pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6313-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 1,68E-06 4,041E-03 ! negative regulation of kinase activity GO:0033673 131 68 5,000 1,834E-06 2,206E-03 ! negative regulation of transferase activity GO:0051348 140 72 5,000 2,572E-06 2,063E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,654E-06 2,198E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 3,000 6,595E-06 3,174E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 7,881E-06 3,16E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 8,388E-06 2,883E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,1E-05 3,307E-03 GO:0045936|negative regulation of phosphate metabolic process, ! DNA synthesis during DNA repair GO:0000731 14 9 2,000 1,253E-05 3,35E-03 ! cell cycle arrest GO:0007050 213 100 5,000 1,734E-05 4,171E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,82E-05 3,982E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 3,123E-05 6,262E-03 ! positive regulation of cell growth GO:0030307 22 12 2,000 3,243E-05 6,003E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 3,243E-05 5,574E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell size GO:0045792 134 69 4,000 3,603E-05 5,779E-03 ! nucleus organization GO:0006997 67 38 3,000 5,163E-05 7,764E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 5,324E-05 7,535E-03 ! positive regulation of cell size GO:0045793 27 15 2,000 6,629E-05 8,86E-03 ! activation of MAPKK activity GO:0000186 35 16 2,000 8,126E-05 0,01029034 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 2,000 8,126E-05 9,776E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 8,126E-05 9,31E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of growth GO:0045926 155 84 4,000 9,276E-05 0,01014437 ! regulation of survival gene product expression GO:0045884 33 17 2,000 9,829E-05 0,01028155 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 9,829E-05 9,853E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,012E-04 9,74E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,104E-04 0,01021438 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,628E-04 0,01451001 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,66E-04 0,01426537 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,892E-04 0,01569871 ! interphase GO:0051325 213 98 4,000 1,921E-04 0,01540481 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,182E-04 0,01693767 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,552E-04 0,01918723 ! parathyroid gland development GO:0060017 13 5 1,000 2,845E-04 0,020744 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,845E-04 0,02013388 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,845E-04 0,01955863 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,845E-04 0,01901534 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,845E-04 0,01850141 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 1,000 2,845E-04 0,01801453 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 2,845E-04 0,01755262 GO:0051489|regulation of filopodium assembly, ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,845E-04 0,0171138 ! decidualization GO:0046697 11 5 1,000 2,845E-04 0,01669639 ! secretory granule organization GO:0033363 11 5 1,000 2,845E-04 0,01629886 ! stem cell division GO:0017145 11 5 1,000 2,845E-04 0,01591982 GO:0048103|somatic stem cell division, ! carnitine metabolic process GO:0009437 7 5 1,000 2,845E-04 0,015558 GO:0006577|betaine metabolic process, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 2,846E-04 0,01521467 ! vasculogenesis GO:0001570 46 25 2,000 3,221E-04 0,0168469 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 3,221E-04 0,01648846 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 3,627E-04 0,01817892 ! regulation of chromosome organization GO:0033044 42 27 2,000 4,064E-04 0,01995502 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,064E-04 0,01955592 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 1,000 4,253E-04 0,02006266 GO:0030816|positive regulation of cAMP metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 4,253E-04 0,01967684 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,253E-04 0,01930558 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 4,253E-04 0,01894807 ! carnitine transport GO:0015879 10 6 1,000 4,253E-04 0,01860356 GO:0015838|betaine transport, ! establishment of spindle localization GO:0051293 12 6 1,000 4,253E-04 0,01827135 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,253E-04 0,0179508 ! triglyceride catabolic process GO:0019433 10 6 1,000 4,253E-04 0,0176413 ! maternal placenta development GO:0001893 12 6 1,000 4,253E-04 0,0173423 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,253E-04 0,01705326 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 4,534E-04 0,0178823 ! regulation of JUN kinase activity GO:0043506 58 28 2,000 4,534E-04 0,01759387 ! cell cycle checkpoint GO:0000075 137 69 3,000 5,313E-04 0,02028872 ! urogenital system development GO:0001655 137 69 3,000 5,313E-04 0,01997171 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,575E-04 0,02063464 ! prostate gland development GO:0030850 13 7 1,000 5,933E-04 0,0216274 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 5,933E-04 0,02130461 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,933E-04 0,0209913 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,933E-04 0,02068708 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 5,933E-04 0,02039155 ! glycerol ether catabolic process GO:0044269 12 7 1,000 5,933E-04 0,02010435 GO:0046464|acylglycerol catabolic process, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,933E-04 0,01982512 ! anterograde axon cargo transport GO:0008089 18 7 1,000 5,933E-04 0,01955354 ! peptidyl-threonine modification GO:0018210 25 7 1,000 5,933E-04 0,01928931 ! triglyceride metabolic process GO:0006641 43 31 2,000 6,148E-04 0,01972153 ! regulation of caspase activity GO:0043281 122 72 3,000 6,244E-04 0,01976597 ! spindle organization GO:0007051 46 32 2,000 6,757E-04 0,02111308 ! exocytosis GO:0006887 133 74 3,000 6,925E-04 0,0213614 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 6,925E-04 0,021091 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 1,000 7,882E-04 0,02370606 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 7,882E-04 0,02341339 ! neutral lipid catabolic process GO:0046461 13 8 1,000 7,882E-04 0,02312786 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,882E-04 0,02284921 ! glycerolipid catabolic process GO:0046503 13 8 1,000 7,882E-04 0,0225772 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 7,882E-04 0,02231158 GO:0006559|L-phenylalanine catabolic process, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,882E-04 0,02205215 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 7,882E-04 0,02179867 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,882E-04 0,02155096 ! intracellular lipid transport GO:0032365 13 8 1,000 7,882E-04 0,02130882 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 7,882E-04 0,02107205 ! neutral lipid metabolic process GO:0006638 50 35 2,000 8,811E-04 0,02329684 GO:0006639|acylglycerol metabolic process, ! regulation of peptidase activity GO:0052547 134 79 3,000 8,857E-04 0,02316248 ! mitotic sister chromatid segregation GO:0000070 57 36 2,000 9,575E-04 0,02477047 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 9,575E-04 0,02450696 ! negative regulation of cell activation GO:0050866 65 36 2,000 9,575E-04 0,02424899 ! artery development GO:0060840 24 9 1,000 1,01E-03 0,02530961 GO:0048844|artery morphogenesis, ! keratinocyte proliferation GO:0043616 14 9 1,000 1,01E-03 0,02504869 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,01E-03 0,02479309 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,01E-03 0,02454265 ! motor axon guidance GO:0008045 16 9 1,000 1,01E-03 0,02429723 ! S phase GO:0051320 9 9 1,000 1,01E-03 0,02405666 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,01E-03 0,02382081 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,01E-03 0,02358954 ! sister chromatid segregation GO:0000819 58 37 2,000 1,038E-03 0,02401029 ! glycerol ether metabolic process GO:0006662 53 37 2,000 1,038E-03 0,02378162 ! ear morphogenesis GO:0042471 60 39 2,000 1,211E-03 0,02749065 ! organic ether metabolic process GO:0018904 55 39 2,000 1,211E-03 0,02723373 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,211E-03 0,02698156 ! mitochondrion organization GO:0007005 148 86 3,000 1,216E-03 0,02683876 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,258E-03 0,02751298 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,258E-03 0,02726511 ! phospholipid efflux GO:0033700 16 10 1,000 1,258E-03 0,02702167 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,258E-03 0,02678254 ! reverse cholesterol transport GO:0043691 16 10 1,000 1,258E-03 0,02654761 ! phagocytosis, engulfment GO:0006911 28 10 1,000 1,258E-03 0,02631676 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,258E-03 0,02608989 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 1,258E-03 0,0258669 ! quaternary ammonium group transport GO:0015697 21 10 1,000 1,258E-03 0,02564769 ! blastocyst formation GO:0001825 17 10 1,000 1,258E-03 0,02543216 ! cytokinesis GO:0000910 72 40 2,000 1,304E-03 0,02614928 ! gland development GO:0048732 206 88 3,000 1,324E-03 0,02632944 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,381E-03 0,02722923 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,402E-03 0,02741754 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,402E-03 0,02719644 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,439E-03 0,02769661 ! sex differentiation GO:0007548 145 90 3,000 1,439E-03 0,0274768 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,532E-03 0,02902291 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,532E-03 0,02879617 GO:0010812|negative regulation of cell-substrate adhesion, ! thymus development GO:0048538 27 11 1,000 1,532E-03 0,02857294 ! cholesterol efflux GO:0033344 19 11 1,000 1,532E-03 0,02835315 ! germ cell migration GO:0008354 25 11 1,000 1,532E-03 0,02813671 ! regulation of embryonic development GO:0045995 27 11 1,000 1,532E-03 0,02792355 ! epithelial cell differentiation GO:0030855 79 43 2,000 1,61E-03 0,02912468 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,624E-03 0,02915723 ! male sex differentiation GO:0046661 76 44 2,000 1,721E-03 0,03067196 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,832E-03 0,03240797 ! regulation of cell projection assembly GO:0060491 30 12 1,000 1,832E-03 0,03217142 ! drug transport GO:0015893 16 12 1,000 1,832E-03 0,03193829 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 1,832E-03 0,03170852 ! tyrosine metabolic process GO:0006570 16 12 1,000 1,832E-03 0,03148203 ! focal adhesion formation GO:0048041 35 12 1,000 1,832E-03 0,03125875 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 1,832E-03 0,03103862 ! cell growth GO:0016049 84 45 2,000 1,837E-03 0,03090271 ! pigmentation GO:0043473 100 46 2,000 1,957E-03 0,03270046 ! JNK cascade GO:0007254 91 47 2,000 2,082E-03 0,03455322 ! regulation of JNK cascade GO:0046328 94 47 2,000 2,082E-03 0,03431655 ! embryonic placenta development GO:0001892 23 13 1,000 2,157E-03 0,03530934 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,213E-03 0,03596821 ! cellular component disassembly GO:0022411 86 48 2,000 2,213E-03 0,03572682 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 2,213E-03 0,03548864 ! activation of caspase activity GO:0006919 84 48 2,000 2,213E-03 0,03525361 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,213E-03 0,03502168 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,213E-03 0,03479278 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 2,348E-03 0,03667701 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,488E-03 0,03861458 ! palate development GO:0060021 31 14 1,000 2,508E-03 0,03868078 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,508E-03 0,03843441 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,508E-03 0,03819115 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,508E-03 0,03795096 ! bone mineralization GO:0030282 17 14 1,000 2,508E-03 0,03771376 ! cofactor transport GO:0051181 26 14 1,000 2,508E-03 0,03747952 ! male genitalia development GO:0030539 24 14 1,000 2,508E-03 0,03724816 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,633E-03 0,03886163 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 2,000 2,783E-03 0,04082903 ! positive regulation of growth GO:0045927 90 52 2,000 2,783E-03 0,04058159 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,884E-03 0,04179521 ! response to UV GO:0009411 104 53 2,000 2,938E-03 0,04233503 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,265E-03 0,04676128 GO:0010952|positive regulation of peptidase activity, ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,284E-03 0,04675276 ! axon cargo transport GO:0008088 43 16 1,000 3,284E-03 0,04647775 ! neuron recognition GO:0008038 35 16 1,000 3,284E-03 0,04620595 ! biomineral formation GO:0031214 20 16 1,000 3,284E-03 0,04593731 ! nucleotide-excision repair GO:0006289 83 56 2,000 3,436E-03 0,04779258 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,709E-03 0,05128266 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 3,709E-03 0,05098962 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,709E-03 0,0506999 ! genitalia development GO:0048806 30 17 1,000 3,709E-03 0,05041346 ! organic cation transport GO:0015695 31 17 1,000 3,709E-03 0,05013024 ! skeletal system morphogenesis GO:0048705 105 59 2,000 3,983E-03 0,05353812 ! DNA catabolic process GO:0006308 86 59 2,000 3,983E-03 0,05324068 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,158E-03 0,05526657 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,158E-03 0,05496291 ! vitamin transport GO:0051180 27 18 1,000 4,158E-03 0,05466256 ! aromatic compound catabolic process GO:0019439 27 18 1,000 4,158E-03 0,05436549 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 4,176E-03 0,0543152 ! kidney development GO:0001822 122 60 2,000 4,176E-03 0,05402318 ! ear development GO:0043583 103 62 2,000 4,58E-03 0,05892444 ! protein secretion GO:0009306 39 19 1,000 4,63E-03 0,05925941 ! skin development GO:0043588 36 19 1,000 4,63E-03 0,05894587 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,63E-03 0,05863563 ! pigmentation during development GO:0048066 41 19 1,000 4,63E-03 0,05832864 ! actin filament bundle formation GO:0051017 42 19 1,000 4,63E-03 0,05802484 ! neuromuscular junction development GO:0007528 34 19 1,000 4,63E-03 0,0577242 ! G1 phase GO:0051318 40 19 1,000 4,63E-03 0,05742665 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,63E-03 0,05713215 ! regulation of mitosis GO:0007088 105 63 2,000 4,79E-03 0,0587993 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,79E-03 0,05850083 ! positive regulation of cell motion GO:0051272 146 64 2,000 5,006E-03 0,06082968 ! response to alkaloid GO:0043279 38 20 1,000 5,127E-03 0,06198544 ! body fluid secretion GO:0007589 31 20 1,000 5,127E-03 0,06167552 ! peptide secretion GO:0002790 35 20 1,000 5,127E-03 0,06136867 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 5,127E-03 0,06106487 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,127E-03 0,06076406 ! negative regulation of translation GO:0017148 29 20 1,000 5,127E-03 0,06046619 ! extracellular matrix organization GO:0030198 133 66 2,000 5,455E-03 0,06402623 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 5,647E-03 0,06594958 ! collagen fibril organization GO:0030199 59 21 1,000 5,647E-03 0,06563098 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 5,647E-03 0,06531545 ! response to cytokine stimulus GO:0034097 63 21 1,000 5,647E-03 0,06500293 ! regulation of cellular response to stress GO:0080135 128 67 2,000 5,689E-03 0,06517649 ! chromosome segregation GO:0007059 113 67 2,000 5,689E-03 0,06486759 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 5,928E-03 0,06727815 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,189E-03 0,06991393 ! microtubule-based transport GO:0010970 54 22 1,000 6,189E-03 0,06958723 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 6,189E-03 0,06926357 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,189E-03 0,0689429 ! lysosome organization GO:0007040 41 22 1,000 6,189E-03 0,06862519 ! central nervous system neuron development GO:0021954 46 22 1,000 6,189E-03 0,0683104 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,189E-03 0,06799848 ! activation of JUN kinase activity GO:0007257 42 22 1,000 6,189E-03 0,0676894 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 6,189E-03 0,06738311 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,189E-03 0,06707958 ! reproductive structure development GO:0048608 113 71 2,000 6,682E-03 0,07209378 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 6,682E-03 0,07177193 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,755E-03 0,07223396 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,755E-03 0,07191434 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 6,755E-03 0,07159754 ! gluconeogenesis GO:0006094 33 23 1,000 6,755E-03 0,07128351 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,755E-03 0,07097223 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 6,755E-03 0,07066365 ! axon guidance GO:0007411 139 73 2,000 7,215E-03 0,0751469 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 7,343E-03 0,07615479 ! vacuole organization GO:0007033 43 24 1,000 7,343E-03 0,07582795 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 7,343E-03 0,0755039 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 7,343E-03 0,0751826 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 7,772E-03 0,07923683 ! myelination GO:0042552 45 25 1,000 7,954E-03 0,08074626 ! telomere organization GO:0032200 43 25 1,000 7,954E-03 0,08040699 GO:0000723|telomere maintenance, ! development of primary sexual characteristics GO:0045137 124 76 2,000 8,06E-03 0,08114086 ! pyruvate metabolic process GO:0006090 38 26 1,000 8,586E-03 0,0860787 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 8,586E-03 0,08572152 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 8,586E-03 0,0853673 ! positive regulation of nuclear division GO:0051785 40 26 1,000 8,586E-03 0,085016 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 8,586E-03 0,08466757 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 8,586E-03 0,08432199 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 8,655E-03 0,08464695 ! activation of protein kinase activity GO:0032147 147 79 2,000 8,961E-03 0,0872915 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 8,961E-03 0,08693952 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 9,241E-03 0,08929066 ! neuron fate commitment GO:0048663 48 27 1,000 9,241E-03 0,0889335 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 9,241E-03 0,08857918 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 9,241E-03 0,08822768 ! male gonad development GO:0008584 44 27 1,000 9,241E-03 0,08787895 ! base-excision repair GO:0006284 41 27 1,000 9,241E-03 0,08753297 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 9,241E-03 0,0871897 ! cellular lipid catabolic process GO:0044242 134 80 2,000 9,274E-03 0,0871641 ! negative regulation of protein modification process GO:0031400 60 28 1,000 9,917E-03 0,0928394 ! lipid oxidation GO:0034440 43 28 1,000 9,917E-03 0,09247955 GO:0019395|fatty acid oxidation, ! response to drug GO:0042493 143 82 2,000 9,919E-03 0,09214573 ! regulation of ligase activity GO:0051340 142 84 2,000 0,0105897 0,09799546 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01061402 0,09784422 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01061402 0,09747077 ! tissue homeostasis GO:0001894 48 29 1,000 0,01061402 0,09710016 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 78 30 1,000 0,01133235 0,10327892 ! phospholipid transport GO:0015914 51 30 1,000 0,01133235 0,10288918 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01133235 0,10250238 GO:0008366|axon ensheathment, ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01133235 0,10211848 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01133235 0,10173744 ! response to heat GO:0009408 50 30 1,000 0,01133235 0,10135923 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01164355 0,10375697 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01207149 0,10717348 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01207149 0,10677946 GO:0055092|sterol homeostasis, ! peptide transport GO:0015833 55 31 1,000 0,01207149 0,10638833 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01207149 0,10600005 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01207149 0,1056146 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,01207149 0,10523194 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01207149 0,10485204 GO:0043433|negative regulation of transcription factor activity, ! cholesterol transport GO:0030301 56 32 1,000 0,01283121 0,11105001 ! metanephros development GO:0001656 74 32 1,000 0,01283121 0,11065198 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01283121 0,11025679 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01283121 0,10986442 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01283121 0,10947483 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01283121 0,10908799 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01283121 0,10870388 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01283121 0,10832246 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01361127 0,11450601 ! post-embryonic development GO:0009791 69 33 1,000 0,01361127 0,11410703 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01361127 