pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6312-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell-substrate junction assembly GO:0007044 11 10 3,000 2,006E-07 3,698E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 3,000 4,69E-07 4,322E-04 ! peptidyl-amino acid modification GO:0018193 61 59 5,000 9,392E-07 5,77E-04 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 3,000 2,208E-06 1,017E-03 ! cell junction assembly GO:0034329 18 17 3,000 2,208E-06 8,139E-04 ! cell-matrix adhesion GO:0007160 39 38 4,000 2,238E-06 6,874E-04 ! regulation of cell migration GO:0030334 71 71 5,000 2,837E-06 7,469E-04 ! N-terminal protein amino acid modification GO:0031365 6 6 2,000 3,598E-06 8,29E-04 GO:0018409|peptide or protein amino-terminal blocking, ! focal adhesion formation GO:0048041 7 6 2,000 3,598E-06 7,368E-04 ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 3,598E-06 6,632E-04 ! cell-substrate adhesion GO:0031589 43 42 4,000 3,729E-06 6,247E-04 ! regulation of locomotion GO:0040012 79 79 5,000 5,321E-06 8,173E-04 ! regulation of cell motion GO:0051270 79 79 5,000 5,321E-06 7,544E-04 ! tube development GO:0035295 83 81 5,000 6,16E-06 8,109E-04 ! cell junction organization GO:0034330 23 22 3,000 6,646E-06 8,166E-04 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 5,000 8,736E-06 1,006E-03 ! negative regulation of bone remodeling GO:0046851 8 8 2,000 9,994E-06 1,083E-03 ! negative regulation of mitotic cell cycle GO:0045930 9 8 2,000 9,994E-06 1,023E-03 ! peptidyl-serine modification GO:0018209 8 8 2,000 9,994E-06 9,694E-04 ! negative regulation of tissue remodeling GO:0034104 9 9 2,000 1,493E-05 1,376E-03 ! posttranscriptional regulation of gene expression GO:0010608 98 98 5,000 1,858E-05 1,631E-03 ! negative regulation of homeostatic process GO:0032845 10 10 2,000 2,124E-05 1,78E-03 ! hindbrain development GO:0030902 11 11 2,000 2,909E-05 2,331E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 2,000 5,002E-05 3,841E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 5,047E-05 3,72E-03 ! lung development GO:0030324 38 37 3,000 5,635E-05 3,994E-03 ! protein amino acid acylation GO:0043543 14 14 2,000 6,341E-05 4,328E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 6,341E-05 4,173E-03 ! respiratory tube development GO:0030323 40 39 3,000 6,959E-05 4,422E-03 ! respiratory system development GO:0060541 40 39 3,000 6,959E-05 4,275E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 6,959E-05 4,137E-03 ! response to protein stimulus GO:0051789 42 42 3,000 9,352E-05 5,386E-03 ! pigmentation GO:0043473 17 17 2,000 1,17E-04 6,536E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,266E-04 6,863E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 1,399E-04 7,365E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,412E-04 7,229E-03 GO:0033674|positive regulation of kinase activity, ! actin filament organization GO:0007015 50 48 3,000 1,585E-04 7,897E-03 ! regulation of protein stability GO:0031647 19 19 2,000 1,654E-04 8,023E-03 ! response to heat GO:0009408 19 19 2,000 1,654E-04 7,817E-03 ! ossification GO:0001503 50 49 3,000 1,719E-04 7,921E-03 GO:0060348|bone development, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,719E-04 7,727E-03 ! chromatin remodeling GO:0006338 20 20 2,000 1,938E-04 8,505E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 2,011E-04 8,618E-03 GO:0051325|interphase, ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 2,252E-04 9,434E-03 ! response to hypoxia GO:0001666 53 53 3,000 2,336E-04 9,569E-03 ! response to oxygen levels GO:0070482 55 54 3,000 2,513E-04 0,0100675 ! metencephalon development GO:0022037 5 5 1,000 3,26E-04 0,01278299 ! mRNA stabilization GO:0048255 5 5 1,000 3,26E-04 0,01251667 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 3,26E-04 0,01226123 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,26E-04 0,01201601 ! fear response GO:0042596 5 5 1,000 3,26E-04 0,0117804 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 3,26E-04 0,01155385 ! response to UV-B GO:0010224 5 5 1,000 3,26E-04 0,01133586 ! neuron recognition GO:0008038 5 5 1,000 3,26E-04 0,01112593 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 3,26E-04 0,01092364 ! cellular pigmentation GO:0033059 5 5 1,000 3,26E-04 0,01072858 ! T cell lineage commitment GO:0002360 5 5 1,000 3,26E-04 0,01054036 ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,26E-04 0,01035863 ! oocyte differentiation GO:0009994 5 5 1,000 3,26E-04 0,01018306 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 3,26E-04 0,01001334 ! spleen development GO:0048536 5 5 1,000 3,26E-04 9,849E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 3,26E-04 9,69E-03 ! response to nicotine GO:0035094 5 5 1,000 3,26E-04 9,537E-03 ! axonogenesis GO:0007409 66 62 3,000 4,286E-04 0,0123437 ! negative regulation of cell migration GO:0030336 26 26 2,000 4,315E-04 0,01223486 ! angiogenesis GO:0001525 65 64 3,000 4,842E-04 0,01351967 ! negative regulation of cellular catabolic process GO:0031330 6 6 1,000 4,872E-04 0,01340126 ! cartilage condensation GO:0001502 7 6 1,000 4,872E-04 0,01320419 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 4,872E-04 0,01301282 GO:0050927|positive regulation of positive chemotaxis, ! L-serine metabolic process GO:0006563 6 6 1,000 4,872E-04 0,01282692 ! ER overload response GO:0006983 6 6 1,000 4,872E-04 0,01264626 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,872E-04 0,01247062 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 4,872E-04 0,01229979 ! negative regulation of ossification GO:0030279 6 6 1,000 4,872E-04 0,01213358 ! regulation of bone resorption GO:0045124 6 6 1,000 4,872E-04 0,0119718 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 4,872E-04 0,01181427 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,872E-04 0,01166084 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,872E-04 0,01151134 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 4,872E-04 0,01136563 ! thymus development GO:0048538 6 6 1,000 4,872E-04 0,01122356 ! localization within membrane GO:0051668 6 6 1,000 4,872E-04 0,011085 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 5,393E-04 0,01212189 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 5,446E-04 0,01209304 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 5,768E-04 0,01265473 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! branching morphogenesis of a tube GO:0048754 29 29 2,000 5,991E-04 0,01299095 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 5,991E-04 0,01283989 ! response to UV GO:0009411 29 29 2,000 5,991E-04 0,0126923 ! response to radiation GO:0009314 70 68 3,000 6,103E-04 0,01278093 ! skeletal system morphogenesis GO:0048705 31 30 2,000 6,63E-04 0,01373025 ! response to temperature stimulus GO:0009266 30 30 2,000 6,63E-04 0,01357769 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 6,796E-04 0,0137628 ! cellular protein complex disassembly GO:0043624 8 7 1,000 6,796E-04 0,01361321 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 1,000 6,796E-04 0,01346683 ! digestive system development GO:0055123 7 7 1,000 6,796E-04 0,01332357 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 6,796E-04 0,01318332 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 6,796E-04 0,01304599 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 6,796E-04 0,0129115 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 6,796E-04 0,01277975 ! cranial nerve development GO:0021545 7 7 1,000 6,796E-04 0,01265066 ! induction of an organ GO:0001759 7 7 1,000 6,796E-04 0,01252415 ! autonomic nervous system development GO:0048483 7 7 1,000 6,796E-04 0,01240015 ! response to gamma radiation GO:0010332 8 7 1,000 6,796E-04 0,01227858 ! regulation of mRNA stability GO:0043488 7 7 1,000 6,796E-04 0,01215937 ! regulation of axon extension GO:0030516 7 7 1,000 6,796E-04 0,01204245 ! negative regulation of T cell activation GO:0050868 7 7 1,000 6,796E-04 0,01192776 ! cell part morphogenesis GO:0032990 75 70 3,000 6,814E-04 0,01184672 ! aging GO:0007568 32 31 2,000 7,311E-04 0,01259331 ! negative regulation of cell motion GO:0051271 31 31 2,000 7,311E-04 0,01247671 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 8,035E-04 0,01358629 ! regulation of neuron differentiation GO:0045664 34 33 2,000 8,803E-04 0,01474958 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 9,027E-04 0,01498871 ! T cell selection GO:0045058 8 8 1,000 9,027E-04 0,01485489 ! negative regulation of proteolysis GO:0045861 8 8 1,000 9,027E-04 0,01472343 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 9,027E-04 0,01459427 ! alpha-beta T cell activation GO:0046631 8 8 1,000 9,027E-04 0,01446737 ! T cell homeostasis GO:0043029 8 8 1,000 9,027E-04 0,01434265 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 9,027E-04 0,01422006 ! regulation of RNA stability GO:0043487 8 8 1,000 9,027E-04 0,01409955 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 9,027E-04 0,01398107 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 9,027E-04 0,01386456 ! developmental induction GO:0031128 8 8 1,000 9,027E-04 0,01374998 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of angiogenesis GO:0045765 35 34 2,000 9,616E-04 0,01452721 ! regulation of bone remodeling GO:0046850 34 34 2,000 9,616E-04 0,0144091 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 9,616E-04 0,0142929 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 9,767E-04 0,01439977 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,048E-03 0,01532294 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 1,048E-03 0,01520229 ! regulation of tissue remodeling GO:0034103 35 35 2,000 1,048E-03 0,01508352 ! neuron projection development GO:0031175 85 80 3,000 1,127E-03 0,01610416 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 1,138E-03 0,01613656 ! cortical actin cytoskeleton organization GO:0030866 10 9 1,000 1,156E-03 0,01626902 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,156E-03 0,01614577 ! response to alkaloid GO:0043279 10 9 1,000 1,156E-03 0,01602437 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,156E-03 0,01590479 ! response to ethanol GO:0045471 9 9 1,000 1,156E-03 0,01578697 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,156E-03 0,01567089 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,156E-03 0,01555651 ! pigmentation during development GO:0048066 9 9 1,000 1,156E-03 0,01544378 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,156E-03 0,01533267 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,156E-03 0,01522315 ! histone acetylation GO:0016573 9 9 1,000 1,156E-03 0,01511519 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,156E-03 0,01500874 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,156E-03 0,01490379 ! defense response to virus GO:0051607 9 9 1,000 1,156E-03 0,01480029 ! response to drug GO:0042493 37 37 2,000 1,234E-03 0,01568059 ! blood vessel morphogenesis GO:0048514 84 83 3,000 1,293E-03 0,01632667 ! axon guidance GO:0007411 39 38 2,000 1,334E-03 0,01672561 ! regulation of homeostatic process GO:0032844 38 38 2,000 1,334E-03 0,0166126 ! response to unfolded protein GO:0006986 39 39 2,000 1,439E-03 0,01780447 ! cortical cytoskeleton organization GO:0030865 11 10 1,000 1,44E-03 0,01769509 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,44E-03 0,01757791 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,44E-03 0,01746226 ! epidermis morphogenesis GO:0048730 10 10 1,000 1,44E-03 0,01734813 ! neuromuscular junction development GO:0007528 10 10 1,000 1,44E-03 0,01723548 ! regulation of protein binding GO:0043393 11 10 1,000 1,44E-03 0,01712428 ! gland morphogenesis GO:0022612 10 10 1,000 1,44E-03 0,01701451 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,44E-03 0,01690614 ! nerve development GO:0021675 10 10 1,000 1,44E-03 0,01679914 ! gut development GO:0048565 10 10 1,000 1,44E-03 0,01669348 ! heart development GO:0007507 90 87 3,000 1,541E-03 0,01774703 ! cell cycle checkpoint GO:0000075 42 41 2,000 1,666E-03 0,01906587 ! brain development GO:0007420 91 90 3,000 1,747E-03 0,01987056 ! endothelial cell migration GO:0043542 11 11 1,000 1,754E-03 0,01982936 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,754E-03 0,01970845 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 1,754E-03 0,019589 GO:0032388|positive regulation of intracellular transport, ! dendrite development GO:0016358 11 11 1,000 1,754E-03 0,019471 ! regulation of viral genome replication GO:0045069 11 11 1,000 1,754E-03 0,0193544 ! activation of MAPKK activity GO:0000186 12 11 1,000 1,754E-03 0,0192392 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,754E-03 0,01912536 ! cellular macromolecular complex disassembly GO:0034623 12 11 1,000 1,754E-03 0,01901286 ! mitotic spindle organization GO:0007052 11 11 1,000 1,754E-03 0,01890167 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,754E-03 0,01879178 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,754E-03 0,01868315 ! oogenesis GO:0048477 11 11 1,000 1,754E-03 0,01857578 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,754E-03 0,01846963 ! negative regulation of cell cycle GO:0045786 92 91 3,000 1,819E-03 0,01905118 ! blood vessel development GO:0001568 95 94 3,000 2,05E-03 0,02134556 ! pattern specification process GO:0007389 96 94 3,000 2,05E-03 0,02122564 ! epidermis development GO:0008544 94 94 3,000 2,05E-03 0,02110706 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 2,097E-03 0,02146879 ! heterophilic cell adhesion GO:0007157 12 12 1,000 2,097E-03 0,02135018 ! collagen metabolic process GO:0032963 12 12 1,000 2,097E-03 0,02123287 ! male gonad development GO:0008584 12 12 1,000 2,097E-03 0,02111684 ! renal system process GO:0003014 12 12 1,000 2,097E-03 0,02100208 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 2,097E-03 0,02088855 ! somitogenesis GO:0001756 13 12 1,000 2,097E-03 0,02077625 ! negative regulation of translation GO:0017148 12 12 1,000 2,097E-03 0,02066515 ! regulation of cell growth GO:0001558 97 96 3,000 2,215E-03 0,02171023 ! vasculature development GO:0001944 97 96 3,000 2,215E-03 0,02159536 ! tube morphogenesis GO:0035239 47 46 2,000 2,325E-03 0,02254863 ! regulation of membrane potential GO:0042391 46 46 2,000 2,325E-03 0,02243058 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 2,469E-03 0,02369915 ! regeneration GO:0031099 13 13 1,000 2,469E-03 0,02357635 ! post-embryonic development GO:0009791 14 13 1,000 2,469E-03 0,02345482 ! patterning of blood vessels GO:0001569 13 13 1,000 2,469E-03 0,02333454 ! vasculogenesis GO:0001570 13 13 1,000 2,469E-03 0,02321549 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,469E-03 0,02309764 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,469E-03 0,02298099 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 2,469E-03 0,02286551 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 2,469E-03 0,02275118 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 2,469E-03 0,02263799 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 2,469E-03 0,02252592 ! ureteric bud development GO:0001657 13 13 1,000 2,469E-03 0,02241496 ! cell aging GO:0007569 13 13 1,000 2,469E-03 0,02230508 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,469E-03 0,02219627 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,469E-03 0,02208852 ! regulation of viral reproduction GO:0050792 13 13 1,000 2,469E-03 0,02198182 ! regulation of axonogenesis GO:0050770 14 13 1,000 2,469E-03 0,02187613 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,469E-03 0,02177146 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,469E-03 0,02166779 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 2,469E-03 0,0215651 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 2,469E-03 0,02146338 ! tissue homeostasis GO:0001894 13 13 1,000 2,469E-03 0,02136261 GO:0048871|multicellular organismal homeostasis, ! anti-apoptosis GO:0006916 100 99 3,000 2,478E-03 0,02134381 ! ectoderm development GO:0007398 99 99 3,000 2,478E-03 0,02124453 ! gland development GO:0048732 51 49 2,000 2,788E-03 0,02378493 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,788E-03 0,02367532 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 2,788E-03 0,02356672 ! regulation of neuron projection development GO:0010975 15 14 1,000 2,87E-03 0,02415129 ! macromolecular complex disassembly GO:0032984 15 14 1,000 2,87E-03 0,02404151 ! hair cycle GO:0042633 14 14 1,000 2,87E-03 0,02393273 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! response to retinoic acid GO:0032526 14 14 1,000 2,87E-03 0,02382492 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 1,000 2,87E-03 0,02371808 ! regulation of behavior GO:0050795 14 14 1,000 2,87E-03 0,0236122 ! response to organic cyclic substance GO:0014070 15 