pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6287-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 9,000 3,778E-13 9,229E-10 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 7,000 9,761E-11 1,192E-07 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 4,000 1,586E-09 1,291E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of phosphorylation GO:0042326 52 24 5,000 2,209E-09 1,349E-06 ! interphase of mitotic cell cycle GO:0051329 224 98 8,000 2,323E-09 1,135E-06 ! negative regulation of protein kinase activity GO:0006469 144 69 7,000 2,827E-09 1,151E-06 ! negative regulation of kinase activity GO:0033673 145 70 7,000 3,177E-09 1,109E-06 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 3,461E-09 1,057E-06 ! spindle assembly GO:0051225 6 5 3,000 3,461E-09 9,395E-07 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 3,746E-09 9,151E-07 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of transferase activity GO:0051348 155 74 7,000 4,984E-09 1,107E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,034E-08 2,105E-06 ! cellular response to extracellular stimulus GO:0031668 52 31 5,000 1,172E-08 2,203E-06 ! spindle organization GO:0007051 50 32 5,000 1,437E-08 2,507E-06 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 4,000 2,071E-08 3,373E-06 ! regulation of protein export from nucleus GO:0046825 10 7 3,000 2,403E-08 3,67E-06 ! organ growth GO:0035265 15 7 3,000 2,403E-08 3,454E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 2,403E-08 3,262E-06 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 2,403E-08 3,09E-06 ! regulation of protein stability GO:0031647 77 38 5,000 4,266E-08 5,211E-06 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 4,787E-08 5,569E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 4,787E-08 5,316E-06 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 3,000 8,582E-08 9,115E-06 ! cellular response to starvation GO:0009267 37 22 4,000 8,631E-08 8,786E-06 ! regulation of cell-matrix adhesion GO:0001952 81 23 4,000 1,098E-07 1,073E-05 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 3,000 1,425E-07 1,339E-05 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 1,425E-07 1,289E-05 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 1,425E-07 1,243E-05 GO:0042267|natural killer cell mediated cytotoxicity, ! response to starvation GO:0042594 47 27 4,000 2,591E-07 2,183E-05 ! cellular response to nutrient levels GO:0031669 45 27 4,000 2,591E-07 2,11E-05 ! negative regulation of transport GO:0051051 164 85 6,000 3,12E-07 2,459E-05 ! regulation of B cell proliferation GO:0030888 22 12 3,000 3,331E-07 2,543E-05 ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 3,331E-07 2,466E-05 ! response to heat GO:0009408 54 31 4,000 5,363E-07 3,853E-05 ! cell killing GO:0001906 32 15 3,000 9,074E-07 6,333E-05 ! negative regulation of cell adhesion GO:0007162 94 37 4,000 1,342E-06 9,104E-05 ! cardiac muscle tissue development GO:0048738 34 17 3,000 1,569E-06 1,036E-04 ! negative regulation of hormone secretion GO:0046888 26 17 3,000 1,569E-06 1,009E-04 ! endothelial cell migration GO:0043542 31 17 3,000 1,569E-06 9,83E-05 ! cell cycle checkpoint GO:0000075 145 71 5,000 1,921E-06 1,173E-04 ! positive regulation of hormone secretion GO:0046887 35 19 3,000 2,535E-06 1,511E-04 ! inositol metabolic process GO:0006020 33 19 3,000 2,535E-06 1,475E-04 ! regulation of intracellular protein transport GO:0033157 86 42 4,000 2,564E-06 1,457E-04 ! negative regulation of B cell activation GO:0050869 14 6 2,000 2,699E-06 1,498E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 3,636E-06 1,974E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 4,063E-06 2,158E-04 ! negative regulation of cell migration GO:0030336 122 46 4,000 4,063E-06 2,112E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 4,704E-06 2,394E-04 ! response to temperature stimulus GO:0009266 84 51 4,000 6,818E-06 3,399E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 7,498E-06 3,664E-04 ! regulation of insulin secretion GO:0050796 42 25 3,000 8,075E-06 3,868E-04 ! positive regulation of MAP kinase activity GO:0043406 174 93 5,000 9,305E-06 4,372E-04 ! response to UV GO:0009411 120 55 4,000 9,929E-06 4,577E-04 ! negative regulation of cell motion GO:0051271 142 55 4,000 9,929E-06 4,492E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,12E-05 4,977E-04 ! regulation of intracellular transport GO:0032386 108 57 4,000 1,185E-05 5,17E-04 ! regulation of peptide secretion GO:0002791 52 29 3,000 1,492E-05 6,394E-04 ! lipid modification GO:0030258 112 60 4,000 1,526E-05 6,43E-04 ! autophagic vacuole formation GO:0000045 17 10 2,000 1,595E-05 6,602E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,595E-05 6,492E-04 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 1,714E-05 6,866E-04 ! negative regulation of transcription regulator activity GO:0090048 57 30 3,000 1,714E-05 6,755E-04 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 3,000 1,714E-05 6,648E-04 ! cell junction assembly GO:0034329 85 31 3,000 1,96E-05 7,483E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,184E-05 8,209E-04 ! macroautophagy GO:0016236 19 11 2,000 2,184E-05 8,085E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,184E-05 7,964E-04 GO:0010829|negative regulation of glucose transport, ! BMP signaling pathway GO:0030509 71 32 3,000 2,231E-05 8,017E-04 ! triglyceride metabolic process GO:0006641 46 33 3,000 2,529E-05 8,954E-04 ! negative regulation of cell growth GO:0030308 142 67 4,000 2,621E-05 9,149E-04 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 2,901E-05 9,982E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,901E-05 9,843E-04 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell size GO:0045792 144 69 4,000 3,025E-05 1,012E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 3,025E-05 9,987E-04 ! DNA damage checkpoint GO:0000077 78 35 3,000 3,21E-05 1,046E-03 ! negative regulation of secretion GO:0051048 68 35 3,000 3,21E-05 1,032E-03 ! negative regulation of DNA binding GO:0043392 67 36 3,000 3,597E-05 1,141E-03 ! cell junction organization GO:0034330 96 37 3,000 4,016E-05 1,258E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 4,016E-05 1,242E-03 ! neutral lipid metabolic process GO:0006638 54 38 3,000 4,471E-05 1,365E-03 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 3,000 4,471E-05 1,348E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 4,763E-05 1,419E-03 ! cell-cell junction assembly GO:0007043 32 14 2,000 4,763E-05 1,402E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 4,763E-05 1,385E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 32 14 2,000 4,763E-05 1,369E-03 ! negative regulation of binding GO:0051100 71 39 3,000 4,961E-05 1,409E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 4,961E-05 1,393E-03 GO:0042593|glucose homeostasis, ! phosphoinositide metabolic process GO:0030384 146 77 4,000 5,144E-05 1,428E-03 ! glycerol ether metabolic process GO:0006662 57 40 3,000 5,491E-05 1,507E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 5,932E-05 1,61E-03 ! positive regulation of biomineral formation GO:0070169 33 15 2,000 5,932E-05 1,592E-03 ! regulation of hormone secretion GO:0046883 69 41 3,000 6,06E-05 1,609E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 6,56E-05 1,723E-03 ! organic ether metabolic process GO:0018904 59 42 3,000 6,67E-05 1,734E-03 ! heterophilic cell adhesion GO:0007157 43 16 2,000 7,273E-05 1,87E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 7,273E-05 1,851E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! hormone-mediated signaling GO:0009755 84 43 3,000 7,325E-05 1,845E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 7,372E-05 1,838E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cholesterol metabolic process GO:0008203 148 85 4,000 8,259E-05 2,038E-03 ! negative regulation of growth GO:0045926 168 85 4,000 8,259E-05 2,018E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 8,259E-05 1,998E-03 ! polyol metabolic process GO:0019751 77 45 3,000 8,772E-05 2,101E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 8,797E-05 2,087E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 8,797E-05 2,067E-03 ! regulation of protein transport GO:0051223 165 87 4,000 9,226E-05 2,147E-03 GO:0070201|regulation of establishment of protein localization, ! cell growth GO:0016049 90 46 3,000 9,569E-05 2,205E-03 ! response to unfolded protein GO:0006986 139 90 4,000 1,084E-04 2,474E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,132E-04 2,56E-03 ! cellular component disassembly GO:0022411 89 48 3,000 1,132E-04 2,537E-03 ! regulation of cell adhesion GO:0030155 241 92 4,000 1,203E-04 2,671E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 1,228E-04 2,702E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 1,329E-04 2,899E-03 ! sterol metabolic process GO:0016125 166 94 4,000 1,331E-04 2,878E-03 ! positive regulation of ossification GO:0045778 50 20 2,000 1,458E-04 3,125E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,458E-04 3,097E-03 ! cell-cell junction organization GO:0045216 43 20 2,000 1,458E-04 3,071E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,458E-04 3,045E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,458E-04 3,019E-03 ! response to protein stimulus GO:0051789 158 96 4,000 1,47E-04 3,018E-03 ! regulation of protein localization GO:0032880 188 97 4,000 1,543E-04 3,142E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 1,669E-04 3,37E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 3,000 1,669E-04 3,343E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 1,695E-04 3,366E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,695E-04 3,339E-03 ! positive regulation of osteoblast differentiation GO:0045669 52 21 2,000 1,695E-04 3,312E-03 ! regulation of multicellular organism growth GO:0040014 90 55 3,000 1,929E-04 3,74E-03 ! positive regulation of bone remodeling GO:0046852 54 22 2,000 1,955E-04 3,76E-03 GO:0034105|positive regulation of tissue remodeling, ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,955E-04 3,731E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 1,955E-04 3,702E-03 ! ureteric bud development GO:0001657 50 22 2,000 1,955E-04 3,673E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 1,955E-04 3,645E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 2,000 1,955E-04 3,618E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 2,069E-04 3,8E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 2,239E-04 4,083E-03 ! regulation of bone mineralization GO:0030500 54 23 2,000 2,239E-04 4,052E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 2,55E-04 4,58E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,638E-04 4,704E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 1,000 2,638E-04 4,67E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 2,638E-04 4,637E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,638E-04 4,604E-03 ! sister chromatid cohesion GO:0007062 15 5 1,000 2,638E-04 4,571E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,638E-04 4,539E-03 ! lipoprotein catabolic process GO:0042159 11 5 1,000 2,638E-04 4,507E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,638E-04 4,476E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,638E-04 4,445E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,638E-04 4,414E-03 ! stem cell division GO:0017145 11 5 1,000 2,638E-04 4,384E-03 GO:0048103|somatic stem cell division, ! positive regulation of secretion GO:0051047 110 61 3,000 2,881E-04 4,755E-03 ! regulation of heart contraction GO:0008016 123 61 3,000 2,881E-04 4,723E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 2,886E-04 4,701E-03 ! regulation of behavior GO:0050795 48 25 2,000 2,886E-04 4,67E-03 ! regulation of biomineral formation GO:0070167 56 25 2,000 2,886E-04 4,639E-03 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 3,067E-04 4,897E-03 ! regulation of osteoblast differentiation GO:0045667 68 26 2,000 3,25E-04 5,156E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,465E-04 5,462E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 3,643E-04 5,705E-03 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 3,678E-04 5,723E-03 ! multicellular organism reproduction GO:0032504 123 65 3,000 3,678E-04 5,686E-03 GO:0048609|reproductive process in a multicellular organism, ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 3,899E-04 5,991E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 3,944E-04 6,022E-03 ! neuron apoptosis GO:0051402 15 6 1,000 3,944E-04 5,984E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 3,944E-04 5,947E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 3,944E-04 5,911E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 3,944E-04 5,875E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 4,064E-04 6,018E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 4,064E-04 5,981E-03 ! activation of MAPK activity GO:0000187 124 67 3,000 4,13E-04 6,042E-03 ! chromosome segregation GO:0007059 127 67 3,000 4,13E-04 6,006E-03 ! autophagy GO:0006914 47 29 2,000 4,516E-04 6,528E-03 ! urogenital system development GO:0001655 149 69 3,000 4,621E-04 6,641E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 5,152E-04 7,36E-03 ! prostate gland development GO:0030850 14 7 1,000 5,502E-04 7,815E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 5,502E-04 7,77E-03 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 5,502E-04 7,725E-03 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 5,502E-04 7,681E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 5,502E-04 7,638E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 5,513E-04 7,61E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 6,028E-04 8,273E-03 ! metanephros development GO:0001656 81 32 2,000 6,061E-04 8,272E-03 ! regulation of transcription factor activity GO:0051090 137 75 3,000 6,342E-04 8,608E-03 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 3,000 6,342E-04 8,56E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 6,641E-04 8,915E-03 GO:0060326|cell chemotaxis, ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 7,257E-04 9,687E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,311E-04 9,708E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 7,311E-04 9,655E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,311E-04 9,603E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,311E-04 9,552E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 7,311E-04 9,501E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 8,089E-04 0,01045515 ! maintenance of protein location in cell GO:0032507 89 37 2,000 9,316E-04 0,01197793 ! negative regulation of cell activation GO:0050866 69 37 2,000 9,316E-04 0,01191522 ! regulation of activated T cell proliferation GO:0046006 19 9 1,000 9,368E-04 0,01192038 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 9,368E-04 0,01185862 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 1,000 9,368E-04 0,01179749 ! receptor clustering GO:0043113 20 9 1,000 9,368E-04 0,01173699 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 9,368E-04 0,01167711 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 9,368E-04 0,01161783 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 1,000 9,368E-04 0,01155916 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,167E-03 0,0143274 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,167E-03 0,01425576 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,167E-03 0,01418484 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,167E-03 0,01411462 ! lung alveolus development GO:0048286 26 10 1,000 1,167E-03 0,01404509 ! intestinal cholesterol absorption GO:0030299 19 10 1,000 1,167E-03 0,01397624 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,167E-03 0,01390806 GO:0045685|regulation of glial cell differentiation, ! midbrain development GO:0030901 14 10 1,000 1,167E-03 0,01384055 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,167E-03 0,01377368 ! nucleus organization GO:0006997 73 40 2,000 1,171E-03 0,0137551 ! regulation of DNA binding GO:0051101 167 89 3,000 1,204E-03 0,01407859 ! positive regulation of protein modification process GO:0031401 156 90 3,000 1,255E-03 0,01460461 ! maintenance of protein location GO:0045185 95 41 2,000 1,259E-03 0,01457463 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,422E-03 0,01638153 ! cardiac cell differentiation GO:0035051 36 11 1,000 1,422E-03 0,01630462 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 2,000 1,446E-03 0,01651071 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,446E-03 0,01643392 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,546E-03 0,01748834 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,65E-03 0,01858061 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,65E-03 0,01849538 ! maintenance of location in cell GO:0051651 101 45 2,000 1,65E-03 0,01841093 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 1,655E-03 0,01838116 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,7E-03 0,01879315 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,7E-03 0,0187085 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,7E-03 0,0186246 ! mitotic spindle organization GO:0007052 23 12 1,000 1,7E-03 0,01854146 ! lipid digestion GO:0044241 21 12 1,000 1,7E-03 0,01845905 ! T cell homeostasis GO:0043029 28 12 1,000 1,7E-03 0,01837738 ! localization within membrane GO:0051668 26 12 1,000 1,7E-03 0,01829642 ! leukocyte migration GO:0050900 75 46 2,000 1,759E-03 0,01884643 ! hormone metabolic process GO:0042445 171 100 3,000 1,851E-03 0,0197463 ! positive regulation of defense response GO:0031349 88 48 2,000 1,989E-03 0,02112616 ! regulation of inflammatory response GO:0050727 84 48 2,000 1,989E-03 0,0210347 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,002E-03 0,02108509 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,002E-03 0,0209946 ! regulation of ossification GO:0030278 123 50 2,000 2,237E-03 0,02335367 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 2,328E-03 0,02420271 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,368E-03 0,02451007 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 2,503E-03 0,02580314 ! vesicle organization GO:0016050 127 53 2,000 2,643E-03 0,0271336 ! synapse organization GO:0050808 102 53 2,000 2,643E-03 0,02702007 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 2,677E-03 0,02725152 ! intestinal absorption GO:0050892 31 15 1,000 2,677E-03 0,02713844 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,677E-03 0,0270263 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 2,677E-03 0,02691508 ! activation of phospholipase C activity GO:0007202 110 54 2,000 2,788E-03 0,02791747 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 2,000 2,788E-03 0,02780352 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,788E-03 0,0276905 ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 2,938E-03 0,0290594 ! isoprenoid biosynthetic process GO:0008299 34 16 1,000 3,049E-03 0,03003759 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 3,049E-03 0,02991695 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,049E-03 0,02979728 ! regulation of bone remodeling GO:0046850 143 57 2,000 3,252E-03 0,03165344 ! regulation of phospholipase activity GO:0010517 113 57 2,000 3,252E-03 0,03152784 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,417E-03 0,03299127 ! regulation of tissue remodeling GO:0034103 146 58 2,000 3,417E-03 0,03286138 ! positive regulation of lipase activity GO:0060193 115 58 2,000 3,417E-03 0,03273252 ! maintenance of location GO:0051235 124 58 2,000 3,417E-03 0,03260465 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,444E-03 0,03273894 ! signal complex assembly GO:0007172 47 17 1,000 3,444E-03 0,03261205 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 3,444E-03 0,03248613 ! DNA catabolic process GO:0006308 94 60 2,000 3,761E-03 0,03533515 ! kidney development GO:0001822 133 60 2,000 3,761E-03 0,03519977 ! cell-substrate junction assembly GO:0007044 56 18 1,000 3,861E-03 0,03600584 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 3,861E-03 0,03586894 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 3,861E-03 0,03573307 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 3,861E-03 0,03559823 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 3,861E-03 0,0354644 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 3,94E-03 0,03605219 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,301E-03 0,03920747 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 4,301E-03 0,03906171 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,301E-03 0,03891704 ! memory GO:0007613 34 19 1,000 4,301E-03 0,03877344 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,301E-03 0,03863089 ! pigmentation during development GO:0048066 42 19 1,000 4,301E-03 0,03848938 ! proximal/distal pattern formation GO:0009954 33 19 1,000 4,301E-03 0,03834891 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 4,51E-03 0,04006584 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 4,51E-03 0,03992068 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,711E-03 0,04154429 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 4,763E-03 0,04185444 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,763E-03 0,04170442 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 4,763E-03 0,04155548 ! cellular response to unfolded protein GO:0034620 35 20 1,000 4,763E-03 0,04140759 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 4,763E-03 0,04126076 ! negative regulation of translation GO:0017148 32 20 1,000 4,763E-03 0,04111496 ! lipid phosphorylation GO:0046834 43 21 1,000 5,246E-03 0,04512939 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 5,246E-03 0,04497105 ! plasma membrane fusion GO:0045026 33 21 1,000 5,246E-03 0,0448138 ! regulation of vasoconstriction GO:0019229 40 21 1,000 5,246E-03 0,04465766 ! regulation of lipase activity GO:0060191 137 68 2,000 5,344E-03 0,04532963 ! homeostasis of number of cells GO:0048872 131 69 2,000 5,566E-03 0,04704854 ! glutamate signaling pathway GO:0007215 48 22 1,000 5,751E-03 0,04845058 