0,11371083 ! sterol transport GO:0015918 57 33 1,000 0,01361127 0,11331736 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01361127 0,11292661 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01433006 0,11848152 ! glial cell differentiation GO:0010001 63 34 1,000 0,01441143 0,1187462 ! mismatch repair GO:0006298 46 34 1,000 0,01441143 0,11834093 ! placenta development GO:0001890 53 34 1,000 0,01441143 0,11793841 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01523144 0,12422662 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01523144 0,12380694 ! odontogenesis GO:0042476 66 35 1,000 0,01523144 0,12339008 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01523144 0,12297602 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01523144 0,12256473 ! cytokine production GO:0001816 59 35 1,000 0,01523144 0,12215618 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01557994 0,12453601 ! carboxylic acid catabolic process GO:0046395 156 98 2,000 0,0160098 0,12754826 GO:0016054|organic acid catabolic process, ! cell junction organization GO:0034330 86 36 1,000 0,01607109 0,127614 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01607109 0,12719422 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01607109 0,12677719 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01607109 0,12636288 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01607109 0,12595128 ! meiosis I GO:0007127 65 37 1,000 0,01693013 0,13225291 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01693013 0,13182491 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 1,000 0,01693013 0,13139967 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 1,000 0,01693013 0,13097716 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01693013 0,13055736 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01780834 0,13689095 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01780834 0,13645499 ! lipid homeostasis GO:0055088 67 38 1,000 0,01780834 0,1360218 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01780834 0,13559135 ! mammary gland development GO:0030879 86 39 1,000 0,01870549 0,14197287 ! learning GO:0007612 77 39 1,000 0,01870549 0,14152641 ! ion transmembrane transport GO:0034220 66 39 1,000 0,01870549 0,14108276 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01870549 0,14064187 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,01870549 0,14020374 ! negative regulation of binding GO:0051100 72 40 1,000 0,01962134 0,14661165 ! maintenance of protein location GO:0045185 91 40 1,000 0,01962134 0,14615774 ! gliogenesis GO:0042063 88 41 1,000 0,02055569 0,152645 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02055569 0,15217533 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02055569 0,15170853 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02150829 0,15825368 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02150829 0,1577712 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02150829 0,15729165 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02150829 0,15681501 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02247894 0,16339679 ! glucose transport GO:0015758 65 43 1,000 0,02247894 0,16290463 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02247894 0,16241543 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,02247894 0,16192916 ! phagocytosis GO:0006909 90 43 1,000 0,02247894 0,16144579 ! hexose transport GO:0008645 67 44 1,000 0,02346742 0,16804347 GO:0015749|monosaccharide transport, ! maintenance of location in cell GO:0051651 97 44 1,000 0,02346742 0,16754483 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,0244735 0,17421075 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02549697 0,18096079 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02549697 0,18042855 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02549697 0,17989943 ! response to insulin stimulus GO:0032868 95 46 1,000 0,02549697 0,17937341 ! endosome transport GO:0016197 108 47 1,000 0,02653762 0,18615016 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02660907 0,18610879 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02660907 0,18556934 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02660907 0,18503302 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02660907 0,18449978 ! neuron fate determination GO:0048664 7 5 0,000 0,02660907 0,18396961 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02660907 0,18344248 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02660907 0,18291835 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02660907 0,18239722 ! polyol transport GO:0015791 12 5 0,000 0,02660907 0,18187905 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02660907 0,18136381 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02660907 0,18085148 ! response to superoxide GO:0000303 10 5 0,000 0,02660907 0,18034204 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02660907 0,17983546 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02660907 0,17933172 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02660907 0,17883079 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02660907 0,17833266 ! female meiosis GO:0007143 7 5 0,000 0,02660907 0,17783729 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02660907 0,17734466 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02660907 0,17685476 ! cobalt ion transport GO:0006824 11 5 0,000 0,02660907 0,17636756 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02660907 0,17588303 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02660907 0,17540116 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02660907 0,17492192 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02660907 0,1744453 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02660907 0,17397126 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02660907 0,17349979 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02660907 0,17303088 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02660907 0,17256448 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02660907 0,1721006 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02660907 0,17163921 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02660907 0,17118028 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02660907 0,1707238 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02660907 0,17026974 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02660907 0,1698181 ! negative chemotaxis GO:0050919 14 5 0,000 0,02660907 0,16936885 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02660907 0,16892196 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02660907 0,16847743 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02660907 0,16803523 ! behavioral response to pain GO:0048266 9 5 0,000 0,02660907 0,16759535 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02660907 0,16715776 ! Notch receptor processing GO:0007220 8 5 0,000 0,02660907 0,16672246 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02660907 0,16628941 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02660907 0,16585861 ! micturition GO:0060073 9 5 0,000 0,02660907 0,16543004 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02660907 0,16500367 ! copulation GO:0007620 9 5 0,000 0,02660907 0,1645795 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02660907 0,1641575 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02660907 0,16373766 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02660907 0,16331996 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02660907 0,16290439 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02660907 0,16249092 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02660907 0,16207955 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02660907 0,16167026 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02660907 0,16126303 ! grooming behavior GO:0007625 6 5 0,000 0,02660907 0,16085785 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02660907 0,1604547 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02660907 0,16005356 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02660907 0,15965442 ! response to protozoan GO:0001562 10 5 0,000 0,02660907 0,15925727 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02660907 0,15886209 ! lymph vessel development GO:0001945 10 5 0,000 0,02660907 0,15846887 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02660907 0,15807759 ! endochondral ossification GO:0001958 16 5 0,000 0,02660907 0,15768824 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02660907 0,1573008 ! anagen GO:0042640 6 5 0,000 0,02660907 0,15691525 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02660907 0,1565316 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02660907 0,15614981 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02660907 0,15576989 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02660907 0,15539181 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02660907 0,15501555 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02660907 0,15464112 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02660907 0,15426849 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02660907 0,15389765 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02660907 0,15352859 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02660907 0,1531613 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02660907 0,15279576 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02660907 0,15243196 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02660907 0,15206989 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02660907 0,15170954 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02660907 0,15135088 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02660907 0,15099392 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02660907 0,15063864 ! histidine catabolic process GO:0006548 6 5 0,000 0,02660907 0,15028503 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02660907 0,14993308 ! microvillus organization GO:0032528 7 5 0,000 0,02660907 0,14958277 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02660907 0,14923409 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02660907 0,14888703 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02660907 0,14854159 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02660907 0,14819774 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02660907 0,14785548 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02660907 0,1475148 ! polyol catabolic process GO:0046174 7 5 0,000 0,02660907 0,14717569 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02660907 0,14683813 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02660907 0,14650211 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02660907 0,14616763 ! muscle cell migration GO:0014812 8 5 0,000 0,02660907 0,14583468 ! mitochondrial fission GO:0000266 8 5 0,000 0,02660907 0,14550324 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02660907 0,1451733 ! mRNA transcription GO:0009299 9 5 0,000 0,02660907 0,14484485 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02660907 0,14451789 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02660907 0,1441924 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02660907 0,14386837 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02660907 0,14354579 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02660907 0,14322466 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02660907 0,14290496 ! response to food GO:0032094 6 5 0,000 0,02660907 0,14258669 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02660907 0,14226983 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02660907 0,14195438 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02660907 0,14164032 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02660907 0,14132765 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02660907 0,14101635 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02660907 0,14070643 ! forebrain neuron development GO:0021884 13 5 0,000 0,02660907 0,14039786 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02660907 0,14009064 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02660907 0,13978477 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02660907 0,13948023 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02660907 0,13917701 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02660907 0,13887511 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02660907 0,13857451 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02660907 0,13827521 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02660907 0,13797721 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02660907 0,13768048 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02660907 0,13738503 ! basic amino acid transport GO:0015802 11 5 0,000 0,02660907 0,13709084 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02660907 0,13679791 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02660907 0,13650623 ! depyrimidination GO:0045008 10 5 0,000 0,02660907 0,1362158 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02660907 0,13592659 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02660907 0,13563861 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02660907 0,13535185 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02660907 0,1350663 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02660907 0,13478194 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02660907 0,13449879 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02660907 0,13421682 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02660907 0,13393603 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02660907 0,13365642 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02660907 0,13337797 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02660907 0,13310067 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02660907 0,13282453 ! response to arsenic GO:0046685 10 5 0,000 0,02660907 0,13254953 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02660907 0,13227567 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02660907 0,13200294 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02660907 0,13173132 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02660907 0,13146083 ! response to cadmium ion GO:0046686 7 5 0,000 0,02660907 0,13119144 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02660907 0,13092316 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02660907 0,13065597 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02660907 0,13038987 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02660907 0,13012485 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02660907 0,1298609 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02660907 0,12959802 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02660907 0,12933621 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02660907 0,12907545 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02660907 0,12881574 ! neural tube patterning GO:0021532 7 5 0,000 0,02660907 0,12855708 ! embryonic cleavage GO:0040016 6 5 0,000 0,02660907 0,12829945 ! peroxisome fission GO:0016559 5 5 0,000 0,02660907 0,12804285 ! histone demethylation GO:0016577 10 5 0,000 0,02660907 0,12778727 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02660907 0,12753272 ! mitotic recombination GO:0006312 9 5 0,000 0,02660907 0,12727917 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02660907 0,12702663 ! metaphase plate congression GO:0051310 7 5 0,000 0,02660907 0,1267751 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02660907 0,12652455 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02660907 0,126275 ! enteric nervous system development GO:0048484 8 5 0,000 0,02660907 0,12602642 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02660907 0,12577883 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02660907 0,1255322 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02660907 0,12528654 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02660907 0,12504184 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02660907 0,1247981 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02660907 0,1245553 ! plasminogen activation GO:0031639 5 5 0,000 0,02660907 0,12431344 ! B cell homeostasis GO:0001782 13 5 0,000 0,02660907 0,12407253 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02660907 0,12383254 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02660907 0,12359348 ! metaphase GO:0051323 8 5 0,000 0,02660907 0,12335534 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02660907 0,12311812 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02660907 0,12288181 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02660907 0,12264641 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02660907 0,1224119 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02660907 0,12217829 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02660907 0,12194557 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02660907 0,12171373 ! response to redox state GO:0051775 5 5 0,000 0,02660907 0,12148278 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02660907 0,1212527 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02660907 0,12102349 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02660907 0,12079514 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02660907 0,12056765 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02660907 0,12034102 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02660907 0,12011524 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02660907 0,11989031 ! striatum development GO:0021756 9 5 0,000 0,02660907 0,11966621 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02660907 0,11944295 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02660907 0,11922053 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02660907 0,11899893 ! glial cell migration GO:0008347 11 5 0,000 0,02660907 0,11877815 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02660907 0,11855819 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02660907 0,11833905 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02660907 0,11812071 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02660907 0,11790317 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02660907 0,11768644 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02660907 0,1174705 ! neuroprotection GO:0043526 6 5 0,000 0,02660907 0,11725536 ! neural plate development GO:0001840 8 5 0,000 0,02660907 0,11704099 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02660907 0,11682742 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02660907 0,11661462 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02660907 0,11640259 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02660907 0,11619133 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02660907 0,11598084 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02660907 0,11577111 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02660907 0,11556214 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02660907 0,11535392 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02660907 0,11514645 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02660907 0,11493972 ! spindle assembly GO:0051225 6 5 0,000 0,02660907 0,11473373 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02660907 0,11452849 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02660907 0,11432397 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02660907 0,11412019 ! drug metabolic process GO:0017144 6 5 0,000 0,02660907 0,11391712 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02660907 0,11371478 ! organ regeneration GO:0031100 7 5 0,000 0,02660907 0,11351316 ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02660907 0,11331225 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02660907 0,11311206 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,0286696 0,12165618 ! regulation of action potential GO:0001508 95 49 1,000 0,0286696 0,121442 ! response to temperature stimulus GO:0009266 76 49 1,000 0,0286696 0,12122857 ! endocrine system development GO:0035270 104 49 1,000 0,0286696 0,12101588 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0286696 0,12080395 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0286696 0,12059275 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,02976051 0,12496299 ! inner ear development GO:0048839 79 50 1,000 0,02976051 0,12474529 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03086777 0,12916148 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03086777 0,12893724 ! vesicle organization GO:0016050 107 51 1,000 0,03086777 0,12871378 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03184583 0,1325624 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03184583 0,13233345 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03184583 0,13210529 ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03184583 0,13187792 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03184583 0,13165132 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03184583 0,13142551 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03184583 0,13120046 ! sleep GO:0030431 13 6 0,000 0,03184583 0,13097619 ! response to oxygen radical GO:0000305 11 6 0,000 0,03184583 0,13075268 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03184583 0,13052993 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03184583 0,13030794 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03184583 0,13008671 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03184583 0,12986622 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03184583 