pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6367-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycine biosynthetic process GO:0006545 7 5 3,000 1,217E-09 2,973E-06 ! response to UV GO:0009411 120 55 5,000 9,021E-08 1,102E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 5,000 1,122E-07 9,135E-05 ! serine family amino acid biosynthetic process GO:0009070 19 14 3,000 2,369E-07 1,447E-04 ! negative regulation of DNA metabolic process GO:0051053 65 35 4,000 2,795E-07 1,365E-04 ! glycine metabolic process GO:0006544 30 18 3,000 7,153E-07 2,912E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 1,019E-06 3,555E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 1,019E-06 3,11E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 1,139E-06 3,092E-04 ! collagen catabolic process GO:0030574 29 21 3,000 1,386E-06 3,386E-04 ! regulation of helicase activity GO:0051095 16 7 2,000 2,159E-06 4,796E-04 ! regulation of DNA metabolic process GO:0051052 188 97 5,000 2,68E-06 5,455E-04 ! negative regulation of DNA replication GO:0008156 45 25 3,000 2,893E-06 5,437E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 3,445E-06 6,011E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 3,445E-06 5,611E-04 ! multicellular organismal catabolic process GO:0044243 38 27 3,000 3,989E-06 6,091E-04 ! cell junction assembly GO:0034329 85 31 3,000 7,064E-06 1,015E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 7,339E-06 9,96E-04 ! collagen metabolic process GO:0032963 49 32 3,000 8,048E-06 1,035E-03 ! serine family amino acid metabolic process GO:0009069 56 34 3,000 1,032E-05 1,26E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 3,000 1,161E-05 1,351E-03 ! cell junction organization GO:0034330 96 37 3,000 1,455E-05 1,616E-03 ! response to X-ray GO:0010165 28 13 2,000 1,734E-05 1,842E-03 ! mammary gland development GO:0030879 93 40 3,000 1,995E-05 2,031E-03 ! response to gamma radiation GO:0010332 30 14 2,000 2,2E-05 2,15E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 2,2E-05 2,067E-03 ! multicellular organismal metabolic process GO:0044236 64 41 3,000 2,204E-05 1,994E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 3,365E-05 2,936E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 4,144E-05 3,491E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 4,778E-05 3,891E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 4,875E-05 3,842E-03 ! cellular amino acid biosynthetic process GO:0008652 80 52 3,000 5,695E-05 4,348E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 2,000 5,772E-05 4,273E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 6,77E-05 4,865E-03 ! regulation of protein catabolic process GO:0042176 126 56 3,000 7,631E-05 5,327E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 7,631E-05 5,179E-03 ! hindlimb morphogenesis GO:0035137 47 22 2,000 9,093E-05 6,004E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 9,093E-05 5,846E-03 ! cell aging GO:0007569 48 22 2,000 9,093E-05 5,696E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,188E-04 7,256E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,346E-04 8,021E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,517E-04 8,825E-03 ! embryonic limb morphogenesis GO:0030326 139 67 3,000 1,539E-04 8,745E-03 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of helicase activity GO:0051096 12 5 1,000 1,572E-04 8,73E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 1,572E-04 8,536E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,572E-04 8,351E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,572E-04 8,173E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,572E-04 8,003E-03 ! microvillus organization GO:0032528 8 5 1,000 1,572E-04 7,84E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,572E-04 7,683E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,572E-04 7,532E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,572E-04 7,387E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,572E-04 7,248E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,572E-04 7,114E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,702E-04 7,56E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 1,901E-04 8,291E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 1,901E-04 8,146E-03 ! appendage morphogenesis GO:0035107 150 72 3,000 2,034E-04 8,569E-03 GO:0035108|limb morphogenesis, ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,114E-04 8,752E-03 ! appendage development GO:0048736 151 73 3,000 2,146E-04 8,737E-03 GO:0060173|limb development, ! response to UV-C GO:0010225 14 6 1,000 2,352E-04 9,421E-03 ! negative regulation of multicellular organism growth GO:0040015 9 6 1,000 2,352E-04 9,269E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,352E-04 9,122E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 2,352E-04 8,98E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,352E-04 8,841E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 2,585E-04 9,569E-03 ! regulation of catabolic process GO:0009894 173 77 3,000 2,635E-04 9,608E-03 ! response to mechanical stimulus GO:0009612 60 32 2,000 2,844E-04 0,01021794 ! BMP signaling pathway GO:0030509 71 32 2,000 2,844E-04 0,01006985 ! response to ionizing radiation GO:0010212 74 33 2,000 3,119E-04 0,01088673 ! negative regulation of protein transport GO:0051224 74 33 2,000 3,119E-04 0,0107334 ! response to hypoxia GO:0001666 178 81 3,000 3,2E-04 0,0108574 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 3,285E-04 0,01099261 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,285E-04 0,01084406 ! neuron adhesion GO:0007158 14 7 1,000 3,285E-04 0,01069947 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 3,285E-04 0,01055869 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,285E-04 0,01042156 ! negative regulation of DNA recombination GO:0045910 16 7 1,000 3,285E-04 0,01028795 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 3,285E-04 0,01015773 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 3,285E-04 0,01003075 ! centrosome duplication GO:0051298 14 7 1,000 3,285E-04 9,907E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 3,285E-04 9,786E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,285E-04 9,668E-03 ! transcription from RNA polymerase I promoter GO:0006360 14 7 1,000 3,285E-04 9,553E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,285E-04 9,441E-03 ! transcription termination GO:0006353 14 7 1,000 3,285E-04 9,331E-03 ! axonal fasciculation GO:0007413 19 7 1,000 3,285E-04 9,224E-03 ! response to oxygen levels GO:0070482 183 83 3,000 3,513E-04 9,751E-03 ! negative regulation of growth GO:0045926 168 85 3,000 3,847E-04 0,01055854 ! regulation of neuron differentiation GO:0045664 187 85 3,000 3,847E-04 0,01044123 ! male meiosis GO:0007140 9 8 1,000 4,368E-04 0,01172683 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 4,368E-04 0,01159937 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,368E-04 0,01147464 ! ER overload response GO:0006983 13 8 1,000 4,368E-04 0,01135257 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 1,000 4,368E-04 0,01123307 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 4,368E-04 0,01111606 ! response to tumor cell GO:0002347 16 8 1,000 4,368E-04 0,01100146 ! blastocyst growth GO:0001832 19 8 1,000 4,368E-04 0,0108892 ! amine biosynthetic process GO:0009309 146 88 3,000 4,389E-04 0,01083107 ! one-carbon metabolic process GO:0006730 167 88 3,000 4,389E-04 0,01072276 ! regulation of cAMP metabolic process GO:0030814 182 89 3,000 4,582E-04 0,01108198 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 4,753E-04 0,01138452 ! neural tube formation GO:0001841 79 38 2,000 4,753E-04 0,01127399 ! gland development GO:0048732 220 91 3,000 4,984E-04 0,01170833 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 5,412E-04 0,01259103 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,601E-04 0,01290984 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 5,601E-04 0,01278919 ! receptor clustering GO:0043113 20 9 1,000 5,601E-04 0,01267077 ! regulation of telomere maintenance GO:0032204 17 9 1,000 5,601E-04 0,01255452 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 3,000 5,864E-04 0,01302416 ! embryonic epithelial tube formation GO:0001838 85 41 2,000 5,954E-04 0,01310418 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 6,393E-04 0,01394544 ! T cell differentiation GO:0030217 93 42 2,000 6,393E-04 0,01382203 ! regulation of nucleotide metabolic process GO:0006140 197 98 3,000 6,593E-04 0,0141285 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 2,000 6,853E-04 0,01455774 ! neuron migration GO:0001764 85 43 2,000 6,853E-04 0,01443224 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 6,984E-04 0,01458181 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 6,984E-04 0,01445823 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 1,000 6,984E-04 0,01433674 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 6,984E-04 0,01421726 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 6,984E-04 0,01409977 ! multicellular organism growth GO:0035264 19 10 1,000 6,984E-04 0,01398419 ! motor axon guidance GO:0008045 22 10 1,000 6,984E-04 0,0138705 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 6,984E-04 0,01375864 ! double-strand break repair GO:0006302 85 44 2,000 7,333E-04 0,01433124 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 8,356E-04 0,01620104 ! pigmentation GO:0043473 103 46 2,000 8,356E-04 0,01607348 ! negative regulation of muscle development GO:0048635 27 11 1,000 8,513E-04 0,01624794 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 8,513E-04 0,01612199 ! detection of mechanical stimulus GO:0050982 22 11 1,000 8,513E-04 0,01599797 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 8,513E-04 0,01587585 ! regulation of intracellular pH GO:0051453 21 11 1,000 8,513E-04 0,01575558 ! oocyte development GO:0048599 20 11 1,000 8,513E-04 0,01563712 ! keratinocyte proliferation GO:0043616 19 11 1,000 8,513E-04 0,01552042 ! regulation of smoothened signaling pathway GO:0008589 27 11 1,000 8,513E-04 0,01540546 ! neural tube development GO:0021915 91 47 2,000 8,9E-04 0,01598651 ! response to insulin stimulus GO:0032868 98 47 2,000 8,9E-04 0,01586982 ! cellular component disassembly GO:0022411 89 48 2,000 9,465E-04 0,01675624 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,005E-03 0,01766906 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,019E-03 0,01777963 ! protein complex disassembly GO:0043241 28 12 1,000 1,019E-03 0,01765353 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,019E-03 0,01752921 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,019E-03 0,01740663 ! focal adhesion formation GO:0048041 37 12 1,000 1,019E-03 0,01728575 ! histone acetylation GO:0016573 27 12 1,000 1,019E-03 0,01716654 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,019E-03 0,01704896 ! oocyte differentiation GO:0009994 21 12 1,000 1,019E-03 0,01693298 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,019E-03 0,01681857 GO:0042130|negative regulation of T cell proliferation, ! localization within membrane GO:0051668 26 12 1,000 1,019E-03 0,01670569 ! activation of caspase activity GO:0006919 95 50 2,000 1,066E-03 0,01736776 ! response to estrogen stimulus GO:0043627 98 52 2,000 1,195E-03 0,01934035 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 1,195E-03 0,01921311 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 1,195E-03 0,01908753 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,201E-03 0,01905208 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 25 13 1,000 1,201E-03 0,01892916 ! membrane protein proteolysis GO:0033619 33 13 1,000 1,201E-03 0,01880782 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,201E-03 0,01868802 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 1,201E-03 0,01856974 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,263E-03 0,01941267 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 1,263E-03 0,01929134 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,334E-03 0,02024024 ! regulation of S phase GO:0033261 26 14 1,000 1,397E-03 0,02107447 ! cell-cell junction assembly GO:0007043 32 14 1,000 1,397E-03 0,02094518 ! bone mineralization GO:0030282 18 14 1,000 1,397E-03 0,02081747 ! regulation of cellular pH GO:0030641 27 14 1,000 1,397E-03 0,0206913 ! positive regulation of caspase activity GO:0043280 108 57 2,000 1,56E-03 0,02295589 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 2,000 1,56E-03 0,02281843 ! regulation of intracellular transport GO:0032386 108 57 2,000 1,56E-03 0,02268261 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,608E-03 0,02324852 ! regulation of mRNA processing GO:0050684 26 15 1,000 1,608E-03 0,02311176 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 1,608E-03 0,0229766 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,608E-03 0,02284302 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,608E-03 0,02271098 ! aging GO:0007568 112 58 2,000 1,64E-03 0,02302793 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 1,833E-03 0,02559166 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 1,833E-03 0,02544625 ! heterophilic cell adhesion GO:0007157 43 16 1,000 1,833E-03 0,02530249 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,833E-03 0,02516034 ! DNA replication initiation GO:0006270 28 16 1,000 1,833E-03 0,02501978 ! neuron recognition GO:0008038 40 16 1,000 1,833E-03 0,02488078 ! biomineral formation GO:0031214 22 16 1,000 1,833E-03 0,02474332 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 1,833E-03 0,02460737 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA damage response, signal transduction GO:0042770 136 62 2,000 1,987E-03 0,0265267 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 2,072E-03 0,02751309 ! signal complex assembly GO:0007172 47 17 1,000 2,072E-03 0,02736437 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,072E-03 0,02721725 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 2,072E-03 0,0270717 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 2,176E-03 0,02828078 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 2,176E-03 0,02813115 ! centrosome cycle GO:0007098 26 18 1,000 2,325E-03 0,02989644 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 2,325E-03 0,02973991 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 2,325E-03 0,02958502 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 2,325E-03 0,02943173 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 2,325E-03 0,02928002 ! negative regulation of cell growth GO:0030308 142 67 2,000 2,481E-03 0,03107775 ! extracellular matrix organization GO:0030198 146 68 2,000 2,588E-03 0,03225244 ! memory GO:0007613 34 19 1,000 2,592E-03 0,03214217 ! pigmentation during development GO:0048066 42 19 1,000 2,592E-03 0,03197984 ! neuromuscular junction development GO:0007528 43 19 1,000 2,592E-03 0,03181913 ! protein export from nucleus GO:0006611 40 19 1,000 2,592E-03 0,03166004 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 2,592E-03 0,03150253 ! negative regulation of cell size GO:0045792 144 69 2,000 2,697E-03 0,03262206 ! developmental maturation GO:0021700 128 69 2,000 2,697E-03 0,03246136 ! protein import into nucleus, docking GO:0000059 42 20 1,000 2,872E-03 0,03439797 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 2,872E-03 0,03423018 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,872E-03 0,03406401 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,872E-03 0,03389945 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,872E-03 0,03373647 ! forelimb morphogenesis GO:0035136 35 20 1,000 2,872E-03 0,03357505 ! response to alkaloid GO:0043279 38 20 1,000 2,872E-03 0,03341517 ! pancreas development GO:0031016 40 20 1,000 2,872E-03 0,03325681 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,872E-03 0,03309993 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 2,872E-03 0,03294453 ! cell-cell junction organization GO:0045216 43 20 1,000 2,872E-03 0,03279059 ! negative regulation of T cell activation GO:0050868 41 20 1,000 2,872E-03 0,03263807 ! cell cycle checkpoint GO:0000075 145 71 2,000 2,925E-03 0,03308724 ! actin filament organization GO:0007015 167 72 2,000 3,044E-03 0,03426713 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 3,044E-03 0,03410994 ! lipid phosphorylation GO:0046834 43 21 1,000 3,166E-03 0,0353223 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 3,166E-03 0,03516174 ! cellular macromolecular complex disassembly GO:0034623 44 21 1,000 3,166E-03 0,03500264 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 3,166E-03 0,03484497 ! collagen fibril organization GO:0030199 62 21 1,000 3,166E-03 0,03468872 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 3,166E-03 0,03453386 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,166E-03 0,03438037 ! regulation of caspase activity GO:0043281 136 74 2,000 3,289E-03 0,03555555 ! regulation of transcription factor activity GO:0051090 137 75 2,000 3,416E-03 0,03676709 GO:0090046|regulation of transcription regulator activity, ! axon guidance GO:0007411 162 75 2,000 3,416E-03 0,03660583 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 3,474E-03 0,03706082 ! glutamate signaling pathway GO:0007215 48 22 1,000 3,474E-03 0,03689969 ! cellular response to starvation GO:0009267 37 22 1,000 3,474E-03 0,03673995 ! apoptotic nuclear changes GO:0030262 34 22 1,000 3,474E-03 0,03658159 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,474E-03 0,03642459 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,474E-03 0,03626893 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 3,474E-03 0,03611459 ! protein stabilization GO:0050821 41 22 1,000 3,474E-03 0,03596156 ! learning or memory GO:0007611 161 76 2,000 3,546E-03 0,0365568 ! lymphocyte differentiation GO:0030098 193 76 2,000 3,546E-03 0,0364032 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 3,68E-03 0,03761132 ! regulation of DNA recombination GO:0000018 51 23 1,000 3,795E-03 0,03862896 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 3,795E-03 0,03846867 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 3,795E-03 0,03830971 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 3,955E-03 0,03975938 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 4,097E-03 0,04102013 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 4,129E-03 0,04117297 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,129E-03 0,0410056 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 4,129E-03 0,04083959 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 4,129E-03 0,04067491 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 4,129E-03 0,04051156 ! oogenesis GO:0048477 44 24 1,000 4,129E-03 0,04034951 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 4,129E-03 0,04018876 ! negative regulation of catabolic process GO:0009895 52 24 1,000 4,129E-03 0,04002928 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 4,242E-03 0,04096365 ! regulation of peptidase activity GO:0052547 150 82 2,000 4,391E-03 0,04222934 ! protein import into nucleus GO:0006606 174 82 2,000 4,391E-03 0,04206374 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 4,476E-03 0,04271853 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,476E-03 0,04255231 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,476E-03 0,04238738 ! leukocyte adhesion GO:0007159 55 25 1,000 4,476E-03 0,04222372 ! receptor metabolic process GO:0043112 53 25 1,000 4,476E-03 0,04206132 ! immunoglobulin production GO:0002377 62 25 1,000 4,476E-03 0,04190017 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 4,476E-03 0,04174025 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 4,542E-03 0,04219128 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 2,000 4,542E-03 0,04203147 ! T cell activation GO:0042110 189 84 2,000 4,697E-03 0,04329816 ! myelination GO:0042552 50 26 1,000 4,837E-03 0,0444225 ! microtubule organizing center organization GO:0031023 42 26 1,000 4,837E-03 0,04425612 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 4,837E-03 0,04409099 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 4,837E-03 0,04392708 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of cell development GO:0010721 83 26 1,000 4,837E-03 0,04376439 GO:0050768|negative regulation of neurogenesis, ! macromolecular complex disassembly GO:0032984 54 26 1,000 4,837E-03 0,04360289 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 4,837E-03 0,04344259 ! somatic diversification of immune receptors GO:0002200 63 26 1,000 4,837E-03 0,04328346 ! blastocyst development GO:0001824 50 26 1,000 4,837E-03 0,04312549 ! neural tube closure GO:0001843 58 26 1,000 4,837E-03 0,04296867 GO:0060606|tube closure, ! negative regulation of transport GO:0051051 164 85 2,000 4,854E-03 0,04296889 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 4,854E-03 0,04281377 ! mitochondrion organization GO:0007005 159 87 2,000 5,179E-03 0,04551611 ! regulation of protein transport GO:0051223 165 87 2,000 5,179E-03 0,04535297 GO:0070201|regulation of establishment of protein localization, ! tube lumen formation GO:0035148 59 27 1,000 5,21E-03 0,04545869 ! mitochondrial membrane organization GO:0007006 60 27 1,000 5,21E-03 0,04529691 ! response to starvation GO:0042594 47 27 1,000 5,21E-03 0,04513628 ! regulation of chromosome organization GO:0033044 49 27 1,000 5,21E-03 0,04497679 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,21E-03 0,04481842 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 5,21E-03 0,04466117 ! regulation of DNA binding GO:0051101 167 89 2,000 5,517E-03 0,04712882 ! tube morphogenesis GO:0035239 194 89 2,000 5,517E-03 0,0469646 ! protein localization in nucleus GO:0034504 192 89 2,000 5,517E-03 0,04680153 ! protein amino acid acylation GO:0043543 59 28 1,000 5,596E-03 0,04730736 ! fat cell differentiation GO:0045444 57 28 1,000 5,596E-03 0,04714423 ! base-excision repair GO:0006284 41 28 1,000 5,596E-03 0,04698222 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 5,596E-03 0,04682132 ! regulation of cell cycle process GO:0010564 161 90 2,000 5,691E-03 0,04745175 ! ossification GO:0001503 205 91 2,000 5,868E-03 0,04876132 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 5,995E-03 0,04964849 ! primary neural tube formation GO:0014020 61 29 1,000 5,995E-03 0,04948076 ! response to organic cyclic substance GO:0014070 58 29 1,000 5,995E-03 0,04931415 ! somitogenesis GO:0001756 52 29 1,000 5,995E-03 0,04914867 ! bone development GO:0060348 206 92 2,000 6,048E-03 0,049419 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 6,407E-03 0,05217202 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 6,407E-03 0,05199869 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 6,407E-03 0,05182651 ! iron ion homeostasis GO:0055072 60 31 1,000 6,831E-03 0,05507417 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 6,831E-03 0,054893 ! ensheathment of neurons GO:0007272 64 31 1,000 6,831E-03 0,05471303 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 6,831E-03 0,05453423 ! transcription initiation GO:0006352 171 97 2,000 6,999E-03 0,05569904 ! regulation of protein localization GO:0032880 188 97 2,000 6,999E-03 0,05551819 ! leukocyte differentiation GO:0002521 232 98 2,000 7,2E-03 0,05692145 ! spindle organization GO:0007051 50 32 1,000 7,267E-03 0,05726984 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 7,267E-03 0,05708569 ! peripheral nervous system development GO:0007422 68 32 1,000 7,267E-03 0,05690272 ! positive regulation of catabolic process GO:0009896 72 32 1,000 7,267E-03 0,05672093 ! skeletal muscle tissue development GO:0007519 223 100 2,000 7,61E-03 0,05920926 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 2,000 7,61E-03 0,05902129 ! regulation of pH GO:0006885 56 33 1,000 7,716E-03 0,05965152 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 7,716E-03 0,05946335 ! DNA damage checkpoint GO:0000077 78 35 1,000 8,65E-03 0,06645123 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 8,65E-03 0,06624292 ! calcium-mediated signaling GO:0019722 67 35 1,000 8,65E-03 0,06603591 ! regulation of muscle development GO:0048634 82 36 1,000 9,135E-03 0,0695214 ! negative regulation of DNA binding GO:0043392 67 36 1,000 9,135E-03 0,06930549 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 9,135E-03 0,06909092 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 9,632E-03 0,07262436 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 89 37 1,000 9,632E-03 0,0724009 ! female gonad development GO:0008585 71 37 1,000 9,632E-03 0,07217882 ! regulation of microtubule-based process GO:0032886 86 37 1,000 9,632E-03 0,07195808 ! negative regulation of cell activation GO:0050866 69 37 1,000 9,632E-03 0,0717387 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01014041 0,07529793 ! regulation of protein stability GO:0031647 77 38 1,000 0,01014041 0,07506976 ! negative regulation of binding GO:0051100 71 39 1,000 0,01066079 0,07868369 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01066079 0,07844669 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01066079 0,07821111 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01119275 0,08186794 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,01119275 0,08162356 ! mismatch repair GO:0006298 58 40 1,000 0,01119275 0,08138063 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01119275 0,08113915 ! maintenance of protein location GO:0045185 95 41 1,000 0,01173621 0,08482707 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01173621 0,08457684 ! ear morphogenesis GO:0042471 64 42 1,000 0,01229105 0,0883148 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01229105 0,08805581 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,01229105 0,08779834 ! cytokinesis GO:0000910 84 42 1,000 0,01229105 0,08754237 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01285718 0,09130843 GO:0090047|positive regulation of transcription regulator activity, ! glucose transport GO:0015758 66 43 1,000 0,01285718 0,09104377 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01285718 0,09078064 ! segmentation GO:0035282 78 43 1,000 0,01285718 0,09051902 ! hexose transport GO:0008645 68 44 1,000 0,01343451 0,09431182 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,01343451 0,09404159 ! B cell differentiation GO:0030183 124 45 1,000 0,01402294 0,09788011 ! female gamete generation GO:0007292 71 45 1,000 0,01402294 0,09760125 ! developmental growth GO:0048589 88 45 1,000 0,01402294 0,09732397 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01402294 0,09704827 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01462236 0,10091083 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01462236 0,10062657 ! mitochondrial transport GO:0006839 94 48 1,000 0,01585383 0,10879468 ! endosome transport GO:0016197 127 48 1,000 0,01585383 0,10848994 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01585383 0,10818689 ! response to calcium ion GO:0051592 94 49 1,000 0,01648568 0,11218529 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01648568 0,11187367 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,01648568 0,11156377 ! regulation of action potential GO:0001508 102 50 1,000 0,01712815 0,11559137 ! endocrine system development GO:0035270 109 50 1,000 0,01712815 0,11527294 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01778115 0,11933887 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,01778115 0,11901191 ! positive regulation of binding GO:0051099 88 52 1,000 0,01844458 0,12311504 ! histone modification GO:0016570 104 52 1,000 0,01844458 0,12277958 ! chromatin remodeling GO:0006338 122 53 1,000 0,01911835 0,12691882 ! cartilage development GO:0051216 99 53 1,000 0,01911835 0,12657486 ! synapse organization GO:0050808 102 53 1,000 0,01911835 0,12623277 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01980237 0,13039671 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01980237 0,13004618 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,01980237 0,12969754 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01981738 0,12944882 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01981738 0,12910363 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01981738 0,12876027 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01981738 0,12841873 ! neuron fate determination GO:0048664 7 5 0,000 0,01981738 0,128079 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01981738 0,12774106 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01981738 0,1274049 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01981738 0,1270705 ! polyol transport GO:0015791 12 5 0,000 0,01981738 0,12673785 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01981738 0,12640695 ! response to superoxide GO:0000303 10 5 0,000 0,01981738 0,12607776 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01981738 0,12575029 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01981738 0,12542451 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01981738 0,12510041 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01981738 0,12477799 ! female meiosis GO:0007143 10 5 0,000 0,01981738 0,12445722 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01981738 0,1241381 ! hypothalamus development GO:0021854 9 5 0,000 0,01981738 0,12382061 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01981738 0,12350475 ! cobalt ion transport GO:0006824 11 5 0,000 0,01981738 0,12319048 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01981738 0,12287782 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01981738 0,12256673 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01981738 0,12225722 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01981738 0,12194927 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01981738 0,12164287 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01981738 0,121338 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01981738 0,12103465 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01981738 0,12073282 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01981738 0,12043249 ! transposition GO:0032196 9 5 0,000 0,01981738 0,12013365 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01981738 0,11983629 ! negative chemotaxis GO:0050919 16 5 0,000 0,01981738 0,1195404 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01981738 0,11924596 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01981738 0,11895297 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01981738 0,11866142 ! behavioral response to pain GO:0048266 10 5 0,000 0,01981738 0,1183713 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01981738 0,11808259 ! Notch receptor processing GO:0007220 11 5 0,000 0,01981738 0,11779528 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01981738 0,11750937 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01981738 0,11722484 ! micturition GO:0060073 9 5 0,000 0,01981738 0,11694169 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01981738 0,1166599 ! copulation GO:0007620 9 5 0,000 0,01981738 0,11637947 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01981738 0,11610038 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01981738 0,11582263 ! bioluminescence GO:0008218 9 5 0,000 0,01981738 0,11554621 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01981738 0,1152711 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01981738 0,11499729 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01981738 0,11472479 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01981738 0,11445357 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01981738 0,11418363 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01981738 0,11391497 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01981738 0,11364756 ! grooming behavior GO:0007625 6 5 0,000 0,01981738 0,11338141 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01981738 0,1131165 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01981738 0,11285282 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01981738 0,11259037 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01981738 0,11232914 ! response to protozoan GO:0001562 13 5 0,000 0,01981738 0,11206912 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01981738 0,1118103 ! lymph vessel development GO:0001945 10 5 0,000 0,01981738 0,11155267 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01981738 0,11129623 ! endochondral ossification GO:0001958 17 5 0,000 0,01981738 0,11104096 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01981738 0,11078687 ! single strand break repair GO:0000012 8 5 0,000 0,01981738 0,11053393 ! parathyroid gland development GO:0060017 14 5 0,000 0,01981738 0,11028214 ! anagen GO:0042640 7 5 0,000 0,01981738 0,1100315 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01981738 0,109782 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01981738 0,10953362 ! cytokine secretion GO:0050663 15 5 0,000 0,01981738 0,10928637 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01981738 0,10904023 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01981738 0,10879519 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01981738 0,10855126 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01981738 0,10830841 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01981738 0,10806665 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01981738 0,10782597 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01981738 0,10758636 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01981738 0,10734781 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01981738 0,10711031 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01981738 0,10687386 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01981738 0,10663846 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01981738 0,10640409 ! valine metabolic process GO:0006573 12 5 0,000 0,01981738 0,10617075 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01981738 0,10593843 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01981738 0,10570712 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01981738 0,10547682 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01981738 0,10524752 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01981738 0,10501922 ! polyol catabolic process GO:0046174 9 5 0,000 0,01981738 0,10479191 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01981738 0,10456557 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01981738 0,10434022 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01981738 0,10411583 ! muscle cell migration GO:0014812 8 5 0,000 0,01981738 0,1038924 ! mitochondrial fission GO:0000266 8 5 0,000 0,01981738 0,10366994 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01981738 0,10344842 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01981738 0,10322785 ! mRNA transcription GO:0009299 10 5 0,000 0,01981738 0,10300821 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01981738 0,10278951 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01981738 0,10257174 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01981738 0,10235488 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01981738 0,10213895 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01981738 0,10192392 ! monocyte activation GO:0042117 10 5 0,000 0,01981738 0,10170979 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01981738 0,10149656 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01981738 0,10128423 ! response to food GO:0032094 6 5 0,000 0,01981738 0,10107278 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01981738 0,10086221 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01981738 0,10065252 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01981738 0,10044369 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01981738 0,10023574 ! forebrain neuron development GO:0021884 13 5 0,000 0,01981738 0,10002864 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01981738 0,09982239 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01981738 0,099617 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01981738 0,09941244 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01981738 0,09920873 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01981738 0,09900585 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01981738 0,0988038 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01981738 0,09860257 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01981738 0,09840216 ! lipid glycosylation GO:0030259 7 5 0,000 0,01981738 0,09820256 ! nucleobase transport GO:0015851 6 5 0,000 0,01981738 0,09800377 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01981738 0,09780578 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01981738 0,09760859 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01981738 0,09741219 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01981738 0,09721659 ! basic amino acid transport GO:0015802 12 5 0,000 0,01981738 0,09702176 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01981738 0,09682772 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01981738 0,09663445 ! actin nucleation GO:0045010 11 5 0,000 0,01981738 0,09644195 ! depurination GO:0045007 5 5 0,000 0,01981738 0,09625022 ! depyrimidination GO:0045008 10 5 0,000 0,01981738 0,09605925 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01981738 0,09586903 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01981738 0,09567957 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01981738 0,09549085 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01981738 0,09530287 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01981738 0,09511564 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01981738 0,09492914 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01981738 0,09474337 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01981738 0,09455832 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01981738 0,094374 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01981738 0,09419039 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01981738 0,0940075 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01981738 0,09382531 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01981738 0,09364383 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01981738 0,09346305 ! response to arsenic GO:0046685 11 5 0,000 0,01981738 0,09328297 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01981738 0,09310358 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01981738 0,09292488 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01981738 0,09274686 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01981738 0,09256952 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01981738 0,09239286 ! response to mercury ion GO:0046689 8 5 0,000 0,01981738 0,09221688 ! response to cadmium ion GO:0046686 7 5 0,000 0,01981738 0,09204156 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01981738 0,09186691 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01981738 0,09169292 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01981738 0,09151958 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01981738 0,09134691 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01981738 0,09117488 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01981738 0,0910035 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01981738 0,09083276 ! decidualization GO:0046697 11 5 0,000 0,01981738 0,09066266 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01981738 0,0904932 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01981738 0,09032437 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01981738 0,09015616 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01981738 0,08998859 ! embryonic cleavage GO:0040016 6 5 0,000 0,01981738 0,08982163 ! peroxisome fission GO:0016559 5 5 0,000 0,01981738 0,0896553 ! histone demethylation GO:0016577 13 5 0,000 0,01981738 0,08948958 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01981738 0,08932447 ! mitotic recombination GO:0006312 9 5 0,000 0,01981738 0,08915996 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01981738 0,08899607 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01981738 0,08883277 ! metaphase plate congression GO:0051310 7 5 0,000 0,01981738 0,08867007 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01981738 0,08850797 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01981738 0,08834646 ! enteric nervous system development GO:0048484 8 5 0,000 0,01981738 0,08818554 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01981738 0,0880252 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01981738 0,08786545 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01981738 0,08770627 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01981738 0,08754767 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01981738 0,08738964 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01981738 0,08723218 ! B cell homeostasis GO:0001782 13 5 0,000 0,01981738 0,08707529 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01981738 0,08691896 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01981738 0,08676319 ! metaphase GO:0051323 11 5 0,000 0,01981738 0,08660798 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01981738 0,08645332 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01981738 0,08629922 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01981738 0,08614566 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01981738 0,08599265 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01981738 0,08584018 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01981738 0,08568825 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01981738 0,08553686 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01981738 0,085386 ! response to redox state GO:0051775 6 5 0,000 0,01981738 0,08523567 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01981738 0,08508587 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01981738 0,0849366 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01981738 0,08478785 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01981738 0,08463962 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01981738 0,0844919 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01981738 0,0843447 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01981738 0,08419802 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01981738 0,08405184 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01981738 0,08390617 ! striatum development GO:0021756 14 5 0,000 0,01981738 0,083761 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01981738 0,08361634 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01981738 0,08347217 ! glial cell migration GO:0008347 10 5 0,000 0,01981738 0,0833285 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01981738 0,08318533 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01981738 0,08304264 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01981738 0,08290045 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01981738 0,08275874 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01981738 0,08261751 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01981738 0,08247676 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01981738 0,0823365 ! neuroprotection GO:0043526 8 5 0,000 0,01981738 0,08219671 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01981738 0,08205739 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01981738 0,08191855 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01981738 0,08178017 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01981738 0,08164226 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01981738 0,08150482 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01981738 0,08136783 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01981738 0,08123131 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01981738 0,08109524 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01981738 0,08095963 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01981738 0,08082447 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01981738 0,08068977 