pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6313-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! DNA synthesis during DNA repair GO:0000731 5 5 2,000 3,157E-06 5,818E-03 ! regulation of cell growth GO:0001558 97 96 6,000 3,813E-06 3,514E-03 ! regulation of cell size GO:0008361 68 68 5,000 6,598E-06 4,054E-03 ! negative regulation of cell growth GO:0030308 32 32 3,000 6,499E-05 0,02994261 ! negative regulation of cell size GO:0045792 33 33 3,000 7,357E-05 0,02711894 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 2,000 8,68E-05 0,0266634 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 1,163E-04 0,03063091 ! negative regulation of growth GO:0045926 37 37 3,000 1,163E-04 0,02680205 ! negative regulation of kinase activity GO:0033673 38 38 3,000 1,294E-04 0,026491 ! negative regulation of transferase activity GO:0051348 40 40 3,000 1,585E-04 0,02921812 ! triglyceride metabolic process GO:0006641 16 16 2,000 1,675E-04 0,02806089 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 2,417E-04 0,03711541 ! neutral lipid metabolic process GO:0006638 18 18 2,000 2,417E-04 0,03426038 GO:0006639|acylglycerol metabolic process, ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 2,856E-04 0,03759339 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 3,046E-04 0,03742761 ! organic ether metabolic process GO:0018904 20 20 2,000 3,343E-04 0,03850981 GO:0006662|glycerol ether metabolic process, ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 3,343E-04 0,03624453 ! positive regulation of transferase activity GO:0051347 91 88 4,000 3,391E-04 0,03472119 GO:0033674|positive regulation of kinase activity, ! cell cycle arrest GO:0007050 49 49 3,000 3,51E-04 0,03404878 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 3,51E-04 0,03234634 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 3,881E-04 0,03406357 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 3,881E-04 0,03251523 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 4,098E-04 0,03283783 GO:0051325|interphase, ! sister chromatid segregation GO:0000819 22 22 2,000 4,472E-04 0,03434306 ! spindle organization GO:0007051 22 22 2,000 4,472E-04 0,03296934 ! cytokinesis GO:0000910 23 22 2,000 4,472E-04 0,03170129 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 1,000 4,703E-04 0,03210461 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! prostate gland development GO:0030850 5 5 1,000 4,703E-04 0,03095802 ! tyrosine metabolic process GO:0006570 5 5 1,000 4,703E-04 0,0298905 ! maintenance of protein location in nucleus GO:0051457 5 5 1,000 4,703E-04 0,02889415 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 4,703E-04 0,02796208 ! decidualization GO:0046697 5 5 1,000 4,703E-04 0,02708827 ! intracellular cholesterol transport GO:0032367 5 5 1,000 4,703E-04 0,02626741 GO:0032366|intracellular sterol transport, ! male genitalia development GO:0030539 5 5 1,000 4,703E-04 0,02549484 ! quaternary ammonium group transport GO:0015697 5 5 1,000 4,703E-04 0,02476642 ! blastocyst formation GO:0001825 5 5 1,000 4,703E-04 0,02407846 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 5,82E-04 0,02899234 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 7,024E-04 0,03406441 ! positive regulation of cell growth GO:0030307 6 6 1,000 7,024E-04 0,03319096 ! oligodendrocyte differentiation GO:0048709 6 6 1,000 7,024E-04 0,03236118 ! L-phenylalanine metabolic process GO:0006558 6 6 1,000 7,024E-04 0,03157189 GO:0006559|L-phenylalanine catabolic process, ! focal adhesion formation GO:0048041 7 6 1,000 7,024E-04 0,03082018 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 7,024E-04 0,03010343 GO:0070667|negative regulation of mast cell proliferation, ! phagocytosis, engulfment GO:0006911 6 6 1,000 7,024E-04 0,02941926 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 7,024E-04 0,0287655 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,024E-04 0,02814016 ! genitalia development GO:0048806 6 6 1,000 7,024E-04 0,02754143 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 7,024E-04 0,02696765 ! organic cation transport GO:0015695 6 6 1,000 7,024E-04 0,02641729 ! maternal placenta development GO:0001893 6 6 1,000 7,024E-04 0,02588895 ! regulation of embryonic development GO:0045995 6 6 1,000 7,024E-04 0,02538132 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 7,404E-04 0,02624166 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 9,238E-04 0,03212463 ! keratinocyte proliferation GO:0043616 7 7 1,000 9,789E-04 0,03341039 ! regulation of mRNA processing GO:0050684 7 7 1,000 9,789E-04 0,03280292 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 9,789E-04 0,03221716 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! intracellular lipid transport GO:0032365 7 7 1,000 9,789E-04 0,03165195 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 9,789E-04 0,03110622 ! negative regulation of T cell activation GO:0050868 7 7 1,000 9,789E-04 0,030579 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,095E-03 0,03362811 ! response to radiation GO:0009314 70 68 3,000 1,225E-03 0,0369963 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 1,293E-03 0,03844307 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,299E-03 0,03801344 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,299E-03 0,03741948 ! cofactor transport GO:0051181 8 8 1,000 1,299E-03 0,03684379 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,299E-03 0,03628555 ! regulation of cell migration GO:0030334 71 71 3,000 1,439E-03 0,03957722 ! secretion by cell GO:0032940 75 72 3,000 1,516E-03 0,04107915 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,639E-03 0,04376939 ! positive regulation of cell size GO:0045793 9 9 1,000 1,663E-03 0,04379139 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,663E-03 0,04317461 ! phospholipid efflux GO:0033700 9 9 1,000 1,663E-03 0,04257496 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,663E-03 0,04199174 ! pigmentation during development GO:0048066 9 9 1,000 1,663E-03 0,04142429 ! reverse cholesterol transport GO:0043691 9 9 1,000 1,663E-03 0,04087196 ! negative regulation of caspase activity GO:0043154 9 9 1,000 1,663E-03 0,04033417 ! peptide secretion GO:0002790 9 9 1,000 1,663E-03 0,03981035 ! aromatic amino acid family catabolic process GO:0009074 9 9 1,000 1,663E-03 0,03929996 ! cholesterol efflux GO:0033344 9 9 1,000 1,663E-03 0,0388025 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,784E-03 0,04108901 ! regulation of mitosis GO:0007088 37 36 2,000 1,936E-03 0,04405526 GO:0051783|regulation of nuclear division, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,07E-03 0,04652093 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,07E-03 0,04596044 ! cell-substrate junction assembly GO:0007044 11 10 1,000 2,07E-03 0,04541329 ! neuromuscular junction development GO:0007528 10 10 1,000 2,07E-03 0,04487901 ! mismatch repair GO:0006298 10 10 1,000 2,07E-03 0,04435716 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 2,097E-03 0,04441865 ! regulation of locomotion GO:0040012 79 79 3,000 2,136E-03 0,04473529 ! regulation of cell motion GO:0051270 79 79 3,000 2,136E-03 0,04423265 ! exocytosis GO:0006887 40 38 2,000 2,265E-03 0,04639136 ! chromosome segregation GO:0007059 38 38 2,000 2,265E-03 0,04588157 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 2,265E-03 0,04538286 ! nucleotide-excision repair GO:0006289 40 39 2,000 2,442E-03 0,04839927 ! protein secretion GO:0009306 11 11 1,000 2,519E-03 0,04937998 ! skin development GO:0043588 11 11 1,000 2,519E-03 0,04886019 ! activation of MAPKK activity GO:0000186 12 11 1,000 2,519E-03 0,04835123 ! body fluid secretion GO:0007589 11 11 1,000 2,519E-03 0,04785276 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,519E-03 0,04736447 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 2,519E-03 0,04688604 ! vitamin transport GO:0051180 11 11 1,000 2,519E-03 0,04641718 ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 2,519E-03 0,04595761 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,519E-03 0,04550704 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 2,627E-03 0,04701357 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,821E-03 0,04999291 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 3,009E-03 0,05281265 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 3,009E-03 0,05231442 ! regulation of chromosome organization GO:0033044 12 12 1,000 3,009E-03 0,0518255 ! G1 phase GO:0051318 13 12 1,000 3,009E-03 0,05134563 ! neurotransmitter secretion GO:0007269 14 12 1,000 3,009E-03 0,05087457 ! aromatic compound catabolic process GO:0019439 13 12 1,000 3,009E-03 0,05041208 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 3,009E-03 0,04995791 ! negative regulation of translation GO:0017148 12 12 1,000 3,009E-03 0,04951186 ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,54E-03 0,05773878 ! vasculogenesis GO:0001570 13 13 1,000 3,54E-03 0,0572323 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,54E-03 0,05673463 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 3,54E-03 0,05624554 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 3,54E-03 0,05576481 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,54E-03 0,05529222 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,54E-03 0,05482758 ! response to cytokine stimulus GO:0034097 13 13 1,000 3,54E-03 0,05437069 ! activation of JUN kinase activity GO:0007257 13 13 1,000 3,54E-03 0,05392134 ! blastocyst development GO:0001824 13 13 1,000 3,54E-03 0,05347936 ! tissue homeostasis GO:0001894 13 13 1,000 3,54E-03 0,05304457 GO:0048871|multicellular organismal homeostasis, ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 3,683E-03 0,05473614 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 4,112E-03 0,06062502 ! lysosome organization GO:0007040 14 14 1,000 4,112E-03 0,06014387 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 4,112E-03 0,05967029 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 1,000 4,112E-03 0,05920412 ! base-excision repair GO:0006284 14 14 1,000 4,112E-03 0,05874517 ! response to organic cyclic substance GO:0014070 15 14 1,000 4,112E-03 0,05829329 ! sex differentiation GO:0007548 47 47 2,000 4,167E-03 0,05863091 ! regulation of cell cycle process GO:0010564 50 48 2,000 4,424E-03 0,06176425 ! protein localization in nucleus GO:0034504 48 48 2,000 4,424E-03 0,06129986 ! gland development GO:0048732 51 49 2,000 4,689E-03 0,06449552 ! cellular lipid catabolic process GO:0044242 50 49 2,000 4,689E-03 0,06401778 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 4,723E-03 0,06400897 ! striated muscle cell differentiation GO:0051146 16 15 1,000 4,723E-03 0,06354175 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 4,723E-03 0,0630813 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 4,723E-03 0,06262748 ! response to ionizing radiation GO:0010212 16 15 1,000 4,723E-03 0,06218014 ! phospholipid transport GO:0015914 15 15 1,000 4,723E-03 0,06173914 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 4,723E-03 0,06130436 ! negative regulation of cell activation GO:0050866 15 15 1,000 4,723E-03 0,06087566 ! response to hormone stimulus GO:0009725 102 100 3,000 5,01E-03 0,06412107 ! positive regulation of mitosis GO:0045840 16 16 1,000 5,374E-03 0,06830846 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 5,374E-03 0,06784059 ! vacuole organization GO:0007033 16 16 1,000 5,374E-03 0,06737909 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 5,374E-03 0,06692383 ! positive regulation of catabolic process GO:0009896 16 16 1,000 5,374E-03 0,06647467 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 5,374E-03 0,06603151 GO:0043507|positive regulation of JUN kinase activity, ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 6,064E-03 0,07401077 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 6,064E-03 0,07352386 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 6,064E-03 0,07304331 ! myelination GO:0042552 17 17 1,000 6,064E-03 0,072569 ! glucose transport GO:0015758 17 17 1,000 6,064E-03 0,07210081 ! cell junction assembly GO:0034329 18 17 1,000 6,064E-03 0,07163863 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 6,064E-03 0,07118233 ! pigmentation GO:0043473 17 17 1,000 6,064E-03 0,07073181 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 6,485E-03 0,07517182 ! regulation of cell adhesion GO:0030155 56 55 2,000 6,485E-03 0,074702 ! meiosis I GO:0007127 18 18 1,000 6,792E-03 0,07774476 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 6,792E-03 0,07726485 ! hexose transport GO:0008645 18 18 1,000 6,792E-03 0,07679083 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 1,000 6,792E-03 0,0763226 GO:0055092|sterol homeostasis, ! ensheathment of neurons GO:0007272 18 18 1,000 6,792E-03 0,07586004 GO:0008366|axon ensheathment, ! reproductive developmental process GO:0003006 56 56 2,000 6,819E-03 0,07570853 ! extracellular structure organization GO:0043062 56 56 2,000 6,819E-03 0,07525519 ! DNA damage checkpoint GO:0000077 19 19 1,000 7,557E-03 0,08290217 ! glial cell differentiation GO:0010001 19 19 1,000 7,557E-03 0,08241163 ! peripheral nervous system development GO:0007422 19 19 1,000 7,557E-03 0,08192685 ! placenta development GO:0001890 19 19 1,000 7,557E-03 0,08144775 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 7,881E-03 0,08445078 ! protein localization in organelle GO:0033365 59 59 2,000 7,881E-03 0,08396262 ! nucleus organization GO:0006997 20 20 1,000 8,36E-03 0,08854374 ! phagocytosis GO:0006909 21 20 1,000 8,36E-03 0,08803777 ! lipid oxidation GO:0034440 20 20 1,000 8,36E-03 0,08753756 GO:0019395|fatty acid oxidation, ! carboxylic acid catabolic process GO:0046395 63 61 2,000 8,641E-03 0,08997438 GO:0016054|organic acid catabolic process, ! mammary gland development GO:0030879 23 21 1,000 9,199E-03 0,09524191 ! protein amino acid lipidation GO:0006497 21 21 1,000 9,199E-03 0,09470983 ! cholesterol transport GO:0030301 21 21 1,000 9,199E-03 0,09418367 GO:0015918|sterol transport, ! DNA integrity checkpoint GO:0031570 21 21 1,000 9,199E-03 0,09366332 ! regulation of action potential in neuron GO:0019228 21 21 1,000 9,199E-03 0,09314868 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 9,199E-03 0,09263967 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 9,199E-03 0,0921362 ! negative regulation of protein transport GO:0051224 21 21 1,000 9,199E-03 0,09163816 ! glycerolipid metabolic process GO:0046486 65 64 2,000 9,859E-03 0,09768658 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01007376 0,09928312 ! odontogenesis GO:0042476 22 22 1,000 0,01007376 0,09875501 ! cell junction organization GO:0034330 23 22 1,000 0,01007376 0,0982325 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01007376 0,09771549 ! erythrocyte differentiation GO:0030218 23 22 1,000 0,01007376 0,09720389 ! male sex differentiation GO:0046661 22 22 1,000 0,01007376 0,09669762 ! fatty acid catabolic process GO:0009062 23 22 1,000 0,01007376 0,09619659 ! cytokine production GO:0001816 22 22 1,000 0,01007376 0,09570074 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01098443 0,1038169 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 0,01098443 0,10328722 ! positive regulation of growth GO:0045927 23 23 1,000 0,01098443 0,10276292 ! lipid homeostasis GO:0055088 23 23 1,000 0,01098443 0,10224392 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,01098443 0,10173013 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,01098443 0,10122148 ! striated muscle tissue development GO:0014706 69 67 2,000 0,01117181 0,10243609 ! regulation of action potential GO:0001508 24 24 1,000 0,0119301 0,10884736 ! gliogenesis GO:0042063 24 24 1,000 0,0119301 0,10831117 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,0119301 0,10778023 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,0119301 0,10725447 ! maintenance of protein location GO:0045185 25 24 1,000 0,0119301 0,10673382 ! muscle tissue development GO:0060537 72 70 2,000 0,01258154 0,11201823 ! endosome transport GO:0016197 25 25 1,000 0,01291026 0,11439237 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01291026 0,11384503 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01291026 0,11330292 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01291026 0,11276594 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01291026 0,11223402 ! translational elongation GO:0006414 71 71 2,000 0,01307313 0,11311633 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01392442 0,11991916 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01392442 0,11936139 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01392442 0,11880879 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01392442 0,11826129 ! synapse organization GO:0050808 26 26 1,000 0,01392442 0,1177188 