pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6286-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,324E-05 0,024404 ! defense response to bacterium GO:0042742 27 27 2,000 1,033E-04 0,09517409 ! histone modification GO:0016570 28 28 2,000 1,154E-04 0,07090072 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,154E-04 0,05317554 ! mRNA stabilization GO:0048255 5 5 1,000 1,159E-04 0,04271691 GO:0043489|RNA stabilization, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,159E-04 0,03559743 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 1,159E-04 0,03051208 GO:0021517|ventral spinal cord development, ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,159E-04 0,02669807 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,159E-04 0,02373162 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,284E-04 0,02367019 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,284E-04 0,02151835 ! covalent chromatin modification GO:0016569 29 29 2,000 1,284E-04 0,01972516 ! oligosaccharide biosynthetic process GO:0009312 6 6 1,000 1,735E-04 0,02459185 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,735E-04 0,02283529 GO:0018409|peptide or protein amino-terminal blocking, ! cartilage condensation GO:0001502 7 6 1,000 1,735E-04 0,02131293 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,735E-04 0,01998088 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,735E-04 0,01880553 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,735E-04 0,01776078 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 1,735E-04 0,016826 ! regulation of bone resorption GO:0045124 6 6 1,000 1,735E-04 0,0159847 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,735E-04 0,01522352 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,735E-04 0,01453155 ! localization within membrane GO:0051668 6 6 1,000 1,735E-04 0,01389974 ! heart development GO:0007507 90 87 3,000 2,09E-04 0,01604628 ! cell differentiation in spinal cord GO:0021515 7 7 1,000 2,423E-04 0,01786471 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,423E-04 0,01717761 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! regulation of mRNA stability GO:0043488 7 7 1,000 2,423E-04 0,0165414 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,423E-04 0,01595064 ! positive regulation of cell migration GO:0030335 36 36 2,000 2,47E-04 0,01569534 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 2,47E-04 0,01517216 ! lung development GO:0030324 38 37 2,000 2,681E-04 0,01594173 ! cell-matrix adhesion GO:0007160 39 38 2,000 2,905E-04 0,01672893 ! axon guidance GO:0007411 39 38 2,000 2,905E-04 0,01622199 ! respiratory tube development GO:0030323 40 39 2,000 3,14E-04 0,01701794 ! respiratory system development GO:0060541 40 39 2,000 3,14E-04 0,01653171 ! positive regulation of cell motion GO:0051272 39 39 2,000 3,14E-04 0,0160725 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 3,224E-04 0,01606004 ! pancreas development GO:0031016 8 8 1,000 3,224E-04 0,01563741 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 3,224E-04 0,01523645 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 3,224E-04 0,01485554 ! regulation of RNA stability GO:0043487 8 8 1,000 3,224E-04 0,01449321 ! cell-substrate adhesion GO:0031589 43 42 2,000 3,917E-04 0,01718687 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,137E-04 0,01772957 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 1,000 4,137E-04 0,01732663 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 4,137E-04 0,01694159 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 4,137E-04 0,0165733 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 4,137E-04 0,01622067 ! histone acetylation GO:0016573 9 9 1,000 4,137E-04 0,01588274 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 4,137E-04 0,0155586 ! regulation of leukocyte migration GO:0002685 9 9 1,000 4,137E-04 0,01524743 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 4,137E-04 0,01494846 ! homophilic cell adhesion GO:0007156 45 45 2,000 4,808E-04 0,01704122 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 4,808E-04 0,01671968 ! neuromuscular junction development GO:0007528 10 10 1,000 5,16E-04 0,0176099 ! histone deacetylation GO:0016575 10 10 1,000 5,16E-04 0,01728972 ! negative regulation of neuron differentiation GO:0045665 10 10 1,000 5,16E-04 0,01698098 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 5,16E-04 0,01668306 ! ossification GO:0001503 50 49 2,000 6,186E-04 0,01965628 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 2,000 6,186E-04 0,01932312 GO:0060538|skeletal muscle organ development, ! response to bacterium GO:0009617 50 49 2,000 6,186E-04 0,01900107 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 6,186E-04 0,01868958 ! oligosaccharide metabolic process GO:0009311 11 11 1,000 6,293E-04 0,0187061 ! protein amino acid acetylation GO:0006473 11 11 1,000 6,293E-04 0,01840918 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 6,293E-04 0,01812153 GO:0032388|positive regulation of intracellular transport, ! spinal cord development GO:0021510 11 11 1,000 6,293E-04 0,01784274 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 6,293E-04 0,0175724 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 6,293E-04 0,01731012 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 6,293E-04 0,01705556 ! chromatin assembly GO:0031497 50 50 2,000 6,566E-04 0,01753712 GO:0006334|nucleosome assembly, ! protein-DNA complex assembly GO:0065004 51 51 2,000 6,96E-04 0,01832502 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 7,535E-04 0,01956015 ! somitogenesis GO:0001756 13 12 1,000 7,535E-04 0,01928848 ! response to hypoxia GO:0001666 53 53 2,000 7,794E-04 0,01967637 ! response to oxygen levels GO:0070482 55 54 2,000 8,233E-04 0,0205053 ! nucleosome organization GO:0034728 55 55 2,000 8,688E-04 0,02135021 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 8,886E-04 0,02154973 ! vasculogenesis GO:0001570 13 13 1,000 8,886E-04 0,02126987 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 8,886E-04 0,02099718 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 8,886E-04 0,02073139 ! positive regulation of locomotion GO:0040017 13 13 1,000 8,886E-04 0,02047225 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 1,000 8,886E-04 0,0202195 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 8,886E-04 0,01997292 ! neuron fate commitment GO:0048663 14 14 1,000 1,035E-03 0,022972 ! protein amino acid acylation GO:0043543 14 14 1,000 1,035E-03 0,02269852 ! protein amino acid deacetylation GO:0006476 14 14 1,000 1,035E-03 0,02243148 ! regulation of behavior GO:0050795 14 14 1,000 1,035E-03 0,02217065 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,191E-03 0,02523366 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,191E-03 0,02494691 ! protein homooligomerization GO:0051260 15 15 1,000 1,191E-03 0,02466661 ! axonogenesis GO:0007409 66 62 2,000 1,233E-03 0,02524099 ! angiogenesis GO:0001525 65 64 2,000 1,352E-03 0,02737539 ! segmentation GO:0035282 17 16 1,000 1,358E-03 0,02721312 ! DNA packaging GO:0006323 66 66 2,000 1,478E-03 0,02928581 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 1,478E-03 0,02897426 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 1,536E-03 0,02980405 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,536E-03 0,02949359 ! myelination GO:0042552 17 17 1,000 1,536E-03 0,02918953 ! tissue remodeling GO:0048771 17 17 1,000 1,536E-03 0,02889168 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 1,000 1,536E-03 0,02859985 ! neural crest cell development GO:0014032 19 17 1,000 1,536E-03 0,02831385 GO:0014033|neural crest cell differentiation, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,536E-03 0,02803351 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 1,544E-03 0,02788956 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 1,544E-03 0,02761879 ! chromatin assembly or disassembly GO:0006333 68 68 2,000 1,611E-03 0,02855031 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 1,725E-03 0,03027173 ! ensheathment of neurons GO:0007272 18 18 1,000 1,725E-03 0,02998615 GO:0008366|axon ensheathment, ! cell part morphogenesis GO:0032990 75 70 2,000 1,752E-03 0,0301719 ! muscle tissue development GO:0060537 72 70 2,000 1,752E-03 0,02989253 ! regulation of cell migration GO:0030334 71 71 2,000 1,825E-03 0,03085435 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 1,923E-03 0,03222655 ! peripheral nervous system development GO:0007422 19 19 1,000 1,923E-03 0,03193622 ! regulation of cell shape GO:0008360 21 19 1,000 1,923E-03 0,03165108 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 2,304E-03 0,03757227 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,352E-03 0,03802559 ! mammary gland development GO:0030879 23 21 1,000 2,352E-03 0,03769493 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,352E-03 0,03736997 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,352E-03 0,03705057 ! regulation of locomotion GO:0040012 79 79 2,000 2,479E-03 0,03871911 ! regulation of cell motion GO:0051270 79 79 2,000 2,479E-03 0,03839374 ! neuron projection development GO:0031175 85 80 2,000 2,57E-03 0,03946688 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 2,582E-03 0,03932456 GO:0090047|positive regulation of transcription regulator activity, ! neuron migration GO:0001764 22 22 1,000 2,582E-03 0,03900222 ! tube development GO:0035295 83 81 2,000 2,662E-03 0,03989393 ! calcium-mediated signaling GO:0019722 23 23 1,000 2,822E-03 0,04193841 ! blood vessel morphogenesis GO:0048514 84 83 2,000 2,854E-03 0,04208156 ! regulation of action potential GO:0001508 24 24 1,000 3,072E-03 0,0449291 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 3,157E-03 0,04581849 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 3,157E-03 0,04546053 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 3,332E-03 0,0475989 ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,332E-03 0,04723275 ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,332E-03 0,0468722 ! heart morphogenesis GO:0003007 25 25 1,000 3,332E-03 0,0465171 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,332E-03 0,04616735 ! positive regulation of transferase activity GO:0051347 91 88 2,000 3,37E-03 0,04635098 GO:0033674|positive regulation of kinase activity, ! positive regulation of binding GO:0051099 27 26 1,000 3,602E-03 0,04916899 ! regulation of T cell differentiation GO:0045580 26 26 1,000 3,602E-03 0,04880745 ! synapse organization GO:0050808 26 26 1,000 3,602E-03 0,0484512 ! visual perception GO:0007601 93 92 2,000 3,822E-03 0,0510373 GO:0050953|sensory perception of light stimulus, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 3,882E-03 0,05146483 ! mesenchymal cell development GO:0014031 29 27 1,000 3,882E-03 0,05109722 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! blood vessel development GO:0001568 95 94 2,000 4,061E-03 0,05307508 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 4,171E-03 0,05413751 ! cartilage development GO:0051216 29 28 1,000 4,171E-03 0,05375893 ! vasculature development GO:0001944 97 96 2,000 4,308E-03 0,05514266 ! viral reproductive process GO:0022415 29 29 1,000 4,471E-03 0,05682372 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 4,471E-03 0,05643452 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of protein transport GO:0051222 29 29 1,000 4,471E-03 0,05605061 ! response to UV GO:0009411 29 29 1,000 4,471E-03 0,05567189 ! activation of phospholipase C activity GO:0007202 30 30 1,000 4,78E-03 0,05912234 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 4,78E-03 0,05872819 ! skeletal system morphogenesis GO:0048705 31 30 1,000 4,78E-03 0,05833926 ! vascular process in circulatory system GO:0003018 31 30 1,000 4,78E-03 0,05795545 ! muscle organ development GO:0007517 102 100 2,000 4,832E-03 0,05820102 ! response to other organism GO:0051707 101 100 2,000 4,832E-03 0,05782309 ! skeletal muscle fiber development GO:0048741 31 31 1,000 5,099E-03 0,06062434 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 5,099E-03 0,06023572 ! regulation of intracellular transport GO:0032386 31 31 1,000 5,099E-03 0,05985205 ! muscle fiber development GO:0048747 32 32 1,000 5,427E-03 0,06330348 ! regulation of phospholipase activity GO:0010517 32 32 1,000 5,427E-03 0,06290535 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 5,427E-03 0,06251219 ! nuclear export GO:0051168 32 32 1,000 5,427E-03 0,06212391 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 5,427E-03 0,06174043 ! positive regulation of lipase activity GO:0060193 32 32 1,000 5,427E-03 0,06136166 ! regulation of protein complex assembly GO:0043254 33 33 1,000 5,765E-03 0,06478441 ! regulation of neuron differentiation GO:0045664 34 33 1,000 5,765E-03 0,06439177 ! regulation of angiogenesis GO:0045765 35 34 1,000 6,112E-03 0,06785983 ! regulation of bone remodeling GO:0046850 34 34 1,000 6,112E-03 0,06745348 ! viral reproduction GO:0016032 34 34 1,000 6,112E-03 0,06705197 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 6,469E-03 0,07054496 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 6,469E-03 0,07012999 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 6,469E-03 0,06971987 ! regulation of tissue remodeling GO:0034103 35 35 1,000 6,469E-03 0,06931452 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 6,835E-03 0,07281285 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lipase activity GO:0060191 36 36 1,000 6,835E-03 0,07239439 ! regulation of transcription factor activity GO:0051090 38 37 1,000 7,21E-03 0,07593252 GO:0090046|regulation of transcription regulator activity, ! adaptive immune response GO:0002250 37 37 1,000 7,21E-03 0,07550108 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of homeostatic process GO:0032844 38 38 1,000 7,595E-03 0,0790773 ! protein oligomerization GO:0051259 39 39 1,000 7,988E-03 0,08270778 ! regulation of caspase activity GO:0043281 41 41 1,000 8,802E-03 0,09062877 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 9,223E-03 0,09443103 ! forebrain development GO:0030900 43 42 1,000 9,223E-03 0,09390931 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01053735 0,10670511 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01099299 0,11071083 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01099299 0,11010914 ! gland development GO:0048732 51 49 1,000 0,01241144 0,12364474 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01290122 0,12783308 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01290122 0,12714948 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01339939 0,13135683 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 1,000 0,01390589 0,13560085 ! response to light stimulus GO:0009416 53 52 1,000 0,01390589 0,13488716 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,01442066 0,13914803 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01442066 0,1384233 ! regulation of protein transport GO:0051223 53 53 1,000 0,01442066 0,13770608 GO:0070201|regulation of establishment of protein localization, ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01494363 0,14196451 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,01547476 0,14625629 ! extracellular structure organization GO:0043062 56 56 1,000 0,01601397 0,15058037 ! regulation of nervous system development GO:0051960 57 56 1,000 0,01601397 0,149816 ! regulation of binding GO:0051098 60 57 1,000 0,01656122 0,15415321 ! regulation of protein localization GO:0032880 58 57 1,000 0,01656122 0,15337857 ! rRNA transcription GO:0009303 5 5 0,000 0,0173256 0,15965539 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0173256 0,15886109 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0173256 0,15807465 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0173256 0,15729595 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0173256 0,1565249 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0173256 0,15576136 ! reproductive cellular process GO:0048610 5 5 0,000 0,0173256 0,15500524 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,0173256 0,15425642 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0173256 0,1535148 ! prostate gland development GO:0030850 5 5 0,000 0,0173256 0,15278028 ! metencephalon development GO:0022037 5 5 0,000 0,0173256 0,15205276 ! water transport GO:0006833 5 5 0,000 0,0173256 0,15133213 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0173256 0,1506183 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0173256 0,14991117 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0173256 0,14921065 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0173256 0,14851665 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0173256 