pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6334-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 5,755E-11 1,406E-07 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 2,4E-09 2,932E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 5,642E-09 4,594E-06 ! cell killing GO:0001906 32 15 3,000 1,549E-08 9,461E-06 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 1,43E-07 6,986E-05 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 3,561E-07 1,45E-04 ! spindle organization GO:0007051 50 32 3,000 3,984E-07 1,39E-04 ! receptor clustering GO:0043113 20 9 2,000 5,334E-07 1,629E-04 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 5,967E-07 1,62E-04 ! positive regulation of MAP kinase activity GO:0043406 174 93 4,000 9,344E-07 2,283E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 2,296E-06 5,099E-04 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 32 14 2,000 2,296E-06 4,674E-04 ! positive regulation of biomineral formation GO:0070169 33 15 2,000 2,866E-06 5,385E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 4,224E-06 7,37E-04 ! signal complex assembly GO:0007172 47 17 2,000 4,271E-06 6,957E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 5,119E-06 7,816E-04 ! neuromuscular junction development GO:0007528 43 19 2,000 6,07E-06 8,723E-04 ! positive regulation of ossification GO:0045778 50 20 2,000 7,132E-06 9,68E-04 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 7,158E-06 9,203E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 8,309E-06 1,015E-03 ! positive regulation of osteoblast differentiation GO:0045669 52 21 2,000 8,309E-06 9,666E-04 ! positive regulation of bone remodeling GO:0046852 54 22 2,000 9,608E-06 1,067E-03 GO:0034105|positive regulation of tissue remodeling, ! ureteric bud development GO:0001657 50 22 2,000 9,608E-06 1,021E-03 ! regulation of bone mineralization GO:0030500 54 23 2,000 1,103E-05 1,123E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,259E-05 1,231E-03 ! leukocyte mediated immunity GO:0002443 136 75 3,000 1,267E-05 1,19E-03 ! receptor metabolic process GO:0043112 53 25 2,000 1,429E-05 1,293E-03 ! regulation of biomineral formation GO:0070167 56 25 2,000 1,429E-05 1,247E-03 ! regulation of osteoblast differentiation GO:0045667 68 26 2,000 1,613E-05 1,359E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,813E-05 1,476E-03 ! dendrite development GO:0016358 67 28 2,000 2,027E-05 1,598E-03 ! metanephros development GO:0001656 81 32 2,000 3,053E-05 2,331E-03 ! BMP signaling pathway GO:0030509 71 32 2,000 3,053E-05 2,26E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 3,487E-05 2,506E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,487E-05 2,434E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,487E-05 2,367E-03 ! nucleobase transport GO:0015851 6 5 1,000 3,487E-05 2,303E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,487E-05 2,242E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 5,151E-05 3,227E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 5,225E-05 3,191E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 5,225E-05 3,113E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 7,306E-05 4,25E-03 ! male sex determination GO:0030238 15 7 1,000 7,306E-05 4,151E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 7,306E-05 4,056E-03 ! protein amino acid prenylation GO:0018346 19 7 1,000 7,306E-05 3,966E-03 ! hormone-mediated signaling GO:0009755 84 43 2,000 7,485E-05 3,975E-03 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 8,583E-05 4,461E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 8,583E-05 4,368E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 9,169E-05 4,572E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 9,729E-05 4,754E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 9,729E-05 4,66E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 9,729E-05 4,571E-03 ! gas homeostasis GO:0033483 14 8 1,000 9,729E-05 4,485E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 9,729E-05 4,402E-03 ! protein prenylation GO:0018342 21 8 1,000 9,729E-05 4,322E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 9,781E-05 4,267E-03 ! regulation of ossification GO:0030278 123 50 2,000 1,178E-04 5,047E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,249E-04 5,262E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,249E-04 5,173E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 1,249E-04 5,087E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,249E-04 5,004E-03 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 1,324E-04 5,218E-03 ! positive regulation of growth GO:0045927 96 53 2,000 1,402E-04 5,436E-03 ! synapse organization GO:0050808 102 53 2,000 1,402E-04 5,351E-03 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,482E-04 5,571E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 1,56E-04 5,774E-03 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,56E-04 5,688E-03 ! lung alveolus development GO:0048286 26 10 1,000 1,56E-04 5,604E-03 ! motor axon guidance GO:0008045 22 10 1,000 1,56E-04 5,523E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 1,56E-04 5,444E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,56E-04 5,367E-03 GO:0045685|regulation of glial cell differentiation, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,56E-04 5,293E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,56E-04 5,22E-03 GO:0043470|regulation of carbohydrate catabolic process, ! skeletal muscle fiber development GO:0048741 130 56 2,000 1,652E-04 5,454E-03 ! regulation of bone remodeling GO:0046850 143 57 2,000 1,741E-04 5,672E-03 ! muscle fiber development GO:0048747 131 57 2,000 1,741E-04 5,598E-03 ! heart morphogenesis GO:0003007 105 57 2,000 1,741E-04 5,525E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 1,834E-04 5,744E-03 ! regulation of tissue remodeling GO:0034103 146 58 2,000 1,834E-04 5,671E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,904E-04 5,815E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,904E-04 5,743E-03 ! cardiac cell differentiation GO:0035051 36 11 1,000 1,904E-04 5,673E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 1,904E-04 5,605E-03 ! kidney development GO:0001822 133 60 2,000 2,028E-04 5,899E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,282E-04 6,559E-03 ! virus-host interaction GO:0019048 30 12 1,000 2,282E-04 6,483E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,282E-04 6,408E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,282E-04 6,336E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 2,282E-04 6,264E-03 GO:0042130|negative regulation of T cell proliferation, ! localization within membrane GO:0051668 26 12 1,000 2,282E-04 6,195E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 2,456E-04 6,595E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 2,572E-04 6,829E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 2,694E-04 7,076E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,694E-04 7,001E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,694E-04 6,927E-03 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,694E-04 6,855E-03 ! urogenital system development GO:0001655 149 69 2,000 3,068E-04 7,728E-03 ! negative regulation of caspase activity GO:0043154 23 14 1,000 3,139E-04 7,825E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 3,139E-04 7,746E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3,617E-04 8,837E-03 ! heme biosynthetic process GO:0006783 33 15 1,000 3,617E-04 8,75E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 3,617E-04 8,664E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,129E-04 9,794E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 4,129E-04 9,7E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,129E-04 9,607E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 4,129E-04 9,517E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of catabolic process GO:0009894 173 77 2,000 4,238E-04 9,676E-03 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 4,674E-04 0,01057297 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 4,674E-04 0,01047597 GO:0031114|regulation of microtubule depolymerization, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 4,741E-04 0,01052895 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 5,252E-04 0,01155903 ! porphyrin biosynthetic process GO:0006779 37 18 1,000 5,252E-04 0,01145583 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 5,252E-04 0,01135445 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 5,252E-04 0,01125485 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 5,252E-04 0,01115698 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 5,252E-04 0,0110608 ! heme metabolic process GO:0042168 40 19 1,000 5,863E-04 0,0122415 ! proximal/distal pattern formation GO:0009954 33 19 1,000 5,863E-04 0,01213776 ! regulation of DNA binding GO:0051101 167 89 2,000 6,474E-04 0,01329101 ! tube morphogenesis GO:0035239 194 89 2,000 6,474E-04 0,01318026 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 6,506E-04 0,01313602 ! skin development GO:0043588 42 20 1,000 6,506E-04 0,01302835 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 6,506E-04 0,01292243 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 6,506E-04 0,01281822 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 6,506E-04 0,01271567 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 6,506E-04 0,01261475 ! negative regulation of T cell activation GO:0050868 41 20 1,000 6,506E-04 0,01251543 ! lipid phosphorylation GO:0046834 43 21 1,000 7,182E-04 0,01370808 ! regulation of vasoconstriction GO:0019229 40 21 1,000 7,182E-04 0,01360181 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 7,891E-04 0,01482884 ! protein stabilization GO:0050821 41 22 1,000 7,891E-04 0,01471565 ! positive regulation of DNA replication GO:0045740 44 23 1,000 8,632E-04 0,01597559 ! skeletal muscle tissue development GO:0007519 223 100 2,000 9,083E-04 0,01668427 GO:0060538|skeletal muscle organ development, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 9,405E-04 0,01714692 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 9,405E-04 0,01701991 ! sex determination GO:0007530 48 24 1,000 9,405E-04 0,01689476 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 9,405E-04 0,01677144 ! porphyrin metabolic process GO:0006778 50 24 1,000 9,405E-04 0,01664991 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 1,000 9,405E-04 0,01653013 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 9,405E-04 0,01641205 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,021E-03 0,01769114 ! interaction with host GO:0051701 66 25 1,000 1,021E-03 0,01756655 ! protein tetramerization GO:0051262 57 25 1,000 1,021E-03 0,01744371 ! myelination GO:0042552 50 26 1,000 1,105E-03 0,01874331 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,105E-03 0,01861405 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,105E-03 0,01848655 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 1,105E-03 0,01836079 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 1,192E-03 0,01967174 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 1,192E-03 0,01953971 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,282E-03 0,02087708 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 1,282E-03 0,02073882 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,282E-03 0,02060238 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 1,282E-03 0,02046772 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 1,375E-03 0,02181456 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,375E-03 0,02167382 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 1,472E-03 0,02304506 GO:0043433|negative regulation of transcription factor activity, ! iron ion homeostasis GO:0055072 60 31 1,000 1,571E-03 0,02444774 ! erythrocyte differentiation GO:0030218 62 31 1,000 1,571E-03 0,02429301 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 1,571E-03 0,02414022 ! ensheathment of neurons GO:0007272 64 31 1,000 1,571E-03 0,02398934 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 1,571E-03 0,02384034 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,674E-03 0,02524203 ! mesoderm formation GO:0001707 73 32 1,000 1,674E-03 0,02508717 ! peripheral nervous system development GO:0007422 68 32 1,000 1,674E-03 0,0249342 ! positive regulation of catabolic process GO:0009896 72 32 1,000 1,674E-03 0,02478308 ! pigment biosynthetic process GO:0046148 73 33 1,000 1,78E-03 0,02619122 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 1,78E-03 0,02603439 ! negative regulation of protein transport GO:0051224 74 33 1,000 1,78E-03 0,02587942 ! formation of primary germ layer GO:0001704 76 34 1,000 1,889E-03 0,02730099 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 1,889E-03 0,0271404 ! mesoderm morphogenesis GO:0048332 80 35 1,000 2,001E-03 0,02858219 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,001E-03 0,02841602 ! negative regulation of DNA binding GO:0043392 67 36 1,000 2,116E-03 0,02987732 ! positive regulation of cell development GO:0010720 85 36 1,000 2,116E-03 0,02970561 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 2,116E-03 0,02953586 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 2,234E-03 0,03100854 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! odontogenesis GO:0042476 74 37 1,000 2,234E-03 0,03083335 ! maintenance of protein location in cell GO:0032507 89 37 1,000 2,234E-03 0,03066013 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,234E-03 0,03048884 ! negative regulation of cell activation GO:0050866 69 37 1,000 2,234E-03 0,03031946 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 2,355E-03 0,03178843 ! regulation of protein stability GO:0031647 77 38 1,000 2,355E-03 0,03161377 ! pigment metabolic process GO:0042440 87 38 1,000 2,355E-03 0,03144102 ! negative regulation of binding GO:0051100 71 39 1,000 2,479E-03 0,03292043 ! carbohydrate homeostasis GO:0033500 59 39 1,000 2,479E-03 0,03274248 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 2,479E-03 0,03256644 ! mammary gland development GO:0030879 93 40 1,000 2,607E-03 0,03405578 ! regulation of action potential in neuron GO:0019228 80 40 1,000 2,607E-03 0,03387463 ! mesenchymal cell development GO:0014031 94 41 1,000 2,737E-03 0,0353804 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 95 41 1,000 2,737E-03 0,03519419 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 2,871E-03 0,03671583 ! regulation of T cell differentiation GO:0045580 78 42 1,000 2,871E-03 0,03652461 ! regulation of T cell proliferation GO:0042129 80 43 1,000 3,007E-03 0,0380616 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 3,146E-03 0,03962042 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 3,146E-03 0,03941724 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 3,146E-03 0,03921613 ! heterocycle biosynthetic process GO:0018130 76 44 1,000 3,146E-03 0,03901706 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 3,289E-03 0,04057633 ! keratinocyte differentiation GO:0030216 81 45 1,000 3,289E-03 0,04037243 ! maintenance of location in cell GO:0051651 101 45 1,000 3,289E-03 0,04017057 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 3,434E-03 0,04173691 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 3,434E-03 0,04153029 ! positive regulation of protein transport GO:0051222 80 46 1,000 3,434E-03 0,04132571 ! regulation of JNK cascade GO:0046328 104 47 1,000 3,582E-03 0,04289877 ! positive regulation of cell cycle GO:0045787 96 48 1,000 3,733E-03 0,04449158 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 3,733E-03 0,0442756 ! endosome transport GO:0016197 127 48 1,000 3,733E-03 0,04406171 ! positive regulation of DNA binding GO:0043388 83 48 1,000 3,733E-03 0,04384988 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 3,888E-03 0,04544196 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 3,888E-03 0,04522557 ! regulation of action potential GO:0001508 102 50 1,000 4,045E-03 0,04682989 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 4,045E-03 0,04660899 ! epidermal cell differentiation GO:0009913 87 50 1,000 4,045E-03 0,04639017 ! negative regulation of immune system process GO:0002683 101 51 1,000 4,205E-03 0,04799981 ! positive regulation of binding GO:0051099 88 52 1,000 4,368E-03 0,04962743 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 4,368E-03 0,04939767 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 4,533E-03 0,05103638 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 1,000 4,533E-03 0,05080227 ! regulation of angiogenesis GO:0045765 125 54 1,000 4,702E-03 0,05245171 ! protein amino acid lipidation GO:0006497 109 54 1,000 4,702E-03 0,0522133 ! activation of phospholipase C activity GO:0007202 110 54 1,000 4,702E-03 0,05197704 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 4,874E-03 0,05363045 ! response to UV GO:0009411 120 55 1,000 4,874E-03 0,05338996 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 5,048E-03 0,05505346 ! regulation of protein catabolic process GO:0042176 126 56 1,000 5,048E-03 0,05480878 ! regulation of DNA replication GO:0006275 105 56 1,000 5,048E-03 0,05456626 ! regulation of phospholipase activity GO:0010517 113 57 1,000 5,225E-03 0,05623322 ! regulation of intracellular transport GO:0032386 108 57 1,000 5,225E-03 0,05598658 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 5,405E-03 0,05766301 ! gastrulation GO:0007369 122 58 1,000 5,405E-03 0,0574123 ! positive regulation of lipase activity GO:0060193 115 58 1,000 5,405E-03 0,05716376 ! maintenance of location GO:0051235 124 58 1,000 5,405E-03 0,05691737 ! lipid modification GO:0030258 112 60 1,000 5,774E-03 0,06053766 ! viral reproductive process GO:0022415 132 62 1,000 6,154E-03 0,064244 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 6,154E-03 0,06397062 ! mesoderm development GO:0007498 128 63 1,000 6,348E-03 0,0657085 ! negative regulation of cell growth GO:0030308 142 67 1,000 7,151E-03 0,0737174 ! activation of MAPK activity GO:0000187 124 67 1,000 7,151E-03 0,07340767 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 7,151E-03 0,07310052 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 1,000 7,151E-03 0,07279594 ! regulation of cellular response to stress GO:0080135 142 68 1,000 7,359E-03 0,07460039 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 7,359E-03 0,07429212 ! viral reproduction GO:0016032 142 68 1,000 7,359E-03 0,07398639 ! regulation of lipase activity GO:0060191 137 68 1,000 7,359E-03 0,07368317 ! negative regulation of cell size GO:0045792 144 69 1,000 7,57E-03 0,07548161 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 7,57E-03 0,07517478 ! lung development GO:0030324 165 69 1,000 7,57E-03 0,07487042 ! homeostasis of number of cells GO:0048872 131 69 1,000 7,57E-03 0,07456853 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 7,57E-03 0,07426906 ! negative regulation of kinase activity GO:0033673 145 70 1,000 7,783E-03 0,07605561 ! cAMP-mediated signaling GO:0019933 124 71 1,000 7,999E-03 0,07785416 ! appendage morphogenesis GO:0035107 150 72 1,000 8,218E-03 0,07966444 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 8,218E-03 0,07934956 ! actin filament organization GO:0007015 167 72 1,000 8,218E-03 0,07903716 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 8,218E-03 0,07872721 ! appendage development GO:0048736 151 73 1,000 8,439E-03 0,0805313 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 8,663E-03 0,08234666 ! negative regulation of transferase activity GO:0051348 155 74 1,000 8,663E-03 0,08202748 ! respiratory system development GO:0060541 175 74 1,000 8,663E-03 0,08171077 ! regulation of transcription factor activity GO:0051090 137 75 1,000 8,889E-03 0,08352556 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 8,889E-03 0,08320554 ! axon guidance GO:0007411 162 75 1,000 8,889E-03 0,08288796 ! regulation of blood pressure GO:0008217 134 76 1,000 9,119E-03 0,08470211 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 9,35E-03 0,08652685 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 9,35E-03 0,08620034 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 9,39E-03 0,08623973 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 9,39E-03 0,08591674 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 9,39E-03 0,08559615 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,39E-03 0,08527795 ! positive regulation of helicase activity GO:0051096 12 5 0,000 9,39E-03 0,08496211 ! neuron fate determination GO:0048664 7 5 0,000 9,39E-03 0,08464859 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,39E-03 0,08433739 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 9,39E-03 0,08402846 ! polyol transport GO:0015791 12 5 0,000 9,39E-03 0,08372178 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,39E-03 0,08341734 ! response to superoxide GO:0000303 10 5 0,000 9,39E-03 0,08311511 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,39E-03 0,08281505 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 9,39E-03 0,08251715 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 9,39E-03 0,08222139 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,39E-03 0,08192775 ! female meiosis GO:0007143 10 5 0,000 9,39E-03 0,08163619 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 9,39E-03 0,0813467 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,39E-03 0,08105925 ! hypothalamus development GO:0021854 9 5 0,000 9,39E-03 0,08077383 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 9,39E-03 0,08049042 ! cobalt ion transport GO:0006824 11 5 0,000 9,39E-03 0,08020898 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 9,39E-03 0,07992951 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 9,39E-03 0,07965198 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,39E-03 0,07937636 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,39E-03 0,07910265 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 9,39E-03 0,07883082 ! embryonic camera-type eye development GO:0031076 12 5 0,000 9,39E-03 0,07856085 