pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6289-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 1,659E-07 3,991E-04 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 4,778E-07 5,748E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 2,998E-06 2,405E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 3,016E-06 1,814E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 6,052E-06 2,912E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 6,052E-06 2,427E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 7,712E-06 2,651E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 7,712E-06 2,319E-03 ! cranial nerve morphogenesis GO:0021602 11 7 2,000 7,712E-06 2,062E-03 ! regulation of gene-specific transcription GO:0032583 96 46 4,000 9,018E-06 2,17E-03 ! response to insulin stimulus GO:0032868 95 46 4,000 9,018E-06 1,973E-03 ! protein import into nucleus GO:0006606 158 80 5,000 9,898E-06 1,985E-03 ! nuclear import GO:0051170 161 81 5,000 1,064E-05 1,969E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,228E-05 2,111E-03 ! ER overload response GO:0006983 12 8 2,000 1,228E-05 1,97E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,228E-05 1,847E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,228E-05 1,739E-03 ! protein import into nucleus, translocation GO:0000060 46 24 3,000 1,302E-05 1,741E-03 ! epithelial tube morphogenesis GO:0060562 98 51 4,000 1,508E-05 1,909E-03 ! protein localization in nucleus GO:0034504 176 87 5,000 1,606E-05 1,932E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 3,353E-05 3,842E-03 ! cell cycle arrest GO:0007050 213 100 5,000 3,55E-05 3,882E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 3,571E-05 3,735E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 3,571E-05 3,58E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 3,634E-05 3,498E-03 ! positive regulation of catabolic process GO:0009896 64 32 3,000 4,242E-05 3,925E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 4,739E-05 4,223E-03 ! cranial nerve development GO:0021545 20 12 2,000 4,739E-05 4,073E-03 ! histone acetylation GO:0016573 26 12 2,000 4,739E-05 3,932E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 4,739E-05 3,801E-03 ! lung development GO:0030324 144 67 4,000 5,728E-05 4,446E-03 ! Golgi organization GO:0007030 24 13 2,000 6,134E-05 4,612E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 6,134E-05 4,472E-03 ! respiratory tube development GO:0030323 150 70 4,000 7,073E-05 5,005E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 7,771E-05 5,342E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 7,771E-05 5,194E-03 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 7,771E-05 5,053E-03 ! respiratory system development GO:0060541 153 72 4,000 8,097E-05 5,126E-03 ! intermediate filament cytoskeleton organization GO:0045104 31 15 2,000 9,671E-05 5,966E-03 ! regulation of catabolic process GO:0009894 161 76 4,000 1,048E-04 6,305E-03 ! intermediate filament-based process GO:0045103 32 16 2,000 1,185E-04 6,953E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,259E-04 7,211E-03 ! neural tube development GO:0021915 77 43 3,000 1,381E-04 7,729E-03 ! branched chain family amino acid metabolic process GO:0009081 33 17 2,000 1,432E-04 7,832E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,503E-04 8,037E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,711E-04 8,95E-03 ! nerve development GO:0021675 28 18 2,000 1,711E-04 8,759E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,801E-04 9,026E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,801E-04 8,841E-03 ! tube morphogenesis GO:0035239 176 86 4,000 1,881E-04 9,052E-03 ! heart process GO:0003015 30 19 2,000 2,023E-04 9,543E-03 GO:0060047|heart contraction, ! protein amino acid acetylation GO:0006473 39 20 2,000 2,369E-04 0,01096132 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,369E-04 0,0107545 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,369E-04 0,01055534 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 2,712E-04 0,01186486 ! cell aging GO:0007569 44 21 2,000 2,751E-04 0,01182148 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 2,751E-04 0,01161409 ! positive regulation of growth GO:0045927 90 52 3,000 2,903E-04 0,01204326 ! response to UV GO:0009411 104 53 3,000 3,125E-04 0,01274489 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 3,172E-04 0,0127182 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,172E-04 0,0125097 ! apoptotic nuclear changes GO:0030262 32 22 2,000 3,172E-04 0,01230793 ! ureteric bud development GO:0001657 43 22 2,000 3,172E-04 0,01211257 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,172E-04 0,01192331 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 3,172E-04 0,01173987 ! regulation of protein catabolic process GO:0042176 116 55 3,000 3,606E-04 0,01314418 ! viral genome replication GO:0019079 41 23 2,000 3,631E-04 0,01303911 ! sex determination GO:0007530 47 23 2,000 3,631E-04 0,01284736 ! response to superoxide GO:0000303 10 5 1,000 3,668E-04 0,01278937 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,668E-04 0,01260666 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,668E-04 0,0124291 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,668E-04 0,01225648 ! anagen GO:0042640 6 5 1,000 3,668E-04 0,01208858 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 3,668E-04 0,01192522 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 1,000 3,668E-04 0,01176622 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 3,668E-04 0,0116114 ! microvillus organization GO:0032528 7 5 1,000 3,668E-04 0,0114606 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 3,668E-04 0,01131367 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,668E-04 0,01117046 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,668E-04 0,01103083 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 3,668E-04 0,01089465 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,668E-04 0,01076178 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 3,668E-04 0,01063212 GO:0022011|myelination in the peripheral nervous system, ! regulation of DNA replication GO:0006275 101 56 3,000 3,865E-04 0,0110693 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 4,131E-04 0,0116935 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 4,131E-04 0,01155753 ! leukocyte homeostasis GO:0001776 44 24 2,000 4,131E-04 0,01142469 ! protein tetramerization GO:0051262 52 24 2,000 4,131E-04 0,01129486 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 4,137E-04 0,01118268 ! regulation of bone remodeling GO:0046850 137 57 3,000 4,137E-04 0,01105843 ! positive regulation of cell migration GO:0030335 126 57 3,000 4,137E-04 0,01093691 ! regulation of intracellular transport GO:0032386 101 57 3,000 4,137E-04 0,01081803 ! regulation of tissue remodeling GO:0034103 140 58 3,000 4,422E-04 0,01143998 ! myelination GO:0042552 45 25 2,000 4,673E-04 0,01196196 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 4,673E-04 0,01183605 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 4,673E-04 0,01171276 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 4,673E-04 0,01159201 ! neural tube closure GO:0001843 49 25 2,000 4,673E-04 0,01147372 GO:0060606|tube closure, ! skeletal system morphogenesis GO:0048705 105 59 3,000 4,721E-04 0,01147363 ! embryonic pattern specification GO:0009880 44 26 2,000 5,259E-04 0,01265394 ! molting cycle process GO:0022404 50 26 2,000 5,259E-04 0,01252865 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 2,000 5,259E-04 0,01240582 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 2,000 5,259E-04 0,01228538 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 5,259E-04 0,01216725 ! response to oxygen radical GO:0000305 11 6 1,000 5,48E-04 0,01255594 ! forebrain regionalization GO:0021871 8 6 1,000 5,48E-04 0,01243749 ! neurofilament cytoskeleton organization GO:0060052 12 6 1,000 5,48E-04 0,01232125 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 5,48E-04 0,01220717 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 5,48E-04 0,01209517 ! male sex determination GO:0030238 15 6 1,000 5,48E-04 0,01198522 ! neural nucleus development GO:0048857 14 6 1,000 5,48E-04 0,01187724 ! response to copper ion GO:0046688 10 6 1,000 5,48E-04 0,0117712 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 1,000 5,48E-04 0,01166703 ! hair follicle maturation GO:0048820 7 6 1,000 5,48E-04 0,01156468 ! Schwann cell development GO:0014044 15 6 1,000 5,48E-04 0,01146412 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 5,48E-04 0,01136529 ! removal of superoxide radicals GO:0019430 11 6 1,000 5,48E-04 0,01126815 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 5,48E-04 0,01117266 GO:0007439|ectodermal gut development, ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 5,48E-04 0,01107877 ! negative regulation of smooth muscle contraction GO:0045986 12 6 1,000 5,48E-04 0,01098645 ! viral reproductive process GO:0022415 126 62 3,000 5,705E-04 0,01134358 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 5,89E-04 0,01161633 ! protein amino acid acylation GO:0043543 55 27 2,000 5,89E-04 0,01152189 ! primary neural tube formation GO:0014020 51 27 2,000 5,89E-04 0,01142897 ! base-excision repair GO:0006284 41 27 2,000 5,89E-04 0,01133754 ! positive regulation of cell motion GO:0051272 146 64 3,000 6,436E-04 0,01229029 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 6,568E-04 0,01244211 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 7,293E-04 0,01370768 ! tissue homeostasis GO:0001894 48 29 2,000 7,293E-04 0,01360142 GO:0048871|multicellular organismal homeostasis, ! regulation of helicase activity GO:0051095 15 7 1,000 7,64E-04 0,01414078 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 7,64E-04 0,01403284 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 7,64E-04 0,01392653 ! mRNA stabilization GO:0048255 18 7 1,000 7,64E-04 0,01382182 GO:0043489|RNA stabilization, ! spinal cord patterning GO:0021511 13 7 1,000 7,64E-04 0,01371867 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 1,000 7,64E-04 0,01361705 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 7,64E-04 0,01351692 ! B cell lineage commitment GO:0002326 21 7 1,000 7,64E-04 0,01341826 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 7,64E-04 0,01332103 ! T cell lineage commitment GO:0002360 16 7 1,000 7,64E-04 0,01322519 ! response to tumor cell GO:0002347 13 7 1,000 7,64E-04 0,01313073 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,64E-04 0,0130376 ! retina homeostasis GO:0001895 12 7 1,000 7,64E-04 0,01294579 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 7,655E-04 0,01287924 ! homeostasis of number of cells GO:0048872 114 67 3,000 7,655E-04 0,0127898 ! ensheathment of neurons GO:0007272 57 30 2,000 8,067E-04 0,01338491 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 2,000 8,067E-04 0,01329324 ! negative regulation of kinase activity GO:0033673 131 68 3,000 8,095E-04 0,01324889 ! viral reproduction GO:0016032 134 68 3,000 8,095E-04 0,01315937 ! urogenital system development GO:0001655 137 69 3,000 8,552E-04 0,01380984 ! metanephros development GO:0001656 74 32 2,000 9,767E-04 0,01566585 ! peripheral nervous system development GO:0007422 64 32 2,000 9,767E-04 0,0155621 ! BMP signaling pathway GO:0030509 64 32 2,000 9,767E-04 0,01545972 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,003E-03 0,0157788 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,015E-03 0,01585206 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,015E-03 0,01574979 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,015E-03 0,01564883 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,015E-03 0,01554915 ! negative regulation of muscle contraction GO:0045932 15 8 1,000 1,015E-03 0,01545074 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,015E-03 0,01535357 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,015E-03 0,01525761 ! DNA topological change GO:0006265 12 8 1,000 1,015E-03 0,01516284 ! myeloid cell homeostasis GO:0002262 13 8 1,000 1,015E-03 0,01506924 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,015E-03 0,01497679 ! cell fate specification GO:0001708 52 33 2,000 1,07E-03 0,0156909 ! placenta development GO:0001890 53 34 2,000 1,168E-03 0,01702861 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,168E-03 0,01692603 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,169E-03 0,01683806 ! odontogenesis GO:0042476 66 35 2,000 1,272E-03 0,01821071 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 1,272E-03 0,01810296 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 1,272E-03 0,01799647 ! regulation of microtubule-based process GO:0032886 78 35 2,000 1,272E-03 0,01789123 ! neural tube formation GO:0001841 67 35 2,000 1,272E-03 0,01778721 ! regulation of developmental growth GO:0048638 15 9 1,000 1,299E-03 0,01806993 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,299E-03 0,01796608 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,299E-03 0,01786342 ! regulation of glycolysis GO:0006110 21 9 1,000 1,299E-03 0,01776192 ! keratinocyte proliferation GO:0043616 14 9 1,000 1,299E-03 0,01766157 ! microtubule bundle formation GO:0001578 21 9 1,000 1,299E-03 0,01756235 ! motor axon guidance GO:0008045 16 9 1,000 1,299E-03 0,01746424 ! protein heterooligomerization GO:0051291 16 9 1,000 1,299E-03 0,01736721 ! segment specification GO:0007379 13 9 1,000 1,299E-03 0,01727126 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,299E-03 0,01717637 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,299E-03 0,01708251 ! induction of an organ GO:0001759 14 9 1,000 1,299E-03 0,01698967 ! regulation of proteolysis GO:0030162 72 36 2,000 1,381E-03 0,01796009 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 1,418E-03 0,01833815 ! glycogen metabolic process GO:0005977 61 37 2,000 1,496E-03 0,01924942 ! nucleus organization GO:0006997 67 38 2,000 1,617E-03 0,02069538 ! embryonic epithelial tube formation GO:0001838 72 38 2,000 1,617E-03 0,02058588 ! glucan metabolic process GO:0044042 62 38 2,000 1,617E-03 0,02047754 GO:0006073|cellular glucan metabolic process, ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 1,618E-03 0,02037661 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,618E-03 0,02027048 ! smoothened signaling pathway GO:0007224 16 10 1,000 1,618E-03 0,02016545 ! lung alveolus development GO:0048286 26 10 1,000 1,618E-03 0,02006151 ! pathogenesis GO:0009405 13 10 1,000 1,618E-03 0,01995863 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,618E-03 0,0198568 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,618E-03 0,019756 GO:0005978|glycogen biosynthetic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,618E-03 0,01965622 ! regulation of bone resorption GO:0045124 25 10 1,000 1,618E-03 0,01955745 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,618E-03 0,01945966 GO:0045685|regulation of glial cell differentiation, ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 1,618E-03 0,01936285 ! DNA ligation GO:0006266 19 10 1,000 1,618E-03 0,01926699 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 1,618E-03 0,01917208 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,618E-03 0,0190781 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,618E-03 0,01898504 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,618E-03 0,01889288 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,618E-03 0,01880161 ! localization within membrane GO:0051668 20 10 1,000 1,618E-03 0,01871121 ! mammary gland development GO:0030879 86 39 2,000 1,744E-03 0,02007725 ! segmentation GO:0035282 67 39 2,000 1,744E-03 0,01998165 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,744E-03 0,01988695 ! mitochondrion organization GO:0007005 148 86 3,000 1,938E-03 0,02199966 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,969E-03 0,02224279 ! neuron fate specification GO:0048665 17 11 1,000 1,969E-03 0,02213886 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,969E-03 0,02203588 ! blood vessel remodeling GO:0001974 29 11 1,000 1,969E-03 0,02193387 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,969E-03 0,02183279 ! ventral spinal cord development GO:0021517 21 11 1,000 1,969E-03 0,02173264 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,969E-03 0,0216334 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,969E-03 0,02153507 ! regulation of organ growth GO:0046620 13 11 1,000 1,969E-03 0,02143763 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,969E-03 0,02134106 ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 1,969E-03 0,02124536 ! thymus development GO:0048538 27 11 1,000 1,969E-03 0,02115051 ! embryonic gut development GO:0048566 15 11 1,000 1,969E-03 0,02105651 ! cardiac cell differentiation GO:0035051 31 11 1,000 1,969E-03 0,02096334 ! developmental induction GO:0031128 19 11 1,000 1,969E-03 0,02087099 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 1,969E-03 0,02077945 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,016E-03 0,02118311 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 2,016E-03 0,02109101 ! regulation of protein transport GO:0051223 154 87 3,000 2,022E-03 0,0210635 GO:0070201|regulation of establishment of protein localization, ! ossification GO:0001503 188 90 3,000 2,289E-03 0,02373688 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 2,313E-03 0,02388805 ! energy reserve metabolic process GO:0006112 74 43 2,000 2,313E-03 0,02378597 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,313E-03 0,02368475 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 2,353E-03 0,02399344 ! virus-host interaction GO:0019048 29 12 1,000 2,353E-03 0,0238922 ! cartilage condensation GO:0001502 20 12 1,000 2,353E-03 0,02379181 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,353E-03 0,02369227 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of cell growth GO:0030307 22 12 1,000 2,353E-03 0,02359355 ! autonomic nervous system development GO:0048483 24 12 1,000 2,353E-03 0,02349565 ! T cell homeostasis GO:0043029 25 12 1,000 2,353E-03 0,02339856 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,353E-03 0,02330227 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,353E-03 0,02320677 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,353E-03 0,02311205 ! regulation of steroid biosynthetic process GO:0050810 17 12 1,000 2,353E-03 0,0230181 ! bone development GO:0060348 189 91 3,000 2,383E-03 0,02321068 ! double-strand break repair GO:0006302 81 44 2,000 2,472E-03 0,02397805 ! developmental growth GO:0048589 82 44 2,000 2,472E-03 0,02388175 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,636E-03 0,02537169 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,636E-03 0,0252706 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 2,77E-03 0,02644903 ! plasma membrane organization GO:0007009 24 13 1,000 2,77E-03 0,02634449 ! response to X-ray GO:0010165 25 13 1,000 2,77E-03 0,02624077 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,77E-03 0,02613787 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 2,77E-03 0,02603577 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,77E-03 0,02593446 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,785E-03 0,025974 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,808E-03 0,02608195 ! vascular process in circulatory system GO:0003018 80 47 2,000 2,986E-03 0,02762953 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 3,003E-03 0,02768195 ! regulation of protein localization GO:0032880 176 97 3,000 3,003E-03 0,02757629 ! interphase GO:0051325 213 98 3,000 3,116E-03 0,02850581 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,171E-03 0,02889574 ! morphogenesis of embryonic epithelium GO:0016331 91 48 2,000 3,171E-03 0,0287867 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 3,171E-03 0,02867848 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 3,219E-03 0,02900694 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,219E-03 0,02889871 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,219E-03 0,02879128 ! negative regulation of caspase activity GO:0043154 22 14 1,000 3,219E-03 0,02868464 ! embryo implantation GO:0007566 30 14 1,000 3,219E-03 0,02857879 ! bone mineralization GO:0030282 17 14 1,000 3,219E-03 0,02847372 ! response to gamma radiation GO:0010332 28 14 1,000 3,219E-03 0,02836942 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 3,219E-03 0,02826589 ! regulation of RNA stability GO:0043487 32 14 1,000 3,219E-03 0,0281631 ! regulation of action potential GO:0001508 95 49 2,000 3,362E-03 0,02931095 ! response to temperature stimulus GO:0009266 76 49 2,000 3,362E-03 0,02920513 ! regulation of ossification GO:0030278 117 50 2,000 3,561E-03 0,03081979 ! histone modification GO:0016570 91 50 2,000 3,561E-03 0,03070933 ! positive regulation of cell size GO:0045793 27 15 1,000 3,699E-03 0,03178776 ! superoxide anion generation GO:0042554 20 15 1,000 3,699E-03 0,03167464 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,699E-03 0,03156232 ! copper ion transport GO:0006825 20 15 1,000 3,699E-03 0,03145079 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,699E-03 0,03134005 ! cardiac muscle contraction GO:0060048 26 15 1,000 3,699E-03 0,03123008 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,699E-03 0,03112088 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,699E-03 0,03101245 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 3,699E-03 0,03090477 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,699E-03 0,03079783 ! muscle maintenance GO:0046716 26 15 1,000 3,699E-03 0,03069163 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,699E-03 0,03058616 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 