0,14782907 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0173256 0,14714783 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0173256 0,14647284 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0173256 0,14580401 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0173256 0,14514127 ! filopodium assembly GO:0046847 7 5 0,000 0,0173256 0,14448452 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0173256 0,14383369 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0173256 0,14318869 ! GTP metabolic process GO:0046039 5 5 0,000 0,0173256 0,14254946 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0173256 0,14191591 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0173256 0,14128796 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0173256 0,14066555 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0173256 0,14004859 ! social behavior GO:0035176 5 5 0,000 0,0173256 0,13943703 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0173256 0,13883078 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0173256 0,13822978 ! memory GO:0007613 5 5 0,000 0,0173256 0,13763396 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0173256 0,13704326 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0173256 0,1364576 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0173256 0,13587693 ! response to lipid GO:0033993 5 5 0,000 0,0173256 0,13530118 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0173256 0,13473029 ! hippocampus development GO:0021766 6 5 0,000 0,0173256 0,1341642 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0173256 0,13360284 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0173256 0,13304616 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0173256 0,1324941 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0173256 0,13194661 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0173256 0,13140362 ! heart looping GO:0001947 5 5 0,000 0,0173256 0,13086508 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0173256 0,13033093 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0173256 0,12980113 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0173256 0,12927562 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0173256 0,12875435 ! pH reduction GO:0045851 5 5 0,000 0,0173256 0,12823726 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0173256 0,12772432 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0173256 0,12721545 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0173256 0,12671063 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0173256 0,1262098 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0173256 0,12571291 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0173256 0,12521992 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0173256 0,12473078 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0173256 0,12424544 ! adrenal gland development GO:0030325 5 5 0,000 0,0173256 0,12376387 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0173256 0,12328602 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0173256 0,12281184 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0173256 0,1223413 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0173256 0,12187435 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0173256 0,12141095 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0173256 0,12095106 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0173256 0,12049464 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0173256 0,12004165 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0173256 0,11959206 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0173256 0,11914582 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0173256 0,1187029 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0173256 0,11826325 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0173256 0,11782686 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0173256 0,11739367 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0173256 0,11696366 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0173256 0,11653678 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0173256 0,11611301 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0173256 0,11569231 ! response to ATP GO:0033198 5 5 0,000 0,0173256 0,11527465 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0173256 0,11486 ! regulation of appetite GO:0032098 5 5 0,000 0,0173256 0,11444831 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0173256 0,11403957 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0173256 0,11363373 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0173256 0,11323078 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0173256 0,11283067 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0173256 0,11243338 ! receptor clustering GO:0043113 5 5 0,000 0,0173256 0,11203887 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0173256 0,11164713 ! fear response GO:0042596 5 5 0,000 0,0173256 0,11125811 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0173256 0,1108718 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0173256 0,11048816 ! retinol metabolic process GO:0042572 5 5 0,000 0,0173256 0,11010717 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0173256 0,10972879 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0173256 0,10935301 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0173256 0,10897979 ! parturition GO:0007567 5 5 0,000 0,0173256 0,10860911 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0173256 0,10824095 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0173256 0,10787527 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0173256 0,10751205 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0173256 0,10715127 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0173256 0,10679291 ! protein heterooligomerization GO:0051291 5 5 0,000 0,0173256 0,10643693 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0173256 0,10608332 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0173256 0,10573205 ! response to UV-B GO:0010224 5 5 0,000 0,0173256 0,1053831 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0173256 0,10503644 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0173256 0,10469206 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0173256 0,10434993 ! interaction with symbiont GO:0051702 5 5 0,000 0,0173256 0,10401003 ! cellular extravasation GO:0045123 5 5 0,000 0,0173256 0,10367233 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0173256 0,10333682 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0173256 0,10300348 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0173256 0,10267228 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0173256 0,1023432 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0173256 0,10201623 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0173256 0,10169133 ! response to amine stimulus GO:0014075 5 5 0,000 0,0173256 0,1013685 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0173256 0,10104772 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0173256 0,10072896 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0173256 0,1004122 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0173256 0,10009743 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0173256 0,09978462 ! neuron recognition GO:0008038 5 5 0,000 0,0173256 0,09947377 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,0173256 0,09916484 ! decidualization GO:0046697 5 5 0,000 0,0173256 0,09885783 ! hair follicle maturation GO:0048820 5 5 0,000 0,0173256 0,09855271 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0173256 0,09824947 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0173256 0,09794809 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0173256 0,09764856 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0173256 0,09735085 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0173256 0,09705495 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0173256 0,09676084 ! postreplication repair GO:0006301 5 5 0,000 0,0173256 0,09646852 ! cellular pigmentation GO:0033059 5 5 0,000 0,0173256 0,09617795 ! histone methylation GO:0016571 5 5 0,000 0,0173256 0,09588913 ! DNA methylation GO:0006306 5 5 0,000 0,0173256 0,09560203 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0173256 0,09531665 ! T cell lineage commitment GO:0002360 5 5 0,000 0,0173256 0,09503297 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0173256 0,09475098 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0173256 0,09447065 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0173256 0,09419197 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0173256 0,09391494 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0173256 0,09363953 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0173256 0,09336573 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0173256 0,09309352 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0173256 0,0928229 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0173256 0,09255385 ! sterol catabolic process GO:0016127 5 5 0,000 0,0173256 0,09228635 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0173256 0,0920204 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0173256 0,09175597 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0173256 0,09149306 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0173256 0,09123165 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0173256 0,09097173 ! zymogen activation GO:0031638 5 5 0,000 0,0173256 0,09071329 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0173256 0,09045631 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0173256 0,09020079 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0173256 0,0899467 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,0173256 0,08969404 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0173256 0,0894428 ! nucleosome positioning GO:0016584 5 5 0,000 0,0173256 0,08919296 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0173256 0,08894451 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0173256 0,08869744 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0173256 0,08845174 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0173256 0,0882074 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0173256 0,0879644 ! NADPH regeneration GO:0006740 5 5 0,000 0,0173256 0,08772274 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0173256 0,08748241 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0173256 0,08724338 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0173256 0,08700566 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0173256 0,08676924 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0173256 0,08653409 ! sarcomere organization GO:0045214 5 5 0,000 0,0173256 0,08630021 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0173256 0,0860676 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0173256 0,08583623 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0173256 0,08560611 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0173256 0,08537722 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0173256 0,08514954 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0173256 0,08492308 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0173256 0,08469782 ! spleen development GO:0048536 5 5 0,000 0,0173256 0,08447375 ! male genitalia development GO:0030539 5 5 0,000 0,0173256 0,08425087 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0173256 0,08402915 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0173256 0,08380861 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0173256 0,08358921 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0173256 0,08337096 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0173256 0,08315385 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0173256 0,08293787 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0173256 0,082723 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0173256 0,08250925 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0173256 0,08229659 ! ATP catabolic process GO:0006200 5 5 0,000 0,0173256 0,08208504 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0173256 0,08187456 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0173256 0,08166516 ! blastocyst formation GO:0001825 5 5 0,000 0,0173256 0,08145683 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0173256 0,08124956 ! embryonic gut development GO:0048566 5 5 0,000 0,0173256 0,08104335 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0173256 0,08083817 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0173256 0,08063404 ! activation of innate immune response GO:0002218 5 5 0,000 0,0173256 0,08043093 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,0173256 0,08022884 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0173256 0,08002777 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0173256 0,0798277 ! muscle adaptation GO:0043500 5 5 0,000 0,0173256 0,07962863 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0173256 0,07943054 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0173256 0,07923345 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0173256 0,07903732 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0173256 0,07884217 ! defense response to fungus GO:0050832 5 5 0,000 0,0173256 0,07864798 ! lysogeny GO:0030069 5 5 0,000 0,0173256 0,07845474 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0173256 0,07826245 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0173256 0,0780711 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0173256 0,07788068 ! response to nicotine GO:0035094 5 5 0,000 0,0173256 0,07769119 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0173256 0,07750262 ! mitochondrion localization GO:0051646 5 5 0,000 0,0173256 0,07731496 ! nucleus localization GO:0051647 5 5 0,000 0,0173256 0,07712821 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0173256 0,07694236 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,0176796 0,07832571 ! regulation of cell development GO:0060284 60 59 1,000 0,0176796 0,07813788 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,01882941 0,0830206 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,01941597 0,08540248 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,01941597 0,08519915 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02061212 0,09023308 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02075603 0,09064776 ! axon extension GO:0048675 7 6 0,000 0,02075603 0,09043347 ! tRNA modification GO:0006400 6 6 0,000 0,02075603 0,09022018 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02075603 0,0900079 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02075603 0,08979661 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02075603 0,08958631 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02075603 0,089377 ! virus-host interaction GO:0019048 6 6 0,000 0,02075603 0,08916866 ! regulation of S phase GO:0033261 6 6 0,000 0,02075603 0,08896129 ! myotube differentiation GO:0014902 6 6 0,000 0,02075603 0,08875489 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02075603 0,08854943 ! bone remodeling GO:0046849 6 6 0,000 0,02075603 0,08834493 ! N-glycan processing GO:0006491 6 6 0,000 0,02075603 0,08814137 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02075603 0,08793875 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02075603 0,08773705 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02075603 0,08753628 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02075603 0,08733643 ! RNA methylation GO:0001510 6 6 0,000 0,02075603 0,08713748 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02075603 0,08693944 ! succinate metabolic process GO:0006105 7 6 0,000 0,02075603 0,0867423 ! artery development GO:0060840 6 6 0,000 0,02075603 0,08654605 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02075603 0,08635069 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02075603 0,08615621 ! androgen metabolic process GO:0008209 6 6 0,000 0,02075603 0,0859626 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02075603 0,08576986 ! limbic system development GO:0021761 7 6 0,000 0,02075603 0,08557798 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02075603 0,08538695 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02075603 0,08519678 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02075603 0,08500746 ! pathogenesis GO:0009405 6 6 0,000 0,02075603 0,08481897 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02075603 0,08463132 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02075603 