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01497206 0,12599774 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,01497206 0,12542502 ! cell growth GO:0016049 27 27 1,000 0,01497206 0,12485748 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,01605269 0,13326627 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 1,000 0,01605269 0,13266866 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01605269 0,13207639 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01605269 0,13148939 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01716583 0,13998503 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,01716583 0,13936836 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01716583 0,13875709 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01716583 0,13815117 ! response to UV GO:0009411 29 29 1,000 0,01716583 0,13755051 ! water-soluble vitamin metabolic process GO:0006767 30 30 1,000 0,01831097 0,14609144 ! vesicle organization GO:0016050 30 30 1,000 0,01831097 0,14546174 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01831097 0,14483744 ! MAPKKK cascade GO:0000165 82 81 2,000 0,01859387 0,14644661 ! lipid catabolic process GO:0016042 82 81 2,000 0,01859387 0,14582344 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01948765 0,15218536 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,01948765 0,15154323 ! regulation of DNA replication GO:0006275 32 31 1,000 0,01948765 0,15090649 ! extracellular matrix organization GO:0030198 31 31 1,000 0,01948765 0,15027508 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01948765 0,14964894 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01948765 0,14902799 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01948765 0,14841217 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01948765 0,14780142 ! muscle fiber development GO:0048747 32 32 1,000 0,02069539 0,15631805 ! lipid modification GO:0030258 32 32 1,000 0,02069539 0,15568001 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02069539 0,15504717 ! maintenance of location GO:0051235 33 32 1,000 0,02069539 0,15441945 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,02111333 0,15690268 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,02177116 0,16114156 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02193371 0,16169532 ! amino acid transport GO:0006865 33 33 1,000 0,02193371 0,16105111 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02193371 0,16041202 ! response to metal ion GO:0010038 34 34 1,000 0,02320215 0,16901804 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02320215 0,16835261 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,02320215 0,16769241 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02320215 0,16703736 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02320215 0,16638741 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,02450025 0,17501532 GO:0048609|reproductive process in a multicellular organism, ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02450025 0,17433959 ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,0252284 0,17883056 ! DNA replication GO:0006260 91 91 2,000 0,0252284 0,17814539 ! response to inorganic substance GO:0010035 36 36 1,000 0,02582754 0,18167999 ! positive regulation of cell migration GO:0030335 36 36 1,000 0,02582754 0,1809892 ! female pregnancy GO:0007565 37 36 1,000 0,02582754 0,18030363 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02582754 0,17962324 ! meiosis GO:0007126 37 37 1,000 0,02718358 0,1883434 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 1,000 0,02718358 0,18763799 ! lung development GO:0030324 38 37 1,000 0,02718358 0,18693785 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,02718358 0,18624291 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02718358 0,18555312 ! blood vessel development GO:0001568 95 94 2,000 0,02743719 0,18659317 ! neurotransmitter transport GO:0006836 40 38 1,000 0,02856792 0,19356869 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02856792 0,19285965 ! urogenital system development GO:0001655 38 38 1,000 0,02856792 0,19215578 ! meiotic cell cycle GO:0051321 38 38 1,000 0,02856792 0,19145703 ! axon guidance GO:0007411 39 38 1,000 0,02856792 0,19076335 ! vasculature development GO:0001944 97 96 2,000 0,02896566 0,19272095 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02998012 0,1987531 ! activation of MAPK activity GO:0000187 39 39 1,000 0,02998012 0,19804072 ! respiratory tube development GO:0030323 40 39 1,000 0,02998012 0,19733343 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02998012 0,19663118 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,02998012 0,19593391 ! respiratory system development GO:0060541 40 39 1,000 0,02998012 0,19524156 ! positive regulation of cell motion GO:0051272 39 39 1,000 0,02998012 0,19455409 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,03141973 0,20318095 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,03141973 0,20247053 ! organelle localization GO:0051640 41 40 1,000 0,03141973 0,20176505 ! muscle organ development GO:0007517 102 100 2,000 0,03215644 0,20577886 ! hemopoiesis GO:0030097 104 100 2,000 0,03215644 0,20506683 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03288633 0,20899831 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 1,000 0,03288633 0,2082801 ! regulation of caspase activity GO:0043281 41 41 1,000 0,03288633 0,20756681 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03437948 0,21625047 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03437948 0,21551492 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,03437948 0,21478436 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,03437948 0,21405874 ! protein ubiquitination GO:0016567 43 42 1,000 0,03437948 0,213338 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,03437948 0,2126221 ! rRNA transcription GO:0009303 5 5 0,000 0,03441022 0,21210045 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03441022 0,21139345 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03441022 0,21069115 ! neuron fate specification GO:0048665 5 5 0,000 0,03441022 0,2099935 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03441022 0,20930045 ! reproductive cellular process GO:0048610 5 5 0,000 0,03441022 0,20861196 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03441022 0,20792799 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03441022 0,20724848 ! metencephalon development GO:0022037 5 5 0,000 0,03441022 0,20657341 ! water transport GO:0006833 5 5 0,000 0,03441022 0,20590271 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03441022 0,20523636 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03441022 0,20457431 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03441022 0,20391651 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03441022 0,20326294 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03441022 0,20261353 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03441022 0,20196827 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03441022 0,2013271 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03441022 0,20068999 ! filopodium assembly GO:0046847 7 5 0,000 0,03441022 0,2000569 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03441022 0,19942779 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03441022 0,19880262 ! GTP metabolic process GO:0046039 5 5 0,000 0,03441022 0,19818136 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03441022 0,19756397 ! mRNA stabilization GO:0048255 5 5 0,000 0,03441022 0,19695042 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03441022 0,19634067 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03441022 0,19573468 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03441022 0,19513242 ! social behavior GO:0035176 5 5 0,000 0,03441022 0,19453385 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03441022 0,19393895 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03441022 0,19334767 ! memory GO:0007613 5 5 0,000 0,03441022 0,19275999 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03441022 0,19217587 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03441022 0,19159527 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03441022 0,19101818 ! response to lipid GO:0033993 5 5 0,000 0,03441022 0,19044455 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03441022 0,18987436 ! hippocampus development GO:0021766 6 5 0,000 0,03441022 0,18930757 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03441022 0,18874415 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03441022 0,18818408 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03441022 0,18762733 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03441022 0,18707385 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03441022 0,18652364 ! heart looping GO:0001947 5 5 0,000 0,03441022 0,18597665 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03441022 0,18543285 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03441022 0,18489223 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03441022 0,18435476 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03441022 0,18382039 ! pH reduction GO:0045851 5 5 0,000 0,03441022 0,18328912 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03441022 0,18276091 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03441022 0,18223574 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03441022 0,18171357 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03441022 0,18119439 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03441022 0,18067817 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03441022 0,18016487 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03441022 0,17965449 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03441022 0,17914699 ! adrenal gland development GO:0030325 5 5 0,000 0,03441022 0,17864235 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03441022 0,17814055 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03441022 0,17764156 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03441022 0,17714535 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03441022 0,17665191 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03441022 0,17616121 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03441022 0,17567323 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03441022 0,17518794 GO:0033135|regulation of peptidyl-serine phosphorylation, ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03441022 0,17470533 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03441022 0,17422537 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03441022 0,17374804 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03441022 0,17327332 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03441022 0,17280119 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03441022 0,17233162 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03441022 0,1718646 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03441022 0,1714001 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03441022 0,1709381 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03441022 0,17047859 ! response to ATP GO:0033198 5 5 0,000 0,03441022 0,17002154 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03441022 0,16956694 ! regulation of appetite GO:0032098 5 5 0,000 0,03441022 0,16911476 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03441022 0,16866499 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03441022 0,1682176 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03441022 0,16777258 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03441022 0,16732991 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03441022 0,16688957 ! receptor clustering GO:0043113 5 5 0,000 0,03441022 0,16645154 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03441022 0,1660158 ! fear response GO:0042596 5 5 0,000 0,03441022 0,16558234 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03441022 0,16515114 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03441022 0,16472217 ! retinol metabolic process GO:0042572 5 5 0,000 0,03441022 0,16429543 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03441022 0,16387089 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03441022 0,16344855 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03441022 0,16302837 ! parturition GO:0007567 5 5 0,000 0,03441022 0,16261035 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03441022 0,16219447 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03441022 0,1617807 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03441022 0,16136905 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03441022 0,16095948 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03441022 0,16055199 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03441022 0,16014656 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03441022 0,15974316 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03441022 0,1593418 ! response to UV-B GO:0010224 5 5 0,000 0,03441022 0,15894245 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03441022 0,15854509 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03441022 0,15814972 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03441022 0,15775631 ! interaction with symbiont GO:0051702 5 5 0,000 0,03441022 0,15736485 ! cellular extravasation GO:0045123 5 5 0,000 0,03441022 0,15697534 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03441022 0,15658774 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03441022 0,15620206 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03441022 0,15581827 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03441022 0,15543636 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03441022 0,15505632 ! response to amine stimulus GO:0014075 5 5 0,000 0,03441022 0,15467814 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03441022 0,15430179 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03441022 0,15392727 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03441022 0,15355457 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03441022 0,15318366 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03441022 0,15281454 ! neuron recognition GO:0008038 5 5 0,000 0,03441022 0,1524472 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03441022 0,15208162 ! hair follicle maturation GO:0048820 5 5 0,000 0,03441022 0,15171779 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03441022 0,15135569 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03441022 0,15099532 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03441022 0,15063666 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03441022 0,15027971 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03441022 0,14992443 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03441022 0,14957084 ! postreplication repair GO:0006301 5 5 0,000 0,03441022 0,14921891 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03441022 0,14886863 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03441022 0,14851999 ! histone methylation GO:0016571 5 5 0,000 0,03441022 0,14817298 ! DNA methylation GO:0006306 5 5 0,000 0,03441022 0,14782759 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03441022 0,1474838 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03441022 0,14714161 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03441022 0,14680101 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03441022 0,14646198 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03441022 0,14612451 ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03441022 0,14578859 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03441022 0,14545421 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03441022 0,14512136 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03441022 0,14479004 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03441022 0,14446022 ! sterol catabolic process GO:0016127 5 5 0,000 0,03441022 0,1441319 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03441022 0,14380507 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03441022 0,14347972 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03441022 0,14315584 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03441022 0,14283341 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03441022 0,14251244 ! zymogen activation GO:0031638 5 5 0,000 0,03441022 0,14219291 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03441022 0,1418748 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03441022 0,14155812 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03441022 0,14124284 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,03441022 0,14092897 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03441022 