021761 36 17 0,000 0,07039159 0,10111174 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07039159 0,10105141 ! adult walking behavior GO:0007628 33 17 0,000 0,07039159 0,10099115 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07039159 0,10093096 ! heart looping GO:0001947 30 17 0,000 0,07039159 0,10087085 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07039159 0,10081081 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07039159 0,10075084 ! myoblast differentiation GO:0045445 45 17 0,000 0,07039159 0,10069094 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07039159 0,10063111 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07039159 0,10057135 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07039159 0,10051167 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07039159 0,10045205 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07039159 0,10039251 ! NAD metabolic process GO:0019674 29 17 0,000 0,07039159 0,10033303 ! membrane budding GO:0006900 37 17 0,000 0,07039159 0,10027363 ! DNA integration GO:0015074 29 17 0,000 0,07039159 0,1002143 ! regulation of protein binding GO:0043393 33 17 0,000 0,07039159 0,10015503 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07039159 0,10009584 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07039159 0,10003672 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07039159 0,09997766 ! genitalia development GO:0048806 30 17 0,000 0,07039159 0,09991868 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07039159 0,09985976 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07039159 0,09980092 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07039159 0,09974214 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07039159 0,09968344 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07039159 0,0996248 ! steroid catabolic process GO:0006706 31 17 0,000 0,07039159 0,09956623 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07039159 0,09950773 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07039159 0,0994493 ! gas transport GO:0015669 25 17 0,000 0,07039159 0,09939094 ! organic cation transport GO:0015695 31 17 0,000 0,07039159 0,09933264 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07039159 0,09927442 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07039159 0,09921626 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07039159 0,09915817 ! microspike assembly GO:0030035 36 17 0,000 0,07039159 0,09910015 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07039159 0,0990422 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07039159 0,09898431 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07437562 0,10452555 ! neuron maturation GO:0042551 42 18 0,000 0,07437562 0,10446454 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07437562 0,10440359 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07437562 0,10434271 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07437562 0,10428191 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07437562 0,10422117 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07437562 0,10416051 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07437562 0,10409991 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07437562 0,10403939 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07437562 0,10397894 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07437562 0,10391855 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07437562 0,10385824 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07437562 0,103798 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07437562 0,10373783 ! response to retinoic acid GO:0032526 26 18 0,000 0,07437562 0,10367772 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,07437562 0,10361769 ! response to fungus GO:0009620 21 18 0,000 0,07437562 0,10355773 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07437562 0,10349783 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07437562 0,10343801 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07437562 0,10337825 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07437562 0,10331856 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07437562 0,10325894 ! vitamin transport GO:0051180 27 18 0,000 0,07437562 0,10319939 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07437562 0,10313991 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07437562 0,1030805 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07437562 0,10302116 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07437562 0,10296188 ! nerve development GO:0021675 28 18 0,000 0,07437562 0,10290267 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07437562 0,10284353 ! protein secretion GO:0009306 39 19 0,000 0,07834272 0,10826684 ! positive regulation of translation GO:0045727 30 19 0,000 0,07834272 0,10820469 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07834272 0,10814261 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07834272 0,10808061 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,07834272 0,10801867 ! skin development GO:0043588 36 19 0,000 0,07834272 0,1079568 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07834272 0,10789501 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07834272 0,10783328 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07834272 0,10777163 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07834272 0,10771004 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07834272 0,10764853 ! cerebral cortex development GO:0021987 36 19 0,000 0,07834272 0,10758709 ! response to vitamin A GO:0033189 27 19 0,000 0,07834272 0,10752571 ! heme metabolic process GO:0042168 36 19 0,000 0,07834272 0,10746441 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07834272 0,10740318 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07834272 0,10734201 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07834272 0,10728092 ! peptide cross-linking GO:0018149 37 19 0,000 0,07834272 0,1072199 ! heart process GO:0003015 30 19 0,000 0,07834272 0,10715894 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07834272 0,10709805 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07834272 0,10703724 ! visual learning GO:0008542 36 19 0,000 0,07834272 0,10697649 ! cellular pigmentation GO:0033059 36 19 0,000 0,07834272 0,10691581 ! G1 phase GO:0051318 40 19 0,000 0,07834272 0,1068552 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07834272 0,10679466 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,07834272 0,10673419 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07834272 