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 5,751E-03 0,04828408 ! cholesterol biosynthetic process GO:0006695 39 22 1,000 5,751E-03 0,04811873 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 5,751E-03 0,0479545 ! positive regulation of B cell activation GO:0050871 42 22 1,000 5,751E-03 0,04779139 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,751E-03 0,04762938 ! protein stabilization GO:0050821 41 22 1,000 5,751E-03 0,04746847 ! protein amino acid O-linked glycosylation GO:0006493 45 24 1,000 6,825E-03 0,05614259 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 6,825E-03 0,05595419 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 6,825E-03 0,05576705 ! platelet activation GO:0030168 41 24 1,000 6,825E-03 0,05558116 ! negative regulation of catabolic process GO:0009895 52 24 1,000 6,825E-03 0,0553965 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 7,013E-03 0,05673008 ! learning or memory GO:0007611 161 76 2,000 7,274E-03 0,05864561 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 7,394E-03 0,05941769 ! leukocyte adhesion GO:0007159 55 25 1,000 7,394E-03 0,05922288 ! phototransduction GO:0007602 37 25 1,000 7,394E-03 0,05902934 ! receptor metabolic process GO:0043112 53 25 1,000 7,394E-03 0,05883706 ! leukocyte homeostasis GO:0001776 50 25 1,000 7,394E-03 0,05864603 ! myelination GO:0042552 50 26 1,000 7,983E-03 0,06311344 ! macromolecular complex disassembly GO:0032984 54 26 1,000 7,983E-03 0,06290985 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 7,983E-03 0,06270757 ! digestive system process GO:0022600 49 26 1,000 7,983E-03 0,06250658 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 7,983E-03 0,06230688 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 7,983E-03 0,06210845 ! positive regulation of nuclear division GO:0051785 41 26 1,000 7,983E-03 0,06191128 GO:0045840|positive regulation of mitosis, ! steroid biosynthetic process GO:0006694 146 79 2,000 8,09E-03 0,06254613 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 8,592E-03 0,06621775 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 8,592E-03 0,06600951 ! regulation of chromosome organization GO:0033044 49 27 1,000 8,592E-03 0,06580259 ! meiosis GO:0007126 143 81 2,000 8,663E-03 0,06614013 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 8,663E-03 0,06593408 ! meiotic cell cycle GO:0051321 144 82 2,000 8,959E-03 0,06796971 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 9,222E-03 0,06975028 ! fat cell differentiation GO:0045444 57 28 1,000 9,222E-03 0,06953501 ! base-excision repair GO:0006284 41 28 1,000 9,222E-03 0,06932105 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 9,222E-03 0,06910841 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,222E-03 0,06889707 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 9,872E-03 0,07352578 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 9,872E-03 0,0733023 ! synaptogenesis GO:0007416 46 29 1,000 9,872E-03 0,07308017 ! mitochondrion organization GO:0007005 159 87 2,000 0,01052324 0,07766852 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 1,000 0,01054107 0,07756576 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sterol biosynthetic process GO:0016126 56 30 1,000 0,01054107 0,07733283 ! tube morphogenesis GO:0035239 194 89 2,000 0,0111905 0,08185146 ! zinc ion transport GO:0006829 54 31 1,000 0,01123002 0,08189531 ! detection of light stimulus GO:0009583 44 31 1,000 0,01123002 0,08165157 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01123002 0,08140928 GO:0008366|axon ensheathment, ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01123002 0,08116843 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01153309 0,08311308 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01193828 0,08578005 ! mesoderm formation GO:0001707 73 32 1,000 0,01193828 0,08552849 ! hindbrain development GO:0030902 65 32 1,000 0,01193828 0,08527841 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,01266564 0,09021039 GO:0055092|sterol homeostasis, ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,01266564 0,08994815 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01266564 0,08968743 ! regulation of defense response GO:0031347 171 95 2,000 0,01333631 0,0941636 ! glial cell differentiation GO:0010001 67 34 1,000 0,01341189 0,09442436 ! cholesterol transport GO:0030301 62 34 1,000 0,01341189 0,09415302 ! spliceosome assembly GO:0000245 75 34 1,000 0,01341189 0,09388324 ! formation of primary germ layer GO:0001704 76 34 1,000 0,01341189 0,093615 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01371511 0,09545876 ! transcription initiation GO:0006352 171 97 2,000 0,0141 0,09785882 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01417681 0,09811319 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,01417681 0,09783603 ! sterol transport GO:0015918 63 35 1,000 0,01417681 0,09756044 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01417681 0,09728639 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,0149602 0,10237469 ! positive regulation of cell development GO:0010720 85 36 1,000 0,0149602 0,10208872 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01576183 0,1072595 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01576183 0,10696156 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01576183 0,10666526 ! odontogenesis GO:0042476 74 37 1,000 0,01576183 0,10637061 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01658151 0,11159405 ! meiosis I GO:0007127 74 38 1,000 0,01658151 0,11128747 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01658151 0,11098258 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01741903 0,11626967 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01741903 0,11595286 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01741903 0,11563777 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 0,01827419 0,12098601 ! lipid homeostasis GO:0055088 75 40 1,000 0,01827419 0,12065902 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01827419 0,1203338 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,01914677 0,12574076 ! gliogenesis GO:0042063 91 41 1,000 0,01914677 0,12540365 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01914677 0,12506835 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,02003658 0,13053167 ! cytokinesis GO:0000910 84 42 1,000 0,02003658 0,13018451 ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02094343 0,13571564 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,02094343 0,1353566 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02094343 0,13499946 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02094343 0,1346442 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,0218671 0,14021347 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,02280741 0,14585998 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02376416 0,15158187 ! pigmentation GO:0043473 103 46 1,000 0,02376416 0,15118712 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,02376416 0,15079443 ! response to insulin stimulus GO:0032868 98 47 1,000 0,02473716 0,15656189 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02561824 0,16171929 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02561824 0,16130249 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02561824 0,16088783 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02561824 0,1604753 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02561824 0,16006487 ! neuron fate determination GO:0048664 7 5 0,000 0,02561824 0,15965654 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02561824 0,15925029 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02561824 0,1588461 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02561824 0,15844396 ! polyol transport GO:0015791 12 5 0,000 0,02561824 0,15804385 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02561824 0,15764576 ! response to superoxide GO:0000303 10 5 0,000 0,02561824 0,15724966 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02561824 0,15685555 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02561824 0,15646341 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02561824 0,15607323 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02561824 0,15568499 ! female meiosis GO:0007143 10 5 0,000 0,02561824 0,15529867 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02561824 0,15491427 ! hypothalamus development GO:0021854 9 5 0,000 0,02561824 0,15453177 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02561824 0,15415115 ! cobalt ion transport GO:0006824 11 5 0,000 0,02561824 0,1537724 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02561824 0,1533955 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02561824 0,15302045 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02561824 0,15264723 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02561824 0,15227583 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02561824 0,15190623 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02561824 0,15153841 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02561824 0,15117238 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02561824 0,15080811 ! transposition GO:0032196 9 5 0,000 0,02561824 0,15044559 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02561824 0,15008481 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02561824 0,14972575 ! negative chemotaxis GO:0050919 16 5 0,000 0,02561824 0,14936841 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02561824 0,14901277 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02561824 0,14865882 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02561824 0,14830655 ! behavioral response to pain GO:0048266 10 5 0,000 0,02561824 0,14795595 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02561824 0,14760699 ! Notch receptor processing GO:0007220 11 5 0,000 0,02561824 0,14725968 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02561824 0,146914 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02561824 0,14656994 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02561824 0,14622749 ! copulation GO:0007620 9 5 0,000 0,02561824 0,14588663 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02561824 0,14554736 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02561824 0,14520966 ! bioluminescence GO:0008218 9 5 0,000 0,02561824 0,14487353 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02561824 0,14453895 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02561824 0,14420591 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02561824 0,1438744 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02561824 0,14354442 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02561824 0,14321594 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02561824 0,14288896 ! grooming behavior GO:0007625 6 5 0,000 0,02561824 0,14256347 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02561824 0,14223947 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02561824 0,14191693 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02561824 0,14159585 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02561824 0,14127622 ! response to protozoan GO:0001562 13 5 0,000 0,02561824 0,14095803 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02561824 0,14064127 ! lymph vessel development GO:0001945 10 5 0,000 0,02561824 0,14032593 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02561824 0,140012 ! endochondral ossification GO:0001958 17 5 0,000 0,02561824 0,13969948 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02561824 0,13938834 ! single strand break repair GO:0000012 8 5 0,000 0,02561824 0,13907859 ! parathyroid gland development GO:0060017 14 5 0,000 0,02561824 0,13877021 ! anagen GO:0042640 7 5 0,000 0,02561824 0,1384632 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02561824 0,13815754 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02561824 0,13785323 ! cytokine secretion GO:0050663 15 5 0,000 0,02561824 0,13755025 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02561824 0,13724861 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02561824 0,13694828 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02561824 0,13664927 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02561824 0,13635156 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02561824 0,13605514 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02561824 0,13576001 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02561824 0,13546616 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02561824 0,13517357 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02561824 0,13488225 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02561824 0,13459218 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02561824 0,13430336 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02561824 0,13401577 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02561824 0,13372941 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02561824 0,13344428 ! microvillus organization GO:0032528 8 5 0,000 0,02561824 0,13316035 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02561824 0,13287763 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02561824 0,13259611 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02561824 0,13231578 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02561824 0,13203664 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02561824 0,13175866 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02561824 0,13148186 ! polyol catabolic process GO:0046174 9 5 0,000 0,02561824 0,13120622 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02561824 0,13093173 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02561824 0,13065838 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02561824 0,13038618 ! muscle cell migration GO:0014812 8 5 0,000 0,02561824 0,1301151 ! mitochondrial fission GO:0000266 8 5 0,000 0,02561824 0,12984516 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02561824 0,12957633 ! mRNA transcription GO:0009299 10 5 0,000 0,02561824 0,12930861 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02561824 0,12904199 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02561824 0,12877647 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02561824 0,12851204 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02561824 0,1282487 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02561824 0,12798643 ! monocyte activation GO:0042117 10 5 0,000 0,02561824 0,12772523 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02561824 0,1274651 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02561824 0,12720603 ! response to food GO:0032094 6 5 0,000 0,02561824 0,126948 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02561824 0,12669102 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02561824 0,12643508 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02561824 0,12618017 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02561824 0,12592629 ! forebrain neuron development GO:0021884 13 5 0,000 0,02561824 0,12567342 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02561824 0,12542157 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02561824 0,12517073 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02561824 0,12492089 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02561824 0,12467204 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02561824 0,12442419 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02561824 0,12417731 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02561824 0,12393142 ! lipid glycosylation GO:0030259 7 5 0,000 0,02561824 0,12368649 ! nucleobase transport GO:0015851 6 5 0,000 0,02561824 0,12344253 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02561824 0,12319954 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02561824 0,1229575 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02561824 0,1227164 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02561824 0,12247625 ! basic amino acid transport GO:0015802 12 5 0,000 0,02561824 0,12223704 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02561824 0,12199876 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02561824 0,12176141 ! actin nucleation GO:0045010 11 5 0,000 0,02561824 0,12152498 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02561824 0,12128947 ! depurination GO:0045007 5 5 0,000 0,02561824 0,12105486 ! depyrimidination GO:0045008 10 5 0,000 0,02561824 0,12082117 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02561824 0,12058837 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02561824 0,12035647 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02561824 0,12012546 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02561824 0,11989534 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02561824 0,11966609 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02561824 0,11943772 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02561824 0,11921022 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02561824 0,11898358 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02561824 0,11875781 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02561824 0,11853289 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02561824 0,11830882 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02561824 0,11808559 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02561824 0,11786321 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02561824 0,11764166 ! response to arsenic GO:0046685 11 5 0,000 0,02561824 0,11742095 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02561824 0,11720106 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02561824 0,11698199 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02561824 0,11676374 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02561824 0,1165463 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02561824 0,11632967 ! response to mercury ion GO:0046689 8 5 0,000 0,02561824 0,11611385 ! response to cadmium ion GO:0046686 7 5 0,000 0,02561824 0,11589882 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02561824 0,11568459 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02561824 0,11547115 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02561824 0,1152585 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02561824 0,11504663 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02561824 0,11483553 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02561824 0,11462521 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02561824 0,11441566 ! decidualization GO:0046697 11 5 0,000 0,02561824 0,11420687 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02561824 0,11399884 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02561824 0,11379157 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02561824 0,11358505 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02561824 0,11337928 ! embryonic cleavage GO:0040016 6 5 0,000 0,02561824 0,11317426 ! peroxisome fission GO:0016559 5 5 0,000 0,02561824 0,11296997 ! histone demethylation GO:0016577 13 5 0,000 0,02561824 0,11276642 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02561824 0,11256361 ! mitotic recombination GO:0006312 9 5 0,000 0,02561824 0,11236152 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02561824 0,11216015 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02561824 0,11195951 ! metaphase plate congression GO:0051310 7 5 0,000 0,02561824 0,11175958 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02561824 0,11156037 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02561824 0,11136186 ! enteric nervous system development GO:0048484 8 5 0,000 0,02561824 0,11116406 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02561824 0,11096696 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02561824 0,11077056 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02561824 0,11057485 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02561824 0,11037983 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02561824 0,1101855 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02561824 0,10999185 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02561824 0,10979889 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02561824 0,10960659 ! metaphase GO:0051323 11 5 0,000 0,02561824 0,10941497 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02561824 0,10922402 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02561824 0,10903374 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02561824 0,10884411 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02561824 0,10865515 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02561824 0,10846684 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02561824 0,10827918 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02561824 0,10809217 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02561824 0,1079058 ! response to redox state GO:0051775 6 5 0,000 0,02561824 0,10772008 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02561824 0,10753499 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02561824 0,10735054 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02561824 0,10716672 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02561824 0,10698353 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02561824 0,10680096 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02561824 0,10661902 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02561824 0,1064377 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02561824 0,10625699 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02561824 0,10607689 ! striatum development GO:0021756 14 5 0,000 0,02561824 0,1058974 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02561824 0,10571852 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02561824 0,10554024 ! glial cell migration GO:0008347 10 5 0,000 0,02561824 0,10536257 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02561824 0,10518549 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02561824 0,105009 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02561824 