pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6286-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 15 9 3,000 3,965E-09 9,54E-06 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 1,549E-08 1,864E-05 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of locomotion GO:0040017 39 21 3,000 1,842E-07 1,478E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 3,000 2,248E-07 1,352E-04 ! regulation of behavior GO:0050795 43 24 3,000 3,253E-07 1,565E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 3,253E-07 1,304E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 4,56E-07 1,567E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 4,749E-07 1,428E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,62E-06 4,33E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,223E-06 5,349E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,223E-06 4,862E-04 GO:0010829|negative regulation of glucose transport, ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 3,649E-06 7,316E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 4,389E-06 8,123E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 4,879E-06 8,384E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 6,088E-06 9,764E-04 ! cartilage development GO:0051216 90 52 3,000 7,874E-06 1,184E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 9,066E-06 1,283E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,512E-05 2,021E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,761E-05 2,23E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,761E-05 2,118E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,035E-05 2,332E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,169E-05 2,372E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 2,169E-05 2,269E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,3E-05 2,306E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 2,885E-05 2,776E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 4,159E-05 3,849E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 4,285E-05 3,818E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 4,589E-05 3,943E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,768E-05 4,785E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,768E-05 4,626E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,768E-05 4,476E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,443E-05 4,844E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 7,074E-05 5,158E-03 GO:0060326|cell chemotaxis, ! oligosaccharide biosynthetic process GO:0009312 10 6 1,000 8,638E-05 6,113E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,207E-04 8,3E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,207E-04 8,069E-03 GO:0043489|RNA stabilization, ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,573E-04 0,01022605 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,607E-04 0,01017699 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,607E-04 9,916E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,607E-04 9,668E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,607E-04 9,432E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,607E-04 9,208E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,607E-04 8,994E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,607E-04 8,789E-03 ! leukocyte migration GO:0050900 68 45 2,000 1,802E-04 9,634E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,924E-04 0,01006487 ! positive regulation of defense response GO:0031349 76 47 2,000 2,052E-04 0,01050409 ! motor axon guidance GO:0008045 16 9 1,000 2,063E-04 0,01034246 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 2,063E-04 0,01013139 ! retinal ganglion cell axon guidance GO:0031290 13 9 1,000 2,063E-04 9,929E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,185E-04 0,01030766 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,185E-04 0,01010944 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,185E-04 9,919E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,323E-04 0,0103519 ! histone modification GO:0016570 91 50 2,000 2,467E-04 0,01079366 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,575E-04 0,01106381 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,575E-04 0,01086971 ! lung alveolus development GO:0048286 26 10 1,000 2,575E-04 0,0106823 ! regulation of bone resorption GO:0045124 25 10 1,000 2,575E-04 0,01050124 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,575E-04 0,01032622 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,575E-04 0,01015694 ! localization within membrane GO:0051668 20 10 1,000 2,575E-04 9,993E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,617E-04 9,995E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 2,000 2,772E-04 0,01042266 ! covalent chromatin modification GO:0016569 101 52 2,000 2,772E-04 0,01026231 ! response to UV GO:0009411 104 53 2,000 2,934E-04 0,01069464 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,142E-04 0,01128459 ! blood vessel remodeling GO:0001974 29 11 1,000 3,142E-04 0,01111864 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 3,142E-04 0,0109575 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,142E-04 0,01080097 ! ventral spinal cord development GO:0021517 21 11 1,000 3,142E-04 0,01064884 ! regulation of leukocyte migration GO:0002685 26 11 1,000 3,142E-04 0,01050094 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 3,639E-04 0,01199351 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,639E-04 0,01183144 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,765E-04 0,0120781 ! cartilage condensation GO:0001502 20 12 1,000 3,765E-04 0,01191918 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,765E-04 0,01176438 ! histone acetylation GO:0016573 26 12 1,000 3,765E-04 0,01161356 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,765E-04 0,01146655 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,765E-04 0,01132322 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,765E-04 0,01118342 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 4,029E-04 0,01182161 ! regulation of heart contraction GO:0008016 110 60 2,000 4,234E-04 0,01227255 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 4,234E-04 0,01212645 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,234E-04 0,01198379 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,443E-04 0,01242882 ! regulation of mRNA stability GO:0043488 31 13 1,000 4,443E-04 0,01228596 ! positive regulation of cell motion GO:0051272 146 64 2,000 5,119E-04 0,01399576 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 5,175E-04 0,01398954 ! regulation of RNA stability GO:0043487 32 14 1,000 5,175E-04 0,0138341 ! lung development GO:0030324 144 67 2,000 5,855E-04 0,01548093 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 5,962E-04 0,01559092 ! histone deacetylation GO:0016575 20 15 1,000 5,962E-04 0,01542328 ! respiratory tube development GO:0030323 150 70 2,000 6,656E-04 0,01703628 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 6,803E-04 0,01722846 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 6,803E-04 0,01704899 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 6,803E-04 0,01687323 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 7,227E-04 0,01774202 ! respiratory system development GO:0060541 153 72 2,000 7,227E-04 0,01756281 ! axon guidance GO:0007411 139 73 2,000 7,523E-04 0,01810094 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 7,698E-04 0,01833685 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 7,698E-04 0,01815708 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 7,698E-04 0,0179808 ! neural crest cell migration GO:0001755 37 17 1,000 7,698E-04 0,0178079 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 7,698E-04 0,01763831 ! cell-matrix adhesion GO:0007160 163 75 2,000 8,14E-04 0,0184753 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 8,14E-04 0,01830264 ! defense response to bacterium GO:0042742 89 76 2,000 8,459E-04 0,01884567 ! oligosaccharide metabolic process GO:0009311 34 18 1,000 8,646E-04 0,01908494 ! neuromuscular junction development GO:0007528 34 19 1,000 9,648E-04 0,02110319 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 9,648E-04 0,02091307 ! response to hypoxia GO:0001666 171 81 2,000 1,018E-03 0,02186503 ! cell-substrate adhesion GO:0031589 171 81 2,000 1,018E-03 0,02167154 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 1,07E-03 0,02258979 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,07E-03 0,02239336 ! protein amino acid deacetylation GO:0006476 29 20 1,000 1,07E-03 0,02220031 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,07E-03 0,02201057 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,07E-03 0,02182404 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 1,000 1,07E-03 0,02164064 ! pancreas development GO:0031016 35 20 1,000 1,07E-03 0,0214603 ! response to oxygen levels GO:0070482 176 83 2,000 1,092E-03 0,02171966 ! negative regulation of transport GO:0051051 153 84 2,000 1,131E-03 0,02230081 ! nucleosome assembly GO:0006334 122 85 2,000 1,17E-03 0,02288908 ! chromatin assembly GO:0031497 124 86 2,000 1,21E-03 0,02348443 ! positive regulation of protein modification process GO:0031401 136 88 2,000 1,293E-03 0,02489382 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 1,297E-03 0,02477097 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,297E-03 0,02457592 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,297E-03 0,02438392 ! ossification GO:0001503 188 90 2,000 1,38E-03 0,02573493 ! protein-DNA complex assembly GO:0065004 130 90 2,000 1,38E-03 0,02553697 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,419E-03 0,02605374 ! bone development GO:0060348 189 91 2,000 1,424E-03 0,02596246 ! regulation of defense response GO:0031347 149 92 2,000 1,47E-03 0,02658975 ! nucleosome organization GO:0034728 138 92 2,000 1,47E-03 0,02639132 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,516E-03 0,02702222 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,545E-03 0,02733445 ! vesicle docking GO:0048278 47 24 1,000 1,545E-03 0,02713493 ! spinal cord development GO:0021510 47 24 1,000 1,545E-03 0,0269383 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,545E-03 0,0267445 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,612E-03 0,02769785 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,677E-03 0,02861289 ! myelination GO:0042552 45 25 1,000 1,677E-03 0,02841139 ! vasculogenesis GO:0001570 46 25 1,000 1,677E-03 0,02821271 ! neural crest cell development GO:0014032 54 25 1,000 1,677E-03 0,02801679 GO:0014033|neural crest cell differentiation, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 1,677E-03 0,02782357 ! somitogenesis GO:0001756 43 25 1,000 1,677E-03 0,027633 ! interphase GO:0051325 213 98 2,000 1,762E-03 0,02883617 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,814E-03 0,02948498 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,814E-03 0,02928709 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,814E-03 0,0290922 GO:0060538|skeletal muscle organ development, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,956E-03 0,03116227 ! neuron fate commitment GO:0048663 48 27 1,000 1,956E-03 0,03095725 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 1,956E-03 0,03075492 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,956E-03 0,03055521 ! protein amino acid acylation GO:0043543 55 27 1,000 1,956E-03 0,03035808 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 1,956E-03 0,03016348 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 1,956E-03 0,02997135 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,255E-03 0,03434057 ! membrane docking GO:0022406 61 30 1,000 2,412E-03 0,03650487 ! ensheathment of neurons GO:0007272 57 30 1,000 2,412E-03 0,03627671 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,412E-03 0,03605139 ! regulation of B cell activation GO:0050864 50 30 1,000 2,412E-03 0,03582885 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 2,575E-03 0,0380053 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,742E-03 0,04022879 ! peripheral nervous system development GO:0007422 64 32 1,000 2,742E-03 0,03998498 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 3,274E-03 0,04745365 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,274E-03 0,04716949 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,461E-03 0,0495693 ! tissue remodeling GO:0048771 76 37 1,000 3,653E-03 0,05201036 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 3,85E-03 0,05449163 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 4,052E-03 0,05701204 ! segmentation GO:0035282 67 39 1,000 4,052E-03 0,05668058 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,052E-03 0,05635294 ! mesenchymal cell development GO:0014031 87 40 1,000 4,259E-03 0,05888587 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,47E-03 0,0614558 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,47E-03 0,06110662 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,686E-03 0,06369986 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 4,686E-03 0,063342 ! neuron migration GO:0001764 79 42 1,000 4,686E-03 0,06298813 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 5,598E-03 0,0748279 ! positive regulation of protein transport GO:0051222 72 46 1,000 5,598E-03 0,07441449 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,838E-03 0,0771742 ! vascular process in circulatory system GO:0003018 80 47 1,000 5,838E-03 0,07675248 ! protein homooligomerization GO:0051260 76 47 1,000 5,838E-03 0,07633535 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,082E-03 0,07910017 ! regulation of action potential GO:0001508 95 49 1,000 6,331E-03 0,08189487 ! negative regulation of immune system process GO:0002683 95 50 1,000 6,585E-03 0,0847187 ! positive regulation of binding GO:0051099 78 51 1,000 6,843E-03 0,08757087 ! regulation of cell shape GO:0008360 125 51 1,000 6,843E-03 0,08710754 ! regulation of angiogenesis GO:0045765 114 52 1,000 7,105E-03 0,08997461 ! synapse organization GO:0050808 85 52 1,000 7,105E-03 0,08950354 ! activation of phospholipase C activity GO:0007202 103 54 1,000 7,644E-03 0,09578868 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 7,92E-03 0,09873428 ! heart morphogenesis GO:0003007 97 55 1,000 7,92E-03 0,09822534 ! nuclear export GO:0051168 97 55 1,000 7,92E-03 0,09772162 ! skeletal muscle fiber development GO:0048741 111 56 1,000 8,201E-03 0,10066689 ! regulation of bone remodeling GO:0046850 137 57 1,000 8,486E-03 0,10363631 ! muscle fiber development GO:0048747 112 57 1,000 8,486E-03 0,10311289 ! regulation of phospholipase activity GO:0010517 106 57 1,000 8,486E-03 0,10259474 ! regulation of intracellular transport GO:0032386 101 57 1,000 8,486E-03 0,10208176 ! regulation of tissue remodeling GO:0034103 140 58 1,000 8,775E-03 0,10503777 ! positive regulation of lipase activity GO:0060193 108 58 1,000 8,775E-03 0,10451778 ! skeletal system morphogenesis GO:0048705 105 59 1,000 9,069E-03 0,10748458 ! regulation of protein complex assembly GO:0043254 117 61 1,000 9,669E-03 0,11404088 ! viral reproductive process GO:0022415 126 62 1,000 9,976E-03 0,11708498 ! regulation of homeostatic process GO:0032844 134 62 1,000 9,976E-03 0,11651661 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01157385 0,13452506 ! adaptive immune response GO:0002250 119 67 1,000 0,01157385 0,1338783 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,01190604 0,13706193 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01190604 0,13640925 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01206159 0,13753641 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01206159 0,13688765 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01206159 0,13624498 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01206159 0,13560833 ! neuron fate determination GO:0048664 7 5 0,000 0,01206159 0,13497759 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01206159 0,13435269 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01206159 0,13373356 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01206159 0,1331201 ! polyol transport GO:0015791 12 5 0,000 0,01206159 0,13251225 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01206159 0,13190992 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01206159 0,13131304 ! response to superoxide GO:0000303 10 5 0,000 0,01206159 0,13072154 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01206159 0,13013534 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01206159 0,12955438 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01206159 0,12897859 ! female meiosis GO:0007143 7 5 0,000 0,01206159 0,12840788 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01206159 0,12784221 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01206159 0,1272815 ! cobalt ion transport GO:0006824 11 5 0,000 0,01206159 0,12672568 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01206159 0,1261747 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01206159 0,12562849 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01206159 0,12508699 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01206159 0,12455014 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01206159 0,12401787 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01206159 0,12349013 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01206159 0,12296687 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01206159 0,12244802 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01206159 0,12193354 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01206159 0,12142335 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01206159 0,12091742 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01206159 0,12041569 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01206159 0,11991811 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01206159 0,11942462 ! negative chemotaxis GO:0050919 14 5 0,000 0,01206159 0,11893517 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01206159 0,11844972 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01206159 0,11796822 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01206159 0,11749061 ! behavioral response to pain GO:0048266 9 5 0,000 0,01206159 0,11701686 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01206159 0,11654691 ! Notch receptor processing GO:0007220 8 5 0,000 0,01206159 0,11608073 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01206159 0,11561825 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01206159 0,11515945 ! micturition GO:0060073 9 5 0,000 0,01206159 0,11470428 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01206159 0,11425268 ! copulation GO:0007620 9 5 0,000 0,01206159 0,11380463 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01206159 0,11336008 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01206159 0,112919 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01206159 0,11248132 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01206159 0,11204703 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01206159 0,11161608 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01206159 0,11118844 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01206159 0,11076405 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01206159 0,1103429 ! grooming behavior GO:0007625 6 5 0,000 0,01206159 0,10992493 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01206159 0,10951012 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01206159 0,10909843 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01206159 0,10868982 ! response to protozoan GO:0001562 10 5 0,000 0,01206159 0,10828426 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01206159 0,10788172 ! lymph vessel development GO:0001945 10 5 0,000 0,01206159 0,10748215 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01206159 0,10708554 ! endochondral ossification GO:0001958 16 5 0,000 0,01206159 0,10669184 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01206159 0,10630103 ! parathyroid gland development GO:0060017 13 5 0,000 0,01206159 0,10591307 ! anagen GO:0042640 6 5 0,000 0,01206159 0,10552793 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01206159 0,10514559 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01206159 0,104766 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01206159 0,10438914 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01206159 0,10401499 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01206159 0,10364351 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01206159 0,10327467 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01206159 0,10290845 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01206159 0,10254481 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01206159 0,10218374 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01206159 0,1018252 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01206159 0,10146917 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01206159 0,10111562 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01206159 0,10076452 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01206159 0,10041585 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01206159 0,10006959 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01206159 0,09972571 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01206159 0,09938418 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01206159 0,09904499 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01206159 0,0987081 ! histidine catabolic process GO:0006548 6 5 0,000 0,01206159 0,0983735 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01206159 