pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6348-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein sumoylation GO:0016925 15 10 6,000 2,073E-14 4,987E-11 ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,266E-07 1,523E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,153E-07 1,727E-04 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 4,907E-07 2,951E-04 GO:0050927|positive regulation of positive chemotaxis, ! L-serine biosynthetic process GO:0006564 6 5 2,000 1,815E-06 8,735E-04 ! positive regulation of protein complex assembly GO:0031334 32 17 3,000 2,307E-06 9,251E-04 ! negative regulation of axon extension GO:0030517 21 6 2,000 3,615E-06 1,243E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 4,634E-06 1,394E-03 ! inactivation of MAPK activity GO:0000188 39 21 3,000 5,699E-06 1,523E-03 ! positive regulation of locomotion GO:0040017 39 21 3,000 5,699E-06 1,371E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of protein export from nucleus GO:0046825 10 7 2,000 6,3E-06 1,378E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 6,3E-06 1,263E-03 ! regulation of chemotaxis GO:0050920 40 22 3,000 6,934E-06 1,283E-03 ! protein import into nucleus, translocation GO:0000060 46 24 3,000 9,983E-06 1,716E-03 ! regulation of behavior GO:0050795 43 24 3,000 9,983E-06 1,601E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,004E-05 1,509E-03 ! ER overload response GO:0006983 12 8 2,000 1,004E-05 1,421E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,004E-05 1,342E-03 ! mitochondrion organization GO:0007005 148 86 5,000 1,024E-05 1,297E-03 ! negative regulation of cell development GO:0010721 73 25 3,000 1,183E-05 1,423E-03 GO:0050768|negative regulation of neurogenesis, ! regulation of cell morphogenesis GO:0022604 215 89 5,000 1,248E-05 1,43E-03 ! response to UV GO:0009411 104 53 4,000 1,318E-05 1,441E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,392E-05 1,456E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,499E-05 1,503E-03 ! mitochondrion localization GO:0051646 15 9 2,000 1,499E-05 1,443E-03 ! regulation of protein localization GO:0032880 176 97 5,000 2,044E-05 1,892E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 2,133E-05 1,901E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 2,133E-05 1,833E-03 ! negative regulation of axonogenesis GO:0050771 32 10 2,000 2,133E-05 1,769E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,133E-05 1,711E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 3,000 2,865E-05 2,224E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 2,92E-05 2,196E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,92E-05 2,129E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,92E-05 2,067E-03 GO:0010829|negative regulation of glucose transport, ! regulation of axonogenesis GO:0050770 75 32 3,000 3,26E-05 2,241E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 3,26E-05 2,179E-03 ! negative regulation of cell projection organization GO:0031345 37 12 2,000 3,877E-05 2,521E-03 ! response to X-ray GO:0010165 25 13 2,000 5,019E-05 3,178E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 5,019E-05 3,097E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 5,019E-05 3,019E-03 ! negative regulation of DNA binding GO:0043392 68 37 3,000 5,856E-05 3,436E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 5,856E-05 3,355E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 6,361E-05 3,559E-03 ! response to gamma radiation GO:0010332 28 14 2,000 6,361E-05 3,479E-03 ! regulation of axon extension GO:0030516 37 14 2,000 6,361E-05 3,401E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 6,361E-05 3,327E-03 ! regulation of neuron projection development GO:0010975 91 38 3,000 6,516E-05 3,336E-03 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 3,000 6,516E-05 3,266E-03 ! regulation of transcription factor activity GO:0051090 126 74 4,000 6,714E-05 3,297E-03 GO:0090046|regulation of transcription regulator activity, ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7,918E-05 3,81E-03 ! negative regulation of binding GO:0051100 72 40 3,000 7,996E-05 3,772E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 1,065E-04 4,93E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,065E-04 4,837E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,174E-04 5,229E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,174E-04 5,134E-03 ! DNA integration GO:0015074 29 17 2,000 1,174E-04 5,042E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,174E-04 4,953E-03 ! pigmentation GO:0043473 100 46 3,000 1,39E-04 5,767E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,39E-04 5,669E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,402E-04 5,623E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 1,531E-04 6,039E-03 ! gland development GO:0048732 206 88 4,000 1,531E-04 5,942E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,643E-04 6,274E-03 ! cellular pigmentation GO:0033059 36 19 2,000 1,658E-04 6,234E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 1,781E-04 6,593E-03 ! regulation of cell projection organization GO:0031344 121 50 3,000 1,927E-04 7,026E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,943E-04 6,976E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,943E-04 6,874E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,943E-04 6,774E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 29 20 2,000 1,943E-04 6,677E-03 ! cartilage development GO:0051216 90 52 3,000 2,246E-04 7,61E-03 ! cell aging GO:0007569 44 21 2,000 2,257E-04 7,542E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,257E-04 7,439E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 2,602E-04 8,461E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,602E-04 8,349E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 2,602E-04 8,239E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,98E-04 9,312E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,206E-04 9,89E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,206E-04 9,765E-03 ! negative chemotaxis GO:0050919 14 5 1,000 3,206E-04 9,643E-03 ! anagen GO:0042640 6 5 1,000 3,206E-04 9,524E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,206E-04 9,408E-03 ! microvillus organization GO:0032528 7 5 1,000 3,206E-04 9,294E-03 GO:0030033|microvillus assembly, ! melanin biosynthetic process from tyrosine GO:0006583 6 5 1,000 3,206E-04 9,184E-03 ! response to food GO:0032094 6 5 1,000 3,206E-04 9,076E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,206E-04 8,97E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 3,206E-04 8,867E-03 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 3,206E-04 8,766E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,206E-04 8,668E-03 ! response to cadmium ion GO:0046686 7 5 1,000 3,206E-04 8,572E-03 ! decidualization GO:0046697 11 5 1,000 3,206E-04 8,477E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,206E-04 8,385E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,206E-04 8,295E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 3,206E-04 8,207E-03 GO:0022011|myelination in the peripheral nervous system, ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,392E-04 8,59E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 3,392E-04 8,501E-03 ! myelination GO:0042552 45 25 2,000 3,838E-04 9,52E-03 ! vasculogenesis GO:0001570 46 25 2,000 3,838E-04 9,423E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 3,838E-04 9,328E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 3,838E-04 9,235E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 3,838E-04 9,143E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,904E-04 9,208E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,904E-04 9,119E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 4,159E-04 9,622E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 4,159E-04 9,531E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 4,321E-04 9,807E-03 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 49 26 2,000 4,321E-04 9,715E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 4,427E-04 9,861E-03 ! male meiosis GO:0007140 7 6 1,000 4,791E-04 0,01057622 ! short-chain fatty acid metabolic process GO:0046459 8 6 1,000 4,791E-04 0,01048007 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 4,791E-04 0,01038566 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 4,791E-04 0,01029293 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,791E-04 0,01020184 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,791E-04 0,01011235 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 4,791E-04 0,01002442 ! astrocyte development GO:0014002 15 6 1,000 4,791E-04 9,938E-03 ! response to copper ion GO:0046688 10 6 1,000 4,791E-04 9,853E-03 ! hair follicle maturation GO:0048820 7 6 1,000 4,791E-04 9,77E-03 ! Schwann cell development GO:0014044 15 6 1,000 4,791E-04 9,687E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,791E-04 9,607E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,791E-04 9,527E-03 ! maternal placenta development GO:0001893 12 6 1,000 4,791E-04 9,449E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 5,398E-04 0,01055997 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 5,398E-04 0,01047481 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 5,949E-04 0,01145035 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 5,949E-04 0,01135948 ! negative regulation of kinase activity GO:0033673 131 68 3,000 6,293E-04 0,01192152 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 6,635E-04 0,01247098 ! ensheathment of neurons GO:0007272 57 30 2,000 6,635E-04 0,01237431 GO:0008366|axon ensheathment, ! regulation of helicase activity GO:0051095 15 7 1,000 6,683E-04 0,01236822 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,683E-04 0,0122738 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,683E-04 0,01218082 ! mRNA stabilization GO:0048255 18 7 1,000 6,683E-04 0,01208923 GO:0043489|RNA stabilization, ! melanosome organization GO:0032438 9 7 1,000 6,683E-04 0,01199901 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 6,683E-04 0,01191013 ! centrosome duplication GO:0051298 13 7 1,000 6,683E-04 0,01182256 ! B cell lineage commitment GO:0002326 21 7 1,000 6,683E-04 0,01173626 ! prostate gland development GO:0030850 13 7 1,000 6,683E-04 0,01165122 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,683E-04 0,0115674 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 6,683E-04 0,01148477 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,683E-04 0,01140332 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 6,683E-04 0,01132301 ! T cell lineage commitment GO:0002360 16 7 1,000 6,683E-04 0,01124383 ! response to tumor cell GO:0002347 13 7 1,000 6,683E-04 0,01116575 ! peptidyl-histidine modification GO:0018202 16 7 1,000 6,683E-04 0,01108874 ! axonal fasciculation GO:0007413 18 7 1,000 6,683E-04 0,01101279 ! melanin biosynthetic process GO:0042438 8 7 1,000 6,683E-04 0,01093788 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 7,315E-04 0,01189142 ! negative regulation of transferase activity GO:0051348 140 72 3,000 7,81E-04 0,0126113 ! response to ionizing radiation GO:0010212 65 32 2,000 8,038E-04 0,01289251 ! peripheral nervous system development GO:0007422 64 32 2,000 8,038E-04 0,01280713 ! positive regulation of catabolic process GO:0009896 64 32 2,000 8,038E-04 0,01272287 ! axon guidance GO:0007411 139 73 3,000 8,226E-04 0,01293624 ! DNA damage checkpoint GO:0000077 71 33 2,000 8,805E-04 0,0137557 ! leukocyte chemotaxis GO:0030595 50 33 2,000 8,805E-04 0,01366696 GO:0060326|cell chemotaxis, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 8,877E-04 0,01369086 ! oligopeptide transport GO:0006857 15 8 1,000 8,877E-04 0,01360366 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,877E-04 0,01351756 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,877E-04 0,01343254 ! pigment granule organization GO:0048753 16 8 1,000 8,877E-04 0,01334859 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,877E-04 0,01326568 ! astrocyte differentiation GO:0048708 18 8 1,000 8,877E-04 0,01318379 ! melanin metabolic process GO:0006582 15 8 1,000 8,877E-04 0,01310291 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 8,877E-04 0,01302301 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,877E-04 0,01294409 ! Schwann cell differentiation GO:0014037 19 8 1,000 8,877E-04 0,01286611 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 8,877E-04 0,01278907 ! blastocyst growth GO:0001832 19 8 1,000 8,877E-04 0,01271294 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 8,877E-04 0,01263772 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,877E-04 0,01256338 ! placenta development GO:0001890 53 34 2,000 9,616E-04 0,01353029 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,047E-03 0,01465129 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,047E-03 0,0145666 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 1,106E-03 0,0152914 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,137E-03 0,01563251 ! cellular copper ion homeostasis GO:0006878 12 9 1,000 1,137E-03 0,01554369 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,137E-03 0,01545587 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,137E-03 0,01536904 ! motor axon guidance GO:0008045 16 9 1,000 1,137E-03 0,01528318 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,137E-03 0,01519827 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,137E-03 0,0151143 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,138E-03 0,01504198 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,138E-03 0,01495978 ! protein import into nucleus GO:0006606 158 80 3,000 1,159E-03 0,01515433 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 1,214E-03 0,01578553 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 3,000 1,214E-03 0,01570067 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,214E-03 0,01561671 ! glycogen metabolic process GO:0005977 61 37 2,000 1,233E-03 0,01578066 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,27E-03 0,01617226 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,333E-03 0,01688221 ! glucan metabolic process GO:0044042 62 38 2,000 1,333E-03 0,01679383 GO:0006073|cellular glucan metabolic process, ! negative regulation of transport GO:0051051 153 84 3,000 1,389E-03 0,01740754 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,416E-03 0,01765172 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,416E-03 0,01756073 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,416E-03 0,01747068 ! lung alveolus development GO:0048286 26 10 1,000 1,416E-03 0,01738154 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,416E-03 0,01729331 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,416E-03 0,01720597 GO:0005978|glycogen biosynthetic process, ! multicellular organism growth GO:0035264 18 10 1,000 1,416E-03 0,01711951 ! copper ion homeostasis GO:0055070 13 10 1,000 1,416E-03 0,01703391 ! regulation of bone resorption GO:0045124 25 10 1,000 1,416E-03 0,01694917 ! apical protein localization GO:0045176 15 10 1,000 1,416E-03 0,01686526 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,416E-03 0,01678218 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,416E-03 0,01669991 ! oocyte development GO:0048599 17 10 1,000 1,416E-03 0,01661845 ! blastocyst formation GO:0001825 17 10 1,000 1,416E-03 0,01653778 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,416E-03 0,01645789 ! localization within membrane GO:0051668 20 10 1,000 1,416E-03 0,01637876 ! mammary gland development GO:0030879 86 39 2,000 1,438E-03 0,01655708 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,438E-03 0,01647824 ! protein localization in nucleus GO:0034504 176 87 3,000 1,581E-03 0,01803296 ! telencephalon cell migration GO:0022029 20 11 1,000 1,724E-03 0,01956713 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,724E-03 0,01947526 ! blood vessel remodeling GO:0001974 29 11 1,000 1,724E-03 0,01938426 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,724E-03 0,0192941 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,724E-03 0,01920478 ! melanocyte differentiation GO:0030318 21 11 1,000 1,724E-03 0,01911627 GO:0050931|pigment cell differentiation, ! regulation of intracellular pH GO:0051453 19 11 1,000 1,724E-03 0,01902858 ! nitric oxide metabolic process GO:0046209 15 11 1,000 1,724E-03 0,0189417 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,724E-03 0,0188556 ! oocyte differentiation GO:0009994 18 11 1,000 1,724E-03 0,01877028 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,784E-03 0,0193365 ! ossification GO:0001503 188 90 3,000 1,792E-03 0,01932936 ! bone development GO:0060348 189 91 3,000 1,866E-03 0,02003927 ! energy reserve metabolic process GO:0006112 74 43 2,000 1,91E-03 0,02042414 ! double-strand break repair GO:0006302 81 44 2,000 2,041E-03 0,02173072 ! developmental growth GO:0048589 82 44 2,000 2,041E-03 0,02163499 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,061E-03 0,02175096 ! cartilage condensation GO:0001502 20 12 1,000 2,061E-03 0,02165598 ! drug transport GO:0015893 16 12 1,000 2,061E-03 0,02156183 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,061E-03 0,02146848 ! forebrain cell migration GO:0021885 21 12 1,000 2,061E-03 0,02137595 ! asymmetric protein localization GO:0008105 20 12 1,000 2,061E-03 0,02128421 ! histone acetylation GO:0016573 26 12 1,000 2,061E-03 0,02119325 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,061E-03 0,02110306 ! T cell homeostasis GO:0043029 25 12 1,000 2,061E-03 0,02101364 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,061E-03 0,02092498 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,061E-03 0,02083706 ! response to cold GO:0009409 17 12 1,000 2,061E-03 0,02074987 ! leukocyte migration GO:0050900 68 45 2,000 2,178E-03 0,02183345 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,32E-03 0,02316297 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,32E-03 0,02306726 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,356E-03 0,02332285 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,427E-03 0,02393008 GO:0000725|recombinational repair, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,427E-03 0,0238324 ! regulation of cellular pH GO:0030641 22 13 1,000 2,427E-03 0,02373552 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,427E-03 0,02363943 ! embryonic placenta development GO:0001892 23 13 1,000 2,427E-03 0,02354411 ! positive regulation of defense response GO:0031349 76 47 2,000 2,468E-03 0,02384767 ! activation of caspase activity GO:0006919 84 48 2,000 2,622E-03 0,02523035 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,622E-03 0,02512984 ! cell cycle arrest GO:0007050 213 100 3,000 2,631E-03 0,02511832 ! regulation of action potential GO:0001508 95 49 2,000 2,781E-03 0,02644667 ! response to temperature stimulus GO:0009266 76 49 2,000 2,781E-03 0,02634254 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 2,781E-03 0,02623924 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,821E-03 0,0265101 ! regulation of S phase GO:0033261 23 14 1,000 2,821E-03 0,02640695 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,821E-03 0,0263046 ! bone mineralization GO:0030282 17 14 1,000 2,821E-03 0,02620303 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,821E-03 0,02610225 ! regulation of RNA stability GO:0043487 32 14 1,000 2,821E-03 0,02600224 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 3,117E-03 0,02862677 ! regulation of cell shape GO:0008360 125 51 2,000 3,117E-03 0,02851792 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,242E-03 0,02955063 ! pituitary gland development GO:0021983 29 15 1,000 3,242E-03 0,02943911 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,242E-03 0,02932844 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,242E-03 0,0292186 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,242E-03 0,02910957 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 3,242E-03 0,02900136 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,242E-03 0,02889394 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,294E-03 0,02924846 ! positive regulation of growth GO:0045927 90 52 2,000 3,294E-03 0,02914092 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,692E-03 0,03253659 ! response to osmotic stress GO:0006970 25 16 1,000 3,692E-03 0,03241784 ! DNA replication initiation GO:0006270 27 16 1,000 3,692E-03 0,03229996 ! neuron recognition GO:0008038 35 16 1,000 3,692E-03 0,03218293 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,692E-03 0,03206675 ! biomineral formation GO:0031214 20 16 1,000 3,692E-03 0,0319514 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,692E-03 0,03183688 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,692E-03 0,03172317 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,862E-03 0,0330698 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 3,862E-03 0,03295253 ! regulation of protein catabolic process GO:0042176 116 55 2,000 3,862E-03 0,03283609 ! aging GO:0007568 103 55 2,000 3,862E-03 0,03272047 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 3,862E-03 0,03260567 ! nucleotide-excision repair GO:0006289 83 56 2,000 4,064E-03 0,03418829 ! regulation of DNA replication GO:0006275 101 56 2,000 4,064E-03 0,03406916 ! glial cell development GO:0021782 27 17 1,000 4,168E-03 0,03482352 ! limbic system development GO:0021761 36 17 1,000 4,168E-03 0,03470302 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,168E-03 0,03458336 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,168E-03 0,03446452 ! neural crest cell migration GO:0001755 37 17 1,000 4,168E-03 0,03434649 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,168E-03 