0,08444449 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02075603 0,08425849 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02075603 0,08407331 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02075603 0,08388894 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02075603 0,08370537 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02075603 0,08352261 ! arginine metabolic process GO:0006525 6 6 0,000 0,02075603 0,08334064 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02075603 0,08315947 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02075603 0,08297908 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02075603 0,08279947 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02075603 0,08262064 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02075603 0,08244258 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02075603 0,08226528 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02075603 0,08208875 ! ER overload response GO:0006983 6 6 0,000 0,02075603 0,08191297 ! V(D)J recombination GO:0033151 6 6 0,000 0,02075603 0,08173794 ! focal adhesion formation GO:0048041 7 6 0,000 0,02075603 0,08156366 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02075603 0,08139012 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02075603 0,08121732 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02075603 0,08104525 ! regulation of heart rate GO:0002027 6 6 0,000 0,02075603 0,0808739 ! lipid digestion GO:0044241 6 6 0,000 0,02075603 0,08070328 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02075603 0,08053338 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02075603 0,08036419 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02075603 0,08019571 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02075603 0,08002794 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02075603 0,07986087 ! ruffle organization GO:0031529 6 6 0,000 0,02075603 0,07969449 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02075603 0,07952881 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02075603 0,07936381 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02075603 0,07919949 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02075603 0,07903586 ! L-amino acid transport GO:0015807 6 6 0,000 0,02075603 0,0788729 ! bone mineralization GO:0030282 6 6 0,000 0,02075603 0,07871061 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02075603 0,07854899 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02075603 0,07838802 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02075603 0,07822772 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02075603 0,07806807 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02075603 0,07790907 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02075603 0,07775072 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02075603 0,07759301 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02075603 0,07743594 ! regulation of organ growth GO:0046620 6 6 0,000 0,02075603 0,07727951 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02075603 0,0771237 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02075603 0,07696852 ! response to dsRNA GO:0043331 6 6 0,000 0,02075603 0,07681397 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02075603 0,07666003 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02075603 0,07650671 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02075603 0,076354 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02075603 0,0762019 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02075603 0,07605041 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02075603 0,07589952 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02075603 0,07574922 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02075603 0,07559952 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02075603 0,07545041 ! erythrocyte development GO:0048821 6 6 0,000 0,02075603 0,07530188 ! renal water homeostasis GO:0003091 6 6 0,000 0,02075603 0,07515394 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02075603 0,07500658 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02075603 0,0748598 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02075603 0,07471359 ! ribosome assembly GO:0042255 6 6 0,000 0,02075603 0,07456794 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02075603 0,07442287 ! diencephalon development GO:0021536 6 6 0,000 0,02075603 0,07427836 ! fucose catabolic process GO:0019317 6 6 0,000 0,02075603 0,07413441 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02075603 0,07399102 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02075603 0,07384818 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02075603 0,07370589 ! regulation of cell division GO:0051302 6 6 0,000 0,02075603 0,07356415 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02075603 0,07342295 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02075603 0,07328229 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02075603 0,07314217 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02075603 0,07300259 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02075603 0,07286353 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02075603 0,07272501 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02075603 0,07258701 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02075603 0,07244954 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02075603 0,07231258 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02075603 0,07217614 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02075603 0,07204022 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02075603 0,0719048 ! thymus development GO:0048538 6 6 0,000 0,02075603 0,0717699 ! lymph node development GO:0048535 6 6 0,000 0,02075603 0,0716355 ! organic cation transport GO:0015695 6 6 0,000 0,02075603 0,0715016 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02075603 0,0713682 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02075603 0,0712353 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02075603 0,07110289 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02075603 0,07097098 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02075603 0,07083955 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02075603 0,07070861 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02075603 0,07057815 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02075603 0,07044817 ! alditol metabolic process GO:0019400 6 6 0,000 0,02075603 0,07031867 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02075603 0,07018964 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02075603 0,07006109 ! maternal placenta development GO:0001893 6 6 0,000 0,02075603 0,06993301 ! regulation of embryonic development GO:0045995 6 6 0,000 0,02075603 0,06980539 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02075603 0,06967824 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,02246304 0,07527161 ! response to radiation GO:0009314 70 68 1,000 0,02309492 0,07724852 ! sensory perception of sound GO:0007605 71 69 1,000 0,02373415 0,07924284 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,02373415 0,07909954 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02373415 0,07895676 ! respiratory burst GO:0045730 7 7 0,000 0,02417497 0,08027834 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02417497 0,08013395 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02417497 0,07999009 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02417497 0,07984674 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02417497 0,0797039 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02417497 0,07956157 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02417497 0,07941975 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02417497 0,07927843 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02417497 0,07913762 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02417497 0,0789973 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02417497 0,07885748 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02417497 0,07871816 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02417497 0,07857933 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02417497 0,07844098 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02417497 0,07830313 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02417497 0,07816575 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02417497 0,07802886 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02417497 0,07789245 ! axis specification GO:0009798 7 7 0,000 0,02417497 0,07775651 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02417497 0,07762104 ! visual behavior GO:0007632 7 7 0,000 0,02417497 0,07748605 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02417497 0,07735153 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02417497 0,07721747 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02417497 0,07708387 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02417497 0,07695074 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02417497 0,07681807 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02417497 0,07668585 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02417497 0,07655409 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02417497 0,07642278 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02417497 0,07629192 ! digestive system development GO:0055123 7 7 0,000 0,02417497 0,0761615 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02417497 0,07603153 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02417497 0,07590201 ! protein targeting to ER GO:0045047 8 7 0,000 0,02417497 0,07577292 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02417497 0,07564428 ! endoderm development GO:0007492 7 7 0,000 0,02417497 0,07551607 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02417497 0,07538829 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02417497 0,07526094 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02417497 0,07513403 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02417497 0,07500754 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02417497 0,07488148 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02417497 0,07475584 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02417497 0,07463062 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02417497 0,07450582 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02417497 0,07438143 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02417497 0,07425746 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02417497 0,07413391 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02417497 0,07401076 ! response to X-ray GO:0010165 7 7 0,000 0,02417497 0,07388802 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,02417497 0,07376569 ! UV protection GO:0009650 7 7 0,000 0,02417497 0,07364377 ! DNA integration GO:0015074 7 7 0,000 0,02417497 0,07352224 ! myofibril assembly GO:0030239 7 7 0,000 0,02417497 0,07340112 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02417497 0,07328039 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02417497 0,07316006 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02417497 0,07304013 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02417497 0,07292059 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02417497 0,07280144 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02417497 0,07268267 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02417497 0,0725643 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02417497 0,07244631 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02417497 0,0723287 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02417497 0,07221147 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02417497 0,07209463 ! axon cargo transport GO:0008088 7 7 0,000 0,02417497 0,07197816 ! eating behavior GO:0042755 7 7 0,000 0,02417497 0,07186206 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02417497 0,07174634 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02417497 0,07163099 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02417497 0,07151602 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02417497 0,07140141 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02417497 0,07128717 ! cranial nerve development GO:0021545 7 7 0,000 0,02417497 0,07117329 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02417497 0,07105977 ! induction of an organ GO:0001759 7 7 0,000 0,02417497 0,07094662 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02417497 0,07083383 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02417497 0,07072139 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02417497 0,07060932 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02417497 0,07049759 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02417497 0,07038622 ! platelet activation GO:0030168 8 7 0,000 0,02417497 0,0702752 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02417497 0,07016453 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02417497 0,07005421 ! natural killer cell activation GO:0030101 7 7 0,000 0,02417497 0,06994424 ! response to gamma radiation GO:0010332 8 7 0,000 0,02417497 0,06983461 ! NADP metabolic process GO:0006739 7 7 0,000 0,02417497 0,06972532 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02417497 0,06961637 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02417497 0,06950777 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02417497 0,0693995 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02417497 0,06929157 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02417497 0,06918397 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02417497 0,06907671 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02417497 0,06896978 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02417497 0,06886318 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02417497 0,06875691 ! cell-cell recognition GO:0009988 8 7 0,000 0,02417497 0,06865097 ! hormone catabolic process GO:0042447 7 7 0,000 0,02417497 0,06854535 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02417497 0,06844006 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02417497 0,06833509 ! oxygen transport GO:0015671 7 7 0,000 0,02417497 0,06823044 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02417497 0,06812611 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02417497 0,0680221 ! regulation of axon extension GO:0030516 7 7 0,000 0,02417497 0,06791841 ! cell killing GO:0001906 7 7 0,000 0,02417497 0,06781504 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02417497 0,06771197 ! adult feeding behavior GO:0008343 7 7 0,000 0,02417497 0,06760922 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02417497 0,06750679 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02417497 0,06740466 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02417497 0,06730284 ! response to cold GO:0009409 7 7 0,000 0,02417497 0,06720133 ! positive regulation of transport GO:0051050 71 70 1,000 0,0243807 0,06767112 ! wound healing GO:0042060 74 70 1,000 0,0243807 0,06756936 ! regulation of cell activation GO:0050865 71 71 1,000 0,02503449 0,06927713 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,02569548 0,07099966 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02758248 0,07609957 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02758248 0,07598582 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02758248 0,07587241 ! positive regulation of translation GO:0045727 8 8 0,000 0,02758248 0,07575934 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02758248 0,0756466 ! superoxide anion generation GO:0042554 8 8 0,000 0,02758248 0,0755342 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02758248 0,07542213 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02758248 0,07531039 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02758248 0,07519899 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02758248 0,07508791 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02758248 0,07497716 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02758248 0,07486674 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02758248 0,07475664 ! zinc ion transport GO:0006829 8 8 0,000 0,02758248 0,07464687 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02758248 0,07453741 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02758248 0,07442828 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02758248 0,07431947 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02758248 0,07421097 ! lipid localization GO:0010876 