0,12964648 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03184583 0,12942748 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03184583 0,12920922 ! forebrain regionalization GO:0021871 8 6 0,000 0,03184583 0,1289917 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03184583 0,12877491 ! male meiosis GO:0007140 7 6 0,000 0,03184583 0,12855884 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03184583 0,1283435 ! response to zinc ion GO:0010043 9 6 0,000 0,03184583 0,12812888 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03184583 0,12791497 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03184583 0,12770178 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03184583 0,1274893 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03184583 0,12727752 ! malate metabolic process GO:0006108 11 6 0,000 0,03184583 0,12706645 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03184583 0,12685608 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03184583 0,1266464 ! protein refolding GO:0042026 15 6 0,000 0,03184583 0,12643741 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03184583 0,12622911 ! opsonization GO:0008228 8 6 0,000 0,03184583 0,1260215 ! mating behavior GO:0007617 7 6 0,000 0,03184583 0,12581456 ! neuron remodeling GO:0016322 15 6 0,000 0,03184583 0,12560831 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03184583 0,12540273 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03184583 0,12519783 ! equilibrioception GO:0050957 14 6 0,000 0,03184583 0,12499359 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03184583 0,12479002 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03184583 0,1245871 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03184583 0,12438485 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03184583 0,12418326 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03184583 0,12398231 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03184583 0,12378202 ! toxin metabolic process GO:0009404 11 6 0,000 0,03184583 0,12358237 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03184583 0,12338336 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03184583 0,123185 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03184583 0,12298727 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03184583 0,12279018 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03184583 0,12259371 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03184583 0,12239787 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03184583 0,12220266 ! thymic T cell selection GO:0045061 12 6 0,000 0,03184583 0,12200807 ! protein lipoylation GO:0009249 10 6 0,000 0,03184583 0,1218141 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03184583 0,12162075 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03184583 0,121428 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03184583 0,12123587 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03184583 0,12104434 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03184583 0,12085342 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03184583 0,1206631 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03184583 0,12047338 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03184583 0,12028425 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03184583 0,12009572 ! hyperosmotic response GO:0006972 9 6 0,000 0,03184583 0,11990778 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03184583 0,11972042 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03184583 0,11953365 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03184583 0,11934746 ! urea metabolic process GO:0019627 7 6 0,000 0,03184583 0,11916185 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03184583 0,11897682 ! neutrophil activation GO:0042119 8 6 0,000 0,03184583 0,11879236 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03184583 0,11860847 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03184583 0,11842515 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03184583 0,11824239 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03184583 0,1180602 ! neuron apoptosis GO:0051402 9 6 0,000 0,03184583 0,11787857 ! nucleoside salvage GO:0043174 9 6 0,000 0,03184583 0,1176975 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03184583 0,11751698 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03184583 0,11733701 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03184583 0,1171576 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03184583 0,11697873 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03184583 0,11680041 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03184583 0,11662263 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03184583 0,11644539 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03184583 0,11626869 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03184583 0,11609253 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03184583 0,1159169 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03184583 0,1157418 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03184583 0,11556722 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03184583 0,11539318 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03184583 0,11521965 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03184583 0,11504665 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03184583 0,11487417 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03184583 0,1147022 ! neural nucleus development GO:0048857 14 6 0,000 0,03184583 0,11453075 ! response to UV-C GO:0010225 11 6 0,000 0,03184583 0,11435981 ! astrocyte development GO:0014002 15 6 0,000 0,03184583 0,11418937 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03184583 0,11401945 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03184583 0,11385003 ! interaction with symbiont GO:0051702 13 6 0,000 0,03184583 0,11368111 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03184583 0,1135127 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03184583 0,11334478 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03184583 0,11317736 ! response to copper ion GO:0046688 10 6 0,000 0,03184583 0,11301043 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03184583 0,11284399 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03184583 0,11267804 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03184583 0,11251258 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03184583 0,11234761 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03184583 0,11218312 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03184583 0,11201911 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03184583 0,11185558 ! hair follicle maturation GO:0048820 7 6 0,000 0,03184583 0,11169252 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03184583 0,11152994 ! Schwann cell development GO:0014044 15 6 0,000 0,03184583 0,11136783 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03184583 0,1112062 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03184583 0,11104503 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03184583 0,11088433 ! subpallium development GO:0021544 10 6 0,000 0,03184583 0,11072409 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03184583 0,11056431 ! histone ubiquitination GO:0016574 8 6 0,000 0,03184583 0,110405 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03184583 0,11024614 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03184583 0,11008774 ! G2 phase GO:0051319 16 6 0,000 0,03184583 0,1099298 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03184583 0,10977231 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03184583 0,10961526 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03184583 0,10945867 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03184583 0,10930252 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03184583 0,10914682 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03184583 0,10899156 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03184583 0,10883675 ! receptor internalization GO:0031623 10 6 0,000 0,03184583 0,10868237 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03184583 0,10852843 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03184583 0,10837492 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03184583 0,10822185 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03184583 0,10806921 ! protein deubiquitination GO:0016579 14 6 0,000 0,03184583 0,107917 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03184583 0,10776522 ! protein destabilization GO:0031648 9 6 0,000 0,03184583 0,10761386 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03184583 0,10746293 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03184583 0,10731242 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03184583 0,10716233 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03184583 0,10701267 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03184583 0,10686342 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03184583 0,10671458 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03184583 0,10656616 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03184583 0,10641815 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03184583 0,10627055 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03184583 0,10612336 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03184583 0,10597658 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03184583 0,10583021 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03184583 0,10568423 ! catecholamine transport GO:0051937 9 6 0,000 0,03184583 0,10553866 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03184583 0,10539349 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03184583 0,10524872 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03184583 0,10510435 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03184583 0,10496037 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03184583 0,10481678 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03184583 0,10467359 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03184583 0,10453079 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03184583 0,10438838 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03184583 0,10424635 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03184583 0,10410471 ! synapse organization GO:0050808 85 52 1,000 0,03199116 0,10443789 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,03313048 0,10801075 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03428553 0,11162515 ! cell recognition GO:0008037 85 54 1,000 0,03428553 0,11147431 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03545611 0,1151247 ! aging GO:0007568 103 55 1,000 0,03545611 0,11496955 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03545611 0,11481481 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03664202 0,11849558 ! regulation of DNA replication GO:0006275 101 56 1,000 0,03664202 0,11833653 ! proton transport GO:0015992 94 56 1,000 0,03664202 0,1181779 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03664202 0,11801969 ! tRNA transcription GO:0009304 14 7 0,000 0,03705459 0,11918897 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03705459 0,11902983 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03705459 0,11887113 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03705459 0,11871284 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03705459 0,11855498 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03705459 0,11839754 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03705459 0,11824051 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03705459 0,1180839 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03705459 0,11792771 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03705459 0,11777192 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03705459 0,11761655 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03705459 0,11746159 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03705459 0,11730703 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03705459 0,11715289 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03705459 0,11699914 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03705459 0,1168458 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03705459 0,11669286 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03705459 0,11654032 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03705459 0,11638818 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03705459 0,11623644 ! glycolipid transport GO:0046836 10 7 0,000 0,03705459 0,11608509 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03705459 0,11593413 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03705459 0,11578357 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03705459 0,11563339 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03705459 0,11548361 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03705459 0,11533421 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03705459 0,1151852 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03705459 0,11503658 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03705459 0,11488833 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03705459 0,11474047 ! mRNA stabilization GO:0048255 18 7 0,000 0,03705459 0,11459299 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03705459 0,11444589 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03705459 0,11429916 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03705459 0,11415281 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03705459 0,11400684 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03705459 0,11386123 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03705459 0,113716 ! lipoprotein transport GO:0042953 14 7 0,000 0,03705459 0,11357114 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03705459 0,11342665 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03705459 0,11328252 ! rhythmic behavior GO:0007622 15 7 0,000 0,03705459 0,11313876 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03705459 0,11299537 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03705459 0,11285234 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03705459 0,11270967 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03705459 0,11256736 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03705459 0,11242541 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03705459 0,11228381 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03705459 0,11214257 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03705459 0,11200169 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03705459 0,11186116 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03705459 0,11172099 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03705459 0,11158116 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03705459 0,11144168 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03705459 0,11130255 ! spinal cord patterning GO:0021511 13 7 0,000 0,03705459 0,11116377 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03705459 0,11102534 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03705459 0,11088725 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03705459 0,1107495 ! adrenal gland development GO:0030325 17 7 0,000 0,03705459 0,11061209 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03705459 0,11047503 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03705459 0,1103383 ! ovulation GO:0030728 9 7 0,000 0,03705459 0,11020191 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03705459 0,11006586 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03705459 0,10993014 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03705459 0,10979476 ! microtubule nucleation GO:0007020 20 7 0,000 0,03705459 0,10965971 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03705459 0,109525 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03705459 0,10939061 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03705459 0,10925655 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03705459 0,10912282 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03705459 0,10898942 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03705459 0,10885634 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03705459 0,10872359 ! galactose metabolic process GO:0006012 13 7 0,000 0,03705459 0,10859116 ! vesicle fusion GO:0006906 17 7 0,000 0,03705459 0,10845906 ! response to dietary excess GO:0002021 8 7 0,000 0,03705459 0,10832727 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03705459 0,10819581 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,03705459 0,10806466 ! organ growth GO:0035265 15 7 0,000 0,03705459 0,10793383 ! purine salvage GO:0043101 10 7 0,000 0,03705459 0,10780332 ! nucleoside transport GO:0015858 8 7 0,000 0,03705459 0,10767312 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03705459 0,10754324 ! parturition GO:0007567 14 7 0,000 0,03705459 0,10741367 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03705459 0,10728441 ! rRNA modification GO:0000154 14 7 0,000 0,03705459 0,10715546 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03705459 0,10702683 ! spindle checkpoint GO:0031577 15 7 0,000 0,03705459 0,1068985 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03705459 0,10677047 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03705459 0,10664276 ! macrophage differentiation GO:0030225 11 7 0,000 0,03705459 0,10651535 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03705459 0,10638824 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03705459 0,10626144 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03705459 0,10613494 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03705459 0,10600874 ! fibrinolysis GO:0042730 10 7 0,000 0,03705459 0,10588283 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03705459 0,10575723 ! eating behavior GO:0042755 7 7 0,000 0,03705459 0,10563193 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03705459 0,10550692 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03705459 0,10538221 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03705459 0,10525779 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03705459 0,10513366 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03705459 0,10500983 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03705459 0,10488629 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03705459 0,10476304 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03705459 0,10464008 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03705459 0,1045174 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03705459 0,10439502 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03705459 0,10427292 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03705459 0,10415111 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03705459 0,10402958 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03705459 0,10390833 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03705459 0,10378736 ! regulation of meiosis GO:0040020 12 7 0,000 0,03705459 0,10366668 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03705459 0,10354628 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03705459 0,10342616 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03705459 0,10330631 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03705459 0,10318674 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03705459 0,10306745 ! transcription termination GO:0006353 13 7 0,000 0,03705459 0,10294844 ! response to tumor cell GO:0002347 13 7 0,000 0,03705459 0,1028297 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03705459 0,10271123 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03705459 0,10259303 ! anaphase GO:0051322 17 7 0,000 0,03705459 0,10247511 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03705459 0,10235746 ! axonal fasciculation GO:0007413 18 7 0,000 0,03705459 0,10224008 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03705459 0,10212296 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03705459 0,10200612 ! diuresis GO:0030146 12 7 0,000 0,03705459 0,10188954 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03705459 0,10177323 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03705459 0,10165718 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03705459 0,1015414 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03705459 0,10142588 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03705459 0,10131062 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03705459 0,10119563 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03705459 0,10108089 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03705459 0,10096642 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03705459 0,1008522 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03705459 0,10073824 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03705459 0,10062454 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03705459 0,1005111 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03705459 0,10039791 ! lymph node development GO:0048535 10 7 0,000 0,03705459 0,10028498 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03705459 0,1001723 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03705459 0,10005987 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03705459 0,0999477 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03705459 0,09983577 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03705459 0,0997241 ! adult feeding behavior GO:0008343 9 7 0,000 0,03705459 0,09961268 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03705459 