0,03422926 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 4,272E-03 0,03495996 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,272E-03 0,03484145 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,272E-03 0,03472374 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,272E-03 0,03460683 ! regulation of tissue remodeling GO:0034103 140 58 2,000 4,486E-03 0,0362211 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,672E-03 0,03759413 ! patterning of blood vessels GO:0001569 39 18 1,000 4,672E-03 0,03746882 ! centrosome cycle GO:0007098 25 18 1,000 4,672E-03 0,03734434 ! positive regulation of proteolysis GO:0045862 31 18 1,000 4,672E-03 0,03722068 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 4,672E-03 0,03709784 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 4,672E-03 0,03697581 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,707E-03 0,03713101 ! regulation of heart contraction GO:0008016 110 60 2,000 4,934E-03 0,03879599 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,934E-03 0,03866962 ! lipid phosphorylation GO:0046834 35 19 1,000 5,202E-03 0,04063681 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,202E-03 0,0405053 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,202E-03 0,04037463 ! cerebral cortex development GO:0021987 36 19 1,000 5,202E-03 0,04024481 ! pigmentation during development GO:0048066 41 19 1,000 5,202E-03 0,04011582 ! neuromuscular junction development GO:0007528 34 19 1,000 5,202E-03 0,03998766 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,202E-03 0,03986031 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,202E-03 0,03973377 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 5,655E-03 0,04305672 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,758E-03 0,04370626 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,758E-03 0,04356881 ! response to alkaloid GO:0043279 38 20 1,000 5,758E-03 0,04343224 ! cellular response to starvation GO:0009267 33 20 1,000 5,758E-03 0,04329651 ! diencephalon development GO:0021536 34 20 1,000 5,758E-03 0,04316163 ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,758E-03 0,04302759 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,758E-03 0,04289438 ! positive regulation of cell motion GO:0051272 146 64 2,000 5,909E-03 0,04387634 ! germ cell development GO:0007281 118 65 2,000 6,169E-03 0,04566795 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,341E-03 0,04679795 ! oogenesis GO:0048477 36 21 1,000 6,341E-03 0,04665483 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,341E-03 0,04651259 ! developmental maturation GO:0021700 116 66 2,000 6,436E-03 0,04706528 ! lung development GO:0030324 144 67 2,000 6,71E-03 0,04891885 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,949E-03 0,05051096 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,949E-03 0,05035882 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 6,949E-03 0,05020759 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 6,99E-03 0,05035453 ! cell cycle checkpoint GO:0000075 137 69 2,000 7,278E-03 0,05226912 ! negative regulation of cell size GO:0045792 134 69 2,000 7,278E-03 0,05211355 ! respiratory tube development GO:0030323 150 70 2,000 7,572E-03 0,05406094 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,582E-03 0,05397378 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,582E-03 0,05381456 ! reproductive structure development GO:0048608 113 71 2,000 7,874E-03 0,05571663 ! regulation of caspase activity GO:0043281 122 72 2,000 8,182E-03 0,05772901 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 8,182E-03 0,05756021 ! respiratory system development GO:0060541 153 72 2,000 8,182E-03 0,0573924 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,241E-03 0,05763784 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,241E-03 0,05747077 ! pallium development GO:0021543 49 24 1,000 8,241E-03 0,05730467 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,241E-03 0,05713953 ! protein tetramerization GO:0051262 52 24 1,000 8,241E-03 0,05697533 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 8,82E-03 0,06080306 ! organelle localization GO:0051640 136 74 2,000 8,82E-03 0,06062933 ! protein amino acid alkylation GO:0008213 53 25 1,000 8,924E-03 0,06117162 GO:0006479|protein amino acid methylation, ! response to starvation GO:0042594 42 25 1,000 8,924E-03 0,06099784 ! neural crest cell development GO:0014032 54 25 1,000 8,924E-03 0,06082504 GO:0014033|neural crest cell differentiation, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 8,924E-03 0,06065322 ! somitogenesis GO:0001756 43 25 1,000 8,924E-03 0,06048236 ! cellular response to nutrient levels GO:0031669 41 25 1,000 8,924E-03 0,06031247 ! regulation of catabolic process GO:0009894 161 76 2,000 9,486E-03 0,06393053 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 9,632E-03 0,06473151 ! molting cycle process GO:0022404 50 26 1,000 9,632E-03 0,0645512 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! microtubule organizing center organization GO:0031023 39 26 1,000 9,632E-03 0,06437189 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 9,632E-03 0,06419358 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 9,632E-03 0,06401625 ! protein oligomerization GO:0051259 139 78 2,000 0,01018079 0,06747928 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01036352 0,06850172 ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 0,01036352 0,06831404 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01036352 0,06812739 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01036352 0,06794176 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01036352 0,06775713 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01036352 0,06757351 ! response to toxin GO:0009636 47 27 1,000 0,01036352 0,06739088 ! base-excision repair GO:0006284 41 27 1,000 0,01036352 0,06720923 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01036352 0,06702856 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01036352 0,06684886 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01053901 0,06779909 ! dendrite development GO:0016358 59 28 1,000 0,01111919 0,07134069 ! response to hypoxia GO:0001666 171 81 2,000 0,01127719 0,072162 ! response to drug GO:0042493 143 82 2,000 0,01165719 0,07439577 ! regulation of pH GO:0006885 43 29 1,000 0,01189841 0,07573434 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01189841 0,07553451 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01189841 0,07533574 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01189841 0,07513801 ! tissue homeostasis GO:0001894 48 29 1,000 0,01189841 0,07494131 GO:0048871|multicellular organismal homeostasis, ! response to oxygen levels GO:0070482 176 83 2,000 0,01204451 0,07566339 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01270091 0,07957913 ! response to heat GO:0009408 50 30 1,000 0,01270091 0,07937243 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01325051 0,08259254 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01352639 0,08409428 ! peptide transport GO:0015833 55 31 1,000 0,01352639 0,08387755 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01352639 0,08366192 ! regulation of protein transport GO:0051223 154 87 2,000 0,01366726 0,08431648 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01409142 0,08671087 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,01437456 0,08822754 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01437456 0,08800304 ! sex differentiation GO:0007548 145 90 2,000 0,01496201 0,091367 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01524515 0,09286033 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01524515 0,09262583 ! regulation of defense response GO:0031347 149 92 2,000 0,01586241 0,09613338 ! glial cell differentiation GO:0010001 63 34 1,000 0,01613787 0,09755707 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,01613787 0,09731256 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01632381 0,09818774 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01632381 0,09794288 ! female gonad development GO:0008585 58 35 1,000 0,01705244 0,10206015 ! telencephalon development GO:0021537 68 35 1,000 0,01705244 0,1018069 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01705244 0,1015549 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01705244 0,10130415 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,01726909 0,10233852 ! regulation of proteolysis GO:0030162 72 36 1,000 0,0179886 0,10634045 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,0179886 0,10607981 ! protein ubiquitination GO:0016567 217 97 2,000 0,01824439 0,10732522 ! interphase GO:0051325 213 98 2,000 0,01874332 0,10999131 ! tissue remodeling GO:0048771 76 37 1,000 0,01894606 0,11091048 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01894606 0,11064128 ! pigment metabolic process GO:0042440 80 37 1,000 0,01894606 0,11037339 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01924978 0,1118719 GO:0060538|skeletal muscle organ development, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01992455 0,11551437 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01992455 0,11523669 ! learning GO:0007612 77 39 1,000 0,02092381 0,12072586 ! ear morphogenesis GO:0042471 60 39 1,000 0,02092381 0,12043704 ! segmentation GO:0035282 67 39 1,000 0,02092381 0,1201496 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,02092381 0,11986353 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02194357 0,12540671 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,02194357 0,12510953 ! gliogenesis GO:0042063 88 41 1,000 0,02298356 0,1307292 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02298356 0,13042088 ! T cell differentiation GO:0030217 81 41 1,000 0,02298356 0,130114 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02298356 0,12980857 ! female gamete generation GO:0007292 61 41 1,000 0,02298356 0,12950457 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02404353 0,13516061 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02404353 0,13484555 ! glucose transport GO:0015758 65 43 1,000 0,02512322 0,14057317 ! hexose transport GO:0008645 67 44 1,000 0,02622236 0,14638283 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02622236 0,14604398 ! biopolymer methylation GO:0043414 84 44 1,000 0,02622236 0,1457067 ! B cell differentiation GO:0030183 107 44 1,000 0,02622236 0,14537097 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02734071 0,1512224 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02734071 0,15087556 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02734071 0,1505303 ! cell growth GO:0016049 84 45 1,000 0,02734071 0,15018663 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02823285 0,15473402 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02823285 0,15438236 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02823285 0,15403228 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02823285 0,15368379 ! neuron fate determination GO:0048664 7 5 0,000 0,02823285 0,15333688 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02823285 0,15299152 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02823285 0,15264772 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02823285 0,15230546 ! polyol transport GO:0015791 12 5 0,000 0,02823285 0,15196474 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02823285 0,15162553 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02823285 0,15128783 ! response to superoxide GO:0000303 10 5 0,000 0,02823285 0,15095164 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02823285 0,15061693 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02823285 0,15028371 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02823285 0,14995196 ! female meiosis GO:0007143 7 5 0,000 0,02823285 0,14962167 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02823285 0,14929283 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02823285 0,14896543 ! cobalt ion transport GO:0006824 11 5 0,000 0,02823285 0,14863947 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02823285 0,14831493 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02823285 0,1479918 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02823285 0,14767008 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02823285 0,14734975 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02823285 0,14703082 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02823285 0,14671325 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02823285 0,14639706 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02823285 0,14608223 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02823285 0,14576875 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02823285 0,14545661 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02823285 0,1451458 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02823285 0,14483633 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02823285 0,14452816 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02823285 0,14422131 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02823285 0,14391576 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02823285 0,14361149 ! behavioral response to pain GO:0048266 9 5 0,000 0,02823285 0,14330852 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02823285 0,14300681 ! Notch receptor processing GO:0007220 8 5 0,000 0,02823285 0,14270638 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02823285 0,1424072 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02823285 0,14210928 ! micturition GO:0060073 9 5 0,000 0,02823285 0,1418126 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02823285 0,14151716 ! copulation GO:0007620 9 5 0,000 0,02823285 0,14122295 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02823285 0,14092995 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02823285 0,14063817 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02823285 0,1403476 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02823285 0,14005822 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02823285 0,13977003 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02823285 0,13948303 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02823285 0,13919721 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02823285 0,13891255 ! grooming behavior GO:0007625 6 5 0,000 0,02823285 0,13862905 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02823285 0,13834671 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02823285 0,13806552 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02823285 0,13778547 ! response to protozoan GO:0001562 10 5 0,000 0,02823285 0,13750655 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02823285 0,13722876 ! lymph vessel development GO:0001945 10 5 0,000 0,02823285 0,13695209 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02823285 0,13667653 ! endochondral ossification GO:0001958 16 5 0,000 0,02823285 0,13640208 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02823285 0,13612873 ! parathyroid gland development GO:0060017 13 5 0,000 0,02823285 0,13585647 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02823285 0,1355853 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02823285 0,13531521 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02823285 0,1350462 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02823285 0,13477825 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02823285 0,13451136 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02823285 0,13424553 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02823285 0,13398074 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02823285 0,133717 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02823285 0,1334543 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02823285 0,13319262 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02823285 0,13293197 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02823285 0,13267234 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02823285 0,13241372 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02823285 0,1321561 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02823285 0,13189949 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02823285 0,13164387 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02823285 0,13138924 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02823285 0,13113559 ! histidine catabolic process GO:0006548 6 5 0,000 0,02823285 0,13088292 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02823285 0,13063122 ! valine metabolic process GO:0006573 10 5 0,000 0,02823285 0,13038049 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02823285 0,13013072 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02823285 0,12988191 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02823285 0,12963404 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02823285 0,12938712 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02823285 0,12914113 ! polyol catabolic process GO:0046174 7 5 0,000 0,02823285 0,12889608 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02823285 0,12865196 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02823285 0,12840877 ! muscle cell migration GO:0014812 8 5 0,000 0,02823285 0,12816648 ! mitochondrial fission GO:0000266 8 5 0,000 0,02823285 0,12792512 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02823285 0,12768466 ! mRNA transcription GO:0009299 9 5 0,000 0,02823285 0,1274451 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02823285 0,12720644 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02823285 0,12696867 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02823285 0,12673178 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02823285 0,12649579 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02823285 0,12626066 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02823285 0,12602641 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02823285 0,12579303 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02823285 0,12556051 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02823285 0,12532885 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02823285 0,12509804 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02823285 0,12486808 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02823285 0,12463897 ! forebrain neuron development GO:0021884 13 5 0,000 0,02823285 0,12441069 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02823285 0,12418325 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02823285 0,12395664 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02823285 0,12373085 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02823285 0,12350588 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02823285 0,12328174 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02823285 0,1230584 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02823285 0,12283587 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02823285 0,12261415 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02823285 0,12239322 ! basic amino acid transport GO:0015802 11 5 0,000 0,02823285 0,12217309 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02823285 0,12195375 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02823285 0,12173519 ! depyrimidination GO:0045008 10 5 0,000 0,02823285 0,12151742 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02823285 0,12130042 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02823285 0,1210842 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02823285 0,12086875 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02823285 0,12065406 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02823285 0,12044014 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02823285 0,12022697 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02823285 0,12001455 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02823285 0,11980289 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02823285 0,11959197 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02823285 0,11938179 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02823285 0,11917235 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02823285 0,11896364 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02823285 0,11875566 ! response to arsenic GO:0046685 10 5 0,000 0,02823285 0,11854841 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02823285 0,11834188 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02823285 0,11813606 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02823285 0,11793097 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02823285 0,11772658 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02823285 0,1175229 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02823285 0,11731993 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02823285 0,11711765 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02823285 0,11691607 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02823285 0,11671518 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02823285 0,11651499 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02823285 0,11631547 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02823285 0,11611664 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02823285 0,11591849 ! neural tube patterning GO:0021532 7 5 0,000 0,02823285 0,11572102 ! embryonic cleavage GO:0040016 6 5 0,000 0,02823285 0,11552421 ! peroxisome fission GO:0016559 5 5 0,000 0,02823285 0,11532808 ! histone demethylation GO:0016577 10 5 0,000 0,02823285 0,1151326 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02823285 0,11493779 ! mitotic