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,39E-03 0,07829273 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,39E-03 0,07802643 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 9,39E-03 0,07776193 ! transposition GO:0032196 9 5 0,000 9,39E-03 0,07749922 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 9,39E-03 0,07723828 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 9,39E-03 0,07697909 ! negative chemotaxis GO:0050919 16 5 0,000 9,39E-03 0,07672164 ! positive regulation of histone modification GO:0031058 6 5 0,000 9,39E-03 0,0764659 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,39E-03 0,07621186 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 9,39E-03 0,0759595 ! behavioral response to pain GO:0048266 10 5 0,000 9,39E-03 0,07570881 ! clathrin coat assembly GO:0048268 15 5 0,000 9,39E-03 0,07545977 ! Notch receptor processing GO:0007220 11 5 0,000 9,39E-03 0,07521236 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,39E-03 0,07496657 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 9,39E-03 0,07472237 ! micturition GO:0060073 9 5 0,000 9,39E-03 0,07447977 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,39E-03 0,07423873 ! copulation GO:0007620 9 5 0,000 9,39E-03 0,07399926 ! glial cell fate commitment GO:0021781 14 5 0,000 9,39E-03 0,07376132 ! protein maturation by protein folding GO:0022417 14 5 0,000 9,39E-03 0,0735249 ! bioluminescence GO:0008218 9 5 0,000 9,39E-03 0,07329 ! spermidine metabolic process GO:0008216 7 5 0,000 9,39E-03 0,07305659 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,39E-03 0,07282466 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,39E-03 0,07259421 ! apoptotic cell clearance GO:0043277 23 5 0,000 9,39E-03 0,0723652 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,39E-03 0,07213764 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 9,39E-03 0,0719115 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,39E-03 0,07168678 ! grooming behavior GO:0007625 6 5 0,000 9,39E-03 0,07146346 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 9,39E-03 0,07124152 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,39E-03 0,07102096 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 9,39E-03 0,07080176 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,39E-03 0,0705839 ! response to protozoan GO:0001562 13 5 0,000 9,39E-03 0,07036739 ! lymph vessel development GO:0001945 10 5 0,000 9,39E-03 0,0701522 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 9,39E-03 0,06993832 ! endochondral ossification GO:0001958 17 5 0,000 9,39E-03 0,06972574 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,39E-03 0,06951445 ! single strand break repair GO:0000012 8 5 0,000 9,39E-03 0,06930444 ! parathyroid gland development GO:0060017 14 5 0,000 9,39E-03 0,06909569 ! anagen GO:0042640 7 5 0,000 9,39E-03 0,0688882 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,39E-03 0,06868194 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,39E-03 0,06847692 ! cytokine secretion GO:0050663 15 5 0,000 9,39E-03 0,06827312 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 9,39E-03 0,06807053 ! ceramide catabolic process GO:0046514 7 5 0,000 9,39E-03 0,06786914 ! skeletal myofibril assembly GO:0014866 12 5 0,000 9,39E-03 0,06766894 ! smooth muscle tissue development GO:0048745 32 5 0,000 9,39E-03 0,06746991 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,39E-03 0,06727205 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,39E-03 0,06707535 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,39E-03 0,06687979 ! cardiac muscle fiber development GO:0048739 12 5 0,000 9,39E-03 0,06668538 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,39E-03 0,06649208 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 9,39E-03 0,06629991 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,39E-03 0,06610884 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 9,39E-03 0,06591888 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,39E-03 0,06573 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 9,39E-03 0,0655422 ! glycine biosynthetic process GO:0006545 7 5 0,000 9,39E-03 0,06535547 ! microvillus organization GO:0032528 8 5 0,000 9,39E-03 0,0651698 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 9,39E-03 0,06498518 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 9,39E-03 0,06480161 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 9,39E-03 0,06461907 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 9,39E-03 0,06443755 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 9,39E-03 0,06425706 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 9,39E-03 0,06407757 ! polyol catabolic process GO:0046174 9 5 0,000 9,39E-03 0,06389908 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 9,39E-03 0,06372158 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 9,39E-03 0,06354507 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 9,39E-03 0,06336953 ! muscle cell migration GO:0014812 8 5 0,000 9,39E-03 0,06319496 ! mitochondrial fission GO:0000266 8 5 0,000 9,39E-03 0,06302134 ! sister chromatid cohesion GO:0007062 15 5 0,000 9,39E-03 0,06284868 ! response to tumor necrosis factor GO:0034612 10 5 0,000 9,39E-03 0,06267696 ! mRNA transcription GO:0009299 10 5 0,000 9,39E-03 0,06250618 ! nerve growth factor processing GO:0032455 9 5 0,000 9,39E-03 0,06233633 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 9,39E-03 0,0621674 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 9,39E-03 0,06199938 ! anaerobic glycolysis GO:0019642 6 5 0,000 9,39E-03 0,06183226 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,39E-03 0,06166605 ! monocyte activation GO:0042117 10 5 0,000 9,39E-03 0,06150072 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,39E-03 0,06133628 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,39E-03 0,06117272 ! response to food GO:0032094 6 5 0,000 9,39E-03 0,06101002 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,39E-03 0,06084819 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,39E-03 0,06068722 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 9,39E-03 0,0605271 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,39E-03 0,06036781 ! forebrain neuron development GO:0021884 13 5 0,000 9,39E-03 0,06020937 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,39E-03 0,06005175 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 9,39E-03 0,05989496 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 9,39E-03 0,05973898 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,39E-03 0,05958382 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,39E-03 0,05942945 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 9,39E-03 0,05927589 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,39E-03 0,05912312 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 9,39E-03 0,05897113 ! lipid glycosylation GO:0030259 7 5 0,000 9,39E-03 0,05881992 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,39E-03 0,05866949 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 9,39E-03 0,05851982 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 9,39E-03 0,05837091 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 9,39E-03 0,05822276 ! basic amino acid transport GO:0015802 12 5 0,000 9,39E-03 0,05807536 ! cellular glucose homeostasis GO:0001678 6 5 0,000 9,39E-03 0,05792871 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 9,39E-03 0,05778279 ! actin nucleation GO:0045010 11 5 0,000 9,39E-03 0,05763761 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,39E-03 0,05749316 ! depurination GO:0045007 5 5 0,000 9,39E-03 0,05734942 ! depyrimidination GO:0045008 10 5 0,000 9,39E-03 0,05720641 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,39E-03 0,0570641 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,39E-03 0,0569225 ! G2/M transition checkpoint GO:0031576 8 5 0,000 9,39E-03 0,05678161 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,39E-03 0,05664141 ! zinc ion homeostasis GO:0055069 9 5 0,000 9,39E-03 0,05650189 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 9,39E-03 0,05636307 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 9,39E-03 0,05622492 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,39E-03 0,05608745 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,39E-03 0,05595066 ! activated T cell proliferation GO:0050798 16 5 0,000 9,39E-03 0,05581452 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,39E-03 0,05567905 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 9,39E-03 0,05554424 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,39E-03 0,05541007 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,39E-03 0,05527655 ! gamma-delta T cell activation GO:0046629 6 5 0,000 9,39E-03 0,05514368 ! response to arsenic GO:0046685 11 5 0,000 9,39E-03 0,05501144 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 9,39E-03 0,05487983 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,39E-03 0,05474885 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 9,39E-03 0,0546185 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 9,39E-03 0,05448876 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 9,39E-03 0,05435964 ! response to mercury ion GO:0046689 8 5 0,000 9,39E-03 0,05423113 ! response to cadmium ion GO:0046686 7 5 0,000 9,39E-03 0,05410323 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 9,39E-03 0,05397593 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 9,39E-03 0,05384922 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 9,39E-03 0,05372311 ! bile acid biosynthetic process GO:0006699 7 5 0,000 9,39E-03 0,05359759 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 9,39E-03 0,05347266 ! ganglioside catabolic process GO:0006689 12 5 0,000 9,39E-03 0,0533483 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,39E-03 0,05322452 ! decidualization GO:0046697 11 5 0,000 9,39E-03 0,05310132 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 9,39E-03 0,05297868 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 9,39E-03 0,05285661 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 9,39E-03 0,0527351 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 9,39E-03 0,05261415 ! embryonic cleavage GO:0040016 6 5 0,000 9,39E-03 0,05249375 ! peroxisome fission GO:0016559 5 5 0,000 9,39E-03 0,0523739 ! histone demethylation GO:0016577 13 5 0,000 9,39E-03 0,0522546 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 9,39E-03 0,05213584 ! mitotic recombination GO:0006312 9 5 0,000 9,39E-03 0,05201762 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 9,39E-03 0,05189993 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,39E-03 0,05178277 ! metaphase plate congression GO:0051310 7 5 0,000 9,39E-03 0,05166615 ! regulation of sterol transport GO:0032371 7 5 0,000 9,39E-03 0,05155004 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,39E-03 0,05143446 ! enteric nervous system development GO:0048484 8 5 0,000 9,39E-03 0,05131939 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 9,39E-03 0,05120484 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 9,39E-03 0,0510908 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 9,39E-03 0,05097726 ! muscle cell proliferation GO:0033002 12 5 0,000 9,39E-03 0,05086423 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,39E-03 0,0507517 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 9,39E-03 0,05063967 ! B cell homeostasis GO:0001782 13 5 0,000 9,39E-03 0,05052813 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 9,39E-03 0,05041707 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,39E-03 0,05030651 ! metaphase GO:0051323 11 5 0,000 9,39E-03 0,05019643 ! melatonin biosynthetic process GO:0030187 7 5 0,000 9,39E-03 0,05008683 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 9,39E-03 0,04997771 ! cellular response to nutrient GO:0031670 8 5 0,000 9,39E-03 0,04986906 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,39E-03 0,04976089 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 9,39E-03 0,04965318 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 9,39E-03 0,04954594 ! regulation of hair follicle development GO:0051797 10 5 0,000 9,39E-03 0,04943916 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 9,39E-03 0,04933284 ! response to redox state GO:0051775 6 5 0,000 9,39E-03 0,04922697 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 9,39E-03 0,04912156 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 9,39E-03 0,0490166 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,39E-03 0,04891209 ! brown fat cell differentiation GO:0050873 7 5 0,000 9,39E-03 0,04880802 ! regulation of telomerase activity GO:0051972 7 5 0,000 9,39E-03 0,04870439 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,39E-03 0,04860121 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 9,39E-03 0,04849845 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,39E-03 0,04839614 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 9,39E-03 0,04829425 ! striatum development GO:0021756 14 5 0,000 9,39E-03 0,04819279 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 9,39E-03 0,04809176 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,39E-03 0,04799115 ! glial cell migration GO:0008347 10 5 0,000 9,39E-03 0,04789096 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,39E-03 0,04779119 ! neural plate morphogenesis GO:0001839 7 5 0,000 9,39E-03 0,04769183 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 9,39E-03 0,04759288 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,39E-03 0,04749435 ! T cell activation during immune response GO:0002286 9 5 0,000 9,39E-03 0,04739622 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,39E-03 0,04729849 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,39E-03 0,04720117 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 9,39E-03 0,04710425 ! neuroprotection GO:0043526 8 5 0,000 9,39E-03 0,04700772 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,39E-03 0,04691159 ! regulation of sensory perception GO:0051931 8 5 0,000 9,39E-03 0,04681586 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,39E-03 0,04672051 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,39E-03 0,04662555 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 9,39E-03 0,04653097 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 9,39E-03 0,04643678 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,39E-03 0,04634297 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 9,39E-03 0,04624953 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,39E-03 0,04615648 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 9,39E-03 0,04606379 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 9,39E-03 0,04597148 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,39E-03 0,04587954 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,39E-03 0,04578796 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,39E-03 0,04569675 ! protein palmitoylation GO:0018345 12 5 0,000 9,39E-03 0,0456059 ! drug metabolic process GO:0017144 7 5 0,000 9,39E-03 0,04551541 ! stem cell division GO:0017145 11 5 0,000 9,39E-03 0,04542529 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,39E-03 0,04533551 ! organ regeneration GO:0031100 7 5 0,000 9,39E-03 0,04524609 ! carnitine metabolic process GO:0009437 8 5 0,000 9,39E-03 0,04515703 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,39E-03 0,04506831 ! lipoprotein metabolic process GO:0042157 147 78 1,000 9,585E-03 0,04591358 ! steroid biosynthetic process GO:0006694 146 79 1,000 9,822E-03 0,04695722 ! protein oligomerization GO:0051259 149 79 1,000 9,822E-03 0,0468655 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,01006169 0,0479156 ! response to hypoxia GO:0001666 178 81 1,000 0,01030397 0,04897391 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01030397 0,04887881 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01054882 0,04994337 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,01079625 0,05101594 ! response to oxygen levels GO:0070482 183 83 1,000 0,01079625 0,05091745 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01079625 0,05081935 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01125755 0,05288884 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01125755 0,05278732 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01125755 0,0526862 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01125755 0,05258546 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01125755 0,0524851 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01125755 0,05238513 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01125755 0,05228554 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01125755 0,05218633 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01125755 0,05208749 ! response to oxygen radical GO:0000305 11 6 0,000 0,01125755 0,05198903 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01125755 0,05189093 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01125755 0,05179321 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01125755 0,05169585 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01125755 0,05159886 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01125755 0,05150224 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01125755 0,05140597 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01125755 0,05131006 ! forebrain regionalization GO:0021871 9 6 0,000 0,01125755 0,05121451 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01125755 0,05111932 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01125755 0,05102448 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01125755 0,05092999 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01125755 0,05083585 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01125755 0,05074206 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01125755 0,05064861 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01125755 0,0505555 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01125755 0,05046274 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01125755 0,05037032 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01125755 0,05027823 ! malate metabolic process GO:0006108 13 6 0,000 0,01125755 0,05018649 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01125755 0,05009507 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01125755 0,05000399 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01125755 0,04991324 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01125755 0,04982282 ! protein refolding GO:0042026 15 6 0,000 0,01125755 0,04973272 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01125755 0,04964295 ! opsonization GO:0008228 8 6 0,000 0,01125755 0,0495535 ! mating behavior GO:0007617 7 6 0,000 0,01125755 0,04946438 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01125755 0,04937557 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01125755 0,04928709 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01125755 0,04919892 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01125755 0,04911106 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01125755 0,04902352 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01125755 0,04893629 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01125755 0,04884937 ! toxin metabolic process GO:0009404 11 6 0,000 0,01125755 0,04876276 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01125755 0,04867645 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01125755 0,04859045 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01125755 0,04850475 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01125755 0,04841936 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01125755 0,04833426 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01125755 0,04824946 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01125755 0,04816496 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01125755 0,04808076 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01125755 0,04799685 ! thymic T cell selection GO:0045061 16 6 0,000 0,01125755 0,04791323 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01125755 0,0478299 ! protein lipoylation GO:0009249 10 6 0,000 0,01125755 0,04774687 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01125755 0,04766412 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01125755 0,04758165 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01125755 0,04749947 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01125755 0,04741758 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01125755 0,04733596 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01125755 0,04725463 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01125755 0,04717358 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01125755 0,0470928 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01125755 0,0470123 ! hyperosmotic response GO:0006972 10 6 0,000 0,01125755 0,04693207 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01125755 0,04685212 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01125755 0,04677244 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01125755 0,04669303 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01125755 0,04661389 ! urea metabolic process GO:0019627 7 6 0,000 0,01125755 0,04653502 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01125755 0,04645641 ! neutrophil activation GO:0042119 7 6 0,000 0,01125755 0,04637807 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01125755 0,04629999 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01125755 0,04622218 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01125755 0,04614462 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01125755 0,04606733 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01125755 0,04599029 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01125755 0,04591351 ! neuron apoptosis GO:0051402 15 6 0,000 0,01125755 0,04583699 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01125755 0,04576072 