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01981738 0,08055551 ! spindle assembly GO:0051225 6 5 0,000 0,01981738 0,08042169 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01981738 0,08028833 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01981738 0,0801554 ! protein palmitoylation GO:0018345 12 5 0,000 0,01981738 0,08002291 ! drug metabolic process GO:0017144 7 5 0,000 0,01981738 0,07989086 ! stem cell division GO:0017145 11 5 0,000 0,01981738 0,07975924 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01981738 0,07962806 ! organ regeneration GO:0031100 7 5 0,000 0,01981738 0,07949731 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01981738 0,07936698 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01981738 0,07923709 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02049654 0,08181871 ! cell recognition GO:0008037 98 55 1,000 0,02049654 0,08168524 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,02049654 0,0815522 ! cell maturation GO:0048469 107 55 1,000 0,02049654 0,08141959 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02120078 0,08408037 ! muscle fiber development GO:0048747 131 57 1,000 0,021915 0,08677202 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,021915 0,08663162 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,0226391 0,08934947 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,0226391 0,08920536 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,0226391 0,08906171 ! maintenance of location GO:0051235 124 58 1,000 0,0226391 0,08891852 ! nuclear export GO:0051168 110 59 1,000 0,023373 0,09165367 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02373381 0,09291938 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02373381 0,09277071 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02373381 0,09262251 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02373381 0,09247479 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02373381 0,09232754 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02373381 0,09218075 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02373381 0,09203443 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02373381 0,09188858 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02373381 0,09174319 ! response to oxygen radical GO:0000305 11 6 0,000 0,02373381 0,09159825 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02373381 0,09145378 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02373381 0,09130975 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02373381 0,09116619 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02373381 0,09102307 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02373381 0,0908804 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02373381 0,09073817 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02373381 0,0905964 ! forebrain regionalization GO:0021871 9 6 0,000 0,02373381 0,09045506 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02373381 0,09031416 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02373381 0,09017371 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02373381 0,09003369 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02373381 0,0898941 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02373381 0,08975494 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02373381 0,08961622 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02373381 0,08947792 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02373381 0,08934005 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02373381 0,08920261 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02373381 0,08906558 ! malate metabolic process GO:0006108 13 6 0,000 0,02373381 0,08892898 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02373381 0,08879279 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02373381 0,08865702 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02373381 0,08852167 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02373381 0,08838673 ! protein refolding GO:0042026 15 6 0,000 0,02373381 0,0882522 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02373381 0,08811808 ! opsonization GO:0008228 8 6 0,000 0,02373381 0,08798436 ! mating behavior GO:0007617 7 6 0,000 0,02373381 0,08785105 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02373381 0,08771814 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02373381 0,08758564 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02373381 0,08745354 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02373381 0,08732183 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02373381 0,08719052 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02373381 0,0870596 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02373381 0,08692908 ! toxin metabolic process GO:0009404 11 6 0,000 0,02373381 0,08679894 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02373381 0,0866692 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02373381 0,08653984 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02373381 0,08641087 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02373381 0,08628228 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02373381 0,08615408 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02373381 0,08602625 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02373381 0,08589881 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02373381 0,08577174 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02373381 0,08564504 ! thymic T cell selection GO:0045061 16 6 0,000 0,02373381 0,08551872 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02373381 0,08539277 ! protein lipoylation GO:0009249 10 6 0,000 0,02373381 0,0852672 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02373381 0,08514199 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02373381 0,08501715 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02373381 0,08489267 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02373381 0,08476856 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02373381 0,08464481 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02373381 0,08452142 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02373381 0,08439839 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02373381 0,08427572 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02373381 0,0841534 ! hyperosmotic response GO:0006972 10 6 0,000 0,02373381 0,08403144 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02373381 0,08390983 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02373381 0,08378857 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02373381 0,08366767 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02373381 0,08354711 ! urea metabolic process GO:0019627 7 6 0,000 0,02373381 0,0834269 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02373381 0,08330703 ! neutrophil activation GO:0042119 7 6 0,000 0,02373381 0,08318751 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02373381 0,08306833 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02373381 0,08294949 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02373381 0,08283099 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02373381 0,08271283 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02373381 0,08259501 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02373381 0,08247752 ! neuron apoptosis GO:0051402 15 6 0,000 0,02373381 0,08236036 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02373381 0,08224354 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02373381 0,08212704 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02373381 0,08201088 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02373381 0,08189505 ! carnitine transport GO:0015879 10 6 0,000 0,02373381 0,08177954 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02373381 0,08166436 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02373381 0,0815495 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02373381 0,08143496 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02373381 0,08132075 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02373381 0,08120685 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02373381 0,08109328 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02373381 0,08098002 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02373381 0,08086708 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02373381 0,08075445 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02373381 0,08064213 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02373381 0,08053013 ! astrocyte development GO:0014002 16 6 0,000 0,02373381 0,08041844 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02373381 0,08030706 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02373381 0,08019598 ! interaction with symbiont GO:0051702 14 6 0,000 0,02373381 0,08008521 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02373381 0,07997475 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02373381 0,07986459 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02373381 0,07975474 ! response to copper ion GO:0046688 10 6 0,000 0,02373381 0,07964518 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02373381 0,07953593 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02373381 0,07942698 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02373381 0,07931832 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02373381 0,07920996 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02373381 0,0791019 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02373381 0,07899413 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02373381 0,07888666 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02373381 0,07877948 ! hair follicle maturation GO:0048820 8 6 0,000 0,02373381 0,07867258 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02373381 0,07856598 ! Schwann cell development GO:0014044 15 6 0,000 0,02373381 0,07845967 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02373381 0,07835364 ! response to pheromone GO:0019236 6 6 0,000 0,02373381 0,0782479 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02373381 0,07814244 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02373381 0,07803727 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02373381 0,07793238 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02373381 0,07782778 ! subpallium development GO:0021544 15 6 0,000 0,02373381 0,07772345 ! neural tube patterning GO:0021532 8 6 0,000 0,02373381 0,0776194 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02373381 0,07751563 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02373381 0,07741214 ! G2 phase GO:0051319 16 6 0,000 0,02373381 0,07730892 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02373381 0,07720598 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02373381 0,07710332 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02373381 0,07700092 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02373381 0,0768988 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02373381 0,07679695 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02373381 0,07669536 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02373381 0,07659405 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02373381 0,076493 ! receptor internalization GO:0031623 11 6 0,000 0,02373381 0,07639222 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02373381 0,0762917 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02373381 0,07619145 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02373381 0,07609146 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02373381 0,07599173 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02373381 0,07589227 ! protein deubiquitination GO:0016579 16 6 0,000 0,02373381 0,07579306 ! protein destabilization GO:0031648 9 6 0,000 0,02373381 0,07569412 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02373381 0,07559543 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02373381 0,075497 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02373381 0,07539882 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02373381 0,0753009 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02373381 0,07520323 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02373381 0,07510582 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02373381 0,07500866 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02373381 0,07491175 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02373381 0,07481509 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02373381 0,07471868 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02373381 0,07462251 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02373381 0,0745266 ! neural plate development GO:0001840 9 6 0,000 0,02373381 0,07443093 ! catecholamine transport GO:0051937 9 6 0,000 0,02373381 0,0743355 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02373381 0,07424032 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02373381 0,07414539 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02373381 0,07405069 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02373381 0,07395624 ! maternal placenta development GO:0001893 12 6 0,000 0,02373381 0,07386203 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02373381 0,07376806 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02373381 0,07367432 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02373381 0,07358083 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02373381 0,07348757 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02373381 0,07339455 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02373381 0,07330176 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02373381 0,07320921 GO:0055081|anion homeostasis, ! lipid modification GO:0030258 112 60 1,000 0,02411661 0,07429618 ! DNA catabolic process GO:0006308 94 60 1,000 0,02411661 0,0742026 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,02486983 0,0764239 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02563259 0,07866887 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,0264048 0,08093716 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,02718636 0,08322841 ! tRNA transcription GO:0009304 17 7 0,000 0,0276347 0,08449508 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,0276347 0,08438946 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,0276347 0,0842841 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0276347 0,08417901 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0276347 0,08407418 ! sleep GO:0030431 16 7 0,000 0,0276347 0,08396961 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0276347 0,0838653 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0276347 0,08376125 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0276347 0,08365745 ! prostate gland development GO:0030850 14 7 0,000 0,0276347 0,08355392 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0276347 0,08345064 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0276347 0,08334761 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0276347 0,08324484 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0276347 0,08314232 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0276347 0,08304006 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0276347 0,08293804 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0276347 0,08283628 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0276347 0,08273476 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0276347 0,0826335 ! glycolipid transport GO:0046836 11 7 0,000 0,0276347 0,08253248 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0276347 0,0824317 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0276347 0,08233118 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0276347 0,0822309 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0276347 0,08213086 ! mRNA stabilization GO:0048255 18 7 0,000 0,0276347 0,08203106 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,0276347 0,08193151 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0276347 0,0818322 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,0276347 0,08173313 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0276347 0,0816343 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0276347 0,08153571 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0276347 0,08143735 ! lipoprotein transport GO:0042953 14 7 0,000 0,0276347 0,08133924 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0276347 0,08124135 ! rhythmic behavior GO:0007622 17 7 0,000 0,0276347 0,08114371 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,0276347 0,0810463 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,0276347 0,08094912 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0276347 0,08085217 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0276347 0,08075546 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0276347 0,08065898 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0276347 0,08056273 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0276347 0,08046671 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,0276347 0,08037091 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0276347 0,08027535 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0276347 0,08018001 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0276347 0,08008489 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0276347 0,07999001 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0276347 0,07989534 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0276347 0,07980091 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0276347 0,07970669 ! spinal cord patterning GO:0021511 14 7 0,000 0,0276347 0,0796127 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0276347 0,07951892 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0276347 0,07942537 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0276347 0,07933204 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0276347 0,07923893 ! adrenal gland development GO:0030325 17 7 0,000 0,0276347 0,07914603 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0276347 0,07905336 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0276347 0,0789609 ! ovulation GO:0030728 10 7 0,000 0,0276347 0,07886865 ! adenohypophysis development GO:0021984 11 7 0,000 0,0276347 0,07877662 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0276347 0,07868481 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0276347 0,07859321 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0276347 0,07850182 ! microtubule nucleation GO:0007020 21 7 0,000 0,0276347 0,07841065 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0276347 0,07831968 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0276347 0,07822893 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0276347 0,07813839 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,0276347 0,07804805 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0276347 0,07795793 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0276347 0,07786801 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0276347 0,0777783 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0276347 0,0776888 ! galactose metabolic process GO:0006012 13 7 0,000 0,0276347 0,0775995 ! vesicle fusion GO:0006906 20 7 0,000 0,0276347 0,07751041 ! response to dietary excess GO:0002021 8 7 0,000 0,0276347 0,07742152 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0276347 0,07733284 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0276347 0,07724435 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0276347 0,07715608 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0276347 0,077068 ! organ growth GO:0035265 15 7 0,000 0,0276347 0,07698012 ! nucleoside transport GO:0015858 11 7 0,000 0,0276347 0,07689244 ! nucleoside salvage GO:0043174 11 7 0,000 0,0276347 0,07680497 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,0276347 0,07671769 ! male sex determination GO:0030238 15 7 0,000 0,0276347 0,07663061 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0276347 0,07654373 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,0276347 0,07645704 ! rRNA modification GO:0000154 14 7 0,000 0,0276347 0,07637055 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0276347 0,07628426 ! spindle checkpoint GO:0031577 16 7 0,000 0,0276347 0,07619816 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0276347 0,07611225 ! monocyte differentiation GO:0030224 16 7 0,000 0,0276347 0,07602654 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0276347 0,07594102 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0276347 0,07585569 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0276347 0,07577056 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0276347 0,07568561 ! fibrinolysis GO:0042730 11 7 0,000 0,0276347 0,07560086 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,0276347 0,07551629 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0276347 0,07543192 ! eating behavior GO:0042755 8 7 0,000 0,0276347 0,07534773 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0276347 0,07526373 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0276347 0,07517992 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0276347 0,07509629 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0276347 0,07501285 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0276347 0,0749296 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0276347 0,07484653 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0276347 0,07476364 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0276347 0,07468094 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0276347 0,07459842 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0276347 0,07451608 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0276347 0,07443392 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0276347 0,07435194 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0276347 0,07427015 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0276347 0,07418853 ! histone