pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6312-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! elastic fiber assembly GO:0048251 15 9 6,000 1,44E-15 3,464E-12 ! collagen metabolic process GO:0032963 45 31 6,000 9,658E-11 1,162E-07 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 6,000 1,953E-10 1,566E-07 ! multicellular organismal metabolic process GO:0044236 57 40 6,000 6,613E-10 3,978E-07 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 5,000 1,316E-08 6,332E-06 ! extracellular matrix organization GO:0030198 133 66 6,000 2,498E-08 1,002E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 5,535E-08 1,902E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 9,959E-08 2,995E-05 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 4,000 1,502E-07 4,015E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 2,151E-07 5,175E-05 GO:0050927|positive regulation of positive chemotaxis, ! L-serine biosynthetic process GO:0006564 6 5 2,000 9,765E-07 2,136E-04 ! cell-substrate junction assembly GO:0007044 54 18 3,000 1,301E-06 2,609E-04 ! neural nucleus development GO:0048857 14 6 2,000 1,946E-06 3,602E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,125E-06 3,653E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 2,517E-06 4,038E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 3,000 3,066E-06 4,61E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 3,394E-06 4,804E-04 ! response to protein stimulus GO:0051789 149 91 5,000 4,366E-06 5,835E-04 ! regulation of behavior GO:0050795 43 24 3,000 4,421E-06 5,599E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 4,421E-06 5,319E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 5,244E-06 6,009E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 5,413E-06 5,919E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 5,606E-06 5,864E-04 ! aging GO:0007568 103 55 4,000 5,83E-06 5,845E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 6,176E-06 5,943E-04 GO:0045936|negative regulation of phosphate metabolic process, ! interphase GO:0051325 213 98 5,000 6,713E-06 6,212E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 6,965E-06 6,207E-04 ! cell junction assembly GO:0034329 78 30 3,000 1,116E-05 9,588E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 1,152E-05 9,557E-04 ! L-serine metabolic process GO:0006563 18 10 2,000 1,152E-05 9,238E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,152E-05 8,94E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 1,548E-05 1,164E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 1,579E-05 1,151E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 1,579E-05 1,117E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 1,579E-05 1,085E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of kinase activity GO:0033673 131 68 4,000 1,664E-05 1,112E-03 ! focal adhesion formation GO:0048041 35 12 2,000 2,098E-05 1,364E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 2,201E-05 1,394E-03 ! cell junction organization GO:0034330 86 36 3,000 2,347E-05 1,448E-03 ! cell-matrix adhesion GO:0007160 163 75 4,000 2,685E-05 1,615E-03 ! negative regulation of mitotic cell cycle GO:0045930 33 13 2,000 2,717E-05 1,595E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 2,717E-05 1,557E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 3,447E-05 1,929E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 3,447E-05 1,885E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 3,447E-05 1,843E-03 ! cell-substrate adhesion GO:0031589 171 81 4,000 3,898E-05 2,039E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 4,294E-05 2,198E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 4,294E-05 2,152E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 4,795E-05 2,354E-03 ! response to unfolded protein GO:0006986 131 85 4,000 4,916E-05 2,366E-03 ! JAK-STAT cascade GO:0007259 71 44 3,000 5,255E-05 2,479E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 5,267E-05 2,437E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 6,272E-05 2,847E-03 ! pigmentation GO:0043473 100 46 3,000 6,272E-05 2,795E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 6,374E-05 2,788E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 6,374E-05 2,738E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 7,622E-05 3,217E-03 ! chromatin remodeling GO:0006338 109 51 3,000 9,434E-05 3,913E-03 ! cartilage development GO:0051216 90 52 3,000 1,018E-04 4,153E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,058E-04 4,241E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,058E-04 4,172E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,058E-04 4,104E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,058E-04 4,039E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 29 20 2,000 1,058E-04 3,976E-03 ! response to UV GO:0009411 104 53 3,000 1,097E-04 4,062E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 1,23E-04 4,483E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,23E-04 4,416E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,23E-04 4,351E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,419E-04 4,948E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,459E-04 5,016E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 1,626E-04 5,511E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 1,669E-04 5,578E-03 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 1,669E-04 5,502E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 1,9E-04 6,179E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 2,024E-04 6,494E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,126E-04 6,73E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 2,126E-04 6,643E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,126E-04 6,558E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,126E-04 6,475E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,126E-04 6,394E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,126E-04 6,315E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,126E-04 6,238E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,126E-04 6,163E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,126E-04 6,089E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,126E-04 6,018E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,126E-04 5,948E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 2,126E-04 5,879E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,126E-04 5,812E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,126E-04 5,747E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 2,289E-04 6,119E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,363E-04 6,249E-03 ! actin filament organization GO:0007015 148 66 3,000 2,578E-04 6,742E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,65E-04 6,855E-03 ! protein amino acid acylation GO:0043543 55 27 2,000 2,65E-04 6,782E-03 ! lung development GO:0030324 144 67 3,000 2,732E-04 6,918E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 2,732E-04 6,846E-03 ! dendrite development GO:0016358 59 28 2,000 2,958E-04 7,336E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 2,958E-04 7,261E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 3,059E-04 7,434E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 3,179E-04 7,649E-03 ! protein lipoylation GO:0009249 10 6 1,000 3,179E-04 7,573E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 3,179E-04 7,499E-03 ! negative regulation of axon extension GO:0030517 21 6 1,000 3,179E-04 7,426E-03 ! respiratory tube development GO:0030323 150 70 3,000 3,233E-04 7,479E-03 ! respiratory system development GO:0060541 153 72 3,000 3,601E-04 8,252E-03 ! response to heat GO:0009408 50 30 2,000 3,641E-04 8,264E-03 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 4,017E-04 9,033E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 4,418E-04 9,841E-03 ! hindbrain development GO:0030902 61 32 2,000 4,418E-04 9,751E-03 ! negative regulation of cellular catabolic process GO:0031330 12 7 1,000 4,437E-04 9,705E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,437E-04 9,618E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,437E-04 9,532E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,437E-04 9,448E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,437E-04 9,365E-03 ! protein-cofactor linkage GO:0018065 13 7 1,000 4,437E-04 9,284E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 4,437E-04 9,203E-03 ! organ growth GO:0035265 15 7 1,000 4,437E-04 9,125E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 4,437E-04 9,047E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,437E-04 8,971E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 4,437E-04 8,897E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,437E-04 8,823E-03 ! axonal fasciculation GO:0007413 18 7 1,000 4,437E-04 8,751E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 4,437E-04 8,68E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 4,437E-04 8,61E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 4,843E-04 9,322E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 4,843E-04 9,248E-03 GO:0060326|cell chemotaxis, ! positive regulation of phosphorylation GO:0042327 129 79 3,000 5,129E-04 9,717E-03 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 5,294E-04 9,95E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 5,639E-04 0,0105176 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 3,000 5,639E-04 0,01043669 ! regulation of muscle development GO:0048634 70 35 2,000 5,77E-04 0,01059778 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,898E-04 0,01075098 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 5,898E-04 0,01067015 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,898E-04 0,01059052 ! T-helper 1 type immune response GO:0042088 12 8 1,000 5,898E-04 0,01051207 ! pigment granule organization GO:0048753 16 8 1,000 5,898E-04 0,01043477 ! ER overload response GO:0006983 12 8 1,000 5,898E-04 0,01035861 ! regulation of pigmentation during development GO:0048070 24 8 1,000 5,898E-04 0,01028355 ! melanin metabolic process GO:0006582 15 8 1,000 5,898E-04 0,01020956 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 5,898E-04 0,01013664 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,898E-04 0,01006475 ! response to UV-B GO:0010224 16 8 1,000 5,898E-04 9,994E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,898E-04 9,924E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 5,898E-04 9,855E-03 ! response to oxygen levels GO:0070482 176 83 3,000 6,184E-04 0,01026115 ! DNA integrity checkpoint GO:0031570 75 36 2,000 6,273E-04 0,01033825 ! meiosis I GO:0007127 65 37 2,000 6,804E-04 0,01113605 ! regulation of protein stability GO:0031647 73 37 2,000 6,804E-04 0,01106081 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 6,804E-04 0,01098657 ! tube morphogenesis GO:0035239 176 86 3,000 7,07E-04 0,01134001 ! microtubule bundle formation GO:0001578 21 9 1,000 7,56E-04 0,01204657 ! middle ear morphogenesis GO:0042474 14 9 1,000 7,56E-04 0,01196732 ! T cell selection GO:0045058 23 9 1,000 7,56E-04 0,0118891 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 7,56E-04 0,0118119 ! behavioral fear response GO:0001662 22 9 1,000 7,56E-04 0,0117357 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 7,56E-04 0,01166047 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 7,56E-04 0,0115862 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 7,56E-04 0,01151287 ! induction of an organ GO:0001759 14 9 1,000 7,56E-04 0,01144046 ! regulation of telomere maintenance GO:0032204 14 9 1,000 7,56E-04 0,01136895 ! ossification GO:0001503 188 90 3,000 8,386E-04 0,01253194 ! bone development GO:0060348 189 91 3,000 8,74E-04 0,01298067 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 9,422E-04 0,01390713 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 9,422E-04 0,01382233 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 9,422E-04 0,01373856 ! lung alveolus development GO:0048286 26 10 1,000 9,422E-04 0,0136558 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 9,422E-04 0,01357402 ! B cell proliferation GO:0042100 18 10 1,000 9,422E-04 0,01349323 ! regulation of bone resorption GO:0045124 25 10 1,000 9,422E-04 0,01341338 ! alpha-beta T cell activation GO:0046631 23 10 1,000 9,422E-04 0,01333448 ! negative regulation of axonogenesis GO:0050771 32 10 1,000 9,422E-04 0,0132565 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 9,422E-04 0,01317943 ! oocyte development GO:0048599 17 10 1,000 9,422E-04 0,01310325 ! response to nicotine GO:0035094 20 10 1,000 9,422E-04 0,01302794 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 9,422E-04 0,0129535 ! localization within membrane GO:0051668 20 10 1,000 9,422E-04 0,0128799 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 9,48E-04 0,01288631 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,059E-03 0,0143126 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,148E-03 0,01543111 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,148E-03 0,01534539 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,148E-03 0,0152606 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,148E-03 0,01517675 ! blood vessel remodeling GO:0001974 29 11 1,000 1,148E-03 0,01509382 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,148E-03 0,01501179 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,148E-03 0,01493065 ! negative regulation of ossification GO:0030279 26 11 1,000 1,148E-03 0,01485037 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,148E-03 0,01477096 ! oocyte differentiation GO:0009994 18 11 1,000 1,148E-03 0,01469239 ! thymus development GO:0048538 27 11 1,000 1,148E-03 0,01461465 ! developmental induction GO:0031128 19 11 1,000 1,148E-03 0,01453773 GO:0045168|cell-cell signaling involved in cell fate specification, ! leukocyte migration GO:0050900 68 45 2,000 1,209E-03 0,01523327 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,209E-03 0,01515393 ! negative regulation of cell migration GO:0030336 115 46 2,000 1,289E-03 0,01607264 ! response to insulin stimulus GO:0032868 95 46 2,000 1,289E-03 0,01598979 ! positive regulation of defense response GO:0031349 76 47 2,000 1,373E-03 0,01693495 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 1,373E-03 0,01685975 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 1,373E-03 0,01677416 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,373E-03 0,01668944 ! cartilage condensation GO:0001502 20 12 1,000 1,373E-03 0,01660558 ! protein complex disassembly GO:0043241 27 12 1,000 1,373E-03 0,01652255 GO:0043624|cellular protein complex disassembly, ! mitotic spindle organization GO:0007052 21 12 1,000 1,373E-03 0,01644035 ! fear response GO:0042596 26 12 1,000 1,373E-03 0,01635896 ! cranial nerve development GO:0021545 20 12 1,000 1,373E-03 0,01627837 ! histone acetylation GO:0016573 26 12 1,000 1,373E-03 0,01619858 ! autonomic nervous system development GO:0048483 24 12 1,000 1,373E-03 0,01611956 ! gland morphogenesis GO:0022612 29 12 1,000 1,373E-03 0,01604131 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,373E-03 0,01596382 ! T cell homeostasis GO:0043029 25 12 1,000 1,373E-03 0,01588707 ! spleen development GO:0048536 22 12 1,000 1,373E-03 0,01581105 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,373E-03 0,01573576 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,373E-03 0,01566119 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,373E-03 0,01558731 ! cellular component disassembly GO:0022411 86 48 2,000 1,459E-03 0,0164815 ! regulation of inflammatory response GO:0050727 75 48 2,000 1,459E-03 0,01640448 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,459E-03 0,01632818 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 1,549E-03 0,01725402 ! response to temperature stimulus GO:0009266 76 49 2,000 1,549E-03 0,01717451 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,618E-03 0,01785983 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,618E-03 0,01777828 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,618E-03 0,01769747 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,618E-03 0,01761739 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 1,739E-03 0,01884742 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,739E-03 0,0187629 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,739E-03 0,01867914 ! regulation of angiogenesis GO:0045765 114 52 2,000 1,839E-03 0,01966799 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,839E-03 0,01958096 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,839E-03 0,0194947 ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,882E-03 0,01986196 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 1,882E-03 0,01977523 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 1,882E-03 0,01968925 ! response to gamma radiation GO:0010332 28 14 1,000 1,882E-03 0,01960402 ! regulation of RNA stability GO:0043487 32 14 1,000 1,882E-03 0,01951952 ! regulation of axon extension GO:0030516 37 14 1,000 1,882E-03 0,01943574 ! negative regulation of cell motion GO:0051271 134 55 2,000 2,161E-03 0,0222233 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,165E-03 0,02216736 ! heterophilic cell adhesion GO:0007157 39 15 1,000 2,165E-03 0,02207343 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,165E-03 0,0219803 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,165E-03 0,02188794 ! regulation of bone remodeling GO:0046850 137 57 2,000 2,394E-03 0,02410367 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 2,467E-03 0,02473091 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,467E-03 0,02462829 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,467E-03 0,02452652 GO:0031114|regulation of microtubule depolymerization, ! neuron recognition GO:0008038 35 16 1,000 2,467E-03 0,02442559 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,467E-03 0,02432548 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 1,000 2,467E-03 0,02422619 ! regulation of tissue remodeling GO:0034103 140 58 2,000 2,516E-03 0,02461181 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 2,772E-03 0,02700148 ! regulation of heart contraction GO:0008016 110 60 2,000 2,772E-03 0,02689261 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,772E-03 0,0267846 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 2,772E-03 0,02667747 ! metencephalon development GO:0022037 30 17 1,000 2,787E-03 0,02671857 ! endothelial cell migration GO:0043542 28 17 1,000 2,787E-03 0,02661254 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,787E-03 0,02650735 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,787E-03 0,02640299 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,787E-03 0,02629945 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,787E-03 0,02619672 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,787E-03 0,02609479 ! regulation of protein binding GO:0043393 33 17 1,000 2,787E-03 0,02599364 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,787E-03 0,02589328 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 2,787E-03 0,02579369 ! ear development GO:0043583 103 62 2,000 3,043E-03 0,02805126 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,126E-03 0,0287089 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 3,126E-03 0,02859974 ! memory GO:0007613 31 18 1,000 3,126E-03 0,02849141 ! patterning of blood vessels GO:0001569 39 18 1,000 3,126E-03 0,02838389 ! epidermis morphogenesis GO:0048730 40 18 1,000 3,126E-03 0,02827718 ! response to retinoic acid GO:0032526 26 18 1,000 3,126E-03 0,02817128 ! nerve development GO:0021675 28 18 1,000 3,126E-03 0,02806616 ! lipid phosphorylation GO:0046834 35 19 1,000 3,483E-03 0,03115653 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 3,483E-03 0,03104114 ! forelimb morphogenesis GO:0035136 32 19 1,000 3,483E-03 0,03092659 ! pigmentation during development GO:0048066 41 19 1,000 3,483E-03 0,03081289 ! response to vitamin A GO:0033189 27 19 1,000 3,483E-03 0,03070002 ! actin filament bundle formation GO:0051017 42 19 1,000 3,483E-03 0,03058798 ! neuromuscular junction development GO:0007528 34 19 1,000 3,483E-03 0,03047675 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 3,483E-03 0,03036633 ! cellular pigmentation GO:0033059 36 19 1,000 3,483E-03 0,0302567 ! negative regulation of cell growth GO:0030308 132 67 2,000 3,79E-03 0,03280045 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,859E-03 0,03327622 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,859E-03 0,03315738 ! response to vitamin GO:0033273 31 20 1,000 3,859E-03 0,03303938 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,859E-03 0,03292222 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,859E-03 0,03280589 ! negative regulation of cell size GO:0045792 134 69 2,000 4,117E-03 0,03488014 ! hindlimb morphogenesis GO:0035137 43 21 1,000 4,252E-03 0,03589541 ! ovarian follicle development GO:0001541 35 21 1,000 4,252E-03 0,0357699 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 4,252E-03 0,03564527 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 4,252E-03 0,0355215 ! cell aging GO:0007569 44 21 1,000 4,252E-03 0,03539859 ! oogenesis GO:0048477 36 21 1,000 4,252E-03 0,03527652 ! response to cytokine stimulus GO:0034097 63 21 1,000 4,252E-03 0,0351553 ! gut development GO:0048565 39 21 1,000 4,252E-03 0,0350349 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 4,639E-03 0,0380973 ! regeneration GO:0031099 41 22 1,000 4,663E-03 0,0381601 ! apoptotic nuclear changes GO:0030262 32 22 1,000 4,663E-03 0,03803074 ! ureteric bud development GO:0001657 43 22 1,000 4,663E-03 0,03790226 ! renal system process GO:0003014 41 22 1,000 4,663E-03 0,03777464 