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01125755 0,04568471 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01125755 0,04560895 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01125755 0,04553343 ! carnitine transport GO:0015879 10 6 0,000 0,01125755 0,04545817 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01125755 0,04538316 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01125755 0,04530839 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01125755 0,04523387 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01125755 0,0451596 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01125755 0,04508556 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01125755 0,04501177 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01125755 0,04493823 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01125755 0,04486492 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01125755 0,04479185 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01125755 0,04471902 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01125755 0,04464642 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01125755 0,04457406 ! response to UV-C GO:0010225 14 6 0,000 0,01125755 0,04450193 ! astrocyte development GO:0014002 16 6 0,000 0,01125755 0,04443004 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01125755 0,04435838 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01125755 0,04428695 ! interaction with symbiont GO:0051702 14 6 0,000 0,01125755 0,04421575 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01125755 0,04414477 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01125755 0,04407403 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01125755 0,04400351 ! response to copper ion GO:0046688 10 6 0,000 0,01125755 0,04393322 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01125755 0,04386315 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01125755 0,0437933 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01125755 0,04372368 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01125755 0,04365428 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01125755 0,04358509 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01125755 0,04351613 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01125755 0,04344738 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01125755 0,04337886 ! hair follicle maturation GO:0048820 8 6 0,000 0,01125755 0,04331054 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01125755 0,04324244 ! Schwann cell development GO:0014044 15 6 0,000 0,01125755 0,04317456 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01125755 0,04310689 ! response to pheromone GO:0019236 6 6 0,000 0,01125755 0,04303943 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01125755 0,04297218 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01125755 0,04290514 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01125755 0,04283831 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01125755 0,04277169 ! subpallium development GO:0021544 15 6 0,000 0,01125755 0,04270527 ! neural tube patterning GO:0021532 8 6 0,000 0,01125755 0,04263906 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01125755 0,04257306 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01125755 0,04250726 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01125755 0,04244166 ! G2 phase GO:0051319 16 6 0,000 0,01125755 0,04237626 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01125755 0,04231107 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01125755 0,04224607 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01125755 0,04218128 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01125755 0,04211668 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01125755 0,04205229 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01125755 0,04198808 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01125755 0,04192408 ! receptor internalization GO:0031623 11 6 0,000 0,01125755 0,04186027 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01125755 0,04179665 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01125755 0,04173322 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01125755 0,04166999 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01125755 0,04160695 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01125755 0,0415441 ! protein deubiquitination GO:0016579 16 6 0,000 0,01125755 0,04148144 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01125755 0,04141897 ! protein destabilization GO:0031648 9 6 0,000 0,01125755 0,04135668 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01125755 0,04129459 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01125755 0,04123268 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01125755 0,04117095 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01125755 0,04110941 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01125755 0,04104805 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01125755 0,04098688 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01125755 0,04092588 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01125755 0,04086507 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01125755 0,04080444 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01125755 0,04074399 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01125755 0,04068372 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01125755 0,04062363 ! neural plate development GO:0001840 9 6 0,000 0,01125755 0,04056371 ! catecholamine transport GO:0051937 9 6 0,000 0,01125755 0,04050397 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01125755 0,0404444 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01125755 0,04038501 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01125755 0,0403258 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01125755 0,04026676 ! maternal placenta development GO:0001893 12 6 0,000 0,01125755 0,04020789 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01125755 0,04014919 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01125755 0,04009066 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01125755 0,04003231 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01125755 0,03997412 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01125755 0,0399161 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01125755 0,03985825 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01125755 0,03980057 GO:0055081|anion homeostasis, ! negative regulation of transport GO:0051051 164 85 1,000 0,01129877 0,03988857 ! negative regulation of growth GO:0045926 168 85 1,000 0,01129877 0,03983102 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,01129877 0,03977362 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,01155384 0,040613 ! regulation of lyase activity GO:0051339 169 86 1,000 0,01155384 0,04055464 ! mitochondrion organization GO:0007005 159 87 1,000 0,01181144 0,04139935 ! regulation of protein transport GO:0051223 165 87 1,000 0,01181144 0,04134004 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,01233418 0,04310787 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,01286691 0,04490552 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,01286691 0,04484146 ! gland development GO:0048732 220 91 1,000 0,01286691 0,04477758 ! tRNA transcription GO:0009304 17 7 0,000 0,01312163 0,04559907 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01312163 0,0455343 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01312163 0,04546971 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01312163 0,04540531 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01312163 0,04534108 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01312163 0,04527704 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01312163 0,04521318 ! sleep GO:0030431 16 7 0,000 0,01312163 0,0451495 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01312163 0,045086 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01312163 0,04502268 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01312163 0,04495953 ! prostate gland development GO:0030850 14 7 0,000 0,01312163 0,04489656 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01312163 0,04483377 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01312163 0,04477115 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01312163 0,04470871 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01312163 0,04464644 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01312163 0,04458435 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01312163 0,04452243 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01312163 0,04446067 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01312163 0,0443991 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01312163 0,04433769 ! glycolipid transport GO:0046836 11 7 0,000 0,01312163 0,04427645 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01312163 0,04421537 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01312163 0,04415447 ! neuron adhesion GO:0007158 14 7 0,000 0,01312163 0,04409374 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01312163 0,04403317 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01312163 0,04397277 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01312163 0,04391253 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01312163 0,04385246 ! mRNA stabilization GO:0048255 18 7 0,000 0,01312163 0,04379255 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01312163 0,04373281 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01312163 0,04367322 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01312163 0,0436138 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01312163 0,04355455 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01312163 0,04349545 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01312163 0,04343651 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01312163 0,04337774 ! lipoprotein transport GO:0042953 14 7 0,000 0,01312163 0,04331912 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01312163 0,04326066 ! rhythmic behavior GO:0007622 17 7 0,000 0,01312163 0,04320235 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01312163 0,04314421 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01312163 0,04308622 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01312163 0,04302838 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01312163 0,04297071 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01312163 0,04291318 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01312163 0,04285581 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01312163 0,04279859 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01312163 0,04274153 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01312163 0,04268462 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01312163 0,04262785 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01312163 0,04257124 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01312163 0,04251478 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01312163 0,04245847 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01312163 0,04240231 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01312163 0,0423463 ! spinal cord patterning GO:0021511 14 7 0,000 0,01312163 0,04229043 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01312163 0,04223471 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01312163 0,04217914 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01312163 0,04212371 ! adrenal gland development GO:0030325 17 7 0,000 0,01312163 0,04206843 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01312163 0,0420133 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01312163 0,04195831 ! ovulation GO:0030728 10 7 0,000 0,01312163 0,04190346 ! adenohypophysis development GO:0021984 11 7 0,000 0,01312163 0,04184876 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01312163 0,04179419 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01312163 0,04173977 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01312163 0,0416855 ! microtubule nucleation GO:0007020 21 7 0,000 0,01312163 0,04163136 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01312163 0,04157736 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01312163 0,04152351 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01312163 0,04146979 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01312163 0,04141621 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01312163 0,04136277 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01312163 0,04130947 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01312163 0,0412563 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01312163 0,04120327 ! galactose metabolic process GO:0006012 13 7 0,000 0,01312163 0,04115038 ! vesicle fusion GO:0006906 20 7 0,000 0,01312163 0,04109762 ! response to dietary excess GO:0002021 8 7 0,000 0,01312163 0,041045 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01312163 0,04099251 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01312163 0,04094016 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01312163 0,04088794 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01312163 0,04083586 ! organ growth GO:0035265 15 7 0,000 0,01312163 0,0407839 ! nucleoside transport GO:0015858 11 7 0,000 0,01312163 0,04073208 ! nucleoside salvage GO:0043174 11 7 0,000 0,01312163 0,04068039 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01312163 0,04062883 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01312163 0,0405774 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01312163 0,0405261 ! parturition GO:0007567 16 7 0,000 0,01312163 0,04047493 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01312163 0,04042389 ! rRNA modification GO:0000154 14 7 0,000 0,01312163 0,04037298 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01312163 0,0403222 ! spindle checkpoint GO:0031577 16 7 0,000 0,01312163 0,04027154 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01312163 0,04022101 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01312163 0,04017061 ! monocyte differentiation GO:0030224 16 7 0,000 0,01312163 0,04012033 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01312163 0,04007018 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01312163 0,04002016 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01312163 0,03997026 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01312163 0,03992048 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01312163 0,03987083 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01312163 0,0398213 ! fibrinolysis GO:0042730 11 7 0,000 0,01312163 0,03977189 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01312163 0,03972261 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01312163 0,03967345 ! eating behavior GO:0042755 8 7 0,000 0,01312163 0,03962441 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01312163 0,03957549 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01312163 0,03952669 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01312163 0,03947801 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01312163 0,03942945 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01312163 0,03938102 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01312163 0,0393327 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01312163 0,03928449 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01312163 0,03923641 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01312163 0,03918844 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01312163 0,03914059 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01312163 0,03909286 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01312163 0,03904525 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01312163 0,03899775 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01312163 0,03895036 ! histone ubiquitination GO:0016574 9 7 0,000 0,01312163 0,03890309 ! regulation of meiosis GO:0040020 12 7 0,000 0,01312163 0,03885594 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01312163 0,03880889 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01312163 0,03876197 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01312163 0,03871515 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01312163 0,03866845 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01312163 0,03862186 ! transcription termination GO:0006353 14 7 0,000 0,01312163 0,03857539 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01312163 0,03852902 ! anaphase GO:0051322 18 7 0,000 0,01312163 0,03848277 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01312163 0,03843663 ! axonal fasciculation GO:0007413 19 7 0,000 0,01312163 0,03839059 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01312163 0,03834467 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01312163 0,03829886 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01312163 0,03825316 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01312163 0,03820756 ! diuresis GO:0030146 12 7 0,000 0,01312163 0,03816208 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01312163 0,0381167 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01312163 0,03807143 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01312163 0,03802627 ! antibiotic transport GO:0042891 9 7 0,000 0,01312163 0,03798122 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01312163 0,03793627 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01312163 0,03789143 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01312163 0,03784669 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01312163 0,03780206 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01312163 0,03775753 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01312163 0,03771311 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01312163 0,0376688 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01312163 0,03762459 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01312163 0,03758048 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01312163 0,03753647 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01312163 0,03749257 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01312163 0,03744877 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01312163 0,03740507 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01312163 0,03736148 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01312163 0,03731798 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01312163 0,03727459 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01312163 0,0372313 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01312163 0,03718811 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01312163 0,03714501 ! muscle adaptation GO:0043500 13 7 0,000 0,01312163 0,03710202 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01312163 0,03705913 ! retina homeostasis GO:0001895 12 7 0,000 0,01312163 0,03701634 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01312163 0,03697364 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01312163 0,03693104 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01312163 0,03688855 ! bone development GO:0060348 206 92 1,000 0,013137 0,03688929 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,013137 0,03684694 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01368456 0,03833874 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,01396202 0,03907126 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,01396202 0,03902656 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01396202 0,03898196 ! regulation of T cell activation GO:0050863 175 96 1,000 0,01424191 0,03971803 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,01452424 0,04045919 ! regulation of protein localization GO:0032880 188 97 1,000 0,01452424 0,04041311 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01480898 0,04115852 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,01480898 0,04111174 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01498225 0,04154556 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01498225 0,04149846 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01498225 0,04145146 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01498225 0,04140457 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01498225 0,04135779 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01498225 0,04131111 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01498225 0,04126453 ! male meiosis GO:0007140 9 8 0,000 0,01498225 0,04121806 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01498225 0,0411717 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01498225 0,04112544 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01498225 0,04107928 ! meiotic prophase I GO:0007128 14 8 0,000 0,01498225 0,04103323 ! response to zinc ion GO:0010043 12 8 0,000 0,01498225 0,04098728 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01498225 0,04094143 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01498225 0,04089569 ! oligopeptide transport GO:0006857 16 8 0,000 0,01498225 0,04085005 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01498225 0,04080451 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01498225 0,04075907 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01498225 0,04071373 ! signal peptide processing GO:0006465 12 8 0,000 0,01498225 0,04066849 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01498225 0,04062335 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01498225 0,04057832 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01498225 0,04053338 ! succinate metabolic process GO:0006105 17 8 0,000 0,01498225 0,04048854 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01498225 0,0404438 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01498225 0,04039916 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01498225 0,04035462 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01498225 0,04031018 