3,699E-03 0,03048141 ! viral infectious cycle GO:0019058 99 51 2,000 3,767E-03 0,03093142 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 3,767E-03 0,03082621 ! embryonic skeletal system development GO:0048706 85 51 2,000 3,767E-03 0,03072171 ! covalent chromatin modification GO:0016569 101 52 2,000 3,98E-03 0,03234801 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 3,98E-03 0,03223909 ! cartilage development GO:0051216 90 52 2,000 3,98E-03 0,03213091 ! synapse organization GO:0050808 85 52 2,000 3,98E-03 0,03202345 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 4,2E-03 0,03368132 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,211E-03 0,033659 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,211E-03 0,03354754 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,211E-03 0,03343682 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 4,211E-03 0,03332683 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,211E-03 0,03321757 GO:0031114|regulation of microtubule depolymerization, ! axon cargo transport GO:0008088 43 16 1,000 4,211E-03 0,03310901 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 4,211E-03 0,03300117 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,211E-03 0,03289402 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,211E-03 0,03278757 ! biomineral formation GO:0031214 20 16 1,000 4,211E-03 0,0326818 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,211E-03 0,03257671 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,211E-03 0,0324723 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 4,662E-03 0,03583282 ! aging GO:0007568 103 55 2,000 4,662E-03 0,0357187 ! heart morphogenesis GO:0003007 97 55 2,000 4,662E-03 0,03560531 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 4,662E-03 0,03549263 ! glial cell development GO:0021782 27 17 1,000 4,753E-03 0,03607652 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 4,753E-03 0,03596307 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,753E-03 0,03585034 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 4,753E-03 0,0357383 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,753E-03 0,03562697 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,753E-03 0,03551633 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,753E-03 0,03540637 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,753E-03 0,03529709 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,753E-03 0,03518848 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,753E-03 0,03508054 ! nucleotide-excision repair GO:0006289 83 56 2,000 4,904E-03 0,03607917 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 5,326E-03 0,03906808 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,326E-03 0,03894933 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 5,326E-03 0,0388313 ! positive regulation of proteolysis GO:0045862 31 18 1,000 5,326E-03 0,03871399 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,326E-03 0,03859738 ! regulation of steroid metabolic process GO:0019218 30 18 1,000 5,326E-03 0,03848147 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,326E-03 0,03836626 ! skin development GO:0043588 36 19 1,000 5,929E-03 0,04258102 ! lipid phosphorylation GO:0046834 35 19 1,000 5,929E-03 0,04245429 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,929E-03 0,04232831 ! neuromuscular junction development GO:0007528 34 19 1,000 5,929E-03 0,04220308 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,929E-03 0,04207859 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 5,929E-03 0,04195483 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,929E-03 0,04183179 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,929E-03 0,04170948 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 5,929E-03 0,04158788 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 5,947E-03 0,04159163 ! kidney development GO:0001822 122 60 2,000 5,947E-03 0,04147108 ! gonad development GO:0008406 98 62 2,000 6,514E-03 0,04529705 ! positive regulation of ossification GO:0045778 47 20 1,000 6,561E-03 0,04549357 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,561E-03 0,04536284 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 6,561E-03 0,04523286 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 6,561E-03 0,04510363 ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 6,561E-03 0,04497513 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,561E-03 0,04484736 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 6,561E-03 0,04472031 ! hindlimb morphogenesis GO:0035137 43 21 1,000 7,223E-03 0,04909124 ! ovarian follicle development GO:0001541 35 21 1,000 7,223E-03 0,04895295 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 7,223E-03 0,04881544 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 7,223E-03 0,04867871 ! vasodilation GO:0042311 39 21 1,000 7,223E-03 0,04854273 ! positive regulation of locomotion GO:0040017 39 21 1,000 7,223E-03 0,04840751 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 7,223E-03 0,04827305 ! gut development GO:0048565 39 21 1,000 7,223E-03 0,04813933 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 7,424E-03 0,04934159 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 2,000 7,424E-03 0,04920566 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 7,913E-03 0,05230719 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 1,000 7,913E-03 0,05216389 ! regulation of chemotaxis GO:0050920 40 22 1,000 7,913E-03 0,05202136 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 7,913E-03 0,05187961 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 7,913E-03 0,05173864 ! activation of MAPK activity GO:0000187 115 67 2,000 8,07E-03 0,05261863 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,633E-03 0,05613495 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,633E-03 0,05598365 ! response to ethanol GO:0045471 46 23 1,000 8,633E-03 0,05583315 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 8,633E-03 0,05568347 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 8,633E-03 0,05553458 ! regulation of viral reproduction GO:0050792 38 23 1,000 8,633E-03 0,05538649 ! regulation of bone mineralization GO:0030500 49 23 1,000 8,633E-03 0,05523918 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,633E-03 0,05509266 ! negative regulation of cell size GO:0045792 134 69 2,000 8,748E-03 0,05568306 ! appendage morphogenesis GO:0035107 135 70 2,000 9,099E-03 0,05776621 GO:0035108|limb morphogenesis, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 9,38E-03 0,05938881 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 9,38E-03 0,05923294 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 9,38E-03 0,05907788 ! spinal cord development GO:0021510 47 24 1,000 9,38E-03 0,05892363 ! regulation of behavior GO:0050795 43 24 1,000 9,38E-03 0,05877018 ! reproductive structure development GO:0048608 113 71 2,000 9,459E-03 0,05911224 ! appendage development GO:0048736 136 71 2,000 9,459E-03 0,0589591 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 2,000 9,827E-03 0,06109234 ! vasculogenesis GO:0001570 46 25 1,000 0,01015477 0,06297007 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 0,01015477 0,06280819 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01015477 0,06264714 ! chromosome condensation GO:0030261 45 25 1,000 0,01015477 0,06248692 ! response to starvation GO:0042594 42 25 1,000 0,01015477 0,06232752 ! osteoblast differentiation GO:0001649 60 25 1,000 0,01015477 0,06216892 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01015477 0,06201113 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 1,000 0,01015477 0,06185414 ! interaction with host GO:0051701 62 25 1,000 0,01015477 0,06169794 ! regulation of biomineral formation GO:0070167 51 25 1,000 0,01015477 0,06154253 ! somitogenesis GO:0001756 43 25 1,000 0,01015477 0,06138791 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01015477 0,06123405 ! axon guidance GO:0007411 139 73 2,000 0,01020243 0,06136763 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01058655 0,0635193 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01095718 0,06557952 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01095718 0,0654168 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01095718 0,06525487 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01137969 0,06760379 ! neuron fate commitment GO:0048663 48 27 1,000 0,01178663 0,06984884 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01178663 0,06967723 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01178663 0,06950645 ! superoxide metabolic process GO:0006801 38 27 1,000 0,01178663 0,06933651 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01178663 0,06916739 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01178663 0,0689991 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01178663 0,06883163 ! protein oligomerization GO:0051259 139 78 2,000 0,01220623 0,07110944 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,0126321 0,07341263 ! dendrite development GO:0016358 59 28 1,000 0,01264277 0,07329763 ! synaptogenesis GO:0007416 42 28 1,000 0,01264277 0,07312143 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01264277 0,07294608 ! response to hypoxia GO:0001666 171 81 2,000 0,01350914 0,07775833 ! regulation of pH GO:0006885 43 29 1,000 0,01352526 0,07766532 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01352526 0,0774804 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01352526 0,07729636 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01352526 0,0771132 ! response to drug GO:0042493 143 82 2,000 0,01396035 0,0794057 ! response to oxygen levels GO:0070482 176 83 2,000 0,01442007 0,08182707 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01443373 0,08171188 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01443373 0,08152007 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01443373 0,08132916 ! eye morphogenesis GO:0048592 60 30 1,000 0,01443373 0,08113914 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01536784 0,08618888 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01536784 0,08598844 ! ovulation cycle process GO:0022602 49 31 1,000 0,01536784 0,08578893 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01536784 0,08559034 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01536784 0,08539267 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01585034 0,08787078 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01632725 0,0903066 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01632725 0,09009947 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01632725 0,0898933 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01632725 0,08968806 ! ovulation cycle GO:0042698 51 32 1,000 0,01632725 0,08948376 ! hindbrain development GO:0030902 61 32 1,000 0,01632725 0,08928039 ! gland development GO:0048732 206 88 2,000 0,01684663 0,09191155 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01731162 0,09423476 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01731162 0,09402204 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01731162 0,09381027 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01731162 0,09359947 ! sex differentiation GO:0007548 145 90 2,000 0,01787726 0,09644101 ! glial cell differentiation GO:0010001 63 34 1,000 0,01832061 0,09861161 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01832061 0,09839149 ! regulation of muscle development GO:0048634 70 35 1,000 0,01935389 0,10370924 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01935389 0,10347878 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01935389 0,10324933 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01935389 0,10302091 ! female gonad development GO:0008585 58 35 1,000 0,01935389 0,10279349 ! telencephalon development GO:0021537 68 35 1,000 0,01935389 0,10256707 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01935389 0,10234165 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01948777 0,10282364 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01948777 0,10259864 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02004186 0,10528538 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02041112 0,1069916 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02041112 0,10675901 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,02041112 0,10652743 ! embryonic organ development GO:0048568 57 36 1,000 0,02041112 0,10629685 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02041112 0,10606727 ! tissue remodeling GO:0048771 76 37 1,000 0,02149197 0,11144329 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02149197 0,11120363 ! protein ubiquitination GO:0016567 217 97 2,000 0,02175591 0,11232774 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02259613 0,11641605 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02259613 0,1161673 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02259613 0,11591961 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02259613 0,11567297 GO:0046660|female sex differentiation, ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02259613 0,11542738 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02294181 0,11694492 GO:0060538|skeletal muscle organ development, ! ear morphogenesis GO:0042471 60 39 1,000 0,02372327 0,12067272 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02487308 0,12625448 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02604522 0,13192592 ! gliogenesis GO:0042063 88 41 1,000 0,02604522 0,13164876 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02604522 0,13137277 ! T cell differentiation GO:0030217 81 41 1,000 0,02604522 0,13109793 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02604522 0,13082424 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02723941 0,13653753 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02723941 0,13625366 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02723941 0,13597098 ! regulation of tube size GO:0035150 71 42 1,000 0,02723941 0,13568947 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02723941 0,13540912 ! neuron migration GO:0001764 79 42 1,000 0,02723941 0,13512992 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02723941 0,13485188 ! glucose transport GO:0015758 65 43 1,000 0,02845531 0,1405821 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02845531 0,14029402 ! striated muscle contraction GO:0006941 77 43 1,000 0,02845531 0,14000712 ! hexose transport GO:0008645 67 44 1,000 0,02969263 0,14579689 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02969263 0,14549995 ! B cell differentiation GO:0030183 107 44 1,000 0,02969263 0,14520422 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02969263 0,14490969 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03017852 0,14698285 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03017852 0,14668592 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03017852 0,14639018 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03017852 0,14609563 ! neuron fate determination GO:0048664 7 5 0,000 0,03017852 0,14580227 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03017852 0,14551008 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03017852 0,14521906 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03017852 0,1449292 ! polyol transport GO:0015791 12 5 0,000 0,03017852 0,14464049 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03017852 0,14435294 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03017852 0,14406652 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03017852 0,14378124 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03017852 0,14349709 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03017852 0,14321406 ! female meiosis GO:0007143 7 5 0,000 0,03017852 0,14293214 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03017852 0,14265133 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03017852 0,14237162 ! cobalt ion transport GO:0006824 11 5 0,000 0,03017852 0,14209301 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03017852 0,14181548 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03017852 0,14153904 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03017852 0,14126367 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03017852 0,14098938 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03017852 0,14071614 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03017852 0,14044396 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03017852 0,14017283 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03017852 0,13990275 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03017852 0,13963371 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03017852 0,1393657 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03017852 0,13909871 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03017852 0,13883275 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03017852 0,1385678 ! negative chemotaxis GO:0050919 14 5 0,000 0,03017852 0,13830386 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03017852 0,13804093 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03017852 0,13777899 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03017852 0,13751805 ! behavioral response to pain GO:0048266 9 5 0,000 0,03017852 0,13725809 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03017852 0,13699911 ! Notch receptor processing GO:0007220 8 5 0,000 0,03017852 0,13674111 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03017852 0,13648408 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03017852 0,13622801 ! micturition GO:0060073 9 5 0,000 0,03017852 0,1359729 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03017852 0,13571874 ! copulation GO:0007620 9 5 0,000 0,03017852 0,13546554 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03017852 0,13521327 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03017852 0,13496195 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03017852 0,13471156 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03017852 0,13446209 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03017852 0,13421355 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03017852 0,13396592 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03017852 0,1337192 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03017852 0,1334734 ! grooming behavior GO:0007625 6 5 0,000 0,03017852 0,13322849 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03017852 0,13298448 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03017852 0,13274137 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03017852 0,13249914 ! response to protozoan GO:0001562 10 5 0,000 0,03017852 0,13225779 ! lymph vessel development GO:0001945 10 5 0,000 0,03017852 0,13201732 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03017852 0,13177773 ! endochondral ossification GO:0001958 16 5 0,000 0,03017852 0,131539 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03017852 0,13130114 ! parathyroid gland development GO:0060017 13 5 0,000 0,03017852 0,13106413 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03017852 0,13082798 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03017852 0,13059268 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03017852 0,13035822 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03017852 0,1301246 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03017852 0,12989182 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03017852 0,12965987 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03017852 0,12942875 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03017852 0,12919845 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03017852 0,12896897 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03017852 0,1287403 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03017852 0,12851244 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03017852 0,12828539 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03017852 0,12805913 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,03017852 0,12783368 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03017852 0,12760901 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03017852 0,12738514 ! histidine catabolic process GO:0006548 6 5 0,000 0,03017852 0,12716205 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03017852 0,12693973 ! valine metabolic process GO:0006573 10 5 0,000 0,03017852 0,1267182 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03017852 0,12649744 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03017852 0,12627744 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03017852 0,12605821 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03017852 0,12583974 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03017852 0,12562202 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03017852 0,12540506 ! polyol catabolic process GO:0046174 7 5 0,000 0,03017852 0,12518884 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03017852 0,12497337 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03017852 0,12475864 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03017852 0,12454465 ! muscle cell migration GO:0014812 8 5 0,000 0,03017852 0,12433138 ! mitochondrial fission GO:0000266 8 5 0,000 0,03017852 0,12411885 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03017852 0,12390704 ! mRNA transcription GO:0009299 9 5 0,000 0,03017852 0,12369596 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03017852 0,12348559 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03017852 0,12327594 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03017852 0,123067 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03017852 