0,10667378 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07834272 0,10661345 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07834272 0,10655318 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07834272 0,10649298 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07834272 0,10643285 ! cilium assembly GO:0042384 37 19 0,000 0,07834272 0,10637279 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07834272 0,10631279 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08229294 0,11161038 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08229294 0,1115475 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08229294 0,11148469 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08229294 0,11142195 ! response to vitamin GO:0033273 31 20 0,000 0,08229294 0,11135929 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08229294 0,11129669 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08229294 0,11123416 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08229294 0,11117171 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08229294 0,11110932 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08229294 0,11104701 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08229294 0,11098476 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08229294 0,11092258 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08229294 0,11086048 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08229294 0,11079844 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08229294 0,11073647 ! body fluid secretion GO:0007589 31 20 0,000 0,08229294 0,11067457 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08229294 0,11061274 ! peptide secretion GO:0002790 35 20 0,000 0,08229294 0,11055098 ! stem cell differentiation GO:0048863 53 20 0,000 0,08229294 0,11048929 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08229294 0,11042767 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08229294 0,11036612 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08229294 0,11030463 ! sensory perception of pain GO:0019233 30 20 0,000 0,08229294 0,11024321 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08229294 0,11018186 ! diencephalon development GO:0021536 34 20 0,000 0,08229294 0,11012058 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08229294 0,11005937 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08229294 0,10999823 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08229294 0,10993715 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08229294 0,10987614 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08229294 0,1098152 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08229294 0,10975433 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08229294 0,10969352 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08229294 0,10963279 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08229294 0,10957211 ! regulation of glucose import GO:0046324 29 20 0,000 0,08229294 0,10951151 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08229294 0,10945097 ! actin filament-based movement GO:0030048 43 20 0,000 0,08229294 0,1093905 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08229294 0,1093301 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08229294 0,10926976 ! negative regulation of translation GO:0017148 29 20 0,000 0,08229294 0,10920949 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08229294 0,10914929 ! regulation of cell killing GO:0031341 42 21 0,000 0,08622636 0,11430337 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08622636 0,11424043 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08622636 0,11417756 ! hormone secretion GO:0046879 38 21 0,000 0,08622636 0,11411476 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08622636 0,11405202 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08622636 0,11398935 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08622636 0,11392676 ! axis specification GO:0009798 38 21 0,000 0,08622636 0,11386423 ! ovarian follicle development GO:0001541 35 21 0,000 0,08622636 0,11380177 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08622636 0,11373938 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08622636 0,11367705 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08622636 0,1136148 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08622636 0,11355261 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08622636 0,1134905 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08622636 0,11342844 ! cytolysis GO:0019835 24 21 0,000 0,08622636 0,11336646 ! vasodilation GO:0042311 39 21 0,000 0,08622636 0,11330455 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08622636 0,1132427 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08622636 0,11318092 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08622636 0,11311921 ! DNA modification GO:0006304 34 21 0,000 0,08622636 0,11305756 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08622636 0,11299598 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08622636 0,11293447 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08622636 0,11287303 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08622636 0,11281165 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08622636 0,11275034 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08622636 0,1126891 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08622636 0,11262792 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08622636 0,11256681 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08622636 0,11250576 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08622636 0,11244478 ! gut development GO:0048565 39 21 0,000 0,08622636 0,11238387 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09014305 0,11742512 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09014305 0,11736157 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09014305 0,1172981 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09014305 0,1172347 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09014305 0,11717136 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09014305 0,11710809 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09014305 0,11704489 ! regeneration GO:0031099 41 22 0,000 0,09014305 0,11698176 ! keratinization GO:0031424 28 22 0,000 0,09014305 0,1169187 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09014305 0,11685571 ! sensory perception of taste GO:0050909 28 22 0,000 0,09014305 0,11679278 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09014305 0,11672992 ! vacuolar transport