8 8 0,000 0,02758248 0,07410279 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02758248 0,07399493 ! response to cAMP GO:0051591 8 8 0,000 0,02758248 0,07388738 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02758248 0,07378014 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02758248 0,07367321 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02758248 0,07356659 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02758248 0,07346028 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02758248 0,07335428 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02758248 0,07324858 ! sensory perception of taste GO:0050909 8 8 0,000 0,02758248 0,07314319 ! organelle fusion GO:0048284 8 8 0,000 0,02758248 0,0730381 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02758248 0,07293331 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02758248 0,07282882 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02758248 0,07272463 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02758248 0,07262074 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02758248 0,07251714 ! sperm motility GO:0030317 8 8 0,000 0,02758248 0,07241384 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02758248 0,07231083 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02758248 0,07220812 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02758248 0,0721057 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02758248 0,07200356 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02758248 0,07190172 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02758248 0,07180016 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02758248 0,07169889 ! Golgi organization GO:0007030 8 8 0,000 0,02758248 0,07159791 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02758248 0,07149721 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02758248 0,07139679 ! fructose metabolic process GO:0006000 8 8 0,000 0,02758248 0,07129666 ! mannose metabolic process GO:0006013 9 8 0,000 0,02758248 0,0711968 ! NAD metabolic process GO:0019674 8 8 0,000 0,02758248 0,07109722 ! sex determination GO:0007530 8 8 0,000 0,02758248 0,07099793 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02758248 0,07089891 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02758248 0,07080016 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,02758248 0,07070169 ! response to fungus GO:0009620 8 8 0,000 0,02758248 0,07060349 ! stem cell differentiation GO:0048863 8 8 0,000 0,02758248 0,07050557 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02758248 0,07040792 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02758248 0,07031053 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02758248 0,07021342 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02758248 0,07011657 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02758248 0,07001999 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02758248 0,06992368 ! vasoconstriction GO:0042310 8 8 0,000 0,02758248 0,06982763 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02758248 0,06973185 ! muscle cell development GO:0055001 8 8 0,000 0,02758248 0,06963632 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02758248 0,06954106 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02758248 0,06944606 ! sensory perception of pain GO:0019233 8 8 0,000 0,02758248 0,06935132 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02758248 0,06925683 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02758248 0,06916261 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02758248 0,06906864 ! chromatin silencing GO:0006342 8 8 0,000 0,02758248 0,06897492 ! tissue regeneration GO:0042246 8 8 0,000 0,02758248 0,06888146 ! salivary gland development GO:0007431 8 8 0,000 0,02758248 0,06878825 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02758248 0,06869529 ! T cell homeostasis GO:0043029 8 8 0,000 0,02758248 0,06860259 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02758248 0,06851013 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02758248 0,06841792 ! water homeostasis GO:0030104 8 8 0,000 0,02758248 0,06832596 ! cofactor transport GO:0051181 8 8 0,000 0,02758248 0,06823425 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02758248 0,06814278 ! acid secretion GO:0046717 8 8 0,000 0,02758248 0,06805156 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02758248 0,06796058 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02758248 0,06786985 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02758248 0,06777935 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02758248 0,0676891 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02758248 0,06759909 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02758248 0,06750932 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,02758248 0,06741978 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02758248 0,06733048 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,02758248 0,06724142 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02758248 0,0671526 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02758248 0,067064 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02758248 0,06697565 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02758248 0,06688752 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02758248 0,06679963 ! developmental induction GO:0031128 8 8 0,000 0,02758248 0,06671196 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02758248 0,06662453 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02758248 0,06653732 ! actin filament polymerization GO:0030041 9 8 0,000 0,02758248 0,06645035 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02758248 0,0663636 ! peptide hormone processing GO:0016486 8 8 0,000 0,02758248 0,06627707 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02758248 0,06619078 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02758248 0,0661047 ! regulation of protein modification process GO:0031399 79 78 1,000 0,02980959 0,07134944 ! nuclear transport GO:0051169 79 79 1,000 0,03051947 0,07295381 GO:0006913|nucleocytoplasmic transport, ! lactation GO:0007595 10 9 0,000 0,03097859 0,07395535 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03097859 0,07385968 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03097859 0,07376426 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03097859 0,07366908 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03097859 0,07357414 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03097859 0,07347945 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03097859 0,073385 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03097859 0,0732908 ! viral genome replication GO:0019079 9 9 0,000 0,03097859 0,07319684 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03097859 0,07310312 ! copper ion transport GO:0006825 9 9 0,000 0,03097859 0,07300963 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03097859 0,07291639 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03097859 0,07282338 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03097859 0,07273062 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03097859 0,07263808 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03097859 0,07254579 GO:0006378|mRNA polyadenylation, ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03097859 0,07245372 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03097859 0,07236189 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03097859 0,0722703 ! phospholipid efflux GO:0033700 9 9 0,000 0,03097859 0,07217893 ! response to alkaloid GO:0043279 10 9 0,000 0,03097859 0,07208779 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03097859 0,07199689 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03097859 0,07190621 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03097859 0,07181577 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03097859 0,07172554 ! response to ethanol GO:0045471 9 9 0,000 0,03097859 0,07163555 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03097859 0,07154578 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03097859 0,07145624 ! methionine metabolic process GO:0006555 9 9 0,000 0,03097859 0,07136692 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03097859 0,07127782 ! cerebral cortex development GO:0021987 9 9 0,000 0,03097859 0,07118894 ! response to osmotic stress GO:0006970 9 9 0,000 0,03097859 0,07110029 ! pigmentation during development GO:0048066 9 9 0,000 0,03097859 0,07101186 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03097859 0,07092364 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03097859 0,07083565 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03097859 0,07074787 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03097859 0,07066031 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03097859 0,07057297 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03097859 0,07048584 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03097859 0,07039893 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03097859 0,07031223 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03097859 0,07022575 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03097859 0,07013948 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03097859 0,07005342 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03097859 0,06996757 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03097859 0,06988193 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03097859 0,0697965 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03097859 0,06971127 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03097859 0,06962626 ! DNA replication initiation GO:0006270 9 9 0,000 0,03097859 0,06954145 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03097859 0,06945685 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03097859 0,06937246 ! regulation of cellular pH GO:0030641 9 9 0,000 0,03097859 0,06928827 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03097859 0,06920428 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03097859 0,0691205 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03097859 0,06903692 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03097859 0,06895354 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03097859 0,06887037 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03097859 0,06878739 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03097859 0,06870461 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03097859 0,06862204 ! collagen catabolic process GO:0030574 9 9 0,000 0,03097859 0,06853966 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03097859 0,06845747 ! purine base metabolic process GO:0006144 9 9 0,000 0,03097859 0,06837549 ! gas transport GO:0015669 9 9 0,000 0,03097859 0,0682937 ! cholesterol efflux GO:0033344 9 9 0,000 0,03097859 0,06821211 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03097859 0,06813071 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03097859 0,0680495 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03097859 0,06796849 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03097859 0,06788767 ! defense response to virus GO:0051607 9 9 0,000 0,03097859 0,06780705 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03097859 0,06772661 ! actin filament-based movement GO:0030048 9 9 0,000 0,03097859 0,06764637 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03097859 0,06756631 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03436332 0,07486005 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03436332 0,07477166 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03436332 0,07468349 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03436332 0,07459552 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,03436332 0,07450776 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03436332 0,07442021 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03436332 0,07433286 ! neuron maturation GO:0042551 10 10 0,000 0,03436332 0,07424572 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03436332 0,07415878 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03436332 0,07407205 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03436332 0,07398551 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03436332 0,07389918 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03436332 0,07381305 ! hormone secretion GO:0046879 10 10 0,000 0,03436332 0,07372712 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03436332 0,0736414 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03436332 0,07355587 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03436332 0,07347053 ! inositol metabolic process GO:0006020 10 10 0,000 0,03436332 0,0733854 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03436332 0,07330046 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03436332 0,07321572 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03436332 0,07313118 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03436332 0,07304683 ! glial cell development GO:0021782 10 10 0,000 0,03436332 0,07296267 ! phototransduction GO:0007602 11 10 0,000 0,03436332 0,07287871 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03436332 0,07279494 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03436332 0,07271137 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,03436332 0,07262798 ! fat cell differentiation GO:0045444 10 10 0,000 0,03436332 0,07254479 ! myoblast differentiation GO:0045445 10 10 0,000 0,03436332 0,07246178 ! centrosome cycle GO:0007098 10 10 0,000 0,03436332 0,07237897 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03436332 0,07229635 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03436332 0,07221391 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03436332 0,07213166 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03436332 0,0720496 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03436332 0,07196773 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03436332 0,07188604 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03436332 0,07180454 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03436332 0,07172322 ! plasma membrane organization GO:0007009 10 10 0,000 0,03436332 0,07164208 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03436332 0,07156113 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03436332 0,07148036 ! lysosomal transport GO:0007041 10 10 0,000 0,03436332 0,07139977 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03436332 0,07131937 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03436332 0,07123915 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03436332 0,0711591 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03436332 0,07107924 ! exocrine system development GO:0035272 10 10 0,000 0,03436332 0,07099955 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03436332 0,07092004 ! embryo implantation GO:0007566 11 10 0,000 0,03436332 0,07084072 ! regulation of protein binding GO:0043393 11 10 0,000 0,03436332 0,07076156 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03436332 0,07068259 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03436332 0,07060379 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03436332 0,07052517 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03436332 0,07044672 ! protein export from nucleus GO:0006611 10 10 0,000 0,03436332 0,07036844 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03436332 0,07029034 ! cytolysis GO:0019835 10 10 0,000 0,03436332 0,07021242 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03436332 0,07013466 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03436332 0,07005708 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03436332 0,06997967 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03436332 0,06990243 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03436332 0,06982536 ! gland morphogenesis GO:0022612 10 10 0,000 0,03436332 0,06974846 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03436332 0,06967173 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03436332 0,06959516 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03436332 0,06951877 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03436332 0,06944254 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03436332 0,06936648 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03436332 0,06929059 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03436332 0,06921486 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03436332 0,0691393 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03436332 0,0690639 