0,12285876 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03017852 0,12265123 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03017852 0,1224444 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03017852 0,12223826 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03017852 0,12203282 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03017852 0,12182807 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03017852 0,121624 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03017852 0,12142062 ! forebrain neuron development GO:0021884 13 5 0,000 0,03017852 0,12121791 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03017852 0,12101588 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03017852 0,12081452 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03017852 0,12061383 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03017852 0,12041381 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03017852 0,12021445 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03017852 0,12001575 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03017852 0,1198177 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03017852 0,11962031 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03017852 0,11942357 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03017852 0,11922747 ! basic amino acid transport GO:0015802 11 5 0,000 0,03017852 0,11903201 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03017852 0,1188372 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03017852 0,11864302 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03017852 0,11844948 ! depyrimidination GO:0045008 10 5 0,000 0,03017852 0,11825656 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03017852 0,11806427 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03017852 0,11787261 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03017852 0,11768157 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03017852 0,11749115 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,03017852 0,11730134 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03017852 0,11711214 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03017852 0,11692356 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03017852 0,11673558 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03017852 0,1165482 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03017852 0,11636142 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03017852 0,11617525 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03017852 0,11598966 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03017852 0,11580467 ! response to arsenic GO:0046685 10 5 0,000 0,03017852 0,11562027 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03017852 0,11543645 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03017852 0,11525322 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03017852 0,11507057 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03017852 0,11488849 ! response to cadmium ion GO:0046686 7 5 0,000 0,03017852 0,114707 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03017852 0,11452607 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03017852 0,11434571 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03017852 0,11416592 ! decidualization GO:0046697 11 5 0,000 0,03017852 0,1139867 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03017852 0,11380804 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03017852 0,11362993 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03017852 0,11345239 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03017852 0,1132754 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03017852 0,11309895 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03017852 0,11292306 ! neural tube patterning GO:0021532 7 5 0,000 0,03017852 0,11274771 ! embryonic cleavage GO:0040016 6 5 0,000 0,03017852 0,11257291 ! peroxisome fission GO:0016559 5 5 0,000 0,03017852 0,11239865 ! histone demethylation GO:0016577 10 5 0,000 0,03017852 0,11222493 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03017852 0,11205174 ! mitotic recombination GO:0006312 9 5 0,000 0,03017852 0,11187909 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03017852 0,11170697 ! metaphase plate congression GO:0051310 7 5 0,000 0,03017852 0,11153537 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03017852 0,11136431 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03017852 0,11119376 ! enteric nervous system development GO:0048484 8 5 0,000 0,03017852 0,11102374 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03017852 0,11085424 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03017852 0,11068526 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03017852 0,11051679 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03017852 0,11034883 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03017852 0,11018138 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03017852 0,11001444 ! plasminogen activation GO:0031639 5 5 0,000 0,03017852 0,109848 ! B cell homeostasis GO:0001782 13 5 0,000 0,03017852 0,10968207 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03017852 0,10951663 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03017852 0,1093517 ! metaphase GO:0051323 8 5 0,000 0,03017852 0,10918726 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03017852 0,10902332 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03017852 0,10885986 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03017852 0,1086969 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03017852 0,10853442 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03017852 0,10837243 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03017852 0,10821092 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03017852 0,10804989 ! response to redox state GO:0051775 5 5 0,000 0,03017852 0,10788934 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03017852 0,10772927 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03017852 0,10756967 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03017852 0,10741054 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03017852 0,10725189 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03017852 0,1070937 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03017852 0,10693598 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03017852 0,10677872 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03017852 0,10662192 ! striatum development GO:0021756 9 5 0,000 0,03017852 0,10646558 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03017852 0,1063097 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03017852 0,10615428 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03017852 0,10599931 ! glial cell migration GO:0008347 11 5 0,000 0,03017852 0,10584479 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03017852 0,10569073 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03017852 0,1055371 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03017852 0,10538393 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03017852 0,1052312 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03017852 0,10507891 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03017852 0,10492706 ! neuroprotection GO:0043526 6 5 0,000 0,03017852 0,10477565 ! neural plate development GO:0001840 8 5 0,000 0,03017852 0,10462468 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03017852 0,10447414 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03017852 0,10432403 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03017852 0,10417436 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03017852 0,10402511 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03017852 0,10387629 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03017852 0,1037279 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03017852 0,10357993 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03017852 0,10343238 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03017852 0,10328525 ! spindle assembly GO:0051225 6 5 0,000 0,03017852 0,10313853 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03017852 0,10299224 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03017852 0,10284636 ! drug metabolic process GO:0017144 6 5 0,000 0,03017852 0,10270089 ! stem cell division GO:0017145 11 5 0,000 0,03017852 0,10255583 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03017852 0,10241118 ! organ regeneration GO:0031100 7 5 0,000 0,03017852 0,10226694 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03017852 0,10212311 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03017852 0,10197967 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03017852 0,10183665 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,03095107 0,1042973 ! cell growth GO:0016049 84 45 1,000 0,03095107 0,10415143 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03223031 0,10830466 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03353007 0,11251514 ! mitochondrial transport GO:0006839 82 48 1,000 0,03485005 0,11678164 ! cellular component disassembly GO:0022411 86 48 1,000 0,03485005 0,11661922 ! activation of caspase activity GO:0006919 84 48 1,000 0,03485005 0,11645725 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,03485005 0,11629573 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03610464 0,12031546 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03610464 0,12014904 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03610464 0,11998309 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03610464 0,1198176 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03610464 0,11965256 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03610464 0,11948798 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03610464 0,11932384 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03610464 0,11916016 ! sleep GO:0030431 13 6 0,000 0,03610464 0,11899693 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03610464 0,11883414 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03610464 0,1186718 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03610464 0,1185099 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03610464 0,11834845 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03610464 0,11818743 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03610464 0,11802685 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03610464 0,1178667 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03610464 0,11770699 ! male meiosis GO:0007140 7 6 0,000 0,03610464 0,11754771 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03610464 0,11738886 ! response to zinc ion GO:0010043 9 6 0,000 0,03610464 0,11723044 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03610464 0,11707245 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03610464 0,11691488 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03610464 0,11675774 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03610464 0,11660102 ! malate metabolic process GO:0006108 11 6 0,000 0,03610464 0,11644472 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03610464 0,11628883 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03610464 0,11613337 ! protein refolding GO:0042026 15 6 0,000 0,03610464 0,11597832 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03610464 0,11582368 ! opsonization GO:0008228 8 6 0,000 0,03610464 0,11566945 ! mating behavior GO:0007617 7 6 0,000 0,03610464 0,11551564 ! neuron remodeling GO:0016322 15 6 0,000 0,03610464 0,11536223 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03610464 0,11520923 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03610464 0,11505663 ! equilibrioception GO:0050957 14 6 0,000 0,03610464 0,11490444 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03610464 0,11475265 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03610464 0,11460127 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03610464 0,11445028 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03610464 0,11429968 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03610464 0,11414949 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03610464 0,11399968 ! toxin metabolic process GO:0009404 11 6 0,000 0,03610464 0,11385027 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03610464 0,11370126 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03610464 0,11355263 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03610464 0,11340439 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03610464 0,11325653 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03610464 0,11310906 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03610464 0,11296198 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03610464 0,11281527 ! thymic T cell selection GO:0045061 12 6 0,000 0,03610464 0,11266895 ! protein lipoylation GO:0009249 10 6 0,000 0,03610464 0,112523 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03610464 0,11237744 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03610464 0,11223225 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03610464 0,11208743 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03610464 0,11194299 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03610464 0,11179892 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03610464 0,11165522 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03610464 0,11151189 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03610464 0,11136892 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03610464 0,11122632 ! hyperosmotic response GO:0006972 9 6 0,000 0,03610464 0,11108409 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03610464 0,11094222 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03610464 0,11080071 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03610464 0,11065957 ! urea metabolic process GO:0019627 7 6 0,000 0,03610464 0,11051878 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03610464 0,11037835 ! neutrophil activation GO:0042119 8 6 0,000 0,03610464 0,11023827 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03610464 0,11009855 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03610464 0,10995919 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03610464 0,10982018 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03610464 0,10968151 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03610464 0,1095432 ! neuron apoptosis GO:0051402 9 6 0,000 0,03610464 0,10940524 ! nucleoside salvage GO:0043174 9 6 0,000 0,03610464 0,10926762 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03610464 0,10913035 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03610464 0,10899342 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03610464 0,10885684 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03610464 0,1087206 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03610464 0,1085847 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03610464 0,10844914 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03610464 0,10831391 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03610464 0,10817903 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03610464 0,10804448 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03610464 0,10791026 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03610464 0,10777638 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03610464 0,10764282 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03610464 0,1075096 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03610464 0,10737671 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03610464 0,10724415 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03610464 0,10711191 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03610464 0,10698 ! response to UV-C GO:0010225 11 6 0,000 0,03610464 0,10684841 ! astrocyte development GO:0014002 15 6 0,000 0,03610464 0,10671715 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03610464 0,10658621 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03610464 0,10645559 ! interaction with symbiont GO:0051702 13 6 0,000 0,03610464 0,10632529 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03610464 0,1061953 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03610464 0,10606564 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03610464 0,10593629 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03610464 0,10580726 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03610464 0,10567854 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03610464 0,10555013 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03610464 0,10542204 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03610464 0,10529425 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03610464 0,10516678 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03610464 0,10503961 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03610464 0,10491275 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03610464 0,1047862 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03610464 0,10465995 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03610464 0,10453401 ! subpallium development GO:0021544 10 6 0,000 0,03610464 0,10440836 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03610464 0,10428302 ! histone ubiquitination GO:0016574 8 6 0,000 0,03610464 0,10415798 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03610464 0,10403324 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03610464 0,1039088 ! G2 phase GO:0051319 16 6 0,000 0,03610464 0,10378466 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03610464 0,10366081 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03610464 0,10353726 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03610464 0,103414 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03610464 0,10329103 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03610464 0,10316836 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03610464 0,10304598 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03610464 0,10292389 ! receptor internalization GO:0031623 10 6 0,000 0,03610464 0,10280208 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03610464 0,10268057 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03610464 0,10255934 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03610464 0,1024384 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03610464 0,10231774 ! protein deubiquitination GO:0016579 14 6 0,000 0,03610464 0,10219736 ! protein destabilization GO:0031648 9 6 0,000 0,03610464 0,10207727 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03610464 0,10195746 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03610464 0,10183794 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03610464 0,10171869 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03610464 0,10159972 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03610464 0,10148103 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03610464 0,10136261 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03610464 0,10124447 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03610464 0,10112661 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03610464 0,10100902 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03610464 0,10089171 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03610464 0,10077466 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03610464 0,10065789 ! catecholamine transport GO:0051937 9 6 0,000 0,03610464 0,10054139 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03610464 0,10042515 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03610464 0,10030919 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03610464 0,10019349 ! maternal placenta development GO:0001893 12 6 0,000 0,03610464 0,10007806 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03610464 0,0999629 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03610464 0,099848 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03610464 0,09973336 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03610464 0,09961899 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03610464 0,09950488 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03610464 0,09939103 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03618995 0,09951203 ! peptide metabolic process GO:0006518 76 49 1,000 0,03618995 0,09939843 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03618995 0,09928509 ! inner ear development GO:0048839 79 50 1,000 0,03754949 0,10289758 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03754949 0,10278051 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03754949 0,10266372 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03754949 0,10254719 ! positive regulation of binding GO:0051099 78 51 1,000 0,03892838 0,10619237 ! chromatin remodeling GO:0006338 109 51 1,000 0,03892838 0,10607211 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,03892838 0,10595212 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,03892838 0,1058324 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,04032632 0,10950918 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,04032632 0,10938572 ! amino acid activation GO:0043038 92 52 1,000 0,04032632 0,10926254 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! tRNA transcription GO:0009304 14 7 0,000 0,04199474 0,11365505 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04199474 0,11352734 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04199474 0,11339993 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04199474 0,1132728 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04199474 0,11314595 