pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6334-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 8,676E-11 2,088E-07 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 3,616E-09 4,35E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 8,496E-09 6,814E-06 ! cell killing GO:0001906 29 15 3,000 2,332E-08 1,403E-05 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,703E-07 8,193E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 4,849E-07 1,944E-04 ! spindle organization GO:0007051 46 32 3,000 5,981E-07 2,056E-04 ! receptor clustering GO:0043113 18 9 2,000 7,262E-07 2,184E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 8,211E-07 2,195E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,537E-06 3,697E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 3,123E-06 6,832E-04 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 29 14 2,000 3,123E-06 6,262E-04 ! positive regulation of biomineral formation GO:0070169 30 15 2,000 3,898E-06 7,215E-04 ! signal complex assembly GO:0007172 41 17 2,000 5,809E-06 9,983E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 5,809E-06 9,317E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 6,318E-06 9,501E-04 ! neuromuscular junction development GO:0007528 34 19 2,000 8,253E-06 1,168E-03 ! positive regulation of ossification GO:0045778 47 20 2,000 9,695E-06 1,296E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 9,695E-06 1,228E-03 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 1,005E-05 1,209E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 1,129E-05 1,294E-03 ! positive regulation of bone remodeling GO:0046852 51 22 2,000 1,306E-05 1,428E-03 GO:0034105|positive regulation of tissue remodeling, ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,306E-05 1,366E-03 ! ureteric bud development GO:0001657 43 22 2,000 1,306E-05 1,309E-03 ! regulation of bone mineralization GO:0030500 49 23 2,000 1,499E-05 1,443E-03 ! leukocyte mediated immunity GO:0002443 128 74 3,000 1,792E-05 1,658E-03 ! receptor metabolic process GO:0043112 46 25 2,000 1,941E-05 1,73E-03 ! regulation of biomineral formation GO:0070167 51 25 2,000 1,941E-05 1,668E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,191E-05 1,818E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 2,191E-05 1,757E-03 ! dendrite development GO:0016358 59 28 2,000 2,753E-05 2,137E-03 ! metanephros development GO:0001656 74 32 2,000 4,143E-05 3,115E-03 ! BMP signaling pathway GO:0030509 64 32 2,000 4,143E-05 3,021E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 4,289E-05 3,035E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,289E-05 2,948E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,289E-05 2,867E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 4,289E-05 2,789E-03 ! male sex determination GO:0030238 15 6 1,000 6,425E-05 4,068E-03 ! protein amino acid prenylation GO:0018346 16 6 1,000 6,425E-05 3,964E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 6,442E-05 3,875E-03 ! hormone-mediated signaling GO:0009755 74 41 2,000 8,786E-05 5,156E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 8,983E-05 5,146E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 8,983E-05 5,026E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 8,983E-05 4,912E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 8,983E-05 4,803E-03 ! protein prenylation GO:0018342 18 7 1,000 8,983E-05 4,698E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,014E-04 5,191E-03 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,163E-04 5,827E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,196E-04 5,873E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,196E-04 5,756E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,196E-04 5,643E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,242E-04 5,746E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 1,242E-04 5,637E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,536E-04 6,843E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,536E-04 6,718E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,536E-04 6,598E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 1,536E-04 6,482E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 1,536E-04 6,371E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,536E-04 6,263E-03 ! motor axon guidance GO:0008045 16 9 1,000 1,536E-04 6,158E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,536E-04 6,057E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,536E-04 5,96E-03 ! regulation of ossification GO:0030278 117 50 2,000 1,594E-04 6,087E-03 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,691E-04 6,357E-03 ! positive regulation of growth GO:0045927 90 52 2,000 1,792E-04 6,633E-03 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,792E-04 6,532E-03 ! synapse organization GO:0050808 85 52 2,000 1,792E-04 6,435E-03 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,917E-04 6,783E-03 ! lung alveolus development GO:0048286 26 10 1,000 1,917E-04 6,685E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,917E-04 6,589E-03 GO:0045685|regulation of glial cell differentiation, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,917E-04 6,497E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,917E-04 6,406E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 1,917E-04 6,319E-03 ! heart morphogenesis GO:0003007 97 55 2,000 2,118E-04 6,885E-03 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,234E-04 7,167E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,34E-04 7,408E-03 ! cardiac cell differentiation GO:0035051 31 11 1,000 2,34E-04 7,312E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 2,34E-04 7,218E-03 ! regulation of bone remodeling GO:0046850 137 57 2,000 2,355E-04 7,172E-03 ! muscle fiber development GO:0048747 112 57 2,000 2,355E-04 7,082E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 2,355E-04 6,994E-03 ! regulation of tissue remodeling GO:0034103 140 58 2,000 2,479E-04 7,275E-03 ! kidney development GO:0001822 122 60 2,000 2,742E-04 7,947E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,804E-04 8,032E-03 ! virus-host interaction GO:0019048 29 12 1,000 2,804E-04 7,937E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,804E-04 7,845E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,804E-04 7,755E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,804E-04 7,667E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,804E-04 7,581E-03 GO:0042130|negative regulation of T cell proliferation, ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,879E-04 7,697E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,31E-04 8,75E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,31E-04 8,655E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,31E-04 8,562E-03 ! positive regulation of cell motion GO:0051272 146 64 2,000 3,318E-04 8,493E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,856E-04 9,766E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 3,856E-04 9,664E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,856E-04 9,564E-03 ! urogenital system development GO:0001655 137 69 2,000 4,142E-04 0,01016858 ! positive regulation of cell size GO:0045793 27 15 1,000 4,443E-04 0,01079818 ! heme biosynthetic process GO:0006783 29 15 1,000 4,443E-04 0,01069019 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 4,443E-04 0,01058435 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,071E-04 0,01196167 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,071E-04 0,01184553 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,071E-04 0,01173163 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 5,071E-04 0,0116199 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of catabolic process GO:0009894 161 76 2,000 5,5E-04 0,01248336 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 5,739E-04 0,01290565 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 5,739E-04 0,01278616 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 5,739E-04 0,01266885 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 6,159E-04 0,01347141 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,448E-04 0,0139768 ! porphyrin biosynthetic process GO:0006779 33 18 1,000 6,448E-04 0,01385201 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 6,448E-04 0,01372942 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 6,448E-04 0,01360899 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 6,448E-04 0,01349065 ! skin development GO:0043588 36 19 1,000 7,197E-04 0,01492767 ! lipid phosphorylation GO:0046834 35 19 1,000 7,197E-04 0,01480008 ! heme metabolic process GO:0042168 36 19 1,000 7,197E-04 0,01467466 ! proximal/distal pattern formation GO:0009954 32 19 1,000 7,197E-04 0,01455134 ! tube morphogenesis GO:0035239 176 86 2,000 7,888E-04 0,01581573 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 7,986E-04 0,01587949 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,986E-04 0,01574933 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 7,986E-04 0,01562129 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 7,986E-04 0,01549531 ! negative regulation of T cell activation GO:0050868 40 20 1,000 7,986E-04 0,01537135 ! regulation of DNA binding GO:0051101 155 88 2,000 8,433E-04 0,01610323 ! regulation of vasoconstriction GO:0019229 39 21 1,000 8,815E-04 0,01669931 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 9,683E-04 0,01820119 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 9,683E-04 0,0180601 ! protein stabilization GO:0050821 39 22 1,000 9,683E-04 0,01792117 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,059E-03 0,01945189 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,059E-03 0,01930453 ! sex determination GO:0007530 47 23 1,000 1,059E-03 0,01915938 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,059E-03 0,0190164 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,154E-03 0,02056378 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,154E-03 0,02041257 ! porphyrin metabolic process GO:0006778 46 24 1,000 1,154E-03 0,02026358 GO:0033013|tetrapyrrole metabolic process, ! protein tetramerization GO:0051262 52 24 1,000 1,154E-03 0,02011674 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,186E-03 0,02052607 GO:0060538|skeletal muscle organ development, ! myelination GO:0042552 45 25 1,000 1,252E-03 0,02152464 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,252E-03 0,02137198 ! interaction with host GO:0051701 62 25 1,000 1,252E-03 0,02122147 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,355E-03 0,02279843 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 1,355E-03 0,02264011 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,355E-03 0,02248397 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 1,355E-03 0,02232997 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,461E-03 0,02392008 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 1,461E-03 0,02375846 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,572E-03 0,02538012 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 1,572E-03 0,02521092 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,572E-03 0,02504396 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 1,572E-03 0,0248792 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 1,686E-03 0,02651173 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,686E-03 0,02633958 ! ensheathment of neurons GO:0007272 57 30 1,000 1,804E-03 0,02800119 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 1,804E-03 0,0278217 ! iron ion homeostasis GO:0055072 54 31 1,000 1,926E-03 0,02951126 ! erythrocyte differentiation GO:0030218 55 31 1,000 1,926E-03 0,02932448 ! mesoderm formation GO:0001707 69 31 1,000 1,926E-03 0,02914005 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 1,926E-03 0,02895793 GO:0043433|negative regulation of transcription factor activity, ! pigment biosynthetic process GO:0046148 66 32 1,000 2,051E-03 0,03065532 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,051E-03 0,03046609 ! peripheral nervous system development GO:0007422 64 32 1,000 2,051E-03 0,03027918 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,051E-03 0,03009455 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 2,181E-03 0,03179917 ! formation of primary germ layer GO:0001704 72 33 1,000 2,181E-03 0,03160761 ! negative regulation of protein transport GO:0051224 69 33 1,000 2,181E-03 0,03141834 ! mesoderm morphogenesis GO:0048332 76 34 1,000 2,314E-03 0,03313868 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,314E-03 0,03294259 ! odontogenesis GO:0042476 66 35 1,000 2,451E-03 0,0346869 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,451E-03 0,03448405 ! calcium-mediated signaling GO:0019722 62 35 1,000 2,451E-03 0,03428356 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,451E-03 0,03408539 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 2,592E-03 0,03583478 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 2,592E-03 0,03563001 ! positive regulation of cell development GO:0010720 80 36 1,000 2,592E-03 0,03542756 ! negative regulation of cell activation GO:0050866 65 36 1,000 2,592E-03 0,03522741 ! negative regulation of DNA binding GO:0043392 68 37 1,000 2,736E-03 0,03698143 ! regulation of protein stability GO:0031647 73 37 1,000 2,736E-03 0,03677483 ! pigment metabolic process GO:0042440 80 37 1,000 2,736E-03 0,03657052 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 2,884E-03 0,03833737 ! carbohydrate homeostasis GO:0033500 53 38 1,000 2,884E-03 0,03812672 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 1,000 2,884E-03 0,03791838 ! mammary gland development GO:0030879 86 39 1,000 3,036E-03 0,03969741 ! regulation of action potential in neuron GO:0019228 73 39 1,000 3,036E-03 0,03948283 ! negative regulation of binding GO:0051100 72 40 1,000 3,191E-03 0,0412819 ! mesenchymal cell development GO:0014031 87 40 1,000 3,191E-03 0,04106115 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 3,191E-03 0,04084274 ! regulation of T cell proliferation GO:0042129 71 41 1,000 3,351E-03 0,0426527 ! keratinocyte differentiation GO:0030216 62 41 1,000 3,351E-03 0,04242821 ! regulation of T cell differentiation GO:0045580 70 41 1,000 3,351E-03 0,04220607 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 3,513E-03 0,04402637 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,513E-03 0,04379825 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 3,68E-03 0,04563662 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 3,68E-03 0,04540259 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 3,85E-03 0,04725842 ! maintenance of location in cell GO:0051651 97 44 1,000 3,85E-03 0,04701853 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 4,023E-03 0,04889122 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,201E-03 0,05078845 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 4,201E-03 0,05053451 ! epidermal cell differentiation GO:0009913 68 46 1,000 4,201E-03 0,05028309 ! positive regulation of protein transport GO:0051222 72 46 1,000 4,201E-03 0,05003416 ! endosome transport GO:0016197 108 47 1,000 4,382E-03 0,05193071 ! positive regulation of DNA binding GO:0043388 73 47 1,000 4,382E-03 0,05167614 ! regulation of JNK cascade GO:0046328 94 47 1,000 4,382E-03 0,05142406 ! positive regulation of cell cycle GO:0045787 89 48 1,000 4,566E-03 0,05332777 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 4,566E-03 0,05307015 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 4,566E-03 0,052815 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 4,566E-03 0,0525623 ! protein amino acid lipidation GO:0006497 95 49 1,000 4,754E-03 0,05446489 ! regulation of action potential GO:0001508 95 49 1,000 4,754E-03 0,05420677 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 4,754E-03 0,05395107 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 4,754E-03 0,05369778 ! negative regulation of immune system process GO:0002683 95 50 1,000 4,945E-03 0,05559914 ! positive regulation of binding GO:0051099 78 51 1,000 5,14E-03 0,0575221 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 5,14E-03 0,0572558 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 1,000 5,339E-03 0,05919216 ! cartilage development GO:0051216 90 52 1,000 5,339E-03 0,05892063 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 5,541E-03 0,06086994 ! response to UV GO:0009411 104 53 1,000 5,541E-03 0,06059326 ! activation of phospholipase C activity GO:0007202 103 54 1,000 5,746E-03 0,06255509 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 5,746E-03 0,06227331 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 5,955E-03 0,06424724 ! regulation of protein catabolic process GO:0042176 116 55 1,000 5,955E-03 0,06396042 ! gastrulation GO:0007369 112 55 1,000 5,955E-03 0,06367615 ! regulation of DNA replication GO:0006275 101 56 1,000 6,167E-03 0,06565425 ! lipid modification GO:0030258 97 57 1,000 6,383E-03 0,06765118 ! regulation of phospholipase activity GO:0010517 106 57 1,000 6,383E-03 0,06735446 ! regulation of intracellular transport GO:0032386 101 57 1,000 6,383E-03 0,06706034 ! maintenance of location GO:0051235 118 57 1,000 6,383E-03 0,06676877 ! positive regulation of lipase activity GO:0060193 108 58 1,000 6,602E-03 0,06876177 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 7,05E-03 0,07311516 ! mesoderm development GO:0007498 119 61 1,000 7,279E-03 0,07516842 ! viral reproductive process GO:0022415 126 62 1,000 7,512E-03 0,07723855 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 8,23E-03 0,0842576 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 1,000 8,23E-03 0,08390057 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 8,475E-03 0,08604212 ! actin filament organization GO:0007015 148 66 1,000 8,475E-03 0,0856806 ! regulation of cellular response to stress GO:0080135 128 67 1,000 8,725E-03 0,08782974 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 8,725E-03 0,08746379 ! negative regulation of cell growth GO:0030308 132 67 1,000 8,725E-03 0,08710087 ! activation of MAPK activity GO:0000187 115 67 1,000 8,725E-03 0,08674094 ! lung development GO:0030324 144 67 1,000 8,725E-03 0,08638399 ! homeostasis of number of cells GO:0048872 114 67 1,000 8,725E-03 0,08602995 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 8,725E-03 0,08567881 ! negative regulation of kinase activity GO:0033673 131 68 1,000 8,977E-03 0,0877987 ! viral reproduction GO:0016032 134 68 1,000 8,977E-03 0,08744324 ! regulation of lipase activity GO:0060191 130 68 1,000 8,977E-03 0,08709065 ! negative regulation of cell size GO:0045792 134 69 1,000 9,233E-03 0,0892107 ! cAMP-mediated signaling GO:0019933 120 69 1,000 9,233E-03 0,08885386 ! appendage morphogenesis GO:0035107 135 70 1,000 9,491E-03 0,09098098 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 9,491E-03 0,09061994 ! appendage development GO:0048736 136 71 1,000 9,753E-03 0,09275387 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 9,753E-03 0,0923887 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01001868 0,09452919 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01001868 0,09415993 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01001868 0,09379355 ! respiratory system development GO:0060541 153 72 1,000 0,01001868 0,09343001 ! regulation of blood pressure GO:0008217 125 73 1,000 0,01028713 0,09556305 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,01028713 0,0951955 ! axon guidance GO:0007411 139 73 1,000 0,01028713 0,09483077 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01041623 0,0956544 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01041623 0,09529069 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01041623 0,09492974 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01041623 0,09457152 ! neuron fate determination GO:0048664 7 5 0,000 0,01041623 0,09421599 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01041623 0,09386312 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01041623 0,09351288 ! polyol transport GO:0015791 12 5 0,000 0,01041623 0,09316525 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01041623 0,09282019 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01041623 0,09247768 ! response to superoxide GO:0000303 10 5 0,000 0,01041623 0,09213769 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01041623 0,09180019 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01041623 0,09146516 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01041623 0,09113255 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01041623 0,09080236 ! female meiosis GO:0007143 7 5 0,000 0,01041623 0,09047456 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01041623 0,09014911 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01041623 0,089826 ! cobalt ion transport GO:0006824 11 5 0,000 0,01041623 0,08950519 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01041623 0,08918666 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01041623 0,0888704 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01041623 0,08855637 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01041623 0,08824455 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01041623 0,08793492 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01041623 0,08762746 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01041623 0,08732213 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01041623 0,08701893 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01041623 0,08671783 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01041623 0,0864188 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01041623 0,08612183 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01041623 