14 1,000 2,87E-03 0,02350725 ! regulation of neurogenesis GO:0050767 51 50 2,000 2,954E-03 0,02408665 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 2,954E-03 0,02398054 ! response to vitamin GO:0033273 15 15 1,000 3,299E-03 0,0266687 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 3,299E-03 0,02655224 ! ovarian follicle development GO:0001541 15 15 1,000 3,299E-03 0,0264368 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,299E-03 0,02632235 ! response to ionizing radiation GO:0010212 16 15 1,000 3,299E-03 0,02620889 ! leukocyte homeostasis GO:0001776 15 15 1,000 3,299E-03 0,02609641 ! negative regulation of cell activation GO:0050866 15 15 1,000 3,299E-03 0,02598488 ! cell fate commitment GO:0045165 52 52 2,000 3,304E-03 0,02591006 ! response to light stimulus GO:0009416 53 52 2,000 3,304E-03 0,02580027 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 3,678E-03 0,02860446 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 3,757E-03 0,02909086 ! segmentation GO:0035282 17 16 1,000 3,757E-03 0,02896914 ! positive regulation of cell development GO:0010720 16 16 1,000 3,757E-03 0,02884843 ! lymphocyte proliferation GO:0046651 16 16 1,000 3,757E-03 0,02872873 ! cell fate specification GO:0001708 16 16 1,000 3,757E-03 0,02861002 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 3,757E-03 0,02849228 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 3,757E-03 0,02837551 ! regulation of cell adhesion GO:0030155 56 55 2,000 3,875E-03 0,02914969 ! extracellular structure organization GO:0043062 56 56 2,000 4,078E-03 0,03055175 ! regulation of nervous system development GO:0051960 57 56 2,000 4,078E-03 0,03042806 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,242E-03 0,03152426 ! myelination GO:0042552 17 17 1,000 4,242E-03 0,03139766 ! leukocyte adhesion GO:0007159 17 17 1,000 4,242E-03 0,03127207 ! glucose transport GO:0015758 17 17 1,000 4,242E-03 0,03114748 ! tissue remodeling GO:0048771 17 17 1,000 4,242E-03 0,03102388 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 4,242E-03 0,03090125 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 4,242E-03 0,03077959 ! response to toxin GO:0009636 18 17 1,000 4,242E-03 0,03065889 ! negative regulation of cell development GO:0010721 18 17 1,000 4,242E-03 0,03053913 GO:0050768|negative regulation of neurogenesis, ! cell recognition GO:0008037 18 17 1,000 4,242E-03 0,0304203 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,242E-03 0,03030239 ! regulation of binding GO:0051098 60 57 2,000 4,287E-03 0,03050786 ! regulation of protein localization GO:0032880 58 57 2,000 4,287E-03 0,03039053 ! regulation of cell development GO:0060284 60 59 2,000 4,725E-03 0,0333672 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,755E-03 0,03344674 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 4,755E-03 0,03331957 ! meiosis I GO:0007127 18 18 1,000 4,755E-03 0,03319336 ! mononuclear cell proliferation GO:0032943 18 18 1,000 4,755E-03 0,0330681 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 4,755E-03 0,03294379 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 18 18 1,000 4,755E-03 0,0328204 ! ensheathment of neurons GO:0007272 18 18 1,000 4,755E-03 0,03269794 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 4,755E-03 0,03257638 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 4,954E-03 0,03381685 ! DNA damage checkpoint GO:0000077 19 19 1,000 5,295E-03 0,03600785 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 5,295E-03 0,03587546 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 5,295E-03 0,03574405 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 5,295E-03 0,0356136 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 5,295E-03 0,0354841 ! metanephros development GO:0001656 19 19 1,000 5,295E-03 0,03535553 ! peripheral nervous system development GO:0007422 19 19 1,000 5,295E-03 0,03522789 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 5,295E-03 0,03510117 ! regulation of cell shape GO:0008360 21 19 1,000 5,295E-03 0,03497536 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 5,432E-03 0,03575211 GO:0060429|epithelium development, ! regulation of muscle development GO:0048634 21 20 1,000 5,861E-03 0,03844367 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 5,861E-03 0,03830734 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 5,861E-03 0,03817198 ! female gamete generation GO:0007292 20 20 1,000 5,861E-03 0,03803757 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 5,861E-03 0,03790411 ! mammary gland development GO:0030879 23 21 1,000 6,455E-03 0,04159475 ! protein amino acid lipidation GO:0006497 21 21 1,000 6,455E-03 0,04144983 ! DNA integrity checkpoint GO:0031570 21 21 1,000 6,455E-03 0,0413059 ! regulation of action potential in neuron GO:0019228 21 21 1,000 6,455E-03 0,04116298 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 6,455E-03 0,04102103 ! regulation of proteolysis GO:0030162 21 21 1,000 6,455E-03 0,04088007 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 6,455E-03 0,04074007 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 6,468E-03 0,04068205 ! striated muscle tissue development GO:0014706 69 67 2,000 6,744E-03 0,04227468 ! Ras protein signal transduction GO:0007265 69 67 2,000 6,744E-03 0,04213138 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 7,074E-03 0,04404676 GO:0090047|positive regulation of transcription regulator activity, ! embryonic skeletal system development GO:0048706 22 22 1,000 7,074E-03 0,04389845 ! ovulation cycle process GO:0022602 22 22 1,000 7,074E-03 0,04375114 ! spindle organization GO:0007051 22 22 1,000 7,074E-03 0,04360482 ! male sex differentiation GO:0046661 22 22 1,000 7,074E-03 0,04345947 ! regulation of translation GO:0006417 69 69 2,000 7,317E-03 0,04480098 ! regionalization GO:0003002 70 69 2,000 7,317E-03 0,04465263 ! response to nutrient levels GO:0031667 69 69 2,000 7,317E-03 0,04450527 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 7,317E-03 0,04435887 ! wound healing GO:0042060 74 70 2,000 7,614E-03 0,04600878 ! muscle tissue development GO:0060537 72 70 2,000 7,614E-03 0,04585842 ! response to hydrogen peroxide GO:0042542 24 23 1,000 7,72E-03 0,04634307 ! response to estrogen stimulus GO:0043627 23 23 1,000 7,72E-03 0,0461926 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 7,72E-03 0,04604311 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 7,72E-03 0,04589459 ! positive regulation of growth GO:0045927 23 23 1,000 7,72E-03 0,04574701 ! female gonad development GO:0008585 23 23 1,000 7,72E-03 0,04560039 ! calcium-mediated signaling GO:0019722 23 23 1,000 7,72E-03 0,0454547 ! response to extracellular stimulus GO:0009991 72 72 2,000 8,23E-03 0,04830269 ! mitochondrial transport GO:0006839 24 24 1,000 8,391E-03 0,049092 ! regulation of action potential GO:0001508 24 24 1,000 8,391E-03 0,04893664 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 8,391E-03 0,04878227 ! T cell differentiation GO:0030217 24 24 1,000 8,391E-03 0,04862886 ! ovulation cycle GO:0042698 24 24 1,000 8,391E-03 0,04847642 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 8,391E-03 0,04832493 ! glucan metabolic process GO:0044042 25 24 1,000 8,391E-03 0,04817439 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! cellular component disassembly GO:0022411 26 25 1,000 9,087E-03 0,0520101 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 9,087E-03 0,05184907 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 9,087E-03 0,05168905 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 9,087E-03 0,05153 ! positive regulation of DNA binding GO:0043388 26 25 1,000 9,087E-03 0,05137194 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 9,087E-03 0,05121483 ! negative regulation of immune system process GO:0002683 25 25 1,000 9,087E-03 0,05105869 ! JAK-STAT cascade GO:0007259 26 25 1,000 9,087E-03 0,0509035 ! positive regulation of binding GO:0051099 27 26 1,000 9,808E-03 0,05477752 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 9,808E-03 0,05461203 ! regulation of T cell differentiation GO:0045580 26 26 1,000 9,808E-03 0,05444754 ! germ cell development GO:0007281 27 26 1,000 9,808E-03 0,05428403 ! pigment metabolic process GO:0042440 26 26 1,000 9,808E-03 0,05412151 ! response to insulin stimulus GO:0032868 28 26 1,000 9,808E-03 0,05395995 ! synapse organization GO:0050808 26 26 1,000 9,808E-03 0,05379935 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01055422 0,05771936 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01055422 0,05754859 ! learning or memory GO:0007611 28 27 1,000 0,01055422 0,05737883 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01055422 0,05721007 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! carbohydrate transport GO:0008643 28 28 1,000 0,01132459 0,06120594 ! histone modification GO:0016570 28 28 1,000 0,01132459 0,06102698 ! developmental growth GO:0048589 28 28 1,000 0,01132459 0,06084905 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01132459 0,06067217 ! cartilage development GO:0051216 29 28 1,000 0,01132459 0,06049631 ! MAPKKK cascade GO:0000165 82 81 2,000 0,01135739 0,06049615 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01211907 0,06436728 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01211907 0,06418232 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,01211907 0,06399842 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01211907 0,06381556 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,01293736 0,06793035 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01293736 0,06773736 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01293736 0,06754547 ! regulation of ossification GO:0030278 30 30 1,000 0,01293736 0,06735467 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01293736 0,06716493 ! vesicle organization GO:0016050 30 30 1,000 0,01293736 0,06697627 ! regulation of translational initiation GO:0006446 31 31 1,000 0,01377917 0,07113447 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01377917 0,07093577 ! B cell activation GO:0042113 31 31 1,000 0,01377917 0,07073817 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,01377917 0,07054168 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01377917 0,07034627 ! extracellular matrix organization GO:0030198 31 31 1,000 0,01377917 0,07015195 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01377917 0,06995869 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01464421 0,07414637 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01464421 0,07394323 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01464421 0,0737412 ! muscle fiber development GO:0048747 32 32 1,000 0,01464421 0,07354027 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01464421 0,07334043 ! kidney development GO:0001822 32 32 1,000 0,01464421 0,07314167 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01464421 0,07294399 ! negative regulation of cell size GO:0045792 33 33 1,000 0,0155322 0,07715862 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,0155322 0,0769512 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,0155322 0,0767449 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,0155322 0,0765397 ! DNA replication GO:0006260 91 91 2,000 0,01553947 0,07637131 ! response to metal ion GO:0010038 34 34 1,000 0,01644286 0,08059626 ! ear development GO:0043583 34 34 1,000 0,01644286 0,08038247 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,01644286 0,08016982 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01644286 0,07995829 ! secondary metabolic process GO:0019748 34 34 1,000 0,01644286 0,07974787 ! tissue morphogenesis GO:0048729 94 93 2,000 0,01646704 0,07965553 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01737591 0,08383193 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01737591 0,08361305 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,01737591 0,08339531 ! response to inorganic substance GO:0010035 36 36 1,000 0,01833107 0,08775105 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,01833107 0,08752372 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01833107 0,08729756 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,01833107 0,08707256 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,01833107 0,08684873 ! gonad development GO:0008406 36 36 1,000 0,01833107 0,08662604 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01833107 0,08640449 ! blood circulation GO:0008015 99 98 2,000 0,01892043 0,08895499 GO:0003013|circulatory system process, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01930806 0,09054644 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,01930806 0,09031663 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,01930806 0,09008798 ! negative regulation of growth GO:0045926 37 37 1,000 0,01930806 0,08986049 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01930806 0,08963414 ! adaptive immune response GO:0002250 37 37 1,000 0,01930806 0,08940893 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! response to hormone stimulus GO:0009725 102 100 2,000 0,0199558 0,09217677 ! muscle organ development GO:0007517 102 100 2,000 0,0199558 0,09194633 ! hemopoiesis GO:0030097 104 100 2,000 0,0199558 0,09171703 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,02030661 0,09309724 ! urogenital system development GO:0001655 38 38 1,000 0,02030661 0,09286623 ! meiotic cell cycle GO:0051321 38 38 1,000 0,02030661 0,09263636 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02030661 0,09240763 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02132646 0,09680953 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,02132646 0,09657167 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,02236733 0,10103676 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,02451109 0,11044972 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02451109 0,11018033 ! reproductive structure development GO:0048608 43 43 1,000 0,02561345 0,11485543 ! mitochondrion organization GO:0007005 44 43 1,000 0,02561345 0,11457666 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,02561345 0,11429923 ! humoral immune response GO:0006959 44 44 1,000 0,02673578 0,11901942 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,02673578 0,11873262 ! mRNA transport GO:0051028 44 44 1,000 0,02673578 0,11844721 ! amine biosynthetic process GO:0009309 46 45 1,000 0,02787783 0,12321063 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02787783 0,12291587 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02787783 0,12262251 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,02787783 0,12233056 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,02787783 0,12203999 ! rRNA transcription GO:0009303 5 5 0,000 0,02874197 0,12552475 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02874197 0,125228 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02874197 0,12493265 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02874197 0,12463869 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02874197 0,12434611 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02874197 0,1240549 ! reproductive cellular process GO:0048610 5 5 0,000 0,02874197 0,12376505 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02874197 0,12347656 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02874197 0,1231894 ! prostate gland development GO:0030850 5 5 0,000 0,02874197 0,12290358 ! water transport GO:0006833 5 5 0,000 0,02874197 0,12261908 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02874197 0,1223359 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02874197 0,12205402 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02874197 0,12177343 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02874197 0,12149413 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02874197 0,12121612 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02874197 0,12093937 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02874197 0,12066388 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02874197 0,12038964 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02874197 0,12011665 ! filopodium assembly GO:0046847 7 5 0,000 0,02874197 0,11984489 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02874197 0,11957436 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02874197 0,11930505 ! GTP metabolic process GO:0046039 5 5 0,000 0,02874197 0,11903695 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02874197 0,11877005 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02874197 0,11850435 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02874197 0,11823983 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02874197 0,11797649 ! social behavior GO:0035176 5 5 0,000 0,02874197 0,11771432 