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04199474 0,11301939 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04199474 0,11289311 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04199474 0,11276712 ! prostate gland development GO:0030850 13 7 0,000 0,04199474 0,1126414 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04199474 0,11251596 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04199474 0,11239081 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04199474 0,11226593 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04199474 0,11214133 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04199474 0,112017 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04199474 0,11189295 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04199474 0,11176918 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04199474 0,11164567 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04199474 0,11152245 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04199474 0,11139949 ! glycolipid transport GO:0046836 10 7 0,000 0,04199474 0,1112768 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04199474 0,11115438 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04199474 0,11103224 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04199474 0,11091036 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04199474 0,11078874 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04199474 0,1106674 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04199474 0,11054632 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04199474 0,1104255 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04199474 0,11030495 ! pericardium development GO:0060039 14 7 0,000 0,04199474 0,11018466 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04199474 0,11006464 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04199474 0,10994487 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04199474 0,10982536 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04199474 0,10970612 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04199474 0,10958713 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04199474 0,1094684 ! lipoprotein transport GO:0042953 14 7 0,000 0,04199474 0,10934993 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04199474 0,10923171 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04199474 0,10911375 ! rhythmic behavior GO:0007622 15 7 0,000 0,04199474 0,10899605 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04199474 0,10887859 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04199474 0,10876139 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04199474 0,10864445 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04199474 0,10852775 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04199474 0,1084113 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04199474 0,10829511 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04199474 0,10817916 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04199474 0,10806346 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04199474 0,10794801 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04199474 0,1078328 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04199474 0,10771784 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04199474 0,10760313 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04199474 0,10748865 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04199474 0,10737443 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04199474 0,10726044 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04199474 0,1071467 ! adrenal gland development GO:0030325 17 7 0,000 0,04199474 0,10703319 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04199474 0,10691993 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04199474 0,10680691 ! ovulation GO:0030728 9 7 0,000 0,04199474 0,10669412 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04199474 0,10658158 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04199474 0,10646927 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04199474 0,1063572 ! microtubule nucleation GO:0007020 20 7 0,000 0,04199474 0,10624536 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04199474 0,10613376 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04199474 0,10602239 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04199474 0,10591125 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04199474 0,10580035 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04199474 0,10568968 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04199474 0,10557924 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04199474 0,10546903 ! galactose metabolic process GO:0006012 13 7 0,000 0,04199474 0,10535906 ! vesicle fusion GO:0006906 17 7 0,000 0,04199474 0,10524931 ! response to dietary excess GO:0002021 8 7 0,000 0,04199474 0,10513979 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04199474 0,10503049 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04199474 0,10492143 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04199474 0,10481259 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04199474 0,10470397 ! organ growth GO:0035265 15 7 0,000 0,04199474 0,10459559 ! purine salvage GO:0043101 10 7 0,000 0,04199474 0,10448742 ! nucleoside transport GO:0015858 8 7 0,000 0,04199474 0,10437948 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04199474 0,10427176 ! parturition GO:0007567 14 7 0,000 0,04199474 0,10416426 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04199474 0,10405699 ! rRNA modification GO:0000154 14 7 0,000 0,04199474 0,10394993 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04199474 0,1038431 ! spindle checkpoint GO:0031577 15 7 0,000 0,04199474 0,10373648 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04199474 0,10363009 ! macrophage differentiation GO:0030225 11 7 0,000 0,04199474 0,10352391 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04199474 0,10341795 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04199474 0,1033122 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04199474 0,10320668 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04199474 0,10310136 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04199474 0,10299626 ! fibrinolysis GO:0042730 10 7 0,000 0,04199474 0,10289138 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04199474 0,10278671 ! eating behavior GO:0042755 7 7 0,000 0,04199474 0,10268225 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04199474 0,10257801 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04199474 0,10247397 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04199474 0,10237015 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04199474 0,10226653 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04199474 0,10216313 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04199474 0,10205993 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04199474 0,10195695 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04199474 0,10185417 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04199474 0,1017516 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04199474 0,10164923 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04199474 0,10154707 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04199474 0,10144512 ! regulation of meiosis GO:0040020 12 7 0,000 0,04199474 0,10134337 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04199474 0,10124182 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04199474 0,10114048 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04199474 0,10103934 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04199474 0,1009384 ! transcription termination GO:0006353 13 7 0,000 0,04199474 0,10083766 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04199474 0,10073712 ! anaphase GO:0051322 17 7 0,000 0,04199474 0,10063679 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04199474 0,10053665 ! axonal fasciculation GO:0007413 18 7 0,000 0,04199474 0,10043671 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04199474 0,10033698 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04199474 0,10023744 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04199474 0,10013809 ! diuresis GO:0030146 12 7 0,000 0,04199474 0,10003895 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04199474 0,09994 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04199474 0,09984124 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04199474 0,09974268 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04199474 0,09964431 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04199474 0,09954614 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04199474 0,09944816 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04199474 0,09935038 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04199474 0,09925279 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04199474 0,09915538 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04199474 0,09905817 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04199474 0,09896115 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04199474 0,09886432 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04199474 0,09876768 ! lymph node development GO:0048535 10 7 0,000 0,04199474 0,09867123 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04199474 0,09857496 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04199474 0,09847888 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04199474 0,09838299 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04199474 0,09828729 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04199474 0,09819177 ! adult feeding behavior GO:0008343 9 7 0,000 0,04199474 0,09809644 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04199474 0,0980013 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04199474 0,09790633 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04199474 0,09781155 ! muscle adaptation GO:0043500 14 7 0,000 0,04199474 0,09771696 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04199474 0,09762255 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04199474 0,09752832 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04199474 0,09743427 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04199474 0,0973404 ! protein prenylation GO:0018342 18 7 0,000 0,04199474 0,09724671 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04199474 0,09715321 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04199474 0,09705988 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04199474 0,09696673 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04317829 0,099604 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04317829 0,09950859 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04463175 0,10275981 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04463175 0,10266157 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04610317 0,10594482 ! muscle fiber development GO:0048747 112 57 1,000 0,04759227 0,1092624 ! lipid modification GO:0030258 97 57 1,000 0,04759227 0,10915824 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04759227 0,10905428 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04784904 0,10953833 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04784904 0,1094342 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04784904 0,10933028 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04784904 0,10922655 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04784904 0,10912301 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04784904 0,10901968 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04784904 0,10891654 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04784904 0,10881359 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04784904 0,10871084 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04784904 0,10860828 ! meiotic prophase I GO:0007128 13 8 0,000 0,04784904 0,10850592 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04784904 0,10840375 ! oligopeptide transport GO:0006857 15 8 0,000 0,04784904 0,10830177 ! UTP metabolic process GO:0046051 8 8 0,000 0,04784904 0,10819998 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04784904 0,10809839 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04784904 0,10799698 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04784904 0,10789576 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04784904 0,10779474 ! succinate metabolic process GO:0006105 14 8 0,000 0,04784904 0,1076939 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04784904 0,10759325 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04784904 0,10749279 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04784904 0,10739252 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04784904 0,10729243 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04784904 0,10719253 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04784904 0,10709282 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04784904 0,10699329 ! reflex GO:0060004 16 8 0,000 0,04784904 0,10689395 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04784904 0,10679479 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04784904 0,10669581 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04784904 0,10659702 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04784904 0,10649841 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04784904 0,10639998 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04784904 0,10630174 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04784904 0,10620367 ! pigment granule organization GO:0048753 16 8 0,000 0,04784904 0,10610579 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04784904 0,10600809 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04784904 0,10591056 ! histidine metabolic process GO:0006547 16 8 0,000 0,04784904 0,10581322 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04784904 0,10571605 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04784904 0,10561906 ! glycine catabolic process GO:0006546 13 8 0,000 0,04784904 0,10552226 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04784904 0,10542562 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04784904 0,10532917 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04784904 0,10523289 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04784904 0,10513679 ! melanin metabolic process GO:0006582 15 8 0,000 0,04784904 0,10504086 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04784904 0,10494511 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04784904 0,10484953 ! macrophage activation GO:0042116 12 8 0,000 0,04784904 0,10475412 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04784904 0,10465889 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04784904 0,10456383 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04784904 0,10446895 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04784904 0,10437423 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04784904 0,10427969 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04784904 0,10418532 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04784904 0,10409112 ! osteoblast development GO:0002076 16 8 0,000 0,04784904 0,10399709 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04784904 0,10390323 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04784904 0,10380954 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04784904 0,10371602 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04784904 0,10362266 ! response to UV-B GO:0010224 16 8 0,000 0,04784904 0,10352948 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04784904 0,10343646 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04784904 0,10334361 ! intermediate filament organization GO:0045109 12 8 0,000 0,04784904 0,10325092 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04784904 0,10315841 ! cellular extravasation GO:0045123 12 8 0,000 0,04784904 0,10306605 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04784904 0,10297386 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04784904 0,10288184 ! response to antibiotic GO:0046677 11 8 0,000 0,04784904 0,10278998 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04784904 0,10269829 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04784904 0,10260676 ! response to tropane GO:0014073 15 8 0,000 0,04784904 0,10251539 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04784904 0,10242418 ! melanosome transport GO:0032402 13 8 0,000 0,04784904 0,10233314 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04784904 0,10224226 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04784904 0,10215154 ! mast cell activation GO:0045576 14 8 0,000 0,04784904 0,10206098 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04784904 0,10197058 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04784904 0,10188034 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04784904 0,10179026 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04784904 0,10170034 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04784904 0,10161057 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04784904 0,10152097 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04784904 0,10143152 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04784904 0,10134224 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04784904 0,10125311 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04784904 0,10116413 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04784904 0,10107531 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04784904 0,10098665 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04784904 0,10089814 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04784904 0,10080979 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04784904 0,10072159 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04784904 0,10063355 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04784904 0,10054566 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04784904 0,10045792 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04784904 0,10037034 ! hormone catabolic process GO:0042447 17 8 0,000 0,04784904 0,10028291 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04784904 0,10019563 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04784904 0,1001085 ! ATP catabolic process GO:0006200 11 8 0,000 0,04784904 0,10002153 ! blastocyst growth GO:0001832 19 8 0,000 0,04784904 0,09993471 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04784904 0,09984803 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04784904 0,09976151 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04784904 0,09967513 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04784904 0,09958891 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04784904 0,09950284 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04784904 0,09941691 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04784904 0,09933113 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04784904 0,0992455 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04784904 0,09916002 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04784904 0,09907468 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04784904 0,09898949 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04784904 0,09890445 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04784904 0,09881955 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04784904 0,0987348 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04784904 0,0986502 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04784904 0,09856574 ! regulation of endocytosis GO:0030100 91 58 1,000 0,04909878 0,10105361 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04909878 0,10096724 ! DNA catabolic process GO:0006308 86 59 1,000 0,05062244 0,10401161 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,05062244 0,10392286 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,05062244 0,10383427 ! camera-type eye development GO:0043010 116 60 1,000 0,05216299 0,10690302 ! axon extension GO:0048675 15 9 0,000 0,05366775 0,10989329 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05366775 0,10979984 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05366775 0,10970656 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05366775 0,10961343 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05366775 0,10952045 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05366775 0,10942764 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05366775 0,10933498 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05366775 0,10924248 ! phosphate transport GO:0006817 19 9 0,000 0,05366775 0,10915014 ! reproductive behavior GO:0019098 19 9 0,000 0,05366775 0,10905795 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05366775 0,10896592 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05366775 0,10887404 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05366775 0,10878232 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05366775 0,10869075 ! GTP metabolic process GO:0046039 9 9 0,000 0,05366775 0,10859934 ! RNA methylation GO:0001510 15 9 0,000 0,05366775 0,10850808 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05366775 0,10841697 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05366775 0,10832602 ! artery development GO:0060840 24 9 0,000 0,05366775 0,10823522 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05366775 0,10814457 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05366775 0,10805407 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05366775 0,10796373 ! chemosensory