pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6348-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein sumoylation GO:0016925 17 10 6,000 9,733E-15 2,378E-11 ! induction of positive chemotaxis GO:0050930 17 9 3,000 8,214E-08 1,003E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,145E-07 9,324E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 3,188E-07 1,947E-04 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of protein complex assembly GO:0031334 34 18 3,000 1,924E-06 9,401E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 2,611E-06 1,063E-03 ! negative regulation of axon extension GO:0030517 24 6 2,000 2,611E-06 9,114E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 3,022E-06 9,229E-04 ! inactivation of MAPK activity GO:0000188 45 22 3,000 4,526E-06 1,229E-03 ! positive regulation of locomotion GO:0040017 44 22 3,000 4,526E-06 1,106E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of protein export from nucleus GO:0046825 10 7 2,000 4,553E-06 1,011E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 4,553E-06 9,268E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 5,457E-06 1,026E-03 ! mitochondrion organization GO:0007005 159 87 5,000 5,941E-06 1,037E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 7,257E-06 1,182E-03 ! ER overload response GO:0006983 13 8 2,000 7,257E-06 1,108E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 7,257E-06 1,043E-03 ! protein import into nucleus, translocation GO:0000060 51 25 3,000 7,734E-06 1,05E-03 ! regulation of behavior GO:0050795 48 25 3,000 7,734E-06 9,944E-04 ! regulation of cell morphogenesis GO:0022604 243 93 5,000 8,743E-06 1,068E-03 ! negative regulation of cell development GO:0010721 83 26 3,000 9,104E-06 1,059E-03 GO:0050768|negative regulation of neurogenesis, ! response to UV GO:0009411 120 55 4,000 9,417E-06 1,046E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,064E-05 1,131E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,084E-05 1,104E-03 ! mitochondrion localization GO:0051646 18 9 2,000 1,084E-05 1,06E-03 ! regulation of protein localization GO:0032880 188 97 5,000 1,114E-05 1,047E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 1,543E-05 1,396E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,543E-05 1,347E-03 ! negative regulation of transcription regulator activity GO:0090048 57 30 3,000 1,642E-05 1,384E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,114E-05 1,722E-03 ! L-serine metabolic process GO:0006563 21 11 2,000 2,114E-05 1,666E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,114E-05 1,614E-03 ! negative regulation of axonogenesis GO:0050771 37 11 2,000 2,114E-05 1,565E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,114E-05 1,519E-03 GO:0010829|negative regulation of glucose transport, ! regulation of axonogenesis GO:0050770 86 33 3,000 2,423E-05 1,691E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 3,000 2,735E-05 1,856E-03 ! negative regulation of DNA binding GO:0043392 67 36 3,000 3,446E-05 2,276E-03 ! negative regulation of cell projection organization GO:0031345 42 13 2,000 3,637E-05 2,338E-03 ! response to X-ray GO:0010165 28 13 2,000 3,637E-05 2,278E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 3,637E-05 2,221E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 4,284E-05 2,553E-03 ! regulation of transcription factor activity GO:0051090 137 75 4,000 4,301E-05 2,502E-03 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 4,611E-05 2,62E-03 ! response to gamma radiation GO:0010332 30 14 2,000 4,611E-05 2,56E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 4,611E-05 2,503E-03 ! regulation of axon extension GO:0030516 43 14 2,000 4,611E-05 2,449E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 4,611E-05 2,397E-03 ! regulation of neuron projection development GO:0010975 102 39 3,000 4,755E-05 2,42E-03 ! negative regulation of binding GO:0051100 71 39 3,000 4,755E-05 2,371E-03 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 3,000 4,755E-05 2,323E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 5,742E-05 2,751E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 7,693E-05 3,614E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 8,41E-05 3,876E-03 ! regulation of survival gene product expression GO:0045884 38 17 2,000 8,517E-05 3,853E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 8,517E-05 3,783E-03 ! pigmentation GO:0043473 103 46 3,000 9,174E-05 4,002E-03 ! regulation of DNA binding GO:0051101 167 89 4,000 9,764E-05 4,185E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 9,987E-05 4,207E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,018E-04 4,216E-03 ! DNA integration GO:0015074 32 18 2,000 1,018E-04 4,146E-03 ! gland development GO:0048732 220 91 4,000 1,085E-04 4,345E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,085E-04 4,276E-03 ! cellular pigmentation GO:0033059 37 19 2,000 1,205E-04 4,671E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 1,274E-04 4,864E-03 ! regulation of cell projection organization GO:0031344 135 51 3,000 1,377E-04 5,176E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,412E-04 5,226E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,412E-04 5,148E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 32 20 2,000 1,412E-04 5,072E-03 ! cartilage development GO:0051216 99 53 3,000 1,601E-04 5,668E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,641E-04 5,727E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,641E-04 5,646E-03 ! positive regulation of protein catabolic process GO:0045732 44 22 2,000 1,893E-04 6,423E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 1,893E-04 6,335E-03 ! cell aging GO:0007569 48 22 2,000 1,893E-04 6,249E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 1,893E-04 6,166E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,169E-04 6,971E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,469E-04 7,834E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 2,469E-04 7,733E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,469E-04 7,635E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,581E-04 7,882E-03 ! hypothalamus development GO:0021854 9 5 1,000 2,581E-04 7,785E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,581E-04 7,69E-03 ! negative chemotaxis GO:0050919 16 5 1,000 2,581E-04 7,597E-03 ! anagen GO:0042640 7 5 1,000 2,581E-04 7,507E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,581E-04 7,419E-03 ! microvillus organization GO:0032528 8 5 1,000 2,581E-04 7,332E-03 GO:0030033|microvillus assembly, ! melanin biosynthetic process from tyrosine GO:0006583 8 5 1,000 2,581E-04 7,248E-03 ! response to food GO:0032094 6 5 1,000 2,581E-04 7,166E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,581E-04 7,085E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 2,581E-04 7,007E-03 ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 2,581E-04 6,93E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,581E-04 6,854E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 2,581E-04 6,781E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! response to cadmium ion GO:0046686 7 5 1,000 2,581E-04 6,708E-03 ! decidualization GO:0046697 11 5 1,000 2,581E-04 6,638E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 2,581E-04 6,569E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,581E-04 6,501E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,581E-04 6,435E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 2,581E-04 6,37E-03 GO:0022011|myelination in the peripheral nervous system, ! vasculogenesis GO:0001570 49 25 2,000 2,795E-04 6,829E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 2,795E-04 6,761E-03 ! negative regulation of DNA replication GO:0008156 45 25 2,000 2,795E-04 6,695E-03 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 2,942E-04 6,979E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 3,129E-04 7,351E-03 ! myelination GO:0042552 50 26 2,000 3,148E-04 7,324E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 3,148E-04 7,255E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 3,148E-04 7,187E-03 ! blastocyst development GO:0001824 50 26 2,000 3,148E-04 7,121E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,325E-04 7,452E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 3,325E-04 7,384E-03 ! short-chain fatty acid metabolic process GO:0046459 8 6 1,000 3,859E-04 8,493E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 3,859E-04 8,417E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 3,859E-04 8,342E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,859E-04 8,269E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 3,859E-04 8,197E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 14 6 1,000 3,859E-04 8,127E-03 ! astrocyte development GO:0014002 16 6 1,000 3,859E-04 8,057E-03 ! response to copper ion GO:0046688 10 6 1,000 3,859E-04 7,989E-03 ! hair follicle maturation GO:0048820 8 6 1,000 3,859E-04 7,922E-03 ! Schwann cell development GO:0014044 15 6 1,000 3,859E-04 7,856E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 3,859E-04 7,791E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,859E-04 7,727E-03 ! maternal placenta development GO:0001893 12 6 1,000 3,859E-04 7,664E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 3,937E-04 7,756E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 4,374E-04 8,549E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 4,435E-04 8,598E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 4,435E-04 8,53E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 4,685E-04 8,941E-03 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 4,842E-04 9,17E-03 ! ensheathment of neurons GO:0007272 64 31 2,000 5,341E-04 0,01003678 GO:0008366|axon ensheathment, ! regulation of helicase activity GO:0051095 16 7 1,000 5,384E-04 0,01004068 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 5,384E-04 9,965E-03 ! prostate gland development GO:0030850 14 7 1,000 5,384E-04 9,89E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,384E-04 9,816E-03 ! mRNA stabilization GO:0048255 18 7 1,000 5,384E-04 9,743E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,384E-04 9,672E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 5,384E-04 9,601E-03 ! melanosome organization GO:0032438 10 7 1,000 5,384E-04 9,531E-03 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 5,384E-04 9,463E-03 ! centrosome duplication GO:0051298 14 7 1,000 5,384E-04 9,395E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,384E-04 9,329E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 5,384E-04 9,263E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,384E-04 9,198E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 5,384E-04 9,134E-03 ! peptidyl-histidine modification GO:0018202 17 7 1,000 5,384E-04 9,071E-03 ! axonal fasciculation GO:0007413 19 7 1,000 5,384E-04 9,009E-03 ! melanin biosynthetic process GO:0042438 10 7 1,000 5,384E-04 8,948E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 5,786E-04 9,551E-03 ! peripheral nervous system development GO:0007422 68 32 2,000 5,871E-04 9,627E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 5,871E-04 9,562E-03 ! axon guidance GO:0007411 162 75 3,000 6,088E-04 9,849E-03 ! response to ionizing radiation GO:0010212 74 33 2,000 6,434E-04 0,01034127 ! leukocyte chemotaxis GO:0030595 55 33 2,000 6,434E-04 0,01027368 GO:0060326|cell chemotaxis, ! serine family amino acid metabolic process GO:0009069 56 34 2,000 7,03E-04 0,01115274 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,155E-04 0,01127653 ! male meiosis GO:0007140 9 8 1,000 7,155E-04 0,01120425 ! oligopeptide transport GO:0006857 16 8 1,000 7,155E-04 0,01113288 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,155E-04 0,01106242 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,155E-04 0,01099285 ! pigment granule organization GO:0048753 17 8 1,000 7,155E-04 0,01092414 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,155E-04 0,01085629 ! astrocyte differentiation GO:0048708 19 8 1,000 7,155E-04 0,01078927 ! melanin metabolic process GO:0006582 17 8 1,000 7,155E-04 0,01072308 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,155E-04 0,0106577 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,155E-04 0,01059311 ! Schwann cell differentiation GO:0014037 21 8 1,000 7,155E-04 0,01052929 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,155E-04 0,01046624 ! response to tumor cell GO:0002347 16 8 1,000 7,155E-04 0,01040394 ! blastocyst growth GO:0001832 19 8 1,000 7,155E-04 0,01034238 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 7,155E-04 0,01028154 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,155E-04 0,01022142 ! DNA damage checkpoint GO:0000077 78 35 2,000 7,661E-04 0,01088079 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 7,661E-04 0,0108179 ! placenta development GO:0001890 53 35 2,000 7,661E-04 0,01075572 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 8,137E-04 0,01135939 ! protein import into nucleus GO:0006606 174 82 3,000 8,521E-04 0,01182705 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 8,916E-04 0,01230676 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 3,000 8,916E-04 0,01223762 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 9,026E-04 0,01231927 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 9,026E-04 0,01225083 ! cell proliferation in forebrain GO:0021846 18 9 1,000 9,168E-04 0,01237394 ! cellular copper ion homeostasis GO:0006878 12 9 1,000 9,168E-04 0,01230595 ! cerebral cortex cell migration GO:0021795 18 9 1,000 9,168E-04 0,0122387 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,168E-04 0,01217219 ! regulation of telomere maintenance GO:0032204 17 9 1,000 9,168E-04 0,01210639 ! negative regulation of transport GO:0051051 164 85 3,000 9,747E-04 0,01280212 ! regulation of neuron differentiation GO:0045664 187 85 3,000 9,747E-04 0,01273366 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 9,747E-04 0,01266593 ! DNA integrity checkpoint GO:0031570 82 38 2,000 9,763E-04 0,01262006 ! glycogen metabolic process GO:0005977 63 38 2,000 9,763E-04 0,01255364 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 1,054E-03 0,01347789 ! glucan metabolic process GO:0044042 64 39 2,000 1,054E-03 0,01340769 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 2,000 1,135E-03 0,01436569 ! regulation of action potential in neuron GO:0019228 80 40 2,000 1,135E-03 0,01429164 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 1,142E-03 0,0143086 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,142E-03 0,0142356 ! lung alveolus development GO:0048286 26 10 1,000 1,142E-03 0,01416334 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,142E-03 0,01409181 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,142E-03 0,01402099 GO:0005978|glycogen biosynthetic process, ! multicellular organism growth GO:0035264 19 10 1,000 1,142E-03 0,01395089 ! motor axon guidance GO:0008045 22 10 1,000 1,142E-03 0,01388148 ! copper ion homeostasis GO:0055070 13 10 1,000 1,142E-03 0,01381276 ! regulation of bone resorption GO:0045124 25 10 1,000 1,142E-03 0,01374472 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,142E-03 0,01367734 ! blastocyst formation GO:0001825 18 10 1,000 1,142E-03 0,01361062 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,142E-03 0,01354455 ! protein localization in nucleus GO:0034504 192 89 3,000 1,157E-03 0,01365329 ! ossification GO:0001503 205 91 3,000 1,256E-03 0,01475599 ! bone development GO:0060348 206 92 3,000 1,308E-03 0,0152922 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,309E-03 0,01522619 ! telencephalon cell migration GO:0022029 23 11 1,000 1,391E-03 0,01610778 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,391E-03 0,0160318 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,391E-03 0,01595653 ! blood vessel remodeling GO:0001974 30 11 1,000 1,391E-03 0,01588197 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,391E-03 0,0158081 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,391E-03 0,01573491 ! melanocyte differentiation GO:0030318 20 11 1,000 1,391E-03 0,0156624 GO:0050931|pigment cell differentiation, ! regulation of intracellular pH GO:0051453 21 11 1,000 1,391E-03 0,01559055 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,391E-03 0,01551936 GO:0006809|nitric oxide biosynthetic process, ! apical protein localization GO:0045176 18 11 1,000 1,391E-03 0,01544882 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,391E-03 0,01537892 ! oocyte development GO:0048599 20 11 1,000 1,391E-03 0,01530964 ! energy reserve metabolic process GO:0006112 76 44 2,000 1,499E-03 0,01641823 ! double-strand break repair GO:0006302 85 44 2,000 1,499E-03 0,01634494 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 1,59E-03 0,01726902 ! developmental growth GO:0048589 88 45 2,000 1,6E-03 0,01729252 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,664E-03 0,01790647 ! drug transport GO:0015893 16 12 1,000 1,664E-03 0,01782793 ! tyrosine metabolic process GO:0006570 19 12 1,000 1,664E-03 0,01775008 ! forebrain cell migration GO:0021885 24 12 1,000 1,664E-03 0,01767291 ! histone acetylation GO:0016573 27 12 1,000 1,664E-03 0,0175964 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,664E-03 0,01752056 ! T cell homeostasis GO:0043029 28 12 1,000 1,664E-03 0,01744536 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,664E-03 0,01737081 ! oocyte differentiation GO:0009994 21 12 1,000 1,664E-03 0,01729689 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,664E-03 0,0172236 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,664E-03 0,01715092 ! embryonic placenta development GO:0001892 21 12 1,000 1,664E-03 0,01707886 ! response to cold GO:0009409 17 12 1,000 1,664E-03 0,0170074 ! localization within membrane GO:0051668 26 12 1,000 1,664E-03 0,01693654 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,705E-03 0,01728271 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 1,705E-03 0,01721129 ! leukocyte migration GO:0050900 75 46 2,000 1,705E-03 0,01714047 ! positive regulation of defense response GO:0031349 88 48 2,000 1,928E-03 0,01930454 ! regulation of inflammatory response GO:0050727 84 48 2,000 1,928E-03 0,01922575 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,96E-03 0,01946205 GO:0000725|recombinational repair, ! cartilage condensation GO:0001502 22 13 1,000 1,96E-03 0,01938326 ! asymmetric protein localization GO:0008105 24 13 1,000 1,96E-03 0,0193051 ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 1,96E-03 0,01922757 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,96E-03 0,01915066 ! regulation of action potential GO:0001508 102 50 2,000 2,169E-03 0,02110737 ! activation of caspase activity GO:0006919 95 50 2,000 2,169E-03 0,02102361 ! regulation of S phase GO:0033261 26 14 1,000 2,279E-03 0,02200329 ! bone mineralization GO:0030282 18 14 1,000 2,279E-03 0,02191667 ! regulation of cellular pH GO:0030641 27 14 1,000 2,279E-03 0,02183072 ! regulation of RNA stability GO:0043487 33 14 1,000 2,279E-03 0,02174544 ! response to temperature stimulus GO:0009266 84 51 2,000 2,296E-03 0,02182119 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 2,427E-03 0,02298128 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 2,427E-03 0,02289255 ! positive regulation of growth GO:0045927 96 53 2,000 2,563E-03 0,02408252 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,62E-03 0,02452754 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,62E-03 0,02443392 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,62E-03 0,02434102 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,62E-03 0,02424882 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,62E-03 0,02415731 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,62E-03 0,02406649 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,62E-03 0,02397636 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,62E-03 0,02388689 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,704E-03 0,02455401 ! regulation of cell shape GO:0008360 142 54 2,000 2,704E-03 0,02446307 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 2,849E-03 0,02568272 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 2,985E-03 0,02680751 ! pituitary gland development GO:0021983 30 16 1,000 2,985E-03 0,02670931 ! response to osmotic stress GO:0006970 27 16 1,000 2,985E-03 0,02661183 ! DNA replication initiation GO:0006270 28 16 1,000 2,985E-03 0,02651506 ! neuron recognition GO:0008038 40 16 1,000 2,985E-03 0,02641899 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,985E-03 0,02632362 ! biomineral formation GO:0031214 22 16 1,000 2,985E-03 0,02622893 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 2,985E-03 0,02613492 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,985E-03 0,02604158 ! regulation of protein catabolic process GO:0042176 126 56 2,000 2,999E-03 0,02607311 ! regulation of DNA replication GO:0006275 105 56 2,000 2,999E-03 0,02598065 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 3,154E-03 0,02722518 ! regulation of bone remodeling GO:0046850 143 57 2,000 3,154E-03 0,02712932 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,154E-03 0,02703413 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 2,000 3,154E-03 0,02693961 ! regulation of intracellular transport GO:0032386 108 57 2,000 3,154E-03 0,02684574 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,313E-03 0,02810655 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 3,313E-03 0,0280093 ! aging GO:0007568 112 58 2,000 3,313E-03 0,02791271 ! regulation of tissue remodeling GO:0034103 146 58 2,000 3,313E-03 0,02781679 ! glial cell development GO:0021782 28 17 1,000 3,371E-03 0,02820588 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,371E-03 0,02810962 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 3,371E-03 0,02801401 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 3,371E-03 0,02791905 ! limbic system development GO:0021761 40 18 1,000 3,78E-03 0,03119777 ! patterning of blood vessels GO:0001569 43 18 1,000 3,78E-03 0,03109273 ! centrosome cycle GO:0007098 26 18 1,000 