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,663E-03 0,03764788 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 4,663E-03 0,03752197 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,663E-03 0,0373969 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 4,663E-03 0,03727265 ! axon guidance GO:0007411 139 73 2,000 4,822E-03 0,03841641 ! meiosis GO:0007126 121 74 2,000 5,009E-03 0,03977331 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,092E-03 0,04029699 ! leukocyte adhesion GO:0007159 50 23 1,000 5,092E-03 0,04016487 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 5,092E-03 0,04003361 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 5,092E-03 0,03990321 ! regulation of viral reproduction GO:0050792 38 23 1,000 5,092E-03 0,03977365 ! negative regulation of catabolic process GO:0009895 50 23 1,000 5,092E-03 0,03964493 ! meiotic cell cycle GO:0051321 122 75 2,000 5,2E-03 0,04035888 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,538E-03 0,04284061 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 5,538E-03 0,0427033 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 5,538E-03 0,04256687 ! multicellular organismal response to stress GO:0033555 49 24 1,000 5,538E-03 0,0424313 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 5,538E-03 0,0422966 ! lymphocyte proliferation GO:0046651 48 24 1,000 5,538E-03 0,04216275 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 5,538E-03 0,04202975 ! leukocyte homeostasis GO:0001776 44 24 1,000 5,538E-03 0,04189758 ! myelination GO:0042552 45 25 1,000 6,001E-03 0,0452605 ! vasculogenesis GO:0001570 46 25 1,000 6,001E-03 0,04511906 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,001E-03 0,0449785 ! negative regulation of cell development GO:0010721 73 25 1,000 6,001E-03 0,04483881 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 6,001E-03 0,04469999 ! neural tube closure GO:0001843 49 25 1,000 6,001E-03 0,04456203 GO:0060606|tube closure, ! regulation of neuron differentiation GO:0045664 167 81 2,000 6,439E-03 0,04766906 ! molting cycle process GO:0022404 50 26 1,000 6,481E-03 0,04783401 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 6,481E-03 0,04768773 ! macromolecular complex disassembly GO:0032984 53 26 1,000 6,481E-03 0,04754234 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 6,481E-03 0,04739783 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 6,481E-03 0,0472542 ! leukocyte proliferation GO:0070661 52 26 1,000 6,481E-03 0,04711144 GO:0032943|mononuclear cell proliferation, ! response to drug GO:0042493 143 82 2,000 6,661E-03 0,04827348 ! response to nutrient GO:0007584 125 82 2,000 6,661E-03 0,04812851 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 6,661E-03 0,04798441 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 6,979E-03 0,05012058 ! mitochondrial membrane organization GO:0007006 57 27 1,000 6,979E-03 0,04997141 ! male gonad development GO:0008584 44 27 1,000 6,979E-03 0,04982313 ! response to toxin GO:0009636 47 27 1,000 6,979E-03 0,04967572 ! primary neural tube formation GO:0014020 51 27 1,000 6,979E-03 0,04952919 ! regulation of chromosome organization GO:0033044 42 27 1,000 6,979E-03 0,04938351 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 6,979E-03 0,04923869 ! negative regulation of transport GO:0051051 153 84 2,000 7,119E-03 0,05008225 ! negative regulation of growth GO:0045926 155 84 2,000 7,119E-03 0,04993623 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 7,493E-03 0,05240472 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 7,493E-03 0,05225282 ! amine biosynthetic process GO:0009309 138 86 2,000 7,595E-03 0,05281307 ! mitochondrion organization GO:0007005 148 86 2,000 7,595E-03 0,05266087 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 8,023E-03 0,0554712 ! response to organic cyclic substance GO:0014070 55 29 1,000 8,023E-03 0,05531225 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 8,023E-03 0,05515422 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 8,023E-03 0,05499708 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 8,023E-03 0,05484084 ! tissue homeostasis GO:0001894 48 29 1,000 8,023E-03 0,05468549 GO:0048871|multicellular organismal homeostasis, ! positive regulation of protein modification process GO:0031401 136 88 2,000 8,089E-03 0,05497957 ! gland development GO:0048732 206 88 2,000 8,089E-03 0,0548247 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 8,343E-03 0,05638822 ! regulation of cell adhesion GO:0030155 212 89 2,000 8,343E-03 0,05623027 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 8,57E-03 0,0575985 ! ensheathment of neurons GO:0007272 57 30 1,000 8,57E-03 0,05743806 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 8,57E-03 0,05727851 ! regulation of B cell activation GO:0050864 50 30 1,000 8,57E-03 0,05711985 ! ovulation cycle process GO:0022602 49 31 1,000 9,134E-03 0,06070634 ! iron ion homeostasis GO:0055072 54 31 1,000 9,134E-03 0,06053911 ! regulation of defense response GO:0031347 149 92 2,000 9,134E-03 0,06037337 ! regulation of membrane potential GO:0042391 164 93 2,000 9,407E-03 0,06200659 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 9,407E-03 0,06183718 ! response to hydrogen peroxide GO:0042542 50 32 1,000 9,713E-03 0,06367816 ! spindle organization GO:0007051 46 32 1,000 9,713E-03 0,06350512 ! metanephros development GO:0001656 74 32 1,000 9,713E-03 0,06333302 ! response to ionizing radiation GO:0010212 65 32 1,000 9,713E-03 0,06316185 ! response to mechanical stimulus GO:0009612 57 32 1,000 9,713E-03 0,0629916 ! regulation of axonogenesis GO:0050770 75 32 1,000 9,713E-03 0,06282227 ! ovulation cycle GO:0042698 51 32 1,000 9,713E-03 0,06265384 ! peripheral nervous system development GO:0007422 64 32 1,000 9,713E-03 0,06248632 ! post-embryonic development GO:0009791 69 33 1,000 0,01030858 0,06613985 ! cell fate specification GO:0001708 52 33 1,000 0,01030858 0,06596394 ! regulation of protein localization GO:0032880 176 97 2,000 0,01054549 0,06730094 ! response to virus GO:0009615 160 98 2,000 0,01084213 0,069011 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01114356 0,07074249 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 2,000 0,0114498 0,07249533 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01154662 0,07291642 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01154662 0,07272554 ! female gonad development GO:0008585 58 35 1,000 0,01154662 0,07253566 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01154662 0,07234676 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01154662 0,07215885 ! neural tube formation GO:0001841 67 35 1,000 0,01154662 0,07197191 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01218893 0,07577921 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01218893 0,07558391 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01218893 0,0753896 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 0,01284656 0,07925337 ! tissue remodeling GO:0048771 76 37 1,000 0,01284656 0,07905068 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01284656 0,07884902 ! pigment metabolic process GO:0042440 80 37 1,000 0,01284656 0,07864839 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,01351935 0,08255728 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01351935 0,08234827 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01351935 0,08214032 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01351935 0,08193342 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01351935 0,08172756 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01351935 0,08152272 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01351935 0,08131892 ! glucan metabolic process GO:0044042 62 38 1,000 0,01351935 0,08111613 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01420717 0,08503095 ! ear morphogenesis GO:0042471 60 39 1,000 0,01420717 0,08481995 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01420717 0,08461 ! segmentation GO:0035282 67 39 1,000 0,01420717 0,08440109 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01420717 0,0841932 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01490984 0,08814023 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01562722 0,09215465 ! T cell differentiation GO:0030217 81 41 1,000 0,01562722 0,09192933 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01562722 0,09170511 ! female gamete generation GO:0007292 61 41 1,000 0,01562722 0,09148199 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,01562722 0,09125994 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01635917 0,09530304 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01635917 0,09507283 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01635917 0,09484374 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01635917 0,09461575 ! neuron migration GO:0001764 79 42 1,000 0,01635917 0,09438886 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01710552 0,09845906 ! glucose transport GO:0015758 65 43 1,000 0,01710552 0,09822407 ! neural tube development GO:0021915 77 43 1,000 0,01710552 0,0979902 ! hexose transport GO:0008645 67 44 1,000 0,01786614 0,10210436 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01786614 0,10186241 ! male sex differentiation GO:0046661 76 44 1,000 0,01786614 0,1016216 ! B cell differentiation GO:0030183 107 44 1,000 0,01786614 0,10138193 ! developmental growth GO:0048589 82 44 1,000 0,01786614 0,10114338 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01864088 0,10528158 ! cell growth GO:0016049 84 45 1,000 0,01864088 0,10503502 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01942959 0,10922334 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01942959 0,10896874 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02023212 0,11320579 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02023212 0,11294313 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,02104834 0,11722758 ! mitochondrial transport GO:0006839 82 48 1,000 0,02104834 0,11695684 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02104834 0,11668736 ! activation of caspase activity GO:0006919 84 48 1,000 0,02104834 0,11641911 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02104834 0,11615209 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,0218781 0,12045472 ! regulation of action potential GO:0001508 95 49 1,000 0,0218781 0,12017971 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,0218781 0,11990596 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0218781 0,11963344 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,02272126 0,12396226 ! regulation of ossification GO:0030278 117 50 1,000 0,02272126 0,1236818 ! histone modification GO:0016570 91 50 1,000 0,02272126 0,12340261 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02272126 0,12312467 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02302912 0,12451247 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02302912 0,1242333 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02302912 0,12395537 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02302912 0,12367869 ! neuron fate determination GO:0048664 7 5 0,000 0,02302912 0,12340323 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02302912 0,123129 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02302912 0,12285599 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02302912 0,12258418 ! polyol transport GO:0015791 12 5 0,000 0,02302912 0,12231358 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02302912 0,12204417 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02302912 0,12177594 ! response to superoxide GO:0000303 10 5 0,000 0,02302912 0,12150888 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02302912 0,121243 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02302912 0,12097828 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02302912 0,12071471 ! female meiosis GO:0007143 7 5 0,000 0,02302912 0,12045228 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02302912 0,120191 ! cobalt ion transport GO:0006824 11 5 0,000 0,02302912 0,11993085 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02302912 0,11967182 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02302912 0,1194139 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02302912 0,1191571 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02302912 0,1189014 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02302912 0,11864679 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02302912 0,11839327 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02302912 0,11814083 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02302912 0,11788947 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02302912 0,11763917 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02302912 0,11738994 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02302912 0,11714176 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02302912 0,11689462 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02302912 0,11664853 ! negative chemotaxis GO:0050919 14 5 0,000 0,02302912 0,11640347 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02302912 0,11615944 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02302912 0,11591642 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02302912 0,11567443 ! behavioral response to pain GO:0048266 9 5 0,000 0,02302912 0,11543344 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02302912 0,11519345 ! Notch receptor processing GO:0007220 8 5 0,000 0,02302912 0,11495446 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02302912 0,11471646 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02302912 0,11447944 ! micturition GO:0060073 9 5 0,000 0,02302912 0,1142434 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02302912 0,11400834 ! copulation GO:0007620 9 5 0,000 0,02302912 0,11377423 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02302912 0,11354109 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02302912 0,1133089 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02302912 0,11307766 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02302912 0,11284735 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02302912 0,11261799 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02302912 0,11238956 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02302912 0,11216205 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02302912 0,11193546 ! grooming behavior GO:0007625 6 5 0,000 0,02302912 0,11170978 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02302912 0,11148501 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02302912 0,11126115 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02302912 0,11103818 ! response to protozoan GO:0001562 10 5 0,000 0,02302912 0,1108161 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02302912 0,11059491 ! lymph vessel development GO:0001945 10 5 0,000 0,02302912 0,1103746 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02302912 0,11015517 ! endochondral ossification GO:0001958 16 5 0,000 0,02302912 0,10993661 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02302912 0,10971891 ! parathyroid gland development GO:0060017 13 5 0,000 0,02302912 0,10950208 ! anagen GO:0042640 6 5 0,000 0,02302912 0,1092861 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02302912 0,10907097 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02302912 0,10885668 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02302912 0,10864324 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02302912 0,10843063 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02302912 0,10821885 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02302912 0,1080079 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02302912 0,10779776 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02302912 0,10758845 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02302912 0,10737994 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02302912 0,10717225 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02302912 0,10696535 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02302912 0,10675925 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02302912 0,10655394 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02302912 0,10634943 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02302912 0,10614569 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02302912 0,10594274 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02302912 0,10574056 ! histidine catabolic process GO:0006548 6 5 0,000 0,02302912 0,10553914 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02302912 0,1053385 ! microvillus organization GO:0032528 7 5 0,000 0,02302912 0,10513862 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02302912 0,10493949 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02302912 0,10474112 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02302912 0,10454349 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02302912 0,10434661 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02302912 0,10415047 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02302912 0,10395507 ! polyol catabolic process GO:0046174 7 5 0,000 0,02302912 0,1037604 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02302912 0,10356645 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02302912 0,10337323 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02302912 0,10318073 ! muscle cell migration GO:0014812 8 5 0,000 0,02302912 0,10298894 ! mitochondrial fission GO:0000266 8 5 0,000 0,02302912 0,10279787 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02302912 0,1026075 ! mRNA transcription GO:0009299 9 5 0,000 0,02302912 0,10241784 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02302912 0,10222888 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02302912 0,10204061 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02302912 0,10185304 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02302912 0,10166615 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02302912 0,10147995 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02302912 0,10129443 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02302912 0,10110958 ! response to food GO:0032094 6 5 0,000 0,02302912 0,10092541 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02302912 0,10074191 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02302912 0,10055908 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02302912 0,1003769 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02302912 0,10019539 ! forebrain neuron development GO:0021884 13 5 0,000 0,02302912 0,10001453 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02302912 0,09983433 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02302912 0,09965477 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02302912 0,09947585 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02302912 0,09929758 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02302912 0,09911995 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02302912 0,09894295 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02302912 0,09876658 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02302912 0,09859084 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02302912 0,09841572 ! basic amino acid transport GO:0015802 11 5 0,000 0,02302912 0,09824123 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02302912 0,09806735 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02302912 0,09789408 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02302912 0,09772143 ! depyrimidination GO:0045008 10 5 0,000 0,02302912 0,09754939 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02302912 0,09737795 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02302912 0,09720711 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02302912 0,09703687 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02302912 0,09686722 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02302912 0,09669817 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02302912 0,09652971 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02302912 0,09636183 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02302912 0,09619453 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02302912 0,09602782 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02302912 0,09586168 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02302912 0,09569612 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02302912 0,09553112 ! response to arsenic GO:0046685 10 5 0,000 0,02302912 0,0953667 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02302912 0,09520284 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02302912 0,09503954 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02302912 0,0948768 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02302912 0,09471462 ! response to cadmium ion GO:0046686 7 5 0,000 0,02302912 0,09455299 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02302912 0,09439191 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02302912 0,09423138 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02302912 0,09407139 ! decidualization GO:0046697 11 5 0,000 0,02302912 0,09391195 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02302912 0,09375305 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02302912 0,09359468 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02302912 0,09343685 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02302912 0,09327955 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02302912 0,09312277 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02302912 0,09296653 ! neural tube