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01498225 0,04026583 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01498225 0,04022158 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01498225 0,04017743 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01498225 0,04013338 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01498225 0,04008942 ! reflex GO:0060004 17 8 0,000 0,01498225 0,04004556 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01498225 0,04000179 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01498225 0,03995812 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01498225 0,03991455 ! pigment granule organization GO:0048753 17 8 0,000 0,01498225 0,03987107 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01498225 0,03982768 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01498225 0,03978439 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01498225 0,0397412 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01498225 0,03969809 ! histidine catabolic process GO:0006548 10 8 0,000 0,01498225 0,03965508 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01498225 0,03961217 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01498225 0,03956934 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01498225 0,03952661 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01498225 0,03948397 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01498225 0,03944142 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01498225 0,03939897 ! melanin metabolic process GO:0006582 17 8 0,000 0,01498225 0,0393566 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01498225 0,03931433 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01498225 0,03927215 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01498225 0,03923005 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01498225 0,03918805 ! macrophage activation GO:0042116 13 8 0,000 0,01498225 0,03914614 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01498225 0,03910432 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01498225 0,03906258 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01498225 0,03902094 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01498225 0,03897938 ! purine salvage GO:0043101 12 8 0,000 0,01498225 0,03893792 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01498225 0,03889654 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01498225 0,03885525 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01498225 0,03881404 ! osteoblast development GO:0002076 17 8 0,000 0,01498225 0,03877292 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01498225 0,0387319 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01498225 0,03869095 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01498225 0,0386501 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01498225 0,03860933 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01498225 0,03856864 ! response to UV-B GO:0010224 17 8 0,000 0,01498225 0,03852804 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01498225 0,03848753 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01498225 0,0384471 ! intermediate filament organization GO:0045109 12 8 0,000 0,01498225 0,03840676 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01498225 0,0383665 ! cellular extravasation GO:0045123 13 8 0,000 0,01498225 0,03832633 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01498225 0,03828624 ! response to antibiotic GO:0046677 11 8 0,000 0,01498225 0,03824623 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01498225 0,03820631 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01498225 0,03816647 ! DNA topological change GO:0006265 12 8 0,000 0,01498225 0,03812671 ! response to tropane GO:0014073 15 8 0,000 0,01498225 0,03808704 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,01498225 0,03804744 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01498225 0,03800793 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01498225 0,03796851 ! mast cell activation GO:0045576 14 8 0,000 0,01498225 0,03792916 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01498225 0,0378899 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01498225 0,03785071 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01498225 0,03781161 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01498225 0,03777259 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01498225 0,03773365 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01498225 0,03769479 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01498225 0,03765601 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01498225 0,03761731 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01498225 0,03757869 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01498225 0,03754014 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01498225 0,03750168 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01498225 0,0374633 ! response to tumor cell GO:0002347 16 8 0,000 0,01498225 0,03742499 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01498225 0,03738676 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01498225 0,03734861 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01498225 0,03731054 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01498225 0,03727255 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01498225 0,03723463 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01498225 0,03719679 ! hormone catabolic process GO:0042447 17 8 0,000 0,01498225 0,03715903 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01498225 0,03712134 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01498225 0,03708373 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01498225 0,0370462 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01498225 0,03700874 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01498225 0,03697135 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01498225 0,03693405 ! adult feeding behavior GO:0008343 10 8 0,000 0,01498225 0,03689682 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01498225 0,03685966 ! ATP catabolic process GO:0006200 11 8 0,000 0,01498225 0,03682258 ! blastocyst growth GO:0001832 19 8 0,000 0,01498225 0,03678557 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01498225 0,03674864 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01498225 0,03671178 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01498225 0,03667499 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01498225 0,03663828 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01498225 0,03660164 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01498225 0,03656508 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01498225 0,03652858 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01498225 0,03649216 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01498225 0,03645582 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01498225 0,03641954 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01498225 0,03638334 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01498225 0,03634721 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01498225 0,03631115 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01498225 0,03627516 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01498225 0,03623925 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01498225 0,0362034 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01498225 0,03616763 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01498225 0,03613193 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01498225 0,03609629 ! axon extension GO:0048675 16 9 0,000 0,01683942 0,04053073 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01683942 0,04049084 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01683942 0,04045103 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01683942 0,04041129 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01683942 0,04037163 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01683942 0,04033205 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01683942 0,04029255 ! reproductive behavior GO:0019098 22 9 0,000 0,01683942 0,04025312 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01683942 0,04021378 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01683942 0,04017451 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01683942 0,04013531 ! UTP metabolic process GO:0046051 10 9 0,000 0,01683942 0,04009619 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01683942 0,04005715 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01683942 0,04001818 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01683942 0,03997929 ! artery development GO:0060840 25 9 0,000 0,01683942 0,03994048 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01683942 0,03990174 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01683942 0,03986308 ! equilibrioception GO:0050957 20 9 0,000 0,01683942 0,03982449 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01683942 0,03978597 ! chemosensory behavior GO:0007635 21 9 0,000 0,01683942 0,03974753 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01683942 0,03970916 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01683942 0,03967087 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01683942 0,03963265 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01683942 0,03959451 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01683942 0,03955644 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01683942 0,03951844 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01683942 0,03948051 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01683942 0,03944266 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01683942 0,03940488 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01683942 0,03936717 ! protein targeting to ER GO:0045047 25 9 0,000 0,01683942 0,03932953 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01683942 0,03929197 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01683942 0,03925448 ! T cell selection GO:0045058 27 9 0,000 0,01683942 0,03921706 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01683942 0,03917971 ! glycine catabolic process GO:0006546 15 9 0,000 0,01683942 0,03914243 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01683942 0,03910522 ! endosome organization GO:0007032 20 9 0,000 0,01683942 0,03906808 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01683942 0,03903102 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01683942 0,03899402 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01683942 0,0389571 ! mannose metabolic process GO:0006013 13 9 0,000 0,01683942 0,03892024 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01683942 0,03888345 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01683942 0,03884674 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01683942 0,03881009 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01683942 0,03877351 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01683942 0,038737 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01683942 0,03870056 ! retinol metabolic process GO:0042572 20 9 0,000 0,01683942 0,03866419 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01683942 0,03862788 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01683942 0,03859164 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01683942 0,03855548 ! macrophage differentiation GO:0030225 15 9 0,000 0,01683942 0,03851938 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01683942 0,03848334 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01683942 0,03844738 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01683942 0,03841148 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01683942 0,03837565 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01683942 0,03833988 ! response to amine stimulus GO:0014075 13 9 0,000 0,01683942 0,03830418 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01683942 0,03826855 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01683942 0,03823299 ! erythrocyte development GO:0048821 17 9 0,000 0,01683942 0,03819749 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01683942 0,03816205 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01683942 0,03812669 ! renal water homeostasis GO:0003091 15 9 0,000 0,01683942 0,03809138 ! postreplication repair GO:0006301 25 9 0,000 0,01683942 0,03805615 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01683942 0,03802097 ! icosanoid secretion GO:0032309 15 9 0,000 0,01683942 0,03798587 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01683942 0,03795082 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01683942 0,03791585 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01683942 0,03788093 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01683942 0,03784608 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01683942 0,0378113 ! sterol catabolic process GO:0016127 14 9 0,000 0,01683942 0,03777658 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01683942 0,03774192 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01683942 0,03770733 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01683942 0,0376728 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01683942 0,03763833 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01683942 0,03760392 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01683942 0,03756958 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01683942 0,0375353 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01683942 0,03750109 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01683942 0,03746693 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01683942 0,03743284 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01683942 0,03739881 ! purine base metabolic process GO:0006144 25 9 0,000 0,01683942 0,03736484 ! pigment granule transport GO:0051904 17 9 0,000 0,01683942 0,03733094 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01683942 0,03729709 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01683942 0,03726331 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01683942 0,03722959 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01683942 0,03719593 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01683942 0,03716232 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01683942 0,03712878 ! mitochondrion localization GO:0051646 18 9 0,000 0,01683942 0,03709531 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01869313 0,04114173 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01869313 0,0411047 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01869313 0,04106773 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01869313 0,04103083 ! associative learning GO:0008306 21 10 0,000 0,01869313 0,040994 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01869313 0,04095724 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01869313 0,04092054 ! phosphate transport GO:0006817 24 10 0,000 0,01869313 0,0408839 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01869313 0,04084733 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01869313 0,04081083 ! CTP metabolic process GO:0046036 11 10 0,000 0,01869313 0,04077439 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01869313 0,04073802 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01869313 0,04070171 ! GTP metabolic process GO:0046039 11 10 0,000 0,01869313 0,04066547 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01869313 0,04062929 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01869313 0,04059317 ! social behavior GO:0035176 29 10 0,000 0,01869313 0,04055712 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01869313 0,04052113 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01869313 0,04048521 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01869313 0,04044935 ! androgen metabolic process GO:0008209 17 10 0,000 0,01869313 0,04041356 ! phospholipid efflux GO:0033700 19 10 0,000 0,01869313 0,04037782 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01869313 0,04034215 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01869313 0,04030655 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01869313 0,040271 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01869313 0,04023552 ! pathogenesis GO:0009405 17 10 0,000 0,01869313 0,0402001 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01869313 0,04016475 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01869313 0,04012945 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01869313 0,04009422 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01869313 0,04005905 ! endoderm development GO:0007492 18 10 0,000 0,01869313 0,04002394 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01869313 0,0399889 ! arginine catabolic process GO:0006527 17 10 0,000 0,01869313 0,03995391 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01869313 0,03991899 ! proline metabolic process GO:0006560 13 10 0,000 0,01869313 0,03988412 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01869313 0,03984932 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01869313 0,03981458 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01869313 0,03977989 ! V(D)J recombination GO:0033151 34 10 0,000 0,01869313 0,03974527 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01869313 0,03971071 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01869313 0,03967621 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01869313 0,03964177 ! B cell proliferation GO:0042100 19 10 0,000 0,01869313 0,03960739 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01869313 0,03957307 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01869313 0,0395388 ! multicellular organism growth GO:0035264 19 10 0,000 0,01869313 0,0395046 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01869313 0,03947046 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01869313 0,03943637 ! ruffle organization GO:0031529 17 10 0,000 0,01869313 0,03940235 ! epithelial cell development GO:0002064 21 10 0,000 0,01869313 0,03936838 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01869313 0,03933447 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01869313 0,03930062 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01869313 0,03926683 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01869313 0,03923309 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01869313 0,03919942 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01869313 0,0391658 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01869313 0,03913224 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01869313 0,03909873 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01869313 0,03906529 ! brain morphogenesis GO:0048854 23 10 0,000 0,01869313 0,0390319 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01869313 0,03899856 ! segment specification GO:0007379 15 10 0,000 0,01869313 0,03896529 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01869313 0,03893207 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01869313 0,03889891 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01869313 0,0388658 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01869313 0,03883275 ! response to dsRNA GO:0043331 23 10 0,000 0,01869313 0,03879976 ! DNA ligation GO:0006266 18 10 0,000 0,01869313 0,03876682 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01869313 0,03873394 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01869313 0,03870112 ! melanosome localization GO:0032400 16 10 0,000 0,01869313 0,03866835 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01869313 0,03863563 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01869313 0,03860297 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01869313 0,03857037 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01869313 0,03853782 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01869313 0,03850533 ! induction of an organ GO:0001759 17 10 0,000 0,01869313 0,03847289 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01869313 0,0384405 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01869313 0,03840817 ! protein sumoylation GO:0016925 17 10 0,000 0,01869313 0,0383759 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01869313 0,03834368 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01869313 0,03831151 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01869313 0,0382794 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01869313 0,03824734 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01869313 0,03821533 ! salivary gland development GO:0007431 28 10 0,000 0,01869313 0,03818338 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01869313 0,03815148 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01869313 0,03811963 ! midbrain development GO:0030901 14 10 0,000 0,01869313 0,03808784 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01869313 0,0380561 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01869313 0,03802441 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01869313 0,03799278 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01869313 0,0379612 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01869313 0,03792967 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01869313 0,03789819 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01869313 0,03786677 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01869313 0,03783539 ! detection of calcium ion GO:0005513 24 10 0,000 0,01869313 0,03780407 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01869313 0,0377728 ! blastocyst formation GO:0001825 18 10 0,000 0,01869313 0,03774159 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01869313 0,03771042 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01869313 0,03767931 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01869313 0,03764824 ! response to nicotine GO:0035094 20 10 0,000 0,01869313 0,03761723 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01869313 