3,78E-03 0,03098839 ! positive regulation of proteolysis GO:0045862 36 18 1,000 3,78E-03 0,03088475 ! neural crest cell migration GO:0001755 41 18 1,000 3,78E-03 0,0307818 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 3,78E-03 0,03067953 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 3,78E-03 0,03057795 ! regulation of heart contraction GO:0008016 123 61 2,000 3,822E-03 0,03081303 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 3,822E-03 0,03071167 ! regulation of homeostatic process GO:0032844 148 62 2,000 4,001E-03 0,03204763 ! skeletal system morphogenesis GO:0048705 118 63 2,000 4,185E-03 0,03341513 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,211E-03 0,03350598 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,211E-03 0,03339719 ! cerebral cortex development GO:0021987 40 19 1,000 4,211E-03 0,03328911 ! pigmentation during development GO:0048066 42 19 1,000 4,211E-03 0,03318173 ! neuromuscular junction development GO:0007528 43 19 1,000 4,211E-03 0,03307503 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,211E-03 0,03296902 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,57E-03 0,03566582 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,663E-03 0,03627687 ! protein amino acid acetylation GO:0006473 41 20 1,000 4,663E-03 0,03616171 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 4,663E-03 0,03604727 ! response to alkaloid GO:0043279 38 20 1,000 4,663E-03 0,03593356 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,663E-03 0,03582056 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 4,769E-03 0,03652497 ! lipid phosphorylation GO:0046834 43 21 1,000 5,136E-03 0,03921184 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 5,136E-03 0,03908968 ! diencephalon development GO:0021536 36 21 1,000 5,136E-03 0,03896828 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 5,136E-03 0,03884764 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 5,136E-03 0,03872774 ! negative regulation of cell size GO:0045792 144 69 2,000 5,4E-03 0,0405917 ! lung development GO:0030324 165 69 2,000 5,4E-03 0,04046719 ! developmental maturation GO:0021700 128 69 2,000 5,4E-03 0,04034343 ! germ cell development GO:0007281 133 70 2,000 5,621E-03 0,04186512 ! cellular response to starvation GO:0009267 37 22 1,000 5,631E-03 0,04181253 ! apoptotic nuclear changes GO:0030262 34 22 1,000 5,631E-03 0,04168583 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 5,631E-03 0,04155989 ! cell cycle checkpoint GO:0000075 145 71 2,000 5,847E-03 0,04302493 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 5,847E-03 0,04289573 ! respiratory tube development GO:0030323 171 72 2,000 6,079E-03 0,04446091 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 6,147E-03 0,04482386 ! regulation of caspase activity GO:0043281 136 74 2,000 6,558E-03 0,04768164 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 6,558E-03 0,04754015 ! respiratory system development GO:0060541 175 74 2,000 6,558E-03 0,0473995 ! organelle localization GO:0051640 155 74 2,000 6,558E-03 0,04725968 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 6,683E-03 0,04801838 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 6,683E-03 0,04787756 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 6,683E-03 0,04773757 ! pallium development GO:0021543 56 24 1,000 6,683E-03 0,04759839 ! oogenesis GO:0048477 44 24 1,000 6,683E-03 0,04746002 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 6,683E-03 0,04732246 ! reproductive structure development GO:0048608 131 75 2,000 6,806E-03 0,04805377 ! leukocyte homeostasis GO:0001776 50 25 1,000 7,24E-03 0,05096986 ! protein tetramerization GO:0051262 57 25 1,000 7,24E-03 0,05082339 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 7,318E-03 0,05122686 ! regulation of catabolic process GO:0009894 173 77 2,000 7,318E-03 0,0510805 ! molting cycle process GO:0022404 52 26 1,000 7,817E-03 0,05440551 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 1,000 7,817E-03 0,05425094 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 1,000 7,817E-03 0,05409726 GO:0051297|centrosome organization, ! neural crest cell development GO:0014032 59 26 1,000 7,817E-03 0,05394444 GO:0014033|neural crest cell differentiation, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 7,817E-03 0,05379249 ! protein oligomerization GO:0051259 149 79 2,000 7,853E-03 0,05388793 ! response to hypoxia GO:0001666 178 81 2,000 8,41E-03 0,05754878 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 8,414E-03 0,05741644 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 8,414E-03 0,0572565 ! mitochondrial membrane organization GO:0007006 60 27 1,000 8,414E-03 0,05709746 ! response to starvation GO:0042594 47 27 1,000 8,414E-03 0,05693929 ! response to toxin GO:0009636 49 27 1,000 8,414E-03 0,056782 ! regulation of chromosome organization GO:0033044 49 27 1,000 8,414E-03 0,05662558 ! cellular response to nutrient levels GO:0031669 45 27 1,000 8,414E-03 0,05647001 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 8,414E-03 0,0563153 ! regulation of peptidase activity GO:0052547 150 82 2,000 8,697E-03 0,05804933 ! response to drug GO:0042493 149 83 2,000 8,989E-03 0,0598395 ! response to oxygen levels GO:0070482 183 83 2,000 8,989E-03 0,05967689 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 9,031E-03 0,05978934 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 9,031E-03 0,05962775 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 9,031E-03 0,05946703 ! protein amino acid acylation GO:0043543 59 28 1,000 9,031E-03 0,05930717 ! dendrite development GO:0016358 67 28 1,000 9,031E-03 0,05914817 ! base-excision repair GO:0006284 41 28 1,000 9,031E-03 0,05899002 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 9,667E-03 0,06297959 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 9,667E-03 0,06281209 ! response to organic cyclic substance GO:0014070 58 29 1,000 9,667E-03 0,06264548 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 9,667E-03 0,06247976 ! somitogenesis GO:0001756 52 29 1,000 9,667E-03 0,0623149 ! regulation of protein transport GO:0051223 165 87 2,000 0,0102175 0,06568779 GO:0070201|regulation of establishment of protein localization, ! tissue homeostasis GO:0001894 50 30 1,000 0,01032329 0,06619371 GO:0048871|multicellular organismal homeostasis, ! amine biosynthetic process GO:0009309 146 88 2,000 0,01053897 0,06739975 ! peptide transport GO:0015833 60 31 1,000 0,01099841 0,07015435 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01099841 0,06997166 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01099841 0,06978991 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01099841 0,06960911 ! response to heat GO:0009408 54 31 1,000 0,01099841 0,06942924 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01119937 0,07051561 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,0116925 0,07343128 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,0116925 0,07324299 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01223389 0,07643832 ! regulation of pH GO:0006885 56 33 1,000 0,01240534 0,07731185 ! pigment biosynthetic process GO:0046148 73 33 1,000 0,01240534 0,07711513 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01240534 0,0769194 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01240534 0,07672467 ! regulation of membrane potential GO:0042391 179 94 2,000 0,0125905 0,07767322 ! regulation of defense response GO:0031347 171 95 2,000 0,01295303 0,07970845 ! glial cell differentiation GO:0010001 67 34 1,000 0,01313673 0,08063578 ! sex differentiation GO:0007548 171 96 2,000 0,01332149 0,08156488 ! telencephalon development GO:0021537 81 35 1,000 0,01388647 0,08481162 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01388647 0,08460012 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01407622 0,08554283 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01465435 0,08883516 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01465435 0,08861527 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01485482 0,08960572 GO:0060538|skeletal muscle organ development, ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01544016 0,09290716 ! tissue remodeling GO:0048771 78 37 1,000 0,01544016 0,09267889 ! female gonad development GO:0008585 71 37 1,000 0,01544016 0,09245174 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01544016 0,09222569 ! pigment metabolic process GO:0042440 87 38 1,000 0,0162437 0,09678871 ! learning GO:0007612 82 40 1,000 0,0179032 0,10641731 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,0179032 0,10615901 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,0179032 0,10590197 ! gliogenesis GO:0042063 91 41 1,000 0,01875875 0,11069476 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01875875 0,11042802 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01875875 0,11016257 ! ear morphogenesis GO:0042471 64 42 1,000 0,01963125 0,11500992 ! T cell differentiation GO:0030217 93 42 1,000 0,01963125 0,11473477 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01963125 0,11446094 ! cytokinesis GO:0000910 84 42 1,000 0,01963125 0,11418842 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,01963125 0,11391719 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02052049 0,11879516 GO:0090047|positive regulation of transcription regulator activity, ! glucose transport GO:0015758 66 43 1,000 0,02052049 0,11851432 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02052049 0,11823481 ! segmentation GO:0035282 78 43 1,000 0,02052049 0,11795661 ! hexose transport GO:0008645 68 44 1,000 0,02142629 0,12287425 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,02142629 0,12258649 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02234846 0,12756374 ! biopolymer methylation GO:0043414 91 45 1,000 0,02234846 0,12726639 ! B cell differentiation GO:0030183 124 45 1,000 0,02234846 0,12697042 ! female gamete generation GO:0007292 71 45 1,000 0,02234846 0,12667583 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,0232868 0,13168901 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,0232868 0,13138488 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,0232868 0,13108215 ! cell growth GO:0016049 90 46 1,000 0,0232868 0,13078081 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,0232868 0,13048085 ! mitochondrial transport GO:0006839 94 48 1,000 0,02521126 0,14094077 ! cellular component disassembly GO:0022411 89 48 1,000 0,02521126 0,14061899 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02521126 0,14029867 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02521126 0,13997981 ! methylation GO:0032259 97 48 1,000 0,02521126 0,13966239 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02534263 0,14007253 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02534263 0,13975634 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02534263 0,13944157 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02534263 0,13912822 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02534263 0,13881627 ! neuron fate determination GO:0048664 7 5 0,000 0,02534263 0,13850572 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02534263 0,13819656 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02534263 0,13788877 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02534263 0,13758235 ! polyol transport GO:0015791 12 5 0,000 0,02534263 0,13727729 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02534263 0,13697358 ! response to superoxide GO:0000303 10 5 0,000 0,02534263 0,13667121 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02534263 0,13637017 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02534263 0,13607045 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02534263 0,13577205 ! female meiosis GO:0007143 10 5 0,000 0,02534263 0,13547496 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02534263 0,13517916 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02534263 0,13488466 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02534263 0,13459143 ! cobalt ion transport GO:0006824 11 5 0,000 0,02534263 0,13429947 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02534263 0,13400878 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02534263 0,13371934 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02534263 0,13343116 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02534263 0,13314421 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02534263 0,13285849 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02534263 0,132574 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02534263 0,13229072 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02534263 0,13200865 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02534263 0,13172778 ! transposition GO:0032196 9 5 0,000 0,02534263 0,1314481 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02534263 0,13116961 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02534263 0,1308923 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02534263 0,13061615 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02534263 0,13034117 ! behavioral response to pain GO:0048266 10 5 0,000 0,02534263 0,13006735 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02534263 0,12979467 ! Notch receptor processing GO:0007220 11 5 0,000 0,02534263 0,12952313 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02534263 0,12925273 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02534263 0,12898345 ! micturition GO:0060073 9 5 0,000 0,02534263 0,12871529 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02534263 0,12844825 ! copulation GO:0007620 9 5 0,000 0,02534263 0,12818231 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02534263 0,12791747 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02534263 0,12765373 ! bioluminescence GO:0008218 9 5 0,000 0,02534263 0,12739106 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02534263 0,12712948 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02534263 0,12686897 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02534263 0,12660952 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02534263 0,12635114 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02534263 0,1260938 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02534263 0,12583751 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02534263 0,12558227 ! grooming behavior GO:0007625 6 5 0,000 0,02534263 0,12532805 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02534263 0,12507486 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02534263 0,12482269 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02534263 0,12457154 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02534263 0,1243214 ! response to protozoan GO:0001562 13 5 0,000 0,02534263 0,12407226 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02534263 0,12382411 ! lymph vessel development GO:0001945 10 5 0,000 0,02534263 0,12357696 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02534263 0,12333079 ! endochondral ossification GO:0001958 17 5 0,000 0,02534263 0,1230856 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02534263 0,12284138 ! single strand break repair GO:0000012 8 5 0,000 0,02534263 0,12259813 ! parathyroid gland development GO:0060017 14 5 0,000 0,02534263 0,12235584 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02534263 0,12211451 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02534263 0,12187413 ! cytokine secretion GO:0050663 15 5 0,000 0,02534263 0,12163469 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02534263 0,12139619 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02534263 0,12115862 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02534263 0,12092199 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02534263 0,12068627 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02534263 0,12045147 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02534263 0,12021759 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02534263 0,11998461 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02534263 0,11975253 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02534263 0,11952135 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02534263 0,11929105 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02534263 0,11906165 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02534263 0,11883312 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02534263 0,11860547 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02534263 0,11837869 ! valine metabolic process GO:0006573 12 5 0,000 0,02534263 0,11815278 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02534263 0,11792773 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02534263 0,11770353 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02534263 0,11748018 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02534263 0,11725768 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02534263 0,11703602 ! polyol catabolic process GO:0046174 9 5 0,000 0,02534263 0,1168152 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02534263 0,11659521 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02534263 0,11637605 ! muscle cell migration GO:0014812 8 5 0,000 0,02534263 0,1161577 ! mitochondrial fission GO:0000266 8 5 0,000 0,02534263 0,11594018 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02534263 0,11572347 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02534263 0,11550757 ! mRNA transcription GO:0009299 10 5 0,000 0,02534263 0,11529247 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02534263 0,11507817 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02534263 0,11486467 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02534263 0,11465196 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02534263 0,11444003 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02534263 0,11422889 ! monocyte activation GO:0042117 10 5 0,000 0,02534263 0,11401852 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02534263 0,11380893 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02534263 0,1136001 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02534263 0,11339205 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02534263 0,11318475 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02534263 0,11297821 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02534263 0,11277242 ! forebrain neuron development GO:0021884 13 5 0,000 0,02534263 0,11256738 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02534263 0,11236308 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02534263 0,11215952 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02534263 0,1119567 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02534263 0,11175462 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02534263 0,11155326 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02534263 0,11135262 ! lipid glycosylation GO:0030259 7 5 0,000 0,02534263 0,11115271 ! nucleobase transport GO:0015851 6 5 0,000 0,02534263 0,11095351 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02534263 0,11075502 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02534263 0,11055724 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02534263 0,11036017 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02534263 0,1101638 ! basic amino acid transport GO:0015802 12 5 0,000 0,02534263 0,10996813 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02534263 0,10977315 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02534263 0,10957886 ! actin nucleation GO:0045010 11 5 0,000 0,02534263 0,10938526 ! depurination GO:0045007 5 5 0,000 0,02534263 0,10919234 ! depyrimidination GO:0045008 10 5 0,000 0,02534263 0,1090001 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02534263 0,10880854 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02534263 0,10861764 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02534263 0,10842742 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02534263 0,10823786 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02534263 0,10804896 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02534263 0,10786073 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02534263 0,10767314 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02534263 0,10748621 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02534263 0,10729992 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02534263 0,10711428 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02534263 0,10692929 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02534263 0,10674493 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02534263 0,1065612 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02534263 0,1063781 ! response to arsenic GO:0046685 11 5 0,000 0,02534263 0,10619564 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02534263 0,1060138 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02534263 0,10583258 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02534263 0,10565197 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02534263 0,10547199 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02534263 0,10529261 ! response to mercury ion GO:0046689 8 5 0,000 0,02534263 0,10511385 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02534263 0,10493569 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02534263 0,10475813 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02534263 0,10458118 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02534263 0,10440482 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02534263 0,10422905 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02534263 0,10405388 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02534263 0,10387929 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02534263 0,10370529 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02534263 0,10353187 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02534263 0,10335903 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02534263 0,10318676 ! embryonic cleavage GO:0040016 6 5 0,000 0,02534263 