pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6313-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 1,382E-06 3,376E-03 ! negative regulation of kinase activity GO:0033673 145 70 5,000 1,505E-06 1,839E-03 ! negative regulation of transferase activity GO:0051348 155 74 5,000 2,092E-06 1,703E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 2,829E-06 1,728E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 3,000 5,11E-06 2,497E-03 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 6,108E-06 2,487E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 6,904E-06 2,409E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 8,526E-06 2,604E-03 GO:0045936|negative regulation of phosphate metabolic process, ! DNA synthesis during DNA repair GO:0000731 18 9 2,000 1,032E-05 2,801E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 1,836E-05 4,485E-03 ! negative regulation of cell growth GO:0030308 142 67 4,000 2,297E-05 5,102E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 2,652E-05 5,398E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,672E-05 5,022E-03 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of cell growth GO:0030307 24 13 2,000 3,461E-05 6,04E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 4,389E-05 7,148E-03 ! nucleus organization GO:0006997 73 40 3,000 4,933E-05 7,532E-03 ! positive regulation of cell size GO:0045793 29 16 2,000 6,702E-05 9,631E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 2,000 6,702E-05 9,096E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 6,702E-05 8,617E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of growth GO:0045926 168 85 4,000 7,252E-05 8,859E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 7,886E-05 9,174E-03 ! activation of MAPKK activity GO:0000186 43 17 2,000 8,108E-05 9,003E-03 ! regulation of survival gene product expression GO:0045884 38 17 2,000 8,108E-05 8,612E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 8,108E-05 8,253E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 8,603E-05 8,407E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,344E-04 0,01263041 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 1,424E-04 0,01288822 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 1,562E-04 0,01363232 ! apoptotic nuclear changes GO:0030262 34 22 2,000 1,802E-04 0,01518412 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,995E-04 0,01624306 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 2,351E-04 0,01853097 ! parathyroid gland development GO:0060017 14 5 1,000 2,497E-04 0,01906317 ! cytokine secretion GO:0050663 15 5 1,000 2,497E-04 0,0184855 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,497E-04 0,0179418 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,497E-04 0,01742918 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 1,000 2,497E-04 0,01694504 ! positive regulation of filopodium assembly GO:0051491 16 5 1,000 2,497E-04 0,01648706 GO:0051489|regulation of filopodium assembly, ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,497E-04 0,01605319 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,497E-04 0,01564157 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,497E-04 0,01525053 ! response to mercury ion GO:0046689 8 5 1,000 2,497E-04 0,01487857 ! decidualization GO:0046697 11 5 1,000 2,497E-04 0,01452432 ! secretory granule organization GO:0033363 15 5 1,000 2,497E-04 0,01418654 ! stem cell division GO:0017145 11 5 1,000 2,497E-04 0,01386412 GO:0048103|somatic stem cell division, ! carnitine metabolic process GO:0009437 8 5 1,000 2,497E-04 0,01355603 GO:0006577|betaine metabolic process, ! vasculogenesis GO:0001570 49 25 2,000 2,662E-04 0,01413875 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 2,662E-04 0,01383793 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 2,998E-04 0,01526038 ! regulation of chromosome organization GO:0033044 49 27 2,000 3,361E-04 0,01675543 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 3,361E-04 0,01642032 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 1,000 3,733E-04 0,01788231 GO:0030816|positive regulation of cAMP metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 3,733E-04 0,01753842 ! activation of MAPKKK activity GO:0000185 12 6 1,000 3,733E-04 0,0172075 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 3,733E-04 0,01688885 ! carnitine transport GO:0015879 10 6 1,000 3,733E-04 0,01658178 GO:0015838|betaine transport, ! establishment of spindle localization GO:0051293 16 6 1,000 3,733E-04 0,01628567 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 3,733E-04 0,01599996 ! triglyceride catabolic process GO:0019433 10 6 1,000 3,733E-04 0,0157241 ! maternal placenta development GO:0001893 12 6 1,000 3,733E-04 0,01545759 ! negative regulation of B cell activation GO:0050869 14 6 1,000 3,733E-04 0,01519996 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 3,75E-04 0,01501871 ! regulation of JUN kinase activity GO:0043506 67 28 2,000 3,75E-04 0,01477648 ! urogenital system development GO:0001655 149 69 3,000 4,165E-04 0,01615147 ! cell cycle checkpoint GO:0000075 145 71 3,000 4,645E-04 0,01773025 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 5,089E-04 0,01912564 ! prostate gland development GO:0030850 14 7 1,000 5,209E-04 0,01928128 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,209E-04 0,0189935 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,209E-04 0,01871418 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 5,209E-04 0,01844296 ! glycerol ether catabolic process GO:0044269 12 7 1,000 5,209E-04 0,01817949 GO:0046464|acylglycerol catabolic process, ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,209E-04 0,01792344 ! anterograde axon cargo transport GO:0008089 18 7 1,000 5,209E-04 0,01767451 ! peptidyl-threonine modification GO:0018210 26 7 1,000 5,209E-04 0,01743239 ! regulation of caspase activity GO:0043281 136 74 3,000 5,436E-04 0,01794746 ! spindle organization GO:0007051 50 32 2,000 5,594E-04 0,01822277 ! triglyceride metabolic process GO:0006641 46 33 2,000 6,131E-04 0,01970832 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 6,319E-04 0,02004967 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 1,000 6,922E-04 0,02168116 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 6,922E-04 0,02140672 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 6,922E-04 0,02113913 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 6,922E-04 0,02087816 ! glycerolipid catabolic process GO:0046503 14 8 1,000 6,922E-04 0,02062354 ! L-phenylalanine metabolic process GO:0006558 12 8 1,000 6,922E-04 0,02037507 GO:0006559|L-phenylalanine catabolic process, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,922E-04 0,02013251 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 6,922E-04 0,01989565 ! intracellular lipid transport GO:0032365 16 8 1,000 6,922E-04 0,01966431 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 6,922E-04 0,01943828 ! mitotic sister chromatid segregation GO:0000070 63 36 2,000 7,935E-04 0,02202881 ! regulation of peptidase activity GO:0052547 150 82 3,000 8,01E-04 0,02198622 ! exocytosis GO:0006887 153 83 3,000 8,383E-04 0,02275384 ! sister chromatid segregation GO:0000819 65 37 2,000 8,603E-04 0,02309677 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 8,603E-04 0,02284572 ! negative regulation of cell activation GO:0050866 69 37 2,000 8,603E-04 0,02260007 ! neutral lipid catabolic process GO:0046461 14 9 1,000 8,871E-04 0,02305435 ! artery development GO:0060840 25 9 1,000 8,871E-04 0,02281168 GO:0048844|artery morphogenesis, ! middle ear morphogenesis GO:0042474 14 9 1,000 8,871E-04 0,02257405 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 1,000 8,871E-04 0,02234133 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 8,871E-04 0,02211336 ! S phase GO:0051320 10 9 1,000 8,871E-04 0,02188999 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 16 9 1,000 8,871E-04 0,02167109 ! regulation of telomere maintenance GO:0032204 17 9 1,000 8,871E-04 0,02145653 ! neutral lipid metabolic process GO:0006638 54 38 2,000 9,306E-04 0,02228973 GO:0006639|acylglycerol metabolic process, ! mitochondrion organization GO:0007005 159 87 3,000 9,996E-04 0,02371014 ! glycerol ether metabolic process GO:0006662 57 40 2,000 1,082E-03 0,02541479 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,105E-03 0,0257135 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,105E-03 0,02547092 ! phospholipid efflux GO:0033700 19 10 1,000 1,105E-03 0,02523288 ! positive regulation of survival gene product expression GO:0045885 26 10 1,000 1,105E-03 0,02499924 ! reverse cholesterol transport GO:0043691 19 10 1,000 1,105E-03 0,02476989 ! phagocytosis, engulfment GO:0006911 33 10 1,000 1,105E-03 0,02454471 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,105E-03 0,02432359 ! motor axon guidance GO:0008045 22 10 1,000 1,105E-03 0,02410641 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 1,000 1,105E-03 0,02389308 ! quaternary ammonium group transport GO:0015697 22 10 1,000 1,105E-03 0,02368349 ! blastocyst formation GO:0001825 18 10 1,000 1,105E-03 0,02347755 ! regulation of cell cycle process GO:0010564 161 90 3,000 1,134E-03 0,02388655 ! gland development GO:0048732 220 91 3,000 1,182E-03 0,0246749 ! regulation of cell adhesion GO:0030155 241 92 3,000 1,231E-03 0,02547842 ! ear morphogenesis GO:0042471 64 42 2,000 1,248E-03 0,02561851 ! organic ether metabolic process GO:0018904 59 42 2,000 1,248E-03 0,02540502 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,248E-03 0,02519506 ! cytokinesis GO:0000910 84 42 2,000 1,248E-03 0,02498854 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,281E-03 0,02544196 ! epithelial cell differentiation GO:0030855 83 43 2,000 1,337E-03 0,02633214 ! development of primary male sexual characteristics GO:0046546 80 43 2,000 1,337E-03 0,02612148 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,337E-03 0,02591417 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,346E-03 0,02589747 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,346E-03 0,02569515 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,346E-03 0,02549596 GO:0010812|negative regulation of cell-substrate adhesion, ! thymus development GO:0048538 29 11 1,000 1,346E-03 0,02529984 ! cholesterol efflux GO:0033344 21 11 1,000 1,346E-03 0,02510671 ! germ cell migration GO:0008354 26 11 1,000 1,346E-03 0,02491651 ! regulation of embryonic development GO:0045995 35 11 1,000 1,346E-03 0,02472916 ! sex differentiation GO:0007548 171 96 3,000 1,44E-03 0,02626202 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,61E-03 0,02913865 ! regulation of cell projection assembly GO:0060491 33 12 1,000 1,61E-03 0,0289244 ! drug transport GO:0015893 16 12 1,000 1,61E-03 0,02871327 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,61E-03 0,0285052 ! tyrosine metabolic process GO:0006570 19 12 1,000 1,61E-03 0,02830013 ! focal adhesion formation GO:0048041 37 12 1,000 1,61E-03 0,02809798 ! embryonic placenta development GO:0001892 21 12 1,000 1,61E-03 0,02789871 ! pigmentation GO:0043473 103 46 2,000 1,626E-03 0,02797299 ! cell growth GO:0016049 90 46 2,000 1,626E-03 0,02777737 ! regulation of JNK cascade GO:0046328 104 47 2,000 1,73E-03 0,02935689 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,839E-03 0,03098373 ! cellular component disassembly GO:0022411 89 48 2,000 1,839E-03 0,03077151 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 1,839E-03 0,03056218 ! male sex differentiation GO:0046661 93 48 2,000 1,839E-03 0,03035568 ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 1,897E-03 0,03109776 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,952E-03 0,031787 ! JNK cascade GO:0007254 106 49 2,000 1,952E-03 0,03157649 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,952E-03 0,03136875 ! activation of caspase activity GO:0006919 95 50 2,000 2,069E-03 0,03303108 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 2,000 2,19E-03 0,03473954 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,19E-03 0,03451541 ! palate development GO:0060021 32 14 1,000 2,205E-03 0,03453819 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 2,205E-03 0,0343182 ! negative regulation of caspase activity GO:0043154 23 14 1,000 2,205E-03 0,034101 ! bone mineralization GO:0030282 18 14 1,000 2,205E-03 0,03388653 ! male genitalia development GO:0030539 26 14 1,000 2,205E-03 0,03367474 ! positive regulation of growth GO:0045927 96 53 2,000 2,445E-03 0,03710534 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,445E-03 0,03687629 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of mRNA processing GO:0050684 26 15 1,000 2,536E-03 0,03801431 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,536E-03 0,03778252 ! cofactor transport GO:0051181 30 15 1,000 2,536E-03 0,03755353 ! regulation of angiogenesis GO:0045765 125 54 2,000 2,58E-03 0,03796475 ! response to UV GO:0009411 120 55 2,000 2,718E-03 0,03976809 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 2,889E-03 0,0420127 ! axon cargo transport GO:0008088 46 16 1,000 2,889E-03 0,04176411 ! neuron recognition GO:0008038 40 16 1,000 2,889E-03 0,04151843 ! biomineral formation GO:0031214 22 16 1,000 2,889E-03 0,04127564 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,01E-03 0,04274875 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 2,000 3,01E-03 0,04250165 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,264E-03 0,04582074 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 3,264E-03 0,04555891 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,264E-03 0,04530005 ! genitalia development GO:0048806 32 17 1,000 3,264E-03 0,04504412 ! organic cation transport GO:0015695 32 17 1,000 3,264E-03 0,04479106 ! DNA catabolic process GO:0006308 94 60 2,000 3,481E-03 0,04751368 ! kidney development GO:0001822 133 60 2,000 3,481E-03 0,04724971 ! cell-substrate junction assembly GO:0007044 56 18 1,000 3,659E-03 0,04939121 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 3,819E-03 0,0512688 ! regulation of mitosis GO:0007088 112 63 2,000 3,996E-03 0,05334197 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 2,000 3,996E-03 0,05305207 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,076E-03 0,05383021 ! pigmentation during development GO:0048066 42 19 1,000 4,076E-03 0,0535408 ! neuromuscular junction development GO:0007528 43 19 1,000 4,076E-03 0,05325449 ! vitamin transport GO:0051180 31 19 1,000 4,076E-03 0,05297122 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,363E-03 0,05639542 ! protein secretion GO:0009306 45 20 1,000 4,514E-03 0,05804533 ! skin development GO:0043588 42 20 1,000 4,514E-03 0,05774142 ! response to alkaloid GO:0043279 38 20 1,000 4,514E-03 0,05744069 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 4,514E-03 0,05714307 ! actin filament bundle formation GO:0051017 47 20 1,000 4,514E-03 0,05684851 ! body fluid secretion GO:0007589 33 20 1,000 4,514E-03 0,05655698 ! peptide secretion GO:0002790 38 20 1,000 4,514E-03 0,05626843 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 4,514E-03 0,0559828 ! aromatic compound catabolic process GO:0019439 31 20 1,000 4,514E-03 0,05570006 ! negative regulation of translation GO:0017148 32 20 1,000 4,514E-03 0,05542016 ! ear development GO:0043583 114 66 2,000 4,554E-03 0,0556271 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 4,554E-03 0,05535035 ! chromosome segregation GO:0007059 127 67 2,000 4,75E-03 0,05744704 ! regulation of cellular response to stress GO:0080135 142 68 2,000 4,951E-03 0,0595836 ! extracellular matrix organization GO:0030198 146 68 2,000 4,951E-03 0,05929153 ! collagen fibril organization GO:0030199 62 21 1,000 4,973E-03 0,05926507 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 4,973E-03 0,05897737 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 4,973E-03 0,05869246 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 5,452E-03 0,06403961 ! microtubule-based transport GO:0010970 59 22 1,000 5,452E-03 0,0637332 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 5,452E-03 0,06342971 ! central nervous system neuron development GO:0021954 47 22 1,000 5,452E-03 0,06312909 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 5,452E-03 0,06283132 ! G1 phase GO:0051318 44 22 1,000 5,452E-03 0,06253633 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 5,452E-03 0,06224411 ! peptidyl-serine modification GO:0018209 50 22 1,000 5,452E-03 0,0619546 ! response to cytokine stimulus GO:0034097 69 22 1,000 5,452E-03 0,06166777 ! activation of JUN kinase activity GO:0007257 47 22 1,000 5,452E-03 0,06138359 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,452E-03 0,06110201 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 5,585E-03 0,06229934 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 5,806E-03 0,064476 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,952E-03 0,0657954 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 5,952E-03 0,06549903 ! gluconeogenesis GO:0006094 38 23 1,000 5,952E-03 0,06520531 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 5,952E-03 0,06491421 GO:0010810|regulation of cell-substrate adhesion, ! lysosome organization GO:0007040 47 23 1,000 5,952E-03 0,06462571 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 6,472E-03 0,06995774 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 6,472E-03 0,06964956 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 6,472E-03 0,06934408 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 6,472E-03 0,06904126 ! sex determination GO:0007530 48 24 1,000 6,472E-03 0,06874108 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 6,472E-03 0,0684435 ! reproductive structure development GO:0048608 131 75 2,000 6,502E-03 0,06846859 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 6,502E-03 0,06817473 ! axon guidance GO:0007411 162 75 2,000 6,502E-03 0,06788339 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 7,011E-03 0,07288815 ! vacuole organization GO:0007033 49 25 1,000 7,011E-03 0,07257931 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 7,504E-03 0,07735267 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 7,504E-03 0,07702765 ! myelination GO:0042552 50 26 1,000 7,571E-03 0,07738522 ! pyruvate metabolic process GO:0006090 43 26 1,000 7,571E-03 0,07706278 ! positive regulation of nuclear division GO:0051785 41 26 1,000 7,571E-03 0,07674302 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 50 26 1,000 7,571E-03 0,0764259 ! telomere organization GO:0032200 46 26 1,000 7,571E-03 0,07611139 GO:0000723|telomere maintenance, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 7,571E-03 0,07579946 ! activation of protein kinase activity GO:0032147 170 80 2,000 7,768E-03 0,07745861 ! development of primary sexual characteristics GO:0045137 143 80 2,000 7,768E-03 0,07714374 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 8,149E-03 0,08060321 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 8,149E-03 0,08027819 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 8,149E-03 0,07995579 ! response to drug GO:0042493 149 83 2,000 8,592E-03 0,08396575 ! cellular lipid catabolic process GO:0044242 150 83 2,000 8,592E-03 0,08363122 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 8,747E-03 0,08480151 ! neuron fate commitment GO:0048663 52 28 1,000 8,747E-03 0,08446633 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 8,747E-03 0,08413378 ! negative regulation of protein modification process GO:0031400 66 28 1,000 8,747E-03 0,08380384 ! base-excision repair GO:0006284 41 28 1,000 8,747E-03 0,08347649 ! lipid oxidation GO:0034440 48 28 1,000 8,747E-03 0,08315167 GO:0019395|fatty acid oxidation, ! regulation of ligase activity GO:0051340 147 84 2,000 8,878E-03 0,0840681 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 9,365E-03 0,08833023 ! response to organic cyclic substance GO:0014070 58 29 1,000 9,365E-03 0,0879905 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 9,365E-03 0,08765337 ! phospholipid transport GO:0015914 65 30 1,000 0,01000047 0,09324861 ! neurotransmitter secretion GO:0007269 55 30 1,000 0,01000047 0,09289406 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01000047 0,09254218 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 0,01000047 0,09219297 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01000047 0,09184638 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01039026 0,09506897 ! cell junction assembly GO:0034329 85 31 1,000 0,01065506 0,09712801 ! peptide transport GO:0015833 60 31 1,000 0,01065506 0,09676694 ! male gonad development GO:0008584 56 31 1,000 0,01065506 0,09640854 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01065506 0,09605279 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01065506 0,09569966 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01065506 0,09534911 GO:0008366|axon ensheathment, ! fatty acid catabolic process GO:0009062 54 31 1,000 0,01065506 0,09500112 ! response to heat GO:0009408 54 31 1,000 0,01065506 0,09465566 ! metanephros development GO:0001656 81 32 1,000 0,0113281 0,1002701 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,0113281 0,09990811 ! hexose biosynthetic process GO:0019319 53 32 1,000 0,0113281 0,09954873 ! peripheral nervous system development GO:0007422 68 32 1,000 0,0113281 0,09919192 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,0113281 0,09883767 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,01201939 0,10449597 GO:0055092|sterol homeostasis, ! response to ionizing radiation GO:0010212 74 33 1,000 0,01201939 0,10412542 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,01201939 0,10375748 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01201939 0,10339214 ! glial cell differentiation GO:0010001 67 34 1,000 0,01272873 0,10910976 ! post-embryonic development GO:0009791 76 34 1,000 0,01272873 0,10872826 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,01272873 0,10834942 ! cholesterol transport GO:0030301 62 34 1,000 0,01272873 0,1079732 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01272873 0,10759959 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01274336 0,10735179 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,0131023 