recombination GO:0006312 9 5 0,000 0,02823285 0,11474364 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02823285 0,11455015 ! metaphase plate congression GO:0051310 7 5 0,000 0,02823285 0,1143573 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02823285 0,1141651 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02823285 0,11397355 ! enteric nervous system development GO:0048484 8 5 0,000 0,02823285 0,11378264 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02823285 0,11359237 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02823285 0,11340273 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02823285 0,11321373 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02823285 0,11302535 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02823285 0,1128376 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02823285 0,11265048 ! plasminogen activation GO:0031639 5 5 0,000 0,02823285 0,11246397 ! B cell homeostasis GO:0001782 13 5 0,000 0,02823285 0,11227808 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02823285 0,1120928 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02823285 0,11190813 ! metaphase GO:0051323 8 5 0,000 0,02823285 0,11172407 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02823285 0,11154062 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02823285 0,11135777 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02823285 0,11117551 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02823285 0,11099385 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02823285 0,11081278 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02823285 0,11063231 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02823285 0,11045242 ! response to redox state GO:0051775 5 5 0,000 0,02823285 0,11027311 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02823285 0,11009439 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02823285 0,10991624 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02823285 0,10973867 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02823285 0,10956167 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02823285 0,10938524 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02823285 0,10920938 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02823285 0,10903409 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02823285 0,10885935 ! striatum development GO:0021756 9 5 0,000 0,02823285 0,10868518 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02823285 0,10851156 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02823285 0,1083385 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02823285 0,10816598 ! glial cell migration GO:0008347 11 5 0,000 0,02823285 0,10799402 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02823285 0,1078226 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02823285 0,10765172 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02823285 0,10748139 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02823285 0,10731159 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02823285 0,10714233 ! neuroprotection GO:0043526 6 5 0,000 0,02823285 0,1069736 ! neural plate development GO:0001840 8 5 0,000 0,02823285 0,1068054 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02823285 0,10663773 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02823285 0,10647059 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02823285 0,10630397 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02823285 0,10613787 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02823285 0,10597229 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02823285 0,10580722 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02823285 0,10564267 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02823285 0,10547863 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02823285 0,1053151 ! spindle assembly GO:0051225 6 5 0,000 0,02823285 0,10515207 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02823285 0,10498955 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02823285 0,10482753 ! drug metabolic process GO:0017144 6 5 0,000 0,02823285 0,104666 ! stem cell division GO:0017145 11 5 0,000 0,02823285 0,10450498 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02823285 0,10434445 ! organ regeneration GO:0031100 7 5 0,000 0,02823285 0,10418441 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02823285 0,10402486 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02823285 0,10386581 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02823285 0,10370723 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02847801 0,1044483 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02847801 0,10428932 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02847801 0,10413082 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02963401 0,10819335 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02963401 0,10802942 ! methylation GO:0032259 90 47 1,000 0,02963401 0,10786599 ! protein homooligomerization GO:0051260 76 47 1,000 0,02963401 0,10770305 ! mitochondrial transport GO:0006839 82 48 1,000 0,03080846 0,11180264 ! cellular component disassembly GO:0022411 86 48 1,000 0,03080846 0,11163426 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03080846 0,11146639 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,03080846 0,11129902 ! endocrine system development GO:0035270 104 49 1,000 0,03200112 0,11543431 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03200112 0,11526151 ! regulation of ossification GO:0030278 117 50 1,000 0,03321174 0,11944312 ! histone modification GO:0016570 91 50 1,000 0,03321174 0,11926484 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03321174 0,1190871 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03378359 0,12095733 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03378359 0,1207776 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03378359 0,1205984 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03378359 0,12041974 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03378359 0,1202416 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03378359 0,12006399 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03378359 0,11988691 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03378359 0,11971034 ! sleep GO:0030431 13 6 0,000 0,03378359 0,1195343 ! response to oxygen radical GO:0000305 11 6 0,000 0,03378359 0,11935877 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03378359 0,11918376 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03378359 0,11900926 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03378359 0,11883527 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03378359 0,11866178 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03378359 0,11848881 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03378359 0,11831634 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03378359 0,11814436 ! forebrain regionalization GO:0021871 8 6 0,000 0,03378359 0,11797289 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03378359 0,11780192 ! response to zinc ion GO:0010043 9 6 0,000 0,03378359 0,11763144 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03378359 0,11746145 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03378359 0,11729195 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03378359 0,11712294 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03378359 0,11695442 ! malate metabolic process GO:0006108 11 6 0,000 0,03378359 0,11678638 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03378359 0,11661883 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03378359 0,11645175 ! protein refolding GO:0042026 15 6 0,000 0,03378359 0,11628515 ! opsonization GO:0008228 8 6 0,000 0,03378359 0,11611903 ! mating behavior GO:0007617 7 6 0,000 0,03378359 0,11595338 ! neuron remodeling GO:0016322 15 6 0,000 0,03378359 0,11578821 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03378359 0,1156235 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03378359 0,11545926 ! equilibrioception GO:0050957 14 6 0,000 0,03378359 0,11529549 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03378359 0,11513218 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03378359 0,11496934 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03378359 0,11480695 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03378359 0,11464502 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03378359 0,11448355 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03378359 0,11432254 ! toxin metabolic process GO:0009404 11 6 0,000 0,03378359 0,11416197 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03378359 0,11400185 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03378359 0,11384219 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03378359 0,11368297 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03378359 0,11352419 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03378359 0,11336586 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03378359 0,11320797 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03378359 0,11305052 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03378359 0,1128935 ! thymic T cell selection GO:0045061 12 6 0,000 0,03378359 0,11273692 ! protein lipoylation GO:0009249 10 6 0,000 0,03378359 0,11258078 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03378359 0,11242507 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03378359 0,11226978 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03378359 0,11211493 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03378359 0,1119605 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03378359 0,1118065 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03378359 0,11165292 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03378359 0,11149976 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03378359 0,11134702 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03378359 0,1111947 ! hyperosmotic response GO:0006972 9 6 0,000 0,03378359 0,11104279 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03378359 0,1108913 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03378359 0,11074022 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03378359 0,11058955 ! urea metabolic process GO:0019627 7 6 0,000 0,03378359 0,1104393 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03378359 0,11028945 ! neutrophil activation GO:0042119 8 6 0,000 0,03378359 0,11014 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03378359 0,10999096 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03378359 0,10984233 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03378359 0,10969409 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03378359 0,10954626 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03378359 0,10939882 ! neuron apoptosis GO:0051402 9 6 0,000 0,03378359 0,10925178 ! nucleoside salvage GO:0043174 9 6 0,000 0,03378359 0,10910513 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03378359 0,10895888 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03378359 0,10881302 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03378359 0,10866754 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03378359 0,10852246 ! carnitine transport GO:0015879 10 6 0,000 0,03378359 0,10837776 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03378359 0,10823345 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03378359 0,10808952 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03378359 0,10794598 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03378359 0,10780282 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03378359 0,10766003 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03378359 0,10751762 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03378359 0,10737559 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03378359 0,10723393 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03378359 0,10709265 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03378359 0,10695174 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03378359 0,1068112 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03378359 0,10667103 ! neural nucleus development GO:0048857 14 6 0,000 0,03378359 0,10653122 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03378359 0,10639178 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03378359 0,10625271 ! interaction with symbiont GO:0051702 13 6 0,000 0,03378359 0,106114 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03378359 0,10597565 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03378359 0,10583766 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03378359 0,10570003 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03378359 0,10556276 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03378359 0,10542584 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03378359 0,10528928 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03378359 0,10515307 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03378359 0,10501721 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03378359 0,10488171 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03378359 0,10474655 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03378359 0,10461174 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03378359 0,10447728 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03378359 0,10434316 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03378359 0,10420939 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03378359 0,10407596 ! subpallium development GO:0021544 10 6 0,000 0,03378359 0,10394287 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03378359 0,10381012 ! histone ubiquitination GO:0016574 8 6 0,000 0,03378359 0,10367771 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03378359 0,10354563 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03378359 0,1034139 ! G2 phase GO:0051319 16 6 0,000 0,03378359 0,10328249 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03378359 0,10315142 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03378359 0,10302069 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03378359 0,10289028 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03378359 0,10276021 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03378359 0,10263046 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03378359 0,10250104 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03378359 0,10237194 ! receptor internalization GO:0031623 10 6 0,000 0,03378359 0,10224317 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03378359 0,10211473 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03378359 0,1019866 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03378359 0,1018588 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03378359 0,10173132 ! protein deubiquitination GO:0016579 14 6 0,000 0,03378359 0,10160415 ! protein destabilization GO:0031648 9 6 0,000 0,03378359 0,10147731 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03378359 0,10135078 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03378359 0,10122456 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03378359 0,10109866 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03378359 0,10097307 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03378359 0,10084779 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03378359 0,10072283 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03378359 0,10059817 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03378359 0,10047382 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03378359 0,10034978 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03378359 0,10022605 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03378359 0,10010261 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03378359 0,09997949 ! catecholamine transport GO:0051937 9 6 0,000 0,03378359 0,09985666 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03378359 0,09973414 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03378359 0,09961191 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03378359 0,09948999 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03378359 0,09936836 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03378359 0,09924704 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03378359 0,099126 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03378359 0,09900526 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03378359 0,09888482 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03378359 0,09876467 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03378359 0,09864481 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03378359 0,09852524 ! positive regulation of binding GO:0051099 78 51 1,000 0,03444008 0,10031821 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03444008 0,10019691 ! vesicle organization GO:0016050 107 51 1,000 0,03444008 0,1000759 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,03444008 0,09995518 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03568591 0,10344615 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03568591 0,10332166 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03568591 0,10319748 ! synapse organization GO:0050808 85 52 1,000 0,03568591 0,10307359 ! cell maturation GO:0048469 100 53 1,000 0,03694898 0,10659383 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03694898 0,10646617 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03822907 0,11002289 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,03822907 0,10989144 ! tRNA transcription GO:0009304 14 7 0,000 0,03930281 0,11284316 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03930281 0,11270866 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03930281 0,11257448 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03930281 0,11244062 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03930281 0,11230708 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03930281 0,11217386 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03930281 0,11204095 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03930281 0,11190836 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03930281 0,11177608 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03930281 0,11164411 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03930281 0,11151246 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03930281 0,11138111 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03930281 0,11125008 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03930281 0,11111935 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03930281 0,11098893 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03930281 0,11085881 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03930281 0,110729 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03930281 0,11059949 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03930281 0,11047029 ! glycolipid transport GO:0046836 10 7 0,000 0,03930281 0,11034138 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03930281 0,11021278 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03930281 0,11008448 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03930281 0,10995647 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03930281 0,10982876 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03930281 0,10970135 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03930281 0,10957424 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03930281 0,10944741 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03930281 0,10932088 ! pericardium development GO:0060039 14 7 0,000 0,03930281 0,10919465 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03930281 0,1090687 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03930281 0,10894305 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03930281 0,10881768 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03930281 0,1086926 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03930281 0,10856781 ! lipoprotein transport GO:0042953 14 7 0,000 0,03930281 0,10844331 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03930281 0,10831909 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03930281 0,10819515 ! rhythmic behavior GO:0007622 15 7 0,000 0,03930281 0,1080715 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03930281 0,10794813 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03930281 0,10782505 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03930281 0,10770224 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03930281 0,10757971 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03930281 0,10745746 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03930281 0,10733549 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03930281 0,10721379 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03930281 0,10709237 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03930281 0,10697123 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03930281 0,10685036 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03930281 0,10672976 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03930281 0,10660943 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03930281 0,10648937 ! spinal cord patterning GO:0021511 13 7 0,000 0,03930281 0,10636959 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03930281 0,10625007 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03930281 0,10613082 ! adrenal gland development GO:0030325 17 7 0,000 0,03930281 0,10601184 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03930281 0,10589313 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03930281 0,10577468 ! ovulation GO:0030728 9 7 0,000 0,03930281 0,1056565 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03930281 0,10553858 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03930281 0,10542092 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03930281 0,10530352 ! microtubule nucleation GO:0007020 20 7 0,000 0,03930281 0,10518639 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03930281 0,10506952 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03930281 0,1049529 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03930281 0,10483655 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03930281 0,10472045 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03930281 0,10460461 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03930281 0,10448902 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03930281 0,10437369 ! galactose metabolic process GO:0006012 13 7 0,000 0,03930281 0,10425862 ! vesicle fusion GO:0006906 17 7 0,000 0,03930281 0,10414379 ! response to dietary excess GO:0002021 8 7 0,000 0,03930281 0,10402922 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03930281 0,10391491 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03930281 0,10380084 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03930281 0,10368702 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 0,000 0,03930281 0,10357346 ! purine salvage GO:0043101 10 7 0,000 0,03930281 0,10346014 ! nucleoside transport GO:0015858 8 7 0,000 0,03930281 0,10334707 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03930281 0,10323424 ! parturition GO:0007567 14 7 0,000 0,03930281 0,10312166 ! rRNA modification GO:0000154 14 7 0,000 0,03930281 0,10300933 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03930281 0,10289724 ! spindle checkpoint GO:0031577 15 7 0,000 0,03930281 0,1027854 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03930281 0,10267379 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03930281 0,10256243 ! macrophage differentiation GO:0030225 11 7 0,000 0,03930281 0,10245132 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03930281 0,10234044 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03930281 0,1022298 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03930281 0,1021194 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03930281 0,10200924 ! fibrinolysis GO:0042730 10 7 0,000 0,03930281 0,10189932 ! eating behavior GO:0042755 7 7 0,000 0,03930281 0,10178963 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03930281 0,10168018 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03930281 0,10157096 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03930281 0,10146198 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03930281 0,10135323 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03930281 0,10124472 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03930281 0,10113643 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03930281 0,10102838 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03930281 0,10092056 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03930281 0,10081297 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03930281 0,10070561 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03930281 0,10059847 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03930281 0,10049157 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03930281 0,10038489 ! regulation of meiosis GO:0040020 12 7 0,000 0,03930281 0,10027844 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03930281 0,10017221 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03930281 0,10006621 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03930281 0,09996043 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03930281 0,09985487 ! transcription termination GO:0006353 13 7 0,000 0,03930281 0,09974954 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03930281 0,09964443 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03930281 0,09953954 ! anaphase GO:0051322 17 7 0,000 0,03930281 0,09943487 GO:0000090|mitotic anaphase, ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03930281 0,09933043 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03930281 0,0992262 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03930281 0,09912219 ! diuresis GO:0030146 12 7 0,000 0,03930281 0,09901839 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03930281 0,09891482 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03930281 0,09881146 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03930281 0,09870831 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03930281 0,09860539 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03930281 0,09850267 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03930281 0,09840017 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03930281 0,09829788 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03930281 0,09819581 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03930281 0,09809395 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03930281 0,0979923 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03930281 0,09789085 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03930281 0,09778962 ! lymph node development GO:0048535 10 7 0,000 0,03930281 0,0976886 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03930281 0,09758779 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03930281 0,09748718 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03930281 0,09738678 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03930281 0,09728659 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03930281 0,0971866 ! adult feeding behavior GO:0008343 9 7 0,000 0,03930281 0,09708682 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03930281 0,09698725 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03930281 0,09688787 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03930281 0,09678871 ! muscle adaptation GO:0043500 14 7 0,000 0,03930281 0,09668974 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03930281 0,09659098 ! retina homeostasis GO:0001895 12 7 0,000 0,03930281 0,09649241 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03930281 0,09639405 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03930281 0,09629589 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03930281 0,09619793 ! protein prenylation GO:0018342 18 7 0,000 0,03930281 0,09610017 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03930281 0,0960026 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03930281 0,09590524 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03930281 0,09580807 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03952593 0,09625443 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03952593 0,09615711 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04083933 0,09925196 ! muscle fiber development GO:0048747 112 57 1,000 0,04216906 0,10238018 ! lipid modification GO:0030258 97 57 1,000 0,04216906 0,10227697 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04216906 0,10217397 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04351487 0,10532876 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04479069 0,10830793 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04479069 0,10819919 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04479069 0,10809066 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04479069 0,10798236 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04479069 0,10787427 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04479069 0,10776639 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04479069 0,10765873 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04479069 0,10755129 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04479069 0,10744406 ! meiotic prophase I GO:0007128 13 8 0,000 0,04479069 0,10733704 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04479069 0,10723024 ! UTP metabolic process GO:0046051 8 8 0,000 0,04479069 0,10712365 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04479069 0,10701727 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04479069 0,1069111 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04479069 0,10680515 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04479069 0,1066994 ! succinate metabolic process GO:0006105 14 8 0,000 0,04479069 0,10659386 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04479069 0,10648853 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04479069 0,10638341 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04479069 0,10627849 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04479069 0,10617379 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04479069 0,10606928 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04479069 0,10596499 ! reflex GO:0060004 16 8 0,000 0,04479069 0,1058609 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04479069 0,10575701 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04479069 0,10565333 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04479069 0,10554985 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04479069 0,10544657 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04479069 0,10534349 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04479069 0,10524062 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04479069 0,10513794 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04479069 0,10503547 ! histidine metabolic process GO:0006547 16 8 0,000 0,04479069 0,1049332 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04479069 0,10483112 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04479069 0,10472924 ! glycine catabolic process GO:0006546 13 8 0,000 0,04479069 0,10462757 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04479069 0,10452608 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04479069 0,1044248 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04479069 0,10432371 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04479069 0,10422282 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04479069 0,10412212 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04479069 0,10402161 ! macrophage activation GO:0042116 12 8 0,000 0,04479069 0,1039213 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04479069 0,10382119 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04479069 0,10372126 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04479069 0,10362153 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04479069 0,10352199 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04479069 0,10342264 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04479069 0,10332348 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04479069 0,10322451 ! osteoblast development GO:0002076 16 8 0,000 0,04479069 0,10312573 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04479069 0,10302714 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04479069 0,10292874 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04479069 0,10283053 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04479069 0,1027325 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04479069 0,10263466 ! response to UV-B GO:0010224 16 8 0,000 0,04479069 0,102537 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04479069 0,10243954 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04479069 0,10234225 ! intermediate filament organization GO:0045109 12 8 0,000 0,04479069 0,10224515 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04479069 0,10214824 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04479069 0,10205151 ! cellular extravasation GO:0045123 12 8 0,000 0,04479069 0,10195496 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04479069 0,10185859 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04479069 0,10176241 ! response to antibiotic GO:0046677 11 8 0,000 0,04479069 0,10166641 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04479069 0,10157059 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04479069 0,10147495 ! DNA topological change GO:0006265 12 8 0,000 0,04479069 0,10137948 ! response to tropane GO:0014073 15 8 0,000 0,04479069 0,1012842 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04479069 0,1011891 ! melanosome transport GO:0032402 13 8 0,000 0,04479069 0,10109418 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04479069 0,10099943 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04479069 0,10090486 ! mast cell activation GO:0045576 14 8 0,000 0,04479069 0,10081047 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04479069 0,10071625 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04479069 0,10062221 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04479069 0,10052835 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04479069 0,10043466 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04479069 0,10034115 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04479069 0,10024781 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04479069 0,10015464 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04479069 0,10006165 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04479069 0,09996882 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04479069 0,09987617 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04479069 0,0997837 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04479069 0,09969139 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04479069 0,09959925 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04479069 0,09950729 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04479069 0,09941549 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04479069 0,09932386 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04479069 0,09923241 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04479069 0,09914112 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04479069 0,09904999 ! hormone catabolic process GO:0042447 17 8 0,000 0,04479069 0,09895904 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04479069 0,09886825 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04479069 0,09877763 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04479069 0,09868717 ! ATP catabolic process GO:0006200 11 8 0,000 0,04479069 0,09859688 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04479069 0,09850676 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04479069 0,0984168 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04479069 0,098327 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04479069 0,09823737 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04479069 0,0981479 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04479069 0,09805859 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04479069 0,09796945 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04479069 0,09788047 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04479069 0,09779164 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04479069 0,09770298 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04479069 0,09761449 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04479069 0,09752615 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04479069 0,09743797 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04479069 0,09734995 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04479069 0,09726209 ! DNA catabolic process GO:0006308 86 59 1,000 0,04487655 0,09736068 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04487655 0,09727296 ! ear development GO:0043583 103 62 1,000 0,04905458 0,1062334 ! gonad development GO:0008406 98 62 1,000 0,04905458 0,10613787 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05024739 0,10862105 ! axon extension GO:0048675 15 9 0,000 0,05024739 0,10852355 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05024739 0,10842622 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05024739 0,10832906 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05024739 0,10823208 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05024739 0,10813527 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05024739 0,10803863 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05024739 0,10794217 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05024739 0,10784588 ! phosphate transport GO:0006817 19 9 0,000 0,05024739 0,10774976 ! reproductive behavior GO:0019098 19 9 0,000 0,05024739 0,10765381 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05024739 0,10755803 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05024739 0,10746243 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05024739 0,10736699 ! GTP metabolic process GO:0046039 9 9 0,000 0,05024739 0,10727172 ! RNA methylation GO:0001510 15 9 0,000 0,05024739 0,10717662 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05024739 0,10708169 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05024739 0,10698693 ! artery development GO:0060840 24 9 0,000 0,05024739 0,10689233 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05024739 0,10679791 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05024739 0,10670365 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05024739 0,10660955 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05024739 0,10651562 ! chemosensory behavior GO:0007635 20 9 0,000 0,05024739 0,10642186 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05024739 0,10632826 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05024739 0,10623482 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05024739 0,10614155 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05024739 0,10604845 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05024739 0,1059555 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05024739 0,10586272 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05024739 0,10577011 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05024739 0,10567765 ! protein targeting to ER GO:0045047 22 9 0,000 0,05024739 0,10558535 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05024739 0,10549322 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05024739 0,10540125 ! T cell selection GO:0045058 23 9 0,000 0,05024739 0,10530943 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05024739 0,10521778 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05024739 0,10512629 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05024739 0,10503495 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05024739 0,10494378 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05024739 0,10485276 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05024739 0,1047619 ! mannose metabolic process GO:0006013 13 9 0,000 0,05024739 0,10467119 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05024739 0,10458065 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05024739 0,10449026 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05024739 0,10440003 ! receptor clustering GO:0043113 18 9 0,000 0,05024739 0,10430995 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05024739 0,10422003 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05024739 0,10413026 ! ruffle organization GO:0031529 15 9 0,000 0,05024739 0,10404065 ! retinol metabolic process GO:0042572 18 9 0,000 0,05024739 0,10395119 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05024739 0,10386188 ! behavioral fear response GO:0001662 22 9 0,000 0,05024739 0,10377273 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05024739 0,10368373 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05024739 0,10359488 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05024739 0,10350619 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05024739 0,10341765 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05024739 0,10332926 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05024739 0,10324102 ! segment specification GO:0007379 13 9 0,000 0,05024739 0,10315293 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05024739 0,10306499 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05024739 0,1029772 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05024739 0,10288956 ! response to amine stimulus GO:0014075 13 9 0,000 0,05024739 0,10280207 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05024739 0,10271472 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05024739 0,10262753 ! erythrocyte development GO:0048821 15 9 0,000 0,05024739 0,10254048 ! gas homeostasis GO:0033483 16 9 0,000 0,05024739 0,10245358 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05024739 0,10236683 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05024739 0,10228023 ! renal water homeostasis GO:0003091 14 9 0,000 0,05024739 0,10219377 ! postreplication repair GO:0006301 22 9 0,000 0,05024739 0,10210746 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05024739 0,10202129 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05024739 0,10193527 ! icosanoid secretion GO:0032309 15 9 0,000 0,05024739 0,10184939 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05024739 0,10176366 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05024739 0,10167807 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05024739 0,10159263 ! regulation of cell division GO:0051302 15 9 0,000 0,05024739 0,10150733 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05024739 0,10142217 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05024739 0,10133716 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05024739 0,10125229 ! sterol catabolic process GO:0016127 11 9 0,000 0,05024739 0,10116756 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05024739 0,10108297 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05024739 0,10099852 