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02874197 0,11745331 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02874197 0,11719346 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02874197 0,11693475 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02874197 0,11667719 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02874197 0,11642075 ! response to lipid GO:0033993 5 5 0,000 0,02874197 0,11616544 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02874197 0,11591125 ! hippocampus development GO:0021766 6 5 0,000 0,02874197 0,11565817 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02874197 0,11540619 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02874197 0,11515531 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02874197 0,11490552 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02874197 0,1146568 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02874197 0,11440916 ! heart looping GO:0001947 5 5 0,000 0,02874197 0,11416259 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02874197 0,11391708 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02874197 0,11367262 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02874197 0,11342921 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02874197 0,11318684 ! pH reduction GO:0045851 5 5 0,000 0,02874197 0,11294551 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02874197 0,1127052 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02874197 0,11246591 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02874197 0,11222763 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02874197 0,11199037 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02874197 0,1117541 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02874197 0,11151883 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02874197 0,11128454 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02874197 0,11105124 ! adrenal gland development GO:0030325 5 5 0,000 0,02874197 0,11081892 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02874197 0,11058756 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02874197 0,11035717 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02874197 0,11012774 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02874197 0,10989926 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02874197 0,10967172 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02874197 0,10944513 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02874197 0,10921947 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02874197 0,10899474 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02874197 0,10877093 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02874197 0,10854804 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02874197 0,10832606 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02874197 0,10810499 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02874197 0,10788481 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02874197 0,10766553 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02874197 0,10744715 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02874197 0,10722964 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02874197 0,10701302 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02874197 0,10679726 ! response to ATP GO:0033198 5 5 0,000 0,02874197 0,10658238 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02874197 0,10636836 ! regulation of appetite GO:0032098 5 5 0,000 0,02874197 0,1061552 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02874197 0,10594289 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02874197 0,10573142 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02874197 0,1055208 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02874197 0,10531102 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02874197 0,10510207 ! receptor clustering GO:0043113 5 5 0,000 0,02874197 0,10489395 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02874197 0,10468665 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02874197 0,10448016 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02874197 0,10427449 ! retinol metabolic process GO:0042572 5 5 0,000 0,02874197 0,10406963 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02874197 0,10386557 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02874197 0,10366231 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02874197 0,10345985 ! parturition GO:0007567 5 5 0,000 0,02874197 0,10325817 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02874197 0,10305728 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02874197 0,10285717 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02874197 0,10265783 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02874197 0,10245927 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02874197 0,10226147 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02874197 0,10206444 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02874197 0,10186816 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02874197 0,10167263 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02874197 0,10147786 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02874197 0,10128383 ! interaction with symbiont GO:0051702 5 5 0,000 0,02874197 0,10109054 ! cellular extravasation GO:0045123 5 5 0,000 0,02874197 0,10089799 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02874197 0,10070616 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02874197 0,10051507 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02874197 0,1003247 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02874197 0,10013505 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02874197 0,09994612 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02874197 0,0997579 ! response to amine stimulus GO:0014075 5 5 0,000 0,02874197 0,09957038 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02874197 0,09938357 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02874197 0,09919746 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02874197 0,09901204 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02874197 0,09882732 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02874197 0,09864328 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02874197 0,09845993 ! decidualization GO:0046697 5 5 0,000 0,02874197 0,09827726 ! hair follicle maturation GO:0048820 5 5 0,000 0,02874197 0,09809526 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02874197 0,09791394 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02874197 0,09773329 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02874197 0,0975533 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02874197 0,09737398 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02874197 0,09719531 ! postreplication repair GO:0006301 5 5 0,000 0,02874197 0,09701729 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02874197 0,09683993 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,02874197 0,09666322 ! DNA methylation GO:0006306 5 5 0,000 0,02874197 0,09648715 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02874197 0,09631171 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02874197 0,09613692 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02874197 0,09596276 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02874197 0,09578923 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02874197 0,09561632 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02874197 0,09544404 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02874197 0,09527238 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02874197 0,09510133 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02874197 0,0949309 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02874197 0,09476108 ! sterol catabolic process GO:0016127 5 5 0,000 0,02874197 0,09459186 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02874197 0,09442325 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02874197 0,09425524 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02874197 0,09408782 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02874197 0,093921 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02874197 0,09375477 ! zymogen activation GO:0031638 5 5 0,000 0,02874197 0,09358912 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02874197 0,09342406 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02874197 0,09325958 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02874197 0,09309568 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02874197 0,09293236 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02874197 0,0927696 ! nucleosome positioning GO:0016584 5 5 0,000 0,02874197 0,09260742 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02874197 0,0924458 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02874197 0,09228474 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02874197 0,09212425 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02874197 0,09196431 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02874197 0,09180493 ! NADPH regeneration GO:0006740 5 5 0,000 0,02874197 0,09164609 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02874197 0,09148781 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02874197 0,09133007 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02874197 0,09117288 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02874197 0,09101622 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02874197 0,09086011 ! sarcomere organization GO:0045214 5 5 0,000 0,02874197 0,09070453 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02874197 0,09054947 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02874197 0,09039495 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02874197 0,09024096 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02874197 0,09008749 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02874197 0,08993454 ! male genitalia development GO:0030539 5 5 0,000 0,02874197 0,08978211 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02874197 0,08963019 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02874197 0,08947879 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02874197 0,0893279 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02874197 0,08917751 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02874197 0,08902763 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02874197 0,08887826 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02874197 0,08872938 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02874197 0,08858101 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02874197 0,08843313 ! ATP catabolic process GO:0006200 5 5 0,000 0,02874197 0,08828574 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02874197 0,08813884 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02874197 0,08799243 ! blastocyst formation GO:0001825 5 5 0,000 0,02874197 0,08784651 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02874197 0,08770106 ! embryonic gut development GO:0048566 5 5 0,000 0,02874197 0,0875561 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02874197 0,08741162 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02874197 0,08726762 ! activation of innate immune response GO:0002218 5 5 0,000 0,02874197 0,08712408 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,02874197 0,08698102 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02874197 0,08683843 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02874197 0,08669631 ! muscle adaptation GO:0043500 5 5 0,000 0,02874197 0,08655465 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02874197 0,08641345 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02874197 0,08627271 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02874197 0,08613243 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02874197 0,0859926 ! defense response to fungus GO:0050832 5 5 0,000 0,02874197 0,08585323 ! lysogeny GO:0030069 5 5 0,000 0,02874197 0,08571431 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02874197 0,08557584 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02874197 0,08543781 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02874197 0,08530023 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02874197 0,08516309 ! mitochondrion localization GO:0051646 5 5 0,000 0,02874197 0,08502639 ! nucleus localization GO:0051647 5 5 0,000 0,02874197 0,08489013 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02874197 0,08475431 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,02903934 0,0854944 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,02903934 0,08535805 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,02903934 0,08522213 ! sex differentiation GO:0007548 47 47 1,000 0,03022006 0,08854621 ! rhythmic process GO:0048511 47 47 1,000 0,03022006 0,08840566 ! regulation of catabolic process GO:0009894 48 47 1,000 0,03022006 0,08826555 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,03141973 0,09162432 ! DNA recombination GO:0006310 48 48 1,000 0,03141973 0,09147957 ! leukocyte differentiation GO:0002521 50 49 1,000 0,03263812 0,09487707 ! regulation of ligase activity GO:0051340 50 49 1,000 0,03263812 0,09472765 ! RNA transport GO:0050658 50 50 1,000 0,03387498 0,09816286 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 1,000 0,03387498 0,09800876 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03387498 0,09785514 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03439292 0,09919586 ! axon extension GO:0048675 7 6 0,000 0,03439292 0,09904087 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03439292 0,09888636 ! tRNA modification GO:0006400 6 6 0,000 0,03439292 0,09873233 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03439292 0,09857878 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03439292 0,09842571 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03439292 0,09827311 ! virus-host interaction GO:0019048 6 6 0,000 0,03439292 0,09812098 ! regulation of S phase GO:0033261 6 6 0,000 0,03439292 0,09796933 ! myotube differentiation GO:0014902 6 6 0,000 0,03439292 0,09781814 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03439292 0,09766742 ! bone remodeling GO:0046849 6 6 0,000 0,03439292 0,09751716 ! N-glycan processing GO:0006491 6 6 0,000 0,03439292 0,09736736 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03439292 0,09721803 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03439292 0,09706915 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03439292 0,09692073 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03439292 0,09677275 ! RNA methylation GO:0001510 6 6 0,000 0,03439292 0,09662524 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03439292 0,09647816 ! succinate metabolic process GO:0006105 7 6 0,000 0,03439292 0,09633154 ! artery development GO:0060840 6 6 0,000 0,03439292 0,09618536 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03439292 0,09603963 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03439292 0,09589433 ! androgen metabolic process GO:0008209 6 6 0,000 0,03439292 0,09574948 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03439292 0,09560506 ! limbic system development GO:0021761 7 6 0,000 0,03439292 0,09546108 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03439292 0,09531753 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03439292 0,09517441 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03439292 0,09503172 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03439292 0,09488945 ! pathogenesis GO:0009405 6 6 0,000 0,03439292 0,09474761 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03439292 0,0946062 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03439292 0,09446521 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03439292 0,09432463 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03439292 0,09418448 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03439292 0,09404474 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03439292 0,09390541 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03439292 0,0937665 ! arginine metabolic process GO:0006525 6 6 0,000 0,03439292 0,093628 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03439292 0,0934899 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03439292 0,09335222 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03439292 0,09321493 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03439292 0,09307805 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03439292 0,09294158 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03439292 0,0928055 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,03439292 0,09266982 