ubiquitination GO:0016574 9 7 0,000 0,0276347 0,0741071 ! regulation of meiosis GO:0040020 12 7 0,000 0,0276347 0,07402584 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0276347 0,07394476 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0276347 0,07386386 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0276347 0,07378313 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0276347 0,07370258 ! anaphase GO:0051322 18 7 0,000 0,0276347 0,07362221 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0276347 0,07354201 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,0276347 0,07346199 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0276347 0,07338214 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0276347 0,07330246 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,0276347 0,07322296 ! diuresis GO:0030146 12 7 0,000 0,0276347 0,07314363 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0276347 0,07306447 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0276347 0,07298548 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0276347 0,07290666 ! antibiotic transport GO:0042891 9 7 0,000 0,0276347 0,07282801 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0276347 0,07274953 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0276347 0,07267122 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0276347 0,07259308 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0276347 0,07251511 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0276347 0,0724373 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0276347 0,07235966 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0276347 0,07228219 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0276347 0,07220488 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0276347 0,07212774 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0276347 0,07205076 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0276347 0,07197395 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0276347 0,0718973 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0276347 0,07182081 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0276347 0,07174449 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0276347 0,07166833 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0276347 0,07159233 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0276347 0,07151649 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0276347 0,07144081 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0276347 0,07136529 ! muscle adaptation GO:0043500 13 7 0,000 0,0276347 0,07128993 ! embryonic heart tube development GO:0035050 14 7 0,000 0,0276347 0,07121473 ! retina homeostasis GO:0001895 12 7 0,000 0,0276347 0,07113969 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0276347 0,07106481 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0276347 0,07099008 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,0276347 0,07091551 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0276347 0,0708411 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,0279772 0,07164391 ! ear development GO:0043583 114 66 1,000 0,02877722 0,07361544 ! gonad development GO:0008406 115 66 1,000 0,02877722 0,07353844 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,03040449 0,07761564 ! detection of external stimulus GO:0009581 102 68 1,000 0,03040449 0,07753462 ! regulation of lipase activity GO:0060191 137 68 1,000 0,03040449 0,07745377 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,03040449 0,07737309 ! cell projection assembly GO:0030031 138 68 1,000 0,03040449 0,07729258 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,03123157 0,0793126 ! lung development GO:0030324 165 69 1,000 0,03123157 0,07923024 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,03123157 0,07914805 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,03123157 0,07906603 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03152011 0,0797139 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03152011 0,07963146 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03152011 0,0795492 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03152011 0,07946711 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03152011 0,07938518 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03152011 0,07930343 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03152011 0,07922184 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03152011 0,07914042 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03152011 0,07905916 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03152011 0,07897808 ! meiotic prophase I GO:0007128 14 8 0,000 0,03152011 0,07889716 ! response to zinc ion GO:0010043 12 8 0,000 0,03152011 0,0788164 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03152011 0,07873581 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03152011 0,07865539 ! oligopeptide transport GO:0006857 16 8 0,000 0,03152011 0,07857513 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03152011 0,07849503 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03152011 0,0784151 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03152011 0,07833533 ! signal peptide processing GO:0006465 12 8 0,000 0,03152011 0,07825572 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03152011 0,07817627 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03152011 0,07809698 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03152011 0,07801786 ! succinate metabolic process GO:0006105 17 8 0,000 0,03152011 0,07793889 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03152011 0,07786009 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03152011 0,07778144 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03152011 0,07770295 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03152011 0,07762462 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03152011 0,07754645 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03152011 0,07746844 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03152011 0,07739058 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03152011 0,07731288 ! reflex GO:0060004 17 8 0,000 0,03152011 0,07723533 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03152011 0,07715794 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03152011 0,07708071 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03152011 0,07700363 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03152011 0,0769267 ! pigment granule organization GO:0048753 17 8 0,000 0,03152011 0,07684993 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03152011 0,07677331 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03152011 0,07669684 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03152011 0,07662052 ! histidine catabolic process GO:0006548 10 8 0,000 0,03152011 0,07654436 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03152011 0,07646835 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03152011 0,07639249 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03152011 0,07631678 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03152011 0,07624121 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03152011 0,0761658 ! melanin metabolic process GO:0006582 17 8 0,000 0,03152011 0,07609054 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03152011 0,07601543 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03152011 0,07594046 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03152011 0,07586564 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03152011 0,07579097 ! macrophage activation GO:0042116 13 8 0,000 0,03152011 0,07571645 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03152011 0,07564207 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03152011 0,07556784 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03152011 0,07549375 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03152011 0,07541981 ! purine salvage GO:0043101 12 8 0,000 0,03152011 0,07534601 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03152011 0,07527236 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03152011 0,07519885 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03152011 0,07512549 ! osteoblast development GO:0002076 17 8 0,000 0,03152011 0,07505227 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03152011 0,07497919 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03152011 0,07490625 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03152011 0,07483346 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03152011 0,0747608 ! response to UV-B GO:0010224 17 8 0,000 0,03152011 0,07468829 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03152011 0,07461592 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03152011 0,07454368 ! intermediate filament organization GO:0045109 12 8 0,000 0,03152011 0,07447159 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03152011 0,07439964 ! cellular extravasation GO:0045123 13 8 0,000 0,03152011 0,07432782 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03152011 0,07425615 ! response to antibiotic GO:0046677 11 8 0,000 0,03152011 0,07418461 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03152011 0,07411321 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03152011 0,07404195 ! DNA topological change GO:0006265 12 8 0,000 0,03152011 0,07397082 ! response to tropane GO:0014073 15 8 0,000 0,03152011 0,07389983 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03152011 0,07382898 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03152011 0,07375826 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03152011 0,07368768 ! mast cell activation GO:0045576 14 8 0,000 0,03152011 0,07361723 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03152011 0,07354692 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03152011 0,07347674 ! gas homeostasis GO:0033483 14 8 0,000 0,03152011 0,0734067 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03152011 0,07333679 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03152011 0,07326701 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03152011 0,07319736 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03152011 0,07312785 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03152011 0,07305847 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03152011 0,07298922 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03152011 0,0729201 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03152011 0,07285111 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03152011 0,07278226 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03152011 0,07271353 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03152011 0,07264493 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03152011 0,07257646 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03152011 0,07250812 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03152011 0,07243991 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03152011 0,07237183 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03152011 0,07230387 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03152011 0,07223605 ! hormone catabolic process GO:0042447 17 8 0,000 0,03152011 0,07216835 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03152011 0,07210077 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03152011 0,07203333 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03152011 0,07196601 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03152011 0,07189881 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03152011 0,07183174 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03152011 0,0717648 ! adult feeding behavior GO:0008343 10 8 0,000 0,03152011 0,07169798 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03152011 0,07163128 ! ATP catabolic process GO:0006200 11 8 0,000 0,03152011 0,07156471 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03152011 0,07149826 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03152011 0,07143194 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03152011 0,07136573 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03152011 0,07129965 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03152011 0,0712337 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03152011 0,07116786 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03152011 0,07110215 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03152011 0,07103656 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03152011 0,07097108 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03152011 0,07090573 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03152011 0,0708405 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03152011 0,07077539 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03152011 0,0707104 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03152011 0,07064553 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03152011 0,07058078 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03152011 0,07051614 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03152011 0,07045163 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03152011 0,07038723 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03152011 0,07032295 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03152011 0,07025878 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,0320675 0,07141376 ! germ cell development GO:0007281 133 70 1,000 0,0320675 0,07134872 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,0320675 0,0712838 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,03291219 0,07309499 ! carbohydrate transport GO:0008643 114 72 1,000 0,03376558 0,07492217 ! respiratory tube development GO:0030323 171 72 1,000 0,03376558 0,07485418 ! B cell activation GO:0042113 179 72 1,000 0,03376558 0,07478631 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,03376558 0,07471857 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,03376558 0,07465095 ! axon extension GO:0048675 16 9 0,000 0,0353901 0,07817181 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0353901 0,0781012 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0353901 0,07803071 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0353901 0,07796035 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0353901 0,07789011 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0353901 0,07782 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0353901 0,07775002 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0353901 0,07768017 ! reproductive behavior GO:0019098 22 9 0,000 0,0353901 0,07761043 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0353901 0,07754083 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0353901 0,07747135 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0353901 0,07740199 ! UTP metabolic process GO:0046051 10 9 0,000 0,0353901 0,07733276 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0353901 0,07726365 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,0353901 0,07719466 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0353901 0,0771258 ! artery development GO:0060840 25 9 0,000 0,0353901 0,07705706 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0353901 0,07698845 ! regulation of glycolysis GO:0006110 20 9 0,000 0,0353901 0,07691995 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0353901 0,07685158 ! equilibrioception GO:0050957 20 9 0,000 0,0353901 0,07678333 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0353901 0,07671519 ! chemosensory behavior GO:0007635 21 9 0,000 0,0353901 0,07664718 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0353901 0,0765793 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0353901 0,07651153 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0353901 0,07644388 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0353901 0,07637635 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0353901 0,07630894 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0353901 0,07624164 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0353901 0,07617447 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0353901 0,07610742 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0353901 0,07604048 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0353901 0,07597366 ! protein targeting to ER GO:0045047 25 9 0,000 0,0353901 0,07590696 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0353901 0,07584037 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0353901 0,0757739 ! T cell selection GO:0045058 27 9 0,000 0,0353901 0,07570755 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0353901 0,07564132 ! glycine catabolic process GO:0006546 15 9 0,000 0,0353901 0,0755752 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0353901 0,07550919 ! endosome organization GO:0007032 20 9 0,000 0,0353901 0,0754433 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0353901 0,07537753 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0353901 0,07531187 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0353901 0,07524632 ! mannose metabolic process GO:0006013 13 9 0,000 0,0353901 0,07518089 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0353901 0,07511557 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0353901 0,07505037 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0353901 0,07498528 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0353901 0,0749203 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0353901 0,07485543 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0353901 0,07479068 ! retinol metabolic process GO:0042572 20 9 0,000 0,0353901 0,07472604 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0353901 0,07466151 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0353901 0,07459709 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0353901 0,07453278 ! macrophage differentiation GO:0030225 15 9 0,000 0,0353901 0,07446858 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0353901 0,0744045 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0353901 0,07434052 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0353901 0,07427665 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0353901 0,0742129 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0353901 0,07414925 ! response to amine stimulus GO:0014075 13 9 0,000 0,0353901 0,07408571 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0353901 0,07402228 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0353901 0,07395896 ! erythrocyte development GO:0048821 17 9 0,000 0,0353901 0,07389575 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0353901 0,07383264 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0353901 0,07376965 ! renal water homeostasis GO:0003091 15 9 0,000 0,0353901 0,07370676 ! postreplication repair GO:0006301 25 9 0,000 0,0353901 0,07364397 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0353901 0,0735813 ! icosanoid secretion GO:0032309 15 9 0,000 0,0353901 0,07351873 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0353901 0,07345627 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0353901 0,07339391 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0353901 0,07333166 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0353901 0,07326951 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0353901 0,07320747 ! sterol catabolic process GO:0016127 14 9 0,000 0,0353901 0,07314554 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0353901 0,07308371 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0353901 0,07302198 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0353901 0,07296036 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0353901 0,07289884 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0353901 0,07283743 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0353901 0,07277611 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0353901 0,07271491 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0353901 0,0726538 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0353901 0,0725928 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0353901 0,0725319 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0353901 0,0724711 ! purine base metabolic process GO:0006144 25 9 0,000 0,0353901 0,07241041 ! pigment granule transport GO:0051904 17 9 0,000 0,0353901 0,07234981 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0353901 0,07228932 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0353901 0,07222893 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0353901 0,07216863 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0353901 0,07210844 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0353901 0,07204835 ! mitochondrion localization GO:0051646 18 9 0,000 0,0353901 0,07198836 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,03549807 0,07214791 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,03549807 0,07208794 ! respiratory system development GO:0060541 175 74 1,000 0,03549807 0,07202807 ! reproductive structure development GO:0048608 131 75 1,000 0,03637703 0,07375027 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,03637703 0,07368911 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,03726434 0,07542401 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,03815993 0,07717278 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,03815993 0,07710895 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,03906373 0,07886999 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03924474 0,07917003 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03924474 0,07910471 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03924474 0,0790395 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03924474 0,07897439 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03924474 0,07890939 ! associative learning GO:0008306 21 10 0,000 0,03924474 0,0788445 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03924474 0,07877971 ! phosphate transport GO:0006817 24 10 0,000 0,03924474 0,07871503 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03924474 0,07865046 