behavior GO:0007635 20 9 0,000 0,05366775 0,10787353 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05366775 0,10778349 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05366775 0,10769359 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05366775 0,10760385 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05366775 0,10751425 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05366775 0,10742481 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05366775 0,10733551 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05366775 0,10724636 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05366775 0,10715736 ! protein targeting to ER GO:0045047 22 9 0,000 0,05366775 0,1070685 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05366775 0,1069798 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05366775 0,10689124 ! T cell selection GO:0045058 23 9 0,000 0,05366775 0,10680283 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05366775 0,10671456 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05366775 0,10662644 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05366775 0,10653846 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05366775 0,10645063 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05366775 0,10636295 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05366775 0,1062754 ! mannose metabolic process GO:0006013 13 9 0,000 0,05366775 0,10618801 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05366775 0,10610075 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05366775 0,10601364 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05366775 0,10592667 ! receptor clustering GO:0043113 18 9 0,000 0,05366775 0,10583985 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05366775 0,10575317 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05366775 0,10566663 ! ruffle organization GO:0031529 15 9 0,000 0,05366775 0,10558023 ! retinol metabolic process GO:0042572 18 9 0,000 0,05366775 0,10549397 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05366775 0,10540785 ! behavioral fear response GO:0001662 22 9 0,000 0,05366775 0,10532187 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05366775 0,10523604 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05366775 0,10515034 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05366775 0,10506478 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05366775 0,10497936 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05366775 0,10489408 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05366775 0,10480894 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05366775 0,10472394 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05366775 0,10463907 ! response to amine stimulus GO:0014075 13 9 0,000 0,05366775 0,10455434 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05366775 0,10446975 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05366775 0,1043853 ! erythrocyte development GO:0048821 15 9 0,000 0,05366775 0,10430098 ! gas homeostasis GO:0033483 16 9 0,000 0,05366775 0,1042168 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05366775 0,10413275 ! renal water homeostasis GO:0003091 14 9 0,000 0,05366775 0,10404884 ! postreplication repair GO:0006301 22 9 0,000 0,05366775 0,10396507 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05366775 0,10388143 ! icosanoid secretion GO:0032309 15 9 0,000 0,05366775 0,10379792 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05366775 0,10371455 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05366775 0,10363131 ! regulation of cell division GO:0051302 15 9 0,000 0,05366775 0,10354821 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05366775 0,10346524 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05366775 0,1033824 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05366775 0,10329969 ! sterol catabolic process GO:0016127 11 9 0,000 0,05366775 0,10321712 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05366775 0,10313468 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05366775 0,10305237 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05366775 0,10297019 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05366775 0,10288814 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05366775 0,10280622 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05366775 0,10272444 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05366775 0,10264278 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05366775 0,10256125 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05366775 0,10247985 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05366775 0,10239859 ! purine base metabolic process GO:0006144 21 9 0,000 0,05366775 0,10231745 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05366775 0,10223643 ! pigment granule transport GO:0051904 17 9 0,000 0,05366775 0,10215555 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05366775 0,1020748 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05366775 0,10199417 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05366775 0,10191367 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05366775 0,10183329 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05366775 0,10175305 ! mitochondrion localization GO:0051646 15 9 0,000 0,05366775 0,10167293 ! mesoderm development GO:0007498 119 61 1,000 0,05372016 0,10169213 ! ear development GO:0043583 103 62 1,000 0,0552937 0,10458855 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0552937 0,10450639 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,05688334 0,10742647 ! detection of external stimulus GO:0009581 91 63 1,000 0,05688334 0,10734222 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05688334 0,10725809 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05848885 0,11019904 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05848885 0,11011281 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0594511 0,11183687 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,0594511 0,1117495 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0594511 0,11166226 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,0594511 0,11157516 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0594511 0,1114882 ! synapsis GO:0007129 13 10 0,000 0,0594511 0,11140137 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0594511 0,11131468 ! N-glycan processing GO:0006491 20 10 0,000 0,0594511 0,11122812 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0594511 0,11114169 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0594511 0,1110554 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0594511 0,11096925 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0594511 0,11088322 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0594511 0,11079733 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0594511 0,11071158 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0594511 0,11062595 ! androgen metabolic process GO:0008209 17 10 0,000 0,0594511 0,11054046 ! phospholipid efflux GO:0033700 16 10 0,000 0,0594511 0,1104551 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0594511 0,11036988 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0594511 0,11028478 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0594511 0,11019981 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0594511 0,11011498 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0594511 0,11003028 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0594511 0,1099457 ! endoderm development GO:0007492 16 10 0,000 0,0594511 0,10986126 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0594511 0,10977694 ! arginine catabolic process GO:0006527 13 10 0,000 0,0594511 0,10969276 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0594511 0,1096087 ! proline metabolic process GO:0006560 13 10 0,000 0,0594511 0,10952478 ! L-serine metabolic process GO:0006563 18 10 0,000 0,0594511 0,10944098 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0594511 0,10935731 ! V(D)J recombination GO:0033151 28 10 0,000 0,0594511 0,10927377 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0594511 0,10919035 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0594511 0,10910706 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0594511 0,1090239 ! B cell proliferation GO:0042100 18 10 0,000 0,0594511 0,10894087 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0594511 0,10885796 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0594511 0,10877518 ! multicellular organism growth GO:0035264 18 10 0,000 0,0594511 0,10869252 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0594511 0,10860999 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0594511 0,10852759 ! epithelial cell development GO:0002064 20 10 0,000 0,0594511 0,10844531 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0594511 0,10836315 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0594511 0,10828112 ! macroautophagy GO:0016236 17 10 0,000 0,0594511 0,10819921 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0594511 0,10811743 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0594511 0,10803577 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0594511 0,10795423 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0594511 0,10787282 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0594511 0,10779153 ! brain morphogenesis GO:0048854 23 10 0,000 0,0594511 0,10771036 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0594511 0,10762931 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0594511 0,10754839 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0594511 0,10746759 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0594511 0,10738691 ! response to dsRNA GO:0043331 20 10 0,000 0,0594511 0,10730635 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0594511 0,10722591 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0594511 0,10714559 ! melanosome localization GO:0032400 16 10 0,000 0,0594511 0,10706539 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0594511 0,10698531 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0594511 0,10690535 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0594511 0,10682551 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0594511 0,10674579 ! mRNA cleavage GO:0006379 17 10 0,000 0,0594511 0,10666619 ! protein sumoylation GO:0016925 15 10 0,000 0,0594511 0,10658671 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0594511 0,10650734 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0594511 0,10642809 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0594511 0,10634897 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0594511 0,10626995 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0594511 0,10619106 ! salivary gland development GO:0007431 27 10 0,000 0,0594511 0,10611228 ! prophase GO:0051324 15 10 0,000 0,0594511 0,10603362 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0594511 0,10595508 ! apical protein localization GO:0045176 15 10 0,000 0,0594511 0,10587665 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0594511 0,10579834 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0594511 0,10572015 ! midbrain development GO:0030901 13 10 0,000 0,0594511 0,10564207 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0594511 0,1055641 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0594511 0,10548625 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0594511 0,10540852 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0594511 0,1053309 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0594511 0,10525339 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0594511 0,105176 ! detection of calcium ion GO:0005513 23 10 0,000 0,0594511 0,10509872 ! oocyte development GO:0048599 17 10 0,000 0,0594511 0,10502156 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0594511 0,1049445 ! blastocyst formation GO:0001825 17 10 0,000 0,0594511 0,10486756 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0594511 0,10479074 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0594511 0,10471403 ! activation of innate immune response GO:0002218 12 10 0,000 0,0594511 0,10463742 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0594511 0,10456093 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0594511 0,10448456 ! response to nicotine GO:0035094 20 10 0,000 0,0594511 0,10440829 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0594511 0,10433214 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0594511 0,10425609 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,06010996 0,10533472 ! developmental maturation GO:0021700 116 66 1,000 0,06174643 0,10812367 ! cell projection assembly GO:0030031 120 66 1,000 0,06174643 0,10804503 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,06339802 0,11085438 ! chromosome segregation GO:0007059 113 67 1,000 0,06339802 0,11077388 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,06339802 0,11069349 ! adaptive immune response GO:0002250 119 67 1,000 0,06339802 0,11061322 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06506447 0,11343849 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06506447 0,11335635 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06506447 0,11327433 ! respiratory burst GO:0045730 17 11 0,000 0,0651993 0,11342699 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0651993 0,11334503 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0651993 0,11326319 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0651993 0,11318147 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0651993 0,11309987 ! thyroid gland development GO:0030878 26 11 0,000 0,0651993 0,11301839 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0651993 0,11293702 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0651993 0,11285577 ! response to pain GO:0048265 24 11 0,000 0,0651993 0,11277464 ! T cell proliferation GO:0042098 26 11 0,000 0,0651993 0,11269362 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0651993 0,11261272 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,0651993 0,11253194 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0651993 0,11245127 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0651993 0,11237072 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0651993 0,11229028 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0651993 0,11220996 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0651993 0,11212975 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0651993 0,11204966 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0651993 0,11196968 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0651993 0,11188982 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0651993 0,11181007 ! UV protection GO:0009650 19 11 0,000 0,0651993 0,11173043 ! adult heart development GO:0007512 14 11 0,000 0,0651993 0,11165091 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0651993 0,1115715 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0651993 0,1114922 ! temperature homeostasis GO:0001659 17 11 0,000 0,0651993 0,11141301 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0651993 0,11133394 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0651993 0,11125498 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0651993 0,11117613 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0651993 0,1110974 ! pigment granule localization GO:0051875 20 11 0,000 0,0651993 0,11101877 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0651993 0,11094026 ! vasoconstriction GO:0042310 18 11 0,000 0,0651993 0,11086185 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0651993 0,11078356 ! embryonic axis specification GO:0000578 18 11 0,000 0,0651993 0,11070538 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0651993 0,11062731 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0651993 0,11054935 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0651993 0,1104715 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0651993 0,11039375 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0651993 0,11031612 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0651993 0,1102386 ! zymogen activation GO:0031638 15 11 0,000 0,0651993 0,11016118 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0651993 0,11008388 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0651993 0,11000668 ! nucleosome positioning GO:0016584 15 11 0,000 0,0651993 0,10992959 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0651993 0,10985261 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0651993 0,10977573 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0651993 0,10969897 ! acid secretion GO:0046717 18 11 0,000 0,0651993 0,10962231 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0651993 0,10954576 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0651993 0,10946931 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0651993 0,10939297 ! oocyte differentiation GO:0009994 18 11 0,000 0,0651993 0,10931674 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0651993 0,10924061 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,0651993 0,10916459 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0651993 0,10908868 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0651993 0,10901287 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0651993 0,10893717 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0651993 0,10886157 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0651993 0,10878608 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0651993 0,10871069 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0651993 0,1086354 ! defense response to fungus GO:0050832 13 11 0,000 0,0651993 0,10856022 ! lysogeny GO:0030069 21 11 0,000 0,0651993 0,10848515 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0651993 0,10841017 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0651993 0,10833531 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0651993 0,10826054 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0651993 0,10818588 ! nucleus localization GO:0051647 19 11 0,000 0,0651993 0,10811132 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0651993 0,10803686 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,06674555 0,11052292 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06674555 0,11044691 ! B cell activation GO:0042113 160 71 1,000 0,07015065 0,1160017 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07091256 0,11718106 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07091256 0,11710063 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07091256 0,11702032 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,07091256 0,11694011 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07091256 0,11686001 ! mating GO:0007618 17 12 0,000 0,07091256 0,11678003 ! protein complex disassembly GO:0043241 27 12 0,000 0,07091256 0,11670015 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07091256 0,11662038 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07091256 0,11654072 ! hippocampus development GO:0021766 26 12 0,000 0,07091256 0,11646117 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07091256 0,11638173 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07091256 0,1163024 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07091256 0,11622317 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07091256 0,11614406 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07091256 0,11606505 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07091256 0,11598615 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07091256 0,11590735 ! drug transport GO:0015893 16 12 0,000 0,07091256 0,11582866 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07091256 0,11575008 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07091256 0,11567161 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07091256 0,11559324 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07091256 0,11551498 ! focal adhesion formation GO:0048041 35 12 0,000 0,07091256 0,11543682 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07091256 0,11535877 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07091256 0,11528082 ! forebrain cell migration GO:0021885 21 12 0,000 0,07091256 0,11520298 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07091256 0,11512525 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07091256 0,11504762 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07091256 0,11497009 ! entry into host cell GO:0030260 32 12 0,000 0,07091256 0,11489267 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07091256 0,11481536 ! monoamine transport GO:0015844 18 12 0,000 0,07091256 0,11473814 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07091256 0,11466104 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07091256 0,11458403 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07091256 0,11450713 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07091256 0,11443033 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07091256 0,11435363 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07091256 0,11427704 ! protein homotetramerization GO:0051289 21 12 0,000 0,07091256 0,11420055 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07091256 0,11412416 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07091256 0,11404787 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07091256 0,11397169 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07091256 0,11389561 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07091256 0,11381963 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07091256 0,11374375 ! fucose catabolic process GO:0019317 22 12 