GO:0007034 36 22 0,000 0,09014305 0,11666713 ! lysosome organization GO:0007040 41 22 0,000 0,09014305 0,1166044 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09014305 0,11654175 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09014305 0,11647916 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09014305 0,11641663 ! fucose metabolic process GO:0006004 39 22 0,000 0,09014305 0,11635418 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09014305 0,11629179 ! ureteric bud development GO:0001657 43 22 0,000 0,09014305 0,11622947 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09014305 0,11616721 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09014305 0,11610503 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09014305 0,1160429 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09014305 0,11598085 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09014305 0,11591886 ! sarcomere organization GO:0045214 30 22 0,000 0,09014305 0,11585694 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09014305 0,11579508 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09014305 0,11573329 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09014305 0,11567157 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09014305 0,11560991 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09404309 0,12054751 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09404309 0,12048332 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09404309 0,1204192 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09404309 0,12035515 ! gluconeogenesis GO:0006094 33 23 0,000 0,09404309 0,12029116 ! viral genome replication GO:0019079 41 23 0,000 0,09404309 0,12022724 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09404309 0,12016339 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09404309 0,12009961 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09404309 0,1200359 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09404309 0,11997225 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09404309 0,11990868 ! visual behavior GO:0007632 42 23 0,000 0,09404309 0,11984517 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09404309 0,11978172 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,09404309 0,11971835 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09404309 0,11965504 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09404309 0,11959179 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09404309 0,11952862 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09404309 0,11946551 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09404309 0,11940247 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09404309 0,11933949 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,09404309 0,11927658 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09404309 0,11921374 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09404309 0,11915096 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09404309 0,11908825 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09404309 0,1190256 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09404309 0,11896302 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09404309 0,11890051 ! fatty acid transport GO:0015908 44 23 0,000 0,09404309 0,11883806 ! platelet activation GO:0030168 37 23 0,000 0,09404309 0,11877568 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09404309 0,11871336 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09404309 0,11865111 ! hormone transport GO:0009914 40 23 0,000 0,09404309 0,11858893 ! cell-cell recognition GO:0009988 25 23 0,000 0,09404309 0,11852681 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09404309 0,11846475 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09404309 0,11840276 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09404309 0,11834083 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09404309 0,11827897 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,09792654 0,12309887 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09792654 0,12303459 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09792654 0,12297038 ! vesicle docking GO:0048278 47 24 0,000 0,09792654 0,12290623 ! spinal cord development GO:0021510 47 24 0,000 0,09792654 0,12284215 ! vacuole organization GO:0007033 43 24 0,000 0,09792654 0,12277814 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09792654 0,12271419 ! digestive system process GO:0022600 39 24 0,000 0,09792654 0,12265031 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09792654 0,1225865 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09792654 0,12252275 ! regulation of behavior GO:0050795 43 24 0,000 0,09792654 0,12245907 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09792654 0,12239545 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09792654 0,1223319 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09792654 0,12226842 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09792654 0,122205 ! membrane depolarization GO:0051899 39 24 0,000 0,09792654 0,12214165 ! pallium development GO:0021543 49 24 0,000 0,09792654 0,12207837 ! pentose metabolic process GO:0019321 35 24 0,000 0,09792654 0,12201515 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,09792654 0,12195199 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09792654 0,1218889 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09792654 0,12182588 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09792654 0,12176292 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09792654 0,12170002 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09792654 0,12163719 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09792654 0,12157443 ! regulation of amine transport GO:0051952 40 24 0,000 0,09792654 0,12151173 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10179346 0,12624488 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10179346 0,12617984 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10179346 0,12611487 ! phototransduction GO:0007602 33 25 0,000 0,10179346 0,12604996 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10179346 0,12598512 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,10179346 0,12592035 ! sperm motility GO:0030317 31 25 0,000 0,10179346 0,12585564 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10179346 0,125791 ! chromosome condensation GO:0030261 45 25 0,000 0,10179346 0,12572642 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10179346 0,12566192 ! neural crest cell development GO:0014032 54 25 0,000 0,10179346 0,12559747 