0,10301507 ! peroxisome fission GO:0016559 5 5 0,000 0,02534263 0,10284395 ! histone demethylation GO:0016577 13 5 0,000 0,02534263 0,10267339 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02534263 0,10250341 ! mitotic recombination GO:0006312 9 5 0,000 0,02534263 0,10233398 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02534263 0,10216511 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02534263 0,1019968 ! metaphase plate congression GO:0051310 7 5 0,000 0,02534263 0,10182904 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02534263 0,10166183 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02534263 0,10149517 ! enteric nervous system development GO:0048484 8 5 0,000 0,02534263 0,10132906 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02534263 0,10116349 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02534263 0,10099846 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02534263 0,10083397 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02534263 0,10067001 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02534263 0,10050659 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02534263 0,10034369 ! B cell homeostasis GO:0001782 13 5 0,000 0,02534263 0,10018132 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02534263 0,10001948 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02534263 0,09985816 ! metaphase GO:0051323 11 5 0,000 0,02534263 0,09969735 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02534263 0,09953707 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02534263 0,0993773 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02534263 0,09921804 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02534263 0,09905929 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02534263 0,09890105 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02534263 0,09874331 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02534263 0,09858608 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02534263 0,09842934 ! response to redox state GO:0051775 6 5 0,000 0,02534263 0,09827311 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02534263 0,09811736 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02534263 0,09796212 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02534263 0,09780736 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02534263 0,09765309 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02534263 0,0974993 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02534263 0,097346 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02534263 0,09719318 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02534263 0,09704084 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02534263 0,09688898 ! striatum development GO:0021756 14 5 0,000 0,02534263 0,09673759 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02534263 0,09658667 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02534263 0,09643623 ! glial cell migration GO:0008347 10 5 0,000 0,02534263 0,09628625 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02534263 0,09613673 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02534263 0,09598768 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02534263 0,0958391 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02534263 0,09569097 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02534263 0,0955433 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02534263 0,09539608 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02534263 0,09524932 ! neuroprotection GO:0043526 8 5 0,000 0,02534263 0,09510301 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02534263 0,09495714 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02534263 0,09481173 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02534263 0,09466675 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02534263 0,09452222 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02534263 0,09437814 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02534263 0,09423449 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02534263 0,09409127 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02534263 0,09394849 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02534263 0,09380615 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02534263 0,09366423 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02534263 0,09352274 ! spindle assembly GO:0051225 6 5 0,000 0,02534263 0,09338168 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02534263 0,09324105 ! protein palmitoylation GO:0018345 12 5 0,000 0,02534263 0,09310084 ! drug metabolic process GO:0017144 7 5 0,000 0,02534263 0,09296105 ! stem cell division GO:0017145 11 5 0,000 0,02534263 0,09282167 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02534263 0,09268272 ! organ regeneration GO:0031100 7 5 0,000 0,02534263 0,09254418 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02534263 0,09240605 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02534263 0,09226834 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02619701 0,09523706 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02619701 0,09509555 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,02619701 0,09495445 ! protein homooligomerization GO:0051260 84 49 1,000 0,02619701 0,09481378 ! endocrine system development GO:0035270 109 50 1,000 0,0271982 0,0982917 ! regulation of ossification GO:0030278 123 50 1,000 0,0271982 0,09814652 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02821463 0,10166422 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02821463 0,10151449 ! positive regulation of binding GO:0051099 88 52 1,000 0,02924613 0,10507104 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,02924613 0,10491675 ! histone modification GO:0016570 104 52 1,000 0,02924613 0,10476291 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,02924613 0,10460953 ! vesicle organization GO:0016050 127 53 1,000 0,03029253 0,10819394 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,03029253 0,10803599 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,03029253 0,1078785 ! synapse organization GO:0050808 102 53 1,000 0,03029253 0,10772148 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03033399 0,10771211 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03033399 0,10755577 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03033399 0,1073999 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03033399 0,10724447 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03033399 0,10708949 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03033399 0,10693496 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03033399 0,10678088 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03033399 0,10662724 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03033399 0,10647404 ! response to oxygen radical GO:0000305 11 6 0,000 0,03033399 0,10632127 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03033399 0,10616895 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03033399 0,10601706 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03033399 0,10586561 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03033399 0,10571459 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03033399 0,105564 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03033399 0,10541384 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03033399 0,1052641 ! forebrain regionalization GO:0021871 9 6 0,000 0,03033399 0,10511479 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03033399 0,1049659 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03033399 0,10481744 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03033399 0,10466939 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03033399 0,10452176 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03033399 0,10437455 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03033399 0,10422775 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03033399 0,10408136 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03033399 0,10393538 ! malate metabolic process GO:0006108 13 6 0,000 0,03033399 0,10378982 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03033399 0,10364466 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03033399 0,1034999 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03033399 0,10335555 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03033399 0,1032116 ! protein refolding GO:0042026 15 6 0,000 0,03033399 0,10306805 ! opsonization GO:0008228 8 6 0,000 0,03033399 0,1029249 ! mating behavior GO:0007617 7 6 0,000 0,03033399 0,10278215 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03033399 0,10263979 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03033399 0,10249783 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03033399 0,10235625 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03033399 0,10221507 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03033399 0,10207428 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03033399 0,10193388 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03033399 0,10179386 ! toxin metabolic process GO:0009404 11 6 0,000 0,03033399 0,10165422 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03033399 0,10151497 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03033399 0,1013761 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03033399 0,10123761 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03033399 0,10109949 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03033399 0,10096176 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03033399 0,10082439 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03033399 0,1006874 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03033399 0,10055078 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03033399 0,10041454 ! thymic T cell selection GO:0045061 16 6 0,000 0,03033399 0,10027866 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03033399 0,10014315 ! protein lipoylation GO:0009249 10 6 0,000 0,03033399 0,100008 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03033399 0,09987322 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03033399 0,0997388 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03033399 0,09960474 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03033399 0,09947104 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03033399 0,09933771 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03033399 0,09920472 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03033399 0,0990721 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03033399 0,09893982 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03033399 0,0988079 ! hyperosmotic response GO:0006972 10 6 0,000 0,03033399 0,09867634 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03033399 0,09854512 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03033399 0,09841425 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03033399 0,09828372 ! urea metabolic process GO:0019627 7 6 0,000 0,03033399 0,09815355 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03033399 0,09802371 ! neutrophil activation GO:0042119 7 6 0,000 0,03033399 0,09789423 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03033399 0,09776508 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03033399 0,09763627 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03033399 0,0975078 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03033399 0,09737967 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03033399 0,09725187 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03033399 0,09712441 ! neuron apoptosis GO:0051402 15 6 0,000 0,03033399 0,09699729 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03033399 0,09687049 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03033399 0,09674403 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03033399 0,0966179 ! carnitine transport GO:0015879 10 6 0,000 0,03033399 0,09649209 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03033399 0,09636662 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03033399 0,09624147 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03033399 0,09611664 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03033399 0,09599214 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03033399 0,09586795 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03033399 0,09574409 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03033399 0,09562055 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03033399 0,09549733 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03033399 0,09537443 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03033399 0,09525184 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03033399 0,09512956 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03033399 0,0950076 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03033399 0,09488595 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03033399 0,09476461 ! interaction with symbiont GO:0051702 14 6 0,000 0,03033399 0,09464359 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03033399 0,09452287 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03033399 0,09440246 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03033399 0,09428235 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03033399 0,09416255 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03033399 0,09404306 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03033399 0,09392386 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03033399 0,09380497 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03033399 0,09368638 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03033399 0,09356809 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03033399 0,0934501 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03033399 0,0933324 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03033399 0,093215 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03033399 0,0930979 ! response to pheromone GO:0019236 6 6 0,000 0,03033399 0,09298109 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03033399 0,09286457 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03033399 0,09274835 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03033399 0,09263241 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03033399 0,09251676 ! subpallium development GO:0021544 15 6 0,000 0,03033399 0,09240141 ! neural tube patterning GO:0021532 8 6 0,000 0,03033399 0,09228634 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03033399 0,09217155 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03033399 0,09205705 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03033399 0,09194284 ! G2 phase GO:0051319 16 6 0,000 0,03033399 0,09182891 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03033399 0,09171526 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03033399 0,09160189 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03033399 0,0914888 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03033399 0,09137599 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03033399 0,09126346 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03033399 0,0911512 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03033399 0,09103922 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03033399 0,09092752 ! receptor internalization GO:0031623 11 6 0,000 0,03033399 0,09081609 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03033399 0,09070493 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03033399 0,09059404 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03033399 0,09048343 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03033399 0,09037308 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03033399 0,09026301 ! protein deubiquitination GO:0016579 16 6 0,000 0,03033399 0,0901532 ! protein destabilization GO:0031648 9 6 0,000 0,03033399 0,09004366 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03033399 0,08993438 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03033399 0,08982537 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03033399 0,08971662 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03033399 0,08960814 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03033399 0,08949991 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03033399 0,08939195 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03033399 0,08928425 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03033399 0,08917681 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03033399 0,08906963 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03033399 0,0889627 ! neural plate development GO:0001840 9 6 0,000 0,03033399 0,08885603 ! catecholamine transport GO:0051937 9 6 0,000 0,03033399 0,08874961 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03033399 0,08864346 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03033399 0,08853755 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03033399 0,0884319 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03033399 0,08832649 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03033399 0,08822134 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03033399 0,08811644 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03033399 0,08801179 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03033399 0,08790739 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03033399 0,08780323 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03033399 0,08769932 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03033399 0,08759566 GO:0055081|anion homeostasis, ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03135364 0,09043323 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03135364 0,09032659 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,03135364 0,0902202 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03242929 0,0932056 ! cell recognition GO:0008037 98 55 1,000 0,03242929 0,09309607 ! cell maturation GO:0048469 107 55 1,000 0,03242929 0,0929868 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03242929 0,09287779 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,0335193 0,09588718 ! muscle fiber development GO:0048747 131 57 1,000 0,0346235 0,09893007 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0346235 0,0988145 ! tRNA transcription GO:0009304 17 7 0,000 0,03529992 0,10062742 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03529992 0,10051013 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03529992 0,10039313 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03529992 0,10027639 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03529992 0,10015992 ! sleep GO:0030431 16 7 0,000 0,03529992 0,10004373 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03529992 0,0999278 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03529992 0,09981215 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03529992 0,09969676 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03529992 0,09958163 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03529992 0,09946678 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03529992 0,09935218 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03529992 0,09923785 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03529992 0,09912379 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03529992 0,09900998 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03529992 0,09889644 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03529992 0,09878316 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03529992 0,09867013 ! glycolipid transport GO:0046836 11 7 0,000 0,03529992 0,09855737 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03529992 0,09844486 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03529992 0,09833261 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03529992 0,09822061 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03529992 0,09810887 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03529992 0,09799738 ! pericardium development GO:0060039 16 7 0,000 0,03529992 0,09788615 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03529992 0,09777516 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03529992 0,09766443 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03529992 0,09755395 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03529992 0,09744372 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03529992 0,09733374 ! lipoprotein transport GO:0042953 14 7 0,000 0,03529992 0,09722401 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03529992 0,09711452 ! rhythmic behavior GO:0007622 17 7 0,000 0,03529992 0,09700528 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03529992 0,09689629 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03529992 0,09678754 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03529992 0,09667903 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03529992 0,09657077 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03529992 0,09646275 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03529992 0,09635497 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03529992 0,09624743 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03529992 0,09614013 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03529992 0,09603307 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03529992 0,09592625 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03529992 0,09581966 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03529992 0,09571331 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03529992 0,0956072 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03529992 0,09550132 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03529992 0,09539568 ! spinal cord patterning GO:0021511 14 7 0,000 0,03529992 0,09529027 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03529992 0,09518509 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03529992 0,09508015 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03529992 0,09497544 ! adrenal