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03436332 0,06898867 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03436332 0,0689136 ! nerve development GO:0021675 10 10 0,000 0,03436332 0,0688387 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03436332 0,06876395 ! gut development GO:0048565 10 10 0,000 0,03436332 0,06868937 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03436332 0,06861495 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,03436332 0,06854069 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03436332 0,06846659 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03436332 0,06839266 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03436332 0,06831888 ! protein stabilization GO:0050821 10 10 0,000 0,03436332 0,06824526 ! regulation of cellular localization GO:0060341 86 85 1,000 0,03491926 0,0692747 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,03491926 0,06920021 ! protein secretion GO:0009306 11 11 0,000 0,03773672 0,07470331 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,03773672 0,07462316 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03773672 0,07454317 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03773672 0,07446336 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03773672 0,07438372 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03773672 0,07430425 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,03773672 0,07422495 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03773672 0,07414582 ! skin development GO:0043588 11 11 0,000 0,03773672 0,07406686 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03773672 0,07398807 ! signal complex assembly GO:0007172 11 11 0,000 0,03773672 0,07390944 ! microtubule-based transport GO:0010970 11 11 0,000 0,03773672 0,07383098 ! endothelial cell migration GO:0043542 11 11 0,000 0,03773672 0,07375269 ! peroxisomal transport GO:0043574 11 11 0,000 0,03773672 0,07367456 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03773672 0,07359659 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,03773672 0,0735188 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03773672 0,07344116 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03773672 0,07336369 ! T cell proliferation GO:0042098 11 11 0,000 0,03773672 0,07328639 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03773672 0,07320924 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03773672 0,07313226 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03773672 0,07305544 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,03773672 0,07297879 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03773672 0,07290229 ! cellular response to starvation GO:0009267 11 11 0,000 0,03773672 0,07282595 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03773672 0,07274977 ! digestive system process GO:0022600 11 11 0,000 0,03773672 0,07267375 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03773672 0,07259789 ! fucose metabolic process GO:0006004 11 11 0,000 0,03773672 0,07252219 ! membrane budding GO:0006900 11 11 0,000 0,03773672 0,07244665 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03773672 0,07237126 ! monoamine transport GO:0015844 11 11 0,000 0,03773672 0,07229603 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03773672 0,07222096 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03773672 0,07214604 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,03773672 0,07207128 ! body fluid secretion GO:0007589 11 11 0,000 0,03773672 0,07199667 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,03773672 0,07192222 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03773672 0,07184792 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03773672 0,07177377 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03773672 0,07169978 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,03773672 0,07162593 ! membrane depolarization GO:0051899 11 11 0,000 0,03773672 0,07155225 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03773672 0,07147871 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03773672 0,07140532 ! oogenesis GO:0048477 11 11 0,000 0,03773672 0,07133208 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03773672 0,071259 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03773672 0,07118606 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,03773672 0,07111327 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,03773672 0,07104064 ! muscle maintenance GO:0046716 12 11 0,000 0,03773672 0,07096815 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03773672 0,0708958 ! hindbrain development GO:0030902 11 11 0,000 0,03773672 0,07082361 ! steroid catabolic process GO:0006706 11 11 0,000 0,03773672 0,07075156 ! endocrine process GO:0050886 11 11 0,000 0,03773672 0,07067966 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03773672 0,0706079 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03773672 0,07053629 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03773672 0,07046482 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03773672 0,0703935 ! brain development GO:0007420 91 90 1,000 0,03876414 0,07223692 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,03955198 0,0736306 ! DNA replication GO:0006260 91 91 1,000 0,03955198 0,0735563 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,04034599 0,07495731 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04109883 0,0762791 ! translational initiation GO:0006413 12 12 0,000 0,04109883 0,07620236 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04109883 0,07612578 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04109883 0,07604934 ! initiation of viral infection GO:0019059 12 12 0,000 0,04109883 0,07597307 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04109883 0,07589694 ! iron ion transport GO:0006826 13 12 0,000 0,04109883 0,07582097 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04109883 0,07574515 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04109883 0,07566948 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04109883 0,07559396 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04109883 0,07551859 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04109883 0,07544337 ! collagen metabolic process GO:0032963 12 12 0,000 0,04109883 0,07536831 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04109883 0,07529339 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04109883 0,07521862 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04109883 0,07514399 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04109883 0,07506952 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04109883 0,07499519 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04109883 0,07492102 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04109883 0,07484698 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04109883 0,0747731 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04109883 0,07469936 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04109883 0,07462576 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04109883 0,07455231 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04109883 0,074479 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04109883 0,07440584 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04109883 0,07433282 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04109883 0,07425995 ! acute-phase response GO:0006953 12 12 0,000 0,04109883 0,07418722 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04109883 0,07411463 ! vacuolar transport GO:0007034 12 12 0,000 0,04109883 0,07404218 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04109883 0,07396987 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04109883 0,0738977 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04109883 0,07382568 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04109883 0,07375379 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04109883 0,07368205 ! male gonad development GO:0008584 12 12 0,000 0,04109883 0,07361044 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04109883 0,07353898 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04109883 0,07346765 ! renal system process GO:0003014 12 12 0,000 0,04109883 0,07339646 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04109883 0,07332541 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04109883 0,07325449 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04109883 0,07318372 ! pallium development GO:0021543 13 12 0,000 0,04109883 0,07311308 ! cell fate determination GO:0001709 12 12 0,000 0,04109883 0,07304257 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04109883 0,0729722 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04109883 0,07290197 ! G1 phase GO:0051318 13 12 0,000 0,04109883 0,07283187 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04109883 0,07276191 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04109883 0,07269208 ! detection of light stimulus GO:0009583 13 12 0,000 0,04109883 0,07262238 ! synaptogenesis GO:0007416 12 12 0,000 0,04109883 0,07255282 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04109883 0,07248339 ! hormone transport GO:0009914 12 12 0,000 0,04109883 0,0724141 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04109883 0,07234493 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04109883 0,0722759 ! spermatid differentiation GO:0048515 13 12 0,000 0,04109883 0,072207 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04109883 0,07213824 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04109883 0,0720696 ! neural tube closure GO:0001843 13 12 0,000 0,04109883 0,07200109 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04109883 0,07193271 ! negative regulation of translation GO:0017148 12 12 0,000 0,04109883 0,07186447 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04109883 0,07179635 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,04109883 0,07172836 ! pattern specification process GO:0007389 96 94 1,000 0,04195233 0,07314867 ! epidermis development GO:0008544 94 94 1,000 0,04195233 0,07307953 ! regulation of cell growth GO:0001558 97 96 1,000 0,04358278 0,07584802 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,04444968 0,07728374 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04444968 0,0772109 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04444968 0,07713819 ! phenol metabolic process GO:0018958 13 13 0,000 0,04444968 0,07706563 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04444968 0,0769932 ! gluconeogenesis GO:0006094 13 13 0,000 0,04444968 0,0769209 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04444968 0,07684874 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04444968 0,07677672 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04444968 0,07670483 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04444968 0,07663308 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04444968 0,07656146 ! regeneration GO:0031099 13 13 0,000 0,04444968 0,07648997 ! keratinization GO:0031424 13 13 0,000 0,04444968 0,07641862 ! post-embryonic development GO:0009791 14 13 0,000 0,04444968 0,0763474 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04444968 0,07627631 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04444968 0,07620536 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04444968 0,07613454 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04444968 0,07606384 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,04444968 0,07599328 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,04444968 0,07592286 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04444968 0,07585256 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04444968 0,07578239 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04444968 0,07571235 ! autophagy GO:0006914 13 13 0,000 0,04444968 0,07564244 ! receptor metabolic process GO:0043112 14 13 0,000 0,04444968 0,07557266 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04444968 0,07550301 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04444968 0,07543348 ! ureteric bud development GO:0001657 13 13 0,000 0,04444968 0,07536409 ! cell aging GO:0007569 13 13 0,000 0,04444968 0,07529482 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,04444968 0,07522568 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,04444968 0,07515666 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04444968 0,07508777 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04444968 0,07501901 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04444968 0,07495038 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04444968 0,07488187 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04444968 0,07481348 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04444968 0,07474522 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04444968 0,07467708 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04444968 0,07460907 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04444968 0,07454118 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04444968 0,07447342 ! vasodilation GO:0042311 14 13 0,000 0,04444968 0,07440578 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04444968 0,07433826 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04444968 0,07427086 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04444968 0,07420359 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04444968 0,07413644 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04444968 0,0740694 ! immunoglobulin production GO:0002377 13 13 0,000 0,04444968 0,07400249 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04444968 0,0739357 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04444968 0,07386904 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04444968 0,07380249 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04444968 0,07373606 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04444968 0,07366975 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04444968 0,07360356 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04444968 0,07353749 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04444968 0,07347153 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04444968 0,0734057 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04444968 0,07333998 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04444968 0,07327438 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04444968 0,0732089 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04444968 0,07314354 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04444968 0,07307829 ! blastocyst development GO:0001824 13 13 0,000 0,04444968 0,07301316 ! telomere organization GO:0032200 13 13 0,000 0,04444968 0,07294814 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04444968 0,07288324 ! regulation of amine transport GO:0051952 13 13 0,000 0,04444968 0,07281845 ! tissue homeostasis GO:0001894 13 13 0,000 0,04444968 0,07275378 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04444968 0,07268923 ! protein tetramerization GO:0051262 13 13 0,000 0,04444968 0,07262479 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,04523695 0,07384562 ! blood circulation GO:0008015 99 98 1,000 0,04523695 0,07378027 GO:0003013|circulatory system process, ! ectoderm development GO:0007398 99 99 1,000 0,04607282 0,0750771 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,04691448 0,07638108 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04778931 0,07773671 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04778931 0,07766816 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,04778931 0,07759973 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04778931 0,07753142 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,04778931 0,07746323 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,04778931 0,07739516 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04778931 0,07732721 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04778931 0,07725938 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04778931 0,07719167 ! vesicle docking GO:0048278 14 14 0,000 0,04778931 0,07712407 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04778931 0,0770566 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04778931 0,07698924 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,04778931 0,076922 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04778931 0,07685488 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04778931 0,07678787 ! hair cycle GO:0042633 14 14 0,000 0,04778931 0,07672098 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,04778931 0,07665421 