0,10483311 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02561824 0,1046578 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02561824 0,10448308 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02561824 0,10430894 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02561824 0,10413538 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02561824 0,1039624 ! neuroprotection GO:0043526 8 5 0,000 0,02561824 0,10378999 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02561824 0,10361815 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02561824 0,10344688 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02561824 0,10327618 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02561824 0,10310604 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02561824 0,10293646 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02561824 0,10276743 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02561824 0,10259896 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02561824 0,10243104 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02561824 0,10226367 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02561824 0,10209684 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02561824 0,10193056 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02561824 0,10176482 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02561824 0,10159962 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02561824 0,10143495 ! protein palmitoylation GO:0018345 12 5 0,000 0,02561824 0,10127082 ! drug metabolic process GO:0017144 7 5 0,000 0,02561824 0,10110721 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02561824 0,10094414 ! organ regeneration GO:0031100 7 5 0,000 0,02561824 0,10078159 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02561824 0,10061956 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02561824 0,10045805 ! endosome transport GO:0016197 127 48 1,000 0,02572621 0,10071978 ! response to calcium ion GO:0051592 94 49 1,000 0,02673113 0,10448665 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02673113 0,10431974 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02673113 0,10415336 ! regulation of action potential GO:0001508 102 50 1,000 0,02775172 0,10795775 ! activation of caspase activity GO:0006919 95 50 1,000 0,02775172 0,10778611 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02775172 0,10761502 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02878781 0,1114558 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,02983919 0,11534358 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03066302 0,11834084 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03066302 0,11815418 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03066302 0,11796811 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03066302 0,11778262 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03066302 0,11759772 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03066302 0,1174134 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03066302 0,11722965 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03066302 0,11704648 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03066302 0,11686388 ! response to oxygen radical GO:0000305 11 6 0,000 0,03066302 0,11668185 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03066302 0,11650039 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03066302 0,11631949 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03066302 0,11613915 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03066302 0,11595936 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03066302 0,11578014 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03066302 0,11560147 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03066302 0,11542334 ! forebrain regionalization GO:0021871 9 6 0,000 0,03066302 0,11524577 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03066302 0,11506874 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03066302 0,11489225 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03066302 0,11471631 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03066302 0,1145409 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03066302 0,11436603 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03066302 0,11419169 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03066302 0,11401788 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03066302 0,1138446 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03066302 0,11367185 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03066302 0,11349962 ! malate metabolic process GO:0006108 13 6 0,000 0,03066302 0,11332791 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03066302 0,11315672 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03066302 0,11298605 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03066302 0,11281589 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03066302 0,11264624 ! protein refolding GO:0042026 15 6 0,000 0,03066302 0,1124771 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03066302 0,11230847 ! opsonization GO:0008228 8 6 0,000 0,03066302 0,11214034 ! mating behavior GO:0007617 7 6 0,000 0,03066302 0,11197272 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03066302 0,1118056 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03066302 0,11163897 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03066302 0,11147284 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03066302 0,11130721 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03066302 0,11114206 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03066302 0,11097741 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03066302 0,11081324 ! toxin metabolic process GO:0009404 11 6 0,000 0,03066302 0,11064956 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03066302 0,11048636 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03066302 0,11032364 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03066302 0,1101614 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03066302 0,10999963 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03066302 0,10983834 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03066302 0,10967752 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03066302 0,10951718 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03066302 0,1093573 ! thymic T cell selection GO:0045061 16 6 0,000 0,03066302 0,10919789 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03066302 0,10903894 ! protein lipoylation GO:0009249 10 6 0,000 0,03066302 0,10888045 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03066302 0,10872242 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03066302 0,10856485 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03066302 0,10840774 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03066302 0,10825108 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03066302 0,10809488 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03066302 0,10793912 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03066302 0,10778381 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03066302 0,10762895 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03066302 0,10747453 ! hyperosmotic response GO:0006972 10 6 0,000 0,03066302 0,10732056 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03066302 0,10716702 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03066302 0,10701393 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03066302 0,10686127 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03066302 0,10670904 ! urea metabolic process GO:0019627 7 6 0,000 0,03066302 0,10655725 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03066302 0,10640589 ! neutrophil activation GO:0042119 7 6 0,000 0,03066302 0,10625496 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03066302 0,10610446 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03066302 0,10595438 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03066302 0,10580473 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03066302 0,1056555 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03066302 0,10550669 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03066302 0,1053583 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03066302 0,10521032 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03066302 0,10506276 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03066302 0,10491562 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03066302 0,10476888 ! carnitine transport GO:0015879 10 6 0,000 0,03066302 0,10462256 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03066302 0,10447664 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03066302 0,10433113 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03066302 0,10418602 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03066302 0,10404132 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03066302 0,10389702 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03066302 0,10375312 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03066302 0,10360961 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03066302 0,1034665 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03066302 0,10332379 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03066302 0,10318147 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03066302 0,10303955 ! response to UV-C GO:0010225 14 6 0,000 0,03066302 0,10289801 ! astrocyte development GO:0014002 16 6 0,000 0,03066302 0,10275686 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03066302 0,1026161 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03066302 0,10247572 ! interaction with symbiont GO:0051702 14 6 0,000 0,03066302 0,10233572 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03066302 0,10219611 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03066302 0,10205688 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03066302 0,10191803 ! response to copper ion GO:0046688 10 6 0,000 0,03066302 0,10177955 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03066302 0,10164145 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03066302 0,10150373 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03066302 0,10136637 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03066302 0,10122939 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03066302 0,10109278 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03066302 0,10095654 ! hair follicle maturation GO:0048820 8 6 0,000 0,03066302 0,10082066 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03066302 0,10068515 ! Schwann cell development GO:0014044 15 6 0,000 0,03066302 0,10055 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03066302 0,10041521 ! response to pheromone GO:0019236 6 6 0,000 0,03066302 0,10028079 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03066302 0,10014672 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03066302 0,10001302 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03066302 0,09987967 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03066302 0,09974667 ! subpallium development GO:0021544 15 6 0,000 0,03066302 0,09961403 ! neural tube patterning GO:0021532 8 6 0,000 0,03066302 0,09948174 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03066302 0,0993498 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03066302 0,09921821 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03066302 0,09908697 ! G2 phase GO:0051319 16 6 0,000 0,03066302 0,09895608 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03066302 0,09882553 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03066302 0,09869532 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03066302 0,09856546 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03066302 0,09843594 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03066302 0,09830676 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03066302 0,09817792 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03066302 0,09804941 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03066302 0,09792124 ! receptor internalization GO:0031623 11 6 0,000 0,03066302 0,09779341 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03066302 0,09766591 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03066302 0,09753874 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03066302 0,0974119 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03066302 0,09728539 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03066302 0,09715921 ! protein deubiquitination GO:0016579 16 6 0,000 0,03066302 0,09703335 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03066302 0,09690783 ! protein destabilization GO:0031648 9 6 0,000 0,03066302 0,09678262 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03066302 0,09665774 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03066302 0,09653318 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03066302 0,09640894 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03066302 0,09628502 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03066302 0,09616142 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03066302 0,09603814 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03066302 0,09591517 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03066302 0,09579252 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03066302 0,09567018 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03066302 0,09554815 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03066302 0,09542643 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03066302 0,09530502 ! neural plate development GO:0001840 9 6 0,000 0,03066302 0,09518393 ! catecholamine transport GO:0051937 9 6 0,000 0,03066302 0,09506313 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03066302 0,09494265 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03066302 0,09482247 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03066302 0,09470259 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03066302 0,09458302 ! maternal placenta development GO:0001893 12 6 0,000 0,03066302 0,09446374 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03066302 0,09434477 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03066302 0,0942261 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03066302 0,09410773 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03066302 0,09398965 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03066302 0,09387187 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03066302 0,09375438 GO:0055081|anion homeostasis, ! regulation of translational initiation GO:0006446 87 54 1,000 0,03198713 0,0976807 ! membrane fusion GO:0006944 122 54 1,000 0,03198713 0,09755875 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03419409 0,10415979 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,03531925 0,1074532 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 1,000 0,03531925 0,10731955 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03531925 0,10718624 ! tRNA transcription GO:0009304 17 7 0,000 0,03568181 0,1081522 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03568181 0,10801818 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03568181 0,10788449 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03568181 0,10775114 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03568181 0,10761811 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03568181 0,10748541 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03568181 0,10735304 ! sleep GO:0030431 16 7 0,000 0,03568181 0,107221 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03568181 0,10708928 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03568181 0,10695788 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03568181 0,1068268 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03568181 0,10669605 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03568181 0,10656561 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03568181 0,10643549 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03568181 0,1063057 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03568181 0,10617621 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03568181 0,10604704 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03568181 0,10591819 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03568181 0,10578965 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03568181 0,10566142 ! glycolipid transport GO:0046836 11 7 0,000 0,03568181 0,1055335 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03568181 0,10540589 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03568181 0,10527859 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03568181 0,10515159 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03568181 0,1050249 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03568181 0,10489852 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03568181 0,10477244 ! mRNA stabilization GO:0048255 18 7 0,000 0,03568181 0,10464666 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03568181 0,10452119 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03568181 0,10439601 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03568181 0,10427114 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03568181 0,10414656 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03568181 0,10402228 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03568181 0,1038983 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03568181 0,10377461 ! lipoprotein transport GO:0042953 14 7 0,000 0,03568181 0,10365121 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03568181 0,10352811 ! rhythmic behavior GO:0007622 17 7 0,000 0,03568181 0,1034053 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03568181 0,10328278 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03568181 0,10316056 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03568181 0,10303862 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03568181 0,10291697 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03568181 0,1027956 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03568181 0,10267452 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03568181 0,10255373 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03568181 0,10243322 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03568181 0,10231299 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03568181 0,10219305 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03568181 0,10207338 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03568181 0,101954 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03568181 0,1018349 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03568181 0,10171607 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03568181 0,10159752 ! spinal cord patterning GO:0021511 14 7 0,000 0,03568181 0,10147924 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03568181 0,10136124 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03568181 0,10124352 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03568181 0,10112607 ! adrenal gland development GO:0030325 17 7 0,000 0,03568181 0,10100889 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03568181 0,10089198 ! ovulation GO:0030728 10 7 0,000 0,03568181 0,10077534 ! adenohypophysis development GO:0021984 11 7 0,000 0,03568181 0,10065897 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03568181 0,10054287 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03568181 0,10042704 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03568181 0,10031147 ! microtubule nucleation GO:0007020 21 7 0,000 0,03568181 0,10019617 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03568181 0,10008114 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03568181 0,09996637 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03568181 0,09985186 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03568181 0,09973761 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03568181 0,09962362 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03568181 0,0995099 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03568181 0,09939643 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03568181 0,09928322 ! galactose metabolic process GO:0006012 13 7 0,000 0,03568181 0,09917027 ! vesicle fusion GO:0006906 20 7 0,000 0,03568181 0,09905758 ! response to dietary excess GO:0002021 8 7 0,000 0,03568181 0,09894514 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03568181 0,09883296 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03568181 0,09872103 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03568181 0,09860936 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03568181 0,09849793 ! nucleoside transport GO:0015858 11 7 0,000 0,03568181 0,09838676 ! nucleoside salvage GO:0043174 11 7 0,000 0,03568181 0,09827584 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03568181 0,09816517 ! male sex determination GO:0030238 15 7 0,000 0,03568181 0,09805475 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03568181 0,09794457 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03568181 0,09783465 ! parturition GO:0007567 16 7 0,000 0,03568181 0,09772497 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03568181 0,09761553 ! rRNA modification GO:0000154 14 7 0,000 0,03568181 0,09750634 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03568181 0,0973974 ! spindle checkpoint GO:0031577 16 7 0,000 0,03568181 0,09728869 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03568181 0,09718023 ! monocyte differentiation GO:0030224 16 7 0,000 0,03568181 0,09707202 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03568181 0,09696404 ! centrosome duplication GO:0051298 14 7 0,000 0,03568181 0,0968563 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03568181 0,0967488 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03568181 0,09664154 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03568181 0,09653452 ! fibrinolysis GO:0042730 11 7 0,000 0,03568181 0,09642773 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03568181 