pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6329-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! embryonic organ development GO:0048568 57 36 5,000 6,807E-08 1,638E-04 ! embryonic organ morphogenesis GO:0048562 26 19 4,000 7,622E-08 9,169E-05 ! embryonic skeletal system development GO:0048706 85 51 5,000 5,846E-07 4,689E-04 ! skeletal system morphogenesis GO:0048705 105 59 5,000 1,406E-06 8,458E-04 ! immunoglobulin V(D)J recombination GO:0033152 21 5 2,000 2,047E-06 9,848E-04 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 2,000 2,047E-06 8,207E-04 ! peptidyl-serine phosphorylation GO:0018105 38 18 3,000 3,46E-06 1,189E-03 ! protein destabilization GO:0031648 9 6 2,000 4,075E-06 1,226E-03 ! peptidyl-serine modification GO:0018209 43 20 3,000 5,427E-06 1,451E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 5,000 5,809E-06 1,398E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 7,101E-06 1,553E-03 ! B cell lineage commitment GO:0002326 21 7 2,000 7,101E-06 1,424E-03 ! cranial nerve morphogenesis GO:0021602 11 7 2,000 7,101E-06 1,314E-03 ! T cell lineage commitment GO:0002360 16 7 2,000 7,101E-06 1,22E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 7,89E-06 1,266E-03 ! apoptotic nuclear changes GO:0030262 32 22 3,000 8,118E-06 1,221E-03 ! ER overload response GO:0006983 12 8 2,000 1,131E-05 1,601E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,131E-05 1,512E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,131E-05 1,432E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 1,384E-05 1,665E-03 ! somitogenesis GO:0001756 43 25 3,000 1,384E-05 1,586E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,403E-05 2,628E-03 ! V(D)J recombination GO:0033151 28 10 2,000 2,403E-05 2,513E-03 ! cellular iron ion homeostasis GO:0006879 51 29 3,000 2,551E-05 2,558E-03 ! germ cell migration GO:0008354 25 11 2,000 3,289E-05 3,166E-03 ! embryonic gut development GO:0048566 15 11 2,000 3,289E-05 3,044E-03 ! iron ion homeostasis GO:0055072 54 31 3,000 3,349E-05 2,984E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,366E-05 3,752E-03 ! cranial nerve development GO:0021545 20 12 2,000 4,366E-05 3,623E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,366E-05 3,502E-03 GO:0042130|negative regulation of T cell proliferation, ! lung development GO:0030324 144 67 4,000 5,026E-05 3,901E-03 ! embryonic skeletal system morphogenesis GO:0048704 59 35 3,000 5,47E-05 4,113E-03 ! respiratory tube development GO:0030323 150 70 4,000 6,209E-05 4,527E-03 ! regulation of protein stability GO:0031647 73 37 3,000 6,837E-05 4,838E-03 ! respiratory system development GO:0060541 153 72 4,000 7,109E-05 4,887E-03 ! non-recombinational repair GO:0000726 25 14 2,000 7,161E-05 4,786E-03 GO:0006303|double-strand break repair via nonhomologous end joining, ! T cell differentiation in the thymus GO:0033077 31 14 2,000 7,161E-05 4,657E-03 ! response to gamma radiation GO:0010332 28 14 2,000 7,161E-05 4,534E-03 ! nucleus organization GO:0006997 67 38 3,000 7,605E-05 4,692E-03 ! segmentation GO:0035282 67 39 3,000 8,436E-05 5,074E-03 ! T cell differentiation GO:0030217 81 41 3,000 1,029E-04 6,039E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 1,029E-04 5,895E-03 ! dorsal/ventral pattern formation GO:0009953 68 41 3,000 1,029E-04 5,758E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,092E-04 5,972E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,132E-04 6,053E-03 ! T cell activation GO:0042110 168 81 4,000 1,247E-04 6,522E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,32E-04 6,759E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,32E-04 6,618E-03 ! double-strand break repair GO:0006302 81 44 3,000 1,36E-04 6,68E-03 ! nerve development GO:0021675 28 18 2,000 1,578E-04 7,591E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,62E-04 7,644E-03 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 2,000 1,865E-04 8,63E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 1,914E-04 8,69E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,914E-04 8,529E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,185E-04 9,557E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,185E-04 9,386E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,185E-04 9,222E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,185E-04 9,063E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,424E-04 9,887E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,538E-04 0,01017625 ! gut development GO:0048565 39 21 2,000 2,538E-04 0,01000943 ! cartilage development GO:0051216 90 52 3,000 2,614E-04 0,0101456 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 2,637E-04 0,01007193 ! response to UV GO:0009411 104 53 3,000 2,815E-04 0,01058187 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,926E-04 0,0108292 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,926E-04 0,01066512 ! somatic diversification of immunoglobulins GO:0016445 50 22 2,000 2,926E-04 0,01050594 ! interphase GO:0051325 213 98 4,000 3,047E-04 0,0107815 ! cell cycle arrest GO:0007050 213 100 4,000 3,346E-04 0,01166746 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,472E-04 0,01193298 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 1,000 3,472E-04 0,01176491 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 3,472E-04 0,01160151 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 3,472E-04 0,01144258 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 3,472E-04 0,01128795 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,472E-04 0,01113745 ! microvillus organization GO:0032528 7 5 1,000 3,472E-04 0,0109909 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,472E-04 0,01084816 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,472E-04 0,01070908 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 1,000 3,472E-04 0,01057353 ! stem cell division GO:0017145 11 5 1,000 3,472E-04 0,01044136 GO:0048103|somatic stem cell division, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,728E-04 0,01107217 ! positive regulation of cell migration GO:0030335 126 57 3,000 3,728E-04 0,01093714 ! regulation of intracellular transport GO:0032386 101 57 3,000 3,728E-04 0,01080537 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 2,000 3,812E-04 0,01091753 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,812E-04 0,01078909 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,812E-04 0,01066364 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 4,312E-04 0,01192628 ! immunoglobulin production GO:0002377 55 25 2,000 4,312E-04 0,01179075 GO:0002440|production of molecular mediator of immune response, ! telomere organization GO:0032200 43 25 2,000 4,312E-04 0,01165827 GO:0000723|telomere maintenance, ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,538E-04 0,01213242 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,854E-04 0,01283311 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 4,854E-04 0,01269362 GO:0045936|negative regulation of phosphate metabolic process, ! somatic diversification of immune receptors GO:0002200 56 26 2,000 4,854E-04 0,01255713 ! forebrain regionalization GO:0021871 8 6 1,000 5,187E-04 0,01327724 ! male meiosis GO:0007140 7 6 1,000 5,187E-04 0,01313748 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 5,187E-04 0,01300063 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 5,187E-04 0,0128666 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 5,187E-04 0,01273531 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 5,187E-04 0,01260667 ! male sex determination GO:0030238 15 6 1,000 5,187E-04 0,0124806 ! deoxyribonucleoside metabolic process GO:0009120 8 6 1,000 5,187E-04 0,01235703 ! neural nucleus development GO:0048857 14 6 1,000 5,187E-04 0,01223588 ! nucleoside catabolic process GO:0009164 7 6 1,000 5,187E-04 0,01211709 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 1,000 5,187E-04 0,01200058 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 5,187E-04 0,01188629 GO:0007439|ectodermal gut development, ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,187E-04 0,01177415 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,437E-04 0,01222492 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,805E-04 0,01293266 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 6,063E-04 0,01338215 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,733E-04 0,01472616 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 6,907E-04 0,01497103 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 7,234E-04 0,01553974 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,234E-04 0,01540222 ! positive regulation of heart rate GO:0010460 10 7 1,000 7,234E-04 0,01526711 ! spinal cord patterning GO:0021511 13 7 1,000 7,234E-04 0,01513435 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 1,000 7,234E-04 0,01500388 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! phasic smooth muscle contraction GO:0014821 12 7 1,000 7,234E-04 0,01487565 ! purine salvage GO:0043101 10 7 1,000 7,234E-04 0,01474958 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,234E-04 0,01462564 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 7,234E-04 0,01450376 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 7,234E-04 0,01438389 ! negative regulation of kinase activity GO:0033673 131 68 3,000 7,305E-04 0,01440596 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 7,448E-04 0,01456935 ! regulation of B cell activation GO:0050864 50 30 2,000 7,448E-04 0,01445185 ! myeloid leukocyte activation GO:0002274 49 31 2,000 8,21E-04 0,0158032 ! response to ionizing radiation GO:0010212 65 32 2,000 9,02E-04 0,01722436 ! positive regulation of catabolic process GO:0009896 64 32 2,000 9,02E-04 0,01708874 ! regulation of caspase activity GO:0043281 122 72 3,000 9,059E-04 0,01702889 ! negative regulation of transferase activity GO:0051348 140 72 3,000 9,059E-04 0,01689688 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 1,000 9,607E-04 0,01778099 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,607E-04 0,01764526 ! macrophage chemotaxis GO:0048246 12 8 1,000 9,607E-04 0,01751159 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,607E-04 0,01737992 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 9,607E-04 0,01725022 ! macrophage activation GO:0042116 12 8 1,000 9,607E-04 0,01712244 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,607E-04 0,01699654 ! DNA topological change GO:0006265 12 8 1,000 9,607E-04 0,01687248 ! mast cell activation GO:0045576 14 8 1,000 9,607E-04 0,01675021 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 9,607E-04 0,01662971 ! cell fate specification GO:0001708 52 33 2,000 9,879E-04 0,01697796 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,004E-03 0,01713111 ! lymphocyte differentiation GO:0030098 167 75 3,000 1,056E-03 0,01788628 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,079E-03 0,01815108 ! regulation of catabolic process GO:0009894 161 76 3,000 1,109E-03 0,01853226 ! calcium-mediated signaling GO:0019722 62 35 2,000 1,175E-03 0,01949382 ! regulation of developmental growth GO:0048638 15 9 1,000 1,23E-03 0,0202764 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,23E-03 0,02013846 ! regulation of glycolysis GO:0006110 21 9 1,000 1,23E-03 0,02000239 ! microtubule bundle formation GO:0001578 21 9 1,000 1,23E-03 0,01986815 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,23E-03 0,01973569 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,23E-03 0,01960499 ! motor axon guidance GO:0008045 16 9 1,000 1,23E-03 0,01947601 ! protein heterooligomerization GO:0051291 16 9 1,000 1,23E-03 0,01934872 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,23E-03 0,01922308 ! induction of an organ GO:0001759 14 9 1,000 1,23E-03 0,01909906 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,23E-03 0,01897663 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,276E-03 0,01955522 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,281E-03 0,01950908 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,281E-03 0,01938638 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,383E-03 0,02079095 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,532E-03 0,02289435 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,532E-03 0,02275303 ! smoothened signaling pathway GO:0007224 16 10 1,000 1,532E-03 0,02261344 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,532E-03 0,02247555 ! pathogenesis GO:0009405 13 10 1,000 1,532E-03 0,02233934 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,532E-03 0,02220476 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 1,532E-03 0,0220718 ! DNA ligation GO:0006266 19 10 1,000 1,532E-03 0,02194042 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,532E-03 0,02181059 ! cellular metabolic compound salvage GO:0043094 14 10 1,000 1,532E-03 0,0216823 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,532E-03 0,0215555 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,532E-03 0,02143018 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,532E-03 0,0213063 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 17 10 1,000 1,532E-03 0,02118385 ! localization within membrane GO:0051668 20 10 1,000 1,532E-03 0,0210628 ! regulation of ligase activity GO:0051340 142 84 3,000 1,608E-03 0,02198009 ! mammary gland development GO:0030879 86 39 2,000 1,612E-03 0,02191387 ! ear morphogenesis GO:0042471 60 39 2,000 1,612E-03 0,02179076 ! regulation of protein transport GO:0051223 154 87 3,000 1,829E-03 0,02459031 GO:0070201|regulation of establishment of protein localization, ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,864E-03 0,02491728 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,865E-03 0,02479289 ! neuron fate specification GO:0048665 17 11 1,000 1,865E-03 0,02465667 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,865E-03 0,02452193 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,865E-03 0,02438866 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,865E-03 0,02425683 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,865E-03 0,02412641 ! ventral spinal cord development GO:0021517 21 11 1,000 1,865E-03 0,0239974 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,865E-03 0,02386975 ! UV protection GO:0009650 19 11 1,000 1,865E-03 0,02374346 ! vasoconstriction GO:0042310 18 11 1,000 1,865E-03 0,02361849 ! DNA methylation GO:0006306 19 11 1,000 1,865E-03 0,02349483 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,865E-03 0,02337246 ! developmental induction GO:0031128 19 11 1,000 1,865E-03 0,02325136 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 1,865E-03 0,02313151 ! regulation of DNA binding GO:0051101 155 88 3,000 1,908E-03 0,0235392 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,988E-03 0,02440886 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,139E-03 0,02612911 ! neural tube development GO:0021915 77 43 2,000 2,139E-03 0,02599715 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,139E-03 0,02586651 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 2,229E-03 0,02682002 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,229E-03 0,02668659 ! virus-host interaction GO:0019048 29 12 1,000 2,229E-03 0,02655448 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,229E-03 0,02642367 ! histone acetylation GO:0016573 26 12 1,000 2,229E-03 0,02629414 ! autonomic nervous system development GO:0048483 24 12 1,000 2,229E-03 0,02616588 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,229E-03 0,02603886 ! spleen development GO:0048536 22 12 1,000 2,229E-03 0,02591307 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,229E-03 0,02578848 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! B cell differentiation GO:0030183 107 44 2,000 2,286E-03 0,0263164 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,335E-03 0,02674714 ! regulation of T cell activation GO:0050863 158 94 3,000 2,427E-03 0,02767628 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,439E-03 0,02767666 ! response to insulin stimulus GO:0032868 95 46 2,000 2,598E-03 0,0293409 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,598E-03 0,02920379 ! leukocyte differentiation GO:0002521 202 96 3,000 2,62E-03 0,02931802 ! regulation of cell-cell adhesion GO:0022407 33 13 1,000 2,625E-03 0,02923405 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 1,000 2,625E-03 0,02909933 ! deoxyribonucleotide catabolic process GO:0009264 19 13 1,000 2,625E-03 0,02896585 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,625E-03 0,02883359 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,625E-03 0,02870252 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,625E-03 0,02857265 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,625E-03 0,02844394 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,72E-03 0,02934717 ! regulation of protein localization GO:0032880 176 97 3,000 2,72E-03 0,02921616 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,763E-03 0,02954135 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,934E-03 0,0312355 ! cellular component disassembly GO:0022411 86 48 2,000 2,934E-03 0,03109789 ! activation of caspase activity GO:0006919 84 48 2,000 2,934E-03 0,0309615 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,05E-03 0,03204482 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,05E-03 0,0319055 ! regulation of heart rate GO:0002027 24 14 1,000 3,05E-03 0,03176738 ! negative regulation of caspase activity GO:0043154 22 14 1,000 3,05E-03 0,03163045 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,05E-03 0,03149469 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,05E-03 0,0313601 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,296E-03 0,03374671 ! positive regulation of binding GO:0051099 78 51 2,000 3,487E-03 0,03554946 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 3,487E-03 0,03539946 ! regulation of the force of heart contraction GO:0002026 26 15 1,000 3,506E-03 0,03543797 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,991E-03 0,04017401 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,991E-03 0,04000662 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,991E-03 0,03984062 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,991E-03 0,03967599 GO:0031114|regulation of microtubule depolymerization, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,991E-03 0,03951271 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 3,991E-03 0,03935078 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,991E-03 0,03919016 ! neuron recognition GO:0008038 35 16 1,000 3,991E-03 0,03903085 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,317E-03 0,04205492 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 4,317E-03 0,04188534 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 1,000 4,505E-03 0,0435319 GO:0019692|deoxyribose phosphate metabolic process, ! negative regulation of peptidase activity GO:0010466 27 17 1,000 4,505E-03 0,04335777 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,505E-03 0,04318503 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 4,505E-03 0,04301366 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,505E-03 0,04284365 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,505E-03 0,04267497 ! neutrophil chemotaxis GO:0030593 27 17 1,000 4,505E-03 0,04250762 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,505E-03 0,04234158 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,505E-03 0,04217682 ! regulation of DNA replication GO:0006275 101 56 2,000 4,542E-03 0,04235705 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,049E-03 0,04689934 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 5,049E-03 0,04671896 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 5,049E-03 0,04653996 GO:0050886|endocrine process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,049E-03 0,04636233 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 5,258E-03 0,04810186 ! DNA catabolic process GO:0006308 86 59 2,000 5,258E-03 0,04791966 ! lipid phosphorylation GO:0046834 35 19 1,000 5,621E-03 0,05103089 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,621E-03 0,05083904 ! neuromuscular junction development GO:0007528 34 19 1,000 5,621E-03 0,05064863 ! peptide cross-linking GO:0018149 37 19 1,000 5,621E-03 0,05045965 ! prostaglandin metabolic process GO:0006693 37 19 1,000 5,621E-03 0,05027206 GO:0006692|prostanoid metabolic process, ! purine nucleotide catabolic process GO:0006195 29 19 1,000 5,621E-03 0,05008587 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,621E-03 0,04990105 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,771E-03 0,05104708 ! ear development GO:0043583 103 62 2,000 6,038E-03 0,05321568 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,221E-03 0,05462539 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,221E-03 0,05442675 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 6,221E-03 0,05422955 ! cellular response to starvation GO:0009267 33 20 1,000 6,221E-03 0,05403378 ! D-ribose metabolic process GO:0006014 29 20 1,000 6,221E-03 0,05383941 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 6,221E-03 0,05364644 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,849E-03 0,05885213 ! smooth muscle contraction GO:0006939 46 21 1,000 6,849E-03 0,05864269 ! regulation of vasoconstriction GO:0019229 39 21 1,000 6,849E-03 0,05843474 ! DNA modification GO:0006304 34 21 1,000 6,849E-03 0,05822826 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,849E-03 0,05802323 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,849E-03 0,05781964 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 6,849E-03 0,05761747 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 6,884E-03 0,05771027 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of