0,09804115 ! microvillus organization GO:0032528 7 5 0,000 0,01206159 0,09771105 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01206159 0,09738316 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01206159 0,09705746 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01206159 0,09673394 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01206159 0,09641256 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01206159 0,09609332 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01206159 0,09577618 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01206159 0,09546112 ! polyol catabolic process GO:0046174 7 5 0,000 0,01206159 0,09514814 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01206159 0,0948372 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01206159 0,09452828 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01206159 0,09422137 ! muscle cell migration GO:0014812 8 5 0,000 0,01206159 0,09391645 ! mitochondrial fission GO:0000266 8 5 0,000 0,01206159 0,09361349 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01206159 0,09331248 ! mRNA transcription GO:0009299 9 5 0,000 0,01206159 0,0930134 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01206159 0,09271624 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01206159 0,09242096 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01206159 0,09212756 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01206159 0,09183602 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01206159 0,09154631 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01206159 0,09125843 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01206159 0,09097236 ! response to food GO:0032094 6 5 0,000 0,01206159 0,09068807 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01206159 0,09040555 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01206159 0,09012479 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01206159 0,08984576 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01206159 0,08956846 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01206159 0,08929287 ! forebrain neuron development GO:0021884 13 5 0,000 0,01206159 0,08901896 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01206159 0,08874673 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01206159 0,08847616 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01206159 0,08820724 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01206159 0,08793994 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01206159 0,08767427 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01206159 0,08741019 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01206159 0,08714769 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01206159 0,08688677 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01206159 0,08662741 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01206159 0,08636959 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01206159 0,0861133 ! basic amino acid transport GO:0015802 11 5 0,000 0,01206159 0,08585853 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01206159 0,08560526 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01206159 0,08535348 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01206159 0,08510317 ! depyrimidination GO:0045008 10 5 0,000 0,01206159 0,08485433 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01206159 0,08460694 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01206159 0,08436099 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01206159 0,08411647 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01206159 0,08387336 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01206159 0,08363165 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01206159 0,08339133 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01206159 0,08315238 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01206159 0,0829148 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01206159 0,08267858 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01206159 0,0824437 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01206159 0,08221015 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01206159 0,08197791 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01206159 0,08174699 ! response to arsenic GO:0046685 10 5 0,000 0,01206159 0,08151736 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01206159 0,08128902 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01206159 0,08106196 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01206159 0,08083616 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01206159 0,08061162 ! response to cadmium ion GO:0046686 7 5 0,000 0,01206159 0,08038832 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01206159 0,08016625 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01206159 0,0799454 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01206159 0,07972577 ! decidualization GO:0046697 11 5 0,000 0,01206159 0,07950735 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01206159 0,07929011 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01206159 0,07907406 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01206159 0,07885919 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01206159 0,07864548 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01206159 0,07843292 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01206159 0,07822151 ! neural tube patterning GO:0021532 7 5 0,000 0,01206159 0,07801124 ! embryonic cleavage GO:0040016 6 5 0,000 0,01206159 0,0778021 ! peroxisome fission GO:0016559 5 5 0,000 0,01206159 0,07759407 ! histone demethylation GO:0016577 10 5 0,000 0,01206159 0,07738715 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01206159 0,07718133 ! mitotic recombination GO:0006312 9 5 0,000 0,01206159 0,07697661 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01206159 0,07677297 ! metaphase plate congression GO:0051310 7 5 0,000 0,01206159 0,0765704 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01206159 0,0763689 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01206159 0,07616846 ! enteric nervous system development GO:0048484 8 5 0,000 0,01206159 0,07596906 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01206159 0,07577071 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01206159 0,07557339 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01206159 0,0753771 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01206159 0,07518182 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01206159 0,07498755 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01206159 0,07479428 ! plasminogen activation GO:0031639 5 5 0,000 0,01206159 0,07460201 ! B cell homeostasis GO:0001782 13 5 0,000 0,01206159 0,07441072 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01206159 0,07422041 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01206159 0,07403108 ! metaphase GO:0051323 8 5 0,000 0,01206159 0,0738427 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01206159 0,07365528 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01206159 0,07346881 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01206159 0,07328329 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01206159 0,07309869 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01206159 0,07291503 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01206159 0,07273229 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01206159 0,07255045 ! response to redox state GO:0051775 5 5 0,000 0,01206159 0,07236953 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01206159 0,07218951 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01206159 0,07201038 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01206159 0,07183213 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01206159 0,07165477 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01206159 0,07147828 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01206159 0,07130266 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01206159 0,0711279 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01206159 0,07095399 ! striatum development GO:0021756 9 5 0,000 0,01206159 0,07078093 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01206159 0,07060871 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01206159 0,07043733 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01206159 0,07026678 ! glial cell migration GO:0008347 11 5 0,000 0,01206159 0,07009706 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01206159 0,06992815 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01206159 0,06976005 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01206159 0,06959276 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01206159 0,06942627 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01206159 0,06926058 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01206159 0,06909567 ! neuroprotection GO:0043526 6 5 0,000 0,01206159 0,06893155 ! neural plate development GO:0001840 8 5 0,000 0,01206159 0,0687682 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01206159 0,06860563 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01206159 0,06844382 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01206159 0,06828278 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01206159 0,06812249 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01206159 0,06796295 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01206159 0,06780416 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01206159 0,06764611 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01206159 0,06748879 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01206159 0,06733221 ! spindle assembly GO:0051225 6 5 0,000 0,01206159 0,06717635 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01206159 0,0670212 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01206159 0,06686678 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01206159 0,06671306 ! drug metabolic process GO:0017144 6 5 0,000 0,01206159 0,06656005 ! stem cell division GO:0017145 11 5 0,000 0,01206159 0,06640774 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01206159 0,06625612 ! organ regeneration GO:0031100 7 5 0,000 0,01206159 0,0661052 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01206159 0,06595496 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01206159 0,0658054 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01206159 0,06565652 ! negative regulation of cell size GO:0045792 134 69 1,000 0,0122424 0,06649032 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01327622 0,07194274 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01398584 0,07561783 GO:0090046|regulation of transcription regulator activity, ! exocytosis GO:0006887 133 74 1,000 0,01398584 0,07544829 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01398584 0,0752795 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01445663 0,07763985 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01445663 0,07746693 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01445663 0,07729478 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01445663 0,0771234 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01445663 0,07695277 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01445663 0,0767829 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01445663 0,07661377 ! sleep GO:0030431 13 6 0,000 0,01445663 0,07644539 ! response to oxygen radical GO:0000305 11 6 0,000 0,01445663 0,07627775 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01445663 0,07611084 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01445663 0,07594466 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01445663 0,0757792 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01445663 0,07561446 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01445663 0,07545044 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01445663 0,07528713 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01445663 0,07512452 ! forebrain regionalization GO:0021871 8 6 0,000 0,01445663 0,07496261 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01445663 0,0748014 ! male meiosis GO:0007140 7 6 0,000 0,01445663 0,07464089 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01445663 0,07448106 ! response to zinc ion GO:0010043 9 6 0,000 0,01445663 0,07432191 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01445663 0,07416344 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01445663 0,07400564 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01445663 0,07384852 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01445663 0,07369206 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01445663 0,07353626 ! malate metabolic process GO:0006108 11 6 0,000 0,01445663 0,07338112 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01445663 0,07322664 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01445663 0,0730728 ! protein refolding GO:0042026 15 6 0,000 0,01445663 0,07291961 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01445663 0,07276706 ! opsonization GO:0008228 8 6 0,000 0,01445663 0,07261514 ! mating behavior GO:0007617 7 6 0,000 0,01445663 0,07246386 ! neuron remodeling GO:0016322 15 6 0,000 0,01445663 0,07231321 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01445663 0,07216318 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01445663 0,07201377 ! equilibrioception GO:0050957 14 6 0,000 0,01445663 0,07186498 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01445663 0,07171681 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01445663 0,07156924 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01445663 0,07142228 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01445663 0,07127593 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01445663 0,07113017 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01445663 0,07098501 ! toxin metabolic process GO:0009404 11 6 0,000 0,01445663 0,07084043 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01445663 0,07069645 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01445663 0,07055305 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01445663 0,07041023 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01445663 0,07026799 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01445663 0,07012632 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01445663 0,06998522 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01445663 0,06984468 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01445663 0,06970471 ! thymic T cell selection GO:0045061 12 6 0,000 0,01445663 0,06956531 ! protein lipoylation GO:0009249 10 6 0,000 0,01445663 0,06942645 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01445663 0,06928815 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01445663 0,0691504 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01445663 0,0690132 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01445663 0,06887654 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01445663 0,06874042 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01445663 0,06860484 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01445663 0,06846979 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01445663 0,06833527 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01445663 0,06820128 ! hyperosmotic response GO:0006972 9 6 0,000 0,01445663 0,06806781 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01445663 0,06793487 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01445663 0,06780244 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01445663 0,06767053 ! urea metabolic process GO:0019627 7 6 0,000 0,01445663 0,06753913 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01445663 0,06740824 ! neutrophil activation GO:0042119 8 6 0,000 0,01445663 0,06727786 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01445663 0,06714798 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01445663 0,0670186 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01445663 0,06688972 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01445663 0,06676133 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01445663 0,06663343 ! neuron apoptosis GO:0051402 9 6 0,000 0,01445663 0,06650603 ! nucleoside salvage GO:0043174 9 6 0,000 0,01445663 0,06637911 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01445663 0,06625267 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01445663 0,06612672 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01445663 0,06600124 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01445663 0,06587624 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01445663 0,06575171 ! carnitine transport GO:0015879 10 6 0,000 0,01445663 0,06562765 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01445663 0,06550405 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01445663 0,06538093 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01445663 0,06525826 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01445663 0,06513605 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01445663 0,0650143 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01445663 0,06489301 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01445663 0,06477217 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01445663 0,06465177 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01445663 0,06453182 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01445663 0,06441232 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01445663 0,06429326 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01445663 0,06417464 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01445663 0,06405645 ! neural nucleus development GO:0048857 14 6 0,000 0,01445663 0,0639387 ! response to UV-C GO:0010225 11 6 0,000 0,01445663 0,06382138 ! astrocyte development GO:0014002 15 6 0,000 0,01445663 0,06370449 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01445663 0,06358803 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01445663 0,06347199 ! interaction with symbiont GO:0051702 13 6 0,000 0,01445663 0,06335638 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01445663 0,06324119 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01445663 0,06312641 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01445663 0,06301205 ! response to copper ion GO:0046688 10 6 0,000 0,01445663 0,06289811 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01445663 0,06278457 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01445663 0,06267145 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01445663 0,06255873 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01445663 0,06244641 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01445663 0,0623345 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01445663 0,06222299 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01445663 0,06211188 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01445663 0,06200116 ! hair follicle maturation GO:0048820 7 6 0,000 0,01445663 0,06189084 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01445663 0,06178091 ! Schwann cell development GO:0014044 15 6 0,000 0,01445663 0,06167137 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01445663 0,06156222 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01445663 0,06145345 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01445663 0,06134507 ! subpallium development GO:0021544 10 6 0,000 0,01445663 0,06123706 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01445663 0,06112944 ! histone ubiquitination GO:0016574 8 6 0,000 0,01445663 0,0610222 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01445663 0,06091533 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01445663 0,06080883 ! G2 phase GO:0051319 16 6 0,000 0,01445663 0,06070271 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01445663 0,06059696 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01445663 0,06049157 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01445663 0,06038655 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01445663 0,06028189 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01445663 0,0601776 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01445663 0,06007367 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01445663 0,05997009 ! receptor internalization GO:0031623 10 6 0,000 0,01445663 0,05986687 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01445663 0,05976401 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01445663 0,0596615 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01445663 0,05955934 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01445663 0,05945753 ! protein deubiquitination GO:0016579 14 6 0,000 0,01445663 0,05935606 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01445663 0,05925495 ! protein destabilization GO:0031648 9 6 0,000 0,01445663 0,05915417 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01445663 0,05905374 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01445663 0,05895365 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01445663 0,0588539 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01445663 0,05875448 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01445663 0,0586554 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01445663 0,05855665 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01445663 0,05845824 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01445663 0,05836016 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01445663 0,0582624 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01445663 0,05816497 