0,09632118 ! eating behavior GO:0042755 8 7 0,000 0,03568181 0,09621487 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03568181 0,09610879 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03568181 0,09600294 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03568181 0,09589733 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03568181 0,09579195 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03568181 0,0956868 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03568181 0,09558188 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03568181 0,09547719 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03568181 0,09537272 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03568181 0,09526849 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03568181 0,09516449 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03568181 0,09506071 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03568181 0,09495716 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03568181 0,09485383 ! histone ubiquitination GO:0016574 9 7 0,000 0,03568181 0,09475073 ! regulation of meiosis GO:0040020 12 7 0,000 0,03568181 0,09464785 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03568181 0,0945452 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03568181 0,09444276 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03568181 0,09434055 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03568181 0,09423856 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03568181 0,09413679 ! transcription termination GO:0006353 14 7 0,000 0,03568181 0,09403524 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03568181 0,09393391 ! anaphase GO:0051322 18 7 0,000 0,03568181 0,0938328 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03568181 0,0937319 ! axonal fasciculation GO:0007413 19 7 0,000 0,03568181 0,09363122 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03568181 0,09353076 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03568181 0,09343051 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03568181 0,09333048 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03568181 0,09323066 ! diuresis GO:0030146 12 7 0,000 0,03568181 0,09313106 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03568181 0,09303167 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03568181 0,09293248 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03568181 0,09283351 ! antibiotic transport GO:0042891 9 7 0,000 0,03568181 0,09273476 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03568181 0,09263621 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03568181 0,09253787 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03568181 0,09243974 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03568181 0,09234181 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03568181 0,0922441 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03568181 0,09214659 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03568181 0,09204928 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03568181 0,09195218 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03568181 0,09185529 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03568181 0,0917586 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03568181 0,09166211 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03568181 0,09156583 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03568181 0,09146975 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03568181 0,09137387 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03568181 0,09127819 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03568181 0,09118271 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03568181 0,09108743 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03568181 0,09099235 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03568181 0,09089747 ! muscle adaptation GO:0043500 13 7 0,000 0,03568181 0,09080278 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03568181 0,09070829 ! retina homeostasis GO:0001895 12 7 0,000 0,03568181 0,090614 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03568181 0,09051991 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03568181 0,09042601 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03568181 0,0903323 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03568181 0,09023879 ! aging GO:0007568 112 58 1,000 0,03645863 0,09210799 ! gastrulation GO:0007369 122 58 1,000 0,03645863 0,09201284 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03645863 0,09191788 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03761205 0,09472808 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,03996033 0,10053871 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04067477 0,10223092 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04067477 0,10212585 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04067477 0,102021 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04067477 0,10191636 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04067477 0,10181194 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04067477 0,10170773 ! male meiosis GO:0007140 9 8 0,000 0,04067477 0,10160373 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04067477 0,10149995 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04067477 0,10139638 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04067477 0,10129302 ! meiotic prophase I GO:0007128 14 8 0,000 0,04067477 0,10118987 ! response to zinc ion GO:0010043 12 8 0,000 0,04067477 0,10108693 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04067477 0,1009842 ! oligopeptide transport GO:0006857 16 8 0,000 0,04067477 0,10088168 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04067477 0,10077936 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04067477 0,10067726 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04067477 0,10057536 ! signal peptide processing GO:0006465 12 8 0,000 0,04067477 0,10047366 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04067477 0,10037217 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04067477 0,10027089 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04067477 0,10016981 ! succinate metabolic process GO:0006105 17 8 0,000 0,04067477 0,10006894 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04067477 0,09996826 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04067477 0,09986779 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04067477 0,09976752 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04067477 0,09966746 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04067477 0,09956759 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04067477 0,09946792 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04067477 0,09936845 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04067477 0,09926918 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04067477 0,09917011 ! reflex GO:0060004 17 8 0,000 0,04067477 0,09907124 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04067477 0,09897256 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04067477 0,09887408 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04067477 0,0987758 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04067477 0,09867771 ! pigment granule organization GO:0048753 17 8 0,000 0,04067477 0,09857981 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04067477 0,09848211 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04067477 0,09838461 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04067477 0,09828729 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04067477 0,09819017 ! histidine catabolic process GO:0006548 10 8 0,000 0,04067477 0,09809324 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04067477 0,0979965 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04067477 0,09789995 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04067477 0,0978036 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04067477 0,09770743 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04067477 0,09761145 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04067477 0,09751566 ! melanin metabolic process GO:0006582 17 8 0,000 0,04067477 0,09742005 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04067477 0,09732464 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04067477 0,09722941 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04067477 0,09713436 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04067477 0,0970395 ! macrophage activation GO:0042116 13 8 0,000 0,04067477 0,09694483 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04067477 0,09685034 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04067477 0,09675604 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04067477 0,09666192 ! purine salvage GO:0043101 12 8 0,000 0,04067477 0,09656798 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04067477 0,09647423 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04067477 0,09638065 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04067477 0,09628726 ! osteoblast development GO:0002076 17 8 0,000 0,04067477 0,09619405 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04067477 0,09610102 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04067477 0,09600817 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04067477 0,09591549 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04067477 0,095823 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04067477 0,09573069 ! response to UV-B GO:0010224 17 8 0,000 0,04067477 0,09563855 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04067477 0,09554659 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04067477 0,09545481 ! intermediate filament organization GO:0045109 12 8 0,000 0,04067477 0,0953632 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04067477 0,09527177 ! cellular extravasation GO:0045123 13 8 0,000 0,04067477 0,09518051 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04067477 0,09508943 ! response to antibiotic GO:0046677 11 8 0,000 0,04067477 0,09499852 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04067477 0,09490779 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04067477 0,09481723 ! DNA topological change GO:0006265 12 8 0,000 0,04067477 0,09472684 ! response to tropane GO:0014073 15 8 0,000 0,04067477 0,09463662 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04067477 0,09454658 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04067477 0,0944567 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04067477 0,094367 ! mast cell activation GO:0045576 14 8 0,000 0,04067477 0,09427747 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04067477 0,09418811 ! gas homeostasis GO:0033483 14 8 0,000 0,04067477 0,09409891 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04067477 0,09400989 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04067477 0,09392103 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04067477 0,09383234 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04067477 0,09374382 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04067477 0,09365547 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04067477 0,09356728 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04067477 0,09347926 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04067477 0,0933914 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04067477 0,09330371 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04067477 0,09321618 ! response to tumor cell GO:0002347 16 8 0,000 0,04067477 0,09312882 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04067477 0,09304162 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04067477 0,09295459 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04067477 0,09286771 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04067477 0,092781 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04067477 0,09269445 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04067477 0,09260806 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04067477 0,09252184 ! hormone catabolic process GO:0042447 17 8 0,000 0,04067477 0,09243577 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04067477 0,09234986 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04067477 0,09226412 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04067477 0,09217853 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04067477 0,0920931 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04067477 0,09200783 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04067477 0,09192271 ! adult feeding behavior GO:0008343 10 8 0,000 0,04067477 0,09183776 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04067477 0,09175296 ! ATP catabolic process GO:0006200 11 8 0,000 0,04067477 0,09166831 ! blastocyst growth GO:0001832 19 8 0,000 0,04067477 0,09158383 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04067477 0,0914995 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04067477 0,09141532 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04067477 0,0913313 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04067477 0,09124743 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04067477 0,09116372 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04067477 0,09108016 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04067477 0,09099675 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04067477 0,0909135 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04067477 0,0908304 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04067477 0,09074745 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04067477 0,09066465 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04067477 0,090582 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04067477 0,0904995 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04067477 0,09041715 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04067477 0,09033496 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04067477 0,09025291 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04067477 0,09017101 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04067477 0,09008926 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04067477 0,09000766 ! regulation of mitosis GO:0007088 112 63 1,000 0,04236271 0,093658 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,04236271 0,09357332 ! axon extension GO:0048675 16 9 0,000 0,04564201 0,10072576 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04564201 0,10063486 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04564201 0,10054411 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04564201 0,10045353 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04564201 0,10036311 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04564201 0,10027286 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04564201 0,10018277 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04564201 0,10009284 ! reproductive behavior GO:0019098 22 9 0,000 0,04564201 0,10000307 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04564201 0,09991346 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04564201 0,09982401 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04564201 0,09973472 ! UTP metabolic process GO:0046051 10 9 0,000 0,04564201 0,09964559 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04564201 0,09955663 ! artery development GO:0060840 25 9 0,000 0,04564201 0,09946781 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04564201 0,09937916 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04564201 0,09929067 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04564201 0,09920233 ! equilibrioception GO:0050957 20 9 0,000 0,04564201 0,09911415 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04564201 0,09902613 ! chemosensory behavior GO:0007635 21 9 0,000 0,04564201 0,09893826 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04564201 0,09885055 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04564201 0,09876299 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04564201 0,09867559 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04564201 0,09858835 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04564201 0,09850125 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04564201 0,09841432 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04564201 0,09832753 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04564201 0,0982409 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04564201 0,09815442 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04564201 0,09806809 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04564201 0,09798192 ! protein targeting to ER GO:0045047 25 9 0,000 0,04564201 0,09789589 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04564201 0,09781002 ! T cell selection GO:0045058 27 9 0,000 0,04564201 0,09772429 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04564201 0,09763872 ! glycine catabolic process GO:0006546 15 9 0,000 0,04564201 0,0975533 ! endosome organization GO:0007032 20 9 0,000 0,04564201 0,09746802 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04564201 0,0973829 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04564201 0,09729792 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04564201 0,0972131 ! mannose metabolic process GO:0006013 13 9 0,000 0,04564201 0,09712841 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04564201 0,09704388 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04564201 0,0969595 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04564201 0,09687526 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04564201 0,09679116 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04564201 0,09670722 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04564201 0,09662341 ! retinol metabolic process GO:0042572 20 9 0,000 0,04564201 0,09653976 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04564201 0,09645625 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04564201 0,09637288 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04564201 0,09628965 ! macrophage differentiation GO:0030225 15 9 0,000 0,04564201 0,09620657 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04564201 0,09612364 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04564201 0,09604084 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04564201 0,09595819 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04564201 0,09587568 ! response to amine stimulus GO:0014075 13 9 0,000 0,04564201 0,09579332 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04564201 0,09571109 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04564201 0,09562901 ! erythrocyte development GO:0048821 17 9 0,000 0,04564201 0,09554706 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04564201 0,09546526 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04564201 0,09538359 ! renal water homeostasis GO:0003091 15 9 0,000 0,04564201 0,09530207 ! postreplication repair GO:0006301 25 9 0,000 0,04564201 0,09522068 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04564201 0,09513944 ! icosanoid secretion GO:0032309 15 9 0,000 0,04564201 0,09505833 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04564201 0,09497736 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04564201 0,09489653 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04564201 0,09481583 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04564201 0,09473528 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04564201 0,09465486 ! sterol catabolic process GO:0016127 14 9 0,000 0,04564201 0,09457457 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04564201 0,09449442 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04564201 0,09441441 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04564201 0,09433453 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04564201 0,09425479 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04564201 0,09417519 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04564201 0,09409571 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04564201 0,09401637 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04564201 0,09393717 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04564201 0,0938581 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04564201 0,09377916 ! purine base metabolic process GO:0006144 25 9 0,000 0,04564201 0,09370035 ! pigment granule transport GO:0051904 17 9 0,000 0,04564201 0,09362168 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04564201 0,09354314 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04564201 0,09346473 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04564201 0,09338645 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04564201 0,0933083 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04564201 0,09323028 ! mitochondrion localization GO:0051646 18 9 0,000 0,04564201 0,0931524 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,04606476 0,09393673 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,04732437 0,09642488 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 1,000 0,04732437 0,09634453 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,04859651 0,09885201 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,04859651 0,09876977 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,04859651 0,09868767 ! lung development GO:0030324 165 69 1,000 0,04988101 0,10121205 ! single fertilization GO:0007338 83 69 1,000 0,04988101 0,10112805 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05058367 0,10246757 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05058367 0,10238268 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05058367 0,10229793 ! associative learning GO:0008306 21 10 0,000 0,05058367 0,10221331 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05058367 0,10212884 ! phosphate transport GO:0006817 24 10 0,000 0,05058367 0,1020445 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05058367 0,10196031 ! CTP metabolic process GO:0046036 11 10 0,000 0,05058367 0,10187625 