patterning GO:0021532 7 5 0,000 0,02302912 0,09281081 ! embryonic cleavage GO:0040016 6 5 0,000 0,02302912 0,0926556 ! peroxisome fission GO:0016559 5 5 0,000 0,02302912 0,09250092 ! histone demethylation GO:0016577 10 5 0,000 0,02302912 0,09234675 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02302912 0,0921931 ! mitotic recombination GO:0006312 9 5 0,000 0,02302912 0,09203995 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02302912 0,09188732 ! metaphase plate congression GO:0051310 7 5 0,000 0,02302912 0,09173518 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02302912 0,09158356 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02302912 0,09143243 ! enteric nervous system development GO:0048484 8 5 0,000 0,02302912 0,0912818 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02302912 0,09113166 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02302912 0,09098202 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02302912 0,09083287 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02302912 0,09068421 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02302912 0,09053603 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02302912 0,09038834 ! plasminogen activation GO:0031639 5 5 0,000 0,02302912 0,09024113 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02302912 0,09009439 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02302912 0,08994813 ! metaphase GO:0051323 8 5 0,000 0,02302912 0,08980235 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02302912 0,08965704 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02302912 0,0895122 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02302912 0,08936782 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02302912 0,08922391 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02302912 0,08908047 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02302912 0,08893748 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02302912 0,08879495 ! response to redox state GO:0051775 5 5 0,000 0,02302912 0,08865288 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02302912 0,08851126 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02302912 0,0883701 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02302912 0,08822938 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02302912 0,08808911 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02302912 0,08794929 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02302912 0,08780991 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02302912 0,08767097 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02302912 0,08753247 ! striatum development GO:0021756 9 5 0,000 0,02302912 0,0873944 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02302912 0,08725677 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02302912 0,08711958 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02302912 0,08698281 ! glial cell migration GO:0008347 11 5 0,000 0,02302912 0,08684648 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02302912 0,08671057 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02302912 0,08657508 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02302912 0,08644002 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02302912 0,08630538 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02302912 0,08617115 ! neuroprotection GO:0043526 6 5 0,000 0,02302912 0,08603735 ! neural plate development GO:0001840 8 5 0,000 0,02302912 0,08590396 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02302912 0,08577098 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02302912 0,08563841 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02302912 0,08550625 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02302912 0,0853745 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02302912 0,08524316 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02302912 0,08511221 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02302912 0,08498167 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02302912 0,08485153 ! spindle assembly GO:0051225 6 5 0,000 0,02302912 0,08472179 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02302912 0,08459244 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02302912 0,08446349 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02302912 0,08433493 ! drug metabolic process GO:0017144 6 5 0,000 0,02302912 0,08420676 ! stem cell division GO:0017145 11 5 0,000 0,02302912 0,08407898 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02302912 0,08395159 ! organ regeneration GO:0031100 7 5 0,000 0,02302912 0,08382459 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02302912 0,08369796 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02302912 0,08357172 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02302912 0,08344586 ! positive regulation of binding GO:0051099 78 51 1,000 0,02357768 0,0853051 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,02357768 0,08517702 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,02357768 0,08504932 ! vesicle organization GO:0016050 107 51 1,000 0,02357768 0,084922 ! regulation of cell shape GO:0008360 125 51 1,000 0,02357768 0,08479506 ! positive regulation of growth GO:0045927 90 52 1,000 0,02444721 0,08779104 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02444721 0,08766021 ! synapse organization GO:0050808 85 52 1,000 0,02444721 0,08752976 ! regulation of translational initiation GO:0006446 82 53 1,000 0,02532973 0,09055473 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,02532973 0,09042038 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02532973 0,09028642 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02622509 0,0933396 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02622509 0,09320172 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,02622509 0,09306426 ! cell recognition GO:0008037 85 54 1,000 0,02622509 0,0929272 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02713315 0,09600349 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02713315 0,09586251 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02713315 0,09572195 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,02713315 0,0955818 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,02713315 0,09544206 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02757135 0,09684187 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02757135 0,0967007 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02757135 0,09655994 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02757135 0,09641959 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02757135 0,09627965 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02757135 0,09614012 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02757135 0,09600098 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02757135 0,09586225 ! sleep GO:0030431 13 6 0,000 0,02757135 0,09572392 ! response to oxygen radical GO:0000305 11 6 0,000 0,02757135 0,09558599 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02757135 0,09544846 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02757135 0,09531132 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02757135 0,09517458 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02757135 0,09503822 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02757135 0,09490226 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02757135 0,09476669 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02757135 0,0946315 ! forebrain regionalization GO:0021871 8 6 0,000 0,02757135 0,0944967 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02757135 0,09436228 ! male meiosis GO:0007140 7 6 0,000 0,02757135 0,09422824 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02757135 0,09409458 ! response to zinc ion GO:0010043 9 6 0,000 0,02757135 0,0939613 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02757135 0,0938284 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02757135 0,09369588 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02757135 0,09356372 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02757135 0,09343194 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02757135 0,09330053 ! malate metabolic process GO:0006108 11 6 0,000 0,02757135 0,09316949 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02757135 0,09303882 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02757135 0,09290852 ! protein refolding GO:0042026 15 6 0,000 0,02757135 0,09277857 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02757135 0,09264899 ! opsonization GO:0008228 8 6 0,000 0,02757135 0,09251978 ! mating behavior GO:0007617 7 6 0,000 0,02757135 0,09239092 ! neuron remodeling GO:0016322 15 6 0,000 0,02757135 0,09226242 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02757135 0,09213428 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02757135 0,09200649 ! equilibrioception GO:0050957 14 6 0,000 0,02757135 0,09187906 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02757135 0,09175198 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02757135 0,09162525 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02757135 0,09149887 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02757135 0,09137284 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02757135 0,09124715 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02757135 0,09112181 ! toxin metabolic process GO:0009404 11 6 0,000 0,02757135 0,09099682 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02757135 0,09087216 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02757135 0,09074785 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02757135 0,09062388 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02757135 0,09050025 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02757135 0,09037695 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02757135 0,09025399 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02757135 0,09013136 ! thymic T cell selection GO:0045061 12 6 0,000 0,02757135 0,09000906 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02757135 0,0898871 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02757135 0,08976547 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02757135 0,08964416 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02757135 0,08952318 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02757135 0,08940253 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02757135 0,08928221 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02757135 0,0891622 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02757135 0,08904252 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02757135 0,08892316 ! hyperosmotic response GO:0006972 9 6 0,000 0,02757135 0,08880412 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02757135 0,0886854 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02757135 0,088567 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02757135 0,08844891 ! urea metabolic process GO:0019627 7 6 0,000 0,02757135 0,08833113 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02757135 0,08821367 ! neutrophil activation GO:0042119 8 6 0,000 0,02757135 0,08809652 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02757135 0,08797968 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02757135 0,08786315 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02757135 0,08774693 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02757135 0,08763102 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02757135 0,08751541 ! neuron apoptosis GO:0051402 9 6 0,000 0,02757135 0,08740011 ! nucleoside salvage GO:0043174 9 6 0,000 0,02757135 0,08728511 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02757135 0,08717041 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02757135 0,08705601 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02757135 0,08694191 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02757135 0,08682812 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02757135 0,08671461 ! carnitine transport GO:0015879 10 6 0,000 0,02757135 0,08660141 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02757135 0,0864885 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02757135 0,08637589 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02757135 0,08626356 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02757135 0,08615153 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02757135 0,08603979 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02757135 0,08592834 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02757135 0,08581718 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02757135 0,0857063 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02757135 0,08559572 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02757135 0,08548541 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02757135 0,08537539 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02757135 0,08526566 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02757135 0,0851562 ! response to UV-C GO:0010225 11 6 0,000 0,02757135 0,08504703 ! astrocyte development GO:0014002 15 6 0,000 0,02757135 0,08493813 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02757135 0,08482951 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02757135 0,08472117 ! interaction with symbiont GO:0051702 13 6 0,000 0,02757135 0,08461311 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02757135 0,08450532 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02757135 0,08439781 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02757135 0,08429057 ! response to copper ion GO:0046688 10 6 0,000 0,02757135 0,0841836 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02757135 0,08407691 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02757135 0,08397048 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02757135 0,08386432 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02757135 0,08375843 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02757135 0,08365281 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02757135 0,08354746 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02757135 0,08344236 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02757135 0,08333754 ! hair follicle maturation GO:0048820 7 6 0,000 0,02757135 0,08323297 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02757135 0,08312867 ! Schwann cell development GO:0014044 15 6 0,000 0,02757135 0,08302463 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02757135 0,08292085 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02757135 0,08281733 ! subpallium development GO:0021544 10 6 0,000 0,02757135 0,08271406 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02757135 0,08261106 ! histone ubiquitination GO:0016574 8 6 0,000 0,02757135 0,08250831 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02757135 0,08240581 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02757135 0,08230357 ! G2 phase GO:0051319 16 6 0,000 0,02757135 0,08220159 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02757135 0,08209985 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02757135 0,08199837 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02757135 0,08189714 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02757135 0,08179615 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02757135 0,08169542 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02757135 0,08159493 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02757135 0,08149469 ! receptor internalization GO:0031623 10 6 0,000 0,02757135 0,0813947 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02757135 0,08129495 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02757135 0,08119545 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02757135 0,08109619 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02757135 0,08099717 ! protein deubiquitination GO:0016579 14 6 0,000 0,02757135 0,08089839 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02757135 0,08079985 ! protein destabilization GO:0031648 9 6 0,000 0,02757135 0,08070156 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02757135 0,0806035 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02757135 0,08050568 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02757135 0,0804081 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02757135 0,08031075 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02757135 0,08021364 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02757135 0,08011676 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02757135 0,08002012 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02757135 0,07992371 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02757135 0,07982753 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02757135 0,07973159 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02757135 0,07963587 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02757135 0,07954038 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02757135 0,07944513 ! catecholamine transport GO:0051937 9 6 0,000 0,02757135 0,0793501 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02757135 0,07925529 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02757135 0,07916072 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02757135 0,07906636 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02757135 0,07897224 ! maternal placenta development GO:0001893 12 6 0,000 0,02757135 0,07887834 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02757135 0,07878466 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02757135 0,0786912 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02757135 0,07859796 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02757135 0,07850495 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02757135 0,07841215 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02757135 0,07831957 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02757135 0,07822722 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02805379 0,07950226 ! muscle fiber development GO:0048747 112 57 1,000 0,02898686 0,08204987 ! lipid modification GO:0030258 97 57 1,000 0,02898686 0,08195345 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02898686 0,08185726 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02898686 0,0817613 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02993223 0,08432899 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,03088978 0,08692491 ! DNA catabolic process GO:0006308 86 59 1,000 0,03088978 0,08682337 ! kidney development GO:0001822 122 60 1,000 0,03185936 0,08944412 ! tRNA transcription GO:0009304 14 7 0,000 0,03209263 0,08999401 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03209263 0,08988924 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03209263 0,08978472 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03209263 0,08968044 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03209263 0,0895764 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03209263 0,08947261 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03209263 0,08936905 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03209263 0,08926573 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03209263 0,08916266 ! prostate gland development GO:0030850 13 7 0,000 0,03209263 0,08905981 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03209263 0,08895721 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03209263 0,08885484 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03209263 0,08875271 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03209263 0,08865081 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03209263 0,08854915 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03209263 0,08844772 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03209263 0,08834652 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03209263 0,08824555 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03209263 0,08814482 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03209263 0,08804431 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03209263 0,08794403 ! glycolipid transport GO:0046836 10 7 0,000 0,03209263 0,08784398 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03209263 0,08774416 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03209263 0,08764456 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03209263 0,08754519 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03209263 0,08744605 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03209263 0,08734713 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03209263 0,08724843 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03209263 0,08714995 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03209263 0,0870517 ! pericardium development GO:0060039 14 7 0,000 0,03209263 0,08695367 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03209263 0,08685586 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03209263 0,08675827 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03209263 0,0866609 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03209263 0,08656374 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03209263 0,08646681 ! lipoprotein transport GO:0042953 14 7 0,000 0,03209263 0,08637009 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03209263 0,08627359 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03209263 0,0861773 ! rhythmic behavior GO:0007622 15 7 0,000 0,03209263 0,08608123 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03209263 0,08598537 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03209263 