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03439292 0,09253453 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03439292 0,09239964 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03439292 0,09226514 ! regulation of heart rate GO:0002027 6 6 0,000 0,03439292 0,09213104 ! lipid digestion GO:0044241 6 6 0,000 0,03439292 0,09199732 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03439292 0,09186399 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03439292 0,09173105 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03439292 0,09159849 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03439292 0,09146631 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03439292 0,09133452 ! ruffle organization GO:0031529 6 6 0,000 0,03439292 0,0912031 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03439292 0,09107206 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03439292 0,0909414 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03439292 0,09081111 ! L-amino acid transport GO:0015807 6 6 0,000 0,03439292 0,09068119 ! bone mineralization GO:0030282 6 6 0,000 0,03439292 0,09055165 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03439292 0,09042247 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03439292 0,09029367 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03439292 0,09016523 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03439292 0,09003715 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03439292 0,08990944 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03439292 0,08978209 ! regulation of organ growth GO:0046620 6 6 0,000 0,03439292 0,0896551 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03439292 0,08952847 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03439292 0,08940219 ! response to dsRNA GO:0043331 6 6 0,000 0,03439292 0,08927627 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03439292 0,08915071 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03439292 0,0890255 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03439292 0,08890064 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03439292 0,08877613 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03439292 0,08865196 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03439292 0,08852815 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03439292 0,08840468 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03439292 0,08828155 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03439292 0,08815877 ! erythrocyte development GO:0048821 6 6 0,000 0,03439292 0,08803633 ! renal water homeostasis GO:0003091 6 6 0,000 0,03439292 0,08791422 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03439292 0,08779246 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03439292 0,08767103 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03439292 0,08754994 ! ribosome assembly GO:0042255 6 6 0,000 0,03439292 0,08742918 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03439292 0,08730875 ! diencephalon development GO:0021536 6 6 0,000 0,03439292 0,08718866 ! fucose catabolic process GO:0019317 6 6 0,000 0,03439292 0,08706889 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03439292 0,08694946 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03439292 0,08683035 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03439292 0,08671157 ! regulation of cell division GO:0051302 6 6 0,000 0,03439292 0,08659311 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03439292 0,08647497 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03439292 0,08635716 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03439292 0,08623967 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03439292 0,08612249 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03439292 0,08600564 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03439292 0,0858891 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03439292 0,08577287 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03439292 0,08565697 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03439292 0,08554137 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03439292 0,08542608 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03439292 0,08531111 ! lymph node development GO:0048535 6 6 0,000 0,03439292 0,08519644 ! organic cation transport GO:0015695 6 6 0,000 0,03439292 0,08508209 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03439292 0,08496804 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03439292 0,08485429 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03439292 0,08474085 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03439292 0,08462771 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03439292 0,08451487 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03439292 0,08440234 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03439292 0,0842901 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03439292 0,08417816 ! alditol metabolic process GO:0019400 6 6 0,000 0,03439292 0,08406652 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03439292 0,08395517 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03439292 0,08384412 ! maternal placenta development GO:0001893 6 6 0,000 0,03439292 0,08373336 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03439292 0,08362289 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03439292 0,08351272 ! RNA localization GO:0006403 52 52 1,000 0,0364031 0,08827752 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,03769389 0,09128756 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03769389 0,09116776 ! regulation of protein transport GO:0051223 53 53 1,000 0,03769389 0,09104828 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,03900218 0,09408509 ! response to virus GO:0009615 54 54 1,000 0,03900218 0,09396211 ! respiratory burst GO:0045730 7 7 0,000 0,04001182 0,09626864 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04001182 0,09614313 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04001182 0,09601794 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04001182 0,09589308 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04001182 0,09576854 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04001182 0,09564433 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04001182 0,09552044 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04001182 0,09539687 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04001182 0,09527361 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04001182 0,09515068 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04001182 0,09502806 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04001182 0,09490576 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04001182 0,09478378 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04001182 0,0946621 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04001182 0,09454074 ! axis specification GO:0009798 7 7 0,000 0,04001182 0,09441969 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04001182 0,09429895 ! visual behavior GO:0007632 7 7 0,000 0,04001182 0,09417852 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04001182 0,09405839 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04001182 0,09393857 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04001182 0,09381906 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04001182 0,09369984 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04001182 0,09358094 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04001182 0,09346233 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04001182 0,09334402 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04001182 0,09322601 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04001182 0,09310831 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04001182 0,09299089 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04001182 0,09287378 ! protein targeting to ER GO:0045047 8 7 0,000 0,04001182 0,09275695 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04001182 0,09264042 ! endoderm development GO:0007492 7 7 0,000 0,04001182 0,09252419 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04001182 0,09240824 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04001182 0,09229259 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04001182 0,09217722 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04001182 0,09206214 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04001182 0,09194735 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04001182 0,09183285 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04001182 0,09171863 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04001182 0,09160469 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04001182 0,09149104 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04001182 0,09137767 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04001182 0,09126458 ! response to X-ray GO:0010165 7 7 0,000 0,04001182 0,09115176 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04001182 0,09103923 ! UV protection GO:0009650 7 7 0,000 0,04001182 0,09092698 ! DNA integration GO:0015074 7 7 0,000 0,04001182 0,090815 ! myofibril assembly GO:0030239 7 7 0,000 0,04001182 0,09070329 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04001182 0,09059186 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04001182 0,09048071 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04001182 0,09036983 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04001182 0,09025921 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04001182 0,09014887 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04001182 0,0900388 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04001182 0,089929 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04001182 0,08981946 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04001182 0,08971019 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04001182 0,08960119 ! axon cargo transport GO:0008088 7 7 0,000 0,04001182 0,08949245 ! eating behavior GO:0042755 7 7 0,000 0,04001182 0,08938397 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04001182 0,08927576 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04001182 0,08916781 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04001182 0,08906012 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04001182 0,08895269 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04001182 0,08884552 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04001182 0,0887386 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04001182 0,08863194 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04001182 0,08852554 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04001182 0,0884194 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04001182 0,08831351 ! platelet activation GO:0030168 8 7 0,000 0,04001182 0,08820787 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04001182 0,08810248 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04001182 0,08799735 ! natural killer cell activation GO:0030101 7 7 0,000 0,04001182 0,08789246 ! NADP metabolic process GO:0006739 7 7 0,000 0,04001182 0,08778783 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04001182 0,08768345 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04001182 0,08757931 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04001182 0,08747542 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04001182 0,08737177 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04001182 0,08726838 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04001182 0,08716522 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04001182 0,08706231 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04001182 0,08695964 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04001182 0,08685722 ! cell-cell recognition GO:0009988 8 7 0,000 0,04001182 0,08675503 ! hormone catabolic process GO:0042447 7 7 0,000 0,04001182 0,08665309 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04001182 0,08655138 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04001182 0,08644992 ! oxygen transport GO:0015671 7 7 0,000 0,04001182 0,08634869 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04001182 0,08624769 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04001182 0,08614694 ! cell killing GO:0001906 7 7 0,000 0,04001182 0,08604641 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04001182 0,08594613 ! adult feeding behavior GO:0008343 7 7 0,000 0,04001182 0,08584607 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04001182 0,08574625 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04001182 0,08564666 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04001182 0,08554731 ! response to cold GO:0009409 7 7 0,000 0,04001182 0,08544818 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,04032773 0,08602316 ! reproductive developmental process GO:0003006 56 56 1,000 0,04167031 0,08878426 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04559883 0,09704231 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04559883 0,09693038 ! positive regulation of translation GO:0045727 8 8 0,000 0,04559883 0,09681871 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04559883 0,09670729 ! superoxide anion generation GO:0042554 8 8 0,000 0,04559883 0,09659614 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04559883 0,09648523 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04559883 0,09637459 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04559883 0,09626419 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04559883 0,09615405 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04559883 0,09604416 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04559883 0,09593452 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04559883 0,09582513 ! zinc ion transport GO:0006829 8 8 0,000 0,04559883 0,09571599 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04559883 0,0956071 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04559883 0,09549845 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04559883 0,09539006 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04559883 0,0952819 ! lipid localization GO:0010876 8 8 0,000 0,04559883 0,095174 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04559883 0,09506633 ! response to cAMP GO:0051591 8 8 0,000 0,04559883 0,09495891 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04559883 0,09485174 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04559883 0,0947448 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04559883 0,09463811 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04559883 0,09453165 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04559883 0,09442544 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04559883 0,09431946 ! sensory perception of taste GO:0050909 8 8 0,000 0,04559883 0,09421372 ! organelle fusion GO:0048284 8 8 0,000 0,04559883 0,09410822 ! pancreas development GO:0031016 8 8 0,000 0,04559883 0,09400295 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04559883 0,09389792 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04559883 0,09379312 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04559883 0,09368856 ! sperm motility GO:0030317 8 8 0,000 0,04559883 0,09358423 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04559883 0,09348013 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04559883 0,09337627 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04559883 0,09327263 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04559883 0,09316922 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04559883 0,09306605 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04559883 0,0929631 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04559883 0,09286037 ! Golgi organization GO:0007030 8 8 0,000 0,04559883 0,09275788 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04559883 0,09265561 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04559883 0,09255357 ! fructose metabolic process GO:0006000 8 8 0,000 0,04559883 0,09245175 ! mannose metabolic process GO:0006013 9 8 0,000 0,04559883 0,09235015 ! NAD metabolic process GO:0019674 8 8 0,000 0,04559883 0,09224878 ! sex determination GO:0007530 8 8 0,000 0,04559883 0,09214763 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04559883 0,0920467 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,04559883 0,09194599 ! response to fungus GO:0009620 8 8 0,000 0,04559883 0,09184551 ! stem cell differentiation GO:0048863 8 8 0,000 0,04559883 0,09174524 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04559883 0,09164519 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04559883 0,09154536 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04559883 