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05058367 0,10179233 ! GTP metabolic process GO:0046039 11 10 0,000 0,05058367 0,10170856 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05058367 0,10162491 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05058367 0,10154141 ! social behavior GO:0035176 29 10 0,000 0,05058367 0,10145804 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05058367 0,10137481 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05058367 0,10129172 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05058367 0,10120876 ! androgen metabolic process GO:0008209 17 10 0,000 0,05058367 0,10112594 ! phospholipid efflux GO:0033700 19 10 0,000 0,05058367 0,10104325 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05058367 0,1009607 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05058367 0,10087828 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05058367 0,100796 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05058367 0,10071385 ! pathogenesis GO:0009405 17 10 0,000 0,05058367 0,10063184 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05058367 0,10054995 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05058367 0,10046821 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05058367 0,10038659 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05058367 0,10030511 ! endoderm development GO:0007492 18 10 0,000 0,05058367 0,10022376 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05058367 0,10014254 ! arginine catabolic process GO:0006527 17 10 0,000 0,05058367 0,10006145 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05058367 0,0999805 ! proline metabolic process GO:0006560 13 10 0,000 0,05058367 0,09989967 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05058367 0,09981898 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05058367 0,09973841 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05058367 0,09965798 ! V(D)J recombination GO:0033151 34 10 0,000 0,05058367 0,09957767 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05058367 0,0994975 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05058367 0,09941745 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05058367 0,09933754 ! B cell proliferation GO:0042100 19 10 0,000 0,05058367 0,09925775 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05058367 0,09917809 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05058367 0,09909855 ! multicellular organism growth GO:0035264 19 10 0,000 0,05058367 0,09901915 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05058367 0,09893987 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05058367 0,09886072 ! ruffle organization GO:0031529 17 10 0,000 0,05058367 0,09878169 ! epithelial cell development GO:0002064 21 10 0,000 0,05058367 0,09870279 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05058367 0,09862402 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05058367 0,09854537 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05058367 0,09846685 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05058367 0,09838845 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05058367 0,09831018 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05058367 0,09823203 ! motor axon guidance GO:0008045 22 10 0,000 0,05058367 0,09815401 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05058367 0,09807611 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05058367 0,09799833 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05058367 0,09792068 ! brain morphogenesis GO:0048854 23 10 0,000 0,05058367 0,09784315 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05058367 0,09776574 ! segment specification GO:0007379 15 10 0,000 0,05058367 0,09768845 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05058367 0,09761129 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05058367 0,09753425 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05058367 0,09745733 ! response to dsRNA GO:0043331 23 10 0,000 0,05058367 0,09738053 ! DNA ligation GO:0006266 18 10 0,000 0,05058367 0,09730385 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05058367 0,0972273 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05058367 0,09715086 ! melanosome localization GO:0032400 16 10 0,000 0,05058367 0,09707454 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05058367 0,09699835 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05058367 0,09692227 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05058367 0,09684631 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05058367 0,09677047 ! induction of an organ GO:0001759 17 10 0,000 0,05058367 0,09669475 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05058367 0,09661915 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05058367 0,09654367 ! protein sumoylation GO:0016925 17 10 0,000 0,05058367 0,0964683 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05058367 0,09639305 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05058367 0,09631792 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05058367 0,09624291 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05058367 0,09616801 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05058367 0,09609323 ! salivary gland development GO:0007431 28 10 0,000 0,05058367 0,09601857 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05058367 0,09594402 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05058367 0,09586958 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05058367 0,09579527 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05058367 0,09572106 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05058367 0,09564698 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05058367 0,095573 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05058367 0,09549915 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05058367 0,0954254 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05058367 0,09535177 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05058367 0,09527825 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05058367 0,09520485 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05058367 0,09513156 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05058367 0,09505838 ! blastocyst formation GO:0001825 18 10 0,000 0,05058367 0,09498531 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05058367 0,09491236 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05058367 0,09483952 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05058367 0,09476679 ! response to nicotine GO:0035094 20 10 0,000 0,05058367 0,09469417 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05058367 0,09462166 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05058367 0,09454927 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,05248646 0,09803091 ! appendage morphogenesis GO:0035107 150 72 1,000 0,05380709 0,10042073 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 0,05380709 0,10034407 ! actin filament organization GO:0007015 167 72 1,000 0,05380709 0,10026753 ! appendage development GO:0048736 151 73 1,000 0,05513946 0,10267202 GO:0060173|limb development, ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05549988 0,10326443 ! respiratory burst GO:0045730 17 11 0,000 0,05549988 0,10318584 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05549988 0,10310737 ! neuron fate specification GO:0048665 18 11 0,000 0,05549988 0,10302902 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05549988 0,10295079 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05549988 0,10287268 ! thyroid gland development GO:0030878 26 11 0,000 0,05549988 0,10279469 ! synapsis GO:0007129 14 11 0,000 0,05549988 0,10271681 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05549988 0,10263906 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05549988 0,10256142 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05549988 0,1024839 ! response to pain GO:0048265 27 11 0,000 0,05549988 0,10240649 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05549988 0,1023292 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05549988 0,10225203 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05549988 0,10217498 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05549988 0,10209804 ! bone resorption GO:0045453 16 11 0,000 0,05549988 0,10202122 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05549988 0,10194451 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,05549988 0,10186792 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05549988 0,10179144 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05549988 0,10171508 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05549988 0,10163883 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05549988 0,10156269 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05549988 0,10148667 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05549988 0,10141077 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05549988 0,10133497 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05549988 0,10125929 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05549988 0,10118373 ! UV protection GO:0009650 20 11 0,000 0,05549988 0,10110827 ! adult heart development GO:0007512 16 11 0,000 0,05549988 0,10103293 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05549988 0,1009577 ! temperature homeostasis GO:0001659 18 11 0,000 0,05549988 0,10088259 ! behavioral fear response GO:0001662 27 11 0,000 0,05549988 0,10080758 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05549988 0,10073269 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05549988 0,1006579 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05549988 0,10058323 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05549988 0,10050867 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05549988 0,10043422 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05549988 0,10035988 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05549988 0,10028565 ! regulation of organ growth GO:0046620 14 11 0,000 0,05549988 0,10021153 ! pigment granule localization GO:0051875 20 11 0,000 0,05549988 0,10013752 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05549988 0,10006361 ! vasoconstriction GO:0042310 20 11 0,000 0,05549988 0,09998982 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05549988 0,09991614 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05549988 0,09984256 ! embryonic axis specification GO:0000578 19 11 0,000 0,05549988 0,09976909 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05549988 0,09969573 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05549988 0,09962248 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05549988 0,09954934 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05549988 0,0994763 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05549988 0,09940337 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05549988 0,09933055 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05549988 0,09925783 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05549988 0,09918522 ! prophase GO:0051324 17 11 0,000 0,05549988 0,09911272 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05549988 0,09904032 ! nucleosome positioning GO:0016584 15 11 0,000 0,05549988 0,09896803 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05549988 0,09889584 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05549988 0,09882376 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05549988 0,09875178 ! apical protein localization GO:0045176 18 11 0,000 0,05549988 0,09867991 ! acid secretion GO:0046717 20 11 0,000 0,05549988 0,09860814 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05549988 0,09853648 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05549988 0,09846492 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05549988 0,09839347 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05549988 0,09832211 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05549988 0,09825087 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05549988 0,09817972 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05549988 0,09810868 ! cholesterol efflux GO:0033344 21 11 0,000 0,05549988 0,09803774 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05549988 0,0979669 ! oocyte development GO:0048599 20 11 0,000 0,05549988 0,09789617 ! germ cell migration GO:0008354 26 11 0,000 0,05549988 0,09782554 ! embryonic gut development GO:0048566 19 11 0,000 0,05549988 0,09775501 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05549988 0,09768458 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05549988 0,09761425 ! activation of innate immune response GO:0002218 16 11 0,000 0,05549988 0,09754403 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05549988 0,0974739 ! lysogeny GO:0030069 22 11 0,000 0,05549988 0,09740388 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05549988 0,09733395 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05549988 0,09726413 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05549988 0,09719441 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05549988 0,09712478 ! nucleus localization GO:0051647 22 11 0,000 0,05549988 0,09705526 ! regulation of caspase activity GO:0043281 136 74 1,000 0,05648339 0,09870453 ! respiratory system development GO:0060541 175 74 1,000 0,05648339 0,09863398 ! organelle localization GO:0051640 155 74 1,000 0,05648339 0,09856352 ! transition metal ion transport GO:0000041 143 75 1,000 0,05783875 0,10085658 ! reproductive structure development GO:0048608 131 75 1,000 0,05783875 0,10078464 ! axon guidance GO:0007411 162 75 1,000 0,05783875 0,10071281 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,05920537 0,10301904 ! regulation of blood pressure GO:0008217 134 76 1,000 0,05920537 0,10294571 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06039077 0,10493218 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06039077 0,1048576 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06039077 0,10478313 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06039077 0,10470876 ! virus-host interaction GO:0019048 30 12 0,000 0,06039077 0,1046345 ! mating GO:0007618 17 12 0,000 0,06039077 0,10456034 ! protein complex disassembly GO:0043241 28 12 0,000 0,06039077 0,10448629 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06039077 0,10441234 ! hippocampus development GO:0021766 29 12 0,000 0,06039077 0,1043385 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06039077 0,10426476 ! T cell proliferation GO:0042098 32 12 0,000 0,06039077 0,10419113 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06039077 0,1041176 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06039077 0,10404418 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06039077 0,10397085 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06039077 0,10389764 ! drug transport GO:0015893 16 12 0,000 0,06039077 0,10382452 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06039077 0,10375151 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06039077 0,1036786 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06039077 0,10360579 ! focal adhesion formation GO:0048041 37 12 0,000 0,06039077 0,10353308 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06039077 0,10346048 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06039077 0,10338798 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06039077 0,10331558 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06039077 0,10324328 ! entry into host cell GO:0030260 34 12 0,000 0,06039077 0,10317108 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06039077 0,10309898 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06039077 0,10302698 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06039077 0,10295509 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06039077 0,10288329 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06039077 0,1028116 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06039077 0,10274 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06039077 0,10266851 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06039077 0,10259711 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06039077 0,10252581 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06039077 0,10245461 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06039077 0,10238351 ! cranial nerve development GO:0021545 23 12 0,000 0,06039077 0,10231251 ! fucose catabolic process GO:0019317 25 12 0,000 0,06039077 0,10224161 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06039077 0,1021708 ! histone acetylation GO:0016573 27 12 0,000 0,06039077 0,1021001 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06039077 0,10202949 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06039077 0,10195898 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06039077 0,10188856 ! zymogen activation GO:0031638 18 12 0,000 0,06039077 0,10181825 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06039077 0,10174803 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06039077 0,10167791 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06039077 0,10160788 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06039077 0,10153795 ! oocyte differentiation GO:0009994 21 12 0,000 0,06039077 0,10146812 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06039077 0,10139838 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06039077 0,10132874 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06039077 0,10125919 ! defense response to fungus GO:0050832 15 12 0,000 0,06039077 0,10118974 ! developmental induction GO:0031128 22 12 0,000 0,06039077 0,10112038 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06039077 0,10105112 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06039077 0,10098196 ! response to cold GO:0009409 17 12 0,000 0,06039077 0,10091289 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06039077 0,10084391 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06039077 0,10077503 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,06058311 0,10102699 ! regulation of catabolic process GO:0009894 173 77 1,000 0,06058311 0,10095808 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,06197182 0,10320187 ! fertilization GO:0009566 99 78 1,000 0,06197182 0,10313157 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06197182 0,10306137 ! blood coagulation GO:0007596 151 79 1,000 0,06337134 0,10531713 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,06337134 0,10524553 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,06337134 0,10517403 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,06478153 0,10744146 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06525647 0,10815573 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06525647 0,10808241 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06525647 0,10800918 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06525647 0,10793605 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06525647 0,10786302 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06525647 0,10779009 ! peroxisomal transport GO:0043574 28 13 0,000 0,06525647 0,10771726 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06525647 0,10764453 ! cartilage condensation GO:0001502 22 13 0,000 0,06525647 0,1075719 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06525647 0,10749936 ! organelle fusion GO:0048284 36 13 0,000 0,06525647 0,10742692 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06525647 0,10735458 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06525647 0,10728234 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06525647 0,10721019 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06525647 0,10713814 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06525647 0,10706619 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06525647 0,10699433 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06525647 0,10692257 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06525647 0,1068509 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06525647 0,10677934 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06525647 0,10670786 ! methionine metabolic process GO:0006555 31 13 0,000 0,06525647 0,10663649 ! plasma membrane organization GO:0007009 27 13 0,000 0,06525647 0,10656521 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06525647 0,10649402 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06525647 0,10642293 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06525647 0,10635193 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06525647 0,10628103 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06525647 0,10621023 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06525647 0,10613951 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06525647 0,1060689 ! exocrine system development GO:0035272 34 13 0,000 0,06525647 0,10599837 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06525647 0,10592794 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06525647 0,1058576 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06525647 0,10578736 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06525647 0,10571721 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06525647 0,10564715 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06525647 0,10557719 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06525647 0,10550731 ! protein homotetramerization GO:0051289 24 13 0,000 0,06525647 0,10543753 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06525647 0,10536785 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06525647 0,10529825 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06525647 0,10522875 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06525647 0,10515933 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06525647 0,10509001 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06525647 0,10502078 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06525647 0,10495165 ! histone methylation GO:0016571 29 13 0,000 0,06525647 0,1048826 ! chromatin silencing GO:0006342 29 