0,0995015 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03705459 0,09939058 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03705459 0,0992799 ! muscle adaptation GO:0043500 14 7 0,000 0,03705459 0,09916946 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03705459 0,09905927 ! retina homeostasis GO:0001895 12 7 0,000 0,03705459 0,09894933 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03705459 0,09883963 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03705459 0,09873017 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03705459 0,09862096 ! protein prenylation GO:0018342 18 7 0,000 0,03705459 0,09851198 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03705459 0,09840325 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03705459 0,09829476 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03705459 0,0981865 ! muscle fiber development GO:0048747 112 57 1,000 0,03784307 0,10016549 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,03784307 0,10005542 ! lipid modification GO:0030258 97 57 1,000 0,03784307 0,09994559 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,03784307 0,099836 ! maintenance of location GO:0051235 118 57 1,000 0,03784307 0,09972665 ! hydrogen transport GO:0006818 97 58 1,000 0,03905906 0,10281849 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,0402898 0,10594235 ! establishment of organelle localization GO:0051656 109 59 1,000 0,0402898 0,1058267 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,04153509 0,10897865 ! camera-type eye development GO:0043010 116 60 1,000 0,04153509 0,10885994 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0422355 0,1105752 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0422355 0,11045501 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0422355 0,11033508 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0422355 0,11021541 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0422355 0,110096 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0422355 0,10997685 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0422355 0,10985796 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0422355 0,10973932 ! meiotic prophase I GO:0007128 13 8 0,000 0,0422355 0,10962094 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0422355 0,10950281 ! oligopeptide transport GO:0006857 15 8 0,000 0,0422355 0,10938494 ! UTP metabolic process GO:0046051 8 8 0,000 0,0422355 0,10926732 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0422355 0,10914996 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0422355 0,10903285 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0422355 0,10891598 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0422355 0,10879937 ! succinate metabolic process GO:0006105 14 8 0,000 0,0422355 0,10868301 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0422355 0,10856689 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0422355 0,10845103 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0422355 0,10833541 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0422355 0,10822003 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0422355 0,10810491 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0422355 0,10799002 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0422355 0,10787538 ! reflex GO:0060004 16 8 0,000 0,0422355 0,10776099 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0422355 0,10764683 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0422355 0,10753292 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0422355 0,10741925 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0422355 0,10730582 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0422355 0,10719263 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0422355 0,10707968 ! pigment granule organization GO:0048753 16 8 0,000 0,0422355 0,10696696 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0422355 0,10685448 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0422355 0,10674224 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0422355 0,10663023 ! histidine metabolic process GO:0006547 16 8 0,000 0,0422355 0,10651846 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0422355 0,10640692 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0422355 0,10629562 ! glycine catabolic process GO:0006546 13 8 0,000 0,0422355 0,10618455 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0422355 0,10607371 ! ER overload response GO:0006983 12 8 0,000 0,0422355 0,1059631 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0422355 0,10585272 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0422355 0,10574257 ! melanin metabolic process GO:0006582 15 8 0,000 0,0422355 0,10563265 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0422355 0,10552296 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0422355 0,1054135 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0422355 0,10530426 ! macrophage activation GO:0042116 12 8 0,000 0,0422355 0,10519525 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0422355 0,10508647 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0422355 0,10497791 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0422355 0,10486957 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0422355 0,10476146 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0422355 0,10465357 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0422355 0,1045459 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0422355 0,10443845 ! osteoblast development GO:0002076 16 8 0,000 0,0422355 0,10433122 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0422355 0,10422422 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0422355 0,10411743 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0422355 0,10401086 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0422355 0,10390451 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0422355 0,10379838 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0422355 0,10369246 ! response to UV-B GO:0010224 16 8 0,000 0,0422355 0,10358676 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0422355 0,10348128 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0422355 0,103376 ! intermediate filament organization GO:0045109 12 8 0,000 0,0422355 0,10327095 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0422355 0,1031661 ! cellular extravasation GO:0045123 12 8 0,000 0,0422355 0,10306147 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0422355 0,10295705 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0422355 0,10285285 ! response to antibiotic GO:0046677 11 8 0,000 0,0422355 0,10274885 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0422355 0,10264506 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0422355 0,10254149 ! DNA topological change GO:0006265 12 8 0,000 0,0422355 0,10243812 ! response to tropane GO:0014073 15 8 0,000 0,0422355 0,10233496 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0422355 0,102232 ! melanosome transport GO:0032402 13 8 0,000 0,0422355 0,10212926 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0422355 0,10202672 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0422355 0,10192439 ! mast cell activation GO:0045576 14 8 0,000 0,0422355 0,10182226 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0422355 0,10172033 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0422355 0,10161861 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0422355 0,1015171 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0422355 0,10141578 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0422355 0,10131467 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0422355 0,10121376 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0422355 0,10111305 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0422355 0,10101254 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0422355 0,10091223 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0422355 0,10081212 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0422355 0,1007122 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0422355 0,10061249 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0422355 0,10051297 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0422355 0,10041365 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0422355 0,10031452 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0422355 0,10021559 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0422355 0,10011686 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0422355 0,10001832 ! hormone catabolic process GO:0042447 17 8 0,000 0,0422355 0,09991997 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0422355 0,09982182 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0422355 0,09972386 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0422355 0,09962609 ! ATP catabolic process GO:0006200 11 8 0,000 0,0422355 0,09952851 ! blastocyst growth GO:0001832 19 8 0,000 0,0422355 0,09943113 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0422355 0,09933393 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0422355 0,09923693 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0422355 0,09914011 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0422355 0,09904348 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0422355 0,09894704 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0422355 0,09885079 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0422355 0,09875473 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0422355 0,09865885 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0422355 0,09856315 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0422355 0,09846765 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0422355 0,09837233 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0422355 0,09827719 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0422355 0,09818223 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0422355 0,09808746 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0422355 0,09799288 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0422355 0,09789847 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,04279475 0,09909928 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,04406858 0,10195096 ! gonad development GO:0008406 98 62 1,000 0,04406858 0,10185303 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04406858 0,10175528 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,0453564 0,10462848 ! detection of external stimulus GO:0009581 91 63 1,000 0,0453564 0,10452826 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,0453564 0,10442823 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,04665803 0,10732239 GO:0048609|reproductive process in a multicellular organism, ! regulation of developmental growth GO:0048638 15 9 0,000 0,0473887 0,10889897 ! axon extension GO:0048675 15 9 0,000 0,0473887 0,10879506 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0473887 0,10869135 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0473887 0,10858783 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0473887 0,10848451 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0473887 0,10838139 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0473887 0,10827846 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0473887 0,10817573 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0473887 0,1080732 ! phosphate transport GO:0006817 19 9 0,000 0,0473887 0,10797086 ! reproductive behavior GO:0019098 19 9 0,000 0,0473887 0,10786871 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0473887 0,10776675 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0473887 0,10766499 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0473887 0,10756342 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0473887 0,10746204 ! GTP metabolic process GO:0046039 9 9 0,000 0,0473887 0,10736085 ! RNA methylation GO:0001510 15 9 0,000 0,0473887 0,10725985 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0473887 0,10715904 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0473887 0,10705843 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0473887 0,106958 ! regulation of histone modification GO:0031056 12 9 0,000 0,0473887 0,10685775 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0473887 0,1067577 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0473887 0,10665783 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0473887 0,10655815 ! chemosensory behavior GO:0007635 20 9 0,000 0,0473887 0,10645866 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0473887 0,10635935 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0473887 0,10626023 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0473887 0,10616129 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0473887 0,10606253 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0473887 0,10596396 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0473887 0,10586557 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0473887 0,10576737 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0473887 0,10566935 ! protein targeting to ER GO:0045047 22 9 0,000 0,0473887 0,1055715 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0473887 0,10547384 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0473887 0,10537636 ! T cell selection GO:0045058 23 9 0,000 0,0473887 0,10527906 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,0473887 0,10518194 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0473887 0,105085 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0473887 0,10498824 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0473887 0,10489165 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0473887 0,10479524 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0473887 0,10469901 ! mannose metabolic process GO:0006013 13 9 0,000 0,0473887 0,10460296 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0473887 0,10450708 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0473887 0,10441138 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0473887 0,10431585 ! receptor clustering GO:0043113 18 9 0,000 0,0473887 0,1042205 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0473887 0,10412532 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0473887 0,10403031 ! ruffle organization GO:0031529 15 9 0,000 0,0473887 0,10393548 ! retinol metabolic process GO:0042572 18 9 0,000 0,0473887 0,10384082 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0473887 0,10374634 ! behavioral fear response GO:0001662 22 9 0,000 0,0473887 0,10365202 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0473887 0,10355788 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0473887 0,10346391 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0473887 0,1033701 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,0473887 0,10327647 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0473887 0,10318301 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0473887 0,10308971 ! segment specification GO:0007379 13 9 0,000 0,0473887 0,10299659 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0473887 0,10290363 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0473887 0,10281084 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0473887 0,10271822 ! response to amine stimulus GO:0014075 13 9 0,000 0,0473887 0,10262576 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0473887 0,10253347 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0473887 0,10244135 ! erythrocyte development GO:0048821 15 9 0,000 0,0473887 0,10234939 ! gas homeostasis GO:0033483 16 9 0,000 0,0473887 0,1022576 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0473887 0,10216597 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0473887 0,10207451 ! renal water homeostasis GO:0003091 14 9 0,000 0,0473887 0,10198321 ! postreplication repair GO:0006301 22 9 0,000 0,0473887 0,10189207 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0473887 0,10180109 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0473887 0,10171028 ! icosanoid secretion GO:0032309 15 9 0,000 0,0473887 0,10161963 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0473887 0,10152914 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0473887 0,10143881 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0473887 0,10134864 ! regulation of cell division GO:0051302 15 9 0,000 0,0473887 0,10125864 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0473887 0,10116879 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0473887 0,1010791 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0473887 0,10098957 ! sterol catabolic process GO:0016127 11 9 0,000 0,0473887 0,1009002 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0473887 0,10081098 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0473887 0,10072193 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0473887 0,10063303 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0473887 0,10054429 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0473887 0,1004557 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0473887 0,10036727 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0473887 0,100279 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0473887 0,10019088 ! purine base metabolic process GO:0006144 21 9 0,000 0,0473887 0,10010292 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0473887 0,10001511 ! pigment granule transport GO:0051904 17 9 0,000 0,0473887 0,09992745 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0473887 0,09983995 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0473887 0,0997526 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0473887 0,09966541 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0473887 0,09957836 ! mitochondrion localization GO:0051646 15 9 0,000 0,0473887 0,09949147 ! germ cell development GO:0007281 118 65 1,000 0,04797328 0,10063096 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,04797328 0,1005433 ! actin filament organization GO:0007015 148 66 1,000 0,04930197 0,10323806 ! activation of MAPK activity GO:0000187 115 67 1,000 0,05064391 0,10595587 ! lung development GO:0030324 144 67 1,000 0,05064391 0,10586382 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,05064391 0,10577192 ! amino acid transport GO:0006865 125 68 1,000 0,05199894 0,10850776 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,05199894 0,10841373 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,05199894 0,10831986 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05251435 0,1092989 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05251435 0,10920444 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05251435 0,10911013 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05251435 0,10901599 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05251435 0,10892201 ! synapsis GO:0007129 13 10 0,000 0,05251435 0,10882819 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05251435 0,10873454 ! N-glycan processing GO:0006491 20 10 0,000 0,05251435 0,10864104 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05251435 0,10854771 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05251435 0,10845454 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05251435 0,10836152 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05251435 0,10826867 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05251435 0,10817597 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05251435 0,10808343 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05251435 0,10799105 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05251435 0,10789883 ! androgen metabolic process GO:0008209 17 10 0,000 0,05251435 0,10780677 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05251435 0,10771486 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05251435 0,10762311 ! lung alveolus development GO:0048286 26 10 0,000 0,05251435 0,10753152 ! pathogenesis GO:0009405 13 10 0,000 0,05251435 0,10744008 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05251435 0,1073488 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05251435 0,10725767 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05251435 0,1071667 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05251435 0,10707588 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05251435 0,10698521 ! endoderm development GO:0007492 16 10 0,000 0,05251435 0,1068947 ! arginine catabolic process GO:0006527 13 10 0,000 0,05251435 0,10680434 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05251435 0,10671413 ! proline metabolic process GO:0006560 13 10 0,000 0,05251435 0,10662408 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05251435 0,10653418 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05251435 0,10644443 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05251435 0,10635483 ! V(D)J recombination GO:0033151 28 10 0,000 0,05251435 0,10626538 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05251435 0,10617608 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05251435 0,10608693 ! B cell proliferation GO:0042100 18 10 0,000 0,05251435 0,10599793 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05251435 0,10590908 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05251435 0,10582038 ! multicellular organism growth GO:0035264 18 10 0,000 0,05251435 0,10573183 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05251435 0,10564342 ! epithelial cell development GO:0002064 20 10 0,000 0,05251435 0,10555517 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05251435 0,10546706 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05251435 0,10537909 ! macroautophagy GO:0016236 17 10 0,000 0,05251435 0,10529128 