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05024739 0,10091422 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05024739 0,10083005 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05024739 0,10074603 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05024739 0,10066214 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05024739 0,10057839 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05024739 0,10049479 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05024739 0,10041132 ! purine base metabolic process GO:0006144 21 9 0,000 0,05024739 0,10032799 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05024739 0,1002448 ! pigment granule transport GO:0051904 17 9 0,000 0,05024739 0,10016175 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05024739 0,10007883 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05024739 0,09999605 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05024739 0,09991341 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05024739 0,09983091 ! detection of external stimulus GO:0009581 91 63 1,000 0,05047751 0,10020536 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05191522 0,10297446 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05336749 0,10576786 ! secondary metabolic process GO:0019748 116 66 1,000 0,0548341 0,10858507 ! cell projection assembly GO:0030031 120 66 1,000 0,0548341 0,10849577 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05567311 0,11006533 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,05567311 0,10997496 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05567311 0,10988474 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05567311 0,10979467 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05567311 0,10970475 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05567311 0,10961498 ! synapsis GO:0007129 13 10 0,000 0,05567311 0,10952535 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05567311 0,10943587 ! N-glycan processing GO:0006491 20 10 0,000 0,05567311 0,10934653 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05567311 0,10925734 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05567311 0,1091683 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05567311 0,1090794 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05567311 0,10899064 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05567311 0,10890203 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05567311 0,10881357 ! androgen metabolic process GO:0008209 17 10 0,000 0,05567311 0,10872525 ! phospholipid efflux GO:0033700 16 10 0,000 0,05567311 0,10863707 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05567311 0,10854903 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05567311 0,10846114 ! pathogenesis GO:0009405 13 10 0,000 0,05567311 0,10837338 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05567311 0,10828577 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05567311 0,10819831 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05567311 0,10811098 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05567311 0,10802379 ! endoderm development GO:0007492 16 10 0,000 0,05567311 0,10793675 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05567311 0,10784984 ! arginine catabolic process GO:0006527 13 10 0,000 0,05567311 0,10776307 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05567311 0,10767645 ! proline metabolic process GO:0006560 13 10 0,000 0,05567311 0,10758996 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05567311 0,10750361 ! V(D)J recombination GO:0033151 28 10 0,000 0,05567311 0,1074174 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05567311 0,10733133 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05567311 0,1072454 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05567311 0,1071596 ! B cell proliferation GO:0042100 18 10 0,000 0,05567311 0,10707394 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05567311 0,10698842 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05567311 0,10690303 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05567311 0,10681778 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05567311 0,10673267 ! epithelial cell development GO:0002064 20 10 0,000 0,05567311 0,10664769 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05567311 0,10656285 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05567311 0,10647814 ! macroautophagy GO:0016236 17 10 0,000 0,05567311 0,10639357 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05567311 0,10630913 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05567311 0,10622482 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05567311 0,10614065 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05567311 0,10605661 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05567311 0,10597271 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05567311 0,10588893 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05567311 0,10580529 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05567311 0,10572179 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05567311 0,10563841 ! response to dsRNA GO:0043331 20 10 0,000 0,05567311 0,10555516 ! DNA ligation GO:0006266 19 10 0,000 0,05567311 0,10547205 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05567311 0,10538907 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05567311 0,10530621 ! melanosome localization GO:0032400 16 10 0,000 0,05567311 0,10522349 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05567311 0,1051409 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05567311 0,10505843 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05567311 0,1049761 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05567311 0,10489389 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05567311 0,10481182 ! mRNA cleavage GO:0006379 17 10 0,000 0,05567311 0,10472987 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05567311 0,10464805 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05567311 0,10456636 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05567311 0,10448479 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05567311 0,10440335 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05567311 0,10432204 ! salivary gland development GO:0007431 27 10 0,000 0,05567311 0,10424086 ! prophase GO:0051324 15 10 0,000 0,05567311 0,1041598 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05567311 0,10407887 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05567311 0,10399806 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05567311 0,10391738 ! midbrain development GO:0030901 13 10 0,000 0,05567311 0,10383682 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05567311 0,10375639 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05567311 0,10367609 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05567311 0,1035959 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05567311 0,10351584 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05567311 0,10343591 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05567311 0,1033561 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05567311 0,10327641 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05567311 0,10319684 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05567311 0,1031174 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05567311 0,10303808 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05567311 0,10295888 ! activation of innate immune response GO:0002218 12 10 0,000 0,05567311 0,1028798 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05567311 0,10280085 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05567311 0,10272201 ! response to nicotine GO:0035094 20 10 0,000 0,05567311 0,1026433 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05567311 0,1025647 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05567311 0,10248623 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,05631486 0,10358834 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,05631486 0,10350921 ! adaptive immune response GO:0002250 119 67 1,000 0,05631486 0,10343019 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,05780955 0,10609441 ! urogenital system development GO:0001655 137 69 1,000 0,05931796 0,10877973 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06106801 0,11190375 ! respiratory burst GO:0045730 17 11 0,000 0,06106801 0,11181859 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06106801 0,11173356 ! neuron fate specification GO:0048665 17 11 0,000 0,06106801 0,11164865 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06106801 0,11156388 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06106801 0,11147923 ! thyroid gland development GO:0030878 26 11 0,000 0,06106801 0,11139472 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06106801 0,11131033 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06106801 0,11122606 ! response to pain GO:0048265 24 11 0,000 0,06106801 0,11114193 ! T cell proliferation GO:0042098 26 11 0,000 0,06106801 0,11105792 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06106801 0,11097404 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,06106801 0,11089029 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06106801 0,11080666 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06106801 0,11072316 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06106801 0,11063978 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06106801 0,11055653 ! syncytium formation GO:0006949 18 11 0,000 0,06106801 0,11047341 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06106801 0,11039041 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06106801 0,11030753 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06106801 0,11022478 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,06106801 0,11014215 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06106801 0,11005965 ! UV protection GO:0009650 19 11 0,000 0,06106801 0,10997727 ! adult heart development GO:0007512 14 11 0,000 0,06106801 0,10989501 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06106801 0,10981288 ! temperature homeostasis GO:0001659 17 11 0,000 0,06106801 0,10973087 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06106801 0,10964898 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06106801 0,10956721 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06106801 0,10948557 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06106801 0,10940404 ! regulation of organ growth GO:0046620 13 11 0,000 0,06106801 0,10932264 ! pigment granule localization GO:0051875 20 11 0,000 0,06106801 0,10924136 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06106801 0,1091602 ! vasoconstriction GO:0042310 18 11 0,000 0,06106801 0,10907916 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06106801 0,10899824 ! embryonic axis specification GO:0000578 18 11 0,000 0,06106801 0,10891744 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06106801 0,10883676 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06106801 0,1087562 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06106801 0,10867576 ! DNA methylation GO:0006306 19 11 0,000 0,06106801 0,10859544 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06106801 0,10851524 ! zymogen activation GO:0031638 15 11 0,000 0,06106801 0,10843515 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06106801 0,10835518 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06106801 0,10827533 ! nucleosome positioning GO:0016584 15 11 0,000 0,06106801 0,1081956 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06106801 0,10811599 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06106801 0,10803649 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06106801 0,10795711 ! acid secretion GO:0046717 18 11 0,000 0,06106801 0,10787785 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06106801 0,1077987 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06106801 0,10771967 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06106801 0,10764075 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06106801 0,10756195 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06106801 0,10748327 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06106801 0,1074047 ! cholesterol efflux GO:0033344 19 11 0,000 0,06106801 0,10732624 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06106801 0,1072479 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06106801 0,10716968 ! germ cell migration GO:0008354 25 11 0,000 0,06106801 0,10709157 ! embryonic gut development GO:0048566 15 11 0,000 0,06106801 0,10701357 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06106801 0,10693568 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06106801 0,10685791 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06106801 0,10678025 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06106801 0,10670271 ! defense response to fungus GO:0050832 13 11 0,000 0,06106801 0,10662528 ! developmental induction GO:0031128 19 11 0,000 0,06106801 0,10654795 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06106801 0,10647075 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06106801 0,10639365 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06106801 0,10631666 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06106801 0,10623979 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06106801 0,10616303 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06106801 0,10608637 ! nucleus localization GO:0051647 19 11 0,000 0,06106801 0,10600983 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06106801 0,1059334 ! B cell activation GO:0042113 160 71 1,000 0,06237515 0,10812293 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06392353 0,11072716 ! carbohydrate transport GO:0008643 110 72 1,000 0,06392353 0,1106475 ! learning or memory GO:0007611 147 73 1,000 0,06548484 0,11326852 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06643227 0,11482473 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06643227 0,1147423 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06643227 0,11465999 ! virus-host interaction GO:0019048 29 12 0,000 0,06643227 0,1145778 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,06643227 0,11449572 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06643227 0,11441377 ! mating GO:0007618 17 12 0,000 0,06643227 0,11433192 ! protein complex disassembly GO:0043241 27 12 0,000 0,06643227 0,1142502 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06643227 0,11416859 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06643227 0,1140871 ! hippocampus development GO:0021766 26 12 0,000 0,06643227 0,11400573 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06643227 0,11392447 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06643227 0,11384333 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06643227 0,1137623 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06643227 0,11368139 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06643227 0,11360059 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06643227 0,11351991 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06643227 0,11343934 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06643227 0,11335889 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06643227 0,11327855 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06643227 0,11319832 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06643227 0,11311821 ! focal adhesion formation GO:0048041 35 12 0,000 0,06643227 0,11303821 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06643227 0,11295833 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06643227 0,11287855 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06643227 0,11279889 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06643227 0,11271934 ! entry into host cell GO:0030260 32 12 0,000 0,06643227 0,11263991 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06643227 0,11256058 ! monoamine transport GO:0015844 18 12 0,000 0,06643227 0,11248137 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06643227 0,11240227 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06643227 0,11232328 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06643227 0,1122444 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06643227 0,11216564 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06643227 0,11208698 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06643227 0,11200843 ! protein homotetramerization GO:0051289 21 12 0,000 0,06643227 0,11192999 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06643227 0,11185167 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06643227 0,11177345 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06643227 0,11169534 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06643227 0,11161734 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06643227 0,11153945 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06643227 0,11146167 ! cranial nerve development GO:0021545 20 12 0,000 0,06643227 0,11138399 ! fucose catabolic process GO:0019317 22 12 0,000 0,06643227 0,11130643 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06643227 0,11122897 ! histone methylation GO:0016571 26 12 0,000 0,06643227 0,11115162 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06643227 0,11107438 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06643227 0,11099724 ! gland morphogenesis GO:0022612 29 12 0,000 0,06643227 0,11092022 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06643227 0,11084329 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06643227 0,11076648 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06643227 0,11068977 ! spleen development GO:0048536 22 12 0,000 0,06643227 0,11061317 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06643227 0,11053667 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06643227 0,11046028 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06643227 0,110384 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06643227 0,11030782 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06643227 0,11023174 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06643227 0,11015578 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06643227 0,11007991 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06643227 0,11000415 ! meiosis GO:0007126 121 74 1,000 0,06705887 0,11096536 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,06864543 0,11351265 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,06864543 0,11343469 ! meiotic cell cycle GO:0051321 122 75 1,000 0,06864543 0,11335683 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,06864543 0,11327909 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,07024434 0,11583816 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07176605 0,11826652 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07176605 0,11818557 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07176605 0,11810473 ! peroxisomal transport GO:0043574 24 13 0,000 0,07176605 0,11802401 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07176605 0,11794339 ! lipid localization GO:0010876 28 13 0,000 0,07176605 0,11786288 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07176605 0,11778248 ! organelle fusion GO:0048284 32 13 0,000 0,07176605 0,1177022 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07176605 0,11762202 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07176605 0,11754195 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07176605 0,11746199 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07176605 0,11738214 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07176605 0,11730239 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07176605 0,11722276 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07176605 0,11714323 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07176605 0,11706381 ! methionine metabolic process GO:0006555 27 13 0,000 0,07176605 0,1169845 ! plasma membrane organization GO:0007009 24 13 0,000 0,07176605 0,1169053 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07176605 0,1168262 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07176605 0,11674721 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07176605 0,11666832 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07176605 0,11658955 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07176605 0,11651088 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07176605 0,11643231 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07176605 0,11635386 ! exocrine system development GO:0035272 32 13 0,000 0,07176605 0,1162755 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07176605 0,11619726 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07176605 0,11611911 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07176605 0,11604108 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07176605 0,11596314 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07176605 0,11588532 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07176605 0,11580759 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07176605 0,11572997 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07176605 0,11565246 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07176605 0,11557505 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07176605 0,11549774 ! ribosome assembly GO:0042255 17 13 0,000 0,07176605 0,11542054 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07176605 0,11534343 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07176605 0,11526644 ! chromatin silencing GO:0006342 26 13 0,000 0,07176605 0,11518954 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07176605 