0,08588972 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03209263 0,08579429 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03209263 0,08569907 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03209263 0,08560406 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03209263 0,08550926 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03209263 0,08541467 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03209263 0,08532029 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03209263 0,08522611 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03209263 0,08513215 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03209263 0,08503839 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03209263 0,08494484 ! spinal cord patterning GO:0021511 13 7 0,000 0,03209263 0,08485149 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03209263 0,08475835 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03209263 0,08466542 ! adrenal gland development GO:0030325 17 7 0,000 0,03209263 0,08457268 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03209263 0,08448015 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03209263 0,08438782 ! ovulation GO:0030728 9 7 0,000 0,03209263 0,0842957 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03209263 0,08420377 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03209263 0,08411205 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03209263 0,08402052 ! microtubule nucleation GO:0007020 20 7 0,000 0,03209263 0,0839292 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03209263 0,08383807 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03209263 0,08374714 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03209263 0,0836564 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03209263 0,08356587 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03209263 0,08347552 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03209263 0,08338538 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03209263 0,08329543 ! galactose metabolic process GO:0006012 13 7 0,000 0,03209263 0,08320567 ! vesicle fusion GO:0006906 17 7 0,000 0,03209263 0,0831161 ! response to dietary excess GO:0002021 8 7 0,000 0,03209263 0,08302673 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03209263 0,08293755 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03209263 0,08284856 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03209263 0,08275976 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03209263 0,08267116 ! purine salvage GO:0043101 10 7 0,000 0,03209263 0,08258274 ! nucleoside transport GO:0015858 8 7 0,000 0,03209263 0,08249451 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03209263 0,08240647 ! parturition GO:0007567 14 7 0,000 0,03209263 0,08231861 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03209263 0,08223095 ! rRNA modification GO:0000154 14 7 0,000 0,03209263 0,08214347 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03209263 0,08205617 ! spindle checkpoint GO:0031577 15 7 0,000 0,03209263 0,08196907 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03209263 0,08188214 ! macrophage differentiation GO:0030225 11 7 0,000 0,03209263 0,0817954 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03209263 0,08170885 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03209263 0,08162247 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03209263 0,08153628 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03209263 0,08145027 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03209263 0,08136445 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03209263 0,0812788 ! fibrinolysis GO:0042730 10 7 0,000 0,03209263 0,08119333 ! eating behavior GO:0042755 7 7 0,000 0,03209263 0,08110805 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03209263 0,08102294 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03209263 0,08093801 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03209263 0,08085326 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03209263 0,08076868 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03209263 0,08068428 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03209263 0,08060006 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03209263 0,08051602 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03209263 0,08043215 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03209263 0,08034845 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03209263 0,08026493 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03209263 0,08018158 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03209263 0,0800984 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03209263 0,0800154 ! regulation of meiosis GO:0040020 12 7 0,000 0,03209263 0,07993257 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03209263 0,07984991 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03209263 0,07976742 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03209263 0,0796851 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03209263 0,07960295 ! transcription termination GO:0006353 13 7 0,000 0,03209263 0,07952097 ! response to tumor cell GO:0002347 13 7 0,000 0,03209263 0,07943916 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03209263 0,07935751 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03209263 0,07927604 ! anaphase GO:0051322 17 7 0,000 0,03209263 0,07919473 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03209263 0,07911359 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03209263 0,07903261 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03209263 0,0789518 ! diuresis GO:0030146 12 7 0,000 0,03209263 0,07887115 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03209263 0,07879067 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03209263 0,07871036 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03209263 0,0786302 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03209263 0,07855021 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03209263 0,07847039 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03209263 0,07839072 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03209263 0,07831122 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03209263 0,07823187 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03209263 0,07815269 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03209263 0,07807367 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03209263 0,07799481 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03209263 0,0779161 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03209263 0,07783756 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03209263 0,07775917 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03209263 0,07768095 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03209263 0,07760287 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03209263 0,07752496 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03209263 0,0774472 ! adult feeding behavior GO:0008343 9 7 0,000 0,03209263 0,0773696 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03209263 0,07729215 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03209263 0,07721486 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03209263 0,07713772 ! muscle adaptation GO:0043500 14 7 0,000 0,03209263 0,07706074 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03209263 0,07698391 ! retina homeostasis GO:0001895 12 7 0,000 0,03209263 0,07690723 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03209263 0,07683071 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03209263 0,07675433 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03209263 0,07667811 ! protein prenylation GO:0018342 18 7 0,000 0,03209263 0,07660204 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03209263 0,07652612 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03209263 0,07645036 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03209263 0,07637474 ! gonad development GO:0008406 98 62 1,000 0,0338341 0,08043958 ! detection of external stimulus GO:0009581 91 63 1,000 0,03483901 0,08274696 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,03585544 0,08507712 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,03585544 0,0849933 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03659303 0,08665632 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03659303 0,08657111 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03659303 0,08648607 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03659303 0,0864012 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03659303 0,08631649 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03659303 0,08623195 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03659303 0,08614757 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03659303 0,08606336 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03659303 0,08597932 ! meiotic prophase I GO:0007128 13 8 0,000 0,03659303 0,08589544 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03659303 0,08581172 ! oligopeptide transport GO:0006857 15 8 0,000 0,03659303 0,08572816 ! UTP metabolic process GO:0046051 8 8 0,000 0,03659303 0,08564477 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03659303 0,08556154 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03659303 0,08547847 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03659303 0,08539556 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03659303 0,08531281 ! succinate metabolic process GO:0006105 14 8 0,000 0,03659303 0,08523022 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03659303 0,0851478 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03659303 0,08506553 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03659303 0,08498342 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03659303 0,08490147 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03659303 0,08481967 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03659303 0,08473804 ! reflex GO:0060004 16 8 0,000 0,03659303 0,08465656 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03659303 0,08457524 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03659303 0,08449407 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03659303 0,08441306 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03659303 0,0843322 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03659303 0,0842515 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03659303 0,08417096 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03659303 0,08409056 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03659303 0,08401033 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03659303 0,08393024 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03659303 0,08385031 ! histidine metabolic process GO:0006547 16 8 0,000 0,03659303 0,08377052 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03659303 0,08369089 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03659303 0,08361142 ! glycine catabolic process GO:0006546 13 8 0,000 0,03659303 0,08353209 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03659303 0,08345291 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03659303 0,08337388 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03659303 0,08329501 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03659303 0,08321628 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03659303 0,0831377 ! macrophage activation GO:0042116 12 8 0,000 0,03659303 0,08305927 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03659303 0,08298098 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03659303 0,08290284 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03659303 0,08282486 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03659303 0,08274701 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03659303 0,08266932 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03659303 0,08259176 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03659303 0,08251436 ! osteoblast development GO:0002076 16 8 0,000 0,03659303 0,0824371 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03659303 0,08235998 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03659303 0,08228301 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03659303 0,08220618 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03659303 0,0821295 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03659303 0,08205296 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03659303 0,08197656 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03659303 0,0819003 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03659303 0,08182418 ! intermediate filament organization GO:0045109 12 8 0,000 0,03659303 0,08174821 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03659303 0,08167238 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03659303 0,08159668 ! cellular extravasation GO:0045123 12 8 0,000 0,03659303 0,08152113 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03659303 0,08144572 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03659303 0,08137044 ! response to antibiotic GO:0046677 11 8 0,000 0,03659303 0,08129531 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03659303 0,08122031 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03659303 0,08114546 ! DNA topological change GO:0006265 12 8 0,000 0,03659303 0,08107074 ! response to tropane GO:0014073 15 8 0,000 0,03659303 0,08099616 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03659303 0,08092171 ! melanosome transport GO:0032402 13 8 0,000 0,03659303 0,0808474 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03659303 0,08077323 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03659303 0,08069919 ! mast cell activation GO:0045576 14 8 0,000 0,03659303 0,08062529 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03659303 0,08055153 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03659303 0,0804779 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03659303 0,0804044 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03659303 0,08033104 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03659303 0,08025781 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03659303 0,08018472 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03659303 0,08011176 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03659303 0,08003893 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03659303 0,07996623 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03659303 0,07989367 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03659303 0,07982123 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03659303 0,07974893 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03659303 0,07967676 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03659303 0,07960472 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03659303 0,07953281 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03659303 0,07946103 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03659303 0,07938938 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03659303 0,07931786 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03659303 0,07924646 ! hormone catabolic process GO:0042447 17 8 0,000 0,03659303 0,0791752 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03659303 0,07910406 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03659303 0,07903305 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03659303 0,07896217 ! ATP catabolic process GO:0006200 11 8 0,000 0,03659303 0,07889142 ! blastocyst growth GO:0001832 19 8 0,000 0,03659303 0,07882079 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03659303 0,07875029 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03659303 0,07867991 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03659303 0,07860966 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03659303 0,07853954 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03659303 0,07846954 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03659303 0,07839966 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03659303 0,07832991 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03659303 0,07826029 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03659303 0,07819078 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03659303 0,0781214 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03659303 0,07805215 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03659303 0,07798301 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03659303 0,077914 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03659303 0,07784511 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03659303 0,07777634 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03659303 0,0777077 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,03688327 0,07825497 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,03688327 0,07818602 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,03688327 0,0781172 ! secondary metabolic process GO:0019748 116 66 1,000 0,03792235 0,0802473 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,03897258 0,08239722 ! adaptive immune response GO:0002250 119 67 1,000 0,03897258 0,08232488 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,04003383 0,08449245 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,04003383 0,0844184 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04107265 0,0865331 ! axon extension GO:0048675 15 9 0,000 0,04107265 0,08645739 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04107265 0,08638181 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04107265 0,08630637 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04107265 0,08623106 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04107265 0,08615588 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04107265 0,08608083 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04107265 0,08600591 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04107265 0,08593113 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04107265 0,08585647 ! phosphate transport GO:0006817 19 9 0,000 0,04107265 0,08578194 ! reproductive behavior GO:0019098 19 9 0,000 0,04107265 0,08570754 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04107265 0,08563327 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04107265 0,08555913 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04107265 0,08548512 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04107265 0,08541123 ! GTP metabolic process GO:0046039 9 9 0,000 0,04107265 0,08533747 ! RNA methylation GO:0001510 15 9 0,000 0,04107265 0,08526384 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04107265 0,08519034 ! artery development GO:0060840 24 9 0,000 0,04107265 0,08511696 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04107265 0,08504371 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04107265 0,08497059 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04107265 0,08489759 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04107265 0,08482472 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04107265 0,08475197 ! chemosensory behavior GO:0007635 20 9 0,000 0,04107265 0,08467934 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04107265 0,08460684 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04107265 0,08453447 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04107265 0,08446222 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04107265 0,08439009 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04107265 0,08431808 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04107265 0,0842462 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04107265 0,08417444 ! protein targeting to ER GO:0045047 22 9 0,000 0,04107265 0,0841028 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04107265 0,08403129 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04107265 0,08395989 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04107265 0,08388862 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04107265 0,08381747 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04107265 0,08374644 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04107265 0,08367552 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04107265 0,08360473 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04107265 0,08353406 ! mannose metabolic process GO:0006013 13 9 0,000 0,04107265 0,08346351 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04107265 0,08339308 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04107265 0,08332276 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04107265 0,08325256 ! receptor clustering GO:0043113 18 9 0,000 0,04107265 0,08318249 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04107265 0,08311253 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04107265 0,08304268 ! ruffle organization GO:0031529 15 9 0,000 0,04107265 0,08297296 ! retinol metabolic process GO:0042572 18 9 0,000 0,04107265 0,08290335 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04107265 0,08283386 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04107265 0,08276448 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04107265 0,08269523 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04107265 0,08262608 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04107265 0,08255705 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04107265 0,08248814 ! segment specification GO:0007379 13 9 0,000 0,04107265 0,08241934 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04107265 0,08235066 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04107265 0,08228209 