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05251435 0,10520361 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05251435 0,10511608 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05251435 0,10502871 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05251435 0,10494147 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05251435 0,10485439 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05251435 0,10476744 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05251435 0,10468064 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05251435 0,10459399 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05251435 0,10450747 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05251435 0,1044211 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05251435 0,10433488 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05251435 0,10424879 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05251435 0,10416285 ! response to dsRNA GO:0043331 20 10 0,000 0,05251435 0,10407705 ! DNA ligation GO:0006266 19 10 0,000 0,05251435 0,10399139 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05251435 0,10390587 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05251435 0,10382049 ! melanosome localization GO:0032400 16 10 0,000 0,05251435 0,10373525 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05251435 0,10365015 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05251435 0,10356519 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05251435 0,10348037 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05251435 0,10339569 ! mRNA cleavage GO:0006379 17 10 0,000 0,05251435 0,10331115 ! protein sumoylation GO:0016925 15 10 0,000 0,05251435 0,10322674 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05251435 0,10314248 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05251435 0,10305835 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05251435 0,10297436 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05251435 0,1028905 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05251435 0,10280678 ! salivary gland development GO:0007431 27 10 0,000 0,05251435 0,1027232 ! prophase GO:0051324 15 10 0,000 0,05251435 0,10263975 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05251435 0,10255644 ! apical protein localization GO:0045176 15 10 0,000 0,05251435 0,10247326 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05251435 0,10239022 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05251435 0,10230732 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05251435 0,10222454 ! midbrain development GO:0030901 13 10 0,000 0,05251435 0,1021419 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05251435 0,1020594 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05251435 0,10197703 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05251435 0,10189479 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05251435 0,10181268 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05251435 0,1017307 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05251435 0,10164886 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05251435 0,10156715 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05251435 0,10148557 ! oocyte development GO:0048599 17 10 0,000 0,05251435 0,10140412 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05251435 0,1013228 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05251435 0,10124161 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05251435 0,10116056 ! activation of innate immune response GO:0002218 12 10 0,000 0,05251435 0,10107963 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05251435 0,10099883 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05251435 0,10091816 ! response to nicotine GO:0035094 20 10 0,000 0,05251435 0,10083762 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05251435 0,1007572 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05251435 0,10067692 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05251435 0,10059676 ! localization within membrane GO:0051668 20 10 0,000 0,05251435 0,10051673 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,05336686 0,10206731 ! respiratory tube development GO:0030323 150 70 1,000 0,05474752 0,10462472 ! amine catabolic process GO:0009310 117 71 1,000 0,05614072 0,10720204 ! carbohydrate transport GO:0008643 110 72 1,000 0,0575463 0,10979889 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,0575463 0,10971189 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,0575463 0,10962502 ! respiratory system development GO:0060541 153 72 1,000 0,0575463 0,10953829 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05761259 0,10957778 ! respiratory burst GO:0045730 17 11 0,000 0,05761259 0,10949123 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05761259 0,10940481 ! neuron fate specification GO:0048665 17 11 0,000 0,05761259 0,10931853 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05761259 0,10923239 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05761259 0,10914638 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05761259 0,1090605 ! thyroid gland development GO:0030878 26 11 0,000 0,05761259 0,10897476 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05761259 0,10888916 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05761259 0,10880369 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05761259 0,10871835 ! response to pain GO:0048265 24 11 0,000 0,05761259 0,10863315 ! T cell proliferation GO:0042098 26 11 0,000 0,05761259 0,10854808 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05761259 0,10846314 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05761259 0,10837834 ! bone resorption GO:0045453 16 11 0,000 0,05761259 0,10829367 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,05761259 0,10820913 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05761259 0,10812472 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05761259 0,10804045 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05761259 0,10795631 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05761259 0,10787229 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05761259 0,10778841 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05761259 0,10770466 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05761259 0,10762104 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05761259 0,10753755 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05761259 0,10745418 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05761259 0,10737095 ! lipid digestion GO:0044241 18 11 0,000 0,05761259 0,10728785 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05761259 0,10720487 ! UV protection GO:0009650 19 11 0,000 0,05761259 0,10712202 ! adult heart development GO:0007512 14 11 0,000 0,05761259 0,1070393 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05761259 0,10695671 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05761259 0,10687425 ! temperature homeostasis GO:0001659 17 11 0,000 0,05761259 0,10679191 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05761259 0,1067097 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05761259 0,10662761 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05761259 0,10654565 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05761259 0,10646382 ! regulation of organ growth GO:0046620 13 11 0,000 0,05761259 0,10638212 ! pigment granule localization GO:0051875 20 11 0,000 0,05761259 0,10630053 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05761259 0,10621908 ! vasoconstriction GO:0042310 18 11 0,000 0,05761259 0,10613775 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05761259 0,10605654 ! embryonic axis specification GO:0000578 18 11 0,000 0,05761259 0,10597546 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05761259 0,1058945 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05761259 0,10581366 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05761259 0,10573295 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05761259 0,10565236 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05761259 0,10557189 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05761259 0,10549155 ! zymogen activation GO:0031638 15 11 0,000 0,05761259 0,10541133 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05761259 0,10533123 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05761259 0,10525125 ! nucleosome positioning GO:0016584 15 11 0,000 0,05761259 0,10517139 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05761259 0,10509166 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05761259 0,10501204 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05761259 0,10493255 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05761259 0,10485317 ! acid secretion GO:0046717 18 11 0,000 0,05761259 0,10477392 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05761259 0,10469479 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05761259 0,10461577 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05761259 0,10453688 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05761259 0,1044581 ! oocyte differentiation GO:0009994 18 11 0,000 0,05761259 0,10437944 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05761259 0,1043009 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05761259 0,10422248 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05761259 0,10414417 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05761259 0,10406599 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,05761259 0,10398792 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05761259 0,10390997 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05761259 0,10383213 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05761259 0,10375441 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05761259 0,10367681 ! defense response to fungus GO:0050832 13 11 0,000 0,05761259 0,10359932 ! developmental induction GO:0031128 19 11 0,000 0,05761259 0,10352195 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05761259 0,1034447 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05761259 0,10336756 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05761259 0,10329053 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05761259 0,10321362 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05761259 0,10313683 ! nucleus localization GO:0051647 19 11 0,000 0,05761259 0,10306015 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05761259 0,10298358 ! learning or memory GO:0007611 147 73 1,000 0,05896409 0,10532115 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,05896409 0,10524302 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,06039391 0,10771516 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 0,06039391 0,10763537 ! meiosis GO:0007126 121 74 1,000 0,06039391 0,1075557 GO:0051327|M phase of meiotic cell cycle, ! eye development GO:0001654 143 74 1,000 0,06039391 0,10747615 ! organelle localization GO:0051640 136 74 1,000 0,06039391 0,10739671 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0618356 0,10987922 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0618356 0,10979812 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06268357 0,11122173 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06268357 0,11113977 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06268357 0,11105792 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06268357 0,1109762 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06268357 0,1108946 ! virus-host interaction GO:0019048 29 12 0,000 0,06268357 0,11081312 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06268357 0,11073176 ! cartilage condensation GO:0001502 20 12 0,000 0,06268357 0,11065052 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06268357 0,1105694 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06268357 0,1104884 ! protein complex disassembly GO:0043241 27 12 0,000 0,06268357 0,11040751 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06268357 0,11032675 ! hippocampus development GO:0021766 26 12 0,000 0,06268357 0,1102461 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06268357 0,11016557 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06268357 0,11008515 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06268357 0,11000486 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06268357 0,10992468 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06268357 0,10984462 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06268357 0,10976467 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06268357 0,10968484 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06268357 0,10960513 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06268357 0,10952553 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06268357 0,10944605 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06268357 0,10936669 ! forebrain cell migration GO:0021885 21 12 0,000 0,06268357 0,10928744 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06268357 0,1092083 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06268357 0,10912928 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06268357 0,10905037 ! entry into host cell GO:0030260 32 12 0,000 0,06268357 0,10897158 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06268357 0,1088929 ! monoamine transport GO:0015844 18 12 0,000 0,06268357 0,10881433 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06268357 0,10873588 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06268357 0,10865754 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06268357 0,10857931 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06268357 0,1085012 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06268357 0,10842319 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06268357 0,1083453 ! protein homotetramerization GO:0051289 21 12 0,000 0,06268357 0,10826752 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06268357 0,10818986 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06268357 0,1081123 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06268357 0,10803486 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06268357 0,10795752 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06268357 0,1078803 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06268357 0,10780319 ! cranial nerve development GO:0021545 20 12 0,000 0,06268357 0,10772619 ! fucose catabolic process GO:0019317 22 12 0,000 0,06268357 0,10764929 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06268357 0,10757251 ! histone acetylation GO:0016573 26 12 0,000 0,06268357 0,10749584 ! histone methylation GO:0016571 26 12 0,000 0,06268357 0,10741927 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06268357 0,10734282 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06268357 0,10726647 ! gland morphogenesis GO:0022612 29 12 0,000 0,06268357 0,10719024 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06268357 0,10711411 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06268357 0,10703808 ! T cell homeostasis GO:0043029 25 12 0,000 0,06268357 0,10696217 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06268357 0,10688637 ! spleen development GO:0048536 22 12 0,000 0,06268357 0,10681067 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06268357 0,10673508 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06268357 0,10665959 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06268357 0,10658421 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06268357 0,10650894 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06268357 0,10643378 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06268357 0,10635872 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06268357 0,10628376 ! response to cold GO:0009409 17 12 0,000 0,06268357 0,10620892 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06268357 0,10613417 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06268357 0,10605954 ! regulation of catabolic process GO:0009894 161 76 1,000 0,06328899 0,10700866 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,06475392 0,10940866 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,06623022 0,11182449 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,06771772 0,11425584 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06772742 0,11419214 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06772742 0,11411217 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06772742 0,11403231 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06772742 0,11395257 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06772742 0,11387294 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06772742 0,11379342 ! lipid localization GO:0010876 28 13 0,000 0,06772742 0,11371401 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06772742 0,11363471 ! organelle fusion GO:0048284 32 13 0,000 0,06772742 0,11355552 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06772742 0,11347645 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06772742 0,11339748 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06772742 0,11331862 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06772742 0,11323987 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06772742 0,11316123 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06772742 0,1130827 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06772742 0,11300428 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06772742 0,11292597 ! methionine metabolic process GO:0006555 27 13 0,000 0,06772742 0,11284777 ! plasma membrane organization GO:0007009 24 13 0,000 0,06772742 0,11276967 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06772742 0,11269169 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06772742 0,11261381 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06772742 0,11253603 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06772742 0,11245837 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06772742 0,11238081 ! response to X-ray GO:0010165 25 13 0,000 0,06772742 0,11230336 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06772742 0,11222602 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06772742 0,11214878 ! exocrine system development GO:0035272 32 13 0,000 0,06772742 0,11207165 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06772742 0,11199462 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06772742 0,1119177 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06772742 0,11184089 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06772742 0,11176418 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06772742 0,11168758 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06772742 0,11161108 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06772742 0,11153469 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06772742 0,1114584 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06772742 0,11138221 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06772742 0,11130613 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06772742 0,11123016 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06772742 0,11115428 ! ribosome assembly GO:0042255 17 13 0,000 0,06772742 0,11107851 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,06772742 0,11100285 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06772742 0,11092728 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06772742 0,11085182 ! chromatin silencing GO:0006342 26 13 0,000 0,06772742 0,11077646 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06772742 0,11070121 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06772742 0,11062605 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06772742 0,110551 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06772742 0,11047605 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06772742 0,1104012 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06772742 0,11032646 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06772742 0,11025181 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06772742 0,11017727 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06772742 0,11010282 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06772742 0,11002848 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06772742 0,10995424 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06772742 0,10988009 ! insulin secretion GO:0030073 23 13 0,000 0,06772742 0,10980605 ! actin filament polymerization GO:0030041 24 13 0,000 0,06772742 0,10973211 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06772742 0,10965826 ! acrosome reaction GO:0007340 18 13 0,000 0,06772742 0,10958452 ! response to metal ion GO:0010038 140 80 1,000 0,06921627 0,11191824 ! muscle cell differentiation GO:0042692 159 80 1,000 0,06921627 0,11184307 ! protein import into nucleus GO:0006606 158 80 1,000 0,06921627 0,11176801 ! response to hypoxia GO:0001666 171 81 1,000 0,0707257 0,1141288 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0707257 0,1140523 ! nuclear import GO:0051170 161 81 1,000 0,0707257 0,11397591 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0707257 0,11389962 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07224586 0,11626993 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,07224586 0,11619221 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,07224586 0,11611459 ! rRNA transcription GO:0009303 25 14 0,000 0,0727443 0,11683764 ! lactation GO:0007595 26 14 0,000 0,0727443 0,1167597 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0727443 0,11668186 ! reproductive cellular process GO:0048610 20 14 0,000 0,0727443 0,11660412 ! tRNA modification GO:0006400 20 14 0,000 0,0727443 0,11652649 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0727443 