0,000 0,07091256 0,11366797 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07091256 0,11359229 ! histone methylation GO:0016571 26 12 0,000 0,07091256 0,11351671 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07091256 0,11344124 ! gland morphogenesis GO:0022612 29 12 0,000 0,07091256 0,11336586 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07091256 0,11329058 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07091256 0,11321541 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07091256 0,11314033 ! spleen development GO:0048536 22 12 0,000 0,07091256 0,11306535 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07091256 0,11299048 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07091256 0,1129157 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07091256 0,11284102 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07091256 0,11276644 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07091256 0,11269196 ! response to cold GO:0009409 17 12 0,000 0,07091256 0,11261757 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07091256 0,11254329 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0718742 0,11399428 ! carbohydrate transport GO:0008643 110 72 1,000 0,0718742 0,11391918 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,0718742 0,11384419 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,0718742 0,11376929 ! regulation of blood pressure GO:0008217 125 73 1,000 0,07361143 0,11644254 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,07536212 0,11913355 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 1,000 0,07536212 0,11905533 ! eye development GO:0001654 143 74 1,000 0,07536212 0,11897721 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07659109 0,12083814 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07659109 0,12075895 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07659109 0,12067987 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07659109 0,12060089 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07659109 0,12052201 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07659109 0,12044324 ! lipid localization GO:0010876 28 13 0,000 0,07659109 0,12036457 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07659109 0,120286 ! organelle fusion GO:0048284 32 13 0,000 0,07659109 0,12020754 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07659109 0,12012918 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07659109 0,12005092 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07659109 0,11997276 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07659109 0,1198947 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07659109 0,11981675 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07659109 0,11973889 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07659109 0,11966114 ! methionine metabolic process GO:0006555 27 13 0,000 0,07659109 0,11958349 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07659109 0,11950594 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07659109 0,11942849 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07659109 0,11935114 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07659109 0,11927389 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07659109 0,11919674 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07659109 0,11911969 ! exocrine system development GO:0035272 32 13 0,000 0,07659109 0,11904274 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07659109 0,11896589 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07659109 0,11888913 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07659109 0,11881248 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07659109 0,11873593 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07659109 0,11865947 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07659109 0,11858311 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07659109 0,11850685 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07659109 0,11843069 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07659109 0,11835463 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07659109 0,11827866 ! ribosome assembly GO:0042255 17 13 0,000 0,07659109 0,1182028 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07659109 0,11812702 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07659109 0,11805135 ! chromatin silencing GO:0006342 26 13 0,000 0,07659109 0,11797577 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07659109 0,11790029 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07659109 0,11782491 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07659109 0,11774962 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07659109 0,11767443 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07659109 0,11759934 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07659109 0,11752434 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07659109 0,11744943 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07659109 0,11737462 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07659109 0,11729991 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07659109 0,11722529 ! embryonic placenta development GO:0001892 23 13 0,000 0,07659109 0,11715077 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07659109 0,11707634 ! insulin secretion GO:0030073 23 13 0,000 0,07659109 0,11700201 ! actin filament polymerization GO:0030041 24 13 0,000 0,07659109 0,11692777 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07659109 0,11685362 ! acrosome reaction GO:0007340 18 13 0,000 0,07659109 0,11677957 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07712604 0,11752075 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07712604 0,11744637 ! rhythmic process GO:0048511 128 75 1,000 0,07712604 0,11737208 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,07712604 0,11729789 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 0,08069268 0,12264472 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,08069268 0,1225673 ! rRNA transcription GO:0009303 25 14 0,000 0,0822351 0,12483132 ! lactation GO:0007595 26 14 0,000 0,0822351 0,12475261 ! reproductive cellular process GO:0048610 20 14 0,000 0,0822351 0,124674 ! tRNA modification GO:0006400 20 14 0,000 0,0822351 0,12459549 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0822351 0,12451708 ! regulation of S phase GO:0033261 23 14 0,000 0,0822351 0,12443877 ! water transport GO:0006833 21 14 0,000 0,0822351 0,12436056 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0822351 0,12428244 ! non-recombinational repair GO:0000726 25 14 0,000 0,0822351 0,12420442 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0822351 0,1241265 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0822351 0,12404868 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0822351 0,12397095 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0822351 0,12389333 ! palate development GO:0060021 31 14 0,000 0,0822351 0,1238158 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0822351 0,12373836 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0822351 0,12366103 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0822351 0,12358379 ! arginine metabolic process GO:0006525 17 14 0,000 0,0822351 0,12350664 ! regulation of heart rate GO:0002027 24 14 0,000 0,0822351 0,1234296 ! organic alcohol transport GO:0015850 29 14 0,000 0,0822351 0,12335265 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0822351 0,12327579 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0822351 0,12319903 ! L-amino acid transport GO:0015807 30 14 0,000 0,0822351 0,12312237 ! stem cell development GO:0048864 43 14 0,000 0,0822351 0,1230458 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0822351 0,12296933 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0822351 0,12289295 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0822351 0,12281666 ! cerebellum development GO:0021549 21 14 0,000 0,0822351 0,12274047 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0822351 0,12266438 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0822351 0,12258838 ! cofactor transport GO:0051181 26 14 0,000 0,0822351 0,12251247 ! NADP metabolic process GO:0006739 24 14 0,000 0,0822351 0,12243666 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0822351 0,12236094 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0822351 0,12228532 ! intestinal absorption GO:0050892 25 14 0,000 0,0822351 0,12220979 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0822351 0,12213435 ! oxygen transport GO:0015671 21 14 0,000 0,0822351 0,122059 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0822351 0,12198375 ! male genitalia development GO:0030539 24 14 0,000 0,0822351 0,12190859 ! regulation of axon extension GO:0030516 37 14 0,000 0,0822351 0,12183352 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0822351 0,12175855 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,08249496 0,12206819 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,08430958 0,12467661 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,08430958 0,12460003 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,08430958 0,12452354 ! response to metal ion GO:0010038 140 80 1,000 0,08613633 0,12714356 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0878448 0,12958588 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0878448 0,12950648 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0878448 0,12942718 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0878448 0,12934797 ! sulfate transport GO:0008272 23 15 0,000 0,0878448 0,12926885 ! response to cAMP GO:0051591 22 15 0,000 0,0878448 0,12918984 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0878448 0,12911092 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0878448 0,1290321 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0878448 0,12895337 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0878448 0,12887474 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0878448 0,12879621 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0878448 0,12871777 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0878448 0,12863943 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0878448 0,12856118 ! pituitary gland development GO:0021983 29 15 0,000 0,0878448 0,12848303 ! vesicle coating GO:0006901 33 15 0,000 0,0878448 0,12840497 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0878448 0,12832701 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0878448 0,12824914 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0878448 0,12817136 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0878448 0,12809368 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0878448 0,1280161 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0878448 0,12793861 ! histone deacetylation GO:0016575 20 15 0,000 0,0878448 0,12786121 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0878448 0,1277839 ! tissue regeneration GO:0042246 26 15 0,000 0,0878448 0,12770669 ! water homeostasis GO:0030104 27 15 0,000 0,0878448 0,12762958 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0878448 0,12755255 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0878448 0,12747562 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0878448 0,12739878 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0878448 0,12732203 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0878448 0,12724538 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0878448 0,12716882 ! cell killing GO:0001906 29 15 0,000 0,0878448 0,12709235 ! detection of bacterium GO:0016045 18 15 0,000 0,0878448 0,12701597 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0878448 0,12693969 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0878448 0,12686349 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0878448 0,12678739 ! peptide hormone processing GO:0016486 23 15 0,000 0,0878448 0,12671138 ! T cell activation GO:0042110 168 81 1,000 0,08797499 0,12682314 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,08797499 0,1267472 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08797499 0,12667135 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,08797499 0,12659559 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,08797499 0,12651992 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09342039 0,13427088 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09342039 0,13419072 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09342039 0,13411066 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09342039 0,13403069 ! bone remodeling GO:0046849 27 16 0,000 0,09342039 0,13395081 ! filopodium assembly GO:0046847 32 16 0,000 0,09342039 0,13387103 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09342039 0,13379134 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09342039 0,13371175 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09342039 0,13363226 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09342039 0,13355286 ! startle response GO:0001964 28 16 0,000 0,09342039 0,13347355 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09342039 0,13339434 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09342039 0,13331522 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09342039 0,13323619 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09342039 0,13315726 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09342039 0,13307842 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09342039 0,13299968 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09342039 0,13292103 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09342039 0,13284247 ! response to osmotic stress GO:0006970 25 16 0,000 0,09342039 0,132764 ! lysosomal transport GO:0007041 26 16 0,000 0,09342039 0,13268563 ! fructose metabolic process GO:0006000 25 16 0,000 0,09342039 0,13260735 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09342039 0,13252916 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09342039 0,13245107 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09342039 0,13237306 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09342039 0,13229515 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09342039 0,13221733 ! DNA replication initiation GO:0006270 27 16 0,000 0,09342039 0,1321396 ! neuron recognition GO:0008038 35 16 0,000 0,09342039 0,13206196 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09342039 0,13198442 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09342039 0,13190696 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09342039 0,13182959 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09342039 0,13175232 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09342039 0,13167514 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09342039 0,13159804 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09342039 0,13152104 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09342039 0,13144413 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09342039 0,13136731 ! defense response to virus GO:0051607 37 16 0,000 0,09342039 0,13129057 ! negative regulation of transport GO:0051051 153 84 1,000 0,09356036 0,13141052 ! negative regulation of growth GO:0045926 155 84 1,000 0,09356036 0,13133385 ! regulation of ligase activity GO:0051340 142 84 1,000 0,09356036 0,13125727 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,09356036 0,13118078 ! response to inorganic substance GO:0010035 153 86 1,000 0,09733969 0,13640028 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09896209 0,13859301 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09896209 0,13851238 ! metencephalon development GO:0022037 30 17 0,000 0,09896209 0,13843185 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09896209 0,13835141 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,09896209 0,13827107 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09896209 0,13819082 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09896209 0,13811066 ! signal complex assembly GO:0007172 41 17 0,000 0,09896209 0,1380306 ! endothelial cell migration GO:0043542 28 17 0,000 0,09896209 0,13795063 ! inositol metabolic process GO:0006020 28 17 0,000 0,09896209 0,13787075 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09896209 0,13779096 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09896209 0,13771127 ! limbic system development GO:0021761 36 17 0,000 0,09896209 0,13763167 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09896209 0,13755216 ! adult walking behavior GO:0007628 33 17 0,000 0,09896209 0,13747274 ! heart looping GO:0001947 30 17 0,000 0,09896209 0,13739341 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09896209 0,13731418 ! myoblast differentiation GO:0045445 45 17 0,000 0,09896209 0,13723503 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09896209 0,13715598 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09896209 0,13707702 ! glycine metabolic process GO:0006544 28 17 0,000 0,09896209 0,13699815 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09896209 0,13691937 ! NAD metabolic process GO:0019674 29 17 0,000 0,09896209 0,13684068 ! membrane budding GO:0006900 37 17 0,000 0,09896209 0,13676208 ! DNA integration GO:0015074 29 17 0,000 0,09896209 0,13668357 ! regulation of protein binding GO:0043393 33 17 0,000 0,09896209 0,13660515 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09896209 0,13652683 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09896209 0,13644859 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09896209 0,13637044 ! genitalia development GO:0048806 30 17 0,000 0,09896209 0,13629238 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09896209 0,13621441 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09896209 0,13613653 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09896209 0,13605873 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09896209 0,13598103 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09896209 0,13590342 ! steroid catabolic process GO:0006706 31 17 0,000 0,09896209 0,13582589 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09896209 0,13574845 ! gas transport GO:0015669 25 17 0,000 0,09896209 0,1356711 ! organic cation transport GO:0015695 31 17 0,000 0,09896209 0,13559384 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09896209 0,13551667 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09896209 0,13543958 ! microspike assembly GO:0030035 36 17 0,000 0,09896209 0,13536258 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09896209 0,13528567 ! regulation of DNA binding GO:0051101 155 88 1,000 0,10116171 0,13821413 ! regulation of neurological system process GO:0031644 148 88 1,000 0,10116171 0,13813569 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,10308824 0,14068651 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,10308824 0,14060675 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10447009 0,14241079 ! neuron maturation GO:0042551 42 18 0,000 0,10447009 0,14233015 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10447009 0,1422496 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10447009 0,14216914 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10447009 0,14208878 ! memory GO:0007613 31 18 0,000 0,10447009 0,1420085 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10447009 0,14192832 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10447009 0,14184822 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10447009 0,14176822 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10447009 0,1416883 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10447009 0,14160848 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10447009 0,14152874 ! response to retinoic acid GO:0032526 26 18 0,000 0,10447009 0,1414491 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,10447009 0,14136954 ! response to fungus GO:0009620 21 18 0,000 0,10447009 0,14129008 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10447009 0,1412107 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10447009 0,14113141 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10447009 0,14105221 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10447009 0,1409731 ! vitamin transport GO:0051180 27 18 0,000 0,10447009 0,14089408 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10447009 0,14081515 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10447009 0,14073631 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10447009 0,14065755 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10447009 0,14057888 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,10447009 0,14050031 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10447009 0,14042181 ! protein secretion GO:0009306 39 19 0,000 0,10994461 0,14769779 ! positive regulation of translation GO:0045727 30 19 0,000 0,10994461 0,14761537 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10994461 0,14753304 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10994461 0,1474508 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10994461 0,14736865 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10994461 0,1472866 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10994461 0,14720464 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10994461 0,14712277 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10994461 0,14704099 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10994461 0,1469593 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10994461 0,1468777 ! cerebral cortex development GO:0021987 36 19 0,000 0,10994461 0,14679619 ! pigmentation during development GO:0048066 41 19 0,000 0,10994461 0,14671477 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10994461 