0,09144574 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04559883 0,09134635 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04559883 0,09124717 ! vasoconstriction GO:0042310 8 8 0,000 0,04559883 0,0911482 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04559883 0,09104945 ! muscle cell development GO:0055001 8 8 0,000 0,04559883 0,09095091 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04559883 0,09085258 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04559883 0,09075447 ! sensory perception of pain GO:0019233 8 8 0,000 0,04559883 0,09065657 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04559883 0,09055888 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04559883 0,0904614 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04559883 0,09036413 ! chromatin silencing GO:0006342 8 8 0,000 0,04559883 0,09026707 ! tissue regeneration GO:0042246 8 8 0,000 0,04559883 0,09017021 ! salivary gland development GO:0007431 8 8 0,000 0,04559883 0,09007357 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04559883 0,08997713 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04559883 0,0898809 ! water homeostasis GO:0030104 8 8 0,000 0,04559883 0,08978487 ! cofactor transport GO:0051181 8 8 0,000 0,04559883 0,08968905 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04559883 0,08959343 ! acid secretion GO:0046717 8 8 0,000 0,04559883 0,08949802 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04559883 0,08940281 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04559883 0,0893078 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04559883 0,08921299 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04559883 0,08911839 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04559883 0,08902398 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04559883 0,08892978 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04559883 0,08883577 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04559883 0,08874196 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04559883 0,08864835 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04559883 0,08855494 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04559883 0,08846173 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04559883 0,08836871 ! peptide hormone secretion GO:0030072 8 8 0,000 0,04559883 0,08827588 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04559883 0,08818325 ! actin filament polymerization GO:0030041 9 8 0,000 0,04559883 0,08809082 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04559883 0,08799857 ! peptide hormone processing GO:0016486 8 8 0,000 0,04559883 0,08790653 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04559883 0,08781467 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04559883 0,08772301 ! dephosphorylation GO:0016311 60 59 1,000 0,04579794 0,08801418 ! immune effector process GO:0002252 59 59 1,000 0,04579794 0,08792249 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,04863064 0,09326354 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,04863064 0,09316659 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,0500706 0,09582567 ! lactation GO:0007595 10 9 0,000 0,05115413 0,09779778 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05115413 0,09769644 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05115413 0,0975953 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,05115413 0,09749438 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05115413 0,09739366 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05115413 0,09729315 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,05115413 0,09719285 ! viral genome replication GO:0019079 9 9 0,000 0,05115413 0,09709275 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05115413 0,09699286 ! copper ion transport GO:0006825 9 9 0,000 0,05115413 0,09689318 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05115413 0,0967937 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05115413 0,09669442 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05115413 0,09659535 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05115413 0,09649648 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05115413 0,09639782 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05115413 0,09629935 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05115413 0,09620109 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05115413 0,09610302 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05115413 0,09600516 ! phospholipid efflux GO:0033700 9 9 0,000 0,05115413 0,09590749 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05115413 0,09581002 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05115413 0,09571276 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05115413 0,09561568 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05115413 0,09551881 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05115413 0,09542213 ! methionine metabolic process GO:0006555 9 9 0,000 0,05115413 0,09532565 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05115413 0,09522936 ! cerebral cortex development GO:0021987 9 9 0,000 0,05115413 0,09513326 ! response to osmotic stress GO:0006970 9 9 0,000 0,05115413 0,09503736 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05115413 0,09494166 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05115413 0,09484614 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05115413 0,09475082 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05115413 0,09465569 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05115413 0,09456075 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05115413 0,094466 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05115413 0,09437144 ! L-glutamate transport GO:0015813 9 9 0,000 0,05115413 0,09427706 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05115413 0,09418288 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05115413 0,09408889 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05115413 0,09399508 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05115413 0,09390146 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05115413 0,09380802 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05115413 0,09371478 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05115413 0,09362171 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,05115413 0,09352883 ! DNA replication initiation GO:0006270 9 9 0,000 0,05115413 0,09343614 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05115413 0,09334363 GO:0006692|prostanoid metabolic process, ! regulation of cellular pH GO:0030641 9 9 0,000 0,05115413 0,0932513 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05115413 0,09315915 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05115413 0,09306719 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05115413 0,09297541 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05115413 0,09288381 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05115413 0,09279239 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05115413 0,09270114 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05115413 0,09261008 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05115413 0,0925192 ! collagen catabolic process GO:0030574 9 9 0,000 0,05115413 0,09242849 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05115413 0,09233797 ! purine base metabolic process GO:0006144 9 9 0,000 0,05115413 0,09224762 ! gas transport GO:0015669 9 9 0,000 0,05115413 0,09215744 ! cholesterol efflux GO:0033344 9 9 0,000 0,05115413 0,09206745 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05115413 0,09197762 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05115413 0,09188798 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05115413 0,0917985 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05115413 0,09170921 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05115413 0,09162008 ! actin filament-based movement GO:0030048 9 9 0,000 0,05115413 0,09153113 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05115413 0,09144235 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,05152602 0,09201788 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,05299666 0,09455261 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,05598278 0,09978362 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0566779 0,100925 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0566779 0,10082758 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0566779 0,10073035 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0566779 0,10063331 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,0566779 0,10053645 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0566779 0,10043978 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0566779 0,1003433 ! neuron maturation GO:0042551 10 10 0,000 0,0566779 0,100247 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0566779 0,10015089 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0566779 0,10005496 GO:0045767|regulation of anti-apoptosis, ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0566779 0,09995921 ! hormone secretion GO:0046879 10 10 0,000 0,0566779 0,09986365 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0566779 0,09976827 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0566779 0,09967307 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,0566779 0,09957805 ! inositol metabolic process GO:0006020 10 10 0,000 0,0566779 0,09948321 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0566779 0,09938856 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0566779 0,09929408 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0566779 0,09919979 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0566779 0,09910567 ! glial cell development GO:0021782 10 10 0,000 0,0566779 0,09901173 ! phototransduction GO:0007602 11 10 0,000 0,0566779 0,09891797 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,0566779 0,09882438 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0566779 0,09873098 ! fat cell differentiation GO:0045444 10 10 0,000 0,0566779 0,09863775 ! myoblast differentiation GO:0045445 10 10 0,000 0,0566779 0,09854469 ! centrosome cycle GO:0007098 10 10 0,000 0,0566779 0,09845181 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0566779 0,09835911 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0566779 0,09826658 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0566779 0,09817422 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0566779 0,09808204 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0566779 0,09799003 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0566779 0,0978982 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0566779 0,09780653 ! plasma membrane organization GO:0007009 10 10 0,000 0,0566779 0,09771504 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,0566779 0,09762371 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,0566779 0,09753256 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0566779 0,09744158 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0566779 0,09735077 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0566779 0,09726013 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0566779 0,09716965 ! exocrine system development GO:0035272 10 10 0,000 0,0566779 0,09707934 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0566779 0,09698921 ! embryo implantation GO:0007566 11 10 0,000 0,0566779 0,09689923 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0566779 0,09680943 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0566779 0,09671979 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0566779 0,09663032 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0566779 0,09654101 ! protein export from nucleus GO:0006611 10 10 0,000 0,0566779 0,09645187 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0566779 0,09636289 ! cytolysis GO:0019835 10 10 0,000 0,0566779 0,09627408 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0566779 0,09618543 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0566779 0,09609694 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0566779 0,09600862 ! histone deacetylation GO:0016575 10 10 0,000 0,0566779 0,09592045 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0566779 0,09583245 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0566779 0,09574461 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0566779 0,09565694 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0566779 0,09556942 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0566779 0,09548206 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0566779 0,09539486 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,0566779 0,09530782 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0566779 0,09522094 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0566779 0,09513422 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0566779 0,09504766 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0566779 0,09496125 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,0566779 0,094875 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0566779 0,09478891 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,0566779 0,09470297 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0566779 0,09461719 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,0566779 0,09453156 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0566779 0,09444609 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0566779 0,09436077 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0566779 0,09427561 ! protein stabilization GO:0050821 10 10 0,000 0,0566779 0,0941906 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,05749783 0,09546711 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,05902725 0,09791829 ! regulation of cell size GO:0008361 68 68 1,000 0,05902725 0,09783023 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,06057084 0,10029835 ! positive regulation of transport GO:0051050 71 70 1,000 0,06212839 0,10278512 ! growth GO:0040007 70 70 1,000 0,06212839 0,10269294 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,06212839 0,10260092 GO:0016053|organic acid biosynthetic process, ! protein secretion GO:0009306 11 11 0,000 0,06217032 0,10257824 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06217032 0,10248649 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06217032 0,1023949 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06217032 0,10230348 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06217032 0,10221222 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06217032 0,10212112 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06217032 0,10203018 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06217032 0,10193941 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06217032 0,10184879 ! skin development GO:0043588 11 11 0,000 0,06217032 0,10175834 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06217032 0,10166805 ! signal complex assembly GO:0007172 11 11 0,000 0,06217032 0,10157792 ! microtubule-based transport GO:0010970 11 11 0,000 0,06217032 0,10148795 ! peroxisomal transport GO:0043574 11 11 0,000 0,06217032 0,10139814 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06217032 0,10130848 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06217032 0,10121899 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06217032 0,10112965 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,06217032 0,10104047 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06217032 0,10095145 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06217032 0,10086258 ! spinal cord development GO:0021510 11 11 0,000 0,06217032 0,10077387 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06217032 0,10068532 ! cellular response to starvation GO:0009267 11 11 0,000 0,06217032 0,10059692 ! digestive system process GO:0022600 11 11 0,000 0,06217032 0,10050868 ! fucose metabolic process GO:0006004 11 11 0,000 0,06217032 0,10042059 ! membrane budding GO:0006900 11 11 0,000 0,06217032 0,10033266 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,06217032 0,10024488 ! monoamine transport GO:0015844 11 11 0,000 0,06217032 0,10015725 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06217032 0,10006978 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06217032 0,09998246 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,06217032 0,09989529 ! body fluid secretion GO:0007589 11 11 0,000 0,06217032 0,09980827 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06217032 0,0997214 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06217032 0,09963469 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06217032 