cell growth GO:0030308 132 67 2,000 7,485E-03 0,06253041 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 7,505E-03 0,06247774 ! regulation of chemotaxis GO:0050920 40 22 1,000 7,505E-03 0,0622623 ! deoxyribonucleotide metabolic process GO:0009262 32 22 1,000 7,505E-03 0,06204834 ! central nervous system neuron development GO:0021954 46 22 1,000 7,505E-03 0,06183584 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,505E-03 0,0616248 ! ureteric bud development GO:0001657 43 22 1,000 7,505E-03 0,06141519 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,505E-03 0,06120701 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,505E-03 0,06100022 ! negative regulation of cell size GO:0045792 134 69 2,000 8,116E-03 0,06574772 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 8,116E-03 0,06552709 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,187E-03 0,06588272 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,187E-03 0,06566312 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,187E-03 0,06544497 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 8,187E-03 0,06522826 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 8,187E-03 0,06501299 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 47 23 1,000 8,187E-03 0,06479913 ! regulation of viral reproduction GO:0050792 38 23 1,000 8,187E-03 0,06458667 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 8,187E-03 0,0643756 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,187E-03 0,06416591 ! appendage morphogenesis GO:0035107 135 70 2,000 8,443E-03 0,06595335 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 8,777E-03 0,06834493 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 2,000 8,777E-03 0,06812446 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 8,897E-03 0,06883079 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,897E-03 0,06861018 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,897E-03 0,06839098 ! spinal cord development GO:0021510 47 24 1,000 8,897E-03 0,06817317 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 8,897E-03 0,06795675 ! regulation of behavior GO:0050795 43 24 1,000 8,897E-03 0,0677417 ! pentose metabolic process GO:0019321 35 24 1,000 8,897E-03 0,067528 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,897E-03 0,06731565 ! protein tetramerization GO:0051262 52 24 1,000 8,897E-03 0,06710463 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 9,12E-03 0,06856879 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 9,12E-03 0,06835518 ! axon guidance GO:0007411 139 73 2,000 9,47E-03 0,07075779 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 9,633E-03 0,0717572 ! myelination GO:0042552 45 25 1,000 9,633E-03 0,07153573 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 9,633E-03 0,07131562 ! chromosome condensation GO:0030261 45 25 1,000 9,633E-03 0,07109686 ! response to starvation GO:0042594 42 25 1,000 9,633E-03 0,07087944 ! interaction with host GO:0051701 62 25 1,000 9,633E-03 0,07066334 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 9,633E-03 0,07044856 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,633E-03 0,07023508 ! neural tube closure GO:0001843 49 25 1,000 9,633E-03 0,07002289 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 9,633E-03 0,06981197 ! regulation of transcription factor activity GO:0051090 126 74 2,000 9,827E-03 0,07100495 GO:0090046|regulation of transcription regulator activity, ! tube lumen formation GO:0035148 50 26 1,000 0,01039556 0,0748854 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01039556 0,07466186 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01039556 0,07443965 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01039556 0,07421876 ! response to estradiol stimulus GO:0032355 40 26 1,000 0,01039556 0,07399918 ! blastocyst development GO:0001824 49 26 1,000 0,01039556 0,07378089 ! positive regulation of ligase activity GO:0051351 124 77 2,000 0,01094731 0,07746829 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01094731 0,07724111 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01118371 0,07867841 ! neuron fate commitment GO:0048663 48 27 1,000 0,01118371 0,07844902 ! iron ion transport GO:0006826 59 27 1,000 0,01118371 0,07822097 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01118371 0,07799425 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01118371 0,07776883 ! primary neural tube formation GO:0014020 51 27 1,000 0,01118371 0,07754471 ! base-excision repair GO:0006284 41 27 1,000 0,01118371 0,07732188 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01118371 0,07710033 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01118371 0,07688004 ! dendrite development GO:0016358 59 28 1,000 0,01199736 0,08223834 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,01199736 0,08200471 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01199736 0,0817724 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01199736 0,08154141 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01199736 0,08131171 ! protein import into nucleus GO:0006606 158 80 2,000 0,01213808 0,0820343 ! response to hypoxia GO:0001666 171 81 2,000 0,01255086 0,08458648 ! nuclear import GO:0051170 161 81 2,000 0,01255086 0,0843502 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01255086 0,08411525 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01283619 0,08578851 ! tissue homeostasis GO:0001894 48 29 1,000 0,01283619 0,08555087 GO:0048871|multicellular organismal homeostasis, ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01297162 0,08621468 ! response to oxygen levels GO:0070482 176 83 2,000 0,01340037 0,08881895 ! determination of left/right symmetry GO:0007368 47 30 1,000 0,01369986 0,09055454 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01369986 0,09030645 GO:0008366|axon ensheathment, ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01369986 0,09005971 ! eye morphogenesis GO:0048592 60 30 1,000 0,01369986 0,08981431 ! response to heat GO:0009408 50 30 1,000 0,01369986 0,08957025 ! negative regulation of growth GO:0045926 155 84 2,000 0,01383713 0,09022256 ! response to unfolded protein GO:0006986 131 85 2,000 0,01428192 0,09287105 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01428192 0,09262073 GO:0002696|positive regulation of leukocyte activation, ! determination of bilateral symmetry GO:0009855 49 31 1,000 0,01458805 0,09435175 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01458805 0,09409879 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01458805 0,09384719 GO:0043433|negative regulation of transcription factor activity, ! tube morphogenesis GO:0035239 176 86 2,000 0,01473475 0,09453819 ! mitochondrion organization GO:0007005 148 86 2,000 0,01473475 0,09428676 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01519566 0,09697813 ! metanephros development GO:0001656 74 32 1,000 0,01550045 0,09866161 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01550045 0,09840129 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01550045 0,09814234 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01550045 0,09788474 ! hindbrain development GO:0030902 61 32 1,000 0,01550045 0,0976285 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01550045 0,0973736 ! gland development GO:0048732 206 88 2,000 0,01566464 0,09814877 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01643675 0,10271898 ! leukocyte chemotaxis GO:0030595 50 33 1,000 0,01643675 0,10245287 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01643675 0,10218814 ! response to protein stimulus GO:0051789 149 91 2,000 0,01712021 0,10616293 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01739662 0,10759964 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01739662 0,10732374 ! placenta development GO:0001890 53 34 1,000 0,01739662 0,10704926 ! phospholipid biosynthetic process GO:0008654 167 92 2,000 0,01762164 0,1081573 ! regulation of muscle development GO:0048634 70 35 1,000 0,01837976 0,11252339 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01837976 0,1122378 ! telencephalon development GO:0021537 68 35 1,000 0,01837976 0,11195365 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01837976 0,11167094 ! cytokine production GO:0001816 59 35 1,000 0,01837976 0,11138965 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01837976 0,11110978 ! neural tube formation GO:0001841 67 35 1,000 0,01837976 0,11083131 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01837976 0,11055423 ! odontogenesis GO:0042476 66 35 1,000 0,01837976 0,11027853 ! transcription initiation GO:0006352 153 94 2,000 0,01864892 0,11161521 ! forebrain development GO:0030900 188 95 2,000 0,0191748 0,11447781 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01938586 0,11545141 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01938586 0,11516635 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01938586 0,11488269 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02041461 0,12068197 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02041461 0,12038618 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02135992 0,12565274 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02146573 0,12596716 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02146573 0,12566067 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02146573 0,12535567 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02146573 0,12505214 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02146573 0,12475009 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,02146573 0,12444948 GO:0006073|cellular glucan metabolic process, ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02253889 0,13035716 ! negative regulation of binding GO:0051100 72 40 1,000 0,02363382 0,13636205 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,02363382 0,13603582 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02475022 0,14212176 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02588779 0,14830003 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02588779 0,14794777 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02588779 0,14759718 ! regulation of tube size GO:0035150 71 42 1,000 0,02588779 0,14724825 GO:0050880|regulation of blood vessel size, ! neuron migration GO:0001764 79 42 1,000 0,02588779 0,14690097 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,02704624 0,15311355 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02704624 0,15275413 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02704624 0,15239639 ! phagocytosis GO:0006909 90 43 1,000 0,02704624 0,15204032 ! biopolymer methylation GO:0043414 84 44 1,000 0,0282253 0,15829854 ! developmental growth GO:0048589 82 44 1,000 0,0282253 0,1579304 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02936821 0,16394409 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02936821 0,16356459 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02936821 0,16318684 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02936821 0,16281083 ! neuron fate determination GO:0048664 7 5 0,000 0,02936821 0,16243656 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02936821 0,162064 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02936821 0,16169314 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02936821 0,16132398 ! polyol transport GO:0015791 12 5 0,000 0,02936821 0,1609565 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02936821 0,16059069 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02936821 0,16022654 ! response to superoxide GO:0000303 10 5 0,000 0,02936821 0,15986403 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02936821 0,15950317 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02936821 0,15914392 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02936821 0,1587863 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02936821 0,15843027 ! female meiosis GO:0007143 7 5 0,000 0,02936821 0,15807584 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02936821 0,157723 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02936821 0,15737172 ! cobalt ion transport GO:0006824 11 5 0,000 0,02936821 0,157022 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02936821 0,15667384 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02936821 0,15632722 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02936821 0,15598212 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02936821 0,15563855 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02936821 0,15529649 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02936821 0,15495593 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02936821 0,15461685 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02936821 0,15427926 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02936821 0,15394314 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02936821 0,15360848 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02936821 0,15327528 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02936821 0,15294351 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02936821 0,15261318 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02936821 0,15228427 ! negative chemotaxis GO:0050919 14 5 0,000 0,02936821 0,15195678 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02936821 0,15163069 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02936821 0,151306 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02936821 0,1509827 ! behavioral response to pain GO:0048266 9 5 0,000 0,02936821 0,15066077 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02936821 0,15034022 ! Notch receptor processing GO:0007220 8 5 0,000 0,02936821 0,15002102 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02936821 0,14970318 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02936821 0,14938669 ! micturition GO:0060073 9 5 0,000 0,02936821 0,14907152 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02936821 0,14875769 ! copulation GO:0007620 9 5 0,000 0,02936821 0,14844517 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02936821 0,14813397 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02936821 0,14782406 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02936821 0,14751545 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02936821 0,14720813 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02936821 0,14690208 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02936821 0,14659731 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02936821 0,14629379 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02936821 0,14599153 ! grooming behavior GO:0007625 6 5 0,000 0,02936821 0,14569052 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02936821 0,14539075 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02936821 0,1450922 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02936821 0,14479488 ! response to protozoan GO:0001562 10 5 0,000 0,02936821 0,14449878 ! lymph vessel development GO:0001945 10 5 0,000 0,02936821 0,14420388 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02936821 0,14391019 ! endochondral ossification GO:0001958 16 5 0,000 0,02936821 0,14361769 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02936821 0,14332637 ! parathyroid gland development GO:0060017 13 5 0,000 0,02936821 0,14303624 ! anagen GO:0042640 6 5 0,000 0,02936821 0,14274728 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02936821 0,14245948 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02936821 0,14217284 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02936821 0,14188735 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02936821 0,14160301 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02936821 0,1413198 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02936821 0,14103773 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02936821 0,14075678 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02936821 0,14047694 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02936821 0,14019822 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02936821 0,1399206 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02936821 0,13964408 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02936821 0,13936864 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02936821 0,1390943 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02936821 0,13882103 ! histidine catabolic process GO:0006548 6 5 0,000 0,02936821 0,13854883 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02936821 0,1382777 ! valine metabolic process GO:0006573 10 5 0,000 0,02936821 0,13800762 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02936821 0,1377386 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02936821 0,13747063 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02936821 0,13720369 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02936821 0,1369378 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02936821 0,13667293 ! polyol catabolic process GO:0046174 7 5 0,000 0,02936821 0,13640908 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02936821 0,13614625 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02936821 0,13588443 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02936821 0,13562361 ! muscle cell migration GO:0014812 8 5 0,000 0,02936821 0,1353638 ! mitochondrial fission GO:0000266 8 5 0,000 0,02936821 0,13510498 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02936821 0,13484714 ! mRNA transcription GO:0009299 9 5 0,000 0,02936821 0,13459029 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02936821 0,13433441 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02936821 0,13407951 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02936821 0,13382557 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02936821 0,13357259 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02936821 0,13332057 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02936821 0,1330695 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02936821 0,13281937 ! response to food GO:0032094 6 5 0,000 0,02936821 0,13257017 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02936821 0,13232191 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02936821 0,13207458 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02936821 0,13182818 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02936821 0,13158269 ! forebrain neuron development GO:0021884 13 5 0,000 0,02936821 0,13133811 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02936821 0,13109444 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02936821 0,13085167 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02936821 0,1306098 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02936821 0,13036882 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02936821 0,13012873 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02936821 0,12988953 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02936821 0,1296512 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02936821 0,12941374 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02936821 0,12917715 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02936821 0,12894143 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02936821 0,12870656 ! basic amino acid transport GO:0015802 11 5 0,000 0,02936821 0,12847255 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02936821 0,12823939 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02936821 0,12800707 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02936821 0,12777559 ! depyrimidination GO:0045008 10 5 0,000 0,02936821 0,12754495 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02936821 0,12731514 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02936821 0,12708616 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02936821 0,12685799 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02936821 0,12663065 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02936821 0,12640412 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02936821 0,1261784 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02936821 0,12595348 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02936821 0,12572936 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02936821 0,12550604 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02936821 0,12528351 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02936821 0,12506177 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02936821 0,12484082 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02936821 0,12462064 ! response to arsenic GO:0046685 10 5 0,000 0,02936821 0,12440124 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02936821 0,1241826 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02936821 0,12396474 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02936821 0,12374764 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02936821 0,1235313 ! response to cadmium ion GO:0046686 7 5 0,000 0,02936821 0,12331571 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02936821 0,12310087 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02936821 0,12288679 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02936821 0,12267344 ! decidualization GO:0046697 11 5 0,000 0,02936821 0,12246084 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02936821 0,12224897 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02936821 0,12203783 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02936821 0,12182742 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02936821 0,12161773 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02936821 0,12140877 ! neural tube patterning GO:0021532 7 5 0,000 0,02936821 0,12120052 ! embryonic cleavage GO:0040016 6 5 0,000 0,02936821 