13 0,000 0,06525647 0,10481364 ! gland morphogenesis GO:0022612 31 13 0,000 0,06525647 0,10474478 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06525647 0,104676 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06525647 0,10460732 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06525647 0,10453872 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06525647 0,10447022 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06525647 0,1044018 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06525647 0,10433348 ! spleen development GO:0048536 24 13 0,000 0,06525647 0,10426524 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06525647 0,10419709 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06525647 0,10412903 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06525647 0,10406106 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06525647 0,10399318 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06525647 0,10392539 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06525647 0,10385769 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06525647 0,10379007 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06525647 0,10372254 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06525647 0,1036551 ! insulin secretion GO:0030073 24 13 0,000 0,06525647 0,10358775 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06525647 0,10352049 ! acrosome reaction GO:0007340 19 13 0,000 0,06525647 0,10345331 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06525647 0,10338622 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06525647 0,10331922 ! muscle cell differentiation GO:0042692 178 81 1,000 0,06620224 0,10474874 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,06763332 0,10694382 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,06763332 0,10687465 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,06907464 0,10908167 ! response to drug GO:0042493 149 83 1,000 0,06907464 0,10901121 ! rRNA transcription GO:0009303 28 14 0,000 0,07009711 0,11055341 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07009711 0,11048209 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07009711 0,11041085 ! water transport GO:0006833 21 14 0,000 0,07009711 0,11033971 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07009711 0,11026866 ! non-recombinational repair GO:0000726 29 14 0,000 0,07009711 0,11019771 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07009711 0,11012684 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07009711 0,11005606 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07009711 0,10998538 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07009711 0,10991479 ! lipid localization GO:0010876 32 14 0,000 0,07009711 0,10984428 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07009711 0,10977387 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07009711 0,10970355 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07009711 0,10963331 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07009711 0,10956317 ! arginine metabolic process GO:0006525 21 14 0,000 0,07009711 0,10949312 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07009711 0,10942315 ! regulation of heart rate GO:0002027 25 14 0,000 0,07009711 0,10935328 ! fear response GO:0042596 34 14 0,000 0,07009711 0,10928349 ! organic alcohol transport GO:0015850 29 14 0,000 0,07009711 0,1092138 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07009711 0,10914419 ! embryo implantation GO:0007566 30 14 0,000 0,07009711 0,10907467 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07009711 0,10900524 ! bone mineralization GO:0030282 18 14 0,000 0,07009711 0,1089359 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07009711 0,10886665 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07009711 0,10879748 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07009711 0,1087284 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07009711 0,10865941 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07009711 0,10859051 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07009711 0,1085217 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07009711 0,10845297 ! ribosome assembly GO:0042255 18 14 0,000 0,07009711 0,10838433 ! cerebellum development GO:0021549 23 14 0,000 0,07009711 0,10831577 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07009711 0,1082473 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07009711 0,10817892 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07009711 0,10811063 ! response to gamma radiation GO:0010332 30 14 0,000 0,07009711 0,10804242 ! NADP metabolic process GO:0006739 24 14 0,000 0,07009711 0,1079743 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07009711 0,10790626 ! oxygen transport GO:0015671 22 14 0,000 0,07009711 0,10783831 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07009711 0,10777044 ! male genitalia development GO:0030539 26 14 0,000 0,07009711 0,10770266 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07009711 0,10763497 ! regulation of axon extension GO:0030516 43 14 0,000 0,07009711 0,10756736 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07009711 0,10749983 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07009711 0,10743239 ! response to metal ion GO:0010038 158 84 1,000 0,07052605 0,10802203 ! response to nutrient GO:0007584 135 84 1,000 0,07052605 0,10795435 ! digestion GO:0007586 130 84 1,000 0,07052605 0,10788675 ! regulation of ligase activity GO:0051340 147 84 1,000 0,07052605 0,10781924 ! hemostasis GO:0007599 165 85 1,000 0,07198741 0,10998451 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,07198741 0,10991577 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,07198741 0,10984712 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,07345857 0,11202203 ! regulation of lyase activity GO:0051339 169 86 1,000 0,07345857 0,11195214 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07345857 0,11188235 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07491282 0,11402618 ! lactation GO:0007595 30 15 0,000 0,07491282 0,11395518 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07491282 0,11388426 ! reproductive cellular process GO:0048610 22 15 0,000 0,07491282 0,11381344 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07491282 0,1137427 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07491282 0,11367206 ! superoxide anion generation GO:0042554 22 15 0,000 0,07491282 0,1136015 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07491282 0,11353102 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07491282 0,11346064 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07491282 0,11339034 ! copper ion transport GO:0006825 22 15 0,000 0,07491282 0,11332013 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07491282 0,11325001 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07491282 0,11317997 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07491282 0,11311002 ! sulfate transport GO:0008272 27 15 0,000 0,07491282 0,11304016 ! response to cAMP GO:0051591 25 15 0,000 0,07491282 0,11297038 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07491282 0,11290069 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07491282 0,11283108 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07491282 0,11276156 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07491282 0,11269213 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07491282 0,11262278 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07491282 0,11255351 ! vesicle coating GO:0006901 38 15 0,000 0,07491282 0,11248433 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07491282 0,11241524 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07491282 0,11234623 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07491282 0,11227731 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07491282 0,11220847 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07491282 0,11213971 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07491282 0,11207104 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07491282 0,11200246 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07491282 0,11193395 ! histone deacetylation GO:0016575 24 15 0,000 0,07491282 0,11186553 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07491282 0,1117972 ! water homeostasis GO:0030104 28 15 0,000 0,07491282 0,11172895 ! cofactor transport GO:0051181 30 15 0,000 0,07491282 0,11166078 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07491282 0,11159269 ! muscle maintenance GO:0046716 26 15 0,000 0,07491282 0,11152469 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07491282 0,11145677 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07491282 0,11138893 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07491282 0,11132118 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07491282 0,1112535 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07491282 0,11118591 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07491282 0,1111184 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07491282 0,11105098 ! actin filament polymerization GO:0030041 27 15 0,000 0,07491282 0,11098363 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07491282 0,11091637 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,07792952 0,11531303 ! regulation of neurological system process GO:0031644 175 89 1,000 0,07792952 0,11524322 ! response to inorganic substance GO:0010035 173 90 1,000 0,07943853 0,1174037 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07970372 0,11772442 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07970372 0,11765329 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07970372 0,11758224 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07970372 0,11751128 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07970372 0,1174404 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07970372 0,11736962 ! bone remodeling GO:0046849 28 16 0,000 0,07970372 0,11729891 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,07970372 0,11722829 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07970372 0,11715776 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07970372 0,11708731 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07970372 0,11701694 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07970372 0,11694666 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07970372 0,11687647 ! startle response GO:0001964 28 16 0,000 0,07970372 0,11680635 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07970372 0,11673633 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07970372 0,11666638 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07970372 0,11659652 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07970372 0,11652675 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07970372 0,11645705 ! pituitary gland development GO:0021983 30 16 0,000 0,07970372 0,11638744 ! response to osmotic stress GO:0006970 27 16 0,000 0,07970372 0,11631792 ! lysosomal transport GO:0007041 31 16 0,000 0,07970372 0,11624847 ! fructose metabolic process GO:0006000 25 16 0,000 0,07970372 0,11617911 ! L-amino acid transport GO:0015807 33 16 0,000 0,07970372 0,11610983 ! stem cell development GO:0048864 46 16 0,000 0,07970372 0,11604064 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07970372 0,11597153 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07970372 0,11590249 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07970372 0,11583355 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07970372 0,11576468 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07970372 0,1156959 ! axon cargo transport GO:0008088 46 16 0,000 0,07970372 0,11562719 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07970372 0,11555857 ! DNA replication initiation GO:0006270 28 16 0,000 0,07970372 0,11549003 ! neuron recognition GO:0008038 40 16 0,000 0,07970372 0,11542157 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07970372 0,11535319 ! tissue regeneration GO:0042246 27 16 0,000 0,07970372 0,1152849 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07970372 0,11521668 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07970372 0,11514855 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,07970372 0,11508049 ! biomineral formation GO:0031214 22 16 0,000 0,07970372 0,11501252 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07970372 0,11494462 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07970372 0,11487681 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07970372 0,11480908 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07970372 0,11474142 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07970372 0,11467385 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07970372 0,11460635 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07970372 0,11453894 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07970372 0,1144716 ! peptide hormone processing GO:0016486 27 16 0,000 0,07970372 0,11440434 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,08095666 0,11613453 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,08095666 0,11606638 ! gland development GO:0048732 220 91 1,000 0,08095666 0,11599831 ! bone development GO:0060348 206 92 1,000 0,08248378 0,11811715 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08446995 0,1208905 ! metencephalon development GO:0022037 32 17 0,000 0,08446995 0,12081972 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08446995 0,12074903 ! filopodium assembly GO:0046847 42 17 0,000 0,08446995 0,12067841 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08446995 0,12060788 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08446995 0,12053743 ! glial cell development GO:0021782 28 17 0,000 0,08446995 0,12046707 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08446995 0,12039678 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08446995 0,12032658 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08446995 0,12025646 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08446995 0,12018642 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08446995 0,12011646 ! myoblast differentiation GO:0045445 50 17 0,000 0,08446995 0,12004659 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08446995 0,11997679 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,08446995 0,11990708 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08446995 0,11983745 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08446995 0,1197679 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08446995 0,11969842 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08446995 0,11962903 ! membrane budding GO:0006900 42 17 0,000 0,08446995 0,11955972 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08446995 0,11949049 ! regulation of protein binding GO:0043393 33 17 0,000 0,08446995 0,11942135 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08446995 0,11935228 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08446995 0,11928329 ! genitalia development GO:0048806 32 17 0,000 0,08446995 0,11921438 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08446995 0,11914555 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08446995 0,11907679 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08446995 0,11900812 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08446995 0,11893953 ! steroid catabolic process GO:0006706 34 17 0,000 0,08446995 0,11887102 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08446995 0,11880258 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08446995 0,11873423 ! gas transport GO:0015669 26 17 0,000 0,08446995 0,11866595 ! organic cation transport GO:0015695 32 17 0,000 0,08446995 0,11859775 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08446995 0,11852963 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08446995 0,11846159 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08446995 0,11839362 ! regulation of membrane potential GO:0042391 179 94 1,000 0,08556445 0,11985892 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,08711774 0,12196484 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,08711774 0,12189499 ! sex differentiation GO:0007548 171 96 1,000 0,0886795 0,12400917 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08921162 0,12468192 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08921162 0,12461063 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08921162 0,12453943 ! limbic system development GO:0021761 40 18 0,000 0,08921162 0,1244683 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08921162 0,12439726 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08921162 0,1243263 ! adult walking behavior GO:0007628 36 18 0,000 0,08921162 0,12425542 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08921162 0,12418461 ! heart looping GO:0001947 34 18 0,000 0,08921162 0,12411389 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08921162 0,12404326 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08921162 0,1239727 ! centrosome cycle GO:0007098 26 18 0,000 0,08921162 0,12390222 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08921162 0,12383182 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08921162 0,1237615 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08921162 0,12369126 ! glycine metabolic process GO:0006544 30 18 0,000 0,08921162 0,1236211 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08921162 0,12355102 ! response to retinoic acid GO:0032526 31 18 0,000 0,08921162 0,12348102 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08921162 0,1234111 ! DNA integration GO:0015074 32 18 0,000 0,08921162 0,12334126 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08921162 0,12327149 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08921162 0,12320181 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08921162 0,1231322 ! neural crest cell migration GO:0001755 41 18 0,000 0,08921162 0,12306268 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08921162 0,12299323 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08921162 0,12292386 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08921162 0,12285457 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08921162 0,12278535 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,08921162 0,12271622 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08921162 0,12264716 ! detection of bacterium GO:0016045 22 18 0,000 0,08921162 0,12257818 ! nerve development GO:0021675 34 18 0,000 0,08921162 0,12250927 ! defense response to virus GO:0051607 43 18 0,000 0,08921162 0,12244045 ! microspike assembly GO:0030035 46 18 0,000 0,08921162 0,1223717 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08921162 0,12230303 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,08921162 0,12223444 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,0918279 0,12574863 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09392888 0,12855364 ! positive regulation of translation GO:0045727 31 19 0,000 0,09392888 0,12848166 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09392888 0,12840976 ! neuron maturation GO:0042551 46 19 0,000 0,09392888 0,12833794 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09392888 0,12826621 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09392888 0,12819455 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09392888 0,12812297 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09392888 0,12805148 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09392888 0,12798006 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09392888 0,12790872 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09392888 0,12783746 ! cerebral cortex development GO:0021987 40 19 0,000 0,09392888 0,12776628 ! response to vitamin A GO:0033189 32 19 0,000 0,09392888 0,12769518 ! heme metabolic process GO:0042168 40 19 0,000 0,09392888 0,12762416 ! neuromuscular junction development GO:0007528 43 19 0,000 0,09392888 0,12755322 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09392888 0,12748236 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09392888 0,12741157 ! response to fungus GO:0009620 26 19 0,000 0,09392888 0,12734087 ! peptide cross-linking GO:0018149 39 19 0,000 0,09392888 0,12727024 ! protein export from nucleus GO:0006611 40 19 0,000 0,09392888 0,12719969 ! heart process GO:0003015 32 19 0,000 0,09392888 0,12712922 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09392888 0,12705883 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09392888 0,12698851 ! visual learning GO:0008542 38 19 0,000 0,09392888 0,12691828 ! cellular pigmentation GO:0033059 37 19 0,000 0,09392888 0,12684812 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09392888 0,12677804 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09392888 0,12670803 ! vitamin transport GO:0051180 31 19 0,000 0,09392888 0,1266381 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09392888 0,12656825 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09392888 0,12649848 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09392888 0,12642878 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09392888 0,12635916 ! cilium assembly GO:0042384 38 19 0,000 0,09392888 0,12628962 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09392888 0,12622016 ! protein secretion GO:0009306 45 20 0,000 0,09862183 0,13245361 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09862183 0,13238084 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09862183 0,13230814 ! skin development GO:0043588 42 20 0,000 0,09862183 0,13223552 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09862183 0,13216299 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09862183 0,13209053 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,09862183 0,13201815 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09862183 0,13194585 ! response to vitamin GO:0033273 36 20 0,000 0,09862183 0,13187363 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09862183 0,13180149 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,09862183 0,13172943 