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04778931 0,07658756 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,04778931 0,07652102 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04778931 0,07645459 ! lysosome organization GO:0007040 14 14 0,000 0,04778931 0,07638828 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,04778931 0,07632209 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,04778931 0,07625601 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04778931 0,07619004 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,04778931 0,07612419 ! primary neural tube formation GO:0014020 15 14 0,000 0,04778931 0,07605845 ! peptide cross-linking GO:0018149 14 14 0,000 0,04778931 0,07599283 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04778931 0,07592732 ! base-excision repair GO:0006284 14 14 0,000 0,04778931 0,07586192 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04778931 0,07579664 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04778931 0,07573146 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,04778931 0,0756664 ! formation of primary germ layer GO:0001704 14 14 0,000 0,04778931 0,07560145 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,04778931 0,07553661 ! collagen fibril organization GO:0030199 14 14 0,000 0,04778931 0,07547189 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04778931 0,07540727 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,04778931 0,07534276 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04778931 0,07527837 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04778931 0,07521408 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,04778931 0,07514991 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04778931 0,07508584 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04778931 0,07502188 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04778931 0,07495803 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04778931 0,07489429 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,05111774 0,08004248 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05111774 0,07997453 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05111774 0,0799067 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05111774 0,07983898 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05111774 0,07977138 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05111774 0,07970389 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05111774 0,07963652 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05111774 0,07956926 ! response to vitamin GO:0033273 15 15 0,000 0,05111774 0,07950211 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05111774 0,07943508 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05111774 0,07936816 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05111774 0,07930135 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,05111774 0,07923465 ! ovarian follicle development GO:0001541 15 15 0,000 0,05111774 0,07916807 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05111774 0,0791016 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05111774 0,07903524 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05111774 0,07896899 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05111774 0,07890285 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,05111774 0,07883682 ! heme metabolic process GO:0042168 15 15 0,000 0,05111774 0,0787709 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05111774 0,0787051 ! chromosome condensation GO:0030261 15 15 0,000 0,05111774 0,0786394 ! response to starvation GO:0042594 15 15 0,000 0,05111774 0,07857381 ! response to ionizing radiation GO:0010212 16 15 0,000 0,05111774 0,07850834 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05111774 0,07844297 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05111774 0,07837771 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05111774 0,07831255 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05111774 0,07824751 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05111774 0,07818257 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05111774 0,07811775 ! phospholipid transport GO:0015914 15 15 0,000 0,05111774 0,07805303 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05111774 0,07798841 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05111774 0,07792391 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05111774 0,07785951 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05111774 0,07779521 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05111774 0,07773102 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05111774 0,07766694 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05111774 0,07760297 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05111774 0,0775391 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05111774 0,07747533 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05111774 0,07741167 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05443503 0,08236762 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05443503 0,08230005 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05443503 0,08223259 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05443503 0,08216524 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05443503 0,082098 ! learning GO:0007612 16 16 0,000 0,05443503 0,08203088 ! circadian rhythm GO:0007623 16 16 0,000 0,05443503 0,08196386 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05443503 0,08189695 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05443503 0,08183015 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,05443503 0,08176346 ! vacuole organization GO:0007033 16 16 0,000 0,05443503 0,08169687 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05443503 0,0816304 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05443503 0,08156403 ! vesicle targeting GO:0006903 17 16 0,000 0,05443503 0,08149778 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05443503 0,08143162 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05443503 0,08136558 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05443503 0,08129964 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05443503 0,08123382 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05443503 0,08116809 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05443503 0,08110248 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05443503 0,08103696 ! cell fate specification GO:0001708 16 16 0,000 0,05443503 0,08097156 ! pentose metabolic process GO:0019321 16 16 0,000 0,05443503 0,08090626 ! fatty acid transport GO:0015908 16 16 0,000 0,05443503 0,08084107 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05443503 0,08077598 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,05443503 0,08071099 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05443503 0,08064611 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05443503 0,08058133 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05443503 0,08051666 ! polyol metabolic process GO:0019751 16 16 0,000 0,05443503 0,08045209 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05443503 0,08038763 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05443503 0,08032327 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05443503 0,08025901 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05443503 0,08019485 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,05443503 0,0801308 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05443503 0,08006685 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05443503 0,080003 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05443503 0,07993925 ! regulation of coagulation GO:0050818 17 16 0,000 0,05443503 0,07987561 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0577412 0,08465953 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0577412 0,08459224 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0577412 0,08452505 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0577412 0,08445796 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0577412 0,08439099 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0577412 0,08432412 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0577412 0,08425735 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0577412 0,08419069 ! sensory perception of smell GO:0007608 17 17 0,000 0,0577412 0,08412414 ! glucose transport GO:0015758 17 17 0,000 0,0577412 0,08405769 ! cell junction assembly GO:0034329 18 17 0,000 0,0577412 0,08399135 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0577412 0,08392511 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0577412 0,08385897 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0577412 0,08379294 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0577412 0,08372701 ! response to toxin GO:0009636 18 17 0,000 0,0577412 0,08366119 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0577412 0,08359547 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0577412 0,08352986 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0577412 0,08346434 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0577412 0,08339893 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0577412 0,08333362 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0577412 0,08326842 ! pigmentation GO:0043473 17 17 0,000 0,0577412 0,08320331 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0577412 0,08313831 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0577412 0,08307341 ! embryonic organ development GO:0048568 17 17 0,000 0,0577412 0,08300861 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0577412 0,08294391 ! liver development GO:0001889 17 17 0,000 0,0577412 0,08287931 ! gene silencing GO:0016458 17 17 0,000 0,0577412 0,08281481 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06103629 0,0874727 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06103629 0,08740473 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,06103629 0,08733687 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06103629 0,08726911 ! meiosis I GO:0007127 18 18 0,000 0,06103629 0,08720146 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06103629 0,08713392 ! membrane docking GO:0022406 18 18 0,000 0,06103629 0,08706648 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06103629 0,08699914 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06103629 0,08693191 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06103629 0,08686478 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06103629 0,08679775 ! hexose transport GO:0008645 18 18 0,000 0,06103629 0,08673083 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06103629 0,08666401 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,06103629 0,0865973 ! striated muscle contraction GO:0006941 18 18 0,000 0,06103629 0,08653068 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06103629 0,08646417 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06103629 0,08639776 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06103629 0,08633146 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06103629 0,08626525 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06103629 0,08619915 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06103629 0,08613315 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06103629 0,08606724 ! B cell differentiation GO:0030183 18 18 0,000 0,06103629 0,08600144 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,06103629 0,08593574 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06103629 0,08587014 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06103629 0,08580464 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06103629 0,08573924 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,06103629 0,08567394 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06103629 0,08560874 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,06432034 0,0901463 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06432034 0,0900778 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06432034 0,09000941 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,06432034 0,08994111 ! glial cell differentiation GO:0010001 19 19 0,000 0,06432034 0,08987292 ! regulation of pH GO:0006885 19 19 0,000 0,06432034 0,08980484 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06432034 0,08973686 ! feeding behavior GO:0007631 19 19 0,000 0,06432034 0,08966898 ! peroxisome organization GO:0007031 19 19 0,000 0,06432034 0,0896012 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06432034 0,08953352 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06432034 0,08946595 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06432034 0,08939848 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,06432034 0,08933111 ! metanephros development GO:0001656 19 19 0,000 0,06432034 0,08926385 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06432034 0,08919668 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06432034 0,08912961 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06432034 0,08906265 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06432034 0,08899579 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06432034 0,08892902 ! regulation of protein stability GO:0031647 19 19 0,000 0,06432034 0,08886236 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06432034 0,0887958 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06432034 0,08872933 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06432034 0,08866297 ! eye morphogenesis GO:0048592 19 19 0,000 0,06432034 0,0885967 ! placenta development GO:0001890 19 19 0,000 0,06432034 0,08853054 ! response to heat GO:0009408 19 19 0,000 0,06432034 0,08846447 ! vesicle localization GO:0051648 20 19 0,000 0,06432034 0,0883985 ! regulation of muscle development GO:0048634 21 20 0,000 0,06759338 0,09282757 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,06759338 0,09275845 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,06759338 0,09268943 ! negative regulation of binding GO:0051100 21 20 0,000 0,06759338 0,09262052 ! organic ether metabolic process GO:0018904 20 20 0,000 0,06759338 0,09255171 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,06759338 0,092483 ! neural tube development GO:0021915 21 20 0,000 0,06759338 0,09241439 ! nucleus organization GO:0006997 20 20 0,000 0,06759338 0,09234588 ! phagocytosis GO:0006909 21 20 0,000 0,06759338 0,09227748 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,06759338 0,09220917 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06759338 0,09214097 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06759338 0,09207287 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,06759338 0,09200487 ! chromatin remodeling GO:0006338 20 20 0,000 0,06759338 0,09193697 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06759338 0,09186917 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,06759338 0,09180147 ! lipid oxidation GO:0034440 20 20 0,000 0,06759338 0,09173387 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06759338 0,09166637 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,06759338 0,09159897 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,06759338 0,09153166 ! RNA modification GO:0009451 20 20 0,000 0,06759338 0,09146446 ! single fertilization GO:0007338 21 20 0,000 0,06759338 0,09139736 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06759338 0,09133035 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,07085544 0,09566782 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07085544 0,09559779 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07085544 0,09552786 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07085544 0,09545803 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07085544 0,0953883 ! Notch signaling pathway GO:0007219 22 21 0,000 0,07085544 0,09531867 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07085544 0,09524915 ! ear morphogenesis GO:0042471 21 21 0,000 0,07085544 0,09517972 ! organic anion transport GO:0015711 21 21 0,000 0,07085544 0,0951104 ! cholesterol transport GO:0030301 21 21 0,000 0,07085544 0,09504118 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07085544 0,09497206 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07085544 0,09490304 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,07085544 0,09483412 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07085544 0,0947653 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07085544 0,09469658 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07085544 0,09462796 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07085544 0,09455943 