0,12099298 ! peroxisome fission GO:0016559 5 5 0,000 0,02936821 0,12078616 ! histone demethylation GO:0016577 10 5 0,000 0,02936821 0,12058004 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02936821 0,12037462 ! mitotic recombination GO:0006312 9 5 0,000 0,02936821 0,1201699 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02936821 0,11996588 ! metaphase plate congression GO:0051310 7 5 0,000 0,02936821 0,11976255 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02936821 0,1195599 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02936821 0,11935794 ! enteric nervous system development GO:0048484 8 5 0,000 0,02936821 0,11915666 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02936821 0,11895606 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02936821 0,11875614 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02936821 0,11855688 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02936821 0,1183583 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02936821 0,11816037 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02936821 0,11796311 ! plasminogen activation GO:0031639 5 5 0,000 0,02936821 0,1177665 ! B cell homeostasis GO:0001782 13 5 0,000 0,02936821 0,11757055 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02936821 0,11737525 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02936821 0,1171806 ! metaphase GO:0051323 8 5 0,000 0,02936821 0,11698659 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02936821 0,11679323 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02936821 0,1166005 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02936821 0,11640841 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02936821 0,11621694 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02936821 0,11602611 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02936821 0,11583591 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02936821 0,11564632 ! response to redox state GO:0051775 5 5 0,000 0,02936821 0,11545736 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02936821 0,11526901 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02936821 0,11508127 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02936821 0,11489415 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02936821 0,11470763 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02936821 0,11452172 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02936821 0,11433641 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02936821 0,1141517 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02936821 0,11396758 ! striatum development GO:0021756 9 5 0,000 0,02936821 0,11378406 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02936821 0,11360113 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02936821 0,11341878 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02936821 0,11323702 ! glial cell migration GO:0008347 11 5 0,000 0,02936821 0,11305584 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02936821 0,11287524 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02936821 0,11269522 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02936821 0,11251577 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02936821 0,11233689 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02936821 0,11215857 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02936821 0,11198083 ! neuroprotection GO:0043526 6 5 0,000 0,02936821 0,11180364 ! neural plate development GO:0001840 8 5 0,000 0,02936821 0,11162702 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02936821 0,11145095 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02936821 0,11127544 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02936821 0,11110048 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02936821 0,11092606 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02936821 0,1107522 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02936821 0,11057888 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02936821 0,1104061 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02936821 0,11023386 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02936821 0,11006215 ! spindle assembly GO:0051225 6 5 0,000 0,02936821 0,10989098 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02936821 0,10972035 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02936821 0,10955024 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02936821 0,10938065 ! drug metabolic process GO:0017144 6 5 0,000 0,02936821 0,1092116 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02936821 0,10904306 ! organ regeneration GO:0031100 7 5 0,000 0,02936821 0,10887504 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02936821 0,10870754 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02936821 0,10854056 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02936821 0,10837408 ! leukocyte migration GO:0050900 68 45 1,000 0,02942468 0,1084162 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02942468 0,10825042 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02942468 0,10808516 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,02942468 0,10792039 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,02942468 0,10775613 ! cell growth GO:0016049 84 45 1,000 0,02942468 0,10759237 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,0306441 0,11188117 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,0306441 0,11171166 ! pigmentation GO:0043473 100 46 1,000 0,0306441 0,11154265 ! positive regulation of defense response GO:0031349 76 47 1,000 0,03188327 0,11587788 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03188327 0,1157031 ! methylation GO:0032259 90 47 1,000 0,03188327 0,11552885 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03314194 0,11990902 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,03314194 0,11972898 ! regulation of action potential GO:0001508 95 49 1,000 0,03441981 0,12415903 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03441981 0,12397316 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,03441981 0,12378785 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03441981 0,12360309 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,03441981 0,12341889 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03441981 0,12323523 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0351381 0,12562002 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0351381 0,12543364 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0351381 0,12524781 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0351381 0,12506253 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0351381 0,1248778 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0351381 0,12469361 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0351381 0,12450997 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0351381 0,12432687 ! sleep GO:0030431 13 6 0,000 0,0351381 0,1241443 ! response to oxygen radical GO:0000305 11 6 0,000 0,0351381 0,12396227 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0351381 0,12378078 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0351381 0,12359981 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0351381 0,12341937 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0351381 0,12323946 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0351381 0,12306007 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0351381 0,12288121 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0351381 0,12270286 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0351381 0,12252503 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0351381 0,12234771 ! response to zinc ion GO:0010043 9 6 0,000 0,0351381 0,12217091 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0351381 0,12199462 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0351381 0,12181883 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0351381 0,12164355 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0351381 0,12146878 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0351381 0,12129451 ! malate metabolic process GO:0006108 11 6 0,000 0,0351381 0,12112073 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0351381 0,12094745 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0351381 0,12077467 ! protein refolding GO:0042026 15 6 0,000 0,0351381 0,12060238 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0351381 0,12043058 ! opsonization GO:0008228 8 6 0,000 0,0351381 0,12025928 ! mating behavior GO:0007617 7 6 0,000 0,0351381 0,12008845 ! neuron remodeling GO:0016322 15 6 0,000 0,0351381 0,11991811 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0351381 0,11974826 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0351381 0,11957888 ! equilibrioception GO:0050957 14 6 0,000 0,0351381 0,11940999 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0351381 0,11924157 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0351381 0,11907362 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0351381 0,11890615 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0351381 0,11873914 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0351381 0,11857261 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0351381 0,11840654 ! toxin metabolic process GO:0009404 11 6 0,000 0,0351381 0,11824094 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0351381 0,1180758 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0351381 0,11791112 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0351381 0,1177469 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0351381 0,11758313 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0351381 0,11741982 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0351381 0,11725696 ! thymic T cell selection GO:0045061 12 6 0,000 0,0351381 0,11709456 ! protein lipoylation GO:0009249 10 6 0,000 0,0351381 0,1169326 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0351381 0,11677109 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0351381 0,11661003 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0351381 0,11644941 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0351381 0,11628923 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0351381 0,11612949 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0351381 0,11597019 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0351381 0,11581133 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0351381 0,1156529 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0351381 0,11549491 ! hyperosmotic response GO:0006972 9 6 0,000 0,0351381 0,11533734 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0351381 0,11518021 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0351381 0,1150235 ! urea metabolic process GO:0019627 7 6 0,000 0,0351381 0,11486722 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0351381 0,11471136 ! neutrophil activation GO:0042119 8 6 0,000 0,0351381 0,11455592 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0351381 0,11440091 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0351381 0,11424631 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0351381 0,11409213 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0351381 0,11393837 ! neuron apoptosis GO:0051402 9 6 0,000 0,0351381 0,11378502 ! nucleoside salvage GO:0043174 9 6 0,000 0,0351381 0,11363208 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0351381 0,11347956 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0351381 0,11332744 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0351381 0,11317573 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0351381 0,11302443 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0351381 0,11287353 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0351381 0,11272303 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0351381 0,11257293 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0351381 0,11242323 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0351381 0,11227393 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0351381 0,11212503 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0351381 0,11197652 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0351381 0,1118284 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0351381 0,11168067 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0351381 0,11153334 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0351381 0,11138639 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0351381 0,11123983 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0351381 0,11109365 ! response to UV-C GO:0010225 11 6 0,000 0,0351381 0,11094786 ! astrocyte development GO:0014002 15 6 0,000 0,0351381 0,11080245 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0351381 0,11065742 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0351381 0,11051277 ! interaction with symbiont GO:0051702 13 6 0,000 0,0351381 0,1103685 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0351381 0,1102246 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0351381 0,11008108 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0351381 0,10993793 ! response to copper ion GO:0046688 10 6 0,000 0,0351381 0,10979516 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0351381 0,10965275 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0351381 0,10951071 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0351381 0,10936904 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0351381 0,10922774 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0351381 0,1090868 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0351381 0,10894623 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0351381 0,10880601 ! hair follicle maturation GO:0048820 7 6 0,000 0,0351381 0,10866616 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0351381 0,10852666 ! Schwann cell development GO:0014044 15 6 0,000 0,0351381 0,10838753 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0351381 0,10824875 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0351381 0,10811032 ! subpallium development GO:0021544 10 6 0,000 0,0351381 0,10797225 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0351381 0,10783453 ! histone ubiquitination GO:0016574 8 6 0,000 0,0351381 0,10769716 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0351381 0,10756014 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0351381 0,10742347 ! G2 phase GO:0051319 16 6 0,000 0,0351381 0,10728715 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0351381 0,10715117 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0351381 0,10701553 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0351381 0,10688024 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0351381 0,10674529 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0351381 0,10661068 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0351381 0,10647641 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0351381 0,10634248 ! receptor internalization GO:0031623 10 6 0,000 0,0351381 0,10620888 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0351381 0,10607562 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0351381 0,1059427 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0351381 0,1058101 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0351381 0,10567784 ! protein deubiquitination GO:0016579 14 6 0,000 0,0351381 0,10554591 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0351381 0,1054143 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0351381 0,10528303 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0351381 0,10515208 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0351381 0,10502145 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0351381 0,10489115 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0351381 0,10476118 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0351381 0,10463152 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0351381 0,10450219 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0351381 0,10437317 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0351381 0,10424448 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0351381 0,1041161 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0351381 0,10398803 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0351381 0,10386028 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0351381 0,10373285 ! catecholamine transport GO:0051937 9 6 0,000 0,0351381 0,10360572 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0351381 0,10347891 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0351381 0,10335241 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0351381 0,10322622 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0351381 0,10310033 ! maternal placenta development GO:0001893 12 6 0,000 0,0351381 0,10297475 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0351381 0,10284948 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0351381 0,10272451 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0351381 0,10259984 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0351381 0,10247548 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0351381 0,10235142 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0351381 0,10222765 ! inner ear development GO:0048839 79 50 1,000 0,03571663 0,10378529 ! histone modification GO:0016570 91 50 1,000 0,03571663 0,1036601 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03571663 0,10353521 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03703213 0,10721938 ! cellular amino acid biosynthetic process GO:0008652 75 51 1,000 0,03703213 0,10709051 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03703213 0,10696195 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03836604 0,11068188 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,03836604 0,11054932 ! positive regulation of growth GO:0045927 90 52 1,000 0,03836604 0,11041709 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03836604 0,11028517 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03836604 0,11015356 ! amino acid activation GO:0043038 92 52 1,000 0,03836604 0,11002227 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,03836604 0,10989129 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03971809 0,11362869 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03971809 0,11349374 ! tRNA transcription GO:0009304 14 7 0,000 0,04087389 0,11665786 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04087389 0,11651964 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04087389 0,11638174 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04087389 0,11624418 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04087389 0,11610694 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04087389 0,11597002 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04087389 0,11583342 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04087389 0,11569715 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04087389 0,11556119 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04087389 0,11542556 ! prostate gland development GO:0030850 13 7 0,000 0,04087389 0,11529024 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04087389 0,11515524 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04087389 0,11502055 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04087389 0,11488618 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04087389 0,11475213 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04087389 0,11461838 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04087389 0,11448495 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04087389 0,11435183 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04087389 0,11421902 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04087389 0,11408651 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04087389 0,11395432 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04087389 0,11382242 ! glycolipid transport GO:0046836 10 7 0,000 0,04087389 0,11369084 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04087389 0,11355955 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04087389 0,11342857 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04087389 0,1132979 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04087389 0,11316752 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04087389 0,11303744 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04087389 0,11290766 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04087389 0,11277818 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04087389 0,112649 ! mRNA stabilization GO:0048255 18 7 0,000 0,04087389 0,11252011 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04087389 0,11239151 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04087389 0,11226321 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04087389 0,1121352 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04087389 0,11200749 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04087389 0,11188006 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04087389 0,11175292 ! lipoprotein transport GO:0042953 14 7 0,000 0,04087389 0,11162608 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04087389 0,11149952 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04087389 0,11137324 ! rhythmic behavior GO:0007622 15 7 0,000 0,04087389 0,11124726 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04087389 0,11112155 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04087389 0,11099613 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04087389 0,110871 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04087389 0,11074614 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04087389 0,11062157 