pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6262-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 52 24 5,000 2,434E-09 5,946E-06 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 4,127E-09 5,041E-06 GO:0045936|negative regulation of phosphate metabolic process, ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 5,000 8,404E-09 6,844E-06 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 7,126E-07 4,352E-04 ! signal complex assembly GO:0007172 47 17 3,000 1,674E-06 8,177E-04 ! regulation of intracellular protein transport GO:0033157 86 42 4,000 2,775E-06 1,13E-03 ! nuclear migration GO:0007097 13 6 2,000 2,833E-06 9,887E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,833E-06 8,651E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 3,000 3,365E-06 9,134E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 3,935E-06 9,613E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 3,935E-06 8,739E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 4,396E-06 8,949E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 4,396E-06 8,261E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 4,938E-06 8,617E-04 ! N-terminal protein amino acid acetylation GO:0006474 14 7 2,000 4,938E-06 8,043E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 4,938E-06 7,54E-04 ! cranial nerve morphogenesis GO:0021602 12 7 2,000 4,938E-06 7,097E-04 ! positive regulation of intracellular transport GO:0032388 42 22 3,000 5,039E-06 6,839E-04 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 7,26E-06 9,334E-04 ! male meiosis GO:0007140 9 8 2,000 7,871E-06 9,614E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 7,871E-06 9,156E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 7,871E-06 8,74E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 7,871E-06 8,36E-04 ! gland development GO:0048732 220 91 5,000 9E-06 9,162E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,176E-05 1,149E-03 ! macrophage differentiation GO:0030225 15 9 2,000 1,176E-05 1,105E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,184E-05 1,072E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,281E-05 1,118E-03 ! regulation of intracellular transport GO:0032386 108 57 4,000 1,281E-05 1,079E-03 ! negative regulation of protein modification process GO:0031400 66 28 3,000 1,376E-05 1,121E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 1,379E-05 1,087E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,674E-05 1,278E-03 ! induction of an organ GO:0001759 17 10 2,000 1,674E-05 1,239E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 2,000 2,292E-05 1,647E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,292E-05 1,6E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,292E-05 1,555E-03 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 22 11 2,000 2,292E-05 1,513E-03 ! cell fate specification GO:0001708 56 34 3,000 3,041E-05 1,955E-03 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 3,044E-05 1,907E-03 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 33 12 2,000 3,044E-05 1,859E-03 ! cranial nerve development GO:0021545 23 12 2,000 3,044E-05 1,814E-03 ! histone acetylation GO:0016573 27 12 2,000 3,044E-05 1,771E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 3,044E-05 1,73E-03 ! developmental induction GO:0031128 22 12 2,000 3,044E-05 1,69E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 3,268E-05 1,774E-03 ! lung development GO:0030324 165 69 4,000 3,268E-05 1,736E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 3,505E-05 1,822E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 3,754E-05 1,911E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 3,942E-05 1,966E-03 GO:0000725|recombinational repair, ! respiratory tube development GO:0030323 171 72 4,000 4,017E-05 1,963E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 4,277E-05 2,049E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 4,586E-05 2,155E-03 ! respiratory system development GO:0060541 175 74 4,000 4,586E-05 2,114E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 4,761E-05 2,154E-03 ! mammary gland development GO:0030879 93 40 3,000 5,846E-05 2,597E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 6,223E-05 2,715E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 6,223E-05 2,667E-03 ! dorsal/ventral pattern formation GO:0009953 75 42 3,000 7,102E-05 2,991E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 2,000 7,63E-05 3,159E-03 ! negative regulation of transport GO:0051051 164 85 4,000 8,912E-05 3,629E-03 ! embryonic forelimb morphogenesis GO:0035115 31 17 2,000 9,229E-05 3,696E-03 ! filopodium assembly GO:0046847 42 17 2,000 9,229E-05 3,637E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 9,229E-05 3,579E-03 ! regulation of protein transport GO:0051223 165 87 4,000 9,955E-05 3,8E-03 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein transport GO:0051222 80 46 3,000 1,019E-04 3,828E-03 ! nerve development GO:0021675 34 18 2,000 1,103E-04 4,083E-03 ! microspike assembly GO:0030035 46 18 2,000 1,103E-04 4,023E-03 ! neural tube development GO:0021915 91 47 3,000 1,109E-04 3,983E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 1,109E-04 3,926E-03 ! proximal/distal pattern formation GO:0009954 33 19 2,000 1,305E-04 4,554E-03 ! embryonic organ morphogenesis GO:0048562 34 19 2,000 1,305E-04 4,49E-03 ! regulation of cell projection organization GO:0031344 135 51 3,000 1,528E-04 5,185E-03 ! protein amino acid acetylation GO:0006473 41 20 2,000 1,529E-04 5,118E-03 ! forelimb morphogenesis GO:0035136 35 20 2,000 1,529E-04 5,049E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,529E-04 4,982E-03 GO:0010827|regulation of glucose transport, ! regulation of protein localization GO:0032880 188 97 4,000 1,664E-04 5,349E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,777E-04 5,639E-03 ! camera-type eye morphogenesis GO:0048593 47 21 2,000 1,777E-04 5,567E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,05E-04 6,339E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 2,05E-04 6,26E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to UV GO:0009411 120 55 3,000 2,052E-04 6,188E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 2,348E-04 6,996E-03 ! hypothalamus development GO:0021854 9 5 1,000 2,725E-04 8,02E-03 ! cellular sodium ion homeostasis GO:0006883 11 5 1,000 2,725E-04 7,924E-03 ! embryonic camera-type eye development GO:0031076 12 5 1,000 2,725E-04 7,831E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! microvillus organization GO:0032528 8 5 1,000 2,725E-04 7,74E-03 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,725E-04 7,651E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,725E-04 7,564E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,725E-04 7,479E-03 ! mitotic recombination GO:0006312 9 5 1,000 2,725E-04 7,396E-03 ! muscle cell proliferation GO:0033002 12 5 1,000 2,725E-04 7,315E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 2,725E-04 7,235E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,725E-04 7,157E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 2,725E-04 7,081E-03 GO:0022011|myelination in the peripheral nervous system, ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 3,026E-04 7,782E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 3,026E-04 7,701E-03 ! regulation of behavior GO:0050795 48 25 2,000 3,026E-04 7,622E-03 ! regulation of heart contraction GO:0008016 123 61 3,000 3,063E-04 7,636E-03 ! myelination GO:0042552 50 26 2,000 3,408E-04 8,409E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,684E-04 9E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 3,684E-04 8,911E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 3,819E-04 9,147E-03 ! forebrain regionalization GO:0021871 9 6 1,000 4,073E-04 9,66E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 4,073E-04 9,567E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 4,073E-04 9,476E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 4,073E-04 9,387E-03 GO:0046530|photoreceptor cell differentiation, ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 4,073E-04 9,299E-03 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 1,000 4,073E-04 9,213E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 4,073E-04 9,128E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,073E-04 9,045E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! sodium ion homeostasis GO:0055078 12 6 1,000 4,073E-04 8,964E-03 ! neural nucleus development GO:0048857 19 6 1,000 4,073E-04 8,884E-03 ! response to UV-C GO:0010225 14 6 1,000 4,073E-04 8,805E-03 ! astrocyte development GO:0014002 16 6 1,000 4,073E-04 8,728E-03 ! Schwann cell development GO:0014044 15 6 1,000 4,073E-04 8,652E-03 ! neural tube patterning GO:0021532 8 6 1,000 4,073E-04 8,577E-03 ! ectodermal gut morphogenesis GO:0048567 16 6 1,000 4,073E-04 8,504E-03 GO:0007439|ectodermal gut development, ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 4,145E-04 8,581E-03 ! protein amino acid acylation GO:0043543 59 28 2,000 4,261E-04 8,747E-03 ! embryonic limb morphogenesis GO:0030326 139 67 3,000 4,39E-04 8,937E-03 GO:0035113|embryonic appendage morphogenesis, ! cell projection assembly GO:0030031 138 68 3,000 4,645E-04 9,379E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 4,911E-04 9,834E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 5,24E-04 0,01040716 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 5,682E-04 0,01119472 ! prostate gland development GO:0030850 14 7 1,000 5,682E-04 0,01110516 ! synaptic transmission, dopaminergic GO:0001963 12 7 1,000 5,682E-04 0,01101703 ! spinal cord patterning GO:0021511 14 7 1,000 5,682E-04 0,01093028 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 5,682E-04 0,01084489 ! centrosome duplication GO:0051298 14 7 1,000 5,682E-04 0,01076082 ! dopamine biosynthetic process GO:0042416 18 7 1,000 5,682E-04 0,01067804 ! appendage morphogenesis GO:0035107 150 72 3,000 5,773E-04 0,01076598 GO:0035108|limb morphogenesis, ! ensheathment of neurons GO:0007272 64 31 2,000 5,779E-04 0,01069519 GO:0008366|axon ensheathment, ! eye morphogenesis GO:0048592 65 31 2,000 5,779E-04 0,01061477 ! appendage development GO:0048736 151 73 3,000 6,083E-04 0,01108971 GO:0060173|limb development, ! regulation of protein import into nucleus GO:0042306 69 32 2,000 6,352E-04 0,01149483 ! peripheral nervous system development GO:0007422 68 32 2,000 6,352E-04 0,0114103 ! hindbrain development GO:0030902 65 32 2,000 6,352E-04 0,01132702 ! leukocyte chemotaxis GO:0030595 55 33 2,000 6,96E-04 0,01232174 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 2,000 6,96E-04 0,01223309 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 7,55E-04 0,01317465 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,55E-04 0,01308121 ! astrocyte differentiation GO:0048708 19 8 1,000 7,55E-04 0,01298909 ! ER overload response GO:0006983 13 8 1,000 7,55E-04 0,01289826 ! embryonic eye morphogenesis GO:0048048 16 8 1,000 7,55E-04 0,01280869 ! Schwann cell differentiation GO:0014037 21 8 1,000 7,55E-04 0,01272035 ! cardiac muscle cell differentiation GO:0055007 31 8 1,000 7,55E-04 0,01263323 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,55E-04 0,01254729 ! blastocyst growth GO:0001832 19 8 1,000 7,55E-04 0,01246251 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 7,604E-04 0,01246823 ! telencephalon development GO:0021537 81 35 2,000 8,285E-04 0,013494 ! meiosis GO:0007126 143 81 3,000 8,999E-04 0,01455972 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 3,000 8,999E-04 0,01446394 ! embryonic organ development GO:0048568 67 36 2,000 9,004E-04 0,01437649 ! meiotic cell cycle GO:0051321 144 82 3,000 9,422E-04 0,01494712 ! cell proliferation in forebrain GO:0021846 18 9 1,000 9,673E-04 0,01524664 ! cerebral cortex cell migration GO:0021795 18 9 1,000 9,673E-04 0,0151489 ! microtubule bundle formation GO:0001578 22 9 1,000 9,673E-04 0,01505241 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 9,673E-04 0,01495714 ! retinoic acid receptor signaling pathway GO:0048384 16 9 1,000 9,673E-04 0,01486307 ! receptor clustering GO:0043113 20 9 1,000 9,673E-04 0,01477018 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 9,859E-04 0,01496003 GO:0045937|positive regulation of phosphate metabolic process, ! embryonic skeletal system morphogenesis GO:0048704 68 38 2,000 1,056E-03 0,015919 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,077E-03 0,01614927 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,205E-03 0,01795009 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,205E-03 0,0178413 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,205E-03 0,01773382 ! smoothened signaling pathway GO:0007224 18 10 1,000 1,205E-03 0,01762763 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,205E-03 0,01752271 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,205E-03 0,01741902 ! multicellular organism growth GO:0035264 19 10 1,000 1,205E-03 0,01731656 ! neurotransmitter biosynthetic process GO:0042136 18 10 1,000 1,205E-03 0,01721529 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,205E-03 0,0171152 ! motor axon guidance GO:0008045 22 10 1,000 1,205E-03 0,01701627 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 1,205E-03 0,01691848 ! midbrain development GO:0030901 14 10 1,000 1,205E-03 0,0168218 ! learning GO:0007612 82 40 2,000 1,227E-03 0,01702897 ! regulation of action potential in neuron GO:0019228 80 40 2,000 1,227E-03 0,01693276 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,319E-03 0,01809701 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,468E-03 0,02003102 ! neuron fate specification GO:0048665 18 11 1,000 1,468E-03 0,01991973 ! telencephalon cell migration GO:0022029 23 11 1,000 1,468E-03 0,01980968 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,468E-03 0,01970084 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,468E-03 0,01959318 ! oocyte development GO:0048599 20 11 1,000 1,468E-03 0,0194867 ! embryonic gut development GO:0048566 19 11 1,000 1,468E-03 0,01938136 ! cardiac cell differentiation GO:0035051 36 11 1,000 1,468E-03 0,01927716 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,619E-03 0,02115565 ! double-strand break repair GO:0006302 85 44 2,000 1,619E-03 0,02104312 ! developmental growth GO:0048589 88 45 2,000 1,728E-03 0,0223407 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,755E-03 0,0225673 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,755E-03 0,02244915 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,755E-03 0,02233223 ! ventral spinal cord development GO:0021517 25 12 1,000 1,755E-03 0,02221652 ! tyrosine metabolic process GO:0006570 19 12 1,000 1,755E-03 0,022102 ! forebrain cell migration GO:0021885 24 12 1,000 1,755E-03 0,02198866 ! entry into host cell GO:0030260 34 12 1,000 1,755E-03 0,02187647 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! autonomic nervous system development GO:0048483 24 12 1,000 1,755E-03 0,02176542 ! oocyte differentiation GO:0009994 21 12 1,000 1,755E-03 0,02165549 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,755E-03 0,02154667 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 15 12 1,000 1,755E-03 0,02143894 ! localization within membrane GO:0051668 26 12 1,000 1,755E-03 0,02133228 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 1,756E-03 0,02123601 ! leukocyte migration GO:0050900 75 46 2,000 1,842E-03 0,0221656 ! pigmentation GO:0043473 103 46 2,000 1,842E-03 0,02205695 ! cell growth GO:0016049 90 46 2,000 1,842E-03 0,02194935 ! response to X-ray GO:0010165 28 13 1,000 2,067E-03 0,02451395 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 2,067E-03 0,02439553 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,067E-03 0,02427824 ! digestive tract morphogenesis GO:0048546 31 13 1,000 2,067E-03 0,02416208 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,067E-03 0,02404702 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,082E-03 0,02411147 ! positive regulation of defense response GO:0031349 88 48 2,000 2,082E-03 0,02399773 ! regulation of inflammatory response GO:0050727 84 48 2,000 2,082E-03 0,02388507 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,21E-03 0,02522664 ! regulation of action potential GO:0001508 102 50 2,000 2,342E-03 0,02660947 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 2,342E-03 0,02648628 ! regulation of S phase GO:0033261 26 14 1,000 2,403E-03 0,02705608 ! cell-cell junction assembly GO:0007043 32 14 1,000 2,403E-03 0,02693197 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,403E-03 0,02680899 GO:0060675|ureteric bud morphogenesis, ! bone mineralization GO:0030282 18 14 1,000 2,403E-03 0,02668713 ! response to gamma radiation GO:0010332 30 14 1,000 2,403E-03 0,02656638 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,403E-03 0,02644671 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 2,62E-03 0,02870556 ! histone modification GO:0016570 104 52 2,000 2,62E-03 0,02857741 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,763E-03 0,03000461 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 2,763E-03 0,02987184 ! dopamine metabolic process GO:0042417 35 15 1,000 2,763E-03 0,02974025 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,767E-03 0,02964644 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 2,000 2,767E-03 0,02951698 ! embryonic skeletal system development GO:0048706 101 54 2,000 2,918E-03 0,03099804 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,918E-03 0,03086385 ! covalent chromatin modification GO:0016569 115 54 2,000 2,918E-03 0,03073081 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,918E-03 0,03059892 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 3,147E-03 0,0328583 ! pituitary gland development GO:0021983 30 16 1,000 3,147E-03 0,03271847 ! biomineral formation GO:0031214 22 16 1,000 3,147E-03 0,03257984 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,147E-03 0,03244237 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of protein catabolic process GO:0042176 126 56 2,000 3,236E-03 0,03322155 ! regulation of DNA replication GO:0006275 105 56 2,000 3,236E-03 0,03308255 ! heart morphogenesis GO:0003007 105 57 2,000 3,403E-03 0,03464169 ! glial cell development GO:0021782 28 17 1,000 3,555E-03 0,03603302 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 3,555E-03 0,03588413 GO:0031114|regulation of microtubule depolymerization, ! DNA unwinding during replication GO:0006268 26 17 1,000 3,555E-03 0,03573645 ! establishment of organelle localization GO:0051656 122 59 2,000 3,752E-03 0,03756779 ! limbic system development GO:0021761 40 18 1,000 3,985E-03 0,03973781 ! centrosome cycle GO:0007098 26 18 1,000 3,985E-03 0,03957628 ! response to retinoic acid GO:0032526 31 18 1,000 3,985E-03 0,03941605 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 3,985E-03 0,03925711 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 3,985E-03 0,03909946 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 1,000 3,985E-03 0,03894306 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,985E-03 0,03878791 ! camera-type eye development GO:0043010 126 61 2,000 4,122E-03 0,03996233 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 4,122E-03 0,03980437 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,439E-03 0,0426915 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,439E-03 0,04252409 ! memory GO:0007613 34 19 1,000 4,439E-03 0,04235798 ! cell differentiation in spinal cord GO:0021515 37 19 1,000 4,439E-03 0,04219316 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,439E-03 0,04202962 ! cerebral cortex development GO:0021987 40 19 1,000 4,439E-03 0,04186734 ! response to vitamin A GO:0033189 32 19 1,000 4,439E-03 0,04170631 ! neuromuscular junction development GO:0007528 43 19 1,000 4,439E-03 0,04154652 ! response to fungus GO:0009620 26 19 1,000 4,439E-03 0,04138795 ! regulation of protein complex assembly GO:0043254 132 63 2,000 4,514E-03 0,04192701 ! skeletal system morphogenesis GO:0048705 118 63 2,000 4,514E-03 0,04176819 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 4,915E-03 0,04530935 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,915E-03 0,04513902 ! response to vitamin GO:0033273 36 20 1,000 4,915E-03 0,04496996 ! DNA duplex unwinding GO:0032508 30 20 1,000 4,915E-03 0,04480216 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 4,915E-03 0,04463561 ! cell-cell junction organization GO:0045216 43 20 1,000 4,915E-03 0,04447029 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,915E-03 0,04430619 ! negative regulation of translation GO:0017148 32 20 1,000 4,915E-03 0,0441433 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 5,142E-03 0,04601181 ! negative regulation of cell growth GO:0030308 142 67 2,000 5,362E-03 0,04780935 ! myeloid cell differentiation GO:0030099 126 67 2,000 5,362E-03 0,04763549 ! lipid phosphorylation GO:0046834 43 21 1,000 5,413E-03 0,04791727 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 5,413E-03 0,04774428 ! neurotransmitter metabolic process GO:0042133 39 21 1,000 5,413E-03 0,04757254 ! diencephalon development GO:0021536 36 21 1,000 5,413E-03 0,04740203 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 5,413E-03 0,04723273 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 5,413E-03 0,04706465 ! negative regulation of cell size GO:0045792 144 69 2,000 5,82E-03 0,05041844 ! urogenital system development GO:0001655 149 69 2,000 5,82E-03 0,05024029 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 5,934E-03 0,05104789 ! reciprocal meiotic recombination GO:0007131 44 22 1,000 5,934E-03 0,05086877 ! hindlimb morphogenesis GO:0035137 47 22 1,000 5,934E-03 0,05069091 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 5,934E-03 0,05051429 ! ureteric bud development GO:0001657 50 22 1,000 5,934E-03 0,05033889 ! cell aging GO:0007569 48 22 1,000 5,934E-03 0,05016471 ! G1 phase GO:0051318 44 22 1,000 5,934E-03 0,04999173 ! peptidyl-serine modification GO:0018209 50 22 1,000 5,934E-03 0,04981993 ! positive regulation of B cell activation GO:0050871 42 22 1,000 5,934E-03 0,04964932 ! gut development GO:0048565 44 22 1,000 5,934E-03 