0,10999624 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01345592 0,11257812 ! sterol transport GO:0015918 63 35 1,000 0,01345592 0,11219389 ! placenta development GO:0001890 53 35 1,000 0,01345592 0,11181228 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01420077 0,11760161 ! positive regulation of cell development GO:0010720 85 36 1,000 0,01420077 0,1172043 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01420077 0,11680968 ! cytokine production GO:0001816 68 36 1,000 0,01420077 0,1164177 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01420077 0,11602834 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01496308 0,12184933 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01496308 0,12144451 ! odontogenesis GO:0042476 74 37 1,000 0,01496308 0,12104238 ! cell junction organization GO:0034330 96 37 1,000 0,01496308 0,1206429 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01496308 0,12024604 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01574266 0,1260961 ! meiosis I GO:0007127 74 38 1,000 0,01574266 0,12568402 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01574266 0,12527463 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01574266 0,12486789 ! regulation of protein stability GO:0031647 77 38 1,000 0,01574266 0,12446379 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01574266 0,12406229 ! negative regulation of binding GO:0051100 71 39 1,000 0,01653932 0,12992137 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01653932 0,12950496 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01653932 0,12909121 ! mammary gland development GO:0030879 93 40 1,000 0,01735286 0,13500969 ! learning GO:0007612 82 40 1,000 0,01735286 0,13458109 ! lipid homeostasis GO:0055088 75 40 1,000 0,01735286 0,1341552 ! mismatch repair GO:0006298 58 40 1,000 0,01735286 0,133732 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01735286 0,13331146 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,01735286 0,13289355 ! gliogenesis GO:0042063 91 41 1,000 0,01818311 0,13881668 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 1,000 0,01818311 0,13838423 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 1,000 0,01818311 0,13795446 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,01902987 0,14393181 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01902987 0,14348757 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,01902987 0,14304607 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01989296 0,14907515 ! glucose transport GO:0015758 66 43 1,000 0,01989296 0,14861927 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01989296 0,14816616 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,01989296 0,14771581 ! ion transmembrane transport GO:0034220 79 43 1,000 0,01989296 0,14726818 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,01989296 0,14682326 ! hexose transport GO:0008645 68 44 1,000 0,02077219 0,1528508 GO:0015749|monosaccharide transport, ! phagocytosis GO:0006909 105 44 1,000 0,02077219 0,15239179 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02166739 0,15848331 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,02166739 0,15801023 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02166739 0,15753996 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,02257836 0,16367638 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02257836 0,16319213 ! response to insulin stimulus GO:0032868 98 47 1,000 0,02350494 0,16938809 ! endosome transport GO:0016197 127 48 1,000 0,02444694 0,17565842 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02492911 0,17859768 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02492911 0,17807546 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02492911 0,17755629 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02492911 0,17704014 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02492911 0,17652698 ! neuron fate determination GO:0048664 7 5 0,000 0,02492911 0,17601679 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02492911 0,17550953 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02492911 0,1750052 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02492911 0,17450375 ! polyol transport GO:0015791 12 5 0,000 0,02492911 0,17400517 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02492911 0,17350943 ! response to superoxide GO:0000303 10 5 0,000 0,02492911 0,1730165 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02492911 0,17252637 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02492911 0,17203901 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02492911 0,17155439 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02492911 0,1710725 ! female meiosis GO:0007143 10 5 0,000 0,02492911 0,1705933 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02492911 0,17011678 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02492911 0,16964292 ! hypothalamus development GO:0021854 9 5 0,000 0,02492911 0,16917169 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02492911 0,16870307 ! cobalt ion transport GO:0006824 11 5 0,000 0,02492911 0,16823704 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02492911 0,16777358 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02492911 0,16731266 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02492911 0,16685427 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02492911 0,16639838 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02492911 0,16594498 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02492911 0,16549404 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02492911 0,16504555 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02492911 0,16459948 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02492911 0,16415582 ! transposition GO:0032196 9 5 0,000 0,02492911 0,16371454 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02492911 0,16327563 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02492911 0,16283906 ! negative chemotaxis GO:0050919 16 5 0,000 0,02492911 0,16240482 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02492911 0,16197289 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02492911 0,16154326 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02492911 0,1611159 ! behavioral response to pain GO:0048266 10 5 0,000 0,02492911 0,16069079 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02492911 0,16026792 ! Notch receptor processing GO:0007220 11 5 0,000 0,02492911 0,15984727 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02492911 0,15942882 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02492911 0,15901255 ! micturition GO:0060073 9 5 0,000 0,02492911 0,15859846 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02492911 0,15818652 ! copulation GO:0007620 9 5 0,000 0,02492911 0,15777671 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02492911 0,15736901 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02492911 0,15696342 ! bioluminescence GO:0008218 9 5 0,000 0,02492911 0,15655992 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02492911 0,15615848 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02492911 0,1557591 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02492911 0,15536176 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02492911 0,15496643 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02492911 0,15457312 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02492911 0,15418179 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02492911 0,15379245 ! grooming behavior GO:0007625 6 5 0,000 0,02492911 0,15340506 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02492911 0,15301962 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02492911 0,15263611 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02492911 0,15225452 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02492911 0,15187483 ! response to protozoan GO:0001562 13 5 0,000 0,02492911 0,15149704 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02492911 0,15112111 ! lymph vessel development GO:0001945 10 5 0,000 0,02492911 0,15074705 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02492911 0,15037484 ! endochondral ossification GO:0001958 17 5 0,000 0,02492911 0,15000445 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02492911 0,14963589 ! single strand break repair GO:0000012 8 5 0,000 0,02492911 0,14926914 ! anagen GO:0042640 7 5 0,000 0,02492911 0,14890418 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02492911 0,148541 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02492911 0,14817958 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02492911 0,14781992 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02492911 0,14746201 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02492911 0,14710582 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02492911 0,14675135 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02492911 0,14639858 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02492911 0,1460475 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02492911 0,14569811 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02492911 0,14535038 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02492911 0,14500431 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02492911 0,14465988 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02492911 0,14431708 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02492911 0,14397591 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02492911 0,14363634 ! microvillus organization GO:0032528 8 5 0,000 0,02492911 0,14329837 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02492911 0,14296199 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02492911 0,14262719 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02492911 0,14229394 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02492911 0,14196226 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02492911 0,14163211 ! polyol catabolic process GO:0046174 9 5 0,000 0,02492911 0,1413035 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02492911 0,14097641 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02492911 0,14065083 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02492911 0,14032675 ! muscle cell migration GO:0014812 8 5 0,000 0,02492911 0,14000416 ! mitochondrial fission GO:0000266 8 5 0,000 0,02492911 0,13968305 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02492911 0,13936341 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02492911 0,13904522 ! mRNA transcription GO:0009299 10 5 0,000 0,02492911 0,13872849 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02492911 0,1384132 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02492911 0,13809934 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02492911 0,1377869 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02492911 0,13747587 ! monocyte activation GO:0042117 10 5 0,000 0,02492911 0,13716624 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02492911 0,136858 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02492911 0,13655114 ! response to food GO:0032094 6 5 0,000 0,02492911 0,13624566 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02492911 0,13594154 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02492911 0,13563877 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02492911 0,13533735 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02492911 0,13503727 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02492911 0,13473851 ! forebrain neuron development GO:0021884 13 5 0,000 0,02492911 0,13444108 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02492911 0,13414495 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02492911 0,13385013 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02492911 0,1335566 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02492911 0,13326435 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02492911 0,13297338 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02492911 0,13268368 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02492911 0,13239524 ! lipid glycosylation GO:0030259 7 5 0,000 0,02492911 0,13210804 ! nucleobase transport GO:0015851 6 5 0,000 0,02492911 0,1318221 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02492911 0,13153738 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02492911 0,1312539 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02492911 0,13097163 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02492911 0,13069058 ! basic amino acid transport GO:0015802 12 5 0,000 0,02492911 0,13041072 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02492911 0,13013207 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02492911 0,1298546 ! actin nucleation GO:0045010 11 5 0,000 0,02492911 0,12957832 ! depurination GO:0045007 5 5 0,000 0,02492911 0,1293032 ! depyrimidination GO:0045008 10 5 0,000 0,02492911 0,12902926 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02492911 0,12875647 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02492911 0,12848483 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02492911 0,12821433 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02492911 0,12794498 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02492911 0,12767675 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02492911 0,12740964 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02492911 0,12714365 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02492911 0,12687877 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02492911 0,12661499 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02492911 0,1263523 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02492911 0,1260907 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02492911 0,12583018 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02492911 0,12557074 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02492911 0,12531236 ! response to arsenic GO:0046685 11 5 0,000 0,02492911 0,12505505 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02492911 0,12479879 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02492911 0,12454358 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02492911 0,1242894 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02492911 0,12403627 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02492911 0,12378416 ! response to cadmium ion GO:0046686 7 5 0,000 0,02492911 0,12353308 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02492911 0,12328301 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02492911 0,12303396 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02492911 0,1227859 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02492911 0,12253885 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02492911 0,12229279 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02492911 0,12204771 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02492911 0,12180362 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02492911 0,1215605 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02492911 0,12131834 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02492911 0,12107715 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02492911 0,12083692 ! embryonic cleavage GO:0040016 6 5 0,000 0,02492911 0,12059764 ! peroxisome fission GO:0016559 5 5 0,000 0,02492911 0,12035931 ! histone demethylation GO:0016577 13 5 0,000 0,02492911 0,12012191 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02492911 0,11988545 ! mitotic recombination GO:0006312 9 5 0,000 0,02492911 0,11964992 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02492911 0,11941531 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02492911 0,11918162 ! metaphase plate congression GO:0051310 7 5 0,000 0,02492911 0,11894884 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02492911 0,11871698 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02492911 0,11848601 ! enteric nervous system development GO:0048484 8 5 0,000 0,02492911 0,11825594 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02492911 0,11802676 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02492911 0,11779847 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02492911 0,11757106 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02492911 0,11734452 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02492911 0,11711886 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02492911 0,11689407 ! B cell homeostasis GO:0001782 13 5 0,000 0,02492911 0,11667013 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02492911 0,11644705 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02492911 0,11622483 ! metaphase GO:0051323 11 5 0,000 0,02492911 0,11600344 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02492911 0,11578291 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02492911 0,1155632 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02492911 0,11534433 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02492911 0,11512629 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02492911 0,11490907 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02492911 0,11469267 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02492911 0,11447708 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02492911 0,1142623 ! response to redox state GO:0051775 6 5 0,000 0,02492911 0,11404833 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02492911 0,11383516 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02492911 0,11362278 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02492911 0,11341119 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02492911 0,11320039 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02492911 0,11299037 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02492911 0,11278113 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02492911 0,11257266 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02492911 0,11236496 ! striatum development GO:0021756 14 5 0,000 0,02492911 0,11215803 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02492911 0,11195185 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02492911 0,11174644 ! glial cell migration GO:0008347 10 5 0,000 0,02492911 0,11154177 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02492911 0,11133786 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02492911 0,11113469 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02492911 0,11093226 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02492911 0,11073056 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02492911 0,1105296 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02492911 0,11032936 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02492911 0,11012985 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02492911 0,10993106 ! neuroprotection GO:0043526 8 5 0,000 0,02492911 0,10973299 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02492911 0,10953563 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02492911 0,10933897 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02492911 0,10914303 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02492911 0,10894778 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02492911 0,10875323 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02492911 0,10855937 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02492911 0,10836621 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02492911 0,10817373 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02492911 0,10798193 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02492911 0,10779081 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02492911 0,10760037 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02492911 0,1074106 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02492911 0,10722149 ! spindle assembly GO:0051225 6 5 0,000 0,02492911 0,10703306 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02492911 0,10684528 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02492911 0,10665816 ! protein palmitoylation GO:0018345 12 5 0,000 0,02492911 0,10647169 ! drug metabolic process GO:0017144 7 5 0,000 0,02492911 0,10628588 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02492911 0,10610071 ! organ regeneration GO:0031100 7 5 0,000 0,02492911 0,10591619 ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02492911 0,10573231 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02540418 0,1075605 ! regulation of action potential GO:0001508 102 50 1,000 0,02637649 0,11148403 ! endocrine system development GO:0035270 109 50 1,000 0,02637649 0,11129148 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02637649 0,1110996 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,0273637 0,11505941 ! response to temperature stimulus GO:0009266 84 51 1,000 0,0273637 0,11486172 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,0273637 0,1146647 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,02836563 0,11865965 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,02836563 0,11845682 ! inner ear development GO:0048839 89 53 1,000 0,02938211 0,12249233 ! vesicle organization GO:0016050 127 53 1,000 0,02938211 0,12228365 ! synapse organization GO:0050808 102 53 1,000 0,02938211 0,12207569 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02984027 0,12376871 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02984027 0,12355893 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02984027 0,12334987 ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02984027 0,1231415 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02984027 0,12293385 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02984027 0,12272689 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02984027 0,12252062 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02984027 0,12231505 ! response to oxygen radical GO:0000305 11 6 0,000 0,02984027 0,12211017 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02984027 0,12190597 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02984027 0,12170245 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02984027 0,12149962 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02984027 