gland development GO:0030325 17 7 0,000 0,03529992 0,09487095 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03529992 0,0947667 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03529992 0,09466267 ! ovulation GO:0030728 10 7 0,000 0,03529992 0,09455888 ! adenohypophysis development GO:0021984 11 7 0,000 0,03529992 0,09445531 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03529992 0,09435196 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03529992 0,09424885 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03529992 0,09414596 ! microtubule nucleation GO:0007020 21 7 0,000 0,03529992 0,09404329 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03529992 0,09394084 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03529992 0,09383862 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03529992 0,09373662 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03529992 0,09363485 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03529992 0,09353329 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03529992 0,09343196 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03529992 0,09333084 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03529992 0,09322994 ! galactose metabolic process GO:0006012 13 7 0,000 0,03529992 0,09312926 ! vesicle fusion GO:0006906 20 7 0,000 0,03529992 0,0930288 ! response to dietary excess GO:0002021 8 7 0,000 0,03529992 0,09292855 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03529992 0,09282852 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03529992 0,0927287 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03529992 0,0926291 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 0,000 0,03529992 0,09252972 ! nucleoside transport GO:0015858 11 7 0,000 0,03529992 0,09243054 ! nucleoside salvage GO:0043174 11 7 0,000 0,03529992 0,09233158 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03529992 0,09223283 ! male sex determination GO:0030238 15 7 0,000 0,03529992 0,09213429 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03529992 0,09203596 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03529992 0,09193784 ! parturition GO:0007567 16 7 0,000 0,03529992 0,09183993 ! rRNA modification GO:0000154 14 7 0,000 0,03529992 0,09174223 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03529992 0,09164473 ! spindle checkpoint GO:0031577 16 7 0,000 0,03529992 0,09154745 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03529992 0,09145037 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03529992 0,09135349 ! monocyte differentiation GO:0030224 16 7 0,000 0,03529992 0,09125682 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03529992 0,09116035 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03529992 0,09106409 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03529992 0,09096803 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03529992 0,09087218 ! fibrinolysis GO:0042730 11 7 0,000 0,03529992 0,09077652 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03529992 0,09068107 ! eating behavior GO:0042755 8 7 0,000 0,03529992 0,09058581 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03529992 0,09049076 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03529992 0,09039591 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03529992 0,09030125 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03529992 0,09020679 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03529992 0,09011253 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03529992 0,09001847 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03529992 0,0899246 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03529992 0,08983093 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03529992 0,08973746 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03529992 0,08964417 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03529992 0,08955109 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03529992 0,08945819 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03529992 0,08936549 ! histone ubiquitination GO:0016574 9 7 0,000 0,03529992 0,08927298 ! regulation of meiosis GO:0040020 12 7 0,000 0,03529992 0,08918066 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03529992 0,08908853 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03529992 0,08899659 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03529992 0,08890484 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03529992 0,08881328 ! transcription termination GO:0006353 14 7 0,000 0,03529992 0,08872191 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03529992 0,08863072 ! anaphase GO:0051322 18 7 0,000 0,03529992 0,08853973 GO:0000090|mitotic anaphase, ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03529992 0,08844892 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03529992 0,08835829 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03529992 0,08826786 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03529992 0,0881776 ! diuresis GO:0030146 12 7 0,000 0,03529992 0,08808753 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03529992 0,08799765 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03529992 0,08790795 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03529992 0,08781843 ! antibiotic transport GO:0042891 9 7 0,000 0,03529992 0,08772909 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03529992 0,08763993 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03529992 0,08755096 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03529992 0,08746217 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03529992 0,08737355 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03529992 0,08728512 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03529992 0,08719686 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03529992 0,08710878 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03529992 0,08702088 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03529992 0,08693316 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03529992 0,08684561 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03529992 0,08675824 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03529992 0,08667105 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03529992 0,08658403 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03529992 0,08649719 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03529992 0,08641052 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03529992 0,08632402 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03529992 0,08623769 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03529992 0,08615154 ! muscle adaptation GO:0043500 13 7 0,000 0,03529992 0,08606556 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03529992 0,08597976 ! retina homeostasis GO:0001895 12 7 0,000 0,03529992 0,08589412 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03529992 0,08580865 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03529992 0,08572335 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03529992 0,08563823 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03529992 0,08555327 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03574172 0,08653818 ! lipid modification GO:0030258 112 60 1,000 0,03801952 0,09196207 ! DNA catabolic process GO:0006308 94 60 1,000 0,03801952 0,09187111 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04024055 0,09714197 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04024055 0,09704607 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04024055 0,09695037 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04024055 0,09685485 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04024055 0,09675952 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04024055 0,09666438 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04024055 0,09656942 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04024055 0,09647465 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04024055 0,09638007 ! meiotic prophase I GO:0007128 14 8 0,000 0,04024055 0,09628567 ! response to zinc ion GO:0010043 12 8 0,000 0,04024055 0,09619146 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04024055 0,09609743 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04024055 0,09600359 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04024055 0,09590992 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04024055 0,09581644 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04024055 0,09572315 ! signal peptide processing GO:0006465 12 8 0,000 0,04024055 0,09563003 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04024055 0,0955371 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04024055 0,09544434 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04024055 0,09535177 ! succinate metabolic process GO:0006105 17 8 0,000 0,04024055 0,09525937 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04024055 0,09516715 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04024055 0,09507512 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04024055 0,09498326 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04024055 0,09489157 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04024055 0,09480007 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04024055 0,09470874 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04024055 0,09461759 ! reflex GO:0060004 17 8 0,000 0,04024055 0,09452661 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04024055 0,0944358 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04024055 0,09434517 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04024055 0,09425472 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04024055 0,09416444 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04024055 0,09407433 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04024055 0,09398439 ! histidine catabolic process GO:0006548 10 8 0,000 0,04024055 0,09389462 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04024055 0,09380503 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04024055 0,09371561 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04024055 0,09362635 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04024055 0,09353727 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04024055 0,09344836 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04024055 0,09335961 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04024055 0,09327104 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04024055 0,09318263 ! macrophage activation GO:0042116 13 8 0,000 0,04024055 0,09309439 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04024055 0,09300631 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04024055 0,0929184 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04024055 0,09283066 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04024055 0,09274309 ! purine salvage GO:0043101 12 8 0,000 0,04024055 0,09265567 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04024055 0,09256843 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04024055 0,09248135 ! osteoblast development GO:0002076 17 8 0,000 0,04024055 0,09239443 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04024055 0,09230767 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04024055 0,09222108 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04024055 0,09213465 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04024055 0,09204838 ! response to UV-B GO:0010224 17 8 0,000 0,04024055 0,09196227 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04024055 0,09187633 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04024055 0,09179054 ! intermediate filament organization GO:0045109 12 8 0,000 0,04024055 0,09170492 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04024055 0,09161945 ! cellular extravasation GO:0045123 13 8 0,000 0,04024055 0,09153414 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04024055 0,091449 ! response to antibiotic GO:0046677 11 8 0,000 0,04024055 0,09136401 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04024055 0,09127917 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04024055 0,0911945 ! DNA topological change GO:0006265 12 8 0,000 0,04024055 0,09110998 ! response to tropane GO:0014073 15 8 0,000 0,04024055 0,09102562 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04024055 0,09094142 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04024055 0,09085737 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04024055 0,09077347 ! mast cell activation GO:0045576 14 8 0,000 0,04024055 0,09068973 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04024055 0,09060615 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04024055 0,09052272 ! gas homeostasis GO:0033483 14 8 0,000 0,04024055 0,09043944 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04024055 0,09035632 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04024055 0,09027334 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04024055 0,09019052 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04024055 0,09010786 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04024055 0,09002534 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04024055 0,08994297 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04024055 0,08986076 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04024055 0,0897787 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04024055 0,08969678 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04024055 0,08961501 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04024055 0,0895334 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04024055 0,08945193 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04024055 0,08937061 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04024055 0,08928944 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04024055 0,08920841 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04024055 0,08912753 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04024055 0,0890468 ! hormone catabolic process GO:0042447 17 8 0,000 0,04024055 0,08896622 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04024055 0,08888578 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04024055 0,08880548 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04024055 0,08872533 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04024055 0,08864533 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04024055 0,08856547 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04024055 0,08848575 ! adult feeding behavior GO:0008343 10 8 0,000 0,04024055 0,08840618 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04024055 0,08832675 ! ATP catabolic process GO:0006200 11 8 0,000 0,04024055 0,08824746 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04024055 0,08816831 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04024055 0,08808931 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04024055 0,08801045 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04024055 0,08793173 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04024055 0,08785315 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04024055 0,08777471 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04024055 0,08769641 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04024055 0,08761825 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04024055 0,08754022 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04024055 0,08746234 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04024055 0,0873846 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04024055 0,08730699 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04024055 0,08722952 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04024055 0,08715219 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04024055 0,087075 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04024055 0,08699794 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04024055 0,08692102 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04024055 0,08684423 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,04273591 0,09214813 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,04394754 0,09467711 GO:0048609|reproductive process in a multicellular organism, ! axon extension GO:0048675 16 9 0,000 0,04515603 0,09719486 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04515603 0,0971093 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04515603 0,0970239 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04515603 0,09693864 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04515603 0,09685353 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04515603 0,09676857 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04515603 0,09668376 ! reproductive behavior GO:0019098 22 9 0,000 0,04515603 0,0965991 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04515603 0,09651458 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04515603 0,09643022 ! UTP metabolic process GO:0046051 10 9 0,000 0,04515603 0,096346 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04515603 0,09626193 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04515603 0,096178 ! artery development GO:0060840 25 9 0,000 0,04515603 0,09609422 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04515603 0,09601059 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04515603 0,0959271 ! equilibrioception GO:0050957 20 9 0,000 0,04515603 0,09584376 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04515603 0,09576056 ! chemosensory behavior GO:0007635 21 9 0,000 0,04515603 0,09567751 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04515603 0,0955946 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04515603 0,09551184 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04515603 0,09542921 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04515603 0,09534673 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04515603 0,0952644 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04515603 0,0951822 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04515603 0,09510015 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04515603 0,09501823 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04515603 0,09493646 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04515603 0,09485483 ! protein targeting to ER GO:0045047 25 9 0,000 0,04515603 0,09477334 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04515603 0,09469199 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04515603 0,09461078 ! T cell selection GO:0045058 27 9 0,000 0,04515603 0,09452971 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04515603 0,09444878 ! glycine catabolic process GO:0006546 15 9 0,000 0,04515603 0,09436798 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04515603 0,09428732 ! endosome organization GO:0007032 20 9 0,000 0,04515603 0,09420681 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04515603 0,09412642 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04515603 0,09404618 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04515603 0,09396607 ! mannose metabolic process GO:0006013 13 9 0,000 0,04515603 0,0938861 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04515603 0,09380627 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04515603 0,09372657 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04515603 0,093647 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04515603 0,09356757 ! receptor clustering GO:0043113 20 9 0,000 0,04515603 0,09348828 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04515603 0,09340912 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04515603 0,09333009 ! retinol metabolic process GO:0042572 20 9 0,000 0,04515603 0,0932512 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04515603 0,09317244 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04515603 0,09309381 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04515603 0,09301532 ! macrophage differentiation GO:0030225 15 9 0,000 0,04515603 0,09293696 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04515603 0,09285873 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04515603 0,09278063 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04515603 0,09270266 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04515603 0,09262483 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04515603 0,09254712 ! response to amine stimulus GO:0014075 13 9 0,000 0,04515603 0,09246955 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04515603 0,0923921 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04515603 0,09231479 ! erythrocyte development GO:0048821 17 9 0,000 0,04515603 0,0922376 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04515603 0,09216054 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04515603 0,09208361 ! renal water homeostasis GO:0003091 15 9 0,000 0,04515603 0,09200681 ! postreplication repair GO:0006301 25 9 0,000 0,04515603 0,09193014 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04515603 0,0918536 ! icosanoid secretion GO:0032309 15 9 0,000 0,04515603 0,09177718 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04515603 0,09170089 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04515603 0,09162473 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04515603 0,09154869 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04515603 0,09147278 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04515603 0,09139699 ! sterol catabolic process GO:0016127 14 9 0,000 0,04515603 0,09132133 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04515603 0,0912458 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04515603 0,09117039 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04515603 0,0910951 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04515603 0,09101994 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04515603 0,0909449 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04515603 0,09086999 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04515603 0,0907952 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04515603 