0,04947987 ! protein stabilization GO:0050821 41 22 1,000 5,934E-03 0,04931157 ! response to ethanol GO:0045471 47 23 1,000 6,477E-03 0,05363961 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 6,477E-03 0,0534584 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 6,477E-03 0,0532784 GO:0060415|muscle tissue morphogenesis, ! nerve-nerve synaptic transmission GO:0007270 59 23 1,000 6,477E-03 0,05309962 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,042E-03 0,05753454 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 7,042E-03 0,05734276 ! pallium development GO:0021543 56 24 1,000 7,042E-03 0,05715225 ! oogenesis GO:0048477 44 24 1,000 7,042E-03 0,056963 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 7,042E-03 0,05677501 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 7,042E-03 0,05658825 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,042E-03 0,05640271 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 7,042E-03 0,05621839 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 7,064E-03 0,05621446 ! organelle localization GO:0051640 155 74 2,000 7,064E-03 0,05603195 ! regulation of transcription factor activity GO:0051090 137 75 2,000 7,33E-03 0,05795578 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 2,000 7,33E-03 0,05776882 ! eye development GO:0001654 155 75 2,000 7,33E-03 0,05758307 ! learning or memory GO:0007611 161 76 2,000 7,603E-03 0,05952944 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 7,628E-03 0,05953494 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 7,628E-03 0,05934534 ! phototransduction GO:0007602 37 25 1,000 7,628E-03 0,05915694 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 7,628E-03 0,05896973 ! negative regulation of DNA replication GO:0008156 45 25 1,000 7,628E-03 0,05878371 ! receptor metabolic process GO:0043112 53 25 1,000 7,628E-03 0,05859885 ! interaction with host GO:0051701 66 25 1,000 7,628E-03 0,05841516 ! regulation of catabolic process GO:0009894 173 77 2,000 7,881E-03 0,06016395 ! initiation of viral infection GO:0019059 60 26 1,000 8,235E-03 0,06267267 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,235E-03 0,06247803 ! microtubule organizing center organization GO:0031023 42 26 1,000 8,235E-03 0,0622846 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 1,000 8,235E-03 0,06209237 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 8,235E-03 0,06190131 ! blastocyst development GO:0001824 50 26 1,000 8,235E-03 0,06171143 ! neural tube closure GO:0001843 58 26 1,000 8,235E-03 0,06152271 GO:0060606|tube closure, ! response to steroid hormone stimulus GO:0048545 147 79 2,000 8,455E-03 0,06297126 ! tube lumen formation GO:0035148 59 27 1,000 8,863E-03 0,06581374 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 8,863E-03 0,06561431 ! cellular response to oxidative stress GO:0034599 43 27 1,000 8,863E-03 0,06541608 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 8,863E-03 0,06521904 ! response to hypoxia GO:0001666 178 81 2,000 9,052E-03 0,06641199 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 9,512E-03 0,06957559 ! neuron fate commitment GO:0048663 52 28 1,000 9,512E-03 0,0693679 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 9,512E-03 0,06916145 ! dendrite development GO:0016358 67 28 1,000 9,512E-03 0,06895622 ! response to oxygen levels GO:0070482 183 83 2,000 9,675E-03 0,06992547 ! response to nutrient GO:0007584 135 84 2,000 9,995E-03 0,07202622 ! catechol metabolic process GO:0009712 55 29 1,000 0,01018171 0,07315861 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01018171 0,07294407 ! primary neural tube formation GO:0014020 61 29 1,000 0,01018171 0,07273078 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01018171 0,07251874 ! somitogenesis GO:0001756 52 29 1,000 0,01018171 0,07230793 ! negative regulation of growth GO:0045926 168 85 2,000 0,01032087 0,07308372 ! phenol metabolic process GO:0018958 56 30 1,000 0,01087155 0,0767607 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 1,000 0,01087155 0,07653949 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01087155 0,07631955 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01087155 0,07610087 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 0,01087155 0,07588344 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01087155 0,07566725 ! cell junction assembly GO:0034329 85 31 1,000 0,01158146 0,08037929 ! detection of light stimulus GO:0009583 44 31 1,000 0,01158146 0,08015158 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01158146 0,07992517 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01158146 0,07970003 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01158146 0,07947615 ! response to heat GO:0009408 54 31 1,000 0,01158146 0,07925353 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01168729 0,07975432 ! tube morphogenesis GO:0035239 194 89 2,000 0,01168729 0,07953216 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01204436 0,08173433 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01204436 0,08150792 ! metanephros development GO:0001656 81 32 1,000 0,01231121 0,08308367 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01231121 0,08285479 ! ossification GO:0001503 205 91 2,000 0,01240764 0,08327437 ! bone development GO:0060348 206 92 2,000 0,01277717 0,0855195 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,01306058 0,08717757 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01306058 0,08694003 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01315294 0,08731694 ! regulation of membrane potential GO:0042391 179 94 2,000 0,01353498 0,08960964 ! glial cell differentiation GO:0010001 67 34 1,000 0,01382934 0,091311 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01382934 0,09106488 ! regulation of defense response GO:0031347 171 95 2,000 0,0139233 0,09143715 ! sex differentiation GO:0007548 171 96 2,000 0,01431791 0,09377655 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01461726 0,09548122 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01461726 0,0952266 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01461726 0,09497334 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,01461726 0,09472142 ! leukocyte differentiation GO:0002521 232 98 2,000 0,01512606 0,09775914 ! forebrain development GO:0030900 210 98 2,000 0,01512606 0,0975012 ! regulation of muscle development GO:0048634 82 36 1,000 0,01542414 0,09916099 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01542414 0,09890072 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,0159595 0,10206562 GO:0060538|skeletal muscle organ development, ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01624975 0,10365047 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01624975 0,10338055 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01624975 0,10311202 ! odontogenesis GO:0042476 74 37 1,000 0,01624975 0,1028449 ! cell junction organization GO:0034330 96 37 1,000 0,01624975 0,10257915 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01624975 0,10231477 ! female gonad development GO:0008585 71 37 1,000 0,01624975 0,10205175 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01624975 0,10179008 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01624975 0,10152974 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01709386 0,1065314 ! meiosis I GO:0007127 74 38 1,000 0,01709386 0,10626033 ! regulation of protein stability GO:0031647 77 38 1,000 0,01709386 0,10599064 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01709386 0,1057223 ! neural tube formation GO:0001841 79 38 1,000 0,01709386 0,10545533 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,01795628 0,1104967 ! negative regulation of binding GO:0051100 71 39 1,000 0,01795628 0,11021907 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01795628 0,10994283 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,01795628 0,10966798 ! glucan metabolic process GO:0044042 64 39 1,000 0,01795628 0,10939449 GO:0006073|cellular glucan metabolic process, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01883678 0,11447325 GO:0046660|female sex differentiation, ! gliogenesis GO:0042063 91 41 1,000 0,01973515 0,11963515 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01973515 0,11933902 ! maintenance of protein location GO:0045185 95 41 1,000 0,01973515 0,11904436 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01973515 0,11875114 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,02065118 0,12395781 ! cytokinesis GO:0000910 84 42 1,000 0,02065118 0,12365399 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,02065118 0,12335166 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02158466 0,12861299 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02158466 0,12830006 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,02158466 0,12798866 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02158466 0,12767876 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02158466 0,12737035 ! segmentation GO:0035282 78 43 1,000 0,02158466 0,12706344 ! neuron migration GO:0001764 85 43 1,000 0,02158466 0,126758 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,02253539 0,13202387 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02253539 0,13170803 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,02253539 0,13139369 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02350316 0,13671003 ! female gamete generation GO:0007292 71 45 1,000 0,02350316 0,13638531 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02350316 0,13606212 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02448776 0,14142696 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02603154 0,14998831 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02603154 0,14963539 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02603154 0,14928414 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02603154 0,14893453 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02603154 0,14858655 ! neuron fate determination GO:0048664 7 5 0,000 0,02603154 0,14824019 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02603154 0,14789545 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02603154 0,1475523 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02603154 0,14721075 ! polyol transport GO:0015791 12 5 0,000 0,02603154 0,14687077 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02603154 0,14653236 ! response to superoxide GO:0000303 10 5 0,000 0,02603154 0,1461955 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02603154 0,14586019 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02603154 0,14552641 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02603154 0,14519416 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02603154 0,14486342 ! female meiosis GO:0007143 10 5 0,000 0,02603154 0,14453419 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02603154 0,14420644 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02603154 0,14388019 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02603154 0,1435554 ! cobalt ion transport GO:0006824 11 5 0,000 0,02603154 0,14323208 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02603154 0,14291021 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02603154 0,14258978 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02603154 0,14227079 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02603154 0,14195322 ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02603154 0,14163707 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02603154 0,14132232 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02603154 0,14100896 ! transposition GO:0032196 9 5 0,000 0,02603154 0,140697 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02603154 0,14038641 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02603154 0,14007719 ! negative chemotaxis GO:0050919 16 5 0,000 0,02603154 0,13976932 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02603154 0,13946281 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02603154 0,13915764 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02603154 0,1388538 ! behavioral response to pain GO:0048266 10 5 0,000 0,02603154 0,13855129 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02603154 0,13825009 ! Notch receptor processing GO:0007220 11 5 0,000 0,02603154 0,1379502 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02603154 0,13765161 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02603154 0,1373543 ! micturition GO:0060073 9 5 0,000 0,02603154 0,13705828 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02603154 0,13676353 ! copulation GO:0007620 9 5 0,000 0,02603154 0,13647005 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02603154 0,13617782 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02603154 0,13588684 ! bioluminescence GO:0008218 9 5 0,000 0,02603154 0,1355971 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02603154 0,1353086 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02603154 0,13502132 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02603154 0,13473526 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02603154 0,13445041 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02603154 0,13416676 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02603154 0,1338843 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02603154 0,13360303 ! grooming behavior GO:0007625 6 5 0,000 0,02603154 0,13332294 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02603154 0,13304402 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02603154 0,13276627 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02603154 0,13248967 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02603154 0,13221422 ! response to protozoan GO:0001562 13 5 0,000 0,02603154 0,13193992 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02603154 0,13166675 ! lymph vessel development GO:0001945 10 5 0,000 0,02603154 0,13139472 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02603154 0,1311238 ! endochondral ossification GO:0001958 17 5 0,000 0,02603154 0,130854 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02603154 0,1305853 ! single strand break repair GO:0000012 8 5 0,000 0,02603154 0,13031771 ! parathyroid gland development GO:0060017 14 5 0,000 0,02603154 0,13005121 ! anagen GO:0042640 7 5 0,000 0,02603154 0,1297858 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02603154 0,12952147 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02603154 0,12925822 ! cytokine secretion GO:0050663 15 5 0,000 0,02603154 0,12899603 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02603154 0,1287349 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02603154 0,12847483 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02603154 0,12821581 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02603154 0,12795783 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02603154 0,12770089 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02603154 0,12744497 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02603154 0,12719008 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02603154 0,12693621 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02603154 0,12668335 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02603154 0,1264315 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02603154 0,12618064 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02603154 0,12593078 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02603154 0,1256819 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02603154 0,12543401 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02603154 0,12518709 ! valine metabolic process GO:0006573 12 5 0,000 0,02603154 0,12494114 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02603154 0,12469616 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02603154 0,12445214 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02603154 0,12420907 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02603154 0,12396694 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02603154 0,12372576 ! polyol catabolic process GO:0046174 9 5 0,000 0,02603154 0,12348552 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02603154 0,12324621 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02603154 0,12300782 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02603154 0,12277035 ! muscle cell migration GO:0014812 8 5 0,000 0,02603154 0,1225338 ! mitochondrial fission GO:0000266 8 5 0,000 0,02603154 0,12229816 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02603154 0,12206342 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02603154 0,12182958 ! mRNA transcription GO:0009299 10 5 0,000 0,02603154 0,12159664 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02603154 0,12136458 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02603154 0,12113341 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02603154 0,12090312 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02603154 0,1206737 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02603154 0,12044516 ! monocyte activation GO:0042117 10 5 0,000 0,02603154 0,12021747 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02603154 0,11999065 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02603154 0,11976467 ! response to food GO:0032094 6 5 0,000 0,02603154 0,11953955 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02603154 0,11931528 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02603154 0,11909184 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02603154 0,11886924 ! forebrain neuron development GO:0021884 13 5 0,000 0,02603154 0,11864747 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02603154 0,11842652 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02603154 0,1182064 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02603154 0,11798709 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02603154 0,1177686 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02603154 0,11755091 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02603154 0,11733403 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02603154 0,11711794 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02603154 0,11690265 ! lipid glycosylation GO:0030259 7 5 0,000 0,02603154 0,11668815 ! nucleobase transport GO:0015851 6 5 0,000 0,02603154 0,11647444 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02603154 0,1162615 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02603154 0,11604935 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02603154 0,11583796 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02603154 0,11562735 ! basic amino acid transport GO:0015802 12 5 0,000 0,02603154 0,1154175 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02603154 0,11520841 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02603154 0,11500008 ! actin nucleation GO:0045010 11 5 0,000 0,02603154 0,11479249 ! depurination GO:0045007 5 5 0,000 0,02603154 0,11458566 ! depyrimidination GO:0045008 10 5 0,000 0,02603154 0,11437957 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02603154 0,11417422 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02603154 0,11396961 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02603154 0,11376573 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02603154 0,11356258 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02603154 0,11336015 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02603154 0,11315844 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02603154 0,11295745 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02603154 0,11275717 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02603154 0,1125576 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02603154 0,11235873 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02603154 0,11216057 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02603154 0,1119631 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02603154 0,11176633 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02603154 0,11157025 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02603154 0,11137485 ! response to arsenic GO:0046685 11 5 0,000 0,02603154 0,11118014 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02603154 0,11098611 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02603154 0,11079276 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02603154 0,11060007 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02603154 0,11040806 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02603154 0,11021671 ! response to mercury ion GO:0046689 8 5 0,000 0,02603154 0,11002602 ! response to cadmium ion GO:0046686 7 5 0,000 0,02603154 0,109836 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02603154 0,10964662 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02603154 0,1094579 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02603154 0,10926983 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02603154 0,10908241 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02603154 0,10889562 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02603154 0,10870947 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02603154 0,10852396 ! decidualization GO:0046697 11 5 0,000 0,02603154 0,10833908 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02603154 0,10815483 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02603154 0,10797121 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02603154 0,10778821 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02603154 0,10760582 ! embryonic cleavage GO:0040016 6 5 0,000 0,02603154 0,10742406 ! peroxisome fission GO:0016559 5 5 0,000 0,02603154 0,1072429 ! histone demethylation GO:0016577 13 5 0,000 0,02603154 0,10706236 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02603154 0,10688242 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02603154 0,10670309 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02603154 0,10652436 ! metaphase plate congression GO:0051310 7 5 0,000 0,02603154 0,10634622 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02603154 