0,12129746 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02984027 0,12109596 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02984027 0,12089514 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02984027 0,12069498 ! forebrain regionalization GO:0021871 9 6 0,000 0,02984027 0,12049549 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02984027 0,12029665 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02984027 0,12009847 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02984027 0,11990094 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02984027 0,11970406 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02984027 0,11950782 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02984027 0,11931223 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02984027 0,11911727 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02984027 0,11892295 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02984027 0,11872927 ! malate metabolic process GO:0006108 13 6 0,000 0,02984027 0,11853621 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02984027 0,11834378 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02984027 0,11815198 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02984027 0,11796079 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02984027 0,11777023 ! protein refolding GO:0042026 15 6 0,000 0,02984027 0,11758028 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02984027 0,11739093 ! opsonization GO:0008228 8 6 0,000 0,02984027 0,1172022 ! mating behavior GO:0007617 7 6 0,000 0,02984027 0,11701408 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02984027 0,11682656 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02984027 0,11663963 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02984027 0,11645331 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02984027 0,11626758 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02984027 0,11608244 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02984027 0,11589789 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02984027 0,11571392 ! toxin metabolic process GO:0009404 11 6 0,000 0,02984027 0,11553054 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02984027 0,11534774 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02984027 0,11516551 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02984027 0,11498387 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02984027 0,11480279 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02984027 0,11462228 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02984027 0,11444234 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02984027 0,11426296 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02984027 0,11408415 ! thymic T cell selection GO:0045061 16 6 0,000 0,02984027 0,11390589 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02984027 0,11372819 ! protein lipoylation GO:0009249 10 6 0,000 0,02984027 0,11355104 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02984027 0,11337445 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02984027 0,1131984 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02984027 0,1130229 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02984027 0,11284794 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02984027 0,11267352 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02984027 0,11249965 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02984027 0,1123263 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02984027 0,11215349 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02984027 0,11198121 ! hyperosmotic response GO:0006972 10 6 0,000 0,02984027 0,11180946 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02984027 0,11163824 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02984027 0,11146754 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02984027 0,11129736 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02984027 0,1111277 ! urea metabolic process GO:0019627 7 6 0,000 0,02984027 0,11095855 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02984027 0,11078992 ! neutrophil activation GO:0042119 7 6 0,000 0,02984027 0,11062181 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02984027 0,1104542 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02984027 0,1102871 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02984027 0,1101205 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02984027 0,10995441 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02984027 0,10978881 ! neuron apoptosis GO:0051402 15 6 0,000 0,02984027 0,10962372 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02984027 0,10945911 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02984027 0,10929501 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02984027 0,10913139 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02984027 0,10896827 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02984027 0,10880563 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02984027 0,10864347 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02984027 0,1084818 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02984027 0,10832061 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02984027 0,1081599 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02984027 0,10799966 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02984027 0,1078399 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02984027 0,10768061 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02984027 0,10752179 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02984027 0,10736343 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02984027 0,10720554 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02984027 0,10704812 ! response to UV-C GO:0010225 14 6 0,000 0,02984027 0,10689116 ! astrocyte development GO:0014002 16 6 0,000 0,02984027 0,10673466 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02984027 0,10657861 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02984027 0,10642302 ! interaction with symbiont GO:0051702 14 6 0,000 0,02984027 0,10626789 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02984027 0,1061132 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02984027 0,10595897 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02984027 0,10580518 ! response to copper ion GO:0046688 10 6 0,000 0,02984027 0,10565184 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02984027 0,10549894 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02984027 0,10534649 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02984027 0,10519447 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02984027 0,1050429 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02984027 0,10489176 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02984027 0,10474105 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02984027 0,10459078 ! hair follicle maturation GO:0048820 8 6 0,000 0,02984027 0,10444093 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02984027 0,10429152 ! Schwann cell development GO:0014044 15 6 0,000 0,02984027 0,10414253 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02984027 0,10399397 ! response to pheromone GO:0019236 6 6 0,000 0,02984027 0,10384583 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02984027 0,10369811 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02984027 0,10355081 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02984027 0,10340393 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02984027 0,10325747 ! subpallium development GO:0021544 15 6 0,000 0,02984027 0,10311142 ! neural tube patterning GO:0021532 8 6 0,000 0,02984027 0,10296578 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02984027 0,10282055 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02984027 0,10267573 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02984027 0,10253132 ! G2 phase GO:0051319 16 6 0,000 0,02984027 0,10238732 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02984027 0,10224372 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02984027 0,10210052 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02984027 0,10195772 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02984027 0,10181532 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02984027 0,10167332 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02984027 0,10153171 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02984027 0,1013905 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02984027 0,10124968 ! receptor internalization GO:0031623 11 6 0,000 0,02984027 0,10110925 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02984027 0,10096921 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02984027 0,10082956 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02984027 0,10069029 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02984027 0,10055141 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02984027 0,10041291 ! protein deubiquitination GO:0016579 16 6 0,000 0,02984027 0,10027479 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02984027 0,10013705 ! protein destabilization GO:0031648 9 6 0,000 0,02984027 0,09999969 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02984027 0,0998627 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02984027 0,09972609 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02984027 0,09958985 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02984027 0,09945398 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02984027 0,09931849 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02984027 0,09918336 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02984027 0,0990486 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02984027 0,09891421 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02984027 0,09878018 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02984027 0,09864651 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02984027 0,0985132 ! neural plate development GO:0001840 9 6 0,000 0,02984027 0,09838026 ! catecholamine transport GO:0051937 9 6 0,000 0,02984027 0,09824767 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02984027 0,09811544 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02984027 0,09798356 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02984027 0,09785204 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02984027 0,09772087 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02984027 0,09759005 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02984027 0,09745959 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02984027 0,09732947 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02984027 0,09719969 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02984027 0,09707027 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02984027 0,09694118 GO:0055081|anion homeostasis, ! protein amino acid lipidation GO:0006497 109 54 1,000 0,03041298 0,09867052 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03041298 0,09853966 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,03041298 0,09840914 ! cell recognition GO:0008037 98 55 1,000 0,03145805 0,10165611 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03145805 0,10152182 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03251717 0,10480138 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03251717 0,10466331 ! regulation of DNA replication GO:0006275 105 56 1,000 0,03251717 0,10452559 ! muscle fiber development GO:0048747 131 57 1,000 0,03359017 0,10783283 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,03359017 0,10769131 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,03467688 0,11102964 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,03467688 0,11088431 ! aging GO:0007568 112 58 1,000 0,03467688 0,11073937 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03467688 0,1105948 ! maintenance of location GO:0051235 124 58 1,000 0,03467688 0,11045061 ! tRNA transcription GO:0009304 17 7 0,000 0,03472683 0,11046567 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03472683 0,11032203 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03472683 0,11017875 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03472683 0,11003585 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03472683 0,10989331 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03472683 0,10975115 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03472683 0,10960935 ! sleep GO:0030431 16 7 0,000 0,03472683 0,10946792 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03472683 0,10932685 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03472683 0,10918615 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03472683 0,10904581 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03472683 0,10890583 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03472683 0,1087662 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03472683 0,10862694 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03472683 0,10848803 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03472683 0,10834947 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03472683 0,10821127 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03472683 0,10807342 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03472683 0,10793593 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03472683 0,10779878 ! glycolipid transport GO:0046836 11 7 0,000 0,03472683 0,10766198 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03472683 0,10752552 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03472683 0,10738942 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03472683 0,10725365 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03472683 0,10711823 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03472683 0,10698315 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03472683 0,10684841 ! mRNA stabilization GO:0048255 18 7 0,000 0,03472683 0,10671401 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03472683 0,10657995 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03472683 0,10644622 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03472683 0,10631283 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03472683 0,10617977 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03472683 0,10604705 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03472683 0,10591465 ! lipoprotein transport GO:0042953 14 7 0,000 0,03472683 0,10578259 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03472683 0,10565086 ! rhythmic behavior GO:0007622 17 7 0,000 0,03472683 0,10551945 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03472683 0,10538837 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03472683 0,10525762 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03472683 0,10512718 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03472683 0,10499708 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03472683 0,10486729 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03472683 0,10473782 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03472683 0,10460868 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03472683 0,10447985 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03472683 0,10435134 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03472683 0,10422314 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03472683 0,10409526 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03472683 0,10396769 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03472683 0,10384044 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03472683 0,10371349 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03472683 0,10358686 ! spinal cord patterning GO:0021511 14 7 0,000 0,03472683 0,10346053 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03472683 0,10333452 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03472683 0,10320881 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03472683 0,1030834 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03472683 0,1029583 ! adrenal gland development GO:0030325 17 7 0,000 0,03472683 0,1028335 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03472683 0,10270901 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03472683 0,10258481 ! ovulation GO:0030728 10 7 0,000 0,03472683 0,10246092 ! adenohypophysis development GO:0021984 11 7 0,000 0,03472683 0,10233732 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03472683 0,10221402 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03472683 0,10209102 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03472683 0,10196832 ! microtubule nucleation GO:0007020 21 7 0,000 0,03472683 0,1018459 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03472683 0,10172379 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03472683 0,10160196 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03472683 0,10148043 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03472683 0,10135919 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03472683 0,10123823 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03472683 0,10111757 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03472683 0,10099719 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03472683 0,1008771 ! galactose metabolic process GO:0006012 13 7 0,000 0,03472683 0,10075729 ! vesicle fusion GO:0006906 20 7 0,000 0,03472683 0,10063777 ! response to dietary excess GO:0002021 8 7 0,000 0,03472683 0,10051853 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03472683 0,10039957 GO:0045851|pH reduction, ! melanosome organization GO:0032438 10 7 0,000 0,03472683 0,1002809 ! organ growth GO:0035265 15 7 0,000 0,03472683 0,1001625 ! nucleoside transport GO:0015858 11 7 0,000 0,03472683 0,10004438 ! nucleoside salvage GO:0043174 11 7 0,000 0,03472683 0,09992655 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03472683 0,09980899 ! male sex determination GO:0030238 15 7 0,000 0,03472683 0,0996917 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03472683 0,09957469 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03472683 0,09945796 ! parturition GO:0007567 16 7 0,000 0,03472683 0,0993415 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03472683 0,09922531 ! rRNA modification GO:0000154 14 7 0,000 0,03472683 0,09910939 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03472683 0,09899374 ! spindle checkpoint GO:0031577 16 7 0,000 0,03472683 0,09887837 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03472683 0,09876326 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03472683 0,09864842 ! monocyte differentiation GO:0030224 16 7 0,000 0,03472683 0,09853384 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03472683 0,09841953 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03472683 0,09830549 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03472683 0,09819171 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03472683 0,09807819 ! fibrinolysis GO:0042730 11 7 0,000 0,03472683 0,09796494 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03472683 0,09785195 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03472683 0,09773921 ! eating behavior GO:0042755 8 7 0,000 0,03472683 0,09762674 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03472683 0,09751453 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03472683 0,09740257 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03472683 0,09729087 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03472683 0,09717943 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03472683 0,09706824 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03472683 0,0969573 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03472683 0,09684662 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03472683 0,09673619 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03472683 0,09662601 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03472683 0,09651608 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03472683 0,09640641 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03472683 0,09629698 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03472683 0,0961878 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03472683 0,09607887 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03472683 0,09597018 ! histone ubiquitination GO:0016574 9 7 0,000 0,03472683 0,09586174 ! regulation of meiosis GO:0040020 12 7 0,000 0,03472683 0,09575354 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03472683 0,09564559 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03472683 0,09553788 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03472683 0,09543041 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03472683 0,09532319 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03472683 0,0952162 ! transcription termination GO:0006353 14 7 0,000 0,03472683 0,09510946 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03472683 0,09500295 ! anaphase GO:0051322 18 7 0,000 0,03472683 0,09489669 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03472683 0,09479066 ! axonal fasciculation GO:0007413 19 7 0,000 0,03472683 0,09468486 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03472683 0,09457931 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03472683 0,09447398 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03472683 0,0943689 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,03472683 0,09426404 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03472683 0,09415942 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03472683 0,09405503 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03472683 0,09395087 ! antibiotic transport GO:0042891 9 7 0,000 0,03472683 0,09384694 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03472683 0,09374325 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03472683 0,09363978 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03472683 0,09353654 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03472683 0,09343352 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03472683 0,09333074 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03472683 0,09322817 