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01445663 0,05806787 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01445663 0,05797109 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01445663 0,05787463 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01445663 0,05777849 ! catecholamine transport GO:0051937 9 6 0,000 0,01445663 0,05768267 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01445663 0,05758717 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01445663 0,05749199 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01445663 0,05739712 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01445663 0,05730256 ! maternal placenta development GO:0001893 12 6 0,000 0,01445663 0,05720831 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01445663 0,05711437 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01445663 0,05702074 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01445663 0,05692742 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01445663 0,0568344 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01445663 0,05674168 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01445663 0,05664927 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01445663 0,05655716 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01508048 0,058902 ! protein oligomerization GO:0051259 139 78 1,000 0,01545333 0,06026046 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01583012 0,06162989 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,01659548 0,06450522 ! tRNA transcription GO:0009304 14 7 0,000 0,01684595 0,06537314 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01684595 0,06526787 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01684595 0,06516293 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01684595 0,06505834 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01684595 0,06495408 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01684595 0,06485015 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01684595 0,06474656 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01684595 0,06464329 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01684595 0,06454036 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01684595 0,06443775 ! prostate gland development GO:0030850 13 7 0,000 0,01684595 0,06433547 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01684595 0,06423351 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01684595 0,06413187 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01684595 0,06403056 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01684595 0,06392957 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01684595 0,06382889 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01684595 0,06372853 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01684595 0,06362848 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01684595 0,06352875 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01684595 0,06342933 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01684595 0,06333023 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01684595 0,06323143 ! glycolipid transport GO:0046836 10 7 0,000 0,01684595 0,06313294 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01684595 0,06303475 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01684595 0,06293687 ! neuron adhesion GO:0007158 12 7 0,000 0,01684595 0,06283929 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01684595 0,06274202 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01684595 0,06264505 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01684595 0,06254837 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01684595 0,062452 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01684595 0,06235592 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01684595 0,06226013 ! pericardium development GO:0060039 14 7 0,000 0,01684595 0,06216464 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01684595 0,06206944 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01684595 0,06197453 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01684595 0,06187992 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01684595 0,06178559 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01684595 0,06169154 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01684595 0,06159779 ! lipoprotein transport GO:0042953 14 7 0,000 0,01684595 0,06150432 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01684595 0,06141113 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01684595 0,06131822 ! rhythmic behavior GO:0007622 15 7 0,000 0,01684595 0,0612256 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01684595 0,06113325 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01684595 0,06104118 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01684595 0,06094939 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01684595 0,06085788 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01684595 0,06076663 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01684595 0,06067567 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01684595 0,06058497 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01684595 0,06049454 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01684595 0,06040439 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01684595 0,0603145 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01684595 0,06022488 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01684595 0,06013553 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01684595 0,06004644 ! spinal cord patterning GO:0021511 13 7 0,000 0,01684595 0,05995761 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01684595 0,05986905 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01684595 0,05978074 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01684595 0,0596927 ! adrenal gland development GO:0030325 17 7 0,000 0,01684595 0,05960492 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01684595 0,05951739 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01684595 0,05943012 ! ovulation GO:0030728 9 7 0,000 0,01684595 0,05934311 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01684595 0,05925635 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01684595 0,05916985 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01684595 0,05908359 ! microtubule nucleation GO:0007020 20 7 0,000 0,01684595 0,05899759 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01684595 0,05891184 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01684595 0,05882633 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01684595 0,05874108 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01684595 0,05865607 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01684595 0,05857131 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01684595 0,05848679 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01684595 0,05840251 ! galactose metabolic process GO:0006012 13 7 0,000 0,01684595 0,05831848 ! vesicle fusion GO:0006906 17 7 0,000 0,01684595 0,05823469 ! response to dietary excess GO:0002021 8 7 0,000 0,01684595 0,05815114 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01684595 0,05806783 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01684595 0,05798476 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01684595 0,05790192 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01684595 0,05781932 ! organ growth GO:0035265 15 7 0,000 0,01684595 0,05773696 ! purine salvage GO:0043101 10 7 0,000 0,01684595 0,05765483 ! nucleoside transport GO:0015858 8 7 0,000 0,01684595 0,05757293 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01684595 0,05749127 ! parturition GO:0007567 14 7 0,000 0,01684595 0,05740984 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01684595 0,05732863 ! rRNA modification GO:0000154 14 7 0,000 0,01684595 0,05724766 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01684595 0,05716692 ! spindle checkpoint GO:0031577 15 7 0,000 0,01684595 0,0570864 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01684595 0,05700611 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01684595 0,05692605 ! macrophage differentiation GO:0030225 11 7 0,000 0,01684595 0,05684621 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01684595 0,05676659 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01684595 0,0566872 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01684595 0,05660802 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01684595 0,05652907 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01684595 0,05645034 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01684595 0,05637183 ! fibrinolysis GO:0042730 10 7 0,000 0,01684595 0,05629353 ! eating behavior GO:0042755 7 7 0,000 0,01684595 0,05621546 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01684595 0,0561376 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01684595 0,05605995 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01684595 0,05598252 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01684595 0,0559053 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01684595 0,0558283 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01684595 0,05575151 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01684595 0,05567492 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01684595 0,05559855 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01684595 0,05552239 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01684595 0,05544644 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01684595 0,05537069 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01684595 0,05529515 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01684595 0,05521982 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01684595 0,05514469 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01684595 0,05506976 ! regulation of meiosis GO:0040020 12 7 0,000 0,01684595 0,05499504 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01684595 0,05492052 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01684595 0,0548462 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01684595 0,05477209 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01684595 0,05469817 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01684595 0,05462445 ! transcription termination GO:0006353 13 7 0,000 0,01684595 0,05455094 ! response to tumor cell GO:0002347 13 7 0,000 0,01684595 0,05447761 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01684595 0,05440449 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01684595 0,05433156 ! anaphase GO:0051322 17 7 0,000 0,01684595 0,05425883 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01684595 0,05418629 ! axonal fasciculation GO:0007413 18 7 0,000 0,01684595 0,05411394 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01684595 0,05404179 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01684595 0,05396983 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01684595 0,05389806 ! diuresis GO:0030146 12 7 0,000 0,01684595 0,05382649 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01684595 0,0537551 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01684595 0,0536839 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01684595 0,05361289 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01684595 0,05354207 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01684595 0,05347143 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01684595 0,05340098 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01684595 0,05333072 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01684595 0,05326064 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01684595 0,05319074 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01684595 0,05312103 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01684595 0,0530515 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01684595 0,05298215 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01684595 0,05291298 ! lymph node development GO:0048535 10 7 0,000 0,01684595 0,052844 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01684595 0,05277519 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01684595 0,05270656 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01684595 0,05263811 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01684595 0,05256984 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01684595 0,05250174 ! adult feeding behavior GO:0008343 9 7 0,000 0,01684595 0,05243382 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01684595 0,05236608 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01684595 0,05229851 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01684595 0,05223111 ! muscle adaptation GO:0043500 14 7 0,000 0,01684595 0,05216389 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01684595 0,05209684 ! retina homeostasis GO:0001895 12 7 0,000 0,01684595 0,05202997 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01684595 0,05196326 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01684595 0,05189673 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01684595 0,05183036 ! protein prenylation GO:0018342 18 7 0,000 0,01684595 0,05176417 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01684595 0,05169814 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01684595 0,05163229 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01684595 0,0515666 ! negative regulation of growth GO:0045926 155 84 1,000 0,01777262 0,0543341 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01817268 0,05548665 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 154 87 1,000 0,0189842 0,05789098 GO:0070201|regulation of establishment of protein localization, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01922955 0,05856492 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01922955 0,05849089 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01922955 0,05841703 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01922955 0,05834337 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01922955 0,05826989 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01922955 0,05819659 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01922955 0,05812348 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01922955 0,05805055 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01922955 0,05797781 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01922955 0,05790524 ! meiotic prophase I GO:0007128 13 8 0,000 0,01922955 0,05783286 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01922955 0,05776066 ! oligopeptide transport GO:0006857 15 8 0,000 0,01922955 0,05768864 ! UTP metabolic process GO:0046051 8 8 0,000 0,01922955 0,0576168 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01922955 0,05754514 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01922955 0,05747365 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01922955 0,05740235 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01922955 0,05733121 ! succinate metabolic process GO:0006105 14 8 0,000 0,01922955 0,05726026 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01922955 0,05718948 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01922955 0,05711888 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01922955 0,05704845 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01922955 0,05697819 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01922955 0,05690811 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01922955 0,05683819 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01922955 0,05676845 ! reflex GO:0060004 16 8 0,000 0,01922955 0,05669889 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01922955 0,05662949 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01922955 0,05656026 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01922955 0,0564912 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01922955 0,05642231 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01922955 0,05635358 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01922955 0,05628502 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01922955 0,05621663 ! pigment granule organization GO:0048753 16 8 0,000 0,01922955 0,05614841 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01922955 0,05608035 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01922955 0,05601246 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01922955 0,05594473 ! histidine metabolic process GO:0006547 16 8 0,000 0,01922955 0,05587716 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01922955 0,05580976 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01922955 0,05574252 ! glycine catabolic process GO:0006546 13 8 0,000 0,01922955 0,05567544 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01922955 0,05560852 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01922955 0,05554177 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01922955 0,05547517 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01922955 0,05540873 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01922955 0,05534245 ! melanin metabolic process GO:0006582 15 8 0,000 0,01922955 0,05527633 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01922955 0,05521037 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01922955 0,05514457 ! macrophage activation GO:0042116 12 8 0,000 0,01922955 0,05507892 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01922955 0,05501342 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01922955 0,05494809 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01922955 0,05488291 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01922955 0,05481788 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01922955 0,05475301 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01922955 0,05468829 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01922955 0,05462372 ! osteoblast development GO:0002076 16 8 0,000 0,01922955 0,0545593 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01922955 0,05449504 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01922955 0,05443093 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01922955 0,05436697 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01922955 0,05430316 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01922955 0,0542395 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01922955 0,05417598 ! response to UV-B GO:0010224 16 8 0,000 0,01922955 0,05411262 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01922955 0,0540494 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01922955 0,05398634 ! intermediate filament organization GO:0045109 12 8 0,000 0,01922955 0,05392342 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01922955 0,05386064 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01922955 0,05379801 ! cellular extravasation GO:0045123 12 8 0,000 0,01922955 0,05373553 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01922955 0,05367319 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01922955 0,053611 ! response to antibiotic GO:0046677 11 8 0,000 0,01922955 0,05354895 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01922955 0,05348704 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01922955 0,05342528 ! DNA topological change GO:0006265 12 8 0,000 0,01922955 0,05336366 ! response to tropane GO:0014073 15 8 0,000 0,01922955 0,05330218 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01922955 0,05324084 ! melanosome transport GO:0032402 13 8 0,000 0,01922955 0,05317964 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01922955 0,05311859 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01922955 0,05305767 ! mast cell activation GO:0045576 14 8 0,000 0,01922955 0,0529969 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01922955 0,05293626 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01922955 0,05287576 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01922955 0,0528154 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01922955 0,05275518 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01922955 0,05269509 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01922955 0,05263514 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01922955 0,05257533 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01922955 0,05251565 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01922955 0,05245611 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01922955 0,0523967 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01922955 0,05233743 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01922955 0,05227829 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01922955 0,05221929 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01922955 0,05216042 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01922955 0,05210168 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01922955 0,05204307 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01922955 0,0519846 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01922955 0,05192625 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01922955 0,05186804 ! hormone catabolic process GO:0042447 17 8 0,000 0,01922955 0,05180996 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01922955 0,051752 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01922955 0,05169418 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01922955 0,05163648 ! ATP catabolic process GO:0006200 11 8 0,000 0,01922955 0,05157892 ! blastocyst growth GO:0001832 19 8 0,000 0,01922955 0,05152148 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01922955 0,05146417 