pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6287-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 9,000 9,16E-13 2,204E-09 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 1,989E-10 2,393E-07 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 4,000 2,501E-09 2,006E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of phosphorylation GO:0042326 47 24 5,000 3,794E-09 2,282E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 3,838E-09 1,847E-06 ! negative regulation of protein kinase activity GO:0006469 130 67 7,000 4,494E-09 1,802E-06 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 4,995E-09 1,717E-06 ! spindle assembly GO:0051225 6 5 3,000 4,995E-09 1,502E-06 ! interphase GO:0051325 213 98 8,000 5,066E-09 1,354E-06 ! negative regulation of kinase activity GO:0033673 131 68 7,000 5,069E-09 1,22E-06 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 6,428E-09 1,406E-06 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of transferase activity GO:0051348 140 72 7,000 8,05E-09 1,614E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,492E-08 2,761E-06 ! spindle organization GO:0007051 46 32 5,000 2,46E-08 4,228E-06 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 3,258E-08 5,227E-06 ! regulation of protein export from nucleus GO:0046825 10 7 3,000 3,465E-08 5,211E-06 ! organ growth GO:0035265 15 7 3,000 3,465E-08 4,905E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 3,465E-08 4,632E-06 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 3,465E-08 4,388E-06 ! regulation of protein stability GO:0031647 73 37 5,000 6,164E-08 7,416E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 6,9E-08 7,906E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 6,9E-08 7,546E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 1,237E-07 1,294E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 4,000 1,724E-07 1,728E-05 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 2,052E-07 1,975E-05 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 2,052E-07 1,899E-05 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 2,052E-07 1,828E-05 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of B cell proliferation GO:0030888 20 12 3,000 4,793E-07 4,119E-05 ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 4,793E-07 3,977E-05 ! negative regulation of transport GO:0051051 153 84 6,000 5,274E-07 4,23E-05 ! cellular response to extracellular stimulus GO:0031668 48 29 4,000 5,918E-07 4,593E-05 ! response to heat GO:0009408 50 30 4,000 7,069E-07 5,315E-05 ! cell killing GO:0001906 29 15 3,000 1,304E-06 9,51E-05 ! negative regulation of cell adhesion GO:0007162 81 35 4,000 1,574E-06 1,114E-04 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 2,254E-06 1,55E-04 ! endothelial cell migration GO:0043542 28 17 3,000 2,254E-06 1,507E-04 ! inositol metabolic process GO:0006020 28 17 3,000 2,254E-06 1,466E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 2,254E-06 1,427E-04 ! cell cycle checkpoint GO:0000075 137 69 5,000 2,735E-06 1,688E-04 ! negative regulation of B cell activation GO:0050869 13 6 2,000 3,552E-06 2,137E-04 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 3,639E-06 2,135E-04 ! regulation of intracellular protein transport GO:0033157 80 42 4,000 3,993E-06 2,288E-04 ! cellular response to starvation GO:0009267 33 20 3,000 4,528E-06 2,534E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 5,657E-06 3,093E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 6,191E-06 3,31E-04 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 6,318E-06 3,305E-04 ! negative regulation of cell migration GO:0030336 115 46 4,000 6,318E-06 3,234E-04 ! response to temperature stimulus GO:0009266 76 49 4,000 8,669E-06 4,345E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 9,863E-06 4,843E-04 ! response to starvation GO:0042594 42 25 3,000 1,156E-05 5,564E-04 ! regulation of insulin secretion GO:0050796 37 25 3,000 1,156E-05 5,455E-04 ! cellular response to nutrient levels GO:0031669 41 25 3,000 1,156E-05 5,35E-04 ! response to UV GO:0009411 104 53 4,000 1,281E-05 5,815E-04 ! autophagic vacuole formation GO:0000045 15 9 2,000 1,473E-05 6,565E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,473E-05 6,445E-04 ! negative regulation of cell motion GO:0051271 134 55 4,000 1,539E-05 6,611E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 1,554E-05 6,561E-04 ! lipid modification GO:0030258 97 57 4,000 1,835E-05 7,612E-04 ! regulation of intracellular transport GO:0032386 101 57 4,000 1,835E-05 7,483E-04 ! macroautophagy GO:0016236 17 10 2,000 2,096E-05 8,405E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,096E-05 8,267E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 2,133E-05 8,277E-04 ! cell junction assembly GO:0034329 78 30 3,000 2,45E-05 9,357E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 2,45E-05 9,211E-04 ! regulation of B cell activation GO:0050864 50 30 3,000 2,45E-05 9,07E-04 ! triglyceride metabolic process GO:0006641 43 31 3,000 2,801E-05 1,021E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 3,000 2,801E-05 1,006E-03 GO:0043433|negative regulation of transcription factor activity, ! chondrocyte differentiation GO:0002062 24 11 2,000 2,87E-05 1,015E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,87E-05 1,001E-03 GO:0010829|negative regulation of glucose transport, ! BMP signaling pathway GO:0030509 64 32 3,000 3,187E-05 1,095E-03 ! DNA damage checkpoint GO:0000077 71 33 3,000 3,61E-05 1,223E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 3,811E-05 1,273E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 3,811E-05 1,256E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell growth GO:0030308 132 67 4,000 4,043E-05 1,315E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 4,043E-05 1,297E-03 ! negative regulation of secretion GO:0051048 63 35 3,000 4,579E-05 1,45E-03 ! neutral lipid metabolic process GO:0006638 50 35 3,000 4,579E-05 1,431E-03 GO:0006639|acylglycerol metabolic process, ! negative regulation of cell size GO:0045792 134 69 4,000 4,662E-05 1,438E-03 ! cell-cell junction assembly GO:0007043 27 13 2,000 4,933E-05 1,502E-03 ! cell junction organization GO:0034330 86 36 3,000 5,129E-05 1,542E-03 ! DNA integrity checkpoint GO:0031570 75 36 3,000 5,129E-05 1,523E-03 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 5,129E-05 1,505E-03 ! negative regulation of DNA binding GO:0043392 68 37 3,000 5,725E-05 1,659E-03 ! glycerol ether metabolic process GO:0006662 53 37 3,000 5,725E-05 1,64E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 5,725E-05 1,621E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 6,252E-05 1,749E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 6,252E-05 1,729E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 29 14 2,000 6,252E-05 1,709E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 6,37E-05 1,722E-03 GO:0042593|glucose homeostasis, ! organic ether metabolic process GO:0018904 55 39 3,000 7,067E-05 1,889E-03 ! heterophilic cell adhesion GO:0007157 39 15 2,000 7,783E-05 2,058E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7,783E-05 2,035E-03 ! positive regulation of biomineral formation GO:0070169 30 15 2,000 7,783E-05 2,013E-03 ! regulation of hormone secretion GO:0046883 62 40 3,000 7,817E-05 2,001E-03 ! negative regulation of binding GO:0051100 72 40 3,000 7,817E-05 1,98E-03 ! hormone-mediated signaling GO:0009755 74 41 3,000 8,624E-05 2,161E-03 ! polyol metabolic process GO:0019751 66 41 3,000 8,624E-05 2,139E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 8,932E-05 2,193E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 9,539E-05 2,318E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,006E-04 2,421E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,067E-04 2,541E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,153E-04 2,721E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,153E-04 2,694E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,196E-04 2,767E-03 ! cell growth GO:0016049 84 45 3,000 1,247E-04 2,857E-03 ! response to unfolded protein GO:0006986 131 85 4,000 1,265E-04 2,871E-03 ! regulation of protein transport GO:0051223 154 87 4,000 1,412E-04 3,175E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of cell adhesion GO:0030155 212 89 4,000 1,572E-04 3,501E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,607E-04 3,546E-03 ! cellular component disassembly GO:0022411 86 48 3,000 1,607E-04 3,514E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,607E-04 3,482E-03 ! G1 phase GO:0051318 40 19 2,000 1,63E-04 3,502E-03 ! cell-cell junction organization GO:0045216 35 19 2,000 1,63E-04 3,471E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 1,742E-04 3,676E-03 ! response to protein stimulus GO:0051789 149 91 4,000 1,745E-04 3,65E-03 ! positive regulation of ossification GO:0045778 47 20 2,000 1,91E-04 3,961E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,91E-04 3,927E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,91E-04 3,894E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,91E-04 3,861E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,036E-04 4,083E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 90 52 3,000 2,196E-04 4,367E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,219E-04 4,375E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,219E-04 4,34E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,219E-04 4,305E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,219E-04 4,27E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 2,219E-04 4,237E-03 ! regulation of protein localization GO:0032880 176 97 4,000 2,353E-04 4,457E-03 ! positive regulation of bone remodeling GO:0046852 51 22 2,000 2,558E-04 4,809E-03 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 2,000 2,558E-04 4,771E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,558E-04 4,735E-03 ! ureteric bud development GO:0001657 43 22 2,000 2,558E-04 4,699E-03 ! cell cycle arrest GO:0007050 213 100 4,000 2,711E-04 4,942E-03 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 2,73E-04 4,939E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 2,927E-04 5,256E-03 ! regulation of bone mineralization GO:0030500 49 23 2,000 2,93E-04 5,221E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,169E-04 5,607E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 3,169E-04 5,566E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 3,169E-04 5,525E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,169E-04 5,486E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,169E-04 5,447E-03 ! sister chromatid cohesion GO:0007062 12 5 1,000 3,169E-04 5,408E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,169E-04 5,37E-03 ! lipoprotein catabolic process GO:0042159 11 5 1,000 3,169E-04 5,332E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,169E-04 5,295E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,169E-04 5,259E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,169E-04 5,223E-03 ! stem cell division GO:0017145 11 5 1,000 3,169E-04 5,187E-03 GO:0048103|somatic stem cell division, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,334E-04 5,421E-03 ! regulation of behavior GO:0050795 43 24 2,000 3,334E-04 5,384E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 3,58E-04 5,742E-03 ! regulation of biomineral formation GO:0070167 51 25 2,000 3,773E-04 6,012E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,773E-04 5,973E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,819E-04 6,005E-03 ! regulation of heart contraction GO:0008016 110 60 3,000 3,819E-04 5,966E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,819E-04 5,928E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 4,248E-04 6,551E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 4,603E-04 7,055E-03 ! neuron apoptosis GO:0051402 9 6 1,000 4,736E-04 7,212E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,736E-04 7,167E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,736E-04 7,122E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 4,759E-04 7,112E-03 ! autophagy GO:0006914 41 27 2,000 4,759E-04 7,068E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,759E-04 7,024E-03 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 4,889E-04 7,172E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 4,889E-04 7,129E-03 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of protein modification process GO:0031400 60 28 2,000 5,308E-04 7,693E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 5,82E-04 8,385E-03 ! chromosome segregation GO:0007059 113 67 3,000 5,82E-04 8,335E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 6,157E-04 8,765E-03 ! urogenital system development GO:0001655 137 69 3,000 6,507E-04 9,209E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 6,523E-04 9,178E-03 ! prostate gland development GO:0030850 13 7 1,000 6,606E-04 9,24E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 6,606E-04 9,187E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 6,606E-04 9,134E-03 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 6,606E-04 9,082E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 6,606E-04 9,03E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 6,606E-04 8,979E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 6,606E-04 8,929E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 7,642E-04 0,01027194 ! metanephros development GO:0001656 74 32 2,000 7,903E-04 0,01056397 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 7,903E-04 0,01050561 ! regulation of transcription factor activity GO:0051090 126 74 3,000 8,472E-04 0,01120014 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 3,000 8,472E-04 0,01113893 ! leukocyte chemotaxis GO:0030595 50 33 2,000 8,657E-04 0,01132054 GO:0060326|cell chemotaxis, ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 1,000 8,775E-04 0,011412 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 8,775E-04 0,01135065 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 8,775E-04 0,01128995 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,775E-04 0,0112299 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 8,775E-04 0,01117048 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 8,775E-04 0,01111169 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 1,082E-03 0,01363332 ! maintenance of protein location in cell GO:0032507 86 36 2,000 1,119E-03 0,01402131 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,119E-03 0,01394866 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,124E-03 0,01393968 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,124E-03 0,0138682 ! receptor clustering GO:0043113 18 9 1,000 1,124E-03 0,01379744 ! intestinal cholesterol absorption GO:0030299 16 9 1,000 1,124E-03 0,0137274 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,124E-03 0,01365807 ! cholesterol metabolic process GO:0008203 136 82 3,000 1,243E-03 0,01503321 ! nucleus organization GO:0006997 67 38 2,000 1,311E-03 0,01577204 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,4E-03 0,01675505 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,4E-03 0,01667211 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,4E-03 0,01658998 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,4E-03 0,01650865 ! lung alveolus development GO:0048286 26 10 1,000 1,4E-03 0,01642812 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,4E-03 0,01634838 GO:0045685|regulation of glial cell differentiation, ! midbrain development GO:0030901 13 10 1,000 1,4E-03 0,0162694 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,4E-03 0,01619118 ! localization within membrane GO:0051668 20 10 1,000 1,4E-03 0,01611371 ! maintenance of protein location GO:0045185 91 40 2,000 1,523E-03 0,01744659 ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,615E-03 0,01841173 ! regulation of DNA binding GO:0051101 155 88 3,000 1,615E-03 0,01832488 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 2,000 1,636E-03 0,01848192 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,636E-03 0,01839556 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,704E-03 0,01907355 ! lipid digestion GO:0044241 18 11 1,000 1,704E-03 0,01898525 ! cardiac cell differentiation GO:0035051 31 11 1,000 1,704E-03 0,01889776 ! sterol metabolic process GO:0016125 152 91 3,000 1,826E-03 0,02015797 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,879E-03 0,02063813 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,879E-03 0,02054432 ! maintenance of location in cell GO:0051651 97 44 2,000 2,008E-03 0,02185692 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,038E-03 0,02208396 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,038E-03 0,02198493 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 2,038E-03 0,02188678 ! mitotic spindle organization GO:0007052 21 12 1,000 2,038E-03 0,02178951 ! T cell homeostasis GO:0043029 25 12 1,000 2,038E-03 0,02169309 ! leukocyte migration GO:0050900 68 45 2,000 2,142E-03 0,02270477 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,142E-03 0,02260518 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,306E-03 0,0242322 ! hormone metabolic process GO:0042445 157 97 3,000 2,306E-03 0,02412685 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,399E-03 0,02498895 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,399E-03 0,02488124 ! positive regulation of defense response GO:0031349 76 47 2,000 2,428E-03 0,02506801 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,579E-03 0,02651482 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,789E-03 0,02855086 ! intestinal absorption GO:0050892 25 14 1,000 2,789E-03 0,02842988 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,789E-03 0,02830992 ! regulation of ossification GO:0030278 117 50 2,000 2,898E-03 0,02929809 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,898E-03 0,0291755 ! vesicle organization GO:0016050 107 51 2,000 3,067E-03 0,03074223 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 3,067E-03 0,03061466 ! isoprenoid biosynthetic process GO:0008299 32 15 1,000 3,206E-03 0,03187135 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,206E-03 0,03174019 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 3,206E-03 0,03161011 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,241E-03 0,03182655 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 3,241E-03 0,03169718 ! synapse organization GO:0050808 85 52 2,000 3,241E-03 0,03156885 ! activation of phospholipase C activity GO:0007202 103 54 2,000 3,607E-03 0,03499763 GO:0010863|positive regulation of phospholipase C activity, ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,65E-03 0,03526875 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 3,65E-03 0,03512768 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 3,65E-03 0,03498772 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,65E-03 0,03484888 ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 3,8E-03 0,03613537 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,121E-03 0,03903874 ! signal complex assembly GO:0007172 41 17 1,000 4,121E-03 0,03888564 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,121E-03 0,03873375 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,121E-03 0,03858303 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,203E-03 0,03919537 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,203E-03 0,03904404 ! regulation of phospholipase activity GO:0010517 106 57 2,000 4,203E-03 0,03889387 ! maintenance of location GO:0051235 118 57 2,000 4,203E-03 0,03874485 ! regulation of tissue remodeling GO:0034103 140 58 2,000 4,414E-03 0,04053436 ! positive regulation of lipase activity GO:0060193 108 58 2,000 4,414E-03 0,04038024 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,619E-03 0,04209797 ! memory GO:0007613 31 18 1,000 4,619E-03 0,04193911 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,619E-03 0,04178144 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 4,619E-03 0,04162496 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 4,619E-03 0,04146964 ! DNA catabolic process GO:0006308 86 59 2,000 4,631E-03 0,04142301 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 4,631E-03 0,04126959 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,855E-03 0,04310293 ! kidney development GO:0001822 122 60 2,000 4,855E-03 0,04294446 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,085E-03 0,04481481 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 5,143E-03 0,04516511 ! lipid phosphorylation GO:0046834 35 19 1,000 5,143E-03 0,04500087 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,143E-03 0,04483782 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,143E-03 0,04467595 ! pigmentation during development GO:0048066 41 19 1,000 5,143E-03 0,04451525 ! cellular response to unfolded protein GO:0034620 33 19 1,000 5,143E-03 0,0443557 GO:0030968|endoplasmic reticulum unfolded protein response, ! plasma membrane fusion GO:0045026 28 19 1,000 5,143E-03 0,04419728 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,143E-03 0,04404 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,143E-03 0,04388383 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 5,694E-03 0,04840712 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,694E-03 0,04823667 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 5,694E-03 0,04806742 ! negative regulation of translation GO:0017148 29 20 1,000 5,694E-03 0,04789935 ! positive regulation of cell motion GO:0051272 146 64 2,000 5,814E-03 0,048742 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 6,27E-03 0,05237864 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 6,27E-03 0,0521974 ! regulation of vasoconstriction GO:0019229 39 21 1,000 6,27E-03 