0,14061649 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03441022 0,14030539 ! nucleosome positioning GO:0016584 5 5 0,000 0,03441022 0,13999566 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03441022 0,1396873 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03441022 0,1393803 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03441022 0,13907464 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03441022 0,13877032 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03441022 0,13846733 ! NADPH regeneration GO:0006740 5 5 0,000 0,03441022 0,13816566 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03441022 0,1378653 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03441022 0,13756624 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03441022 0,13726848 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03441022 0,136972 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03441022 0,1366768 ! sarcomere organization GO:0045214 5 5 0,000 0,03441022 0,13638287 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03441022 0,13609021 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03441022 0,13579879 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03441022 0,13550862 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03441022 0,13521969 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03441022 0,13493199 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03441022 0,13464551 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03441022 0,13436025 ! spleen development GO:0048536 5 5 0,000 0,03441022 0,13407619 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03441022 0,13379332 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03441022 0,13351165 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03441022 0,13323117 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03441022 0,13295186 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03441022 0,13267372 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03441022 0,13239673 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03441022 0,13212091 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03441022 0,13184623 ! ATP catabolic process GO:0006200 5 5 0,000 0,03441022 0,13157269 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03441022 0,13130028 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03441022 0,131029 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03441022 0,13075884 ! embryonic gut development GO:0048566 5 5 0,000 0,03441022 0,13048979 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03441022 0,13022184 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03441022 0,12995499 ! activation of innate immune response GO:0002218 5 5 0,000 0,03441022 0,12968924 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03441022 0,12942456 ! catecholamine transport GO:0051937 5 5 0,000 0,03441022 0,12916097 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03441022 0,12889845 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03441022 0,12863699 ! muscle adaptation GO:0043500 5 5 0,000 0,03441022 0,12837659 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03441022 0,12811724 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03441022 0,12785894 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03441022 0,12760168 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03441022 0,12734545 ! defense response to fungus GO:0050832 5 5 0,000 0,03441022 0,12709025 ! lysogeny GO:0030069 5 5 0,000 0,03441022 0,12683607 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03441022 0,12658291 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03441022 0,12633075 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03441022 0,12607959 ! response to nicotine GO:0035094 5 5 0,000 0,03441022 0,12582944 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03441022 0,12558027 ! mitochondrion localization GO:0051646 5 5 0,000 0,03441022 0,12533209 ! nucleus localization GO:0051647 5 5 0,000 0,03441022 0,12508488 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03441022 0,12483865 ! reproductive structure development GO:0048608 43 43 1,000 0,03589876 0,12998314 ! mitochondrion organization GO:0007005 44 43 1,000 0,03589876 0,12972827 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,03589876 0,1294744 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03589876 0,12922152 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03744375 0,13452014 ! protein import into nucleus GO:0006606 44 44 1,000 0,03744375 0,13425843 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03744375 0,13399773 ! vitamin metabolic process GO:0006766 44 44 1,000 0,03744375 0,13373805 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,03901403 0,13907709 ! nuclear import GO:0051170 45 45 1,000 0,03901403 0,13880861 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,04060919 0,14420566 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,04060919 0,14392834 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04060919 0,14365209 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,04060919 0,14337689 ! regulation of membrane potential GO:0042391 46 46 1,000 0,04060919 0,14310275 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04115179 0,14473808 ! axon extension GO:0048675 7 6 0,000 0,04115179 0,14446239 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04115179 0,14418774 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,04115179 0,14391414 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,04115179 0,14364158 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04115179 0,14337004 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04115179 0,14309954 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04115179 0,14283004 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04115179 0,14256157 ! virus-host interaction GO:0019048 6 6 0,000 0,04115179 0,1422941 ! regulation of S phase GO:0033261 6 6 0,000 0,04115179 0,14202763 ! myotube differentiation GO:0014902 6 6 0,000 0,04115179 0,14176216 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04115179 0,14149767 ! bone remodeling GO:0046849 6 6 0,000 0,04115179 0,14123418 ! N-glycan processing GO:0006491 6 6 0,000 0,04115179 0,14097166 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04115179 0,14071012 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04115179 0,14044954 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04115179 0,14018993 ! RNA methylation GO:0001510 6 6 0,000 0,04115179 0,13993128 ! cartilage condensation GO:0001502 7 6 0,000 0,04115179 0,13967358 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04115179 0,13941683 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04115179 0,13916102 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,04115179 0,13890614 ! artery development GO:0060840 6 6 0,000 0,04115179 0,1386522 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04115179 0,13839919 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04115179 0,13814709 ! androgen metabolic process GO:0008209 6 6 0,000 0,04115179 0,13789592 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04115179 0,13764565 ! limbic system development GO:0021761 7 6 0,000 0,04115179 0,13739629 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04115179 0,13714784 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04115179 0,13690028 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04115179 0,13665361 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04115179 0,13640783 ! pathogenesis GO:0009405 6 6 0,000 0,04115179 0,13616293 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04115179 0,13591891 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04115179 0,13567577 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04115179 0,13543349 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04115179 0,13519207 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04115179 0,13495152 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04115179 0,13471182 ! arginine metabolic process GO:0006525 6 6 0,000 0,04115179 0,13447297 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04115179 0,13423496 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04115179 0,1339978 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04115179 0,13376147 GO:0010833|telomere maintenance via telomere lengthening, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04115179 0,13352597 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04115179 0,13329131 ! ER overload response GO:0006983 6 6 0,000 0,04115179 0,13305746 ! V(D)J recombination GO:0033151 6 6 0,000 0,04115179 0,13282444 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04115179 0,13259223 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04115179 0,13236083 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04115179 0,13213023 ! regulation of heart rate GO:0002027 6 6 0,000 0,04115179 0,13190044 ! lipid digestion GO:0044241 6 6 0,000 0,04115179 0,13167145 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04115179 0,13144325 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04115179 0,13121584 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04115179 0,13098921 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04115179 0,13076337 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04115179 0,1305383 ! ruffle organization GO:0031529 6 6 0,000 0,04115179 0,13031401 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,04115179 0,13009049 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04115179 0,12986773 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04115179 0,12964573 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04115179 0,12942449 ! L-amino acid transport GO:0015807 6 6 0,000 0,04115179 0,12920401 ! bone mineralization GO:0030282 6 6 0,000 0,04115179 0,12898427 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04115179 0,12876529 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04115179 0,12854704 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04115179 0,12832953 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04115179 0,12811276 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04115179 0,12789672 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04115179 0,1276814 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04115179 0,12746681 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04115179 0,12725294 ! regulation of organ growth GO:0046620 6 6 0,000 0,04115179 0,12703979 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04115179 0,12682735 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04115179 0,12661562 ! response to dsRNA GO:0043331 6 6 0,000 0,04115179 0,12640459 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04115179 0,12619427 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04115179 0,12598464 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04115179 0,12577571 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04115179 0,12556747 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04115179 0,12535992 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04115179 0,12515306 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04115179 0,12494688 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04115179 0,12474137 ! erythrocyte development GO:0048821 6 6 0,000 0,04115179 0,12453654 ! renal water homeostasis GO:0003091 6 6 0,000 0,04115179 0,12433238 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04115179 0,12412889 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04115179 0,12392607 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04115179 0,1237239 ! ribosome assembly GO:0042255 6 6 0,000 0,04115179 0,1235224 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04115179 0,12332155 ! diencephalon development GO:0021536 6 6 0,000 0,04115179 0,12312135 ! fucose catabolic process GO:0019317 6 6 0,000 0,04115179 0,1229218 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04115179 0,1227229 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04115179 0,12252464 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04115179 0,12232702 ! regulation of cell division GO:0051302 6 6 0,000 0,04115179 0,12213004 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04115179 0,12193369 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04115179 0,12173797 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04115179 0,12154287 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04115179 0,12134841 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04115179 0,12115456 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04115179 0,12096133 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04115179 0,12076872 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04115179 0,12057671 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04115179 0,12038532 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04115179 0,12019454 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04115179 0,12000436 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04115179 0,11981478 ! thymus development GO:0048538 6 6 0,000 0,04115179 0,11962579 ! lymph node development GO:0048535 6 6 0,000 0,04115179 0,11943741 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04115179 0,11924961 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04115179 0,11906241 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04115179 0,11887579 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04115179 0,11868976 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04115179 0,1185043 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04115179 0,11831943 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04115179 0,11813513 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04115179 0,11795141 ! alditol metabolic process GO:0019400 6 6 0,000 0,04115179 0,11776825 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04115179 0,11758566 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04115179 0,11740364 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04115179 0,11722218 ! localization within membrane GO:0051668 6 6 0,000 0,04115179 0,11704129 ! amine transport GO:0015837 47 47 1,000 0,04222882 0,11991944 ! regulation of catabolic process GO:0009894 48 47 1,000 0,04222882 0,11973495 ! actin filament organization GO:0007015 50 48 1,000 0,04387252 0,12420439 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04387252 0,1240139 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,04553989 0,1285299 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 1,000 0,04553989 0,12833337 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,04723054 0,13289448 ! negative regulation of transport GO:0051051 51 50 1,000 0,04723054 0,1326919 ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,04723054 0,13248993 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,04723054 0,13228858 ! respiratory burst GO:0045730 7 7 0,000 0,04784727 0,13381262 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04784727 0,13360988 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04784727 0,13340774 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04784727 0,13320622 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04784727 0,13300531 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04784727 0,132805 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04784727 0,13260529 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04784727 0,13240618 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04784727 0,13220767 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04784727 0,13200976 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04784727 0,13181244 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04784727 0,1316157 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04784727 0,13141955 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04784727 0,13122399 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04784727 0,131029 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04784727 0,1308346 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04784727 0,13064077 ! axis specification GO:0009798 7 7 0,000 0,04784727 0,13044751 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04784727 0,13025483 ! visual behavior GO:0007632 7 7 0,000 0,04784727 0,13006271 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04784727 0,12987116 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04784727 0,12968018 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04784727 0,12948975 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04784727 0,12929988 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04784727 0,12911057 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04784727 0,12892181 