0,10616868 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02603154 0,10599174 ! enteric nervous system development GO:0048484 8 5 0,000 0,02603154 0,10581538 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02603154 0,1056396 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02603154 0,10546441 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02603154 0,1052898 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02603154 0,10511577 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02603154 0,10494231 ! B cell homeostasis GO:0001782 13 5 0,000 0,02603154 0,10476943 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02603154 0,10459711 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02603154 0,10442536 ! metaphase GO:0051323 11 5 0,000 0,02603154 0,10425417 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02603154 0,10408354 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02603154 0,10391347 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02603154 0,10374395 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02603154 0,10357499 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02603154 0,10340657 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02603154 0,1032387 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02603154 0,10307138 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02603154 0,1029046 ! response to redox state GO:0051775 6 5 0,000 0,02603154 0,10273836 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02603154 0,10257265 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02603154 0,10240748 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02603154 0,10224283 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02603154 0,10207872 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02603154 0,10191513 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02603154 0,10175207 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02603154 0,10158952 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02603154 0,1014275 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02603154 0,10126599 ! striatum development GO:0021756 14 5 0,000 0,02603154 0,101105 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02603154 0,10094451 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02603154 0,10078454 ! glial cell migration GO:0008347 10 5 0,000 0,02603154 0,10062507 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02603154 0,1004661 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02603154 0,10030764 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02603154 0,10014967 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02603154 0,0999922 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02603154 0,09983523 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02603154 0,09967875 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02603154 0,09952276 ! neuroprotection GO:0043526 8 5 0,000 0,02603154 0,09936725 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02603154 0,09921223 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02603154 0,0990577 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02603154 0,09890364 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02603154 0,09875007 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02603154 0,09859696 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02603154 0,09844434 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02603154 0,09829218 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02603154 0,0981405 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02603154 0,09798928 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02603154 0,09783853 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02603154 0,09768824 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02603154 0,09753841 ! spindle assembly GO:0051225 6 5 0,000 0,02603154 0,09738904 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02603154 0,09724013 ! protein palmitoylation GO:0018345 12 5 0,000 0,02603154 0,09709167 ! drug metabolic process GO:0017144 7 5 0,000 0,02603154 0,09694366 ! stem cell division GO:0017145 11 5 0,000 0,02603154 0,09679611 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02603154 0,096649 ! organ regeneration GO:0031100 7 5 0,000 0,02603154 0,09650234 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02603154 0,09635612 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02603154 0,09621035 ! endosome transport GO:0016197 127 48 1,000 0,02650668 0,09781845 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02650668 0,09767091 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02754059 0,1013278 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02754059 0,10117542 ! protein homooligomerization GO:0051260 84 49 1,000 0,02754059 0,10102351 ! endocrine system development GO:0035270 109 50 1,000 0,02859054 0,10471766 ! viral infectious cycle GO:0019058 104 51 1,000 0,02965633 0,1084587 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02965633 0,10829658 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02965633 0,10813495 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02965633 0,10797379 ! positive regulation of binding GO:0051099 88 52 1,000 0,03073777 0,11174461 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03073777 0,11157857 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,03073777 0,11141302 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03073777 0,11124797 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,03073777 0,1110834 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03073777 0,11091932 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03115639 0,11226409 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03115639 0,11209876 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03115639 0,1119339 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03115639 0,11176954 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03115639 0,11160565 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03115639 0,11144225 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03115639 0,11127932 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03115639 0,11111687 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03115639 0,11095489 ! response to oxygen radical GO:0000305 11 6 0,000 0,03115639 0,11079338 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03115639 0,11063235 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03115639 0,11047178 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03115639 0,11031167 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03115639 0,11015203 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03115639 0,10999285 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03115639 0,10983413 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03115639 0,10967587 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03115639 0,10951806 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03115639 0,10936071 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03115639 0,10920381 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03115639 0,10904736 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03115639 0,10889135 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03115639 0,10873579 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03115639 0,10858068 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03115639 0,108426 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03115639 0,10827177 ! malate metabolic process GO:0006108 13 6 0,000 0,03115639 0,10811798 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03115639 0,10796462 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03115639 0,10781169 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03115639 0,1076592 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03115639 0,10750714 ! protein refolding GO:0042026 15 6 0,000 0,03115639 0,10735551 ! opsonization GO:0008228 8 6 0,000 0,03115639 0,1072043 ! mating behavior GO:0007617 7 6 0,000 0,03115639 0,10705352 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03115639 0,10690317 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03115639 0,10675323 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03115639 0,10660372 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03115639 0,10645462 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03115639 0,10630594 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03115639 0,10615768 ! toxin metabolic process GO:0009404 11 6 0,000 0,03115639 0,10600983 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03115639 0,10586238 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03115639 0,10571535 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03115639 0,10556873 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03115639 0,10542251 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03115639 0,1052767 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03115639 0,10513129 ! thymic T cell selection GO:0045061 16 6 0,000 0,03115639 0,10498628 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03115639 0,10484167 ! protein lipoylation GO:0009249 10 6 0,000 0,03115639 0,10469746 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03115639 0,10455365 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03115639 0,10441023 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03115639 0,1042672 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03115639 0,10412456 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03115639 0,10398232 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03115639 0,10384046 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03115639 0,10369898 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03115639 0,1035579 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03115639 0,10341719 ! hyperosmotic response GO:0006972 10 6 0,000 0,03115639 0,10327687 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03115639 0,10313693 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03115639 0,10299737 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03115639 0,10285818 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03115639 0,10271937 ! urea metabolic process GO:0019627 7 6 0,000 0,03115639 0,10258094 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03115639 0,10244287 ! neutrophil activation GO:0042119 7 6 0,000 0,03115639 0,10230518 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03115639 0,10216786 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03115639 0,1020309 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03115639 0,10189432 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03115639 0,10175809 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03115639 0,10162224 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03115639 0,10148674 ! neuron apoptosis GO:0051402 15 6 0,000 0,03115639 0,1013516 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03115639 0,10121683 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03115639 0,10108241 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03115639 0,10094835 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03115639 0,10081464 ! carnitine transport GO:0015879 10 6 0,000 0,03115639 0,10068129 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03115639 0,10054829 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03115639 0,10041564 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03115639 0,10028334 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03115639 0,10015139 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03115639 0,10001978 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03115639 0,09988852 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03115639 0,09975761 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03115639 0,09962704 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03115639 0,0994968 GO:0045686|negative regulation of glial cell differentiation, ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03115639 0,09936691 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03115639 0,09923736 ! interaction with symbiont GO:0051702 14 6 0,000 0,03115639 0,09910814 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03115639 0,09897926 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03115639 0,09885072 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03115639 0,09872251 ! response to copper ion GO:0046688 10 6 0,000 0,03115639 0,09859463 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03115639 0,09846708 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03115639 0,09833986 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03115639 0,09821297 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03115639 0,09808641 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03115639 0,09796017 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03115639 0,09783426 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03115639 0,09770867 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03115639 0,0975834 ! hair follicle maturation GO:0048820 8 6 0,000 0,03115639 0,09745846 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03115639 0,09733383 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03115639 0,09720952 ! response to pheromone GO:0019236 6 6 0,000 0,03115639 0,09708553 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03115639 0,09696185 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03115639 0,09683849 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03115639 0,09671544 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03115639 0,09659271 ! subpallium development GO:0021544 15 6 0,000 0,03115639 0,09647028 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03115639 0,09634817 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03115639 0,09622637 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03115639 0,09610487 ! G2 phase GO:0051319 16 6 0,000 0,03115639 0,09598368 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03115639 0,09586279 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03115639 0,09574221 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03115639 0,09562193 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03115639 0,09550195 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03115639 0,09538227 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03115639 0,0952629 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03115639 0,09514382 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03115639 0,09502504 ! receptor internalization GO:0031623 11 6 0,000 0,03115639 0,09490655 ! plasminogen activation GO:0031639 9 6 0,000 0,03115639 0,09478836 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03115639 0,09467047 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03115639 0,09455286 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03115639 0,09443555 ! protein deubiquitination GO:0016579 16 6 0,000 0,03115639 0,09431853 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03115639 0,0942018 ! protein destabilization GO:0031648 9 6 0,000 0,03115639 0,09408536 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03115639 0,0939692 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03115639 0,09385334 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03115639 0,09373775 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03115639 0,09362245 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03115639 0,09350744 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03115639 0,09339271 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03115639 0,09327825 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03115639 0,09316408 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03115639 0,09305019 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03115639 0,09293657 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03115639 0,09282324 ! neural plate development GO:0001840 9 6 0,000 0,03115639 0,09271018 ! catecholamine transport GO:0051937 9 6 0,000 0,03115639 0,09259739 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03115639 0,09248488 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03115639 0,09237264 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03115639 0,09226067 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03115639 0,09214898 ! maternal placenta development GO:0001893 12 6 0,000 0,03115639 0,09203755 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03115639 0,09192639 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03115639 0,09181551 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03115639 0,09170489 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03115639 0,09159453 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03115639 0,09148444 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03115639 0,09137462 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03115639 0,09126505 GO:0055081|anion homeostasis, ! positive regulation of growth GO:0045927 96 53 1,000 0,03183467 0,09314024 ! chromatin remodeling GO:0006338 122 53 1,000 0,03183467 0,09302883 ! synapse organization GO:0050808 102 53 1,000 0,03183467 0,09291768 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03294684 0,09604907 ! regulation of translational initiation GO:0006446 87 54 1,000 0,03294684 0,09593459 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03294684 0,09582038 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03407408 0,09898095 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03407408 0,09886339 ! cell maturation GO:0048469 107 55 1,000 0,03407408 0,09874612 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03407408 0,09862912 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03521621 0,10181445 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,03521621 0,1016941 ! RNA elongation GO:0006354 90 56 1,000 0,03521621 0,10157404 ! tRNA transcription GO:0009304 17 7 0,000 0,03625442 0,10444521 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03625442 0,10432219 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03625442 0,10419946 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03625442 0,10407701 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03625442 0,10395486 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03625442 0,10383299 ! sleep GO:0030431 16 7 0,000 0,03625442 0,1037114 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03625442 0,1035901 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03625442 0,10346909 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03625442 0,10334835 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03625442 0,1032279 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03625442 0,10310773 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03625442 0,10298784 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03625442 0,10286822 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03625442 0,10274889 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03625442 0,10262983 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03625442 0,10251104 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03625442 0,10239253 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03625442 0,1022743 ! glycolipid transport GO:0046836 11 7 0,000 0,03625442 0,10215633 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03625442 0,10203864 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03625442 0,10192122 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03625442 0,10180407 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03625442 0,10168719 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03625442 0,10157057 ! mRNA stabilization GO:0048255 18 7 0,000 0,03625442 0,10145423 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03625442 0,10133815 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03625442 0,10122233 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03625442 0,10110678 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03625442 0,10099149 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03625442 0,10087647 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03625442 0,10076171 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03625442 0,1006472 ! lipoprotein transport GO:0042953 14 7 0,000 0,03625442 0,10053296 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03625442 0,10041898 ! rhythmic behavior GO:0007622 17 7 0,000 0,03625442 0,10030525 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03625442 0,10019179 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03625442 0,10007858 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03625442 0,09996562 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03625442 0,09985292 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03625442 0,09974047 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03625442 0,09962828 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03625442 0,09951634 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03625442 0,09940465 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03625442 0,09929321 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03625442 0,09918202 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03625442 0,09907107 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03625442 0,09896038 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03625442 0,09884993 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03625442 0,09873973 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03625442 0,09862978 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03625442 0,09852007 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03625442 0,0984106 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03625442 0,09830138 ! adrenal gland development GO:0030325 17 7 0,000 0,03625442 0,09819239 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03625442 0,09808365 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03625442 0,09797515 ! ovulation GO:0030728 10 7 0,000 0,03625442 0,09786689 ! adenohypophysis development GO:0021984 