0,09072053 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04515603 0,09064599 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04515603 0,09057157 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04515603 0,09049727 ! purine base metabolic process GO:0006144 25 9 0,000 0,04515603 0,09042309 ! pigment granule transport GO:0051904 17 9 0,000 0,04515603 0,09034903 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04515603 0,0902751 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04515603 0,09020128 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04515603 0,09012759 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04515603 0,09005402 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04515603 0,08998056 ! ear development GO:0043583 114 66 1,000 0,04517186 0,08993876 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,04517186 0,08986552 ! gonad development GO:0008406 115 66 1,000 0,04517186 0,0897924 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,04640871 0,092176 ! secondary metabolic process GO:0019748 125 67 1,000 0,04640871 0,09210112 ! detection of external stimulus GO:0009581 102 68 1,000 0,04765793 0,0945035 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04765793 0,09442686 ! adaptive immune response GO:0002250 126 68 1,000 0,04765793 0,09435034 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,04765793 0,09427394 ! urogenital system development GO:0001655 149 69 1,000 0,04891936 0,09669093 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,04891936 0,09661276 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05004646 0,09875889 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05004646 0,09867918 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,05004646 0,0985996 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05004646 0,09852015 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05004646 0,09844082 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05004646 0,09836163 ! associative learning GO:0008306 21 10 0,000 0,05004646 0,09828256 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,05004646 0,09820362 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05004646 0,0981248 ! phosphate transport GO:0006817 24 10 0,000 0,05004646 0,09804611 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05004646 0,09796755 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05004646 0,09788911 ! CTP metabolic process GO:0046036 11 10 0,000 0,05004646 0,0978108 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,05004646 0,09773262 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05004646 0,09765455 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05004646 0,09757662 ! social behavior GO:0035176 29 10 0,000 0,05004646 0,09749881 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05004646 0,09742112 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05004646 0,09734355 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05004646 0,09726611 ! androgen metabolic process GO:0008209 17 10 0,000 0,05004646 0,09718879 ! phospholipid efflux GO:0033700 19 10 0,000 0,05004646 0,0971116 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05004646 0,09703453 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05004646 0,09695757 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05004646 0,09688075 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05004646 0,09680404 ! pathogenesis GO:0009405 17 10 0,000 0,05004646 0,09672745 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05004646 0,09665099 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05004646 0,09657465 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05004646 0,09649842 ! endoderm development GO:0007492 18 10 0,000 0,05004646 0,09642232 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05004646 0,09634634 ! arginine catabolic process GO:0006527 17 10 0,000 0,05004646 0,09627047 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05004646 0,09619473 ! proline metabolic process GO:0006560 13 10 0,000 0,05004646 0,09611911 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05004646 0,0960436 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05004646 0,09596821 ! V(D)J recombination GO:0033151 34 10 0,000 0,05004646 0,09589294 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05004646 0,09581779 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05004646 0,09574276 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05004646 0,09566784 ! B cell proliferation GO:0042100 19 10 0,000 0,05004646 0,09559304 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05004646 0,09551836 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05004646 0,0954438 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05004646 0,09536935 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05004646 0,09529501 ! ruffle organization GO:0031529 17 10 0,000 0,05004646 0,0952208 ! epithelial cell development GO:0002064 21 10 0,000 0,05004646 0,09514669 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05004646 0,09507271 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05004646 0,09499884 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05004646 0,09492508 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05004646 0,09485144 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05004646 0,09477791 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05004646 0,09470449 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 17 10 0,000 0,05004646 0,09463119 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05004646 0,09455801 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05004646 0,09448493 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05004646 0,09441197 ! segment specification GO:0007379 15 10 0,000 0,05004646 0,09433912 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05004646 0,09426639 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05004646 0,09419376 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05004646 0,09412125 ! response to dsRNA GO:0043331 23 10 0,000 0,05004646 0,09404885 ! DNA ligation GO:0006266 18 10 0,000 0,05004646 0,09397656 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05004646 0,09390438 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05004646 0,09383231 ! melanosome localization GO:0032400 16 10 0,000 0,05004646 0,09376035 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05004646 0,09368851 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05004646 0,09361677 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05004646 0,09354514 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05004646 0,09347363 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05004646 0,09340222 ! induction of an organ GO:0001759 17 10 0,000 0,05004646 0,09333092 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05004646 0,09325973 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05004646 0,09318864 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05004646 0,09311767 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05004646 0,09304681 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05004646 0,09297605 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05004646 0,0929054 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05004646 0,09283485 ! salivary gland development GO:0007431 28 10 0,000 0,05004646 0,09276442 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05004646 0,09269409 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05004646 0,09262387 ! midbrain development GO:0030901 14 10 0,000 0,05004646 0,09255375 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05004646 0,09248374 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05004646 0,09241383 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05004646 0,09234403 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05004646 0,09227434 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05004646 0,09220475 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05004646 0,09213527 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05004646 0,09206589 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05004646 0,09199662 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05004646 0,09192745 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05004646 0,09185838 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05004646 0,09178942 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05004646 0,09172056 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05004646 0,0916518 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05004646 0,09158315 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05004646 0,0915146 ! response to nicotine GO:0035094 20 10 0,000 0,05004646 0,09144615 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05004646 0,0913778 ! carbohydrate transport GO:0008643 114 72 1,000 0,05277536 0,09628843 ! B cell activation GO:0042113 179 72 1,000 0,05277536 0,09621657 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05491198 0,10003727 ! respiratory burst GO:0045730 17 11 0,000 0,05491198 0,09996273 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05491198 0,09988829 ! neuron fate specification GO:0048665 18 11 0,000 0,05491198 0,09981397 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05491198 0,09973976 ! thyroid gland development GO:0030878 26 11 0,000 0,05491198 0,09966566 ! synapsis GO:0007129 14 11 0,000 0,05491198 0,09959167 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05491198 0,09951779 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05491198 0,09944402 ! response to pain GO:0048265 27 11 0,000 0,05491198 0,09937035 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05491198 0,0992968 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05491198 0,09922336 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,05491198 0,09915002 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05491198 0,09907679 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05491198 0,09900367 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05491198 0,09893066 ! histidine metabolic process GO:0006547 22 11 0,000 0,05491198 0,09885776 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05491198 0,09878496 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05491198 0,09871227 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05491198 0,09863969 ! UV protection GO:0009650 20 11 0,000 0,05491198 0,09856721 ! adult heart development GO:0007512 16 11 0,000 0,05491198 0,09849484 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05491198 0,09842258 ! macroautophagy GO:0016236 19 11 0,000 0,05491198 0,09835042 ! temperature homeostasis GO:0001659 18 11 0,000 0,05491198 0,09827837 ! behavioral fear response GO:0001662 27 11 0,000 0,05491198 0,09820643 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05491198 0,09813459 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05491198 0,09806285 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05491198 0,09799122 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05491198 0,09791969 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05491198 0,09784827 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05491198 0,09777695 ! regulation of organ growth GO:0046620 14 11 0,000 0,05491198 0,09770574 ! pigment granule localization GO:0051875 20 11 0,000 0,05491198 0,09763463 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05491198 0,09756362 ! vasoconstriction GO:0042310 20 11 0,000 0,05491198 0,09749272 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05491198 0,09742192 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05491198 0,09735122 ! embryonic axis specification GO:0000578 19 11 0,000 0,05491198 0,09728062 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05491198 0,09721013 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05491198 0,09713974 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05491198 0,09706945 ! DNA methylation GO:0006306 19 11 0,000 0,05491198 0,09699926 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05491198 0,09692917 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05491198 0,09685919 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05491198 0,09678931 ! prophase GO:0051324 17 11 0,000 0,05491198 0,09671952 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05491198 0,09664984 ! nucleosome positioning GO:0016584 15 11 0,000 0,05491198 0,09658026 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05491198 0,09651078 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05491198 0,09644139 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05491198 0,09637211 ! acid secretion GO:0046717 20 11 0,000 0,05491198 0,09630293 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05491198 0,09623384 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05491198 0,09616486 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05491198 0,09609597 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05491198 0,09602719 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05491198 0,0959585 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05491198 0,09588991 ! cholesterol efflux GO:0033344 21 11 0,000 0,05491198 0,09582141 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05491198 0,09575302 ! germ cell migration GO:0008354 26 11 0,000 0,05491198 0,09568472 ! embryonic gut development GO:0048566 19 11 0,000 0,05491198 0,09561652 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05491198 0,09554842 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05491198 0,09548041 ! activation of innate immune response GO:0002218 16 11 0,000 0,05491198 0,0954125 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05491198 0,09534469 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05491198 0,09527697 ! lysogeny GO:0030069 22 11 0,000 0,05491198 0,09520935 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05491198 0,09514183 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05491198 0,0950744 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05491198 0,09500707 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05491198 0,09493983 ! nucleus localization GO:0051647 22 11 0,000 0,05491198 0,09487269 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,05673572 0,09795433 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,05807833 0,10020153 ! learning or memory GO:0007611 161 76 1,000 0,05807833 0,10013081 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,05807833 0,1000602 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,05943194 0,1023201 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05975272 0,10279993 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05975272 0,10272759 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05975272 0,10265535 ! virus-host interaction GO:0019048 30 12 0,000 0,05975272 0,10258321 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05975272 0,10251117 ! mating GO:0007618 17 12 0,000 0,05975272 0,10243923 ! protein complex disassembly GO:0043241 28 12 0,000 0,05975272 0,1023674 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05975272 0,10229566 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05975272 0,10222402 ! hippocampus development GO:0021766 29 12 0,000 0,05975272 0,10215249 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05975272 0,10208105 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05975272 0,10200972 ! T cell proliferation GO:0042098 32 12 0,000 0,05975272 0,10193848 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05975272 0,10186735 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05975272 0,10179631 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05975272 0,10172537 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05975272 0,10165453 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05975272 0,10158379 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05975272 0,10151315 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05975272 0,1014426 ! focal adhesion formation GO:0048041 37 12 0,000 0,05975272 0,10137216 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05975272 0,10130181 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05975272 0,10123156 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05975272 0,1011614 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 21 12 0,000 0,05975272 0,10109135 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05975272 0,10102139 ! entry into host cell GO:0030260 34 12 0,000 0,05975272 0,10095153 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05975272 0,10088176 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05975272 0,10081209 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05975272 0,10074252 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05975272 0,10067304 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05975272 0,10060366 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05975272 0,10053437 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05975272 0,10046518 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05975272 0,10039608 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05975272 0,10032708 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05975272 0,10025818 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05975272 0,10018937 ! cranial nerve development GO:0021545 23 12 0,000 0,05975272 0,10012065 ! fucose catabolic process GO:0019317 25 12 0,000 0,05975272 0,10005203 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05975272 0,0999835 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05975272 0,09991506 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05975272 0,09984672 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05975272 0,09977847 ! zymogen activation GO:0031638 18 12 0,000 0,05975272 0,09971032 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05975272 0,09964226 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05975272 0,09957429 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05975272 0,09950641 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05975272 0,09943863 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05975272 0,09937094 ! defense response to fungus GO:0050832 15 12 0,000 0,05975272 0,09930334 ! developmental induction GO:0031128 22 12 0,000 0,05975272 0,09923583 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,05975272 0,09916841 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05975272 0,09910109 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05975272 0,09903386 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,06217155 0,10297295 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,06355728 0,10519677 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,06355728 0,10512554 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06456881 0,10672638 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06456881 0,10665422 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06456881 0,10658216 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06456881 0,10651019 ! peroxisomal transport GO:0043574 28 13 0,000 0,06456881 0,10643832 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06456881 0,10636655 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06456881 0,10629487 ! organelle fusion GO:0048284 36 13 0,000 0,06456881 0,1062233 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06456881 0,10615181 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06456881 0,10608043 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06456881 0,10600914 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06456881 0,10593794 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06456881 0,10586684 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06456881 0,10579584 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06456881 0,10572493 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06456881 0,10565411 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06456881 0,1055834 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06456881 0,10551277 ! methionine metabolic process GO:0006555 31 13 0,000 0,06456881 0,10544224 ! plasma membrane organization GO:0007009 27 13 0,000 0,06456881 0,10537181 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06456881 0,10530146 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06456881 0,10523122 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06456881 0,10516106 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06456881 0,105091 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,06456881 0,10502103 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06456881 0,10495116 ! exocrine system development GO:0035272 34 13 0,000 0,06456881 0,10488138 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06456881 0,10481169 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06456881 0,10474209 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06456881 0,10467259 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06456881 0,10460318 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06456881 0,10453386 ! protein homotetramerization GO:0051289 24 13 0,000 0,06456881 0,10446463 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06456881 0,1043955 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06456881 0,10432645 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06456881 0,1042575 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06456881 0,10418863 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06456881 0,10411986 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06456881 0,10405118 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06456881 0,10398259 ! histone methylation GO:0016571 29 13 0,000 0,06456881 0,10391409 ! chromatin silencing GO:0006342 29 13 0,000 0,06456881 0,10384568 ! gland morphogenesis GO:0022612 31 13 0,000 0,06456881 0,10377736 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06456881 0,10370913 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06456881 0,10364099 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06456881 