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04107265 0,08221364 ! response to amine stimulus GO:0014075 13 9 0,000 0,04107265 0,0821453 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04107265 0,08207707 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04107265 0,08200896 ! erythrocyte development GO:0048821 15 9 0,000 0,04107265 0,08194096 ! gas homeostasis GO:0033483 16 9 0,000 0,04107265 0,08187307 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04107265 0,08180529 ! renal water homeostasis GO:0003091 14 9 0,000 0,04107265 0,08173763 ! postreplication repair GO:0006301 22 9 0,000 0,04107265 0,08167008 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04107265 0,08160264 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04107265 0,08153531 ! icosanoid secretion GO:0032309 15 9 0,000 0,04107265 0,08146809 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04107265 0,08140098 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04107265 0,08133399 ! regulation of cell division GO:0051302 15 9 0,000 0,04107265 0,0812671 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04107265 0,08120032 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04107265 0,08113366 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04107265 0,0810671 ! sterol catabolic process GO:0016127 11 9 0,000 0,04107265 0,08100065 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04107265 0,08093431 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04107265 0,08086808 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04107265 0,08080196 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04107265 0,08073594 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04107265 0,08067004 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04107265 0,08060424 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04107265 0,08053854 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04107265 0,08047296 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04107265 0,08040748 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04107265 0,08034211 ! purine base metabolic process GO:0006144 21 9 0,000 0,04107265 0,08027684 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04107265 0,08021168 ! pigment granule transport GO:0051904 17 9 0,000 0,04107265 0,08014663 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04107265 0,08008168 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04107265 0,08001684 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04107265 0,0799521 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04107265 0,07988747 ! mitochondrion localization GO:0051646 15 9 0,000 0,04107265 0,07982294 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,04110597 0,07982321 ! urogenital system development GO:0001655 137 69 1,000 0,04110597 0,07975884 ! appendage morphogenesis GO:0035107 135 70 1,000 0,04218888 0,08179407 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 0,04328243 0,08384665 ! appendage development GO:0048736 136 71 1,000 0,04328243 0,08377919 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,04328243 0,08371184 ! B cell activation GO:0042113 160 71 1,000 0,04328243 0,08364461 ! regulation of caspase activity GO:0043281 122 72 1,000 0,04438652 0,08570944 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04438652 0,08564071 ! carbohydrate transport GO:0008643 110 72 1,000 0,04438652 0,08557209 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,04438652 0,08550357 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,04438652 0,08543517 ! learning or memory GO:0007611 147 73 1,000 0,04550101 0,08751034 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,04550101 0,08744044 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04553159 0,08742938 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04553159 0,08735966 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04553159 0,08729005 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04553159 0,08722055 ! synapsis GO:0007129 13 10 0,000 0,04553159 0,08715116 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04553159 0,08708188 ! N-glycan processing GO:0006491 20 10 0,000 0,04553159 0,08701272 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04553159 0,08694366 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04553159 0,08687471 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04553159 0,08680587 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04553159 0,08673714 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04553159 0,08666852 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04553159 0,08660001 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04553159 0,0865316 ! androgen metabolic process GO:0008209 17 10 0,000 0,04553159 0,08646331 ! phospholipid efflux GO:0033700 16 10 0,000 0,04553159 0,08639512 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04553159 0,08632704 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04553159 0,08625906 ! pathogenesis GO:0009405 13 10 0,000 0,04553159 0,0861912 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04553159 0,08612343 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04553159 0,08605578 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04553159 0,08598823 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04553159 0,08592079 ! endoderm development GO:0007492 16 10 0,000 0,04553159 0,08585346 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04553159 0,08578622 ! arginine catabolic process GO:0006527 13 10 0,000 0,04553159 0,0857191 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04553159 0,08565208 ! proline metabolic process GO:0006560 13 10 0,000 0,04553159 0,08558516 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04553159 0,08551835 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04553159 0,08545165 ! V(D)J recombination GO:0033151 28 10 0,000 0,04553159 0,08538504 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04553159 0,08531854 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04553159 0,08525215 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04553159 0,08518585 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04553159 0,08511967 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04553159 0,08505358 ! multicellular organism growth GO:0035264 18 10 0,000 0,04553159 0,08498759 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04553159 0,08492171 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04553159 0,08485593 ! epithelial cell development GO:0002064 20 10 0,000 0,04553159 0,08479025 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04553159 0,08472468 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04553159 0,0846592 ! macroautophagy GO:0016236 17 10 0,000 0,04553159 0,08459383 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04553159 0,08452856 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04553159 0,08446338 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04553159 0,08439831 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04553159 0,08433334 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04553159 0,08426847 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04553159 0,0842037 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04553159 0,08413902 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04553159 0,08407445 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04553159 0,08400998 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04553159 0,0839456 ! response to dsRNA GO:0043331 20 10 0,000 0,04553159 0,08388132 ! DNA ligation GO:0006266 19 10 0,000 0,04553159 0,08381715 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04553159 0,08375307 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04553159 0,08368908 ! melanosome localization GO:0032400 16 10 0,000 0,04553159 0,0836252 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04553159 0,08356141 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04553159 0,08349772 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04553159 0,08343413 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04553159 0,08337063 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04553159 0,08330723 ! mRNA cleavage GO:0006379 17 10 0,000 0,04553159 0,08324393 ! protein sumoylation GO:0016925 15 10 0,000 0,04553159 0,08318072 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04553159 0,08311761 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04553159 0,08305459 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04553159 0,08299167 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04553159 0,08292885 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04553159 0,08286612 ! salivary gland development GO:0007431 27 10 0,000 0,04553159 0,08280348 ! prophase GO:0051324 15 10 0,000 0,04553159 0,08274094 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04553159 0,0826785 ! apical protein localization GO:0045176 15 10 0,000 0,04553159 0,08261615 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04553159 0,08255389 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04553159 0,08249172 ! midbrain development GO:0030901 13 10 0,000 0,04553159 0,08242965 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04553159 0,08236768 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04553159 0,08230579 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04553159 0,082244 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04553159 0,0821823 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04553159 0,0821207 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04553159 0,08205918 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04553159 0,08199776 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04553159 0,08193643 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04553159 0,08187519 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04553159 0,08181405 ! blastocyst formation GO:0001825 17 10 0,000 0,04553159 0,08175299 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04553159 0,08169203 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04553159 0,08163115 ! activation of innate immune response GO:0002218 12 10 0,000 0,04553159 0,08157037 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04553159 0,08150968 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04553159 0,08144908 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04553159 0,08138857 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04553159 0,08132814 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,04662579 0,08322082 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,04662579 0,08315913 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04776075 0,08512026 ! rhythmic process GO:0048511 128 75 1,000 0,04776075 0,08505726 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04776075 0,08499435 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04890575 0,08696766 ! regulation of catabolic process GO:0009894 161 76 1,000 0,04890575 0,08690343 ! respiratory burst GO:0045730 17 11 0,000 0,04996995 0,08872892 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04996995 0,08866349 ! neuron fate specification GO:0048665 17 11 0,000 0,04996995 0,08859815 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04996995 0,08853291 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04996995 0,08846777 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,04996995 0,08840272 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04996995 0,08833776 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04996995 0,0882729 ! response to pain GO:0048265 24 11 0,000 0,04996995 0,08820814 ! T cell proliferation GO:0042098 26 11 0,000 0,04996995 0,08814347 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04996995 0,0880789 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,04996995 0,08801442 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04996995 0,08795003 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04996995 0,08788574 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04996995 0,08782154 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04996995 0,08775744 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04996995 0,08769343 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04996995 0,08762951 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04996995 0,08756569 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04996995 0,08750196 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04996995 0,08743832 ! lipid digestion GO:0044241 18 11 0,000 0,04996995 0,08737478 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04996995 0,08731132 ! UV protection GO:0009650 19 11 0,000 0,04996995 0,08724796 ! adult heart development GO:0007512 14 11 0,000 0,04996995 0,08718469 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04996995 0,08712152 ! temperature homeostasis GO:0001659 17 11 0,000 0,04996995 0,08705843 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04996995 0,08699544 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04996995 0,08693253 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04996995 0,08686972 ! regulation of organ growth GO:0046620 13 11 0,000 0,04996995 0,086807 ! pigment granule localization GO:0051875 20 11 0,000 0,04996995 0,08674437 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04996995 0,08668183 ! vasoconstriction GO:0042310 18 11 0,000 0,04996995 0,08661938 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04996995 0,08655701 ! embryonic axis specification GO:0000578 18 11 0,000 0,04996995 0,08649474 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04996995 0,08643256 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04996995 0,08637047 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04996995 0,08630847 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04996995 0,08624655 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04996995 0,08618473 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04996995 0,08612299 ! zymogen activation GO:0031638 15 11 0,000 0,04996995 0,08606134 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04996995 0,08599978 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04996995 0,08593831 ! nucleosome positioning GO:0016584 15 11 0,000 0,04996995 0,08587692 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04996995 0,08581563 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04996995 0,08575442 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04996995 0,0856933 ! acid secretion GO:0046717 18 11 0,000 0,04996995 0,08563226 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04996995 0,08557131 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04996995 0,08551045 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04996995 0,08544968 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04996995 0,08538899 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04996995 0,08532838 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,04996995 0,08526787 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04996995 0,08520744 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04996995 0,08514709 ! germ cell migration GO:0008354 25 11 0,000 0,04996995 0,08508683 ! embryonic gut development GO:0048566 15 11 0,000 0,04996995 0,08502666 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04996995 0,08496657 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04996995 0,08490656 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04996995 0,08484664 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04996995 0,08478681 ! defense response to fungus GO:0050832 13 11 0,000 0,04996995 0,08472706 ! lysogeny GO:0030069 21 11 0,000 0,04996995 0,08466739 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04996995 0,08460781 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04996995 0,08454831 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04996995 0,08448889 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04996995 0,08442956 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04996995 0,08437031 ! nucleus localization GO:0051647 19 11 0,000 0,04996995 0,08431115 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04996995 0,08425206 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,0500607 0,08434596 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0500607 0,08428694 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,05122546 0,08618773 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,05122546 0,0861275 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,05239993 0,08804066 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,05239993 0,08797922 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,05239993 0,08791787 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,05239993 0,08785661 ! response to metal ion GO:0010038 140 80 1,000 0,05358399 0,08977931 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05438781 0,09106268 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05438781 0,09099936 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05438781 0,09093612 ! virus-host interaction GO:0019048 29 12 0,000 0,05438781 0,09087297 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05438781 0,09080991 ! mating GO:0007618 17 12 0,000 0,05438781 0,09074693 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05438781 0,09068404 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05438781 0,09062124 ! hippocampus development GO:0021766 26 12 0,000 0,05438781 0,09055853 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05438781 0,0904959 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05438781 0,09043336 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05438781 0,09037091 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05438781 0,09030854 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05438781 0,09024626 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05438781 0,09018406 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05438781 0,09012195 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05438781 0,09005993 ! drug transport GO:0015893 16 12 0,000 0,05438781 0,08999799 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05438781 0,08993613 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05438781 0,08987436 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05438781 0,08981268 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05438781 0,08975108 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05438781 0,08968956 ! forebrain cell migration GO:0021885 21 12 0,000 0,05438781 0,08962813 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05438781 0,08956679 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05438781 0,08950552 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05438781 0,08944434 ! entry into host cell GO:0030260 32 12 0,000 0,05438781 0,08938325 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,05438781 0,08932223 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05438781 0,08926131 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05438781 0,08920046 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05438781 0,0891397 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05438781 0,08907902 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05438781 0,08901842 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05438781 0,0889579 ! protein homotetramerization GO:0051289 21 12 0,000 0,05438781 0,08889747 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05438781 0,08883712 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05438781 0,08877685 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05438781 0,08871666 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05438781 0,08865655 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05438781 0,08859653 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05438781 0,08853659 ! fucose catabolic process GO:0019317 22 12 0,000 0,05438781 0,08847672 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05438781 0,08841694 ! histone methylation GO:0016571 26 12 0,000 0,05438781 0,08835724 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05438781 0,08829762 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05438781 0,08823808 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05438781 0,08817862 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05438781 0,08811924 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05438781 0,08805994 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05438781 0,08800072 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05438781 0,08794158 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05438781 0,08788252 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05438781 0,08782354 ! response to cold GO:0009409 17 12 0,000 0,05438781 0,08776464 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05438781 0,08770581 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05438781 0,08764707 ! T cell activation GO:0042110 168 81 1,000 0,05477753 0,08821603 ! regulation of ligase activity GO:0051340 142 84 1,000 0,05841392 0,09400929 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,05841392 0,09394645 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05878528 0,09448055 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05878528 0,09441747 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05878528 0,09435449 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05878528 0,09429158 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05878528 0,09422876 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05878528 0,09416603 ! lipid localization GO:0010876 28 13 0,000 