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03472683 0,09312584 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03472683 0,09302373 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03472683 0,09292184 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03472683 0,09282017 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03472683 0,09271873 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03472683 0,09261751 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03472683 0,09251651 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03472683 0,09241573 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03472683 0,09231517 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03472683 0,09221482 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03472683 0,0921147 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03472683 0,09201479 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03472683 0,0919151 ! muscle adaptation GO:0043500 13 7 0,000 0,03472683 0,09181563 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03472683 0,09171637 ! retina homeostasis GO:0001895 12 7 0,000 0,03472683 0,09161732 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03472683 0,09151849 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03472683 0,09141987 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03472683 0,09132146 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03472683 0,09122327 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03577714 0,09388137 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,03689079 0,09669978 ! lipid modification GO:0030258 112 60 1,000 0,03689079 0,09659614 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,03801766 0,0994402 ! camera-type eye development GO:0043010 126 61 1,000 0,03801766 0,09933385 ! proton transport GO:0015992 117 61 1,000 0,03801766 0,09922772 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,0391576 0,10209394 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03958891 0,10310843 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,03958891 0,10299863 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03958891 0,10288905 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03958891 0,10277971 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03958891 0,10267061 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03958891 0,10256173 ! male meiosis GO:0007140 9 8 0,000 0,03958891 0,10245308 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03958891 0,10234467 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03958891 0,10223648 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03958891 0,10212852 ! meiotic prophase I GO:0007128 14 8 0,000 0,03958891 0,10202079 ! response to zinc ion GO:0010043 12 8 0,000 0,03958891 0,10191329 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03958891 0,10180601 ! oligopeptide transport GO:0006857 16 8 0,000 0,03958891 0,10169896 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03958891 0,10159213 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03958891 0,10148553 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03958891 0,10137915 ! signal peptide processing GO:0006465 12 8 0,000 0,03958891 0,101273 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03958891 0,10116706 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03958891 0,10106135 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03958891 0,10095586 ! succinate metabolic process GO:0006105 17 8 0,000 0,03958891 0,10085058 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03958891 0,10074553 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03958891 0,1006407 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03958891 0,10053608 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03958891 0,10043168 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03958891 0,1003275 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03958891 0,10022353 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03958891 0,10011978 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03958891 0,10001625 ! reflex GO:0060004 17 8 0,000 0,03958891 0,09991292 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03958891 0,09980981 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03958891 0,09970692 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03958891 0,09960423 ! pigment granule organization GO:0048753 17 8 0,000 0,03958891 0,09950176 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03958891 0,0993995 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03958891 0,09929744 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03958891 0,0991956 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03958891 0,09909397 ! histidine catabolic process GO:0006548 10 8 0,000 0,03958891 0,09899254 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03958891 0,09889132 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03958891 0,09879031 ! ER overload response GO:0006983 13 8 0,000 0,03958891 0,0986895 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03958891 0,0985889 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03958891 0,0984885 ! melanin metabolic process GO:0006582 17 8 0,000 0,03958891 0,09838831 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03958891 0,09828832 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03958891 0,09818854 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03958891 0,09808896 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03958891 0,09798958 ! macrophage activation GO:0042116 13 8 0,000 0,03958891 0,0978904 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03958891 0,09779142 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03958891 0,09769264 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03958891 0,09759406 ! purine salvage GO:0043101 12 8 0,000 0,03958891 0,09749568 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03958891 0,09739749 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03958891 0,09729951 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03958891 0,09720172 ! osteoblast development GO:0002076 17 8 0,000 0,03958891 0,09710413 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03958891 0,09700673 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03958891 0,09690953 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03958891 0,09681252 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03958891 0,09671571 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03958891 0,09661909 ! response to UV-B GO:0010224 17 8 0,000 0,03958891 0,09652267 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03958891 0,09642643 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03958891 0,09633039 ! intermediate filament organization GO:0045109 12 8 0,000 0,03958891 0,09623454 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03958891 0,09613888 ! cellular extravasation GO:0045123 13 8 0,000 0,03958891 0,09604341 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03958891 0,09594813 ! response to antibiotic GO:0046677 11 8 0,000 0,03958891 0,09585303 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03958891 0,09575813 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03958891 0,09566341 ! DNA topological change GO:0006265 12 8 0,000 0,03958891 0,09556888 ! response to tropane GO:0014073 15 8 0,000 0,03958891 0,09547454 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03958891 0,09538039 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03958891 0,09528641 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03958891 0,09519263 ! mast cell activation GO:0045576 14 8 0,000 0,03958891 0,09509903 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03958891 0,09500561 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03958891 0,09491238 ! gas homeostasis GO:0033483 14 8 0,000 0,03958891 0,09481932 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03958891 0,09472646 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03958891 0,09463377 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03958891 0,09454126 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03958891 0,09444894 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03958891 0,09435679 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03958891 0,09426483 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03958891 0,09417304 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03958891 0,09408143 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03958891 0,09399 ! response to tumor cell GO:0002347 16 8 0,000 0,03958891 0,09389875 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03958891 0,09380767 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03958891 0,09371677 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03958891 0,09362605 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03958891 0,0935355 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03958891 0,09344513 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03958891 0,09335493 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03958891 0,09326491 ! hormone catabolic process GO:0042447 17 8 0,000 0,03958891 0,09317506 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03958891 0,09308538 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03958891 0,09299588 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03958891 0,09290654 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03958891 0,09281738 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03958891 0,09272839 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03958891 0,09263957 ! adult feeding behavior GO:0008343 10 8 0,000 0,03958891 0,09255092 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03958891 0,09246244 ! ATP catabolic process GO:0006200 11 8 0,000 0,03958891 0,09237413 ! blastocyst growth GO:0001832 19 8 0,000 0,03958891 0,09228598 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03958891 0,09219801 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03958891 0,0921102 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03958891 0,09202256 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03958891 0,09193509 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03958891 0,09184778 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03958891 0,09176064 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03958891 0,09167366 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03958891 0,09158685 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03958891 0,0915002 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03958891 0,09141372 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03958891 0,09132739 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03958891 0,09124124 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03958891 0,09115524 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03958891 0,09106941 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03958891 0,09098374 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03958891 0,09089822 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03958891 0,09081287 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03958891 0,09072768 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03958891 0,09064265 ! water-soluble vitamin metabolic process GO:0006767 107 63 1,000 0,04031045 0,09220827 ! hydrogen transport GO:0006818 121 64 1,000 0,04147605 0,09478577 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,04147605 0,09469718 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,04265424 0,09729628 GO:0048609|reproductive process in a multicellular organism, ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,04384487 0,09991887 ! gonad development GO:0008406 115 66 1,000 0,04384487 0,09982575 ! axon extension GO:0048675 16 9 0,000 0,04442664 0,10105613 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04442664 0,10096213 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04442664 0,1008683 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04442664 0,10077464 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04442664 0,10068116 GO:0006740|NADPH regeneration, ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04442664 0,10058785 ! reproductive behavior GO:0019098 22 9 0,000 0,04442664 0,10049471 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04442664 0,10040174 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04442664 0,10030895 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04442664 0,10021633 ! UTP metabolic process GO:0046051 10 9 0,000 0,04442664 0,10012388 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04442664 0,1000316 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04442664 0,09993949 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04442664 0,09984755 ! regulation of histone modification GO:0031056 14 9 0,000 0,04442664 0,09975578 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04442664 0,09966417 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04442664 0,09957274 ! equilibrioception GO:0050957 20 9 0,000 0,04442664 0,09948147 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04442664 0,09939037 ! chemosensory behavior GO:0007635 21 9 0,000 0,04442664 0,09929944 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04442664 0,09920867 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04442664 0,09911807 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04442664 0,09902763 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04442664 0,09893736 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04442664 0,09884725 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04442664 0,09875731 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04442664 0,09866753 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04442664 0,09857792 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04442664 0,09848846 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04442664 0,09839917 ! protein targeting to ER GO:0045047 25 9 0,000 0,04442664 0,09831004 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04442664 0,09822107 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04442664 0,09813227 ! T cell selection GO:0045058 27 9 0,000 0,04442664 0,09804362 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,04442664 0,09795513 ! glycine catabolic process GO:0006546 15 9 0,000 0,04442664 0,0978668 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04442664 0,09777864 ! endosome organization GO:0007032 20 9 0,000 0,04442664 0,09769063 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04442664 0,09760278 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04442664 0,09751508 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04442664 0,09742755 ! mannose metabolic process GO:0006013 13 9 0,000 0,04442664 0,09734017 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04442664 0,09725294 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04442664 0,09716588 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04442664 0,09707897 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04442664 0,09699221 ! receptor clustering GO:0043113 20 9 0,000 0,04442664 0,09690561 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04442664 0,09681917 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04442664 0,09673288 ! retinol metabolic process GO:0042572 20 9 0,000 0,04442664 0,09664674 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04442664 0,09656075 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04442664 0,09647492 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04442664 0,09638924 ! macrophage differentiation GO:0030225 15 9 0,000 0,04442664 0,09630371 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04442664 0,09621834 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04442664 0,09613311 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04442664 0,09604804 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04442664 0,09596312 ! response to amine stimulus GO:0014075 13 9 0,000 0,04442664 0,09587834 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04442664 0,09579372 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04442664 0,09570925 ! erythrocyte development GO:0048821 17 9 0,000 0,04442664 0,09562492 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04442664 0,09554074 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04442664 0,09545672 ! renal water homeostasis GO:0003091 15 9 0,000 0,04442664 0,09537283 ! postreplication repair GO:0006301 25 9 0,000 0,04442664 0,0952891 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04442664 0,09520551 ! icosanoid secretion GO:0032309 15 9 0,000 0,04442664 0,09512207 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04442664 0,09503878 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04442664 0,09495563 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04442664 0,09487263 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04442664 0,09478977 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04442664 0,09470706 ! sterol catabolic process GO:0016127 14 9 0,000 0,04442664 0,09462449 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04442664 0,09454206 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04442664 0,09445978 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04442664 0,09437764 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04442664 0,09429564 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04442664 0,09421379 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04442664 0,09413208 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04442664 0,09405051 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04442664 0,09396908 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04442664 0,09388779 ! purine base metabolic process GO:0006144 25 9 0,000 0,04442664 0,09380664 ! pigment granule transport GO:0051904 17 9 0,000 0,04442664 0,09372564 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04442664 0,09364477 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04442664 0,09356404 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04442664 0,09348345 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04442664 0,093403 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04442664 0,09332269 ! mitochondrion localization GO:0051646 18 9 0,000 0,04442664 0,09324251 ! activation of MAPK activity GO:0000187 124 67 1,000 0,04504779 0,09446503 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,04504779 0,09438401 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,04626284 0,09684673 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,04626284 0,09676381 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,04626284 0,09668104 ! lung development GO:0030324 165 69 1,000 0,04748988 0,09916049 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,04748988 0,09907581 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,04748988 0,09899128 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,04748988 0,09890688 ! germ cell development GO:0007281 133 70 1,000 0,04872875 0,10140062 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04924014 0,10237758 ! regulation of developmental growth GO:0048638 16 10 0,000 0,04924014 0,10229053 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04924014 0,10220362 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04924014 0,10211686 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04924014 0,10203025 ! associative learning GO:0008306 21 10 0,000 0,04924014 0,10194378 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04924014 0,10185746 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04924014 0,10177129 ! phosphate transport GO:0006817 24 10 0,000 0,04924014 0,10168526 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04924014 0,10159938 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04924014 0,10151364 ! CTP metabolic process GO:0046036 11 10 0,000 0,04924014 0,10142804 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04924014 0,10134259 ! GTP metabolic process GO:0046039 11 10 0,000 0,04924014 0,10125729 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04924014 0,10117213 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04924014 0,10108711 ! social behavior GO:0035176 29 10 0,000 0,04924014 0,10100223 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04924014 0,1009175 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04924014 0,10083291 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04924014 0,10074846 ! androgen metabolic process GO:0008209 17 10 0,000 0,04924014 0,10066415 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04924014 0,10057998 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04924014 0,10049596 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04924014 0,10041207 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04924014 0,10032832 ! lung alveolus development GO:0048286 26 10 0,000 0,04924014 0,10024472 ! pathogenesis GO:0009405 17 10 0,000 0,04924014 0,10016125 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04924014 0,10007792 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04924014 0,09999473 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04924014 0,09991168 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04924014 0,09982876 ! endoderm development GO:0007492 18 10 0,000 0,04924014 0,09974599 ! arginine catabolic process GO:0006527 17 10 0,000 0,04924014 0,09966335 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04924014 0,09958084 ! proline metabolic process GO:0006560 13 10 0,000 0,04924014 0,09949848 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04924014 0,09941625 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04924014 0,09933415 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04924014 0,09925219 ! V(D)J recombination GO:0033151 34 10 0,000 0,04924014 0,09917037 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04924014 0,09908868 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04924014 0,09900713 ! B cell proliferation GO:0042100 19 10 0,000 0,04924014 0,09892571 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04924014 0,09884442 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04924014 