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03924474 0,07858599 ! CTP metabolic process GO:0046036 11 10 0,000 0,03924474 0,07852163 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03924474 0,07845737 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03924474 0,07839322 ! GTP metabolic process GO:0046039 11 10 0,000 0,03924474 0,07832917 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03924474 0,07826523 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03924474 0,07820139 ! social behavior GO:0035176 29 10 0,000 0,03924474 0,07813766 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03924474 0,07807403 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03924474 0,0780105 ! androgen metabolic process GO:0008209 17 10 0,000 0,03924474 0,07794708 ! phospholipid efflux GO:0033700 19 10 0,000 0,03924474 0,07788376 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03924474 0,07782054 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03924474 0,07775743 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03924474 0,07769442 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03924474 0,0776315 ! lung alveolus development GO:0048286 26 10 0,000 0,03924474 0,0775687 ! pathogenesis GO:0009405 17 10 0,000 0,03924474 0,07750599 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03924474 0,07744338 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03924474 0,07738088 ! endoderm development GO:0007492 18 10 0,000 0,03924474 0,07731847 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03924474 0,07725617 ! arginine catabolic process GO:0006527 17 10 0,000 0,03924474 0,07719397 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03924474 0,07713186 ! proline metabolic process GO:0006560 13 10 0,000 0,03924474 0,07706986 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03924474 0,07700796 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03924474 0,07694615 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03924474 0,07688445 ! V(D)J recombination GO:0033151 34 10 0,000 0,03924474 0,07682284 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03924474 0,07676134 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03924474 0,07669993 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03924474 0,07663862 ! B cell proliferation GO:0042100 19 10 0,000 0,03924474 0,0765774 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03924474 0,07651629 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03924474 0,07645527 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03924474 0,07639435 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03924474 0,07633353 ! ruffle organization GO:0031529 17 10 0,000 0,03924474 0,0762728 ! epithelial cell development GO:0002064 21 10 0,000 0,03924474 0,07621217 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03924474 0,07615163 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03924474 0,0760912 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03924474 0,07603086 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03924474 0,07597061 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03924474 0,07591046 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03924474 0,0758504 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,03924474 0,07579044 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03924474 0,07573058 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03924474 0,0756708 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03924474 0,07561113 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03924474 0,07555154 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03924474 0,07549205 ! segment specification GO:0007379 15 10 0,000 0,03924474 0,07543266 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03924474 0,07537336 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03924474 0,07531415 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03924474 0,07525503 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03924474 0,07519601 ! response to dsRNA GO:0043331 23 10 0,000 0,03924474 0,07513708 ! DNA ligation GO:0006266 18 10 0,000 0,03924474 0,07507824 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03924474 0,07501949 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03924474 0,07496084 ! melanosome localization GO:0032400 16 10 0,000 0,03924474 0,07490227 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03924474 0,0748438 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03924474 0,07478542 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03924474 0,07472713 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03924474 0,07466893 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03924474 0,07461082 ! induction of an organ GO:0001759 17 10 0,000 0,03924474 0,07455281 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03924474 0,07449488 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03924474 0,07443704 ! protein sumoylation GO:0016925 17 10 0,000 0,03924474 0,07437929 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03924474 0,07432163 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03924474 0,07426407 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03924474 0,07420659 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03924474 0,07414919 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03924474 0,07409189 ! salivary gland development GO:0007431 28 10 0,000 0,03924474 0,07403468 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03924474 0,07397755 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03924474 0,07392052 ! midbrain development GO:0030901 14 10 0,000 0,03924474 0,07386357 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03924474 0,0738067 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03924474 0,07374993 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03924474 0,07369324 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03924474 0,07363664 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03924474 0,07358013 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03924474 0,0735237 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03924474 0,07346736 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03924474 0,07341111 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03924474 0,07335494 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,03924474 0,07329886 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03924474 0,07324286 ! blastocyst formation GO:0001825 18 10 0,000 0,03924474 0,07318695 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03924474 0,07313113 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03924474 0,07307539 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03924474 0,07301973 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03924474 0,07296416 ! response to nicotine GO:0035094 20 10 0,000 0,03924474 0,07290868 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03924474 0,07285327 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03924474 0,07279796 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,03997565 0,07409751 ! protein oligomerization GO:0051259 149 79 1,000 0,03997565 0,07404133 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,04089562 0,07568787 ! meiosis GO:0007126 143 81 1,000 0,04182355 0,07734666 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 1,000 0,04275937 0,07901751 ! meiotic cell cycle GO:0051321 144 82 1,000 0,04275937 0,07895779 ! respiratory burst GO:0045730 17 11 0,000 0,04308409 0,0794973 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04308409 0,0794373 ! neuron fate specification GO:0048665 18 11 0,000 0,04308409 0,07937739 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04308409 0,07931758 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04308409 0,07925785 ! thyroid gland development GO:0030878 26 11 0,000 0,04308409 0,07919821 ! synapsis GO:0007129 14 11 0,000 0,04308409 0,07913867 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04308409 0,07907921 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04308409 0,07901984 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,04308409 0,07896056 ! response to pain GO:0048265 27 11 0,000 0,04308409 0,07890137 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04308409 0,07884227 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04308409 0,07878325 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04308409 0,07872433 ! bone resorption GO:0045453 16 11 0,000 0,04308409 0,07866549 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04308409 0,07860674 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04308409 0,07854808 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04308409 0,0784895 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04308409 0,07843102 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04308409 0,07837262 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04308409 0,0783143 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04308409 0,07825608 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04308409 0,07819794 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04308409 0,07813989 ! UV protection GO:0009650 20 11 0,000 0,04308409 0,07808192 ! adult heart development GO:0007512 16 11 0,000 0,04308409 0,07802404 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04308409 0,07796624 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04308409 0,07790853 ! macroautophagy GO:0016236 19 11 0,000 0,04308409 0,07785091 ! temperature homeostasis GO:0001659 18 11 0,000 0,04308409 0,07779337 ! behavioral fear response GO:0001662 27 11 0,000 0,04308409 0,07773591 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04308409 0,07767854 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04308409 0,07762126 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04308409 0,07756406 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04308409 0,07750694 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04308409 0,07744991 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04308409 0,07739296 ! regulation of organ growth GO:0046620 14 11 0,000 0,04308409 0,0773361 ! pigment granule localization GO:0051875 20 11 0,000 0,04308409 0,07727931 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04308409 0,07722262 ! vasoconstriction GO:0042310 20 11 0,000 0,04308409 0,077166 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04308409 0,07710947 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04308409 0,07705302 ! embryonic axis specification GO:0000578 19 11 0,000 0,04308409 0,07699665 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04308409 0,07694037 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04308409 0,07688417 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04308409 0,07682805 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04308409 0,07677201 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04308409 0,07671605 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04308409 0,07666018 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04308409 0,07660439 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04308409 0,07654867 ! prophase GO:0051324 17 11 0,000 0,04308409 0,07649304 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04308409 0,07643749 ! nucleosome positioning GO:0016584 15 11 0,000 0,04308409 0,07638202 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04308409 0,07632663 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04308409 0,07627132 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04308409 0,07621609 ! apical protein localization GO:0045176 18 11 0,000 0,04308409 0,07616094 ! acid secretion GO:0046717 20 11 0,000 0,04308409 0,07610588 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04308409 0,07605089 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04308409 0,07599597 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04308409 0,07594114 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04308409 0,07588639 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04308409 0,07583172 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04308409 0,07577712 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04308409 0,07572261 ! cholesterol efflux GO:0033344 21 11 0,000 0,04308409 0,07566817 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04308409 0,07561381 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04308409 0,07555953 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04308409 0,07550533 ! embryonic gut development GO:0048566 19 11 0,000 0,04308409 0,0754512 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04308409 0,07539715 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04308409 0,07534318 ! activation of innate immune response GO:0002218 16 11 0,000 0,04308409 0,07528929 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04308409 0,07523547 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04308409 0,07518173 ! lysogeny GO:0030069 22 11 0,000 0,04308409 0,07512807 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04308409 0,07507448 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04308409 0,07502097 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04308409 0,07496754 ! regulation of embryonic development GO:0045995 35 11 0,000 0,04308409 0,07491418 ! nucleus localization GO:0051647 22 11 0,000 0,04308409 0,0748609 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,04370301 0,07588234 ! response to drug GO:0042493 149 83 1,000 0,04370301 0,07582845 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,04370301 0,07577463 ! response to metal ion GO:0010038 158 84 1,000 0,04465438 0,07736926 ! response to nutrient GO:0007584 135 84 1,000 0,04465438 0,07731443 ! regulation of ligase activity GO:0051340 147 84 1,000 0,04465438 0,07725967 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,04561342 0,07886312 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,04658004 0,08047739 ! regulation of lyase activity GO:0051339 169 86 1,000 0,04658004 0,08042052 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,04658004 0,08036373 GO:0002696|positive regulation of leukocyte activation, ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0469082 0,08087278 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0469082 0,08081574 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0469082 0,08075879 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0469082 0,08070192 ! virus-host interaction GO:0019048 30 12 0,000 0,0469082 0,08064513 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0469082 0,08058841 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0469082 0,08053178 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0469082 0,08047523 ! hippocampus development GO:0021766 29 12 0,000 0,0469082 0,08041875 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0469082 0,08036236 ! T cell proliferation GO:0042098 32 12 0,000 0,0469082 0,08030604 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0469082 0,08024981 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0469082 0,08019365 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0469082 0,08013757 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0469082 0,08008157 ! drug transport GO:0015893 16 12 0,000 0,0469082 0,08002564 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0469082 0,0799698 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0469082 0,07991403 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0469082 0,07985834 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0469082 0,07980273 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0469082 0,0797472 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0469082 0,07969174 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0469082 0,07963636 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0469082 0,07958106 ! lipid digestion GO:0044241 21 12 0,000 0,0469082 0,07952583 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0469082 0,07947068 ! entry into host cell GO:0030260 34 12 0,000 0,0469082 0,07941561 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0469082 0,07936061 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0469082 0,07930569 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0469082 0,07925085 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0469082 0,07919608 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0469082 0,07914138 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0469082 0,07908677 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0469082 0,07903222 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0469082 0,07897776 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0469082 0,07892336 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0469082 0,07886905 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0469082 0,0788148 ! cranial nerve development GO:0021545 23 12 0,000 0,0469082 0,07876063 ! fucose catabolic process GO:0019317 25 12 0,000 0,0469082 0,07870654 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0469082 0,07865252 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0469082 0,07859858 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0469082 0,0785447 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0469082 0,07849091 ! zymogen activation GO:0031638 18 12 0,000 0,0469082 0,07843718 ! T cell homeostasis GO:0043029 28 12 0,000 0,0469082 0,07838353 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0469082 0,07832995 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0469082 0,07827645 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0469082 0,07822302 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0469082 0,07816966 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0469082 0,07811638 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0469082 0,07806316 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0469082 0,07801002 ! defense response to fungus GO:0050832 15 12 0,000 0,0469082 0,07795695 ! developmental induction GO:0031128 22 12 0,000 0,0469082 0,07790396 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0469082 0,07785103 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0469082 0,07779818 ! response to cold GO:0009409 17 12 0,000 0,0469082 0,0777454 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0469082 0,07769269 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0469082 0,07764006 ! response to inorganic substance GO:0010035 173 90 1,000 0,05052088 0,08356298 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,05052088 0,08350644 ! response to unfolded protein GO:0006986 139 90 1,000 0,05052088 0,08344998 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05071713 0,08371753 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05071713 0,08366101 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05071713 0,08360455 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05071713 0,08354818 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05071713 0,08349188 ! peroxisomal transport GO:0043574 28 13 0,000 0,05071713 0,08343566 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05071713 0,08337951 ! cartilage condensation GO:0001502 22 13 0,000 0,05071713 0,08332344 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05071713 0,08326744 ! organelle fusion GO:0048284 36 13 0,000 0,05071713 0,08321152 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05071713 0,08315567 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05071713 0,0830999 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05071713 0,0830442 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05071713 0,08298858 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05071713 0,08293303 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05071713 0,08287756 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05071713 0,08282216 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05071713 0,08276683 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05071713 0,08271158 ! methionine metabolic process GO:0006555 31 13 0,000 0,05071713 0,0826564 ! plasma membrane organization GO:0007009 27 13 0,000 0,05071713 0,0826013 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05071713 0,08254627 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05071713 0,08249131 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05071713 0,08243643 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05071713 0,08238161 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05071713 0,08232688 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05071713 0,08227221 ! exocrine system development GO:0035272 34 13 0,000 0,05071713 0,08221762 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05071713 0,0821631 ! monoamine transport GO:0015844 21 13 0,000 0,05071713 0,08210865 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,05071713 0,08205427 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,05071713 0,08199997 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05071713 0,08194573 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05071713 0,08189157 ! protein homotetramerization GO:0051289 24 13 0,000 0,05071713 0,08183748 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05071713 0,08178346 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05071713 0,08172952 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05071713 0,08167564 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05071713 0,08162184 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05071713 0,0815681 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05071713 0,08151444 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05071713 0,08146085 ! histone methylation GO:0016571 29 13 0,000 0,05071713 0,08140732 ! chromatin silencing GO:0006342 29 13 0,000 0,05071713 0,08135387 ! gland morphogenesis GO:0022612 31 13 0,000 0,05071713 0,08130049 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05071713 0,08124718 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05071713 0,08119394 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05071713 