0,08582689 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01041623 0,08553397 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01041623 0,08524304 ! negative chemotaxis GO:0050919 14 5 0,000 0,01041623 0,08495408 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01041623 0,08466707 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01041623 0,084382 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01041623 0,08409883 ! behavioral response to pain GO:0048266 9 5 0,000 0,01041623 0,08381757 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01041623 0,08353818 ! Notch receptor processing GO:0007220 8 5 0,000 0,01041623 0,08326064 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01041623 0,08298494 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01041623 0,08271106 ! micturition GO:0060073 9 5 0,000 0,01041623 0,08243899 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01041623 0,0821687 ! copulation GO:0007620 9 5 0,000 0,01041623 0,08190017 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01041623 0,0816334 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01041623 0,08136835 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01041623 0,08110502 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01041623 0,0808434 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01041623 0,08058345 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01041623 0,08032517 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01041623 0,08006854 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01041623 0,07981354 ! grooming behavior GO:0007625 6 5 0,000 0,01041623 0,07956017 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01041623 0,07930839 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01041623 0,07905821 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01041623 0,0788096 ! response to protozoan GO:0001562 10 5 0,000 0,01041623 0,07856255 ! lymph vessel development GO:0001945 10 5 0,000 0,01041623 0,07831704 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01041623 0,07807306 ! endochondral ossification GO:0001958 16 5 0,000 0,01041623 0,0778306 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01041623 0,07758964 ! parathyroid gland development GO:0060017 13 5 0,000 0,01041623 0,07735016 ! anagen GO:0042640 6 5 0,000 0,01041623 0,07711216 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01041623 0,07687562 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01041623 0,07664053 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01041623 0,07640687 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01041623 0,07617463 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01041623 0,0759438 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01041623 0,07571436 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01041623 0,0754863 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01041623 0,07525962 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01041623 0,07503429 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01041623 0,07481031 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01041623 0,07458766 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01041623 0,07436633 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01041623 0,07414631 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01041623 0,07392759 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01041623 0,07371015 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01041623 0,073494 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01041623 0,0732791 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01041623 0,07306546 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01041623 0,07285306 ! histidine catabolic process GO:0006548 6 5 0,000 0,01041623 0,07264189 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01041623 0,07243194 ! microvillus organization GO:0032528 7 5 0,000 0,01041623 0,07222321 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01041623 0,07201567 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01041623 0,07180932 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01041623 0,07160415 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01041623 0,07140015 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01041623 0,07119731 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01041623 0,07099562 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01041623 0,07079506 ! polyol catabolic process GO:0046174 7 5 0,000 0,01041623 0,07059564 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01041623 0,07039734 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01041623 0,07020015 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01041623 0,07000406 ! muscle cell migration GO:0014812 8 5 0,000 0,01041623 0,06980906 ! mitochondrial fission GO:0000266 8 5 0,000 0,01041623 0,06961515 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01041623 0,06942231 ! mRNA transcription GO:0009299 9 5 0,000 0,01041623 0,06923053 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01041623 0,06903981 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01041623 0,06885014 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01041623 0,06866151 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01041623 0,06847391 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01041623 0,06828734 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01041623 0,06810177 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01041623 0,06791722 ! response to food GO:0032094 6 5 0,000 0,01041623 0,06773366 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01041623 0,06755109 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01041623 0,0673695 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01041623 0,06718888 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01041623 0,06700923 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01041623 0,06683054 ! forebrain neuron development GO:0021884 13 5 0,000 0,01041623 0,0666528 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01041623 0,066476 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01041623 0,06630014 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01041623 0,0661252 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01041623 0,06595119 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01041623 0,06577809 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01041623 0,0656059 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01041623 0,0654346 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01041623 0,0652642 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01041623 0,06509468 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01041623 0,06492604 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01041623 0,06475828 ! basic amino acid transport GO:0015802 11 5 0,000 0,01041623 0,06459137 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01041623 0,06442533 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01041623 0,06426013 ! depyrimidination GO:0045008 10 5 0,000 0,01041623 0,06409579 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01041623 0,06393228 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01041623 0,0637696 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01041623 0,06360775 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01041623 0,06344672 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01041623 0,0632865 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01041623 0,06312708 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01041623 0,06296847 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01041623 0,06281066 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01041623 0,06265363 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01041623 0,06249739 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01041623 0,06234192 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01041623 0,06218723 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01041623 0,0620333 ! response to arsenic GO:0046685 10 5 0,000 0,01041623 0,06188013 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01041623 0,06172772 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01041623 0,06157605 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01041623 0,06142513 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01041623 0,06127495 ! response to cadmium ion GO:0046686 7 5 0,000 0,01041623 0,06112549 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01041623 0,06097677 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01041623 0,06082877 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01041623 0,06068148 ! decidualization GO:0046697 11 5 0,000 0,01041623 0,06053491 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01041623 0,06038904 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01041623 0,06024388 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01041623 0,06009941 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01041623 0,05995563 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01041623 0,05981254 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01041623 0,05967013 ! neural tube patterning GO:0021532 7 5 0,000 0,01041623 0,05952839 ! embryonic cleavage GO:0040016 6 5 0,000 0,01041623 0,05938733 ! peroxisome fission GO:0016559 5 5 0,000 0,01041623 0,05924693 ! histone demethylation GO:0016577 10 5 0,000 0,01041623 0,0591072 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01041623 0,05896812 ! mitotic recombination GO:0006312 9 5 0,000 0,01041623 0,0588297 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01041623 0,05869193 ! metaphase plate congression GO:0051310 7 5 0,000 0,01041623 0,0585548 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01041623 0,0584183 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01041623 0,05828245 ! enteric nervous system development GO:0048484 8 5 0,000 0,01041623 0,05814722 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01041623 0,05801262 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01041623 0,05787864 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01041623 0,05774528 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01041623 0,05761253 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01041623 0,0574804 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01041623 0,05734886 ! plasminogen activation GO:0031639 5 5 0,000 0,01041623 0,05721793 ! B cell homeostasis GO:0001782 13 5 0,000 0,01041623 0,05708759 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01041623 0,05695785 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01041623 0,05682869 ! metaphase GO:0051323 8 5 0,000 0,01041623 0,05670012 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01041623 0,05657213 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01041623 0,05644471 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01041623 0,05631787 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01041623 0,0561916 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01041623 0,05606589 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01041623 0,05594074 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01041623 0,05581615 ! response to redox state GO:0051775 5 5 0,000 0,01041623 0,05569212 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01041623 0,05556863 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01041623 0,05544569 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01041623 0,05532329 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01041623 0,05520144 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01041623 0,05508012 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01041623 0,05495933 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01041623 0,05483906 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01041623 0,05471933 ! striatum development GO:0021756 9 5 0,000 0,01041623 0,05460011 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01041623 0,05448142 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01041623 0,05436324 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01041623 0,05424557 ! glial cell migration GO:0008347 11 5 0,000 0,01041623 0,05412841 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01041623 0,05401175 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01041623 0,0538956 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01041623 0,05377994 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01041623 0,05366478 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01041623 0,05355011 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01041623 0,05343593 ! neuroprotection GO:0043526 6 5 0,000 0,01041623 0,05332224 ! neural plate development GO:0001840 8 5 0,000 0,01041623 0,05320903 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01041623 0,0530963 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01041623 0,05298404 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01041623 0,05287226 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01041623 0,05276095 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01041623 0,05265011 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01041623 0,05253973 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01041623 0,05242982 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01041623 0,05232036 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01041623 0,05221136 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01041623 0,05210281 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01041623 0,05199471 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01041623 0,05188707 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01041623 0,05177986 ! drug metabolic process GO:0017144 6 5 0,000 0,01041623 0,0516731 ! stem cell division GO:0017145 11 5 0,000 0,01041623 0,05156677 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01041623 0,05146089 ! organ regeneration GO:0031100 7 5 0,000 0,01041623 0,05135544 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01041623 0,05125041 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01041623 0,05114582 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01041623 0,05104166 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01055875 0,05163488 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01055875 0,05153014 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01083354 0,05276416 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01111147 0,05400849 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01167673 0,05664155 ! protein oligomerization GO:0051259 139 78 1,000 0,01167673 0,05652759 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01196402 0,05780209 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01196402 0,05768625 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,01225441 0,05896822 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01248663 0,05996572 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01248663 0,05984627 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01248663 0,05972729 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01248663 0,05960878 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01248663 0,05949075 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01248663 0,05937317 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01248663 0,05925607 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01248663 0,05913942 ! sleep GO:0030431 13 6 0,000 0,01248663 0,05902323 ! response to oxygen radical GO:0000305 11 6 0,000 0,01248663 0,0589075 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01248663 0,05879222 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01248663 0,0586774 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01248663 0,05856301 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01248663 0,05844908 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01248663 0,05833559 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01248663 0,05822253 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01248663 0,05810992 ! forebrain regionalization GO:0021871 8 6 0,000 0,01248663 0,05799773 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01248663 0,05788599 ! male meiosis GO:0007140 7 6 0,000 0,01248663 0,05777467 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01248663 0,05766377 ! response to zinc ion GO:0010043 9 6 0,000 0,01248663 0,05755331 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01248663 0,05744326 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01248663 0,05733364 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01248663 0,05722443 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01248663 0,05711564 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01248663 0,05700726 ! malate metabolic process GO:0006108 11 6 0,000 0,01248663 0,05689929 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01248663 0,05679173 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01248663 0,05668458 ! protein refolding GO:0042026 15 6 0,000 0,01248663 0,05657783 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01248663 0,05647148 ! opsonization GO:0008228 8 6 0,000 0,01248663 0,05636553 ! mating behavior GO:0007617 7 6 0,000 0,01248663 0,05625997 ! neuron remodeling GO:0016322 15 6 0,000 0,01248663 0,05615482 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01248663 0,05605005 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01248663 0,05594567 ! equilibrioception GO:0050957 14 6 0,000 0,01248663 0,05584168 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01248663 0,05573808 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01248663 0,05563486 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01248663 0,05553203 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01248663 0,05542957 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01248663 0,05532749 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01248663 0,05522578 ! toxin metabolic process GO:0009404 11 6 0,000 0,01248663 0,05512445 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01248663 0,05502349 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01248663 0,0549229 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01248663 0,05482268 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01248663 0,05472282 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01248663 0,05462332 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01248663 0,05452419 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01248663 0,05442541 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01248663 0,05432699 ! thymic T cell selection GO:0045061 12 6 0,000 0,01248663 0,05422893 ! protein lipoylation GO:0009249 10 6 0,000 0,01248663 0,05413122 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01248663 0,05403386 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01248663 0,05393685 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01248663 0,05384019 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01248663 0,05374388 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01248663 0,0536479 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01248663 0,05355228 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01248663 0,05345699 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01248663 0,05336204 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01248663 0,05326742 ! hyperosmotic response GO:0006972 9 6 0,000 0,01248663 0,05317314 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01248663 0,0530792 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01248663 0,05298558 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01248663 0,0528923 ! urea metabolic process GO:0019627 7 6 0,000 0,01248663 0,05279934 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01248663 0,05270671 ! neutrophil activation GO:0042119 8 6 0,000 0,01248663 0,05261441 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01248663 0,05252242 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01248663 0,05243076 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01248663 0,05233942 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01248663 0,05224839 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01248663 0,05215768 ! neuron apoptosis GO:0051402 9 6 0,000 0,01248663 0,05206729 ! nucleoside salvage GO:0043174 9 6 0,000 0,01248663 0,05197721 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01248663 0,05188744 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01248663 0,05179798 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01248663 0,05170882 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01248663 0,05161998 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01248663 0,05153143 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01248663 0,0514432 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01248663 0,05135526 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01248663 0,05126762 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01248663 0,05118028 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01248663 0,05109324 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01248663 0,0510065 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01248663 0,05092004 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01248663 0,05083389 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01248663 0,05074802 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01248663 0,05066244 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01248663 0,05057715 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01248663 