0,10357294 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06456881 0,10350498 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06456881 0,10343711 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06456881 0,10336933 ! spleen development GO:0048536 24 13 0,000 0,06456881 0,10330163 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06456881 0,10323403 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06456881 0,10316651 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06456881 0,10309908 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06456881 0,10303174 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06456881 0,10296449 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06456881 0,10289732 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06456881 0,10283024 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06456881 0,10276325 ! insulin secretion GO:0030073 24 13 0,000 0,06456881 0,10269635 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06456881 0,10262953 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06456881 0,1025628 ! acrosome reaction GO:0007340 19 13 0,000 0,06456881 0,10249616 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06456881 0,10242961 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06456881 0,10236314 ! meiosis GO:0007126 143 81 1,000 0,06495342 0,1029061 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 1,000 0,06635984 0,10506616 ! meiotic cell cycle GO:0051321 144 82 1,000 0,06635984 0,10499811 ! response to metal ion GO:0010038 158 84 1,000 0,06920294 0,10942575 ! T cell activation GO:0042110 189 84 1,000 0,06920294 0,10935497 ! response to nutrient GO:0007584 135 84 1,000 0,06920294 0,10928428 ! rRNA transcription GO:0009303 28 14 0,000 0,06936035 0,10946211 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06936035 0,10939144 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,06936035 0,10932087 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06936035 0,10925038 ! non-recombinational repair GO:0000726 29 14 0,000 0,06936035 0,10917999 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06936035 0,10910969 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06936035 0,10903947 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06936035 0,10896935 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06936035 0,10889932 ! lipid localization GO:0010876 32 14 0,000 0,06936035 0,10882938 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06936035 0,10875953 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06936035 0,10868977 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06936035 0,10862009 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06936035 0,10855051 ! arginine metabolic process GO:0006525 21 14 0,000 0,06936035 0,10848101 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06936035 0,10841161 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06936035 0,10834229 ! regulation of heart rate GO:0002027 25 14 0,000 0,06936035 0,10827306 ! fear response GO:0042596 34 14 0,000 0,06936035 0,10820392 ! organic alcohol transport GO:0015850 29 14 0,000 0,06936035 0,10813487 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06936035 0,10806591 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06936035 0,10799703 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06936035 0,10792824 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06936035 0,10785954 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06936035 0,10779093 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06936035 0,10772241 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06936035 0,10765397 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06936035 0,10758562 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06936035 0,10751735 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06936035 0,10744917 ! ribosome assembly GO:0042255 18 14 0,000 0,06936035 0,10738108 ! cerebellum development GO:0021549 23 14 0,000 0,06936035 0,10731307 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06936035 0,10724515 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06936035 0,10717732 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06936035 0,10710957 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06936035 0,10704191 ! NADP metabolic process GO:0006739 24 14 0,000 0,06936035 0,10697433 ! oxygen transport GO:0015671 22 14 0,000 0,06936035 0,10690684 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06936035 0,10683943 ! male genitalia development GO:0030539 26 14 0,000 0,06936035 0,10677211 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06936035 0,10670488 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06936035 0,10663772 ! negative regulation of growth GO:0045926 168 85 1,000 0,07063935 0,10853581 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07412749 0,11382367 ! lactation GO:0007595 30 15 0,000 0,07412749 0,11375217 ! reproductive cellular process GO:0048610 22 15 0,000 0,07412749 0,11368077 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07412749 0,11360945 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07412749 0,11353822 ! superoxide anion generation GO:0042554 22 15 0,000 0,07412749 0,11346708 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07412749 0,11339603 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07412749 0,11332507 ! copper ion transport GO:0006825 22 15 0,000 0,07412749 0,1132542 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07412749 0,11318341 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07412749 0,11311272 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07412749 0,11304211 ! sulfate transport GO:0008272 27 15 0,000 0,07412749 0,11297159 ! response to cAMP GO:0051591 25 15 0,000 0,07412749 0,11290116 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07412749 0,11283082 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07412749 0,11276056 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07412749 0,11269039 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07412749 0,11262031 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07412749 0,11255032 ! vesicle coating GO:0006901 38 15 0,000 0,07412749 0,11248041 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07412749 0,11241059 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07412749 0,11234086 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07412749 0,11227121 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07412749 0,11220165 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07412749 0,11213217 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07412749 0,11206279 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07412749 0,11199348 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07412749 0,11192427 ! histone deacetylation GO:0016575 24 15 0,000 0,07412749 0,11185513 ! water homeostasis GO:0030104 28 15 0,000 0,07412749 0,11178609 ! cofactor transport GO:0051181 30 15 0,000 0,07412749 0,11171713 ! muscle maintenance GO:0046716 26 15 0,000 0,07412749 0,11164825 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07412749 0,11157946 ! intestinal absorption GO:0050892 31 15 0,000 0,07412749 0,11151075 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07412749 0,11144213 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07412749 0,11137359 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07412749 0,11130514 ! cell killing GO:0001906 32 15 0,000 0,07412749 0,11123677 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07412749 0,11116849 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07412749 0,11110028 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07412749 0,11103217 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07412749 0,11096413 ! actin filament polymerization GO:0030041 27 15 0,000 0,07412749 0,11089618 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07412749 0,11082831 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,07500637 0,11207373 ! tube morphogenesis GO:0035239 194 89 1,000 0,07648085 0,11420704 ! response to inorganic substance GO:0010035 173 90 1,000 0,07796452 0,11635145 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,07796452 0,11628042 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07887034 0,11755964 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07887034 0,11748796 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07887034 0,11741636 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07887034 0,11734485 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07887034 0,11727343 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07887034 0,1172021 ! bone remodeling GO:0046849 28 16 0,000 0,07887034 0,11713085 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07887034 0,11705969 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07887034 0,11698862 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07887034 0,11691763 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07887034 0,11684673 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07887034 0,11677591 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07887034 0,11670518 ! startle response GO:0001964 28 16 0,000 0,07887034 0,11663453 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07887034 0,11656397 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07887034 0,1164935 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07887034 0,11642311 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07887034 0,11635281 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07887034 0,11628259 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07887034 0,11621245 ! lysosomal transport GO:0007041 31 16 0,000 0,07887034 0,11614241 ! fructose metabolic process GO:0006000 25 16 0,000 0,07887034 0,11607244 ! L-amino acid transport GO:0015807 33 16 0,000 0,07887034 0,11600256 ! stem cell development GO:0048864 46 16 0,000 0,07887034 0,11593276 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07887034 0,11586305 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07887034 0,11579342 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07887034 0,11572387 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07887034 0,11565441 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07887034 0,11558503 ! axon cargo transport GO:0008088 46 16 0,000 0,07887034 0,11551574 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07887034 0,11544652 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07887034 0,1153774 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,07887034 0,11530835 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07887034 0,11523938 ! tissue regeneration GO:0042246 27 16 0,000 0,07887034 0,1151705 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07887034 0,1151017 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07887034 0,11503299 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07887034 0,11496435 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07887034 0,1148958 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07887034 0,11482732 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07887034 0,11475893 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07887034 0,11469063 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07887034 0,1146224 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07887034 0,11455425 ! peptide hormone processing GO:0016486 27 16 0,000 0,07887034 0,11448619 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,08095889 0,11744808 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08358903 0,1211917 ! metencephalon development GO:0022037 32 17 0,000 0,08358903 0,12111982 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08358903 0,12104802 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,08358903 0,12097631 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08358903 0,12090468 ! signal complex assembly GO:0007172 47 17 0,000 0,08358903 0,12083314 ! filopodium assembly GO:0046847 42 17 0,000 0,08358903 0,12076168 ! endothelial cell migration GO:0043542 31 17 0,000 0,08358903 0,12069031 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08358903 0,12061902 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08358903 0,12054782 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08358903 0,1204767 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08358903 0,12040567 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08358903 0,12033471 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08358903 0,12026384 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08358903 0,12019306 ! myoblast differentiation GO:0045445 50 17 0,000 0,08358903 0,12012236 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08358903 0,12005174 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08358903 0,1199812 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08358903 0,11991075 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08358903 0,11984038 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08358903 0,11977009 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08358903 0,11969989 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08358903 0,11962976 ! membrane budding GO:0006900 42 17 0,000 0,08358903 0,11955972 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08358903 0,11948976 ! regulation of protein binding GO:0043393 33 17 0,000 0,08358903 0,11941989 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08358903 0,11935009 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08358903 0,11928038 ! genitalia development GO:0048806 32 17 0,000 0,08358903 0,11921075 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08358903 0,1191412 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08358903 0,11907172 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08358903 0,11900234 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08358903 0,11893303 ! steroid catabolic process GO:0006706 34 17 0,000 0,08358903 0,1188638 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08358903 0,11879465 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08358903 0,11872559 ! gas transport GO:0015669 26 17 0,000 0,08358903 0,1186566 ! organic cation transport GO:0015695 32 17 0,000 0,08358903 0,11858769 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08358903 0,11851887 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08358903 0,11845012 ! female pregnancy GO:0007565 166 94 1,000 0,08398844 0,1189471 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,08398844 0,11887819 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,08551608 0,12097034 ! regulation of T cell activation GO:0050863 175 96 1,000 0,08705213 0,12307197 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08828368 0,12474091 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08828368 0,12466881 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08828368 0,12459679 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08828368 0,12452485 ! adult walking behavior GO:0007628 36 18 0,000 0,08828368 0,12445299 ! heart looping GO:0001947 34 18 0,000 0,08828368 0,12438122 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08828368 0,12430953 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08828368 0,12423792 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08828368 0,1241664 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08828368 0,12409496 ! glycine metabolic process GO:0006544 30 18 0,000 0,08828368 0,1240236 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08828368 0,12395232 ! response to retinoic acid GO:0032526 31 18 0,000 0,08828368 0,12388112 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,08828368 0,12381001 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08828368 0,12373898 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,08828368 0,12366803 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08828368 0,12359716 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08828368 0,12352637 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08828368 0,12345566 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08828368 0,12338503 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08828368 0,12331449 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08828368 0,12324402 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08828368 0,12317364 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,08828368 0,12310333 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08828368 0,12303311 ! detection of bacterium GO:0016045 22 18 0,000 0,08828368 0,12296296 ! nerve development GO:0021675 34 18 0,000 0,08828368 0,1228929 ! defense response to virus GO:0051607 43 18 0,000 0,08828368 0,12282291 ! microspike assembly GO:0030035 46 18 0,000 0,08828368 0,12275301 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08828368 0,12268318 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,08828368 0,12261344 ! transcription initiation GO:0006352 171 97 1,000 0,08859648 0,12297795 ! leukocyte differentiation GO:0002521 232 98 1,000 0,09014898 0,12506188 ! forebrain development GO:0030900 210 98 1,000 0,09014898 0,1249909 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09295441 0,1288075 ! positive regulation of translation GO:0045727 31 19 0,000 0,09295441 0,12873448 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09295441 0,12866155 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09295441 0,12858869 ! neuron maturation GO:0042551 46 19 0,000 0,09295441 0,12851592 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09295441 0,12844323 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09295441 0,12837062 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09295441 0,1282981 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09295441 0,12822565 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09295441 0,12815329 ! inositol metabolic process GO:0006020 33 19 0,000 0,09295441 0,12808101 ! memory GO:0007613 34 19 0,000 0,09295441 0,12800881 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09295441 0,12793669 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09295441 0,12786466 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09295441 0,1277927 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09295441 0,12772083 ! response to vitamin A GO:0033189 32 19 0,000 0,09295441 0,12764903 ! heme metabolic process GO:0042168 40 19 0,000 0,09295441 0,12757732 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09295441 0,12750569 ! response to fungus GO:0009620 26 19 0,000 0,09295441 0,12743414 ! peptide cross-linking GO:0018149 39 19 0,000 0,09295441 0,12736266 ! protein export from nucleus GO:0006611 40 19 0,000 0,09295441 0,12729127 ! heart process GO:0003015 32 19 0,000 0,09295441 0,12721996 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09295441 0,12714873 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09295441 0,12707758 ! visual learning GO:0008542 38 19 0,000 0,09295441 0,1270065 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09295441 0,12693551 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09295441 0,1268646 ! vitamin transport GO:0051180 31 19 0,000 0,09295441 0,12679376 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09295441 0,12672301 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09295441 0,12665233 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09295441 0,12658173 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09295441 0,12651121 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09295441 0,12644077 ! cilium assembly GO:0042384 38 19 0,000 0,09295441 0,12637041 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09295441 0,12630013 ! protein secretion GO:0009306 45 20 0,000 0,09760135 0,13254035 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09760135 0,13246672 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09760135 0,13239316 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09760135 0,13231969 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09760135 0,1322463 ! skin development GO:0043588 42 20 0,000 0,09760135 0,132173 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09760135 0,13209977 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09760135 0,13202663 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09760135 0,13195356 ! response to vitamin GO:0033273 36 20 0,000 0,09760135 0,13188058 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09760135 0,13180768 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,09760135 0,13173486 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09760135 0,13166211 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09760135 0,13158945 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09760135 0,13151687 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,09760135 0,13144437 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09760135 0,13137195 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09760135 0,13129961 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,09760135 0,13122735 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,09760135 0,13115516 ! body fluid secretion GO:0007589 33 20 0,000 0,09760135 0,13108306 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09760135 0,13101104 ! peptide secretion GO:0002790 38 20 0,000 0,09760135 0,13093909 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09760135 0,13086723 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09760135 0,13079544 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09760135 0,13072373 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09760135 0,1306521 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09760135 0,13058055 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09760135 0,13050908 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,09760135 0,13043768 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09760135 0,13036637 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09760135 0,13029513 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09760135 0,13022397 