0,09876327 ! multicellular organism growth GO:0035264 19 10 0,000 0,04924014 0,09868225 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04924014 0,09860136 ! ruffle organization GO:0031529 17 10 0,000 0,04924014 0,09852061 ! epithelial cell development GO:0002064 21 10 0,000 0,04924014 0,09843998 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04924014 0,09835949 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04924014 0,09827913 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04924014 0,09819891 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04924014 0,09811881 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04924014 0,09803884 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04924014 0,09795901 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04924014 0,0978793 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04924014 0,09779972 ! protein heterooligomerization GO:0051291 17 10 0,000 0,04924014 0,09772028 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04924014 0,09764096 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04924014 0,09756177 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04924014 0,09748271 ! segment specification GO:0007379 15 10 0,000 0,04924014 0,09740377 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04924014 0,09732497 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04924014 0,09724629 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04924014 0,09716774 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04924014 0,09708931 ! response to dsRNA GO:0043331 23 10 0,000 0,04924014 0,09701102 ! DNA ligation GO:0006266 18 10 0,000 0,04924014 0,09693284 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04924014 0,0968548 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04924014 0,09677688 ! melanosome localization GO:0032400 16 10 0,000 0,04924014 0,09669908 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04924014 0,09662141 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04924014 0,09654387 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04924014 0,09646645 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04924014 0,09638915 ! induction of an organ GO:0001759 17 10 0,000 0,04924014 0,09631198 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04924014 0,09623493 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04924014 0,096158 ! protein sumoylation GO:0016925 17 10 0,000 0,04924014 0,0960812 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04924014 0,09600452 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04924014 0,09592796 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04924014 0,09585152 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04924014 0,09577521 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04924014 0,09569901 ! salivary gland development GO:0007431 28 10 0,000 0,04924014 0,09562294 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04924014 0,09554699 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04924014 0,09547116 ! midbrain development GO:0030901 14 10 0,000 0,04924014 0,09539545 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04924014 0,09531986 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04924014 0,09524439 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04924014 0,09516903 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04924014 0,0950938 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04924014 0,09501869 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04924014 0,09494369 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04924014 0,09486882 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04924014 0,09479406 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,04924014 0,09471942 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,04924014 0,09464489 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04924014 0,09457049 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04924014 0,0944962 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04924014 0,09442203 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04924014 0,09434797 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04924014 0,09427403 ! response to nicotine GO:0035094 20 10 0,000 0,04924014 0,0942002 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04924014 0,09412649 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04924014 0,0940529 ! carbohydrate transport GO:0008643 114 72 1,000 0,05124138 0,09779898 ! respiratory tube development GO:0030323 171 72 1,000 0,05124138 0,09772264 ! actin filament organization GO:0007015 167 72 1,000 0,05124138 0,09764641 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,05124138 0,0975703 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,05124138 0,09749431 ! amino acid transport GO:0006865 148 74 1,000 0,05379958 0,102282 ! respiratory system development GO:0060541 175 74 1,000 0,05379958 0,10220247 ! organelle localization GO:0051640 155 74 1,000 0,05379958 0,10212306 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05402952 0,10247991 ! respiratory burst GO:0045730 17 11 0,000 0,05402952 0,10240041 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05402952 0,10232103 ! neuron fate specification GO:0048665 18 11 0,000 0,05402952 0,10224177 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05402952 0,10216264 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05402952 0,10208363 ! thyroid gland development GO:0030878 26 11 0,000 0,05402952 0,10200474 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,05402952 0,10192597 ! synapsis GO:0007129 14 11 0,000 0,05402952 0,10184732 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05402952 0,1017688 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05402952 0,10169039 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05402952 0,10161211 ! response to pain GO:0048265 27 11 0,000 0,05402952 0,10153394 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05402952 0,1014559 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05402952 0,10137798 ! bone resorption GO:0045453 16 11 0,000 0,05402952 0,10130018 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05402952 0,10122249 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,05402952 0,10114493 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05402952 0,10106748 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05402952 0,10099015 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05402952 0,10091294 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05402952 0,10083585 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05402952 0,10075888 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05402952 0,10068202 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05402952 0,10060528 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05402952 0,10052866 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05402952 0,10045215 ! UV protection GO:0009650 20 11 0,000 0,05402952 0,10037576 ! adult heart development GO:0007512 16 11 0,000 0,05402952 0,10029949 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05402952 0,10022333 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05402952 0,10014729 ! macroautophagy GO:0016236 19 11 0,000 0,05402952 0,10007136 ! temperature homeostasis GO:0001659 18 11 0,000 0,05402952 0,09999555 ! behavioral fear response GO:0001662 27 11 0,000 0,05402952 0,09991985 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05402952 0,09984427 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05402952 0,0997688 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05402952 0,09969345 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05402952 0,09961821 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05402952 0,09954308 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05402952 0,09946807 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05402952 0,09939317 ! regulation of organ growth GO:0046620 14 11 0,000 0,05402952 0,09931838 ! pigment granule localization GO:0051875 20 11 0,000 0,05402952 0,09924371 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05402952 0,09916914 ! vasoconstriction GO:0042310 20 11 0,000 0,05402952 0,09909469 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05402952 0,09902035 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05402952 0,09894612 ! embryonic axis specification GO:0000578 19 11 0,000 0,05402952 0,09887201 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05402952 0,098798 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05402952 0,0987241 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05402952 0,09865032 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05402952 0,09857665 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05402952 0,09850308 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05402952 0,09842963 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05402952 0,09835628 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05402952 0,09828304 ! prophase GO:0051324 17 11 0,000 0,05402952 0,09820992 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05402952 0,0981369 ! nucleosome positioning GO:0016584 15 11 0,000 0,05402952 0,09806399 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05402952 0,09799119 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05402952 0,09791849 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05402952 0,09784591 ! apical protein localization GO:0045176 18 11 0,000 0,05402952 0,09777343 ! acid secretion GO:0046717 20 11 0,000 0,05402952 0,09770106 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05402952 0,09762879 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05402952 0,09755664 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05402952 0,09748459 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05402952 0,09741264 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05402952 0,0973408 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05402952 0,09726907 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05402952 0,09719744 ! oocyte development GO:0048599 20 11 0,000 0,05402952 0,09712592 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05402952 0,09705451 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 19 11 0,000 0,05402952 0,09698319 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05402952 0,09691199 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05402952 0,09684089 ! activation of innate immune response GO:0002218 16 11 0,000 0,05402952 0,09676989 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05402952 0,096699 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05402952 0,09662821 ! lysogeny GO:0030069 22 11 0,000 0,05402952 0,09655752 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05402952 0,09648694 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05402952 0,09641646 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05402952 0,09634608 ! nucleus localization GO:0051647 22 11 0,000 0,05402952 0,0962758 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,0550954 0,09810354 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 155 75 1,000 0,0550954 0,09803209 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,05640218 0,10028422 ! learning or memory GO:0007611 161 76 1,000 0,05640218 0,10021129 ! amine catabolic process GO:0009310 136 77 1,000 0,05771977 0,10247776 ! neurotransmitter transport GO:0006836 142 77 1,000 0,05771977 0,10240334 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,05771977 0,10232903 ! regulation of catabolic process GO:0009894 173 77 1,000 0,05771977 0,10225482 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05879492 0,10408405 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05879492 0,10400868 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,05879492 0,10393342 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05879492 0,10385827 ! virus-host interaction GO:0019048 30 12 0,000 0,05879492 0,10378323 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05879492 0,10370829 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05879492 0,10363347 ! protein complex disassembly GO:0043241 28 12 0,000 0,05879492 0,10355875 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05879492 0,10348414 ! hippocampus development GO:0021766 29 12 0,000 0,05879492 0,10340964 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05879492 0,10333524 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05879492 0,10326095 ! T cell proliferation GO:0042098 32 12 0,000 0,05879492 0,10318677 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05879492 0,10311269 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05879492 0,10303873 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05879492 0,10296486 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05879492 0,10289111 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05879492 0,10281745 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05879492 0,10274391 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05879492 0,10267047 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05879492 0,10259713 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05879492 0,1025239 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05879492 0,10245077 ! lipid digestion GO:0044241 21 12 0,000 0,05879492 0,10237775 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05879492 0,10230483 ! entry into host cell GO:0030260 34 12 0,000 0,05879492 0,10223202 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05879492 0,10215931 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05879492 0,1020867 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05879492 0,10201419 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05879492 0,10194179 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05879492 0,10186949 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05879492 0,1017973 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05879492 0,1017252 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05879492 0,10165321 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05879492 0,10158132 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05879492 0,10150953 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05879492 0,10143784 ! cranial nerve development GO:0021545 23 12 0,000 0,05879492 0,10136626 ! fucose catabolic process GO:0019317 25 12 0,000 0,05879492 0,10129477 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05879492 0,10122339 ! histone acetylation GO:0016573 27 12 0,000 0,05879492 0,1011521 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05879492 0,10108092 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05879492 0,10100983 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05879492 0,10093885 ! zymogen activation GO:0031638 18 12 0,000 0,05879492 0,10086797 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05879492 0,10079718 ! T cell homeostasis GO:0043029 28 12 0,000 0,05879492 0,1007265 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05879492 0,10065591 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05879492 0,10058542 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,05879492 0,10051503 ! oocyte differentiation GO:0009994 21 12 0,000 0,05879492 0,10044474 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05879492 0,10037455 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05879492 0,10030446 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,05879492 0,10023446 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05879492 0,10016456 ! defense response to fungus GO:0050832 15 12 0,000 0,05879492 0,10009476 ! developmental induction GO:0031128 22 12 0,000 0,05879492 0,10002506 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,05879492 0,09995545 ! response to cold GO:0009409 17 12 0,000 0,05879492 0,09988594 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05879492 0,09981653 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05879492 0,09974721 ! localization within membrane GO:0051668 26 12 0,000 0,05879492 0,09967799 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,05904804 0,1000377 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,06173604 0,10451916 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,06173604 0,10444678 ! meiosis GO:0007126 143 81 1,000 0,0630955 0,10667288 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,0630955 0,10659911 ! response to hypoxia GO:0001666 178 81 1,000 0,0630955 0,10652544 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06353644 0,1071958 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06353644 0,10712182 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06353644 0,10704794 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06353644 0,10697417 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06353644 0,10690049 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06353644 0,10682692 ! peroxisomal transport GO:0043574 28 13 0,000 0,06353644 0,10675345 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06353644 0,10668008 ! cartilage condensation GO:0001502 22 13 0,000 0,06353644 0,10660681 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06353644 0,10653364 ! organelle fusion GO:0048284 36 13 0,000 0,06353644 0,10646058 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06353644 0,10638761 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06353644 0,10631474 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06353644 0,10624197 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06353644 0,1061693 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06353644 0,10609673 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06353644 0,10602426 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06353644 0,10595189 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06353644 0,10587962 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06353644 0,10580744 ! methionine metabolic process GO:0006555 31 13 0,000 0,06353644 0,10573537 ! plasma membrane organization GO:0007009 27 13 0,000 0,06353644 0,10566339 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06353644 0,10559151 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06353644 0,10551973 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06353644 0,10544804 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06353644 0,10537646 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06353644 0,10530497 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06353644 0,10523357 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06353644 0,10516228 ! exocrine system development GO:0035272 34 13 0,000 0,06353644 0,10509108 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06353644 0,10501997 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06353644 0,10494896 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06353644 0,10487805 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06353644 0,10480724 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06353644 0,10473652 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06353644 0,10466589 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06353644 0,10459536 ! protein homotetramerization GO:0051289 24 13 0,000 0,06353644 0,10452493 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06353644 0,10445459 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06353644 0,10438434 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06353644 0,10431419 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06353644 0,10424414 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06353644 0,10417417 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06353644 0,1041043 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06353644 0,10403453 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06353644 0,10396485 ! histone methylation GO:0016571 29 13 0,000 0,06353644 0,10389526 ! chromatin silencing GO:0006342 29 13 0,000 0,06353644 0,10382576 ! gland morphogenesis GO:0022612 31 13 0,000 0,06353644 0,10375636 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06353644 0,10368705 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06353644 0,10361784 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06353644 0,10354871 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06353644 0,10347968 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06353644 0,10341074 ! spleen development GO:0048536 24 13 0,000 0,06353644 0,10334189 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06353644 0,10327313 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06353644 0,10320447 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06353644 0,10313589 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06353644 0,10306741 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06353644 0,10299902 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06353644 0,10293072 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06353644 0,1028625 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06353644 0,10279438 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06353644 0,10272635 ! insulin secretion GO:0030073 24 13 0,000 0,06353644 0,10265841 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06353644 0,10259056 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06353644 0,1025228 ! acrosome reaction GO:0007340 19 13 0,000 0,06353644 0,10245513 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06353644 0,10238755 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06353644 0,10232005 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,06446508 0,10374716 ! protein import into nucleus GO:0006606 174 82 1,000 0,06446508 0,10367886 ! meiotic cell cycle GO:0051321 144 82 1,000 0,06446508 0,10361066 ! response to oxygen levels GO:0070482 183 83 1,000 0,06584465 0,10575837 ! nuclear import GO:0051170 177 83 1,000 0,06584465 0,10568889 ! response to metal ion GO:0010038 158 84 1,000 0,06723408 0,10784823 ! rRNA transcription GO:0009303 28 14 0,000 0,06825421 0,10941274 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06825421 0,109341 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06825421 