0,05201741 ! homeostasis of number of cells GO:0048872 114 67 2,000 6,603E-03 0,05459318 ! glutamate signaling pathway GO:0007215 41 22 1,000 6,871E-03 0,05661644 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 6,871E-03 0,05642321 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,871E-03 0,0562313 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,871E-03 0,05604068 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,871E-03 0,05585136 ! protein stabilization GO:0050821 39 22 1,000 6,871E-03 0,0556633 ! regulation of lipase activity GO:0060191 130 68 2,000 6,879E-03 0,05554187 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 7,498E-03 0,06033226 ! leukocyte adhesion GO:0007159 50 23 1,000 7,498E-03 0,06013115 ! platelet activation GO:0030168 37 23 1,000 7,498E-03 0,05993138 ! negative regulation of catabolic process GO:0009895 50 23 1,000 7,498E-03 0,05973293 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,149E-03 0,06470744 ! digestive system process GO:0022600 39 24 1,000 8,149E-03 0,06449459 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,149E-03 0,06428313 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,149E-03 0,06407305 ! learning or memory GO:0007611 147 73 2,000 8,363E-03 0,06554517 ! meiosis GO:0007126 121 74 2,000 8,681E-03 0,06781324 GO:0051327|M phase of meiotic cell cycle, ! myelination GO:0042552 45 25 1,000 8,825E-03 0,06871298 ! phototransduction GO:0007602 33 25 1,000 8,825E-03 0,06849133 ! receptor metabolic process GO:0043112 46 25 1,000 8,825E-03 0,0682711 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 8,825E-03 0,06805228 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 8,825E-03 0,06783486 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 9,006E-03 0,06900453 ! meiotic cell cycle GO:0051321 122 75 2,000 9,006E-03 0,06878547 ! steroid biosynthetic process GO:0006694 131 76 2,000 9,337E-03 0,07109264 ! macromolecular complex disassembly GO:0032984 53 26 1,000 9,525E-03 0,07229182 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 9,525E-03 0,07206448 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 9,525E-03 0,07183858 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 9,525E-03 0,07161408 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 9,525E-03 0,07139098 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,525E-03 0,07116927 GO:0045840|positive regulation of mitosis, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01002161 0,07465014 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01024864 0,07610565 ! fat cell differentiation GO:0045444 50 27 1,000 0,01024864 0,07587148 ! base-excision repair GO:0006284 41 27 1,000 0,01024864 0,07563874 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01024864 0,07540743 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 0,01099617 0,08066093 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01099617 0,08041576 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01099617 0,08017208 ! synaptogenesis GO:0007416 42 28 1,000 0,01099617 0,07992986 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01099617 0,07968911 ! sterol biosynthetic process GO:0016126 52 29 1,000 0,01176703 0,08501945 ! detection of light stimulus GO:0009583 38 29 1,000 0,01176703 0,0847649 ! zinc ion transport GO:0006829 45 30 1,000 0,01256094 0,09021379 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01256094 0,08994529 GO:0008366|axon ensheathment, ! tube morphogenesis GO:0035239 176 86 2,000 0,01304582 0,09314022 ! mitochondrion organization GO:0007005 148 86 2,000 0,01304582 0,09286466 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01337761 0,09494551 GO:0055092|sterol homeostasis, ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01337761 0,09466626 ! mesoderm formation GO:0001707 69 31 1,000 0,01337761 0,09438864 ! cholesterol transport GO:0030301 56 32 1,000 0,01421676 0,10001617 ! spliceosome assembly GO:0000245 67 32 1,000 0,01421676 0,09972457 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01421676 0,09943468 ! hindbrain development GO:0030902 61 32 1,000 0,01421676 0,09914646 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01473229 0,1024448 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01507812 0,10454741 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01507812 0,10424699 ! sterol transport GO:0015918 57 33 1,000 0,01507812 0,10394828 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01507812 0,10365129 ! regulation of defense response GO:0031347 149 92 2,000 0,01561961 0,10706774 ! glial cell differentiation GO:0010001 63 34 1,000 0,0159614 0,1090998 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,0159614 0,10879074 ! transcription initiation GO:0006352 153 94 2,000 0,01653645 0,1123918 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01653645 0,11207521 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01686634 0,11398991 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01686634 0,11367061 ! odontogenesis GO:0042476 66 35 1,000 0,01686634 0,1133531 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01686634 0,11303735 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,01700597 0,11365658 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01779266 0,11858486 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01779266 0,11825728 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of cell development GO:0010720 80 36 1,000 0,01779266 0,1179315 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01874009 0,12386994 ! meiosis I GO:0007127 65 37 1,000 0,01874009 0,12353057 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01874009 0,12319305 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01874009 0,12285738 ! lipid homeostasis GO:0055088 67 38 1,000 0,01970837 0,12885418 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01970837 0,12850498 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,01970837 0,12815767 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01970837 0,12781223 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 77 39 1,000 0,02069723 0,13386435 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02069723 0,13350547 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02170641 0,13964073 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,02170641 0,13926835 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02273566 0,14548402 ! gliogenesis GO:0042063 88 41 1,000 0,02273566 0,14509812 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02273566 0,14471426 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02273566 0,14433243 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,0237847 0,15059472 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,0248533 0,15694759 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,0248533 0,15653673 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,0248533 0,15612802 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02594118 0,16253774 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02704812 0,16903317 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02807057 0,17496837 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02807057 0,17451625 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02807057 0,17406647 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02807057 0,173619 ! neuron fate determination GO:0048664 7 5 0,000 0,02807057 0,17317382 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02807057 0,17273092 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02807057 0,17229028 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02807057 0,17185188 ! polyol transport GO:0015791 12 5 0,000 0,02807057 0,17141571 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02807057 0,17098175 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02807057 0,17054998 ! response to superoxide GO:0000303 10 5 0,000 0,02807057 0,17012038 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02807057 0,16969294 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02807057 0,16926764 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02807057 0,16884448 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02807057 0,16842342 ! female meiosis GO:0007143 7 5 0,000 0,02807057 0,16800445 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02807057 0,16758757 ! cobalt ion transport GO:0006824 11 5 0,000 0,02807057 0,16717275 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02807057 0,16675998 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02807057 0,16634924 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02807057 0,16594052 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02807057 0,1655338 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02807057 0,16512907 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02807057 0,16472632 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02807057 0,16432552 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02807057 0,16392668 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02807057 0,16352976 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02807057 0,16313476 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02807057 0,16274166 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02807057 0,16235046 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02807057 0,16196113 ! negative chemotaxis GO:0050919 14 5 0,000 0,02807057 0,16157366 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02807057 0,16118804 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02807057 0,16080426 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02807057 0,1604223 ! behavioral response to pain GO:0048266 9 5 0,000 0,02807057 0,16004216 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02807057 0,15966381 ! Notch receptor processing GO:0007220 8 5 0,000 0,02807057 0,15928724 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02807057 0,15891245 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02807057 0,15853941 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02807057 0,15816813 ! copulation GO:0007620 9 5 0,000 0,02807057 0,15779858 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02807057 0,15743075 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02807057 0,15706463 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02807057 0,15670021 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02807057 0,15633748 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02807057 0,15597642 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02807057 0,15561703 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02807057 0,15525929 ! grooming behavior GO:0007625 6 5 0,000 0,02807057 0,15490319 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02807057 0,15454872 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02807057 0,15419587 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02807057 0,15384462 ! response to protozoan GO:0001562 10 5 0,000 0,02807057 0,15349498 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02807057 0,15314692 ! lymph vessel development GO:0001945 10 5 0,000 0,02807057 0,15280043 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02807057 0,15245551 ! endochondral ossification GO:0001958 16 5 0,000 0,02807057 0,15211214 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02807057 0,15177032 ! parathyroid gland development GO:0060017 13 5 0,000 0,02807057 0,15143002 ! anagen GO:0042640 6 5 0,000 0,02807057 0,15109125 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02807057 0,150754 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02807057 0,15041824 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02807057 0,15008398 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02807057 0,1497512 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02807057 0,14941989 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02807057 0,14909004 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02807057 0,14876165 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02807057 0,1484347 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02807057 0,14810919 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02807057 0,1477851 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02807057 0,14746242 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02807057 0,14714116 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02807057 0,14682128 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02807057 0,1465028 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02807057 0,14618569 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02807057 0,14586996 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02807057 0,14555558 ! histidine catabolic process GO:0006548 6 5 0,000 0,02807057 0,14524256 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02807057 0,14493088 ! microvillus organization GO:0032528 7 5 0,000 0,02807057 0,14462054 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02807057 0,14431152 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02807057 0,14400382 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02807057 0,14369743 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02807057 0,14339234 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02807057 0,14308854 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02807057 0,14278603 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02807057 0,14248479 ! polyol catabolic process GO:0046174 7 5 0,000 0,02807057 0,14218482 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02807057 0,14188611 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02807057 0,14158866 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02807057 0,14129245 ! muscle cell migration GO:0014812 8 5 0,000 0,02807057 0,14099747 ! mitochondrial fission GO:0000266 8 5 0,000 0,02807057 0,14070373 ! mRNA transcription GO:0009299 9 5 0,000 0,02807057 0,14041121 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02807057 0,1401199 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02807057 0,13982979 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02807057 0,13954089 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02807057 0,13925318 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02807057 0,13896665 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02807057 0,13868129 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02807057 0,13839711 ! response to food GO:0032094 6 5 0,000 0,02807057 0,13811409 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02807057 0,13783222 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02807057 0,13755151 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02807057 0,13727193 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02807057 0,13699349 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02807057 0,13671617 ! forebrain neuron development GO:0021884 13 5 0,000 0,02807057 0,13643998 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02807057 0,1361649 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02807057 0,13589093 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02807057 0,13561805 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02807057 0,13534627 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02807057 0,13507558 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02807057 0,13480597 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02807057 0,13453743 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02807057 0,13426996 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02807057 0,13400355 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02807057 0,1337382 ! basic amino acid transport GO:0015802 11 5 0,000 0,02807057 0,13347389 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02807057 0,13321063 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02807057 0,13294841 ! depyrimidination GO:0045008 10 5 0,000 0,02807057 0,13268721 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02807057 0,13242704 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02807057 0,13216789 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02807057 0,13190975 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02807057 0,13165261 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02807057 0,13139648 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02807057 0,13114134 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02807057 0,13088719 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02807057 0,13063402 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02807057 0,13038183 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02807057 0,13013062 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02807057 0,12988037 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02807057 0,12963108 ! response to arsenic GO:0046685 10 5 0,000 0,02807057 0,12938274 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02807057 0,12913535 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02807057 0,12888891 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02807057 0,12864341 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02807057 0,12839884 ! response to cadmium ion GO:0046686 7 5 0,000 0,02807057 0,1281552 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02807057 0,12791248 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02807057 0,12767068 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02807057 0,12742979 ! decidualization GO:0046697 11 5 0,000 0,02807057 0,12718981 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02807057 0,12695073 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02807057 0,12671255 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02807057 0,12647526 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02807057 0,12623886 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02807057 0,12600334 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02807057 0,1257687 ! neural tube patterning GO:0021532 7 5 0,000 0,02807057 0,12553493 ! embryonic cleavage GO:0040016 6 5 0,000 0,02807057 0,12530202 ! peroxisome fission GO:0016559 5 5 0,000 0,02807057 0,12506998 ! histone demethylation GO:0016577 10 5 0,000 0,02807057 0,1248388 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02807057 0,12460847 ! mitotic recombination GO:0006312 9 5 0,000 0,02807057 0,12437899 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02807057 0,12415035 ! metaphase plate congression GO:0051310 7 5 0,000 0,02807057 0,12392255 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02807057 0,12369559 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02807057 0,12346945 ! enteric nervous system development GO:0048484 8 5 0,000 0,02807057 0,12324414 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02807057 0,12301965 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02807057 0,12279598 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02807057 0,12257312 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02807057 0,12235107 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02807057 0,12212982 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02807057 0,12190937 ! plasminogen activation GO:0031639 5 5 0,000 0,02807057 0,12168971 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02807057 0,12147085 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02807057 0,12125277 ! metaphase GO:0051323 8 5 0,000 0,02807057 0,12103547 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02807057 0,12081894 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02807057 0,1206032 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02807057 0,12038822 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02807057 0,120174 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02807057 0,11996055 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02807057 0,11974786 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02807057 0,11953591 ! response to redox state GO:0051775 5 5 0,000 0,02807057 0,11932472 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02807057 0,11911427 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02807057 0,11890456 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02807057 0,11869559 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02807057 0,11848735 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02807057 0,11827984 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02807057 0,11807306 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02807057 0,117867 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02807057 0,11766166 ! striatum development GO:0021756 9 5 0,000 0,02807057 0,11745703 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02807057 0,11725311 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02807057 0,1170499 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02807057 0,11684739 ! glial cell migration GO:0008347 11 5 0,000 0,02807057 0,11664558 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02807057 0,11644447 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02807057 0,11624405 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02807057 0,11604431 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02807057 0,11584527 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02807057 0,1156469 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02807057 0,11544921 ! neuroprotection GO:0043526 6 5 0,000 0,02807057 0,1152522 ! neural plate development GO:0001840 8 5 0,000 0,02807057 0,11505586 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02807057 0,11486019 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02807057 0,11466518 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02807057 0,11447083 