0,05049215 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01248663 0,05040743 ! neural nucleus development GO:0048857 14 6 0,000 0,01248663 0,05032299 ! response to UV-C GO:0010225 11 6 0,000 0,01248663 0,05023884 ! astrocyte development GO:0014002 15 6 0,000 0,01248663 0,05015497 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01248663 0,05007138 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01248663 0,04998806 ! interaction with symbiont GO:0051702 13 6 0,000 0,01248663 0,04990503 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01248663 0,04982227 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01248663 0,04973978 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01248663 0,04965756 ! response to copper ion GO:0046688 10 6 0,000 0,01248663 0,04957562 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01248663 0,04949395 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01248663 0,04941254 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01248663 0,04933141 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01248663 0,04925054 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01248663 0,04916993 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01248663 0,04908959 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01248663 0,0490095 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01248663 0,04892968 ! hair follicle maturation GO:0048820 7 6 0,000 0,01248663 0,04885012 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01248663 0,04877082 ! Schwann cell development GO:0014044 15 6 0,000 0,01248663 0,04869178 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01248663 0,04861299 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01248663 0,04853445 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01248663 0,04845617 ! subpallium development GO:0021544 10 6 0,000 0,01248663 0,04837814 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01248663 0,04830036 ! histone ubiquitination GO:0016574 8 6 0,000 0,01248663 0,04822284 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01248663 0,04814556 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01248663 0,04806852 ! G2 phase GO:0051319 16 6 0,000 0,01248663 0,04799174 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01248663 0,04791519 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01248663 0,0478389 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01248663 0,04776284 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01248663 0,04768703 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01248663 0,04761145 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01248663 0,04753612 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01248663 0,04746102 ! receptor internalization GO:0031623 10 6 0,000 0,01248663 0,04738616 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01248663 0,04731154 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01248663 0,04723715 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01248663 0,04716299 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01248663 0,04708907 ! protein deubiquitination GO:0016579 14 6 0,000 0,01248663 0,04701538 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01248663 0,04694192 ! protein destabilization GO:0031648 9 6 0,000 0,01248663 0,04686868 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01248663 0,04679568 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01248663 0,0467229 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01248663 0,04665035 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01248663 0,04657803 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01248663 0,04650592 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01248663 0,04643404 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01248663 0,04636239 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01248663 0,04629095 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01248663 0,04621973 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01248663 0,04614873 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01248663 0,04607795 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01248663 0,04600739 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01248663 0,04593704 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01248663 0,04586691 ! catecholamine transport GO:0051937 9 6 0,000 0,01248663 0,04579699 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01248663 0,04572729 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01248663 0,04565779 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01248663 0,04558851 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01248663 0,04551943 ! maternal placenta development GO:0001893 12 6 0,000 0,01248663 0,04545057 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01248663 0,04538191 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01248663 0,04531346 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01248663 0,04524522 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01248663 0,04517718 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01248663 0,04510935 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01248663 0,04504172 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01254788 0,04519489 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01254788 0,04512734 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,01284441 0,04612484 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,01284441 0,0460561 ! response to oxygen levels GO:0070482 176 83 1,000 0,01314399 0,04706017 ! regulation of lyase activity GO:0051339 160 83 1,000 0,01314399 0,04699024 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,01344661 0,04800079 ! negative regulation of transport GO:0051051 153 84 1,000 0,01344661 0,04792968 ! negative regulation of growth GO:0045926 155 84 1,000 0,01344661 0,04785878 ! mitochondrion organization GO:0007005 148 86 1,000 0,0140609 0,04997124 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,01437255 0,05100348 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,01437255 0,05092836 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 14 7 0,000 0,01455276 0,05149109 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01455276 0,05141548 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01455276 0,05134009 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01455276 0,05126492 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01455276 0,05118998 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01455276 0,05111525 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01455276 0,05104073 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01455276 0,05096644 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01455276 0,05089236 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01455276 0,0508185 ! prostate gland development GO:0030850 13 7 0,000 0,01455276 0,05074485 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01455276 0,05067141 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01455276 0,05059818 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01455276 0,05052517 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01455276 0,05045237 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01455276 0,05037977 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01455276 0,05030739 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01455276 0,05023521 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01455276 0,05016324 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01455276 0,05009148 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01455276 0,05001992 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01455276 0,04994856 ! glycolipid transport GO:0046836 10 7 0,000 0,01455276 0,04987741 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01455276 0,04980646 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01455276 0,04973572 ! neuron adhesion GO:0007158 12 7 0,000 0,01455276 0,04966517 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01455276 0,04959482 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01455276 0,04952467 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01455276 0,04945472 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01455276 0,04938497 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01455276 0,04931541 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01455276 0,04924605 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01455276 0,04917689 ! mRNA stabilization GO:0048255 18 7 0,000 0,01455276 0,04910791 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01455276 0,04903914 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01455276 0,04897055 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01455276 0,04890216 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01455276 0,04883395 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01455276 0,04876594 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01455276 0,04869811 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01455276 0,04863048 ! lipoprotein transport GO:0042953 14 7 0,000 0,01455276 0,04856303 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01455276 0,04849577 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01455276 0,04842869 ! rhythmic behavior GO:0007622 15 7 0,000 0,01455276 0,0483618 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01455276 0,04829509 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01455276 0,04822857 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01455276 0,04816223 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01455276 0,04809608 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01455276 0,0480301 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01455276 0,04796431 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01455276 0,04789869 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01455276 0,04783326 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01455276 0,047768 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01455276 0,04770292 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01455276 0,04763802 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01455276 0,04757329 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01455276 0,04750874 ! spinal cord patterning GO:0021511 13 7 0,000 0,01455276 0,04744437 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01455276 0,04738017 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01455276 0,04731614 ! adrenal gland development GO:0030325 17 7 0,000 0,01455276 0,04725229 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01455276 0,0471886 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01455276 0,04712509 ! ovulation GO:0030728 9 7 0,000 0,01455276 0,04706175 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01455276 0,04699858 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01455276 0,04693558 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01455276 0,04687275 ! microtubule nucleation GO:0007020 20 7 0,000 0,01455276 0,04681008 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01455276 0,04674759 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01455276 0,04668526 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01455276 0,04662309 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01455276 0,04656109 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01455276 0,04649926 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01455276 0,04643759 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01455276 0,04637608 ! galactose metabolic process GO:0006012 13 7 0,000 0,01455276 0,04631474 ! vesicle fusion GO:0006906 17 7 0,000 0,01455276 0,04625356 ! response to dietary excess GO:0002021 8 7 0,000 0,01455276 0,04619254 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01455276 0,04613168 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01455276 0,04607098 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01455276 0,04601044 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01455276 0,04595006 ! organ growth GO:0035265 15 7 0,000 0,01455276 0,04588983 ! purine salvage GO:0043101 10 7 0,000 0,01455276 0,04582977 ! nucleoside transport GO:0015858 8 7 0,000 0,01455276 0,04576986 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01455276 0,04571011 ! parturition GO:0007567 14 7 0,000 0,01455276 0,04565051 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01455276 0,04559107 ! rRNA modification GO:0000154 14 7 0,000 0,01455276 0,04553179 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01455276 0,04547265 ! spindle checkpoint GO:0031577 15 7 0,000 0,01455276 0,04541367 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01455276 0,04535485 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01455276 0,04529618 ! macrophage differentiation GO:0030225 11 7 0,000 0,01455276 0,04523765 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01455276 0,04517928 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01455276 0,04512106 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01455276 0,04506299 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01455276 0,04500507 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01455276 0,0449473 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01455276 0,04488967 ! fibrinolysis GO:0042730 10 7 0,000 0,01455276 0,04483219 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01455276 0,04477486 ! eating behavior GO:0042755 7 7 0,000 0,01455276 0,04471768 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01455276 0,04466064 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01455276 0,04460375 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01455276 0,044547 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01455276 0,0444904 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01455276 0,04443394 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01455276 0,04437762 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01455276 0,04432145 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01455276 0,04426542 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01455276 0,04420952 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01455276 0,04415377 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01455276 0,04409817 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01455276 0,0440427 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01455276 0,04398737 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01455276 0,04393217 ! regulation of meiosis GO:0040020 12 7 0,000 0,01455276 0,04387712 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01455276 0,04382221 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01455276 0,04376743 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01455276 0,04371279 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01455276 0,04365828 ! transcription termination GO:0006353 13 7 0,000 0,01455276 0,04360391 ! response to tumor cell GO:0002347 13 7 0,000 0,01455276 0,04354968 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01455276 0,04349558 ! anaphase GO:0051322 17 7 0,000 0,01455276 0,04344162 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01455276 0,04338779 ! axonal fasciculation GO:0007413 18 7 0,000 0,01455276 0,04333409 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01455276 0,04328052 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01455276 0,04322709 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01455276 0,04317379 ! diuresis GO:0030146 12 7 0,000 0,01455276 0,04312062 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01455276 0,04306758 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01455276 0,04301467 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01455276 0,04296189 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01455276 0,04290924 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01455276 0,04285672 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01455276 0,04280433 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01455276 0,04275207 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01455276 0,04269993 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01455276 0,04264792 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01455276 0,04259604 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01455276 0,04254428 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01455276 0,04249265 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01455276 0,04244114 ! lymph node development GO:0048535 10 7 0,000 0,01455276 0,04238976 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01455276 0,0423385 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01455276 0,04228737 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01455276 0,04223636 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01455276 0,04218547 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01455276 0,04213471 ! adult feeding behavior GO:0008343 9 7 0,000 0,01455276 0,04208407 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01455276 0,04203355 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01455276 0,04198315 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01455276 0,04193287 ! muscle adaptation GO:0043500 14 7 0,000 0,01455276 0,04188271 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01455276 0,04183267 ! retina homeostasis GO:0001895 12 7 0,000 0,01455276 0,04178275 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01455276 0,04173295 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01455276 0,04168327 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01455276 0,0416337 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01455276 0,04158426 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01455276 0,04153493 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01455276 0,04148571 ! gland development GO:0048732 206 88 1,000 0,01468719 0,04181937 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01500479 0,04267319 ! ossification GO:0001503 188 90 1,000 0,01532535 0,0435334 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,01532535 0,04348206 ! bone development GO:0060348 189 91 1,000 0,01564885 0,04434763 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,01564885 0,04429546 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,01630464 0,04609748 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01630464 0,04604337 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01630464 0,04598939 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01661464 0,04680893 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01661464 0,04675418 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01661464 0,04669956 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01661464 0,04664507 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01661464 0,0465907 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01661464 0,04653647 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01661464 0,04648235 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01661464 0,04642837 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01661464 0,04637451 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01661464 0,04632077 ! meiotic prophase I GO:0007128 13 8 0,000 0,01661464 0,04626716 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01661464 0,04621367 ! oligopeptide transport GO:0006857 15 8 0,000 0,01661464 0,04616031 ! UTP metabolic process GO:0046051 8 8 0,000 0,01661464 0,04610706 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01661464 0,04605394 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01661464 0,04600095 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01661464 0,04594807 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01661464 0,04589532 ! succinate metabolic process GO:0006105 14 8 0,000 0,01661464 0,04584269 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01661464 0,04579018 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01661464 0,04573779 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01661464 0,04568551 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01661464 0,04563336 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01661464 0,04558133 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01661464 0,04552941 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01661464 0,04547762 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01661464 0,04542594 ! reflex GO:0060004 16 8 0,000 0,01661464 0,04537437 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01661464 0,04532293 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01661464 0,0452716 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01661464 0,04522039 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01661464 0,04516929 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01661464 0,04511831 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01661464 0,04506745 ! pigment granule organization GO:0048753 16 8 0,000 0,01661464 0,04501669 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01661464 0,04496606 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01661464 0,04491553 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01661464 0,04486512 ! histidine metabolic process GO:0006547 16 8 0,000 0,01661464 0,04481483 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01661464 0,04476464 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01661464 0,04471457 ! glycine catabolic process GO:0006546 13 8 0,000 0,01661464 0,04466461 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01661464 0,04461476 