0,03758627 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01869313 0,03755536 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0205434 0,04123873 ! respiratory burst GO:0045730 17 11 0,000 0,0205434 0,04120487 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0205434 0,04117107 ! neuron fate specification GO:0048665 18 11 0,000 0,0205434 0,04113732 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0205434 0,04110363 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0205434 0,04106999 ! thyroid gland development GO:0030878 26 11 0,000 0,0205434 0,04103641 ! synapsis GO:0007129 14 11 0,000 0,0205434 0,04100289 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0205434 0,04096941 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0205434 0,040936 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,0205434 0,04090263 ! response to pain GO:0048265 27 11 0,000 0,0205434 0,04086933 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0205434 0,04083607 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0205434 0,04080287 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0205434 0,04076973 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0205434 0,04073663 ! bone resorption GO:0045453 16 11 0,000 0,0205434 0,0407036 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0205434 0,04067061 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,0205434 0,04063768 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0205434 0,0406048 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0205434 0,04057198 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0205434 0,0405392 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0205434 0,04050648 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0205434 0,04047382 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0205434 0,0404412 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0205434 0,04040864 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,0205434 0,04037613 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0205434 0,04034368 ! UV protection GO:0009650 20 11 0,000 0,0205434 0,04031127 ! adult heart development GO:0007512 16 11 0,000 0,0205434 0,04027892 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0205434 0,04024662 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0205434 0,04021437 ! macroautophagy GO:0016236 19 11 0,000 0,0205434 0,04018217 ! temperature homeostasis GO:0001659 18 11 0,000 0,0205434 0,04015003 ! behavioral fear response GO:0001662 27 11 0,000 0,0205434 0,04011793 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0205434 0,04008589 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0205434 0,0400539 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0205434 0,04002196 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0205434 0,03999007 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0205434 0,03995823 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0205434 0,03992644 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0205434 0,0398947 ! regulation of organ growth GO:0046620 14 11 0,000 0,0205434 0,03986301 ! pigment granule localization GO:0051875 20 11 0,000 0,0205434 0,03983138 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0205434 0,03979979 ! vasoconstriction GO:0042310 20 11 0,000 0,0205434 0,03976825 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0205434 0,03973676 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0205434 0,03970533 ! embryonic axis specification GO:0000578 19 11 0,000 0,0205434 0,03967394 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0205434 0,0396426 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0205434 0,03961131 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0205434 0,03958007 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0205434 0,03954888 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0205434 0,03951774 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0205434 0,03948665 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0205434 0,03945561 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0205434 0,03942461 ! prophase GO:0051324 17 11 0,000 0,0205434 0,03939367 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0205434 0,03936277 ! nucleosome positioning GO:0016584 15 11 0,000 0,0205434 0,03933192 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0205434 0,03930112 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0205434 0,03927037 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0205434 0,03923967 ! apical protein localization GO:0045176 18 11 0,000 0,0205434 0,03920901 ! acid secretion GO:0046717 20 11 0,000 0,0205434 0,0391784 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0205434 0,03914784 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0205434 0,03911733 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0205434 0,03908686 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0205434 0,03905645 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0205434 0,03902608 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0205434 0,03899575 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0205434 0,03896548 ! cholesterol efflux GO:0033344 21 11 0,000 0,0205434 0,03893525 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0205434 0,03890506 ! oocyte development GO:0048599 20 11 0,000 0,0205434 0,03887493 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0205434 0,03884484 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0205434 0,0388148 ! embryonic gut development GO:0048566 19 11 0,000 0,0205434 0,0387848 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0205434 0,03875485 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0205434 0,03872495 ! activation of innate immune response GO:0002218 16 11 0,000 0,0205434 0,03869509 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0205434 0,03866528 ! lysogeny GO:0030069 22 11 0,000 0,0205434 0,03863551 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0205434 0,03860579 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0205434 0,03857612 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0205434 0,03854649 ! nucleus localization GO:0051647 22 11 0,000 0,0205434 0,03851691 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02239024 0,04194736 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02239024 0,04191521 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02239024 0,04188312 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02239024 0,04185107 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02239024 0,04181908 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02239024 0,04178713 ! protein complex disassembly GO:0043241 28 12 0,000 0,02239024 0,04175523 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02239024 0,04172338 ! hippocampus development GO:0021766 29 12 0,000 0,02239024 0,04169158 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02239024 0,04165983 ! T cell proliferation GO:0042098 32 12 0,000 0,02239024 0,04162812 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02239024 0,04159646 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02239024 0,04156486 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02239024 0,0415333 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02239024 0,04150178 ! drug transport GO:0015893 16 12 0,000 0,02239024 0,04147032 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02239024 0,0414389 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02239024 0,04140753 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02239024 0,04137621 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02239024 0,04134494 ! focal adhesion formation GO:0048041 37 12 0,000 0,02239024 0,04131371 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02239024 0,04128253 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02239024 0,0412514 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02239024 0,04122031 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02239024 0,04118927 ! lipid digestion GO:0044241 21 12 0,000 0,02239024 0,04115828 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02239024 0,04112733 ! entry into host cell GO:0030260 34 12 0,000 0,02239024 0,04109643 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02239024 0,04106558 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02239024 0,04103477 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02239024 0,04100401 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02239024 0,0409733 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02239024 0,04094263 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02239024 0,04091201 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02239024 0,04088143 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02239024 0,0408509 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02239024 0,04082041 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02239024 0,04078997 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02239024 0,04075958 ! cranial nerve development GO:0021545 23 12 0,000 0,02239024 0,04072923 ! fucose catabolic process GO:0019317 25 12 0,000 0,02239024 0,04069892 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02239024 0,04066866 ! histone acetylation GO:0016573 27 12 0,000 0,02239024 0,04063845 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02239024 0,04060828 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02239024 0,04057815 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02239024 0,04054807 ! zymogen activation GO:0031638 18 12 0,000 0,02239024 0,04051804 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02239024 0,04048805 ! T cell homeostasis GO:0043029 28 12 0,000 0,02239024 0,0404581 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02239024 0,0404282 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02239024 0,04039834 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02239024 0,04036852 ! oocyte differentiation GO:0009994 21 12 0,000 0,02239024 0,04033875 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02239024 0,04030903 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02239024 0,04027935 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02239024 0,04024971 ! defense response to fungus GO:0050832 15 12 0,000 0,02239024 0,04022011 ! developmental induction GO:0031128 22 12 0,000 0,02239024 0,04019056 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02239024 0,04016105 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02239024 0,04013159 ! response to cold GO:0009409 17 12 0,000 0,02239024 0,04010216 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02239024 0,04007278 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02239024 0,04004345 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02423364 0,04330855 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02423364 0,04327689 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02423364 0,04324528 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02423364 0,04321371 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02423364 0,04318219 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02423364 0,04315072 ! peroxisomal transport GO:0043574 28 13 0,000 0,02423364 0,04311929 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02423364 0,04308791 ! cartilage condensation GO:0001502 22 13 0,000 0,02423364 0,04305657 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02423364 0,04302528 ! organelle fusion GO:0048284 36 13 0,000 0,02423364 0,04299404 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02423364 0,04296284 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02423364 0,04293168 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02423364 0,04290057 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02423364 0,04286951 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02423364 0,04283849 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02423364 0,04280751 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02423364 0,04277658 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02423364 0,0427457 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02423364 0,04271485 ! methionine metabolic process GO:0006555 31 13 0,000 0,02423364 0,04268406 ! plasma membrane organization GO:0007009 27 13 0,000 0,02423364 0,04265331 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02423364 0,0426226 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02423364 0,04259193 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02423364 0,04256131 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02423364 0,04253074 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02423364 0,04250021 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02423364 0,04246972 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02423364 0,04243928 ! exocrine system development GO:0035272 34 13 0,000 0,02423364 0,04240887 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02423364 0,04237852 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02423364 0,0423482 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02423364 0,04231793 ! L-glutamate transport GO:0015813 30 13 0,000 0,02423364 0,04228771 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02423364 0,04225752 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02423364 0,04222738 ! protein homotetramerization GO:0051289 24 13 0,000 0,02423364 0,04219728 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02423364 0,04216723 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02423364 0,04213722 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02423364 0,04210725 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02423364 0,04207732 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02423364 0,04204744 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02423364 0,04201759 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02423364 0,04198779 ! histone methylation GO:0016571 29 13 0,000 0,02423364 0,04195804 ! chromatin silencing GO:0006342 29 13 0,000 0,02423364 0,04192832 ! gland morphogenesis GO:0022612 31 13 0,000 0,02423364 0,04189865 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02423364 0,04186902 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02423364 0,04183943 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02423364 0,04180988 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02423364 0,04178037 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02423364 0,04175091 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02423364 0,04172149 ! spleen development GO:0048536 24 13 0,000 0,02423364 0,0416921 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02423364 0,04166276 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02423364 0,04163347 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02423364 0,04160421 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02423364 0,04157499 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02423364 0,04154582 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02423364 0,04151668 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02423364 0,04148759 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02423364 0,04145854 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02423364 0,04142952 ! insulin secretion GO:0030073 24 13 0,000 0,02423364 0,04140055 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02423364 0,04137162 ! acrosome reaction GO:0007340 19 13 0,000 0,02423364 0,04134273 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02423364 0,04131388 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02423364 0,04128507 ! rRNA transcription GO:0009303 28 14 0,000 0,02607362 0,04438875 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02607362 0,04435784 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02607362 0,04432697 ! water transport GO:0006833 21 14 0,000 0,02607362 0,04429615 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02607362 0,04426537 ! non-recombinational repair GO:0000726 29 14 0,000 0,02607362 0,04423463 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02607362 0,04420393 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02607362 0,04417327 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02607362 0,04414266 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02607362 0,04411209 ! lipid localization GO:0010876 32 14 0,000 0,02607362 0,04408156 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02607362 0,04405108 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02607362 0,04402064 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02607362 0,04399024 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02607362 0,04395988 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02607362 0,04392956 ! arginine metabolic process GO:0006525 21 14 0,000 0,02607362 0,04389928 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02607362 0,04386905 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02607362 0,04383886 ! regulation of heart rate GO:0002027 25 14 0,000 0,02607362 0,04380871 ! fear response GO:0042596 34 14 0,000 0,02607362 0,0437786 ! organic alcohol transport GO:0015850 29 14 0,000 0,02607362 0,04374853 ! embryo implantation GO:0007566 30 14 0,000 0,02607362 0,0437185 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02607362 0,04368852 ! bone mineralization GO:0030282 18 14 0,000 0,02607362 0,04365858 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02607362 0,04362867 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02607362 0,04359881 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02607362 0,04356899 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02607362 0,04353921 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02607362 0,04350947 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02607362 0,04347977 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02607362 0,04345011 ! ribosome assembly GO:0042255 18 14 0,000 0,02607362 0,04342049 ! cerebellum development GO:0021549 23 14 0,000 0,02607362 0,04339091 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02607362 0,04336138 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02607362 0,04333188 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02607362 0,04330242 ! response to gamma radiation GO:0010332 30 14 0,000 0,02607362 0,043273 ! NADP metabolic process GO:0006739 24 14 0,000 0,02607362 0,04324363 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02607362 0,04321429 ! oxygen transport GO:0015671 22 14 0,000 0,02607362 0,04318499 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02607362 0,04315573 ! male genitalia development GO:0030539 26 14 0,000 0,02607362 0,04312651 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02607362 0,04309733 ! regulation of axon extension GO:0030516 43 14 0,000 0,02607362 0,0430682 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02607362 0,0430391 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02607362 0,04301003 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02791019 0,04600849 ! lactation GO:0007595 30 15 0,000 0,02791019 0,04597747 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02791019 0,04594648 ! reproductive cellular process GO:0048610 22 15 0,000 0,02791019 0,04591554 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02791019 0,04588465 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02791019 0,04585379 ! superoxide anion generation GO:0042554 22 15 0,000 0,02791019 0,04582297 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02791019 0,0457922 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02791019 0,04576147 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02791019 0,04573077 ! copper ion transport GO:0006825 22 15 0,000 0,02791019 0,04570012 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02791019 0,04566951 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02791019 0,04563894 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02791019 0,04560842 ! sulfate transport GO:0008272 27 15 0,000 0,02791019 0,04557793 ! response to cAMP GO:0051591 25 15 0,000 0,02791019 0,04554748 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02791019 0,04551708 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02791019 0,04548671 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02791019 0,04545639 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02791019 0,0454261 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02791019 0,04539586 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02791019 0,04536566 ! vesicle coating GO:0006901 38 15 0,000 0,02791019 0,04533549 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02791019 0,04530537 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02791019 0,04527529 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02791019 0,04524524 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02791019 0,04521524 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02791019 0,04518528 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02791019 0,04515535 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02791019 0,04512547 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02791019 0,04509562 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02791019 0,04506582 ! histone deacetylation GO:0016575 24 15 0,000 0,02791019 0,04503605 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02791019 0,04500633 ! water homeostasis GO:0030104 28 15 0,000 0,02791019 0,04497664 ! cofactor transport GO:0051181 30 15 0,000 0,02791019 0,04494699 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02791019 0,04491738 ! muscle maintenance GO:0046716 26 15 0,000 0,02791019 0,04488781 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02791019 0,04485828 ! intestinal absorption GO:0050892 31 15 0,000 0,02791019 0,04482879 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02791019 0,04479933 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02791019 0,04476992 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02791019 