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02807057 0,11427714 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02807057 0,11408411 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02807057 0,11389172 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02807057 0,11369998 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02807057 0,11350889 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02807057 0,11331844 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02807057 0,11312863 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02807057 0,11293945 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02807057 0,1127509 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02807057 0,11256298 ! drug metabolic process GO:0017144 6 5 0,000 0,02807057 0,11237569 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02807057 0,11218902 ! organ regeneration GO:0031100 7 5 0,000 0,02807057 0,11200297 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02807057 0,11181753 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02807057 0,11163271 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02807057 0,1114485 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02817384 0,11167425 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02817384 0,11149058 ! pigmentation GO:0043473 100 46 1,000 0,02817384 0,11130751 ! response to insulin stimulus GO:0032868 95 46 1,000 0,02817384 0,11112503 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02817384 0,11094316 ! response to calcium ion GO:0051592 81 47 1,000 0,02931812 0,11526046 ! endosome transport GO:0016197 108 47 1,000 0,02931812 0,11507243 ! activation of caspase activity GO:0006919 84 48 1,000 0,0304807 0,11944067 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0304807 0,11924646 ! regulation of action potential GO:0001508 95 49 1,000 0,03166135 0,12366429 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,03166135 0,12346386 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03166135 0,12326408 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03358996 0,1305613 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03358996 0,13035072 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03358996 0,13014082 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03358996 0,12993159 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03358996 0,12972303 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03358996 0,12951514 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03358996 0,12930792 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03358996 0,12910135 ! sleep GO:0030431 13 6 0,000 0,03358996 0,12889545 ! response to oxygen radical GO:0000305 11 6 0,000 0,03358996 0,1286902 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03358996 0,12848561 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03358996 0,12828166 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03358996 0,12807836 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03358996 0,12787571 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03358996 0,12767369 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03358996 0,12747231 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03358996 0,12727157 ! forebrain regionalization GO:0021871 8 6 0,000 0,03358996 0,12707146 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03358996 0,12687197 ! male meiosis GO:0007140 7 6 0,000 0,03358996 0,12667312 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03358996 0,12647488 ! response to zinc ion GO:0010043 9 6 0,000 0,03358996 0,12627726 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03358996 0,12608026 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03358996 0,12588387 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03358996 0,1256881 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03358996 0,12549293 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03358996 0,12529837 ! malate metabolic process GO:0006108 11 6 0,000 0,03358996 0,12510441 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03358996 0,12491105 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03358996 0,12471828 ! protein refolding GO:0042026 15 6 0,000 0,03358996 0,12452611 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03358996 0,12433453 ! opsonization GO:0008228 8 6 0,000 0,03358996 0,12414354 ! mating behavior GO:0007617 7 6 0,000 0,03358996 0,12395314 ! neuron remodeling GO:0016322 15 6 0,000 0,03358996 0,12376332 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03358996 0,12357408 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03358996 0,12338542 ! equilibrioception GO:0050957 14 6 0,000 0,03358996 0,12319733 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03358996 0,12300981 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03358996 0,12282287 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03358996 0,12263649 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03358996 0,12245068 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03358996 0,12226543 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03358996 0,12208074 ! toxin metabolic process GO:0009404 11 6 0,000 0,03358996 0,1218966 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03358996 0,12171302 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03358996 0,12153 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03358996 0,12134752 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03358996 0,12116559 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03358996 0,1209842 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03358996 0,12080336 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03358996 0,12062306 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03358996 0,12044329 ! thymic T cell selection GO:0045061 12 6 0,000 0,03358996 0,12026406 ! protein lipoylation GO:0009249 10 6 0,000 0,03358996 0,12008536 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03358996 0,11990719 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03358996 0,11972955 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03358996 0,11955244 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03358996 0,11937585 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03358996 0,11919977 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03358996 0,11902422 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03358996 0,11884919 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03358996 0,11867467 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03358996 0,11850066 ! hyperosmotic response GO:0006972 9 6 0,000 0,03358996 0,11832716 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03358996 0,11815416 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03358996 0,11798168 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03358996 0,11780969 ! urea metabolic process GO:0019627 7 6 0,000 0,03358996 0,11763821 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03358996 0,11746722 ! neutrophil activation GO:0042119 8 6 0,000 0,03358996 0,11729673 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03358996 0,11712674 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03358996 0,11695723 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03358996 0,11678822 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03358996 0,11661969 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03358996 0,11645165 ! nucleoside salvage GO:0043174 9 6 0,000 0,03358996 0,1162841 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03358996 0,11611702 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03358996 0,11595043 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03358996 0,11578431 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03358996 0,11561867 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03358996 0,1154535 ! carnitine transport GO:0015879 10 6 0,000 0,03358996 0,1152888 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03358996 0,11512457 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03358996 0,11496081 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03358996 0,11479751 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03358996 0,11463468 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03358996 0,11447231 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03358996 0,11431039 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03358996 0,11414894 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03358996 0,11398794 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03358996 0,11382739 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03358996 0,1136673 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03358996 0,11350765 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03358996 0,11334845 ! neural nucleus development GO:0048857 14 6 0,000 0,03358996 0,1131897 ! response to UV-C GO:0010225 11 6 0,000 0,03358996 0,1130314 ! astrocyte development GO:0014002 15 6 0,000 0,03358996 0,11287353 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03358996 0,11271611 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03358996 0,11255912 ! interaction with symbiont GO:0051702 13 6 0,000 0,03358996 0,11240257 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03358996 0,11224645 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03358996 0,11209077 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03358996 0,11193552 ! response to copper ion GO:0046688 10 6 0,000 0,03358996 0,1117807 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03358996 0,11162631 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03358996 0,11147234 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03358996 0,1113188 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03358996 0,11116568 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03358996 0,11101298 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03358996 0,1108607 ! hair follicle maturation GO:0048820 7 6 0,000 0,03358996 0,11070883 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03358996 0,11055738 ! Schwann cell development GO:0014044 15 6 0,000 0,03358996 0,11040635 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03358996 0,11025573 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03358996 0,11010551 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03358996 0,10995571 ! subpallium development GO:0021544 10 6 0,000 0,03358996 0,10980631 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03358996 0,10965732 ! histone ubiquitination GO:0016574 8 6 0,000 0,03358996 0,10950874 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03358996 0,10936055 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03358996 0,10921277 ! G2 phase GO:0051319 16 6 0,000 0,03358996 0,10906538 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03358996 0,10891839 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03358996 0,1087718 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03358996 0,1086256 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03358996 0,1084798 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03358996 0,10833438 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03358996 0,10818935 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03358996 0,10804472 ! receptor internalization GO:0031623 10 6 0,000 0,03358996 0,10790046 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03358996 0,1077566 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03358996 0,10761311 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03358996 0,10747001 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03358996 0,10732729 ! protein deubiquitination GO:0016579 14 6 0,000 0,03358996 0,10718494 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03358996 0,10704298 ! protein destabilization GO:0031648 9 6 0,000 0,03358996 0,10690139 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03358996 0,10676017 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03358996 0,10661932 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03358996 0,10647885 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03358996 0,10633875 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03358996 0,10619901 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03358996 0,10605964 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03358996 0,10592064 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03358996 0,105782 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03358996 0,10564372 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03358996 0,10550581 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03358996 0,10536825 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03358996 0,10523105 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03358996 0,10509421 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03358996 0,10495772 ! catecholamine transport GO:0051937 9 6 0,000 0,03358996 0,10482159 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03358996 0,10468581 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03358996 0,10455038 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03358996 0,10441531 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03358996 0,10428058 ! maternal placenta development GO:0001893 12 6 0,000 0,03358996 0,1041462 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03358996 0,10401216 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03358996 0,10387847 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03358996 0,10374512 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03358996 0,10361211 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03358996 0,10347945 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03358996 0,10334712 ! membrane fusion GO:0006944 110 52 1,000 0,03530927 0,1084982 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03655978 0,11219749 ! tRNA transcription GO:0009304 14 7 0,000 0,03907819 0,11977341 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03907819 0,11962103 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03907819 0,11946904 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03907819 0,11931742 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03907819 0,1191662 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03907819 0,11901536 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03907819 0,11886489 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03907819 0,11871481 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03907819 0,11856511 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03907819 0,11841578 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03907819 0,11826683 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03907819 0,11811825 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03907819 0,11797005 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03907819 0,11782222 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03907819 0,11767476 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03907819 0,11752766 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03907819 0,11738094 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03907819 0,11723458 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03907819 0,11708858 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03907819 0,11694295 ! glycolipid transport GO:0046836 10 7 0,000 0,03907819 0,11679768 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03907819 0,11665277 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03907819 0,11650822 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03907819 0,11636402 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03907819 0,11622019 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03907819 0,1160767 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03907819 0,11593358 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03907819 0,1157908 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03907819 0,11564838 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03907819 0,1155063 ! mRNA stabilization GO:0048255 18 7 0,000 0,03907819 0,11536458 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03907819 0,1152232 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03907819 0,11508217 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03907819 0,11494148 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03907819 0,11480114 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03907819 0,11466113 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03907819 0,11452147 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03907819 0,11438215 ! lipoprotein transport GO:0042953 14 7 0,000 0,03907819 0,11424317 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03907819 0,11410453 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03907819 0,11396622 ! rhythmic behavior GO:0007622 15 7 0,000 0,03907819 0,11382825 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03907819 0,11369061 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03907819 0,1135533 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03907819 0,11341632 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03907819 0,11327968 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03907819 0,11314336 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03907819 0,11300737 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03907819 0,11287171 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03907819 0,11273637 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03907819 0,11260135 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03907819 0,11246666 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03907819 0,11233229 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03907819 0,11219825 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03907819 0,11206452 ! spinal cord patterning GO:0021511 13 7 0,000 0,03907819 0,11193111 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03907819 0,11179802 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03907819 0,11166524 ! adrenal gland development GO:0030325 17 7 0,000 0,03907819 0,11153278 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03907819 0,11140063 ! ovulation GO:0030728 9 7 0,000 0,03907819 0,11126879 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03907819 0,11113727 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03907819 0,11100606 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03907819 0,11087515 ! microtubule nucleation GO:0007020 20 7 0,000 0,03907819 0,11074456 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03907819 0,11061427 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03907819 0,11048429 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03907819 0,11035461 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03907819 0,11022524 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03907819 0,11009617 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03907819 0,1099674 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03907819 0,10983894 ! galactose metabolic process GO:0006012 13 7 0,000 0,03907819 0,10971077 ! vesicle fusion GO:0006906 17 7 0,000 0,03907819 0,1095829 ! response to dietary excess GO:0002021 8 7 0,000 0,03907819 0,10945533 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03907819 0,10932806 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03907819 0,10920108 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03907819 0,1090744 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03907819 0,10894801 ! purine salvage GO:0043101 10 7 0,000 0,03907819 0,10882191 ! nucleoside transport GO:0015858 8 7 0,000 0,03907819 0,1086961 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03907819 0,10857059 ! parturition GO:0007567 14 7 0,000 0,03907819 0,10844536 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03907819 0,10832043 ! rRNA modification GO:0000154 14 7 0,000 0,03907819 0,10819578 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03907819 0,10807141 ! spindle checkpoint GO:0031577 15 7 0,000 0,03907819 0,10794734 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03907819 0,10782354 ! macrophage differentiation GO:0030225 11 7 0,000 0,03907819 0,10770004 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03907819 0,10757681 ! centrosome duplication GO:0051298 13 7 0,000 0,03907819 0,10745386 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03907819 0,1073312 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03907819 0,10720881 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03907819 0,10708671 ! fibrinolysis GO:0042730 10 7 0,000 0,03907819 0,10696488 ! eating behavior GO:0042755 7 7 0,000 0,03907819 0,10684333 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03907819 0,10672206 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03907819 0,10660106 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03907819 0,10648033 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03907819 0,10635988 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03907819 0,1062397 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03907819 0,10611979 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03907819 0,10600015 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03907819 0,10588078 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03907819 0,10576168 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03907819 0,10564284 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03907819 0,10552428 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03907819 0,10540598 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03907819 0,10528794 ! regulation of meiosis GO:0040020 12 7 0,000 0,03907819 