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04087389 0,11049727 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04087389 0,11037326 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04087389 0,11024952 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04087389 0,11012606 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04087389 0,11000288 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04087389 0,10987997 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04087389 0,10975734 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04087389 0,10963498 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04087389 0,10951289 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04087389 0,10939107 ! adrenal gland development GO:0030325 17 7 0,000 0,04087389 0,10926953 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04087389 0,10914825 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04087389 0,10902724 ! ovulation GO:0030728 9 7 0,000 0,04087389 0,1089065 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04087389 0,10878603 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04087389 0,10866583 ! microtubule nucleation GO:0007020 20 7 0,000 0,04087389 0,10854589 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04087389 0,10842621 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04087389 0,1083068 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04087389 0,10818765 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04087389 0,10806876 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04087389 0,10795014 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04087389 0,10783177 ! galactose metabolic process GO:0006012 13 7 0,000 0,04087389 0,10771366 ! vesicle fusion GO:0006906 17 7 0,000 0,04087389 0,10759581 ! response to dietary excess GO:0002021 8 7 0,000 0,04087389 0,10747822 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04087389 0,10736089 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04087389 0,10724381 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04087389 0,10712699 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04087389 0,10701042 ! organ growth GO:0035265 15 7 0,000 0,04087389 0,1068941 ! nucleoside transport GO:0015858 8 7 0,000 0,04087389 0,10677804 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04087389 0,10666223 ! parturition GO:0007567 14 7 0,000 0,04087389 0,10654667 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04087389 0,10643136 ! rRNA modification GO:0000154 14 7 0,000 0,04087389 0,1063163 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04087389 0,10620148 ! spindle checkpoint GO:0031577 15 7 0,000 0,04087389 0,10608692 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04087389 0,1059726 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04087389 0,10585853 ! macrophage differentiation GO:0030225 11 7 0,000 0,04087389 0,1057447 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04087389 0,10563112 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04087389 0,10551778 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04087389 0,10540469 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04087389 0,10529184 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04087389 0,10517922 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04087389 0,10506685 ! fibrinolysis GO:0042730 10 7 0,000 0,04087389 0,10495472 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04087389 0,10484283 ! eating behavior GO:0042755 7 7 0,000 0,04087389 0,10473118 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04087389 0,10461976 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04087389 0,10450858 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04087389 0,10439764 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04087389 0,10428693 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04087389 0,10417646 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04087389 0,10406622 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04087389 0,10395621 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04087389 0,10384644 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04087389 0,10373689 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04087389 0,10362758 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04087389 0,1035185 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04087389 0,10340965 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04087389 0,10330102 ! regulation of meiosis GO:0040020 12 7 0,000 0,04087389 0,10319263 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04087389 0,10308446 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04087389 0,10297652 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04087389 0,1028688 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04087389 0,10276131 ! transcription termination GO:0006353 13 7 0,000 0,04087389 0,10265404 ! response to tumor cell GO:0002347 13 7 0,000 0,04087389 0,102547 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04087389 0,10244018 ! anaphase GO:0051322 17 7 0,000 0,04087389 0,10233358 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04087389 0,10222721 ! axonal fasciculation GO:0007413 18 7 0,000 0,04087389 0,10212105 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04087389 0,10201512 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04087389 0,1019094 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04087389 0,10180391 ! diuresis GO:0030146 12 7 0,000 0,04087389 0,10169863 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04087389 0,10159357 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04087389 0,10148872 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04087389 0,1013841 ! antibiotic transport GO:0042891 9 7 0,000 0,04087389 0,10127968 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04087389 0,10117549 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04087389 0,1010715 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04087389 0,10096774 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04087389 0,10086418 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04087389 0,10076083 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04087389 0,1006577 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04087389 0,10055478 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04087389 0,10045207 ! lymph node development GO:0048535 10 7 0,000 0,04087389 0,10034957 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04087389 0,10024727 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04087389 0,10014519 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04087389 0,10004331 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04087389 0,09994164 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04087389 0,09984018 ! adult feeding behavior GO:0008343 9 7 0,000 0,04087389 0,09973892 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04087389 0,09963787 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04087389 0,09953702 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04087389 0,09943637 ! muscle adaptation GO:0043500 14 7 0,000 0,04087389 0,09933593 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04087389 0,0992357 ! retina homeostasis GO:0001895 12 7 0,000 0,04087389 0,09913566 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04087389 0,09903582 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04087389 0,09893619 ! protein prenylation GO:0018342 18 7 0,000 0,04087389 0,09883676 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04087389 0,09873752 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04087389 0,09863849 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04087389 0,09853965 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04108803 0,09895677 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04108803 0,09885781 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,04108803 0,09875905 ! cell recognition GO:0008037 85 54 1,000 0,04108803 0,09866049 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,04108803 0,09856213 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,04247561 0,10178916 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04247561 0,10168787 ! aging GO:0007568 103 55 1,000 0,04247561 0,10158679 ! heart morphogenesis GO:0003007 97 55 1,000 0,04247561 0,10148591 ! RNA elongation GO:0006354 79 55 1,000 0,04247561 0,10138523 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04388056 0,1046349 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04388056 0,1045313 ! muscle fiber development GO:0048747 112 57 1,000 0,04530262 0,10781218 ! lipid modification GO:0030258 97 57 1,000 0,04530262 0,10770565 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04530262 0,10759932 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04657577 0,1105141 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04657577 0,11040522 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04657577 0,11029655 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04657577 0,1101881 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04657577 0,11007986 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04657577 0,10997183 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04657577 0,10986401 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04657577 0,10975641 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04657577 0,10964902 ! meiotic prophase I GO:0007128 13 8 0,000 0,04657577 0,10954183 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04657577 0,10943486 ! oligopeptide transport GO:0006857 15 8 0,000 0,04657577 0,10932809 ! UTP metabolic process GO:0046051 8 8 0,000 0,04657577 0,10922153 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04657577 0,10911518 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04657577 0,10900904 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04657577 0,1089031 ! succinate metabolic process GO:0006105 14 8 0,000 0,04657577 0,10879737 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04657577 0,10869185 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04657577 0,10858653 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04657577 0,10848141 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04657577 0,10837649 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04657577 0,10827178 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04657577 0,10816727 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04657577 0,10806296 ! reflex GO:0060004 16 8 0,000 0,04657577 0,10795886 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04657577 0,10785495 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04657577 0,10775124 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04657577 0,10764774 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04657577 0,10754443 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04657577 0,10744132 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04657577 0,1073384 ! pigment granule organization GO:0048753 16 8 0,000 0,04657577 0,10723569 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04657577 0,10713317 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04657577 0,10703084 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04657577 0,10692872 ! histidine metabolic process GO:0006547 16 8 0,000 0,04657577 0,10682678 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04657577 0,10672504 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04657577 0,1066235 ! glycine catabolic process GO:0006546 13 8 0,000 0,04657577 0,10652214 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04657577 0,10642098 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04657577 0,10632001 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04657577 0,10621924 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04657577 0,10611865 ! melanin metabolic process GO:0006582 15 8 0,000 0,04657577 0,10601825 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04657577 0,10591805 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04657577 0,10581803 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04657577 0,1057182 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04657577 0,10561856 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04657577 0,10551911 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04657577 0,10541984 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04657577 0,10532077 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04657577 0,10522187 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04657577 0,10512317 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04657577 0,10502464 ! osteoblast development GO:0002076 16 8 0,000 0,04657577 0,10492631 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04657577 0,10482815 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04657577 0,10473018 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04657577 0,10463239 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04657577 0,10453479 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04657577 0,10443737 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04657577 0,10434013 ! response to UV-B GO:0010224 16 8 0,000 0,04657577 0,10424306 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04657577 0,10414618 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04657577 0,10404948 ! intermediate filament organization GO:0045109 12 8 0,000 0,04657577 0,10395296 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04657577 0,10385662 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04657577 0,10376046 ! cellular extravasation GO:0045123 12 8 0,000 0,04657577 0,10366447 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04657577 0,10356866 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04657577 0,10347303 ! response to antibiotic GO:0046677 11 8 0,000 0,04657577 0,10337758 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04657577 0,1032823 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04657577 0,1031872 ! response to tropane GO:0014073 15 8 0,000 0,04657577 0,10309227 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04657577 0,10299751 ! melanosome transport GO:0032402 13 8 0,000 0,04657577 0,10290293 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04657577 0,10280853 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04657577 0,10271429 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04657577 0,10262023 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04657577 0,10252634 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04657577 0,10243263 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04657577 0,10233908 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04657577 0,10224571 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04657577 0,1021525 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04657577 0,10205947 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04657577 0,1019666 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04657577 0,1018739 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04657577 0,10178138 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04657577 0,10168902 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04657577 0,10159682 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04657577 0,1015048 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04657577 0,10141294 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04657577 0,10132124 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04657577 0,10122972 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04657577 0,10113835 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04657577 0,10104715 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04657577 0,10095612 ! hormone catabolic process GO:0042447 17 8 0,000 0,04657577 0,10086525 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04657577 0,10077455 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04657577 0,100684 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04657577 0,10059362 ! ATP catabolic process GO:0006200 11 8 0,000 0,04657577 0,1005034 ! blastocyst growth GO:0001832 19 8 0,000 0,04657577 0,10041335 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04657577 0,10032345 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04657577 0,10023372 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04657577 0,10014414 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04657577 0,10005473 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04657577 0,09996547 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04657577 0,09987638 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04657577 0,09978744 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04657577 0,09969866 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04657577 0,09961004 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04657577 0,09952158 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04657577 0,09943327 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04657577 0,09934512 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04657577 0,09925713 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04657577 0,09916929 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04657577 0,0990816 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04657577 0,09899408 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04674156 0,09925879 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04819713 0,10225951 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,04966907 0,10528967 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,04966907 0,10519699 ! regulation of heart contraction GO:0008016 110 60 1,000 0,04966907 0,10510446 ! camera-type eye development GO:0043010 116 60 1,000 0,04966907 0,10501211 ! kidney development GO:0001822 122 60 1,000 0,04966907 0,10491991 ! axon extension GO:0048675 15 9 0,000 0,05224394 0,1102622 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05224394 0,11016557 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05224394 0,1100691 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05224394 0,1099728 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05224394 0,10987667 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05224394 0,10978071 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05224394 0,10968491 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05224394 0,10958929 ! phosphate transport GO:0006817 19 9 0,000 0,05224394 0,10949383 ! reproductive behavior GO:0019098 19 9 0,000 0,05224394 0,10939853 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05224394 0,1093034 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05224394 0,10920844 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05224394 0,10911364 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05224394 0,109019 ! GTP metabolic process GO:0046039 9 9 0,000 0,05224394 0,10892453 ! RNA methylation GO:0001510 15 9 0,000 0,05224394 0,10883023 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05224394 0,10873608 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05224394 0,1086421 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05224394 0,10854828 ! artery development GO:0060840 24 9 0,000 0,05224394 0,10845463 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05224394 0,10836113 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05224394 0,1082678 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05224394 0,10817462 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05224394 0,10808161 ! chemosensory behavior GO:0007635 20 9 0,000 0,05224394 0,10798876 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05224394 0,10789606 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05224394 0,10780353 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05224394 0,10771115 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05224394 0,10761893 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05224394 0,10752687 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05224394 0,10743497 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05224394 0,10734322 ! protein targeting to ER GO:0045047 22 9 0,000 0,05224394 0,10725163 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05224394 0,1071602 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05224394 0,10706892 ! T cell selection GO:0045058 23 9 0,000 0,05224394 0,1069778 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05224394 0,10688683 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05224394 0,10679602 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05224394 0,10670536 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05224394 0,10661485 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05224394 0,1065245 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05224394 0,1064343 ! mannose metabolic process GO:0006013 13 9 0,000 0,05224394 0,10634426 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05224394 0,10625436 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05224394 0,10616462 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05224394 0,10607503 ! receptor clustering GO:0043113 18 9 0,000 0,05224394 0,10598559 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05224394 0,1058963 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05224394 0,10580717 ! ruffle organization GO:0031529 15 9 0,000 0,05224394 0,10571818 ! retinol metabolic process GO:0042572 18 9 0,000 0,05224394 0,10562934 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05224394 0,10554065 ! behavioral fear response GO:0001662 22 9 0,000 0,05224394 0,10545211 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05224394 0,10536372 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05224394 