0,08114077 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05071713 0,08108766 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05071713 0,08103463 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05071713 0,08098167 ! spleen development GO:0048536 24 13 0,000 0,05071713 0,08092877 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05071713 0,08087595 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05071713 0,08082319 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05071713 0,0807705 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05071713 0,08071788 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05071713 0,08066533 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05071713 0,08061285 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05071713 0,08056043 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05071713 0,08050809 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05071713 0,08045581 ! insulin secretion GO:0030073 24 13 0,000 0,05071713 0,0804036 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05071713 0,08035146 ! acrosome reaction GO:0007340 19 13 0,000 0,05071713 0,08029938 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05071713 0,08024738 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05071713 0,08019544 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,05152432 0,08141908 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell adhesion GO:0030155 241 92 1,000 0,05253489 0,08296234 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,05355254 0,08451476 GO:0010498|proteasomal protein catabolic process, ! rRNA transcription GO:0009303 28 14 0,000 0,05451095 0,08597175 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05451095 0,08591629 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,05451095 0,08586089 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05451095 0,08580557 ! non-recombinational repair GO:0000726 29 14 0,000 0,05451095 0,08575032 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05451095 0,08569514 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05451095 0,08564003 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05451095 0,08558499 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05451095 0,08553002 ! lipid localization GO:0010876 32 14 0,000 0,05451095 0,08547513 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05451095 0,0854203 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,05451095 0,08536554 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05451095 0,08531086 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05451095 0,08525624 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05451095 0,08520169 ! arginine metabolic process GO:0006525 21 14 0,000 0,05451095 0,08514722 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05451095 0,08509281 ! regulation of heart rate GO:0002027 25 14 0,000 0,05451095 0,08503847 ! fear response GO:0042596 34 14 0,000 0,05451095 0,0849842 ! organic alcohol transport GO:0015850 29 14 0,000 0,05451095 0,08493 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05451095 0,08487587 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05451095 0,08482181 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05451095 0,08476782 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05451095 0,0847139 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05451095 0,08466004 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05451095 0,08460626 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05451095 0,08455254 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05451095 0,08449889 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05451095 0,08444531 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05451095 0,08439179 ! ribosome assembly GO:0042255 18 14 0,000 0,05451095 0,08433835 ! cerebellum development GO:0021549 23 14 0,000 0,05451095 0,08428497 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05451095 0,08423166 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05451095 0,08417841 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05451095 0,08412524 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05451095 0,08407213 ! NADP metabolic process GO:0006739 24 14 0,000 0,05451095 0,08401908 ! oxygen transport GO:0015671 22 14 0,000 0,05451095 0,08396611 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05451095 0,0839132 ! male genitalia development GO:0030539 26 14 0,000 0,05451095 0,08386036 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05451095 0,08380758 ! regulation of axon extension GO:0030516 43 14 0,000 0,05451095 0,08375487 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05451095 0,08370223 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05451095 0,08364965 ! regulation of membrane potential GO:0042391 179 94 1,000 0,05457718 0,08369872 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,05560875 0,08522722 ! sex differentiation GO:0007548 171 96 1,000 0,05664718 0,08676431 ! response to protein stimulus GO:0051789 158 96 1,000 0,05664718 0,08670994 ! regulation of T cell activation GO:0050863 175 96 1,000 0,05664718 0,08665565 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05828971 0,08911249 ! lactation GO:0007595 30 15 0,000 0,05828971 0,08905676 ! reproductive cellular process GO:0048610 22 15 0,000 0,05828971 0,0890011 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05828971 0,08894551 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05828971 0,08888999 ! superoxide anion generation GO:0042554 22 15 0,000 0,05828971 0,08883454 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05828971 0,08877916 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,05828971 0,08872384 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05828971 0,0886686 ! copper ion transport GO:0006825 22 15 0,000 0,05828971 0,08861342 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05828971 0,08855831 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05828971 0,08850327 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05828971 0,0884483 ! sulfate transport GO:0008272 27 15 0,000 0,05828971 0,0883934 ! response to cAMP GO:0051591 25 15 0,000 0,05828971 0,08833856 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05828971 0,0882838 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05828971 0,0882291 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05828971 0,08817447 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05828971 0,0881199 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05828971 0,08806541 ! vesicle coating GO:0006901 38 15 0,000 0,05828971 0,08801098 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05828971 0,08795662 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05828971 0,08790232 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05828971 0,0878481 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05828971 0,08779394 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05828971 0,08773984 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05828971 0,08768582 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05828971 0,08763186 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05828971 0,08757796 ! histone deacetylation GO:0016575 24 15 0,000 0,05828971 0,08752413 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05828971 0,08747037 ! water homeostasis GO:0030104 28 15 0,000 0,05828971 0,08741668 ! cofactor transport GO:0051181 30 15 0,000 0,05828971 0,08736305 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05828971 0,08730948 ! muscle maintenance GO:0046716 26 15 0,000 0,05828971 0,08725598 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05828971 0,08720255 ! intestinal absorption GO:0050892 31 15 0,000 0,05828971 0,08714918 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05828971 0,08709588 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05828971 0,08704264 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05828971 0,08698947 ! cell killing GO:0001906 32 15 0,000 0,05828971 0,08693636 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,05828971 0,08688332 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05828971 0,08683034 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05828971 0,08677743 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05828971 0,08672458 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05828971 0,0866718 ! actin filament polymerization GO:0030041 27 15 0,000 0,05828971 0,08661908 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05828971 0,08656642 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06205348 0,09210003 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06205348 0,09204411 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06205348 0,09198826 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06205348 0,09193247 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06205348 0,09187676 ! bone remodeling GO:0046849 28 16 0,000 0,06205348 0,09182111 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06205348 0,09176552 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06205348 0,09171001 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06205348 0,09165456 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06205348 0,09159918 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06205348 0,09154387 ! startle response GO:0001964 28 16 0,000 0,06205348 0,09148862 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06205348 0,09143344 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06205348 0,09137833 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06205348 0,09132328 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06205348 0,0912683 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06205348 0,09121339 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06205348 0,09115854 ! pituitary gland development GO:0021983 30 16 0,000 0,06205348 0,09110375 ! response to osmotic stress GO:0006970 27 16 0,000 0,06205348 0,09104904 ! lysosomal transport GO:0007041 31 16 0,000 0,06205348 0,09099439 ! fructose metabolic process GO:0006000 25 16 0,000 0,06205348 0,0909398 ! L-amino acid transport GO:0015807 33 16 0,000 0,06205348 0,09088528 ! stem cell development GO:0048864 46 16 0,000 0,06205348 0,09083082 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06205348 0,09077644 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06205348 0,09072211 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06205348 0,09066785 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06205348 0,09061366 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06205348 0,09055953 ! axon cargo transport GO:0008088 46 16 0,000 0,06205348 0,09050546 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06205348 0,09045146 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06205348 0,09039752 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06205348 0,09034365 ! tissue regeneration GO:0042246 27 16 0,000 0,06205348 0,09028984 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06205348 0,0902361 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06205348 0,09018242 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06205348 0,0901288 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06205348 0,09007525 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06205348 0,09002176 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06205348 0,08996834 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06205348 0,08991497 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06205348 0,08986168 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06205348 0,08980844 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06205348 0,08975527 ! peptide hormone processing GO:0016486 27 16 0,000 0,06205348 0,08970216 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06580231 0,09506507 ! metencephalon development GO:0022037 32 17 0,000 0,06580231 0,09500889 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06580231 0,09495277 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,06580231 0,09489672 ! filopodium assembly GO:0046847 42 17 0,000 0,06580231 0,09484073 ! endothelial cell migration GO:0043542 31 17 0,000 0,06580231 0,09478481 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06580231 0,09472895 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06580231 0,09467317 ! glial cell development GO:0021782 28 17 0,000 0,06580231 0,09461744 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06580231 0,09456179 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06580231 0,09450619 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06580231 0,09445067 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06580231 0,09439521 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06580231 0,09433981 ! myoblast differentiation GO:0045445 50 17 0,000 0,06580231 0,09428448 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,06580231 0,09422921 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,06580231 0,09417401 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,06580231 0,09411887 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06580231 0,0940638 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06580231 0,09400879 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06580231 0,09395385 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06580231 0,09389897 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06580231 0,09384415 ! membrane budding GO:0006900 42 17 0,000 0,06580231 0,0937894 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06580231 0,09373472 ! regulation of protein binding GO:0043393 33 17 0,000 0,06580231 0,09368009 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06580231 0,09362553 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06580231 0,09357103 ! genitalia development GO:0048806 32 17 0,000 0,06580231 0,0935166 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06580231 0,09346223 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06580231 0,09340792 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06580231 0,09335368 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06580231 0,0932995 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06580231 0,09324538 ! steroid catabolic process GO:0006706 34 17 0,000 0,06580231 0,09319133 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06580231 0,09313733 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06580231 0,0930834 ! gas transport GO:0015669 26 17 0,000 0,06580231 0,09302954 ! organic cation transport GO:0015695 32 17 0,000 0,06580231 0,09297573 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,06580231 0,09292199 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06580231 0,09286831 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06580231 0,09281469 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06953626 0,09802486 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06953626 0,09796833 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06953626 0,09791186 ! limbic system development GO:0021761 40 18 0,000 0,06953626 0,09785546 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06953626 0,09779912 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06953626 0,09774285 ! adult walking behavior GO:0007628 36 18 0,000 0,06953626 0,09768665 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06953626 0,0976305 ! heart looping GO:0001947 34 18 0,000 0,06953626 0,09757443 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06953626 0,09751841 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06953626 0,09746247 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06953626 0,09740658 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06953626 0,09735076 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06953626 0,097295 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06953626 0,09723931 ! response to retinoic acid GO:0032526 31 18 0,000 0,06953626 0,09718368 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06953626 0,09712812 ! DNA integration GO:0015074 32 18 0,000 0,06953626 0,09707262 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06953626 0,09701718 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06953626 0,0969618 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06953626 0,09690649 ! neural crest cell migration GO:0001755 41 18 0,000 0,06953626 0,09685124 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06953626 0,09679606 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06953626 0,09674093 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06953626 0,09668587 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06953626 0,09663088 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,06953626 0,09657594 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06953626 0,09652107 ! detection of bacterium GO:0016045 22 18 0,000 0,06953626 0,09646626 ! nerve development GO:0021675 34 18 0,000 0,06953626 0,09641151 ! defense response to virus GO:0051607 43 18 0,000 0,06953626 0,09635682 ! microspike assembly GO:0030035 46 18 0,000 0,06953626 0,0963022 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06953626 0,09624764 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06953626 0,09619314 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07325539 0,10128065 ! positive regulation of translation GO:0045727 31 19 0,000 0,07325539 0,10122337 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07325539 0,10116615 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,07325539 0,10110899 ! neuron maturation GO:0042551 46 19 0,000 0,07325539 0,1010519 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07325539 0,10099487 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,07325539 0,10093791 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07325539 0,10088101 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07325539 0,10082418 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07325539 0,10076741 ! inositol metabolic process GO:0006020 33 19 0,000 0,07325539 0,1007107 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07325539 0,10065406 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07325539 0,10059748 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07325539 0,10054096 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07325539 0,10048451 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07325539 0,10042812 ! cerebral cortex development GO:0021987 40 19 0,000 0,07325539 0,1003718 ! response to vitamin A GO:0033189 32 19 0,000 0,07325539 0,10031554 ! heme metabolic process GO:0042168 40 19 0,000 0,07325539 0,10025934 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07325539 0,1002032 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,07325539 0,10014713 ! response to fungus GO:0009620 26 19 0,000 0,07325539 0,10009112 ! peptide cross-linking GO:0018149 39 19 0,000 0,07325539 0,10003517 ! heart process GO:0003015 32 19 0,000 0,07325539 0,09997928 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07325539 0,09992346 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07325539 0,0998677 ! visual learning GO:0008542 38 19 0,000 0,07325539 0,099812 ! cellular pigmentation GO:0033059 37 19 0,000 0,07325539 0,09975636 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07325539 0,09970079 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07325539 0,09964528 ! vitamin transport GO:0051180 31 19 0,000 0,07325539 0,09958983 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07325539 0,09953444 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07325539 0,09947911 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07325539 0,09942384 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07325539 0,09936864 ! cilium assembly GO:0042384 38 19 0,000 0,07325539 0,09931349 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07325539 0,09925841 ! protein secretion GO:0009306 45 20 0,000 0,07695976 0,1042199 ! positive regulation of ossification GO:0045778 50 20 0,000 0,07695976 0,10416216 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,07695976 0,10410448 ! skin development GO:0043588 42 20 0,000 0,07695976 0,10404687 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07695976 0,10398932 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,07695976 0,10393184 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07695976 0,10387441 ! response to vitamin GO:0033273 36 20 0,000 0,07695976 0,10381706 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07695976 0,10375976 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,07695976 0,10370253 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,07695976 0,10364536 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07695976 0,10358826 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07695976 0,10353122 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07695976 0,10347424 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,07695976 0,10341732 ! body fluid secretion GO:0007589 33 20 0,000 0,07695976 0,10336047 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,07695976 0,10330368 ! peptide secretion GO:0002790 38 20 0,000 0,07695976 0,10324695 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07695976 0,10319028 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,07695976 0,10313368 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07695976 0,10307713 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07695976 0,10302065 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07695976 0,10296423 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,07695976 0,10290788 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07695976 0,10285158 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07695976 0,10279535 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07695976 0,10273918 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07695976 0,10268306 ! regulation of glucose import GO:0046324 30 20 0,000 0,07695976 0,10262701 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07695976 0,10257103 