0,10926935 ! water transport GO:0006833 21 14 0,000 0,06825421 0,10919779 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06825421 0,10912632 ! non-recombinational repair GO:0000726 29 14 0,000 0,06825421 0,10905495 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06825421 0,10898368 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06825421 0,10891249 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06825421 0,1088414 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06825421 0,1087704 ! lipid localization GO:0010876 32 14 0,000 0,06825421 0,10869949 GO:0019915|lipid storage, ! regulated secretory pathway GO:0045055 24 14 0,000 0,06825421 0,10862868 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06825421 0,10855796 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06825421 0,10848733 ! arginine metabolic process GO:0006525 21 14 0,000 0,06825421 0,10841679 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06825421 0,10834634 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06825421 0,10827599 ! regulation of heart rate GO:0002027 25 14 0,000 0,06825421 0,10820573 ! fear response GO:0042596 34 14 0,000 0,06825421 0,10813555 ! organic alcohol transport GO:0015850 29 14 0,000 0,06825421 0,10806547 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06825421 0,10799548 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06825421 0,10792558 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06825421 0,10785577 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06825421 0,10778605 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06825421 0,10771642 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06825421 0,10764688 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06825421 0,10757743 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06825421 0,10750807 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06825421 0,1074388 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06825421 0,10736962 ! ribosome assembly GO:0042255 18 14 0,000 0,06825421 0,10730053 ! cerebellum development GO:0021549 23 14 0,000 0,06825421 0,10723153 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06825421 0,10716261 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06825421 0,10709378 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06825421 0,10702505 ! response to gamma radiation GO:0010332 30 14 0,000 0,06825421 0,1069564 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06825421 0,10688784 ! NADP metabolic process GO:0006739 24 14 0,000 0,06825421 0,10681936 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06825421 0,10675098 ! oxygen transport GO:0015671 22 14 0,000 0,06825421 0,10668268 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06825421 0,10661446 ! regulation of RNA stability GO:0043487 33 14 0,000 0,06825421 0,10654634 ! regulation of axon extension GO:0030516 43 14 0,000 0,06825421 0,1064783 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06825421 0,10641035 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06825421 0,10634249 ! negative regulation of transport GO:0051051 164 85 1,000 0,06863322 0,10686486 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,06863322 0,10679679 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,06863322 0,10672881 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,06863322 0,10666092 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,07004196 0,10878099 ! regulation of protein transport GO:0051223 165 87 1,000 0,07146015 0,11091305 GO:0070201|regulation of establishment of protein localization, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07294834 0,11315098 ! lactation GO:0007595 30 15 0,000 0,07294834 0,11307918 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07294834 0,11300747 ! reproductive cellular process GO:0048610 22 15 0,000 0,07294834 0,11293586 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07294834 0,11286434 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07294834 0,1127929 ! superoxide anion generation GO:0042554 22 15 0,000 0,07294834 0,11272156 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07294834 0,11265031 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07294834 0,11257915 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07294834 0,11250807 ! copper ion transport GO:0006825 22 15 0,000 0,07294834 0,11243709 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07294834 0,1123662 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07294834 0,11229539 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07294834 0,11222468 ! sulfate transport GO:0008272 27 15 0,000 0,07294834 0,11215405 ! response to cAMP GO:0051591 25 15 0,000 0,07294834 0,11208351 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07294834 0,11201307 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07294834 0,11194271 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07294834 0,11187243 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07294834 0,11180225 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07294834 0,11173215 ! vesicle coating GO:0006901 38 15 0,000 0,07294834 0,11166215 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07294834 0,11159223 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07294834 0,11152239 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07294834 0,11145265 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07294834 0,11138299 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07294834 0,11131342 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07294834 0,11124394 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07294834 0,11117454 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07294834 0,11110523 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07294834 0,111036 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07294834 0,11096687 ! histone deacetylation GO:0016575 24 15 0,000 0,07294834 0,11089781 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07294834 0,11082885 ! water homeostasis GO:0030104 28 15 0,000 0,07294834 0,11075997 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07294834 0,11069117 ! muscle maintenance GO:0046716 26 15 0,000 0,07294834 0,11062246 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07294834 0,11055384 ! intestinal absorption GO:0050892 31 15 0,000 0,07294834 0,1104853 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07294834 0,11041684 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07294834 0,11034847 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07294834 0,11028019 ! cell killing GO:0001906 32 15 0,000 0,07294834 0,11021199 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07294834 0,11014387 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07294834 0,11007584 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07294834 0,11000789 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07294834 0,10994003 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07294834 0,10987225 ! actin filament polymerization GO:0030041 27 15 0,000 0,07294834 0,10980455 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07294834 0,10973694 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,07432439 0,11173815 ! regulation of DNA binding GO:0051101 167 89 1,000 0,07432439 0,11166943 ! response to inorganic substance GO:0010035 173 90 1,000 0,07577019 0,11377171 ! oxidative phosphorylation GO:0006119 152 90 1,000 0,07577019 0,11370183 ! response to unfolded protein GO:0006986 139 90 1,000 0,07577019 0,11363203 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,07722493 0,11574264 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,07722493 0,11567168 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07761895 0,11619062 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07761895 0,11611947 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07761895 0,11604841 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07761895 0,11597743 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07761895 0,11590654 ! bone remodeling GO:0046849 28 16 0,000 0,07761895 0,11583573 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07761895 0,11576502 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07761895 0,11569439 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07761895 0,11562384 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07761895 0,11555338 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07761895 0,11548301 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07761895 0,11541272 ! startle response GO:0001964 28 16 0,000 0,07761895 0,11534252 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07761895 0,1152724 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07761895 0,11520237 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07761895 0,11513242 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07761895 0,11506256 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07761895 0,11499278 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07761895 0,11492309 ! pituitary gland development GO:0021983 30 16 0,000 0,07761895 0,11485348 ! response to osmotic stress GO:0006970 27 16 0,000 0,07761895 0,11478396 ! lysosomal transport GO:0007041 31 16 0,000 0,07761895 0,11471452 ! fructose metabolic process GO:0006000 25 16 0,000 0,07761895 0,11464516 ! L-amino acid transport GO:0015807 33 16 0,000 0,07761895 0,11457589 ! stem cell development GO:0048864 46 16 0,000 0,07761895 0,1145067 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07761895 0,1144376 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07761895 0,11436857 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07761895 0,11429964 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07761895 0,11423078 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07761895 0,11416201 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07761895 0,11409332 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,07761895 0,11402471 ! DNA replication initiation GO:0006270 28 16 0,000 0,07761895 0,11395619 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07761895 0,11388775 ! tissue regeneration GO:0042246 27 16 0,000 0,07761895 0,11381939 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07761895 0,11375111 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07761895 0,11368291 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,07761895 0,1136148 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07761895 0,11354676 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07761895 0,11347881 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07761895 0,11341094 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07761895 0,11334315 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07761895 0,11327545 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07761895 0,11320782 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07761895 0,11314027 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07761895 0,11307281 ! peptide hormone processing GO:0016486 27 16 0,000 0,07761895 0,11300542 ! bone development GO:0060348 206 92 1,000 0,07868849 0,11449433 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,08016075 0,11656708 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,08016075 0,11649774 ! vitamin metabolic process GO:0006766 153 93 1,000 0,08016075 0,11642848 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,08164157 0,11850883 ! female pregnancy GO:0007565 166 94 1,000 0,08164157 0,11843846 ! sterol metabolic process GO:0016125 166 94 1,000 0,08164157 0,11836817 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,08164157 0,11829796 ! regulation of membrane potential GO:0042391 179 94 1,000 0,08164157 0,11822784 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08226616 0,11906175 ! metencephalon development GO:0022037 32 17 0,000 0,08226616 0,11899126 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08226616 0,11892085 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08226616 0,11885053 ! signal complex assembly GO:0007172 47 17 0,000 0,08226616 0,11878028 ! filopodium assembly GO:0046847 42 17 0,000 0,08226616 0,11871012 ! endothelial cell migration GO:0043542 31 17 0,000 0,08226616 0,11864005 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08226616 0,11857005 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08226616 0,11850014 ! glial cell development GO:0021782 28 17 0,000 0,08226616 0,11843031 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08226616 0,11836057 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08226616 0,1182909 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08226616 0,11822132 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08226616 0,11815182 ! myoblast differentiation GO:0045445 50 17 0,000 0,08226616 0,1180824 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08226616 0,11801306 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08226616 0,1179438 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08226616 0,11787463 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08226616 0,11780553 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08226616 0,11773652 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08226616 0,11766759 ! membrane budding GO:0006900 42 17 0,000 0,08226616 0,11759874 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08226616 0,11752996 ! regulation of protein binding GO:0043393 33 17 0,000 0,08226616 0,11746127 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08226616 0,11739266 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08226616 0,11732413 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08226616 0,11725568 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08226616 0,11718731 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08226616 0,11711902 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,08226616 0,11705081 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08226616 0,11698268 ! steroid catabolic process GO:0006706 34 17 0,000 0,08226616 0,11691462 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08226616 0,11684665 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08226616 0,11677876 ! gas transport GO:0015669 26 17 0,000 0,08226616 0,11671094 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08226616 0,1166432 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08226616 0,11657555 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08226616 0,11650797 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,08313085 0,11766435 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,08313085 0,11759622 ! response to protein stimulus GO:0051789 158 96 1,000 0,08462846 0,11964544 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,08613427 0,12170389 ! transcription initiation GO:0006352 171 97 1,000 0,08613427 0,12163354 ! regulation of protein localization GO:0032880 188 97 1,000 0,08613427 0,12156327 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08689009 0,12255918 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08689009 0,12248846 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08689009 0,12241782 ! limbic system development GO:0021761 40 18 0,000 0,08689009 0,12234726 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08689009 0,12227679 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08689009 0,12220639 ! adult walking behavior GO:0007628 36 18 0,000 0,08689009 0,12213608 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08689009 0,12206584 ! heart looping GO:0001947 34 18 0,000 0,08689009 0,12199569 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08689009 0,12192562 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08689009 0,12185563 ! centrosome cycle GO:0007098 26 18 0,000 0,08689009 0,12178571 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08689009 0,12171588 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08689009 0,12164613 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08689009 0,12157646 ! glycine metabolic process GO:0006544 30 18 0,000 0,08689009 0,12150687 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08689009 0,12143736 ! response to retinoic acid GO:0032526 31 18 0,000 0,08689009 0,12136792 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,08689009 0,12129857 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08689009 0,1212293 ! DNA integration GO:0015074 32 18 0,000 0,08689009 0,1211601 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,08689009 0,12109099 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08689009 0,12102195 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08689009 0,12095299 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08689009 0,12088411 ! neural crest cell migration GO:0001755 41 18 0,000 0,08689009 0,12081531 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08689009 0,12074659 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08689009 0,12067794 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08689009 0,12060938 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08689009 0,12054089 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,08689009 0,12047247 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,08689009 0,12040414 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,08689009 0,12033588 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08689009 0,12026771 ! detection of bacterium GO:0016045 22 18 0,000 0,08689009 0,1201996 ! nerve development GO:0021675 34 18 0,000 0,08689009 0,12013158 ! defense response to virus GO:0051607 43 18 0,000 0,08689009 0,12006363 ! microspike assembly GO:0030035 46 18 0,000 0,08689009 0,11999576 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08689009 0,11992797 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,08689009 0,11986025 ! forebrain development GO:0030900 210 98 1,000 0,08764817 0,12083775 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,08764817 0,12076959 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,09069977 0,12490391 GO:0060538|skeletal muscle organ development, ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09149086 0,12592235 ! positive regulation of translation GO:0045727 31 19 0,000 0,09149086 0,12585144 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09149086 0,12578062 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09149086 0,12570988 ! neuron maturation GO:0042551 46 19 0,000 0,09149086 0,12563921 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09149086 0,12556863 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09149086 0,12549813 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09149086 0,1254277 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09149086 0,12535735 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09149086 0,12528709 ! inositol metabolic process GO:0006020 33 19 0,000 0,09149086 0,1252169 ! memory GO:0007613 34 19 0,000 0,09149086 0,12514679 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09149086 0,12507676 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09149086 0,1250068 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09149086 0,12493693 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09149086 0,12486713 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09149086 0,12479741 ! cerebral cortex development GO:0021987 40 19 0,000 0,09149086 0,12472777 ! response to vitamin A GO:0033189 32 19 0,000 0,09149086 0,12465821 ! heme metabolic process GO:0042168 40 19 0,000 0,09149086 0,12458872 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09149086 0,12451931 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09149086 0,12444998 ! response to fungus GO:0009620 26 19 0,000 0,09149086 0,12438072 ! peptide cross-linking GO:0018149 39 19 0,000 0,09149086 0,12431155 ! protein export from nucleus GO:0006611 40 19 0,000 0,09149086 0,12424245 ! heart process GO:0003015 32 19 0,000 0,09149086 0,12417342 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09149086 0,12410448 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09149086 0,12403561 ! visual learning GO:0008542 38 19 0,000 0,09149086 0,12396681 ! cellular pigmentation GO:0033059 37 19 0,000 0,09149086 0,12389809 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09149086 0,12382945 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09149086 0,12376089 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09149086 0,1236924 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09149086 0,12362398 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09149086 0,12355565 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09149086 0,12348738 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09149086 0,1234192 ! cilium assembly GO:0042384 38 19 0,000 0,09149086 0,12335108 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09149086 0,12328305 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09606857 0,1293801 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09606857 0,12930882 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09606857 0,12923761 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09606857 0,12916649 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,09606857 0,12909544 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09606857 0,12902447 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09606857 0,12895358 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,09606857 0,12888276 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,09606857 0,12881202 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09606857 0,12874136 ! response to vitamin GO:0033273 36 20 0,000 0,09606857 0,12867078 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09606857 0,12860028 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,09606857 0,12852985 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09606857 0,1284595 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09606857 0,12838923 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09606857 0,12831903 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,09606857 0,12824891 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09606857 0,12817887 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09606857 