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04784727 0,1287336 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04784727 0,12854595 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04784727 0,12835883 ! digestive system development GO:0055123 7 7 0,000 0,04784727 0,12817227 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04784727 0,12798624 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04784727 0,12780075 ! protein targeting to ER GO:0045047 8 7 0,000 0,04784727 0,1276158 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04784727 0,12743139 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04784727 0,1272475 ! endoderm development GO:0007492 7 7 0,000 0,04784727 0,12706415 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04784727 0,12688132 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04784727 0,12669902 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04784727 0,12651724 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04784727 0,12633599 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04784727 0,12615525 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04784727 0,12597503 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04784727 0,12579532 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04784727 0,12561612 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04784727 0,12543744 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04784727 0,12525926 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04784727 0,12508159 ! response to X-ray GO:0010165 7 7 0,000 0,04784727 0,12490442 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04784727 0,12472775 ! UV protection GO:0009650 7 7 0,000 0,04784727 0,12455158 ! DNA integration GO:0015074 7 7 0,000 0,04784727 0,12437591 ! myofibril assembly GO:0030239 7 7 0,000 0,04784727 0,12420073 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04784727 0,12402605 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04784727 0,12385185 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04784727 0,12367815 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04784727 0,12350493 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04784727 0,12333219 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04784727 0,12315994 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04784727 0,12298817 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04784727 0,12281688 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04784727 0,12264606 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04784727 0,12247572 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04784727 0,12230585 ! axon cargo transport GO:0008088 7 7 0,000 0,04784727 0,12213645 ! eating behavior GO:0042755 7 7 0,000 0,04784727 0,12196752 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04784727 0,12179906 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04784727 0,12163106 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04784727 0,12146352 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04784727 0,12129645 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04784727 0,12112983 ! cranial nerve development GO:0021545 7 7 0,000 0,04784727 0,12096368 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04784727 0,12079797 ! induction of an organ GO:0001759 7 7 0,000 0,04784727 0,12063272 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04784727 0,12046792 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04784727 0,12030357 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04784727 0,12013967 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04784727 0,11997622 ! platelet activation GO:0030168 8 7 0,000 0,04784727 0,11981321 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04784727 0,11965064 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04784727 0,11948851 ! natural killer cell activation GO:0030101 7 7 0,000 0,04784727 0,11932682 ! response to gamma radiation GO:0010332 8 7 0,000 0,04784727 0,11916557 ! NADP metabolic process GO:0006739 7 7 0,000 0,04784727 0,11900475 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04784727 0,11884437 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04784727 0,11868441 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04784727 0,11852489 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04784727 0,1183658 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04784727 0,11820713 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04784727 0,11804889 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04784727 0,11789107 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04784727 0,11773367 ! cell-cell recognition GO:0009988 8 7 0,000 0,04784727 0,11757669 ! hormone catabolic process GO:0042447 7 7 0,000 0,04784727 0,11742013 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04784727 0,11726399 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04784727 0,11710826 ! oxygen transport GO:0015671 7 7 0,000 0,04784727 0,11695294 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04784727 0,11679804 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04784727 0,11664354 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04784727 0,11648946 ! regulation of axon extension GO:0030516 7 7 0,000 0,04784727 0,11633578 ! cell killing GO:0001906 7 7 0,000 0,04784727 0,1161825 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04784727 0,11602963 ! adult feeding behavior GO:0008343 7 7 0,000 0,04784727 0,11587716 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04784727 0,11572509 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04784727 0,11557342 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04784727 0,11542215 ! response to cold GO:0009409 7 7 0,000 0,04784727 0,11527127 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,04894407 0,11775969 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,04894407 0,11760615 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,0506801 0,12161903 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,0506801 0,12146088 ! response to light stimulus GO:0009416 53 52 1,000 0,0506801 0,12130314 ! sodium ion transport GO:0006814 53 53 1,000 0,05243824 0,12534847 ! regulation of T cell activation GO:0050863 53 53 1,000 0,05243824 0,1251861 ! regulation of protein transport GO:0051223 53 53 1,000 0,05243824 0,12502416 GO:0070201|regulation of establishment of protein localization, ! response to hypoxia GO:0001666 53 53 1,000 0,05243824 0,12486263 ! response to oxygen levels GO:0070482 55 54 1,000 0,05421812 0,12893418 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05449696 0,12943028 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05449696 0,12926371 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05449696 0,12909756 ! positive regulation of translation GO:0045727 8 8 0,000 0,05449696 0,12893184 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05449696 0,12876654 ! superoxide anion generation GO:0042554 8 8 0,000 0,05449696 0,12860167 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05449696 0,12843721 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05449696 0,12827318 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05449696 0,12810957 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05449696 0,12794637 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05449696 0,12778359 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05449696 0,12762122 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,05449696 0,12745927 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05449696 0,12729772 ! zinc ion transport GO:0006829 8 8 0,000 0,05449696 0,12713658 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05449696 0,12697585 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05449696 0,12681553 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05449696 0,12665561 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05449696 0,1264961 ! lipid localization GO:0010876 8 8 0,000 0,05449696 0,12633698 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05449696 0,12617827 ! response to cAMP GO:0051591 8 8 0,000 0,05449696 0,12601995 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05449696 0,12586203 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05449696 0,12570451 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05449696 0,12554738 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05449696 0,12539064 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05449696 0,12523429 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05449696 0,12507833 ! sensory perception of taste GO:0050909 8 8 0,000 0,05449696 0,12492276 ! organelle fusion GO:0048284 8 8 0,000 0,05449696 0,12476758 ! pancreas development GO:0031016 8 8 0,000 0,05449696 0,12461278 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05449696 0,12445837 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05449696 0,12430433 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05449696 0,12415068 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05449696 0,12399741 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05449696 0,12384451 ! sperm motility GO:0030317 8 8 0,000 0,05449696 0,123692 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05449696 0,12353985 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05449696 0,12338808 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05449696 0,12323669 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05449696 0,12308566 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05449696 0,12293501 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05449696 0,12278472 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05449696 0,1226348 ! Golgi organization GO:0007030 8 8 0,000 0,05449696 0,12248525 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05449696 0,12233605 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05449696 0,12218723 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,05449696 0,12203876 ! fructose metabolic process GO:0006000 8 8 0,000 0,05449696 0,12189066 ! mannose metabolic process GO:0006013 9 8 0,000 0,05449696 0,12174291 ! NAD metabolic process GO:0019674 8 8 0,000 0,05449696 0,12159552 ! sex determination GO:0007530 8 8 0,000 0,05449696 0,12144849 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05449696 0,12130181 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05449696 0,12115549 ! response to fungus GO:0009620 8 8 0,000 0,05449696 0,12100952 ! stem cell differentiation GO:0048863 8 8 0,000 0,05449696 0,1208639 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05449696 0,12071863 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05449696 0,12057371 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05449696 0,12042914 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05449696 0,12028491 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05449696 0,12014103 ! vasoconstriction GO:0042310 8 8 0,000 0,05449696 0,11999749 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05449696 0,1198543 ! muscle cell development GO:0055001 8 8 0,000 0,05449696 0,11971144 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05449696 0,11956893 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05449696 0,11942675 ! sensory perception of pain GO:0019233 8 8 0,000 0,05449696 0,11928492 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05449696 0,11914342 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05449696 0,11900225 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05449696 0,11886142 ! chromatin silencing GO:0006342 8 8 0,000 0,05449696 0,11872092 ! tissue regeneration GO:0042246 8 8 0,000 0,05449696 0,11858076 ! salivary gland development GO:0007431 8 8 0,000 0,05449696 0,11844092 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05449696 0,11830141 ! T cell homeostasis GO:0043029 8 8 0,000 0,05449696 0,11816224 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05449696 0,11802339 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,05449696 0,11788486 ! water homeostasis GO:0030104 8 8 0,000 0,05449696 0,11774666 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05449696 0,11760878 ! acid secretion GO:0046717 8 8 0,000 0,05449696 0,11747123 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,05449696 0,117334 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05449696 0,11719708 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05449696 0,11706049 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05449696 0,11692422 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05449696 0,11678826 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05449696 0,11665261 ! regulation of RNA stability GO:0043487 8 8 0,000 0,05449696 0,11651729 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05449696 0,11638227 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05449696 0,11624757 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05449696 0,11611318 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05449696 0,1159791 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05449696 0,11584533 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05449696 0,11571187 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05449696 0,11557871 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05449696 0,11544586 ! developmental induction GO:0031128 8 8 0,000 0,05449696 0,11531332 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05449696 0,11518108 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05449696 0,11504914 ! actin filament polymerization GO:0030041 9 8 0,000 0,05449696 0,11491751 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05449696 0,11478617 ! peptide hormone processing GO:0016486 8 8 0,000 0,05449696 0,11465514 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05449696 0,1145244 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05449696 0,11439396 ! in utero embryonic development GO:0001701 55 55 1,000 0,05601936 0,11745583 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,05601936 0,11732236 ! regulation of protein localization GO:0032880 58 57 1,000 0,05968444 0,12485633 ! lactation GO:0007595 10 9 0,000 0,06110117 0,12767513 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06110117 0,12753054 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06110117 0,12738627 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06110117 0,12724233 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06110117 0,12709872 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06110117 0,12695543 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,06110117 0,12681246 ! viral genome replication GO:0019079 9 9 0,000 0,06110117 0,12666981 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06110117 0,12652749 ! copper ion transport GO:0006825 9 9 0,000 0,06110117 0,12638548 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06110117 0,12624379 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06110117 0,12610242 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06110117 0,12596137 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06110117 0,12582063 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06110117 0,12568021 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06110117 0,12554009 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06110117 0,12540029 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06110117 0,12526081 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06110117 0,12512163 ! response to alkaloid GO:0043279 10 9 0,000 0,06110117 0,12498276 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06110117 0,1248442 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06110117 0,12470594 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,06110117 0,12456799 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06110117 0,12443035 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06110117 0,12429301 ! response to ethanol GO:0045471 9 9 0,000 0,06110117 0,12415597 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06110117 0,12401923 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06110117 0,1238828 ! methionine metabolic process GO:0006555 9 9 0,000 0,06110117 0,12374666 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06110117 0,12361083 ! cerebral cortex development GO:0021987 9 9 0,000 0,06110117 0,12347529 ! response to osmotic stress GO:0006970 9 9 0,000 0,06110117 0,12334005 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06110117 0,1232051 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06110117 0,12307045 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06110117 0,1229361 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06110117 0,12280203 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06110117 0,12266826 