0,10517017 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03907819 0,10505266 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03907819 0,10493541 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03907819 0,10481843 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03907819 0,1047017 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03907819 0,10458524 ! transcription termination GO:0006353 13 7 0,000 0,03907819 0,10446903 ! response to tumor cell GO:0002347 13 7 0,000 0,03907819 0,10435309 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03907819 0,1042374 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03907819 0,10412196 ! anaphase GO:0051322 17 7 0,000 0,03907819 0,10400678 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03907819 0,10389186 ! axonal fasciculation GO:0007413 18 7 0,000 0,03907819 0,10377719 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03907819 0,10366277 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03907819 0,1035486 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03907819 0,10343469 ! diuresis GO:0030146 12 7 0,000 0,03907819 0,10332102 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03907819 0,10320761 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03907819 0,10309444 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03907819 0,10298152 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03907819 0,10286885 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03907819 0,10275643 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03907819 0,10264425 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03907819 0,10253231 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03907819 0,10242062 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03907819 0,10230917 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03907819 0,10219797 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03907819 0,102087 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03907819 0,10197628 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03907819 0,1018658 ! lymph node development GO:0048535 10 7 0,000 0,03907819 0,10175555 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03907819 0,10164555 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03907819 0,10153578 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03907819 0,10142625 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03907819 0,10131695 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03907819 0,10120789 ! adult feeding behavior GO:0008343 9 7 0,000 0,03907819 0,10109907 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03907819 0,10099047 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03907819 0,10088211 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03907819 0,10077399 ! muscle adaptation GO:0043500 14 7 0,000 0,03907819 0,10066609 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03907819 0,10055843 ! retina homeostasis GO:0001895 12 7 0,000 0,03907819 0,10045099 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03907819 0,10034379 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03907819 0,10023681 ! protein prenylation GO:0018342 18 7 0,000 0,03907819 0,10013006 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03907819 0,10002354 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03907819 0,09991725 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03907819 0,09981118 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03911123 0,09978964 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03911123 0,09968393 ! aging GO:0007568 103 55 1,000 0,03911123 0,09957844 ! gastrulation GO:0007369 112 55 1,000 0,03911123 0,09947318 ! heart morphogenesis GO:0003007 97 55 1,000 0,03911123 0,09936814 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04041171 0,1025639 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04041171 0,10245583 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04440947 0,11247282 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04440947 0,11235455 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04453544 0,1125549 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04453544 0,11243679 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04453544 0,11231893 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04453544 0,11220132 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04453544 0,11208395 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04453544 0,11196683 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04453544 0,11184996 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04453544 0,11173333 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04453544 0,11161694 ! meiotic prophase I GO:0007128 13 8 0,000 0,04453544 0,11150079 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04453544 0,11138489 ! oligopeptide transport GO:0006857 15 8 0,000 0,04453544 0,11126922 ! UTP metabolic process GO:0046051 8 8 0,000 0,04453544 0,1111538 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04453544 0,11103861 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04453544 0,11092367 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04453544 0,11080896 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04453544 0,11069448 ! succinate metabolic process GO:0006105 14 8 0,000 0,04453544 0,11058025 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04453544 0,11046625 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04453544 0,11035248 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04453544 0,11023895 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04453544 0,11012565 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04453544 0,11001259 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04453544 0,10989975 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04453544 0,10978715 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04453544 0,10967478 ! reflex GO:0060004 16 8 0,000 0,04453544 0,10956264 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04453544 0,10945073 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04453544 0,10933904 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04453544 0,10922758 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04453544 0,10911636 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04453544 0,10900535 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04453544 0,10889457 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04453544 0,10878402 ! pigment granule organization GO:0048753 16 8 0,000 0,04453544 0,10867369 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04453544 0,10856359 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04453544 0,10845371 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04453544 0,10834405 ! histidine metabolic process GO:0006547 16 8 0,000 0,04453544 0,10823461 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04453544 0,10812539 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04453544 0,10801639 ! glycine catabolic process GO:0006546 13 8 0,000 0,04453544 0,10790761 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04453544 0,10779906 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04453544 0,10769071 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04453544 0,10758259 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04453544 0,10747468 ! melanin metabolic process GO:0006582 15 8 0,000 0,04453544 0,10736699 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04453544 0,10725952 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04453544 0,10715226 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04453544 0,10704522 ! macrophage activation GO:0042116 12 8 0,000 0,04453544 0,10693838 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04453544 0,10683177 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04453544 0,10672536 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04453544 0,10661916 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04453544 0,10651318 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04453544 0,10640741 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04453544 0,10630185 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04453544 0,10619649 ! osteoblast development GO:0002076 16 8 0,000 0,04453544 0,10609135 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04453544 0,10598641 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04453544 0,10588168 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04453544 0,10577716 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04453544 0,10567284 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04453544 0,10556873 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04453544 0,10546482 ! response to UV-B GO:0010224 16 8 0,000 0,04453544 0,10536112 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04453544 0,10525762 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04453544 0,10515433 ! intermediate filament organization GO:0045109 12 8 0,000 0,04453544 0,10505124 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04453544 0,10494835 ! cellular extravasation GO:0045123 12 8 0,000 0,04453544 0,10484566 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04453544 0,10474317 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04453544 0,10464088 ! response to antibiotic GO:0046677 11 8 0,000 0,04453544 0,10453879 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04453544 0,1044369 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04453544 0,10433521 ! DNA topological change GO:0006265 12 8 0,000 0,04453544 0,10423372 ! response to tropane GO:0014073 15 8 0,000 0,04453544 0,10413242 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04453544 0,10403132 ! melanosome transport GO:0032402 13 8 0,000 0,04453544 0,10393042 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04453544 0,10382971 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04453544 0,1037292 ! mast cell activation GO:0045576 14 8 0,000 0,04453544 0,10362888 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04453544 0,10352875 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04453544 0,10342882 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04453544 0,10332908 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04453544 0,10322954 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04453544 0,10313018 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04453544 0,10303102 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04453544 0,10293205 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04453544 0,10283326 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04453544 0,10273467 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04453544 0,10263627 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04453544 0,10253805 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04453544 0,10244002 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04453544 0,10234218 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04453544 0,10224452 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04453544 0,10214706 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04453544 0,10204977 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04453544 0,10195267 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04453544 0,10185576 ! hormone catabolic process GO:0042447 17 8 0,000 0,04453544 0,10175903 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04453544 0,10166249 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04453544 0,10156612 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04453544 0,10146994 ! ATP catabolic process GO:0006200 11 8 0,000 0,04453544 0,10137395 ! blastocyst growth GO:0001832 19 8 0,000 0,04453544 0,10127813 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04453544 0,10118249 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04453544 0,10108704 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04453544 0,10099176 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04453544 0,10089667 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04453544 0,10080175 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04453544 0,10070701 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04453544 0,10061245 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04453544 0,10051807 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04453544 0,10042386 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04453544 0,10032983 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04453544 0,10023598 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04453544 0,1001423 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04453544 0,1000488 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04453544 0,09995547 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04453544 0,09986231 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04453544 0,09976933 ! mesoderm development GO:0007498 119 61 1,000 0,04715269 0,10553429 ! regulation of mitosis GO:0007088 105 63 1,000 0,04995632 0,1117053 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04995632 0,11160158 ! detection of external stimulus GO:0009581 91 63 1,000 0,04995632 0,11149806 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04996187 0,1114071 ! axon extension GO:0048675 15 9 0,000 0,04996187 0,11130394 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04996187 0,11120098 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04996187 0,1110982 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04996187 0,11099562 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04996187 0,11089323 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04996187 0,11079102 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04996187 0,110689 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04996187 0,11058717 ! phosphate transport GO:0006817 19 9 0,000 0,04996187 0,11048553 ! reproductive behavior GO:0019098 19 9 0,000 0,04996187 0,11038407 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04996187 0,1102828 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04996187 0,11018172 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04996187 0,11008082 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04996187 0,10998011 ! GTP metabolic process GO:0046039 9 9 0,000 0,04996187 0,10987958 ! RNA methylation GO:0001510 15 9 0,000 0,04996187 0,10977923 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04996187 0,10967907 ! artery development GO:0060840 24 9 0,000 0,04996187 0,10957908 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04996187 0,10947929 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04996187 0,10937967 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04996187 0,10928023 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04996187 0,10918098 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04996187 0,1090819 ! chemosensory behavior GO:0007635 20 9 0,000 0,04996187 0,10898301 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04996187 0,10888429 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04996187 0,10878575 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04996187 0,10868739 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04996187 0,10858921 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04996187 0,10849121 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04996187 0,10839338 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04996187 0,10829573 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04996187 0,10819825 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04996187 0,10810095 ! protein targeting to ER GO:0045047 22 9 0,000 0,04996187 0,10800382 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04996187 0,10790687 ! T cell selection GO:0045058 23 9 0,000 0,04996187 0,1078101 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04996187 0,10771349 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04996187 0,10761706 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04996187 0,1075208 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04996187 0,10742471 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04996187 0,1073288 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04996187 0,10723306 ! mannose metabolic process GO:0006013 13 9 0,000 0,04996187 0,10713748 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04996187 0,10704208 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04996187 0,10694685 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04996187 0,10685178 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04996187 0,10675689 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04996187 0,10666216 ! ruffle organization GO:0031529 15 9 0,000 0,04996187 0,1065676 ! retinol metabolic process GO:0042572 18 9 0,000 0,04996187 0,10647321 ! behavioral fear response GO:0001662 22 9 0,000 0,04996187 0,10637899 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04996187 0,10628493 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04996187 0,10619104 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04996187 0,10609731 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04996187 0,10600375 ! protein heterooligomerization GO:0051291 16 9 0,000 0,04996187 0,10591036 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04996187 0,10581713 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04996187 0,10572406 ! segment specification GO:0007379 13 9 0,000 0,04996187 0,10563116 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04996187 0,10553842 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04996187 0,10544584 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04996187 0,10535342 ! response to amine stimulus GO:0014075 13 9 0,000 0,04996187 0,10526117 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04996187 0,10516908 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04996187 0,10507715 ! erythrocyte development GO:0048821 15 9 0,000 0,04996187 0,10498538 ! gas homeostasis GO:0033483 16 9 0,000 0,04996187 0,10489377 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04996187 0,10480232 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04996187 0,10471102 ! renal water homeostasis GO:0003091 14 9 0,000 0,04996187 0,10461989 ! postreplication repair GO:0006301 22 9 0,000 0,04996187 0,10452892 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04996187 0,1044381 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04996187 0,10434744 ! icosanoid secretion GO:0032309 15 9 0,000 0,04996187 0,10425694 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04996187 0,1041666 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04996187 0,10407641 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04996187 0,10398638 ! regulation of cell division GO:0051302 15 9 0,000 0,04996187 0,1038965 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04996187 0,10380678 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04996187 0,10371722 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04996187 0,10362781 ! sterol catabolic process GO:0016127 11 9 0,000 0,04996187 0,10353855 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04996187 0,10344945 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04996187 0,1033605 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04996187 0,1032717 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04996187 0,10318305 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04996187 0,10309456 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04996187 0,10300622 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04996187 0,10291803 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04996187 0,10282999 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04996187 0,1027421 ! purine base metabolic process GO:0006144 21 9 0,000 0,04996187 0,10265436 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04996187 0,10256677 ! pigment granule transport GO:0051904 17 9 0,000 0,04996187 0,10247933 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04996187 0,10239204 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04996187 0,1023049 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04996187 0,1022179 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04996187 0,10213106 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04996187 0,10204436 ! mitochondrion localization GO:0051646 15 9 0,000 0,04996187 0,10195781 ! single fertilization GO:0007338 75 64 1,000 0,05138026 0,10476348 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,05281867 0,10760518 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 1,000 0,05281867 0,10751414 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05427133 0,11037771 ! actin filament organization GO:0007015 148 66 1,000 0,05427133 0,11028448 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05535766 0,11239707 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05535766 0,1123023 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05535766 0,11220769 ! synapsis GO:0007129 13 10 0,000 0,05535766 0,11211324 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05535766 0,11201895 ! N-glycan processing GO:0006491 20 10 0,000 0,05535766 0,11192482 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05535766 0,11183084 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05535766 0,11173702 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05535766 0,11164336 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05535766 0,11154986 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05535766 0,11145651 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05535766 0,11136332 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05535766 