0,05878528 0,09410338 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05878528 0,09404081 ! organelle fusion GO:0048284 32 13 0,000 0,05878528 0,09397832 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05878528 0,09391592 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05878528 0,0938536 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05878528 0,09379136 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05878528 0,09372921 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05878528 0,09366714 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05878528 0,09360515 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05878528 0,09354324 ! methionine metabolic process GO:0006555 27 13 0,000 0,05878528 0,09348141 ! plasma membrane organization GO:0007009 24 13 0,000 0,05878528 0,09341967 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05878528 0,093358 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05878528 0,09329642 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05878528 0,09323492 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05878528 0,0931735 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05878528 0,09311216 ! response to X-ray GO:0010165 25 13 0,000 0,05878528 0,09305091 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05878528 0,09298973 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05878528 0,09292863 ! exocrine system development GO:0035272 32 13 0,000 0,05878528 0,09286761 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05878528 0,09280668 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05878528 0,09274582 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05878528 0,09268504 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05878528 0,09262435 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05878528 0,09256373 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05878528 0,09250319 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05878528 0,09244273 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05878528 0,09238235 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05878528 0,09232205 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05878528 0,09226182 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05878528 0,09220168 ! ribosome assembly GO:0042255 17 13 0,000 0,05878528 0,09214161 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05878528 0,09208163 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05878528 0,09202172 ! chromatin silencing GO:0006342 26 13 0,000 0,05878528 0,09196188 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05878528 0,09190213 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05878528 0,09184245 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05878528 0,09178285 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05878528 0,09172333 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05878528 0,09166389 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05878528 0,09160452 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05878528 0,09154523 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05878528 0,09148601 ! embryonic placenta development GO:0001892 23 13 0,000 0,05878528 0,09142688 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05878528 0,09136781 ! insulin secretion GO:0030073 23 13 0,000 0,05878528 0,09130883 ! actin filament polymerization GO:0030041 24 13 0,000 0,05878528 0,09124992 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05878528 0,09119109 ! acrosome reaction GO:0007340 18 13 0,000 0,05878528 0,09113233 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05964426 0,09240444 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,06088353 0,09426369 ! regulation of protein transport GO:0051223 154 87 1,000 0,06213162 0,0961342 GO:0070201|regulation of establishment of protein localization, ! rRNA transcription GO:0009303 25 14 0,000 0,06316244 0,09766634 ! lactation GO:0007595 26 14 0,000 0,06316244 0,09760361 ! reproductive cellular process GO:0048610 20 14 0,000 0,06316244 0,09754097 ! tRNA modification GO:0006400 20 14 0,000 0,06316244 0,0974784 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06316244 0,09741591 ! regulation of S phase GO:0033261 23 14 0,000 0,06316244 0,09735351 ! water transport GO:0006833 21 14 0,000 0,06316244 0,09729118 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06316244 0,09722894 ! non-recombinational repair GO:0000726 25 14 0,000 0,06316244 0,09716677 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06316244 0,09710468 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06316244 0,09704267 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06316244 0,09698074 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06316244 0,09691889 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06316244 0,09685712 ! palate development GO:0060021 31 14 0,000 0,06316244 0,09679543 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06316244 0,09673382 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06316244 0,09667228 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06316244 0,09661082 ! arginine metabolic process GO:0006525 17 14 0,000 0,06316244 0,09654944 ! regulation of heart rate GO:0002027 24 14 0,000 0,06316244 0,09648814 ! organic alcohol transport GO:0015850 29 14 0,000 0,06316244 0,09642692 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06316244 0,09636577 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06316244 0,09630471 ! embryo implantation GO:0007566 30 14 0,000 0,06316244 0,09624372 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06316244 0,0961828 ! L-amino acid transport GO:0015807 30 14 0,000 0,06316244 0,09612196 ! bone mineralization GO:0030282 17 14 0,000 0,06316244 0,0960612 ! stem cell development GO:0048864 43 14 0,000 0,06316244 0,09600052 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06316244 0,09593992 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06316244 0,09587939 ! cerebellum development GO:0021549 21 14 0,000 0,06316244 0,09581893 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06316244 0,09575855 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06316244 0,09569825 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06316244 0,09563803 ! cofactor transport GO:0051181 26 14 0,000 0,06316244 0,09557788 ! NADP metabolic process GO:0006739 24 14 0,000 0,06316244 0,0955178 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06316244 0,09545781 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06316244 0,09539788 ! intestinal absorption GO:0050892 25 14 0,000 0,06316244 0,09533803 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06316244 0,09527826 ! oxygen transport GO:0015671 21 14 0,000 0,06316244 0,09521856 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06316244 0,09515894 ! male genitalia development GO:0030539 24 14 0,000 0,06316244 0,09509939 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06316244 0,09503992 ! regulation of DNA binding GO:0051101 155 88 1,000 0,06338842 0,09532033 ! regulation of neurological system process GO:0031644 148 88 1,000 0,06338842 0,0952608 ! cellular defense response GO:0006968 114 89 1,000 0,06465382 0,09710181 ! sex differentiation GO:0007548 145 90 1,000 0,06592772 0,09895328 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06751939 0,10127908 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06751939 0,10121598 ! superoxide anion generation GO:0042554 20 15 0,000 0,06751939 0,10115296 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06751939 0,10109001 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06751939 0,10102714 ! copper ion transport GO:0006825 20 15 0,000 0,06751939 0,10096435 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06751939 0,10090164 ! sulfate transport GO:0008272 23 15 0,000 0,06751939 0,10083901 ! response to cAMP GO:0051591 22 15 0,000 0,06751939 0,10077646 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06751939 0,10071398 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06751939 0,10065158 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06751939 0,10058926 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06751939 0,10052701 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06751939 0,10046484 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06751939 0,10040275 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06751939 0,10034073 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06751939 0,10027879 ! pituitary gland development GO:0021983 29 15 0,000 0,06751939 0,10021693 ! vesicle coating GO:0006901 33 15 0,000 0,06751939 0,10015515 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06751939 0,10009344 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06751939 0,1000318 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06751939 0,09997024 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06751939 0,09990876 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06751939 0,09984736 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06751939 0,09978602 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06751939 0,09972477 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06751939 0,09966359 ! histone deacetylation GO:0016575 20 15 0,000 0,06751939 0,09960248 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06751939 0,09954145 ! tissue regeneration GO:0042246 26 15 0,000 0,06751939 0,09948049 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06751939 0,09941961 ! water homeostasis GO:0030104 27 15 0,000 0,06751939 0,09935881 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06751939 0,09929807 ! muscle maintenance GO:0046716 26 15 0,000 0,06751939 0,09923741 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06751939 0,09917683 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06751939 0,09911632 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06751939 0,09905588 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06751939 0,09899552 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06751939 0,09893523 ! cell killing GO:0001906 29 15 0,000 0,06751939 0,09887501 ! detection of bacterium GO:0016045 18 15 0,000 0,06751939 0,09881487 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06751939 0,0987548 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06751939 0,0986948 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06751939 0,09863488 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06751939 0,09857503 ! peptide hormone processing GO:0016486 23 15 0,000 0,06751939 0,09851525 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06979937 0,10178017 GO:0010498|proteasomal protein catabolic process, ! female pregnancy GO:0007565 164 94 1,000 0,07110622 0,10362299 ! transcription initiation GO:0006352 153 94 1,000 0,07110622 0,10356027 ! regulation of T cell activation GO:0050863 158 94 1,000 0,07110622 0,10349762 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07185622 0,10452604 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07185622 0,10446288 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07185622 0,1043998 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07185622 0,10433679 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07185622 0,10427386 ! bone remodeling GO:0046849 27 16 0,000 0,07185622 0,10421101 ! filopodium assembly GO:0046847 32 16 0,000 0,07185622 0,10414823 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07185622 0,10408553 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07185622 0,1040229 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07185622 0,10396035 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07185622 0,10389787 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07185622 0,10383547 ! startle response GO:0001964 28 16 0,000 0,07185622 0,10377315 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07185622 0,1037109 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07185622 0,10364872 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07185622 0,10358662 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07185622 0,10352459 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07185622 0,10346263 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07185622 0,10340076 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07185622 0,10333895 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07185622 0,10327722 ! response to osmotic stress GO:0006970 25 16 0,000 0,07185622 0,10321556 ! lysosomal transport GO:0007041 26 16 0,000 0,07185622 0,10315398 ! fructose metabolic process GO:0006000 25 16 0,000 0,07185622 0,10309246 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07185622 0,10303103 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07185622 0,10296966 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07185622 0,10290837 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07185622 0,10284715 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07185622 0,10278601 ! axon cargo transport GO:0008088 43 16 0,000 0,07185622 0,10272493 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07185622 0,10266393 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07185622 0,102603 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07185622 0,10254215 ! DNA replication initiation GO:0006270 27 16 0,000 0,07185622 0,10248136 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07185622 0,10242065 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07185622 0,10236001 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07185622 0,10229945 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07185622 0,10223895 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07185622 0,10217852 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07185622 0,10211817 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07185622 0,10205789 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07185622 0,10199768 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07185622 0,10193754 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07185622 0,10187747 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07185622 0,10181747 ! leukocyte differentiation GO:0002521 202 96 1,000 0,07374376 0,10443054 ! mRNA transport GO:0051028 169 96 1,000 0,07374376 0,10436911 ! detection of stimulus GO:0051606 151 96 1,000 0,07374376 0,10430775 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,07507425 0,10612729 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07617302 0,10761732 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07617302 0,10755416 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07617302 0,10749108 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07617302 0,10742807 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07617302 0,10736514 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07617302 0,10730228 ! signal complex assembly GO:0007172 41 17 0,000 0,07617302 0,10723949 ! inositol metabolic process GO:0006020 28 17 0,000 0,07617302 0,10717678 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07617302 0,10711414 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07617302 0,10705157 ! glial cell development GO:0021782 27 17 0,000 0,07617302 0,10698908 ! limbic system development GO:0021761 36 17 0,000 0,07617302 0,10692666 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07617302 0,10686431 ! adult walking behavior GO:0007628 33 17 0,000 0,07617302 0,10680204 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07617302 0,10673983 ! heart looping GO:0001947 30 17 0,000 0,07617302 0,1066777 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07617302 0,10661565 ! myoblast differentiation GO:0045445 45 17 0,000 0,07617302 0,10655366 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07617302 0,10649175 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07617302 0,1064299 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07617302 0,10636813 ! glycine metabolic process GO:0006544 28 17 0,000 0,07617302 0,10630643 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07617302 0,10624481 ! NAD metabolic process GO:0019674 29 17 0,000 0,07617302 0,10618325 ! membrane budding GO:0006900 37 17 0,000 0,07617302 0,10612177 ! DNA integration GO:0015074 29 17 0,000 0,07617302 0,10606036 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07617302 0,10599901 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07617302 0,10593774 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07617302 0,10587654 ! genitalia development GO:0048806 30 17 0,000 0,07617302 0,10581541 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07617302 0,10575435 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07617302 0,10569336 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07617302 0,10563245 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07617302 0,1055716 ! steroid catabolic process GO:0006706 31 17 0,000 0,07617302 0,10551082 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07617302 0,10545011 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07617302 0,10538947 ! gas transport GO:0015669 25 17 0,000 0,07617302 0,1053289 ! organic cation transport GO:0015695 31 17 0,000 0,07617302 0,10526841 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07617302 0,10520798 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07617302 0,10514762 ! microspike assembly GO:0030035 36 17 0,000 0,07617302 0,10508732 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07617302 0,1050271 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08046989 0,11088807 ! neuron maturation GO:0042551 42 18 0,000 0,08046989 0,11082459 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08046989 0,11076119 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08046989 0,11069786 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08046989 0,11063461 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08046989 0,11057142 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08046989 0,11050831 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08046989 0,11044527 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08046989 0,1103823 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08046989 0,11031941 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08046989 0,11025658 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08046989 0,11019383 ! response to fungus GO:0009620 21 18 0,000 0,08046989 0,11013115 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08046989 0,11006854 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08046989 0,110006 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08046989 0,10994353 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08046989 0,10988114 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08046989 0,10981881 ! vitamin transport GO:0051180 27 18 0,000 0,08046989 0,10975655 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08046989 0,10969437 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08046989 0,10963225 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08046989 0,10957021 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08046989 0,10950824 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08046989 0,10944633 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08046989 0,1093845 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08046989 0,10932273 ! protein secretion GO:0009306 39 19 0,000 0,08474692 0,11506833 ! positive regulation of translation GO:0045727 30 19 0,000 0,08474692 0,11500343 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08474692 0,11493861 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08474692 0,11487385 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08474692 0,11480917 ! skin development GO:0043588 36 19 0,000 0,08474692 0,11474456 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08474692 0,11468003 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08474692 0,11461556 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08474692 0,11455117 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08474692 0,11448685 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,08474692 0,11442261 ! cerebral cortex development GO:0021987 36 19 0,000 0,08474692 0,11435843 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08474692 0,11429433 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,08474692 0,1142303 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08474692 0,11416634 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08474692 0,11410246 ! peptide cross-linking GO:0018149 37 19 0,000 0,08474692 0,11403864 ! protein export from nucleus GO:0006611 36 19 0,000 0,08474692 0,1139749 ! heart process GO:0003015 30 19 0,000 0,08474692 0,11391122 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08474692 0,11384762 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08474692 0,11378409 ! visual learning GO:0008542 36 19 0,000 0,08474692 0,11372063 ! G1 phase GO:0051318 40 19 0,000 0,08474692 0,11365724 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08474692 0,11359392 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08474692 0,11353067 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08474692 0,11346749 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08474692 0,11340439 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08474692 0,11334135 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08474692 0,11327838 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08474692 0,11321548 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08474692 0,11315266 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08474692 0,1130899 ! cilium assembly GO:0042384 37 19 0,000 