11 7 0,000 0,03625442 0,09775887 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03625442 0,09765109 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03625442 0,09754355 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03625442 0,09743624 ! microtubule nucleation GO:0007020 21 7 0,000 0,03625442 0,09732916 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03625442 0,09722233 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03625442 0,09711572 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03625442 0,09700935 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03625442 0,09690322 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03625442 0,09679731 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03625442 0,09669164 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03625442 0,09658619 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03625442 0,09648098 ! galactose metabolic process GO:0006012 13 7 0,000 0,03625442 0,096376 ! vesicle fusion GO:0006906 20 7 0,000 0,03625442 0,09627124 ! response to dietary excess GO:0002021 8 7 0,000 0,03625442 0,09616671 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03625442 0,09606241 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03625442 0,09595833 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03625442 0,09585448 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03625442 0,09575085 ! organ growth GO:0035265 15 7 0,000 0,03625442 0,09564745 ! nucleoside transport GO:0015858 11 7 0,000 0,03625442 0,09554427 ! nucleoside salvage GO:0043174 11 7 0,000 0,03625442 0,09544131 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03625442 0,09533858 ! male sex determination GO:0030238 15 7 0,000 0,03625442 0,09523606 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03625442 0,09513377 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03625442 0,09503169 ! parturition GO:0007567 16 7 0,000 0,03625442 0,09492984 ! rRNA modification GO:0000154 14 7 0,000 0,03625442 0,0948282 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03625442 0,09472678 ! spindle checkpoint GO:0031577 16 7 0,000 0,03625442 0,09462558 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03625442 0,09452459 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03625442 0,09442382 ! monocyte differentiation GO:0030224 16 7 0,000 0,03625442 0,09432326 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03625442 0,09422291 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03625442 0,09412278 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03625442 0,09402287 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03625442 0,09392316 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03625442 0,09382366 ! fibrinolysis GO:0042730 11 7 0,000 0,03625442 0,09372438 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03625442 0,09362531 ! eating behavior GO:0042755 8 7 0,000 0,03625442 0,09352644 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03625442 0,09342778 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03625442 0,09332934 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03625442 0,09323109 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03625442 0,09313306 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03625442 0,09303523 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03625442 0,09293761 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03625442 0,09284019 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03625442 0,09274297 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03625442 0,09264596 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03625442 0,09254915 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03625442 0,09245255 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03625442 0,09235614 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03625442 0,09225994 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03625442 0,09216393 ! histone ubiquitination GO:0016574 9 7 0,000 0,03625442 0,09206813 ! regulation of meiosis GO:0040020 12 7 0,000 0,03625442 0,09197252 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03625442 0,09187712 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03625442 0,09178191 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03625442 0,09168689 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03625442 0,09159208 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03625442 0,09149746 ! transcription termination GO:0006353 14 7 0,000 0,03625442 0,09140303 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03625442 0,0913088 ! anaphase GO:0051322 18 7 0,000 0,03625442 0,09121477 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03625442 0,09112093 ! axonal fasciculation GO:0007413 19 7 0,000 0,03625442 0,09102728 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03625442 0,09093382 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03625442 0,09084055 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03625442 0,09074748 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03625442 0,0906546 ! diuresis GO:0030146 12 7 0,000 0,03625442 0,0905619 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03625442 0,0904694 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03625442 0,09037708 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03625442 0,09028495 ! antibiotic transport GO:0042891 9 7 0,000 0,03625442 0,09019301 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03625442 0,09010126 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03625442 0,09000969 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03625442 0,08991831 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03625442 0,08982712 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03625442 0,08973611 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03625442 0,08964528 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03625442 0,08955464 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03625442 0,08946418 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03625442 0,0893739 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03625442 0,08928381 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03625442 0,0891939 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03625442 0,08910416 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03625442 0,08901461 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03625442 0,08892524 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03625442 0,08883605 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03625442 0,08874703 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03625442 0,0886582 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03625442 0,08856954 ! muscle adaptation GO:0043500 13 7 0,000 0,03625442 0,08848106 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03625442 0,08839275 ! retina homeostasis GO:0001895 12 7 0,000 0,03625442 0,08830463 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03625442 0,08821667 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03625442 0,0881289 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03625442 0,08804129 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03625442 0,08795386 ! muscle fiber development GO:0048747 131 57 1,000 0,03637305 0,08815413 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03637305 0,08806676 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03637305 0,08797957 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,03754441 0,09072303 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,03754441 0,09063339 ! aging GO:0007568 112 58 1,000 0,03754441 0,09054392 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,03754441 0,09045462 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03754441 0,0903655 ! maintenance of location GO:0051235 124 58 1,000 0,03754441 0,09027656 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,03992995 0,09591825 ! lipid modification GO:0030258 112 60 1,000 0,03992995 0,09582403 ! kidney development GO:0001822 133 60 1,000 0,03992995 0,09572999 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04132576 0,09897925 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04132576 0,09888231 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04132576 0,09878556 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04132576 0,09868899 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04132576 0,09859262 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04132576 0,09849643 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04132576 0,09840043 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04132576 0,09830461 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04132576 0,09820899 ! meiotic prophase I GO:0007128 14 8 0,000 0,04132576 0,09811355 ! response to zinc ion GO:0010043 12 8 0,000 0,04132576 0,09801829 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04132576 0,09792322 ! oligopeptide transport GO:0006857 16 8 0,000 0,04132576 0,09782833 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04132576 0,09773363 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04132576 0,09763911 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04132576 0,09754477 ! signal peptide processing GO:0006465 12 8 0,000 0,04132576 0,09745062 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04132576 0,09735664 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04132576 0,09726285 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04132576 0,09716924 ! succinate metabolic process GO:0006105 17 8 0,000 0,04132576 0,09707581 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04132576 0,09698255 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04132576 0,09688948 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04132576 0,09679658 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04132576 0,09670387 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04132576 0,09661133 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04132576 0,09651897 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04132576 0,09642678 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04132576 0,09633477 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04132576 0,09624293 ! reflex GO:0060004 17 8 0,000 0,04132576 0,09615127 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04132576 0,09605979 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04132576 0,09596848 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04132576 0,09587734 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04132576 0,09578637 ! pigment granule organization GO:0048753 17 8 0,000 0,04132576 0,09569558 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04132576 0,09560496 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04132576 0,09551451 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04132576 0,09542423 ! histidine catabolic process GO:0006548 10 8 0,000 0,04132576 0,09533412 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04132576 0,09524419 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04132576 0,09515442 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04132576 0,09506482 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04132576 0,09497539 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04132576 0,09488613 ! melanin metabolic process GO:0006582 17 8 0,000 0,04132576 0,09479703 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04132576 0,0947081 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04132576 0,09461934 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04132576 0,09453075 ! macrophage activation GO:0042116 13 8 0,000 0,04132576 0,09444232 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04132576 0,09435405 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04132576 0,09426596 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04132576 0,09417802 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04132576 0,09409025 ! purine salvage GO:0043101 12 8 0,000 0,04132576 0,09400264 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04132576 0,0939152 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04132576 0,09382792 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04132576 0,0937408 ! osteoblast development GO:0002076 17 8 0,000 0,04132576 0,09365384 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04132576 0,09356704 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04132576 0,09348041 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04132576 0,09339393 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04132576 0,09330761 ! response to UV-B GO:0010224 17 8 0,000 0,04132576 0,09322146 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04132576 0,09313546 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04132576 0,09304962 ! intermediate filament organization GO:0045109 12 8 0,000 0,04132576 0,09296394 ! cellular extravasation GO:0045123 13 8 0,000 0,04132576 0,09287842 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04132576 0,09279305 ! response to antibiotic GO:0046677 11 8 0,000 0,04132576 0,09270784 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04132576 0,09262279 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04132576 0,09253789 ! DNA topological change GO:0006265 12 8 0,000 0,04132576 0,09245315 ! response to tropane GO:0014073 15 8 0,000 0,04132576 0,09236856 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04132576 0,09228413 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04132576 0,09219985 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04132576 0,09211573 ! mast cell activation GO:0045576 14 8 0,000 0,04132576 0,09203176 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04132576 0,09194794 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04132576 0,09186427 ! gas homeostasis GO:0033483 14 8 0,000 0,04132576 0,09178076 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04132576 0,0916974 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04132576 0,09161419 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04132576 0,09153113 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04132576 0,09144822 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04132576 0,09136546 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04132576 0,09128286 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04132576 0,0912004 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04132576 0,09111808 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04132576 0,09103592 ! response to tumor cell GO:0002347 16 8 0,000 0,04132576 0,09095391 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04132576 0,09087204 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04132576 0,09079032 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04132576 0,09070875 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04132576 0,09062732 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04132576 0,09054604 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04132576 0,09046491 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04132576 0,09038392 ! hormone catabolic process GO:0042447 17 8 0,000 0,04132576 0,09030308 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04132576 0,09022238 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04132576 0,09014182 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04132576 0,09006141 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04132576 0,08998114 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04132576 0,08990101 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04132576 0,08982103 ! adult feeding behavior GO:0008343 10 8 0,000 0,04132576 0,08974119 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04132576 0,08966149 ! ATP catabolic process GO:0006200 11 8 0,000 0,04132576 0,08958193 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04132576 0,08950252 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04132576 0,08942324 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04132576 0,0893441 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04132576 0,08926511 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04132576 0,08918625 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04132576 0,08910754 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04132576 0,08902896 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04132576 0,08895052 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04132576 0,08887222 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04132576 0,08879405 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04132576 0,08871603 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04132576 0,08863814 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04132576 0,08856038 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04132576 0,08848277 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04132576 0,08840529 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04132576 0,08832794 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04132576 0,08825073 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04132576 0,08817366 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04132576 0,08809672 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04132576 0,08801991 ! viral reproductive process GO:0022415 132 62 1,000 0,04237139 0,09016838 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,04237139 0,09008991 ! regulation of mitosis GO:0007088 112 63 1,000 0,04361263 0,09264839 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,04486731 0,09523096 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,04613526 0,09783718 ! axon extension GO:0048675 16 9 0,000 0,04637056 0,0982509 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04637056 0,09816576 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04637056 0,09808077 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04637056 0,09799592 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04637056 0,09791123 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04637056 0,09782667 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04637056 0,09774227 ! reproductive behavior GO:0019098 22 9 0,000 0,04637056 0,09765801 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04637056 0,09757389 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04637056 0,09748992 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04637056 0,0974061 ! UTP metabolic process GO:0046051 10 9 0,000 0,04637056 0,09732241 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04637056 0,09723887 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04637056 0,09715548 ! artery development GO:0060840 25 9 0,000 0,04637056 0,09707223 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04637056 0,09698912 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04637056 0,09690615 ! equilibrioception GO:0050957 20 9 0,000 0,04637056 0,09682332 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04637056 0,09674064 ! chemosensory behavior GO:0007635 21 9 0,000 0,04637056 0,0966581 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04637056 0,09657569 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04637056 0,09649343 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04637056 0,09641131 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04637056 0,09632933 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04637056 0,09624748 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04637056 0,09616578 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04637056 0,09608421 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04637056 0,09600279 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04637056 0,0959215 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04637056 0,09584035 ! protein targeting to ER GO:0045047 25 9 0,000 0,04637056 0,09575933 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04637056 0,09567845 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04637056 0,09559771 ! T cell selection GO:0045058 27 9 0,000 0,04637056 0,09551711 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04637056 0,09543664 ! glycine catabolic process GO:0006546 15 9 0,000 0,04637056 0,0953563 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04637056 0,09527611 ! endosome organization GO:0007032 20 9 0,000 0,04637056 0,09519604 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04637056 0,09511611 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04637056 0,09503632 ! mannose metabolic process GO:0006013 13 9 0,000 0,04637056 0,09495665 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04637056 0,09487713 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04637056 0,09479773 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04637056 0,09471847 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04637056 0,09463934 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04637056 0,09456034 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04637056 0,09448148 ! retinol metabolic process GO:0042572 20 9 0,000 0,04637056 0,09440274 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04637056 0,09432414 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04637056 0,09424566 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04637056 0,09416732 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04637056 0,09408911 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04637056 0,09401103 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04637056 0,09393308 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04637056 0,09385525 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04637056 0,09377756 ! response to amine stimulus GO:0014075 13 9 0,000 0,04637056 0,09369999 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04637056 0,09362255 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04637056 0,09354524 ! erythrocyte development GO:0048821 17 9 0,000 0,04637056 0,09346806 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04637056 0,09339101 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04637056 0,09331408 ! renal water homeostasis