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06110117 0,12253478 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06110117 0,12240159 GO:0015800|acidic amino acid transport, ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06110117 0,12226869 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06110117 0,12213608 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06110117 0,12200375 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06110117 0,12187171 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06110117 0,12173996 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06110117 0,12160849 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,06110117 0,12147731 ! DNA replication initiation GO:0006270 9 9 0,000 0,06110117 0,12134641 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06110117 0,12121578 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06110117 0,12108545 ! regulation of cellular pH GO:0030641 9 9 0,000 0,06110117 0,12095539 ! histone acetylation GO:0016573 9 9 0,000 0,06110117 0,12082561 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06110117 0,1206961 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06110117 0,12056688 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06110117 0,12043793 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06110117 0,12030926 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06110117 0,12018086 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06110117 0,12005273 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,06110117 0,11992488 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06110117 0,1197973 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,06110117 0,11966999 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06110117 0,11954296 ! collagen catabolic process GO:0030574 9 9 0,000 0,06110117 0,11941619 ! purine base metabolic process GO:0006144 9 9 0,000 0,06110117 0,11928969 ! gas transport GO:0015669 9 9 0,000 0,06110117 0,11916345 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06110117 0,11903749 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06110117 0,11891179 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06110117 0,11878635 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06110117 0,11866118 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,06110117 0,11853628 ! defense response to virus GO:0051607 9 9 0,000 0,06110117 0,11841163 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06110117 0,11828725 ! actin filament-based movement GO:0030048 9 9 0,000 0,06110117 0,11816313 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06110117 0,11803927 ! carboxylic acid transport GO:0046942 59 59 1,000 0,06343058 0,12241106 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 1,000 0,06343058 0,12228302 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,06343058 0,12215524 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,06533315 0,12568789 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,06725492 0,12925007 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,06725492 0,12911543 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06766021 0,12975834 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06766021 0,12962346 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06766021 0,12948886 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06766021 0,12935453 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06766021 0,12922049 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06766021 0,12908672 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06766021 0,12895323 ! neuron maturation GO:0042551 10 10 0,000 0,06766021 0,12882001 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06766021 0,12868707 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06766021 0,1285544 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06766021 0,12842201 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06766021 0,12828989 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06766021 0,12815804 ! hormone secretion GO:0046879 10 10 0,000 0,06766021 0,12802646 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06766021 0,12789515 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06766021 0,12776411 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,06766021 0,12763334 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06766021 0,12750283 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06766021 0,12737259 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06766021 0,12724262 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06766021 0,12711291 ! glial cell development GO:0021782 10 10 0,000 0,06766021 0,12698347 ! phototransduction GO:0007602 11 10 0,000 0,06766021 0,12685429 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06766021 0,12672538 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06766021 0,12659672 ! fat cell differentiation GO:0045444 10 10 0,000 0,06766021 0,12646833 ! myoblast differentiation GO:0045445 10 10 0,000 0,06766021 0,12634019 ! centrosome cycle GO:0007098 10 10 0,000 0,06766021 0,12621232 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06766021 0,1260847 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06766021 0,12595734 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06766021 0,12583024 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06766021 0,1257034 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06766021 0,12557681 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06766021 0,12545047 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06766021 0,12532439 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06766021 0,12519856 ! plasma membrane organization GO:0007009 10 10 0,000 0,06766021 0,12507299 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06766021 0,12494766 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06766021 0,12482259 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06766021 0,12469777 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06766021 0,1245732 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06766021 0,12444887 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06766021 0,12432479 ! exocrine system development GO:0035272 10 10 0,000 0,06766021 0,12420097 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06766021 0,12407738 ! embryo implantation GO:0007566 11 10 0,000 0,06766021 0,12395404 ! regulation of protein binding GO:0043393 11 10 0,000 0,06766021 0,12383095 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06766021 0,1237081 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06766021 0,1235855 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06766021 0,12346314 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,06766021 0,12334102 ! protein export from nucleus GO:0006611 10 10 0,000 0,06766021 0,12321914 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06766021 0,1230975 ! cytolysis GO:0019835 10 10 0,000 0,06766021 0,1229761 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06766021 0,12285495 GO:0030501|positive regulation of bone mineralization, ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06766021 0,12273402 ! histone deacetylation GO:0016575 10 10 0,000 0,06766021 0,12261334 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06766021 0,1224929 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06766021 0,12237269 ! gland morphogenesis GO:0022612 10 10 0,000 0,06766021 0,12225271 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06766021 0,12213298 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06766021 0,12201347 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06766021 0,1218942 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06766021 0,12177517 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06766021 0,12165636 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06766021 0,12153779 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06766021 0,12141944 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06766021 0,12130133 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06766021 0,12118345 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06766021 0,1210658 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06766021 0,12094837 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06766021 0,12083117 ! nerve development GO:0021675 10 10 0,000 0,06766021 0,1207142 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06766021 0,12059746 ! gut development GO:0048565 10 10 0,000 0,06766021 0,12048094 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06766021 0,12036464 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,06766021 0,12024857 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,06766021 0,12013273 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06766021 0,1200171 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06766021 0,1199017 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06766021 0,11978652 ! protein stabilization GO:0050821 10 10 0,000 0,06766021 0,11967156 ! lipid transport GO:0006869 62 62 1,000 0,06919553 0,12226977 ! axonogenesis GO:0007409 66 62 1,000 0,06919553 0,12215265 ! protein import GO:0017038 62 62 1,000 0,06919553 0,12203576 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,06919553 0,12191909 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,07115465 0,12525122 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,07313194 0,12860894 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07417438 0,1303178 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07417438 0,13019369 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07417438 0,13006981 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07417438 0,12994617 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07417438 0,12982277 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07417438 0,1296996 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07417438 0,12957666 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07417438 0,12945395 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07417438 0,12933148 ! signal complex assembly GO:0007172 11 11 0,000 0,07417438 0,12920924 ! microtubule-based transport GO:0010970 11 11 0,000 0,07417438 0,12908723 ! endothelial cell migration GO:0043542 11 11 0,000 0,07417438 0,12896545 ! peroxisomal transport GO:0043574 11 11 0,000 0,07417438 0,1288439 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07417438 0,12872257 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,07417438 0,12860148 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,07417438 0,12848061 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,07417438 0,12835998 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07417438 0,12823956 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07417438 0,12811938 ! T cell proliferation GO:0042098 11 11 0,000 0,07417438 0,12799941 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07417438 0,12787968 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07417438 0,12776016 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07417438 0,12764087 ! spinal cord development GO:0021510 11 11 0,000 0,07417438 0,1275218 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07417438 0,12740296 ! cellular response to starvation GO:0009267 11 11 0,000 0,07417438 0,12728433 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,07417438 0,12716593 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07417438 0,12704775 ! digestive system process GO:0022600 11 11 0,000 0,07417438 0,12692978 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07417438 0,12681204 ! fucose metabolic process GO:0006004 11 11 0,000 0,07417438 0,12669451 ! membrane budding GO:0006900 11 11 0,000 0,07417438 0,1265772 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07417438 0,12646011 ! monoamine transport GO:0015844 11 11 0,000 0,07417438 0,12634323 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07417438 0,12622657 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07417438 0,12611012 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07417438 0,12599389 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07417438 0,12587788 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07417438 0,12576207 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07417438 0,12564648 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,07417438 0,12553111 ! membrane depolarization GO:0051899 11 11 0,000 0,07417438 0,12541594 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07417438 0,12530098 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07417438 0,12518624 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,07417438 0,12507171 ! oogenesis GO:0048477 11 11 0,000 0,07417438 0,12495738 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07417438 0,12484326 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07417438 0,12472936 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 0,000 0,07417438 0,12461566 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07417438 0,12450216 ! hindbrain development GO:0030902 11 11 0,000 0,07417438 0,12438888 ! steroid catabolic process GO:0006706 11 11 0,000 0,07417438 0,12427579 ! endocrine process GO:0050886 11 11 0,000 0,07417438 0,12416292 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07417438 0,12405025 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07417438 0,12393778 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07417438 0,12382552 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,07512706 0,12530241 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,07713967 0,12854287 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,07916945 0,13180605 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Ras protein signal transduction GO:0007265 69 67 1,000 0,07916945 0,13168709 ! translational initiation GO:0006413 12 12 0,000 0,08064397 0,13401879 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08064397 0,13389805 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08064397 0,13377753 ! initiation of viral infection GO:0019059 12 12 0,000 0,08064397 0,13365722 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08064397 0,13353714 ! iron ion transport GO:0006826 13 12 0,000 0,08064397 0,13341726 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08064397 0,13329761 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08064397 0,13317817 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08064397 0,13305894 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08064397 0,13293992 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,08064397 0,13282112 ! collagen metabolic process GO:0032963 12 12 0,000 0,08064397 0,13270253 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08064397 0,13258415 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08064397 0,13246598 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08064397 0,13234803 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08064397 0,13223028 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08064397 0,13211274 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08064397 0,13199541 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,08064397 0,13187829 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08064397 0,13176138 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08064397 0,13164467 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08064397 0,13152817 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08064397 0,13141188 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08064397 0,13129579 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08064397 0,13117991 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08064397 0,13106423 ! acute-phase response GO:0006953 12 12 0,000 0,08064397 0,13094875 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08064397 0,13083348 ! vacuolar transport GO:0007034 12 12 0,000 0,08064397 0,13071841 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08064397 0,13060354 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08064397 0,13048888 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08064397 0,13037441 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08064397 0,13026015 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08064397 0,13014609 ! male gonad development GO:0008584 12 12 0,000 0,08064397 0,13003222 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08064397 0,12991856 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08064397 0,12980509 ! renal system process GO:0003014 12 12 0,000 0,08064397 0,12969183 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08064397 0,12957876 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08064397 0,12946588 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,08064397 