0,08474692 0,11302721 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08474692 0,11296459 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08900419 0,11857369 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08900419 0,11850807 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08900419 0,11844253 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08900419 0,11837705 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08900419 0,11831165 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08900419 0,11824632 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08900419 0,11818106 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08900419 0,11811588 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08900419 0,11805077 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08900419 0,11798572 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08900419 0,11792075 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08900419 0,11785586 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08900419 0,11779103 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08900419 0,11772627 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08900419 0,11766159 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,08900419 0,11759697 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08900419 0,11753243 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08900419 0,11746796 ! body fluid secretion GO:0007589 31 20 0,000 0,08900419 0,11740356 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08900419 0,11733923 ! peptide secretion GO:0002790 35 20 0,000 0,08900419 0,11727497 ! stem cell differentiation GO:0048863 53 20 0,000 0,08900419 0,11721078 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08900419 0,11714666 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08900419 0,11708261 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08900419 0,11701863 ! sensory perception of pain GO:0019233 30 20 0,000 0,08900419 0,11695472 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08900419 0,11689088 ! diencephalon development GO:0021536 34 20 0,000 0,08900419 0,11682711 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08900419 0,11676341 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08900419 0,11669978 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08900419 0,11663621 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08900419 0,11657272 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08900419 0,1165093 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08900419 0,11644594 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08900419 0,11638266 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08900419 0,11631944 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08900419 0,11625629 ! actin filament-based movement GO:0030048 43 20 0,000 0,08900419 0,11619321 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08900419 0,1161302 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08900419 0,11606726 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08900419 0,11600438 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08900419 0,11594157 ! regulation of cell killing GO:0031341 42 21 0,000 0,09324181 0,12139599 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09324181 0,12133033 ! hormone secretion GO:0046879 38 21 0,000 0,09324181 0,12126475 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09324181 0,12119923 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09324181 0,12113379 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09324181 0,12106842 ! axis specification GO:0009798 38 21 0,000 0,09324181 0,12100312 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09324181 0,12093789 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09324181 0,12087273 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09324181 0,12080764 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09324181 0,12074262 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09324181 0,12067767 ! cytolysis GO:0019835 24 21 0,000 0,09324181 0,12061279 ! vasodilation GO:0042311 39 21 0,000 0,09324181 0,12054798 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09324181 0,12048323 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09324181 0,12041856 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09324181 0,12035396 ! DNA modification GO:0006304 34 21 0,000 0,09324181 0,12028943 ! collagen fibril organization GO:0030199 59 21 0,000 0,09324181 0,12022496 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09324181 0,12016057 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,09324181 0,12009624 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09324181 0,12003199 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09324181 0,1199678 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09324181 0,11990368 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09324181 0,11983963 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09324181 0,11977565 ! collagen catabolic process GO:0030574 28 21 0,000 0,09324181 0,11971173 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09324181 0,11964788 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09745985 0,12499381 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09745985 0,12492722 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09745985 0,1248607 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09745985 0,12479425 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09745985 0,12472787 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09745985 0,12466156 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09745985 0,12459532 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09745985 0,12452915 ! keratinization GO:0031424 28 22 0,000 0,09745985 0,12446305 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09745985 0,12439702 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09745985 0,12433107 ! sensory perception of taste GO:0050909 28 22 0,000 0,09745985 0,12426518 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09745985 0,12419936 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09745985 0,12413361 ! vacuolar transport GO:0007034 36 22 0,000 0,09745985 0,12406793 ! lysosome organization GO:0007040 41 22 0,000 0,09745985 0,12400232 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09745985 0,12393678 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09745985 0,12387131 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09745985 0,12380591 ! fucose metabolic process GO:0006004 39 22 0,000 0,09745985 0,12374057 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09745985 0,12367531 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09745985 0,12361012 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09745985 0,12354499 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09745985 0,12347993 ! sarcomere organization GO:0045214 30 22 0,000 0,09745985 0,12341494 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09745985 0,12335002 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09745985 0,12328517 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09745985 0,12322038 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09745985 0,12315567 ! protein stabilization GO:0050821 39 22 0,000 0,09745985 0,12309102 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,1016584 0,1283264 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1016584 0,12825911 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1016584 0,12819189 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1016584 0,12812474 ! gluconeogenesis GO:0006094 33 23 0,000 0,1016584 0,12805765 ! viral genome replication GO:0019079 41 23 0,000 0,1016584 0,12799064 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1016584 0,1279237 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1016584 0,12785683 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1016584 0,12779003 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1016584 0,1277233 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1016584 0,12765664 ! visual behavior GO:0007632 42 23 0,000 0,1016584 0,12759005 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1016584 0,12752353 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1016584 0,12745707 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1016584 0,12739069 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1016584 0,12732437 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1016584 0,12725813 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1016584 0,12719195 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1016584 0,12712584 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,1016584 0,1270598 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,1016584 0,12699383 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1016584 0,12692793 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1016584 0,1268621 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1016584 0,12679633 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1016584 0,12673063 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1016584 0,126665 ! fatty acid transport GO:0015908 44 23 0,000 0,1016584 0,12659944 ! platelet activation GO:0030168 37 23 0,000 0,1016584 0,12653395 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1016584 0,12646852 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1016584 0,12640316 ! hormone transport GO:0009914 40 23 0,000 0,1016584 0,12633787 ! cell-cell recognition GO:0009988 25 23 0,000 0,1016584 0,12627265 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1016584 0,12620749 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1016584 0,1261424 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1016584 0,12607738 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1016584 0,12601243 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10583757 0,13112523 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10583757 0,13105774 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10583757 0,13099033 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10583757 0,13092298 ! vesicle docking GO:0048278 47 24 0,000 0,10583757 0,1308557 ! spinal cord development GO:0021510 47 24 0,000 0,10583757 0,13078849 ! vacuole organization GO:0007033 43 24 0,000 0,10583757 0,13072135 ! digestive system process GO:0022600 39 24 0,000 0,10583757 0,13065428 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10583757 0,13058728 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10583757 0,13052035 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10583757 0,13045348 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10583757 0,13038668 ! membrane depolarization GO:0051899 39 24 0,000 0,10583757 0,13031996 ! pallium development GO:0021543 49 24 0,000 0,10583757 0,1302533 ! pentose metabolic process GO:0019321 35 24 0,000 0,10583757 0,1301867 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10583757 0,13012018 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10583757 0,13005373 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10583757 0,12998734 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10583757 0,12992102 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10583757 0,12985477 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10583757 0,12978858 ! regulation of amine transport GO:0051952 40 24 0,000 0,10583757 0,12972246 ! protein tetramerization GO:0051262 52 24 0,000 0,10583757 0,12965641 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10999743 0,13468388 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10999743 0,13461537 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10999743 0,13454694 ! phototransduction GO:0007602 33 25 0,000 0,10999743 0,13447857 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10999743 0,13441027 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,10999743 0,13434204 ! sperm motility GO:0030317 31 25 0,000 0,10999743 0,13427388 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10999743 0,13420579 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10999743 0,13413777 ! receptor metabolic process GO:0043112 46 25 0,000 0,10999743 0,13406982 ! chromosome condensation GO:0030261 45 25 0,000 0,10999743 0,13400194 ! response to starvation GO:0042594 42 25 0,000 0,10999743 0,13393412 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10999743 0,13386638 ! neural crest cell development GO:0014032 54 25 0,000 0,10999743 0,1337987 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10999743 0,13373109 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10999743 0,13366355 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10999743 0,13359607 ! interaction with host GO:0051701 62 25 0,000 0,10999743 0,13352867 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10999743 0,13346133 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10999743 0,13339406 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10999743 0,13332686 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10999743 0,13325973 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10999743 0,13319266 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10999743 0,13312567 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,10999743 0,13305873 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10999743 0,13299187 ! telomere organization GO:0032200 43 25 0,000 0,10999743 0,13292507 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,10999743 0,13285835 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11413808 0,13779038 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11413808 0,13772127 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11413808 0,13765224 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11413808 0,13758328 ! initiation of viral infection GO:0019059 57 26 0,000 0,11413808 0,13751438 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11413808 0,13744556 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11413808 0,1373768 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11413808 0,13730811 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11413808 0,13723949 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,11413808 0,13717094 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11413808 0,13710246 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11413808 0,13703404 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11413808 0,1369657 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11413808 0,13689742 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11413808 0,13682921 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11413808 0,13676107 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11413808 0,13669299 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,11413808 0,13662499 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11413808 0,13655705 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,11413808 0,13648918 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11413808 0,13642137 ! blastocyst development GO:0001824 49 26 0,000 0,11413808 0,13635364 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11413808 0,13628597 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11413808 0,13621836 ! neuron fate commitment GO:0048663 48 27 0,000 0,1182596 0,14106723 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,1182596 0,14099732 ! iron ion transport GO:0006826 59 27 0,000 0,1182596 0,14092749 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1182596 0,14085772 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1182596 0,14078803 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1182596 0,1407184 ! fat cell differentiation GO:0045444 50 27 0,000 0,1182596 0,14064884 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1182596 0,14057935 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1182596 0,14050993 ! autophagy GO:0006914 41 27 0,000 0,1182596 0,14044057 ! base-excision repair GO:0006284 41 27 0,000 0,1182596 0,14037129 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1182596 0,14030207 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1182596 0,14023292 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1182596 0,14016384 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1182596 0,14009483 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1182596 0,14002589 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1182596 0,13995701 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,12236208 0,14474099 ! circadian rhythm GO:0007623 50 28 0,000 0,12236208 0,14466986 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,12236208 0,14459881 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,12236208 0,14452782 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,12236208 0,1444569 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,12236208 0,14438606 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,12236208 0,14431528 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,12236208 0,14424457 ! synaptogenesis GO:0007416 42 28 0,000 0,12236208 0,14417393 ! lipid oxidation GO:0034440 43 28 0,000 0,12236208 0,14410336 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,12236208 0,14403286 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,12236208 0,14396243 ! translational initiation GO:0006413 65 29 0,000 0,12644561 0,14869411 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12644561 0,14862147 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12644561 0,1485489 ! regulation of pH GO:0006885 43 29 0,000 0,12644561 0,1484764 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12644561 0,14840397 ! catechol metabolic process GO:0009712 54 29 0,000 0,12644561 0,14833161 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12644561 0,14825933 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12644561 0,14818711 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12644561 0,14811497 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12644561 0,14804289 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12644561 0,14797089 ! cell fate determination GO:0001709 60 29 0,000 0,12644561 0,14789895 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12644561 0,14782708 ! detection of light stimulus GO:0009583 38 29 0,000 0,12644561 0,14775529 ! regulation of coagulation GO:0050818 46 29 0,000 0,12644561 0,14768356 ! phenol metabolic process GO:0018958 55 30 0,000 0,13051027 0,15235697 ! zinc ion transport GO:0006829 45 30 0,000 0,13051027 0,15228309 ! membrane docking GO:0022406 61 30 0,000 0,13051027 0,15220927 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13051027 0,15213552 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13051027 0,15206185 ! acute-phase response GO:0006953 49 30 0,000 0,13051027 0,15198825 ! myofibril assembly GO:0030239 47 30 0,000 0,13051027 0,15191472 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,13051027 0,15184126 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13051027 0,15176787 ! phospholipid transport GO:0015914 51 30 0,000 0,13051027 0,15169455 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13051027 0,1516213 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13051027 0,15154813 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,13051027 0,15147502 ! eye morphogenesis GO:0048592 60 30 0,000 0,13051027 0,15140199 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,13455616 0,1560203 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,13455616 0,15594515 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,13455616 0,15587006 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,13455616 0,15579505 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,13455616 0,15572012 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,13455616 0,15564525 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,13455616 0,15557046 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,13455616 0,15549574 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,13455616 0,15542109 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,13455616 0,15534651 ! peptide transport GO:0015833 55 31 0,000 0,13455616 0,155272 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,13455616 0,15519757 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,13455616 0,1551232 ! mesoderm formation GO:0001707 69 31 0,000 0,13455616 0,15504891 ! natural killer cell activation GO:0030101 45 31 0,000 0,13455616 0,15497469 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,13455616 0,15490054 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,13455616 0,15482646 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,13455616 0,15475245 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,13455616 0,15467851 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13858335 0,15923188 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13858335 0,15915587 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13858335 0,15907994 ! cholesterol transport GO:0030301 56 32 0,000 0,13858335 0,15900408 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13858335 0,15892829 ! spliceosome assembly GO:0000245 67 32 0,000 0,13858335 0,15885257 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13858335 0,15877693 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13858335 0,15870136 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,13858335 0,15862586 ! muscle cell development GO:0055001 49 32 0,000 0,13858335 0,15855043 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13858335 0,15847507 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13858335 0,15839979 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13858335 