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01922955 0,05140699 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01922955 0,05134993 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01922955 0,051293 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01922955 0,0512362 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01922955 0,05117952 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01922955 0,05112297 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01922955 0,05106655 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01922955 0,05101024 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01922955 0,05095406 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01922955 0,05089801 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01922955 0,05084208 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01922955 0,05078627 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01922955 0,05073058 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01922955 0,05067502 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01922955 0,05061957 ! regulation of DNA binding GO:0051101 155 88 1,000 0,01939562 0,05100093 ! gland development GO:0048732 206 88 1,000 0,01939562 0,05094525 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,01981078 0,05197898 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01981078 0,05192236 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,02150847 0,05631053 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02150847 0,05624933 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,02150847 0,05618825 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02160745 0,0563856 ! axon extension GO:0048675 15 9 0,000 0,02160745 0,05632451 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02160745 0,05626355 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02160745 0,05620273 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02160745 0,05614203 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02160745 0,05608147 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02160745 0,05602104 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02160745 0,05596073 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02160745 0,05590056 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02160745 0,05584052 ! phosphate transport GO:0006817 19 9 0,000 0,02160745 0,0557806 ! reproductive behavior GO:0019098 19 9 0,000 0,02160745 0,05572082 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02160745 0,05566116 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02160745 0,05560163 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02160745 0,05554222 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02160745 0,05548295 ! GTP metabolic process GO:0046039 9 9 0,000 0,02160745 0,0554238 ! RNA methylation GO:0001510 15 9 0,000 0,02160745 0,05536477 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02160745 0,05530587 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02160745 0,0552471 ! artery development GO:0060840 24 9 0,000 0,02160745 0,05518845 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02160745 0,05512993 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02160745 0,05507153 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02160745 0,05501325 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02160745 0,0549551 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02160745 0,05489707 ! chemosensory behavior GO:0007635 20 9 0,000 0,02160745 0,05483916 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02160745 0,05478137 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02160745 0,05472371 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02160745 0,05466616 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02160745 0,05460874 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02160745 0,05455144 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02160745 0,05449426 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02160745 0,0544372 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02160745 0,05438025 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02160745 0,05432343 ! protein targeting to ER GO:0045047 22 9 0,000 0,02160745 0,05426672 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02160745 0,05421014 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02160745 0,05415367 ! T cell selection GO:0045058 23 9 0,000 0,02160745 0,05409732 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02160745 0,05404108 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02160745 0,05398497 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02160745 0,05392896 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02160745 0,05387308 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02160745 0,05381731 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02160745 0,05376166 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02160745 0,05370612 ! mannose metabolic process GO:0006013 13 9 0,000 0,02160745 0,05365069 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02160745 0,05359538 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02160745 0,05354019 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02160745 0,0534851 ! receptor clustering GO:0043113 18 9 0,000 0,02160745 0,05343014 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02160745 0,05337528 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02160745 0,05332054 ! ruffle organization GO:0031529 15 9 0,000 0,02160745 0,0532659 ! retinol metabolic process GO:0042572 18 9 0,000 0,02160745 0,05321138 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02160745 0,05315698 ! behavioral fear response GO:0001662 22 9 0,000 0,02160745 0,05310268 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02160745 0,05304849 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02160745 0,05299442 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02160745 0,05294045 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,02160745 0,05288659 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02160745 0,05283285 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02160745 0,05277921 ! segment specification GO:0007379 13 9 0,000 0,02160745 0,05272568 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02160745 0,05267226 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02160745 0,05261895 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02160745 0,05256575 ! response to amine stimulus GO:0014075 13 9 0,000 0,02160745 0,05251265 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02160745 0,05245966 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02160745 0,05240678 ! erythrocyte development GO:0048821 15 9 0,000 0,02160745 0,052354 ! gas homeostasis GO:0033483 16 9 0,000 0,02160745 0,05230133 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02160745 0,05224877 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02160745 0,05219631 ! renal water homeostasis GO:0003091 14 9 0,000 0,02160745 0,05214395 ! postreplication repair GO:0006301 22 9 0,000 0,02160745 0,05209171 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02160745 0,05203956 ! icosanoid secretion GO:0032309 15 9 0,000 0,02160745 0,05198752 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02160745 0,05193559 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02160745 0,05188375 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02160745 0,05183203 ! regulation of cell division GO:0051302 15 9 0,000 0,02160745 0,0517804 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02160745 0,05172888 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02160745 0,05167746 ! sterol catabolic process GO:0016127 11 9 0,000 0,02160745 0,05162614 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02160745 0,05157492 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02160745 0,05152381 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02160745 0,05147279 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02160745 0,05142188 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02160745 0,05137107 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02160745 0,05132036 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02160745 0,05126975 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02160745 0,05121923 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02160745 0,05116882 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02160745 0,05111851 ! purine base metabolic process GO:0006144 21 9 0,000 0,02160745 0,05106829 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02160745 0,05101818 ! pigment granule transport GO:0051904 17 9 0,000 0,02160745 0,05096816 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02160745 0,05091824 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02160745 0,05086842 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02160745 0,05081869 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02160745 0,05076906 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02160745 0,05071953 ! mitochondrion localization GO:0051646 15 9 0,000 0,02160745 0,0506701 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02194206 0,05140466 ! forebrain development GO:0030900 188 95 1,000 0,02237927 0,05237794 ! regulation of protein localization GO:0032880 176 97 1,000 0,02326449 0,05439686 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02397966 0,05601463 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02397966 0,0559603 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02397966 0,05590608 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02397966 0,05585196 ! synapsis GO:0007129 13 10 0,000 0,02397966 0,05579794 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02397966 0,05574403 ! N-glycan processing GO:0006491 20 10 0,000 0,02397966 0,05569022 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02397966 0,05563652 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02397966 0,05558292 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02397966 0,05552942 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02397966 0,05547603 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02397966 0,05542274 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02397966 0,05536955 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02397966 0,05531646 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02397966 0,05526348 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02397966 0,05521059 ! androgen metabolic process GO:0008209 17 10 0,000 0,02397966 0,05515781 ! phospholipid efflux GO:0033700 16 10 0,000 0,02397966 0,05510513 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02397966 0,05505255 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02397966 0,05500007 ! pathogenesis GO:0009405 13 10 0,000 0,02397966 0,05494769 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02397966 0,05489541 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02397966 0,05484322 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02397966 0,05479114 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02397966 0,05473916 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02397966 0,05468727 ! endoderm development GO:0007492 16 10 0,000 0,02397966 0,05463548 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02397966 0,0545838 ! arginine catabolic process GO:0006527 13 10 0,000 0,02397966 0,0545322 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02397966 0,05448071 ! proline metabolic process GO:0006560 13 10 0,000 0,02397966 0,05442931 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02397966 0,05437801 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02397966 0,05432681 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02397966 0,0542757 ! V(D)J recombination GO:0033151 28 10 0,000 0,02397966 0,05422469 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02397966 0,05417378 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02397966 0,05412296 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02397966 0,05407223 ! B cell proliferation GO:0042100 18 10 0,000 0,02397966 0,0540216 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02397966 0,05397107 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02397966 0,05392063 ! multicellular organism growth GO:0035264 18 10 0,000 0,02397966 0,05387028 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02397966 0,05382003 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02397966 0,05376987 ! epithelial cell development GO:0002064 20 10 0,000 0,02397966 0,05371981 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02397966 0,05366983 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02397966 0,05361996 ! macroautophagy GO:0016236 17 10 0,000 0,02397966 0,05357017 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02397966 0,05352047 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02397966 0,05347087 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02397966 0,05342136 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02397966 0,05337194 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02397966 0,05332262 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02397966 0,05327338 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02397966 0,05322424 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02397966 0,05317518 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02397966 0,05312622 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02397966 0,05307734 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02397966 0,05302856 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02397966 0,05297986 ! response to dsRNA GO:0043331 20 10 0,000 0,02397966 0,05293126 ! DNA ligation GO:0006266 19 10 0,000 0,02397966 0,05288274 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02397966 0,05283431 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02397966 0,05278598 ! melanosome localization GO:0032400 16 10 0,000 0,02397966 0,05273773 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02397966 0,05268956 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02397966 0,05264149 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02397966 0,0525935 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02397966 0,0525456 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02397966 0,05249779 ! mRNA cleavage GO:0006379 17 10 0,000 0,02397966 0,05245007 ! protein sumoylation GO:0016925 15 10 0,000 0,02397966 0,05240243 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02397966 0,05235487 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02397966 0,05230741 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02397966 0,05226003 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02397966 0,05221273 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02397966 0,05216553 ! salivary gland development GO:0007431 27 10 0,000 0,02397966 0,0521184 ! prophase GO:0051324 15 10 0,000 0,02397966 0,05207136 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02397966 0,05202441 ! apical protein localization GO:0045176 15 10 0,000 0,02397966 0,05197754 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02397966 0,05193076 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02397966 0,05188406 ! midbrain development GO:0030901 13 10 0,000 0,02397966 0,05183744 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02397966 0,05179091 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02397966 0,05174446 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02397966 0,05169809 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02397966 0,05165181 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02397966 0,05160561 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02397966 0,05155949 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02397966 0,05151346 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02397966 0,0514675 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02397966 0,05142163 ! oocyte development GO:0048599 17 10 0,000 0,02397966 0,05137584 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02397966 0,05133014 ! blastocyst formation GO:0001825 17 10 0,000 0,02397966 0,05128451 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02397966 0,05123896 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02397966 0,0511935 ! activation of innate immune response GO:0002218 12 10 0,000 0,02397966 0,05114811 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02397966 0,05110281 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02397966 0,05105759 ! response to nicotine GO:0035094 20 10 0,000 0,02397966 0,05101244 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02397966 0,05096738 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02397966 0,05092239 ! cell cycle arrest GO:0007050 213 100 1,000 0,02461903 0,05223404 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02634621 0,05584931 ! respiratory burst GO:0045730 17 11 0,000 0,02634621 0,05580015 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02634621 0,05575107 ! neuron fate specification GO:0048665 17 11 0,000 0,02634621 0,05570208 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02634621 0,05565318 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02634621 0,05560436 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02634621 0,05555563 ! thyroid gland development GO:0030878 26 11 0,000 0,02634621 0,05550698 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02634621 0,05545842 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02634621 0,05540994 ! response to pain GO:0048265 24 11 0,000 0,02634621 0,05536155 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02634621 0,05531324 ! T cell proliferation GO:0042098 26 11 0,000 0,02634621 0,05526501 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02634621 0,05521687 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02634621 0,05516882 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02634621 0,05512085 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02634621 0,05507296 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02634621 0,05502515 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02634621 0,05497743 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02634621 0,05492979 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02634621 0,05488223 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02634621 0,05483475 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02634621 0,05478736 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02634621 0,05474005 ! lipid digestion GO:0044241 18 11 0,000 0,02634621 0,05469281 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02634621 0,05464567 ! UV protection GO:0009650 19 11 0,000 0,02634621 0,0545986 ! adult heart development GO:0007512 14 11 0,000 0,02634621 0,05455161 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02634621 0,05450471 ! temperature homeostasis GO:0001659 17 11 0,000 0,02634621 0,05445788 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02634621 0,05441113 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02634621 0,05436447 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02634621 0,05431789 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02634621 0,05427138 ! regulation of organ growth GO:0046620 13 11 0,000 0,02634621 0,05422495 ! pigment granule localization GO:0051875 20 11 0,000 0,02634621 0,05417861 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02634621 0,05413234 ! vasoconstriction GO:0042310 18 11 0,000 0,02634621 0,05408615 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02634621 0,05404004 ! embryonic axis specification GO:0000578 18 11 0,000 0,02634621 0,05399401 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02634621 0,05394806 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02634621 0,05390219 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02634621 0,05385639 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02634621 0,05381067 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02634621 0,05376503 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02634621 0,05371947 ! zymogen activation GO:0031638 15 11 0,000 0,02634621 0,05367398 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02634621 0,05362857 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02634621 0,05358324 ! nucleosome positioning GO:0016584 15 11 0,000 0,02634621 0,05353798 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02634621 0,0534928 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02634621 0,0534477 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02634621 0,05340267 ! acid secretion GO:0046717 18 11 0,000 0,02634621 0,05335772 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02634621 0,05331284 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02634621 0,05326804 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02634621 0,05322332 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02634621 0,05317867 ! oocyte differentiation GO:0009994 18 11 0,000 0,02634621 0,05313409 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02634621 0,05308959 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02634621 0,05304517 ! cholesterol efflux GO:0033344 19 11 0,000 0,02634621 0,05300081 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02634621 0,05295653 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02634621 0,05291233 ! germ cell migration GO:0008354 25 11 0,000 0,02634621 0,0528682 ! embryonic gut development GO:0048566 15 11 0,000 0,02634621 0,05282414 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02634621 