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10179346 0,1255331 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10179346 0,12546879 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10179346 0,12540454 ! interaction with host GO:0051701 62 25 0,000 0,10179346 0,12534037 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10179346 0,12527625 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10179346 0,12521221 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10179346 0,12514822 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10179346 0,12508431 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10179346 0,12502046 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10179346 0,12495667 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10179346 0,12489295 ! telomere organization GO:0032200 43 25 0,000 0,10179346 0,12482929 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,10179346 0,1247657 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10564394 0,12941921 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10564394 0,12935335 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10564394 0,12928755 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10564394 0,12922182 ! initiation of viral infection GO:0019059 57 26 0,000 0,10564394 0,12915616 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10564394 0,12909057 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10564394 0,12902504 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10564394 0,12895958 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10564394 0,12889418 ! molting cycle process GO:0022404 50 26 0,000 0,10564394 0,12882885 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10564394 0,12876359 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10564394 0,12869839 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10564394 0,12863326 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10564394 0,1285682 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10564394 0,1285032 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10564394 0,12843827 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10564394 0,1283734 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,10564394 0,1283086 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10564394 0,12824386 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10564394 0,12817919 ! leukocyte proliferation GO:0070661 52 26 0,000 0,10564394 0,12811458 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10564394 0,12805004 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10564394 0,12798556 ! neuron fate commitment GO:0048663 48 27 0,000 0,10947805 0,13256375 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,10947805 0,13249707 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,10947805 0,13243046 ! iron ion transport GO:0006826 59 27 0,000 0,10947805 0,13236391 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10947805 0,13229743 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10947805 0,13223101 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10947805 0,13216466 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10947805 0,13209838 ! autophagy GO:0006914 41 27 0,000 0,10947805 0,13203217 ! male gonad development GO:0008584 44 27 0,000 0,10947805 0,13196602 ! response to toxin GO:0009636 47 27 0,000 0,10947805 0,13189994 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10947805 0,13183392 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10947805 0,13176797 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10947805 0,13170209 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10947805 0,13163627 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,10947805 0,13157052 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10947805 0,13150483 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11329584 0,13602285 ! circadian rhythm GO:0007623 50 28 0,000 0,11329584 0,135955 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11329584 0,13588723 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11329584 0,13581952 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11329584 0,13575188 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11329584 0,13568431 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11329584 0,13561681 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11329584 0,13554937 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11329584 0,135482 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11329584 0,1354147 ! synaptogenesis GO:0007416 42 28 0,000 0,11329584 0,13534746 ! lipid oxidation GO:0034440 43 28 0,000 0,11329584 0,13528029 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11329584 0,13521319 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11329584 0,13514615 ! translational initiation GO:0006413 65 29 0,000 0,11709739 0,13961165 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,11709739 0,1395425 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11709739 0,13947342 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11709739 0,13940441 ! catechol metabolic process GO:0009712 54 29 0,000 0,11709739 0,13933547 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,11709739 0,13926659 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11709739 0,13919778 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,11709739 0,13912904 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11709739 0,13906037 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11709739 0,13899177 ! cell fate determination GO:0001709 60 29 0,000 0,11709739 0,13892323 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11709739 0,13885476 ! detection of light stimulus GO:0009583 38 29 0,000 0,11709739 0,13878636 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,11709739 0,13871803 ! regulation of coagulation GO:0050818 46 29 0,000 0,11709739 0,13864976 ! phenol metabolic process GO:0018958 55 30 0,000 0,12088276 0,14306145 ! zinc ion transport GO:0006829 45 30 0,000 0,12088276 0,14299112 ! membrane docking GO:0022406 61 30 0,000 0,12088276 0,14292085 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12088276 0,14285065 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12088276 0,14278052 ! acute-phase response GO:0006953 49 30 0,000 0,12088276 0,14271047 ! myofibril assembly GO:0030239 47 30 0,000 0,12088276 0,14264048 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12088276 0,14257055 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12088276 0,1425007 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12088276 