0,11644896 ! regulation of S phase GO:0033261 23 14 0,000 0,0727443 0,11637154 ! water transport GO:0006833 21 14 0,000 0,0727443 0,11629421 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0727443 0,11621699 ! non-recombinational repair GO:0000726 25 14 0,000 0,0727443 0,11613987 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0727443 0,11606286 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0727443 0,11598594 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0727443 0,11590913 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0727443 0,11583242 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0727443 0,11575581 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0727443 0,11567931 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0727443 0,1156029 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0727443 0,11552659 ! arginine metabolic process GO:0006525 17 14 0,000 0,0727443 0,11545039 ! regulation of heart rate GO:0002027 24 14 0,000 0,0727443 0,11537429 ! organic alcohol transport GO:0015850 29 14 0,000 0,0727443 0,11529828 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0727443 0,11522238 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0727443 0,11514657 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0727443 0,11507087 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0727443 0,11499526 ! L-amino acid transport GO:0015807 30 14 0,000 0,0727443 0,11491976 ! stem cell development GO:0048864 43 14 0,000 0,0727443 0,11484435 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0727443 0,11476904 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0727443 0,11469383 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0727443 0,11461872 ! cerebellum development GO:0021549 21 14 0,000 0,0727443 0,11454371 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0727443 0,1144688 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0727443 0,11439398 ! response to gamma radiation GO:0010332 28 14 0,000 0,0727443 0,11431926 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0727443 0,11424464 ! NADP metabolic process GO:0006739 24 14 0,000 0,0727443 0,11417012 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0727443 0,11409569 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0727443 0,11402136 ! intestinal absorption GO:0050892 25 14 0,000 0,0727443 0,11394713 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0727443 0,11387299 ! oxygen transport GO:0015671 21 14 0,000 0,0727443 0,11379895 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0727443 0,11372501 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0727443 0,11365116 ! regulation of axon extension GO:0030516 37 14 0,000 0,0727443 0,11357741 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0727443 0,11350376 ! response to oxygen levels GO:0070482 176 83 1,000 0,07377659 0,11503985 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,07531774 0,11736689 ! negative regulation of transport GO:0051051 153 84 1,000 0,07531774 0,11729092 ! response to unfolded protein GO:0006986 131 85 1,000 0,07686914 0,11962946 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07773435 0,12089777 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07773435 0,12081967 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07773435 0,12074167 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07773435 0,12066377 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07773435 0,12058597 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07773435 0,12050828 ! copper ion transport GO:0006825 20 15 0,000 0,07773435 0,12043068 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07773435 0,12035318 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07773435 0,12027579 ! sulfate transport GO:0008272 23 15 0,000 0,07773435 0,12019849 ! response to cAMP GO:0051591 22 15 0,000 0,07773435 0,12012129 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07773435 0,12004419 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07773435 0,11996719 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07773435 0,11989029 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07773435 0,11981348 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07773435 0,11973678 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07773435 0,11966017 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07773435 0,11958366 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07773435 0,11950725 ! pituitary gland development GO:0021983 29 15 0,000 0,07773435 0,11943094 ! vesicle coating GO:0006901 33 15 0,000 0,07773435 0,11935472 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07773435 0,1192786 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07773435 0,11920258 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07773435 0,11912665 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07773435 0,11905083 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07773435 0,11897509 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07773435 0,11889946 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07773435 0,11882392 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07773435 0,11874847 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07773435 0,11867313 ! histone deacetylation GO:0016575 20 15 0,000 0,07773435 0,11859787 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07773435 0,11852272 ! tissue regeneration GO:0042246 26 15 0,000 0,07773435 0,11844765 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07773435 0,11837269 ! water homeostasis GO:0030104 27 15 0,000 0,07773435 0,11829782 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07773435 0,11822304 ! muscle maintenance GO:0046716 26 15 0,000 0,07773435 0,11814836 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07773435 0,11807377 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07773435 0,11799927 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07773435 0,11792487 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07773435 0,11785057 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07773435 0,11777635 ! cell killing GO:0001906 29 15 0,000 0,07773435 0,11770223 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07773435 0,11762821 ! detection of bacterium GO:0016045 18 15 0,000 0,07773435 0,11755427 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07773435 0,11748043 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07773435 0,11740668 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07773435 0,11733303 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07773435 0,11725947 ! peptide hormone processing GO:0016486 23 15 0,000 0,07773435 0,11718599 ! response to inorganic substance GO:0010035 153 86 1,000 0,07843065 0,11816164 ! oxidative phosphorylation GO:0006119 133 86 1,000 0,07843065 0,11808769 ! amine transport GO:0015837 155 86 1,000 0,07843065 0,11801384 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08000211 0,12030317 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,08000211 0,12022803 ! regulation of protein transport GO:0051223 154 87 1,000 0,08000211 0,12015298 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,08158337 0,1224514 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,08158337 0,12237506 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08269771 0,12396928 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08269771 0,12389209 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08269771 0,12381499 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08269771 0,12373799 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08269771 0,12366109 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08269771 0,12358428 ! bone remodeling GO:0046849 27 16 0,000 0,08269771 0,12350757 ! filopodium assembly GO:0046847 32 16 0,000 0,08269771 0,12343095 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08269771 0,12335443 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08269771 0,123278 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08269771 0,12320166 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08269771 0,12312543 ! startle response GO:0001964 28 16 0,000 0,08269771 0,12304928 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08269771 0,12297323 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08269771 0,12289728 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08269771 0,12282141 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08269771 0,12274564 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08269771 0,12266997 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08269771 0,12259439 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08269771 0,1225189 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08269771 0,1224435 ! response to osmotic stress GO:0006970 25 16 0,000 0,08269771 0,1223682 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08269771 0,12229299 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08269771 0,12221787 ! fructose metabolic process GO:0006000 25 16 0,000 0,08269771 0,12214284 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08269771 0,12206791 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08269771 0,12199306 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08269771 0,12191831 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08269771 0,12184366 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08269771 0,12176909 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08269771 0,12169461 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08269771 0,12162023 ! DNA replication initiation GO:0006270 27 16 0,000 0,08269771 0,12154593 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08269771 0,12147173 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08269771 0,12139761 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08269771 0,12132359 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08269771 0,12124966 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08269771 0,12117582 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08269771 0,12110206 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08269771 0,1210284 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08269771 0,12095483 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08269771 0,12088134 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08269771 0,12080795 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08269771 0,12073464 ! defense response to virus GO:0051607 37 16 0,000 0,08269771 0,12066142 ! ossification GO:0001503 188 90 1,000 0,08477471 0,12361694 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,08477471 0,12354207 ! bone development GO:0060348 189 91 1,000 0,08638449 0,1258118 ! sterol metabolic process GO:0016125 152 91 1,000 0,08638449 0,12573568 ! response to protein stimulus GO:0051789 149 91 1,000 0,08638449 0,12565967 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08763452 0,127401 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08763452 0,12732407 ! metencephalon development GO:0022037 30 17 0,000 0,08763452 0,12724723 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08763452 0,12717048 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08763452 0,12709383 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08763452 0,12701726 ! signal complex assembly GO:0007172 41 17 0,000 0,08763452 0,12694079 ! endothelial cell migration GO:0043542 28 17 0,000 0,08763452 0,12686442 ! inositol metabolic process GO:0006020 28 17 0,000 0,08763452 0,12678813 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08763452 0,12671193 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08763452 0,12663583 ! glial cell development GO:0021782 27 17 0,000 0,08763452 0,12655982 ! limbic system development GO:0021761 36 17 0,000 0,08763452 0,1264839 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08763452 0,12640807 ! adult walking behavior GO:0007628 33 17 0,000 0,08763452 0,12633233 ! heart looping GO:0001947 30 17 0,000 0,08763452 0,12625668 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08763452 0,12618112 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08763452 0,12610566 ! myoblast differentiation GO:0045445 45 17 0,000 0,08763452 0,12603028 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08763452 0,12595499 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08763452 0,1258798 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08763452 0,12580469 ! glycine metabolic process GO:0006544 28 17 0,000 0,08763452 0,12572967 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,08763452 0,12565474 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08763452 0,1255799 ! NAD metabolic process GO:0019674 29 17 0,000 0,08763452 0,12550515 ! membrane budding GO:0006900 37 17 0,000 0,08763452 0,12543049 ! DNA integration GO:0015074 29 17 0,000 0,08763452 0,12535592 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,08763452 0,12528144 ! regulation of protein binding GO:0043393 33 17 0,000 0,08763452 0,12520704 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08763452 0,12513273 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08763452 0,12505852 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08763452 0,12498439 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08763452 0,12491034 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08763452 0,12483639 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08763452 0,12476252 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08763452 0,12468874 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08763452 0,12461505 ! steroid catabolic process GO:0006706 31 17 0,000 0,08763452 0,12454144 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08763452 0,12446792 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08763452 0,12439449 ! gas transport GO:0015669 25 17 0,000 0,08763452 0,12432114 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08763452 0,12424788 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08763452 0,12417471 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08763452 0,12410162 ! microspike assembly GO:0030035 36 17 0,000 0,08763452 0,12402862 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08763452 0,12395571 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08763452 0,12388288 ! vitamin metabolic process GO:0006766 139 92 1,000 0,08800349 0,12433141 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,08963155 0,12655722 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,08963155 0,12648299 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,08963155 0,12640885 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08963155 0,1263348 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,09126854 0,1285668 ! female pregnancy GO:0007565 164 94 1,000 0,09126854 0,12849157 ! transcription initiation GO:0006352 153 94 1,000 0,09126854 0,12841643 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09254493 0,13013623 ! neuron maturation GO:0042551 42 18 0,000 0,09254493 0,13006022 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09254493 0,12998429 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09254493 0,12990846 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,09254493 0,12983271 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09254493 0,12975705 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09254493 0,12968148 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09254493 0,12960599 ! memory GO:0007613 31 18 0,000 0,09254493 0,1295306 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09254493 0,12945529 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09254493 0,12938007 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09254493 0,12930493 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09254493 0,12922989 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09254493 0,12915493 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09254493 0,12908005 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09254493 0,12900527 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09254493 0,12893057 ! response to retinoic acid GO:0032526 26 18 0,000 0,09254493 0,12885596 ! response to fungus GO:0009620 21 18 0,000 0,09254493 0,12878143 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09254493 0,12870699 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09254493 0,12863264 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09254493 0,12855837 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09254493 0,12848419 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09254493 0,12841009 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09254493 0,12833608 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09254493 0,12826215 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09254493 0,12818831 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09254493 0,12811455 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09254493 0,12804088 ! nerve development GO:0021675 28 18 0,000 0,09254493 0,1279673 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09254493 0,12789379 ! forebrain development GO:0030900 188 95 1,000 0,09291431 0,12833056 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,09291431 0,12825693 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,09456873 0,1304658 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! detection of stimulus GO:0051606 151 96 1,000 0,09456873 0,13039104 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,09623165 0,13260787 ! protein ubiquitination GO:0016567 217 97 1,000 0,09623165 0,13253197 ! regulation of protein localization GO:0032880 176 97 1,000 0,09623165 0,13245615 ! positive regulation of translation GO:0045727 30 19 0,000 0,09742907 0,13402764 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09742907 0,13395105 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09742907 0,13387455 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09742907 0,13379814 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09742907 0,13372181 ! lipid phosphorylation GO:0046834 35 19 0,000 0,09742907 0,13364557 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09742907 0,13356942 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09742907 0,13349336 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09742907 0,13341738 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09742907 0,13334149 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09742907 0,13326568 ! cerebral cortex development GO:0021987 36 19 0,000 0,09742907 0,13318996 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09742907 0,13311433 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09742907 0,13303878 ! heme metabolic process GO:0042168 36 19 0,000 0,09742907 0,13296332 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09742907 0,13288794 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09742907 0,13281265 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,09742907 0,13273745 ! peptide cross-linking GO:0018149 37 19 0,000 0,09742907 0,13266233 ! protein export from nucleus GO:0006611 36 19 0,000 0,09742907 0,13258729 ! heart process GO:0003015 30 19 0,000 0,09742907 0,13251234 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09742907 0,13243748 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09742907 0,1323627 ! visual learning GO:0008542 36 19 0,000 0,09742907 0,132288 ! cellular pigmentation GO:0033059 36 19 0,000 0,09742907 0,13221339 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09742907 0,13213886 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09742907 0,13206441 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09742907 0,13199005 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09742907 0,13191578 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09742907 0,13184158 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09742907 0,13176747 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09742907 0,13169345 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09742907 0,1316195 ! cilium assembly GO:0042384 37 19 0,000 0,09742907 0,13154564 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09742907 0,13147186 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,09790294 0,13203726 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,09958246 0,13422711 GO:0060538|skeletal muscle organ development, ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10228708 0,13779547 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10228708 0,13771836 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10228708 0,13764134 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10228708 0,1375644 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10228708 0,13748755 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,10228708 0,13741078 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,10228708 0,1373341 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10228708 0,13725751 ! response to vitamin GO:0033273 31 20 0,000 0,10228708 0,137181 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10228708 0,13710458 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10228708 0,13702824 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10228708 0,13695198 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10228708 0,13687581 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10228708 0,13679973 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10228708 0,13672373 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10228708 0,13664781 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10228708 0,13657198 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10228708 0,13649624 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,10228708 