0,05278016 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02634621 0,05273625 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02634621 0,05269241 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02634621 0,05264865 ! defense response to fungus GO:0050832 13 11 0,000 0,02634621 0,05260496 ! developmental induction GO:0031128 19 11 0,000 0,02634621 0,05256134 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02634621 0,05251779 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02634621 0,05247431 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02634621 0,05243091 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02634621 0,05238758 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02634621 0,05234432 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02634621 0,05230113 ! nucleus localization GO:0051647 19 11 0,000 0,02634621 0,05225801 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02634621 0,05221497 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02870709 0,05684712 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02870709 0,05680037 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02870709 0,0567537 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02870709 0,05670711 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02870709 0,05666059 ! virus-host interaction GO:0019048 29 12 0,000 0,02870709 0,05661414 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02870709 0,05656778 ! mating GO:0007618 17 12 0,000 0,02870709 0,05652149 ! protein complex disassembly GO:0043241 27 12 0,000 0,02870709 0,05647527 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02870709 0,05642913 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02870709 0,05638307 ! hippocampus development GO:0021766 26 12 0,000 0,02870709 0,05633708 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02870709 0,05629116 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02870709 0,05624532 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02870709 0,05619956 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02870709 0,05615387 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02870709 0,05610825 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02870709 0,05606271 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02870709 0,05601724 ! drug transport GO:0015893 16 12 0,000 0,02870709 0,05597184 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02870709 0,05592652 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02870709 0,05588127 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02870709 0,0558361 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02870709 0,055791 ! focal adhesion formation GO:0048041 35 12 0,000 0,02870709 0,05574597 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02870709 0,05570101 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02870709 0,05565613 ! forebrain cell migration GO:0021885 21 12 0,000 0,02870709 0,05561132 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02870709 0,05556658 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02870709 0,05552191 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02870709 0,05547731 ! entry into host cell GO:0030260 32 12 0,000 0,02870709 0,05543279 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02870709 0,05538834 ! monoamine transport GO:0015844 18 12 0,000 0,02870709 0,05534395 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02870709 0,05529964 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02870709 0,0552554 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02870709 0,05521124 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02870709 0,05516714 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02870709 0,05512311 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02870709 0,05507915 ! protein homotetramerization GO:0051289 21 12 0,000 0,02870709 0,05503526 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02870709 0,05499145 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02870709 0,0549477 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02870709 0,05490402 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02870709 0,05486041 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02870709 0,05481687 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02870709 0,0547734 ! cranial nerve development GO:0021545 20 12 0,000 0,02870709 0,05473 ! fucose catabolic process GO:0019317 22 12 0,000 0,02870709 0,05468666 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02870709 0,0546434 ! histone methylation GO:0016571 26 12 0,000 0,02870709 0,0546002 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02870709 0,05455707 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02870709 0,05451401 ! gland morphogenesis GO:0022612 29 12 0,000 0,02870709 0,05447102 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02870709 0,0544281 ! T cell homeostasis GO:0043029 25 12 0,000 0,02870709 0,05438524 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02870709 0,05434245 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02870709 0,05429973 ! spleen development GO:0048536 22 12 0,000 0,02870709 0,05425707 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02870709 0,05421449 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02870709 0,05417196 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02870709 0,05412951 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02870709 0,05408712 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02870709 0,0540448 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02870709 0,05400255 ! response to cold GO:0009409 17 12 0,000 0,02870709 0,05396036 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02870709 0,05391823 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02870709 0,05387617 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03106232 0,05825094 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03106232 0,05820557 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03106232 0,05816028 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03106232 0,05811505 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03106232 0,05806989 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03106232 0,05802481 ! lipid localization GO:0010876 28 13 0,000 0,03106232 0,05797979 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03106232 0,05793485 ! organelle fusion GO:0048284 32 13 0,000 0,03106232 0,05788997 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03106232 0,05784517 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03106232 0,05780043 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03106232 0,05775576 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03106232 0,05771116 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03106232 0,05766663 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03106232 0,05762217 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03106232 0,05757778 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03106232 0,05753345 ! methionine metabolic process GO:0006555 27 13 0,000 0,03106232 0,05748919 ! plasma membrane organization GO:0007009 24 13 0,000 0,03106232 0,05744501 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03106232 0,05740089 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03106232 0,05735683 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03106232 0,05731285 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03106232 0,05726893 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03106232 0,05722508 ! response to X-ray GO:0010165 25 13 0,000 0,03106232 0,0571813 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03106232 0,05713758 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03106232 0,05709393 ! exocrine system development GO:0035272 32 13 0,000 0,03106232 0,05705035 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,03106232 0,05700683 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03106232 0,05696338 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03106232 0,05691999 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03106232 0,05687668 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03106232 0,05683342 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03106232 0,05679024 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03106232 0,05674712 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03106232 0,05670406 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03106232 0,05666107 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03106232 0,05661815 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03106232 0,05657529 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03106232 0,05653249 ! ribosome assembly GO:0042255 17 13 0,000 0,03106232 0,05648976 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03106232 0,05644709 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03106232 0,05640449 ! chromatin silencing GO:0006342 26 13 0,000 0,03106232 0,05636196 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03106232 0,05631948 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03106232 0,05627707 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03106232 0,05623473 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03106232 0,05619245 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03106232 0,05615023 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03106232 0,05610807 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03106232 0,05606598 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03106232 0,05602395 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03106232 0,05598199 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03106232 0,05594008 ! embryonic placenta development GO:0001892 23 13 0,000 0,03106232 0,05589824 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03106232 0,05585647 ! insulin secretion GO:0030073 23 13 0,000 0,03106232 0,05581475 ! actin filament polymerization GO:0030041 24 13 0,000 0,03106232 0,0557731 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03106232 0,05573151 ! acrosome reaction GO:0007340 18 13 0,000 0,03106232 0,05568998 ! rRNA transcription GO:0009303 25 14 0,000 0,03341193 0,05985785 ! lactation GO:0007595 26 14 0,000 0,03341193 0,05981332 ! reproductive cellular process GO:0048610 20 14 0,000 0,03341193 0,05976885 ! tRNA modification GO:0006400 20 14 0,000 0,03341193 0,05972444 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03341193 0,0596801 ! regulation of S phase GO:0033261 23 14 0,000 0,03341193 0,05963583 ! water transport GO:0006833 21 14 0,000 0,03341193 0,05959162 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03341193 0,05954748 ! non-recombinational repair GO:0000726 25 14 0,000 0,03341193 0,0595034 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03341193 0,05945939 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03341193 0,05941545 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03341193 0,05937156 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03341193 0,05932775 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03341193 0,059284 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03341193 0,05924031 ! palate development GO:0060021 31 14 0,000 0,03341193 0,05919669 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03341193 0,05915313 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03341193 0,05910963 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03341193 0,0590662 ! arginine metabolic process GO:0006525 17 14 0,000 0,03341193 0,05902283 ! regulation of heart rate GO:0002027 24 14 0,000 0,03341193 0,05897953 ! organic alcohol transport GO:0015850 29 14 0,000 0,03341193 0,05893629 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03341193 0,05889311 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03341193 0,05885 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03341193 0,05880695 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03341193 0,05876396 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03341193 0,05872104 ! L-amino acid transport GO:0015807 30 14 0,000 0,03341193 0,05867817 ! bone mineralization GO:0030282 17 14 0,000 0,03341193 0,05863537 ! stem cell development GO:0048864 43 14 0,000 0,03341193 0,05859264 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03341193 0,05854996 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03341193 0,05850735 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03341193 0,0584648 ! cerebellum development GO:0021549 21 14 0,000 0,03341193 0,05842231 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03341193 0,05837988 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03341193 0,05833752 ! response to gamma radiation GO:0010332 28 14 0,000 0,03341193 0,05829521 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03341193 0,05825297 ! cofactor transport GO:0051181 26 14 0,000 0,03341193 0,05821079 ! NADP metabolic process GO:0006739 24 14 0,000 0,03341193 0,05816867 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03341193 0,05812661 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03341193 0,05808461 ! intestinal absorption GO:0050892 25 14 0,000 0,03341193 0,05804267 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03341193 0,05800079 ! oxygen transport GO:0015671 21 14 0,000 0,03341193 0,05795898 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03341193 0,05791722 ! male genitalia development GO:0030539 24 14 0,000 0,03341193 0,05787552 ! regulation of axon extension GO:0030516 37 14 0,000 0,03341193 0,05783388 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03341193 0,05779231 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03341193 0,05775079 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03575591 0,06175788 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03575591 0,06171357 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03575591 0,06166933 ! superoxide anion generation GO:0042554 20 15 0,000 0,03575591 0,06162516 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03575591 0,06158105 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03575591 0,061537 ! copper ion transport GO:0006825 20 15 0,000 0,03575591 0,06149301 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03575591 0,06144909 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03575591 0,06140523 ! sulfate transport GO:0008272 23 15 0,000 0,03575591 0,06136143 ! response to cAMP GO:0051591 22 15 0,000 0,03575591 0,06131769 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03575591 0,06127402 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03575591 0,06123041 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03575591 0,06118686 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03575591 0,06114337 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03575591 0,06109994 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03575591 0,06105658 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03575591 0,06101328 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03575591 0,06097004 ! pituitary gland development GO:0021983 29 15 0,000 0,03575591 0,06092686 ! vesicle coating GO:0006901 33 15 0,000 0,03575591 0,06088374 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03575591 0,06084068 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03575591 0,06079768 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03575591 0,06075475 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03575591 0,06071187 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03575591 0,06066906 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03575591 0,0606263 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03575591 0,06058361 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03575591 0,06054097 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03575591 0,0604984 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03575591 0,06045588 ! tissue regeneration GO:0042246 26 15 0,000 0,03575591 0,06041343 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03575591 0,06037103 ! water homeostasis GO:0030104 27 15 0,000 0,03575591 0,0603287 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03575591 0,06028642 ! muscle maintenance GO:0046716 26 15 0,000 0,03575591 0,0602442 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03575591 0,06020204 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03575591 0,06015995 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03575591 0,06011791 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03575591 0,06007592 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03575591 0,060034 ! cell killing GO:0001906 29 15 0,000 0,03575591 0,05999214 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03575591 0,05995033 ! detection of bacterium GO:0016045 18 15 0,000 0,03575591 0,05990858 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03575591 0,05986689 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03575591 0,05982526 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03575591 0,05978368 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03575591 0,05974217 ! peptide hormone processing GO:0016486 23 15 0,000 0,03575591 0,05970071 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03809429 0,06356093 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03809429 0,06351688 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03809429 0,06347289 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03809429 0,06342897 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03809429 0,0633851 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03809429 0,0633413 ! bone remodeling GO:0046849 27 16 0,000 0,03809429 0,06329755 ! filopodium assembly GO:0046847 32 16 0,000 0,03809429 0,06325387 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03809429 0,06321025 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03809429 0,06316668 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03809429 0,06312318 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03809429 0,06307974 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03809429 0,06303635 ! startle response GO:0001964 28 16 0,000 0,03809429 0,06299303 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03809429 0,06294976 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03809429 0,06290656 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03809429 0,06286341 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03809429 0,06282033 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03809429 0,0627773 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03809429 0,06273433 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03809429 0,06269142 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03809429 0,06264857 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03809429 0,06260578 ! response to osmotic stress GO:0006970 25 16 0,000 0,03809429 0,06256304 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03809429 0,06252037 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03809429 0,06247775 ! fructose metabolic process GO:0006000 25 16 0,000 0,03809429 0,06243519 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03809429 0,06239269 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03809429 0,06235024 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03809429 0,06230786 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03809429 0,06226553 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03809429 0,06222326 ! axon cargo transport GO:0008088 43 16 0,000 0,03809429 0,06218104 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03809429 0,06213889 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03809429 0,06209679 ! DNA replication initiation GO:0006270 27 16 0,000 0,03809429 0,06205474 ! neuron recognition GO:0008038 35 16 0,000 0,03809429 0,06201276 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03809429 0,06197083 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03809429 0,06192896 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03809429 0,06188714 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03809429 0,06184538 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03809429 0,06180368 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03809429 0,06176203 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03809429 0,06172044 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03809429 0,06167891 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03809429 0,06163743 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03809429 0,06159601 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03809429 0,06155464 ! defense response to virus GO:0051607 37 16 0,000 0,03809429 0,06151333 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04042707 0,06523644 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04042707 0,06519272 ! metencephalon development GO:0022037 30 17 0,000 0,04042707 0,06514905 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04042707 0,06510544 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04042707 0,0650619 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04042707 0,06501841 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04042707 0,06497497 ! signal complex assembly GO:0007172 41 17 0,000 0,04042707 0,0649316 ! endothelial cell migration GO:0043542 28 17 0,000 0,04042707 0,06488828 ! inositol metabolic process GO:0006020 28 17 0,000 0,04042707 0,06484502 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04042707 0,06480182 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04042707 0,06475868 ! glial cell