0,12935321 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08064397 0,12924072 ! pallium development GO:0021543 13 12 0,000 0,08064397 0,12912844 ! cell fate determination GO:0001709 12 12 0,000 0,08064397 0,12901635 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08064397 0,12890445 ! somitogenesis GO:0001756 13 12 0,000 0,08064397 0,12879275 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08064397 0,12868124 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08064397 0,12856992 ! detection of light stimulus GO:0009583 13 12 0,000 0,08064397 0,1284588 ! synaptogenesis GO:0007416 12 12 0,000 0,08064397 0,12834787 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08064397 0,12823713 ! hormone transport GO:0009914 12 12 0,000 0,08064397 0,12812658 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08064397 0,12801622 ! spermatid differentiation GO:0048515 13 12 0,000 0,08064397 0,12790605 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08064397 0,12779607 ! neural tube closure GO:0001843 13 12 0,000 0,08064397 0,12768628 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08064397 0,12757668 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08064397 0,12746727 ! regulation of translation GO:0006417 69 69 1,000 0,08327921 0,13151979 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,08327921 0,13140719 ! cell part morphogenesis GO:0032990 75 70 1,000 0,08535856 0,13457299 ! wound healing GO:0042060 74 70 1,000 0,08535856 0,13445797 ! growth GO:0040007 70 70 1,000 0,08535856 0,13434314 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,08706929 0,13691868 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08706929 0,13680196 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08706929 0,13668543 ! phenol metabolic process GO:0018958 13 13 0,000 0,08706929 0,1365691 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08706929 0,13645297 ! gluconeogenesis GO:0006094 13 13 0,000 0,08706929 0,13633704 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08706929 0,1362213 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08706929 0,13610576 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08706929 0,13599042 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08706929 0,13587527 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08706929 0,13576032 ! regeneration GO:0031099 13 13 0,000 0,08706929 0,13564556 ! keratinization GO:0031424 13 13 0,000 0,08706929 0,13553099 ! post-embryonic development GO:0009791 14 13 0,000 0,08706929 0,13541662 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08706929 0,13530244 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08706929 0,13518845 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08706929 0,13507466 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08706929 0,13496106 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,08706929 0,13484764 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,08706929 0,13473442 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,08706929 0,13462139 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08706929 0,13450855 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08706929 0,13439589 ! autophagy GO:0006914 13 13 0,000 0,08706929 0,13428343 ! receptor metabolic process GO:0043112 14 13 0,000 0,08706929 0,13417115 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08706929 0,13405906 ! ureteric bud development GO:0001657 13 13 0,000 0,08706929 0,13394716 ! cell aging GO:0007569 13 13 0,000 0,08706929 0,13383544 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,08706929 0,13372391 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,08706929 0,13361257 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,08706929 0,13350141 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08706929 0,13339044 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08706929 0,13327965 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08706929 0,13316904 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08706929 0,13305862 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08706929 0,13294838 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08706929 0,13283832 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08706929 0,13272845 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08706929 0,13261876 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08706929 0,13250924 ! vasodilation GO:0042311 14 13 0,000 0,08706929 0,13239991 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08706929 0,13229076 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08706929 0,13218179 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,08706929 0,132073 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,08706929 0,13196439 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08706929 0,13185595 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08706929 0,1317477 ! immunoglobulin production GO:0002377 13 13 0,000 0,08706929 0,13163962 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08706929 0,13153172 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08706929 0,13142399 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,08706929 0,13131644 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08706929 0,13120907 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08706929 0,13110188 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08706929 0,13099485 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08706929 0,13088801 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08706929 0,13078133 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08706929 0,13067483 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08706929 0,13056851 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08706929 0,13046235 ! telomere organization GO:0032200 13 13 0,000 0,08706929 0,13035637 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08706929 0,13025056 ! regulation of amine transport GO:0051952 13 13 0,000 0,08706929 0,13014493 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08706929 0,13003946 ! protein tetramerization GO:0051262 13 13 0,000 0,08706929 0,12993417 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,08745379 0,13040237 ! regulation of cell activation GO:0050865 71 71 1,000 0,08745379 0,13029695 ! neuron fate commitment GO:0048663 14 14 0,000 0,09345063 0,13911915 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09345063 0,13900687 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09345063 0,13889476 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09345063 0,13878284 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09345063 0,1386711 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,09345063 0,13855954 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09345063 0,13844816 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09345063 0,13833695 ! protein amino acid acylation GO:0043543 14 14 0,000 0,09345063 0,13822593 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09345063 0,13811508 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09345063 0,13800441 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09345063 0,13789392 ! vesicle docking GO:0048278 14 14 0,000 0,09345063 0,13778361 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09345063 0,13767347 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09345063 0,13756351 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09345063 0,13745372 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09345063 0,13734411 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09345063 0,13723467 ! hair cycle GO:0042633 14 14 0,000 0,09345063 0,1371254 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09345063 0,13701632 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09345063 0,1369074 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09345063 0,13679866 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09345063 0,13669009 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09345063 0,13658169 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09345063 0,13647346 ! primary neural tube formation GO:0014020 15 14 0,000 0,09345063 0,13636541 ! peptide cross-linking GO:0018149 14 14 0,000 0,09345063 0,13625752 ! regulation of behavior GO:0050795 14 14 0,000 0,09345063 0,13614981 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09345063 0,13604227 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09345063 0,13593489 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09345063 0,13582769 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09345063 0,13572065 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,09345063 0,13561379 ! collagen fibril organization GO:0030199 14 14 0,000 0,09345063 0,13550709 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09345063 0,13540056 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,09345063 0,13529419 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09345063 0,135188 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09345063 0,13508197 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09345063 0,1349761 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09345063 0,13487041 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09345063 0,13476487 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09345063 0,13465951 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09345063 0,1345543 ! response to oxidative stress GO:0006979 76 75 1,000 0,09598739 0,13809895 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,09815745 0,1411109 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,09978829 0,14334358 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09978829 0,14323194 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09978829 0,14312048 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09978829 0,14300919 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09978829 0,14289807 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09978829 0,14278712 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09978829 0,14267635 ! response to vitamin GO:0033273 15 15 0,000 0,09978829 0,14256575 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,09978829 0,14245532 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09978829 0,14234506 ! ovarian follicle development GO:0001541 15 15 0,000 0,09978829 0,14223497 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09978829 0,14212505 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09978829 0,1420153 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09978829 0,14190572 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09978829 0,14179631 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,09978829 0,14168707 ! heme metabolic process GO:0042168 15 15 0,000 0,09978829 0,14157799 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09978829 0,14146909 ! chromosome condensation GO:0030261 15 15 0,000 0,09978829 0,14136035 ! response to starvation GO:0042594 15 15 0,000 0,09978829 0,14125178 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09978829 0,14114337 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09978829 0,14103513 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09978829 0,14092706 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09978829 0,14081915 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09978829 0,14071141 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09978829 0,14060383 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,09978829 0,14049642 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09978829 0,14038917 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09978829 0,14028209 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09978829 0,14017516 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09978829 0,1400684 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09978829 0,13996181 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,09978829 0,13985537 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09978829 0,1397491 ! protein homooligomerization GO:0051260 15 15 0,000 0,09978829 0,13964299 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09978829 0,13953704 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,10034157 0,14020433 ! regulation of protein modification process GO:0031399 79 78 1,000 0,10253947 0,14316685 ! nuclear transport GO:0051169 79 79 1,000 0,10475085 0,14614369 GO:0006913|nucleocytoplasmic transport, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,10608256 0,14788968 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10608256 0,14777789 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10608256 0,14766628 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10608256 0,14755483 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10608256 0,14744356 ! learning GO:0007612 16 16 0,000 0,10608256 0,14733244 ! circadian rhythm GO:0007623 16 16 0,000 0,10608256 0,1472215 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10608256 0,14711073 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,10608256 0,14700012 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10608256 0,14688967 ! vesicle targeting GO:0006903 17 16 0,000 0,10608256 0,1467794 ! segmentation GO:0035282 17 16 0,000 0,10608256 0,14666928 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10608256 0,14655934 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10608256 0,14644955 ! positive regulation of cell development GO:0010720 16 16 0,000 0,10608256 0,14633994 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,10608256 0,14623048 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10608256 0,14612119 ! cell fate specification GO:0001708 16 16 0,000 0,10608256 0,14601206 ! pentose metabolic process GO:0019321 16 16 0,000 0,10608256 0,1459031 ! fatty acid transport GO:0015908 16 16 0,000 0,10608256 0,1457943 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10608256 0,14568566 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,10608256 0,14557718 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,10608256 0,14546886 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10608256 0,14536071 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10608256 0,14525271 ! polyol metabolic process GO:0019751 16 16 0,000 0,10608256 0,14514488 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10608256 0,14503721 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10608256 0,14492969 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10608256 0,14482234 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10608256 0,14471514 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10608256 0,1446081 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10608256 0,14450122 ! regulation of coagulation GO:0050818 17 16 0,000 0,10608256 0,1443945 ! neuron projection development GO:0031175 85 80 1,000 0,10697544 0,14550239 ! tube development GO:0035295 83 81 1,000 0,10921295 0,14843618 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,11233373 0,15256526 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,11233373 0,15245292 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,11233373 0,15234074 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,11233373 0,15222872 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,11233373 0,15211687 ! leukocyte adhesion GO:0007159 17 17 0,000 0,11233373 0,15200519 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,11233373 0,15189366 ! sensory perception of smell GO:0007608 17 17 0,000 0,11233373 0,1517823 ! tissue remodeling GO:0048771 17 17 0,000 0,11233373 0,15167111 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,11233373 0,15156007 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,11233373 0,1514492 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,11233373 0,1513385 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,11233373 0,15122795 ! neural crest cell development GO:0014032 19 17 0,000 0,11233373 0,15111756 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,11233373 0,15100734 ! negative regulation of cell development GO:0010721 18 17 0,000 0,11233373 0,15089728 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,11233373 0,15078737 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,11233373 0,15067763 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,11233373 0,15056805 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,11233373 0,15045862 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,11233373 0,15034936 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,11233373 0,15024025 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,11233373 0,1501313 ! adult locomotory behavior GO:0008344 17 17 0,000 0,11233373 0,15002251 ! embryonic organ development GO:0048568 17 17 0,000 0,11233373 0,14991388 