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09760135 0,13015289 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09760135 0,13008188 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09760135 0,13001095 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09760135 0,1299401 ! regulation of cell killing GO:0031341 46 21 0,000 0,1022246 0,13602108 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,1022246 0,13594703 ! hormone secretion GO:0046879 39 21 0,000 0,1022246 0,13587307 ! cAMP metabolic process GO:0046058 41 21 0,000 0,1022246 0,13579919 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,1022246 0,13572538 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,1022246 0,13565166 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,1022246 0,13557801 ! ovarian follicle development GO:0001541 39 21 0,000 0,1022246 0,13550445 ! smooth muscle contraction GO:0006939 48 21 0,000 0,1022246 0,13543097 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,1022246 0,13535756 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,1022246 0,13528424 ! plasma membrane fusion GO:0045026 33 21 0,000 0,1022246 0,13521099 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,1022246 0,13513783 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,1022246 0,13506474 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,1022246 0,13499173 ! sensory perception of pain GO:0019233 33 21 0,000 0,1022246 0,1349188 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,1022246 0,13484595 ! collagen fibril organization GO:0030199 62 21 0,000 0,1022246 0,13477318 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,1022246 0,13470049 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,1022246 0,13462787 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,1022246 0,13455534 ! collagen catabolic process GO:0030574 29 21 0,000 0,1022246 0,13448288 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,1022246 0,1344105 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,1022246 0,13433819 ! sperm-egg recognition GO:0035036 23 21 0,000 0,1022246 0,13426597 ! actin filament-based movement GO:0030048 47 21 0,000 0,1022246 0,13419382 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,1068243 0,1401567 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,1068243 0,14008146 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,1068243 0,14000631 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,1068243 0,13993124 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,1068243 0,13985625 ! microtubule-based transport GO:0010970 59 22 0,000 0,1068243 0,13978134 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,1068243 0,13970651 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,1068243 0,13963176 ! vacuolar transport GO:0007034 41 22 0,000 0,1068243 0,1395571 ! central nervous system neuron development GO:0021954 47 22 0,000 0,1068243 0,13948251 ! fucose metabolic process GO:0006004 44 22 0,000 0,1068243 0,139408 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,1068243 0,13933357 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,1068243 0,13925921 ! ureteric bud development GO:0001657 50 22 0,000 0,1068243 0,13918494 ! stem cell differentiation GO:0048863 57 22 0,000 0,1068243 0,13911075 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,1068243 0,13903664 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,1068243 0,1389626 ! cytolysis GO:0019835 27 22 0,000 0,1068243 0,13888865 ! renal system process GO:0003014 42 22 0,000 0,1068243 0,13881477 ! vasodilation GO:0042311 40 22 0,000 0,1068243 0,13874097 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,1068243 0,13866725 ! G1 phase GO:0051318 44 22 0,000 0,1068243 0,13859361 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,1068243 0,13852005 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,1068243 0,13844656 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,1068243 0,13837315 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,1068243 0,13829982 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,1068243 0,13822657 ! sarcomere organization GO:0045214 32 22 0,000 0,1068243 0,1381534 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,1068243 0,1380803 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,1068243 0,13800728 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,1068243 0,13793434 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,1068243 0,13786147 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,1068243 0,13778868 ! gut development GO:0048565 44 22 0,000 0,1068243 0,13771597 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,1068243 0,13764334 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,1068243 0,13757078 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,1068243 0,1374983 ! protein stabilization GO:0050821 41 22 0,000 0,1068243 0,13742589 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,11140056 0,14323767 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11140056 0,14316232 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11140056 0,14308705 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11140056 0,14301186 ! gluconeogenesis GO:0006094 38 23 0,000 0,11140056 0,14293675 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11140056 0,14286172 ! viral genome replication GO:0019079 44 23 0,000 0,11140056 0,14278677 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11140056 0,14271189 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11140056 0,14263709 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11140056 0,14256238 ! regeneration GO:0031099 42 23 0,000 0,11140056 0,14248774 ! axis specification GO:0009798 43 23 0,000 0,11140056 0,14241317 ! visual behavior GO:0007632 46 23 0,000 0,11140056 0,14233869 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,11140056 0,14226428 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11140056 0,14218996 ! response to ethanol GO:0045471 47 23 0,000 0,11140056 0,14211571 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11140056 0,14204153 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11140056 0,14196744 ! peroxisome organization GO:0007031 43 23 0,000 0,11140056 0,14189342 ! lysosome organization GO:0007040 47 23 0,000 0,11140056 0,14181948 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11140056 0,14174561 ! vesicle targeting GO:0006903 49 23 0,000 0,11140056 0,14167183 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11140056 0,14159811 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11140056 0,14152448 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11140056 0,14145092 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11140056 0,14137744 ! DNA modification GO:0006304 36 23 0,000 0,11140056 0,14130404 ! fatty acid transport GO:0015908 47 23 0,000 0,11140056 0,14123071 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11140056 0,14115746 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11140056 0,14108428 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11140056 0,14101118 ! hormone transport GO:0009914 41 23 0,000 0,11140056 0,14093815 ! cell-cell recognition GO:0009988 28 23 0,000 0,11140056 0,14086521 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11140056 0,14079233 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11140056 0,14071953 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11140056 0,14064681 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11595351 0,14631943 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11595351 0,14624389 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11595351 0,14616843 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11595351 0,14609305 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11595351 0,14601774 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11595351 0,14594251 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11595351 0,14586736 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11595351 0,14579229 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11595351 0,14571729 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11595351 0,14564237 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11595351 0,14556753 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11595351 0,14549277 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11595351 0,14541808 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11595351 0,14534347 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,11595351 0,14526893 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11595351 0,14519447 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11595351 0,14512009 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11595351 0,14504578 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11595351 0,14497155 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11595351 0,1448974 ! membrane depolarization GO:0051899 45 24 0,000 0,11595351 0,14482332 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11595351 0,14474932 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11595351 0,14467539 ! platelet activation GO:0030168 41 24 0,000 0,11595351 0,14460154 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11595351 0,14452776 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11595351 0,14445406 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11595351 0,14438044 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11595351 0,14430689 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,11595351 0,14423341 ! regulation of amine transport GO:0051952 41 24 0,000 0,11595351 0,14416001 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,11595351 0,14408668 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,12048325 0,14963934 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12048325 0,1495633 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,12048325 0,14948734 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12048325 0,14941146 ! leukocyte adhesion GO:0007159 55 25 0,000 0,12048325 0,14933566 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12048325 0,14925993 ! phototransduction GO:0007602 37 25 0,000 0,12048325 0,14918428 ! keratinization GO:0031424 37 25 0,000 0,12048325 0,1491087 ! vacuole organization GO:0007033 49 25 0,000 0,12048325 0,1490332 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12048325 0,14895778 ! receptor metabolic process GO:0043112 53 25 0,000 0,12048325 0,14888244 ! chromosome condensation GO:0030261 48 25 0,000 0,12048325 0,14880717 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12048325 0,14873197 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12048325 0,14865686 ! interaction with host GO:0051701 66 25 0,000 0,12048325 0,14858182 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12048325 0,14850685 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12048325 0,14843196 ! immunoglobulin production GO:0002377 62 25 0,000 0,12048325 0,14835715 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12048325 0,14828241 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12048325 0,14820774 ! liver development GO:0001889 55 25 0,000 0,12048325 0,14813315 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12498991 0,15359675 ! initiation of viral infection GO:0019059 60 26 0,000 0,12498991 0,15351953 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12498991 0,15344239 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12498991 0,15336532 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12498991 0,15328833 ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12498991 0,15321141 ! spinal cord development GO:0021510 54 26 0,000 0,12498991 0,15313458 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12498991 0,15305782 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12498991 0,15298114 ! digestive system process GO:0022600 49 26 0,000 0,12498991 0,15290453 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12498991 0,152828 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,12498991 0,15275155 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12498991 0,15267517 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12498991 0,15259887 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12498991 0,15252265 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12498991 0,1524465 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12498991 0,15237043 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12498991 0,15229444 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12498991 0,15221852 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12498991 0,15214267 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12498991 0,15206691 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,12498991 0,15199121 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12498991 0,1519156 ! telomere organization GO:0032200 46 26 0,000 0,12498991 0,15184005 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12498991 0,15176459 ! neural tube closure GO:0001843 58 26 0,000 0,12498991 0,15168919 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,12498991 0,15161388 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12498991 0,15153863 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12498991 0,15146347 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1294736 0,15681904 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1294736 0,15674133 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1294736 0,1566637 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1294736 0,15658614 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1294736 0,15650867 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1294736 0,15643126 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1294736 0,15635394 ! iron ion transport GO:0006826 65 27 0,000 0,1294736 0,15627669 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1294736 0,15619951 ! tube lumen formation GO:0035148 59 27 0,000 0,1294736 0,15612241 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1294736 0,15604539 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1294736 0,15596845 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1294736 0,15589158 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1294736 0,15581478 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1294736 0,15573807 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,13393445 0,16102453 ! vesicle docking GO:0048278 55 28 0,000 0,13393445 0,16094533 ! circadian rhythm GO:0007623 56 28 0,000 0,13393445 0,1608662 ! fat cell differentiation GO:0045444 57 28 0,000 0,13393445 0,16078715 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13393445 0,16070818 ! sperm motility GO:0030317 37 28 0,000 0,13393445 0,16062929 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13393445 0,16055047 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13393445 0,16047173 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13393445 0,16039307 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13393445 0,16031448 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13393445 0,16023597 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13393445 0,16015754 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13393445 0,16007919 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,13393445 0,16000091 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13393445 0,15992271 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13393445 0,15984458 ! lipid oxidation GO:0034440 48 28 0,000 0,13393445 0,15976653 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13393445 0,15968856 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13393445 0,15961066 ! translational initiation GO:0006413 66 29 0,000 0,13837256 0,16481919 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,13837256 0,16473887 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,13837256 0,16465863 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,13837256 0,16457846 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,13837256 0,16449837 ! primary neural tube formation GO:0014020 61 29 0,000 0,13837256 0,16441836 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,13837256 0,16433843 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,13837256 0,16425858 ! synaptogenesis GO:0007416 46 29 0,000 0,13837256 0,1641788 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,13837256 0,16409911 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,13837256 0,16401948 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,13837256 0,16393994 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,13837256 0,16386047 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14278805 0,16900737 ! phenol metabolic process GO:0018958 56 30 0,000 0,14278805 0,16892552 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14278805 0,16884376 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14278805 0,16876207 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14278805 0,16868047 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,14278805 0,16859894 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,14278805 0,16851749 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14278805 0,16843612 ! acute-phase response GO:0006953 50 30 0,000 0,14278805 0,16835483 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14278805 0,16827362 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14278805 0,16819248 ! myofibril assembly GO:0030239 50 30 0,000 0,14278805 0,16811142 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14278805 0,16803045 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14278805 0,16794955 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14278805 0,16786872 ! cell fate determination GO:0001709 64 30 0,000 0,14278805 0,16778798 ! phospholipid transport GO:0015914 65 30 0,000 0,14278805 0,16770731 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14278805 0,16762672 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14278805 0,16754621 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14278805 0,16746577 ! regulation of B cell activation GO:0050864 55 30 0,000 0,14278805 0,16738542 ! regulation of coagulation GO:0050818 52 30 0,000 0,14278805 0,16730513 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,14718104 0,17236974 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,14718104 0,17228715 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,14718104 0,17220463 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,14718104 0,1721222 ! cell junction assembly GO:0034329 85 31 0,000 0,14718104 0,17203984 ! regulation of innate immune response GO:0045088 57 31 0,000 0,14718104 0,17195757 ! ovulation cycle process GO:0022602 55 31 0,000 0,14718104 0,17187537 ! male gonad development GO:0008584 56 31 0,000 0,14718104 0,17179325 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,14718104 0,17171121 ! detection of light stimulus GO:0009583 44 31 0,000 0,14718104 0,17162925 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,14718104 0,17154736 ! natural killer cell activation GO:0030101 50 31 0,000 0,14718104 0,17146556 ! cofactor catabolic process GO:0051187 54 31 0,000 0,14718104 0,17138383 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,14718104 0,17130218 ! eye morphogenesis GO:0048592 65 31 0,000 0,14718104 0,17122061 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,14718104 0,17113911 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15155164 0,17613732 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15155164 0,17605356 ! collagen metabolic process GO:0032963 49 32 0,000 0,15155164 0,17596989 ! spindle organization GO:0007051 50 32 0,000 0,15155164 0,17588629 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15155164 0,17580278 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15155164 0,17571934 ! metanephros development GO:0001656 81 32 0,000 0,15155164 0,17563598 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,15155164 0,1755527 ! muscle cell development GO:0055001 52 32 0,000 0,15155164 0,1754695 ! mesoderm formation GO:0001707 73 32 0,000 0,15155164 0,17538638 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15155164 0,17530334 ! ovulation cycle GO:0042698 57 32 0,000 0,15155164 0,17522037 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15155164 0,17513749 ! hindbrain development GO:0030902 65 32 0,000 0,15155164 0,17505468 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15155164 0,17497195 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15155164 0,1748893 ! gene silencing GO:0016458 71 32 0,000 0,15155164 0,17480673 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15589996 0,17973742 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15589996 0,17965264 GO:0055092|sterol homeostasis, ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15589996 0,17956794 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15589996 0,17948332 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,15589996 0,17939877 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15589996 0,17931431 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15589996 0,17922993 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15589996 0,17914562 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16022612 0,18403028 ! post-embryonic development GO:0009791 76 34 0,000 0,16022612 0,1839438 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16022612 0,1838574 ! cholesterol transport GO:0030301 62 34 0,000 0,16022612 0,18377108 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16022612 0,18368484 ! spliceosome assembly GO:0000245 75 34 0,000 0,16022612 0,18359869 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16022612 0,18351261 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16022612 0,18342662 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16022612 0,1833407 ! cell fate specification GO:0001708 56 34 0,000 0,16022612 0,18325487 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16022612 0,18316912 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,16022612 0,18308344 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16453022 