0,15832457 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13858335 0,15824943 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13858335 0,15817436 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13858335 0,15809936 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,13858335 0,15802443 ! gene silencing GO:0016458 65 32 0,000 0,13858335 0,15794957 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,14259194 0,16244139 ! protein targeting to membrane GO:0006612 68 33 0,000 0,14259194 0,16236451 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,14259194 0,16228771 ! ceramide metabolic process GO:0006672 64 33 0,000 0,14259194 0,16221097 ! formation of primary germ layer GO:0001704 72 33 0,000 0,14259194 0,16213431 ! sterol transport GO:0015918 57 33 0,000 0,14259194 0,16205773 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,14259194 0,16198121 ! adult locomotory behavior GO:0008344 59 33 0,000 0,14259194 0,16190477 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,14259194 0,1618284 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,14259194 0,1617521 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14658201 0,16619996 ! glial cell differentiation GO:0010001 63 34 0,000 0,14658201 0,16612167 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14658201 0,16604346 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14658201 0,16596532 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14658201 0,16588726 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14658201 0,16580926 ! mismatch repair GO:0006298 46 34 0,000 0,14658201 0,16573135 ! spermatid development GO:0007286 63 34 0,000 0,14658201 0,1656535 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14658201 0,16557573 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14658201 0,16549803 ! placenta development GO:0001890 53 34 0,000 0,14658201 0,16542041 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,14658201 0,16534285 ! negative regulation of secretion GO:0051048 63 35 0,000 0,15055364 0,16974323 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,15055364 0,16966372 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,15055364 0,16958429 ! odontogenesis GO:0042476 66 35 0,000 0,15055364 0,16950494 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,15055364 0,16942565 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,15055364 0,16934645 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,15055364 0,16926731 ! cytokine production GO:0001816 59 35 0,000 0,15055364 0,16918825 ! vesicle localization GO:0051648 64 35 0,000 0,15055364 0,16910927 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,15450691 0,1734688 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15450691 0,17338789 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,15450691 0,17330705 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,15450691 0,1732263 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15450691 0,17314561 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,15450691 0,17306501 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,15450691 0,17298447 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15450691 0,17290401 ! aerobic respiration GO:0009060 55 36 0,000 0,15450691 0,17282363 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,15450691 0,17274332 ! embryonic organ development GO:0048568 57 36 0,000 0,15450691 0,17266309 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,15450691 0,17258293 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15844192 0,17689618 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15844192 0,17681413 ! sister chromatid segregation GO:0000819 58 37 0,000 0,15844192 0,17673216 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15844192 0,17665026 ! organic anion transport GO:0015711 68 37 0,000 0,15844192 0,17656844 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,15844192 0,1764867 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,15844192 0,17640503 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15844192 0,17632343 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15844192 0,17624192 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15844192 0,17616047 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,15844192 0,17607911 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,16235875 0,18034864 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,16235875 0,18026541 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,16235875 0,18018226 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,16235875 0,18009919 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,16235875 0,1800162 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,16235875 0,17993328 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,16235875 0,17985044 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,16235875 0,17976767 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,16235875 0,17968498 ! mRNA catabolic process GO:0006402 71 39 0,000 0,16625747 0,18391516 ! learning GO:0007612 77 39 0,000 0,16625747 0,18383064 ! organic ether metabolic process GO:0018904 55 39 0,000 0,16625747 0,1837462 ! ion transmembrane transport GO:0034220 66 39 0,000 0,16625747 0,18366184 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,16625747 0,18357755 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,16625747 0,18349334 ! RNA modification GO:0009451 57 39 0,000 0,16625747 0,18340921 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,16625747 0,18332515 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,17013818 0,18751831 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,17013818 0,18743245 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,17013818 0,18734667 ! feeding behavior GO:0007631 59 40 0,000 0,17013818 0,18726096 ! negative regulation of binding GO:0051100 72 40 0,000 0,17013818 0,18717534 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,17013818 0,18708979 ! maintenance of protein location GO:0045185 91 40 0,000 0,17013818 0,18700433 ! cytokinesis GO:0000910 72 40 0,000 0,17013818 0,18691894 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,17400096 0,19107545 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,17400096 0,19098828 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,17400096 0,19090119 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,17400096 0,19081418 ! gliogenesis GO:0042063 88 41 0,000 0,17400096 0,19072724 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,17400096 0,19064039 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,17400096 0,19055362 ! polyol metabolic process GO:0019751 66 41 0,000 0,17400096 0,19046693 ! regulation of tube size GO:0035150 71 42 0,000 0,17784588 0,19458717 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17784588 0,19449872 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17784588 0,19441035 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,17784588 0,19432206 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,17784588 0,19423386 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17784588 0,19414573 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,17784588 0,19405768 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,18167303 0,19814384 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,18167303 0,19805406 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,18167303 0,19796436 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,18167303 0,19787474 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,18167303 0,19778521 ! striated muscle contraction GO:0006941 77 43 0,000 0,18167303 0,19769575 ! phagocytosis GO:0006909 90 43 0,000 0,18167303 0,19760638 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,18167303 0,19751709 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,18548249 0,2015677 ! double-strand break repair GO:0006302 81 44 0,000 0,18548249 0,20147669 ! biopolymer methylation GO:0043414 84 44 0,000 0,18548249 0,20138578 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,18548249 0,20129494 ! maintenance of location in cell GO:0051651 97 44 0,000 0,18548249 0,20120418 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18927435 0,20522491 ! glycolysis GO:0006096 65 45 0,000 0,18927435 0,20513247 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,18927435 0,20504011 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18927435 0,20494783 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,18927435 0,20485564 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,18927435 0,20476353 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18927435 0,2046715 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18927435 0,20457955 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,19304868 0,20856539 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,19304868 0,20847177 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,19304868 0,20837825 ! response to calcium ion GO:0051592 81 47 0,000 0,19680556 0,21233819 ! endosome transport GO:0016197 108 47 0,000 0,19680556 0,21224302 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,19680556 0,21214793 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,19680556 0,21205292 ! JNK cascade GO:0007254 91 47 0,000 0,19680556 0,211958 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,19680556 0,21186316 ! methylation GO:0032259 90 47 0,000 0,19680556 0,21176841 ! protein homooligomerization GO:0051260 76 47 0,000 0,19680556 0,21167375 ! Notch signaling pathway GO:0007219 96 48 0,000 0,20054507 0,21559939 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,20054507 0,2155031 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,20054507 0,21540689 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,20054507 0,21531077 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,2042673 0,21920924 ! regulation of ion transport GO:0043269 77 49 0,000 0,2042673 0,21911151 ! peptide metabolic process GO:0006518 76 49 0,000 0,2042673 0,21901387 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2042673 0,21891631 ! endocrine system development GO:0035270 104 49 0,000 0,2042673 0,21881884 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2042673 0,21872146 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2042673 0,21862417 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2042673 0,21852696 ! neuromuscular process GO:0050905 99 50 0,000 0,20797232 0,22239174 ! inner ear development GO:0048839 79 50 0,000 0,20797232 0,22229294 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,20797232 0,22219423 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,20797232 0,22209561 ! viral infectious cycle GO:0019058 99 51 0,000 0,21166021 0,22593366 ! excretion GO:0007588 83 51 0,000 0,21166021 0,22583347 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,21166021 0,22573337 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,21166021 0,22563335 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,21166021 0,22553343 ! membrane fusion GO:0006944 110 52 0,000 0,21533106 0,2293433 ! amino acid activation GO:0043038 92 52 0,000 0,21533106 0,22924183 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,21898493 0,23302863 ! RNA catabolic process GO:0006401 93 53 0,000 0,21898493 0,23292561 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,21898493 0,23282269 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,21898493 0,23271985 ! cell maturation GO:0048469 100 53 0,000 0,21898493 0,2326171 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,21898493 0,23251445 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,22262191 0,23627186 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,22262191 0,23616769 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,22262191 0,2360636 ! chloride transport GO:0006821 90 55 0,000 0,22624207 0,23979666 ! glucose catabolic process GO:0006007 82 55 0,000 0,22624207 0,23969107 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,22624207 0,23958557 ! gastrulation GO:0007369 112 55 0,000 0,22624207 0,23948017 ! heart morphogenesis GO:0003007 97 55 0,000 0,22624207 0,23937485 ! RNA elongation GO:0006354 79 55 0,000 0,22624207 0,23926964 ! nuclear export GO:0051168 97 55 0,000 0,22624207 0,23916451 ! regulation of actin filament length GO:0030832 105 56 0,000 0,22984549 0,24286704 ! sensory perception of smell GO:0007608 80 56 0,000 0,22984549 0,24276043 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22984549 0,24265391 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,22984549 0,24254748 ! regulation of DNA replication GO:0006275 101 56 0,000 0,22984549 0,24244115 ! proton transport GO:0015992 94 56 0,000 0,22984549 0,24233491 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,22984549 0,24222876 ! maintenance of location GO:0051235 118 57 0,000 0,23343225 0,24590105 ! hydrogen transport GO:0006818 97 58 0,000 0,23700243 0,24955267 ! regulation of endocytosis GO:0030100 91 58 0,000 0,23700243 0,2494435 ! adult behavior GO:0030534 99 58 0,000 0,23700243 0,24933443 ! positive regulation of secretion GO:0051047 95 59 0,000 0,2405561 0,2529624 ! regulation of cellular component size GO:0032535 109 59 0,000 0,2405561 0,25285189 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,2405561 0,25274147 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,2405561 0,25263115 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,24409333 0,2562341 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,24409333 0,25612235 ! camera-type eye development GO:0043010 116 60 0,000 0,24409333 0,2560107 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2476142 0,25959032 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2476142 0,25947725 ! mesoderm development GO:0007498 119 61 0,000 0,2476142 0,25936429 ! tRNA processing GO:0008033 89 61 0,000 0,2476142 0,25925143 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2476142 0,25913866 ! viral reproductive process GO:0022415 126 62 0,000 0,2511188 0,2626921 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2511188 0,26257793 ! regulation of mitosis GO:0007088 105 63 0,000 0,25460718 0,26610985 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,25460718 0,2659943 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,25460718 0,26587885 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,25460718 0,2657635 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,25460718 0,26564825 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25807943 0,26915436 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,25807943 0,26903774 ! single fertilization GO:0007338 75 64 0,000 0,25807943 0,26892122 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,26153562 0,27240463 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,26153562 0,27228676 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,26497582 0,27574906 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,26497582 0,27562985 ! developmental maturation GO:0021700 116 66 0,000 0,26497582 0,27551073 ! cell projection assembly GO:0030031 120 66 0,000 0,26497582 0,27539172 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,26840012 0,27883017 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,26840012 0,27870983 ! activation of MAPK activity GO:0000187 115 67 0,000 0,26840012 0,27858959 ! chromosome segregation GO:0007059 113 67 0,000 0,26840012 0,27846946 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,26840012 0,27834943 ! hexose catabolic process GO:0019320 104 67 0,000 0,26840012 0,2782295 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,26840012 0,27810968 ! activation of immune response GO:0002253 105 67 0,000 0,26840012 0,27798996 ! amino acid transport GO:0006865 125 68 0,000 0,27180857 0,28139906 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,27180857 0,28127803 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,27180857 0,2811571 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,27180857 0,28103628 ! viral reproduction GO:0016032 134 68 0,000 0,27180857 0,28091556 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,27180857 0,28079494 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,27520125 0,28417777 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,27520125 0,28405586 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,27520125 0,28393405 ! antigen processing and presentation GO:0019882 104 69 0,000 0,27520125 0,28381235 ! amine catabolic process GO:0009310 117 71 0,000 0,28193961 0,29063698 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,28193961 0,29051251 ! regulation of immune effector process GO:0002697 137 71 0,000 0,28193961 0,29038815 ! acute inflammatory response GO:0002526 113 72 0,000 0,28528543 0,29370849 ! regulation of blood pressure GO:0008217 125 73 0,000 0,28861577 0,29701007 ! fertilization GO:0009566 90 73 0,000 0,28861577 0,29688309 ! transition metal ion transport GO:0000041 126 74 0,000 0,2919307 0,30016464 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2919307 0,30003642 ! exocytosis GO:0006887 133 74 0,000 0,2919307 0,29990831 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,2919307 0,29978031 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,2919307 0,29965242 ! eye development GO:0001654 143 74 0,000 0,2919307 0,29952463 ! organelle localization GO:0051640 136 74 0,000 0,2919307 0,29939696 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,29523029 0,30265193 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,29523029 0,30252304 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,29851462 0,30575827 ! defense response to bacterium GO:0042742 89 76 0,000 0,29851462 0,30562816 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,29851462 0,30549816 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,29851462 0,30536827 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,30178375 0,30858126 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,30178375 0,30845017 ! blood coagulation GO:0007596 146 78 0,000 0,30503776 0,31164367 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,30503776 0,31151139 ! protein oligomerization GO:0051259 139 78 0,000 0,30503776 0,31137923 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,3082767 0,31455206 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3082767 0,31441871 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,31150066 0,31757228 ! muscle cell differentiation GO:0042692 159 80 0,000 0,31150066 0,31743778 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,31150066 0,31730338 ! protein import into nucleus GO:0006606 158 80 0,000 0,31150066 0,3171691 ! inorganic anion transport GO:0015698 138 80 0,000 0,31150066 0,31703494 ! digestion GO:0007586 112 81 0,000 0,3147097 0,32016556 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,3147097 0,32003024 ! nuclear import GO:0051170 161 81 0,000 0,3147097 0,31989503 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,31790389 0,32300539 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,31790389 0,32286904 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,31790389 0,32273281 ! regulation of lyase activity GO:0051339 160 83 0,000 0,32108329 0,32582303 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,32424799 0,32889572 ! hemostasis GO:0007599 158 84 0,000 0,32424799 0,32875712 ! nucleosome assembly GO:0006334 122 85 0,000 0,32739803 0,33181115 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,32739803 0,33167144 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,3305335 0,3347069 ! chromatin assembly GO:0031497 124 86 0,000 0,3305335 0,33456609 ! alcohol catabolic process GO:0046164 130 86 0,000 0,3305335 0,33442539 ! amine transport GO:0015837 155 86 0,000 0,3305335 0,33428482 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,33365445 0,33729941 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,33365445 0,33715775 ! protein localization in nucleus GO:0034504 176 87 0,000 0,33365445 0,3370162 ! cellular respiration GO:0045333 135 88 0,000 0,33676095 0,34001127 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,33676095 0,33986865 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,34293089 0,34595041 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,34293089 0,34580542 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,34293089 0,34566055 ! sterol metabolic process GO:0016125 152 91 0,000 0,34599446 0,34860246 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,34599446 0,34845654 ! nucleosome organization GO:0034728 138 92 0,000 0,34904384 0,35138054 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,34904384 0,35123358 ! vitamin metabolic process GO:0006766 139 92 0,000 0,34904384 0,35108674 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,35207911 0,35399178 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,35207911 0,35384391 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,35510032 0,35673126 ! forebrain development GO:0030900 188 95 0,000 0,35810755 0,35960215 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,35810755 0,35945213 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,36110085 0,36230552 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,36110085 0,3621545 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,36408029 0,36499049 ! protein ubiquitination GO:0016567 217 97 0,000 0,36408029 0,36483848 ! hormone metabolic process GO:0042445 157 97 0,000 0,36408029 0,36468659 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,36704594 0,36750418 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,36704594 0,3673513 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,36999786 0,3701517 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,36999786 0,36999786