0,10527547 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05224394 0,10518737 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05224394 0,10509942 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05224394 0,10501162 ! segment specification GO:0007379 13 9 0,000 0,05224394 0,10492397 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05224394 0,10483646 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05224394 0,10474909 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05224394 0,10466188 ! response to amine stimulus GO:0014075 13 9 0,000 0,05224394 0,1045748 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05224394 0,10448787 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05224394 0,10440109 ! erythrocyte development GO:0048821 15 9 0,000 0,05224394 0,10431445 ! gas homeostasis GO:0033483 16 9 0,000 0,05224394 0,10422795 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05224394 0,1041416 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05224394 0,10405539 ! renal water homeostasis GO:0003091 14 9 0,000 0,05224394 0,10396932 ! postreplication repair GO:0006301 22 9 0,000 0,05224394 0,1038834 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05224394 0,10379762 ! icosanoid secretion GO:0032309 15 9 0,000 0,05224394 0,10371197 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05224394 0,10362647 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05224394 0,10354111 ! regulation of cell division GO:0051302 15 9 0,000 0,05224394 0,10345589 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05224394 0,10337082 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05224394 0,10328588 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05224394 0,10320108 ! sterol catabolic process GO:0016127 11 9 0,000 0,05224394 0,10311642 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05224394 0,1030319 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05224394 0,10294751 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05224394 0,10286327 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05224394 0,10277916 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05224394 0,10269519 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05224394 0,10261136 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05224394 0,10252766 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05224394 0,1024441 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05224394 0,10236068 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05224394 0,10227739 ! purine base metabolic process GO:0006144 21 9 0,000 0,05224394 0,10219424 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05224394 0,10211122 ! pigment granule transport GO:0051904 17 9 0,000 0,05224394 0,10202834 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05224394 0,10194559 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05224394 0,10186298 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05224394 0,1017805 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05224394 0,10169815 ! mitochondrion localization GO:0051646 15 9 0,000 0,05224394 0,10161594 ! viral reproductive process GO:0022415 126 62 1,000 0,05266111 0,1023446 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,05266111 0,102262 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,05418072 0,10512808 ! detection of external stimulus GO:0009581 91 63 1,000 0,05418072 0,10504337 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05418072 0,10495879 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05726597 0,11084628 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0578786 0,11194204 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0578786 0,11185213 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0578786 0,11176236 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0578786 0,11167274 ! synapsis GO:0007129 13 10 0,000 0,0578786 0,11158326 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0578786 0,11149392 ! N-glycan processing GO:0006491 20 10 0,000 0,0578786 0,11140472 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0578786 0,11131567 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0578786 0,11122676 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0578786 0,11113799 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0578786 0,11104936 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0578786 0,11096088 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0578786 0,11087253 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0578786 0,11078433 ! androgen metabolic process GO:0008209 17 10 0,000 0,0578786 0,11069627 ! phospholipid efflux GO:0033700 16 10 0,000 0,0578786 0,11060834 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0578786 0,11052056 ! lung alveolus development GO:0048286 26 10 0,000 0,0578786 0,11043291 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0578786 0,11034541 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0578786 0,11025804 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0578786 0,11017081 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0578786 0,11008372 ! endoderm development GO:0007492 16 10 0,000 0,0578786 0,10999676 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0578786 0,10990995 ! arginine catabolic process GO:0006527 13 10 0,000 0,0578786 0,10982327 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0578786 0,10973672 ! proline metabolic process GO:0006560 13 10 0,000 0,0578786 0,10965032 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0578786 0,10956405 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0578786 0,10947791 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0578786 0,10939191 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0578786 0,10930605 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0578786 0,10922032 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0578786 0,10913472 ! B cell proliferation GO:0042100 18 10 0,000 0,0578786 0,10904926 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0578786 0,10896393 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0578786 0,10887874 ! multicellular organism growth GO:0035264 18 10 0,000 0,0578786 0,10879367 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0578786 0,10870875 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0578786 0,10862395 ! epithelial cell development GO:0002064 20 10 0,000 0,0578786 0,10853929 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0578786 0,10845475 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0578786 0,10837035 ! macroautophagy GO:0016236 17 10 0,000 0,0578786 0,10828608 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0578786 0,10820195 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0578786 0,10811794 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0578786 0,10803406 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0578786 0,10795031 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0578786 0,1078667 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0578786 0,10778321 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0578786 0,10769985 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0578786 0,10761662 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0578786 0,10753352 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0578786 0,10745054 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0578786 0,1073677 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0578786 0,10728498 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0578786 0,10720239 ! response to dsRNA GO:0043331 20 10 0,000 0,0578786 0,10711993 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0578786 0,10703759 ! melanosome localization GO:0032400 16 10 0,000 0,0578786 0,10695538 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0578786 0,1068733 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0578786 0,10679134 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0578786 0,1067095 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0578786 0,1066278 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0578786 0,10654622 ! mRNA cleavage GO:0006379 17 10 0,000 0,0578786 0,10646476 ! protein sumoylation GO:0016925 15 10 0,000 0,0578786 0,10638343 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0578786 0,10630222 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0578786 0,10622113 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0578786 0,10614017 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0578786 0,10605933 ! salivary gland development GO:0007431 27 10 0,000 0,0578786 0,10597862 ! prophase GO:0051324 15 10 0,000 0,0578786 0,10589803 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0578786 0,10581756 ! apical protein localization GO:0045176 15 10 0,000 0,0578786 0,10573721 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0578786 0,10565698 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0578786 0,10557688 ! midbrain development GO:0030901 13 10 0,000 0,0578786 0,1054969 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0578786 0,10541704 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0578786 0,10533729 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0578786 0,10525767 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0578786 0,10517817 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0578786 0,1050988 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0578786 0,10501954 ! detection of calcium ion GO:0005513 23 10 0,000 0,0578786 0,10494039 ! oocyte development GO:0048599 17 10 0,000 0,0578786 0,10486137 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0578786 0,10478247 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0578786 0,10470369 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0578786 0,10462502 ! activation of innate immune response GO:0002218 12 10 0,000 0,0578786 0,10454647 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0578786 0,10446804 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0578786 0,10438973 ! response to nicotine GO:0035094 20 10 0,000 0,0578786 0,10431154 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0578786 0,10423346 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0578786 0,1041555 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0578786 0,10407766 ! extracellular matrix organization GO:0030198 133 66 1,000 0,05883114 0,10571151 ! cell projection assembly GO:0030031 120 66 1,000 0,05883114 0,10563262 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06041102 0,10838845 ! chromosome segregation GO:0007059 113 67 1,000 0,06041102 0,10830769 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,06041102 0,10822704 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,06041102 0,10814651 ! adaptive immune response GO:0002250 119 67 1,000 0,06041102 0,10806611 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,06200539 0,11083579 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06200539 0,11075351 ! viral reproduction GO:0016032 134 68 1,000 0,06200539 0,11067135 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06200539 0,11058931 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06200539 0,11050739 ! respiratory burst GO:0045730 17 11 0,000 0,06347994 0,11305162 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06347994 0,112968 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06347994 0,11288451 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06347994 0,11280114 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06347994 0,11271789 ! thyroid gland development GO:0030878 26 11 0,000 0,06347994 0,11263477 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06347994 0,11255176 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06347994 0,11246888 ! response to pain GO:0048265 24 11 0,000 0,06347994 0,11238612 ! T cell proliferation GO:0042098 26 11 0,000 0,06347994 0,11230349 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06347994 0,11222097 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06347994 0,11213858 ! bone resorption GO:0045453 16 11 0,000 0,06347994 0,1120563 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06347994 0,11197415 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06347994 0,11189212 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06347994 0,11181021 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06347994 0,11172841 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06347994 0,11164674 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06347994 0,11156519 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06347994 0,11148375 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06347994 0,11140244 ! lipid digestion GO:0044241 18 11 0,000 0,06347994 0,11132124 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06347994 0,11124016 ! adult heart development GO:0007512 14 11 0,000 0,06347994 0,1111592 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06347994 0,11107836 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06347994 0,11099763 ! temperature homeostasis GO:0001659 17 11 0,000 0,06347994 0,11091702 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06347994 0,11083653 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06347994 0,11075616 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06347994 0,1106759 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06347994 0,11059576 ! regulation of organ growth GO:0046620 13 11 0,000 0,06347994 0,11051573 ! pigment granule localization GO:0051875 20 11 0,000 0,06347994 0,11043582 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06347994 0,11035603 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06347994 0,11027635 ! embryonic axis specification GO:0000578 18 11 0,000 0,06347994 0,11019678 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06347994 0,11011733 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06347994 0,110038 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06347994 0,10995878 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06347994 0,10987967 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06347994 0,10980068 ! zymogen activation GO:0031638 15 11 0,000 0,06347994 0,1097218 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06347994 0,10964303 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06347994 0,10956438 ! nucleosome positioning GO:0016584 15 11 0,000 0,06347994 0,10948584 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06347994 0,10940741 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06347994 0,10932909 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06347994 0,10925089 ! acid secretion GO:0046717 18 11 0,000 0,06347994 0,1091728 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06347994 0,10909482 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06347994 0,10901695 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06347994 0,10893919 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06347994 0,10886154 ! oocyte differentiation GO:0009994 18 11 0,000 0,06347994 0,108784 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06347994 0,10870658 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06347994 0,10862926 ! cholesterol efflux GO:0033344 19 11 0,000 0,06347994 0,10855206 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06347994 0,10847496 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06347994 0,10839797 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06347994 0,10832109 GO:0010829|negative regulation of glucose transport, ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06347994 0,10824433 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06347994 0,10816766 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06347994 0,10809111 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06347994 0,10801467 ! defense response to fungus GO:0050832 13 11 0,000 0,06347994 0,10793833 ! lysogeny GO:0030069 21 11 0,000 0,06347994 0,10786211 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06347994 0,10778599 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06347994 0,10770997 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06347994 0,10763407 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06347994 0,10755827 ! nucleus localization GO:0051647 19 11 0,000 0,06347994 0,10748258 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06347994 0,10740699 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,06361403 0,10755823 ! urogenital system development GO:0001655 137 69 1,000 0,06361403 0,1074827 ! antigen processing and presentation GO:0019882 104 69 1,000 0,06361403 0,10740727 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06852331 0,11561507 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06904817 0,11641899 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06904817 0,11633747 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06904817 0,11625605 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06904817 0,11617476 ! cartilage condensation GO:0001502 20 12 0,000 0,06904817 0,11609357 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06904817 0,1160125 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06904817 0,11593154 ! protein complex disassembly GO:0043241 27 12 0,000 0,06904817 0,1158507 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06904817 0,11576997 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06904817 0,11568935 ! hippocampus development GO:0021766 26 12 0,000 0,06904817 0,11560884 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06904817 0,11552844 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06904817 0,11544816 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06904817 0,11536799 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06904817 0,11528793 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06904817 0,11520798 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06904817 0,11512814 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06904817 0,11504841 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06904817 0,11496879 ! drug transport GO:0015893 16 12 0,000 0,06904817 0,11488928 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06904817 0,11480988 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06904817 0,11473059 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06904817 0,11465142 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06904817 0,11457235 ! focal adhesion formation GO:0048041 35 12 0,000 0,06904817 0,11449338 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06904817 0,11441453 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06904817 0,11433579 ! forebrain cell migration GO:0021885 21 12 0,000 0,06904817 0,11425715 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06904817 0,11417863 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06904817 0,11410021 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06904817 0,11402189 ! entry into host cell GO:0030260 32 12 0,000 0,06904817 0,11394369 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06904817 0,11386559 ! monoamine transport GO:0015844 18 12 0,000 0,06904817 0,1137876 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06904817 0,11370972 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06904817 0,11363194 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06904817 0,11355427 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06904817 0,11347671 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06904817 0,11339925 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06904817 0,1133219 ! protein homotetramerization GO:0051289 21 12 0,000 0,06904817 0,11324465 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06904817 0,11316751 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06904817 0,11309047 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06904817 0,11301354 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06904817 0,11293671 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06904817 0,11285999 ! fucose catabolic process GO:0019317 22 12 0,000 0,06904817 0,11278337 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06904817 0,11270685 ! histone methylation GO:0016571 26 12 0,000 0,06904817 0,11263044 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06904817 0,11255413 ! gland morphogenesis GO:0022612 29 12 0,000 0,06904817 0,11247793 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06904817 0,11240183 ! T cell homeostasis GO:0043029 25 12 0,000 0,06904817 0,11232583 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06904817 0,11224993 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06904817 0,11217414 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06904817 0,11209845 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06904817 0,11202286 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06904817 0,11194737 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06904817 0,11187199 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06904817 0,1117967 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06904817 0,11172152 ! response to cold GO:0009409 17 12 0,000 0,06904817 0,11164644 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06904817 0,11157146 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06904817 0,11149658 ! learning or memory GO:0007611 147 73 1,000 0,0701868 0,11325918 ! regulation of blood pressure GO:0008217 125 73 1,000 0,0701868 0,11318327 ! transition metal ion transport GO:0000041 126 74 1,000 0,07186345 0,11580941 ! neurotransmitter transport GO:0006836 123 74 1,000 0,07186345 0,1157319 ! meiosis GO:0007126 121 74 1,000 0,07186345 0,11565448 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,07186345 0,11557717 ! eye development GO:0001654 143 74 