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01661464 0,04456502 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01661464 0,04451539 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01661464 0,04446588 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01661464 0,04441647 ! melanin metabolic process GO:0006582 15 8 0,000 0,01661464 0,04436717 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01661464 0,04431799 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01661464 0,04426891 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01661464 0,04421994 ! macrophage activation GO:0042116 12 8 0,000 0,01661464 0,04417108 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01661464 0,04412232 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01661464 0,04407368 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01661464 0,04402514 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01661464 0,0439767 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01661464 0,04392838 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01661464 0,04388016 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01661464 0,04383204 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01661464 0,04378404 ! osteoblast development GO:0002076 16 8 0,000 0,01661464 0,04373613 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01661464 0,04368833 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01661464 0,04364064 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01661464 0,04359305 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01661464 0,04354556 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01661464 0,04349818 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01661464 0,0434509 ! response to UV-B GO:0010224 16 8 0,000 0,01661464 0,04340372 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01661464 0,04335664 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01661464 0,04330967 ! intermediate filament organization GO:0045109 12 8 0,000 0,01661464 0,0432628 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01661464 0,04321603 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01661464 0,04316936 ! cellular extravasation GO:0045123 12 8 0,000 0,01661464 0,04312279 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01661464 0,04307632 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01661464 0,04302995 ! response to antibiotic GO:0046677 11 8 0,000 0,01661464 0,04298368 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01661464 0,04293751 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01661464 0,04289144 ! DNA topological change GO:0006265 12 8 0,000 0,01661464 0,04284547 ! response to tropane GO:0014073 15 8 0,000 0,01661464 0,0427996 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01661464 0,04275382 ! melanosome transport GO:0032402 13 8 0,000 0,01661464 0,04270815 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01661464 0,04266257 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01661464 0,04261708 ! mast cell activation GO:0045576 14 8 0,000 0,01661464 0,0425717 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01661464 0,04252641 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01661464 0,04248122 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01661464 0,04243612 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01661464 0,04239112 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01661464 0,04234621 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01661464 0,0423014 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01661464 0,04225669 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01661464 0,04221206 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01661464 0,04216754 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01661464 0,0421231 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01661464 0,04207876 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01661464 0,04203452 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01661464 0,04199036 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01661464 0,0419463 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01661464 0,04190233 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01661464 0,04185845 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01661464 0,04181467 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01661464 0,04177098 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01661464 0,04172737 ! hormone catabolic process GO:0042447 17 8 0,000 0,01661464 0,04168386 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01661464 0,04164044 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01661464 0,04159711 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01661464 0,04155387 ! ATP catabolic process GO:0006200 11 8 0,000 0,01661464 0,04151072 ! blastocyst growth GO:0001832 19 8 0,000 0,01661464 0,04146766 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01661464 0,04142469 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01661464 0,04138181 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01661464 0,04133901 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01661464 0,04129631 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01661464 0,04125369 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01661464 0,04121116 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01661464 0,04116872 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01661464 0,04112636 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01661464 0,04108409 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01661464 0,04104191 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01661464 0,04099982 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01661464 0,04095781 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01661464 0,04091589 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01661464 0,04087405 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01661464 0,0408323 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01661464 0,04079064 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01661464 0,04074906 ! regulation of T cell activation GO:0050863 158 94 1,000 0,01663689 0,04076207 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01697203 0,04154091 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,01697203 0,04149869 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01765094 0,04311488 ! regulation of protein localization GO:0032880 176 97 1,000 0,01765094 0,04307115 ! interphase GO:0051325 213 98 1,000 0,01799467 0,04386544 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,01834125 0,04466502 ! axon extension GO:0048675 15 9 0,000 0,01867227 0,04542517 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01867227 0,04537928 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01867227 0,04533349 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01867227 0,04528779 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01867227 0,04524218 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01867227 0,04519667 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01867227 0,04515125 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01867227 0,04510591 ! phosphate transport GO:0006817 19 9 0,000 0,01867227 0,04506067 ! reproductive behavior GO:0019098 19 9 0,000 0,01867227 0,04501552 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01867227 0,04497046 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01867227 0,04492549 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01867227 0,04488061 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01867227 0,04483582 ! GTP metabolic process GO:0046039 9 9 0,000 0,01867227 0,04479112 ! RNA methylation GO:0001510 15 9 0,000 0,01867227 0,0447465 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01867227 0,04470198 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01867227 0,04465754 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01867227 0,0446132 ! artery development GO:0060840 24 9 0,000 0,01867227 0,04456894 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01867227 0,04452477 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01867227 0,04448068 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01867227 0,04443669 ! chemosensory behavior GO:0007635 20 9 0,000 0,01867227 0,04439278 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01867227 0,04434895 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01867227 0,04430522 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01867227 0,04426157 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01867227 0,044218 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01867227 0,04417452 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01867227 0,04413113 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01867227 0,04408782 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01867227 0,0440446 ! protein targeting to ER GO:0045047 22 9 0,000 0,01867227 0,04400146 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01867227 0,0439584 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01867227 0,04391543 ! T cell selection GO:0045058 23 9 0,000 0,01867227 0,04387255 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01867227 0,04382975 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01867227 0,04378703 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01867227 0,04374439 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01867227 0,04370184 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01867227 0,04365937 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01867227 0,04361698 ! mannose metabolic process GO:0006013 13 9 0,000 0,01867227 0,04357467 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01867227 0,04353245 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01867227 0,04349031 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01867227 0,04344825 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01867227 0,04340627 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01867227 0,04336437 ! ruffle organization GO:0031529 15 9 0,000 0,01867227 0,04332256 ! retinol metabolic process GO:0042572 18 9 0,000 0,01867227 0,04328082 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01867227 0,04323916 ! behavioral fear response GO:0001662 22 9 0,000 0,01867227 0,04319759 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01867227 0,04315609 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01867227 0,04311467 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01867227 0,04307334 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,01867227 0,04303208 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01867227 0,0429909 ! segment specification GO:0007379 13 9 0,000 0,01867227 0,0429498 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01867227 0,04290878 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01867227 0,04286783 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01867227 0,04282697 ! response to amine stimulus GO:0014075 13 9 0,000 0,01867227 0,04278618 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01867227 0,04274547 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01867227 0,04270484 ! erythrocyte development GO:0048821 15 9 0,000 0,01867227 0,04266428 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01867227 0,0426238 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01867227 0,0425834 ! renal water homeostasis GO:0003091 14 9 0,000 0,01867227 0,04254308 ! postreplication repair GO:0006301 22 9 0,000 0,01867227 0,04250283 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01867227 0,04246266 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01867227 0,04242256 ! icosanoid secretion GO:0032309 15 9 0,000 0,01867227 0,04238254 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01867227 0,04234259 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01867227 0,04230272 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01867227 0,04226293 ! regulation of cell division GO:0051302 15 9 0,000 0,01867227 0,0422232 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01867227 0,04218356 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01867227 0,04214399 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01867227 0,04210449 ! sterol catabolic process GO:0016127 11 9 0,000 0,01867227 0,04206507 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01867227 0,04202572 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01867227 0,04198644 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01867227 0,04194724 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01867227 0,04190811 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01867227 0,04186905 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01867227 0,04183006 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01867227 0,04179115 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01867227 0,04175231 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01867227 0,04171355 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01867227 0,04167485 ! purine base metabolic process GO:0006144 21 9 0,000 0,01867227 0,04163623 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01867227 0,04159768 ! pigment granule transport GO:0051904 17 9 0,000 0,01867227 0,04155919 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01867227 0,04152079 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01867227 0,04148245 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01867227 0,04144418 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01867227 0,04140598 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01867227 0,04136785 ! mitochondrion localization GO:0051646 15 9 0,000 0,01867227 0,0413298 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02072567 0,04583268 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02072567 0,0457906 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02072567 0,04574859 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02072567 0,04570665 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02072567 0,0456648 ! synapsis GO:0007129 13 10 0,000 0,02072567 0,04562302 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02072567 0,04558132 ! N-glycan processing GO:0006491 20 10 0,000 0,02072567 0,04553969 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02072567 0,04549814 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02072567 0,04545666 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02072567 0,04541526 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02072567 0,04537394 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02072567 0,04533269 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02072567 0,04529152 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02072567 0,04525042 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02072567 0,04520939 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02072567 0,04516844 ! androgen metabolic process GO:0008209 17 10 0,000 0,02072567 0,04512757 ! phospholipid efflux GO:0033700 16 10 0,000 0,02072567 0,04508676 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02072567 0,04504603 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02072567 0,04500538 ! pathogenesis GO:0009405 13 10 0,000 0,02072567 0,0449648 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02072567 0,04492429 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02072567 0,04488385 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02072567 0,04484349 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02072567 0,0448032 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02072567 0,04476298 ! endoderm development GO:0007492 16 10 0,000 0,02072567 0,04472283 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02072567 0,04468276 ! arginine catabolic process GO:0006527 13 10 0,000 0,02072567 0,04464276 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02072567 0,04460283 ! proline metabolic process GO:0006560 13 10 0,000 0,02072567 0,04456297 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02072567 0,04452318 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02072567 0,04448346 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02072567 0,04444381 ! V(D)J recombination GO:0033151 28 10 0,000 0,02072567 0,04440424 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02072567 0,04436473 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02072567 0,0443253 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02072567 0,04428593 ! B cell proliferation GO:0042100 18 10 0,000 0,02072567 0,04424664 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02072567 0,04420741 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02072567 0,04416826 ! multicellular organism growth GO:0035264 18 10 0,000 0,02072567 0,04412917 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02072567 0,04409015 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02072567 0,0440512 ! epithelial cell development GO:0002064 20 10 0,000 0,02072567 0,04401232 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02072567 0,04397351 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02072567 0,04393477 ! macroautophagy GO:0016236 17 10 0,000 0,02072567 0,04389609 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02072567 0,04385748 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02072567 0,04381895 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02072567 0,04378047 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02072567 0,04374207 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02072567 0,04370373 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02072567 0,04366546 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02072567 0,04362726 ! brain morphogenesis GO:0048854 23 10 0,000 0,02072567 0,04358913 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02072567 0,04355106 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02072567 0,04351305 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02072567 0,04347512 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02072567 0,04343725 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02072567 0,04339944 ! response to dsRNA GO:0043331 20 10 0,000 0,02072567 0,0433617 ! DNA ligation GO:0006266 19 10 0,000 0,02072567 0,04332403 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02072567 0,04328642 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02072567 0,04324888 ! melanosome localization GO:0032400 16 10 0,000 0,02072567 0,0432114 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02072567 0,04317399 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02072567 0,04313664 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02072567 0,04309936 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02072567 0,04306214 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02072567 0,04302499 ! mRNA cleavage GO:0006379 17 10 0,000 0,02072567 0,0429879 ! protein sumoylation GO:0016925 15 10 0,000 0,02072567 0,04295087 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02072567 0,04291391 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02072567 0,04287701 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02072567 0,04284017 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02072567 0,0428034 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02072567 0,04276669 ! salivary gland development GO:0007431 27 10 0,000 0,02072567 0,04273004 ! prophase GO:0051324 15 10 0,000 0,02072567 0,04269346 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02072567 0,04265694 ! apical protein localization GO:0045176 15 10 0,000 0,02072567 0,04262048 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02072567 0,04258408 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02072567 0,04254775 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02072567 0,04251148 ! midbrain development GO:0030901 13 10 0,000 0,02072567 0,04247526 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02072567 0,04243912 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02072567 0,04240303 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02072567 0,042367 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02072567 0,04233104 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02072567 0,04229513 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02072567 0,04225929 ! detection of calcium ion GO:0005513 23 10 0,000 0,02072567 0,04222351 ! oocyte development GO:0048599 17 10 0,000 0,02072567 0,04218778 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02072567 0,04215212 ! blastocyst formation GO:0001825 17 10 0,000 0,02072567 0,04211652 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02072567 0,04208098 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02072567 0,0420455 ! activation of innate immune response GO:0002218 12 10 0,000 0,02072567 0,04201008 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02072567 0,04197471 ! response to nicotine GO:0035094 20 10 0,000 0,02072567 0,04193941 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02072567 0,04190417 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02072567 0,04186898 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02072567 0,04183386 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02277484 0,04593148 ! respiratory burst GO:0045730 17 11 0,000 0,02277484 0,04589301 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02277484 0,04585461 ! neuron fate specification GO:0048665 17 11 0,000 0,02277484 0,04581627 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02277484 0,04577799 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02277484 