0,04474054 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02791019 0,0447112 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02791019 0,0446819 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02791019 0,04465264 ! actin filament polymerization GO:0030041 27 15 0,000 0,02791019 0,04462342 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02791019 0,04459423 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02974334 0,04749214 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02974334 0,04746112 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02974334 0,04743014 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02974334 0,0473992 ! bone remodeling GO:0046849 28 16 0,000 0,02974334 0,0473683 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02974334 0,04733744 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02974334 0,04730662 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02974334 0,04727584 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02974334 0,0472451 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02974334 0,04721441 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02974334 0,04718375 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02974334 0,04715313 ! startle response GO:0001964 28 16 0,000 0,02974334 0,04712255 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02974334 0,04709201 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02974334 0,04706151 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02974334 0,04703105 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02974334 0,04700063 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02974334 0,04697025 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02974334 0,0469399 ! pituitary gland development GO:0021983 30 16 0,000 0,02974334 0,0469096 ! response to osmotic stress GO:0006970 27 16 0,000 0,02974334 0,04687934 ! lysosomal transport GO:0007041 31 16 0,000 0,02974334 0,04684911 ! fructose metabolic process GO:0006000 25 16 0,000 0,02974334 0,04681892 ! L-amino acid transport GO:0015807 33 16 0,000 0,02974334 0,04678878 ! stem cell development GO:0048864 46 16 0,000 0,02974334 0,04675867 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02974334 0,0467286 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02974334 0,04669857 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02974334 0,04666857 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02974334 0,04663862 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02974334 0,0466087 ! axon cargo transport GO:0008088 46 16 0,000 0,02974334 0,04657883 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02974334 0,04654899 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02974334 0,04651919 ! DNA replication initiation GO:0006270 28 16 0,000 0,02974334 0,04648942 ! neuron recognition GO:0008038 40 16 0,000 0,02974334 0,0464597 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02974334 0,04643001 ! tissue regeneration GO:0042246 27 16 0,000 0,02974334 0,04640036 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02974334 0,04637075 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02974334 0,04634118 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02974334 0,04631164 ! biomineral formation GO:0031214 22 16 0,000 0,02974334 0,04628215 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02974334 0,04625269 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02974334 0,04622326 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02974334 0,04619388 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02974334 0,04616453 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02974334 0,04613522 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02974334 0,04610595 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02974334 0,04607671 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02974334 0,04604751 ! peptide hormone processing GO:0016486 27 16 0,000 0,02974334 0,04601835 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03157308 0,04881838 ! metencephalon development GO:0022037 32 17 0,000 0,03157308 0,0487875 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03157308 0,04875666 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03157308 0,04872586 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03157308 0,0486951 ! filopodium assembly GO:0046847 42 17 0,000 0,03157308 0,04866438 ! endothelial cell migration GO:0043542 31 17 0,000 0,03157308 0,04863369 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03157308 0,04860305 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03157308 0,04857244 ! glial cell development GO:0021782 28 17 0,000 0,03157308 0,04854187 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03157308 0,04851135 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03157308 0,04848085 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03157308 0,0484504 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03157308 0,04841999 ! myoblast differentiation GO:0045445 50 17 0,000 0,03157308 0,04838961 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03157308 0,04835927 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03157308 0,04832897 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03157308 0,04829871 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03157308 0,04826849 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03157308 0,0482383 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03157308 0,04820815 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03157308 0,04817804 ! NAD metabolic process GO:0019674 33 17 0,000 0,03157308 0,04814796 ! membrane budding GO:0006900 42 17 0,000 0,03157308 0,04811793 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03157308 0,04808793 ! regulation of protein binding GO:0043393 33 17 0,000 0,03157308 0,04805797 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03157308 0,04802804 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03157308 0,04799816 ! genitalia development GO:0048806 32 17 0,000 0,03157308 0,04796831 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03157308 0,0479385 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03157308 0,04790872 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03157308 0,04787898 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03157308 0,04784928 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03157308 0,04781962 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03157308 0,04778999 ! steroid catabolic process GO:0006706 34 17 0,000 0,03157308 0,0477604 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03157308 0,04773084 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03157308 0,04770132 ! gas transport GO:0015669 26 17 0,000 0,03157308 0,04767184 ! organic cation transport GO:0015695 32 17 0,000 0,03157308 0,0476424 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03157308 0,04761299 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03157308 0,04758361 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03157308 0,04755428 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03339943 0,05027406 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03339943 0,05024311 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03339943 0,05021219 ! limbic system development GO:0021761 40 18 0,000 0,03339943 0,05018131 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03339943 0,05015046 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03339943 0,05011966 ! adult walking behavior GO:0007628 36 18 0,000 0,03339943 0,05008889 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03339943 0,05005816 ! heart looping GO:0001947 34 18 0,000 0,03339943 0,05002747 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03339943 0,04999682 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03339943 0,0499662 ! centrosome cycle GO:0007098 26 18 0,000 0,03339943 0,04993562 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03339943 0,04990508 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03339943 0,04987457 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03339943 0,04984411 ! glycine metabolic process GO:0006544 30 18 0,000 0,03339943 0,04981368 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03339943 0,04978328 ! response to retinoic acid GO:0032526 31 18 0,000 0,03339943 0,04975293 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03339943 0,04972261 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03339943 0,04969233 ! DNA integration GO:0015074 32 18 0,000 0,03339943 0,04966208 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03339943 0,04963188 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03339943 0,0496017 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03339943 0,04957157 ! neural crest cell migration GO:0001755 41 18 0,000 0,03339943 0,04954147 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03339943 0,04951141 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03339943 0,04948138 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03339943 0,0494514 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03339943 0,04942144 ! detection of bacterium GO:0016045 22 18 0,000 0,03339943 0,04939153 ! nerve development GO:0021675 34 18 0,000 0,03339943 0,04936165 ! defense response to virus GO:0051607 43 18 0,000 0,03339943 0,0493318 ! microspike assembly GO:0030035 46 18 0,000 0,03339943 0,049302 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03339943 0,04927222 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03522238 0,05193016 ! positive regulation of translation GO:0045727 31 19 0,000 0,03522238 0,05189884 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03522238 0,05186756 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03522238 0,05183631 ! neuron maturation GO:0042551 46 19 0,000 0,03522238 0,0518051 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03522238 0,05177393 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03522238 0,0517428 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03522238 0,05171171 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03522238 0,05168065 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03522238 0,05164963 ! inositol metabolic process GO:0006020 33 19 0,000 0,03522238 0,05161864 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03522238 0,0515877 ! memory GO:0007613 34 19 0,000 0,03522238 0,05155679 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03522238 0,05152591 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03522238 0,05149508 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03522238 0,05146428 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03522238 0,05143352 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03522238 0,05140279 ! cerebral cortex development GO:0021987 40 19 0,000 0,03522238 0,05137211 ! pigmentation during development GO:0048066 42 19 0,000 0,03522238 0,05134145 ! response to vitamin A GO:0033189 32 19 0,000 0,03522238 0,05131084 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03522238 0,05128026 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03522238 0,05124972 ! response to fungus GO:0009620 26 19 0,000 0,03522238 0,05121921 ! peptide cross-linking GO:0018149 39 19 0,000 0,03522238 0,05118874 ! protein export from nucleus GO:0006611 40 19 0,000 0,03522238 0,05115831 ! heart process GO:0003015 32 19 0,000 0,03522238 0,05112791 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03522238 0,05109755 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03522238 0,05106723 ! visual learning GO:0008542 38 19 0,000 0,03522238 0,05103694 ! cellular pigmentation GO:0033059 37 19 0,000 0,03522238 0,05100669 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03522238 0,05097647 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03522238 0,05094629 ! vitamin transport GO:0051180 31 19 0,000 0,03522238 0,05091614 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03522238 0,05088603 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03522238 0,05085596 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03522238 0,05082592 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03522238 0,05079591 ! cilium assembly GO:0042384 38 19 0,000 0,03522238 0,05076595 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03522238 0,05073601 ! protein secretion GO:0009306 45 20 0,000 0,03704195 0,05332556 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03704195 0,05329416 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03704195 0,05326279 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03704195 0,05323146 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03704195 0,05320016 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,03704195 0,05316891 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03704195 0,05313769 ! response to vitamin GO:0033273 36 20 0,000 0,03704195 0,0531065 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03704195 0,05307535 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03704195 0,05304424 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03704195 0,05301317 ! response to alkaloid GO:0043279 38 20 0,000 0,03704195 0,05298213 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03704195 0,05295113 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03704195 0,05292016 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03704195 0,05288923 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03704195 0,05285834 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03704195 0,05282748 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03704195 0,05279666 ! actin filament bundle formation GO:0051017 47 20 0,000 0,03704195 0,05276588 ! body fluid secretion GO:0007589 33 20 0,000 0,03704195 0,05273513 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03704195 0,05270441 ! peptide secretion GO:0002790 38 20 0,000 0,03704195 0,05267374 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03704195 0,05264309 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,03704195 0,05261249 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03704195 0,05258192 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03704195 0,05255138 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03704195 0,05252088 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03704195 0,05249042 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03704195 0,05245999 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03704195 0,05242959 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03704195 0,05239924 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03704195 0,05236891 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03704195 0,05233862 ! regulation of glucose import GO:0046324 30 20 0,000 0,03704195 0,05230837 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03704195 0,05227815 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03704195 0,05224797 ! negative regulation of translation GO:0017148 32 20 0,000 0,03704195 0,05221782 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03704195 0,0521877 ! regulation of cell killing GO:0031341 46 21 0,000 0,03885813 0,05471494 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03885813 0,05468342 ! hormone secretion GO:0046879 39 21 0,000 0,03885813 0,05465194 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03885813 0,0546205 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03885813 0,05458909 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03885813 0,05455771 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03885813 0,05452638 ! ovarian follicle development GO:0001541 39 21 0,000 0,03885813 0,05449508 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03885813 0,05446381 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03885813 0,05443258 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03885813 0,05440139 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03885813 0,05437023 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03885813 0,05433911 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03885813 0,05430802 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03885813 0,05427697 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,03885813 0,05424595 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03885813 0,05421497 ! diencephalon development GO:0021536 36 21 0,000 0,03885813 0,05418403 ! collagen fibril organization GO:0030199 62 21 0,000 0,03885813 0,05415312 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03885813 0,05412225 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03885813 0,05409141 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03885813 0,0540606 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03885813 0,05402984 ! collagen catabolic process GO:0030574 29 21 0,000 0,03885813 0,0539991 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03885813 0,0539684 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03885813 0,05393774 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03885813 0,05390711 ! actin filament-based movement GO:0030048 47 21 0,000 0,03885813 0,05387652 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03885813 0,05384596 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04067095 0,05632603 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04067095 0,05629412 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04067095 0,05626224 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04067095 0,0562304 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04067095 0,0561986 ! microtubule-based transport GO:0010970 59 22 0,000 0,04067095 0,05616683 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04067095 0,0561351 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04067095 0,0561034 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,04067095 0,05607174 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04067095 0,05604011 ! cellular response to starvation GO:0009267 37 22 0,000 0,04067095 0,05600852 ! vacuolar transport GO:0007034 41 22 0,000 0,04067095 0,05597697 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04067095 0,05594545 ! fucose metabolic process GO:0006004 44 22 0,000 0,04067095 0,05591397 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04067095 0,05588252 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04067095 0,05585111 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04067095 0,05581973 ! cell aging GO:0007569 48 22 0,000 0,04067095 0,05578839 ! stem cell differentiation GO:0048863 57 22 0,000 0,04067095 0,05575708 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04067095 0,05572581 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04067095 0,05569457 ! cytolysis GO:0019835 27 22 0,000 0,04067095 0,05566337 ! renal system process GO:0003014 42 22 0,000 0,04067095 0,05563221 ! vasodilation GO:0042311 40 22 0,000 0,04067095 0,05560107 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04067095 0,05556998 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04067095 0,05553892 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04067095 0,05550789 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04067095 0,0554769 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04067095 0,05544594 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04067095 0,05541501 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04067095 0,05538412 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04067095 0,05535327 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04067095 0,05532245 ! sarcomere organization GO:0045214 32 22 0,000 0,04067095 0,05529166 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,04067095 0,05526091 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04067095 0,05523019 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04067095 0,05519951 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04067095 0,05516886 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04067095 0,05513825 ! gut development GO:0048565 44 22 0,000 0,04067095 0,05510766 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04067095 0,05507712 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04067095 0,0550466 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04067095 0,05501612 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04248039 0,05743198 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04248039 0,05740022 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04248039 0,05736849 ! gluconeogenesis GO:0006094 38 23 0,000 0,04248039 0,05733679 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04248039 0,05730513 ! viral genome replication GO:0019079 44 23 0,000 0,04248039 0,0572735 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04248039 0,05724191 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04248039 0,05721036 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04248039 0,05717884 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04248039 0,05714735 ! regeneration GO:0031099 42 23 0,000 0,04248039 0,0571159 ! axis specification GO:0009798 43 23 0,000 0,04248039 0,05708448 ! visual behavior GO:0007632 46 23 0,000 0,04248039 0,0570531 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04248039 0,05702175 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04248039 0,05699044 ! response to ethanol GO:0045471 47 23 0,000 0,04248039 0,05695916 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04248039 0,05692792 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04248039 0,0568967 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04248039 0,05686553 ! peroxisome organization GO:0007031 43 23 0,000 0,04248039 0,05683439 ! lysosome organization GO:0007040 47 23 0,000 0,04248039 0,05680328 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04248039 0,0567722 ! vesicle targeting GO:0006903 49 23 0,000 0,04248039 0,05674116 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04248039 0,05671016 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04248039 