0,09954813 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,06217032 0,09946171 ! membrane depolarization GO:0051899 11 11 0,000 0,06217032 0,09937545 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06217032 0,09928934 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06217032 0,09920337 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06217032 0,09911756 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06217032 0,09903189 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,06217032 0,09894637 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,06217032 0,098861 ! muscle maintenance GO:0046716 12 11 0,000 0,06217032 0,09877577 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06217032 0,09869069 ! steroid catabolic process GO:0006706 11 11 0,000 0,06217032 0,09860576 ! endocrine process GO:0050886 11 11 0,000 0,06217032 0,09852097 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06217032 0,09843633 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06217032 0,09835184 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06217032 0,09826749 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06217032 0,09818329 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,0636997 0,10051246 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0636997 0,10042648 ! regulation of cell activation GO:0050865 71 71 1,000 0,0636997 0,10034064 ! secretion by cell GO:0032940 75 72 1,000 0,06528456 0,10274932 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,06528456 0,10266165 ! sensory organ development GO:0007423 72 72 1,000 0,06528456 0,10257413 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,06763155 0,10617116 ! translational initiation GO:0006413 12 12 0,000 0,06763155 0,1060808 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06763155 0,1059906 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06763155 0,10590054 ! initiation of viral infection GO:0019059 12 12 0,000 0,06763155 0,10581065 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06763155 0,1057209 ! iron ion transport GO:0006826 13 12 0,000 0,06763155 0,10563131 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06763155 0,10554186 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06763155 0,10545257 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06763155 0,10536343 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06763155 0,10527444 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06763155 0,1051856 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06763155 0,10509691 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06763155 0,10500837 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06763155 0,10491998 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06763155 0,10483174 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06763155 0,10474365 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06763155 0,1046557 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06763155 0,1045679 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06763155 0,10448025 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06763155 0,10439275 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06763155 0,10430539 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06763155 0,10421818 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06763155 0,10413111 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06763155 0,10404419 ! acute-phase response GO:0006953 12 12 0,000 0,06763155 0,10395741 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06763155 0,10387078 ! vacuolar transport GO:0007034 12 12 0,000 0,06763155 0,1037843 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06763155 0,10369795 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06763155 0,10361175 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06763155 0,1035257 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06763155 0,10343978 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06763155 0,10335401 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06763155 0,10326838 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06763155 0,1031829 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06763155 0,10309755 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06763155 0,10301235 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06763155 0,10292728 ! pallium development GO:0021543 13 12 0,000 0,06763155 0,10284236 ! cell fate determination GO:0001709 12 12 0,000 0,06763155 0,10275758 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,06763155 0,10267293 ! G1 phase GO:0051318 13 12 0,000 0,06763155 0,10258843 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06763155 0,10250406 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06763155 0,10241984 ! detection of light stimulus GO:0009583 13 12 0,000 0,06763155 0,10233575 ! synaptogenesis GO:0007416 12 12 0,000 0,06763155 0,1022518 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06763155 0,10216798 ! hormone transport GO:0009914 12 12 0,000 0,06763155 0,10208431 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06763155 0,10200077 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06763155 0,10191737 ! spermatid differentiation GO:0048515 13 12 0,000 0,06763155 0,1018341 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06763155 0,10175097 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06763155 0,10166798 ! neural tube closure GO:0001843 13 12 0,000 0,06763155 0,10158512 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,06763155 0,10150239 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06763155 0,1014198 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,06763155 0,10133735 ! response to oxidative stress GO:0006979 76 75 1,000 0,07011846 0,10497833 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,07175553 0,10734209 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,07175553 0,10725503 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,07306176 0,10911899 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07306176 0,10903063 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07306176 0,10894242 ! phenol metabolic process GO:0018958 13 13 0,000 0,07306176 0,10885435 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,07306176 0,10876642 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,07306176 0,10867864 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07306176 0,10859099 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07306176 0,10850349 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07306176 0,10841613 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07306176 0,10832891 ! keratinization GO:0031424 13 13 0,000 0,07306176 0,10824183 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07306176 0,10815489 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07306176 0,10806808 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07306176 0,10798142 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,07306176 0,1078949 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07306176 0,10780851 ! autophagy GO:0006914 13 13 0,000 0,07306176 0,10772227 ! receptor metabolic process GO:0043112 14 13 0,000 0,07306176 0,10763616 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,07306176 0,10755019 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07306176 0,10746435 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07306176 0,10737865 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07306176 0,10729309 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07306176 0,10720767 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07306176 0,10712238 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07306176 0,10703723 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07306176 0,10695221 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07306176 0,10686733 ! vasodilation GO:0042311 14 13 0,000 0,07306176 0,10678258 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07306176 0,10669797 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,07306176 0,10661349 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07306176 0,10652914 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,07306176 0,10644493 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07306176 0,10636085 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07306176 0,1062769 ! immunoglobulin production GO:0002377 13 13 0,000 0,07306176 0,10619309 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07306176 0,1061094 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,07306176 0,10602585 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07306176 0,10594243 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07306176 0,10585914 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07306176 0,10577599 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07306176 0,10569296 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07306176 0,10561006 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07306176 0,1055273 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07306176 0,10544466 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07306176 0,10536215 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07306176 0,10527978 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07306176 0,10519753 ! blastocyst development GO:0001824 13 13 0,000 0,07306176 0,1051154 ! telomere organization GO:0032200 13 13 0,000 0,07306176 0,10503341 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07306176 0,10495154 ! regulation of amine transport GO:0051952 13 13 0,000 0,07306176 0,10486981 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07306176 0,1047882 ! protein tetramerization GO:0051262 13 13 0,000 0,07306176 0,10470671 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,07340517 0,10511712 ! regulation of protein modification process GO:0031399 79 78 1,000 0,07506718 0,10741368 ! metal ion homeostasis GO:0055065 78 78 1,000 0,07506718 0,10733034 ! neuron fate commitment GO:0048663 14 14 0,000 0,07846114 0,11209604 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,07846114 0,11200921 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,07846114 0,11192251 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,07846114 0,11183595 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,07846114 0,11174953 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,07846114 0,11166323 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,07846114 0,11157707 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,07846114 0,11149105 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,07846114 0,11140515 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,07846114 0,11131939 ! vesicle docking GO:0048278 14 14 0,000 0,07846114 0,11123376 ! superoxide metabolic process GO:0006801 15 14 0,000 0,07846114 0,11114826 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,07846114 0,11106289 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,07846114 0,11097766 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,07846114 0,11089255 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,07846114 0,11080758 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,07846114 0,11072273 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 14 14 0,000 0,07846114 0,11063802 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,07846114 0,11055343 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,07846114 0,11046897 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,07846114 0,11038465 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,07846114 0,11030045 ! primary neural tube formation GO:0014020 15 14 0,000 0,07846114 0,11021638 ! peptide cross-linking GO:0018149 14 14 0,000 0,07846114 0,11013243 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,07846114 0,11004862 ! base-excision repair GO:0006284 14 14 0,000 0,07846114 0,10996493 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,07846114 0,10988137 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,07846114 0,10979794 ! formation of primary germ layer GO:0001704 14 14 0,000 0,07846114 0,10971463 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,07846114 0,10963145 ! collagen fibril organization GO:0030199 14 14 0,000 0,07846114 0,1095484 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,07846114 0,10946547 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,07846114 0,10938267 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,07846114 0,10929999 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,07846114 0,10921744 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,07846114 0,10913501 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,07846114 0,1090527 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,07846114 0,10897052 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,07846114 0,10888847 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,07846114 0,10880654 ! lymphocyte activation GO:0046649 82 81 1,000 0,08012552 0,11103108 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,08382985 0,11607695 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,08382985 0,1159898 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,08382985 0,11590279 ! positive regulation of ossification GO:0045778 15 15 0,000 0,08382985 0,1158159 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,08382985 0,11572915 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,08382985 0,11564253 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,08382985 0,11555603 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,08382985 0,11546967 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,08382985 0,11538343 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,08382985 0,11529733 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,08382985 0,11521135 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,08382985 0,1151255 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,08382985 0,11503977 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,08382985 0,11495418 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,08382985 0,11486871 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,08382985 0,11478337 ! heme metabolic process GO:0042168 15 15 0,000 0,08382985 0,11469816 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,08382985 0,11461307 ! chromosome condensation GO:0030261 15 15 0,000 0,08382985 0,11452811 ! response to starvation GO:0042594 15 15 0,000 0,08382985 0,11444327 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,08382985 0,11435856 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,08382985 0,11427398 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,08382985 0,11418952 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,08382985 0,11410518 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,08382985 0,11402097 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,08382985 0,11393689 ! phospholipid transport GO:0015914 15 15 0,000 0,08382985 0,11385292 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,08382985 0,11376908 ! glutathione metabolic process GO:0006749 16 15 0,000 0,08382985 0,11368537 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,08382985 0,11360178 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,08382985 0,11351831 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,08382985 0,11343496 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,08382985 0,11335174 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,08382985 0,11326863 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,08382985 0,11318565 ! protein homooligomerization GO:0051260 15 15 0,000 0,08382985 0,11310279 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,08382985 0,11302006 ! regulation of cellular localization GO:0060341 86 85 1,000 0,08703176 0,11725113 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,08703176 0,11716548 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,08703176 0,11707996 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,08703176 0,11699456 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,08916806 0,11977896 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,08916806 0,11969172 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,08916806 0,11960461 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,08916806 0,11951763 ! learning GO:0007612 16 16 0,000 0,08916806 0,11943077 ! circadian rhythm GO:0007623 16 16 0,000 0,08916806 0,11934403 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,08916806 0,11925743 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,08916806 0,11917095 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,08916806 0,11908459 ! vacuole organization GO:0007033 16 16 0,000 0,08916806 0,11899836 