1,000 0,07186345 0,11549997 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07355305 0,11813661 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,07355305 0,1180578 ! meiotic cell cycle GO:0051321 122 75 1,000 0,07355305 0,1179791 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07458348 0,1195522 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07458348 0,1194726 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07458348 0,11939311 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07458348 0,11931373 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07458348 0,11923445 ! lipid localization GO:0010876 28 13 0,000 0,07458348 0,11915528 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07458348 0,11907621 ! organelle fusion GO:0048284 32 13 0,000 0,07458348 0,11899725 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07458348 0,11891839 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07458348 0,11883963 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07458348 0,11876098 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07458348 0,11868244 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07458348 0,118604 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07458348 0,11852566 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07458348 0,11844742 ! methionine metabolic process GO:0006555 27 13 0,000 0,07458348 0,11836929 ! plasma membrane organization GO:0007009 24 13 0,000 0,07458348 0,11829126 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07458348 0,11821334 ! Golgi organization GO:0007030 24 13 0,000 0,07458348 0,11813551 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07458348 0,11805779 ! response to X-ray GO:0010165 25 13 0,000 0,07458348 0,11798017 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07458348 0,11790266 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07458348 0,11782524 ! exocrine system development GO:0035272 32 13 0,000 0,07458348 0,11774793 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07458348 0,11767072 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07458348 0,11759361 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07458348 0,1175166 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07458348 0,11743969 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07458348 0,11736288 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07458348 0,11728617 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07458348 0,11720957 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07458348 0,11713306 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07458348 0,11705665 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07458348 0,11698034 ! ribosome assembly GO:0042255 17 13 0,000 0,07458348 0,11690413 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07458348 0,11682802 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07458348 0,11675201 ! chromatin silencing GO:0006342 26 13 0,000 0,07458348 0,1166761 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07458348 0,11660029 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07458348 0,11652458 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07458348 0,11644896 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07458348 0,11637344 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07458348 0,11629802 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07458348 0,1162227 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07458348 0,11614747 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07458348 0,11607235 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07458348 0,11599731 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07458348 0,11592238 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07458348 0,11584754 ! embryonic placenta development GO:0001892 23 13 0,000 0,07458348 0,1157728 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07458348 0,11569816 ! insulin secretion GO:0030073 23 13 0,000 0,07458348 0,11562361 ! actin filament polymerization GO:0030041 24 13 0,000 0,07458348 0,11554916 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07458348 0,1154748 ! acrosome reaction GO:0007340 18 13 0,000 0,07458348 0,11540054 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,0752554 0,11636536 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,07869749 0,12160961 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07869749 0,12153156 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,07869749 0,1214536 ! protein oligomerization GO:0051259 139 78 1,000 0,07869749 0,12137575 ! rRNA transcription GO:0009303 25 14 0,000 0,08008605 0,12343821 ! lactation GO:0007595 26 14 0,000 0,08008605 0,12335918 ! reproductive cellular process GO:0048610 20 14 0,000 0,08008605 0,12328026 ! tRNA modification GO:0006400 20 14 0,000 0,08008605 0,12320144 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08008605 0,12312271 ! regulation of S phase GO:0033261 23 14 0,000 0,08008605 0,12304409 ! water transport GO:0006833 21 14 0,000 0,08008605 0,12296557 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08008605 0,12288715 ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08008605 0,12280882 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08008605 0,1227306 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08008605 0,12265248 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08008605 0,12257446 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08008605 0,12249653 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08008605 0,12241871 ! palate development GO:0060021 31 14 0,000 0,08008605 0,12234098 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08008605 0,12226335 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08008605 0,12218582 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08008605 0,12210839 ! arginine metabolic process GO:0006525 17 14 0,000 0,08008605 0,12203106 ! organic alcohol transport GO:0015850 29 14 0,000 0,08008605 0,12195383 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08008605 0,12187669 ! embryo implantation GO:0007566 30 14 0,000 0,08008605 0,12179965 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08008605 0,12172271 ! L-amino acid transport GO:0015807 30 14 0,000 0,08008605 0,12164586 ! bone mineralization GO:0030282 17 14 0,000 0,08008605 0,12156911 ! stem cell development GO:0048864 43 14 0,000 0,08008605 0,12149246 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08008605 0,12141591 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08008605 0,12133945 ! cerebellum development GO:0021549 21 14 0,000 0,08008605 0,12126309 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08008605 0,12118682 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08008605 0,12111065 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08008605 0,12103458 ! cofactor transport GO:0051181 26 14 0,000 0,08008605 0,1209586 ! NADP metabolic process GO:0006739 24 14 0,000 0,08008605 0,12088271 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08008605 0,12080692 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08008605 0,12073123 ! intestinal absorption GO:0050892 25 14 0,000 0,08008605 0,12065563 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08008605 0,12058013 ! oxygen transport GO:0015671 21 14 0,000 0,08008605 0,12050472 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08008605 0,1204294 ! male genitalia development GO:0030539 24 14 0,000 0,08008605 0,12035418 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08008605 0,12027905 ! regulation of axon extension GO:0030516 37 14 0,000 0,08008605 0,12020402 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08008605 0,12012908 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,08043682 0,12058006 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,08043682 0,12050498 ! response to metal ion GO:0010038 140 80 1,000 0,08218807 0,12305196 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,08395104 0,12561331 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 1,000 0,08395104 0,12553524 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08395104 0,12545727 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,08395104 0,1253794 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08555609 0,12769725 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08555609 0,12761808 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08555609 0,12753901 ! superoxide anion generation GO:0042554 20 15 0,000 0,08555609 0,12746004 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,08555609 0,12738116 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08555609 0,12730239 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08555609 0,12722371 ! copper ion transport GO:0006825 20 15 0,000 0,08555609 0,12714513 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08555609 0,12706664 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08555609 0,12698825 ! sulfate transport GO:0008272 23 15 0,000 0,08555609 0,12690996 ! response to cAMP GO:0051591 22 15 0,000 0,08555609 0,12683177 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08555609 0,12675367 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08555609 0,12667567 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08555609 0,12659776 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08555609 0,12651995 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08555609 0,12644224 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08555609 0,12636462 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08555609 0,12628709 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08555609 0,12620966 ! pituitary gland development GO:0021983 29 15 0,000 0,08555609 0,12613233 ! vesicle coating GO:0006901 33 15 0,000 0,08555609 0,12605509 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08555609 0,12597794 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08555609 0,12590089 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08555609 0,12582394 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08555609 0,12574707 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08555609 0,1256703 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08555609 0,12559363 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08555609 0,12551705 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08555609 0,12544056 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08555609 0,12536417 ! histone deacetylation GO:0016575 20 15 0,000 0,08555609 0,12528786 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08555609 0,12521165 ! tissue regeneration GO:0042246 26 15 0,000 0,08555609 0,12513554 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08555609 0,12505951 ! water homeostasis GO:0030104 27 15 0,000 0,08555609 0,12498358 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08555609 0,12490774 ! muscle maintenance GO:0046716 26 15 0,000 0,08555609 0,12483199 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08555609 0,12475634 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08555609 0,12468077 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08555609 0,1246053 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08555609 0,12452992 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08555609 0,12445463 ! cell killing GO:0001906 29 15 0,000 0,08555609 0,12437943 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08555609 0,12430432 ! detection of bacterium GO:0016045 18 15 0,000 0,08555609 0,12422931 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08555609 0,12415438 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08555609 0,12407954 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08555609 0,12400479 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08555609 0,12393014 ! peptide hormone processing GO:0016486 23 15 0,000 0,08555609 0,12385557 ! response to drug GO:0042493 143 82 1,000 0,08572553 0,12402623 ! response to nutrient GO:0007584 125 82 1,000 0,08572553 0,12395169 ! negative regulation of transport GO:0051051 153 84 1,000 0,08930827 0,12905447 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,08930827 0,128977 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09099379 0,13133236 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09099379 0,13125363 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09099379 0,13117499 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09099379 0,13109644 ! bone remodeling GO:0046849 27 16 0,000 0,09099379 0,13101798 ! filopodium assembly GO:0046847 32 16 0,000 0,09099379 0,13093962 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09099379 0,13086136 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09099379 0,13078318 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09099379 0,1307051 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09099379 0,13062712 ! startle response GO:0001964 28 16 0,000 0,09099379 0,13054923 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09099379 0,13047142 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09099379 0,13039372 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09099379 0,1303161 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09099379 0,13023858 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09099379 0,13016115 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09099379 0,13008381 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09099379 0,13000656 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09099379 0,12992941 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09099379 0,12985234 ! response to osmotic stress GO:0006970 25 16 0,000 0,09099379 0,12977537 ! lysosomal transport GO:0007041 26 16 0,000 0,09099379 0,12969849 ! fructose metabolic process GO:0006000 25 16 0,000 0,09099379 0,1296217 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09099379 0,129545 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09099379 0,12946839 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09099379 0,12939187 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09099379 0,12931545 ! axon cargo transport GO:0008088 43 16 0,000 0,09099379 0,12923911 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09099379 0,12916286 ! DNA replication initiation GO:0006270 27 16 0,000 0,09099379 0,1290867 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09099379 0,12901064 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09099379 0,12893466 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09099379 0,12885877 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09099379 0,12878297 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,09099379 0,12870726 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09099379 0,12863164 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09099379 0,12855611 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09099379 0,12848066 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09099379 0,12840531 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09099379 0,12833004 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09099379 0,12825486 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09099379 0,12817977 ! defense response to virus GO:0051607 37 16 0,000 0,09099379 0,12810477 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,09111613 0,12820199 ! amine biosynthetic process GO:0009309 138 86 1,000 0,09293473 0,13068438 ! response to inorganic substance GO:0010035 153 86 1,000 0,09293473 0,13060804 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,09476389 0,13310094 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09639933 0,13531901 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09639933 0,1352401 ! metencephalon development GO:0022037 30 17 0,000 0,09639933 0,13516129 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09639933 0,13508257 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,09639933 0,13500394 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09639933 0,13492541 ! signal complex assembly GO:0007172 41 17 0,000 0,09639933 0,13484696 ! endothelial cell migration GO:0043542 28 17 0,000 0,09639933 0,13476861 ! inositol metabolic process GO:0006020 28 17 0,000 0,09639933 0,13469035 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09639933 0,13461217 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09639933 0,13453409 ! glial cell development GO:0021782 27 17 0,000 0,09639933 0,1344561 ! limbic system development GO:0021761 36 17 0,000 0,09639933 0,1343782 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09639933 0,13430039 ! adult walking behavior GO:0007628 33 17 0,000 0,09639933 0,13422267 ! heart looping GO:0001947 30 17 0,000 0,09639933 0,13414504 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09639933 0,1340675 ! myoblast differentiation GO:0045445 45 17 0,000 0,09639933 0,13399005 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09639933 0,13391269 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09639933 0,13383542 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09639933 0,13375823 ! glycine metabolic process GO:0006544 28 17 0,000 0,09639933 0,13368114 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09639933 0,13360413 ! NAD metabolic process GO:0019674 29 17 0,000 0,09639933 0,13352722 ! membrane budding GO:0006900 37 17 0,000 0,09639933 0,13345039 ! DNA integration GO:0015074 29 17 0,000 0,09639933 0,13337365 ! regulation of protein binding GO:0043393 33 17 0,000 0,09639933 0,133297 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09639933 0,13322043 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09639933 0,13314396 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09639933 0,13306757 ! genitalia development GO:0048806 30 17 0,000 0,09639933 0,13299127 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09639933 0,13291506 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09639933 0,13283893 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09639933 0,13276289 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09639933 0,13268694 ! steroid catabolic process GO:0006706 31 17 0,000 0,09639933 0,13261108 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09639933 0,1325353 ! gas transport GO:0015669 25 17 0,000 0,09639933 0,13245961 ! organic cation transport GO:0015695 31 17 0,000 0,09639933 0,132384 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09639933 0,13230849 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,09639933 0,13223305 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09639933 0,13215771 ! microspike assembly GO:0030035 36 17 0,000 0,09639933 0,13208245 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09639933 0,13200727 ! regulation of neurological system process GO:0031644 148 88 1,000 0,09660341 0,13221149 ! ossification GO:0001503 188 90 1,000 0,10031279 0,1372101 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,10031279 0,13713214 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1017729 0,13904917 ! neuron maturation GO:0042551 42 18 0,000 0,1017729 0,13897026 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1017729 0,13889143 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1017729 0,13881269 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1017729 0,13873405 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1017729 0,13865549 ! memory GO:0007613 31 18 0,000 0,1017729 0,13857702 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1017729 0,13849864 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1017729 0,13842035 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1017729 0,13834214 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,1017729 0,13826403 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1017729 0,138186 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,1017729 0,13810806 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1017729 0,13803021 ! response to retinoic acid GO:0032526 26 18 0,000 0,1017729 0,13795245 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,1017729 0,13787477 ! response to fungus GO:0009620 21 18 0,000 0,1017729 0,13779718 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,1017729 0,13771968 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,1017729 0,13764227 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1017729 0,13756494 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,1017729 0,1374877 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1017729 0,13741054 ! vitamin transport GO:0051180 27 18 0,000 0,1017729 0,13733348 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1017729 0,1372565 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1017729 0,1371796 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,1017729 0,13710279 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1017729 0,13702607 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1017729 0,13694944 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1017729 0,13687288 ! bone development GO:0060348 189 91 1,000 0,10218228 0,13734669 ! regulation of defense response GO:0031347 149 92 1,000 0,10406141 0,13979439 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,10594998 0,14225204 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 1,000 0,10594998 0,1421727 ! protein secretion GO:0009306 39 19 0,000 0,10711469 0,14365549 ! positive regulation of translation GO:0045727 30 19 0,000 0,10711469 0,14357546 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10711469 0,14349552 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10711469 0,14341566 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10711469 0,1433359 ! skin development GO:0043588 36 19 0,000 0,10711469 0,14325622 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10711469 0,14317664 