development GO:0021782 27 17 0,000 0,04042707 0,06471559 ! limbic system development GO:0021761 36 17 0,000 0,04042707 0,06467256 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04042707 0,06462959 ! adult walking behavior GO:0007628 33 17 0,000 0,04042707 0,06458668 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04042707 0,06454382 ! heart looping GO:0001947 30 17 0,000 0,04042707 0,06450102 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04042707 0,06445827 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04042707 0,06441559 ! myoblast differentiation GO:0045445 45 17 0,000 0,04042707 0,06437295 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04042707 0,06433038 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04042707 0,06428786 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04042707 0,0642454 ! glycine metabolic process GO:0006544 28 17 0,000 0,04042707 0,06420299 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04042707 0,06416064 ! NAD metabolic process GO:0019674 29 17 0,000 0,04042707 0,06411835 ! membrane budding GO:0006900 37 17 0,000 0,04042707 0,06407611 ! DNA integration GO:0015074 29 17 0,000 0,04042707 0,06403393 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04042707 0,0639918 ! regulation of protein binding GO:0043393 33 17 0,000 0,04042707 0,06394973 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04042707 0,06390771 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04042707 0,06386575 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04042707 0,06382384 ! genitalia development GO:0048806 30 17 0,000 0,04042707 0,06378199 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04042707 0,06374019 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04042707 0,06369845 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04042707 0,06365676 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04042707 0,06361513 ! steroid catabolic process GO:0006706 31 17 0,000 0,04042707 0,06357355 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04042707 0,06353203 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04042707 0,06349056 ! gas transport GO:0015669 25 17 0,000 0,04042707 0,06344914 ! organic cation transport GO:0015695 31 17 0,000 0,04042707 0,06340778 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04042707 0,06336647 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04042707 0,06332522 ! microspike assembly GO:0030035 36 17 0,000 0,04042707 0,06328402 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04042707 0,06324287 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04042707 0,06320178 ! neuron maturation GO:0042551 42 18 0,000 0,04275427 0,06679661 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04275427 0,06675327 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04275427 0,06670998 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04275427 0,06666674 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04275427 0,06662357 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04275427 0,06658044 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04275427 0,06653738 ! memory GO:0007613 31 18 0,000 0,04275427 0,06649437 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04275427 0,06645141 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04275427 0,06640851 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04275427 0,06636567 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04275427 0,06632288 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04275427 0,06628015 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04275427 0,06623747 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04275427 0,06619484 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04275427 0,06615227 ! response to retinoic acid GO:0032526 26 18 0,000 0,04275427 0,06610976 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04275427 0,0660673 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04275427 0,06602489 ! response to fungus GO:0009620 21 18 0,000 0,04275427 0,06598254 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04275427 0,06594025 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04275427 0,065898 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04275427 0,06585582 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04275427 0,06581368 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04275427 0,0657716 ! vitamin transport GO:0051180 27 18 0,000 0,04275427 0,06572958 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04275427 0,0656876 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04275427 0,06564568 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04275427 0,06560382 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04275427 0,065562 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,04275427 0,06552025 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04275427 0,06547854 ! nerve development GO:0021675 28 18 0,000 0,04275427 0,06543689 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04275427 0,06539529 ! protein secretion GO:0009306 39 19 0,000 0,04507591 0,06890257 ! positive regulation of translation GO:0045727 30 19 0,000 0,04507591 0,06885882 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04507591 0,06881513 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04507591 0,06877149 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04507591 0,06872791 ! skin development GO:0043588 36 19 0,000 0,04507591 0,06868438 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04507591 0,06864091 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04507591 0,0685975 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04507591 0,06855414 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04507591 0,06851083 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04507591 0,06846758 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04507591 0,06842438 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04507591 0,06838124 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04507591 0,06833815 ! cerebral cortex development GO:0021987 36 19 0,000 0,04507591 0,06829512 ! pigmentation during development GO:0048066 41 19 0,000 0,04507591 0,06825214 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04507591 0,06820921 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04507591 0,06816634 ! heme metabolic process GO:0042168 36 19 0,000 0,04507591 0,06812352 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04507591 0,06808076 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04507591 0,06803804 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04507591 0,06799539 ! peptide cross-linking GO:0018149 37 19 0,000 0,04507591 0,06795278 ! protein export from nucleus GO:0006611 36 19 0,000 0,04507591 0,06791023 ! heart process GO:0003015 30 19 0,000 0,04507591 0,06786774 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04507591 0,06782529 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04507591 0,0677829 ! visual learning GO:0008542 36 19 0,000 0,04507591 0,06774056 ! cellular pigmentation GO:0033059 36 19 0,000 0,04507591 0,06769828 ! G1 phase GO:0051318 40 19 0,000 0,04507591 0,06765605 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04507591 0,06761387 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04507591 0,06757174 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04507591 0,06752967 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04507591 0,06748764 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04507591 0,06744567 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04507591 0,06740376 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04507591 0,06736189 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04507591 0,06732008 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04507591 0,06727831 ! cilium assembly GO:0042384 37 19 0,000 0,04507591 0,0672366 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04507591 0,06719495 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04739199 0,0706038 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04739199 0,07056011 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04739199 0,07051647 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04739199 0,07047289 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04739199 0,07042936 ! response to vitamin GO:0033273 31 20 0,000 0,04739199 0,07038589 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04739199 0,07034247 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04739199 0,0702991 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04739199 0,07025578 ! response to alkaloid GO:0043279 38 20 0,000 0,04739199 0,07021252 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04739199 0,07016932 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04739199 0,07012616 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04739199 0,07008306 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04739199 0,07004001 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04739199 0,06999702 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04739199 0,06995407 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04739199 0,06991118 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04739199 0,06986834 ! body fluid secretion GO:0007589 31 20 0,000 0,04739199 0,06982556 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04739199 0,06978283 ! peptide secretion GO:0002790 35 20 0,000 0,04739199 0,06974015 ! stem cell differentiation GO:0048863 53 20 0,000 0,04739199 0,06969752 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04739199 0,06965494 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04739199 0,06961242 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04739199 0,06956994 ! sensory perception of pain GO:0019233 30 20 0,000 0,04739199 0,06952752 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04739199 0,06948515 ! diencephalon development GO:0021536 34 20 0,000 0,04739199 0,06944284 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04739199 0,06940057 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04739199 0,06935836 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04739199 0,06931619 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04739199 0,06927408 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04739199 0,06923202 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04739199 0,06919001 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04739199 0,06914805 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04739199 0,06910614 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04739199 0,06906429 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04739199 0,06902248 ! actin filament-based movement GO:0030048 43 20 0,000 0,04739199 0,06898072 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04739199 0,06893902 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04739199 0,06889736 ! negative regulation of translation GO:0017148 29 20 0,000 0,04739199 0,06885576 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04739199 0,06881421 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04739199 0,0687727 ! regulation of cell killing GO:0031341 42 21 0,000 0,04970254 0,07208216 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04970254 0,07203874 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04970254 0,07199537 ! hormone secretion GO:0046879 38 21 0,000 0,04970254 0,07195205 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04970254 0,07190878 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04970254 0,07186557 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04970254 0,0718224 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04970254 0,07177929 ! axis specification GO:0009798 38 21 0,000 0,04970254 0,07173623 ! ovarian follicle development GO:0001541 35 21 0,000 0,04970254 0,07169323 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04970254 0,07165027 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04970254 0,07160737 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04970254 0,07156451 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04970254 0,07152171 ! cell aging GO:0007569 44 21 0,000 0,04970254 0,07147896 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04970254 0,07143626 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04970254 0,07139361 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04970254 0,07135102 ! cytolysis GO:0019835 24 21 0,000 0,04970254 0,07130847 ! vasodilation GO:0042311 39 21 0,000 0,04970254 0,07126597 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04970254 0,07122353 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04970254 0,07118113 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04970254 0,07113879 ! oogenesis GO:0048477 36 21 0,000 0,04970254 0,07109649 ! DNA modification GO:0006304 34 21 0,000 0,04970254 0,07105425 ! collagen fibril organization GO:0030199 59 21 0,000 0,04970254 0,07101206 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04970254 0,07096991 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04970254 0,07092782 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04970254 0,07088577 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04970254 0,07084378 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04970254 0,07080184 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04970254 0,07075994 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04970254 0,0707181 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04970254 0,0706763 ! collagen catabolic process GO:0030574 28 21 0,000 0,04970254 0,07063456 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04970254 0,07059286 ! gut development GO:0048565 39 21 0,000 0,04970254 0,07055121 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05200755 0,07377958 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05200755 0,0737361 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05200755 0,07369268 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05200755 0,0736493 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05200755 0,07360598 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05200755 0,07356271 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05200755 0,07351949 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05200755 0,07347632 ! regeneration GO:0031099 41 22 0,000 0,05200755 0,0734332 ! keratinization GO:0031424 28 22 0,000 0,05200755 0,07339013 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05200755 0,07334711 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05200755 0,07330414 ! sensory perception of taste GO:0050909 28 22 0,000 0,05200755 0,07326122 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05200755 0,07321835 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05200755 0,07317554 ! vacuolar transport GO:0007034 36 22 0,000 0,05200755 0,07313277 ! lysosome organization GO:0007040 41 22 0,000 0,05200755 0,07309005 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05200755 0,07304738 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05200755 0,07300476 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05200755 0,0729622 ! fucose metabolic process GO:0006004 39 22 0,000 0,05200755 0,07291968 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05200755 0,07287721 ! ureteric bud development GO:0001657 43 22 0,000 0,05200755 0,07283479 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05200755 0,07279242 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05200755 0,0727501 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05200755 0,07270783 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05200755 0,0726656 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05200755 0,07262343 ! sarcomere organization GO:0045214 30 22 0,000 0,05200755 0,0725813 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05200755 0,07253923 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05200755 0,0724972 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05200755 0,07245522 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05200755 0,07241329 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05200755 0,07237141 ! protein stabilization GO:0050821 39 22 0,000 0,05200755 0,07232958 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,05430705 0,07548398 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05430705 0,07544039 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05430705 0,07539686 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05430705 0,07535338 ! gluconeogenesis GO:0006094 33 23 0,000 0,05430705 0,07530995 ! viral genome replication GO:0019079 41 23 0,000 0,05430705 0,07526657 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05430705 0,07522324 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05430705 0,07517996 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05430705 0,07513672 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05430705 0,07509354 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05430705 0,07505041 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05430705 0,07500733 ! visual behavior GO:0007632 42 23 0,000 0,05430705 0,07496429 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05430705 0,07492131 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05430705 0,07487837 ! response to ethanol GO:0045471 46 23 0,000 0,05430705 0,07483549 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05430705 0,07479265 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05430705 0,07474986 ! peroxisome organization GO:0007031 37 23 0,000 0,05430705 0,07470713 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05430705 0,07466444 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05430705 0,0746218 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05430705 0,0745792 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05430705 0,07453666 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05430705 0,07449416 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05430705 0,07445172 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05430705 0,07440932 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05430705 0,07436697 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05430705 0,07432467 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05430705 0,07428241 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05430705 0,07424021 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05430705 0,07419805 ! fatty acid transport GO:0015908 44 23 0,000 0,05430705 0,07415594 ! platelet activation GO:0030168 37 23 0,000 0,05430705 0,07411388 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05430705 0,07407186 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05430705 0,07402989 ! hormone transport GO:0009914 40 23 0,000 0,05430705 0,07398797 ! cell-cell recognition GO:0009988 25 23 0,000 0,05430705 0,0739461 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05430705 0,07390428 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05430705 0,0738625 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05430705 0,07382077 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05430705 0,07377909 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05430705 0,07373745 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05660105 0,07680887 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05660105 0,07676557 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05660105 0,07672232 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05660105 0,07667912 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05660105 0,07663597 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05660105 0,07659287 ! vacuole organization GO:0007033 43 24 0,000 0,05660105 0,07654982 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05660105 0,07650681 ! digestive system process GO:0022600 39 24 0,000 0,05660105 0,07646385 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05660105 0,07642094 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05660105 0,07637808 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05660105 0,07633527 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05660105 0,07629251 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05660105 0,07624979 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05660105 0,07620712 ! membrane depolarization GO:0051899 39 24 0,000 0,05660105 0,0761645 ! pallium development GO:0021543 49 24 0,000 0,05660105 0,07612192 ! pentose metabolic process GO:0019321 35 24 0,000 0,05660105 0,0760794 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05660105 0,07603692 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05660105 0,07599449 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05660105 0,0759521 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05660105 0,07590977 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05660105 0,07586748 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05660105 0,07582524 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05660105 0,07578304 ! regulation of amine transport GO:0051952 40 24 0,000 0,05660105 0,07574089 ! protein tetramerization GO:0051262 52 24 0,000 0,05660105 0,07569879 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05888956 0,07871571 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05888956 0,078672 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05888956 0,07862835 ! phototransduction GO:0007602 33 25 0,000 0,05888956 0,07858474 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05888956 0,07854117 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05888956 