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,11233373 0,1498054 ! liver development GO:0001889 17 17 0,000 0,11233373 0,14969708 ! gene silencing GO:0016458 17 17 0,000 0,11233373 0,14958892 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,11372561 0,15133307 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,11600022 0,15424849 ! regulation of cellular localization GO:0060341 86 85 1,000 0,11828665 0,15717541 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11854209 0,15740135 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,11854209 0,15728803 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,11854209 0,15717487 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11854209 0,15706188 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11854209 0,15694905 ! membrane docking GO:0022406 18 18 0,000 0,11854209 0,15683638 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11854209 0,15672387 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,11854209 0,15661152 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,11854209 0,15649933 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11854209 0,15638731 ! striated muscle contraction GO:0006941 18 18 0,000 0,11854209 0,15627544 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,11854209 0,15616374 ! ceramide metabolic process GO:0006672 18 18 0,000 0,11854209 0,15605219 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,11854209 0,15594081 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,11854209 0,15582958 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11854209 0,15571851 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11854209 0,1556076 ! B cell differentiation GO:0030183 18 18 0,000 0,11854209 0,15549685 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,11854209 0,15538625 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11854209 0,15527581 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11854209 0,15516553 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,11854209 0,15505541 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,11854209 0,15494544 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11854209 0,15483563 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,12058464 0,15739199 GO:0006644|phospholipid metabolic process, ! heart development GO:0007507 90 87 1,000 0,12289392 0,16029264 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12470793 0,16254364 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12470793 0,16242877 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,12470793 0,16231406 ! regulation of pH GO:0006885 19 19 0,000 0,12470793 0,16219951 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,12470793 0,16208513 ! feeding behavior GO:0007631 19 19 0,000 0,12470793 0,1619709 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,12470793 0,16185684 ! peroxisome organization GO:0007031 19 19 0,000 0,12470793 0,16174293 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,12470793 0,16162919 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,12470793 0,16151561 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,12470793 0,16140218 ! metanephros development GO:0001656 19 19 0,000 0,12470793 0,16128892 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12470793 0,16117581 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,12470793 0,16106287 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12470793 0,16095008 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12470793 0,16083745 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12470793 0,16072497 ! regulation of protein stability GO:0031647 19 19 0,000 0,12470793 0,16061266 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,12470793 0,1605005 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12470793 0,16038849 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,12470793 0,16027665 ! eye morphogenesis GO:0048592 19 19 0,000 0,12470793 0,16016496 ! regulation of cell shape GO:0008360 21 19 0,000 0,12470793 0,16005342 ! response to heat GO:0009408 19 19 0,000 0,12470793 0,15994204 ! vesicle localization GO:0051648 20 19 0,000 0,12470793 0,15983081 ! male gamete generation GO:0048232 90 88 1,000 0,12521423 0,16036819 GO:0007283|spermatogenesis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,12988693 0,16623723 ! regulation of muscle development GO:0048634 21 20 0,000 0,13083153 0,16732998 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,13083153 0,16721394 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,13083153 0,16709806 ! negative regulation of binding GO:0051100 21 20 0,000 0,13083153 0,16698234 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,13083153 0,16686679 ! neural tube development GO:0021915 21 20 0,000 0,13083153 0,16675139 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,13083153 0,16663615 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13083153 0,16652107 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13083153 0,16640615 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13083153 0,16629138 ! chromatin remodeling GO:0006338 20 20 0,000 0,13083153 0,16617678 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13083153 0,16606233 ! female gamete generation GO:0007292 20 20 0,000 0,13083153 0,16594804 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,13083153 0,16583391 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13083153 0,16571993 ! RNA modification GO:0009451 20 20 0,000 0,13083153 0,16560612 ! single fertilization GO:0007338 21 20 0,000 0,13083153 0,16549245 ! regulation of B cell activation GO:0050864 20 20 0,000 0,13083153 0,16537895 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,1346007 0,1700268 ! mRNA catabolic process GO:0006402 21 21 0,000 0,13691317 0,17282944 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,13691317 0,17271114 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,13691317 0,17259301 ! Notch signaling pathway GO:0007219 22 21 0,000 0,13691317 0,17247504 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,13691317 0,17235723 ! ear morphogenesis GO:0042471 21 21 0,000 0,13691317 0,17223958 ! organic anion transport GO:0015711 21 21 0,000 0,13691317 0,17212209 ! spliceosome assembly GO:0000245 22 21 0,000 0,13691317 0,17200476 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,13691317 0,17188759 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,13691317 0,17177058 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,13691317 0,17165373 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,13691317 0,17153703 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,13691317 0,1714205 ! regulation of proteolysis GO:0030162 21 21 0,000 0,13691317 0,17130413 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,13691317 0,17118791 ! regulation of response to stress GO:0080134 97 94 1,000 0,13935357 0,17412111 ! epidermis development GO:0008544 94 94 1,000 0,13935357 0,17400314 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,14295314 0,17837688 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,14295314 0,17825619 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,14295314 0,17813566 ! regulation of ion transport GO:0043269 22 22 0,000 0,14295314 0,1780153 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,14295314 0,1778951 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,14295314 0,17777506 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,14295314 0,17765519 ! ovulation cycle process GO:0022602 22 22 0,000 0,14295314 0,17753548 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,14295314 0,17741592 ! cell chemotaxis GO:0060326 23 22 0,000 0,14295314 0,17729653 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,14295314 0,1771773 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14295314 0,17705823 ! biopolymer methylation GO:0043414 22 22 0,000 0,14295314 0,17693932 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14295314 0,17682057 ! detection of external stimulus GO:0009581 23 22 0,000 0,14295314 0,17670198 ! neuron migration GO:0001764 22 22 0,000 0,14295314 0,17658354 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14295314 0,17646527 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14295314 0,17634715 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,14295314 0,17622919 ! aerobic respiration GO:0009060 22 22 0,000 0,14295314 0,17611139 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14295314 0,17599375 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,14895172 0,18325636 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,14895172 0,18313411 ! viral infectious cycle GO:0019058 23 23 0,000 0,14895172 0,18301202 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,14895172 0,18289009 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,14895172 0,18276833 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,14895172 0,18264672 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,14895172 0,18252528 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,14895172 0,182404 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,14895172 0,18228289 ! endocrine system development GO:0035270 23 23 0,000 0,14895172 0,18216193 ! female gonad development GO:0008585 23 23 0,000 0,14895172 0,18204113 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,14895172 0,18192049 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,14895172 0,18180002 ! cell projection assembly GO:0030031 25 23 0,000 0,14895172 0,1816797 ! endocytosis GO:0006897 99 98 1,000 0,1489689 0,18158048 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,1489689 0,18146047 ! blood circulation GO:0008015 99 98 1,000 0,1489689 0,18134061 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 1,000 0,1513942 0,18417129 ! ectoderm development GO:0007398 99 99 1,000 0,1513942 0,18404981 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,15382762 0,18688484 ! mitochondrial transport GO:0006839 24 24 0,000 0,15490919 0,18807485 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,15490919 0,18795104 ! glucose homeostasis GO:0042593 24 24 0,000 0,15490919 0,18782739 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,15490919 0,1877039 ! T cell differentiation GO:0030217 24 24 0,000 0,15490919 0,18758057 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,15490919 0,18745741 ! ovulation cycle GO:0042698 24 24 0,000 0,15490919 0,1873344 ! fertilization GO:0009566 25 24 0,000 0,15490919 0,18721156 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,15490919 0,18708888 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,15490919 0,18696636 ! glucan metabolic process GO:0044042 25 24 0,000 0,15490919 0,186844 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,16082581 0,19385347 ! negative regulation of secretion GO:0051048 26 25 0,000 0,16082581 0,19372677 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,16082581 0,19360024 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,16082581 0,19347387 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,16082581 0,19334766 ! cellular component disassembly GO:0022411 26 25 0,000 0,16082581 0,19322162 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,16082581 0,19309574 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,16082581 0,19297003 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,16082581 0,19284448 ! excretion GO:0007588 25 25 0,000 0,16082581 0,19271909 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,16082581 0,19259387 ! gastrulation GO:0007369 25 25 0,000 0,16082581 0,19246881 ! heart morphogenesis GO:0003007 25 25 0,000 0,16082581 0,19234391 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,16082581 0,19221917 ! regulation of endocytosis GO:0030100 25 25 0,000 0,16082581 0,1920946 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,16082581 0,19197018 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,16082581 0,19184593 ! positive regulation of binding GO:0051099 27 26 0,000 0,16670186 0,19872674 ! positive regulation of defense response GO:0031349 26 26 0,000 0,16670186 0,19859828 ! glycolysis GO:0006096 26 26 0,000 0,16670186 0,19846998 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,16670186 0,19834185 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,16670186 0,19821389 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16670186 0,19808609 ! cellular defense response GO:0006968 26 26 0,000 0,16670186 0,19795846 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16670186 0,19783099 ! double-strand break repair GO:0006302 27 26 0,000 0,16670186 0,19770369 ! regulation of protein secretion GO:0050708 26 26 0,000 0,16670186 0,19757655 ! germ cell development GO:0007281 27 26 0,000 0,16670186 0,19744957 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16670186 0,19732276 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,16670186 0,19719611 ! chloride transport GO:0006821 27 27 0,000 0,17253762 0,20396847 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,17253762 0,20383772 ! learning or memory GO:0007611 28 27 0,000 0,17253762 0,20370714 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,17253762 0,20357672 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,17253762 0,20344648 ! peptide metabolic process GO:0006518 29 27 0,000 0,17253762 0,20331639 ! activation of caspase activity GO:0006919 27 27 0,000 0,17253762 0,20318648 ! mesenchymal cell development GO:0014031 29 27 0,000 0,17253762 0,20305673 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,17253762 0,20292715 ! defense response to bacterium GO:0042742 27 27 0,000 0,17253762 0,20279773 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,17253762 0,20266848 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,17253762 0,20253939 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,17833336 0,20920967 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,17833336 0,20907658 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,17833336 0,20894367 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,17833336 0,20881092 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,17833336 0,20867834 ! histone modification GO:0016570 28 28 0,000 0,17833336 0,20854593 ! developmental growth GO:0048589 28 28 0,000 0,17833336 0,20841369 ! cartilage development GO:0051216 29 28 0,000 0,17833336 0,20828161 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,18408935 0,21486806 ! viral reproductive process GO:0022415 29 29 0,000 0,18408935 0,21473207 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,18408935 0,21459625 ! leukocyte migration GO:0050900 30 29 0,000 0,18408935 0,2144606 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,18408935 0,21432512 ! antigen processing and presentation GO:0019882 29 29 0,000 0,18408935 0,21418981 ! tRNA processing GO:0008033 29 29 0,000 0,18408935 0,21405468 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,18408935 0,21391971 ! covalent chromatin modification GO:0016569 29 29 0,000 0,18408935 0,21378492 ! adult behavior GO:0030534 30 29 0,000 0,18408935 0,21365029 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,18408935 0,21351584 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,18408935 0,21338155 ! transition metal ion transport GO:0000041 31 30 0,000 0,18980584 0,21986937 ! RNA catabolic process GO:0006401 30 30 0,000 0,18980584 0,21973126 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,18980584 0,21959332 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,18980584 0,21945556 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,18980584 0,21931797 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,18980584 0,21918056 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,18980584 0,21904331 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,18980584 0,21890624 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,18980584 0,21876933 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,18980584 0,2186326 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,18980584 0,21849604 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,18980584 0,21835965 ! response to temperature stimulus GO:0009266 30 30 0,000 0,18980584 0,21822343 ! regulation of ossification GO:0030278 30 30 0,000 0,18980584 0,21808739 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,18980584 0,21795151 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,18980584 0,21781579 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,18980584 0,21768025 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,18980584 0,21754488 ! regulation of translational initiation GO:0006446 31 31 0,000 0,19548311 0,2239126 ! membrane fusion GO:0006944 31 31 0,000 0,19548311 0,22377353 ! B cell activation GO:0042113 31 31 0,000 0,19548311 0,22363462 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,19548311 0,22349589 