0,04573978 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02277484 0,04570163 ! thyroid gland development GO:0030878 26 11 0,000 0,02277484 0,04566355 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02277484 0,04562553 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02277484 0,04558757 ! response to pain GO:0048265 24 11 0,000 0,02277484 0,04554967 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02277484 0,04551184 ! T cell proliferation GO:0042098 26 11 0,000 0,02277484 0,04547407 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02277484 0,04543637 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02277484 0,04539872 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02277484 0,04536114 ! bone resorption GO:0045453 16 11 0,000 0,02277484 0,04532362 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02277484 0,04528616 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02277484 0,04524877 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02277484 0,04521143 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02277484 0,04517416 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02277484 0,04513695 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02277484 0,0450998 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02277484 0,04506271 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02277484 0,04502568 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02277484 0,04498872 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02277484 0,04495181 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02277484 0,04491496 ! lipid digestion GO:0044241 18 11 0,000 0,02277484 0,04487818 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02277484 0,04484145 ! UV protection GO:0009650 19 11 0,000 0,02277484 0,04480479 ! adult heart development GO:0007512 14 11 0,000 0,02277484 0,04476818 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02277484 0,04473164 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02277484 0,04469515 ! temperature homeostasis GO:0001659 17 11 0,000 0,02277484 0,04465873 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02277484 0,04462236 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02277484 0,04458605 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02277484 0,0445498 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02277484 0,04451361 ! regulation of organ growth GO:0046620 13 11 0,000 0,02277484 0,04447748 ! pigment granule localization GO:0051875 20 11 0,000 0,02277484 0,04444141 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02277484 0,04440539 ! vasoconstriction GO:0042310 18 11 0,000 0,02277484 0,04436944 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02277484 0,04433354 ! embryonic axis specification GO:0000578 18 11 0,000 0,02277484 0,0442977 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02277484 0,04426192 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02277484 0,0442262 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02277484 0,04419053 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02277484 0,04415492 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02277484 0,04411937 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02277484 0,04408388 ! zymogen activation GO:0031638 15 11 0,000 0,02277484 0,04404844 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02277484 0,04401306 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02277484 0,04397773 ! nucleosome positioning GO:0016584 15 11 0,000 0,02277484 0,04394247 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02277484 0,04390726 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02277484 0,0438721 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02277484 0,04383701 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02277484 0,04380196 ! acid secretion GO:0046717 18 11 0,000 0,02277484 0,04376698 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02277484 0,04373205 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02277484 0,04369717 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02277484 0,04366236 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02277484 0,04362759 ! oocyte differentiation GO:0009994 18 11 0,000 0,02277484 0,04359289 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02277484 0,04355823 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02277484 0,04352364 ! cholesterol efflux GO:0033344 19 11 0,000 0,02277484 0,04348909 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02277484 0,04345461 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02277484 0,04342017 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02277484 0,04338579 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02277484 0,04335147 ! embryonic gut development GO:0048566 15 11 0,000 0,02277484 0,0433172 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02277484 0,04328298 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02277484 0,04324882 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02277484 0,04321471 ! defense response to fungus GO:0050832 13 11 0,000 0,02277484 0,04318066 ! developmental induction GO:0031128 19 11 0,000 0,02277484 0,04314666 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02277484 0,04311271 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02277484 0,04307882 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02277484 0,04304498 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02277484 0,04301119 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02277484 0,04297746 ! nucleus localization GO:0051647 19 11 0,000 0,02277484 0,04294378 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02277484 0,04291015 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02481978 0,04672645 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02481978 0,04668991 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02481978 0,04665344 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02481978 0,04661702 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02481978 0,04658066 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02481978 0,04654435 ! cartilage condensation GO:0001502 20 12 0,000 0,02481978 0,0465081 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02481978 0,04647191 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02481978 0,04643577 ! protein complex disassembly GO:0043241 27 12 0,000 0,02481978 0,04639969 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02481978 0,04636367 ! hippocampus development GO:0021766 26 12 0,000 0,02481978 0,0463277 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02481978 0,04629178 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02481978 0,04625593 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02481978 0,04622012 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02481978 0,04618438 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02481978 0,04614869 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02481978 0,04611305 ! drug transport GO:0015893 16 12 0,000 0,02481978 0,04607747 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02481978 0,04604194 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02481978 0,04600647 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02481978 0,04597106 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02481978 0,04593569 ! focal adhesion formation GO:0048041 35 12 0,000 0,02481978 0,04590038 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02481978 0,04586513 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02481978 0,04582993 ! forebrain cell migration GO:0021885 21 12 0,000 0,02481978 0,04579479 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02481978 0,04575969 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02481978 0,04572466 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02481978 0,04568967 ! entry into host cell GO:0030260 32 12 0,000 0,02481978 0,04565474 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02481978 0,04561986 ! monoamine transport GO:0015844 18 12 0,000 0,02481978 0,04558504 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02481978 0,04555027 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02481978 0,04551555 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02481978 0,04548088 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02481978 0,04544627 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02481978 0,04541171 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02481978 0,0453772 ! protein homotetramerization GO:0051289 21 12 0,000 0,02481978 0,04534275 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02481978 0,04530835 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02481978 0,045274 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02481978 0,0452397 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02481978 0,04520545 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02481978 0,04517126 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02481978 0,04513711 ! cranial nerve development GO:0021545 20 12 0,000 0,02481978 0,04510302 ! fucose catabolic process GO:0019317 22 12 0,000 0,02481978 0,04506898 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02481978 0,04503499 ! histone acetylation GO:0016573 26 12 0,000 0,02481978 0,04500106 ! histone methylation GO:0016571 26 12 0,000 0,02481978 0,04496717 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02481978 0,04493333 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02481978 0,04489955 ! gland morphogenesis GO:0022612 29 12 0,000 0,02481978 0,04486582 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02481978 0,04483213 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02481978 0,0447985 ! T cell homeostasis GO:0043029 25 12 0,000 0,02481978 0,04476492 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02481978 0,04473139 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02481978 0,0446979 ! spleen development GO:0048536 22 12 0,000 0,02481978 0,04466447 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02481978 0,04463109 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02481978 0,04459776 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02481978 0,04456448 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02481978 0,04453125 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02481978 0,04449806 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02481978 0,04446493 ! response to cold GO:0009409 17 12 0,000 0,02481978 0,04443185 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02481978 0,04439881 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02481978 0,04436583 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02686052 0,04797803 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02686052 0,04794244 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02686052 0,0479069 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02686052 0,04787142 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02686052 0,04783598 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02686052 0,0478006 ! lipid localization GO:0010876 28 13 0,000 0,02686052 0,04776527 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02686052 0,04772999 ! organelle fusion GO:0048284 32 13 0,000 0,02686052 0,04769477 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02686052 0,0476596 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02686052 0,04762447 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02686052 0,0475894 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02686052 0,04755439 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02686052 0,04751942 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02686052 0,0474845 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02686052 0,04744964 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02686052 0,04741483 ! methionine metabolic process GO:0006555 27 13 0,000 0,02686052 0,04738007 ! plasma membrane organization GO:0007009 24 13 0,000 0,02686052 0,04734536 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02686052 0,0473107 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02686052 0,04727609 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02686052 0,04724153 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02686052 0,04720702 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02686052 0,04717256 ! response to X-ray GO:0010165 25 13 0,000 0,02686052 0,04713816 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02686052 0,0471038 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02686052 0,04706949 ! exocrine system development GO:0035272 32 13 0,000 0,02686052 0,04703523 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02686052 0,04700103 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02686052 0,04696687 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02686052 0,04693276 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02686052 0,0468987 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02686052 0,04686469 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02686052 0,04683073 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02686052 0,04679682 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02686052 0,04676296 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02686052 0,04672915 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02686052 0,04669538 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02686052 0,04666167 ! ribosome assembly GO:0042255 17 13 0,000 0,02686052 0,046628 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02686052 0,04659438 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02686052 0,04656081 ! chromatin silencing GO:0006342 26 13 0,000 0,02686052 0,04652729 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02686052 0,04649382 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02686052 0,0464604 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02686052 0,04642702 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02686052 0,04639369 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02686052 0,04636041 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02686052 0,04632718 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02686052 0,04629399 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02686052 0,04626085 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02686052 0,04622776 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02686052 0,04619472 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02686052 0,04616172 ! embryonic placenta development GO:0001892 23 13 0,000 0,02686052 0,04612877 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02686052 0,04609587 ! insulin secretion GO:0030073 23 13 0,000 0,02686052 0,04606302 ! actin filament polymerization GO:0030041 24 13 0,000 0,02686052 0,04603021 ! acrosome reaction GO:0007340 18 13 0,000 0,02686052 0,04599745 ! rRNA transcription GO:0009303 25 14 0,000 0,02889705 0,04944972 ! lactation GO:0007595 26 14 0,000 0,02889705 0,04941458 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02889705 0,04937948 ! reproductive cellular process GO:0048610 20 14 0,000 0,02889705 0,04934444 ! tRNA modification GO:0006400 20 14 0,000 0,02889705 0,04930944 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02889705 0,04927449 ! regulation of S phase GO:0033261 23 14 0,000 0,02889705 0,0492396 ! water transport GO:0006833 21 14 0,000 0,02889705 0,04920475 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02889705 0,04916995 ! non-recombinational repair GO:0000726 25 14 0,000 0,02889705 0,0491352 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02889705 0,0491005 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02889705 0,04906585 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02889705 0,04903125 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02889705 0,04899669 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02889705 0,04896219 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02889705 0,04892773 ! palate development GO:0060021 31 14 0,000 0,02889705 0,04889333 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02889705 0,04885897 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02889705 0,04882466 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02889705 0,04879039 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02889705 0,04875618 ! arginine metabolic process GO:0006525 17 14 0,000 0,02889705 0,04872201 ! regulation of heart rate GO:0002027 24 14 0,000 0,02889705 0,04868789 ! organic alcohol transport GO:0015850 29 14 0,000 0,02889705 0,04865382 ! embryo implantation GO:0007566 30 14 0,000 0,02889705 0,0486198 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02889705 0,04858582 ! L-amino acid transport GO:0015807 30 14 0,000 0,02889705 0,04855189 ! bone mineralization GO:0030282 17 14 0,000 0,02889705 0,04851801 ! stem cell development GO:0048864 43 14 0,000 0,02889705 0,04848418 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02889705 0,04845039 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02889705 0,04841665 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02889705 0,04838296 ! cerebellum development GO:0021549 21 14 0,000 0,02889705 0,04834931 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02889705 0,04831571 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02889705 0,04828216 ! response to gamma radiation GO:0010332 28 14 0,000 0,02889705 0,04824865 ! cofactor transport GO:0051181 26 14 0,000 0,02889705 0,04821519 ! NADP metabolic process GO:0006739 24 14 0,000 0,02889705 0,04818178 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02889705 0,04814841 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02889705 0,04811509 ! intestinal absorption GO:0050892 25 14 0,000 0,02889705 0,04808182 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02889705 0,04804859 ! oxygen transport GO:0015671 21 14 0,000 0,02889705 0,04801541 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02889705 0,04798227 ! male genitalia development GO:0030539 24 14 0,000 0,02889705 0,04794918 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02889705 0,04791613 ! regulation of axon extension GO:0030516 37 14 0,000 0,02889705 0,04788313 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02889705 0,04785018 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03092939 0,05118027 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03092939 0,0511451 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,03092939 0,05110997 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03092939 0,05107489 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03092939 0,05103986 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03092939 0,05100488 ! copper ion transport GO:0006825 20 15 0,000 0,03092939 0,05096994 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03092939 0,05093506 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03092939 0,05090022 ! sulfate transport GO:0008272 23 15 0,000 0,03092939 0,05086542 ! response to cAMP GO:0051591 22 15 0,000 0,03092939 0,05083068 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03092939 0,05079598 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03092939 0,05076133 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03092939 0,05072673 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03092939 0,05069218 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03092939 0,05065767 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03092939 0,05062321 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03092939 0,05058879 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03092939 0,05055443 ! pituitary gland development GO:0021983 29 15 0,000 0,03092939 0,05052011 ! vesicle coating GO:0006901 33 15 0,000 0,03092939 0,05048583 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03092939 0,0504516 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03092939 0,05041742 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03092939 0,05038329 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03092939 0,0503492 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03092939 0,05031516 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03092939 0,05028116 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03092939 0,05024721 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03092939 0,0502133 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03092939 0,05017944 ! histone deacetylation GO:0016575 20 15 0,000 0,03092939 0,05014563 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03092939 0,05011186 ! tissue regeneration GO:0042246 26 15 0,000 0,03092939 0,05007814 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03092939 0,05004446 ! water homeostasis GO:0030104 27 15 0,000 0,03092939 0,05001083 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03092939 0,04997724 ! muscle maintenance GO:0046716 26 15 0,000 0,03092939 0,0499437 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03092939 0,04991021 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03092939 0,04987675 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03092939 0,04984335 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03092939 0,04980998 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03092939 0,04977667 ! detection of bacterium GO:0016045 18 15 0,000 0,03092939 0,04974339 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03092939 0,04971016 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03092939 0,04967698 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03092939 0,04964384 ! peptide hormone processing GO:0016486 23 15 0,000 0,03092939 