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,08916806 0,11891225 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,08916806 0,11882627 ! vesicle targeting GO:0006903 17 16 0,000 0,08916806 0,11874042 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,08916806 0,11865468 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,08916806 0,11856907 ! iron ion homeostasis GO:0055072 16 16 0,000 0,08916806 0,11848359 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,08916806 0,11839822 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,08916806 0,11831298 ! pentose metabolic process GO:0019321 16 16 0,000 0,08916806 0,11822787 ! fatty acid transport GO:0015908 16 16 0,000 0,08916806 0,11814287 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,08916806 0,118058 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,08916806 0,11797325 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,08916806 0,11788862 ! cofactor catabolic process GO:0051187 16 16 0,000 0,08916806 0,11780411 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,08916806 0,11771972 ! polyol metabolic process GO:0019751 16 16 0,000 0,08916806 0,11763546 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,08916806 0,11755131 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,08916806 0,11746729 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,08916806 0,11738338 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,08916806 0,1172996 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,08916806 0,11721593 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,08916806 0,11713238 ! regulation of coagulation GO:0050818 17 16 0,000 0,08916806 0,11704896 ! male gamete generation GO:0048232 90 88 1,000 0,09232642 0,1211086 GO:0007283|spermatogenesis, ! chemotaxis GO:0006935 90 89 1,000 0,09411225 0,12336336 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,09411225 0,12327568 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,09447594 0,12366417 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,09447594 0,12357641 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09447594 0,12348876 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09447594 0,12340124 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,09447594 0,12331385 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,09447594 0,12322658 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,09447594 0,12313943 ! sensory perception of smell GO:0007608 17 17 0,000 0,09447594 0,12305241 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,09447594 0,12296551 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09447594 0,12287873 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09447594 0,12279207 ! neural crest cell development GO:0014032 19 17 0,000 0,09447594 0,12270554 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09447594 0,12261912 GO:0002764|immune response-regulating signal transduction, ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09447594 0,12253283 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,09447594 0,12244666 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09447594 0,12236062 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09447594 0,12227469 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09447594 0,12218888 ! embryonic organ development GO:0048568 17 17 0,000 0,09447594 0,12210319 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09447594 0,12201763 ! liver development GO:0001889 17 17 0,000 0,09447594 0,12193218 ! gene silencing GO:0016458 17 17 0,000 0,09447594 0,12184685 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,09771432 0,12593531 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,09953021 0,128186 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,09953021 0,12809649 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09975365 0,12829448 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09975365 0,12820501 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09975365 0,12811567 ! membrane docking GO:0022406 18 18 0,000 0,09975365 0,12802645 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09975365 0,12793736 ! response to calcium ion GO:0051592 18 18 0,000 0,09975365 0,12784839 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09975365 0,12775955 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09975365 0,12767082 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,09975365 0,12758222 ! striated muscle contraction GO:0006941 18 18 0,000 0,09975365 0,12749375 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09975365 0,1274054 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09975365 0,12731716 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09975365 0,12722906 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09975365 0,12714107 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09975365 0,1270532 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,09975365 0,12696546 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09975365 0,12687784 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,09975365 0,12679033 ! BMP signaling pathway GO:0030509 18 18 0,000 0,09975365 0,12670295 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09975365 0,12661569 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,09975365 0,12652855 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09975365 0,12644153 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10500137 0,13300174 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10500137 0,13291039 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,10500137 0,13281917 ! glial cell differentiation GO:0010001 19 19 0,000 0,10500137 0,13272808 ! regulation of pH GO:0006885 19 19 0,000 0,10500137 0,1326371 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10500137 0,13254626 ! feeding behavior GO:0007631 19 19 0,000 0,10500137 0,13245553 ! peroxisome organization GO:0007031 19 19 0,000 0,10500137 0,13236493 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10500137 0,13227446 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10500137 0,13218411 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,10500137 0,13209388 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10500137 0,13200377 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10500137 0,13191379 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10500137 0,13182393 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10500137 0,1317342 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10500137 0,13164458 ! eye morphogenesis GO:0048592 19 19 0,000 0,10500137 0,13155509 ! placenta development GO:0001890 19 19 0,000 0,10500137 0,13146572 ! vesicle localization GO:0051648 20 19 0,000 0,10500137 0,13137647 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,11021926 0,13781147 ! negative regulation of binding GO:0051100 21 20 0,000 0,11021926 0,13771804 ! organic ether metabolic process GO:0018904 20 20 0,000 0,11021926 0,13762473 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,11021926 0,13753155 ! neural tube development GO:0021915 21 20 0,000 0,11021926 0,1374385 ! nucleus organization GO:0006997 20 20 0,000 0,11021926 0,13734557 ! phagocytosis GO:0006909 21 20 0,000 0,11021926 0,13725277 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,11021926 0,1371601 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11021926 0,13706755 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11021926 0,13697512 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11021926 0,13688282 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,11021926 0,13679064 ! lipid oxidation GO:0034440 20 20 0,000 0,11021926 0,13669859 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,11021926 0,13660666 ! RNA modification GO:0009451 20 20 0,000 0,11021926 0,13651486 ! single fertilization GO:0007338 21 20 0,000 0,11021926 0,13642317 ! regulation of B cell activation GO:0050864 20 20 0,000 0,11021926 0,13633161 ! regulation of system process GO:0044057 98 98 1,000 0,11062297 0,13673919 ! response to other organism GO:0051707 101 100 1,000 0,11439187 0,14130309 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,11540749 0,14246216 ! mRNA catabolic process GO:0006402 21 21 0,000 0,11540749 0,1423668 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,11540749 0,14227158 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11540749 0,14217647 ! Notch signaling pathway GO:0007219 22 21 0,000 0,11540749 0,1420815 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11540749 0,14198665 ! ear morphogenesis GO:0042471 21 21 0,000 0,11540749 0,14189193 ! organic anion transport GO:0015711 21 21 0,000 0,11540749 0,14179734 ! cholesterol transport GO:0030301 21 21 0,000 0,11540749 0,14170287 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11540749 0,14160853 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11540749 0,14151431 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,11540749 0,14142022 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11540749 0,14132625 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11540749 0,14123241 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,11540749 0,14113869 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11540749 0,1410451 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,11540749 0,14095163 ! RNA export from nucleus GO:0006405 22 22 0,000 0,12056622 0,14715466 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,12056622 0,14705727 ! sister chromatid segregation GO:0000819 22 22 0,000 0,12056622 0,14696001 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,12056622 0,14686288 ! regulation of ion transport GO:0043269 22 22 0,000 0,12056622 0,14676588 ! odontogenesis GO:0042476 22 22 0,000 0,12056622 0,146669 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,12056622 0,14657225 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,12056622 0,14647563 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,12056622 0,14637914 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,12056622 0,14628278 ! cell chemotaxis GO:0060326 23 22 0,000 0,12056622 0,14618654 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,12056622 0,14609043 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,12056622 0,14599444 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,12056622 0,14589858 ! biopolymer methylation GO:0043414 22 22 0,000 0,12056622 0,14580285 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,12056622 0,14570724 ! detection of external stimulus GO:0009581 23 22 0,000 0,12056622 0,14561175 ! neuron migration GO:0001764 22 22 0,000 0,12056622 0,1455164 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,12056622 0,14542116 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,12056622 0,14532605 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,12056622 0,14523107 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,12056622 0,14513621 ! aerobic respiration GO:0009060 22 22 0,000 0,12056622 0,14504147 ! cytokine production GO:0001816 22 22 0,000 0,12056622 0,14494686 ! cytokinesis GO:0000910 23 22 0,000 0,12056622 0,14485237 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,12056622 0,144758 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,12569561 0,15081836 ! viral infectious cycle GO:0019058 23 23 0,000 0,12569561 0,15072024 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,12569561 0,15062224 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,12569561 0,15052437 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12569561 0,15042662 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,12569561 0,15032901 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12569561 0,15023152 ! endocrine system development GO:0035270 23 23 0,000 0,12569561 0,15013416 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,12569561 0,15003692 ! lipid homeostasis GO:0055088 23 23 0,000 0,12569561 0,14993981 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,12569561 0,14984282 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12569561 0,14974596 ! cell projection assembly GO:0030031 25 23 0,000 0,12569561 0,14964923 ! gliogenesis GO:0042063 24 24 0,000 0,13079582 0,15562085 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,13079582 0,15552045 ! glucose homeostasis GO:0042593 24 24 0,000 0,13079582 0,15542018 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,13079582 0,15532004 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,13079582 0,15522002 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,13079582 0,15512014 ! fertilization GO:0009566 25 24 0,000 0,13079582 0,15502038 ! maintenance of protein location GO:0045185 25 24 0,000 0,13079582 0,15492076 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,13079582 0,15482126 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,13079582 0,15472189 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,13586702 0,16061766 ! negative regulation of secretion GO:0051048 26 25 0,000 0,13586702 0,1605147 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,13586702 0,16041187 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,13586702 0,16030917 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,13586702 0,16020661 ! endosome transport GO:0016197 25 25 0,000 0,13586702 0,16010417 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,13586702 0,16000187 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,13586702 0,1598997 ! excretion GO:0007588 25 25 0,000 0,13586702 0,15979765 ! gastrulation GO:0007369 25 25 0,000 0,13586702 0,15969574 ! heart morphogenesis GO:0003007 25 25 0,000 0,13586702 0,15959396 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,13586702 0,15949231 ! regulation of endocytosis GO:0030100 25 25 0,000 0,13586702 0,15939079 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,13586702 0,15928939 ! positive regulation of defense response GO:0031349 26 26 0,000 0,14090938 0,16509598 ! glycolysis GO:0006096 26 26 0,000 0,14090938 0,16499109 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,14090938 0,16488634 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,14090938 0,16478171 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,14090938 0,16467722 ! cellular defense response GO:0006968 26 26 0,000 0,14090938 0,16457286 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,14090938 0,16446864 ! double-strand break repair GO:0006302 27 26 0,000 0,14090938 0,16436454 ! regulation of protein secretion GO:0050708 26 26 0,000 0,14090938 0,16426058 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,14090938 0,16415675 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,14090938 0,16405305 ! chloride transport GO:0006821 27 27 0,000 0,14592304 0,16978293 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14592304 0,16967581 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14592304 0,16956882 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,14592304 0,16946197 ! peptide metabolic process GO:0006518 29 27 0,000 0,14592304 0,16935526 ! activation of caspase activity GO:0006919 27 27 0,000 0,14592304 0,16924868 ! inner ear development GO:0048839 27 27 0,000 0,14592304 0,16914224 ! defense response to bacterium GO:0042742 27 27 0,000 0,14592304 0,16903592 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14592304 0,16892974 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14592304 0,1688237 ! cell growth GO:0016049 27 27 0,000 0,14592304 0,16871779 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,15090816 0,17437225 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,15090816 0,174263 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,15090816 0,17415388 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,15090816 0,1740449 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,15090816 0,17393605 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,15090816 0,17382734 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,15090816 0,17371877 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15586492 0,17931276 ! viral reproductive process GO:0022415 29 29 0,000 0,15586492 0,1792009 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,15586492 0,17908918 ! leukocyte migration GO:0050900 30 29 0,000 0,15586492 0,1789776 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15586492 0,17886615 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15586492 0,17875485 ! tRNA processing GO:0008033 29 29 0,000 0,15586492 0,17864368 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,15586492 0,17853265 ! adult behavior GO:0030534 30 29 0,000 0,15586492 0,17842176 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15586492 0,17831101 ! transition metal ion transport GO:0000041 31 30 0,000 0,16079345 0,18383519 ! RNA catabolic process GO:0006401 30 30 