0,11511275 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07176605 0,11503606 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07176605 0,11495947 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07176605 0,11488298 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07176605 0,1148066 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07176605 0,11473031 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07176605 0,11465413 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07176605 0,11457805 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07176605 0,11450207 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07176605 0,11442619 ! insulin secretion GO:0030073 23 13 0,000 0,07176605 0,11435041 ! actin filament polymerization GO:0030041 24 13 0,000 0,07176605 0,11427473 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07176605 0,11419915 ! acrosome reaction GO:0007340 18 13 0,000 0,07176605 0,11412368 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,07347841 0,11676952 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,0751132 0,11928868 ! response to metal ion GO:0010038 140 80 1,000 0,07675957 0,12182291 ! rRNA transcription GO:0009303 25 14 0,000 0,07706954 0,12223422 ! lactation GO:0007595 26 14 0,000 0,07706954 0,1221537 ! reproductive cellular process GO:0048610 20 14 0,000 0,07706954 0,12207328 ! tRNA modification GO:0006400 20 14 0,000 0,07706954 0,12199297 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07706954 0,12191277 ! water transport GO:0006833 21 14 0,000 0,07706954 0,12183266 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07706954 0,12175267 ! non-recombinational repair GO:0000726 25 14 0,000 0,07706954 0,12167278 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07706954 0,12159299 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07706954 0,12151331 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07706954 0,12143374 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07706954 0,12135426 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07706954 0,1212749 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07706954 0,12119563 ! palate development GO:0060021 31 14 0,000 0,07706954 0,12111647 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07706954 0,12103741 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07706954 0,12095846 ! arginine metabolic process GO:0006525 17 14 0,000 0,07706954 0,12087961 ! regulation of heart rate GO:0002027 24 14 0,000 0,07706954 0,12080086 ! organic alcohol transport GO:0015850 29 14 0,000 0,07706954 0,12072221 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07706954 0,12064367 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07706954 0,12056522 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07706954 0,12048688 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07706954 0,12040865 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07706954 0,12033051 ! L-amino acid transport GO:0015807 30 14 0,000 0,07706954 0,12025247 ! stem cell development GO:0048864 43 14 0,000 0,07706954 0,12017454 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07706954 0,12009671 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07706954 0,12001897 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07706954 0,11994134 ! cerebellum development GO:0021549 21 14 0,000 0,07706954 0,11986381 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07706954 0,11978638 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07706954 0,11970905 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07706954 0,11963182 ! cofactor transport GO:0051181 26 14 0,000 0,07706954 0,11955468 ! NADP metabolic process GO:0006739 24 14 0,000 0,07706954 0,11947765 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07706954 0,11940072 ! intestinal absorption GO:0050892 25 14 0,000 0,07706954 0,11932388 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07706954 0,11924715 ! oxygen transport GO:0015671 21 14 0,000 0,07706954 0,11917051 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07706954 0,11909397 ! male genitalia development GO:0030539 24 14 0,000 0,07706954 0,11901753 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07706954 0,11894119 ! T cell activation GO:0042110 168 81 1,000 0,07841736 0,12094369 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,07841736 0,12086621 ! response to nutrient GO:0007584 125 82 1,000 0,08008636 0,12335966 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0823429 0,12675434 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0823429 0,12667329 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0823429 0,12659235 ! superoxide anion generation GO:0042554 20 15 0,000 0,0823429 0,12651151 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0823429 0,12643078 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0823429 0,12635014 ! copper ion transport GO:0006825 20 15 0,000 0,0823429 0,12626962 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0823429 0,12618919 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0823429 0,12610886 ! sulfate transport GO:0008272 23 15 0,000 0,0823429 0,12602864 ! response to cAMP GO:0051591 22 15 0,000 0,0823429 0,12594852 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0823429 0,1258685 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0823429 0,12578859 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0823429 0,12570877 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0823429 0,12562906 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0823429 0,12554945 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0823429 0,12546993 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0823429 0,12539052 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0823429 0,12531121 ! vesicle coating GO:0006901 33 15 0,000 0,0823429 0,125232 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0823429 0,12515289 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0823429 0,12507388 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0823429 0,12499497 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0823429 0,12491616 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0823429 0,12483745 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0823429 0,12475883 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0823429 0,12468032 ! histone deacetylation GO:0016575 20 15 0,000 0,0823429 0,1246019 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0823429 0,12452359 ! tissue regeneration GO:0042246 26 15 0,000 0,0823429 0,12444537 ! water homeostasis GO:0030104 27 15 0,000 0,0823429 0,12436725 ! muscle maintenance GO:0046716 26 15 0,000 0,0823429 0,12428923 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0823429 0,1242113 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0823429 0,12413348 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0823429 0,12405575 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0823429 0,12397811 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0823429 0,12390058 ! cell killing GO:0001906 29 15 0,000 0,0823429 0,12382314 ! detection of bacterium GO:0016045 18 15 0,000 0,0823429 0,1237458 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0823429 0,12366856 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0823429 0,12359141 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0823429 0,12351436 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0823429 0,1234374 ! peptide hormone processing GO:0016486 23 15 0,000 0,0823429 0,12336054 ! negative regulation of growth GO:0045926 155 84 1,000 0,08345731 0,12495227 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08515891 0,12742061 ! response to inorganic substance GO:0010035 153 86 1,000 0,08687101 0,12990159 ! tube morphogenesis GO:0035239 176 86 1,000 0,08687101 0,12982091 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08758631 0,1308086 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08758631 0,13072746 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08758631 0,13064641 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08758631 0,13056547 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08758631 0,13048462 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08758631 0,13040388 ! bone remodeling GO:0046849 27 16 0,000 0,08758631 0,13032323 ! filopodium assembly GO:0046847 32 16 0,000 0,08758631 0,13024268 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08758631 0,13016224 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08758631 0,13008189 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08758631 0,13000164 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08758631 0,12992149 ! startle response GO:0001964 28 16 0,000 0,08758631 0,12984144 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08758631 0,12976149 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08758631 0,12968164 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08758631 0,12960188 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08758631 0,12952223 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08758631 0,12944267 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08758631 0,12936321 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08758631 0,12928384 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08758631 0,12920458 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08758631 0,12912541 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08758631 0,12904633 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08758631 0,12896736 ! fructose metabolic process GO:0006000 25 16 0,000 0,08758631 0,12888848 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08758631 0,1288097 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08758631 0,12873101 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08758631 0,12865242 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08758631 0,12857392 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08758631 0,12849553 ! axon cargo transport GO:0008088 43 16 0,000 0,08758631 0,12841722 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08758631 0,12833902 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08758631 0,1282609 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08758631 0,12818288 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08758631 0,12810496 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08758631 0,12802713 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08758631 0,1279494 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08758631 0,12787176 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08758631 0,12779422 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08758631 0,12771677 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08758631 0,12763941 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08758631 0,12756214 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08758631 0,12748497 ! defense response to virus GO:0051607 37 16 0,000 0,08758631 0,1274079 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,09206866 0,13384725 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09279993 0,13482888 ! metencephalon development GO:0022037 30 17 0,000 0,09279993 0,13474751 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09279993 0,13466624 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,09279993 0,13458507 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09279993 0,13450399 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09279993 0,13442302 ! signal complex assembly GO:0007172 41 17 0,000 0,09279993 0,13434214 ! endothelial cell migration GO:0043542 28 17 0,000 0,09279993 0,13426135 ! inositol metabolic process GO:0006020 28 17 0,000 0,09279993 0,13418067 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09279993 0,13410008 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09279993 0,13401959 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09279993 0,13393919 ! adult walking behavior GO:0007628 33 17 0,000 0,09279993 0,13385889 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09279993 0,13377869 ! heart looping GO:0001947 30 17 0,000 0,09279993 0,13369858 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09279993 0,13361857 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09279993 0,13353865 ! myoblast differentiation GO:0045445 45 17 0,000 0,09279993 0,13345883 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09279993 0,13337911 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09279993 0,13329948 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09279993 0,13321995 ! glycine metabolic process GO:0006544 28 17 0,000 0,09279993 0,13314051 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09279993 0,13306116 ! NAD metabolic process GO:0019674 29 17 0,000 0,09279993 0,13298191 ! membrane budding GO:0006900 37 17 0,000 0,09279993 0,13290276 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09279993 0,13282369 ! regulation of protein binding GO:0043393 33 17 0,000 0,09279993 0,13274473 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09279993 0,13266585 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09279993 0,13258707 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09279993 0,13250839 ! genitalia development GO:0048806 30 17 0,000 0,09279993 0,13242979 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09279993 0,13235129 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09279993 0,13227289 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09279993 0,13219457 ! steroid catabolic process GO:0006706 31 17 0,000 0,09279993 0,13211635 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09279993 0,13203822 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09279993 0,13196018 ! gas transport GO:0015669 25 17 0,000 0,09279993 0,13188224 ! organic cation transport GO:0015695 31 17 0,000 0,09279993 0,13180439 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09279993 0,13172663 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09279993 0,13164896 ! microspike assembly GO:0030035 36 17 0,000 0,09279993 0,13157138 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09279993 0,13149389 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09279993 0,1314165 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,09382108 0,13278443 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09798393 0,13859455 ! neuron maturation GO:0042551 42 18 0,000 0,09798393 0,13851312 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09798393 0,13843179 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09798393 0,13835055 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09798393 0,13826941 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09798393 0,13818836 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09798393 0,1381074 ! memory GO:0007613 31 18 0,000 0,09798393 0,13802654 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09798393 0,13794578 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09798393 0,13786511 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09798393 0,13778453 GO:0042744|hydrogen peroxide catabolic process, ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09798393 0,13770405 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09798393 0,13762366 ! response to retinoic acid GO:0032526 26 18 0,000 0,09798393 0,13754337 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,09798393 0,13746317 ! response to fungus GO:0009620 21 18 0,000 0,09798393 0,13738306 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09798393 0,13730305 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09798393 0,13722313 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09798393 0,1371433 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09798393 0,13706357 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09798393 0,13698393 ! vitamin transport GO:0051180 27 18 0,000 0,09798393 0,13690438 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09798393 0,13682492 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09798393 0,13674555 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09798393 0,13666628 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09798393 0,1365871 ! nerve development GO:0021675 28 18 0,000 0,09798393 0,13650801 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09798393 0,13642901 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,09913564 0,13795277 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,09913564 0,13787303 ! female pregnancy GO:0007565 164 94 1,000 0,1009257 0,14028148 ! transcription initiation GO:0006352 153 94 1,000 0,1009257 0,14020048 ! regulation of T cell activation GO:0050863 158 94 1,000 0,1009257 0,14011958 ! forebrain development GO:0030900 188 95 1,000 0,10272477 0,14253506 ! protein secretion GO:0009306 39 19 0,000 0,10313848 0,14302662 ! positive regulation of translation GO:0045727 30 19 0,000 0,10313848 0,14294423 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10313848 0,14286193 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10313848 0,14277974 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10313848 0,14269763 ! skin development GO:0043588 36 19 0,000 0,10313848 0,14261562 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10313848 0,1425337 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10313848 0,14245188 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10313848 0,14237015 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10313848 0,14228852 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10313848 0,14220698 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10313848 0,14212553 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10313848 0,14204418 ! heme metabolic process GO:0042168 36 19 0,000 0,10313848 0,14196292 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10313848 0,14188175 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10313848 0,14180067 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10313848 0,14171969 ! peptide cross-linking GO:0018149 37 19 0,000 0,10313848 0,1416388 ! protein export from nucleus GO:0006611 36 19 0,000 0,10313848 0,141558 ! heart process GO:0003015 30 19 0,000 0,10313848 0,1414773 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10313848 0,14139668 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10313848 0,14131616 ! visual learning GO:0008542 36 19 0,000 0,10313848 0,14123573 ! G1 phase GO:0051318 40 19 0,000 0,10313848 0,14115539 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10313848 0,14107514 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10313848 0,14099499 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10313848 0,14091492 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10313848 0,14083495 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10313848 0,14075507 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10313848 0,14067527 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10313848 0,14059557 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10313848 0,14051596 ! cilium assembly GO:0042384 37 19 0,000 0,10313848 0,14043643 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10313848 0,140357 ! leukocyte differentiation GO:0002521 202 96 1,000 0,10453268 0,1421739 ! detection of stimulus GO:0051606 151 96 1,000 0,10453268 0,14209357 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10826374 0,14708219 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10826374 0,14699919 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10826374 0,14691628 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10826374 0,14683346 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10826374 0,14675074 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10826374 0,14666811 ! response to vitamin GO:0033273 31 20 0,000 0,10826374 0,14658557 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10826374 0,14650313 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10826374 0,14642078 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10826374 0,14633852 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10826374 0,14625635 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10826374 0,14617428 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10826374 0,1460923 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10826374 0,14601041 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10826374 0,14592861 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10826374 0,1458469 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10826374 0,14576528 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10826374 0,14568376 ! body fluid secretion GO:0007589 31 20 0,000 0,10826374 0,14560233 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10826374 0,14552099 ! peptide secretion GO:0002790 35 20 0,000 0,10826374 0,14543973 ! stem cell differentiation GO:0048863 53 20 0,000 0,10826374 0,14535857 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10826374 0,1452775 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10826374 0,14519652 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10826374 0,14511563 ! sensory perception of pain GO:0019233 30 20 0,000 0,10826374 0,14503484 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10826374 0,14495413 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10826374 0,14487351 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10826374 0,14479298 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10826374 0,14471254 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10826374 0,14463218 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10826374 0,14455192 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10826374 