0,04961074 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03295754 0,05282868 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03295754 0,05279351 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03295754 0,05275838 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03295754 0,05272331 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03295754 0,05268827 ! bone remodeling GO:0046849 27 16 0,000 0,03295754 0,05265329 ! filopodium assembly GO:0046847 32 16 0,000 0,03295754 0,05261835 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03295754 0,05258346 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03295754 0,05254861 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03295754 0,05251381 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03295754 0,05247905 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03295754 0,05244435 ! startle response GO:0001964 28 16 0,000 0,03295754 0,05240968 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03295754 0,05237507 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03295754 0,0523405 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03295754 0,05230597 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03295754 0,05227149 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03295754 0,05223706 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03295754 0,05220267 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03295754 0,05216832 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03295754 0,05213402 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03295754 0,05209977 ! response to osmotic stress GO:0006970 25 16 0,000 0,03295754 0,05206556 ! lysosomal transport GO:0007041 26 16 0,000 0,03295754 0,0520314 ! fructose metabolic process GO:0006000 25 16 0,000 0,03295754 0,05199728 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03295754 0,0519632 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03295754 0,05192918 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03295754 0,05189519 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03295754 0,05186125 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03295754 0,05182735 ! axon cargo transport GO:0008088 43 16 0,000 0,03295754 0,0517935 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03295754 0,05175969 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03295754 0,05172593 ! DNA replication initiation GO:0006270 27 16 0,000 0,03295754 0,05169221 ! neuron recognition GO:0008038 35 16 0,000 0,03295754 0,05165853 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03295754 0,0516249 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03295754 0,05159131 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03295754 0,05155777 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03295754 0,05152427 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03295754 0,05149081 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03295754 0,0514574 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03295754 0,05142403 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03295754 0,0513907 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03295754 0,05135742 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03295754 0,05132418 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03295754 0,05129098 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03295754 0,05125782 ! defense response to virus GO:0051607 37 16 0,000 0,03295754 0,05122471 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03498152 0,0543354 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03498152 0,05430035 ! metencephalon development GO:0022037 30 17 0,000 0,03498152 0,05426534 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03498152 0,05423037 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03498152 0,05419545 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03498152 0,05416058 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03498152 0,05412575 ! endothelial cell migration GO:0043542 28 17 0,000 0,03498152 0,05409096 ! inositol metabolic process GO:0006020 28 17 0,000 0,03498152 0,05405622 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03498152 0,05402152 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03498152 0,05398687 ! glial cell development GO:0021782 27 17 0,000 0,03498152 0,05395227 ! limbic system development GO:0021761 36 17 0,000 0,03498152 0,0539177 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03498152 0,05388318 ! adult walking behavior GO:0007628 33 17 0,000 0,03498152 0,05384871 ! heart looping GO:0001947 30 17 0,000 0,03498152 0,05381428 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03498152 0,05377989 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03498152 0,05374555 ! myoblast differentiation GO:0045445 45 17 0,000 0,03498152 0,05371125 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03498152 0,053677 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03498152 0,05364279 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03498152 0,05360862 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03498152 0,0535745 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03498152 0,05354042 ! glycine metabolic process GO:0006544 28 17 0,000 0,03498152 0,05350638 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03498152 0,05347239 ! NAD metabolic process GO:0019674 29 17 0,000 0,03498152 0,05343843 ! membrane budding GO:0006900 37 17 0,000 0,03498152 0,05340453 ! DNA integration GO:0015074 29 17 0,000 0,03498152 0,05337066 ! regulation of protein binding GO:0043393 33 17 0,000 0,03498152 0,05333684 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03498152 0,05330306 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03498152 0,05326933 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03498152 0,05323563 ! genitalia development GO:0048806 30 17 0,000 0,03498152 0,05320198 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03498152 0,05316837 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03498152 0,05313481 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03498152 0,05310128 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03498152 0,0530678 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03498152 0,05303436 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03498152 0,05300097 ! steroid catabolic process GO:0006706 31 17 0,000 0,03498152 0,05296761 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03498152 0,0529343 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03498152 0,05290103 ! gas transport GO:0015669 25 17 0,000 0,03498152 0,0528678 ! organic cation transport GO:0015695 31 17 0,000 0,03498152 0,05283461 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03498152 0,05280146 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03498152 0,05276836 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03498152 0,0527353 ! microspike assembly GO:0030035 36 17 0,000 0,03498152 0,05270228 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03498152 0,0526693 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03700133 0,05567554 ! neuron maturation GO:0042551 42 18 0,000 0,03700133 0,05564074 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03700133 0,05560599 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03700133 0,05557128 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03700133 0,05553661 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03700133 0,05550199 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03700133 0,05546741 ! memory GO:0007613 31 18 0,000 0,03700133 0,05543287 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03700133 0,05539837 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03700133 0,05536392 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03700133 0,05532951 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03700133 0,05529515 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03700133 0,05526082 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03700133 0,05522654 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03700133 0,05519231 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03700133 0,05515811 ! response to retinoic acid GO:0032526 26 18 0,000 0,03700133 0,05512396 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03700133 0,05508984 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03700133 0,05505578 ! response to fungus GO:0009620 21 18 0,000 0,03700133 0,05502175 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03700133 0,05498776 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03700133 0,05495382 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03700133 0,05491992 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03700133 0,05488606 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03700133 0,05485224 ! vitamin transport GO:0051180 27 18 0,000 0,03700133 0,05481847 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03700133 0,05478473 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03700133 0,05475104 ! nerve development GO:0021675 28 18 0,000 0,03700133 0,05471739 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03700133 0,05468378 ! protein secretion GO:0009306 39 19 0,000 0,03901697 0,05762728 ! positive regulation of translation GO:0045727 30 19 0,000 0,03901697 0,05759192 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03901697 0,05755661 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03901697 0,05752134 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03901697 0,05748612 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03901697 0,05745094 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03901697 0,0574158 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03901697 0,0573807 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03901697 0,05734565 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03901697 0,05731064 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03901697 0,05727568 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03901697 0,05724075 ! cerebral cortex development GO:0021987 36 19 0,000 0,03901697 0,05720587 ! pigmentation during development GO:0048066 41 19 0,000 0,03901697 0,05717103 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03901697 0,05713623 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03901697 0,05710148 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03901697 0,05706677 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03901697 0,0570321 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03901697 0,05699747 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03901697 0,05696288 ! peptide cross-linking GO:0018149 37 19 0,000 0,03901697 0,05692834 ! protein export from nucleus GO:0006611 36 19 0,000 0,03901697 0,05689384 ! heart process GO:0003015 30 19 0,000 0,03901697 0,05685938 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03901697 0,05682496 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03901697 0,05679058 ! visual learning GO:0008542 36 19 0,000 0,03901697 0,05675625 ! cellular pigmentation GO:0033059 36 19 0,000 0,03901697 0,05672195 ! G1 phase GO:0051318 40 19 0,000 0,03901697 0,0566877 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03901697 0,05665349 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03901697 0,05661932 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03901697 0,05658519 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03901697 0,0565511 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03901697 0,05651706 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03901697 0,05648305 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03901697 0,05644909 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03901697 0,05641516 ! cilium assembly GO:0042384 37 19 0,000 0,03901697 0,05638128 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03901697 0,05634744 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04102846 0,05921685 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04102846 0,05918135 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04102846 0,05914589 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04102846 0,05911047 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04102846 0,0590751 ! response to vitamin GO:0033273 31 20 0,000 0,04102846 0,05903976 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04102846 0,05900447 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04102846 0,05896923 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04102846 0,05893402 ! response to alkaloid GO:0043279 38 20 0,000 0,04102846 0,05889886 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04102846 0,05886374 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04102846 0,05882866 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04102846 0,05879362 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04102846 0,05875862 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04102846 0,05872367 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04102846 0,05868875 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04102846 0,05865388 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04102846 0,05861905 ! body fluid secretion GO:0007589 31 20 0,000 0,04102846 0,05858426 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04102846 0,05854952 ! peptide secretion GO:0002790 35 20 0,000 0,04102846 0,05851481 ! stem cell differentiation GO:0048863 53 20 0,000 0,04102846 0,05848015 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04102846 0,05844552 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04102846 0,05841094 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04102846 0,0583764 ! sensory perception of pain GO:0019233 30 20 0,000 0,04102846 0,05834189 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04102846 0,05830743 ! diencephalon development GO:0021536 34 20 0,000 0,04102846 0,05827301 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04102846 0,05823863 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04102846 0,0582043 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04102846 0,05817 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04102846 0,05813574 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04102846 0,05810152 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04102846 0,05806734 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04102846 0,05803321 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04102846 0,05799911 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04102846 0,05796505 ! regulation of glucose import GO:0046324 29 20 0,000 0,04102846 0,05793104 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04102846 0,05789706 ! actin filament-based movement GO:0030048 43 20 0,000 0,04102846 0,05786312 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04102846 0,05782922 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04102846 0,05779537 ! negative regulation of translation GO:0017148 29 20 0,000 0,04102846 0,05776155 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04102846 0,05772777 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04102846 0,05769403 ! regulation of cell killing GO:0031341 42 21 0,000 0,04303581 0,06048141 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04303581 0,0604461 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04303581 0,06041083 ! hormone secretion GO:0046879 38 21 0,000 0,04303581 0,06037561 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04303581 0,06034042 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04303581 0,06030528 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04303581 0,06027018 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04303581 0,06023512 ! axis specification GO:0009798 38 21 0,000 0,04303581 0,0602001 ! ovarian follicle development GO:0001541 35 21 0,000 0,04303581 0,06016512 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04303581 0,06013018 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04303581 0,06009528 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04303581 0,06006042 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04303581 0,0600256 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04303581 0,05999083 ! cell aging GO:0007569 44 21 0,000 0,04303581 0,05995609 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04303581 0,05992139 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04303581 0,05988674 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04303581 0,05985212 ! cytolysis GO:0019835 24 21 0,000 0,04303581 0,05981754 ! vasodilation GO:0042311 39 21 0,000 0,04303581 0,05978301 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04303581 0,05974851 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04303581 0,05971405 ! oogenesis GO:0048477 36 21 0,000 0,04303581 0,05967964 ! DNA modification GO:0006304 34 21 0,000 0,04303581 0,05964526 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04303581 0,05961092 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04303581 0,05957662 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04303581 0,05954236 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04303581 0,05950814 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04303581 0,05947396 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04303581 0,05943982 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04303581 0,05940572 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04303581 0,05937166 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04303581 0,05933763 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04303581 0,05930365 ! collagen catabolic process GO:0030574 28 21 0,000 0,04303581 0,0592697 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04303581 0,05923579 ! gut development GO:0048565 39 21 0,000 0,04303581 0,05920193 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04503903 0,06192223 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04503903 0,06188687 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04503903 0,06185154 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04503903 0,06181626 ! microtubule-based transport GO:0010970 54 22 0,000 0,04503903 0,06178102 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04503903 0,06174581 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04503903 0,06171065 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04503903 0,06167553 ! regeneration GO:0031099 41 22 0,000 0,04503903 0,06164045 ! keratinization GO:0031424 28 22 0,000 0,04503903 0,0616054 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04503903 0,0615704 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04503903 0,06153544 ! sensory perception of taste GO:0050909 28 22 0,000 0,04503903 0,06150051 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04503903 0,06146563 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04503903 0,06143078 ! vacuolar transport GO:0007034 36 22 0,000 0,04503903 0,06139598 ! lysosome organization GO:0007040 41 22 0,000 0,04503903 0,06136121 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04503903 0,06132649 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04503903 0,0612918 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04503903 0,06125715 ! fucose metabolic process GO:0006004 39 22 0,000 0,04503903 0,06122254 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04503903 0,06118797 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04503903 0,06115344 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04503903 0,06111895 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04503903 0,0610845 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04503903 0,06105009 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04503903 0,06101571 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04503903 0,06098137 ! sarcomere organization GO:0045214 30 22 0,000 0,04503903 0,06094708 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04503903 0,06091282 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04503903 0,0608786 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04503903 0,06084441 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04503903 0,06081027 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04503903 0,06077617 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04703812 0,06343818 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04703812 0,06340264 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04703812 0,06336714 ! gluconeogenesis GO:0006094 33 23 0,000 0,04703812 0,06333168 ! viral genome replication GO:0019079 41 23 0,000 0,04703812 0,06329626 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04703812 0,06326088 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04703812 0,06322553 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04703812 0,06319023 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04703812 0,06315497 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04703812 0,06311975 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04703812 0,06308456 ! visual behavior GO:0007632 42 23 0,000 0,04703812 0,06304942 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04703812 0,06301431 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04703812 0,06297925 ! response to ethanol GO:0045471 46 23 0,000 0,04703812 0,06294422 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04703812 0,06290923 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04703812 0,06287428 ! peroxisome organization GO:0007031 37 23 0,000 0,04703812 0,06283937 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04703812 0,0628045 