0,13642057 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,10228708 0,13634499 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10228708 0,1362695 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10228708 0,13619409 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10228708 0,13611876 ! stem cell differentiation GO:0048863 53 20 0,000 0,10228708 0,13604351 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10228708 0,13596835 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10228708 0,13589327 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10228708 0,13581828 ! sensory perception of pain GO:0019233 30 20 0,000 0,10228708 0,13574336 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10228708 0,13566853 ! diencephalon development GO:0021536 34 20 0,000 0,10228708 0,13559378 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10228708 0,13551912 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10228708 0,13544453 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10228708 0,13537003 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10228708 0,13529561 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10228708 0,13522127 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10228708 0,13514702 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10228708 0,13507284 ! regulation of glucose import GO:0046324 29 20 0,000 0,10228708 0,13499875 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10228708 0,13492473 ! actin filament-based movement GO:0030048 43 20 0,000 0,10228708 0,1348508 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10228708 0,13477695 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10228708 0,13470318 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10228708 0,13462949 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10228708 0,13455589 ! regulation of cell killing GO:0031341 42 21 0,000 0,10711911 0,14083528 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10711911 0,14075837 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10711911 0,14068153 ! hormone secretion GO:0046879 38 21 0,000 0,10711911 0,14060478 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10711911 0,14052812 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10711911 0,14045154 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10711911 0,14037504 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10711911 0,14029862 ! axis specification GO:0009798 38 21 0,000 0,10711911 0,14022229 ! ovarian follicle development GO:0001541 35 21 0,000 0,10711911 0,14014604 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,10711911 0,14006987 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10711911 0,13999379 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10711911 0,13991779 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10711911 0,13984187 ! cell aging GO:0007569 44 21 0,000 0,10711911 0,13976604 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10711911 0,13969028 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10711911 0,13961461 ! cytolysis GO:0019835 24 21 0,000 0,10711911 0,13953902 ! vasodilation GO:0042311 39 21 0,000 0,10711911 0,13946351 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10711911 0,13938809 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10711911 0,13931274 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10711911 0,13923748 ! oogenesis GO:0048477 36 21 0,000 0,10711911 0,13916229 ! DNA modification GO:0006304 34 21 0,000 0,10711911 0,13908719 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,10711911 0,13901217 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10711911 0,13893723 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10711911 0,13886238 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10711911 0,1387876 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10711911 0,1387129 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10711911 0,13863828 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10711911 0,13856375 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10711911 0,13848929 ! collagen catabolic process GO:0030574 28 21 0,000 0,10711911 0,13841491 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10711911 0,13834062 ! gut development GO:0048565 39 21 0,000 0,10711911 0,1382664 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11192528 0,14439262 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11192528 0,14431524 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11192528 0,14423794 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11192528 0,14416072 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,11192528 0,14408359 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11192528 0,14400654 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11192528 0,14392957 ! regeneration GO:0031099 41 22 0,000 0,11192528 0,14385269 ! keratinization GO:0031424 28 22 0,000 0,11192528 0,14377588 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11192528 0,14369916 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11192528 0,14362252 ! sensory perception of taste GO:0050909 28 22 0,000 0,11192528 0,14354597 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11192528 0,14346949 ! vacuolar transport GO:0007034 36 22 0,000 0,11192528 0,14339309 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11192528 0,14331678 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11192528 0,14324055 ! fucose metabolic process GO:0006004 39 22 0,000 0,11192528 0,1431644 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11192528 0,14308833 ! ureteric bud development GO:0001657 43 22 0,000 0,11192528 0,14301234 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11192528 0,14293643 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11192528 0,1428606 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11192528 0,14278485 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,11192528 0,14270918 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11192528 0,1426336 ! sarcomere organization GO:0045214 30 22 0,000 0,11192528 0,14255809 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,11192528 0,14248266 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11192528 0,14240731 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11192528 0,14233205 ! protein stabilization GO:0050821 39 22 0,000 0,11192528 0,14225686 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11670575 0,1482545 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11670575 0,14817627 ! viral genome replication GO:0019079 41 23 0,000 0,11670575 0,14809812 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11670575 0,14802005 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11670575 0,14794206 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11670575 0,14786416 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11670575 0,14778633 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11670575 0,14770859 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11670575 0,14763093 ! visual behavior GO:0007632 42 23 0,000 0,11670575 0,14755335 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11670575 0,14747586 ! response to ethanol GO:0045471 46 23 0,000 0,11670575 0,14739844 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11670575 0,14732111 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11670575 0,14724385 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11670575 0,14716668 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11670575 0,14708959 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11670575 0,14701258 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11670575 0,14693565 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,11670575 0,1468588 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11670575 0,14678203 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11670575 0,14670535 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11670575 0,14662874 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11670575 0,14655221 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11670575 0,14647576 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11670575 0,14639939 ! fatty acid transport GO:0015908 44 23 0,000 0,11670575 0,1463231 ! platelet activation GO:0030168 37 23 0,000 0,11670575 0,14624689 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11670575 0,14617076 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11670575 0,14609471 ! hormone transport GO:0009914 40 23 0,000 0,11670575 0,14601874 ! cell-cell recognition GO:0009988 25 23 0,000 0,11670575 0,14594284 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11670575 0,14586703 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11670575 0,14579129 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11670575 0,14571564 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11670575 0,14564006 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11670575 0,14556456 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,12146064 0,15141673 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12146064 0,15133832 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,12146064 0,15125999 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12146064 0,15118174 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12146064 0,15110357 ! vesicle docking GO:0048278 47 24 0,000 0,12146064 0,15102548 ! spinal cord development GO:0021510 47 24 0,000 0,12146064 0,15094747 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12146064 0,15086954 ! digestive system process GO:0022600 39 24 0,000 0,12146064 0,15079169 ! regulation of behavior GO:0050795 43 24 0,000 0,12146064 0,15071392 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12146064 0,15063624 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12146064 0,15055863 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12146064 0,1504811 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12146064 0,15040365 ! membrane depolarization GO:0051899 39 24 0,000 0,12146064 0,15032628 ! pallium development GO:0021543 49 24 0,000 0,12146064 0,150249 ! pentose metabolic process GO:0019321 35 24 0,000 0,12146064 0,15017179 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,12146064 0,15009466 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,12146064 0,15001761 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12146064 0,14994063 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12146064 0,14986374 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12146064 0,14978693 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12146064 0,14971019 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12146064 0,14963354 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12146064 0,14955696 ! regulation of amine transport GO:0051952 40 24 0,000 0,12146064 0,14948046 ! protein tetramerization GO:0051262 52 24 0,000 0,12146064 0,14940404 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12619009 0,15514224 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,12619009 0,155063 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12619009 0,15498385 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12619009 0,15490477 ! phototransduction GO:0007602 33 25 0,000 0,12619009 0,15482578 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12619009 0,15474687 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,12619009 0,15466804 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12619009 0,15458929 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,12619009 0,15451061 ! receptor metabolic process GO:0043112 46 25 0,000 0,12619009 0,15443202 ! chromosome condensation GO:0030261 45 25 0,000 0,12619009 0,15435351 ! response to starvation GO:0042594 42 25 0,000 0,12619009 0,15427508 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12619009 0,15419673 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,12619009 0,15411846 ! neural crest cell development GO:0014032 54 25 0,000 0,12619009 0,15404026 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12619009 0,15396215 ! negative regulation of cell development GO:0010721 73 25 0,000 0,12619009 0,15388411 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12619009 0,15380616 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12619009 0,15372828 ! interaction with host GO:0051701 62 25 0,000 0,12619009 0,15365048 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12619009 0,15357277 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12619009 0,15349512 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12619009 0,15341756 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,12619009 0,15334008 ! immunoglobulin production GO:0002377 55 25 0,000 0,12619009 0,15326267 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12619009 0,15318535 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12619009 0,1531081 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12619009 0,15303093 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12619009 0,15295383 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12619009 0,15287682 ! neural tube closure GO:0001843 49 25 0,000 0,12619009 0,15279988 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12619009 0,15272302 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13089424 0,15833662 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13089424 0,15825705 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13089424 0,15817757 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13089424 0,15809816 ! initiation of viral infection GO:0019059 57 26 0,000 0,13089424 0,15801883 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13089424 0,15793959 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13089424 0,15786042 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13089424 0,15778133 ! molting cycle process GO:0022404 50 26 0,000 0,13089424 0,15770232 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,13089424 0,15762339 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13089424 0,15754454 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13089424 0,15746577 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13089424 0,15738707 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13089424 0,15730846 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13089424 0,15722992 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13089424 0,15715146 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13089424 0,15707309 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13089424 0,15699478 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13089424 0,15691656 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13089424 0,15683841 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13089424 0,15676035 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13089424 0,15668236 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13089424 0,15660444 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13089424 0,15652661 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,13557322 0,16204131 ! iron ion transport GO:0006826 59 27 0,000 0,13557322 0,16196085 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13557322 0,16188048 ! protein amino acid acylation GO:0043543 55 27 0,000 0,13557322 0,16180018 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13557322 0,16171996 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13557322 0,16163982 ! fat cell differentiation GO:0045444 50 27 0,000 0,13557322 0,16155976 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13557322 0,16147978 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,13557322 0,16139988 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13557322 0,16132006 ! autophagy GO:0006914 41 27 0,000 0,13557322 0,16124031 ! response to toxin GO:0009636 47 27 0,000 0,13557322 0,16116065 ! primary neural tube formation GO:0014020 51 27 0,000 0,13557322 0,16108107 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13557322 0,16100156 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13557322 0,16092213 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13557322 0,16084278 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13557322 0,16076351 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13557322 0,16068431 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14022716 0,16611844 ! circadian rhythm GO:0007623 50 28 0,000 0,14022716 0,16603668 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14022716 0,16595501 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14022716 0,16587342 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14022716 0,16579191 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,14022716 0,16571048 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14022716 0,16562913 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14022716 0,16554786 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14022716 0,16546667 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14022716 0,16538556 ! synaptogenesis GO:0007416 42 28 0,000 0,14022716 0,16530453 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14022716 0,16522358 ! translational initiation GO:0006413 65 29 0,000 0,1448562 0,17059423 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,1448562 0,17051077 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1448562 0,17042739 ! regulation of pH GO:0006885 43 29 0,000 0,1448562 0,17034409 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1448562 0,17026088 ! catechol metabolic process GO:0009712 54 29 0,000 0,1448562 0,17017774 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,1448562 0,17009469 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,1448562 0,17001171 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1448562 0,16992882 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1448562 0,16984601 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1448562 0,16976328 ! cell fate determination GO:0001709 60 29 0,000 0,1448562 0,16968063 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1448562 0,16959806 ! detection of light stimulus GO:0009583 38 29 0,000 0,1448562 0,16951557 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,1448562 0,16943316 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,1448562 0,16935083 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,1448562 0,16926858 ! regulation of coagulation GO:0050818 46 29 0,000 0,1448562 0,16918642 ! phenol metabolic process GO:0018958 55 30 0,000 0,14946047 0,17447933 ! zinc ion transport GO:0006829 45 30 0,000 0,14946047 0,17439471 ! membrane docking GO:0022406 61 30 0,000 0,14946047 0,17431017 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14946047 0,17422572 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14946047 0,17414135 ! acute-phase response GO:0006953 49 30 0,000 0,14946047 0,17405706 ! myofibril assembly GO:0030239 47 30 0,000 0,14946047 0,17397285 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14946047 0,17388873 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14946047 0,17380468 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,14946047 0,17372072 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14946047 0,17363684 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14946047 0,17355304 ! eye morphogenesis GO:0048592 60 30 0,000 0,14946047 0,17346932 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1540401 0,1786984 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1540401 0,17861228 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1540401 0,17852625 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1540401 0,17844029 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1540401 0,17835442 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1540401 0,17826863 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1540401 0,17818293 ! ovulation cycle process GO:0022602 49 31 0,000 0,1540401 0,1780973 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1540401 0,17801176 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1540401 0,1779263 ! mesoderm formation GO:0001707 69 31 0,000 0,1540401 0,17784092 ! natural killer cell activation GO:0030101 45 31 0,000 0,1540401 0,17775563 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1540401 0,17767042 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1540401 0,17758528 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1540401 0,17750023 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15859523 0,18266162 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15859523 0,18257422 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15859523 0,1824869 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15859523 0,18239967 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15859523 0,18231253 ! spliceosome assembly GO:0000245 67 32 0,000 0,15859523 0,18222546 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15859523 0,18213848 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15859523 0,18205158 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15859523 0,18196477 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,15859523 0,18187804 ! muscle cell development GO:0055001 49 32 0,000 0,15859523 0,18179139 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15859523 0,18170482 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15859523 0,18161833 ! ovulation cycle GO:0042698 51 32 0,000 0,15859523 0,18153193 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15859523 0,18144561 ! hindbrain development GO:0030902 61 32 0,000 0,15859523 0,18135937 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15859523 0,18127322 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15859523 0,18118714 ! gene silencing