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09862183 0,13165744 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09862183 0,13158554 ! response to alkaloid GO:0043279 38 20 0,000 0,09862183 0,13151371 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09862183 0,13144197 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,09862183 0,1313703 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09862183 0,1312987 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09862183 0,13122719 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,09862183 0,13115576 ! actin filament bundle formation GO:0051017 47 20 0,000 0,09862183 0,1310844 ! body fluid secretion GO:0007589 33 20 0,000 0,09862183 0,13101312 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09862183 0,13094191 ! peptide secretion GO:0002790 38 20 0,000 0,09862183 0,13087079 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09862183 0,13079974 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09862183 0,13072877 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09862183 0,13065788 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09862183 0,13058706 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09862183 0,13051632 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09862183 0,13044565 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09862183 0,13037507 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09862183 0,13030456 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09862183 0,13023412 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09862183 0,13016376 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09862183 0,13009348 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09862183 0,13002327 ! regulation of cell killing GO:0031341 46 21 0,000 0,1032906 0,13610515 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,1032906 0,13603177 ! hormone secretion GO:0046879 39 21 0,000 0,1032906 0,13595848 ! cAMP metabolic process GO:0046058 41 21 0,000 0,1032906 0,13588527 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,1032906 0,13581213 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,1032906 0,13573908 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,1032906 0,1356661 ! ovarian follicle development GO:0001541 39 21 0,000 0,1032906 0,1355932 ! smooth muscle contraction GO:0006939 48 21 0,000 0,1032906 0,13552038 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,1032906 0,13544763 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,1032906 0,13537497 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,1032906 0,13530238 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,1032906 0,13522987 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,1032906 0,13515744 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,1032906 0,13508509 ! diencephalon development GO:0021536 36 21 0,000 0,1032906 0,13501281 ! collagen fibril organization GO:0030199 62 21 0,000 0,1032906 0,13494061 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,1032906 0,13486849 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,1032906 0,13479644 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,1032906 0,13472447 ! collagen catabolic process GO:0030574 29 21 0,000 0,1032906 0,13465258 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,1032906 0,13458077 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,1032906 0,13450903 ! sperm-egg recognition GO:0035036 23 21 0,000 0,1032906 0,13443737 ! actin filament-based movement GO:0030048 47 21 0,000 0,1032906 0,13436578 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,1032906 0,13429427 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,10793533 0,14025851 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10793533 0,14018395 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10793533 0,14010946 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10793533 0,14003505 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10793533 0,13996072 ! microtubule-based transport GO:0010970 59 22 0,000 0,10793533 0,13988647 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,10793533 0,1398123 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,10793533 0,13973821 ! vacuolar transport GO:0007034 41 22 0,000 0,10793533 0,1396642 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10793533 0,13959026 ! fucose metabolic process GO:0006004 44 22 0,000 0,10793533 0,1395164 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,10793533 0,13944262 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10793533 0,13936892 ! cell aging GO:0007569 48 22 0,000 0,10793533 0,1392953 ! stem cell differentiation GO:0048863 57 22 0,000 0,10793533 0,13922175 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10793533 0,13914829 ! cytolysis GO:0019835 27 22 0,000 0,10793533 0,1390749 ! renal system process GO:0003014 42 22 0,000 0,10793533 0,13900158 ! vasodilation GO:0042311 40 22 0,000 0,10793533 0,13892835 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10793533 0,13885519 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10793533 0,13878211 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,10793533 0,1387091 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,10793533 0,13863617 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10793533 0,13856332 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10793533 0,13849055 ! sarcomere organization GO:0045214 32 22 0,000 0,10793533 0,13841785 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,10793533 0,13834523 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,10793533 0,13827268 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10793533 0,13820021 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10793533 0,13812782 ! gut development GO:0048565 44 22 0,000 0,10793533 0,1380555 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10793533 0,13798326 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10793533 0,13791109 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,11255612 0,14373999 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11255612 0,14366489 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11255612 0,14358987 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11255612 0,14351493 ! gluconeogenesis GO:0006094 38 23 0,000 0,11255612 0,14344007 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11255612 0,14336528 ! viral genome replication GO:0019079 44 23 0,000 0,11255612 0,14329057 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11255612 0,14321594 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11255612 0,14314139 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11255612 0,14306691 ! regeneration GO:0031099 42 23 0,000 0,11255612 0,14299251 ! axis specification GO:0009798 43 23 0,000 0,11255612 0,14291819 ! visual behavior GO:0007632 46 23 0,000 0,11255612 0,14284395 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11255612 0,14276978 ! response to ethanol GO:0045471 47 23 0,000 0,11255612 0,1426957 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11255612 0,14262168 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,11255612 0,14254775 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11255612 0,14247389 ! peroxisome organization GO:0007031 43 23 0,000 0,11255612 0,14240011 ! lysosome organization GO:0007040 47 23 0,000 0,11255612 0,1423264 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11255612 0,14225277 ! vesicle targeting GO:0006903 49 23 0,000 0,11255612 0,14217922 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,11255612 0,14210574 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11255612 0,14203234 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11255612 0,14195901 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11255612 0,14188576 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11255612 0,14181259 ! DNA modification GO:0006304 36 23 0,000 0,11255612 0,14173949 ! fatty acid transport GO:0015908 47 23 0,000 0,11255612 0,14166646 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11255612 0,14159351 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11255612 0,14152064 ! hormone transport GO:0009914 41 23 0,000 0,11255612 0,14144784 ! cell-cell recognition GO:0009988 28 23 0,000 0,11255612 0,14137512 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11255612 0,14130247 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11255612 0,1412299 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11255612 0,1411574 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11715311 0,14684713 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11715311 0,14677182 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,11715311 0,14669659 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,11715311 0,14662144 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11715311 0,14654637 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11715311 0,14647137 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11715311 0,14639645 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11715311 0,1463216 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11715311 0,14624683 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11715311 0,14617214 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11715311 0,14609753 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11715311 0,14602299 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11715311 0,14594852 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11715311 0,14587413 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11715311 0,14579982 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,11715311 0,14572559 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11715311 0,14565143 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11715311 0,14557734 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11715311 0,14550333 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11715311 0,1454294 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11715311 0,14535554 ! membrane depolarization GO:0051899 45 24 0,000 0,11715311 0,14528175 ! pallium development GO:0021543 56 24 0,000 0,11715311 0,14520804 ! oogenesis GO:0048477 44 24 0,000 0,11715311 0,14513441 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11715311 0,14506085 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11715311 0,14498736 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11715311 0,14491395 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11715311 0,14484061 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11715311 0,14476735 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11715311 0,14469416 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11715311 0,14462105 ! regulation of amine transport GO:0051952 41 24 0,000 0,11715311 0,14454801 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,11715311 0,14447504 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,12172642 0,15003917 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12172642 0,14996351 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12172642 0,14988792 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12172642 0,14981241 ! keratinization GO:0031424 37 25 0,000 0,12172642 0,14973698 ! vasculogenesis GO:0001570 49 25 0,000 0,12172642 0,14966162 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,12172642 0,14958634 ! vacuole organization GO:0007033 49 25 0,000 0,12172642 0,14951113 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12172642 0,149436 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,12172642 0,14936094 ! chromosome condensation GO:0030261 48 25 0,000 0,12172642 0,14928596 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12172642 0,14921106 ! interaction with host GO:0051701 66 25 0,000 0,12172642 0,14913623 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12172642 0,14906147 ! immunoglobulin production GO:0002377 62 25 0,000 0,12172642 0,14898679 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12172642 0,14891219 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12172642 0,14883766 ! liver development GO:0001889 55 25 0,000 0,12172642 0,1487632 ! protein tetramerization GO:0051262 57 25 0,000 0,12172642 0,14868882 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12627616 0,15416925 ! initiation of viral infection GO:0019059 60 26 0,000 0,12627616 0,15409224 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12627616 0,15401531 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12627616 0,15393845 ! molting cycle process GO:0022404 52 26 0,000 0,12627616 0,15386168 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12627616 0,15378498 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12627616 0,15370835 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12627616 0,1536318 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12627616 0,15355533 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12627616 0,15347894 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12627616 0,15340262 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12627616 0,15332637 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12627616 0,1532502 ! neural crest cell development GO:0014032 59 26 0,000 0,12627616 0,15317411 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12627616 0,1530981 ! negative regulation of cell development GO:0010721 83 26 0,000 0,12627616 0,15302215 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12627616 0,15294629 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12627616 0,1528705 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12627616 0,15279478 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12627616 0,15271914 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12627616 0,15264357 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12627616 0,15256808 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12627616 0,15249267 ! blastocyst development GO:0001824 50 26 0,000 0,12627616 0,15241732 ! telomere organization GO:0032200 46 26 0,000 0,12627616 0,15234206 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12627616 0,15226686 ! neural tube closure GO:0001843 58 26 0,000 0,12627616 0,15219174 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,12627616 0,1521167 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12627616 0,15204173 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12627616 0,15196683 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13080246 0,15733649 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13080246 0,15725906 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13080246 0,15718171 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13080246 0,15710443 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13080246 0,15702723 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13080246 0,15695011 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13080246 0,15687306 ! iron ion transport GO:0006826 65 27 0,000 0,13080246 0,15679608 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13080246 0,15671918 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13080246 0,15664236 ! tube lumen formation GO:0035148 59 27 0,000 0,13080246 0,15656561 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,13080246 0,15648894 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,13080246 0,15641234 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13080246 0,15633582 ! response to toxin GO:0009636 49 27 0,000 0,13080246 0,15625937 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,13080246 0,156183 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13080246 0,1561067 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13080246 0,15603048 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,13530544 0,16132318 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13530544 0,16124449 ! protein amino acid acylation GO:0043543 59 28 0,000 0,13530544 0,16116587 ! vesicle docking GO:0048278 55 28 0,000 0,13530544 0,16108733 ! circadian rhythm GO:0007623 56 28 0,000 0,13530544 0,16100886 ! dendrite development GO:0016358 67 28 0,000 0,13530544 0,16093048 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13530544 0,16085216 ! sperm motility GO:0030317 37 28 0,000 0,13530544 0,16077393 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13530544 0,16069577 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13530544 0,16061769 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13530544 0,16053968 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13530544 0,16046175 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13530544 0,16038389 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13530544 0,16030611 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13530544 0,1602284 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13530544 0,16015077 ! lipid oxidation GO:0034440 48 28 0,000 0,13530544 0,16007322 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13530544 0,15999574 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13530544 0,15991833 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,13978522 0,16513312 ! translational initiation GO:0006413 66 29 0,000 0,13978522 0,16505331 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,13978522 0,16497357 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,13978522 0,16489391 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,13978522 0,16481433 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,13978522 0,16473483 ! primary neural tube formation GO:0014020 61 29 0,000 0,13978522 0,1646554 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,13978522 0,16457605 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,13978522 0,16449677 ! somitogenesis GO:0001756 52 29 0,000 0,13978522 0,16441757 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,13978522 0,16433845 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,13978522 0,1642594 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,13978522 0,16418043 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,13978522 0,16410154 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14424192 0,16925216 ! phenol metabolic process GO:0018958 56 30 0,000 0,14424192 0,16917091 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14424192 0,16908973 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14424192 0,16900863 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14424192 0,16892761 ! sensory perception of taste GO:0050909 41 30 0,000 0,14424192 0,16884667 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14424192 0,16876581 ! acute-phase response GO:0006953 50 30 0,000 0,14424192 0,16868502 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14424192 0,16860431 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14424192 0,16852367 ! myofibril assembly GO:0030239 50 30 0,000 0,14424192 0,16844312 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14424192 0,16836264 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14424192 0,16828224 ! cell fate determination GO:0001709 64 30 0,000 0,14424192 0,16820191 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,14424192 0,16812166 ! phospholipid transport GO:0015914 65 30 0,000 0,14424192 0,16804149 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14424192 0,16796139 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14424192 0,16788137 ! tissue homeostasis GO:0001894 50 30 0,000 0,14424192 0,16780143 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,14424192 0,16772156 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,14867565 0,17279477 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,14867565 0,1727126 GO:0009799|determination of symmetry, ! amino sugar metabolic process GO:0006040 41 31 0,000 0,14867565 0,17263051 ! regulation of innate immune response GO:0045088 57 31 0,000 0,14867565 0,17254851 ! ovulation cycle process GO:0022602 55 31 0,000 0,14867565 0,17246657 ! peptide transport GO:0015833 60 31 0,000 0,14867565 0,17238472 ! male gonad development GO:0008584 56 31 0,000 0,14867565 0,17230294 ! iron ion homeostasis GO:0055072 60 31 0,000 0,14867565 0,17222124 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,14867565 0,17213962 ! natural killer cell activation GO:0030101 50 31 0,000 0,14867565 0,17205808 ! cofactor catabolic process GO:0051187 54 31 0,000 0,14867565 0,17197661 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,14867565 0,17189522 ! eye morphogenesis GO:0048592 65 31 0,000 0,14867565 0,17181391 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,14867565 0,17173267 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15308653 0,17674404 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15308653 0,17666055 ! collagen metabolic process GO:0032963 49 32 0,000 0,15308653 0,17657714 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15308653 0,17649381 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15308653 0,17641056 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15308653 0,17632739 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,15308653 0,17624429 ! muscle cell development GO:0055001 52 32 0,000 0,15308653 0,17616128 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15308653 0,17607834 ! ovulation cycle GO:0042698 57 32 0,000 0,15308653 0,17599548 ! peripheral nervous system development GO:0007422 68 32 0,000 0,15308653 0,1759127 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15308653 0,17582999 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15308653 0,17574736 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,15308653 0,17566481 ! gene silencing GO:0016458 71 32 0,000 0,15308653 0,17558234 ! regulation of pH GO:0006885 56 33 0,000 0,15747468 0,18053057 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15747468 0,18044589 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15747468 0,1803613 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,15747468 0,18027678 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15747468 0,18019234 ! response to ionizing radiation GO:0010212 74 33 0,000 0,15747468 0,18010798 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15747468 