0,07849766 ! sperm motility GO:0030317 31 25 0,000 0,05888956 0,0784542 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05888956 0,07841078 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05888956 0,07836741 ! receptor metabolic process GO:0043112 46 25 0,000 0,05888956 0,07832409 ! chromosome condensation GO:0030261 45 25 0,000 0,05888956 0,07828082 ! response to starvation GO:0042594 42 25 0,000 0,05888956 0,07823759 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05888956 0,07819441 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,05888956 0,07815128 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05888956 0,0781082 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05888956 0,07806517 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05888956 0,07802218 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05888956 0,07797924 ! interaction with host GO:0051701 62 25 0,000 0,05888956 0,07793635 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05888956 0,0778935 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05888956 0,0778507 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05888956 0,07780795 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05888956 0,07776525 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05888956 0,07772259 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05888956 0,07767998 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05888956 0,07763741 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05888956 0,07759489 ! telomere organization GO:0032200 43 25 0,000 0,05888956 0,07755242 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05888956 0,07751 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05888956 0,07746762 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06117259 0,08042692 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06117259 0,08038299 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06117259 0,08033911 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06117259 0,08029529 ! initiation of viral infection GO:0019059 57 26 0,000 0,06117259 0,0802515 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06117259 0,08020777 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06117259 0,08016408 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06117259 0,08012045 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06117259 0,08007685 ! molting cycle process GO:0022404 50 26 0,000 0,06117259 0,08003331 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06117259 0,07998981 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06117259 0,07994637 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06117259 0,07990296 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06117259 0,07985961 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,06117259 0,0798163 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,06117259 0,07977304 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06117259 0,07972983 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06117259 0,07968666 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06117259 0,07964354 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06117259 0,07960046 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06117259 0,07955744 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06117259 0,07951446 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06117259 0,07947152 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06117259 0,07942863 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06117259 0,07938579 ! blastocyst development GO:0001824 49 26 0,000 0,06117259 0,079343 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06117259 0,07930025 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06117259 0,07925754 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06117259 0,07921489 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06345016 0,08212001 ! iron ion transport GO:0006826 59 27 0,000 0,06345016 0,08207586 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06345016 0,08203175 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06345016 0,0819877 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06345016 0,08194369 ! fat cell differentiation GO:0045444 50 27 0,000 0,06345016 0,08189973 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06345016 0,08185581 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,06345016 0,08181195 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06345016 0,08176813 ! autophagy GO:0006914 41 27 0,000 0,06345016 0,08172435 ! male gonad development GO:0008584 44 27 0,000 0,06345016 0,08168063 ! response to toxin GO:0009636 47 27 0,000 0,06345016 0,08163695 ! primary neural tube formation GO:0014020 51 27 0,000 0,06345016 0,08159332 ! base-excision repair GO:0006284 41 27 0,000 0,06345016 0,08154973 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06345016 0,08150619 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06345016 0,0814627 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06345016 0,08141925 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06345016 0,08137585 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06345016 0,0813325 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06345016 0,08128919 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06572229 0,08415531 ! circadian rhythm GO:0007623 50 28 0,000 0,06572229 0,08411054 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06572229 0,08406583 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06572229 0,08402116 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06572229 0,08397654 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,06572229 0,08393196 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06572229 0,08388744 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06572229 0,08384296 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06572229 0,08379853 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06572229 0,08375414 ! synaptogenesis GO:0007416 42 28 0,000 0,06572229 0,0837098 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,06572229 0,08366551 ! lipid oxidation GO:0034440 43 28 0,000 0,06572229 0,08362127 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06572229 0,08357707 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06572229 0,08353292 ! translational initiation GO:0006413 65 29 0,000 0,06798897 0,08636825 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06798897 0,08632267 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06798897 0,08627714 ! regulation of pH GO:0006885 43 29 0,000 0,06798897 0,08623166 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06798897 0,08618623 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06798897 0,08614084 ! catechol metabolic process GO:0009712 54 29 0,000 0,06798897 0,08609551 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06798897 0,08605022 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06798897 0,08600498 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06798897 0,08595978 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06798897 0,08591463 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06798897 0,08586953 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06798897 0,08582448 ! cell fate determination GO:0001709 60 29 0,000 0,06798897 0,08577948 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06798897 0,08573452 ! detection of light stimulus GO:0009583 38 29 0,000 0,06798897 0,08568961 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,06798897 0,08564474 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06798897 0,08559993 ! tissue homeostasis GO:0001894 48 29 0,000 0,06798897 0,08555516 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,06798897 0,08551044 ! phenol metabolic process GO:0018958 55 30 0,000 0,07025023 0,08830828 ! zinc ion transport GO:0006829 45 30 0,000 0,07025023 0,08826217 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07025023 0,0882161 ! cell junction assembly GO:0034329 78 30 0,000 0,07025023 0,08817009 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07025023 0,08812412 ! acute-phase response GO:0006953 49 30 0,000 0,07025023 0,08807819 ! myofibril assembly GO:0030239 47 30 0,000 0,07025023 0,08803232 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07025023 0,08798649 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07025023 0,08794072 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07025023 0,08789498 ! phospholipid transport GO:0015914 51 30 0,000 0,07025023 0,0878493 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07025023 0,08780367 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07025023 0,08775808 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07025023 0,08771254 ! eye morphogenesis GO:0048592 60 30 0,000 0,07025023 0,08766704 ! response to heat GO:0009408 50 30 0,000 0,07025023 0,08762159 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07250608 0,09038841 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07250608 0,0903416 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07250608 0,09029484 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07250608 0,09024813 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07250608 0,09020146 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07250608 0,09015485 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07250608 0,09010828 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07250608 0,09006176 ! ovulation cycle process GO:0022602 49 31 0,000 0,07250608 0,09001529 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07250608 0,08996886 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07250608 0,08992249 ! peptide transport GO:0015833 55 31 0,000 0,07250608 0,08987616 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07250608 0,08982988 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07250608 0,08978365 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07250608 0,08973746 ! mesoderm formation GO:0001707 69 31 0,000 0,07250608 0,08969133 ! natural killer cell activation GO:0030101 45 31 0,000 0,07250608 0,08964524 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07250608 0,08959919 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07250608 0,0895532 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07250608 0,08950725 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,07250608 0,08946135 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07250608 0,08941549 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07475653 0,09214355 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07475653 0,09209637 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07475653 0,09204924 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07475653 0,09200215 ! cholesterol transport GO:0030301 56 32 0,000 0,07475653 0,09195512 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07475653 0,09190813 ! spliceosome assembly GO:0000245 67 32 0,000 0,07475653 0,09186119 ! spindle organization GO:0007051 46 32 0,000 0,07475653 0,0918143 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07475653 0,09176746 ! metanephros development GO:0001656 74 32 0,000 0,07475653 0,09172066 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07475653 0,09167391 ! response to ionizing radiation GO:0010212 65 32 0,000 0,07475653 0,09162721 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07475653 0,09158056 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07475653 0,09153395 ! muscle cell development GO:0055001 49 32 0,000 0,07475653 0,09148739 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07475653 0,09144088 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07475653 0,09139442 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07475653 0,091348 ! ovulation cycle GO:0042698 51 32 0,000 0,07475653 0,09130163 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07475653 0,09125531 ! hindbrain development GO:0030902 61 32 0,000 0,07475653 0,09120903 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07475653 0,0911628 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07475653 0,09111662 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,07475653 0,09107049 ! gene silencing GO:0016458 65 32 0,000 0,07475653 0,0910244 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0770016 0,09371059 ! post-embryonic development GO:0009791 69 33 0,000 0,0770016 0,09366321 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0770016 0,09361589 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0770016 0,09356861 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0770016 0,09352137 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0770016 0,09347419 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0770016 0,09342705 ! cell fate specification GO:0001708 52 33 0,000 0,0770016 0,09337996 ! sterol transport GO:0015918 57 33 0,000 0,0770016 0,09333292 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0770016 0,09328592 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0770016 0,09323897 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0770016 0,09319207 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0770016 0,09314522 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07924129 0,0958063 ! glial cell differentiation GO:0010001 63 34 0,000 0,07924129 0,09575818 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07924129 0,09571011 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07924129 0,09566209 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07924129 0,09561411 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07924129 0,09556618 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07924129 0,0955183 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07924129 0,09547047 ! mismatch repair GO:0006298 46 34 0,000 0,07924129 0,09542269 ! spermatid development GO:0007286 63 34 0,000 0,07924129 0,09537496 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07924129 0,09532727 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07924129 0,09527963 ! placenta development GO:0001890 53 34 0,000 0,07924129 0,09523204 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07924129 0,09518449 ! regulation of muscle development GO:0048634 70 35 0,000 0,08147562 0,09781953 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08147562 0,09777074 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,08147562 0,097722 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08147562 0,09767331 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08147562 0,09762467 ! odontogenesis GO:0042476 66 35 0,000 0,08147562 0,09757608 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08147562 0,09752753 ! female gonad development GO:0008585 58 35 0,000 0,08147562 0,09747903 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08147562 0,09743059 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08147562 0,09738218 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,08147562 0,09733383 ! cytokine production GO:0001816 59 35 0,000 0,08147562 0,09728553 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,08147562 0,09723727 ! neural tube formation GO:0001841 67 35 0,000 0,08147562 0,09718906 ! vesicle localization GO:0051648 64 35 0,000 0,08147562 0,0971409 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0837046 0,09974902 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0837046 0,09969964 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0837046 0,09965031 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0837046 0,09960102 ! cell junction organization GO:0034330 86 36 0,000 0,0837046 0,09955179 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0837046 0,0995026 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0837046 0,09945347 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0837046 0,09940438 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0837046 0,09935534 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0837046 0,09930635 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0837046 0,0992574 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0837046 0,09920851 ! aerobic respiration GO:0009060 55 36 0,000 0,0837046 0,09915966 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,0837046 0,09911086 ! embryonic organ development GO:0048568 57 36 0,000 0,0837046 0,09906211 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0837046 0,09901341 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08592825 0,10159379 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08592825 0,10154389 ! meiosis I GO:0007127 65 37 0,000 0,08592825 0,10149404 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,08592825 0,10144424 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08592825 0,10139449 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08592825 0,10134479 ! organic anion transport GO:0015711 68 37 0,000 0,08592825 0,10129513 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,08592825 0,10124553 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08592825 0,10119597 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08592825 0,10114646 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08592825 0,101097 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08592825 0,10104759 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,08592825 0,10099823 ! glycogen metabolic process GO:0005977 61 37 0,000 0,08592825 0,10094891 ! pigment metabolic process GO:0042440 80 37 0,000 0,08592825 0,10089964 ! spermatid differentiation GO:0048515 66 37 0,000 0,08592825 0,10085042 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,08592825 0,10080125 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,08814658 0,10335315 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,08814658 0,10330281 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08814658 0,10325251 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,08814658 0,10320227 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08814658 0,10315207 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,08814658 0,10310193 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,08814658 0,10305183 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,08814658 0,10300178 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,08814658 0,10295178 ! lipid homeostasis GO:0055088 67 38 0,000 0,08814658 0,10290182 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,08814658 0,10285192 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08814658 0,10280207 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08814658 0,10275226 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08814658 0,1027025 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,08814658 0,10265279 ! glucan metabolic process GO:0044042 62 38 0,000 0,08814658 0,10260313 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09035959 0,10512823 ! learning GO:0007612 77 39 0,000 0,09035959 0,10507742 ! ear morphogenesis GO:0042471 60 39 0,000 0,09035959 0,10502666 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09035959 0,10497594 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09035959 0,10492528 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09035959 0,10487466 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09035959 0,1048241 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09035959 0,10477358 ! RNA modification GO:0009451 57 39 0,000 0,09035959 0,10472311 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09035959 0,10467269 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09256731 0,10717851 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09256731 0,10712696 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09256731 0,10707546 ! feeding behavior GO:0007631 59 40 0,000 0,09256731 0,107024 ! negative regulation of binding GO:0051100 72 40 0,000 0,09256731 0,1069726 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09256731 0,10692124 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09256731 0,10686994 ! maintenance of protein location GO:0045185 91 40 0,000 0,09256731 0,10681868 ! cytokinesis GO:0000910 72 40 0,000 0,09256731 0,10676747 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09476974 0,10925539 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,09476974 0,10920307 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09476974 0,10915079 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09476974 0,10909857 ! gliogenesis GO:0042063 88 41 0,000 0,09476974 0,10904639 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,09476974 0,10899426 ! T cell differentiation GO:0030217 81 41 0,000 0,09476974 0,10894219 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09476974 0,10889016 ! female gamete generation GO:0007292 61 41 0,000 0,09476974 0,10883819 ! polyol metabolic process GO:0019751 66 41 0,000 0,09476974 0,10878626 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,09476974 0,10873438 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0969669 0,11120227 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,0969669 0,11114929 ! regulation of tube size GO:0035150 71 42 0,000 0,0969669 0,11109637 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0969669 0,11104349 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0969669 0,11099066 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0969669 0,11093788 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0969669 0,11088516 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0969669 0,11083248 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0969669 0,11077985 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0991588 