GO:0003091 15 9 0,000 0,04637056 0,09323728 ! postreplication repair GO:0006301 25 9 0,000 0,04637056 0,0931606 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04637056 0,09308405 ! icosanoid secretion GO:0032309 15 9 0,000 0,04637056 0,09300763 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04637056 0,09293133 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04637056 0,09285516 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04637056 0,09277911 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04637056 0,09270318 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04637056 0,09262738 ! sterol catabolic process GO:0016127 14 9 0,000 0,04637056 0,09255171 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04637056 0,09247615 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04637056 0,09240073 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04637056 0,09232542 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04637056 0,09225024 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04637056 0,09217517 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04637056 0,09210024 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04637056 0,09202542 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04637056 0,09195072 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04637056 0,09187615 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04637056 0,09180169 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04637056 0,09172736 ! purine base metabolic process GO:0006144 25 9 0,000 0,04637056 0,09165315 ! pigment granule transport GO:0051904 17 9 0,000 0,04637056 0,09157905 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04637056 0,09150508 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04637056 0,09143123 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04637056 0,09135749 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04637056 0,09128388 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04637056 0,09121038 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04637056 0,091137 ! mitochondrion localization GO:0051646 18 9 0,000 0,04637056 0,09106374 ! gonad development GO:0008406 115 66 1,000 0,04741631 0,0930426 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05001701 0,09806706 ! detection of external stimulus GO:0009581 102 68 1,000 0,05001701 0,09798842 ! viral reproduction GO:0016032 142 68 1,000 0,05001701 0,0979099 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05001701 0,09783151 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,05001701 0,09775324 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05133633 0,10025152 ! developmental maturation GO:0021700 128 69 1,000 0,05133633 0,10017144 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05138896 0,10019412 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05138896 0,10011422 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05138896 0,10003445 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05138896 0,0999548 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05138896 0,09987528 ! associative learning GO:0008306 21 10 0,000 0,05138896 0,09979589 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05138896 0,09971662 ! phosphate transport GO:0006817 24 10 0,000 0,05138896 0,09963748 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05138896 0,09955847 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05138896 0,09947958 ! CTP metabolic process GO:0046036 11 10 0,000 0,05138896 0,09940082 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05138896 0,09932218 ! GTP metabolic process GO:0046039 11 10 0,000 0,05138896 0,09924366 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05138896 0,09916527 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05138896 0,099087 ! social behavior GO:0035176 29 10 0,000 0,05138896 0,09900886 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05138896 0,09893084 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05138896 0,09885294 ! androgen metabolic process GO:0008209 17 10 0,000 0,05138896 0,09877516 ! phospholipid efflux GO:0033700 19 10 0,000 0,05138896 0,09869751 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05138896 0,09861998 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05138896 0,09854257 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05138896 0,09846528 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05138896 0,09838811 ! lung alveolus development GO:0048286 26 10 0,000 0,05138896 0,09831107 ! pathogenesis GO:0009405 17 10 0,000 0,05138896 0,09823414 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05138896 0,09815733 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05138896 0,09808065 ! endoderm development GO:0007492 18 10 0,000 0,05138896 0,09800408 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05138896 0,09792764 ! arginine catabolic process GO:0006527 17 10 0,000 0,05138896 0,09785131 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05138896 0,0977751 ! proline metabolic process GO:0006560 13 10 0,000 0,05138896 0,09769901 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05138896 0,09762304 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05138896 0,09754719 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05138896 0,09747145 ! V(D)J recombination GO:0033151 34 10 0,000 0,05138896 0,09739583 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05138896 0,09732033 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05138896 0,09724495 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05138896 0,09716968 ! B cell proliferation GO:0042100 19 10 0,000 0,05138896 0,09709453 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05138896 0,0970195 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05138896 0,09694458 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05138896 0,09686978 ! ruffle organization GO:0031529 17 10 0,000 0,05138896 0,09679509 ! epithelial cell development GO:0002064 21 10 0,000 0,05138896 0,09672052 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05138896 0,09664606 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05138896 0,09657172 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05138896 0,09649749 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05138896 0,09642337 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05138896 0,09634937 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05138896 0,09627548 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05138896 0,09620171 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05138896 0,09612805 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05138896 0,0960545 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05138896 0,09598106 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05138896 0,09590774 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05138896 0,09583453 ! segment specification GO:0007379 15 10 0,000 0,05138896 0,09576143 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05138896 0,09568844 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05138896 0,09561556 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05138896 0,09554279 ! response to dsRNA GO:0043331 23 10 0,000 0,05138896 0,09547014 ! DNA ligation GO:0006266 18 10 0,000 0,05138896 0,09539759 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05138896 0,09532516 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05138896 0,09525283 ! melanosome localization GO:0032400 16 10 0,000 0,05138896 0,09518061 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05138896 0,09510851 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05138896 0,09503651 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05138896 0,09496462 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05138896 0,09489284 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05138896 0,09482117 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05138896 0,09474961 ! protein sumoylation GO:0016925 17 10 0,000 0,05138896 0,09467815 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05138896 0,09460681 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05138896 0,09453557 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05138896 0,09446443 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05138896 0,09439341 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05138896 0,09432249 ! salivary gland development GO:0007431 28 10 0,000 0,05138896 0,09425167 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05138896 0,09418097 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05138896 0,09411037 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05138896 0,09403987 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05138896 0,09396948 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05138896 0,0938992 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05138896 0,09382902 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05138896 0,09375895 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05138896 0,09368898 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05138896 0,09361911 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05138896 0,09354935 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05138896 0,0934797 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05138896 0,09341014 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05138896 0,09334069 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05138896 0,09327135 ! blastocyst formation GO:0001825 18 10 0,000 0,05138896 0,0932021 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05138896 0,09313296 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05138896 0,09306392 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05138896 0,09299499 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05138896 0,09292615 ! response to nicotine GO:0035094 20 10 0,000 0,05138896 0,09285742 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05138896 0,09278879 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05138896 0,09272026 ! germ cell development GO:0007281 133 70 1,000 0,05266806 0,09495799 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,05401206 0,09730933 ! actin filament organization GO:0007015 167 72 1,000 0,05536814 0,09967897 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,05536814 0,09960557 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,05536814 0,09953228 ! respiratory burst GO:0045730 17 11 0,000 0,05638109 0,10127868 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05638109 0,10120426 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05638109 0,10112996 ! thyroid gland development GO:0030878 26 11 0,000 0,05638109 0,10105576 ! synapsis GO:0007129 14 11 0,000 0,05638109 0,10098167 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05638109 0,10090769 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05638109 0,10083382 ! response to pain GO:0048265 27 11 0,000 0,05638109 0,10076006 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05638109 0,1006864 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05638109 0,10061286 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05638109 0,10053942 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05638109 0,10046608 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05638109 0,10039286 ! bone resorption GO:0045453 16 11 0,000 0,05638109 0,10031974 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05638109 0,10024672 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05638109 0,10017382 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05638109 0,10010102 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05638109 0,10002832 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05638109 0,09995573 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05638109 0,09988325 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05638109 0,09981087 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05638109 0,09973859 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05638109 0,09966642 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05638109 0,09959436 ! UV protection GO:0009650 20 11 0,000 0,05638109 0,0995224 ! adult heart development GO:0007512 16 11 0,000 0,05638109 0,09945054 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05638109 0,09937879 ! macroautophagy GO:0016236 19 11 0,000 0,05638109 0,09930714 ! temperature homeostasis GO:0001659 18 11 0,000 0,05638109 0,09923559 ! behavioral fear response GO:0001662 27 11 0,000 0,05638109 0,09916415 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05638109 0,0990928 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05638109 0,09902157 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05638109 0,09895043 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05638109 0,0988794 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05638109 0,09880846 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05638109 0,09873763 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05638109 0,0986669 ! regulation of organ growth GO:0046620 14 11 0,000 0,05638109 0,09859628 ! pigment granule localization GO:0051875 20 11 0,000 0,05638109 0,09852575 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05638109 0,09845532 ! vasoconstriction GO:0042310 20 11 0,000 0,05638109 0,098385 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05638109 0,09831477 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05638109 0,09824465 ! embryonic axis specification GO:0000578 19 11 0,000 0,05638109 0,09817462 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05638109 0,0981047 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05638109 0,09803487 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05638109 0,09796515 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05638109 0,09789552 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05638109 0,09782599 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05638109 0,09775656 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05638109 0,09768723 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05638109 0,097618 ! prophase GO:0051324 17 11 0,000 0,05638109 0,09754887 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05638109 0,09747983 ! nucleosome positioning GO:0016584 15 11 0,000 0,05638109 0,09741089 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05638109 0,09734205 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05638109 0,0972733 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05638109 0,09720466 ! apical protein localization GO:0045176 18 11 0,000 0,05638109 0,09713611 ! acid secretion GO:0046717 20 11 0,000 0,05638109 0,09706765 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05638109 0,09699929 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05638109 0,09693103 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05638109 0,09686287 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05638109 0,0967948 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05638109 0,09672682 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05638109 0,09665895 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05638109 0,09659116 ! cholesterol efflux GO:0033344 21 11 0,000 0,05638109 0,09652347 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05638109 0,09645588 ! germ cell migration GO:0008354 26 11 0,000 0,05638109 0,09638838 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05638109 0,09632098 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05638109 0,09625367 ! activation of innate immune response GO:0002218 16 11 0,000 0,05638109 0,09618645 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05638109 0,09611933 ! lysogeny GO:0030069 22 11 0,000 0,05638109 0,0960523 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05638109 0,09598536 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05638109 0,09591852 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05638109 0,09585177 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05638109 0,09578512 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,05950731 0,10102596 ! axon guidance GO:0007411 162 75 1,000 0,05950731 0,1009558 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,06091014 0,10326403 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06134708 0,10393268 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06134708 0,10386066 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06134708 0,10378873 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06134708 0,1037169 ! virus-host interaction GO:0019048 30 12 0,000 0,06134708 0,10364518 ! mating GO:0007618 17 12 0,000 0,06134708 0,10357355 ! protein complex disassembly GO:0043241 28 12 0,000 0,06134708 0,10350202 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 29 12 0,000 0,06134708 0,10343059 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06134708 0,10335926 ! T cell proliferation GO:0042098 32 12 0,000 0,06134708 0,10328803 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06134708 0,10321689 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06134708 0,10314585 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06134708 0,10307492 ! drug transport GO:0015893 16 12 0,000 0,06134708 0,10300407 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06134708 0,10293333 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06134708 0,10286268 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06134708 0,10279213 ! focal adhesion formation GO:0048041 37 12 0,000 0,06134708 0,10272168 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06134708 0,10265132 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06134708 0,10258106 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06134708 0,10251089 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 21 12 0,000 0,06134708 0,10244083 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06134708 0,10237085 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06134708 0,10230097 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06134708 0,10223119 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06134708 0,1021615 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06134708 0,10209191 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06134708 0,10202241 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06134708 0,10195301 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06134708 0,1018837 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06134708 0,10181449 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06134708 0,10174537 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06134708 0,10167634 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06134708 0,10160741 ! fucose catabolic process GO:0019317 25 12 0,000 0,06134708 0,10153857 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06134708 0,10146982 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06134708 0,10140117 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06134708 0,10133261 ! zymogen activation GO:0031638 18 12 0,000 0,06134708 0,10126414 ! T cell homeostasis GO:0043029 28 12 0,000 0,06134708 0,10119576 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06134708 0,10112748 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06134708 0,10105929 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06134708 0,10099119 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06134708 0,10092318 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06134708 0,10085527 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06134708 0,10078744 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06134708 0,10071971 ! embryonic placenta development GO:0001892 21 12 0,000 0,06134708 0,10065207 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06134708 0,10058451 ! response to cold GO:0009409 17 12 0,000 0,06134708 0,10051705 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06134708 0,10044968 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06134708 0,1003824 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06232426 0,10191309 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,06232426 0,10184492 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06374951 0,10410431 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,06518574 0,1063786 ! protein oligomerization GO:0051259 149 79 1,000 0,06518574 0,10630759 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06628708 0,10803159 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06628708 0,10795957 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06628708 0,10788764 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06628708 0,10781581 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06628708 0,10774408 ! peroxisomal transport GO:0043574 28 13 0,000 0,06628708 0,10767244 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06628708 0,1076009 ! cartilage condensation GO:0001502 22 13 0,000 0,06628708 0,10752945 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06628708 0,10745809 ! organelle fusion GO:0048284 36 13 0,000 0,06628708 0,10738684 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06628708 0,10731567 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06628708 0,1072446 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06628708 0,10717363 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06628708 0,10710274 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06628708 0,10703196 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06628708 0,10696126 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06628708 0,10689066 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06628708 0,10682015 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06628708 0,10674974 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06628708 0,10667941 ! methionine metabolic process GO:0006555 31 13 0,000 0,06628708 0,10660918 ! plasma membrane organization GO:0007009 27 13 0,000 0,06628708 0,10653904 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06628708 0,106469 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06628708 0,10639905 