0,14447175 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10826374 0,14439167 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10826374 0,14431167 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10826374 0,14423176 ! actin filament-based movement GO:0030048 43 20 0,000 0,10826374 0,14415194 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10826374 0,14407221 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10826374 0,14399257 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10826374 0,14391302 ! regulation of cell killing GO:0031341 42 21 0,000 0,11335989 0,15060402 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11335989 0,15052091 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11335989 0,15043789 ! hormone secretion GO:0046879 38 21 0,000 0,11335989 0,15035495 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11335989 0,15027211 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11335989 0,15018936 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11335989 0,15010671 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11335989 0,15002414 ! axis specification GO:0009798 38 21 0,000 0,11335989 0,14994166 ! ovarian follicle development GO:0001541 35 21 0,000 0,11335989 0,14985928 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11335989 0,14977698 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11335989 0,14969478 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11335989 0,14961266 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11335989 0,14953064 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11335989 0,1494487 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11335989 0,14936686 ! cytolysis GO:0019835 24 21 0,000 0,11335989 0,1492851 ! vasodilation GO:0042311 39 21 0,000 0,11335989 0,14920344 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11335989 0,14912186 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11335989 0,14904037 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11335989 0,14895898 ! DNA modification GO:0006304 34 21 0,000 0,11335989 0,14887767 ! collagen fibril organization GO:0030199 59 21 0,000 0,11335989 0,14879645 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11335989 0,14871531 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11335989 0,14863427 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11335989 0,14855331 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11335989 0,14847245 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11335989 0,14839167 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11335989 0,14831098 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11335989 0,14823037 ! collagen catabolic process GO:0030574 28 21 0,000 0,11335989 0,14814986 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11335989 0,14806943 ! gut development GO:0048565 39 21 0,000 0,11335989 0,14798909 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11842707 0,15452036 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11842707 0,15443661 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11842707 0,15435295 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11842707 0,15426938 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11842707 0,1541859 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11842707 0,15410251 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11842707 0,15401921 ! regeneration GO:0031099 41 22 0,000 0,11842707 0,153936 ! keratinization GO:0031424 28 22 0,000 0,11842707 0,15385288 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11842707 0,15376985 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11842707 0,15368692 ! sensory perception of taste GO:0050909 28 22 0,000 0,11842707 0,15360407 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11842707 0,1535213 ! vacuolar transport GO:0007034 36 22 0,000 0,11842707 0,15343863 ! lysosome organization GO:0007040 41 22 0,000 0,11842707 0,15335605 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11842707 0,15327356 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11842707 0,15319115 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11842707 0,15310883 ! fucose metabolic process GO:0006004 39 22 0,000 0,11842707 0,15302661 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11842707 0,15294447 ! ureteric bud development GO:0001657 43 22 0,000 0,11842707 0,15286241 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11842707 0,15278045 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11842707 0,15269857 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11842707 0,15261679 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11842707 0,15253509 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11842707 0,15245347 ! sarcomere organization GO:0045214 30 22 0,000 0,11842707 0,15237195 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,11842707 0,15229051 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11842707 0,15220916 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11842707 0,15212789 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11842707 0,15204671 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11842707 0,15196562 ! protein stabilization GO:0050821 39 22 0,000 0,11842707 0,15188462 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,12346547 0,15826208 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12346547 0,15817781 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12346547 0,15809363 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12346547 0,15800953 ! gluconeogenesis GO:0006094 33 23 0,000 0,12346547 0,15792553 ! viral genome replication GO:0019079 41 23 0,000 0,12346547 0,15784162 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12346547 0,15775779 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12346547 0,15767406 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12346547 0,15759041 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12346547 0,15750685 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12346547 0,15742338 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12346547 0,15734 ! visual behavior GO:0007632 42 23 0,000 0,12346547 0,15725671 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,12346547 0,1571735 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12346547 0,15709039 ! response to ethanol GO:0045471 46 23 0,000 0,12346547 0,15700736 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12346547 0,15692442 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12346547 0,15684156 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12346547 0,1567588 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12346547 0,15667612 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12346547 0,15659353 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12346547 0,15651102 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,12346547 0,15642861 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12346547 0,15634628 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12346547 0,15626403 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12346547 0,15618187 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12346547 0,1560998 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12346547 0,15601782 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12346547 0,15593592 ! fatty acid transport GO:0015908 44 23 0,000 0,12346547 0,1558541 ! platelet activation GO:0030168 37 23 0,000 0,12346547 0,15577238 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12346547 0,15569074 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12346547 0,15560918 ! hormone transport GO:0009914 40 23 0,000 0,12346547 0,15552771 ! cell-cell recognition GO:0009988 25 23 0,000 0,12346547 0,15544632 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12346547 0,15536502 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12346547 0,15528381 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12346547 0,15520268 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12346547 0,15512163 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12346547 0,15504067 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,12847524 0,16124748 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12847524 0,16116341 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12847524 0,16107943 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12847524 0,16099553 ! vesicle docking GO:0048278 47 24 0,000 0,12847524 0,16091172 ! spinal cord development GO:0021510 47 24 0,000 0,12847524 0,160828 ! vacuole organization GO:0007033 43 24 0,000 0,12847524 0,16074437 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12847524 0,16066082 ! digestive system process GO:0022600 39 24 0,000 0,12847524 0,16057736 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12847524 0,16049399 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,12847524 0,1604107 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12847524 0,1603275 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12847524 0,16024439 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12847524 0,16016136 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12847524 0,16007842 ! membrane depolarization GO:0051899 39 24 0,000 0,12847524 0,15999556 ! pentose metabolic process GO:0019321 35 24 0,000 0,12847524 0,15991279 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12847524 0,15983011 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12847524 0,15974751 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12847524 0,15966499 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12847524 0,15958256 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12847524 0,15950022 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12847524 0,15941796 ! regulation of amine transport GO:0051952 40 24 0,000 0,12847524 0,15933579 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13345654 0,16542835 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,13345654 0,16534317 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13345654 0,16525807 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13345654 0,16517306 ! phototransduction GO:0007602 33 25 0,000 0,13345654 0,16508814 ! sperm motility GO:0030317 31 25 0,000 0,13345654 0,1650033 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13345654 0,16491856 ! receptor metabolic process GO:0043112 46 25 0,000 0,13345654 0,1648339 ! chromosome condensation GO:0030261 45 25 0,000 0,13345654 0,16474932 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13345654 0,16466484 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13345654 0,16458044 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13345654 0,16449612 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13345654 0,16441189 ! interaction with host GO:0051701 62 25 0,000 0,13345654 0,16432775 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13345654 0,1642437 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13345654 0,16415973 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13345654 0,16407585 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13345654 0,16399205 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13345654 0,16390834 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13345654 0,16382471 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13345654 0,16374117 ! telomere organization GO:0032200 43 25 0,000 0,13345654 0,16365771 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13345654 0,16357434 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13345654 0,16349105 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13840953 0,16947243 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13840953 0,16938623 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13840953 0,16930012 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13840953 0,16921409 ! initiation of viral infection GO:0019059 57 26 0,000 0,13840953 0,16912815 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13840953 0,1690423 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13840953 0,16895654 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13840953 0,16887086 ! tube lumen formation GO:0035148 50 26 0,000 0,13840953 0,16878527 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13840953 0,16869976 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13840953 0,16861435 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13840953 0,16852901 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,13840953 0,16844377 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13840953 0,16835861 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13840953 0,16827354 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13840953 0,16818855 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13840953 0,16810365 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13840953 0,16801884 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,13840953 0,16793411 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13840953 0,16784946 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13840953 0,1677649 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13840953 0,16768043 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13840953 0,16759604 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13840953 0,16751174 ! neuron fate commitment GO:0048663 48 27 0,000 0,14333438 0,17338487 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14333438 0,17329775 ! iron ion transport GO:0006826 59 27 0,000 0,14333438 0,17321071 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14333438 0,17312375 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14333438 0,17303689 ! fat cell differentiation GO:0045444 50 27 0,000 0,14333438 0,17295011 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14333438 0,17286342 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14333438 0,17277681 ! autophagy GO:0006914 41 27 0,000 0,14333438 0,17269029 ! male gonad development GO:0008584 44 27 0,000 0,14333438 0,17260386 ! primary neural tube formation GO:0014020 51 27 0,000 0,14333438 0,17251752 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14333438 0,17243126 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14333438 0,17234508 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14333438 0,172259 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14333438 0,172173 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14333438 0,17208708 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14333438 0,17200125 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14823124 0,17778881 ! circadian rhythm GO:0007623 50 28 0,000 0,14823124 0,17770023 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14823124 0,17761173 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14823124 0,17752332 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14823124 0,177435 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14823124 0,17734677 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14823124 0,17725863 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14823124 0,17717057 ! synaptogenesis GO:0007416 42 28 0,000 0,14823124 0,1770826 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,14823124 0,17699472 ! lipid oxidation GO:0034440 43 28 0,000 0,14823124 0,17690692 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14823124 0,17681921 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14823124 0,17673159 ! translational initiation GO:0006413 65 29 0,000 0,15310027 0,18244638 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15310027 0,18235606 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15310027 0,18226583 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15310027 0,18217569 ! catechol metabolic process GO:0009712 54 29 0,000 0,15310027 0,18208564 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15310027 0,18199567 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15310027 0,1819058 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15310027 0,18181601 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15310027 0,18172632 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15310027 0,18163671 ! cell fate determination GO:0001709 60 29 0,000 0,15310027 0,18154719 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15310027 0,18145775 ! detection of light stimulus GO:0009583 38 29 0,000 0,15310027 0,18136841 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15310027 0,18127915 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15310027 0,18118999 ! regulation of coagulation GO:0050818 46 29 0,000 0,15310027 0,18110091 ! phenol metabolic process GO:0018958 55 30 0,000 0,15794162 0,1867359 ! zinc ion transport GO:0006829 45 30 0,000 0,15794162 0,18664418 ! membrane docking GO:0022406 61 30 0,000 0,15794162 0,18655255 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15794162 0,18646101 ! cell junction assembly GO:0034329 78 30 0,000 0,15794162 0,18636957 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15794162 0,18627821 ! acute-phase response GO:0006953 49 30 0,000 0,15794162 0,18618694 ! myofibril assembly GO:0030239 47 30 0,000 0,15794162 0,18609576 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15794162 0,18600467 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15794162 0,18591367 ! phospholipid transport GO:0015914 51 30 0,000 0,15794162 0,18582276 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15794162 0,18573194 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15794162 0,18564121 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15794162 0,18555056 ! eye morphogenesis GO:0048592 60 30 0,000 0,15794162 0,18546 ! regulation of B cell activation GO:0050864 50 30 0,000 0,15794162 0,18536953 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16275546 0,19092621 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16275546 0,19083316 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16275546 0,19074021 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16275546 0,19064735 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16275546 0,19055457 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16275546 0,19046189 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16275546 0,1903693 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16275546 0,1902768 ! ovulation cycle process GO:0022602 49 31 0,000 0,16275546 0,19018438 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16275546 0,19009206 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16275546 0,18999983 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16275546 0,18990769 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16275546 0,18981563 ! mesoderm formation GO:0001707 69 31 0,000 0,16275546 0,18972367 ! natural killer cell activation GO:0030101 45 31 0,000 0,16275546 0,18963179 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16275546 0,18954 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16275546 0,18944831 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16275546 0,1893567 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16754195 0,19483128 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16754195 0,19473716 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16754195 0,19464313 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16754195 0,19454919 ! cholesterol transport GO:0030301 56 32 0,000 0,16754195 0,19445534 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16754195 0,19436158 ! spliceosome assembly GO:0000245 67 32 0,000 0,16754195 0,19426791 ! spindle organization GO:0007051 46 32 0,000 0,16754195 0,19417434 ! metanephros development GO:0001656 74 32 0,000 0,16754195 0,19408085 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16754195 0,19398745 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,16754195 0,19389414 ! muscle cell development GO:0055001 49 32 0,000 0,16754195 0,19380092 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16754195 0,1937078 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16754195 0,19361476 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16754195 0,19352181 ! ovulation cycle GO:0042698 51 32 0,000 0,16754195 0,19342895 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16754195 0,19333617 ! hindbrain development GO:0030902 61 32 0,000 0,16754195 0,19324349 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,16754195 0,1931509 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16754195 0,19305839 ! gene silencing GO:0016458 65 32 0,000 0,16754195 0,19296597 ! post-embryonic development GO:0009791 69 33 0,000 0,17230122 0,19835251 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17230122 0,19825765 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17230122 0,19816288 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17230122 0,1980682 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17230122 0,19797361 ! cell fate specification GO:0001708 52 33 0,000 0,17230122 0,19787911 ! sterol transport GO:0015918 57 33 0,000 0,17230122 0,1977847 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17230122 0,19769038 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17230122 0,19759616 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17230122 0,19750202 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17703344 0,20282975 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17703344 0,20273321 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17703344 0,20263676 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,17703344 0,2025404 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17703344 0,20244414 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17703344 0,20234796 ! mismatch repair