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,07085544 0,09449101 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07085544 0,09442269 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,07085544 0,09435446 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,07085544 0,09428634 ! RNA export from nucleus GO:0006405 22 22 0,000 0,07410657 0,09854142 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,07410657 0,09847037 ! sister chromatid segregation GO:0000819 22 22 0,000 0,07410657 0,09839943 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,07410657 0,09832858 ! regulation of ion transport GO:0043269 22 22 0,000 0,07410657 0,09825784 ! odontogenesis GO:0042476 22 22 0,000 0,07410657 0,09818721 ! cell junction organization GO:0034330 23 22 0,000 0,07410657 0,09811667 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,07410657 0,09804623 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,07410657 0,0979759 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,07410657 0,09790567 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,07410657 0,09783553 ! ovulation cycle process GO:0022602 22 22 0,000 0,07410657 0,0977655 ! spindle organization GO:0007051 22 22 0,000 0,07410657 0,09769557 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,07410657 0,09762574 ! cell chemotaxis GO:0060326 23 22 0,000 0,07410657 0,097556 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,07410657 0,09748637 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,07410657 0,09741684 ! male sex differentiation GO:0046661 22 22 0,000 0,07410657 0,0973474 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,07410657 0,09727807 ! biopolymer methylation GO:0043414 22 22 0,000 0,07410657 0,09720883 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,07410657 0,09713969 ! detection of external stimulus GO:0009581 23 22 0,000 0,07410657 0,09707065 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,07410657 0,09700171 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,07410657 0,09693286 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,07410657 0,09686412 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,07410657 0,09679547 ! aerobic respiration GO:0009060 22 22 0,000 0,07410657 0,09672691 ! cytokine production GO:0001816 22 22 0,000 0,07410657 0,09665846 ! cytokinesis GO:0000910 23 22 0,000 0,07410657 0,0965901 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,07410657 0,09652184 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07734679 0,100671 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07734679 0,10059995 ! viral infectious cycle GO:0019058 23 23 0,000 0,07734679 0,10052901 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,07734679 0,10045816 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07734679 0,10038742 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,07734679 0,10031677 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,07734679 0,10024623 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,07734679 0,10017578 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07734679 0,10010543 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07734679 0,10003518 ! endocrine system development GO:0035270 23 23 0,000 0,07734679 0,09996503 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07734679 0,09989498 ! positive regulation of growth GO:0045927 23 23 0,000 0,07734679 0,09982502 ! female gonad development GO:0008585 23 23 0,000 0,07734679 0,09975517 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,07734679 0,09968541 ! lipid homeostasis GO:0055088 23 23 0,000 0,07734679 0,09961575 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07734679 0,09954618 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,07734679 0,09947671 ! cell projection assembly GO:0030031 25 23 0,000 0,07734679 0,09940734 ! mitochondrial transport GO:0006839 24 24 0,000 0,08057614 0,1034856 ! gliogenesis GO:0042063 24 24 0,000 0,08057614 0,10341353 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,08057614 0,10334157 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08057614 0,1032697 ! glucose homeostasis GO:0042593 24 24 0,000 0,08057614 0,10319794 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08057614 0,10312627 ! T cell differentiation GO:0030217 24 24 0,000 0,08057614 0,10305471 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08057614 0,10298324 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08057614 0,10291187 ! ovulation cycle GO:0042698 24 24 0,000 0,08057614 0,1028406 ! fertilization GO:0009566 25 24 0,000 0,08057614 0,10276943 ! maintenance of protein location GO:0045185 25 24 0,000 0,08057614 0,10269836 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08057614 0,10262739 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,08057614 0,10255651 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08057614 0,10248574 ! glucan metabolic process GO:0044042 25 24 0,000 0,08057614 0,10241506 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,08379466 0,1064325 ! negative regulation of secretion GO:0051048 26 25 0,000 0,08379466 0,1063592 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,08379466 0,106286 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,08379466 0,1062129 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,08379466 0,10613991 ! cellular component disassembly GO:0022411 26 25 0,000 0,08379466 0,10606701 ! endosome transport GO:0016197 25 25 0,000 0,08379466 0,10599421 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,08379466 0,10592151 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,08379466 0,10584891 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,08379466 0,10577641 ! excretion GO:0007588 25 25 0,000 0,08379466 0,10570401 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,08379466 0,10563171 ! gastrulation GO:0007369 25 25 0,000 0,08379466 0,10555951 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,08379466 0,10548741 ! regulation of endocytosis GO:0030100 25 25 0,000 0,08379466 0,1054154 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,08379466 0,10534349 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,08379466 0,10527169 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08700238 0,10922711 ! glycolysis GO:0006096 26 26 0,000 0,08700238 0,10915275 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,08700238 0,1090785 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,08700238 0,10900435 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08700238 0,10893029 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,08700238 0,10885634 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,08700238 0,10878249 ! cellular defense response GO:0006968 26 26 0,000 0,08700238 0,10870874 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08700238 0,10863509 ! double-strand break repair GO:0006302 27 26 0,000 0,08700238 0,10856154 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08700238 0,10848809 ! germ cell development GO:0007281 27 26 0,000 0,08700238 0,10841474 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,08700238 0,10834148 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,08700238 0,10826833 ! response to insulin stimulus GO:0032868 28 26 0,000 0,08700238 0,10819527 ! maintenance of location in cell GO:0051651 27 26 0,000 0,08700238 0,10812231 ! chloride transport GO:0006821 27 27 0,000 0,09019934 0,1120198 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09019934 0,11194437 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,09019934 0,11186903 ! learning or memory GO:0007611 28 27 0,000 0,09019934 0,1117938 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09019934 0,11171867 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09019934 0,11164364 ! peptide metabolic process GO:0006518 29 27 0,000 0,09019934 0,11156871 ! activation of caspase activity GO:0006919 27 27 0,000 0,09019934 0,11149389 ! inner ear development GO:0048839 27 27 0,000 0,09019934 0,11141916 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09019934 0,11134453 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09019934 0,11127 ! cell growth GO:0016049 27 27 0,000 0,09019934 0,11119558 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,09338557 0,11504653 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,09338557 0,11496967 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,09338557 0,11489293 ! carbohydrate transport GO:0008643 28 28 0,000 0,09338557 0,11481628 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,09338557 0,11473973 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,09338557 0,11466329 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,09338557 0,11458695 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,09338557 0,11451071 ! developmental growth GO:0048589 28 28 0,000 0,09338557 0,11443458 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,0965611 0,11824725 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,0965611 0,11816873 ! leukocyte migration GO:0050900 30 29 0,000 0,0965611 0,11809032 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,0965611 0,11801201 ! antigen processing and presentation GO:0019882 29 29 0,000 0,0965611 0,1179338 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,0965611 0,1178557 ! tRNA processing GO:0008033 29 29 0,000 0,0965611 0,1177777 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,0965611 0,11769981 ! adult behavior GO:0030534 30 29 0,000 0,0965611 0,11762201 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,0965611 0,11754432 ! transition metal ion transport GO:0000041 31 30 0,000 0,09972597 0,12131681 ! RNA catabolic process GO:0006401 30 30 0,000 0,09972597 0,12123678 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,09972597 0,12115687 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09972597 0,12107705 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,09972597 0,12099734 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09972597 0,12091774 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09972597 0,12083824 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,09972597 0,12075885 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,09972597 0,12067956 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09972597 0,12060037 ! regulation of ossification GO:0030278 30 30 0,000 0,09972597 0,12052129 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,09972597 0,12044231 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09972597 0,12036344 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09972597 0,12028466 ! vesicle organization GO:0016050 30 30 0,000 0,09972597 0,12020599 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09972597 0,12012743 ! establishment of organelle localization GO:0051656 31 30 0,000 0,09972597 0,12004896 ! regulation of translational initiation GO:0006446 31 31 0,000 0,10288022 0,12376517 ! membrane fusion GO:0006944 31 31 0,000 0,10288022 0,12368443 ! B cell activation GO:0042113 31 31 0,000 0,10288022 0,12360381 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,10288022 0,12352328 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,10288022 0,12344286 ! ion transmembrane transport GO:0034220 31 31 0,000 0,10288022 0,12336255 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,10288022 0,12328234 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,10288022 0,12320223 ! digestion GO:0007586 31 31 0,000 0,10288022 0,12312223 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,10288022 0,12304234 ! regulation of DNA replication GO:0006275 32 31 0,000 0,10288022 0,12296254 ! regulation of heart contraction GO:0008016 31 31 0,000 0,10288022 0,12288285 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,10288022 0,12280326 ! camera-type eye development GO:0043010 31 31 0,000 0,10288022 0,12272378 ! extracellular matrix organization GO:0030198 31 31 0,000 0,10288022 0,1226444 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,10288022 0,12256512 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,10288022 0,12248594 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,10288022 0,12240687 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,10288022 0,1223279 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,10602387 0,12598452 ! cell redox homeostasis GO:0045454 32 32 0,000 0,10602387 0,12590334 ! glucose catabolic process GO:0006007 32 32 0,000 0,10602387 0,12582227 ! lipid modification GO:0030258 32 32 0,000 0,10602387 0,12574131 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,10602387 0,12566044 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,10602387 0,12557968 ! cell maturation GO:0048469 32 32 0,000 0,10602387 0,12549903 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,10602387 0,12541848 ! kidney development GO:0001822 32 32 0,000 0,10602387 0,12533803 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,10602387 0,12525769 ! maintenance of location GO:0051235 33 32 0,000 0,10602387 0,12517744 ! negative regulation of cell size GO:0045792 33 33 0,000 0,10915696 0,12879403 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,10915696 0,12871163 ! amino acid transport GO:0006865 33 33 0,000 0,10915696 0,12862934 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,10915696 0,12854714 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10915696 0,12846506 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,10915696 0,12838308 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,10915696 0,1283012 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,10915696 0,12821943 ! regulation of actin filament length GO:0030832 34 34 0,000 0,11227953 0,1318033 ! response to metal ion GO:0010038 34 34 0,000 0,11227953 0,1317194 ! ear development GO:0043583 34 34 0,000 0,11227953 0,13163561 ! muscle cell differentiation GO:0042692 35 34 0,000 0,11227953 0,13155192 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,11227953 0,13146835 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,11227953 0,13138487 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,11227953 0,13130151 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,11227953 0,13121825 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,11227953 0,13113509 ! secondary metabolic process GO:0019748 34 34 0,000 0,11227953 0,13105204 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,11227953 0,1309691 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,11227953 0,13088626 ! detection of stimulus GO:0051606 36 34 0,000 0,11227953 0,13080353 ! acute inflammatory response GO:0002526 35 35 0,000 0,11539161 0,13434412 ! regulation of cellular component size GO:0032535 35 35 0,000 0,11539161 0,1342593 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,11539161 0,1341746 ! mesoderm development GO:0007498 35 35 0,000 0,11539161 0,13409 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,11539161 0,13400551 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,11539161 0,13392112 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,11539161 0,13383684 ! regulation of immune effector process GO:0002697 35 35 0,000 0,11539161 0,13375267 ! hydrogen transport GO:0006818 36 36 0,000 0,11849323 0,13726149 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,11849323 0,13717527 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,11849323 0,13708916 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,11849323 0,13700315 ! regulation of mitosis GO:0007088 37 36 0,000 0,11849323 0,13691726 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,11849323 0,13683147 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,11849323 0,13674579 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,11849323 0,13666022 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,11849323 0,13657475 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,11849323 0,13648939 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,11849323 0,13640414 ! gonad development GO:0008406 36 36 0,000 0,11849323 0,13631899 ! activation of immune response GO:0002253 36 36 0,000 0,11849323 0,13623395 ! coagulation GO:0050817 39 36 0,000 0,11849323 0,13614902 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,12158443 0,13961377 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,12158443 0,13952684 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,12158443 0,13944002 ! response to drug GO:0042493 37 37 0,000 0,12158443 0,1393533 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,12158443 0,13926669 ! eye development GO:0001654 37 37 0,000 0,12158443 0,13918019 ! negative regulation of growth GO:0045926 37 37 0,000 0,12158443 0,1390938 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,12158443 0,13900751 