0,1281089 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,09606857 0,12803901 GO:0030968|endoplasmic reticulum unfolded protein response, ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09606857 0,1279692 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09606857 0,12789946 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09606857 0,1278298 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09606857 0,12776021 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09606857 0,1276907 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09606857 0,12762127 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09606857 0,12755191 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09606857 0,12748262 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09606857 0,12741341 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09606857 0,12734428 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09606857 0,12727522 ! regulation of glucose import GO:0046324 30 20 0,000 0,09606857 0,12720624 GO:0010827|regulation of glucose transport, ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09606857 0,12713733 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09606857 0,12706849 ! regulation of cell killing GO:0031341 46 21 0,000 0,10062334 0,133021 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10062334 0,13294906 ! hormone secretion GO:0046879 39 21 0,000 0,10062334 0,1328772 ! lipid phosphorylation GO:0046834 43 21 0,000 0,10062334 0,13280541 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10062334 0,1327337 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10062334 0,13266207 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10062334 0,13259052 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10062334 0,13251904 ! ovarian follicle development GO:0001541 39 21 0,000 0,10062334 0,13244764 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10062334 0,13237631 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,10062334 0,13230507 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10062334 0,1322339 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10062334 0,1321628 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10062334 0,13209179 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10062334 0,13202085 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10062334 0,13194998 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10062334 0,13187919 ! sensory perception of pain GO:0019233 33 21 0,000 0,10062334 0,13180848 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10062334 0,13173784 ! diencephalon development GO:0021536 36 21 0,000 0,10062334 0,13166728 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10062334 0,1315968 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10062334 0,13152639 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10062334 0,13145605 ! collagen catabolic process GO:0030574 29 21 0,000 0,10062334 0,13138579 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10062334 0,13131561 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10062334 0,1312455 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10062334 0,13117546 ! actin filament-based movement GO:0030048 47 21 0,000 0,10062334 0,1311055 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10062334 0,13103562 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10515529 0,13686434 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10515529 0,13679146 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10515529 0,13671866 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10515529 0,13664594 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10515529 0,13657329 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,10515529 0,13650073 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,10515529 0,13642824 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,10515529 0,13635582 ! cellular response to starvation GO:0009267 37 22 0,000 0,10515529 0,13628348 ! vacuolar transport GO:0007034 41 22 0,000 0,10515529 0,13621122 ! fucose metabolic process GO:0006004 44 22 0,000 0,10515529 0,13613904 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,10515529 0,13606693 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10515529 0,1359949 ! ureteric bud development GO:0001657 50 22 0,000 0,10515529 0,13592295 ! cell aging GO:0007569 48 22 0,000 0,10515529 0,13585107 ! stem cell differentiation GO:0048863 57 22 0,000 0,10515529 0,13577926 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10515529 0,13570754 ! cytolysis GO:0019835 27 22 0,000 0,10515529 0,13563589 ! renal system process GO:0003014 42 22 0,000 0,10515529 0,13556431 ! vasodilation GO:0042311 40 22 0,000 0,10515529 0,13549281 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10515529 0,13542138 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,10515529 0,13535004 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10515529 0,13527876 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10515529 0,13520756 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,10515529 0,13513644 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10515529 0,13506539 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10515529 0,13499441 ! sarcomere organization GO:0045214 32 22 0,000 0,10515529 0,13492351 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,10515529 0,13485269 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10515529 0,13478193 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10515529 0,13471126 ! gut development GO:0048565 44 22 0,000 0,10515529 0,13464065 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10515529 0,13457012 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10515529 0,13449967 ! protein stabilization GO:0050821 41 22 0,000 0,10515529 0,13442929 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10966453 0,14012052 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10966453 0,14004728 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10966453 0,13997411 ! viral genome replication GO:0019079 44 23 0,000 0,10966453 0,13990101 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10966453 0,139828 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10966453 0,13975505 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,10966453 0,13968219 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10966453 0,1396094 ! regeneration GO:0031099 42 23 0,000 0,10966453 0,13953669 ! axis specification GO:0009798 43 23 0,000 0,10966453 0,13946405 ! visual behavior GO:0007632 46 23 0,000 0,10966453 0,13939149 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10966453 0,139319 ! response to ethanol GO:0045471 47 23 0,000 0,10966453 0,13924659 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10966453 0,13917425 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10966453 0,13910199 ! peroxisome organization GO:0007031 43 23 0,000 0,10966453 0,13902981 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10966453 0,1389577 ! vesicle targeting GO:0006903 49 23 0,000 0,10966453 0,13888566 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,10966453 0,1388137 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10966453 0,13874181 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10966453 0,13867 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10966453 0,13859826 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10966453 0,1385266 ! DNA modification GO:0006304 36 23 0,000 0,10966453 0,13845501 ! fatty acid transport GO:0015908 47 23 0,000 0,10966453 0,13838349 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10966453 0,13831205 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,10966453 0,13824068 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10966453 0,13816939 ! hormone transport GO:0009914 41 23 0,000 0,10966453 0,13809816 ! cell-cell recognition GO:0009988 28 23 0,000 0,10966453 0,13802702 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10966453 0,13795594 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10966453 0,13788494 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10966453 0,13781401 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11415117 0,14337856 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11415117 0,14330489 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,11415117 0,14323128 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11415117 0,14315776 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11415117 0,1430843 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11415117 0,14301093 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11415117 0,14293763 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11415117 0,1428644 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11415117 0,14279125 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11415117 0,14271817 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11415117 0,14264517 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11415117 0,14257224 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11415117 0,14249939 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11415117 0,14242661 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11415117 0,14235391 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11415117 0,14228128 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11415117 0,14220872 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11415117 0,14213624 ! membrane depolarization GO:0051899 45 24 0,000 0,11415117 0,14206383 ! pallium development GO:0021543 56 24 0,000 0,11415117 0,1419915 ! oogenesis GO:0048477 44 24 0,000 0,11415117 0,14191924 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11415117 0,14184705 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11415117 0,14177494 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,11415117 0,1417029 ! platelet activation GO:0030168 41 24 0,000 0,11415117 0,14163093 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11415117 0,14155904 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11415117 0,14148722 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11415117 0,14141547 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11415117 0,1413438 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,11415117 0,14127219 ! regulation of amine transport GO:0051952 41 24 0,000 0,11415117 0,14120066 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,11415117 0,1411292 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,11861533 0,14657423 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,11861533 0,14650013 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,11861533 0,1464261 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,11861533 0,14635215 ! leukocyte adhesion GO:0007159 55 25 0,000 0,11861533 0,14627827 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,11861533 0,14620446 ! phototransduction GO:0007602 37 25 0,000 0,11861533 0,14613074 ! keratinization GO:0031424 37 25 0,000 0,11861533 0,14605708 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,11861533 0,1459835 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,11861533 0,14590999 ! receptor metabolic process GO:0043112 53 25 0,000 0,11861533 0,14583656 ! chromosome condensation GO:0030261 48 25 0,000 0,11861533 0,1457632 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,11861533 0,14568992 ! regulation of behavior GO:0050795 48 25 0,000 0,11861533 0,14561671 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,11861533 0,14554357 ! interaction with host GO:0051701 66 25 0,000 0,11861533 0,14547051 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,11861533 0,14539752 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,11861533 0,1453246 ! immunoglobulin production GO:0002377 62 25 0,000 0,11861533 0,14525175 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,11861533 0,14517898 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,11861533 0,14510628 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,11861533 0,14503366 ! liver development GO:0001889 55 25 0,000 0,11861533 0,14496111 ! protein tetramerization GO:0051262 57 25 0,000 0,11861533 0,14488862 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12305712 0,15023915 ! initiation of viral infection GO:0019059 60 26 0,000 0,12305712 0,1501641 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12305712 0,15008913 ! molting cycle process GO:0022404 52 26 0,000 0,12305712 0,15001424 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12305712 0,14993942 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12305712 0,14986467 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12305712 0,14979 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12305712 0,14971541 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12305712 0,14964088 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12305712 0,14956644 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12305712 0,14949206 ! digestive system process GO:0022600 49 26 0,000 0,12305712 0,14941776 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12305712 0,14934354 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12305712 0,14926938 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12305712 0,1491953 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,12305712 0,1491213 ! neural crest cell development GO:0014032 59 26 0,000 0,12305712 0,14904737 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12305712 0,14897351 ! negative regulation of cell development GO:0010721 83 26 0,000 0,12305712 0,14889972 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12305712 0,14882601 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12305712 0,14875237 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12305712 0,1486788 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12305712 0,14860531 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12305712 0,14853189 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12305712 0,14845854 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,12305712 0,14838526 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12305712 0,14831206 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12305712 0,14823892 ! neural tube closure GO:0001843 58 26 0,000 0,12305712 0,14816586 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,12305712 0,14809288 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12305712 0,14801996 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,12747664 0,15326055 ! embryonic pattern specification GO:0009880 49 27 0,000 0,12747664 0,15318517 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,12747664 0,15310985 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,12747664 0,15303462 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,12747664 0,15295945 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,12747664 0,15288436 ! iron ion transport GO:0006826 65 27 0,000 0,12747664 0,15280934 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,12747664 0,1527344 ! superoxide metabolic process GO:0006801 41 27 0,000 0,12747664 0,15265953 ! tube lumen formation GO:0035148 59 27 0,000 0,12747664 0,15258473 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,12747664 0,15251001 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,12747664 0,15243536 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,12747664 0,15236078 ! response to starvation GO:0042594 47 27 0,000 0,12747664 0,15228628 ! response to toxin GO:0009636 49 27 0,000 0,12747664 0,15221185 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,12747664 0,15213749 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,12747664 0,1520632 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,12747664 0,15198899 ! leukocyte proliferation GO:0070661 59 27 0,000 0,12747664 0,15191485 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13187402 0,15707861 ! protein amino acid acylation GO:0043543 59 28 0,000 0,13187402 0,15700206 ! vesicle docking GO:0048278 55 28 0,000 0,13187402 0,15692559 ! circadian rhythm GO:0007623 56 28 0,000 0,13187402 0,15684919 ! dendrite development GO:0016358 67 28 0,000 0,13187402 0,15677286 ! fat cell differentiation GO:0045444 57 28 0,000 0,13187402 0,15669661 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13187402 0,15662044 ! sperm motility GO:0030317 37 28 0,000 0,13187402 0,15654433 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13187402 0,1564683 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13187402 0,15639235 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13187402 0,15631647 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13187402 0,15624066 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13187402 0,15616492 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13187402 0,15608926 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13187402 0,15601367 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13187402 0,15593816 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13187402 0,15586272 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13187402 0,15578735 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,13624936 0,16087829 ! translational initiation GO:0006413 66 29 0,000 0,13624936 0,16080058 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,13624936 0,16072293 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,13624936 0,16064536 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,13624936 0,16056787 ! autophagy GO:0006914 47 29 0,000 0,13624936 0,16049045 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,13624936 0,1604131 ! primary neural tube formation GO:0014020 61 29 0,000 0,13624936 0,16033583 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,13624936 0,16025864 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,13624936 0,16018152 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,13624936 0,16010447 ! somitogenesis GO:0001756 52 29 0,000 0,13624936 0,1600275 ! synaptogenesis GO:0007416 46 29 0,000 0,13624936 0,1599506 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,13624936 0,15987377 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,13624936 0,15979702 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,13624936 0,15972034 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14060277 0,16474464 ! phenol metabolic process GO:0018958 56 30 0,000 0,14060277 0,16466566 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14060277 0,16458676 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14060277 0,16450794 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14060277 0,16442919 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,14060277 0,16435051 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,14060277 0,16427191 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14060277 0,16419339 ! acute-phase response GO:0006953 50 30 0,000 0,14060277 0,16411494 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14060277 0,16403657 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14060277 0,16395827 ! myofibril assembly GO:0030239 50 30 0,000 0,14060277 0,16388004 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14060277 0,16380189 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14060277 0,16372382 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14060277 0,16364582 ! cell fate determination GO:0001709 64 30 0,000 0,14060277 0,16356789 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,14060277 0,16349004 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14060277 0,16341226 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14060277 0,16333456 GO:0046496|nicotinamide nucleotide metabolic process, ! regulation of coagulation GO:0050818 52 30 0,000 0,14060277 0,16325693 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,14493436 0,16820648 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,14493436 0,16812661 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,14493436 0,16804682 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,14493436 0,1679671 ! regulation of innate immune response GO:0045088 57 31 0,000 0,14493436 0,16788746 ! ovulation cycle process GO:0022602 55 31 0,000 0,14493436 0,16780789 ! detection of light stimulus GO:0009583 44 31 0,000 0,14493436 0,1677284 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,14493436 0,16764898 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,14493436 0,16756964 ! natural killer cell activation GO:0030101 50 31 0,000 0,14493436 0,16749037 ! cofactor catabolic process GO:0051187 54 31 0,000 0,14493436 0,16741118 ! eye morphogenesis GO:0048592 65 31 0,000 0,14493436 0,16733206 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,14493436 0,16725302 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,14924424 0,17214527 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,14924424 0,17206403 ! collagen metabolic process GO:0032963 49 32 0,000 0,14924424 0,17198287 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,14924424 0,17190178 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,14924424 0,17182077 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,14924424 0,17173984 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,14924424 0,17165898 ! muscle cell development GO:0055001 52 32 0,000 0,14924424 0,1715782 ! mesoderm formation GO:0001707 73 32 0,000 0,14924424 0,1714975 ! ovulation cycle GO:0042698 57 32 0,000 0,14924424 0,17141687 ! BMP signaling pathway GO:0030509 71 32 0,000 0,14924424 0,17133632 ! hindbrain development GO:0030902 65 32 0,000 0,14924424 0,17125584 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,14924424 0,17117544 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,14924424 0,17109511 ! gene silencing GO:0016458 71 32 0,000 0,14924424 0,17101486 ! regulation of pH GO:0006885 56 33 0,000 0,15353252 0,1758462 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15353252 0,1757638 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15353252 0,17568147 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,15353252 0,17559922 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15353252 0,17551705 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15353252 0,17543496 