0,1800237 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15747468 0,1799395 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15747468 0,17985537 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15747468 0,17977133 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16184022 0,18466869 ! post-embryonic development GO:0009791 76 34 0,000 0,16184022 0,18458247 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16184022 0,18449634 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16184022 0,18441029 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16184022 0,18432432 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16184022 0,18423842 ! cell fate specification GO:0001708 56 34 0,000 0,16184022 0,18415261 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16184022 0,18406688 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16184022 0,18398123 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,16184022 0,18389566 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16618326 0,18874278 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,16618326 0,18865507 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16618326 0,18856745 ! membrane docking GO:0022406 69 35 0,000 0,16618326 0,1884799 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16618326 0,18839244 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16618326 0,18830506 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,16618326 0,18821776 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16618326 0,18813054 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16618326 0,1880434 ! telencephalon development GO:0021537 81 35 0,000 0,16618326 0,18795635 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16618326 0,18786937 ! placenta development GO:0001890 53 35 0,000 0,16618326 0,18778247 ! vesicle localization GO:0051648 70 35 0,000 0,16618326 0,18769566 ! regulation of muscle development GO:0048634 82 36 0,000 0,17050392 0,19248664 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,17050392 0,19239773 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17050392 0,1923089 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17050392 0,19222016 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17050392 0,19213149 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17050392 0,19204291 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,17050392 0,19195441 ! aerobic respiration GO:0009060 56 36 0,000 0,17050392 0,191866 ! cytokine production GO:0001816 68 36 0,000 0,17050392 0,19177766 ! embryonic organ development GO:0048568 67 36 0,000 0,17050392 0,19168941 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17050392 0,19160123 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17050392 0,19151314 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,17480231 0,19625094 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17480231 0,19616079 ! tissue remodeling GO:0048771 78 37 0,000 0,17480231 0,19607073 ! female gonad development GO:0008585 71 37 0,000 0,17480231 0,19598075 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17480231 0,19589085 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,17480231 0,19580103 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,17907855 0,20049904 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,17907855 0,20040719 ! organic anion transport GO:0015711 82 38 0,000 0,17907855 0,20031543 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,17907855 0,20022375 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,17907855 0,20013216 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,17907855 0,20004065 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,17907855 0,19994922 ! spermatid development GO:0007286 69 38 0,000 0,17907855 0,19985788 ! glycogen metabolic process GO:0005977 63 38 0,000 0,17907855 0,19976662 ! pigment metabolic process GO:0042440 87 38 0,000 0,17907855 0,19967544 ! neural tube formation GO:0001841 79 38 0,000 0,17907855 0,19958435 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18333275 0,20423251 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18333275 0,20413943 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,18333275 0,20404643 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18333275 0,20395351 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18333275 0,20386068 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18333275 0,20376793 ! glucan metabolic process GO:0044042 64 39 0,000 0,18333275 0,20367526 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,18756502 0,20828243 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,18756502 0,2081878 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18756502 0,20809325 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,18756502 0,20799879 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,18756502 0,20790442 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,18756502 0,20781013 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19177547 0,21237873 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19177547 0,2122825 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19177547 0,21218636 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19177547 0,21209031 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19177547 0,21199434 ! feeding behavior GO:0007631 69 41 0,000 0,19177547 0,21189846 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,19177547 0,21180266 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,19177547 0,21170695 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19177547 0,21161133 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,19177547 0,21151579 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,19177547 0,21142035 ! RNA modification GO:0009451 64 41 0,000 0,19177547 0,21132498 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19596423 0,21584338 ! ear morphogenesis GO:0042471 64 42 0,000 0,19596423 0,21574611 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19596423 0,21564892 ! T cell differentiation GO:0030217 93 42 0,000 0,19596423 0,21555183 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19596423 0,21545482 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19596423 0,2153579 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19596423 0,21526107 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,19596423 0,21516432 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,19596423 0,21506766 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,20013139 0,21954243 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,20013139 0,21944389 ! regulation of tube size GO:0035150 76 43 0,000 0,20013139 0,21934544 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,20013139 0,21924708 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,20013139 0,21914881 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,20013139 0,21905062 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,20013139 0,21895252 ! segmentation GO:0035282 78 43 0,000 0,20013139 0,21885451 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20013139 0,21875659 ! neuron migration GO:0001764 85 43 0,000 0,20013139 0,21865876 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,20427707 0,22308846 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,20427707 0,22298878 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,20427707 0,22288918 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,20427707 0,22278968 ! hexose transport GO:0008645 68 44 0,000 0,20427707 0,22269027 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,20427707 0,22259094 ! phagocytosis GO:0006909 105 44 0,000 0,20427707 0,2224917 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20427707 0,22239255 ! double-strand break repair GO:0006302 85 44 0,000 0,20427707 0,22229349 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,20840138 0,22668058 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,20840138 0,2265797 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,20840138 0,2264789 ! B cell differentiation GO:0030183 124 45 0,000 0,20840138 0,2263782 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,20840138 0,22627759 ! female gamete generation GO:0007292 71 45 0,000 0,20840138 0,22617707 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,20840138 0,22607663 ! developmental growth GO:0048589 88 45 0,000 0,20840138 0,22597629 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21250443 0,23032313 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21250443 0,23022099 ! glycolysis GO:0006096 71 46 0,000 0,21250443 0,23011894 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,21250443 0,23001698 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21250443 0,22991511 ! neural tube development GO:0021915 91 47 0,000 0,21658633 0,23422771 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,21658633 0,23412407 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22064718 0,23840825 ! mitochondrial transport GO:0006839 94 48 0,000 0,22064718 0,23830286 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,22064718 0,23819755 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,22064718 0,23809234 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,22064718 0,23798722 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,22064718 0,2378822 ! male sex differentiation GO:0046661 93 48 0,000 0,22064718 0,23777727 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22064718 0,23767243 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22064718 0,23756768 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22064718 0,23746302 ! methylation GO:0032259 97 48 0,000 0,22064718 0,23735846 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,2246871 0,24159797 ! JNK cascade GO:0007254 106 49 0,000 0,2246871 0,24149168 ! protein homooligomerization GO:0051260 84 49 0,000 0,2246871 0,24138548 ! regulation of ion transport GO:0043269 86 50 0,000 0,22870619 0,24559526 ! endocrine system development GO:0035270 109 50 0,000 0,22870619 0,24548735 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,22870619 0,24537954 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,22870619 0,24527183 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,22870619 0,2451642 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,22870619 0,24505667 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,22870619 0,24494924 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,23270456 0,24912236 ! viral infectious cycle GO:0019058 104 51 0,000 0,23270456 0,24901324 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23270456 0,24890422 ! peptide metabolic process GO:0006518 80 51 0,000 0,23270456 0,24879529 ! positive regulation of binding GO:0051099 88 52 0,000 0,23668231 0,25293739 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,23668231 0,25282679 ! Notch signaling pathway GO:0007219 111 52 0,000 0,23668231 0,25271629 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,23668231 0,25260589 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,23668231 0,25249558 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,23668231 0,25238537 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,23668231 0,25227525 ! excretion GO:0007588 87 52 0,000 0,23668231 0,25216523 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,23668231 0,25205531 ! histone modification GO:0016570 104 52 0,000 0,23668231 0,25194548 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,23668231 0,25183575 ! amino acid activation GO:0043038 98 52 0,000 0,23668231 0,25172611 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24063955 0,25582351 ! positive regulation of growth GO:0045927 96 53 0,000 0,24063955 0,25571223 ! inner ear development GO:0048839 89 53 0,000 0,24063955 0,25560105 ! chromatin remodeling GO:0006338 122 53 0,000 0,24063955 0,25548997 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24063955 0,25537898 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24063955 0,2552681 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,24063955 0,2551573 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,24457639 0,25921914 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,24457639 0,25910673 ! neuromuscular process GO:0050905 107 54 0,000 0,24457639 0,25899442 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,24457639 0,2588822 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,24457639 0,25877008 ! covalent chromatin modification GO:0016569 115 54 0,000 0,24457639 0,25865806 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,24457639 0,25854614 ! regulation of cell shape GO:0008360 142 54 0,000 0,24457639 0,25843431 ! RNA catabolic process GO:0006401 103 55 0,000 0,24849293 0,26245924 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,24849293 0,26234582 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,24849293 0,26223249 ! cell recognition GO:0008037 98 55 0,000 0,24849293 0,26211927 ! cell maturation GO:0048469 107 55 0,000 0,24849293 0,26200614 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,24849293 0,26189311 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,25238927 0,26588486 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,25238927 0,26577025 ! glucose catabolic process GO:0006007 88 56 0,000 0,25238927 0,26565575 ! RNA elongation GO:0006354 90 56 0,000 0,25238927 0,26554134 ! chloride transport GO:0006821 102 57 0,000 0,25626552 0,26950352 ! muscle fiber development GO:0048747 131 57 0,000 0,25626552 0,26938755 ! regulation of actin filament length GO:0030832 118 58 0,000 0,26012178 0,27332366 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,26012178 0,27320615 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26012178 0,27308875 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26012178 0,27297144 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26012178 0,27285423 ! nuclear export GO:0051168 110 59 0,000 0,26395816 0,27675956 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,26777475 0,2806408 ! regulation of endocytosis GO:0030100 104 60 0,000 0,26777475 0,28052046 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,26777475 0,28040022 ! adult behavior GO:0030534 104 60 0,000 0,26777475 0,28028008 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27157165 0,28413257 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27157165 0,28401094 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27157165 0,28388941 ! camera-type eye development GO:0043010 126 61 0,000 0,27157165 0,28376799 ! proton transport GO:0015992 117 61 0,000 0,27157165 0,28364667 ! viral reproductive process GO:0022415 132 62 0,000 0,27534898 0,28746904 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,27534898 0,28734624 ! tRNA processing GO:0008033 102 62 0,000 0,27534898 0,28722355 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,27534898 0,28710096 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,27910682 0,29089504 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,27910682 0,29077099 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,27910682 0,29064704 ! hydrogen transport GO:0006818 121 64 0,000 0,28284528 0,29441458 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,28284528 0,29428919 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,28656446 0,29803192 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,28656446 0,2979051 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,28656446 0,29777838 ! ear development GO:0043583 114 66 0,000 0,29026446 0,30149493 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29026446 0,30136679 ! gonad development GO:0008406 115 66 0,000 0,29026446 0,30123877 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,29394537 0,30492931 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,29394537 0,30479989 ! secondary metabolic process GO:0019748 125 67 0,000 0,29394537 0,30467057 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,29760729 0,30833529 ! hexose catabolic process GO:0019320 113 68 0,000 0,29760729 0,30820458 ! extracellular matrix organization GO:0030198 146 68 0,000 0,29760729 0,30807399 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,29760729 0,3079435 ! viral reproduction GO:0016032 142 68 0,000 0,29760729 0,30781313 ! adaptive immune response GO:0002250 126 68 0,000 0,29760729 0,30768287 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,29760729 0,30755271 ! cell projection assembly GO:0030031 138 68 0,000 0,29760729 0,30742267 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,30125032 0,31105433 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,30125032 0,31092292 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30125032 0,31079161 ! developmental maturation GO:0021700 128 69 0,000 0,30125032 0,31066042 ! cell redox homeostasis GO:0045454 114 70 0,000 0,30487457 0,31426522 ! germ cell development GO:0007281 133 70 0,000 0,30487457 0,31413267 ! activation of immune response GO:0002253 120 70 0,000 0,30487457 0,31400024 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,30487457 0,31386792 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,30848011 0,31744604 ! carbohydrate transport GO:0008643 114 72 0,000 0,31206705 0,32100203 ! B cell activation GO:0042113 179 72 0,000 0,31206705 0,32086692 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,31206705 0,32073194 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,31206705 0,32059706 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31206705 0,3204623 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31206705 0,32032765 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,31206705 0,32019312 ! humoral immune response GO:0006959 115 73 0,000 0,31563549 0,32371852 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,31563549 0,32358267 ! regulation of immune effector process GO:0002697 156 73 0,000 0,31563549 0,32344694 ! acute inflammatory response GO:0002526 118 74 0,000 0,31918552 0,32694768 ! amino acid transport GO:0006865 148 74 0,000 0,31918552 0,32681066 ! eye development GO:0001654 155 75 0,000 0,32271723 0,33028831 ! rhythmic process GO:0048511 142 75 0,000 0,32271723 0,33015 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,32623073 0,33360471 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,32623073 0,33346513 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,32623073 0,33332566 ! amine catabolic process GO:0009310 136 77 0,000 0,32972609 0,3367562 ! neurotransmitter transport GO:0006836 142 77 0,000 0,32972609 0,33661548 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,32972609 0,33647487 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,32972609 0,33633438 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,32972609 0,336194 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,32972609 0,33605375 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33320342 0,33945619 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,3366628 0,34283753 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,3366628 0,34269468 ! protein oligomerization GO:0051259 149 79 0,000 0,3366628 0,34255195 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,34010434 0,34590962 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,34010434 0,34576567 ! response to hypoxia GO:0001666 178 81 0,000 0,34352811 0,34910116 ! protein import into nucleus GO:0006606 174 82 0,000 0,34693422 0,35241593 ! exocytosis GO:0006887 153 83 0,000 0,35032275 0,35571009 ! response to oxygen levels GO:0070482 183 83 0,000 0,35032275 0,35556231 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35032275 0,35541465 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35032275 0,35526712 ! nuclear import GO:0051170 177 83 0,000 0,35032275 0,3551197 ! inorganic anion transport GO:0015698 156 83 0,000 0,35032275 0,35497241 ! T cell activation GO:0042110 189 84 0,000 0,3536938 0,35823961 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,35704745 0,36148649 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,36370291 0,36807216 ! alcohol catabolic process GO:0046164 142 87 0,000 0,36370291 0,36791975 ! nucleosome assembly GO:0006334 126 87 0,000 0,36370291 0,36776747 ! cellular respiration GO:0045333 143 88 0,000 0,3670049 0,37095282 ! amine biosynthetic process GO:0009309 146 88 0,000 0,3670049 0,37079941 ! sensory perception of smell GO:0007608 117 88 0,000 0,3670049 0,37064612 ! chromatin assembly GO:0031497 128 88 0,000 0,3670049 0,37049296 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,3670049 0,37033993 ! cellular defense response GO:0006968 123 89 0,000 0,37028984 0,37350045 ! protein localization in nucleus GO:0034504 192 89 0,000 0,37028984 0,3733463 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,37355784 0,37648589 ! defense response to bacterium GO:0042742 112 91 0,000 0,37680896 0,37960589 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,3800433 0,38270643 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,38326095 0,3857876 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,38326095 0,38562871 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,38326095 0,38546995 ! vitamin metabolic process GO:0006766 153 93 0,000 0,38326095 0,38531132 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,38646199 0,38836966 ! female pregnancy GO:0007565 166 94 0,000 0,38646199 0,38820997 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,38646199 0,38805041 ! nucleosome organization GO:0034728 143 95 0,000 0,3896465 0,39108727 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,3896465 0,39092665 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,3896465 0,39076618 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,3896465 0,39060583 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,39596629 0,39677837 ! leukocyte differentiation GO:0002521 232 98 0,000 0,39910174 0,39975627 ! forebrain development GO:0030900 210 98 0,000 0,39910174 0,39959244 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,40532416 0,40565625 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,40532416 0,40549014 ! positive regulation of immune response GO:0050778 175 100 0,000 0,40532416 0,40532416