0,05667919 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04248039 0,05664825 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04248039 0,05661734 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04248039 0,05658647 ! DNA modification GO:0006304 36 23 0,000 0,04248039 0,05655563 ! fatty acid transport GO:0015908 47 23 0,000 0,04248039 0,05652483 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04248039 0,05649406 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04248039 0,05646332 ! hormone transport GO:0009914 41 23 0,000 0,04248039 0,05643262 ! cell-cell recognition GO:0009988 28 23 0,000 0,04248039 0,05640195 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04248039 0,05637131 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04248039 0,05634071 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04248039 0,05631014 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,04428647 0,05867237 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,04428647 0,05864057 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,04428647 0,0586088 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,04428647 0,05857707 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,04428647 0,05854537 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,04428647 0,05851371 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,04428647 0,05848208 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,04428647 0,05845048 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,04428647 0,05841892 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,04428647 0,0583874 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,04428647 0,0583559 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,04428647 0,05832445 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,04428647 0,05829302 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,04428647 0,05826163 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,04428647 0,05823027 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,04428647 0,05819895 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,04428647 0,05816766 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,04428647 0,0581364 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,04428647 0,05810518 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,04428647 0,05807399 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,04428647 0,05804284 ! membrane depolarization GO:0051899 45 24 0,000 0,04428647 0,05801171 ! pallium development GO:0021543 56 24 0,000 0,04428647 0,05798063 ! oogenesis GO:0048477 44 24 0,000 0,04428647 0,05794957 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,04428647 0,05791855 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,04428647 0,05788756 ! platelet activation GO:0030168 41 24 0,000 0,04428647 0,0578566 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,04428647 0,05782568 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,04428647 0,05779479 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,04428647 0,05776393 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,04428647 0,05773311 ! regulation of amine transport GO:0051952 41 24 0,000 0,04428647 0,05770232 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0460892 0,06001914 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0460892 0,05998716 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0460892 0,05995522 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0460892 0,05992331 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0460892 0,05989144 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0460892 0,0598596 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0460892 0,05982779 ! phototransduction GO:0007602 37 25 0,000 0,0460892 0,05979602 ! keratinization GO:0031424 37 25 0,000 0,0460892 0,05976428 ! vasculogenesis GO:0001570 49 25 0,000 0,0460892 0,05973258 ! vacuole organization GO:0007033 49 25 0,000 0,0460892 0,0597009 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0460892 0,05966927 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0460892 0,05963766 ! chromosome condensation GO:0030261 48 25 0,000 0,0460892 0,05960609 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0460892 0,05957455 ! regulation of behavior GO:0050795 48 25 0,000 0,0460892 0,05954305 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0460892 0,05951158 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0460892 0,05948014 ! immunoglobulin production GO:0002377 62 25 0,000 0,0460892 0,05944874 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0460892 0,05941736 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0460892 0,05938603 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0460892 0,05935472 ! liver development GO:0001889 55 25 0,000 0,0460892 0,05932345 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04788857 0,06160705 ! initiation of viral infection GO:0019059 60 26 0,000 0,04788857 0,06157462 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04788857 0,06154223 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04788857 0,06150987 ! molting cycle process GO:0022404 52 26 0,000 0,04788857 0,06147755 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,04788857 0,06144526 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04788857 0,06141301 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04788857 0,06138079 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04788857 0,0613486 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,04788857 0,06131645 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04788857 0,06128433 ! digestive system process GO:0022600 49 26 0,000 0,04788857 0,06125224 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04788857 0,06122019 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,04788857 0,06118817 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,04788857 0,06115618 ! osteoblast differentiation GO:0001649 63 26 0,000 0,04788857 0,06112423 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,04788857 0,06109231 ! neural crest cell development GO:0014032 59 26 0,000 0,04788857 0,06106043 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04788857 0,06102858 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04788857 0,06099676 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04788857 0,06096497 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04788857 0,06093322 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04788857 0,0609015 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04788857 0,06086981 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04788857 0,06083816 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,04788857 0,06080654 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04788857 0,06077495 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04788857 0,0607434 ! blastocyst development GO:0001824 50 26 0,000 0,04788857 0,06071187 ! telomere organization GO:0032200 46 26 0,000 0,04788857 0,06068038 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04788857 0,06064893 ! neural tube closure GO:0001843 58 26 0,000 0,04788857 0,0606175 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04788857 0,06058611 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04788857 0,06055475 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0496846 0,06279332 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0496846 0,06276085 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0496846 0,06272842 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0496846 0,06269602 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,0496846 0,06266365 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0496846 0,06263131 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0496846 0,06259901 ! iron ion transport GO:0006826 65 27 0,000 0,0496846 0,06256675 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0496846 0,06253451 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0496846 0,06250231 ! tube lumen formation GO:0035148 59 27 0,000 0,0496846 0,06247014 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,0496846 0,06243801 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,0496846 0,06240591 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,0496846 0,06237384 ! response to starvation GO:0042594 47 27 0,000 0,0496846 0,0623418 ! response to toxin GO:0009636 49 27 0,000 0,0496846 0,0623098 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,0496846 0,06227783 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,0496846 0,06224589 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,0496846 0,06221399 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0496846 0,06218211 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0496846 0,06215027 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,0514773 0,06435979 ! neuron fate commitment GO:0048663 52 28 0,000 0,0514773 0,06432687 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,0514773 0,06429399 ! protein amino acid acylation GO:0043543 59 28 0,000 0,0514773 0,06426113 ! vesicle docking GO:0048278 55 28 0,000 0,0514773 0,06422831 ! circadian rhythm GO:0007623 56 28 0,000 0,0514773 0,06419553 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,0514773 0,06416277 ! fat cell differentiation GO:0045444 57 28 0,000 0,0514773 0,06413006 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,0514773 0,06409737 ! sperm motility GO:0030317 37 28 0,000 0,0514773 0,06406472 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,0514773 0,0640321 ! base-excision repair GO:0006284 41 28 0,000 0,0514773 0,06399951 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,0514773 0,06396696 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,0514773 0,06393444 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,0514773 0,06390195 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,0514773 0,0638695 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,0514773 0,06383708 ! glutathione metabolic process GO:0006749 42 28 0,000 0,0514773 0,06380469 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,0514773 0,06377233 ! lipid oxidation GO:0034440 48 28 0,000 0,0514773 0,06374001 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,0514773 0,06370772 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05326666 0,06588884 ! translational initiation GO:0006413 66 29 0,000 0,05326666 0,06585549 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05326666 0,06582218 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05326666 0,0657889 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,05326666 0,06575566 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05326666 0,06572245 ! primary neural tube formation GO:0014020 61 29 0,000 0,05326666 0,06568927 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05326666 0,06565613 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05326666 0,06562302 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05326666 0,06558995 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05326666 0,0655569 ! somitogenesis GO:0001756 52 29 0,000 0,05326666 0,06552389 ! synaptogenesis GO:0007416 46 29 0,000 0,05326666 0,06549092 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05326666 0,06545797 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05326666 0,06542506 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05326666 0,06539219 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05326666 0,06535934 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0550527 0,06751694 ! phenol metabolic process GO:0018958 56 30 0,000 0,0550527 0,06748306 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0550527 0,06744922 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0550527 0,06741541 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0550527 0,06738163 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0550527 0,06734789 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0550527 0,06731419 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0550527 0,06728051 ! acute-phase response GO:0006953 50 30 0,000 0,0550527 0,06724687 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0550527 0,06721326 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0550527 0,06717969 ! myofibril assembly GO:0030239 50 30 0,000 0,0550527 0,06714615 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,0550527 0,06711265 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0550527 0,06707917 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0550527 0,06704573 ! cell fate determination GO:0001709 64 30 0,000 0,0550527 0,06701233 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0550527 0,06697896 ! phospholipid transport GO:0015914 65 30 0,000 0,0550527 0,06694562 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0550527 0,06691231 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0550527 0,06687904 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0550527 0,0668458 ! tissue homeostasis GO:0001894 50 30 0,000 0,0550527 0,06681259 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,0550527 0,06677942 ! regulation of coagulation GO:0050818 52 30 0,000 0,0550527 0,06674627 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,05683542 0,06887347 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,05683542 0,06883933 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,05683542 0,06880522 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,05683542 0,06877114 ! cell junction assembly GO:0034329 85 31 0,000 0,05683542 0,06873709 ! regulation of innate immune response GO:0045088 57 31 0,000 0,05683542 0,06870308 ! ovulation cycle process GO:0022602 55 31 0,000 0,05683542 0,0686691 ! peptide transport GO:0015833 60 31 0,000 0,05683542 0,06863516 ! male gonad development GO:0008584 56 31 0,000 0,05683542 0,06860125 ! detection of light stimulus GO:0009583 44 31 0,000 0,05683542 0,06856737 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,05683542 0,06853353 ! natural killer cell activation GO:0030101 50 31 0,000 0,05683542 0,06849972 ! cofactor catabolic process GO:0051187 54 31 0,000 0,05683542 0,06846594 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,05683542 0,0684322 ! eye morphogenesis GO:0048592 65 31 0,000 0,05683542 0,06839849 ! response to heat GO:0009408 54 31 0,000 0,05683542 0,06836481 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,05683542 0,06833116 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,05861482 0,07043582 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,05861482 0,07040119 ! collagen metabolic process GO:0032963 49 32 0,000 0,05861482 0,07036659 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,05861482 0,07033203 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,05861482 0,0702975 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,05861482 0,07026301 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,05861482 0,07022855 ! muscle cell development GO:0055001 52 32 0,000 0,05861482 0,07019412 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,05861482 0,07015973 ! ovulation cycle GO:0042698 57 32 0,000 0,05861482 0,07012537 ! hindbrain development GO:0030902 65 32 0,000 0,05861482 0,07009105 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,05861482 0,07005676 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,05861482 0,0700225 ! gene silencing GO:0016458 71 32 0,000 0,05861482 0,06998828 ! regulation of pH GO:0006885 56 33 0,000 0,06039092 0,07207378 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06039092 0,07203858 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,06039092 0,07200343 GO:0055092|sterol homeostasis, ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06039092 0,0719683 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06039092 0,07193321 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,06039092 0,07189816 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06039092 0,07186314 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06039092 0,07182815 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06039092 0,0717932 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06039092 0,07175828 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06039092 0,07172339 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06039092 0,07168854 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06216372 0,07375715 ! glial cell differentiation GO:0010001 67 34 0,000 0,06216372 0,07372134 ! post-embryonic development GO:0009791 76 34 0,000 0,06216372 0,07368557 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06216372 0,07364984 ! cholesterol transport GO:0030301 62 34 0,000 0,06216372 0,07361414 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06216372 0,07357847 ! spliceosome assembly GO:0000245 75 34 0,000 0,06216372 0,07354284 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06216372 0,07350724 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06216372 0,07347168 ! cell fate specification GO:0001708 56 34 0,000 0,06216372 0,07343615 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,06216372 0,07340066 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06216372 0,0733652 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06216372 0,07332978 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06393322 0,07538072 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06393322 0,07534436 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06393322 0,07530803 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06393322 0,07527174 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06393322 0,07523548 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06393322 0,07519926 ! membrane docking GO:0022406 69 35 0,000 0,06393322 0,07516307 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06393322 0,07512692 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06393322 0,0750908 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06393322 0,07505471 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06393322 0,07501866 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06393322 0,07498265 ! telencephalon development GO:0021537 81 35 0,000 0,06393322 0,07494667 ! sterol transport GO:0015918 63 35 0,000 0,06393322 0,07491072 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06393322 0,07487481 ! placenta development GO:0001890 53 35 0,000 0,06393322 0,07483894 ! vesicle localization GO:0051648 70 35 0,000 0,06393322 0,07480309 ! regulation of muscle development GO:0048634 82 36 0,000 0,06569943 0,0768328 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,06569943 0,07679604 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,06569943 0,07675931 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,06569943 0,07672262 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,06569943 0,07668596 ! protein targeting to membrane GO:0006612 75 36 0,000 0,06569943 0,07664934 ! regulation of proteolysis GO:0030162 77 36 0,000 0,06569943 0,07661275 ! aerobic respiration GO:0009060 56 36 0,000 0,06569943 0,0765762 ! cytokine production GO:0001816 68 36 0,000 0,06569943 0,07653968 ! embryonic organ development GO:0048568 67 36 0,000 0,06569943 0,0765032 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,06569943 0,07646675 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,06569943 0,07643034 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,06746237 0,07844386 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,06746237 0,07840655 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,06746237 0,07836926 ! sister chromatid segregation GO:0000819 65 37 0,000 0,06746237 0,07833201 ! actomyosin structure organization GO:0031032 68 37 0,000 0,06746237 0,0782948 ! cell junction organization GO:0034330 96 37 0,000 0,06746237 0,07825762 ! tissue remodeling GO:0048771 78 37 0,000 0,06746237 0,07822048 ! female gonad development GO:0008585 71 37 0,000 0,06746237 0,07818338 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,06746237 0,07814631 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,06746237 0,07810927 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,06922202 0,08010866 ! meiosis I GO:0007127 74 38 0,000 0,06922202 0,08007073 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,06922202 0,08003284 ! organic anion transport GO:0015711 82 38 0,000 0,06922202 0,07999498 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,06922202 0,07995716 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,06922202 0,07991937 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,06922202 0,07988162 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,06922202 0,07984391 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,06922202 0,07980623 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,06922202 0,07976858 ! spermatid development GO:0007286 69 38 0,000 0,06922202 0,07973097 ! glycogen metabolic process GO:0005977 63 38 0,000 0,06922202 0,0796934 ! neural tube formation GO:0001841 79 38 0,000 0,06922202 0,07965586 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,0709784 0,08163853 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,0709784 0,08160011 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,0709784 0,08156173 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,0709784 0,08152338 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,0709784 0,08148507 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,0709784 0,0814468 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,0709784 0,08140856 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,0709784 0,08137036 ! glucan metabolic process GO:0044042 64 39 0,000 0,0709784 0,08133219 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07273152 0,08330197 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07273152 0,08326293 ! learning GO:0007612 82 40 0,000 0,07273152 0,08322394 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07273152 0,08318497 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07273152 0,08314605 ! lipid homeostasis GO:0055088 