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,15353252 0,17535294 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15353252 0,175271 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15353252 0,17518914 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15353252 0,17510735 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,1577993 0,17988973 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1577993 0,17980583 ! spliceosome assembly GO:0000245 75 34 0,000 0,1577993 0,179722 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1577993 0,17963825 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1577993 0,17955458 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1577993 0,17947099 ! cell fate specification GO:0001708 56 34 0,000 0,1577993 0,17938748 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,1577993 0,17930404 ! adult locomotory behavior GO:0008344 62 34 0,000 0,1577993 0,17922068 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,1577993 0,1791374 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16204469 0,18387143 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16204469 0,18378607 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,16204469 0,18370078 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,16204469 0,18361558 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16204469 0,18353045 ! membrane docking GO:0022406 69 35 0,000 0,16204469 0,18344541 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16204469 0,18336044 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16204469 0,18327555 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,16204469 0,18319074 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16204469 0,18310601 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16204469 0,18302135 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16204469 0,18293678 ! telencephalon development GO:0021537 81 35 0,000 0,16204469 0,18285228 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,16204469 0,18276786 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16204469 0,18268352 ! vesicle localization GO:0051648 70 35 0,000 0,16204469 0,18259926 ! regulation of muscle development GO:0048634 82 36 0,000 0,16626881 0,1872728 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,16626881 0,18718649 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,16626881 0,18710027 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,16626881 0,18701413 ! protein targeting to membrane GO:0006612 75 36 0,000 0,16626881 0,18692807 ! regulation of proteolysis GO:0030162 77 36 0,000 0,16626881 0,18684209 ! aerobic respiration GO:0009060 56 36 0,000 0,16626881 0,18675618 ! embryonic organ development GO:0048568 67 36 0,000 0,16626881 0,18667036 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,16626881 0,18658461 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17047174 0,19121325 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,17047174 0,1911255 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17047174 0,19103783 ! tissue remodeling GO:0048771 78 37 0,000 0,17047174 0,19095024 ! female gonad development GO:0008585 71 37 0,000 0,17047174 0,19086273 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17047174 0,19077529 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,17047174 0,19068794 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,17465361 0,19527632 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,17465361 0,19518699 ! organic anion transport GO:0015711 82 38 0,000 0,17465361 0,19509775 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,17465361 0,19500858 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,17465361 0,19491949 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,17465361 0,19483049 ! spermatid development GO:0007286 69 38 0,000 0,17465361 0,19474157 ! glycogen metabolic process GO:0005977 63 38 0,000 0,17465361 0,19465272 ! pigment metabolic process GO:0042440 87 38 0,000 0,17465361 0,19456396 ! neural tube formation GO:0001841 79 38 0,000 0,17465361 0,19447528 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,17881451 0,1990177 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,17881451 0,19892707 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,17881451 0,19883653 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,17881451 0,19874607 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,17881451 0,19865569 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,17881451 0,19856539 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,17881451 0,19847517 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,17881451 0,19838504 ! glucan metabolic process GO:0044042 64 39 0,000 0,17881451 0,19829499 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,18295455 0,202794 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18295455 0,20270203 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,18295455 0,20261014 GO:0046660|female sex differentiation, ! RNA export from nucleus GO:0006405 61 41 0,000 0,18707384 0,20707811 ! mRNA catabolic process GO:0006402 79 41 0,000 0,18707384 0,20698433 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,18707384 0,20689063 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,18707384 0,20679701 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,18707384 0,20670348 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,18707384 0,20661003 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,18707384 0,20651667 ! feeding behavior GO:0007631 69 41 0,000 0,18707384 0,20642339 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,18707384 0,2063302 ! mesenchymal cell development GO:0014031 94 41 0,000 0,18707384 0,20623709 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,18707384 0,20614407 ! spermatid differentiation GO:0048515 73 41 0,000 0,18707384 0,20605112 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,18707384 0,20595827 ! RNA modification GO:0009451 64 41 0,000 0,18707384 0,20586549 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19117247 0,21028111 ! T cell differentiation GO:0030217 93 42 0,000 0,19117247 0,21018648 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19117247 0,21009193 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19117247 0,20999746 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19117247 0,20990308 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,19117247 0,20980878 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,19525056 0,2141882 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,19525056 0,21409206 ! regulation of tube size GO:0035150 76 43 0,000 0,19525056 0,21399601 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,19525056 0,21390005 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,19525056 0,21380417 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,19525056 0,21370838 ! segmentation GO:0035282 78 43 0,000 0,19525056 0,21361268 ! neuron migration GO:0001764 85 43 0,000 0,19525056 0,21351706 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,19930819 0,21785679 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,19930819 0,21775936 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,19930819 0,21766201 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,19930819 0,21756475 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,19930819 0,21746758 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,19930819 0,2173705 ! striated muscle contraction GO:0006941 85 44 0,000 0,19930819 0,2172735 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,19930819 0,21717659 ! double-strand break repair GO:0006302 85 44 0,000 0,19930819 0,21707977 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,20334549 0,22137835 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,20334549 0,22127974 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,20334549 0,22118122 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,20334549 0,22108279 ! B cell differentiation GO:0030183 124 45 0,000 0,20334549 0,22098444 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,20334549 0,22088618 ! female gamete generation GO:0007292 71 45 0,000 0,20334549 0,22078801 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,20334549 0,22068992 ! polyol metabolic process GO:0019751 77 45 0,000 0,20334549 0,22059193 ! developmental growth GO:0048589 88 45 0,000 0,20334549 0,22049402 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,20736253 0,22475007 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,20736253 0,22465041 ! glycolysis GO:0006096 71 46 0,000 0,20736253 0,22455083 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,20736253 0,22445134 ! leukocyte migration GO:0050900 75 46 0,000 0,20736253 0,22435193 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,20736253 0,22425262 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,20736253 0,22415339 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,20736253 0,22405425 ! neural tube development GO:0021915 91 47 0,000 0,21135944 0,22827193 ! positive regulation of defense response GO:0031349 88 48 0,000 0,2153363 0,23246424 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,2153363 0,23236156 ! mitochondrial transport GO:0006839 94 48 0,000 0,2153363 0,23225897 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,2153363 0,23215648 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,2153363 0,23205407 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,2153363 0,23195175 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,2153363 0,23184953 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,2153363 0,23174739 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,2153363 0,23164534 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,2153363 0,23154339 ! methylation GO:0032259 97 48 0,000 0,2153363 0,23144152 ! response to calcium ion GO:0051592 94 49 0,000 0,21929322 0,23559073 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,21929322 0,23548718 ! protein homooligomerization GO:0051260 84 49 0,000 0,21929322 0,23538371 ! regulation of ion transport GO:0043269 86 50 0,000 0,22323029 0,23950444 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,22323029 0,2393993 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,22323029 0,23929426 ! regulation of ossification GO:0030278 123 50 0,000 0,22323029 0,2391893 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,22323029 0,23908444 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,22323029 0,23897967 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,22323029 0,23887499 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,22323029 0,23877041 ! viral infectious cycle GO:0019058 104 51 0,000 0,22714763 0,24285411 ! peptide metabolic process GO:0006518 80 51 0,000 0,22714763 0,24274788 ! positive regulation of binding GO:0051099 88 52 0,000 0,23104531 0,24680529 ! Notch signaling pathway GO:0007219 111 52 0,000 0,23104531 0,24669742 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,23104531 0,24658964 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,23104531 0,24648196 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,23104531 0,24637438 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,23104531 0,24626688 ! excretion GO:0007588 87 52 0,000 0,23104531 0,24615948 ! histone modification GO:0016570 104 52 0,000 0,23104531 0,24605218 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,23104531 0,24594497 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,23104531 0,24583785 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,23104531 0,24573082 ! amino acid activation GO:0043038 98 52 0,000 0,23104531 0,24562389 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,23492345 0,2496381 ! chromatin remodeling GO:0006338 122 53 0,000 0,23492345 0,24952956 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,23492345 0,24942112 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,23492345 0,24931277 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,23492345 0,24920451 ! cartilage development GO:0051216 99 53 0,000 0,23492345 0,24909635 ! regulation of translational initiation GO:0006446 87 54 0,000 0,23878214 0,25307799 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,23878214 0,25296824 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,23878214 0,25285859 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,23878214 0,25274903 ! membrane fusion GO:0006944 122 54 0,000 0,23878214 0,25263957 ! covalent chromatin modification GO:0016569 115 54 0,000 0,23878214 0,2525302 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,23878214 0,25242093 ! regulation of cell shape GO:0008360 142 54 0,000 0,23878214 0,25231175 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,23878214 0,25220267 ! RNA catabolic process GO:0006401 103 55 0,000 0,24262147 0,25614704 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,24262147 0,2560364 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,24262147 0,25592585 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,24262147 0,25581539 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,24262147 0,25570503 ! cell maturation GO:0048469 107 55 0,000 0,24262147 0,25559476 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,24262147 0,25548459 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,24644155 0,25939539 ! glucose catabolic process GO:0006007 88 56 0,000 0,24644155 0,25928368 ! RNA elongation GO:0006354 90 56 0,000 0,24644155 0,25917207 ! chloride transport GO:0006821 102 57 0,000 0,25024247 0,26305609 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,25024247 0,26294295 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,25024247 0,2628299 ! heart morphogenesis GO:0003007 105 57 0,000 0,25024247 0,26271695 ! regulation of actin filament length GO:0030832 118 58 0,000 0,25402432 0,26657277 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,25402432 0,26645832 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,25402432 0,26634396 ! gastrulation GO:0007369 122 58 0,000 0,25402432 0,26622969 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,25402432 0,26611553 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,25402432 0,26600147 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,25402432 0,2658875 ! nuclear export GO:0051168 110 59 0,000 0,2577872 0,26971055 ! regulation of endocytosis GO:0030100 104 60 0,000 0,26153121 0,27351059 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,26153121 0,27339356 ! adult behavior GO:0030534 104 60 0,000 0,26153121 0,27327662 ! positive regulation of secretion GO:0051047 110 61 0,000 0,26525644 0,27705065 ! regulation of cellular component size GO:0032535 125 61 0,000 0,26525644 0,27693225 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,26525644 0,27681396 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,26525644 0,27669576 ! regulation of heart contraction GO:0008016 123 61 0,000 0,26525644 0,27657767 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,26525644 0,27645967 ! viral reproductive process GO:0022415 132 62 0,000 0,26896298 0,28020322 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,26896298 0,28008378 ! tRNA processing GO:0008033 102 62 0,000 0,26896298 0,27996444 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,27265092 0,28368237 ! mesoderm development GO:0007498 128 63 0,000 0,27265092 0,2835616 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,27632036 0,28725559 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,27632036 0,28713341 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,27997139 0,29080362 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,27997139 0,29068003 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,27997139 0,29055655 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,27997139 0,29043317 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,28360411 0,29407676 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,2872186 0,29769836 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,2872186 0,29757211 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,2872186 0,29744597 ! secondary metabolic process GO:0019748 125 67 0,000 0,2872186 0,29731993 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,29081495 0,30091526 ! hexose catabolic process GO:0019320 113 68 0,000 0,29081495 0,30078786 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,29081495 0,30066057 ! viral reproduction GO:0016032 142 68 0,000 0,29081495 0,30053339 ! regulation of lipase activity GO:0060191 137 68 0,000 0,29081495 0,30040631 ! adaptive immune response GO:0002250 126 68 0,000 0,29081495 0,30027935 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,29081495 0,30015249 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,29439326 0,30371738 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,29439326 0,30358917 ! developmental maturation GO:0021700 128 69 0,000 0,29439326 0,30346107 ! single fertilization GO:0007338 83 69 0,000 0,29439326 0,30333309 ! cell redox homeostasis GO:0045454 114 70 0,000 0,29795362 0,30687213 ! activation of immune response GO:0002253 120 70 0,000 0,29795362 0,30674281 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,29795362 0,3066136 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,30149611 0,31012842 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,30149611 0,30999789 ! appendage morphogenesis GO:0035107 150 72 0,000 0,30502082 0,31349006 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 0,000 0,30502082 0,31335823 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,30502082 0,31322651 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,30502082 0,31309491 ! appendage development GO:0048736 151 73 0,000 0,30852785 0,31656176 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,30852785 0,31642886 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,30852785 0,31629607 ! regulation of immune effector process GO:0002697 156 73 0,000 0,30852785 0,3161634 ! acute inflammatory response GO:0002526 118 74 0,000 0,31201728 0,31960512 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,31201728 0,31947117 ! transition metal ion transport GO:0000041 143 75 0,000 0,3154892 0,3228907 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,3154892 0,32275549 ! rhythmic process GO:0048511 142 75 0,000 0,3154892 0,32262039 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,31894369 0,3260165 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,31894369 0,32588015 ! regulation of blood pressure GO:0008217 134 76 0,000 0,31894369 0,32574391 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,31894369 0,32560779 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,32238085 0,32897929 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,32238085 0,32884193 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,32238085 0,32870468 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,32238085 0,32856755 ! antigen processing and presentation GO:0019882 117 78 0,000 0,32580075 0,33191461 ! fertilization GO:0009566 99 78 0,000 0,32580075 0,33177626 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,32580075 0,33163802 ! blood coagulation GO:0007596 151 79 0,000 0,3292035 0,33496216 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,3292035 0,33482271 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,3292035 0,33468337 ! protein oligomerization GO:0051259 149 79 0,000 0,3292035 0,33454415 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,3292035 0,33440505 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,33595783 0,34112427 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,33595783 0,34098254 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,34264453 0,34762483 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,34264453 0,34748053 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,34264453 0,34733635 ! inorganic anion transport GO:0015698 156 83 0,000 0,34264453 0,34719228 ! T cell activation GO:0042110 189 84 0,000 0,34596273 0,35040918 ! response to nutrient GO:0007584 135 84 0,000 0,34596273 0,35026397 ! digestion GO:0007586 130 84 0,000 0,34596273 0,35011887 ! hemostasis GO:0007599 165 85 0,000 0,34926427 0,35331371 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,34926427 0,35316747 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,34926427 0,35302136 ! regulation of lyase activity GO:0051339 169 86 0,000 0,35254924 0,35619429 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,35254924 0,35604704 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,35581772 0,35919946 ! alcohol catabolic process GO:0046164 142 87 0,000 0,35581772 0,35905109 ! nucleosome assembly GO:0006334 126 87 0,000 0,35581772 0,35890284 ! cellular respiration GO:0045333 143 88 0,000 0,35906979 0,36203363 ! amine biosynthetic process GO:0009309 146 88 0,000 0,35906979 0,36188428 ! sensory perception of smell GO:0007608 117 88 0,000 0,35906979 0,36173505 ! chromatin assembly GO:0031497 128 88 0,000 0,35906979 0,36158594 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,35906979 0,36143696 ! tube morphogenesis GO:0035239 194 89 0,000 0,36230553 0,36454383 ! cellular defense response GO:0006968 123 89 0,000 0,36230553 0,36439375 ! regulation of neurological system process GO:0031644 175 89 0,000 0,36230553 0,36424379 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,36552503 0,36732935 ! defense response to bacterium GO:0042742 112 91 0,000 0,36872836 0,37039613 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,37191562 0,37344425 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,37508686 0,37647379 ! regulation of defense response GO:0031347 171 95 0,000 0,38138167 0,38263467 ! nucleosome organization GO:0034728 143 95 0,000 0,38138167 0,3824776 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,38138167 0,38232065 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,38138167 0,38216383 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,38138167 0,38200714 ! leukocyte differentiation GO:0002521 232 98 0,000 0,39070585 0,39118622 ! mRNA transport GO:0051028 185 100 0,000 0,39684419 0,39716934 ! positive regulation of immune response GO:0050778 175 100 0,000 0,39684419 0,3970067 ! hormone metabolic process GO:0042445 171 100 0,000 0,39684419 0,39684419