0,11127029 ! androgen metabolic process GO:0008209 17 10 0,000 0,05535766 0,11117741 ! phospholipid efflux GO:0033700 16 10 0,000 0,05535766 0,11108468 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05535766 0,11099211 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05535766 0,11089969 ! pathogenesis GO:0009405 13 10 0,000 0,05535766 0,11080743 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05535766 0,11071532 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05535766 0,11062337 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05535766 0,11053156 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05535766 0,11043991 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05535766 0,11034841 ! endoderm development GO:0007492 16 10 0,000 0,05535766 0,11025706 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05535766 0,11016587 ! arginine catabolic process GO:0006527 13 10 0,000 0,05535766 0,11007482 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05535766 0,10998392 ! proline metabolic process GO:0006560 13 10 0,000 0,05535766 0,10989318 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05535766 0,10980258 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05535766 0,10971214 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05535766 0,10962184 ! V(D)J recombination GO:0033151 28 10 0,000 0,05535766 0,10953169 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05535766 0,10944169 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05535766 0,10935183 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05535766 0,10926213 ! B cell proliferation GO:0042100 18 10 0,000 0,05535766 0,10917257 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05535766 0,10908316 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05535766 0,10899389 ! multicellular organism growth GO:0035264 18 10 0,000 0,05535766 0,10890477 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05535766 0,10881579 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05535766 0,10872697 ! epithelial cell development GO:0002064 20 10 0,000 0,05535766 0,10863828 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05535766 0,10854974 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05535766 0,10846135 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05535766 0,10837309 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05535766 0,10828499 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05535766 0,10819702 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05535766 0,1081092 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05535766 0,10802152 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05535766 0,10793398 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05535766 0,10784659 ! brain morphogenesis GO:0048854 23 10 0,000 0,05535766 0,10775933 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05535766 0,10767222 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05535766 0,10758524 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05535766 0,10749841 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05535766 0,10741172 ! response to dsRNA GO:0043331 20 10 0,000 0,05535766 0,10732517 ! DNA ligation GO:0006266 19 10 0,000 0,05535766 0,10723875 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05535766 0,10715248 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05535766 0,10706634 ! melanosome localization GO:0032400 16 10 0,000 0,05535766 0,10698035 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05535766 0,10689449 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05535766 0,10680877 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05535766 0,10672318 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05535766 0,10663774 ! mRNA cleavage GO:0006379 17 10 0,000 0,05535766 0,10655243 ! protein sumoylation GO:0016925 15 10 0,000 0,05535766 0,10646725 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05535766 0,10638221 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05535766 0,10629731 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05535766 0,10621255 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05535766 0,10612791 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05535766 0,10604342 ! salivary gland development GO:0007431 27 10 0,000 0,05535766 0,10595906 ! prophase GO:0051324 15 10 0,000 0,05535766 0,10587483 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05535766 0,10579073 ! apical protein localization GO:0045176 15 10 0,000 0,05535766 0,10570677 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05535766 0,10562294 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05535766 0,10553925 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05535766 0,10545569 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05535766 0,10537226 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05535766 0,10528896 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05535766 0,10520579 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05535766 0,10512276 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05535766 0,10503985 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05535766 0,10495708 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05535766 0,10487444 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05535766 0,10479192 ! oocyte development GO:0048599 17 10 0,000 0,05535766 0,10470954 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05535766 0,10462728 ! blastocyst formation GO:0001825 17 10 0,000 0,05535766 0,10454516 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05535766 0,10446316 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05535766 0,1043813 ! activation of innate immune response GO:0002218 12 10 0,000 0,05535766 0,10429956 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05535766 0,10421794 ! response to nicotine GO:0035094 20 10 0,000 0,05535766 0,10413646 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05535766 0,1040551 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05535766 0,10397387 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05535766 0,10389277 ! lung development GO:0030324 144 67 1,000 0,05573805 0,10452514 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,05721862 0,10721808 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05871284 0,10993237 ! appendage morphogenesis GO:0035107 135 70 1,000 0,0602205 0,1126676 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,0602205 0,11258006 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06072299 0,11343129 ! respiratory burst GO:0045730 17 11 0,000 0,06072299 0,11334329 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06072299 0,11325543 ! neuron fate specification GO:0048665 17 11 0,000 0,06072299 0,1131677 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06072299 0,11308011 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06072299 0,11299266 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06072299 0,11290534 ! thyroid gland development GO:0030878 26 11 0,000 0,06072299 0,11281815 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06072299 0,1127311 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06072299 0,11264418 ! response to pain GO:0048265 24 11 0,000 0,06072299 0,1125574 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06072299 0,11247075 ! T cell proliferation GO:0042098 26 11 0,000 0,06072299 0,11238423 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06072299 0,11229785 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06072299 0,1122116 ! bone resorption GO:0045453 16 11 0,000 0,06072299 0,11212548 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06072299 0,1120395 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06072299 0,11195364 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06072299 0,11186792 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06072299 0,11178233 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06072299 0,11169687 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06072299 0,11161154 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06072299 0,11152634 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06072299 0,11144127 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06072299 0,11135633 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06072299 0,11127152 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06072299 0,11118684 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06072299 0,11110228 ! UV protection GO:0009650 19 11 0,000 0,06072299 0,11101786 ! adult heart development GO:0007512 14 11 0,000 0,06072299 0,11093356 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06072299 0,1108494 ! temperature homeostasis GO:0001659 17 11 0,000 0,06072299 0,11076536 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06072299 0,11068144 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06072299 0,11059766 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06072299 0,110514 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06072299 0,11043046 ! regulation of organ growth GO:0046620 13 11 0,000 0,06072299 0,11034706 ! pigment granule localization GO:0051875 20 11 0,000 0,06072299 0,11026378 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06072299 0,11018062 ! vasoconstriction GO:0042310 18 11 0,000 0,06072299 0,11009759 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06072299 0,11001469 ! embryonic axis specification GO:0000578 18 11 0,000 0,06072299 0,10993191 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06072299 0,10984925 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06072299 0,10976672 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06072299 0,10968431 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06072299 0,10960203 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06072299 0,10951987 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06072299 0,10943783 ! zymogen activation GO:0031638 15 11 0,000 0,06072299 0,10935592 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06072299 0,10927412 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06072299 0,10919245 ! nucleosome positioning GO:0016584 15 11 0,000 0,06072299 0,10911091 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06072299 0,10902948 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06072299 0,10894818 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06072299 0,10886699 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06072299 0,10878593 ! acid secretion GO:0046717 18 11 0,000 0,06072299 0,10870499 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06072299 0,10862417 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06072299 0,10854347 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06072299 0,10846288 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06072299 0,10838242 ! oocyte differentiation GO:0009994 18 11 0,000 0,06072299 0,10830208 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06072299 0,10822186 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06072299 0,10814175 ! cholesterol efflux GO:0033344 19 11 0,000 0,06072299 0,10806176 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06072299 0,1079819 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06072299 0,10790215 ! germ cell migration GO:0008354 25 11 0,000 0,06072299 0,10782251 ! embryonic gut development GO:0048566 15 11 0,000 0,06072299 0,107743 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06072299 0,1076636 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06072299 0,10758432 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06072299 0,10750515 ! defense response to fungus GO:0050832 13 11 0,000 0,06072299 0,10742611 ! developmental induction GO:0031128 19 11 0,000 0,06072299 0,10734717 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06072299 0,10726836 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06072299 0,10718966 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06072299 0,10711107 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06072299 0,1070326 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06072299 0,10695425 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06072299 0,10687601 ! nucleus localization GO:0051647 19 11 0,000 0,06072299 0,10679788 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06072299 0,10671987 ! reproductive structure development GO:0048608 113 71 1,000 0,06174141 0,10843054 ! appendage development GO:0048736 136 71 1,000 0,06174141 0,10835145 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 0,06327537 0,1109625 ! respiratory system development GO:0060541 153 72 1,000 0,06327537 0,11088168 ! regulation of blood pressure GO:0008217 125 73 1,000 0,06482219 0,1135096 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,06482219 0,11342705 ! axon guidance GO:0007411 139 73 1,000 0,06482219 0,11334461 ! fertilization GO:0009566 90 73 1,000 0,06482219 0,1132623 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06605801 0,11533787 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06605801 0,11525423 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06605801 0,11517071 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06605801 0,11508732 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06605801 0,11500404 ! virus-host interaction GO:0019048 29 12 0,000 0,06605801 0,11492088 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06605801 0,11483785 ! cartilage condensation GO:0001502 20 12 0,000 0,06605801 0,11475493 ! mating GO:0007618 17 12 0,000 0,06605801 0,11467214 ! protein complex disassembly GO:0043241 27 12 0,000 0,06605801 0,11458946 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06605801 0,1145069 ! hippocampus development GO:0021766 26 12 0,000 0,06605801 0,11442447 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06605801 0,11434215 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06605801 0,11425994 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06605801 0,11417786 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06605801 0,1140959 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06605801 0,11401405 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06605801 0,11393232 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06605801 0,1138507 ! drug transport GO:0015893 16 12 0,000 0,06605801 0,11376921 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06605801 0,11368783 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06605801 0,11360656 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06605801 0,11352542 ! focal adhesion formation GO:0048041 35 12 0,000 0,06605801 0,11344439 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06605801 0,11336347 ! forebrain cell migration GO:0021885 21 12 0,000 0,06605801 0,11328267 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06605801 0,11320198 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06605801 0,11312141 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06605801 0,11304096 ! entry into host cell GO:0030260 32 12 0,000 0,06605801 0,11296061 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06605801 0,11288039 ! monoamine transport GO:0015844 18 12 0,000 0,06605801 0,11280027 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06605801 0,11272027 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06605801 0,11264039 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06605801 0,11256061 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06605801 0,11248095 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06605801 0,1124014 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06605801 0,11232197 ! protein homotetramerization GO:0051289 21 12 0,000 0,06605801 0,11224264 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06605801 0,11216343 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06605801 0,11208433 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06605801 0,11200534 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06605801 0,11192647 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06605801 0,1118477 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06605801 0,11176905 ! cranial nerve development GO:0021545 20 12 0,000 0,06605801 0,1116905 ! fucose catabolic process GO:0019317 22 12 0,000 0,06605801 0,11161207 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06605801 0,11153374 ! histone acetylation GO:0016573 26 12 0,000 0,06605801 0,11145553 ! histone methylation GO:0016571 26 12 0,000 0,06605801 0,11137742 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06605801 0,11129943 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06605801 0,11122154 ! gland morphogenesis GO:0022612 29 12 0,000 0,06605801 0,11114376 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06605801 0,1110661 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06605801 0,11098854 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06605801 0,11091108 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06605801 0,11083374 ! spleen development GO:0048536 22 12 0,000 0,06605801 0,1107565 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06605801 0,11067938 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06605801 0,11060235 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06605801 0,11052544 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06605801 0,11044863 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06605801 0,11037193 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06605801 0,11029534 ! response to cold GO:0009409 17 12 0,000 0,06605801 0,11021885 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06605801 0,11014247 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06605801 0,11006619 ! transition metal ion transport GO:0000041 126 74 1,000 0,06638167 0,11052892 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,06638167 0,11045248 ! organelle localization GO:0051640 136 74 1,000 0,06638167 0,11037615 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,06795362 0,11291188 ! regulation of catabolic process GO:0009894 161 76 1,000 0,06953784 0,11546449 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07113416 0,11803365 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07136292 0,11833162 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07136292 0,11825012 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07136292 0,11816874 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07136292 0,11808747 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07136292 0,11800631 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07136292 0,11792526 ! lipid localization GO:0010876 28 13 0,000 0,07136292 0,11784432 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07136292 0,1177635 ! organelle fusion GO:0048284 32 13 0,000 0,07136292 0,11768278 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07136292 0,11760218 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07136292 0,11752168 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07136292 0,1174413 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07136292 0,11736102 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07136292 0,11728086 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07136292 0,1172008 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07136292 0,11712086 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07136292 0,11704102 ! methionine metabolic process GO:0006555 27 13 0,000 0,07136292 0,11696129 ! plasma membrane organization GO:0007009 24 13 0,000 0,07136292 0,11688167 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07136292 0,11680216 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07136292 0,11672276 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07136292 0,11664346 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07136292 0,11656428 ! response to X-ray GO:0010165 25 13 0,000 0,07136292 0,1164852 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07136292 0,11640622 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07136292 0,11632736 ! exocrine system development GO:0035272 32 13 0,000 0,07136292 0,1162486 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07136292 0,11616994 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07136292 0,1160914 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07136292 0,11601296 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07136292 0,11593462 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07136292 0,1158564 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07136292 0,11577827 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07136292 0,11570025 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07136292 0,11562234 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07136292 0,11554453 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07136292 0,11546683 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07136292 0,11538923 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07136292 0,11531174 ! ribosome assembly GO:0042255 17 13 0,000 0,07136292 0,11523435 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07136292 0,11515706 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07136292 0,11507988 ! chromatin silencing GO:0006342 26 13 0,000 0,07136292 0,1150028 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07136292 0,11492582 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07136292 0,11484895 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07136292 0,11477218 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07136292 0,11469551 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07136292 0,11461894 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07136292 