0,14243092 ! phospholipid transport GO:0015914 51 30 0,000 0,12088276 0,1423612 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12088276 0,14229155 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12088276 0,14222197 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12088276 0,14215246 ! eye morphogenesis GO:0048592 60 30 0,000 0,12088276 0,14208301 ! response to heat GO:0009408 50 30 0,000 0,12088276 0,14201364 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12465204 0,14637033 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,12465204 0,14629893 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12465204 0,1462276 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12465204 0,14615634 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12465204 0,14608514 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12465204 0,14601402 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12465204 0,14594297 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12465204 0,14587198 ! ovulation cycle process GO:0022602 49 31 0,000 0,12465204 0,14580107 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12465204 0,14573022 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12465204 0,14565945 ! peptide transport GO:0015833 55 31 0,000 0,12465204 0,14558874 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12465204 0,1455181 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,12465204 0,14544753 ! mesoderm formation GO:0001707 69 31 0,000 0,12465204 0,14537702 ! natural killer cell activation GO:0030101 45 31 0,000 0,12465204 0,14530659 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12465204 0,14523622 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12465204 0,14516592 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12465204 0,14509569 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,12840527 0,14939221 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,12840527 0,14932 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12840527 0,14924787 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12840527 0,1491758 ! cholesterol transport GO:0030301 56 32 0,000 0,12840527 0,14910381 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12840527 0,14903188 ! spliceosome assembly GO:0000245 67 32 0,000 0,12840527 0,14896002 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12840527 0,14888824 ! metanephros development GO:0001656 74 32 0,000 0,12840527 0,14881652 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12840527 0,14874487 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,12840527 0,14867329 ! muscle cell development GO:0055001 49 32 0,000 0,12840527 0,14860177 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12840527 0,14853033 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12840527 0,14845896 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,12840527 0,14838765 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,12840527 0,14831641 ! ovulation cycle GO:0042698 51 32 0,000 0,12840527 0,14824524 ! hindbrain development GO:0030902 61 32 0,000 0,12840527 0,14817414 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12840527 0,14810311 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12840527 0,14803215 ! gene silencing GO:0016458 65 32 0,000 0,12840527 0,14796125 ! post-embryonic development GO:0009791 69 33 0,000 0,13214254 0,15219481 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13214254 0,15212199 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13214254 0,15204924 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13214254 0,15197656 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13214254 0,15190394 ! cell fate specification GO:0001708 52 33 0,000 0,13214254 0,1518314 ! sterol transport GO:0015918 57 33 0,000 0,13214254 0,15175893 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13214254 0,15168653 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13214254 0,15161419 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13214254 0,15154192 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13214254 0,15146973 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,13586391 0,15566122 ! glial cell differentiation GO:0010001 63 34 0,000 0,13586391 0,15558713 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13586391 0,15551311 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13586391 0,15543917 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13586391 0,15536529 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13586391 0,15529148 ! spermatid development GO:0007286 63 34 0,000 0,13586391 0,15521774 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13586391 0,15514407 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13586391 0,15507048 ! placenta development GO:0001890 53 34 0,000 0,13586391 0,15499695 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,13586391 0,15492349 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,13956944 0,15907346 ! negative regulation of secretion GO:0051048 63 35 0,000 0,13956944 0,15899814 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,13956944 0,1589229 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,13956944 0,15884772 ! odontogenesis GO:0042476 66 35 0,000 0,13956944 0,15877261 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,13956944 0,15869758 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,13956944 0,15862262 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,13956944 0,15854772 ! cytokine production GO:0001816 59 35 0,000 0,13956944 0,1584729 ! vesicle localization GO:0051648 64 35 0,000 0,13956944 0,15839815 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,14325921 0,16250903 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14325921 0,16243245 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14325921 0,16235594 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14325921 0,1622795 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14325921 0,16220313 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14325921 0,16212684 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14325921 0,16205061 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14325921 0,16197446 ! aerobic respiration GO:0009060 55 36 0,000 0,14325921 0,16189838 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,14325921 0,16182237 ! embryonic organ development GO:0048568 57 36 0,000 0,14325921 0,16174644 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14325921 0,16167057 ! RNA export from nucleus GO:0006405 56 37 0,000 0,14693327 0,16573908 