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04703812 0,06276967 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04703812 0,06273487 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04703812 0,06270011 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04703812 0,0626654 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04703812 0,06263072 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04703812 0,06259608 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04703812 0,06256147 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04703812 0,06252691 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04703812 0,06249238 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04703812 0,0624579 ! fatty acid transport GO:0015908 44 23 0,000 0,04703812 0,06242345 ! platelet activation GO:0030168 37 23 0,000 0,04703812 0,06238903 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04703812 0,06235466 ! hormone transport GO:0009914 40 23 0,000 0,04703812 0,06232032 ! cell-cell recognition GO:0009988 25 23 0,000 0,04703812 0,06228603 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04703812 0,06225176 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04703812 0,06221754 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04703812 0,06218336 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04703812 0,06214921 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04903309 0,06474951 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04903309 0,06471399 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04903309 0,06467851 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04903309 0,06464307 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04903309 0,06460767 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04903309 0,06457231 ! vesicle docking GO:0048278 47 24 0,000 0,04903309 0,06453698 ! spinal cord development GO:0021510 47 24 0,000 0,04903309 0,0645017 ! vacuole organization GO:0007033 43 24 0,000 0,04903309 0,06446645 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04903309 0,06443124 ! digestive system process GO:0022600 39 24 0,000 0,04903309 0,06439607 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04903309 0,06436094 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04903309 0,06432585 ! regulation of behavior GO:0050795 43 24 0,000 0,04903309 0,06429079 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04903309 0,06425578 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04903309 0,0642208 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04903309 0,06418586 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04903309 0,06415095 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04903309 0,06411609 ! membrane depolarization GO:0051899 39 24 0,000 0,04903309 0,06408126 ! pallium development GO:0021543 49 24 0,000 0,04903309 0,06404647 ! pentose metabolic process GO:0019321 35 24 0,000 0,04903309 0,06401172 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04903309 0,06397701 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04903309 0,06394233 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04903309 0,06390769 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04903309 0,06387309 ! alditol metabolic process GO:0019400 38 24 0,000 0,04903309 0,06383853 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04903309 0,063804 ! regulation of amine transport GO:0051952 40 24 0,000 0,04903309 0,06376952 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05102394 0,06632286 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05102394 0,06628705 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05102394 0,06625127 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05102394 0,06621554 ! phototransduction GO:0007602 33 25 0,000 0,05102394 0,06617984 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05102394 0,06614419 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05102394 0,06610857 ! sperm motility GO:0030317 31 25 0,000 0,05102394 0,06607299 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05102394 0,06603744 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05102394 0,06600194 ! chromosome condensation GO:0030261 45 25 0,000 0,05102394 0,06596647 ! response to starvation GO:0042594 42 25 0,000 0,05102394 0,06593105 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05102394 0,06589566 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,05102394 0,06586031 ! neural crest cell development GO:0014032 54 25 0,000 0,05102394 0,06582499 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05102394 0,06578972 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05102394 0,06575448 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05102394 0,06571928 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05102394 0,06568411 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05102394 0,06564899 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05102394 0,0656139 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05102394 0,06557885 ! immunoglobulin production GO:0002377 55 25 0,000 0,05102394 0,06554384 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05102394 0,06550886 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05102394 0,06547393 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05102394 0,06543902 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05102394 0,06540416 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05102394 0,06536933 ! telomere organization GO:0032200 43 25 0,000 0,05102394 0,06533454 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05102394 0,06529979 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05102394 0,06526508 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0530107 0,06777032 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0530107 0,06773433 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0530107 0,06769838 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0530107 0,06766247 ! initiation of viral infection GO:0019059 57 26 0,000 0,0530107 0,06762659 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0530107 0,06759075 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0530107 0,06755495 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0530107 0,06751919 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0530107 0,06748346 ! molting cycle process GO:0022404 50 26 0,000 0,0530107 0,06744778 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,0530107 0,06741213 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0530107 0,06737652 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0530107 0,06734094 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0530107 0,06730541 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,0530107 0,06726991 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0530107 0,06723445 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0530107 0,06719902 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0530107 0,06716364 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0530107 0,06712829 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0530107 0,06709298 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0530107 0,0670577 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0530107 0,06702246 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0530107 0,06698726 ! blastocyst development GO:0001824 49 26 0,000 0,0530107 0,0669521 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0530107 0,06691697 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0530107 0,06688188 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05499336 0,06934698 ! neuron fate commitment GO:0048663 48 27 0,000 0,05499336 0,06931065 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05499336 0,06927436 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05499336 0,06923811 ! iron ion transport GO:0006826 59 27 0,000 0,05499336 0,0692019 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05499336 0,06916573 ! protein amino acid acylation GO:0043543 55 27 0,000 0,05499336 0,06912959 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05499336 0,06909349 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05499336 0,06905743 ! fat cell differentiation GO:0045444 50 27 0,000 0,05499336 0,06902141 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05499336 0,06898542 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05499336 0,06894947 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05499336 0,06891356 ! autophagy GO:0006914 41 27 0,000 0,05499336 0,06887769 ! male gonad development GO:0008584 44 27 0,000 0,05499336 0,06884185 ! response to toxin GO:0009636 47 27 0,000 0,05499336 0,06880605 ! primary neural tube formation GO:0014020 51 27 0,000 0,05499336 0,06877029 ! base-excision repair GO:0006284 41 27 0,000 0,05499336 0,06873456 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05499336 0,06869888 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05499336 0,06866323 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05499336 0,06862761 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05499336 0,06859203 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05499336 0,06855649 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05499336 0,06852099 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05499336 0,06848553 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05697194 0,07091283 ! circadian rhythm GO:0007623 50 28 0,000 0,05697194 0,07087616 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05697194 0,07083953 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05697194 0,07080294 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05697194 0,07076639 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05697194 0,07072987 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05697194 0,0706934 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05697194 0,07065696 ! synaptogenesis GO:0007416 42 28 0,000 0,05697194 0,07062055 ! lipid oxidation GO:0034440 43 28 0,000 0,05697194 0,07058419 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05697194 0,07054786 ! translational initiation GO:0006413 65 29 0,000 0,05894644 0,07295532 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05894644 0,07291781 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05894644 0,07288034 ! regulation of pH GO:0006885 43 29 0,000 0,05894644 0,07284291 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05894644 0,07280552 ! catechol metabolic process GO:0009712 54 29 0,000 0,05894644 0,07276816 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,05894644 0,07273084 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05894644 0,07269356 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05894644 0,07265632 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05894644 0,07261912 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05894644 0,07258196 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05894644 0,07254483 ! cell fate determination GO:0001709 60 29 0,000 0,05894644 0,07250774 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05894644 0,07247069 ! detection of light stimulus GO:0009583 38 29 0,000 0,05894644 0,07243368 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,05894644 0,0723967 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05894644 0,07235977 ! tissue homeostasis GO:0001894 48 29 0,000 0,05894644 0,07232287 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,05894644 0,07228601 ! phenol metabolic process GO:0018958 55 30 0,000 0,06091688 0,07466429 ! zinc ion transport GO:0006829 45 30 0,000 0,06091688 0,07462628 ! membrane docking GO:0022406 61 30 0,000 0,06091688 0,0745883 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06091688 0,07455036 ! cell junction assembly GO:0034329 78 30 0,000 0,06091688 0,07451246 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06091688 0,0744746 ! acute-phase response GO:0006953 49 30 0,000 0,06091688 0,07443677 ! myofibril assembly GO:0030239 47 30 0,000 0,06091688 0,07439899 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,06091688 0,07436124 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06091688 0,07432353 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06091688 0,07428586 ! phospholipid transport GO:0015914 51 30 0,000 0,06091688 0,07424823 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06091688 0,07421064 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06091688 0,07417308 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06091688 0,07413556 ! eye morphogenesis GO:0048592 60 30 0,000 0,06091688 0,07409808 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06091688 0,07406064 ! response to heat GO:0009408 50 30 0,000 0,06091688 0,07402323 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06288325 0,0763741 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06288325 0,07633557 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06288325 0,07629707 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06288325 0,07625862 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06288325 0,0762202 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06288325 0,07618182 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06288325 0,07614348 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06288325 0,07610518 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06288325 0,07606692 ! ovulation cycle process GO:0022602 49 31 0,000 0,06288325 0,07602869 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06288325 0,07599051 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06288325 0,07595236 ! peptide transport GO:0015833 55 31 0,000 0,06288325 0,07591425 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06288325 0,07587618 ! natural killer cell activation GO:0030101 45 31 0,000 0,06288325 0,07583814 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06288325 0,07580015 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06288325 0,07576219 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06288325 0,07572427 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06288325 0,07568639 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06484557 0,07800922 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06484557 0,07797023 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06484557 0,07793129 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06484557 0,07789238 ! cholesterol transport GO:0030301 56 32 0,000 0,06484557 0,07785351 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06484557 0,07781468 ! spliceosome assembly GO:0000245 67 32 0,000 0,06484557 0,07777589 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06484557 0,07773714 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06484557 0,07769843 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06484557 0,07765975 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06484557 0,07762111 ! muscle cell development GO:0055001 49 32 0,000 0,06484557 0,07758251 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06484557 0,07754396 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06484557 0,07750543 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06484557 0,07746695 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,06484557 0,07742851 ! ovulation cycle GO:0042698 51 32 0,000 0,06484557 0,0773901 ! hindbrain development GO:0030902 61 32 0,000 0,06484557 0,07735173 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06484557 0,0773134 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06484557 0,07727511 ! gene silencing GO:0016458 65 32 0,000 0,06484557 0,07723685 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06680384 0,07952996 ! post-embryonic development GO:0009791 69 33 0,000 0,06680384 0,07949063 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06680384 0,07945133 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06680384 0,07941208 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06680384 0,07937286 ! cell fate specification GO:0001708 52 33 0,000 0,06680384 0,07933369 ! sterol transport GO:0015918 57 33 0,000 0,06680384 0,07929455 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06680384 0,07925545 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06680384 0,07921639 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06680384 0,07917736 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06680384 0,07913838 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06875808 0,08141336 ! glial cell differentiation GO:0010001 63 34 0,000 0,06875808 0,08137332 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06875808 0,08133331 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06875808 0,08129334 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06875808 0,08125341 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,06875808 0,08121353 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06875808 0,08117368 ! mismatch repair GO:0006298 46 34 0,000 0,06875808 0,08113387 ! spermatid development GO:0007286 63 34 0,000 0,06875808 0,08109409 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,06875808 0,08105436 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06875808 0,08101467 ! placenta development GO:0001890 53 34 0,000 0,06875808 0,08097501 ! regulation of muscle development GO:0048634 70 35 0,000 0,0707083 0,083231 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0707083 0,0831903 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0707083 0,08314964 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0707083 0,08310902 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0707083 0,08306844 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0707083 0,0830279 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0707083 0,0829874 ! female gonad development GO:0008585 58 35 0,000 0,0707083 0,08294693 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0707083 0,08290651 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0707083 0,08286613 ! cytokine production GO:0001816 59 35 0,000 0,0707083 0,08282578 ! neural tube formation GO:0001841 67 35 0,000 0,0707083 0,08278548 ! vesicle localization GO:0051648 64 35 0,000 0,0707083 0,08274521 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07265449 0,08498138 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07265449 0,08494009 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07265449 0,08489884 ! cell junction organization GO:0034330 86 36 0,000 0,07265449 0,08485762 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07265449 0,08481645 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07265449 0,08477532 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07265449 0,08473422 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07265449 0,08469317 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07265449 0,08465216 ! aerobic respiration GO:0009060 55 36 0,000 0,07265449 0,08461118 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07265449 0,08457025 ! embryonic organ development GO:0048568 57 36 0,000 0,07265449 0,08452935 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07265449 0,0844885 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07459667 0,08670512 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07459667 0,08666325 ! meiosis I GO:0007127 65 37 0,000 0,07459667 0,08662142 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07459667 0,08657964 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07459667 0,08653789 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07459667 0,08649619 ! organic anion transport GO:0015711 68 37 0,000 0,07459667 0,08645452 ! tissue remodeling GO:0048771 76 37 0,000 0,07459667 0,0864129 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07459667 0,08637131 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07459667 0,08632977 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,07459667 0,08628827 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07459667 0,0862468 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,07459667 0,08620538 ! spermatid differentiation GO:0048515 66 37 0,000 0,07459667 0,08616399 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07653485 0,08836029 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07653485 0,08831791 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07653485 0,08827557 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07653485 0,08823328 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07653485 0,08819102 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07653485 0,0881488 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07653485 0,08810663 ! lipid homeostasis GO:0055088 67 38 0,000 0,07653485 0,08806449 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07653485 0,08802239 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07653485 0,08798034 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07653485 0,08793832 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,07653485 0,08789635 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07653485 0,08785441 ! glucan metabolic process GO:0044042 62 38 0,000 0,07653485 0,08781252 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,07846903 0,0899888 ! learning GO:0007612 77 39 0,000 0,07846903 0,08994592 ! ear morphogenesis GO:0042471 60 39 0,000 0,07846903 0,08990309 ! organic ether metabolic process GO:0018904 55 39 0,000 0,07846903 0,0898603 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07846903 0,08981755 ! segmentation GO:0035282 67 39 0,000 0,07846903 0,08977484 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07846903 0,08973217 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07846903 