0,11454248 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07136292 0,11446612 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07136292 0,11438986 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07136292 0,1143137 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07136292 0,11423764 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07136292 0,11416169 ! embryonic placenta development GO:0001892 23 13 0,000 0,07136292 0,11408583 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07136292 0,11401008 ! insulin secretion GO:0030073 23 13 0,000 0,07136292 0,11393442 ! actin filament polymerization GO:0030041 24 13 0,000 0,07136292 0,11385887 ! acrosome reaction GO:0007340 18 13 0,000 0,07136292 0,11378342 ! blood coagulation GO:0007596 146 78 1,000 0,07274239 0,11590608 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07274239 0,11582938 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,07436233 0,11833054 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,07436233 0,11825233 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,07436233 0,11817422 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07599382 0,12068721 ! response to metal ion GO:0010038 140 80 1,000 0,07599382 0,1206076 ! muscle cell differentiation GO:0042692 159 80 1,000 0,07599382 0,1205281 ! rRNA transcription GO:0009303 25 14 0,000 0,07663786 0,1214695 ! lactation GO:0007595 26 14 0,000 0,07663786 0,12138953 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,07663786 0,12130967 ! reproductive cellular process GO:0048610 20 14 0,000 0,07663786 0,12122991 ! tRNA modification GO:0006400 20 14 0,000 0,07663786 0,12115026 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07663786 0,12107071 ! regulation of S phase GO:0033261 23 14 0,000 0,07663786 0,12099127 ! water transport GO:0006833 21 14 0,000 0,07663786 0,12091193 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07663786 0,1208327 ! non-recombinational repair GO:0000726 25 14 0,000 0,07663786 0,12075357 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07663786 0,12067454 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07663786 0,12059562 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07663786 0,12051679 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07663786 0,12043808 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07663786 0,12035946 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07663786 0,12028095 ! palate development GO:0060021 31 14 0,000 0,07663786 0,12020254 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07663786 0,12012423 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07663786 0,12004603 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07663786 0,11996792 ! arginine metabolic process GO:0006525 17 14 0,000 0,07663786 0,11988992 ! regulation of heart rate GO:0002027 24 14 0,000 0,07663786 0,11981202 ! organic alcohol transport GO:0015850 29 14 0,000 0,07663786 0,11973422 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07663786 0,11965652 ! embryo implantation GO:0007566 30 14 0,000 0,07663786 0,11957892 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07663786 0,11950142 ! L-amino acid transport GO:0015807 30 14 0,000 0,07663786 0,11942403 ! bone mineralization GO:0030282 17 14 0,000 0,07663786 0,11934673 ! stem cell development GO:0048864 43 14 0,000 0,07663786 0,11926953 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07663786 0,11919243 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07663786 0,11911544 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07663786 0,11903854 ! cerebellum development GO:0021549 21 14 0,000 0,07663786 0,11896174 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07663786 0,11888504 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07663786 0,11880844 ! response to gamma radiation GO:0010332 28 14 0,000 0,07663786 0,11873194 ! cofactor transport GO:0051181 26 14 0,000 0,07663786 0,11865553 ! NADP metabolic process GO:0006739 24 14 0,000 0,07663786 0,11857923 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07663786 0,11850302 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07663786 0,11842691 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07663786 0,1183509 ! oxygen transport GO:0015671 21 14 0,000 0,07663786 0,11827498 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07663786 0,11819916 ! male genitalia development GO:0030539 24 14 0,000 0,07663786 0,11812344 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07663786 0,11804782 ! regulation of axon extension GO:0030516 37 14 0,000 0,07663786 0,11797229 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07663786 0,11789686 ! digestion GO:0007586 112 81 1,000 0,07763666 0,11935706 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,07763666 0,11928084 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07929067 0,12174432 ! response to drug GO:0042493 143 82 1,000 0,07929067 0,12166668 ! response to nutrient GO:0007584 125 82 1,000 0,07929067 0,12158914 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,07929067 0,12151169 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08095569 0,12398433 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08188302 0,12532477 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08188302 0,1252451 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08188302 0,12516553 ! superoxide anion generation GO:0042554 20 15 0,000 0,08188302 0,12508606 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,08188302 0,12500669 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08188302 0,12492742 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08188302 0,12484825 ! copper ion transport GO:0006825 20 15 0,000 0,08188302 0,12476918 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08188302 0,12469022 ! sulfate transport GO:0008272 23 15 0,000 0,08188302 0,12461135 ! response to cAMP GO:0051591 22 15 0,000 0,08188302 0,12453258 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08188302 0,12445391 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08188302 0,12437534 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08188302 0,12429687 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08188302 0,1242185 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! response to hexose stimulus GO:0009746 22 15 0,000 0,08188302 0,12414023 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08188302 0,12406205 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08188302 0,12398398 ! pituitary gland development GO:0021983 29 15 0,000 0,08188302 0,123906 ! vesicle coating GO:0006901 33 15 0,000 0,08188302 0,12382812 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08188302 0,12375034 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08188302 0,12367266 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08188302 0,12359507 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08188302 0,12351758 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08188302 0,12344019 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08188302 0,12336289 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08188302 0,12328569 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08188302 0,12320859 ! histone deacetylation GO:0016575 20 15 0,000 0,08188302 0,12313159 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08188302 0,12305468 ! tissue regeneration GO:0042246 26 15 0,000 0,08188302 0,12297787 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08188302 0,12290115 ! water homeostasis GO:0030104 27 15 0,000 0,08188302 0,12282453 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08188302 0,122748 ! muscle maintenance GO:0046716 26 15 0,000 0,08188302 0,12267157 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08188302 0,12259523 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08188302 0,12251899 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08188302 0,12244285 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08188302 0,1223668 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08188302 0,12229084 ! detection of bacterium GO:0016045 18 15 0,000 0,08188302 0,12221498 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08188302 0,12213921 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08188302 0,12206353 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08188302 0,12198795 ! peptide hormone processing GO:0016486 23 15 0,000 0,08188302 0,12191246 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08263152 0,1229508 ! hemostasis GO:0007599 158 84 1,000 0,08263152 0,12287481 ! regulation of ligase activity GO:0051340 142 84 1,000 0,08263152 0,12279891 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,08263152 0,12272311 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,084318 0,1251506 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,08601496 0,12759063 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08709855 0,12911837 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08709855 0,12903886 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08709855 0,12895946 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08709855 0,12888014 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08709855 0,12880093 ! bone remodeling GO:0046849 27 16 0,000 0,08709855 0,12872182 ! filopodium assembly GO:0046847 32 16 0,000 0,08709855 0,1286428 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08709855 0,12856387 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08709855 0,12848505 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08709855 0,12840632 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08709855 0,12832769 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08709855 0,12824915 ! startle response GO:0001964 28 16 0,000 0,08709855 0,12817071 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08709855 0,12809237 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08709855 0,12801412 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08709855 0,12793597 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08709855 0,12785791 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08709855 0,12777995 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08709855 0,12770208 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08709855 0,12762431 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08709855 0,12754663 ! response to osmotic stress GO:0006970 25 16 0,000 0,08709855 0,12746905 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08709855 0,12739156 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08709855 0,12731416 ! fructose metabolic process GO:0006000 25 16 0,000 0,08709855 0,12723686 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08709855 0,12715966 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08709855 0,12708254 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08709855 0,12700552 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08709855 0,1269286 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08709855 0,12685176 ! axon cargo transport GO:0008088 43 16 0,000 0,08709855 0,12677502 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08709855 0,12669838 ! DNA replication initiation GO:0006270 27 16 0,000 0,08709855 0,12662182 ! neuron recognition GO:0008038 35 16 0,000 0,08709855 0,12654536 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08709855 0,12646899 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08709855 0,12639271 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08709855 0,12631653 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08709855 0,12624043 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08709855 0,12616443 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08709855 0,12608852 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08709855 0,1260127 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08709855 0,12593697 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08709855 0,12586133 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08709855 0,12578578 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08709855 0,12571033 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08709855 0,12563496 ! defense response to virus GO:0051607 37 16 0,000 0,08709855 0,12555969 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08772222 0,12638303 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 206 88 1,000 0,08943961 0,12878019 ! regulation of neurological system process GO:0031644 148 88 1,000 0,08943961 0,12870317 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09228463 0,13271776 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09228463 0,13263848 ! metencephalon development GO:0022037 30 17 0,000 0,09228463 0,1325593 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09228463 0,1324802 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09228463 0,1324012 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09228463 0,1323223 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09228463 0,13224349 ! glial cell development GO:0021782 27 17 0,000 0,09228463 0,13216477 ! limbic system development GO:0021761 36 17 0,000 0,09228463 0,13208615 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09228463 0,13200762 ! adult walking behavior GO:0007628 33 17 0,000 0,09228463 0,13192919 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09228463 0,13185084 ! heart looping GO:0001947 30 17 0,000 0,09228463 0,13177259 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09228463 0,13169444 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09228463 0,13161637 ! myoblast differentiation GO:0045445 45 17 0,000 0,09228463 0,1315384 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09228463 0,13146052 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09228463 0,13138273 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09228463 0,13130504 ! glycine metabolic process GO:0006544 28 17 0,000 0,09228463 0,13122743 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09228463 0,13114992 ! NAD metabolic process GO:0019674 29 17 0,000 0,09228463 0,1310725 ! membrane budding GO:0006900 37 17 0,000 0,09228463 0,13099517 ! DNA integration GO:0015074 29 17 0,000 0,09228463 0,13091794 ! regulation of protein binding GO:0043393 33 17 0,000 0,09228463 0,13084079 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09228463 0,13076373 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09228463 0,13068677 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09228463 0,13060989 ! genitalia development GO:0048806 30 17 0,000 0,09228463 0,13053311 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09228463 0,13045642 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09228463 0,13037981 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09228463 0,1303033 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09228463 0,13022687 ! steroid catabolic process GO:0006706 31 17 0,000 0,09228463 0,13015054 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09228463 0,13007429 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09228463 0,12999814 ! gas transport GO:0015669 25 17 0,000 0,09228463 0,12992207 ! organic cation transport GO:0015695 31 17 0,000 0,09228463 0,12984609 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09228463 0,1297702 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,09228463 0,1296944 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09228463 0,12961869 ! microspike assembly GO:0030035 36 17 0,000 0,09228463 0,12954307 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09228463 0,12946753 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09228463 0,12939209 ! ossification GO:0001503 188 90 1,000 0,09290412 0,1301848 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09290412 0,13010903 ! sex differentiation GO:0007548 145 90 1,000 0,09290412 0,13003334 ! bone development GO:0060348 189 91 1,000 0,0946509 0,1324012 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09744142 0,13622548 ! neuron maturation GO:0042551 42 18 0,000 0,09744142 0,13614637 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09744142 0,13606735 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09744142 0,13598843 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09744142 0,1359096 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09744142 0,13583085 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09744142 0,1357522 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09744142 0,13567364 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09744142 0,13559517 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09744142 0,13551679 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09744142 0,13543851 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09744142 0,13536031 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09744142 0,1352822 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09744142 0,13520418 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09744142 0,13512626 ! response to retinoic acid GO:0032526 26 18 0,000 0,09744142 0,13504842 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,09744142 0,13497067 ! response to fungus GO:0009620 21 18 0,000 0,09744142 0,13489301 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09744142 0,13481544 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09744142 0,13473796 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09744142 0,13466057 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09744142 0,13458327 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09744142 0,13450605 ! vitamin transport GO:0051180 27 18 0,000 0,09744142 0,13442893 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09744142 0,13435189 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09744142 0,13427494 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09744142 0,13419808 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09744142 0,13412131 ! nerve development GO:0021675 28 18 0,000 0,09744142 0,13404463 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09744142 0,13396803 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09817271 0,13489637 ! regulation of membrane potential GO:0042391 164 93 1,000 0,09817271 0,13481937 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,09817271 0,13474246 ! protein secretion GO:0009306 39 19 0,000 0,10256908 0,14069624 ! positive regulation of translation GO:0045727 30 19 0,000 0,10256908 0,14061607 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10256908 0,140536 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10256908 0,14045601 ! skin development GO:0043588 36 19 0,000 0,10256908 0,14037611 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10256908 0,14029631 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10256908 0,1402166 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10256908 0,14013697 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10256908 0,14005744 ! cerebral cortex development GO:0021987 36 19 0,000 0,10256908 0,139978 ! response to vitamin A GO:0033189 27 19 0,000 0,10256908 0,13989864 ! heme metabolic process GO:0042168 36 19 0,000 0,10256908 0,13981938 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10256908 0,13974021 ! neuromuscular junction development GO:0007528 34 19 0,000 0,10256908 0,13966113 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10256908 0,13958213 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10256908 0,13950323 ! peptide cross-linking GO:0018149 37 19 0,000 0,10256908 0,13942441 ! protein export from nucleus GO:0006611 36 19 0,000 0,10256908 0,13934569 ! heart process GO:0003015 30 19 0,000 0,10256908 0,13926705 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10256908 0,1391885 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10256908 0,13911004 ! visual learning GO:0008542 36 19 0,000 0,10256908 0,13903167 ! cellular pigmentation GO:0033059 36 19 0,000 0,10256908 0,13895338 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10256908 0,13887519 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10256908 0,13879708 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10256908 0,13871906 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10256908 0,13864113 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10256908 0,13856328 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10256908 0,13848553 ! cilium assembly GO:0042384 37 19 0,000 0,10256908 0,13840786 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10256908 0,13833027 ! detection of stimulus GO:0051606 151 96 1,000 0,10352361 0,13953939 ! response to virus GO:0009615 160 98 1,000 0,1071345 0,14432565 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10766778 0,14496289 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10766778 0,14488181 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10766778 0,14480083 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,10766778 0,14471993 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10766778 0,14463913 ! response to vitamin GO:0033273 31 20 0,000 0,10766778 0,14455842 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10766778 0,14447779 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10766778 0,14439726 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10766778 0,14431681 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10766778 0,14423646 ! response to alkaloid GO:0043279 38 20 0,000 0,10766778 0,14415619 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10766778 0,14407602 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10766778 0,14399593 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10766778 0,14391593 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10766778 0,14383603 