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,07695976 0,1025151 ! negative regulation of translation GO:0017148 32 20 0,000 0,07695976 0,10245923 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07695976 0,10240343 ! regulation of cell killing GO:0031341 46 21 0,000 0,08064943 0,10725452 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08064943 0,10719616 ! hormone secretion GO:0046879 39 21 0,000 0,08064943 0,10713787 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08064943 0,10707964 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08064943 0,10702148 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08064943 0,10696338 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08064943 0,10690534 ! ovarian follicle development GO:0001541 39 21 0,000 0,08064943 0,10684737 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08064943 0,10678946 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08064943 0,10673161 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08064943 0,10667382 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08064943 0,1066161 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08064943 0,10655844 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08064943 0,10650084 ! sensory perception of pain GO:0019233 33 21 0,000 0,08064943 0,1064433 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08064943 0,10638582 ! diencephalon development GO:0021536 36 21 0,000 0,08064943 0,10632841 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08064943 0,10627106 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08064943 0,10621377 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08064943 0,10615654 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08064943 0,10609938 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08064943 0,10604227 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08064943 0,10598523 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08064943 0,10592825 ! actin filament-based movement GO:0030048 47 21 0,000 0,08064943 0,10587133 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08432445 0,11063621 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08432445 0,11057682 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08432445 0,1105175 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08432445 0,11045824 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08432445 0,11039905 ! microtubule-based transport GO:0010970 59 22 0,000 0,08432445 0,11033992 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,08432445 0,11028085 ! vacuolar transport GO:0007034 41 22 0,000 0,08432445 0,11022184 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08432445 0,1101629 ! fucose metabolic process GO:0006004 44 22 0,000 0,08432445 0,11010402 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08432445 0,1100452 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08432445 0,10998645 ! ureteric bud development GO:0001657 50 22 0,000 0,08432445 0,10992776 ! stem cell differentiation GO:0048863 57 22 0,000 0,08432445 0,10986913 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08432445 0,10981057 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,08432445 0,10975206 ! cytolysis GO:0019835 27 22 0,000 0,08432445 0,10969362 ! renal system process GO:0003014 42 22 0,000 0,08432445 0,10963524 ! vasodilation GO:0042311 40 22 0,000 0,08432445 0,10957693 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08432445 0,10951867 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,08432445 0,10946048 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,08432445 0,10940235 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08432445 0,10934428 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08432445 0,10928627 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,08432445 0,10922833 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,08432445 0,10917044 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08432445 0,10911262 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08432445 0,10905486 ! sarcomere organization GO:0045214 32 22 0,000 0,08432445 0,10899716 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,08432445 0,10893952 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08432445 0,10888194 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08432445 0,10882442 ! gut development GO:0048565 44 22 0,000 0,08432445 0,10876696 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08432445 0,10870956 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,08432445 0,10865223 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08432445 0,10859495 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,08798488 0,11324924 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,08798488 0,11318961 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,08798488 0,11313003 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,08798488 0,11307052 ! gluconeogenesis GO:0006094 38 23 0,000 0,08798488 0,11301107 ! glycerol metabolic process GO:0006071 40 23 0,000 0,08798488 0,11295169 ! viral genome replication GO:0019079 44 23 0,000 0,08798488 0,11289237 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,08798488 0,1128331 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,08798488 0,11277391 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,08798488 0,11271477 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,08798488 0,11265569 ! regeneration GO:0031099 42 23 0,000 0,08798488 0,11259668 ! axis specification GO:0009798 43 23 0,000 0,08798488 0,11253773 ! visual behavior GO:0007632 46 23 0,000 0,08798488 0,11247884 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,08798488 0,11242001 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,08798488 0,11236125 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,08798488 0,11230254 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,08798488 0,1122439 ! peroxisome organization GO:0007031 43 23 0,000 0,08798488 0,11218531 ! lysosome organization GO:0007040 47 23 0,000 0,08798488 0,11212679 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,08798488 0,11206833 ! vesicle targeting GO:0006903 49 23 0,000 0,08798488 0,11200993 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,08798488 0,1119516 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,08798488 0,11189332 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,08798488 0,1118351 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,08798488 0,11177694 ! DNA modification GO:0006304 36 23 0,000 0,08798488 0,11171885 ! fatty acid transport GO:0015908 47 23 0,000 0,08798488 0,11166081 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,08798488 0,11160284 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,08798488 0,11154492 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,08798488 0,11148707 ! hormone transport GO:0009914 41 23 0,000 0,08798488 0,11142927 ! cell-cell recognition GO:0009988 28 23 0,000 0,08798488 0,11137154 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,08798488 0,11131386 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,08798488 0,11125624 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,08798488 0,11119869 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,09163078 0,11574664 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,09163078 0,11568682 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,09163078 0,11562707 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,09163078 0,11556738 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,09163078 0,11550774 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,09163078 0,11544817 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,09163078 0,11538866 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,09163078 0,11532921 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,09163078 0,11526983 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,09163078 0,1152105 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,09163078 0,11515124 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,09163078 0,11509203 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,09163078 0,11503289 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,09163078 0,11497381 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,09163078 0,11491479 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,09163078 0,11485583 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,09163078 0,11479693 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,09163078 0,11473809 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,09163078 0,11467931 ! membrane depolarization GO:0051899 45 24 0,000 0,09163078 0,11462059 ! pallium development GO:0021543 56 24 0,000 0,09163078 0,11456193 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,09163078 0,11450333 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,09163078 0,11444479 ! platelet activation GO:0030168 41 24 0,000 0,09163078 0,11438631 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,09163078 0,11432789 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,09163078 0,11426953 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,09163078 0,11421123 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,09163078 0,11415299 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,09163078 0,1140948 ! regulation of amine transport GO:0051952 41 24 0,000 0,09163078 0,11403668 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,09163078 0,11397862 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,09526222 0,11843542 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,09526222 0,11837517 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,09526222 0,11831499 ! phototransduction GO:0007602 37 25 0,000 0,09526222 0,11825487 ! keratinization GO:0031424 37 25 0,000 0,09526222 0,11819482 ! vasculogenesis GO:0001570 49 25 0,000 0,09526222 0,11813482 ! vacuole organization GO:0007033 49 25 0,000 0,09526222 0,11807488 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,09526222 0,11801501 ! chromosome condensation GO:0030261 48 25 0,000 0,09526222 0,11795519 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,09526222 0,11789544 ! regulation of behavior GO:0050795 48 25 0,000 0,09526222 0,11783574 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,09526222 0,11777611 ! interaction with host GO:0051701 66 25 0,000 0,09526222 0,11771654 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,09526222 0,11765702 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,09526222 0,11759757 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,09526222 0,11753818 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,09526222 0,11747884 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,09526222 0,11741957 ! liver development GO:0001889 55 25 0,000 0,09526222 0,11736036 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,09887923 0,12175502 ! initiation of viral infection GO:0019059 60 26 0,000 0,09887923 0,12169368 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,09887923 0,12163241 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,09887923 0,12157119 ! molting cycle process GO:0022404 52 26 0,000 0,09887923 0,12151004 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 0,000 0,09887923 0,12144895 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,09887923 0,12138792 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,09887923 0,12132695 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,09887923 0,12126604 ! digestive system process GO:0022600 49 26 0,000 0,09887923 0,1212052 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,09887923 0,12114441 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,09887923 0,12108369 ! osteoblast differentiation GO:0001649 63 26 0,000 0,09887923 0,12102303 ! neural crest cell development GO:0014032 59 26 0,000 0,09887923 0,12096242 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,09887923 0,12090188 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,09887923 0,1208414 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,09887923 0,12078098 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,09887923 0,12072062 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,09887923 0,12066032 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,09887923 0,12060008 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,09887923 0,1205399 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,09887923 0,12047978 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,09887923 0,12041972 ! telomere organization GO:0032200 46 26 0,000 0,09887923 0,12035972 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,09887923 0,12029978 ! alditol metabolic process GO:0019400 44 26 0,000 0,09887923 0,1202399 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,09887923 0,12018008 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,09887923 0,12012032 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,10248189 0,12443501 ! embryonic pattern specification GO:0009880 49 27 0,000 0,10248189 0,1243732 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,10248189 0,12431144 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,10248189 0,12424975 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,10248189 0,12418812 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,10248189 0,12412655 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,10248189 0,12406504 ! iron ion transport GO:0006826 65 27 0,000 0,10248189 0,12400359 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,10248189 0,1239422 ! superoxide metabolic process GO:0006801 41 27 0,000 0,10248189 0,12388088 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,10248189 0,12381961 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,10248189 0,1237584 ! response to toxin GO:0009636 49 27 0,000 0,10248189 0,12369726 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,10248189 0,12363617 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,10248189 0,12357515 ! leukocyte proliferation GO:0070661 59 27 0,000 0,10248189 0,12351418 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,10607024 0,12777594 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,10607024 0,12771296 ! vesicle docking GO:0048278 55 28 0,000 0,10607024 0,12765005 ! circadian rhythm GO:0007623 56 28 0,000 0,10607024 0,1275872 ! dendrite development GO:0016358 67 28 0,000 0,10607024 0,12752441 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,10607024 0,12746168 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,10607024 0,12739902 ! sperm motility GO:0030317 37 28 0,000 0,10607024 0,12733641 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,10607024 0,12727387 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,10607024 0,12721139 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,10607024 0,12714897 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,10607024 0,12708661 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,10607024 0,12702431 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,10607024 0,12696208 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,10607024 0,1268999 ! glutathione metabolic process GO:0006749 42 28 0,000 0,10607024 0,12683779 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,10607024 0,12677573 ! lipid oxidation GO:0034440 48 28 0,000 0,10607024 0,12671374 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,10607024 0,12665181 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,10607024 0,12658994 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,10964435 0,13079157 ! translational initiation GO:0006413 66 29 0,000 0,10964435 0,13072774 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,10964435 0,13066397 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,10964435 0,13060027 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,10964435 0,13053662 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,10964435 0,13047304 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,10964435 0,13040952 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,10964435 0,13034606 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,10964435 0,13028266 ! synaptogenesis GO:0007416 46 29 0,000 0,10964435 0,13021932 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,10964435 0,13015605 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,10964435 0,13009283 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,10964435 0,13002968 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,10964435 0,12996659 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,11320427 0,13412125 ! phenol metabolic process GO:0018958 56 30 0,000 0,11320427 0,13405624 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,11320427 0,13399129 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11320427 0,1339264 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11320427 0,13386158 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11320427 0,13379682 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11320427 0,13373212 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11320427 0,13366748 ! acute-phase response GO:0006953 50 30 0,000 0,11320427 0,13360291 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11320427 0,1335384 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,11320427 0,13347395 ! myofibril assembly GO:0030239 50 30 0,000 0,11320427 0,13340956 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11320427 0,13334524 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11320427 0,13328098 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11320427 0,13321678 ! cell fate determination GO:0001709 64 30 0,000 0,11320427 0,13315264 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,11320427 0,13308856 ! phospholipid transport GO:0015914 65 30 0,000 0,11320427 0,13302454 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11320427 0,13296059 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11320427 0,1328967 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11320427 0,13283287 ! regulation of coagulation GO:0050818 52 30 0,000 0,11320427 0,1327691 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,11675005 0,13686199 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,11675005 0,13679634 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,11675005 0,13673077 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,11675005 0,13666525 ! regulation of innate immune response GO:0045088 57 31 0,000 0,11675005 0,1365998 ! ovulation cycle process GO:0022602 55 31 0,000 0,11675005 0,13653441 ! peptide transport GO:0015833 60 31 0,000 0,11675005 0,13646908 ! male gonad development GO:0008584 56 31 0,000 0,11675005 0,13640382 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,11675005 0,13633861 ! detection of light stimulus GO:0009583 44 31 0,000 0,11675005 0,13627347 ! natural killer cell activation GO:0030101 50 31 0,000 0,11675005 0,13620839 ! cofactor catabolic process GO:0051187 54 31 0,000 0,11675005 0,13614338 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,11675005 0,13607842 ! eye morphogenesis GO:0048592 65 31 0,000 0,11675005 0,13601353 ! response to heat GO:0009408 54 31 0,000 0,11675005 0,1359487 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,11675005 0,13588393 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,12028176 0,13992778 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,12028176 0,13986118 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,12028176 0,13979464 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,12028176 0,13972817 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,12028176 0,13966176 ! metanephros development GO:0001656 81 32 0,000 0,12028176 0,13959541 ! muscle cell development GO:0055001 52 32 0,000 0,12028176 0,13952912 ! mesoderm formation GO:0001707 73 32 0,000 0,12028176 0,1394629 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,12028176 0,13939674 ! ovulation cycle GO:0042698 57 32 0,000 0,12028176 0,13933065 ! hindbrain development GO:0030902 65 32 0,000 0,12028176 0,13926461 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,12028176 0,13919864 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,12028176 0,13913274 ! gene silencing GO:0016458 71 32 0,000 0,12028176 0,13906689 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,12379944 0,14306624 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,12379944 0,1429986 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,12379944 0,14293102 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,12379944 0,1428635 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,12379944 0,14279605 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,12379944 0,14272866 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,12379944 0,14266134 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,12379944 0,14259408 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,12379944 0,14252688 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,12379944 0,14245974 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,12379944 0,14239267 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,12730316 0,1463537 ! glial cell differentiation GO:0010001 67 34 0,000 0,12730316 0,14628486 ! post-embryonic development GO:0009791 76 34 0,000 0,12730316 0,14621609 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,12730316 0,14614738 ! cholesterol transport GO:0030301 62 34 0,000 0,12730316 0,14607873 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,12730316 0,14601015 ! spliceosome assembly GO:0000245 75 34 0,000 0,12730316 0,14594163 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,12730316 0,14587318 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,12730316 0,14580479 ! formation of primary germ layer GO:0001704 76 34 0,000 0,12730316 0,14573647 ! cell fate specification GO:0001708 56 34 0,000 0,12730316 0,14566821 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,12730316 0,14560001 ! adult locomotory behavior GO:0008344 62 34 0,000 0,12730316 0,14553188 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,12730316 0,14546381 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,13079296 