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06628708 0,10632918 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06628708 0,10625941 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,06628708 0,10618974 ! exocrine system development GO:0035272 34 13 0,000 0,06628708 0,10612015 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06628708 0,10605065 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06628708 0,10598125 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06628708 0,10591193 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06628708 0,10584271 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06628708 0,10577358 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06628708 0,10570454 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06628708 0,10563558 ! protein homotetramerization GO:0051289 24 13 0,000 0,06628708 0,10556672 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06628708 0,10549795 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06628708 0,10542926 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06628708 0,10536067 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06628708 0,10529216 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06628708 0,10522375 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06628708 0,10515542 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06628708 0,10508718 ! histone methylation GO:0016571 29 13 0,000 0,06628708 0,10501903 ! chromatin silencing GO:0006342 29 13 0,000 0,06628708 0,10495097 ! gland morphogenesis GO:0022612 31 13 0,000 0,06628708 0,104883 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06628708 0,10481511 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06628708 0,10474731 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06628708 0,1046796 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06628708 0,10461198 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06628708 0,10454445 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06628708 0,104477 ! spleen development GO:0048536 24 13 0,000 0,06628708 0,10440964 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06628708 0,10434236 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06628708 0,10427518 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06628708 0,10420807 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06628708 0,10414106 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06628708 0,10407413 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06628708 0,10400729 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06628708 0,10394053 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06628708 0,10387386 ! insulin secretion GO:0030073 24 13 0,000 0,06628708 0,10380727 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06628708 0,10374077 ! acrosome reaction GO:0007340 19 13 0,000 0,06628708 0,10367436 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06628708 0,10360803 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06628708 0,10354178 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0666328 0,10401529 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,0666328 0,10394887 ! muscle cell differentiation GO:0042692 178 81 1,000 0,06809053 0,10615517 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,06809053 0,10608747 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,06955878 0,10830599 ! protein import into nucleus GO:0006606 174 82 1,000 0,06955878 0,108237 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,0710374 0,11046746 ! response to drug GO:0042493 149 83 1,000 0,0710374 0,11039719 ! nuclear import GO:0051170 177 83 1,000 0,0710374 0,110327 ! rRNA transcription GO:0009303 28 14 0,000 0,07120122 0,11051118 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07120122 0,11044101 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,07120122 0,11037093 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07120122 0,11030095 ! non-recombinational repair GO:0000726 29 14 0,000 0,07120122 0,11023105 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07120122 0,11016124 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07120122 0,11009151 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07120122 0,11002188 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07120122 0,10995233 ! lipid localization GO:0010876 32 14 0,000 0,07120122 0,10988288 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07120122 0,10981351 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07120122 0,10974422 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07120122 0,10967503 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07120122 0,10960592 ! arginine metabolic process GO:0006525 21 14 0,000 0,07120122 0,1095369 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07120122 0,10946796 ! regulation of heart rate GO:0002027 25 14 0,000 0,07120122 0,10939911 ! fear response GO:0042596 34 14 0,000 0,07120122 0,10933035 ! organic alcohol transport GO:0015850 29 14 0,000 0,07120122 0,10926168 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07120122 0,10919309 ! embryo implantation GO:0007566 30 14 0,000 0,07120122 0,10912459 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07120122 0,10905617 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07120122 0,10898784 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07120122 0,10891959 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07120122 0,10885143 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07120122 0,10878336 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07120122 0,10871537 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07120122 0,10864747 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07120122 0,10857965 ! ribosome assembly GO:0042255 18 14 0,000 0,07120122 0,10851191 ! cerebellum development GO:0021549 23 14 0,000 0,07120122 0,10844426 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07120122 0,10837669 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07120122 0,10830921 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07120122 0,10824181 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07120122 0,1081745 ! NADP metabolic process GO:0006739 24 14 0,000 0,07120122 0,10810727 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07120122 0,10804012 ! oxygen transport GO:0015671 22 14 0,000 0,07120122 0,10797306 ! male genitalia development GO:0030539 26 14 0,000 0,07120122 0,10790607 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07120122 0,10783918 ! regulation of axon extension GO:0030516 43 14 0,000 0,07120122 0,10777236 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,07120122 0,10770563 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07120122 0,10763898 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07120122 0,10757241 ! regulation of ligase activity GO:0051340 147 84 1,000 0,07252625 0,10950657 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,07402518 0,11170074 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,07402518 0,11163179 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,07402518 0,11156293 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,07553403 0,11376673 ! regulation of lyase activity GO:0051339 169 86 1,000 0,07553403 0,11369664 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07553403 0,11362663 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07608964 0,11439199 ! lactation GO:0007595 30 15 0,000 0,07608964 0,11432164 ! reproductive cellular process GO:0048610 22 15 0,000 0,07608964 0,11425138 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07608964 0,1141812 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07608964 0,1141111 ! superoxide anion generation GO:0042554 22 15 0,000 0,07608964 0,1140411 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07608964 0,11397118 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07608964 0,11390134 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07608964 0,11383159 ! copper ion transport GO:0006825 22 15 0,000 0,07608964 0,11376193 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07608964 0,11369235 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07608964 0,11362285 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07608964 0,11355344 ! sulfate transport GO:0008272 27 15 0,000 0,07608964 0,11348412 ! response to cAMP GO:0051591 25 15 0,000 0,07608964 0,11341488 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07608964 0,11334573 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07608964 0,11327665 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07608964 0,11320767 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07608964 0,11313876 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07608964 0,11306994 ! vesicle coating GO:0006901 38 15 0,000 0,07608964 0,11300121 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07608964 0,11293256 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07608964 0,11286399 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07608964 0,1127955 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07608964 0,1127271 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07608964 0,11265878 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07608964 0,11259054 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07608964 0,11252239 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07608964 0,11245432 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07608964 0,11238633 ! histone deacetylation GO:0016575 24 15 0,000 0,07608964 0,11231842 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07608964 0,1122506 ! water homeostasis GO:0030104 28 15 0,000 0,07608964 0,11218285 ! cofactor transport GO:0051181 30 15 0,000 0,07608964 0,11211519 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07608964 0,11204761 ! muscle maintenance GO:0046716 26 15 0,000 0,07608964 0,11198011 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07608964 0,1119127 ! intestinal absorption GO:0050892 31 15 0,000 0,07608964 0,11184536 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07608964 0,11177811 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07608964 0,11171093 ! cell killing GO:0001906 32 15 0,000 0,07608964 0,11164384 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07608964 0,11157682 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07608964 0,11150989 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07608964 0,11144304 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07608964 0,11137627 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07608964 0,11130957 ! actin filament polymerization GO:0030041 27 15 0,000 0,07608964 0,11124296 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07608964 0,11117643 ! amine biosynthetic process GO:0009309 146 88 1,000 0,07858096 0,11474793 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08011874 0,11692359 ! protein localization in nucleus GO:0034504 192 89 1,000 0,08011874 0,11685379 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08095246 0,11799932 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08095246 0,11792896 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08095246 0,11785868 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08095246 0,11778848 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08095246 0,11771837 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08095246 0,11764834 ! bone remodeling GO:0046849 28 16 0,000 0,08095246 0,1175784 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08095246 0,11750854 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08095246 0,11743876 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08095246 0,11736906 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08095246 0,11729945 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08095246 0,11722991 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08095246 0,11716047 ! startle response GO:0001964 28 16 0,000 0,08095246 0,1170911 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08095246 0,11702181 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08095246 0,11695261 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08095246 0,11688349 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08095246 0,11681445 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08095246 0,11674549 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08095246 0,11667662 ! response to osmotic stress GO:0006970 27 16 0,000 0,08095246 0,11660782 ! lysosomal transport GO:0007041 31 16 0,000 0,08095246 0,11653911 ! fructose metabolic process GO:0006000 25 16 0,000 0,08095246 0,11647047 ! L-amino acid transport GO:0015807 33 16 0,000 0,08095246 0,11640192 ! stem cell development GO:0048864 46 16 0,000 0,08095246 0,11633345 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08095246 0,11626506 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08095246 0,11619675 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08095246 0,11612852 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08095246 0,11606037 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08095246 0,1159923 ! axon cargo transport GO:0008088 46 16 0,000 0,08095246 0,11592431 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08095246 0,11585639 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08095246 0,11578856 ! DNA replication initiation GO:0006270 28 16 0,000 0,08095246 0,11572081 ! neuron recognition GO:0008038 40 16 0,000 0,08095246 0,11565314 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08095246 0,11558554 ! tissue regeneration GO:0042246 27 16 0,000 0,08095246 0,11551803 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08095246 0,11545059 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08095246 0,11538324 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08095246 0,11531596 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08095246 0,11524876 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08095246 0,11518163 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08095246 0,11511459 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08095246 0,11504762 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08095246 0,11498074 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08095246 0,11491393 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08095246 0,11484719 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08095246 0,11478054 ! peptide hormone processing GO:0016486 27 16 0,000 0,08095246 0,11471396 ! response to unfolded protein GO:0006986 139 90 1,000 0,08166589 0,11565784 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,08322225 0,11779372 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 1,000 0,08322225 0,11772552 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0847877 0,11987058 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08578983 0,12121721 ! metencephalon development GO:0022037 32 17 0,000 0,08578983 0,12114714 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08578983 0,12107715 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,08578983 0,12100724 ! endothelial cell migration GO:0043542 31 17 0,000 0,08578983 0,12093742 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08578983 0,12086767 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08578983 0,12079801 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08578983 0,12072843 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08578983 0,12065892 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08578983 0,1205895 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08578983 0,12052015 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08578983 0,12045089 ! myoblast differentiation GO:0045445 50 17 0,000 0,08578983 0,1203817 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08578983 0,1203126 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08578983 0,12024357 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,08578983 0,12017463 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08578983 0,12010576 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08578983 0,12003697 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08578983 0,11996826 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08578983 0,11989963 ! NAD metabolic process GO:0019674 33 17 0,000 0,08578983 0,11983107 ! membrane budding GO:0006900 42 17 0,000 0,08578983 0,1197626 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08578983 0,1196942 ! regulation of protein binding GO:0043393 33 17 0,000 0,08578983 0,11962588 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08578983 0,11955764 ! genitalia development GO:0048806 32 17 0,000 0,08578983 0,11948948 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08578983 0,11942139 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,08578983 0,11935339 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08578983 0,11928546 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08578983 0,1192176 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08578983 0,11914983 ! steroid catabolic process GO:0006706 34 17 0,000 0,08578983 0,11908213 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08578983 0,11901451 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08578983 0,11894696 ! gas transport GO:0015669 26 17 0,000 0,08578983 0,11887949 ! organic cation transport GO:0015695 32 17 0,000 0,08578983 0,1188121 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08578983 0,11874479 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08578983 0,11867755 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08578983 0,11861038 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,08636209 0,11933404 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,08636209 0,11926659 GO:0010498|proteasomal protein catabolic process, ! vitamin metabolic process GO:0006766 153 93 1,000 0,08636209 0,1191992 ! sterol metabolic process GO:0016125 166 94 1,000 0,08794529 0,12131583 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,08953716 0,12344203 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09060187 0,12483946 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09060187 0,12476909 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09060187 0,12469879 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09060187 0,12462858 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09060187 0,12455845 ! adult walking behavior GO:0007628 36 18 0,000 0,09060187 0,12448839 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09060187 0,12441841 ! heart looping GO:0001947 34 18 0,000 0,09060187 0,12434852 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09060187 0,1242787 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09060187 0,12420896 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09060187 0,12413929 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09060187 0,12406971 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09060187 0,1240002 ! glycine metabolic process GO:0006544 30 18 0,000 0,09060187 0,12393077 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09060187 0,12386142 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,09060187 0,12379215 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09060187 0,12372295 ! DNA integration GO:0015074 32 18 0,000 0,09060187 0,12365383 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09060187 0,12358479 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09060187 0,12351583 ! neural crest cell migration GO:0001755 41 18 0,000 0,09060187 0,12344694 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09060187 0,12337813 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09060187 0,12330939 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09060187 0,12324073 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09060187 0,12317215 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09060187 0,12310365 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09060187 0,12303522 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,09060187 0,12296687 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09060187 0,12289859 ! detection of bacterium GO:0016045 22 18 0,000 0,09060187 0,12283039 ! defense response to virus GO:0051607 43 18 0,000 0,09060187 0,12276226 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09060187 0,12269421 ! response to protein stimulus GO:0051789 158 96 1,000 0,09113757 0,12335129 ! regulation of T cell activation GO:0050863 175 96 1,000 0,09113757 0,12328299 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,09274639 0,12538983 ! transcription initiation GO:0006352 171 97 1,000 0,09274639 0,12532048 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,09436348 0,12743503 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09538871 0,12874841 ! positive regulation of translation GO:0045727 31 19 0,000 0,09538871 0,12867732 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09538871 0,1286063 ! neuron maturation GO:0042551 46 19 0,000 0,09538871 0,12853537 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09538871 0,12846451 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09538871 0,12839373 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09538871 0,12832303 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09538871 0,12825241 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09538871 0,12818186 ! inositol metabolic process GO:0006020 33 19 0,000 0,09538871 0,12811139 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09538871 0,128041 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09538871 0,12797069 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09538871 0,12790045 ! pigmentation during development GO:0048066 42 19 0,000 0,09538871 0,12783029 ! heme metabolic process GO:0042168 40 19 0,000 0,09538871 0,12776021 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09538871 0,1276902 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09538871 0,12762027 ! peptide cross-linking GO:0018149 39 19 0,000 0,09538871 0,12755042 ! protein export from nucleus GO:0006611 40 19 0,000 0,09538871 0,12748065 ! heart process