0,14663345 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10994461 0,14655221 ! heme metabolic process GO:0042168 36 19 0,000 0,10994461 0,14647106 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10994461 0,14639 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10994461 0,14630904 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10994461 0,14622816 ! peptide cross-linking GO:0018149 37 19 0,000 0,10994461 0,14614737 ! protein export from nucleus GO:0006611 36 19 0,000 0,10994461 0,14606667 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10994461 0,14598606 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,10994461 0,14590554 ! cellular pigmentation GO:0033059 36 19 0,000 0,10994461 0,1458251 ! G1 phase GO:0051318 40 19 0,000 0,10994461 0,14574476 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10994461 0,1456645 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10994461 0,14558433 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10994461 0,14550425 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10994461 0,14542426 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10994461 0,14534436 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10994461 0,14526454 ! cilium assembly GO:0042384 37 19 0,000 0,10994461 0,14518482 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10994461 0,14510518 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,11089327 0,14627698 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,11089327 0,14619683 ! female pregnancy GO:0007565 164 94 1,000 0,1128683 0,14871913 ! forebrain development GO:0030900 188 95 1,000 0,11485247 0,1512507 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,11485247 0,15116796 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11538584 0,15178695 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11538584 0,15170401 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11538584 0,15162116 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11538584 0,15153839 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11538584 0,15145572 ! response to vitamin GO:0033273 31 20 0,000 0,11538584 0,15137314 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11538584 0,15129065 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11538584 0,15120825 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11538584 0,15112593 ! response to alkaloid GO:0043279 38 20 0,000 0,11538584 0,15104371 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11538584 0,15096158 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11538584 0,15087953 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11538584 0,15079758 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11538584 0,15071571 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11538584 0,15063393 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11538584 0,15055224 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11538584 0,15047064 ! body fluid secretion GO:0007589 31 20 0,000 0,11538584 0,15038913 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11538584 0,15030771 ! peptide secretion GO:0002790 35 20 0,000 0,11538584 0,15022637 ! stem cell differentiation GO:0048863 53 20 0,000 0,11538584 0,15014513 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11538584 0,15006397 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11538584 0,1499829 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11538584 0,14990191 ! sensory perception of pain GO:0019233 30 20 0,000 0,11538584 0,14982101 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11538584 0,1497402 ! diencephalon development GO:0021536 34 20 0,000 0,11538584 0,14965948 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11538584 0,14957885 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11538584 0,1494983 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11538584 0,14941784 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11538584 0,14933746 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11538584 0,14925717 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11538584 0,14917697 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11538584 0,14909685 ! regulation of glucose import GO:0046324 29 20 0,000 0,11538584 0,14901682 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11538584 0,14893688 ! actin filament-based movement GO:0030048 43 20 0,000 0,11538584 0,14885702 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11538584 0,14877724 ! negative regulation of translation GO:0017148 29 20 0,000 0,11538584 0,14869756 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11538584 0,14861795 ! leukocyte differentiation GO:0002521 202 96 1,000 0,11684559 0,15041759 ! mRNA transport GO:0051028 169 96 1,000 0,11684559 0,15033715 ! detection of stimulus GO:0051606 151 96 1,000 0,11684559 0,1502568 ! regulation of cell killing GO:0031341 42 21 0,000 0,12079399 0,15525125 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12079399 0,15516836 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12079399 0,15508556 ! hormone secretion GO:0046879 38 21 0,000 0,12079399 0,15500285 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12079399 0,15492022 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12079399 0,15483769 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12079399 0,15475524 ! axis specification GO:0009798 38 21 0,000 0,12079399 0,15467288 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,12079399 0,15459061 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12079399 0,15450842 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12079399 0,15442632 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12079399 0,15434431 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12079399 0,15426239 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12079399 0,15418055 ! cytolysis GO:0019835 24 21 0,000 0,12079399 0,1540988 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12079399 0,15401714 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12079399 0,15393556 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12079399 0,15385407 ! oogenesis GO:0048477 36 21 0,000 0,12079399 0,15377267 ! DNA modification GO:0006304 34 21 0,000 0,12079399 0,15369135 ! collagen fibril organization GO:0030199 59 21 0,000 0,12079399 0,15361012 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12079399 0,15352897 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12079399 0,15344791 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,12079399 0,15336693 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12079399 0,15328604 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12079399 0,15320524 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12079399 0,15312452 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12079399 0,15304389 ! collagen catabolic process GO:0030574 28 21 0,000 0,12079399 0,15296334 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12079399 0,15288287 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,12287684 0,15543726 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12616925 0,15951825 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12616925 0,15943447 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12616925 0,15935077 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12616925 0,15926717 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12616925 0,15918365 ! regeneration GO:0031099 41 22 0,000 0,12616925 0,15910022 ! keratinization GO:0031424 28 22 0,000 0,12616925 0,15901688 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12616925 0,15893362 ! sensory perception of taste GO:0050909 28 22 0,000 0,12616925 0,15885046 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12616925 0,15876738 ! vacuolar transport GO:0007034 36 22 0,000 0,12616925 0,15868438 ! lysosome organization GO:0007040 41 22 0,000 0,12616925 0,15860147 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12616925 0,15851865 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12616925 0,15843592 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12616925 0,15835327 ! fucose metabolic process GO:0006004 39 22 0,000 0,12616925 0,15827071 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12616925 0,15818823 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12616925 0,15810585 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12616925 0,15802354 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12616925 0,15794132 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12616925 0,15785919 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12616925 0,15777714 ! sarcomere organization GO:0045214 30 22 0,000 0,12616925 0,15769518 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,12616925 0,1576133 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12616925 0,15753151 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12616925 0,1574498 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12616925 0,15736818 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,12616925 0,15728664 ! protein stabilization GO:0050821 39 22 0,000 0,12616925 0,15720519 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13151183 0,16377715 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,13151183 0,16369243 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13151183 0,16360779 ! gluconeogenesis GO:0006094 33 23 0,000 0,13151183 0,16352324 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13151183 0,16343877 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13151183 0,1633544 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13151183 0,1632701 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13151183 0,1631859 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13151183 0,16310179 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13151183 0,16301776 ! visual behavior GO:0007632 42 23 0,000 0,13151183 0,16293381 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,13151183 0,16284996 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13151183 0,16276618 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13151183 0,1626825 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13151183 0,1625989 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13151183 0,16251539 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13151183 0,16243196 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13151183 0,16234862 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13151183 0,16226537 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13151183 0,1621822 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13151183 0,16209911 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13151183 0,16201611 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13151183 0,1619332 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13151183 0,16185036 ! fatty acid transport GO:0015908 44 23 0,000 0,13151183 0,16176762 ! platelet activation GO:0030168 37 23 0,000 0,13151183 0,16168496 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13151183 0,16160238 ! hormone transport GO:0009914 40 23 0,000 0,13151183 0,16151989 ! cell-cell recognition GO:0009988 25 23 0,000 0,13151183 0,16143748 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13151183 0,16135516 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13151183 0,16127292 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13151183 0,16119076 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13151183 0,16110869 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13682192 0,16752852 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13682192 0,16744331 ! vesicle docking GO:0048278 47 24 0,000 0,13682192 0,16735818 ! vacuole organization GO:0007033 43 24 0,000 0,13682192 0,16727314 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13682192 0,16718819 ! digestive system process GO:0022600 39 24 0,000 0,13682192 0,16710332 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13682192 0,16701854 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13682192 0,16693384 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13682192 0,16684923 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13682192 0,16676471 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13682192 0,16668027 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,13682192 0,16659592 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13682192 0,16651165 ! membrane depolarization GO:0051899 39 24 0,000 0,13682192 0,16642747 ! pallium development GO:0021543 49 24 0,000 0,13682192 0,16634337 ! pentose metabolic process GO:0019321 35 24 0,000 0,13682192 0,16625936 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13682192 0,16617544 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13682192 0,16609159 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13682192 0,16600784 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13682192 0,16592416 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13682192 0,16584057 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13682192 0,16575707 ! regulation of amine transport GO:0051952 40 24 0,000 0,13682192 0,16567365 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14209972 0,17197783 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,14209972 0,17189136 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14209972 0,17180498 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,14209972 0,17171869 ! phototransduction GO:0007602 33 25 0,000 0,14209972 0,17163249 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14209972 0,17154637 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,14209972 0,17146034 ! receptor metabolic process GO:0043112 46 25 0,000 0,14209972 0,1713744 ! neural crest cell development GO:0014032 54 25 0,000 0,14209972 0,17128854 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14209972 0,17120276 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14209972 0,17111708 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14209972 0,17103148 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,14209972 0,17094596 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14209972 0,17086053 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14209972 0,17077518 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14209972 0,17068992 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14209972 0,17060475 ! telomere organization GO:0032200 43 25 0,000 0,14209972 0,17051966 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,14209972 0,17043466 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14734542 0,1766383 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14734542 0,17655034 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14734542 0,17646246 ! initiation of viral infection GO:0019059 57 26 0,000 0,14734542 0,17637467 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14734542 0,17628696 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14734542 0,17619934 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14734542 0,17611181 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14734542 0,17602437 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,14734542 0,17593701 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14734542 0,17584974 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,14734542 0,17576256 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14734542 0,17567546 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,14734542 0,17558845 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14734542 0,17550152 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14734542 0,17541468 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14734542 0,17532793 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,14734542 0,17524126 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14734542 0,17515468 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14734542 0,17506819 ! blastocyst development GO:0001824 49 26 0,000 0,14734542 0,17498178 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14734542 0,17489545 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14734542 0,17480921 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14734542 0,17472305 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15255922 0,18081649 ! iron ion transport GO:0006826 59 27 0,000 0,15255922 0,18072746 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15255922 0,18063852 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15255922 0,18054967 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! fat cell differentiation GO:0045444 50 27 0,000 0,15255922 0,1804609 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15255922 0,18037223 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15255922 0,18028363 ! autophagy GO:0006914 41 27 0,000 0,15255922 0,18019513 ! male gonad development GO:0008584 44 27 0,000 0,15255922 0,18010671 ! response to toxin GO:0009636 47 27 0,000 0,15255922 0,18001838 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15255922 0,17993014 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15255922 0,17984198 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,15255922 0,17975391 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15255922 0,17966592 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15255922 0,17957802 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15255922 0,17949021 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15774131 0,18549638 ! circadian rhythm GO:0007623 50 28 0,000 0,15774131 0,18540576 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15774131 0,18531523 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15774131 0,18522479 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15774131 0,18513443 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15774131 0,18504417 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15774131 0,18495399 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15774131 0,1848639 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15774131 0,1847739 ! lipid oxidation GO:0034440 43 28 0,000 0,15774131 0,18468398 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15774131 0,18459416 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15774131 0,18450442 ! translational initiation GO:0006413 65 29 0,000 0,16289188 0,19043628 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,16289188 0,19034379 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,16289188 0,19025139 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16289188 0,19015908 ! catechol metabolic process GO:0009712 54 29 0,000 0,16289188 0,19006686 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16289188 0,18997473 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16289188 0,18988269 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16289188 0,18979074 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16289188 0,18969887 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,16289188 0,1896071 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,16289188 0,18951541 ! cell fate determination GO:0001709 60 29 0,000 0,16289188 0,18942381 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16289188 0,1893323 ! detection of light stimulus GO:0009583 38 29 0,000 0,16289188 0,18924088 ! regulation of coagulation GO:0050818 46 29 0,000 0,16289188 0,18914955 ! phenol metabolic process GO:0018958 55 30 0,000 0,16801113 0,19499989 ! zinc ion transport GO:0006829 45 30 0,000 0,16801113 0,19490587 ! membrane docking GO:0022406 61 30 0,000 0,16801113 0,19481194 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16801113 0,1947181 ! cell junction assembly GO:0034329 78 30 0,000 0,16801113 0,19462435 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16801113 0,19453069 ! acute-phase response GO:0006953 49 30 0,000 0,16801113 0,19443712 ! myofibril assembly GO:0030239 47 30 0,000 0,16801113 0,19434364 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16801113 0,19425025 ! phospholipid transport GO:0015914 51 30 0,000 0,16801113 0,19415695 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16801113 0,19406374 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16801113 0,19397062 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16801113 0,19387759 ! regulation of B cell activation GO:0050864 50 30 0,000 0,16801113 0,19378465 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17309924 0,19955763 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17309924 0,19946205 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17309924 0,19936657 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17309924 0,19927118 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,17309924 0,19917588 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17309924 0,19908067 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17309924 0,19898556 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17309924 0,19889053 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17309924 0,19879559 ! peptide transport GO:0015833 55 31 0,000 0,17309924 0,19870075 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17309924 0,19860599 ! mesoderm formation GO:0001707 69 31 0,000 0,17309924 0,19851133 ! natural killer cell activation GO:0030101 45 31 0,000 0,17309924 0,19841675 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17309924 0,19832227 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17309924 0,19822788 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17309924 0,19813357 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,17309924 0,19803936 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17309924 0,19794523 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1781564 