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,12158443 0,13892133 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,12158443 0,13883526 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,12158443 0,13874929 ! positive regulation of secretion GO:0051047 39 38 0,000 0,12466524 0,142177 ! neurotransmitter transport GO:0006836 40 38 0,000 0,12466524 0,14208908 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,12466524 0,14200126 ! exocytosis GO:0006887 40 38 0,000 0,12466524 0,14191355 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,12466524 0,14182595 ! chromosome segregation GO:0007059 38 38 0,000 0,12466524 0,14173846 ! urogenital system development GO:0001655 38 38 0,000 0,12466524 0,14165107 ! hexose catabolic process GO:0019320 38 38 0,000 0,12466524 0,14156379 ! RNA elongation GO:0006354 38 38 0,000 0,12466524 0,14147662 ! meiotic cell cycle GO:0051321 38 38 0,000 0,12466524 0,14138956 ! regulation of neurological system process GO:0031644 38 38 0,000 0,12466524 0,14130261 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,12466524 0,14121576 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,12773569 0,14460496 ! hemostasis GO:0007599 42 39 0,000 0,12773569 0,14451619 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,12773569 0,14442753 ! activation of MAPK activity GO:0000187 39 39 0,000 0,12773569 0,14433898 ! response to unfolded protein GO:0006986 39 39 0,000 0,12773569 0,14425054 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,12773569 0,1441622 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,12773569 0,14407398 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,12773569 0,14398586 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,12773569 0,14389785 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,12773569 0,14380995 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,12773569 0,14372215 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,12773569 0,14363446 ! developmental maturation GO:0021700 39 39 0,000 0,12773569 0,14354688 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,12773569 0,1434594 ! limb development GO:0060173 39 39 0,000 0,12773569 0,14337203 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,13079582 0,14671741 ! DNA catabolic process GO:0006308 41 40 0,000 0,13079582 0,14662816 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,13079582 0,14653903 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,13079582 0,14645 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,13079582 0,14636108 ! organelle localization GO:0051640 41 40 0,000 0,13079582 0,14627227 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,13384566 0,14959221 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,13384566 0,14950155 ! amine catabolic process GO:0009310 42 41 0,000 0,13384566 0,14941099 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,13384566 0,14932055 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,13384566 0,14923022 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,13384566 0,14914 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,13384566 0,14904988 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,13384566 0,14895987 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,13688524 0,15225076 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,13688524 0,15215893 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,13688524 0,15206721 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,13688524 0,1519756 ! protein ubiquitination GO:0016567 43 42 0,000 0,13688524 0,15188411 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,13688524 0,15179272 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,13688524 0,15170144 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,13688524 0,15161028 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,13688524 0,15151922 ! reproductive structure development GO:0048608 43 43 0,000 0,1399146 0,15477948 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1399146 0,15468663 ! mitochondrion organization GO:0007005 44 43 0,000 0,1399146 0,15459389 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1399146 0,15450126 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1399146 0,15440875 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,1399146 0,15431634 ! humoral immune response GO:0006959 44 44 0,000 0,14293377 0,157552 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,14293377 0,15745782 ! mRNA transport GO:0051028 44 44 0,000 0,14293377 0,15736376 ! protein import into nucleus GO:0006606 44 44 0,000 0,14293377 0,15726981 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,14293377 0,15717598 ! vitamin metabolic process GO:0006766 44 44 0,000 0,14293377 0,15708225 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,14293377 0,15698864 ! amine biosynthetic process GO:0009309 46 45 0,000 0,14594278 0,16019806 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,14594278 0,1601027 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,14594278 0,16000746 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,14594278 0,15991233 ! nuclear import GO:0051170 45 45 0,000 0,14594278 0,15981731 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,14594278 0,15972241 ! protein processing GO:0016485 45 45 0,000 0,14594278 0,15962762 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,14894166 0,16281108 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,14894166 0,16271457 ! tube morphogenesis GO:0035239 47 46 0,000 0,14894166 0,16261818 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,14894166 0,1625219 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,14894166 0,16242573 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,14894166 0,16232968 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,14894166 0,16223374 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,15193045 0,16539151 ! regulation of blood pressure GO:0008217 48 47 0,000 0,15193045 0,16529388 ! sex differentiation GO:0007548 47 47 0,000 0,15193045 0,16519636 ! amine transport GO:0015837 47 47 0,000 0,15193045 0,16509895 ! rhythmic process GO:0048511 47 47 0,000 0,15193045 0,16500167 ! regulation of catabolic process GO:0009894 48 47 0,000 0,15193045 0,16490449 ! calcium ion transport GO:0006816 48 48 0,000 0,15490919 0,16803863 ! actin filament organization GO:0007015 50 48 0,000 0,15490919 0,16793978 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,15490919 0,16784105 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,15490919 0,16774244 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,15490919 0,16764394 ! protein localization in nucleus GO:0034504 48 48 0,000 0,15490919 0,16754556 ! DNA recombination GO:0006310 48 48 0,000 0,15490919 0,16744729 ! leukocyte differentiation GO:0002521 50 49 0,000 0,15787789 0,17055624 ! cell cycle arrest GO:0007050 49 49 0,000 0,15787789 0,17045633 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,15787789 0,17035653 ! divalent metal ion transport GO:0070838 49 49 0,000 0,15787789 0,17025684 ! response to nutrient GO:0007584 49 49 0,000 0,15787789 0,17015728 ! regulation of ligase activity GO:0051340 50 49 0,000 0,15787789 0,17005783 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,15787789 0,1699585 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,15787789 0,16985928 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,1608366 0,17294157 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,1608366 0,17284073 ! negative regulation of transport GO:0051051 51 50 0,000 0,1608366 0,17274 ! RNA transport GO:0050658 50 50 0,000 0,1608366 0,1726394 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,1608366 0,17253891 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,1608366 0,17243854 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,1608366 0,17233828 ! transcription initiation GO:0006352 50 50 0,000 0,1608366 0,17223814 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,1608366 0,17213812 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,16378534 0,17519233 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,16378534 0,17509071 ! positive regulation of immune response GO:0050778 51 51 0,000 0,16378534 0,17498921 ! rRNA metabolic process GO:0016072 51 51 0,000 0,16378534 0,17488782 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,16378534 0,17478656 ! protein maturation GO:0051604 51 51 0,000 0,16378534 0,17468541 ! RNA localization GO:0006403 52 52 0,000 0,16672415 0,17771695 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,16672415 0,17761423 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,16672415 0,17751162 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,16672415 0,17740913 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,16672415 0,17730676 ! sodium ion transport GO:0006814 53 53 0,000 0,16965307 0,18031753 ! tRNA metabolic process GO:0006399 53 53 0,000 0,16965307 0,1802136 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,16965307 0,18010979 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,16965307 0,1800061 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,17257211 0,18299793 ! response to virus GO:0009615 54 54 0,000 0,17257211 0,1828927 ! hormone metabolic process GO:0042445 55 54 0,000 0,17257211 0,18278759 ! sulfur metabolic process GO:0006790 55 54 0,000 0,17257211 0,1826826 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,17548132 0,18565561 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,17548132 0,1855491 ! in utero embryonic development GO:0001701 55 55 0,000 0,17548132 0,1854427 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,17548132 0,18533643 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,17838073 0,18829077 ! reproductive developmental process GO:0003006 56 56 0,000 0,17838073 0,18818299 ! ATP metabolic process GO:0046034 57 57 0,000 0,18127036 0,19112201 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,18127036 0,19101274 ! innate immune response GO:0045087 58 58 0,000 0,18415026 0,19393653 ! dephosphorylation GO:0016311 60 59 0,000 0,18702044 0,19684676 ! carboxylic acid transport GO:0046942 59 59 0,000 0,18702044 0,1967344 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,18702044 0,19662217 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,18702044 0,19651007 ! protein localization in organelle GO:0033365 59 59 0,000 0,18702044 0,1963981 ! immune effector process GO:0002252 59 59 0,000 0,18702044 0,19628626 ! potassium ion transport GO:0006813 60 60 0,000 0,18988094 0,19917506 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,18988094 0,19906176 ! protein polymerization GO:0051258 65 60 0,000 0,18988094 0,1989486 ! cellular respiration GO:0045333 62 61 0,000 0,1927318 0,20182086 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,1927318 0,20170625 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,1927318 0,20159178 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,1927318 0,20147743 ! lipid transport GO:0006869 62 62 0,000 0,19557305 0,2043317 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,19557305 0,20421594 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,19557305 0,2041003 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 0,000 0,19557305 0,20398479 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,19557305 0,20386941 ! regulation of secretion GO:0051046 65 63 0,000 0,19840471 0,20670428 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,19840471 0,2065875 ! glucose metabolic process GO:0006006 63 63 0,000 0,19840471 0,20647085 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,19840471 0,20635433 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,19840471 0,20623794 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,20122681 0,20905356 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,20122681 0,20893578 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,20122681 0,20881814 ! anion transport GO:0006820 65 65 0,000 0,20403939 0,21161767 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,20403939 0,21149865 ! regulation of hormone levels GO:0010817 66 65 0,000 0,20403939 0,21137976 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,20684248 0,21416331 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,20684248 0,21404306 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,20684248 0,21392295 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,20684248 0,21380297 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,20963611 0,21656914 ! muscle contraction GO:0006936 67 67 0,000 0,20963611 0,21644781 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,20963611 0,21632662 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,21242031 0,21907701 ! regulation of cell size GO:0008361 68 68 0,000 0,21242031 0,21895449 ! regulation of translation GO:0006417 69 69 0,000 0,2151951 0,22169065 ! response to nutrient levels GO:0031667 69 69 0,000 0,2151951 0,2215668 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,2151951 0,22144309 ! growth GO:0040007 70 70 0,000 0,21796053 0,22416365 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,21796053 0,22403862 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,22071661 0,22674511 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,22071661 0,22661879 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,22071661 0,22649261 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,22071661 0,22636657 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,22071661 0,22624067 ! secretion by cell GO:0032940 75 72 0,000 0,22346339 0,22892887 ! muscle system process GO:0003012 72 72 0,000 0,22346339 0,22880168 ! sensory organ development GO:0007423 72 72 0,000 0,22346339 0,22867464 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,22346339 0,22854774 ! regulation of cytokine production GO:0001817 72 72 0,000 0,22346339 0,22842098 ! electron transport chain GO:0022900 75 74 0,000 0,22892914 0,23387827 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,22892914 0,2337487 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,23164816 0,236394 ! response to oxidative stress GO:0006979 76 75 0,000 0,23164816 0,23626318 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,23164816 0,2361325 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,234358 0,23876274 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,234358 0,23863083 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,23705868 0,24124746 ! microtubule-based movement GO:0007018 82 78 0,000 0,23975022 0,24385191 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,23975022 0,24371741 ! metal ion homeostasis GO:0055065 78 78 0,000 0,23975022 0,24358306 ! regulation of immune response GO:0050776 78 78 0,000 0,23975022 0,24344885 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,24510604 0,24875024 ! MAPKKK cascade GO:0000165 82 81 0,000 0,24777037 0,2513158 ! lymphocyte activation GO:0046649 82 81 0,000 0,24777037 0,25117756 ! lipid catabolic process GO:0016042 82 81 0,000 0,24777037 0,25103947 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,25307203 0,25627019 ! ncRNA processing GO:0034470 83 83 0,000 0,25307203 0,25612946 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,25570941 0,25865666 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,25833786 0,26117207 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,25833786 0,26102888 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,26095742 0,26353125 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,26095742 0,26338692 ! male gamete generation GO:0048232 90 88 0,000 0,26616996 0,26850095 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,26616996 0,26835407 ! chemotaxis GO:0006935 90 89 0,000 0,268763 0,27082023 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,268763 0,27067224 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,27134725 0,27312561 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,27392276 0,27556749 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,27648954 0,27799793 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,27648954 0,27784635 ! tissue morphogenesis GO:0048729 94 93 0,000 0,27904762 0,28026417 ! regulation of response to stress GO:0080134 97 94 0,000 0,28159703 0,28267065 ! cofactor metabolic process GO:0051186 95 94 0,000 0,28159703 0,28251678 ! endocytosis GO:0006897 99 98 0,000 0,29170855 0,29250209 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,29170855 0,29234304 ! regulation of system process GO:0044057 98 98 0,000 0,29170855 0,29218416 ! anti-apoptosis GO:0006916 100 99 0,000 0,29421503 0,29453466 ! response to hormone stimulus GO:0009725 102 100 0,000 0,29671302 0,2968741 ! hemopoiesis GO:0030097 104 100 0,000 0,29671302 0,29671302