75 40 0,000 0,07273152 0,08310716 ! mismatch repair GO:0006298 58 40 0,000 0,07273152 0,0830683 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,07273152 0,08302949 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07273152 0,08299071 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07448138 0,08494772 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07448138 0,08490808 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07448138 0,08486847 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,07448138 0,08482891 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,07448138 0,08478938 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07448138 0,08474989 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07448138 0,08471043 ! gliogenesis GO:0042063 91 41 0,000 0,07448138 0,08467101 ! feeding behavior GO:0007631 69 41 0,000 0,07448138 0,08463163 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07448138 0,08459229 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,07448138 0,08455298 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07448138 0,0845137 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,07448138 0,08447447 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07448138 0,08443527 ! RNA modification GO:0009451 64 41 0,000 0,07448138 0,08439611 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,07622798 0,08633517 ! ear morphogenesis GO:0042471 64 42 0,000 0,07622798 0,08629516 ! organic ether metabolic process GO:0018904 59 42 0,000 0,07622798 0,08625519 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,07622798 0,08621526 ! T cell differentiation GO:0030217 93 42 0,000 0,07622798 0,08617537 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,07622798 0,08613551 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,07622798 0,08609568 ! regulation of protein secretion GO:0050708 77 42 0,000 0,07622798 0,0860559 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,07622798 0,08601615 ! cytokinesis GO:0000910 84 42 0,000 0,07622798 0,08597644 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,07622798 0,08593676 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,07797134 0,08786162 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,07797134 0,08782111 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,07797134 0,08778064 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,07797134 0,08774021 ! regulation of tube size GO:0035150 76 43 0,000 0,07797134 0,08769981 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,07797134 0,08765945 ! glucose transport GO:0015758 66 43 0,000 0,07797134 0,08761913 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,07797134 0,08757885 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,07797134 0,0875386 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,07797134 0,08749839 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,07797134 0,08745821 ! segmentation GO:0035282 78 43 0,000 0,07797134 0,08741808 ! ion transmembrane transport GO:0034220 79 43 0,000 0,07797134 0,08737798 ! neuron migration GO:0001764 85 43 0,000 0,07797134 0,08733791 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,07797134 0,08729789 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,07971146 0,08920527 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,07971146 0,08916442 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,07971146 0,08912361 ! hexose transport GO:0008645 68 44 0,000 0,07971146 0,08908284 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,07971146 0,08904211 ! phagocytosis GO:0006909 105 44 0,000 0,07971146 0,08900142 ! double-strand break repair GO:0006302 85 44 0,000 0,07971146 0,08896076 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,08144834 0,09085767 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,08144834 0,0908162 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,08144834 0,09077477 ! B cell differentiation GO:0030183 124 45 0,000 0,08144834 0,09073338 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,08144834 0,09069202 ! female gamete generation GO:0007292 71 45 0,000 0,08144834 0,09065071 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,08144834 0,09060943 ! polyol metabolic process GO:0019751 77 45 0,000 0,08144834 0,09056818 ! developmental growth GO:0048589 88 45 0,000 0,08144834 0,09052698 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,083182 0,09241183 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,083182 0,09236983 ! glycolysis GO:0006096 71 46 0,000 0,083182 0,09232786 ! leukocyte migration GO:0050900 75 46 0,000 0,083182 0,09228593 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,083182 0,09224404 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,083182 0,09220219 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,083182 0,09216037 ! pigmentation GO:0043473 103 46 0,000 0,083182 0,09211859 ! cell growth GO:0016049 90 46 0,000 0,083182 0,09207685 ! neural tube development GO:0021915 91 47 0,000 0,08491243 0,09394975 ! positive regulation of defense response GO:0031349 88 48 0,000 0,08663964 0,0958174 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,08663964 0,09577404 ! mitochondrial transport GO:0006839 94 48 0,000 0,08663964 0,09573073 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,08663964 0,09568745 ! cellular component disassembly GO:0022411 89 48 0,000 0,08663964 0,09564421 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,08663964 0,09560101 ! male sex differentiation GO:0046661 93 48 0,000 0,08663964 0,09555785 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,08663964 0,09551473 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,08663964 0,09547165 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,08663964 0,0954286 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,08663964 0,0953856 ! methylation GO:0032259 97 48 0,000 0,08663964 0,09534263 ! response to calcium ion GO:0051592 94 49 0,000 0,08836364 0,09719603 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,08836364 0,09715228 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,08836364 0,09710858 ! JNK cascade GO:0007254 106 49 0,000 0,08836364 0,09706492 ! protein homooligomerization GO:0051260 84 49 0,000 0,08836364 0,09702129 ! regulation of ion transport GO:0043269 86 50 0,000 0,09008444 0,09886625 ! endocrine system development GO:0035270 109 50 0,000 0,09008444 0,09882186 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,09008444 0,0987775 ! activation of caspase activity GO:0006919 95 50 0,000 0,09008444 0,09873319 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09008444 0,09868891 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09008444 0,09864468 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09008444 0,09860048 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09008444 0,09855633 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,09180203 0,10039049 ! viral infectious cycle GO:0019058 104 51 0,000 0,09180203 0,10034558 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,09180203 0,1003007 ! peptide metabolic process GO:0006518 80 51 0,000 0,09180203 0,10025586 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09180203 0,10021106 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09180203 0,10016631 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,09351643 0,10199136 ! Notch signaling pathway GO:0007219 111 52 0,000 0,09351643 0,10194585 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,09351643 0,10190038 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,09351643 0,10185495 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,09351643 0,10180956 ! excretion GO:0007588 87 52 0,000 0,09351643 0,10176421 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,09351643 0,1017189 ! histone modification GO:0016570 104 52 0,000 0,09351643 0,10167363 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,09351643 0,1016284 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,09351643 0,10158321 ! amino acid activation GO:0043038 98 52 0,000 0,09351643 0,10153807 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,09522765 0,10335013 ! inner ear development GO:0048839 89 53 0,000 0,09522765 0,10330424 ! chromatin remodeling GO:0006338 122 53 0,000 0,09522765 0,10325839 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,09522765 0,10321257 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,09522765 0,1031668 ! vesicle organization GO:0016050 127 53 0,000 0,09522765 0,10312107 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,09522765 0,10307538 ! regulation of translational initiation GO:0006446 87 54 0,000 0,09693568 0,10487771 ! neuromuscular process GO:0050905 107 54 0,000 0,09693568 0,10483128 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,09693568 0,1047849 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,09693568 0,10473855 ! membrane fusion GO:0006944 122 54 0,000 0,09693568 0,10469225 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,09693568 0,10464598 ! covalent chromatin modification GO:0016569 115 54 0,000 0,09693568 0,10459976 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,09693568 0,10455358 ! regulation of cell shape GO:0008360 142 54 0,000 0,09693568 0,10450744 ! RNA catabolic process GO:0006401 103 55 0,000 0,09864053 0,10629855 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,09864053 0,10625169 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,09864053 0,10620486 ! cell recognition GO:0008037 98 55 0,000 0,09864053 0,10615807 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,09864053 0,10611133 ! cell maturation GO:0048469 107 55 0,000 0,09864053 0,10606462 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,09864053 0,10601796 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,09864053 0,10597134 ! glucose catabolic process GO:0006007 88 56 0,000 0,10034222 0,10775211 ! RNA elongation GO:0006354 90 56 0,000 0,10034222 0,10770476 ! chloride transport GO:0006821 102 57 0,000 0,10204074 0,10947981 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,10204074 0,10943175 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,10204074 0,10938373 ! regulation of actin filament length GO:0030832 118 58 0,000 0,1037361 0,11115232 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,1037361 0,11110359 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,1037361 0,1110549 ! aging GO:0007568 112 58 0,000 0,1037361 0,11100626 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,1037361 0,11095766 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,1037361 0,1109091 ! nuclear export GO:0051168 110 59 0,000 0,10542831 0,11266901 ! establishment of organelle localization GO:0051656 122 59 0,000 0,10542831 0,11261974 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,10711737 0,11437401 ! DNA catabolic process GO:0006308 94 60 0,000 0,10711737 0,11432404 ! regulation of endocytosis GO:0030100 104 60 0,000 0,10711737 0,11427412 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,10711737 0,11422424 ! adult behavior GO:0030534 104 60 0,000 0,10711737 0,1141744 ! positive regulation of secretion GO:0051047 110 61 0,000 0,10880329 0,11592081 ! regulation of cellular component size GO:0032535 125 61 0,000 0,10880329 0,11587028 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,10880329 0,11581979 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,10880329 0,11576935 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,10880329 0,11571895 ! regulation of heart contraction GO:0008016 123 61 0,000 0,10880329 0,11566859 ! camera-type eye development GO:0043010 126 61 0,000 0,10880329 0,11561828 ! proton transport GO:0015992 117 61 0,000 0,10880329 0,11556801 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,10880329 0,11551779 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11048607 0,11725346 ! tRNA processing GO:0008033 102 62 0,000 0,11048607 0,11720255 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,11048607 0,11715168 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,11216572 0,11888107 ! regulation of mitosis GO:0007088 112 63 0,000 0,11216572 0,11882951 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,11216572 0,118778 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,11216572 0,11872654 ! hydrogen transport GO:0006818 121 64 0,000 0,11384225 0,12044895 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,11384225 0,1203968 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,11384225 0,12034471 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,11551566 0,12206088 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,11551566 0,12200811 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,11551566 0,12195538 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,11551566 0,1219027 ! ear development GO:0043583 114 66 0,000 0,11718596 0,12361196 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,11718596 0,12355861 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,11718596 0,1235053 ! gonad development GO:0008406 115 66 0,000 0,11718596 0,12345204 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,11718596 0,12339883 ! chromosome segregation GO:0007059 127 67 0,000 0,11885314 0,12510049 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,11885314 0,12504661 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,11885314 0,12499278 ! secondary metabolic process GO:0019748 125 67 0,000 0,11885314 0,124939 ! hexose catabolic process GO:0019320 113 68 0,000 0,12051723 0,12663381 ! extracellular matrix organization GO:0030198 146 68 0,000 0,12051723 0,12657936 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,12051723 0,12652497 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,12051723 0,12647062 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,12051723 0,12641632 ! adaptive immune response GO:0002250 126 68 0,000 0,12051723 0,12636206 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,12051723 0,12630785 ! cell projection assembly GO:0030031 138 68 0,000 0,12051723 0,12625369 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,12217822 0,12793888 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,12217822 0,12788406 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,12217822 0,12782929 ! developmental maturation GO:0021700 128 69 0,000 0,12217822 0,12777457 ! single fertilization GO:0007338 83 69 0,000 0,12217822 0,1277199 ! cell redox homeostasis GO:0045454 114 70 0,000 0,12383613 0,12939763 ! germ cell development GO:0007281 133 70 0,000 0,12383613 0,12934231 ! activation of immune response GO:0002253 120 70 0,000 0,12383613 0,12928703 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,12383613 0,1292318 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,12549094 0,13090281 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,12549094 0,13084694 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,12549094 0,13079111 ! carbohydrate transport GO:0008643 114 72 0,000 0,12714268 0,13245611 ! B cell activation GO:0042113 179 72 0,000 0,12714268 0,13239965 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,12714268 0,13234323 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,12714268 0,13228687 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,12714268 0,13223055 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,12714268 0,13217428 ! humoral immune response GO:0006959 115 73 0,000 0,12879135 0,13383125 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,12879135 0,13377434 ! regulation of immune effector process GO:0002697 156 73 0,000 0,12879135 0,13371749 ! acute inflammatory response GO:0002526 118 74 0,000 0,13043694 0,1353685 ! amino acid transport GO:0006865 148 74 0,000 0,13043694 0,13531102 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,13043694 0,13525359 ! organelle localization GO:0051640 155 74 0,000 0,13043694 0,1351962 ! transition metal ion transport GO:0000041 143 75 0,000 0,13207948 0,13684061 ! reproductive structure development GO:0048608 131 75 0,000 0,13207948 0,1367826 ! eye development GO:0001654 155 75 0,000 0,13207948 0,13672465 ! rhythmic process GO:0048511 142 75 0,000 0,13207948 0,13666674 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,13371896 0,13830458 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,13371896 0,13824605 ! learning or memory GO:0007611 161 76 0,000 0,13371896 0,13818757 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,13371896 0,13812914 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,13371896 0,13807076 ! amine catabolic process GO:0009310 136 77 0,000 0,13535538 0,1397014 ! neurotransmitter transport GO:0006836 142 77 0,000 0,13535538 0,1396424 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,13535538 0,13958346 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,13535538 0,13952456 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,13535538 0,13946571 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,13535538 0,13940692 ! antigen processing and presentation GO:0019882 117 78 0,000 0,13698877 0,14102973 ! fertilization GO:0009566 99 78 0,000 0,13698877 0,14097033 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,13698877 0,14091097 ! blood coagulation GO:0007596 151 79 0,000 0,13861911 0,14252798 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,13861911 0,14246802 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,13861911 0,14240811 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,13861911 0,14234825 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,13861911 0,14228844 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,14024642 0,14389836 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,14024642 0,14383795 ! meiosis GO:0007126 143 81 0,000 0,1418707 0,14544277 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,1418707 0,14538176 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1418707 0,14532081 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,14349196 0,14691989 ! protein import into nucleus GO:0006606 174 82 0,000 0,14349196 0,14685834 ! meiotic cell cycle GO:0051321 144 82 0,000 0,14349196 0,14679684 ! exocytosis GO:0006887 153 83 0,000 0,1451102 0,14839021 ! response to drug GO:0042493 149 83 0,000 0,1451102 0,14832812 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,1451102 0,14826609 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,1451102 0,1482041 ! nuclear import GO:0051170 177 83 0,000 0,1451102 0,14814217 ! inorganic anion transport GO:0015698 156 83 0,000 0,1451102 0,14808029 ! response to metal ion GO:0010038 158 84 0,000 0,14672543 0,14966606 ! T cell activation GO:0042110 189 84 0,000 0,14672543 0,1496036 ! response to nutrient GO:0007584 135 84 0,000 0,14672543 0,14954118 ! digestion GO:0007586 130 84 0,000 0,14672543 0,14947882 ! regulation of ligase activity GO:0051340 147 84 0,000 0,14672543 0,14941651 ! hemostasis GO:0007599 165 85 0,000 0,14833765 0,15099537 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,14833765 0,15093248 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,14833765 0,15086964 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,14833765 0,15080686 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,14994687 0,15237945 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,1515531 0,1539477 ! alcohol catabolic process GO:0046164 142 87 0,000 0,1515531 0,15388371 ! nucleosome assembly GO:0006334 126 87 0,000 0,1515531 0,15381978 ! cellular respiration GO:0045333 143 88 0,000 0,15315633 0,15538244 ! amine biosynthetic process GO:0009309 146 88 0,000 0,15315633 0,15531794 ! sensory perception of smell GO:0007608 117 88 0,000 0,15315633 0,15525349 ! chromatin assembly GO:0031497 128 88 0,000 0,15315633 0,1551891 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,15315633 0,15512476 ! cellular defense response GO:0006968 123 89 0,000 0,15475658 0,15668062 ! protein localization in nucleus GO:0034504 192 89 0,000 0,15475658 0,15661572 ! regulation of neurological system process GO:0031644 175 89 0,000 0,15475658 0,15655086 ! response to inorganic substance GO:0010035 173 90 0,000 0,15635386 0,15810119 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,15635386 0,15803578 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,15635386 0,15797042 ! response to unfolded protein GO:0006986 139 90 0,000 0,15635386 0,15790512 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,15635386 0,15783987 ! defense response to bacterium GO:0042742 112 91 0,000 0,15794816 0,15938346 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,15953949 0,16092278 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,16112786 0,16245784 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,16112786 0,16239082 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,16112786 0,16232386 ! vitamin metabolic process GO:0006766 153 93 0,000 0,16112786 0,16225695 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,16271327 0,16378596 ! female pregnancy GO:0007565 166 94 0,000 0,16271327 0,1637185 ! sterol metabolic process GO:0016125 166 94 0,000 0,16271327 0,1636511 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,16271327 0,16358375 ! regulation of defense response GO:0031347 171 95 0,000 0,16429573 0,16510673 ! nucleosome organization GO:0034728 143 95 0,000 0,16429573 0,16503884 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,16429573 0,16497101 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,16429573 0,16490323 ! sex differentiation GO:0007548 171 96 0,000 0,16587524 0,16642021 ! response to protein stimulus GO:0051789 158 96 0,000 0,16587524 0,1663519 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,16745182 0,16786409 ! transcription initiation GO:0006352 171 97 0,000 0,16745182 0,16779524 ! leukocyte differentiation GO:0002521 232 98 0,000 0,16902545 0,16930266 ! forebrain development GO:0030900 210 98 0,000 0,16902545 0,16923327 ! mRNA transport GO:0051028 185 100 0,000 0,17216394 0,172305 ! positive regulation of immune response GO:0050778 175 100 0,000 0,17216394 0,17223444 ! hormone metabolic process GO:0042445 171 100 0,000 0,17216394 0,17216394