0,000 0,16079345 0,18372122 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,16079345 0,18360739 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,16079345 0,1834937 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,16079345 0,18338016 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,16079345 0,18326675 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,16079345 0,18315348 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,16079345 0,18304035 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,16079345 0,18292737 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,16079345 0,18281452 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,16079345 0,18270181 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,16079345 0,18258924 ! establishment of organelle localization GO:0051656 31 30 0,000 0,16079345 0,18247681 ! membrane fusion GO:0006944 31 31 0,000 0,16569393 0,18792241 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,16569393 0,18780683 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16569393 0,1876914 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16569393 0,18757611 ! digestion GO:0007586 31 31 0,000 0,16569393 0,18746096 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16569393 0,18734596 ! regulation of DNA replication GO:0006275 32 31 0,000 0,16569393 0,18723109 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16569393 0,18711637 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16569393 0,18700178 ! camera-type eye development GO:0043010 31 31 0,000 0,16569393 0,18688734 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16569393 0,18677303 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,16569393 0,18665887 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,16569393 0,18654484 ! cell redox homeostasis GO:0045454 32 32 0,000 0,1705665 0,19191335 ! glucose catabolic process GO:0006007 32 32 0,000 0,1705665 0,19179625 ! lipid modification GO:0030258 32 32 0,000 0,1705665 0,1916793 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,1705665 0,1915625 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,1705665 0,19144583 ! cell maturation GO:0048469 32 32 0,000 0,1705665 0,19132931 ! nuclear export GO:0051168 32 32 0,000 0,1705665 0,19121293 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,1705665 0,19109669 ! maintenance of location GO:0051235 33 32 0,000 0,1705665 0,1909806 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,17541132 0,19628601 ! amino acid transport GO:0006865 33 33 0,000 0,17541132 0,19616691 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,17541132 0,19604795 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,17541132 0,19592913 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,17541132 0,19581046 ! regulation of actin filament length GO:0030832 34 34 0,000 0,18022855 0,20106611 ! muscle cell differentiation GO:0042692 35 34 0,000 0,18022855 0,20094447 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,18022855 0,20082298 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,18022855 0,20070164 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,18022855 0,20058044 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,18022855 0,20045939 ! viral reproduction GO:0016032 34 34 0,000 0,18022855 0,20033849 ! detection of stimulus GO:0051606 36 34 0,000 0,18022855 0,20021773 ! acute inflammatory response GO:0002526 35 35 0,000 0,18501833 0,20541493 ! regulation of cellular component size GO:0032535 35 35 0,000 0,18501833 0,20529126 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,18501833 0,20516774 ! mesoderm development GO:0007498 35 35 0,000 0,18501833 0,20504437 ! inorganic anion transport GO:0015698 35 35 0,000 0,18501833 0,20492115 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18501833 0,20479807 ! hydrogen transport GO:0006818 36 36 0,000 0,18978083 0,20994361 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,18978083 0,20981767 ! regulation of mitosis GO:0007088 37 36 0,000 0,18978083 0,20969188 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,18978083 0,20956624 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,18978083 0,20944075 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,18978083 0,20931542 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,18978083 0,20919023 ! activation of immune response GO:0002253 36 36 0,000 0,18978083 0,20906519 ! coagulation GO:0050817 39 36 0,000 0,18978083 0,2089403 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,19451618 0,21402586 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,19451618 0,21389816 ! eye development GO:0001654 37 37 0,000 0,19451618 0,21377061 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19451618 0,21364322 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19451618 0,21351597 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,19451618 0,21338888 ! positive regulation of secretion GO:0051047 39 38 0,000 0,19922455 0,21842406 ! neurotransmitter transport GO:0006836 40 38 0,000 0,19922455 0,2182942 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,19922455 0,21816449 ! exocytosis GO:0006887 40 38 0,000 0,19922455 0,21803494 ! chromosome segregation GO:0007059 38 38 0,000 0,19922455 0,21790554 ! hexose catabolic process GO:0019320 38 38 0,000 0,19922455 0,2177763 ! RNA elongation GO:0006354 38 38 0,000 0,19922455 0,21764721 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,19922455 0,21751827 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,20390607 0,22249787 ! hemostasis GO:0007599 42 39 0,000 0,20390607 0,22236621 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,20390607 0,22223471 ! activation of MAPK activity GO:0000187 39 39 0,000 0,20390607 0,22210337 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,20390607 0,22197218 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,20390607 0,22184114 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,20390607 0,22171026 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,20390607 0,22157954 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,20390607 0,22144897 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,20390607 0,22131855 ! developmental maturation GO:0021700 39 39 0,000 0,20390607 0,22118828 ! limb development GO:0060173 39 39 0,000 0,20390607 0,22105817 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,20390607 0,22092822 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,20856091 0,22583887 ! DNA catabolic process GO:0006308 41 40 0,000 0,20856091 0,22570626 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,20856091 0,22557381 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,20856091 0,2254415 ! organelle localization GO:0051640 41 40 0,000 0,20856091 0,22530936 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,21318921 0,23017441 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,21318921 0,23003965 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,21318921 0,22990504 ! regulation of caspase activity GO:0043281 41 41 0,000 0,21318921 0,2297706 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,21318921 0,22963631 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,21318921 0,22950217 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,21318921 0,2293682 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,21318921 0,22923438 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,21779112 0,23404608 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,21779112 0,23390969 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,21779112 0,23377346 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,21779112 0,23363739 ! protein ubiquitination GO:0016567 43 42 0,000 0,21779112 0,23350147 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,21779112 0,23336572 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,21779112 0,23323012 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,21779112 0,23309468 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,22236678 0,23785373 ! alcohol catabolic process GO:0046164 43 43 0,000 0,22236678 0,23771576 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,22236678 0,23757795 ! protein import into nucleus GO:0006606 44 44 0,000 0,22691634 0,24229827 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,22691634 0,24215797 ! vitamin metabolic process GO:0006766 44 44 0,000 0,22691634 0,24201783 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,22691634 0,24187785 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,23143994 0,24655711 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,23143994 0,24641468 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,23143994 0,24627241 ! nuclear import GO:0051170 45 45 0,000 0,23143994 0,2461303 ! protein processing GO:0016485 45 45 0,000 0,23143994 0,24598835 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,23593773 0,25062434 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,23593773 0,25047997 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,23593773 0,25033577 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,23593773 0,25019173 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,24040985 0,25478744 ! regulation of blood pressure GO:0008217 48 47 0,000 0,24040985 0,25464101 ! amine transport GO:0015837 47 47 0,000 0,24040985 0,25449475 ! calcium ion transport GO:0006816 48 48 0,000 0,24485645 0,25905306 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,24485645 0,25890444 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,24485645 0,25875599 ! protein localization in nucleus GO:0034504 48 48 0,000 0,24485645 0,2586077 ! cell cycle arrest GO:0007050 49 49 0,000 0,24927767 0,26312643 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,24927767 0,26297581 ! divalent metal ion transport GO:0070838 49 49 0,000 0,24927767 0,26282537 ! response to bacterium GO:0009617 50 49 0,000 0,24927767 0,26267509 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,24927767 0,26252499 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,24927767 0,26237506 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,25367364 0,26684961 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,25367364 0,26669739 ! negative regulation of transport GO:0051051 51 50 0,000 0,25367364 0,26654533 ! chromatin assembly GO:0031497 50 50 0,000 0,25367364 0,26639346 GO:0006334|nucleosome assembly, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,25367364 0,26624175 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,25367364 0,26609022 ! transcription initiation GO:0006352 50 50 0,000 0,25367364 0,26593886 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,25804451 0,27036727 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,25804451 0,27021366 ! positive regulation of immune response GO:0050778 51 51 0,000 0,25804451 0,27006021 ! rRNA metabolic process GO:0016072 51 51 0,000 0,25804451 0,26990694 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,25804451 0,26975385 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,25804451 0,26960093 ! protein maturation GO:0051604 51 51 0,000 0,25804451 0,26944818 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,26239042 0,273831 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,26239042 0,27367603 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,26239042 0,27352124 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,26239042 0,27336662 ! sodium ion transport GO:0006814 53 53 0,000 0,26671151 0,27771147 ! tRNA metabolic process GO:0006399 53 53 0,000 0,26671151 0,27755466 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,26671151 0,27739803 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,26671151 0,27724157 ! hormone metabolic process GO:0042445 55 54 0,000 0,27100791 0,2815488 ! sulfur metabolic process GO:0006790 55 54 0,000 0,27100791 0,28139019 ! nucleosome organization GO:0034728 55 55 0,000 0,27527977 0,28566476 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,27527977 0,285504 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,27527977 0,28534342 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,27527977 0,28518303 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,27952721 0,28942059 ! ATP metabolic process GO:0046034 57 57 0,000 0,28375038 0,29362827 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,28375038 0,2934635 ! innate immune response GO:0045087 58 58 0,000 0,28794941 0,29763924 ! carboxylic acid transport GO:0046942 59 59 0,000 0,29212444 0,3017855 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,29212444 0,30161643 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,29212444 0,30144756 ! protein localization in organelle GO:0033365 59 59 0,000 0,29212444 0,30127887 ! potassium ion transport GO:0006813 60 60 0,000 0,29627559 0,30538921 ! protein polymerization GO:0051258 65 60 0,000 0,29627559 0,30521851 ! cellular respiration GO:0045333 62 61 0,000 0,30040301 0,30929762 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,30040301 0,30912492 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,30040301 0,30895242 ! lipid transport GO:0006869 62 62 0,000 0,30450682 0,31299836 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,30450682 0,31282389 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,30450682 0,31264962 ! protein import GO:0017038 62 62 0,000 0,30450682 0,31247554 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,30450682 0,31230165 ! regulation of secretion GO:0051046 65 63 0,000 0,30858715 0,31631041 ! glucose metabolic process GO:0006006 63 63 0,000 0,30858715 0,31613459 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,30858715 0,31595896 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,30858715 0,31578352 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,31264414 0,31975758 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,31264414 0,31958023 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,31264414 0,31940308 ! anion transport GO:0006820 65 65 0,000 0,31667792 0,32334483 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,31667792 0,32316579 ! regulation of hormone levels GO:0010817 66 65 0,000 0,31667792 0,32298695 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,32068862 0,32689664 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,32068862 0,32671593 ! DNA packaging GO:0006323 66 66 0,000 0,32068862 0,32653543 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,32467636 0,33041332 ! muscle contraction GO:0006936 67 67 0,000 0,32467636 0,33023097 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,32864127 0,33407935 ! sensory perception of sound GO:0007605 71 69 0,000 0,33258348 0,33790042 GO:0050954|sensory perception of mechanical stimulus, ! translational elongation GO:0006414 71 71 0,000 0,34040031 0,34565167 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,34040031 0,34546133 ! ribosome biogenesis GO:0042254 71 71 0,000 0,34040031 0,3452712 ! muscle system process GO:0003012 72 72 0,000 0,34427518 0,34900944 ! regulation of cytokine production GO:0001817 72 72 0,000 0,34427518 0,34881757 ! electron transport chain GO:0022900 75 74 0,000 0,35195845 0,35640628 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,35195845 0,35621056 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,3557671 0,3598676 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,3557671 0,35967019 ! microtubule-based movement GO:0007018 82 78 0,000 0,36706257 0,37088613 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,36706257 0,37068291 ! regulation of immune response GO:0050776 78 78 0,000 0,36706257 0,37047991 ! nuclear transport GO:0051169 79 79 0,000 0,37078463 0,37403179 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,37448536 0,37755827 ! lipid catabolic process GO:0016042 82 81 0,000 0,37816485 0,3810595 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,38546065 0,38819889 ! ncRNA processing GO:0034470 83 83 0,000 0,38546065 0,38798688 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,38907718 0,39141334 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,3962481 0,39840985 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,3962481 0,39819261 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,40333693 0,40509535 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,41034458 0,41190908 ! visual perception GO:0007601 93 92 0,000 0,41727197 0,41863486 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,41727197 0,41840709 ! regulation of response to stress GO:0080134 97 94 0,000 0,42411998 0,42504248 ! cofactor metabolic process GO:0051186 95 94 0,000 0,42411998 0,42481148 ! endocytosis GO:0006897 99 98 0,000 0,43758142 0,43805679 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,43758142 0,43781898 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,44419659 0,44419659