0,18791367 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16453022 0,18782586 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,16453022 0,18773813 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16453022 0,18765048 ! membrane docking GO:0022406 69 35 0,000 0,16453022 0,18756292 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16453022 0,18747544 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16453022 0,18738803 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,16453022 0,18730072 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16453022 0,18721348 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16453022 0,18712632 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16453022 0,18703924 ! sterol transport GO:0015918 63 35 0,000 0,16453022 0,18695225 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16453022 0,18686533 ! vesicle localization GO:0051648 70 35 0,000 0,16453022 0,1867785 ! regulation of muscle development GO:0048634 82 36 0,000 0,16881239 0,19155071 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,16881239 0,19146178 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,16881239 0,19137293 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,16881239 0,19128417 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,16881239 0,19119549 ! positive regulation of cell development GO:0010720 85 36 0,000 0,16881239 0,19110689 ! protein targeting to membrane GO:0006612 75 36 0,000 0,16881239 0,19101837 ! aerobic respiration GO:0009060 56 36 0,000 0,16881239 0,19092994 ! cytokine production GO:0001816 68 36 0,000 0,16881239 0,19084159 ! embryonic organ development GO:0048568 67 36 0,000 0,16881239 0,19075332 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,16881239 0,19066513 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,16881239 0,19057702 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17307273 0,19529639 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,17307273 0,19520622 ! sister chromatid segregation GO:0000819 65 37 0,000 0,17307273 0,19511614 ! odontogenesis GO:0042476 74 37 0,000 0,17307273 0,19502614 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17307273 0,19493623 ! cell junction organization GO:0034330 96 37 0,000 0,17307273 0,1948464 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,17307273 0,19475665 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17307273 0,19466698 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,17307273 0,1945774 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,17731135 0,19925098 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,17731135 0,19915937 ! meiosis I GO:0007127 74 38 0,000 0,17731135 0,19906785 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,17731135 0,19897641 ! organic anion transport GO:0015711 82 38 0,000 0,17731135 0,19888505 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,17731135 0,19879377 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,17731135 0,19870258 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,17731135 0,19861148 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,17731135 0,19852046 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,17731135 0,19842952 ! regulation of protein stability GO:0031647 77 38 0,000 0,17731135 0,19833866 ! spermatid development GO:0007286 69 38 0,000 0,17731135 0,19824789 ! neural tube formation GO:0001841 79 38 0,000 0,17731135 0,1981572 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18152837 0,20277723 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,18152837 0,20268455 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18152837 0,20259196 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18152837 0,20249945 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18152837 0,20240703 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18152837 0,20231469 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,18152837 0,20222244 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,18572389 0,20680194 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18572389 0,20670772 ! lipid homeostasis GO:0055088 75 40 0,000 0,18572389 0,20661359 ! mismatch repair GO:0006298 58 40 0,000 0,18572389 0,20651955 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,18572389 0,20642559 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,18572389 0,20633172 ! RNA export from nucleus GO:0006405 61 41 0,000 0,18989801 0,21087311 ! mRNA catabolic process GO:0006402 79 41 0,000 0,18989801 0,2107773 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,18989801 0,21068158 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,18989801 0,21058595 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,18989801 0,2104904 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,18989801 0,21039494 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,18989801 0,21029957 ! feeding behavior GO:0007631 69 41 0,000 0,18989801 0,21020428 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,18989801 0,21010908 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,18989801 0,21001396 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,18989801 0,20991894 ! spermatid differentiation GO:0048515 73 41 0,000 0,18989801 0,20982399 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,18989801 0,20972914 ! RNA modification GO:0009451 64 41 0,000 0,18989801 0,20963436 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19405086 0,21412207 ! organic ether metabolic process GO:0018904 59 42 0,000 0,19405086 0,2140254 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19405086 0,21392882 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19405086 0,21383232 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19405086 0,21373591 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19405086 0,21363959 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,19405086 0,21354336 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,19818254 0,21799187 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,19818254 0,21789376 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,19818254 0,21779574 ! regulation of tube size GO:0035150 76 43 0,000 0,19818254 0,21769781 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,19818254 0,21759997 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,19818254 0,21750222 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,19818254 0,21740455 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,19818254 0,21730697 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,19818254 0,21720948 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,19818254 0,21711208 ! ion transmembrane transport GO:0034220 79 43 0,000 0,19818254 0,21701476 ! neuron migration GO:0001764 85 43 0,000 0,19818254 0,21691753 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,19818254 0,21682039 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,20229315 0,22121851 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,20229315 0,22111953 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,20229315 0,22102064 ! striated muscle contraction GO:0006941 85 44 0,000 0,20229315 0,22092184 ! phagocytosis GO:0006909 105 44 0,000 0,20229315 0,22082313 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20229315 0,2207245 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,2063828 0,22508624 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,2063828 0,2249858 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,2063828 0,22488545 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,2063828 0,22478519 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,2063828 0,22468502 ! polyol metabolic process GO:0019751 77 45 0,000 0,2063828 0,22458493 ! maintenance of location in cell GO:0051651 101 45 0,000 0,2063828 0,22448494 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,2104516 0,22880875 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,2104516 0,22870696 ! glycolysis GO:0006096 71 46 0,000 0,2104516 0,22860527 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,2104516 0,22850367 ! neural tube development GO:0021915 91 47 0,000 0,21449965 0,23279549 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,21449965 0,23269212 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,21852707 0,23695589 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,21852707 0,23685076 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,21852707 0,23674573 ! endosome transport GO:0016197 127 48 0,000 0,21852707 0,23664079 ! male sex differentiation GO:0046661 93 48 0,000 0,21852707 0,23653594 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,21852707 0,23643119 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,21852707 0,23632653 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,21852707 0,23622196 ! response to calcium ion GO:0051592 94 49 0,000 0,22253394 0,24044689 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,22253394 0,24034059 ! JNK cascade GO:0007254 106 49 0,000 0,22253394 0,24023439 ! regulation of ion transport GO:0043269 86 50 0,000 0,22652039 0,2444299 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,22652039 0,24432199 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,22652039 0,24421417 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,22652039 0,24410644 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,22652039 0,24399881 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,22652039 0,24389127 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,22652039 0,24378383 ! viral infectious cycle GO:0019058 104 51 0,000 0,2304865 0,24794299 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,2304865 0,24783386 ! peptide metabolic process GO:0006518 80 51 0,000 0,2304865 0,24772482 ! Notch signaling pathway GO:0007219 111 52 0,000 0,23443239 0,25185503 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,23443239 0,25174432 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,23443239 0,25163371 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,23443239 0,2515232 ! excretion GO:0007588 87 52 0,000 0,23443239 0,25141279 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,23443239 0,25130247 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,23443239 0,25119225 ! amino acid activation GO:0043038 98 52 0,000 0,23443239 0,25108213 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,23835816 0,25517484 ! inner ear development GO:0048839 89 53 0,000 0,23835816 0,25506306 ! chromatin remodeling GO:0006338 122 53 0,000 0,23835816 0,25495139 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,23835816 0,25483981 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,23835816 0,25472834 ! regulation of translational initiation GO:0006446 87 54 0,000 0,2422639 0,25878912 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,2422639 0,25867601 ! neuromuscular process GO:0050905 107 54 0,000 0,2422639 0,258563 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,2422639 0,25845009 ! membrane fusion GO:0006944 122 54 0,000 0,2422639 0,25833728 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,2422639 0,25822457 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,2422639 0,25811195 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,2422639 0,25799944 ! RNA catabolic process GO:0006401 103 55 0,000 0,24614973 0,26202344 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,24614973 0,26190931 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,24614973 0,26179529 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,24614973 0,26168137 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,25001574 0,2656757 ! glucose catabolic process GO:0006007 88 56 0,000 0,25001574 0,26556019 ! RNA elongation GO:0006354 90 56 0,000 0,25001574 0,26544478 ! chloride transport GO:0006821 102 57 0,000 0,25386203 0,26941135 ! heart morphogenesis GO:0003007 105 57 0,000 0,25386203 0,26929437 ! regulation of actin filament length GO:0030832 118 58 0,000 0,2576887 0,27323502 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,2576887 0,27311648 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,2576887 0,27299804 ! gastrulation GO:0007369 122 58 0,000 0,2576887 0,27287971 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,2576887 0,27276148 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,2576887 0,27264335 ! maintenance of location GO:0051235 124 58 0,000 0,2576887 0,27252532 ! nuclear export GO:0051168 110 59 0,000 0,26149585 0,27643201 ! establishment of organelle localization GO:0051656 122 59 0,000 0,26149585 0,27631244 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,26528359 0,2801936 ! regulation of endocytosis GO:0030100 104 60 0,000 0,26528359 0,28007252 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,26528359 0,27995153 ! adult behavior GO:0030534 104 60 0,000 0,26528359 0,27983066 ! kidney development GO:0001822 133 60 0,000 0,26528359 0,27970988 ! positive regulation of secretion GO:0051047 110 61 0,000 0,269052 0,28356084 ! regulation of cellular component size GO:0032535 125 61 0,000 0,269052 0,28343857 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,269052 0,28331639 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,269052 0,28319433 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,269052 0,28307237 ! camera-type eye development GO:0043010 126 61 0,000 0,269052 0,28295051 ! proton transport GO:0015992 117 61 0,000 0,269052 0,28282876 ! viral reproductive process GO:0022415 132 62 0,000 0,27280119 0,28664658 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,27280119 0,28652335 ! tRNA processing GO:0008033 102 62 0,000 0,27280119 0,28640022 ! regulation of mitosis GO:0007088 112 63 0,000 0,27653126 0,29019152 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,27653126 0,29006692 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,27653126 0,28994243 ! hydrogen transport GO:0006818 121 64 0,000 0,28024229 0,29370739 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,28024229 0,29358144 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,2839344 0,29732179 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,2839344 0,2971944 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,2839344 0,29706712 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,2839344 0,29693996 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,28760767 0,30065277 ! activation of MAPK activity GO:0000187 124 67 0,000 0,2912622 0,30434284 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,2912622 0,30421272 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,2912622 0,30408271 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,2912622 0,30395282 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,2912622 0,30382304 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,2912622 0,30369336 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,29489808 0,30735325 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,29489808 0,30722218 ! hexose catabolic process GO:0019320 113 68 0,000 0,29489808 0,30709123 ! extracellular matrix organization GO:0030198 146 68 0,000 0,29489808 0,30696038 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,29489808 0,30682965 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,29489808 0,30669903 ! viral reproduction GO:0016032 142 68 0,000 0,29489808 0,30656852 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,29489808 0,30643812 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,29851542 0,31006512 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,29851542 0,30993335 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,29851542 0,30980168 ! single fertilization GO:0007338 83 69 0,000 0,29851542 0,30967013 ! cell redox homeostasis GO:0045454 114 70 0,000 0,30211429 0,31327047 ! activation of immune response GO:0002253 120 70 0,000 0,30211429 0,31313756 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,30211429 0,31300476 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,30569481 0,31658009 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,30569481 0,31644594 ! appendage morphogenesis GO:0035107 150 72 0,000 0,30925706 0,31999788 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 0,000 0,30925706 0,3198624 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,30925706 0,31972704 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,30925706 0,31959179 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,30925706 0,31945665 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,30925706 0,31932163 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,30925706 0,31918673 ! appendage development GO:0048736 151 73 0,000 0,31280112 0,32270826 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,31280112 0,32257203 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,31280112 0,32243593 ! regulation of immune effector process GO:0002697 156 73 0,000 0,31280112 0,32229994 ! acute inflammatory response GO:0002526 118 74 0,000 0,31632711 0,32579559 ! amino acid transport GO:0006865 148 74 0,000 0,31632711 0,32565829 ! transition metal ion transport GO:0000041 143 75 0,000 0,3198351 0,32913107 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,3198351 0,32899249 ! eye development GO:0001654 155 75 0,000 0,3198351 0,32885402 ! rhythmic process GO:0048511 142 75 0,000 0,3198351 0,32871567 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,32332519 0,33216293 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,32332519 0,3320233 ! regulation of blood pressure GO:0008217 134 76 0,000 0,32332519 0,3318838 ! amine catabolic process GO:0009310 136 77 0,000 0,32679747 0,33530711 ! neurotransmitter transport GO:0006836 142 77 0,000 0,32679747 0,33516634 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,32679747 0,33502569 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,32679747 0,33488516 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,32679747 0,33474475 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,32679747 0,33460445 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,33025203 0,33799988 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33025203 0,33785834 ! fertilization GO:0009566 99 78 0,000 0,33025203 0,33771692 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,33025203 0,33757561 ! blood coagulation GO:0007596 151 79 0,000 0,33368896 0,3409461 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,33368896 0,34080357 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,33368896 0,34066115 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,33368896 0,34051885 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,33368896 0,34037667 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,33710835 0,34372107 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,33710835 0,34357768 ! muscle cell differentiation GO:0042692 178 81 0,000 0,34051028 0,34690018 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,34051028 0,34675558 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,34726216 0,35348394 ! exocytosis GO:0006887 153 83 0,000 0,34726216 0,35333671 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,34726216 0,35318961 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,34726216 0,35304263 ! inorganic anion transport GO:0015698 156 83 0,000 0,34726216 0,35289578 ! digestion GO:0007586 130 84 0,000 0,35061227 0,35615209 ! regulation of ligase activity GO:0051340 147 84 0,000 0,35061227 0,35600406 ! hemostasis GO:0007599 165 85 0,000 0,35394528 0,35923902 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,35394528 0,35908983 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,35394528 0,35894077 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,35394528 0,35879183 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,35726128 0,36200303 ! regulation of lyase activity GO:0051339 169 86 0,000 0,35726128 0,36185294 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,35726128 0,36170298 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,36056035 0,36489185 ! alcohol catabolic process GO:0046164 142 87 0,000 0,36056035 0,36474076 ! nucleosome assembly GO:0006334 126 87 0,000 0,36056035 0,36458979 ! cellular respiration GO:0045333 143 88 0,000 0,36384258 0,36775648 ! sensory perception of smell GO:0007608 117 88 0,000 0,36384258 0,36760439 ! chromatin assembly GO:0031497 128 88 0,000 0,36384258 0,36745242 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,36710805 0,37059709 ! cellular defense response GO:0006968 123 89 0,000 0,36710805 0,37044402 ! regulation of neurological system process GO:0031644 175 89 0,000 0,36710805 0,37029107 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,37035685 0,37341387 ! response to unfolded protein GO:0006986 139 90 0,000 0,37035685 0,37325982 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,37358907 0,3763621 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,37358907 0,37620697 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,37680479 0,37928887 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,38000409 0,38235172 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,38000409 0,38219431 ! vitamin metabolic process GO:0006766 153 93 0,000 0,38000409 0,38203703 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,38318705 0,38507855 ! sterol metabolic process GO:0016125 166 94 0,000 0,38318705 0,38492022 ! nucleosome organization GO:0034728 143 95 0,000 0,38635376 0,38794174 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,38635376 0,38778235 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,38635376 0,3876231 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,38635376 0,38746398 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,38635376 0,38730498 ! response to protein stimulus GO:0051789 158 96 0,000 0,38950431 0,39030313 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,39263876 0,3932827 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,39575721 0,3962438 ! mRNA transport GO:0051028 185 100 0,000 0,40194643 0,40227576 ! positive regulation of immune response GO:0050778 175 100 0,000 0,40194643 0,40211102 ! hormone metabolic process GO:0042445 171 100 0,000 0,40194643 0,40194643