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10711469 0,14309714 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10711469 0,14301773 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10711469 0,14293841 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10711469 0,14285917 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10711469 0,14278003 ! cerebral cortex development GO:0021987 36 19 0,000 0,10711469 0,14270097 ! pigmentation during development GO:0048066 41 19 0,000 0,10711469 0,142622 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10711469 0,14254311 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10711469 0,14246432 ! heme metabolic process GO:0042168 36 19 0,000 0,10711469 0,14238561 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10711469 0,14230698 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10711469 0,14222845 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10711469 0,14215 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10711469 0,14207164 ! protein export from nucleus GO:0006611 36 19 0,000 0,10711469 0,14199336 ! heart process GO:0003015 30 19 0,000 0,10711469 0,14191517 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10711469 0,14183706 ! visual learning GO:0008542 36 19 0,000 0,10711469 0,14175905 ! cellular pigmentation GO:0033059 36 19 0,000 0,10711469 0,14168111 ! G1 phase GO:0051318 40 19 0,000 0,10711469 0,14160327 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10711469 0,14152551 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10711469 0,14144783 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10711469 0,14137024 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10711469 0,14129273 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10711469 0,14121531 ! cilium assembly GO:0042384 37 19 0,000 0,10711469 0,14113798 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10711469 0,14106073 ! mRNA transport GO:0051028 169 96 1,000 0,11167065 0,14698008 ! detection of stimulus GO:0051606 151 96 1,000 0,11167065 0,14689972 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11242489 0,14781109 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11242489 0,14773036 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11242489 0,14764972 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11242489 0,14756917 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11242489 0,14748871 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11242489 0,14740833 ! response to vitamin GO:0033273 31 20 0,000 0,11242489 0,14732805 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11242489 0,14724785 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11242489 0,14716773 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11242489 0,14708771 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11242489 0,14700777 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11242489 0,14692792 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11242489 0,14684815 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11242489 0,14676847 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11242489 0,14668888 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11242489 0,14660937 ! body fluid secretion GO:0007589 31 20 0,000 0,11242489 0,14652995 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11242489 0,14645062 ! peptide secretion GO:0002790 35 20 0,000 0,11242489 0,14637137 ! stem cell differentiation GO:0048863 53 20 0,000 0,11242489 0,14629221 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11242489 0,14621313 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11242489 0,14613414 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11242489 0,14605523 ! sensory perception of pain GO:0019233 30 20 0,000 0,11242489 0,14597641 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11242489 0,14589768 ! diencephalon development GO:0021536 34 20 0,000 0,11242489 0,14581903 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11242489 0,14574046 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11242489 0,14566198 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11242489 0,14558358 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11242489 0,14550527 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11242489 0,14542704 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11242489 0,14534889 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11242489 0,14527083 ! regulation of glucose import GO:0046324 29 20 0,000 0,11242489 0,14519286 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11242489 0,14511496 ! actin filament-based movement GO:0030048 43 20 0,000 0,11242489 0,14503715 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11242489 0,14495943 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11242489 0,14488179 ! negative regulation of translation GO:0017148 29 20 0,000 0,11242489 0,14480423 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11242489 0,14472675 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11242489 0,14464935 ! protein ubiquitination GO:0016567 217 97 1,000 0,11359527 0,14607709 ! regulation of cell killing GO:0031341 42 21 0,000 0,11770369 0,15127942 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11770369 0,15119865 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11770369 0,15111797 ! hormone secretion GO:0046879 38 21 0,000 0,11770369 0,15103738 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11770369 0,15095686 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11770369 0,15087644 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11770369 0,1507961 ! axis specification GO:0009798 38 21 0,000 0,11770369 0,15071585 ! ovarian follicle development GO:0001541 35 21 0,000 0,11770369 0,15063568 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11770369 0,1505556 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11770369 0,1504756 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11770369 0,15039569 ! cell aging GO:0007569 44 21 0,000 0,11770369 0,15031586 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11770369 0,15023612 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11770369 0,15015646 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11770369 0,15007688 ! cytolysis GO:0019835 24 21 0,000 0,11770369 0,14999739 ! vasodilation GO:0042311 39 21 0,000 0,11770369 0,14991799 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11770369 0,14983867 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11770369 0,14975943 ! oogenesis GO:0048477 36 21 0,000 0,11770369 0,14968027 ! collagen fibril organization GO:0030199 59 21 0,000 0,11770369 0,1496012 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11770369 0,14952222 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11770369 0,14944331 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11770369 0,14936449 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11770369 0,14928576 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11770369 0,1492071 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11770369 0,14912853 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11770369 0,14905004 ! collagen catabolic process GO:0030574 28 21 0,000 0,11770369 0,14897164 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11770369 0,14889331 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12295127 0,15544968 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12295127 0,15536804 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12295127 0,15528648 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12295127 0,15520501 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12295127 0,15512362 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12295127 0,15504232 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12295127 0,1549611 ! regeneration GO:0031099 41 22 0,000 0,12295127 0,15487997 ! keratinization GO:0031424 28 22 0,000 0,12295127 0,15479892 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12295127 0,15471796 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12295127 0,15463709 ! sensory perception of taste GO:0050909 28 22 0,000 0,12295127 0,15455629 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12295127 0,15447559 ! vacuolar transport GO:0007034 36 22 0,000 0,12295127 0,15439496 ! lysosome organization GO:0007040 41 22 0,000 0,12295127 0,15431442 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12295127 0,15423397 ! fucose metabolic process GO:0006004 39 22 0,000 0,12295127 0,15415359 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12295127 0,15407331 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12295127 0,1539931 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12295127 0,15391298 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12295127 0,15383294 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12295127 0,15375299 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12295127 0,15367311 ! sarcomere organization GO:0045214 30 22 0,000 0,12295127 0,15359333 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12295127 0,15351362 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12295127 0,153434 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,12295127 0,15335446 ! protein stabilization GO:0050821 39 22 0,000 0,12295127 0,153275 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1281678 0,15969536 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1281678 0,1596127 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1281678 0,15953013 ! gluconeogenesis GO:0006094 33 23 0,000 0,1281678 0,15944764 ! viral genome replication GO:0019079 41 23 0,000 0,1281678 0,15936524 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1281678 0,15928292 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1281678 0,15920069 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1281678 0,15911854 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1281678 0,15903648 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1281678 0,1589545 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1281678 0,15887261 ! visual behavior GO:0007632 42 23 0,000 0,1281678 0,1587908 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1281678 0,15870908 ! response to ethanol GO:0045471 46 23 0,000 0,1281678 0,15862744 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1281678 0,15854588 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1281678 0,15846441 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1281678 0,15838302 ! vesicle targeting GO:0006903 43 23 0,000 0,1281678 0,15830171 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1281678 0,15822049 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,1281678 0,15813935 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1281678 0,1580583 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1281678 0,15797732 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1281678 0,15789643 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1281678 0,15781563 ! fatty acid transport GO:0015908 44 23 0,000 0,1281678 0,1577349 ! platelet activation GO:0030168 37 23 0,000 0,1281678 0,15765426 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1281678 0,1575737 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1281678 0,15749323 ! hormone transport GO:0009914 40 23 0,000 0,1281678 0,15741283 ! cell-cell recognition GO:0009988 25 23 0,000 0,1281678 0,15733252 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1281678 0,15725229 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1281678 0,15717214 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1281678 0,15709207 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1281678 0,15701209 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13335349 0,16328168 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13335349 0,16319862 ! vesicle docking GO:0048278 47 24 0,000 0,13335349 0,16311565 ! vacuole organization GO:0007033 43 24 0,000 0,13335349 0,16303277 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13335349 0,16294997 ! digestive system process GO:0022600 39 24 0,000 0,13335349 0,16286725 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13335349 0,16278462 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13335349 0,16270207 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13335349 0,16261961 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13335349 0,16253723 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13335349 0,16245493 ! membrane depolarization GO:0051899 39 24 0,000 0,13335349 0,16237272 ! pallium development GO:0021543 49 24 0,000 0,13335349 0,16229059 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,13335349 0,16220854 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13335349 0,16212657 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13335349 0,16204469 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13335349 0,16196289 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13335349 0,16188118 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13335349 0,16179954 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13335349 0,16171799 ! regulation of amine transport GO:0051952 40 24 0,000 0,13335349 0,16163652 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,1385085 0,16780033 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,1385085 0,16771588 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,1385085 0,16763151 ! phototransduction GO:0007602 33 25 0,000 0,1385085 0,16754723 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,1385085 0,16746304 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,1385085 0,16737893 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,1385085 0,1672949 ! sperm motility GO:0030317 31 25 0,000 0,1385085 0,16721096 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,1385085 0,1671271 ! receptor metabolic process GO:0043112 46 25 0,000 0,1385085 0,16704333 ! osteoblast differentiation GO:0001649 60 25 0,000 0,1385085 0,16695964 ! neural crest cell development GO:0014032 54 25 0,000 0,1385085 0,16687604 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,1385085 0,16679252 ! negative regulation of cell development GO:0010721 73 25 0,000 0,1385085 0,16670908 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,1385085 0,16662572 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,1385085 0,16654245 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,1385085 0,16645926 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,1385085 0,16637616 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,1385085 0,16629314 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,1385085 0,1662102 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,1385085 0,16612734 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14363302 0,17218786 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14363302 0,17210211 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14363302 0,17201644 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14363302 0,17193086 ! initiation of viral infection GO:0019059 57 26 0,000 0,14363302 0,17184537 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14363302 0,17175996 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14363302 0,17167463 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14363302 0,17158939 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14363302 0,17150424 ! molting cycle process GO:0022404 50 26 0,000 0,14363302 0,17141916 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14363302 0,17133418 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,14363302 0,17124927 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14363302 0,17116446 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14363302 0,17107972 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14363302 0,17099507 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14363302 0,1709105 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14363302 0,17082602 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,14363302 0,17074162 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14363302 0,1706573 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14363302 0,17057307 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14363302 0,17048892 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14363302 0,17040485 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14363302 0,17032087 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14872722 0,17627472 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14872722 0,17618793 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14872722 0,17610123 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14872722 0,1760146 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14872722 0,17592807 ! fat cell differentiation GO:0045444 50 27 0,000 0,14872722 0,17584162 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14872722 0,17575525 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14872722 0,17566897 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14872722 0,17558277 ! autophagy GO:0006914 41 27 0,000 0,14872722 0,17549666 ! male gonad development GO:0008584 44 27 0,000 0,14872722 0,17541063 ! response to toxin GO:0009636 47 27 0,000 0,14872722 0,17532469 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14872722 0,17523883 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14872722 0,17515305 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14872722 0,17506736 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14872722 0,17498176 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14872722 0,17489623 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15379129 0,18076299 ! circadian rhythm GO:0007623 50 28 0,000 0,15379129 0,18067473 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15379129 0,18058655 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15379129 0,18049846 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15379129 0,18041045 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15379129 0,18032253 ! synaptogenesis GO:0007416 42 28 0,000 0,15379129 0,1802347 ! lipid oxidation GO:0034440 43 28 0,000 0,15379129 0,18014695 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15379129 0,18005929 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15379129 0,17997171 ! translational initiation GO:0006413 65 29 0,000 0,1588254 0,18577244 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,1588254 0,18568217 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1588254 0,18559199 ! regulation of pH GO:0006885 43 29 0,000 0,1588254 0,1855019 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1588254 0,18541189 ! catechol metabolic process GO:0009712 54 29 0,000 0,1588254 0,18532197 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,1588254 0,18523214 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,1588254 0,1851424 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1588254 0,18505274 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1588254 0,18496317 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1588254 0,18487369 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,1588254 0,18478429 ! cell fate determination GO:0001709 60 29 0,000 0,1588254 0,18469498 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1588254 0,18460575 ! detection of light stimulus GO:0009583 38 29 0,000 0,1588254 0,18451662 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,1588254 0,18442756 ! regulation of coagulation GO:0050818 46 29 0,000 0,1588254 0,1843386 ! phenol metabolic process GO:0018958 55 30 0,000 0,16382973 0,19005512 ! zinc ion transport GO:0006829 45 30 0,000 0,16382973 0,18996353 ! membrane docking GO:0022406 61 30 0,000 0,16382973 0,18987203 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16382973 0,18978061 ! cell junction assembly GO:0034329 78 30 0,000 0,16382973 0,18968928 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16382973 0,18959804 ! acute-phase response GO:0006953 49 30 0,000 0,16382973 0,18950689 ! myofibril assembly GO:0030239 47 30 0,000 0,16382973 0,18941582 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16382973 0,18932484 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,16382973 0,18923395 ! phospholipid transport GO:0015914 51 30 0,000 0,16382973 0,18914315 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16382973 0,18905243 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16382973 0,18896181 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16880445 0,19460638 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16880445 0,19451317 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16880445 0,19442006 ! collagen metabolic process GO:0032963 45 31 0,000 0,16880445 0,19432704 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16880445 0,1942341 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16880445 0,19414126 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16880445 0,1940485 ! ovulation cycle process GO:0022602 49 31 0,000 0,16880445 0,19395583 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16880445 0,19386325 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16880445 0,19377076 ! peptide transport GO:0015833 55 31 0,000 0,16880445 0,19367835 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16880445 0,19358604 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16880445 0,19349381 ! mesoderm formation GO:0001707 69 31 0,000 0,16880445 0,19340167 ! natural killer cell activation GO:0030101 45 31 0,000 0,16880445 0,19330962 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16880445 0,19321765 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16880445 0,19312578 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16880445 0,19303399 