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,14693327 0,16566141 ! meiosis I GO:0007127 65 37 0,000 0,14693327 0,16558382 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,14693327 0,1655063 ! sister chromatid segregation GO:0000819 58 37 0,000 0,14693327 0,16542885 ! actomyosin structure organization GO:0031032 62 37 0,000 0,14693327 0,16535148 ! organic anion transport GO:0015711 68 37 0,000 0,14693327 0,16527417 ! tissue remodeling GO:0048771 76 37 0,000 0,14693327 0,16519694 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,14693327 0,16511978 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,14693327 0,1650427 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,14693327 0,16496568 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,14693327 0,16488874 ! pigment metabolic process GO:0042440 80 37 0,000 0,14693327 0,16481187 ! spermatid differentiation GO:0048515 66 37 0,000 0,14693327 0,16473507 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15059171 0,1687581 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,15059171 0,16867954 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15059171 0,16860104 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15059171 0,16852262 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15059171 0,16844428 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,15059171 0,168366 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,15059171 0,1682878 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15059171 0,16820968 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,15059171 0,16813162 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15059171 0,16805364 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15059171 0,16797573 ! glucan metabolic process GO:0044042 62 38 0,000 0,15059171 0,16789789 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,15423457 0,17187975 ! learning GO:0007612 77 39 0,000 0,15423457 0,17180017 ! organic ether metabolic process GO:0018904 55 39 0,000 0,15423457 0,17172067 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,15423457 0,17164124 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15423457 0,17156189 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15423457 0,17148261 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15423457 0,1714034 ! RNA modification GO:0009451 57 39 0,000 0,15423457 0,17132427 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15423457 0,17124521 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,15786193 0,17519179 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,15786193 0,17511102 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,15786193 0,17503032 ! feeding behavior GO:0007631 59 40 0,000 0,15786193 0,1749497 ! mesenchymal cell development GO:0014031 87 40 0,000 0,15786193 0,17486915 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,15786193 0,17478868 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16147385 0,17870565 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,16147385 0,17862349 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,16147385 0,1785414 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16147385 0,17845939 ! gliogenesis GO:0042063 88 41 0,000 0,16147385 0,17837745 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16147385 0,17829559 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,16147385 0,1782138 ! polyol metabolic process GO:0019751 66 41 0,000 0,16147385 0,17813209 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1650704 0,18201622 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,1650704 0,18193284 ! regulation of tube size GO:0035150 71 42 0,000 0,1650704 0,18184954 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1650704 0,18176631 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1650704 0,18168316 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1650704 0,18160009 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1650704 0,18151709 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1650704 0,18143417 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,1650704 0,18135132 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,16865165 0,18520121 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,16865165 0,18511673 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,16865165 0,18503231 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,16865165 0,18494798 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,16865165 0,18486372 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,16865165 0,18477954 ! striated muscle contraction GO:0006941 77 43 0,000 0,16865165 0,18469543 ! phagocytosis GO:0006909 90 43 0,000 0,16865165 0,1846114 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,16865165 0,18452745 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17221765 0,18834348 ! male sex differentiation GO:0046661 76 44 0,000 0,17221765 0,18825791 ! biopolymer methylation GO:0043414 84 44 0,000 0,17221765 0,18817242 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17221765 0,188087 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,17221765 0,18800166 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,17576847 0,1917909 ! glycolysis GO:0006096 65 45 0,000 0,17576847 0,19170396 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,17576847 0,1916171 ! leukocyte migration GO:0050900 68 45 0,000 0,17576847 0,19153032 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,17576847 0,19144361 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17576847 0,19135699 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17576847 0,19127044 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17576847 0,19118397 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,17576847 0,19109758 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17576847 0,19101127 ! cell growth GO:0016049 84 45 0,000 0,17576847 0,19092503 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,17930418 0,19467774 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,17930418 0,19458992 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,17930418 0,19450219 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18282484 0,19823189 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,18282484 0,1981426 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18282484 0,19805339 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18282484 0,19796425 ! JNK cascade GO:0007254 91 47 0,000 0,18282484 0,1978752 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,18282484 0,19778623 ! methylation GO:0032259 90 47 0,000 0,18282484 0,19769733 ! protein homooligomerization GO:0051260 76 47 0,000 0,18282484 0,19760852 ! Notch signaling pathway GO:0007219 96 48 0,000 0,18633052 0,20130724 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,18633052 0,20121688 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,18633052 0,20112661 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,18633052 0,20103642 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,18633052 0,20094631 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,18982127 0,20461916 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,18982127 0,20452753 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,18982127 0,20443597 ! regulation of ion transport GO:0043269 77 49 0,000 0,18982127 0,2043445 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,18982127 0,20425311 ! peptide metabolic process GO:0006518 76 49 0,000 0,18982127 0,20416181 ! response to temperature stimulus GO:0009266 76 49 0,000 0,18982127 0,20407058 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,18982127 0,20397944 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,18982127 0,20388838 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,18982127 0,2037974 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,19329716 0,20743664 ! neuromuscular process GO:0050905 99 50 0,000 0,19329716 0,20734416 ! regulation of ossification GO:0030278 117 50 0,000 0,19329716 0,20725176 ! inner ear development GO:0048839 79 50 0,000 0,19329716 0,20715945 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,19329716 0,20706721 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,19329716 0,20697506 ! viral infectious cycle GO:0019058 99 51 0,000 0,19675825 0,21058734 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,19675825 0,21049371 ! excretion GO:0007588 83 51 0,000 0,19675825 0,21040015 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,19675825 0,21030668 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,19675825 0,2102133 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,19675825 0,21011999 ! vesicle organization GO:0016050 107 51 0,000 0,19675825 0,21002677 ! regulation of cell shape GO:0008360 125 51 0,000 0,19675825 0,20993363 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,20020461 0,21351608 ! membrane fusion GO:0006944 110 52 0,000 0,20020461 0,21342148 ! positive regulation of growth GO:0045927 90 52 0,000 0,20020461 0,21332696 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,20020461 0,21323253 ! amino acid activation GO:0043038 92 52 0,000 0,20020461 0,21313818 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20363629 0,21669567 ! RNA catabolic process GO:0006401 93 53 0,000 0,20363629 0,21659987 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20363629 0,21650416 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,20363629 0,21640853 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20363629 0,21631299 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,20363629 0,21621753 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,20363629 0,21612215 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,20705336 0,21965185 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,20705336 0,21955504 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,20705336 0,21945832 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,20705336 0,21936169 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,20705336 0,21926514 ! chloride transport GO:0006821 90 55 0,000 0,21045589 0,22277029 ! glucose catabolic process GO:0006007 82 55 0,000 0,21045589 0,22267233 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,21045589 0,22257445 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,21045589 0,22247666 ! gastrulation GO:0007369 112 55 0,000 0,21045589 0,22237895 ! heart morphogenesis GO:0003007 97 55 0,000 0,21045589 0,22228133 ! RNA elongation GO:0006354 79 55 0,000 0,21045589 0,2221838 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,21045589 0,22208635 ! regulation of actin filament length GO:0030832 105 56 0,000 0,21384393 0,22556269 ! sensory perception of smell GO:0007608 80 56 0,000 0,21384393 0,22546384 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21384393 0,22536508 ! proton transport GO:0015992 94 56 0,000 0,21384393 0,22526641 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,21721754 0,22872009 ! hydrogen transport GO:0006818 97 58 0,000 0,22057678 0,23215562 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,22057678 0,23205411 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22057678 0,23195269 ! adult behavior GO:0030534 99 58 0,000 0,22057678 0,23185135 ! positive regulation of secretion GO:0051047 95 59 0,000 0,22392173 0,23526449 ! regulation of cellular component size GO:0032535 109 59 0,000 0,22392173 0,2351618 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22392173 0,23505919 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,22392173 0,23495668 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,22725242 0,23834757 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,22725242 0,23824372 ! regulation of heart contraction GO:0008016 110 60 0,000 0,22725242 0,23813995 ! camera-type eye development GO:0043010 116 60 0,000 0,22725242 0,23803628 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,22725242 0,23793269 ! kidney development GO:0001822 122 60 0,000 0,22725242 0,2378292 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,23056894 0,24119516 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,23056894 0,24109034 ! mesoderm development GO:0007498 119 61 0,000 0,23056894 0,2409856 ! tRNA processing GO:0008033 89 61 0,000 0,23056894 0,24088096 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,23056894 0,24077642 ! viral reproductive process GO:0022415 126 62 0,000 0,23387133 0,24411905 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,23387133 0,24401319 ! regulation of mitosis GO:0007088 105 63 0,000 0,23715965 0,24733685 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,23715965 0,24722969 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,23715965 0,24712262 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,23715965 0,24701564 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,23715965 0,24690875 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,24043397 0,2502094 ! cell redox homeostasis GO:0045454 102 64 0,000 0,24043397 0,25010122 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,24043397 0,24999314 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,24043397 0,24988515 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,24043397 