0,14938158 ! negative regulation of secretion GO:0051048 68 35 0,000 0,13079296 0,14931178 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,13079296 0,14924204 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,13079296 0,14917237 ! membrane docking GO:0022406 69 35 0,000 0,13079296 0,14910276 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,13079296 0,14903321 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,13079296 0,14896373 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,13079296 0,14889432 ! ceramide metabolic process GO:0006672 72 35 0,000 0,13079296 0,14882497 ! telencephalon development GO:0021537 81 35 0,000 0,13079296 0,14875568 ! sterol transport GO:0015918 63 35 0,000 0,13079296 0,14868646 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,13079296 0,14861731 ! placenta development GO:0001890 53 35 0,000 0,13079296 0,14854821 ! vesicle localization GO:0051648 70 35 0,000 0,13079296 0,14847919 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,13426891 0,15235437 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,13426891 0,15228363 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,13426891 0,15221297 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,13426891 0,15214237 ! positive regulation of cell development GO:0010720 85 36 0,000 0,13426891 0,15207183 ! protein targeting to membrane GO:0006612 75 36 0,000 0,13426891 0,15200137 ! regulation of proteolysis GO:0030162 77 36 0,000 0,13426891 0,15193096 ! aerobic respiration GO:0009060 56 36 0,000 0,13426891 0,15186062 ! cytokine production GO:0001816 68 36 0,000 0,13426891 0,15179035 ! embryonic organ development GO:0048568 67 36 0,000 0,13426891 0,15172014 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,13426891 0,15165 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,13426891 0,15157992 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,13773105 0,15541661 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,13773105 0,15534486 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,13773105 0,15527317 ! sister chromatid segregation GO:0000819 65 37 0,000 0,13773105 0,15520155 ! odontogenesis GO:0042476 74 37 0,000 0,13773105 0,15513 ! actomyosin structure organization GO:0031032 68 37 0,000 0,13773105 0,15505851 ! tissue remodeling GO:0048771 78 37 0,000 0,13773105 0,15498709 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,13773105 0,15491573 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,13773105 0,15484444 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,14117945 0,1586483 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,14117945 0,15857536 ! meiosis I GO:0007127 74 38 0,000 0,14117945 0,15850248 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,14117945 0,15842967 ! organic anion transport GO:0015711 82 38 0,000 0,14117945 0,15835693 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,14117945 0,15828426 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,14117945 0,15821165 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,14117945 0,15813911 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,14117945 0,15806663 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,14117945 0,15799423 ! spermatid development GO:0007286 69 38 0,000 0,14117945 0,15792189 ! glycogen metabolic process GO:0005977 63 38 0,000 0,14117945 0,15784961 ! pigment metabolic process GO:0042440 87 38 0,000 0,14117945 0,1577774 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,14461415 0,16154201 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,14461415 0,16146818 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,14461415 0,16139441 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,14461415 0,16132072 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,14461415 0,16124709 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,14461415 0,16117353 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,14461415 0,16110003 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,14461415 0,16102661 ! glucan metabolic process GO:0044042 64 39 0,000 0,14461415 0,16095325 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,14803521 0,1646858 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,14803521 0,16461085 ! learning GO:0007612 82 40 0,000 0,14803521 0,16453595 ! lipid homeostasis GO:0055088 75 40 0,000 0,14803521 0,16446113 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,14803521 0,16438638 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,14803521 0,16431169 ! RNA export from nucleus GO:0006405 61 41 0,000 0,15144269 0,16801748 ! mRNA catabolic process GO:0006402 79 41 0,000 0,15144269 0,16794121 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,15144269 0,16786501 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,15144269 0,16778888 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,15144269 0,16771282 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,15144269 0,16763683 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,15144269 0,16756091 ! gliogenesis GO:0042063 91 41 0,000 0,15144269 0,16748506 ! feeding behavior GO:0007631 69 41 0,000 0,15144269 0,16740927 ! mesenchymal cell development GO:0014031 94 41 0,000 0,15144269 0,16733355 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,15144269 0,16725791 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,15144269 0,16718233 ! RNA modification GO:0009451 64 41 0,000 0,15144269 0,16710682 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,15483663 0,17077467 ! organic ether metabolic process GO:0018904 59 42 0,000 0,15483663 0,1706976 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,15483663 0,17062061 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,15483663 0,17054368 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,15483663 0,17046683 ! regulation of protein secretion GO:0050708 77 42 0,000 0,15483663 0,17039004 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,15483663 0,17031332 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,15821709 0,17395336 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,15821709 0,17387511 ! regulation of tube size GO:0035150 76 43 0,000 0,15821709 0,17379693 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,15821709 0,17371881 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,15821709 0,17364077 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,15821709 0,1735628 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,15821709 0,1734849 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,15821709 0,17340707 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,15821709 0,17332931 ! ion transmembrane transport GO:0034220 79 43 0,000 0,15821709 0,17325162 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,15821709 0,173174 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,16158413 0,17678013 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,16158413 0,176701 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,16158413 0,17662194 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,16158413 0,17654295 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,16158413 0,17646403 ! striated muscle contraction GO:0006941 85 44 0,000 0,16158413 0,17638518 ! phagocytosis GO:0006909 105 44 0,000 0,16158413 0,1763064 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,16158413 0,17622769 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,16493779 0,17980501 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,16493779 0,17972481 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,16493779 0,17964469 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,16493779 0,17956463 ! biopolymer methylation GO:0043414 91 45 0,000 0,16493779 0,17948465 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,16493779 0,17940473 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,16493779 0,17932489 ! polyol metabolic process GO:0019751 77 45 0,000 0,16493779 0,17924512 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,16827814 0,1827939 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,16827814 0,18271266 ! glycolysis GO:0006096 71 46 0,000 0,16827814 0,18263149 ! leukocyte migration GO:0050900 75 46 0,000 0,16827814 0,1825504 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,16827814 0,18246937 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,16827814 0,18238842 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,16827814 0,18230753 ! cell growth GO:0016049 90 46 0,000 0,16827814 0,18222672 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,17160521 0,18574725 ! positive regulation of defense response GO:0031349 88 48 0,000 0,17491907 0,18925035 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,17491907 0,18916657 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,17491907 0,18908287 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,17491907 0,18899924 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,17491907 0,18891569 ! male sex differentiation GO:0046661 93 48 0,000 0,17491907 0,18883221 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,17491907 0,1887488 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,17491907 0,18866547 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,17491907 0,18858221 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,17491907 0,18849903 ! methylation GO:0032259 97 48 0,000 0,17491907 0,18841591 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,17821977 0,19188669 ! JNK cascade GO:0007254 106 49 0,000 0,17821977 0,19180215 ! protein homooligomerization GO:0051260 84 49 0,000 0,17821977 0,1917177 ! regulation of ion transport GO:0043269 86 50 0,000 0,18150735 0,19516834 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,18150735 0,19508247 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,18150735 0,19499668 ! regulation of ossification GO:0030278 123 50 0,000 0,18150735 0,19491097 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,18150735 0,19482533 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,18150735 0,19473977 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,18150735 0,19465428 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,18150735 0,19456887 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,18150735 0,19448353 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,18478188 0,19790536 ! viral infectious cycle GO:0019058 104 51 0,000 0,18478188 0,19781863 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,18478188 0,19773198 ! peptide metabolic process GO:0006518 80 51 0,000 0,18478188 0,19764541 ! response to temperature stimulus GO:0009266 84 51 0,000 0,18478188 0,19755892 ! Notch signaling pathway GO:0007219 111 52 0,000 0,18804339 0,20095801 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,18804339 0,20087014 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,18804339 0,20078234 ! excretion GO:0007588 87 52 0,000 0,18804339 0,20069463 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,18804339 0,20060699 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,18804339 0,20051943 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,18804339 0,20043194 ! amino acid activation GO:0043038 98 52 0,000 0,18804339 0,20034453 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,19129195 0,20371675 ! positive regulation of growth GO:0045927 96 53 0,000 0,19129195 0,20362799 ! inner ear development GO:0048839 89 53 0,000 0,19129195 0,2035393 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,19129195 0,20345069 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,19129195 0,20336215 ! vesicle organization GO:0016050 127 53 0,000 0,19129195 0,2032737 ! regulation of translational initiation GO:0006446 87 54 0,000 0,1945276 0,20662214 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,1945276 0,20653235 ! neuromuscular process GO:0050905 107 54 0,000 0,1945276 0,20644263 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,1945276 0,20635299 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,1945276 0,20626342 ! membrane fusion GO:0006944 122 54 0,000 0,1945276 0,20617394 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,1945276 0,20608453 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,1945276 0,2059952 ! regulation of cell shape GO:0008360 142 54 0,000 0,1945276 0,20590595 ! RNA catabolic process GO:0006401 103 55 0,000 0,1977504 0,2092266 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1977504 0,20913603 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,1977504 0,20904553 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,1977504 0,20895511 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,1977504 0,20886478 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,20096039 0,21216346 ! glucose catabolic process GO:0006007 88 56 0,000 0,20096039 0,21207181 ! RNA elongation GO:0006354 90 56 0,000 0,20096039 0,21198024 ! chloride transport GO:0006821 102 57 0,000 0,20415763 0,21525986 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,20415763 0,21516699 ! heart morphogenesis GO:0003007 105 57 0,000 0,20415763 0,21507421 ! regulation of actin filament length GO:0030832 118 58 0,000 0,20734217 0,21833488 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,20734217 0,21824081 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,20734217 0,21814682 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,20734217 0,21805291 ! gastrulation GO:0007369 122 58 0,000 0,20734217 0,21795909 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,20734217 0,21786534 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,20734217 0,21777167 ! establishment of organelle localization GO:0051656 122 59 0,000 0,21051405 0,22100809 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,21367333 0,2242285 ! regulation of endocytosis GO:0030100 104 60 0,000 0,21367333 0,22413222 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,21367333 0,22403603 ! adult behavior GO:0030534 104 60 0,000 0,21367333 0,22393991 ! kidney development GO:0001822 133 60 0,000 0,21367333 0,22384389 ! positive regulation of secretion GO:0051047 110 61 0,000 0,21682005 0,22704303 ! regulation of cellular component size GO:0032535 125 61 0,000 0,21682005 0,22694575 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,21682005 0,22684856 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,21682005 0,22675145 ! regulation of heart contraction GO:0008016 123 61 0,000 0,21682005 0,22665442 ! camera-type eye development GO:0043010 126 61 0,000 0,21682005 0,22655748 ! proton transport GO:0015992 117 61 0,000 0,21682005 0,22646062 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,21682005 0,22636384 ! viral reproductive process GO:0022415 132 62 0,000 0,21995427 0,22953793 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,21995427 0,22943992 ! tRNA processing GO:0008033 102 62 0,000 0,21995427 0,22934199 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,22307604 0,23249777 ! regulation of mitosis GO:0007088 112 63 0,000 0,22307604 0,23239862 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,22307604 0,23229956 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,22307604 0,23220058 ! hydrogen transport GO:0006818 121 64 0,000 0,2261854 0,23533685 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,2261854 0,23523667 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,2292824 0,23835613 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,2292824 0,23825475 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,2292824 0,23815345 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,2292824 0,23805224 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,2292824 0,23795111 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,2323671 0,24105003 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,2323671 0,24094772 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,2323671 0,24084549 ! activation of MAPK activity GO:0000187 124 67 0,000 0,23543953 0,24392654 ! chromosome segregation GO:0007059 127 67 0,000 0,23543953 0,24382314 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,23543953 0,24371982 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,23543953 0,24361659 ! secondary metabolic process GO:0019748 125 67 0,000 0,23543953 0,24351345 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,23543953 0,2434104 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,23849976 0,24646993 ! hexose catabolic process GO:0019320 113 68 0,000 0,23849976 0,24636571 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,23849976 0,24626158 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,23849976 0,24615754 ! viral reproduction GO:0016032 142 68 0,000 0,23849976 0,24605359 ! adaptive immune response GO:0002250 126 68 0,000 0,23849976 0,24594973 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,24154782 0,2489879 ! urogenital system development GO:0001655 149 69 0,000 0,24154782 0,24888289 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,24154782 0,24877796 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,24154782 0,24867312 ! single fertilization GO:0007338 83 69 0,000 0,24154782 0,24856838 ! cell redox homeostasis GO:0045454 114 70 0,000 0,24458377 0,25158659 ! activation of immune response GO:0002253 120 70 0,000 0,24458377 0,2514807 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,24760765 0,25448274 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,24760765 0,25437573 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,25061951 0,25736169 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,25061951 0,25725355 ! humoral immune response GO:0006959 115 73 0,000 0,25361939 0,26022351 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,25361939 0,26011427 ! regulation of immune effector process GO:0002697 156 73 0,000 0,25361939 0,26000511 ! acute inflammatory response GO:0002526 118 74 0,000 0,25660736 0,26295796 ! amino acid transport GO:0006865 148 74 0,000 0,25660736 0,2628477 ! organelle localization GO:0051640 155 74 0,000 0,25660736 0,26273754 ! transition metal ion transport GO:0000041 143 75 0,000 0,25958344 0,26567338 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,25958344 0,26556212 ! eye development GO:0001654 155 75 0,000 0,25958344 0,26545096 ! rhythmic process GO:0048511 142 75 0,000 0,25958344 0,2653399 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,2625477 0,26825764 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,2625477 0,2681455 ! regulation of blood pressure GO:0008217 134 76 0,000 0,2625477 0,26803344 ! amine catabolic process GO:0009310 136 77 0,000 0,26550017 0,27093438 ! neurotransmitter transport GO:0006836 142 77 0,000 0,26550017 0,27082126 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,26550017 0,27070823 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,26550017 0,27059529 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,26550017 0,27048245 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,2684409 0,27336437 ! antigen processing and presentation GO:0019882 117 78 0,000 0,2684409 0,27325047 ! fertilization GO:0009566 99 78 0,000 0,2684409 0,27313666 ! blood coagulation GO:0007596 151 79 0,000 0,27136994 0,27600199 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,27136994 0,27588713 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,27136994 0,27577237 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,27136994 0,2756577 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,27428734 0,27850539 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,27428734 0,27838968 ! muscle cell differentiation GO:0042692 178 81 0,000 0,27719314 0,28122211 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,27719314 0,28110537 ! exocytosis GO:0006887 153 83 0,000 0,28297012 0,28684481 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,28297012 0,28672584 ! inorganic anion transport GO:0015698 156 83 0,000 0,28297012 0,28660696 ! digestion GO:0007586 130 84 0,000 0,28584139 0,28939516 ! hemostasis GO:0007599 165 85 0,000 0,28870125 0,29216949 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,28870125 0,29204851 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,28870125 0,29192763 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,29438689 0,29755365 ! alcohol catabolic process GO:0046164 142 87 0,000 0,29438689 0,29743059 ! nucleosome assembly GO:0006334 126 87 0,000 0,29438689 0,29730764 ! cellular respiration GO:0045333 143 88 0,000 0,29721277 0,30003751 ! sensory perception of smell GO:0007608 117 88 0,000 0,29721277 0,29991358 ! chromatin assembly GO:0031497 128 88 0,000 0,29721277 0,29978975 ! cellular defense response GO:0006968 123 89 0,000 0,3000274 0,3025039 ! regulation of neurological system process GO:0031644 175 89 0,000 0,3000274 0,3023791 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,30283085 0,30507866 ! defense response to bacterium GO:0042742 112 91 0,000 0,30562314 0,30776477 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,30840433 0,31043749 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,31117446 0,31309687 ! amine transport GO:0015837 181 93 0,000 0,31117446 0,31296797 ! vitamin metabolic process GO:0006766 153 93 0,000 0,31117446 0,31283918 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,31393357 0,31548322 ! female pregnancy GO:0007565 166 94 0,000 0,31393357 0,3153535 ! sterol metabolic process GO:0016125 166 94 0,000 0,31393357 0,31522388 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,31393357 0,31509438 ! regulation of defense response GO:0031347 171 95 0,000 0,31668171 0,31772214 ! nucleosome organization GO:0034728 143 95 0,000 0,31668171 0,31759171 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,31668171 0,31746139 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,31668171 0,31733118 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,31668171 0,31720107 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,32214523 0,32254131 ! forebrain development GO:0030900 210 98 0,000 0,3248607 0,32512687 ! positive regulation of immune response GO:0050778 175 100 0,000 0,33025929 0,33039453 ! hormone metabolic process GO:0042445 171 100 0,000 0,33025929 0,33025929