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17374974 0,19859472 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17374974 0,19850042 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17374974 0,19840621 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17374974 0,19831209 ! cholesterol transport GO:0030301 56 32 0,000 0,17374974 0,19821805 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17374974 0,19812411 ! spliceosome assembly GO:0000245 67 32 0,000 0,17374974 0,19803026 ! spindle organization GO:0007051 46 32 0,000 0,17374974 0,19793649 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17374974 0,19784282 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17374974 0,19774923 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17374974 0,19765573 ! muscle cell development GO:0055001 49 32 0,000 0,17374974 0,19756232 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17374974 0,197469 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17374974 0,19737577 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17374974 0,19728262 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,17374974 0,19718956 ! ovulation cycle GO:0042698 51 32 0,000 0,17374974 0,19709659 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17374974 0,19700371 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17374974 0,19691092 ! gene silencing GO:0016458 65 32 0,000 0,17374974 0,19681821 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17866577 0,20229169 ! post-embryonic development GO:0009791 69 33 0,000 0,17866577 0,20219654 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,17866577 0,20210148 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17866577 0,20200651 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17866577 0,20191162 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17866577 0,20181683 ! sterol transport GO:0015918 57 33 0,000 0,17866577 0,20172212 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17866577 0,20162751 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17866577 0,20153298 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17866577 0,20143854 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18355272 0,20685145 ! glial cell differentiation GO:0010001 63 34 0,000 0,18355272 0,2067546 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18355272 0,20665785 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18355272 0,2065612 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,18355272 0,20646463 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18355272 0,20636815 ! mismatch repair GO:0006298 46 34 0,000 0,18355272 0,20627176 ! spermatid development GO:0007286 63 34 0,000 0,18355272 0,20617546 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18355272 0,20607925 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18355272 0,20598313 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,18841074 0,21133625 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18841074 0,21123777 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18841074 0,21113938 ! female gonad development GO:0008585 58 35 0,000 0,18841074 0,21104109 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18841074 0,21094288 GO:0006639|acylglycerol metabolic process, ! vesicle localization GO:0051648 64 35 0,000 0,18841074 0,21084477 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,19324003 0,21614854 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,19324003 0,2160481 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19324003 0,21594775 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19324003 0,2158475 ! cell junction organization GO:0034330 86 36 0,000 0,19324003 0,21574733 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19324003 0,21564727 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,19324003 0,21554729 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19324003 0,21544741 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19324003 0,21534762 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19324003 0,21524792 ! aerobic respiration GO:0009060 55 36 0,000 0,19324003 0,21514831 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19324003 0,2150488 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19804073 0,22028941 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19804073 0,22018762 ! meiosis I GO:0007127 65 37 0,000 0,19804073 0,22008591 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19804073 0,2199843 ! sister chromatid segregation GO:0000819 58 37 0,000 0,19804073 0,21988279 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19804073 0,21978137 ! organic anion transport GO:0015711 68 37 0,000 0,19804073 0,21968004 ! tissue remodeling GO:0048771 76 37 0,000 0,19804073 0,2195788 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19804073 0,21947766 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19804073 0,21937661 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19804073 0,21927566 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19804073 0,21917479 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,19804073 0,21907402 ! spermatid differentiation GO:0048515 66 37 0,000 0,19804073 0,21897335 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20281303 0,22414706 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20281303 0,22404415 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20281303 0,22394133 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20281303 0,2238386 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,20281303 0,22373597 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20281303 0,22363343 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,20281303 0,22353099 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20281303 0,22342864 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20281303 0,22332639 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20281303 0,22322422 ! mRNA catabolic process GO:0006402 71 39 0,000 0,20755709 0,22834127 ! learning GO:0007612 77 39 0,000 0,20755709 0,22823691 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20755709 0,22813264 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,20755709 0,22802847 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20755709 0,2279244 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20755709 0,22782042 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20755709 0,22771653 ! RNA modification GO:0009451 57 39 0,000 0,20755709 0,22761274 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20755709 0,22750904 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21227307 0,2325724 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21227307 0,23246655 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21227307 0,23236078 ! feeding behavior GO:0007631 59 40 0,000 0,21227307 0,23225512 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,21227307 0,23214955 ! mesenchymal cell development GO:0014031 87 40 0,000 0,21227307 0,23204407 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 0,000 0,21227307 0,23193869 ! cytokinesis GO:0000910 72 40 0,000 0,21227307 0,23183341 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21696114 0,23684596 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21696114 0,23673855 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21696114 0,23663123 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21696114 0,23652401 ! gliogenesis GO:0042063 88 41 0,000 0,21696114 0,23641689 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21696114 0,23630987 ! female gamete generation GO:0007292 61 41 0,000 0,21696114 0,23620294 ! polyol metabolic process GO:0019751 66 41 0,000 0,21696114 0,23609611 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22162146 0,24105843 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,22162146 0,2409495 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22162146 0,24084067 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22162146 0,24073194 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22162146 0,24062331 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,22162146 0,24051477 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,22625421 0,24543175 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22625421 0,24532115 ! glucose transport GO:0015758 65 43 0,000 0,22625421 0,24521064 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22625421 0,24510024 ! striated muscle contraction GO:0006941 77 43 0,000 0,22625421 0,24498993 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22625421 0,24487972 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23085953 0,24975181 ! hexose transport GO:0008645 67 44 0,000 0,23085953 0,24963957 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23085953 0,24952742 ! male sex differentiation GO:0046661 76 44 0,000 0,23085953 0,24941537 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23085953 0,24930343 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23085953 0,24919158 ! maintenance of location in cell GO:0051651 97 44 0,000 0,23085953 0,24907984 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,2354376 0,25390536 ! glycolysis GO:0006096 65 45 0,000 0,2354376 0,2537916 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,2354376 0,25367795 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,2354376 0,25356439 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,2354376 0,25345094 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2354376 0,25333759 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23998856 0,25811913 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,23998856 0,25800379 ! response to calcium ion GO:0051592 81 47 0,000 0,24451259 0,26275002 ! endosome transport GO:0016197 108 47 0,000 0,24451259 0,26263272 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24451259 0,26251553 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24451259 0,26239844 ! JNK cascade GO:0007254 91 47 0,000 0,24451259 0,26228145 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24451259 0,26216457 ! protein homooligomerization GO:0051260 76 47 0,000 0,24451259 0,26204779 ! mitochondrial transport GO:0006839 82 48 0,000 0,24900984 0,26674874 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24900984 0,26663003 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24900984 0,26651142 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24900984 0,26639292 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24900984 0,26627452 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25348046 0,27093469 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25348046 0,27081439 ! regulation of ion transport GO:0043269 77 49 0,000 0,25348046 0,27069418 ! peptide metabolic process GO:0006518 76 49 0,000 0,25348046 0,27057409 ! endocrine system development GO:0035270 104 49 0,000 0,25348046 0,2704541 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25348046 0,27033422 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25348046 0,27021444 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25348046 0,27009477 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25792462 0,27470856 ! neuromuscular process GO:0050905 99 50 0,000 0,25792462 0,27458701 ! regulation of ossification GO:0030278 117 50 0,000 0,25792462 0,27446557 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25792462 0,27434423 ! viral infectious cycle GO:0019058 99 51 0,000 0,26234247 0,27892001 ! excretion GO:0007588 83 51 0,000 0,26234247 0,27879682 ! chromatin remodeling GO:0006338 109 51 0,000 0,26234247 0,27867373 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,26234247 0,27855075 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,26234247 0,27842788 ! vesicle organization GO:0016050 107 51 0,000 0,26234247 0,27830511 ! regulation of cell shape GO:0008360 125 51 0,000 0,26234247 0,27818246 ! membrane fusion GO:0006944 110 52 0,000 0,26673417 0,28271472 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,27109986 0,28721544 ! RNA catabolic process GO:0006401 93 53 0,000 0,27109986 0,28708903 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,27109986 0,28696272 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,27109986 0,28683653 ! cell maturation GO:0048469 100 53 0,000 0,27109986 0,28671045 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,27109986 0,28658448 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27109986 0,28645862 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27543971 0,29091657 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27543971 0,29078892 ! chloride transport GO:0006821 90 55 0,000 0,27975386 0,29521394 ! glucose catabolic process GO:0006007 82 55 0,000 0,27975386 0,29508452 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27975386 0,29495521 ! gastrulation GO:0007369 112 55 0,000 0,27975386 0,29482601 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,27975386 0,29469693 ! nuclear export GO:0051168 97 55 0,000 0,27975386 0,29456796 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,27975386 0,2944391 ! regulation of actin filament length GO:0030832 105 56 0,000 0,28404246 0,29882211 ! sensory perception of smell GO:0007608 80 56 0,000 0,28404246 0,29869151 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28404246 0,29856102 ! proton transport GO:0015992 94 56 0,000 0,28404246 0,29843064 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,28404246 0,29830038 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,28830568 0,30264549 ! maintenance of location GO:0051235 118 57 0,000 0,28830568 0,3025135 ! hydrogen transport GO:0006818 97 58 0,000 0,29254364 0,30682651 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,29254364 0,30669281 ! regulation of endocytosis GO:0030100 91 58 0,000 0,29254364 0,30655924 ! adult behavior GO:0030534 99 58 0,000 0,29254364 0,30642577 ! positive regulation of secretion GO:0051047 95 59 0,000 0,29675651 0,31070329 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29675651 0,31056815 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29675651 0,31043312 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,29675651 0,31029821 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,30094444 0,31454054 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,30094444 0,31440396 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30510756 0,31861492 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,30510756 0,3184767 ! mesoderm development GO:0007498 119 61 0,000 0,30510756 0,31833859 ! tRNA processing GO:0008033 89 61 0,000 0,30510756 0,3182006 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30510756 0,31806273 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30924602 0,3222373 ! gonad development GO:0008406 98 62 0,000 0,30924602 0,32209781 ! regulation of mitosis GO:0007088 105 63 0,000 0,31335998 0,3262415 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,31335998 0,3261004 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,31335998 0,32595941 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31744957 0,33007073 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31744957 0,32992815 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31744957 0,3297857 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31744957 0,32964336 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31744957 0,32950115 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32151494 0,33357695 ! germ cell development GO:0007281 118 65 0,000 0,32151494 0,33343317 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32151494 0,33328951 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,32555623 0,33733346 ! actin filament organization GO:0007015 148 66 0,000 0,32555623 0,33718824 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32555623 0,33704315 ! secondary metabolic process GO:0019748 116 66 0,000 0,32555623 0,33689819 ! developmental maturation GO:0021700 116 66 0,000 0,32555623 0,33675335 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,32957358 0,34076237 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,32957358 0,340616 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,32957358 0,34046975 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,32957358 0,34032362 ! hexose catabolic process GO:0019320 104 67 0,000 0,32957358 0,34017762 ! activation of immune response GO:0002253 105 67 0,000 0,32957358 0,34003175 ! amino acid transport GO:0006865 125 68 0,000 0,33356714 0,34400451 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33356714 0,34385713 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,33356714 0,34370986 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,33753704 0,34765159 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33753704 0,34750283 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33753704 0,34735419 ! amine catabolic process GO:0009310 117 71 0,000 0,34540642 0,35530049 ! reproductive structure development GO:0048608 113 71 0,000 0,34540642 0,35514865 ! humoral immune response GO:0006959 109 71 0,000 0,34540642 0,35499694 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,34540642 0,35484537 ! regulation of immune effector process GO:0002697 137 71 0,000 0,34540642 0,35469392 ! acute inflammatory response GO:0002526 113 72 0,000 0,34930618 0,35854551 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,34930618 0,35839261 ! carbohydrate transport GO:0008643 110 72 0,000 0,34930618 0,35823984 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,35318284 0,36206132 ! fertilization GO:0009566 90 73 0,000 0,35318284 0,36190712 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,35703653 0,36570025 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,35703653 0,36554463 ! organelle localization GO:0051640 136 74 0,000 0,35703653 0,36538915 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,36086739 0,36915261 ! rhythmic process GO:0048511 128 75 0,000 0,36086739 0,36899572 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,36467555 0,37273125 ! defense response to bacterium GO:0042742 89 76 0,000 0,36467555 0,37257298 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,36467555 0,37241484 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,36467555 0,37225684 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36846114 0,37596162 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,36846114 0,37580225 ! blood coagulation GO:0007596 146 78 0,000 0,37222431 0,37947953 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,37596517 0,38313096 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37596517 0,38296876 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,37596517 0,38280669 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,37968387 0,38642952 ! muscle cell differentiation GO:0042692 159 80 0,000 0,37968387 0,38626613 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37968387 0,38610287 ! inorganic anion transport GO:0015698 138 80 0,000 0,37968387 0,38593975 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,38705528 0,39326647 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,38705528 0,39310047 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,38705528 0,3929346 ! regulation of lyase activity GO:0051339 160 83 0,000 0,39070826 0,39647578 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,39433958 0,39999201 ! hemostasis GO:0007599 158 84 0,000 0,39433958 0,39982345 ! nucleosome assembly GO:0006334 122 85 0,000 0,39794939 0,40331349 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,40153779 0,40677892 ! chromatin assembly GO:0031497 124 86 0,000 0,40153779 0,40660772 ! alcohol catabolic process GO:0046164 130 86 0,000 0,40153779 0,40643666 ! amine transport GO:0015837 155 86 0,000 0,40153779 0,40626574 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,40510493 0,40970259 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,40865093 0,41311518 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,40865093 0,41294168 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,40865093 0,41276832 ! cellular defense response GO:0006968 114 89 0,000 0,4121759 0,4161541 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,4121759 0,41597954 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,41567998 0,41934006 ! sex differentiation GO:0007548 145 90 0,000 0,41567998 0,41916431 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41567998 0,41898871 ! sterol metabolic process GO:0016125 152 91 0,000 0,41916329 0,42232281 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41916329 0,42214603 ! nucleosome organization GO:0034728 138 92 0,000 0,42262595 0,42545524 ! vitamin metabolic process GO:0006766 139 92 0,000 0,42262595 0,4252773 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,42606808 0,42856179 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,42606808 0,4283827 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,42606808 0,42820376 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,4294898 0,43146241 ! female pregnancy GO:0007565 164 94 0,000 0,4294898 0,43128233 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,43289124 0,43451661 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,43627251 0,43772796 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,43627251 0,4375455 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,43963373 0,44073281 ! hormone metabolic process GO:0042445 157 97 0,000 0,43963373 0,44054925 ! response to virus GO:0009615 160 98 0,000 0,44297502 0,4437127 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,44297502 0,44352805 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,44297502 0,44334355 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,4462965 0,44648207 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,4462965 0,4462965