0,20363149 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1781564 0,2035348 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1781564 0,2034382 ! cholesterol transport GO:0030301 56 32 0,000 0,1781564 0,2033417 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1781564 0,20324528 ! spliceosome assembly GO:0000245 67 32 0,000 0,1781564 0,20314896 ! spindle organization GO:0007051 46 32 0,000 0,1781564 0,20305272 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1781564 0,20295658 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1781564 0,20286053 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1781564 0,20276457 ! muscle cell development GO:0055001 49 32 0,000 0,1781564 0,2026687 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1781564 0,20257292 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1781564 0,20247723 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1781564 0,20238163 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,1781564 0,20228612 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1781564 0,20219071 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1781564 0,20209538 ! gene silencing GO:0016458 65 32 0,000 0,1781564 0,20200014 ! post-embryonic development GO:0009791 69 33 0,000 0,1831828 0,20760142 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1831828 0,20750368 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1831828 0,20740603 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1831828 0,20730847 ! sterol transport GO:0015918 57 33 0,000 0,1831828 0,20721101 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,1831828 0,20711363 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1831828 0,20701635 ! adult locomotory behavior GO:0008344 59 33 0,000 0,1831828 0,20691916 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,1831828 0,20682206 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18817862 0,21236293 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18817862 0,21226337 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18817862 0,2121639 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18817862 0,21206453 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,18817862 0,21196525 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18817862 0,21186606 ! mismatch repair GO:0006298 46 34 0,000 0,18817862 0,21176696 ! spermatid development GO:0007286 63 34 0,000 0,18817862 0,21166796 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18817862 0,21156905 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18817862 0,21147023 ! negative regulation of secretion GO:0051048 63 35 0,000 0,19314406 0,21694893 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,19314406 0,21684769 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19314406 0,21674655 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,19314406 0,2166455 ! vesicle localization GO:0051648 64 35 0,000 0,19314406 0,21654455 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,19807928 0,22197427 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,19807928 0,22187093 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19807928 0,22176768 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19807928 0,22166454 ! cell junction organization GO:0034330 86 36 0,000 0,19807928 0,22156148 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19807928 0,22145853 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,19807928 0,22135567 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19807928 0,2212529 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19807928 0,22115023 ! aerobic respiration GO:0009060 55 36 0,000 0,19807928 0,22104766 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19807928 0,22094518 ! RNA export from nucleus GO:0006405 56 37 0,000 0,20298449 0,22631171 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,20298449 0,22620689 ! meiosis I GO:0007127 65 37 0,000 0,20298449 0,22610216 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,20298449 0,22599753 ! sister chromatid segregation GO:0000819 58 37 0,000 0,20298449 0,225893 ! actomyosin structure organization GO:0031032 62 37 0,000 0,20298449 0,22578857 ! organic anion transport GO:0015711 68 37 0,000 0,20298449 0,22568423 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,20298449 0,22557999 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20298449 0,22547584 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20298449 0,22537179 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20298449 0,22526784 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,20298449 0,22516398 ! pigment metabolic process GO:0042440 80 37 0,000 0,20298449 0,22506022 ! spermatid differentiation GO:0048515 66 37 0,000 0,20298449 0,22495655 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20785985 0,23025359 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20785985 0,23014763 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20785985 0,23004176 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20785985 0,229936 ! lipid homeostasis GO:0055088 67 38 0,000 0,20785985 0,22983033 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20785985 0,22972475 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20785985 0,22961928 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,20785985 0,2295139 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20785985 0,22940862 ! mRNA catabolic process GO:0006402 71 39 0,000 0,21270555 0,23464903 ! learning GO:0007612 77 39 0,000 0,21270555 0,2345415 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21270555 0,23443406 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,21270555 0,23432671 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21270555 0,23421947 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,21270555 0,23411233 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,21270555 0,23400528 ! RNA modification GO:0009451 57 39 0,000 0,21270555 0,23389833 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21270555 0,23379148 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21752176 0,23897596 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21752176 0,23886689 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21752176 0,23875792 ! feeding behavior GO:0007631 59 40 0,000 0,21752176 0,23864905 ! negative regulation of binding GO:0051100 72 40 0,000 0,21752176 0,23854027 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,21752176 0,2384316 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21752176 0,23832302 ! maintenance of protein location GO:0045185 91 40 0,000 0,21752176 0,23821455 ! cytokinesis GO:0000910 72 40 0,000 0,21752176 0,23810617 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,22230868 0,24323541 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,22230868 0,24312485 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,22230868 0,24301439 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,22230868 0,24290403 ! female gamete generation GO:0007292 61 41 0,000 0,22230868 0,24279377 ! polyol metabolic process GO:0019751 66 41 0,000 0,22230868 0,24268361 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22706646 0,24776504 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22706646 0,24765272 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22706646 0,24754051 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22706646 0,2474284 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,2317953 0,25246695 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,2317953 0,25235271 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,2317953 0,25223858 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,2317953 0,25212454 ! phagocytosis GO:0006909 90 43 0,000 0,2317953 0,25201062 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,2317953 0,25189679 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23649536 0,25688842 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23649536 0,25677249 ! biopolymer methylation GO:0043414 84 44 0,000 0,23649536 0,25665667 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23649536 0,25654096 ! maintenance of location in cell GO:0051651 97 44 0,000 0,23649536 0,25642535 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,24116682 0,26137269 ! glycolysis GO:0006096 65 45 0,000 0,24116682 0,26125501 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,24116682 0,26113743 ! leukocyte migration GO:0050900 68 45 0,000 0,24116682 0,26101996 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,24116682 0,2609026 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,24116682 0,26078534 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,24116682 0,26066818 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,24116682 0,26055113 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,24116682 0,26043419 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24580986 0,26532908 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,24580986 0,2652101 ! pigmentation GO:0043473 100 46 0,000 0,24580986 0,26509122 ! positive regulation of defense response GO:0031349 76 47 0,000 0,25042463 0,26994699 ! response to calcium ion GO:0051592 81 47 0,000 0,25042463 0,2698261 ! endosome transport GO:0016197 108 47 0,000 0,25042463 0,26970531 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,25042463 0,26958464 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,25042463 0,26946407 ! JNK cascade GO:0007254 91 47 0,000 0,25042463 0,26934362 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,25042463 0,26922327 ! methylation GO:0032259 90 47 0,000 0,25042463 0,26910302 ! protein homooligomerization GO:0051260 76 47 0,000 0,25042463 0,26898289 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25501133 0,27378726 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,25501133 0,27366515 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25501133 0,27354314 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25501133 0,27342124 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,25501133 0,27329945 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25957011 0,2780613 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25957011 0,27793755 ! regulation of ion transport GO:0043269 77 49 0,000 0,25957011 0,27781391 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,25957011 0,27769039 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25957011 0,27756697 ! endocrine system development GO:0035270 104 49 0,000 0,25957011 0,27744366 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25957011 0,27732046 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25957011 0,27719737 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25957011 0,27707439 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,26410114 0,28178596 ! neuromuscular process GO:0050905 99 50 0,000 0,26410114 0,28166106 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,2686046 0,28633702 ! excretion GO:0007588 83 51 0,000 0,2686046 0,28621021 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,2686046 0,28608351 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,2686046 0,28595693 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,2686046 0,28583045 ! vesicle organization GO:0016050 107 51 0,000 0,2686046 0,28570409 ! membrane fusion GO:0006944 110 52 0,000 0,27308064 0,29033673 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,27752944 0,29493632 ! RNA catabolic process GO:0006401 93 53 0,000 0,27752944 0,29480611 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27752944 0,29467601 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,27752944 0,29454602 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27752944 0,29441615 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,27752944 0,2942864 ! cell maturation GO:0048469 100 53 0,000 0,27752944 0,29415675 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27752944 0,29402723 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,28195116 0,29858032 ! cell recognition GO:0008037 85 54 0,000 0,28195116 0,29844896 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,28195116 0,29831772 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,28195116 0,29818659 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,28195116 0,29805557 ! chloride transport GO:0006821 90 55 0,000 0,28634596 0,30256846 ! glucose catabolic process GO:0006007 82 55 0,000 0,28634596 0,30243564 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,28634596 0,30230293 ! gastrulation GO:0007369 112 55 0,000 0,28634596 0,30217035 ! RNA elongation GO:0006354 79 55 0,000 0,28634596 0,30203787 ! nuclear export GO:0051168 97 55 0,000 0,28634596 0,30190552 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,28634596 0,30177327 ! regulation of actin filament length GO:0030832 105 56 0,000 0,29071401 0,30624252 ! sensory perception of smell GO:0007608 80 56 0,000 0,29071401 0,3061085 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,29071401 0,30597459 ! proton transport GO:0015992 94 56 0,000 0,29071401 0,3058408 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,29071401 0,30570713 ! maintenance of location GO:0051235 118 57 0,000 0,29505547 0,31013695 ! hydrogen transport GO:0006818 97 58 0,000 0,2993705 0,31453512 ! adult behavior GO:0030534 99 58 0,000 0,2993705 0,31439783 ! positive regulation of secretion GO:0051047 95 59 0,000 0,30365926 0,31876273 ! regulation of cellular component size GO:0032535 109 59 0,000 0,30365926 0,31862372 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,30365926 0,31848482 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,30365926 0,31834605 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,30792191 0,32267427 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30792191 0,32253379 ! regulation of heart contraction GO:0008016 110 60 0,000 0,30792191 0,32239344 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,30792191 0,32225321 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,31215861 0,32654505 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,31215861 0,32640313 ! tRNA processing GO:0008033 89 61 0,000 0,31215861 0,32626134 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,31215861 0,32611967 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,31636951 0,33037545 ! regulation of mitosis GO:0007088 105 63 0,000 0,32055477 0,33460077 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,32055477 0,33445567 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,32055477 0,33431069 ! cell redox homeostasis GO:0045454 102 64 0,000 0,32471454 0,33850225 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,32471454 0,33835565 ! single fertilization GO:0007338 75 64 0,000 0,32471454 0,33820918 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32884899 0,34236723 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,32884899 0,34221915 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,33295826 0,34634569 ! actin filament organization GO:0007015 148 66 0,000 0,33295826 0,34619601 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,33295826 0,34604647 ! extracellular matrix organization GO:0030198 133 66 0,000 0,33295826 0,34589705 ! secondary metabolic process GO:0019748 116 66 0,000 0,33295826 0,34574777 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,33704251 0,34983791 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,33704251 0,34968705 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,33704251 0,34953632 ! hexose catabolic process GO:0019320 104 67 0,000 0,33704251 0,34938573 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,33704251 0,34923526 ! activation of immune response GO:0002253 105 67 0,000 0,33704251 0,34908492 ! amino acid transport GO:0006865 125 68 0,000 0,34110188 0,35313732 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,34110188 0,35298543 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,34110188 0,35283367 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,34110188 0,35268205 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,34513653 0,35670039 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,34513653 0,35654723 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,34513653 0,35639421 ! antigen processing and presentation GO:0019882 104 69 0,000 0,34513653 0,35624131 ! amine catabolic process GO:0009310 117 71 0,000 0,35313227 0,36433801 ! humoral immune response GO:0006959 109 71 0,000 0,35313227 0,36418184 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,35313227 0,36402581 ! regulation of immune effector process GO:0002697 137 71 0,000 0,35313227 0,36386991 ! acute inflammatory response GO:0002526 113 72 0,000 0,35709365 0,36779423 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,35709365 0,36763685 ! learning or memory GO:0007611 147 73 0,000 0,3610309 0,37153138 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,3610309 0,37137253 ! fertilization GO:0009566 90 73 0,000 0,3610309 0,37121383 ! neurotransmitter transport GO:0006836 123 74 0,000 0,36494417 0,37507718 ! meiosis GO:0007126 121 74 0,000 0,36494417 0,37491703 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,36494417 0,37475701 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,36494417 0,37459714 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,36494417 0,37443739 ! organelle localization GO:0051640 136 74 0,000 0,36494417 0,37427779 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36883361 0,37810552 ! meiotic cell cycle GO:0051321 122 75 0,000 0,36883361 0,37794449 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,37269935 0,38174314 ! defense response to bacterium GO:0042742 89 76 0,000 0,37269935 0,3815807 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,37269935 0,38141839 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,37269935 0,38125622 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,37654154 0,38502293 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,37654154 0,38485937 ! blood coagulation GO:0007596 146 78 0,000 0,38036033 0,38859743 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,38036033 0,38843249 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,38036033 0,38826769 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,38415585 0,39197582 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,38415585 0,39180966 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,38792825 0,39548957 ! muscle cell differentiation GO:0042692 159 80 0,000 0,38792825 0,39532206 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,38792825 0,39515469 ! inorganic anion transport GO:0015698 138 80 0,000 0,38792825 0,39498746 ! digestion GO:0007586 112 81 0,000 0,39167767 0,39863641 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,39540424 0,40225903 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,39540424 0,40208901 ! response to nutrient GO:0007584 125 82 0,000 0,39540424 0,40191914 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,39540424 0,40174941 ! regulation of lyase activity GO:0051339 160 83 0,000 0,39910811 0,40534154 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,4027894 0,40890772 ! hemostasis GO:0007599 158 84 0,000 0,4027894 0,40873526 ! response to unfolded protein GO:0006986 131 85 0,000 0,40644827 0,41227426 ! nucleosome assembly GO:0006334 122 85 0,000 0,40644827 0,41210052 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,40644827 0,41192693 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,40644827 0,41175349 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 0,000 0,41008484 0,41526268 ! chromatin assembly GO:0031497 124 86 0,000 0,41008484 0,41508798 ! alcohol catabolic process GO:0046164 130 86 0,000 0,41008484 0,41491343 ! amine transport GO:0015837 155 86 0,000 0,41008484 0,41473902 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,41369925 0,41821866 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,41369925 0,41804301 ! cellular respiration GO:0045333 135 88 0,000 0,41729164 0,42149609 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,41729164 0,42131921 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,41729164 0,42114249 ! cellular defense response GO:0006968 114 89 0,000 0,42086213 0,42456784 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,42441087 0,42796838 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,42441087 0,42778908 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,42441087 0,42760994 ! sterol metabolic process GO:0016125 152 91 0,000 0,42793797 0,43098316 ! response to protein stimulus GO:0051789 149 91 0,000 0,42793797 0,43080283 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,42793797 0,43062265 ! regulation of defense response GO:0031347 149 92 0,000 0,43144358 0,43396875 ! nucleosome organization GO:0034728 138 92 0,000 0,43144358 0,4337874 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,43144358 0,43360621 ! vitamin metabolic process GO:0006766 139 92 0,000 0,43144358 0,43342516 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,43492782 0,43674305 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,43839083 0,44003685 ! transcription initiation GO:0006352 153 94 0,000 0,43839083 0,43985335 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,44525364 0,44655284 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,44525364 0,44636678 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,44865371 0,44958801 ! hormone metabolic process GO:0042445 157 97 0,000 0,44865371 0,44940084 ! response to virus GO:0009615 160 98 0,000 0,45203305 0,45259738 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,45203305 0,45240911 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,45203305 0,452221 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,45539178 0,45539178