0,24977726 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24369434 0,25305507 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,24369434 0,2529459 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,24369434 0,25283682 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,24694083 0,25609467 ! secondary metabolic process GO:0019748 116 66 0,000 0,24694083 0,25598433 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,25017349 0,25922369 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,25017349 0,2591121 ! activation of MAPK activity GO:0000187 115 67 0,000 0,25017349 0,25900061 ! chromosome segregation GO:0007059 113 67 0,000 0,25017349 0,25888921 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,25017349 0,25877791 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,25017349 0,2586667 ! hexose catabolic process GO:0019320 104 67 0,000 0,25017349 0,25855559 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,25017349 0,25844458 ! adaptive immune response GO:0002250 119 67 0,000 0,25017349 0,25833366 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,25017349 0,25822283 ! amino acid transport GO:0006865 125 68 0,000 0,25339238 0,26143313 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,25339238 0,26132107 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,25339238 0,26120911 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,25339238 0,26109724 ! viral reproduction GO:0016032 134 68 0,000 0,25339238 0,26098547 ! urogenital system development GO:0001655 137 69 0,000 0,25659756 0,26417361 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,25659756 0,26406062 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,25659756 0,26394772 ! antigen processing and presentation GO:0019882 104 69 0,000 0,25659756 0,26383492 ! amine catabolic process GO:0009310 117 71 0,000 0,26296701 0,27026853 ! humoral immune response GO:0006959 109 71 0,000 0,26296701 0,27015313 ! regulation of immune effector process GO:0002697 137 71 0,000 0,26296701 0,27003782 ! acute inflammatory response GO:0002526 113 72 0,000 0,2661314 0,27317071 ! regulation of blood pressure GO:0008217 125 73 0,000 0,26928231 0,27628709 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,26928231 0,27616932 ! fertilization GO:0009566 90 73 0,000 0,26928231 0,27605165 ! transition metal ion transport GO:0000041 126 74 0,000 0,27241979 0,27914907 ! neurotransmitter transport GO:0006836 123 74 0,000 0,27241979 0,27903023 ! exocytosis GO:0006887 133 74 0,000 0,27241979 0,2789115 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,27241979 0,27879286 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,27241979 0,27867433 ! eye development GO:0001654 143 74 0,000 0,27241979 0,27855589 ! organelle localization GO:0051640 136 74 0,000 0,27241979 0,27843756 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,27554391 0,2815111 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,27554391 0,28139161 ! rhythmic process GO:0048511 128 75 0,000 0,27554391 0,28127223 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,27865471 0,28432708 ! defense response to bacterium GO:0042742 89 76 0,000 0,27865471 0,28420655 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,27865471 0,28408612 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,27865471 0,2839658 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,28175227 0,28700083 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,28175227 0,28687937 ! blood coagulation GO:0007596 146 78 0,000 0,28483662 0,28989717 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,28483662 0,28977459 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,28483662 0,28965212 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,28790783 0,29265156 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,28790783 0,29252797 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,28790783 0,29240449 ! muscle cell differentiation GO:0042692 159 80 0,000 0,29096595 0,29538569 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,29096595 0,29526111 ! inorganic anion transport GO:0015698 138 80 0,000 0,29096595 0,29513663 ! digestion GO:0007586 112 81 0,000 0,29401104 0,29809969 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,29704316 0,30104711 ! hemostasis GO:0007599 158 84 0,000 0,30306867 0,30702452 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,30306867 0,3068953 ! nucleosome assembly GO:0006334 122 85 0,000 0,30606219 0,30979622 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,30904294 0,3126818 ! chromatin assembly GO:0031497 124 86 0,000 0,30904294 0,31255036 ! alcohol catabolic process GO:0046164 130 86 0,000 0,30904294 0,31241904 ! amine transport GO:0015837 155 86 0,000 0,30904294 0,31228782 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,31201099 0,31515467 ! cellular respiration GO:0045333 135 88 0,000 0,31496638 0,31800635 ! regulation of neurological system process GO:0031644 148 88 0,000 0,31496638 0,31787295 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,31496638 0,31773967 ! cellular defense response GO:0006968 114 89 0,000 0,31790918 0,32057397 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,31790918 0,32043967 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,32083944 0,32325783 ! sterol metabolic process GO:0016125 152 91 0,000 0,3237572 0,32606104 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,3237572 0,32592462 ! regulation of defense response GO:0031347 149 92 0,000 0,32666253 0,32871186 ! nucleosome organization GO:0034728 138 92 0,000 0,32666253 0,32857443 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,32666253 0,32843713 ! vitamin metabolic process GO:0006766 139 92 0,000 0,32666253 0,32829994 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,32955547 0,33106909 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,33243608 0,33382354 ! female pregnancy GO:0007565 164 94 0,000 0,33243608 0,33368427 ! forebrain development GO:0030900 188 95 0,000 0,3353044 0,33642302 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,3353044 0,33628278 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,3381605 0,3390059 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,3381605 0,33886471 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,34100442 0,34157229 ! hormone metabolic process GO:0042445 157 97 0,000 0,34100442 0,34143014 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,34383621 0,34412227 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,34383621 0,34397918 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,34665593 0,34665593