GO:0003015 32 19 0,000 0,09538871 0,12741095 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09538871 0,12734132 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09538871 0,12727178 ! visual learning GO:0008542 38 19 0,000 0,09538871 0,1272023 ! cellular pigmentation GO:0033059 37 19 0,000 0,09538871 0,12713291 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09538871 0,12706359 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09538871 0,12699434 ! vitamin transport GO:0051180 31 19 0,000 0,09538871 0,12692517 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09538871 0,12685608 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09538871 0,12678706 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09538871 0,12671812 ! cilium assembly GO:0042384 38 19 0,000 0,09538871 0,12664925 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09538871 0,12658046 ! protein secretion GO:0009306 45 20 0,000 0,10015049 0,13282717 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10015049 0,1327551 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10015049 0,13268311 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10015049 0,13261119 ! skin development GO:0043588 42 20 0,000 0,10015049 0,13253936 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10015049 0,1324676 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10015049 0,13239592 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10015049 0,13232431 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10015049 0,13225279 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,10015049 0,13218134 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,10015049 0,13210996 ! response to alkaloid GO:0043279 38 20 0,000 0,10015049 0,13203867 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10015049 0,13196745 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,10015049 0,13189631 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,10015049 0,13182524 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10015049 0,13175426 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,10015049 0,13168334 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,10015049 0,13161251 ! body fluid secretion GO:0007589 33 20 0,000 0,10015049 0,13154175 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10015049 0,13147107 ! peptide secretion GO:0002790 38 20 0,000 0,10015049 0,13140046 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10015049 0,13132993 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10015049 0,13125947 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10015049 0,13118909 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10015049 0,13111879 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10015049 0,13104856 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,10015049 0,1309784 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10015049 0,13090832 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10015049 0,13083832 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10015049 0,13076839 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10015049 0,13069853 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10015049 0,13062875 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10015049 0,13055905 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10015049 0,13048942 ! regulation of cell killing GO:0031341 46 21 0,000 0,10488734 0,13658837 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10488734 0,1365156 ! hormone secretion GO:0046879 39 21 0,000 0,10488734 0,13644291 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10488734 0,13637029 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10488734 0,13629775 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10488734 0,13622529 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10488734 0,13615291 ! ovarian follicle development GO:0001541 39 21 0,000 0,10488734 0,1360806 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10488734 0,13600838 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10488734 0,13593622 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,10488734 0,13586415 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10488734 0,13579215 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10488734 0,13572022 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10488734 0,13564837 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10488734 0,1355766 ! sensory perception of pain GO:0019233 33 21 0,000 0,10488734 0,13550491 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10488734 0,13543329 ! collagen fibril organization GO:0030199 62 21 0,000 0,10488734 0,13536174 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10488734 0,13529027 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10488734 0,13521888 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10488734 0,13514756 ! collagen catabolic process GO:0030574 29 21 0,000 0,10488734 0,13507632 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10488734 0,13500515 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,10488734 0,13493406 ! actin filament-based movement GO:0030048 47 21 0,000 0,10488734 0,13486304 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10959939 0,14084761 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10959939 0,14077356 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10959939 0,14069959 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10959939 0,14062569 ! microtubule-based transport GO:0010970 59 22 0,000 0,10959939 0,14055187 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,10959939 0,14047813 ! cellular response to starvation GO:0009267 37 22 0,000 0,10959939 0,14040446 ! vacuolar transport GO:0007034 41 22 0,000 0,10959939 0,14033088 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10959939 0,14025737 ! fucose metabolic process GO:0006004 44 22 0,000 0,10959939 0,14018393 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,10959939 0,14011058 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10959939 0,1400373 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,10959939 0,13996409 ! stem cell differentiation GO:0048863 57 22 0,000 0,10959939 0,13989097 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10959939 0,13981792 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,10959939 0,13974494 ! cytolysis GO:0019835 27 22 0,000 0,10959939 0,13967205 ! renal system process GO:0003014 42 22 0,000 0,10959939 0,13959922 ! vasodilation GO:0042311 40 22 0,000 0,10959939 0,13952648 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10959939 0,13945381 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10959939 0,13938121 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10959939 0,13930869 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,10959939 0,13923625 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10959939 0,13916388 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10959939 0,13909159 ! sarcomere organization GO:0045214 32 22 0,000 0,10959939 0,13901937 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,10959939 0,13894723 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,10959939 0,13887516 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10959939 0,13880317 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10959939 0,13873125 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10959939 0,1386594 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,10959939 0,13858764 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10959939 0,13851594 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,11428676 0,14436534 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11428676 0,14429073 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11428676 0,1442162 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11428676 0,14414175 ! gluconeogenesis GO:0006094 38 23 0,000 0,11428676 0,14406737 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11428676 0,14399307 ! viral genome replication GO:0019079 44 23 0,000 0,11428676 0,14391885 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11428676 0,1438447 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11428676 0,14377063 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11428676 0,14369664 ! regeneration GO:0031099 42 23 0,000 0,11428676 0,14362272 ! axis specification GO:0009798 43 23 0,000 0,11428676 0,14354888 ! visual behavior GO:0007632 46 23 0,000 0,11428676 0,14347511 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,11428676 0,14340142 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11428676 0,14332781 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11428676 0,14325427 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,11428676 0,1431808 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11428676 0,14310742 ! peroxisome organization GO:0007031 43 23 0,000 0,11428676 0,1430341 ! lysosome organization GO:0007040 47 23 0,000 0,11428676 0,14296086 ! vesicle targeting GO:0006903 49 23 0,000 0,11428676 0,1428877 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,11428676 0,14281461 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11428676 0,1427416 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11428676 0,14266866 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11428676 0,1425958 ! DNA modification GO:0006304 36 23 0,000 0,11428676 0,142523 ! fatty acid transport GO:0015908 47 23 0,000 0,11428676 0,14245029 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11428676 0,14237765 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11428676 0,14230508 ! hormone transport GO:0009914 41 23 0,000 0,11428676 0,14223259 ! cell-cell recognition GO:0009988 28 23 0,000 0,11428676 0,14216017 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11428676 0,14208782 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11428676 0,14201555 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11428676 0,14194335 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11894959 0,14765948 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11894959 0,14758449 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,11894959 0,14750957 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,11894959 0,14743473 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11894959 0,14735997 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11894959 0,14728528 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11894959 0,14721067 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11894959 0,14713613 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11894959 0,14706167 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11894959 0,14698728 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11894959 0,14691297 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11894959 0,14683874 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11894959 0,14676458 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11894959 0,14669049 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11894959 0,14661648 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,11894959 0,14654254 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11894959 0,14646868 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11894959 0,14639489 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11894959 0,14632118 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11894959 0,14624754 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11894959 0,14617397 ! membrane depolarization GO:0051899 45 24 0,000 0,11894959 0,14610048 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11894959 0,14602707 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11894959 0,14595372 ! platelet activation GO:0030168 41 24 0,000 0,11894959 0,14588045 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11894959 0,14580726 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11894959 0,14573413 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11894959 0,14566108 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11894959 0,14558811 ! regulation of amine transport GO:0051952 41 24 0,000 0,11894959 0,1455152 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12358801 0,15111387 ! leukocyte adhesion GO:0007159 55 25 0,000 0,12358801 0,15103827 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12358801 0,15096275 ! keratinization GO:0031424 37 25 0,000 0,12358801 0,15088731 ! vasculogenesis GO:0001570 49 25 0,000 0,12358801 0,15081194 ! vacuole organization GO:0007033 49 25 0,000 0,12358801 0,15073665 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12358801 0,15066143 ! chromosome condensation GO:0030261 48 25 0,000 0,12358801 0,15058629 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12358801 0,15051122 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12358801 0,15043622 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12358801 0,15036131 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12358801 0,15028646 ! immunoglobulin production GO:0002377 62 25 0,000 0,12358801 0,15021169 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12358801 0,150137 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,12358801 0,15006238 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12358801 0,14998783 ! liver development GO:0001889 55 25 0,000 0,12358801 0,14991336 ! protein tetramerization GO:0051262 57 25 0,000 0,12358801 0,14983896 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12820213 0,15535605 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12820213 0,15527903 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12820213 0,15520208 ! molting cycle process GO:0022404 52 26 0,000 0,12820213 0,15512521 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12820213 0,15504842 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12820213 0,1549717 GO:0006479|protein amino acid methylation, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12820213 0,15489506 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12820213 0,15481849 ! digestive system process GO:0022600 49 26 0,000 0,12820213 0,154742 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12820213 0,15466558 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,12820213 0,15458924 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12820213 0,15451298 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12820213 0,15443679 ! neural crest cell development GO:0014032 59 26 0,000 0,12820213 0,15436067 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12820213 0,15428463 ! negative regulation of cell development GO:0010721 83 26 0,000 0,12820213 0,15420867 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12820213 0,15413278 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12820213 0,15405696 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12820213 0,15398122 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12820213 0,15390556 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12820213 0,15382996 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12820213 0,15375445 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,12820213 0,153679 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,12820213 0,15360363 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12820213 0,15352834 ! telomere organization GO:0032200 46 26 0,000 0,12820213 0,15345311 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12820213 0,15337797 ! alditol metabolic process GO:0019400 44 26 0,000 0,12820213 0,15330289 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12820213 0,15322789 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12820213 0,15315296 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13279209 0,15855869 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13279209 0,15848123 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13279209 0,15840385 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13279209 0,15832654 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13279209 0,15824931 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13279209 0,15817215 ! iron ion transport GO:0006826 65 27 0,000 0,13279209 0,15809507 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13279209 0,15801806 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13279209 0,15794113 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,13279209 0,15786427 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,13279209 0,15778749 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13279209 0,15771078 ! response to starvation GO:0042594 47 27 0,000 0,13279209 0,15763415 ! response to toxin GO:0009636 49 27 0,000 0,13279209 0,15755759 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,13279209 0,15748111 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,13279209 0,1574047 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13279209 0,15732836 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13279209 0,1572521 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13735801 0,16258025 ! vesicle docking GO:0048278 55 28 0,000 0,13735801 0,16250151 ! circadian rhythm GO:0007623 56 28 0,000 0,13735801 0,16242286 ! fat cell differentiation GO:0045444 57 28 0,000 0,13735801 0,16234428 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13735801 0,16226578 ! sperm motility GO:0030317 37 28 0,000 0,13735801 0,16218735 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13735801 0,162109 ! base-excision repair GO:0006284 41 28 0,000 0,13735801 0,16203072 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13735801 0,16195252 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13735801 0,1618744 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13735801 0,16179635 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13735801 0,16171837 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13735801 0,16164048 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13735801 0,16156265 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,13735801 0,1614849 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13735801 0,16140723 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13735801 0,16132963 ! lipid oxidation GO:0034440 48 28 0,000 0,13735801 0,1612521 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13735801 0,16117465 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13735801 0,16109728 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,14190002 0,16634441 ! translational initiation GO:0006413 66 29 0,000 0,14190002 0,16626463 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,14190002 0,16618493 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14190002 0,1661053 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,14190002 0,16602575 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14190002 0,16594627 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14190002 0,16586687 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14190002 0,16578755 ! synaptogenesis GO:0007416 46 29 0,000 0,14190002 0,1657083 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,14190002 0,16562913 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14190002 0,16555003 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14190002 0,16547101 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14190002 0,16539206 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14641825 0,17057691 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14641825 0,1704956 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14641825 0,17041438 ! sensory perception of taste GO:0050909 41 30 0,000 0,14641825 0,17033323 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14641825 0,17025216 ! acute-phase response GO:0006953 50 30 0,000 0,14641825 0,17017116 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14641825 0,17009024 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14641825 0,1700094 ! myofibril assembly GO:0030239 50 30 0,000 0,14641825 0,16992864 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14641825 0,16984795 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14641825 0,16976734 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14641825 0,1696868 ! cell fate determination GO:0001709 64 30 0,000 0,14641825 0,16960634 ! phospholipid transport GO:0015914 65 30 0,000 0,14641825 0,16952596 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14641825 0,16944566 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14641825 0,16936543 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14641825 0,16928527 ! regulation of coagulation GO:0050818 52 30 0,000 0,14641825 0,16920519 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15091281 0,17431678 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15091281 0,1742344 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15091281 0,1741521 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15091281 0,17406987 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15091281 0,17398772 ! ovulation cycle process GO:0022602 55 31 0,000 0,15091281 0,17390565 ! peptide transport GO:0015833 60 31 0,000 0,15091281 0,17382366 ! male gonad development GO:0008584 56 31 0,000 0,15091281 0,17374175 ! iron ion homeostasis GO:0055072 60 31 0,000 0,15091281 0,17365991 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15091281 0,17357815 ! natural killer cell activation GO:0030101 50 31 0,000 0,15091281 0,17349646 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15091281 0,17341486 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15091281 0,17333333 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15091281 0,17325187 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15538383 0,17830093 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15538383 0,17821722 ! collagen metabolic process GO:0032963 49 32 0,000 0,15538383 0,17813359 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15538383 0,17805004 ! spindle organization GO:0007051 50 32 0,000 0,15538383 0,17796657 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15538383 0,17788317 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15538383 0,17779985 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,15538383 