GO:0016458 65 32 0,000 0,15859523 0,18110115 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,16312598 0,18618648 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16312598 0,1860982 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16312598 0,18601 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16312598 0,18592188 ! cell fate specification GO:0001708 52 33 0,000 0,16312598 0,18583385 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,16312598 0,18574591 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16312598 0,18565804 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16312598 0,18557026 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16312598 0,18548256 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16763248 0,19051665 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16763248 0,1904267 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,16763248 0,19033683 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16763248 0,19024705 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16763248 0,19015735 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16763248 0,19006774 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16763248 0,18997821 ! spermatid development GO:0007286 63 34 0,000 0,16763248 0,18988877 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16763248 0,18979941 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16763248 0,18971013 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,16763248 0,18962094 ! regulation of muscle development GO:0048634 70 35 0,000 0,17211486 0,19459979 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17211486 0,19450839 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,17211486 0,19441707 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,17211486 0,19432584 ! female gonad development GO:0008585 58 35 0,000 0,17211486 0,19423469 ! telencephalon development GO:0021537 68 35 0,000 0,17211486 0,19414363 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,17211486 0,19405265 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17211486 0,19396176 ! neural tube formation GO:0001841 67 35 0,000 0,17211486 0,19387095 ! vesicle localization GO:0051648 64 35 0,000 0,17211486 0,19378023 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,17657325 0,19870685 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,17657325 0,19861396 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17657325 0,19852115 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17657325 0,19842842 ! regulation of proteolysis GO:0030162 72 36 0,000 0,17657325 0,19833578 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17657325 0,19824323 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17657325 0,19815077 ! aerobic respiration GO:0009060 55 36 0,000 0,17657325 0,19805839 ! embryonic organ development GO:0048568 57 36 0,000 0,17657325 0,1979661 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18100779 0,20284338 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18100779 0,20274894 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18100779 0,2026546 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18100779 0,20256034 ! organic anion transport GO:0015711 68 37 0,000 0,18100779 0,20246617 ! tissue remodeling GO:0048771 76 37 0,000 0,18100779 0,20237209 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,18100779 0,20227809 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18100779 0,20218418 ! glycogen metabolic process GO:0005977 61 37 0,000 0,18100779 0,20209036 ! pigment metabolic process GO:0042440 80 37 0,000 0,18100779 0,20199663 ! spermatid differentiation GO:0048515 66 37 0,000 0,18100779 0,20190298 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18541858 0,20672711 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18541858 0,20663136 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18541858 0,2065357 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18541858 0,20644012 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,18541858 0,20634464 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,18541858 0,20624924 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18541858 0,20615393 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18541858 0,20605871 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18541858 0,20596358 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,18541858 0,20586853 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18541858 0,20577357 ! glucan metabolic process GO:0044042 62 38 0,000 0,18541858 0,2056787 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,18980577 0,21044824 ! segmentation GO:0035282 67 39 0,000 0,18980577 0,2103513 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18980577 0,21025446 ! RNA modification GO:0009451 57 39 0,000 0,18980577 0,2101577 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18980577 0,21006103 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,19416947 0,21479161 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,19416947 0,2146929 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19416947 0,21459428 ! feeding behavior GO:0007631 59 40 0,000 0,19416947 0,21449575 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,19416947 0,21439731 ! mesenchymal cell development GO:0014031 87 40 0,000 0,19416947 0,21429897 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19416947 0,21420071 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19850982 0,21888846 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19850982 0,21878819 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,19850982 0,21868801 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19850982 0,21858793 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19850982 0,21848793 ! T cell differentiation GO:0030217 81 41 0,000 0,19850982 0,21838803 ! female gamete generation GO:0007292 61 41 0,000 0,19850982 0,21828822 ! polyol metabolic process GO:0019751 66 41 0,000 0,19850982 0,2181885 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,20282693 0,22283177 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,20282693 0,22273007 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,20282693 0,22262846 ! regulation of tube size GO:0035150 71 42 0,000 0,20282693 0,22252694 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,20282693 0,22242552 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,20282693 0,22232418 ! neuron migration GO:0001764 79 42 0,000 0,20282693 0,22222294 ! regulation of protein secretion GO:0050708 71 42 0,000 0,20282693 0,2221218 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20712093 0,22672109 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20712093 0,22661798 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,20712093 0,22651498 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,20712093 0,22641206 ! neural tube development GO:0021915 77 43 0,000 0,20712093 0,22630924 ! striated muscle contraction GO:0006941 77 43 0,000 0,20712093 0,22620651 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20712093 0,22610388 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21139194 0,23066168 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21139194 0,23055712 ! double-strand break repair GO:0006302 81 44 0,000 0,21139194 0,23045265 ! biopolymer methylation GO:0043414 84 44 0,000 0,21139194 0,23034828 ! B cell differentiation GO:0030183 107 44 0,000 0,21139194 0,230244 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,21139194 0,23013982 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,21139194 0,23003573 ! developmental growth GO:0048589 82 44 0,000 0,21139194 0,22993174 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,21564008 0,23444647 ! glycolysis GO:0006096 65 45 0,000 0,21564008 0,23434058 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,21564008 0,23423478 ! leukocyte migration GO:0050900 68 45 0,000 0,21564008 0,23412908 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,21564008 0,23402347 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,21564008 0,23391796 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,21564008 0,23381255 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,21564008 0,23370723 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,21564008 0,233602 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,21564008 0,23349687 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21986549 0,23796508 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,21986549 0,23785808 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,21986549 0,23775117 ! positive regulation of defense response GO:0031349 76 47 0,000 0,22406827 0,24218699 ! response to calcium ion GO:0051592 81 47 0,000 0,22406827 0,24207824 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,22406827 0,24196959 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,22406827 0,24186104 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22406827 0,24175258 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,22406827 0,24164422 ! methylation GO:0032259 90 47 0,000 0,22406827 0,24153595 ! protein homooligomerization GO:0051260 76 47 0,000 0,22406827 0,24142779 ! mitochondrial transport GO:0006839 82 48 0,000 0,22824854 0,24582184 ! Notch signaling pathway GO:0007219 96 48 0,000 0,22824854 0,24571186 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,22824854 0,24560197 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,22824854 0,24549218 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,22824854 0,24538248 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,22824854 0,24527289 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,23240644 0,24962942 ! regulation of ion transport GO:0043269 77 49 0,000 0,23240644 0,24951802 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,23240644 0,24940673 ! peptide metabolic process GO:0006518 76 49 0,000 0,23240644 0,24929554 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,23240644 0,24918444 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23240644 0,24907345 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,23240644 0,24896255 ! neuromuscular process GO:0050905 99 50 0,000 0,23654207 0,25328003 ! regulation of ossification GO:0030278 117 50 0,000 0,23654207 0,25316736 ! histone modification GO:0016570 91 50 0,000 0,23654207 0,25305479 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,23654207 0,25294232 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,23654207 0,25282995 ! positive regulation of binding GO:0051099 78 51 0,000 0,24065556 0,25711246 ! viral infectious cycle GO:0019058 99 51 0,000 0,24065556 0,25699834 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,24065556 0,25688432 ! excretion GO:0007588 83 51 0,000 0,24065556 0,25677041 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24065556 0,25665659 ! chromatin remodeling GO:0006338 109 51 0,000 0,24065556 0,25654287 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,24065556 0,25642926 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,24065556 0,25631574 ! regulation of cell shape GO:0008360 125 51 0,000 0,24065556 0,25620233 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,24065556 0,25608902 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,24474701 0,26032773 ! membrane fusion GO:0006944 110 52 0,000 0,24474701 0,26021269 ! covalent chromatin modification GO:0016569 101 52 0,000 0,24474701 0,26009776 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,24474701 0,25998292 ! amino acid activation GO:0043038 92 52 0,000 0,24474701 0,25986819 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,24474701 0,25975356 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,24881656 0,2639562 ! RNA catabolic process GO:0006401 93 53 0,000 0,24881656 0,26383986 ! regulation of translational initiation GO:0006446 82 53 0,000 0,24881656 0,26372364 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,24881656 0,26360751 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,24881656 0,26349148 ! cell maturation GO:0048469 100 53 0,000 0,24881656 0,26337556 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,24881656 0,26325974 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,24881656 0,26314402 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,25286432 0,26730736 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25286432 0,26718997 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,25286432 0,26707267 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25286432 0,26695549 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,25286432 0,2668384 ! chloride transport GO:0006821 90 55 0,000 0,2568904 0,27096813 ! glucose catabolic process GO:0006007 82 55 0,000 0,2568904 0,27084938 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,2568904 0,27073075 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,2568904 0,27061221 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,2568904 0,27049378 ! gastrulation GO:0007369 112 55 0,000 0,2568904 0,27037546 ! heart morphogenesis GO:0003007 97 55 0,000 0,2568904 0,27025723 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,2568904 0,27013911 ! RNA elongation GO:0006354 79 55 0,000 0,2568904 0,2700211 ! nuclear export GO:0051168 97 55 0,000 0,2568904 0,26990319 ! regulation of actin filament length GO:0030832 105 56 0,000 0,26089491 0,2739909 ! sensory perception of smell GO:0007608 80 56 0,000 0,26089491 0,27387136 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,26089491 0,27375192 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,26487798 0,27781012 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,26487798 0,27768907 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,26883972 0,28171967 ! regulation of endocytosis GO:0030100 91 58 0,000 0,26883972 0,28159702 ! adult behavior GO:0030534 99 58 0,000 0,26883972 0,28147448 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,26883972 0,28135205 ! positive regulation of secretion GO:0051047 95 59 0,000 0,27278023 0,28535184 ! regulation of cellular component size GO:0032535 109 59 0,000 0,27278023 0,28522783 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,27278023 0,28510393 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,27278023 0,28498013 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,27669964 0,28894937 ! regulation of heart contraction GO:0008016 110 60 0,000 0,27669964 0,28882401 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,27669964 0,28869876 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,28059806 0,29263933 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,28059806 0,29251253 ! mesoderm development GO:0007498 119 61 0,000 0,28059806 0,29238585 ! tRNA processing GO:0008033 89 61 0,000 0,28059806 0,29225927 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,28059806 0,29213281 ! viral reproductive process GO:0022415 126 62 0,000 0,28447559 0,29604164 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,28833235 0,29992548 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,29216845 0,30378448 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29216845 0,30365326 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29216845 0,30352215 ! single fertilization GO:0007338 75 64 0,000 0,29216845 0,30339115 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,295984 0,30722067 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,295984 0,30708819 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,295984 0,30695582 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,29977911 0,31075766 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,29977911 0,31062383 ! secondary metabolic process GO:0019748 116 66 0,000 0,29977911 0,31049011 ! developmental maturation GO:0021700 116 66 0,000 0,29977911 0,31035651 ! cell projection assembly GO:0030031 120 66 0,000 0,29977911 0,31022303 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,30355388 0,31399426 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,30355388 0,31385932 ! hexose catabolic process GO:0019320 104 67 0,000 0,30355388 0,3137245 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,30355388 0,3135898 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,30355388 0,31345521 ! adaptive immune response GO:0002250 119 67 0,000 0,30355388 0,31332074 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,30355388 0,31318638 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,30730844 0,31692417 ! viral reproduction GO:0016032 134 68 0,000 0,30730844 0,31678839 ! regulation of lipase activity GO:0060191 130 68 0,000 0,30730844 0,31665272 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,30730844 0,31651716 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,31104287 0,32022642 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31104287 0,32008946 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,31104287 0,31995261 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31104287 0,31981587 ! appendage morphogenesis GO:0035107 135 70 0,000 0,3147573 0,32349682 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,31845182 0,32715417 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,31845182 0,32701454 ! B cell activation GO:0042113 160 71 0,000 0,31845182 0,32687503 ! regulation of immune effector process GO:0002697 137 71 0,000 0,31845182 0,32673564 ! acute inflammatory response GO:0002526 113 72 0,000 0,32212654 0,33036507 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,32212654 0,33022431 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,32212654 0,33008367 ! regulation of blood pressure GO:0008217 125 73 0,000 0,32578158 0,33368688 ! fertilization GO:0009566 90 73 0,000 0,32578158 0,33354488 ! transition metal ion transport GO:0000041 126 74 0,000 0,32941703 0,33712351 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,32941703 0,33698017 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,32941703 0,33683696 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,33303299 0,34038971 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,33303299 0,34024517 ! rhythmic process GO:0048511 128 75 0,000 0,33303299 0,34010075 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,33303299 0,33995646 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,33662958 0,34348209 ! defense response to bacterium GO:0042742 89 76 0,000 0,33662958 0,34333648 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,33662958 0,343191 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,33662958 0,34304564 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,34020689 0,34654436 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,34020689 0,3463977 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,34020689 0,34625117 ! blood coagulation GO:0007596 146 78 0,000 0,34376503 0,34972459 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,34376503 0,34957678 ! protein oligomerization GO:0051259 139 78 0,000 0,34376503 0,34942909 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3473041 0,35287739 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,3473041 0,35272843 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,3473041 0,3525796 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,35082419 0,35600296 ! inorganic anion transport GO:0015698 138 80 0,000 0,35082419 0,35585287 ! T cell activation GO:0042110 168 81 0,000 0,35432543 0,35925283 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,35432543 0,35910151 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,35432543 0,3589503 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,35432543 0,35879923 ! response to nutrient GO:0007584 125 82 0,000 0,35780789 0,36217324 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,35780789 0,36202093 ! regulation of lyase activity GO:0051339 160 83 0,000 0,36127169 0,36537187 ! hemostasis GO:0007599 158 84 0,000 0,36471691 0,36870122 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,36471691 0,36854636 ! nucleosome assembly GO:0006334 122 85 0,000 0,36814367 0,37185293 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,36814367 0,37169689 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,36814367 0,37154097 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,37155206 0,37482359 ! chromatin assembly GO:0031497 124 86 0,000 0,37155206 0,3746665 ! tube morphogenesis GO:0035239 176 86 0,000 0,37155206 0,37450954 ! alcohol catabolic process GO:0046164 130 86 0,000 0,37155206 0,37435271 ! cellular respiration GO:0045333 135 88 0,000 0,37831412 0,38100618 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,37831412 0,38084676 ! regulation of neurological system process GO:0031644 148 88 0,000 0,37831412 0,38068748 ! cellular defense response GO:0006968 114 89 0,000 0,38166798 0,38390182 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,38166798 0,3837414 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,38500386 0,3869337 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,38832185 0,39010538 ! regulation of defense response GO:0031347 149 92 0,000 0,39162205 0,39325654 ! nucleosome organization GO:0034728 138 92 0,000 0,39162205 0,39309247 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39162205 0,39292855 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,39490456 0,39605684 ! leukocyte differentiation GO:0002521 202 96 0,000 0,40464684 0,40565846 ! mRNA transport GO:0051028 169 96 0,000 0,40464684 0,4054895 ! positive regulation of immune response GO:0050778 156 96 0,000 0,40464684 0,40532069 ! hormone metabolic process GO:0042445 157 97 0,000 0,4078595 0,40836868 ! response to virus GO:0009615 160 98 0,000 0,41105492 0,4113969 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,41423322 0,41440545 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,41423322 0,41423322