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10766778 0,14375621 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10766778 0,14367647 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10766778 0,14359683 ! body fluid secretion GO:0007589 31 20 0,000 0,10766778 0,14351728 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10766778 0,14343781 ! peptide secretion GO:0002790 35 20 0,000 0,10766778 0,14335843 ! stem cell differentiation GO:0048863 53 20 0,000 0,10766778 0,14327914 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10766778 0,14319993 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10766778 0,14312082 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10766778 0,14304179 ! sensory perception of pain GO:0019233 30 20 0,000 0,10766778 0,14296285 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10766778 0,14288399 ! diencephalon development GO:0021536 34 20 0,000 0,10766778 0,14280523 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10766778 0,14272655 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10766778 0,14264795 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10766778 0,14256945 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,10766778 0,14249102 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10766778 0,14241269 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10766778 0,14233444 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10766778 0,14225628 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10766778 0,1421782 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10766778 0,14210021 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10766778 0,1420223 ! actin filament-based movement GO:0030048 43 20 0,000 0,10766778 0,14194448 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10766778 0,14186675 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10766778 0,1417891 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10766778 0,14171153 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10766778 0,14163405 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,10895257 0,14324583 ! regulation of cell killing GO:0031341 42 21 0,000 0,11273768 0,14814138 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11273768 0,14806052 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11273768 0,14797974 ! hormone secretion GO:0046879 38 21 0,000 0,11273768 0,14789905 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11273768 0,14781845 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11273768 0,14773794 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11273768 0,14765752 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11273768 0,14757718 ! axis specification GO:0009798 38 21 0,000 0,11273768 0,14749694 ! ovarian follicle development GO:0001541 35 21 0,000 0,11273768 0,14741677 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11273768 0,1473367 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11273768 0,14725671 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11273768 0,14717681 ! cell aging GO:0007569 44 21 0,000 0,11273768 0,147097 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11273768 0,14701727 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11273768 0,14693763 ! cytolysis GO:0019835 24 21 0,000 0,11273768 0,14685807 ! vasodilation GO:0042311 39 21 0,000 0,11273768 0,14677861 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11273768 0,14669922 ! oogenesis GO:0048477 36 21 0,000 0,11273768 0,14661993 ! DNA modification GO:0006304 34 21 0,000 0,11273768 0,14654072 ! collagen fibril organization GO:0030199 59 21 0,000 0,11273768 0,14646159 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11273768 0,14638255 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11273768 0,14630359 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11273768 0,14622472 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11273768 0,14614594 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11273768 0,14606724 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11273768 0,14598862 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11273768 0,14591009 ! collagen catabolic process GO:0030574 28 21 0,000 0,11273768 0,14583165 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11273768 0,14575329 ! gut development GO:0048565 39 21 0,000 0,11273768 0,14567501 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11777895 0,15210743 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11777895 0,15202583 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11777895 0,15194431 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11777895 0,15186288 ! microtubule-based transport GO:0010970 54 22 0,000 0,11777895 0,15178154 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11777895 0,15170029 ! regeneration GO:0031099 41 22 0,000 0,11777895 0,15161912 ! keratinization GO:0031424 28 22 0,000 0,11777895 0,15153804 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11777895 0,15145705 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11777895 0,15137614 ! sensory perception of taste GO:0050909 28 22 0,000 0,11777895 0,15129532 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11777895 0,15121459 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11777895 0,15113394 ! vacuolar transport GO:0007034 36 22 0,000 0,11777895 0,15105338 ! lysosome organization GO:0007040 41 22 0,000 0,11777895 0,15097291 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11777895 0,15089251 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11777895 0,15081221 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11777895 0,15073199 ! fucose metabolic process GO:0006004 39 22 0,000 0,11777895 0,15065186 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11777895 0,15057181 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11777895 0,15049184 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11777895 0,15041197 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11777895 0,15033217 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11777895 0,15025246 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11777895 0,15017284 ! sarcomere organization GO:0045214 30 22 0,000 0,11777895 0,1500933 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11777895 0,15001384 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11777895 0,14993447 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11777895 0,14985518 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11777895 0,14977597 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,12279173 0,1560681 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12279173 0,1559857 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,12279173 0,15590338 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12279173 0,15582115 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12279173 0,15573901 ! gluconeogenesis GO:0006094 33 23 0,000 0,12279173 0,15565696 ! viral genome replication GO:0019079 41 23 0,000 0,12279173 0,15557499 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12279173 0,15549311 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12279173 0,15541131 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12279173 0,1553296 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12279173 0,15524798 ! visual behavior GO:0007632 42 23 0,000 0,12279173 0,15516644 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12279173 0,15508499 ! response to ethanol GO:0045471 46 23 0,000 0,12279173 0,15500362 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12279173 0,15492234 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,12279173 0,15484115 ! peroxisome organization GO:0007031 37 23 0,000 0,12279173 0,15476003 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12279173 0,15467901 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12279173 0,15459807 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12279173 0,15451721 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12279173 0,15443644 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,12279173 0,15435575 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12279173 0,15427515 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12279173 0,15419463 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12279173 0,15411419 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12279173 0,15403384 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12279173 0,15395357 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12279173 0,15387339 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12279173 0,15379329 ! fatty acid transport GO:0015908 44 23 0,000 0,12279173 0,15371327 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12279173 0,15363334 ! hormone transport GO:0009914 40 23 0,000 0,12279173 0,15355349 ! cell-cell recognition GO:0009988 25 23 0,000 0,12279173 0,15347372 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12279173 0,15339403 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12279173 0,15331443 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12279173 0,15323491 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12279173 0,15315547 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,1277762 0,15928992 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1277762 0,15920743 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,1277762 0,15912502 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1277762 0,1590427 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1277762 0,15896047 ! vesicle docking GO:0048278 47 24 0,000 0,1277762 0,15887831 ! spinal cord development GO:0021510 47 24 0,000 0,1277762 0,15879625 ! vacuole organization GO:0007033 43 24 0,000 0,1277762 0,15871427 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1277762 0,15863237 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1277762 0,15855056 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,1277762 0,15846883 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1277762 0,15838719 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1277762 0,15830563 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1277762 0,15822416 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1277762 0,15814277 ! membrane depolarization GO:0051899 39 24 0,000 0,1277762 0,15806146 ! pallium development GO:0021543 49 24 0,000 0,1277762 0,15798024 ! pentose metabolic process GO:0019321 35 24 0,000 0,1277762 0,1578991 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1277762 0,15781804 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1277762 0,15773706 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1277762 0,15765617 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1277762 0,15757537 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1277762 0,15749464 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1277762 0,157414 ! regulation of amine transport GO:0051952 40 24 0,000 0,1277762 0,15733344 ! protein tetramerization GO:0051262 52 24 0,000 0,1277762 0,15725296 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13273251 0,16326913 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13273251 0,1631857 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13273251 0,16310236 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13273251 0,1630191 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,13273251 0,16293593 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13273251 0,16285284 ! sperm motility GO:0030317 31 25 0,000 0,13273251 0,16276984 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13273251 0,16268692 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,13273251 0,16260409 ! chromosome condensation GO:0030261 45 25 0,000 0,13273251 0,16252134 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13273251 0,16243867 ! neural crest cell development GO:0014032 54 25 0,000 0,13273251 0,16235609 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13273251 0,16227359 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13273251 0,16219118 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13273251 0,16210884 ! interaction with host GO:0051701 62 25 0,000 0,13273251 0,1620266 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13273251 0,16194443 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,13273251 0,16186235 ! immunoglobulin production GO:0002377 55 25 0,000 0,13273251 0,16178036 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13273251 0,16169844 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13273251 0,16161661 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13273251 0,16153486 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13273251 0,1614532 ! telomere organization GO:0032200 43 25 0,000 0,13273251 0,16137161 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13273251 0,16129011 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13273251 0,16120869 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13766082 0,16710996 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13766082 0,16702569 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13766082 0,1669415 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13766082 0,1668574 ! initiation of viral infection GO:0019059 57 26 0,000 0,13766082 0,16677338 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13766082 0,16668945 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13766082 0,1666056 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13766082 0,16652184 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13766082 0,16643816 ! molting cycle process GO:0022404 50 26 0,000 0,13766082 0,16635457 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,13766082 0,16627105 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13766082 0,16618763 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13766082 0,16610428 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13766082 0,16602102 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13766082 0,16593785 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13766082 0,16585475 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13766082 0,16577174 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13766082 0,16568881 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13766082 0,16560597 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13766082 0,16552321 ! blastocyst development GO:0001824 49 26 0,000 0,13766082 0,16544053 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13766082 0,16535793 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13766082 0,16527542 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13766082 0,16519299 ! neuron fate commitment GO:0048663 48 27 0,000 0,14256129 0,17098827 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14256129 0,17090307 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14256129 0,17081796 ! iron ion transport GO:0006826 59 27 0,000 0,14256129 0,17073294 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14256129 0,17064799 ! protein amino acid acylation GO:0043543 55 27 0,000 0,14256129 0,17056314 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14256129 0,17047836 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14256129 0,17039368 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14256129 0,17030907 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14256129 0,17022455 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14256129 0,17014011 ! male gonad development GO:0008584 44 27 0,000 0,14256129 0,17005576 ! response to toxin GO:0009636 47 27 0,000 0,14256129 0,16997149 ! primary neural tube formation GO:0014020 51 27 0,000 0,14256129 0,1698873 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14256129 0,1698032 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14256129 0,16971918 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14256129 0,16963525 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14256129 0,16955139 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14256129 0,16946762 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14256129 0,16938393 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14743407 0,17508706 ! circadian rhythm GO:0007623 50 28 0,000 0,14743407 0,17500068 ! dendrite development GO:0016358 59 28 0,000 0,14743407 0,17491439 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14743407 0,17482818 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14743407 0,17474206 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14743407 0,17465602 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14743407 0,17457007 ! lipid oxidation GO:0034440 43 28 0,000 0,14743407 0,1744842 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14743407 0,17439842 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14743407 0,17431272 ! translational initiation GO:0006413 65 29 0,000 0,15227933 0,17995288 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15227933 0,17986453 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15227933 0,17977628 ! regulation of pH GO:0006885 43 29 0,000 0,15227933 0,17968811 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,15227933 0,17960003 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15227933 0,17951203 ! catechol metabolic process GO:0009712 54 29 0,000 0,15227933 0,17942412 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15227933 0,1793363 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15227933 0,17924856 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15227933 0,17916091 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15227933 0,17907334 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15227933 0,17898586 ! cell fate determination GO:0001709 60 29 0,000 0,15227933 0,17889847 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15227933 0,17881116 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15227933 0,17872393 ! tissue homeostasis GO:0001894 48 29 0,000 0,15227933 0,17863679 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15227933 0,17854974 ! phenol metabolic process GO:0018958 55 30 0,000 0,1570972 0,18410904 ! membrane docking GO:0022406 61 30 0,000 0,1570972 0,18401941 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1570972 0,18392986 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1570972 0,1838404 ! acute-phase response GO:0006953 49 30 0,000 0,1570972 0,18375103 ! myofibril assembly GO:0030239 47 30 0,000 0,1570972 0,18366174 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1570972 0,18357254 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,1570972 0,18348343 ! phospholipid transport GO:0015914 51 30 0,000 0,1570972 0,1833944 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1570972 0,18330546 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1570972 0,18321661 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,1570972 0,18312784 ! eye morphogenesis GO:0048592 60 30 0,000 0,1570972 0,18303916 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16188785 0,18852961 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16188785 0,1884384 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16188785 0,18834728 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16188785 0,18825625 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16188785 0,1881653 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16188785 0,18807445 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16188785 0,18798368 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16188785 0,18789299 ! ovulation cycle process GO:0022602 49 31 0,000 0,16188785 0,1878024 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16188785 0,18771189 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16188785 0,18762147 ! peptide transport GO:0015833 55 31 0,000 0,16188785 0,18753114 ! iron ion homeostasis GO:0055072 54 31 0,000 0,16188785 0,18744089 ! natural killer cell activation GO:0030101 45 31 0,000 0,16188785 0,18735073 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16188785 0,18726066 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16188785 0,18717068 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16188785 0,18708078 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16188785 0,18699096 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16665144 0,19240084 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16665144 0,19230857 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16665144 0,19221638 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16665144 0,19212427 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16665144 0,19203226 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16665144 0,19194033 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16665144 0,1918485 ! response to ionizing radiation GO:0010212 65 32 0,000 0,16665144 0,19175675 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,16665144 0,19166509 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16665144 0,19157351 ! muscle cell development GO:0055001 49 32 0,000 0,16665144 0,19148202 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16665144 0,19139062 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16665144 0,19129931 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16665144 0,19120809 ! ovulation cycle GO:0042698 51 32 0,000 0,16665144 0,19111695 ! peripheral nervous system development GO:0007422 64 32 0,000 0,16665144 0,1910259 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,16665144 0,19093493 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16665144 0,19084405 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,16665144 0,19075326 ! gene silencing GO:0016458 65 32 0,000 0,16665144 0,19066256 ! post-embryonic development GO:0009791 69 33 0,000 0,1713881 0,19598849 