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,19548311 0,22335733 ! ion transmembrane transport GO:0034220 31 31 0,000 0,19548311 0,22321895 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,19548311 0,22308073 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,19548311 0,22294269 ! digestion GO:0007586 31 31 0,000 0,19548311 0,22280481 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,19548311 0,22266711 ! regulation of heart contraction GO:0008016 31 31 0,000 0,19548311 0,22252957 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,19548311 0,22239221 ! camera-type eye development GO:0043010 31 31 0,000 0,19548311 0,22225502 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,19548311 0,22211799 ! cell redox homeostasis GO:0045454 32 32 0,000 0,20112143 0,22838373 ! glucose catabolic process GO:0006007 32 32 0,000 0,20112143 0,2282431 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,20112143 0,22810264 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,20112143 0,22796236 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,20112143 0,22782224 ! cell maturation GO:0048469 32 32 0,000 0,20112143 0,2276823 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,20112143 0,22754254 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,20112143 0,22740294 ! nuclear export GO:0051168 32 32 0,000 0,20112143 0,22726351 ! kidney development GO:0001822 32 32 0,000 0,20112143 0,22712426 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,20112143 0,22698518 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,20112143 0,22684626 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,20672104 0,2330195 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,20672104 0,23287707 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,20672104 0,23273481 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,20672104 0,23259273 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,20672104 0,23245081 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,20672104 0,23230908 ! regulation of actin filament length GO:0030832 34 34 0,000 0,21228222 0,23841325 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,21228222 0,23826805 ! ear development GO:0043583 34 34 0,000 0,21228222 0,23812303 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,21228222 0,23797819 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,21228222 0,23783352 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,21228222 0,23768903 ! secondary metabolic process GO:0019748 34 34 0,000 0,21228222 0,23754471 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,21228222 0,23740057 ! viral reproduction GO:0016032 34 34 0,000 0,21228222 0,2372566 ! detection of stimulus GO:0051606 36 34 0,000 0,21228222 0,23711281 ! acute inflammatory response GO:0002526 35 35 0,000 0,21780522 0,24313448 ! regulation of cellular component size GO:0032535 35 35 0,000 0,21780522 0,2429873 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,21780522 0,24284031 ! mesoderm development GO:0007498 35 35 0,000 0,21780522 0,24269349 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,21780522 0,24254684 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,21780522 0,24240038 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,21780522 0,24225409 ! inorganic anion transport GO:0015698 35 35 0,000 0,21780522 0,24210798 ! regulation of immune effector process GO:0002697 35 35 0,000 0,21780522 0,24196204 ! hydrogen transport GO:0006818 36 36 0,000 0,2232903 0,24790604 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2232903 0,24775679 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,2232903 0,24760771 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2232903 0,24745882 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,2232903 0,24731011 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,2232903 0,24716157 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,2232903 0,24701322 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,2232903 0,24686504 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,2232903 0,24671704 ! gonad development GO:0008406 36 36 0,000 0,2232903 0,24656922 ! regulation of lipase activity GO:0060191 36 36 0,000 0,2232903 0,24642157 ! activation of immune response GO:0002253 36 36 0,000 0,2232903 0,2462741 ! coagulation GO:0050817 39 36 0,000 0,2232903 0,24612681 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,22873771 0,25198063 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,22873771 0,2518301 GO:0090046|regulation of transcription regulator activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,22873771 0,25167976 ! eye development GO:0001654 37 37 0,000 0,22873771 0,25152959 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,22873771 0,2513796 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! adaptive immune response GO:0002250 37 37 0,000 0,22873771 0,25122979 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,2341477 0,25701859 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,2341477 0,2568656 ! hexose catabolic process GO:0019320 38 38 0,000 0,2341477 0,2567128 ! RNA elongation GO:0006354 38 38 0,000 0,2341477 0,25656017 ! regulation of neurological system process GO:0031644 38 38 0,000 0,2341477 0,25640773 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,2341477 0,25625547 ! hemostasis GO:0007599 42 39 0,000 0,23952053 0,26198002 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,23952053 0,26182464 ! response to unfolded protein GO:0006986 39 39 0,000 0,23952053 0,26166944 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,23952053 0,26151442 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,23952053 0,26135959 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,23952053 0,26120494 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,23952053 0,26105047 ! developmental maturation GO:0021700 39 39 0,000 0,23952053 0,26089618 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,23952053 0,26074208 ! limb development GO:0060173 39 39 0,000 0,23952053 0,26058816 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,23952053 0,26043442 ! DNA catabolic process GO:0006308 41 40 0,000 0,24485645 0,26607927 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,2501557 0,27167764 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,2501557 0,27151765 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,2501557 0,27135784 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,2501557 0,27119821 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,2501557 0,27103878 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,25541854 0,27657836 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,25541854 0,27641595 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,25541854 0,27625374 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,25541854 0,27609171 ! forebrain development GO:0030900 43 42 0,000 0,25541854 0,27592987 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,25541854 0,27576823 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,2606452 0,28124655 ! alcohol catabolic process GO:0046164 43 43 0,000 0,2606452 0,28108198 ! humoral immune response GO:0006959 44 44 0,000 0,26583593 0,28651206 ! mRNA transport GO:0051028 44 44 0,000 0,26583593 0,28634461 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,26583593 0,28617735 ! amine biosynthetic process GO:0009309 46 45 0,000 0,27099097 0,29155655 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,27099097 0,29138644 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,27099097 0,29121654 ! regulation of DNA binding GO:0051101 47 45 0,000 0,27099097 0,29104683 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,27099097 0,29087732 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,27099097 0,29070801 ! protein processing GO:0016485 45 45 0,000 0,27099097 0,2905389 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,27611057 0,29585569 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,27611057 0,29568378 ! tube morphogenesis GO:0035239 47 46 0,000 0,27611057 0,29551207 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,27611057 0,29534056 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,28119496 0,30060458 ! regulation of blood pressure GO:0008217 48 47 0,000 0,28119496 0,30043032 ! rhythmic process GO:0048511 47 47 0,000 0,28119496 0,30025626 ! calcium ion transport GO:0006816 48 48 0,000 0,28624437 0,30547097 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,28624437 0,3052942 ! DNA recombination GO:0006310 48 48 0,000 0,28624437 0,30511762 ! leukocyte differentiation GO:0002521 50 49 0,000 0,29125905 0,31028348 ! ossification GO:0001503 50 49 0,000 0,29125905 0,31010423 GO:0060348|bone development, ! divalent metal ion transport GO:0070838 49 49 0,000 0,29125905 0,30992519 ! response to nutrient GO:0007584 49 49 0,000 0,29125905 0,30974635 ! response to bacterium GO:0009617 50 49 0,000 0,29125905 0,30956772 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,29125905 0,30938929 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,29125905 0,30921107 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,29623922 0,31431714 ! chromatin assembly GO:0031497 50 50 0,000 0,29623922 0,31413629 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,29623922 0,31395565 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,29623922 0,31377522 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,29623922 0,31359499 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,29623922 0,31341497 ! transcription initiation GO:0006352 50 50 0,000 0,29623922 0,31323516 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,29623922 0,31305555 ! positive regulation of immune response GO:0050778 51 51 0,000 0,30118512 0,31809982 ! rRNA metabolic process GO:0016072 51 51 0,000 0,30118512 0,31791763 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,30118512 0,31773565 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,30118512 0,31755388 ! protein maturation GO:0051604 51 51 0,000 0,30118512 0,31737232 ! RNA localization GO:0006403 52 52 0,000 0,30609699 0,32236385 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,30609699 0,32217975 ! cell fate commitment GO:0045165 52 52 0,000 0,30609699 0,32199586 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,30609699 0,32181218 ! tRNA metabolic process GO:0006399 53 53 0,000 0,31097504 0,32675427 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,31097504 0,32656809 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,31097504 0,32638212 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,31097504 0,32619635 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,31581951 0,33108951 ! response to virus GO:0009615 54 54 0,000 0,31581951 0,33090128 ! hormone metabolic process GO:0042445 55 54 0,000 0,31581951 0,33071327 ! sulfur metabolic process GO:0006790 55 54 0,000 0,31581951 0,33052547 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,31581951 0,33033789 ! nucleosome organization GO:0034728 55 55 0,000 0,32063062 0,33517994 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,32063062 0,33498993 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,3254086 0,33978927 ! regulation of nervous system development GO:0051960 57 56 0,000 0,3254086 0,33959686 ! regulation of binding GO:0051098 60 57 0,000 0,33015368 0,34435384 ! ATP metabolic process GO:0046034 57 57 0,000 0,33015368 0,34415907 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,33015368 0,34396452 ! innate immune response GO:0045087 58 58 0,000 0,33486607 0,34867693 ! dephosphorylation GO:0016311 60 59 0,000 0,33954599 0,35335023 ! regulation of cell development GO:0060284 60 59 0,000 0,33954599 0,35315082 ! immune effector process GO:0002252 59 59 0,000 0,33954599 0,35295164 ! potassium ion transport GO:0006813 60 60 0,000 0,34419366 0,35758113 ! protein polymerization GO:0051258 65 60 0,000 0,34419366 0,35737967 ! cellular respiration GO:0045333 62 61 0,000 0,34880931 0,36196822 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,34880931 0,36176452 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,35339314 0,36631246 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,35339314 0,36610656 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,35339314 0,36590088 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,35339314 0,36569543 ! regulation of secretion GO:0051046 65 63 0,000 0,35794538 0,37019828 ! glucose metabolic process GO:0006006 63 63 0,000 0,35794538 0,36999065 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,35794538 0,36978326 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,35794538 0,36957609 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,36246622 0,3740343 ! angiogenesis GO:0001525 65 64 0,000 0,36246622 0,37382499 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,36246622 0,37361591 ! anion transport GO:0006820 65 65 0,000 0,3669559 0,37803226 ! regulation of hormone levels GO:0010817 66 65 0,000 0,3669559 0,37782107 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,37141461 0,38219828 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,37141461 0,381985 ! DNA packaging GO:0006323 66 66 0,000 0,37141461 0,38177196 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,37141461 0,38155916 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,37584257 0,38589295 ! muscle contraction GO:0006936 67 67 0,000 0,37584257 0,38567809 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,37584257 0,38546347 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,38023998 0,38975655 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,38023998 0,3895399 ! sensory perception of sound GO:0007605 71 69 0,000 0,38460705 0,39379488 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,38460705 0,39357623 ! response to nutrient levels GO:0031667 69 69 0,000 0,38460705 0,39335782 ! positive regulation of transport GO:0051050 71 70 0,000 0,38894398 0,3975728 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,38894398 0,39735242 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,39325098 0,40152995 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,39325098 0,40130762 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,39325098 0,40108554 ! muscle system process GO:0003012 72 72 0,000 0,39752826 0,40522377 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,39752826 0,40499977 ! sensory organ development GO:0007423 72 72 0,000 0,39752826 0,40477601 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,39752826 0,4045525 ! regulation of cytokine production GO:0001817 72 72 0,000 0,39752826 0,40432924 ! electron transport chain GO:0022900 75 74 0,000 0,40599442 0,41271247 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,40599442 0,41248496 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,4101837 0,4165116 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,4101837 0,41628225 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,41434405 0,42027303 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,41847566 0,42423028 ! microtubule-based movement GO:0007018 82 78 0,000 0,42257873 0,42815426 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,42257873 0,42791901 ! metal ion homeostasis GO:0055065 78 78 0,000 0,42257873 0,42768402 ! regulation of immune response GO:0050776 78 78 0,000 0,42257873 0,42744929 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,4307 0,43542518 ! lymphocyte activation GO:0046649 82 81 0,000 0,43471859 0,43924691 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,44267262 0,4470387 ! ncRNA processing GO:0034470 83 83 0,000 0,44267262 0,44679389 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,45051702 0,45446244 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,45051702 0,45421383 ! hexose metabolic process GO:0019318 87 86 0,000 0,45439858 0,45787675 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,46208132 0,46536387 ! chemotaxis GO:0006935 90 89 0,000 0,46588287 0,46893617 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,46588287 0,4686802 ! brain development GO:0007420 91 90 0,000 0,4696581 0,47222034 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,4734072 0,47573036 ! visual perception GO:0007601 93 92 0,000 0,47713035 0,47921048 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,47713035 0,47894948 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,47713035 0,47868875 ! tissue morphogenesis GO:0048729 94 93 0,000 0,48082772 0,48213574 ! pattern specification process GO:0007389 96 94 0,000 0,48449949 0,48555332 ! cofactor metabolic process GO:0051186 95 94 0,000 0,48449949 0,48528943 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,49893396 0,49947598 ! regulation of system process GO:0044057 98 98 0,000 0,49893396 0,49920482 ! response to other organism GO:0051707 101 100 0,000 0,50600203 0,50600203