0,17771661 ! muscle cell development GO:0055001 52 32 0,000 0,15538383 0,17763345 ! mesoderm formation GO:0001707 73 32 0,000 0,15538383 0,17755037 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15538383 0,17746736 ! ovulation cycle GO:0042698 57 32 0,000 0,15538383 0,17738443 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15538383 0,17730158 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15538383 0,17721881 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15538383 0,17713611 ! gene silencing GO:0016458 71 32 0,000 0,15538383 0,17705349 ! regulation of pH GO:0006885 56 33 0,000 0,15983143 0,18203645 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15983143 0,18195162 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15983143 0,18186687 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15983143 0,18178221 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,15983143 0,18169762 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15983143 0,18161311 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15983143 0,18152867 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,15983143 0,18144432 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15983143 0,18136005 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15983143 0,18127585 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15983143 0,18119173 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16425573 0,18612094 ! post-embryonic development GO:0009791 76 34 0,000 0,16425573 0,18603466 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16425573 0,18594845 ! cholesterol transport GO:0030301 62 34 0,000 0,16425573 0,18586232 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16425573 0,18577628 ! spliceosome assembly GO:0000245 75 34 0,000 0,16425573 0,18569031 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16425573 0,18560442 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16425573 0,18551861 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16425573 0,18543288 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16425573 0,18534723 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16425573 0,18526166 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,16865686 0,19013785 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16865686 0,19005015 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16865686 0,18996253 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,16865686 0,18987499 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16865686 0,18978753 ! membrane docking GO:0022406 69 35 0,000 0,16865686 0,18970015 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16865686 0,18961285 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16865686 0,18952563 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16865686 0,18943849 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16865686 0,18935143 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16865686 0,18926446 ! sterol transport GO:0015918 63 35 0,000 0,16865686 0,18917756 ! placenta development GO:0001890 53 35 0,000 0,16865686 0,18909074 ! vesicle localization GO:0051648 70 35 0,000 0,16865686 0,189004 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,17303494 0,19382135 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,17303494 0,19373252 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17303494 0,19364378 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17303494 0,19355511 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17303494 0,19346653 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17303494 0,19337803 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17303494 0,1932896 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,17303494 0,19320126 ! aerobic respiration GO:0009060 56 36 0,000 0,17303494 0,193113 ! cytokine production GO:0001816 68 36 0,000 0,17303494 0,19302482 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17303494 0,19293673 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17303494 0,19284871 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,17739009 0,1976124 ! sister chromatid segregation GO:0000819 65 37 0,000 0,17739009 0,19752233 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17739009 0,19743234 ! tissue remodeling GO:0048771 78 37 0,000 0,17739009 0,19734243 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17739009 0,19725261 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18172242 0,2019781 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,18172242 0,20188625 ! organic anion transport GO:0015711 82 38 0,000 0,18172242 0,20179448 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18172242 0,2017028 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18172242 0,2016112 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,18172242 0,20151968 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18172242 0,20142825 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18172242 0,2013369 ! spermatid development GO:0007286 69 38 0,000 0,18172242 0,20124563 ! pigment metabolic process GO:0042440 87 38 0,000 0,18172242 0,20115445 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18603205 0,20583166 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,18603205 0,20573848 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,18603205 0,20564539 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18603205 0,20555238 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18603205 0,20545945 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18603205 0,20536661 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18603205 0,20527385 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,19031911 0,20990952 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19031911 0,2098148 ! nucleus organization GO:0006997 73 40 0,000 0,19031911 0,20972016 ! lipid homeostasis GO:0055088 75 40 0,000 0,19031911 0,2096256 ! mismatch repair GO:0006298 58 40 0,000 0,19031911 0,20953113 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,19031911 0,20943675 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,19031911 0,20934245 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19458371 0,213937 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19458371 0,21384076 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19458371 0,21374461 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,19458371 0,21364854 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19458371 0,21355256 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19458371 0,21345667 ! feeding behavior GO:0007631 69 41 0,000 0,19458371 0,21336086 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,19458371 0,21326514 ! mesenchymal cell development GO:0014031 94 41 0,000 0,19458371 0,21316951 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19458371 0,21307396 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,19458371 0,2129785 ! RNA modification GO:0009451 64 41 0,000 0,19458371 0,21288312 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19882597 0,21742696 ! ear morphogenesis GO:0042471 64 42 0,000 0,19882597 0,21732968 ! organic ether metabolic process GO:0018904 59 42 0,000 0,19882597 0,21723249 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19882597 0,21713538 ! T cell differentiation GO:0030217 93 42 0,000 0,19882597 0,21703835 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19882597 0,21694142 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19882597 0,21684457 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19882597 0,21674781 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,203046 0,2212495 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,203046 0,22115086 ! regulation of tube size GO:0035150 76 43 0,000 0,203046 0,22105231 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,203046 0,22095384 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,203046 0,22085546 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,203046 0,22075718 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,203046 0,22065897 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,203046 0,22056086 ! ion transmembrane transport GO:0034220 79 43 0,000 0,203046 0,22046283 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,203046 0,22036489 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,20724392 0,224821 ! hexose transport GO:0008645 68 44 0,000 0,20724392 0,22472121 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,20724392 0,22462151 ! striated muscle contraction GO:0006941 85 44 0,000 0,20724392 0,2245219 ! phagocytosis GO:0006909 105 44 0,000 0,20724392 0,22442238 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20724392 0,22432295 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21141985 0,22874167 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,21141985 0,22864041 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,21141985 0,22853924 ! biopolymer methylation GO:0043414 91 45 0,000 0,21141985 0,22843816 ! B cell differentiation GO:0030183 124 45 0,000 0,21141985 0,22833717 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,21141985 0,22823627 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21141985 0,22813546 ! polyol metabolic process GO:0019751 77 45 0,000 0,21141985 0,22803474 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21557389 0,23241263 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21557389 0,23231011 ! glycolysis GO:0006096 71 46 0,000 0,21557389 0,23220768 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,21557389 0,23210534 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,21557389 0,23200309 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21557389 0,23190093 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,21970617 0,23624216 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,2238168 0,24055629 ! mitochondrial transport GO:0006839 94 48 0,000 0,2238168 0,2404505 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,2238168 0,24034481 ! cellular component disassembly GO:0022411 89 48 0,000 0,2238168 0,24023921 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,2238168 0,2401337 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,2238168 0,24002829 ! male sex differentiation GO:0046661 93 48 0,000 0,2238168 0,23992297 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,2238168 0,23981774 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,2238168 0,2397126 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,2238168 0,23960756 ! methylation GO:0032259 97 48 0,000 0,2238168 0,2395026 ! response to calcium ion GO:0051592 94 49 0,000 0,22790589 0,24377149 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,22790589 0,24366481 ! JNK cascade GO:0007254 106 49 0,000 0,22790589 0,24355822 ! regulation of ion transport GO:0043269 86 50 0,000 0,23197355 0,24779684 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23197355 0,24768854 ! activation of caspase activity GO:0006919 95 50 0,000 0,23197355 0,24758033 ! regulation of ossification GO:0030278 123 50 0,000 0,23197355 0,24747222 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23197355 0,2473642 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,23197355 0,24725627 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23197355 0,24714844 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,23197355 0,2470407 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23197355 0,24693306 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23601989 0,25113092 ! peptide metabolic process GO:0006518 80 51 0,000 0,23601989 0,25102159 ! Notch signaling pathway GO:0007219 111 52 0,000 0,24004503 0,25519148 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,24004503 0,25508048 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24004503 0,25496957 ! excretion GO:0007588 87 52 0,000 0,24004503 0,25485876 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,24004503 0,25474805 ! amino acid activation GO:0043038 98 52 0,000 0,24004503 0,25463743 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24404908 0,25877252 ! inner ear development GO:0048839 89 53 0,000 0,24404908 0,25866026 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24404908 0,25854809 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24404908 0,25843602 ! vesicle organization GO:0016050 127 53 0,000 0,24404908 0,25832404 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,24404908 0,25821217 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,24803214 0,26231278 ! neuromuscular process GO:0050905 107 54 0,000 0,24803214 0,26219927 ! membrane fusion GO:0006944 122 54 0,000 0,24803214 0,26208586 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,24803214 0,26197255 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,24803214 0,26185934 ! regulation of cell shape GO:0008360 142 54 0,000 0,24803214 0,26174623 ! RNA catabolic process GO:0006401 103 55 0,000 0,25199432 0,26581267 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,25199432 0,26569794 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,25199432 0,26558332 ! cell recognition GO:0008037 98 55 0,000 0,25199432 0,26546879 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,25199432 0,26535437 ! glucose catabolic process GO:0006007 88 56 0,000 0,25593574 0,26938864 ! chloride transport GO:0006821 102 57 0,000 0,25985651 0,27339769 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,25985651 0,27328 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,25985651 0,27316241 GO:0010952|positive regulation of peptidase activity, ! regulation of actin filament length GO:0030832 118 58 0,000 0,26375672 0,27714308 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26375672 0,27702393 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26375672 0,27690488 ! gastrulation GO:0007369 122 58 0,000 0,26375672 0,27678594 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,26375672 0,2766671 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,26375672 0,27654835 ! nuclear export GO:0051168 110 59 0,000 0,26763649 0,2804959 ! DNA catabolic process GO:0006308 94 60 0,000 0,27149592 0,28441875 ! regulation of endocytosis GO:0030100 104 60 0,000 0,27149592 0,28429684 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,27149592 0,28417504 ! adult behavior GO:0030534 104 60 0,000 0,27149592 0,28405333 ! positive regulation of secretion GO:0051047 110 61 0,000 0,27533512 0,28794679 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27533512 0,28782358 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27533512 0,28770047 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27533512 0,28757747 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27533512 0,28745458 ! proton transport GO:0015992 117 61 0,000 0,27533512 0,28733178 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,2791542 0,29119288 ! tRNA processing GO:0008033 102 62 0,000 0,2791542 0,29106859 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,2791542 0,29094442 ! mesoderm development GO:0007498 128 63 0,000 0,28295326 0,29477817 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28295326 0,29465252 ! hydrogen transport GO:0006818 121 64 0,000 0,2867324 0,2984607 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,2867324 0,29833358 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,29049173 0,30211635 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,29049173 0,30198779 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,29049173 0,30185934 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,29049173 0,301731 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29049173 0,30160276 ! ear development GO:0043583 114 66 0,000 0,29423135 0,30535565 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29423135 0,30522599 ! activation of MAPK activity GO:0000187 124 67 0,000 0,29795137 0,30895382 ! chromosome segregation GO:0007059 127 67 0,000 0,29795137 0,30882274 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,29795137 0,30869177 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,29795137 0,30856091 ! secondary metabolic process GO:0019748 125 67 0,000 0,29795137 0,30843017 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,30165188 0,31212857 ! hexose catabolic process GO:0019320 113 68 0,000 0,30165188 0,31199642 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30165188 0,31186439 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,30165188 0,31173247 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,30165188 0,31160066 ! adaptive immune response GO:0002250 126 68 0,000 0,30165188 0,31146896 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,30533299 0,31513667 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,30533299 0,31500359 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30533299 0,31487062 ! single fertilization GO:0007338 83 69 0,000 0,30533299 0,31473777 ! cell redox homeostasis GO:0045454 114 70 0,000 0,3089948 0,31837803 ! activation of immune response GO:0002253 120 70 0,000 0,3089948 0,31824381 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,3089948 0,3181097 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,31263742 0,32172418 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31263742 0,32158872 ! carbohydrate transport GO:0008643 114 72 0,000 0,31626093 0,32517906 ! B cell activation GO:0042113 179 72 0,000 0,31626093 0,32504226 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31626093 0,32490557 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31626093 0,324769 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,31626093 0,32463254 ! humoral immune response GO:0006959 115 73 0,000 0,31986544 0,32819457 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,31986544 0,32805679 ! regulation of immune effector process GO:0002697 156 73 0,000 0,31986544 0,32791912 ! acute inflammatory response GO:0002526 118 74 0,000 0,32345105 0,33145592 ! amino acid transport GO:0006865 148 74 0,000 0,32345105 0,33131694 ! regulation of caspase activity GO:0043281 136 74 0,000 0,32345105 0,33117808 ! transition metal ion transport GO:0000041 143 75 0,000 0,32701785 0,33468983 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,32701785 0,33454967 ! rhythmic process GO:0048511 142 75 0,000 0,32701785 0,33440963 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,33056596 0,3378965 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,33056596 0,33775518 ! regulation of blood pressure GO:0008217 134 76 0,000 0,33056596 0,33761398 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,33056596 0,33747289 ! amine catabolic process GO:0009310 136 77 0,000 0,33409545 0,34093366 ! neurotransmitter transport GO:0006836 142 77 0,000 0,33409545 0,34079131 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,33409545 0,34064908 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,33409545 0,34050696 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,33409545 0,34036497 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,33409545 0,34022309 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,33760644 0,34365522 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33760644 0,34351209 ! fertilization GO:0009566 99 78 0,000 0,33760644 0,34336908 ! blood coagulation GO:0007596 151 79 0,000 0,34109901 0,3467769 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,34109901 0,34663265 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,34109901 0,34648852 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,34109901 0,34634451 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34457327 0,34972684 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,34457327 0,3495816 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,35146721 0,35642773 ! exocytosis GO:0006887 153 83 0,000 0,35488709 0,35974654 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35488709 0,35959732 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35488709 0,35944824 ! inorganic anion transport GO:0015698 156 83 0,000 0,35488709 0,35929927 ! response to metal ion GO:0010038 158 84 0,000 0,35828902 0,36259324 ! T cell activation GO:0042110 189 84 0,000 0,35828902 0,3624431 ! digestion GO:0007586 130 84 0,000 0,35828902 0,36229308 ! hemostasis GO:0007599 165 85 0,000 0,36167312 0,36556368 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,36167312 0,3654125 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,36838814 0,37204309 ! mitochondrion organization GO:0007005 159 87 0,000 0,36838814 0,37188935 ! alcohol catabolic process GO:0046164 142 87 0,000 0,36838814 0,37173574 ! nucleosome assembly GO:0006334 126 87 0,000 0,36838814 0,37158226 ! cellular respiration GO:0045333 143 88 0,000 0,37171926 0,37478752 ! sensory perception of smell GO:0007608 117 88 0,000 0,37171926 0,3746329 ! chromatin assembly GO:0031497 128 88 0,000 0,37171926 0,37447841 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,37171926 0,37432405 ! cellular defense response GO:0006968 123 89 0,000 0,3750329 0,37750531 ! regulation of neurological system process GO:0031644 175 89 0,000 0,3750329 0,37734983 ! response to inorganic substance GO:0010035 173 90 0,000 0,37832916 0,38050973 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,37832916 0,38035314 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,38486989 0,3867697 ! amine transport GO:0015837 181 93 0,000 0,38811454 0,38986999 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,39134217 0,39295064 ! female pregnancy GO:0007565 166 94 0,000 0,39134217 0,3927892 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,39134217 0,39262789 ! nucleosome organization GO:0034728 143 95 0,000 0,39455286 0,39568663 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39455286 0,39552426 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,39455286 0,39536203 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39455286 0,39519993 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,39455286 0,39503796 ! mRNA transport GO:0051028 185 100 0,000 0,41035537 0,41069159 ! positive regulation of immune response GO:0050778 175 100 0,000 0,41035537 0,41052341 ! hormone metabolic process GO:0042445 171 100 0,000 0,41035537 0,41035537