GO:0006298 46 34 0,000 0,17703344 0,20225188 ! spermatid development GO:0007286 63 34 0,000 0,17703344 0,20215589 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17703344 0,20205999 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17703344 0,20196418 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,17703344 0,20186847 ! regulation of muscle development GO:0048634 70 35 0,000 0,18173877 0,2071357 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18173877 0,20703763 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18173877 0,20693965 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,18173877 0,20684176 ! odontogenesis GO:0042476 66 35 0,000 0,18173877 0,20674396 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18173877 0,20664625 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18173877 0,20654864 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,18173877 0,20645112 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18173877 0,20635369 ! neural tube formation GO:0001841 67 35 0,000 0,18173877 0,20625636 ! vesicle localization GO:0051648 64 35 0,000 0,18173877 0,20615911 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,18641734 0,2113667 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18641734 0,21126714 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18641734 0,21116767 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18641734 0,2110683 ! cell junction organization GO:0034330 86 36 0,000 0,18641734 0,21096902 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18641734 0,21086983 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,18641734 0,21077074 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18641734 0,21067174 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18641734 0,21057283 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18641734 0,21047402 ! aerobic respiration GO:0009060 55 36 0,000 0,18641734 0,21037529 ! embryonic organ development GO:0048568 57 36 0,000 0,18641734 0,21027667 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18641734 0,21017813 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19106932 0,21532215 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19106932 0,21522134 ! meiosis I GO:0007127 65 37 0,000 0,19106932 0,21512063 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19106932 0,21502002 ! sister chromatid segregation GO:0000819 58 37 0,000 0,19106932 0,21491949 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19106932 0,21481906 ! organic anion transport GO:0015711 68 37 0,000 0,19106932 0,21471873 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19106932 0,21461848 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19106932 0,21451834 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19106932 0,21441828 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,19106932 0,21431832 ! spermatid differentiation GO:0048515 66 37 0,000 0,19106932 0,21421845 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19569486 0,2193022 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,19569486 0,21920011 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19569486 0,21909811 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19569486 0,2189962 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,19569486 0,21889439 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,19569486 0,21879267 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19569486 0,21869105 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19569486 0,21858952 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19569486 0,21848809 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19569486 0,21838675 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,19569486 0,2182855 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 0,000 0,2002941 0,22331214 ! organic ether metabolic process GO:0018904 55 39 0,000 0,2002941 0,22320871 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,2002941 0,22310537 ! ion transmembrane transport GO:0034220 66 39 0,000 0,2002941 0,22300213 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,2002941 0,22289898 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,2002941 0,22279593 ! RNA modification GO:0009451 57 39 0,000 0,2002941 0,22269297 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,20486719 0,22767226 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,20486719 0,22756715 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20486719 0,22746214 ! feeding behavior GO:0007631 59 40 0,000 0,20486719 0,22735722 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,20486719 0,2272524 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20486719 0,22714767 ! maintenance of protein location GO:0045185 91 40 0,000 0,20486719 0,22704305 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20941428 0,23197548 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,20941428 0,23186873 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20941428 0,23176207 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,20941428 0,23165552 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,20941428 0,23154906 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,20941428 0,2314427 ! polyol metabolic process GO:0019751 66 41 0,000 0,20941428 0,23133643 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,20941428 0,23123027 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21393551 0,23611415 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21393551 0,23600589 ! regulation of tube size GO:0035150 71 42 0,000 0,21393551 0,23589773 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21393551 0,23578967 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21393551 0,23568171 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21393551 0,23557384 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21393551 0,23546608 ! neuron migration GO:0001764 79 42 0,000 0,21393551 0,23535841 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21393551 0,23525084 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,21843105 0,24008456 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,21843105 0,23997493 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21843105 0,2398654 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,21843105 0,23975597 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,21843105 0,23964665 ! neural tube development GO:0021915 77 43 0,000 0,21843105 0,23953742 ! striated muscle contraction GO:0006941 77 43 0,000 0,21843105 0,23942829 ! phagocytosis GO:0006909 90 43 0,000 0,21843105 0,23931926 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21843105 0,23921033 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22290102 0,24399447 ! male sex differentiation GO:0046661 76 44 0,000 0,22290102 0,24388351 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22290102 0,24377266 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,22290102 0,2436619 ! maintenance of location in cell GO:0051651 97 44 0,000 0,22290102 0,24355125 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22734557 0,2482948 ! glycolysis GO:0006096 65 45 0,000 0,22734557 0,24818214 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,22734557 0,24806959 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22734557 0,24795713 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22734557 0,24784478 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22734557 0,24773253 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22734557 0,24762039 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23176485 0,25231956 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,23176485 0,25220544 ! response to calcium ion GO:0051592 81 47 0,000 0,236159 0,25687095 ! endosome transport GO:0016197 108 47 0,000 0,236159 0,25675488 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,236159 0,25663891 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,236159 0,25652304 ! JNK cascade GO:0007254 91 47 0,000 0,236159 0,25640728 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,236159 0,25629163 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24052816 0,26091557 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24052816 0,26079799 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24052816 0,26068051 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24052816 0,26056314 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24052816 0,26044588 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24487247 0,26503066 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24487247 0,26491149 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24487247 0,26479243 ! regulation of ion transport GO:0043269 77 49 0,000 0,24487247 0,26467348 ! peptide metabolic process GO:0006518 76 49 0,000 0,24487247 0,26455463 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24487247 0,26443589 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24487247 0,26431725 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24487247 0,26419873 ! neuromuscular process GO:0050905 99 50 0,000 0,24919208 0,26873874 ! inner ear development GO:0048839 79 50 0,000 0,24919208 0,26861834 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,24919208 0,26849805 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,24919208 0,26837786 ! viral infectious cycle GO:0019058 99 51 0,000 0,25348712 0,27288143 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,25348712 0,27275939 ! excretion GO:0007588 83 51 0,000 0,25348712 0,27263746 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25348712 0,27251564 ! chromatin remodeling GO:0006338 109 51 0,000 0,25348712 0,27239393 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,25348712 0,27227232 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,25348712 0,27215083 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,25348712 0,27202944 ! membrane fusion GO:0006944 110 52 0,000 0,25775773 0,27648912 ! amino acid activation GO:0043038 92 52 0,000 0,25775773 0,27636591 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26200405 0,28079365 ! RNA catabolic process GO:0006401 93 53 0,000 0,26200405 0,28066863 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26200405 0,28054372 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26200405 0,28041892 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26200405 0,28029424 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26200405 0,28016966 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26200405 0,2800452 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26622622 0,28443174 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,26622622 0,2843055 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26622622 0,28417936 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26622622 0,28405334 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26622622 0,28392743 ! chloride transport GO:0006821 90 55 0,000 0,27042437 0,28827693 ! glucose catabolic process GO:0006007 82 55 0,000 0,27042437 0,28814927 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27042437 0,28802171 ! gastrulation GO:0007369 112 55 0,000 0,27042437 0,28789427 ! heart morphogenesis GO:0003007 97 55 0,000 0,27042437 0,28776694 ! RNA elongation GO:0006354 79 55 0,000 0,27042437 0,28763972 ! nuclear export GO:0051168 97 55 0,000 0,27042437 0,28751261 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27459865 0,29182171 ! sensory perception of smell GO:0007608 80 56 0,000 0,27459865 0,29169287 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27459865 0,29156414 ! proton transport GO:0015992 94 56 0,000 0,27459865 0,29143553 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,27459865 0,29130703 ! maintenance of location GO:0051235 118 57 0,000 0,27874917 0,29557978 ! hydrogen transport GO:0006818 97 58 0,000 0,28287609 0,29982373 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28287609 0,29969171 ! adult behavior GO:0030534 99 58 0,000 0,28287609 0,29955981 ! positive regulation of secretion GO:0051047 95 59 0,000 0,28697953 0,30377156 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28697953 0,30363797 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28697953 0,30350451 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,28697953 0,30337116 ! establishment of organelle localization GO:0051656 109 59 0,000 0,28697953 0,30323792 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,29105963 0,30741416 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,29105963 0,30727927 ! camera-type eye development GO:0043010 116 60 0,000 0,29105963 0,3071445 ! kidney development GO:0001822 122 60 0,000 0,29105963 0,30700985 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29511651 0,31115264 ! mesoderm development GO:0007498 119 61 0,000 0,29511651 0,31101635 ! tRNA processing GO:0008033 89 61 0,000 0,29511651 0,31088018 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29511651 0,31074413 ! viral reproductive process GO:0022415 126 62 0,000 0,29915031 0,31485374 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29915031 0,31471607 ! regulation of mitosis GO:0007088 105 63 0,000 0,30316117 0,31879623 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,30316117 0,31865695 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,30316117 0,3185178 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30316117 0,31837877 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,3071492 0,32242625 ! cell redox homeostasis GO:0045454 102 64 0,000 0,3071492 0,32228564 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,3071492 0,32214515 ! single fertilization GO:0007338 75 64 0,000 0,3071492 0,32200478 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31111454 0,32601985 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,31111454 0,32587792 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,31111454 0,32573611 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,31505731 0,3297207 ! actin filament organization GO:0007015 148 66 0,000 0,31505731 0,32957734 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31505731 0,32943411 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31505731 0,329291 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,31897765 0,33324369 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,31897765 0,33309906 ! activation of MAPK activity GO:0000187 115 67 0,000 0,31897765 0,33295455 ! chromosome segregation GO:0007059 113 67 0,000 0,31897765 0,33281016 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,31897765 0,3326659 ! hexose catabolic process GO:0019320 104 67 0,000 0,31897765 0,33252176 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,31897765 0,33237775 ! activation of immune response GO:0002253 105 67 0,000 0,31897765 0,33223387 ! amino acid transport GO:0006865 125 68 0,000 0,32287568 0,33614837 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32287568 0,33600298 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,32287568 0,33585771 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,32287568 0,33571257 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32287568 0,33556756 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,32287568 0,33542267 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,32675153 0,33930263 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,32675153 0,33915625 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32675153 0,33901 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32675153 0,33886387 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32675153 0,33871787 ! appendage morphogenesis GO:0035107 135 70 0,000 0,33060532 0,34256521 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,33443718 0,34638651 ! appendage development GO:0048736 136 71 0,000 0,33443718 0,34623746 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,33443718 0,34608854 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,33443718 0,34593975 ! regulation of immune effector process GO:0002697 137 71 0,000 0,33443718 0,34579109 ! acute inflammatory response GO:0002526 113 72 0,000 0,33824723 0,34958026 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,33824723 0,34943016 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,33824723 0,34928019 ! regulation of blood pressure GO:0008217 125 73 0,000 0,3420356 0,35304061 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,3420356 0,35288922 ! fertilization GO:0009566 90 73 0,000 0,3420356 0,35273796 ! transition metal ion transport GO:0000041 126 74 0,000 0,34580241 0,35646983 ! neurotransmitter transport GO:0006836 123 74 0,000 0,34580241 0,35631717 ! exocytosis GO:0006887 133 74 0,000 0,34580241 0,35616464 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,34580241 0,35601223 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,34580241 0,35585996 ! eye development GO:0001654 143 74 0,000 0,34580241 0,35570782 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34954777 0,35940681 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34954777 0,35925328 ! rhythmic process GO:0048511 128 75 0,000 0,34954777 0,35909989 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35327182 0,3627708 ! defense response to bacterium GO:0042742 89 76 0,000 0,35327182 0,36261604 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,35327182 0,3624614 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35327182 0,3623069 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35697466 0,36594846 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35697466 0,36579261 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,35697466 0,36563688 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,35697466 0,36548129 ! blood coagulation GO:0007596 146 78 0,000 0,36065643 0,36909374 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,36065643 0,36893681 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,36065643 0,36878002 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36431724 0,37236503 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,36431724 0,37220692 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,36431724 0,37204893 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,36431724 0,37189109 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,36795721 0,37544744 ! muscle cell differentiation GO:0042692 159 80 0,000 0,36795721 0,37528828 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,36795721 0,37512926 ! inorganic anion transport GO:0015698 138 80 0,000 0,36795721 0,37497038 ! digestion GO:0007586 112 81 0,000 0,37157646 0,37849829 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,37157646 0,37833812 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,37517511 0,38184065 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37517511 0,3816792 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,37517511 0,38151788 ! regulation of lyase activity GO:0051339 160 83 0,000 0,37875326 0,38499381 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,38231104 0,3884461 ! hemostasis GO:0007599 158 84 0,000 0,38231104 0,38828213 ! regulation of ligase activity GO:0051340 142 84 0,000 0,38231104 0,3881183 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,38231104 0,38795461 ! response to unfolded protein GO:0006986 131 85 0,000 0,38584857 0,39137928 ! nucleosome assembly GO:0006334 122 85 0,000 0,38584857 0,39121435 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,38584857 0,39104956 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38936595 0,3944482 ! chromatin assembly GO:0031497 124 86 0,000 0,38936595 0,39428219 ! alcohol catabolic process GO:0046164 130 86 0,000 0,38936595 0,39411631 ! amine transport GO:0015837 155 86 0,000 0,38936595 0,39395058 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,39286331 0,39732203 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,39286331 0,39715509 ! cellular respiration GO:0045333 135 88 0,000 0,39634075 0,40050224 ! regulation of neurological system process GO:0031644 148 88 0,000 0,39634075 0,4003341 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39634075 0,40016611 ! cellular defense response GO:0006968 114 89 0,000 0,39979838 0,4034878 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,40323633 0,40678684 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,40323633 0,40661635 ! sterol metabolic process GO:0016125 152 91 0,000 0,4066547 0,40989158 ! response to protein stimulus GO:0051789 149 91 0,000 0,4066547 0,40971994 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,4066547 0,40954843 ! nucleosome organization GO:0034728 138 92 0,000 0,4100536 0,41279873 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,4100536 0,41262608 ! vitamin metabolic process GO:0006766 139 92 0,000 0,4100536 0,41245358 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,41343314 0,41567912 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,41343314 0,41550549 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,41679344 0,41870773 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,42013459 0,42188808 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42345672 0,42504667 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42345672 0,42486942 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42345672 0,42469232 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42675992 0,42782682 ! hormone metabolic process GO:0042445 157 97 0,000 0,42675992 0,42764863 ! response to virus GO:0009615 160 98 0,000 0,43004431 0,43076045 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43004431 0,43058119 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43004431 0,43040208 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,43330999 0,43349016 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,43330999 0,43330999