0,11323022 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0991588 0,11317651 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0991588 0,11312285 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0991588 0,11306923 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0991588 0,11301567 ! glucose transport GO:0015758 65 43 0,000 0,0991588 0,11296216 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0991588 0,1129087 ! neural tube development GO:0021915 77 43 0,000 0,0991588 0,11285529 ! striated muscle contraction GO:0006941 77 43 0,000 0,0991588 0,11280193 ! phagocytosis GO:0006909 90 43 0,000 0,0991588 0,11274862 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0991588 0,11269536 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10134546 0,11512614 ! hexose transport GO:0008645 67 44 0,000 0,10134546 0,11507181 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10134546 0,11501753 ! male sex differentiation GO:0046661 76 44 0,000 0,10134546 0,11496331 ! double-strand break repair GO:0006302 81 44 0,000 0,10134546 0,11490913 ! biopolymer methylation GO:0043414 84 44 0,000 0,10134546 0,114855 ! B cell differentiation GO:0030183 107 44 0,000 0,10134546 0,11480093 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10134546 0,1147469 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10134546 0,11469293 ! developmental growth GO:0048589 82 44 0,000 0,10134546 0,11463901 ! maintenance of location in cell GO:0051651 97 44 0,000 0,10134546 0,11458514 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,10352688 0,11699655 ! glycolysis GO:0006096 65 45 0,000 0,10352688 0,11694163 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,10352688 0,11688675 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,10352688 0,11683192 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,10352688 0,11677715 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,10352688 0,11672243 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,10352688 0,11666776 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,10352688 0,11661314 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,10352688 0,11655857 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,10352688 0,11650405 ! cell growth GO:0016049 84 45 0,000 0,10352688 0,11644959 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10570307 0,11884186 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,10570307 0,11878636 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,10570307 0,1187309 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10570307 0,1186755 ! pigmentation GO:0043473 100 46 0,000 0,10570307 0,11862014 ! response to insulin stimulus GO:0032868 95 46 0,000 0,10570307 0,11856484 ! response to calcium ion GO:0051592 81 47 0,000 0,10787406 0,12094361 ! endosome transport GO:0016197 108 47 0,000 0,10787406 0,12088727 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,10787406 0,12083099 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,10787406 0,12077477 ! JNK cascade GO:0007254 91 47 0,000 0,10787406 0,12071859 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,10787406 0,12066247 ! methylation GO:0032259 90 47 0,000 0,10787406 0,1206064 ! mitochondrial transport GO:0006839 82 48 0,000 0,11003984 0,12297067 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11003984 0,12291358 ! cellular component disassembly GO:0022411 86 48 0,000 0,11003984 0,12285655 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11003984 0,12279956 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11003984 0,12274263 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11003984 0,12268575 ! activation of caspase activity GO:0006919 84 48 0,000 0,11003984 0,12262893 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11003984 0,12257216 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11220044 0,12492099 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,11220044 0,12486321 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,11220044 0,12480548 ! regulation of ion transport GO:0043269 77 49 0,000 0,11220044 0,12474781 ! peptide metabolic process GO:0006518 76 49 0,000 0,11220044 0,12469019 ! response to temperature stimulus GO:0009266 76 49 0,000 0,11220044 0,12463262 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11220044 0,12457511 ! endocrine system development GO:0035270 104 49 0,000 0,11220044 0,12451765 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11220044 0,12446024 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11220044 0,12440289 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11220044 0,12434558 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,11220044 0,12428833 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,11435587 0,12661768 ! neuromuscular process GO:0050905 99 50 0,000 0,11435587 0,12655944 ! regulation of ossification GO:0030278 117 50 0,000 0,11435587 0,12650125 ! inner ear development GO:0048839 79 50 0,000 0,11435587 0,12644312 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,11435587 0,12638503 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,11435587 0,12632701 ! viral infectious cycle GO:0019058 99 51 0,000 0,11650613 0,1286433 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,11650613 0,12858429 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,11650613 0,12852534 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,11650613 0,12846643 ! excretion GO:0007588 83 51 0,000 0,11650613 0,12840758 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,11650613 0,12834879 ! chromatin remodeling GO:0006338 109 51 0,000 0,11650613 0,12829005 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,11650613 0,12823136 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,11650613 0,12817273 ! vesicle organization GO:0016050 107 51 0,000 0,11650613 0,12811415 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,11650613 0,12805562 ! membrane fusion GO:0006944 110 52 0,000 0,11865125 0,13035384 ! positive regulation of growth GO:0045927 90 52 0,000 0,11865125 0,13029434 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,11865125 0,1302349 ! amino acid activation GO:0043038 92 52 0,000 0,11865125 0,13017552 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,12079123 0,13246294 ! RNA catabolic process GO:0006401 93 53 0,000 0,12079123 0,13240259 ! regulation of translational initiation GO:0006446 82 53 0,000 0,12079123 0,1323423 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,12079123 0,13228206 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,12079123 0,13222188 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,12079123 0,13216175 ! cell maturation GO:0048469 100 53 0,000 0,12079123 0,13210168 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,12079123 0,13204166 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,12079123 0,1319817 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,12292608 0,13425336 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,12292608 0,13419245 ! cell recognition GO:0008037 85 54 0,000 0,12292608 0,13413159 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,12292608 0,13407079 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,12292608 0,13401004 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,12292608 0,13394934 ! chloride transport GO:0006821 90 55 0,000 0,12505582 0,13620838 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,12505582 0,13614675 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,12505582 0,13608517 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,12505582 0,13602365 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,12505582 0,13596218 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,12505582 0,13590077 ! aging GO:0007568 103 55 0,000 0,12505582 0,13583942 ! gastrulation GO:0007369 112 55 0,000 0,12505582 0,13577812 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,12505582 0,13571687 ! RNA elongation GO:0006354 79 55 0,000 0,12505582 0,13565568 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,12505582 0,13559455 ! regulation of actin filament length GO:0030832 105 56 0,000 0,12718046 0,13783612 ! sensory perception of smell GO:0007608 80 56 0,000 0,12718046 0,13777406 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,12718046 0,13771206 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,12718046 0,13765011 ! regulation of DNA replication GO:0006275 101 56 0,000 0,12718046 0,13758822 ! proton transport GO:0015992 94 56 0,000 0,12718046 0,13752638 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,12718046 0,1374646 ! lipid modification GO:0030258 97 57 0,000 0,12930001 0,13969279 ! maintenance of location GO:0051235 118 57 0,000 0,12930001 0,13963009 ! hydrogen transport GO:0006818 97 58 0,000 0,13141449 0,14184982 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13141449 0,14178621 ! adult behavior GO:0030534 99 58 0,000 0,13141449 0,14172266 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1335239 0,14393302 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1335239 0,14386856 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1335239 0,14380416 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,1335239 0,14373982 ! DNA catabolic process GO:0006308 86 59 0,000 0,1335239 0,14367554 ! establishment of organelle localization GO:0051656 109 59 0,000 0,1335239 0,14361131 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,13562825 0,14580946 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,13562825 0,14574434 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,13562825 0,14567928 ! camera-type eye development GO:0043010 116 60 0,000 0,13562825 0,14561427 ! kidney development GO:0001822 122 60 0,000 0,13562825 0,14554932 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,13772757 0,14773631 ! mesoderm development GO:0007498 119 61 0,000 0,13772757 0,14767047 ! tRNA processing GO:0008033 89 61 0,000 0,13772757 0,14760469 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,13772757 0,14753897 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,13772757 0,14747331 ! ear development GO:0043583 103 62 0,000 0,13982186 0,14964919 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13982186 0,14958265 ! gonad development GO:0008406 98 62 0,000 0,13982186 0,14951617 ! regulation of mitosis GO:0007088 105 63 0,000 0,14191113 0,15168288 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,14191113 0,15161553 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,14191113 0,15154823 ! detection of external stimulus GO:0009581 91 63 0,000 0,14191113 0,151481 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,14191113 0,15141382 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,14191113 0,15134671 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,14399539 0,15350151 ! cell redox homeostasis GO:0045454 102 64 0,000 0,14399539 0,15343353 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,14399539 0,15336561 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,14399539 0,15329775 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,14399539 0,15322995 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,14607466 0,15537385 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,14607466 0,15530519 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,14607466 0,15523659 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,14607466 0,15516805 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,14607466 0,15509958 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,14814895 0,15723263 ! actin filament organization GO:0007015 148 66 0,000 0,14814895 0,15716331 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,14814895 0,15709404 ! extracellular matrix organization GO:0030198 133 66 0,000 0,14814895 0,15702484 ! secondary metabolic process GO:0019748 116 66 0,000 0,14814895 0,15695569 ! developmental maturation GO:0021700 116 66 0,000 0,14814895 0,15688661 ! cell projection assembly GO:0030031 120 66 0,000 0,14814895 0,15681759 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15021827 0,15893807 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15021827 0,1588682 ! activation of MAPK activity GO:0000187 115 67 0,000 0,15021827 0,1587984 ! chromosome segregation GO:0007059 113 67 0,000 0,15021827 0,15872866 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15021827 0,15865898 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15021827 0,15858936 ! hexose catabolic process GO:0019320 104 67 0,000 0,15021827 0,15851981 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15021827 0,15845031 ! activation of immune response GO:0002253 105 67 0,000 0,15021827 0,15838088 ! amino acid transport GO:0006865 125 68 0,000 0,15228263 0,16048709 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,15228263 0,16041682 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,15228263 0,16034662 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,15228263 0,16027647 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,15228263 0,16020639 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,15228263 0,16013637 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,15434205 0,16223109 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,15434205 0,16216025 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,15434205 0,16208947 ! urogenital system development GO:0001655 137 69 0,000 0,15434205 0,16201875 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,15434205 0,16194809 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,15434205 0,16187749 ! antigen processing and presentation GO:0019882 104 69 0,000 0,15434205 0,16180696 ! appendage morphogenesis GO:0035107 135 70 0,000 0,15639653 0,16388939 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,15844609 0,16596486 ! reproductive structure development GO:0048608 113 71 0,000 0,15844609 0,16589264 ! appendage development GO:0048736 136 71 0,000 0,15844609 0,16582048 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,15844609 0,16574838 ! B cell activation GO:0042113 160 71 0,000 0,15844609 0,16567635 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,15844609 0,16560438 ! regulation of immune effector process GO:0002697 137 71 0,000 0,15844609 0,16553247 ! acute inflammatory response GO:0002526 113 72 0,000 0,16049073 0,16759579 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,16049073 0,16752308 ! carbohydrate transport GO:0008643 110 72 0,000 0,16049073 0,16745043 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,16049073 0,16737785 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,16049073 0,16730533 ! learning or memory GO:0007611 147 73 0,000 0,16253048 0,16935831 ! regulation of blood pressure GO:0008217 125 73 0,000 0,16253048 0,16928499 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,16253048 0,16921174 ! fertilization GO:0009566 90 73 0,000 0,16253048 0,16913855 ! transition metal ion transport GO:0000041 126 74 0,000 0,16456534 0,1711821 ! neurotransmitter transport GO:0006836 123 74 0,000 0,16456534 0,17110812 ! meiosis GO:0007126 121 74 0,000 0,16456534 0,17103421 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,16456534 0,17096036 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,16456534 0,17088658 ! eye development GO:0001654 143 74 0,000 0,16456534 0,17081286 ! organelle localization GO:0051640 136 74 0,000 0,16456534 0,1707392 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,16659532 0,17277083 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,16659532 0,1726964 ! meiotic cell cycle GO:0051321 122 75 0,000 0,16659532 0,17262202 ! rhythmic process GO:0048511 128 75 0,000 0,16659532 0,17254771 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,16659532 0,17247347 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,16862043 0,17449495 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,16862043 0,17441993 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,16862043 0,17434498 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,16862043 0,17427009 ! regulation of catabolic process GO:0009894 161 76 0,000 0,16862043 0,17419526 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,1706407 0,17620666 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,1706407 0,17613107 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,1706407 0,17605554 ! blood coagulation GO:0007596 146 78 0,000 0,17265612 0,17805856 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,17265612 0,17798227 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,17265612 0,17790605 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,17265612 0,17782989 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,17466671 0,17982375 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,17466671 0,17974683 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,17466671 0,17966999 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,17466671 0,1795932 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,17466671 0,17951649 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,17667248 0,18150042 ! response to metal ion GO:0010038 140 80 0,000 0,17667248 0,18142295 ! muscle cell differentiation GO:0042692 159 80 0,000 0,17667248 0,18134556 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,17667248 0,18126822 ! protein import into nucleus GO:0006606 158 80 0,000 0,17667248 0,18119096 ! inorganic anion transport GO:0015698 138 80 0,000 0,17667248 0,18111375 ! T cell activation GO:0042110 168 81 0,000 0,17867344 0,18308701 ! digestion GO:0007586 112 81 0,000 0,17867344 0,18300907 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,17867344 0,18293119 ! nuclear import GO:0051170 161 81 0,000 0,17867344 0,18285338 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,18066961 0,18481763 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,18066961 0,18473909 ! response to drug GO:0042493 143 82 0,000 0,18066961 0,18466061 ! response to nutrient GO:0007584 125 82 0,000 0,18066961 0,1845822 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,18066961 0,18450385 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,18066961 0,18442557 ! regulation of lyase activity GO:0051339 160 83 0,000 0,18266099 0,18637928 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,18464759 0,18832646 ! hemostasis GO:0007599 158 84 0,000 0,18464759 0,18824666 ! regulation of ligase activity GO:0051340 142 84 0,000 0,18464759 0,18816692 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,18464759 0,18808726 ! response to unfolded protein GO:0006986 131 85 0,000 0,18662944 0,19002557 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,18662944 0,18994519 ! amine biosynthetic process GO:0009309 138 86 0,000 0,18860653 0,19187624 ! response to inorganic substance GO:0010035 153 86 0,000 0,18860653 0,19179514 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,18860653 0,19171412 ! tube morphogenesis GO:0035239 176 86 0,000 0,18860653 0,19163316 ! mitochondrion organization GO:0007005 148 86 0,000 0,18860653 0,19155226 ! alcohol catabolic process GO:0046164 130 86 0,000 0,18860653 0,19147144 ! amine transport GO:0015837 155 86 0,000 0,18860653 0,19139068 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,19057888 0,19331062 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,19057888 0,19322916 ! protein localization in nucleus GO:0034504 176 87 0,000 0,19057888 0,19314776 ! cellular respiration GO:0045333 135 88 0,000 0,19254651 0,19505975 ! regulation of neurological system process GO:0031644 148 88 0,000 0,19254651 0,19497765 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,19254651 0,19489562 ! cellular defense response GO:0006968 114 89 0,000 0,19450941 0,19679968 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,19646761 0,19869738 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,19646761 0,1986139 ! sex differentiation GO:0007548 145 90 0,000 0,19646761 0,19853048 ! sterol metabolic process GO:0016125 152 91 0,000 0,19842112 0,20042032 ! response to protein stimulus GO:0051789 149 91 0,000 0,19842112 0,20033622 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,19842112 0,20025218 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,20036994 0,2021342 ! vitamin metabolic process GO:0006766 139 92 0,000 0,20036994 0,20204948 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,20231408 0,20392446 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,20231408 0,20383906 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,20425357 0,20570702 ! female pregnancy GO:0007565 164 94 0,000 0,20425357 0,20562095 ! transcription initiation GO:0006352 153 94 0,000 0,20425357 0,20553496 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,2061884 0,20739519 ! leukocyte differentiation GO:0002521 202 96 0,000 0,20811859 0,2092492 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,20811859 0,20916179 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,20811859 0,20907446 ! positive regulation of immune response GO:0050778 156 96 0,000 0,20811859 0,2089872 ! detection of stimulus GO:0051606 151 96 0,000 0,20811859 0,20890001 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,21004416 0,21074489 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,21004416 0,21065704 ! protein ubiquitination GO:0016567 217 97 0,000 0,21004416 0,21056927 ! hormone metabolic process GO:0042445 157 97 0,000 0,21004416 0,21048157 ! response to virus GO:0009615 160 98 0,000 0,2119651 0,21231808 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,2119651 0,21222973 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,2119651 0,21214144 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,21388144 0,21397037 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,21388144 0,21388144