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,1713881 0,19589538 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1713881 0,19580236 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1713881 0,19570943 ! cell fate specification GO:0001708 52 33 0,000 0,1713881 0,19561659 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1713881 0,19552384 ! adult locomotory behavior GO:0008344 59 33 0,000 0,1713881 0,19543117 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,1713881 0,1953386 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,176098 0,20061165 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,176098 0,2005167 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,176098 0,20042185 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,176098 0,20032709 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,176098 0,20023242 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,176098 0,20013784 ! mismatch repair GO:0006298 46 34 0,000 0,176098 0,20004334 ! spermatid development GO:0007286 63 34 0,000 0,176098 0,19994894 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,176098 0,19985462 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,176098 0,19976039 ! placenta development GO:0001890 53 34 0,000 0,176098 0,19966626 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,176098 0,19957221 ! regulation of muscle development GO:0048634 70 35 0,000 0,18078129 0,20478332 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18078129 0,20468696 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18078129 0,20459068 ! female gonad development GO:0008585 58 35 0,000 0,18078129 0,20449449 ! telencephalon development GO:0021537 68 35 0,000 0,18078129 0,20439839 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18078129 0,20430239 ! cytokine production GO:0001816 59 35 0,000 0,18078129 0,20420647 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18078129 0,20411064 ! neural tube formation GO:0001841 67 35 0,000 0,18078129 0,20401491 ! vesicle localization GO:0051648 64 35 0,000 0,18078129 0,20391926 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18543811 0,20907408 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18543811 0,20897615 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18543811 0,20887832 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18543811 0,20878057 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18543811 0,20868292 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18543811 0,20858536 ! aerobic respiration GO:0009060 55 36 0,000 0,18543811 0,20848789 ! embryonic organ development GO:0048568 57 36 0,000 0,18543811 0,20839051 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18543811 0,20829322 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19006861 0,21339481 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19006861 0,21329527 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19006861 0,21319584 ! organic anion transport GO:0015711 68 37 0,000 0,19006861 0,21309649 ! tissue remodeling GO:0048771 76 37 0,000 0,19006861 0,21299724 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19006861 0,21289808 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19006861 0,21279901 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19006861 0,21270003 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,19006861 0,21260115 ! pigment metabolic process GO:0042440 80 37 0,000 0,19006861 0,21250235 ! spermatid differentiation GO:0048515 66 37 0,000 0,19006861 0,21240365 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19467294 0,21744804 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,19467294 0,21734714 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19467294 0,21724633 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19467294 0,21714561 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19467294 0,21704499 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,19467294 0,21694446 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,19467294 0,21684402 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19467294 0,21674368 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19467294 0,21664343 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19467294 0,21654327 ! glucan metabolic process GO:0044042 62 38 0,000 0,19467294 0,2164432 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,19925125 0,22143118 ! mammary gland development GO:0030879 86 39 0,000 0,19925125 0,22132895 ! ear morphogenesis GO:0042471 60 39 0,000 0,19925125 0,22122681 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,19925125 0,22112477 ! segmentation GO:0035282 67 39 0,000 0,19925125 0,22102282 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19925125 0,22092097 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,19925125 0,22081921 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,19925125 0,22071754 ! RNA modification GO:0009451 57 39 0,000 0,19925125 0,22061597 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,19925125 0,22051449 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,20380368 0,22544903 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20380368 0,22534543 ! feeding behavior GO:0007631 59 40 0,000 0,20380368 0,22524191 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,20380368 0,2251385 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20380368 0,22503518 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20833038 0,22992793 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20833038 0,22982251 ! T cell differentiation GO:0030217 81 41 0,000 0,20833038 0,22971718 ! female gamete generation GO:0007292 61 41 0,000 0,20833038 0,22961195 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,20833038 0,22950682 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,21283149 0,23435816 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21283149 0,23425095 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21283149 0,23414384 ! regulation of tube size GO:0035150 71 42 0,000 0,21283149 0,23403682 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21283149 0,23392991 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21283149 0,23382309 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21283149 0,23371637 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21283149 0,23360975 ! neuron migration GO:0001764 79 42 0,000 0,21283149 0,23350322 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21283149 0,2333968 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21730716 0,23819637 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,21730716 0,2380879 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,21730716 0,23797953 ! glucose transport GO:0015758 65 43 0,000 0,21730716 0,23787126 ! neural tube development GO:0021915 77 43 0,000 0,21730716 0,23776309 ! striated muscle contraction GO:0006941 77 43 0,000 0,21730716 0,23765502 ! phagocytosis GO:0006909 90 43 0,000 0,21730716 0,23754704 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21730716 0,23743916 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22175753 0,24219184 ! hexose transport GO:0008645 67 44 0,000 0,22175753 0,24208195 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,22175753 0,24197217 ! double-strand break repair GO:0006302 81 44 0,000 0,22175753 0,24186248 ! biopolymer methylation GO:0043414 84 44 0,000 0,22175753 0,24175289 ! B cell differentiation GO:0030183 107 44 0,000 0,22175753 0,2416434 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22175753 0,24153401 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,22175753 0,24142472 ! developmental growth GO:0048589 82 44 0,000 0,22175753 0,24131553 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22618275 0,24601975 ! glycolysis GO:0006096 65 45 0,000 0,22618275 0,24590858 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,22618275 0,24579751 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22618275 0,24568654 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22618275 0,24557567 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22618275 0,2454649 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22618275 0,24535423 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22618275 0,24524367 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23058295 0,24990206 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,23495827 0,25452931 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,23495827 0,25441476 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23495827 0,25430031 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23495827 0,25418597 ! JNK cascade GO:0007254 91 47 0,000 0,23495827 0,25407173 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,23495827 0,25395759 ! methylation GO:0032259 90 47 0,000 0,23495827 0,25384355 ! protein homooligomerization GO:0051260 76 47 0,000 0,23495827 0,25372962 ! mitochondrial transport GO:0006839 82 48 0,000 0,23930886 0,25831185 ! Notch signaling pathway GO:0007219 96 48 0,000 0,23930886 0,25819601 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,23930886 0,25808028 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,23930886 0,25796465 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,23930886 0,25784913 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,23930886 0,25773371 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24363484 0,26227536 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24363484 0,26215807 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24363484 0,26204087 ! regulation of ion transport GO:0043269 77 49 0,000 0,24363484 0,26192379 ! peptide metabolic process GO:0006518 76 49 0,000 0,24363484 0,26180681 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24363484 0,26168993 ! endocrine system development GO:0035270 104 49 0,000 0,24363484 0,26157315 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,24363484 0,26145648 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24363484 0,26133992 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 0,000 0,24793638 0,26583553 ! neuromuscular process GO:0050905 99 50 0,000 0,24793638 0,26571711 ! inner ear development GO:0048839 79 50 0,000 0,24793638 0,26559881 ! histone modification GO:0016570 91 50 0,000 0,24793638 0,26548061 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,24793638 0,26536251 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,24793638 0,26524452 ! positive regulation of binding GO:0051099 78 51 0,000 0,25221359 0,2697004 ! viral infectious cycle GO:0019058 99 51 0,000 0,25221359 0,26958058 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,25221359 0,26946087 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25221359 0,26934127 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,25221359 0,26922178 ! excretion GO:0007588 83 51 0,000 0,25221359 0,26910239 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25221359 0,26898311 ! chromatin remodeling GO:0006338 109 51 0,000 0,25221359 0,26886393 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,25221359 0,26874486 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,25221359 0,26862589 ! regulation of cell shape GO:0008360 125 51 0,000 0,25221359 0,26850703 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,25646661 0,27291405 ! positive regulation of growth GO:0045927 90 52 0,000 0,25646661 0,2727934 ! covalent chromatin modification GO:0016569 101 52 0,000 0,25646661 0,27267285 ! amino acid activation GO:0043038 92 52 0,000 0,25646661 0,27255242 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26069559 0,27692432 ! RNA catabolic process GO:0006401 93 53 0,000 0,26069559 0,27680211 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26069559 0,27668001 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26069559 0,27655802 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26069559 0,27643613 ! cell maturation GO:0048469 100 53 0,000 0,26069559 0,27631436 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,26069559 0,27619269 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26069559 0,27607112 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26490065 0,28040078 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,26490065 0,28027747 ! cell recognition GO:0008037 85 54 0,000 0,26490065 0,28015427 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26490065 0,28003118 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26490065 0,2799082 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26490065 0,27978533 ! chloride transport GO:0006821 90 55 0,000 0,26908194 0,28407685 ! glucose catabolic process GO:0006007 82 55 0,000 0,26908194 0,28395226 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,26908194 0,28382777 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26908194 0,28370339 ! RNA elongation GO:0006354 79 55 0,000 0,26908194 0,28357913 ! nuclear export GO:0051168 97 55 0,000 0,26908194 0,28345497 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27323958 0,28770872 ! sensory perception of smell GO:0007608 80 56 0,000 0,27323958 0,28758287 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,27323958 0,28745712 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27323958 0,28733148 ! proton transport GO:0015992 94 56 0,000 0,27323958 0,28720595 ! muscle fiber development GO:0048747 112 57 0,000 0,27737371 0,29142408 ! hydrogen transport GO:0006818 97 58 0,000 0,28148446 0,29561397 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28148446 0,29548499 ! adult behavior GO:0030534 99 58 0,000 0,28148446 0,29535613 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28557196 0,29951444 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,28557196 0,29938393 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28557196 0,29925354 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,28963634 0,30338051 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,28963634 0,30324849 ! camera-type eye development GO:0043010 116 60 0,000 0,28963634 0,30311659 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29367773 0,30721245 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,29367773 0,30707893 ! tRNA processing GO:0008033 89 61 0,000 0,29367773 0,30694554 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29367773 0,30681226 ! ear development GO:0043583 103 62 0,000 0,29769627 0,31087553 ! viral reproductive process GO:0022415 126 62 0,000 0,29769627 0,31074066 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29769627 0,31060591 ! gonad development GO:0008406 98 62 0,000 0,29769627 0,31047127 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,29769627 0,31033675 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,30169207 0,31436602 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30169207 0,31422993 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,30566528 0,31823049 ! cell redox homeostasis GO:0045454 102 64 0,000 0,30566528 0,31809285 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30961601 0,3220649 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,30961601 0,32192572 ! germ cell development GO:0007281 118 65 0,000 0,30961601 0,32178666 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31354439 0,32572875 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31354439 0,32558817 ! secondary metabolic process GO:0019748 116 66 0,000 0,31354439 0,32544771 ! developmental maturation GO:0021700 116 66 0,000 0,31354439 0,32530737 ! cell projection assembly GO:0030031 120 66 0,000 0,31354439 0,32516715 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,31745054 0,32907626 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,31745054 0,32893454 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,31745054 0,32879294 ! hexose catabolic process GO:0019320 104 67 0,000 0,31745054 0,32865146 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,31745054 0,32851011 ! adaptive immune response GO:0002250 119 67 0,000 0,31745054 0,32836888 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,31745054 0,32822776 ! amino acid transport GO:0006865 125 68 0,000 0,3213346 0,33210097 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3213346 0,33195837 ! viral reproduction GO:0016032 134 68 0,000 0,3213346 0,3318159 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,3213346 0,33167355 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,3213346 0,33153132 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,32519669 0,33537215 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32519669 0,33522846 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32519669 0,33508489 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32519669 0,33494145 ! amine catabolic process GO:0009310 117 71 0,000 0,33285543 0,34268299 ! humoral immune response GO:0006959 109 71 0,000 0,33285543 0,34253642 ! B cell activation GO:0042113 160 71 0,000 0,33285543 0,34238998 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,33285543 0,34224366 ! regulation of immune effector process GO:0002697 137 71 0,000 0,33285543 0,34209746 ! acute inflammatory response GO:0002526 113 72 0,000 0,33665233 0,34585205 ! carbohydrate transport GO:0008643 110 72 0,000 0,33665233 0,34570444 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,33665233 0,34555696 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,33665233 0,3454096 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3441818 0,35298441 ! exocytosis GO:0006887 133 74 0,000 0,3441818 0,35283401 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3441818 0,35268374 ! eye development GO:0001654 143 74 0,000 0,3441818 0,3525336 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34791462 0,35620535 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34791462 0,35605384 ! rhythmic process GO:0048511 128 75 0,000 0,34791462 0,35590245 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,34791462 0,3557512 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35162631 0,35939375 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,35162631 0,35924114 ! defense response to bacterium GO:0042742 89 76 0,000 0,35162631 0,35908867 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35162631 0,35893632 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35531699 0,36254991 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35531699 0,36239622 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,35531699 0,36224266 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,35898679 0,36582898 ! protein oligomerization GO:0051259 139 78 0,000 0,35898679 0,3656741 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36263583 0,36923478 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,36263583 0,36907859 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3662642 0,37261382 ! protein import into nucleus GO:0006606 158 80 0,000 0,3662642 0,37245633 ! inorganic anion transport GO:0015698 138 80 0,000 0,3662642 0,37229898 ! T cell activation GO:0042110 168 81 0,000 0,36987205 0,3758075 ! response to hypoxia GO:0001666 171 81 0,000 0,36987205 0,37564886 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36987205 0,37549036 ! nuclear import GO:0051170 161 81 0,000 0,36987205 0,37533199 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,36987205 0,37517376 ! response to oxygen levels GO:0070482 176 83 0,000 0,37702659 0,38226969 ! nucleosome assembly GO:0006334 122 85 0,000 0,38410037 0,3892778 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,38410037 0,38911389 ! amine biosynthetic process GO:0009309 138 86 0,000 0,38760726 0,39250129 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38760726 0,39233617 ! chromatin assembly GO:0031497 124 86 0,000 0,38760726 0,39217118 ! alcohol catabolic process GO:0046164 130 86 0,000 0,38760726 0,39200633 ! amine transport GO:0015837 155 86 0,000 0,38760726 0,39184163 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,3910943 0,3952007 ! protein localization in nucleus GO:0034504 176 87 0,000 0,3910943 0,39503479 ! cellular respiration GO:0045333 135 88 0,000 0,39456159 0,39836978 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39456159 0,39820268 ! cellular defense response GO:0006968 114 89 0,000 0,39800926 0,40151374 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,39800926 0,40134546 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,4014374 0,40463276 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,40484614 0,40789775 ! nucleosome organization GO:0034728 138 92 0,000 0,40823558 0,41114057 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,40823558 0,41096854 ! vitamin metabolic process GO:0006766 139 92 0,000 0,40823558 0,41079666 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,41160583 0,4140149 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,41160583 0,41384189 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,414957 0,41703698 ! female pregnancy GO:0007565 164 94 0,000 0,414957 0,41686285 ! forebrain development GO:0030900 188 95 0,000 0,41828919 0,42003497 ! leukocyte differentiation GO:0002521 202 96 0,000 0,42160251 0,4231855 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42160251 0,42300902 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42160251 0,4228327 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42160251 0,42265652 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42489707 0,4257819 ! protein ubiquitination GO:0016567 217 97 0,000 0,42489707 0,42560464 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,42817297 0,42870752 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,42817297 0,42852919 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,43143032 0,43160971 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,43143032 0,43143032 GO:0060538|skeletal muscle organ development,