0,08968955 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,07846903 0,08964696 ! RNA modification GO:0009451 57 39 0,000 0,07846903 0,08960441 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07846903 0,0895619 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08039923 0,09172145 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08039923 0,09167798 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08039923 0,09163456 ! feeding behavior GO:0007631 59 40 0,000 0,08039923 0,09159117 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08039923 0,09154782 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08039923 0,09150452 ! cytokinesis GO:0000910 72 40 0,000 0,08039923 0,09146125 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08232545 0,09360824 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08232545 0,09356402 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08232545 0,09351984 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08232545 0,09347571 ! gliogenesis GO:0042063 88 41 0,000 0,08232545 0,09343162 ! T cell differentiation GO:0030217 81 41 0,000 0,08232545 0,09338757 ! female gamete generation GO:0007292 61 41 0,000 0,08232545 0,09334356 ! polyol metabolic process GO:0019751 66 41 0,000 0,08232545 0,09329959 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08232545 0,09325566 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08424769 0,09538821 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08424769 0,09534335 ! regulation of tube size GO:0035150 71 42 0,000 0,08424769 0,09529852 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08424769 0,09525374 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08424769 0,095209 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08424769 0,0951643 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08424769 0,09511964 ! neuron migration GO:0001764 79 42 0,000 0,08424769 0,09507502 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08424769 0,09503045 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08424769 0,09498592 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,08616598 0,09710321 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,08616598 0,09705775 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,08616598 0,09701233 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,08616598 0,09696695 ! glucose transport GO:0015758 65 43 0,000 0,08616598 0,09692162 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,08616598 0,09687633 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,08616598 0,09683108 ! neural tube development GO:0021915 77 43 0,000 0,08616598 0,09678588 ! striated muscle contraction GO:0006941 77 43 0,000 0,08616598 0,09674071 ! phagocytosis GO:0006909 90 43 0,000 0,08616598 0,09669559 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08808031 0,09879777 ! hexose transport GO:0008645 67 44 0,000 0,08808031 0,09875173 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,08808031 0,09870574 ! double-strand break repair GO:0006302 81 44 0,000 0,08808031 0,09865979 ! biopolymer methylation GO:0043414 84 44 0,000 0,08808031 0,09861388 ! B cell differentiation GO:0030183 107 44 0,000 0,08808031 0,09856801 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,08808031 0,09852219 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08808031 0,0984764 ! developmental growth GO:0048589 82 44 0,000 0,08808031 0,09843066 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,08999069 0,10051885 ! glycolysis GO:0006096 65 45 0,000 0,08999069 0,10047221 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,08999069 0,1004256 ! leukocyte migration GO:0050900 68 45 0,000 0,08999069 0,10037905 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08999069 0,10033253 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08999069 0,10028606 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08999069 0,10023963 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08999069 0,10019324 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08999069 0,1001469 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08999069 0,1001006 ! cell growth GO:0016049 84 45 0,000 0,08999069 0,10005434 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09189713 0,10212679 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09189713 0,10207964 ! pigmentation GO:0043473 100 46 0,000 0,09189713 0,10203254 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09379965 0,10409684 ! response to calcium ion GO:0051592 81 47 0,000 0,09379965 0,10404885 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09379965 0,1040009 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09379965 0,103953 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,09379965 0,10390514 ! JNK cascade GO:0007254 91 47 0,000 0,09379965 0,10385732 ! methylation GO:0032259 90 47 0,000 0,09379965 0,10380955 ! protein homooligomerization GO:0051260 76 47 0,000 0,09379965 0,10376182 ! mitochondrial transport GO:0006839 82 48 0,000 0,09569824 0,1058134 ! Notch signaling pathway GO:0007219 96 48 0,000 0,09569824 0,1057648 ! cellular component disassembly GO:0022411 86 48 0,000 0,09569824 0,10571624 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,09569824 0,10566772 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,09569824 0,10561925 ! activation of caspase activity GO:0006919 84 48 0,000 0,09569824 0,10557082 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,09569824 0,10552244 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,09569824 0,1054741 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,09759291 0,10751307 ! regulation of ion transport GO:0043269 77 49 0,000 0,09759291 0,10746387 ! peptide metabolic process GO:0006518 76 49 0,000 0,09759291 0,10741471 ! response to temperature stimulus GO:0009266 76 49 0,000 0,09759291 0,10736559 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,09759291 0,10731652 ! endocrine system development GO:0035270 104 49 0,000 0,09759291 0,1072675 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,09759291 0,10721852 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,09759291 0,10716958 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,09759291 0,10712069 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,09759291 0,10707184 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,09948368 0,10909651 ! neuromuscular process GO:0050905 99 50 0,000 0,09948368 0,10904681 ! inner ear development GO:0048839 79 50 0,000 0,09948368 0,10899715 ! histone modification GO:0016570 91 50 0,000 0,09948368 0,10894754 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,09948368 0,10889797 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,09948368 0,10884845 ! viral infectious cycle GO:0019058 99 51 0,000 0,10137055 0,11086252 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10137055 0,11081216 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10137055 0,11076183 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10137055 0,11071155 ! excretion GO:0007588 83 51 0,000 0,10137055 0,11066132 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10137055 0,11061114 ! chromatin remodeling GO:0006338 109 51 0,000 0,10137055 0,11056099 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10137055 0,1105109 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10137055 0,11046085 ! vesicle organization GO:0016050 107 51 0,000 0,10137055 0,11041084 ! regulation of cell shape GO:0008360 125 51 0,000 0,10137055 0,11036088 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,10325353 0,11236002 ! membrane fusion GO:0006944 110 52 0,000 0,10325353 0,11230922 ! covalent chromatin modification GO:0016569 101 52 0,000 0,10325353 0,11225847 ! amino acid activation GO:0043038 92 52 0,000 0,10325353 0,11220777 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10513263 0,11419824 ! RNA catabolic process GO:0006401 93 53 0,000 0,10513263 0,11414671 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10513263 0,11409522 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10513263 0,11404378 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10513263 0,11399239 ! cell maturation GO:0048469 100 53 0,000 0,10513263 0,11394104 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10513263 0,11388974 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,10513263 0,11383848 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,10700785 0,11581686 ! cell recognition GO:0008037 85 54 0,000 0,10700785 0,11576479 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,10700785 0,11571276 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,10700785 0,11566078 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,10700785 0,11560884 ! chloride transport GO:0006821 90 55 0,000 0,1088792 0,11757781 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,1088792 0,11752506 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,1088792 0,11747236 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,1088792 0,11741971 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,1088792 0,1173671 ! aging GO:0007568 103 55 0,000 0,1088792 0,11731454 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,1088792 0,11726203 ! RNA elongation GO:0006354 79 55 0,000 0,1088792 0,11720956 ! nuclear export GO:0051168 97 55 0,000 0,1088792 0,11715714 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,1088792 0,11710477 ! regulation of actin filament length GO:0030832 105 56 0,000 0,1107467 0,11906012 ! sensory perception of smell GO:0007608 80 56 0,000 0,1107467 0,11900695 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,1107467 0,11895382 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,1107467 0,11890074 ! proton transport GO:0015992 94 56 0,000 0,1107467 0,11884771 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,1107467 0,11879472 ! hydrogen transport GO:0006818 97 58 0,000 0,11447014 0,12273403 ! regulation of endocytosis GO:0030100 91 58 0,000 0,11447014 0,12267936 ! adult behavior GO:0030534 99 58 0,000 0,11447014 0,12262474 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1163261 0,12455746 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1163261 0,12450205 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,1163261 0,12444669 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1163261 0,12439138 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,1163261 0,12433612 ! DNA catabolic process GO:0006308 86 59 0,000 0,1163261 0,12428091 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1163261 0,12422574 ! establishment of organelle localization GO:0051656 109 59 0,000 0,1163261 0,12417063 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,11817824 0,12609172 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,11817824 0,12603583 ! regulation of heart contraction GO:0008016 110 60 0,000 0,11817824 0,12597999 ! camera-type eye development GO:0043010 116 60 0,000 0,11817824 0,1259242 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,11817824 0,12586845 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12002655 0,12778048 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,12002655 0,12772396 ! tRNA processing GO:0008033 89 61 0,000 0,12002655 0,1276675 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12002655 0,12761108 ! ear development GO:0043583 103 62 0,000 0,12187105 0,12951491 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12187105 0,12945773 ! gonad development GO:0008406 98 62 0,000 0,12187105 0,1294006 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,12187105 0,12934352 ! regulation of mitosis GO:0007088 105 63 0,000 0,12371175 0,13123918 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12371175 0,13118134 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,12371175 0,13112355 ! detection of external stimulus GO:0009581 91 63 0,000 0,12371175 0,13106582 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12371175 0,13100813 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,12371175 0,13095049 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,12554865 0,13283643 ! cell redox homeostasis GO:0045454 102 64 0,000 0,12554865 0,13277804 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,12554865 0,1327197 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,12554865 0,13266142 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,12738176 0,13453929 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,12738176 0,13448026 ! germ cell development GO:0007281 118 65 0,000 0,12738176 0,13442127 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,12921108 0,13629192 ! extracellular matrix organization GO:0030198 133 66 0,000 0,12921108 0,13623219 ! secondary metabolic process GO:0019748 116 66 0,000 0,12921108 0,13617252 ! developmental maturation GO:0021700 116 66 0,000 0,12921108 0,1361129 ! cell projection assembly GO:0030031 120 66 0,000 0,12921108 0,13605333 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13103664 0,1379152 ! chromosome segregation GO:0007059 113 67 0,000 0,13103664 0,1378549 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13103664 0,13779465 ! hexose catabolic process GO:0019320 104 67 0,000 0,13103664 0,13773445 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,13103664 0,1376743 ! adaptive immune response GO:0002250 119 67 0,000 0,13103664 0,13761421 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13103664 0,13755417 ! amino acid transport GO:0006865 125 68 0,000 0,13285842 0,13940574 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13285842 0,13934497 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,13285842 0,13928426 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,13285842 0,13922359 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,13285842 0,13916298 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,13285842 0,13910242 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,13467645 0,14094456 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,13467645 0,14088328 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,13467645 0,14082205 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,13467645 0,14076088 ! antigen processing and presentation GO:0019882 104 69 0,000 0,13467645 0,14069976 ! amine catabolic process GO:0009310 117 71 0,000 0,13830126 0,14442397 ! reproductive structure development GO:0048608 113 71 0,000 0,13830126 0,14436132 ! humoral immune response GO:0006959 109 71 0,000 0,13830126 0,14429871 ! B cell activation GO:0042113 160 71 0,000 0,13830126 0,14423617 ! regulation of immune effector process GO:0002697 137 71 0,000 0,13830126 0,14417367 ! acute inflammatory response GO:0002526 113 72 0,000 0,14010806 0,14599393 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14010806 0,14593073 ! carbohydrate transport GO:0008643 110 72 0,000 0,14010806 0,14586758 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14010806 0,14580449 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14010806 0,14574146 ! learning or memory GO:0007611 147 73 0,000 0,14191113 0,14755323 ! fertilization GO:0009566 90 73 0,000 0,14191113 0,14748949 ! transition metal ion transport GO:0000041 126 74 0,000 0,14371047 0,14929508 ! neurotransmitter transport GO:0006836 123 74 0,000 0,14371047 0,14923064 ! meiosis GO:0007126 121 74 0,000 0,14371047 0,14916626 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,14371047 0,14910194 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,14371047 0,14903767 ! eye development GO:0001654 143 74 0,000 0,14371047 0,14897346 ! organelle localization GO:0051640 136 74 0,000 0,14371047 0,1489093 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,14550611 0,15070499 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,14550611 0,15064015 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,14550611 0,15057535 ! meiotic cell cycle GO:0051321 122 75 0,000 0,14550611 0,15051062 ! rhythmic process GO:0048511 128 75 0,000 0,14550611 0,15044594 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,14550611 0,15038131 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,14729804 0,15216792 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,14729804 0,15210261 ! defense response to bacterium GO:0042742 89 76 0,000 0,14729804 0,15203736 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,14729804 0,15197216 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,14908627 0,1537512 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,14908627 0,15368533 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,14908627 0,15361951 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,14908627 0,15355375 ! blood coagulation GO:0007596 146 78 0,000 0,15087081 0,15532527 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15087081 0,15525884 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,15087081 0,15519246 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,15265166 0,15695722 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,15265166 0,15689018 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,15265166 0,15682319 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,15265166 0,15675625 ! response to metal ion GO:0010038 140 80 0,000 0,15442884 0,15851357 ! muscle cell differentiation GO:0042692 159 80 0,000 0,15442884 0,15844597 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,15442884 0,15837843 ! protein import into nucleus GO:0006606 158 80 0,000 0,15442884 0,15831095 ! inorganic anion transport GO:0015698 138 80 0,000 0,15442884 0,15824353 ! T cell activation GO:0042110 168 81 0,000 0,15620236 0,15999271 ! digestion GO:0007586 112 81 0,000 0,15620236 0,15992462 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,15620236 0,1598566 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,15620236 0,15978863 ! nuclear import GO:0051170 161 81 0,000 0,15620236 0,15972073 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,15620236 0,15965287 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,15797221 0,16139326 ! response to drug GO:0042493 143 82 0,000 0,15797221 0,16132476 ! response to nutrient GO:0007584 125 82 0,000 0,15797221 0,16125631 ! hemostasis GO:0007599 158 84 0,000 0,16150096 0,16478851 ! regulation of ligase activity GO:0051340 142 84 0,000 0,16150096 0,16471865 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,16150096 0,16464886 ! response to unfolded protein GO:0006986 131 85 0,000 0,16325987 0,16637156 ! nucleosome assembly GO:0006334 122 85 0,000 0,16325987 0,16630112 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,16325987 0,16623074 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,16325987 0,16616043 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,16501515 0,16787588 ! response to inorganic substance GO:0010035 153 86 0,000 0,16501515 0,16780493 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,16501515 0,16773403 ! chromatin assembly GO:0031497 124 86 0,000 0,16501515 0,1676632 ! alcohol catabolic process GO:0046164 130 86 0,000 0,16501515 0,16759242 ! amine transport GO:0015837 155 86 0,000 0,16501515 0,16752171 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,16676681 0,16922857 ! protein localization in nucleus GO:0034504 176 87 0,000 0,16676681 0,16915723 ! cellular respiration GO:0045333 135 88 0,000 0,16851485 0,17085829 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,16851485 0,17078632 ! regulation of neurological system process GO:0031644 148 88 0,000 0,16851485 0,17071441 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,16851485 0,17064256 ! cellular defense response GO:0006968 114 89 0,000 0,17025928 0,17233649 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,17025928 0,17226402 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,17200011 0,1739522 ! sex differentiation GO:0007548 145 90 0,000 0,17200011 0,17387911 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,17200011 0,17380608 ! sterol metabolic process GO:0016125 152 91 0,000 0,17373735 0,17548785 ! response to protein stimulus GO:0051789 149 91 0,000 0,17373735 0,17541421 ! regulation of defense response GO:0031347 149 92 0,000 0,175471 0,17709028 ! nucleosome organization GO:0034728 138 92 0,000 0,175471 0,17701603 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,175471 0,17694184 ! vitamin metabolic process GO:0006766 139 92 0,000 0,175471 0,17686771 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,17720107 0,17853676 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,17720107 0,17846202 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,17892757 0,18012541 ! female pregnancy GO:0007565 164 94 0,000 0,17892757 0,18005007 ! transcription initiation GO:0006352 153 94 0,000 0,17892757 0,1799748 ! forebrain development GO:0030900 188 95 0,000 0,1806505 0,18163188 ! leukocyte differentiation GO:0002521 202 96 0,000 0,18236987 0,183284 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,18236987 0,18320748 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,18236987 0,18313101 ! positive regulation of immune response GO:0050778 156 96 0,000 0,18236987 0,18305461 ! detection of stimulus GO:0051606 151 96 0,000 0,18236987 0,18297828 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,18408569 0,18462283 ! protein ubiquitination GO:0016567 217 97 0,000 0,18408569 0,18454591 ! hormone metabolic process GO:0042445 157 97 0,000 0,18408569 0,18446904 ! response to virus GO:0009615 160 98 0,000 0,18579797 0,18610738 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,18579797 0,18602993 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,18579797 0,18595254 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,18750671 0,18758468 ! cell cycle arrest GO:0007050 213 100 0,000 0,18921193 0,18921193