pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6261-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of cell-matrix adhesion GO:0001953 36 11 4,000 1,293E-09 3,11E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of protein kinase activity GO:0006469 130 67 7,000 1,596E-09 1,92E-06 ! negative regulation of kinase activity GO:0033673 131 68 7,000 1,801E-09 1,445E-06 ! negative regulation of transferase activity GO:0051348 140 72 7,000 2,868E-09 1,725E-06 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 2,944E-09 1,417E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 8,799E-09 3,528E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 6,000 1,417E-08 4,871E-06 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 2,045E-08 6,15E-06 ! regulation of protein stability GO:0031647 73 37 5,000 2,825E-08 7,553E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 4,074E-08 9,803E-06 ! regulation of cell-matrix adhesion GO:0001952 78 23 4,000 8,971E-08 1,962E-05 GO:0010810|regulation of cell-substrate adhesion, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 1,213E-07 2,432E-05 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,213E-07 2,245E-05 ! regulation of B cell proliferation GO:0030888 20 12 3,000 2,837E-07 4,875E-05 ! negative regulation of protein kinase cascade GO:0010741 68 30 4,000 3,694E-07 5,925E-05 ! protein amino acid autophosphorylation GO:0046777 141 60 5,000 5,537E-07 8,326E-05 ! negative regulation of cell adhesion GO:0007162 81 35 4,000 8,248E-07 1,167E-04 ! endothelial cell migration GO:0043542 28 17 3,000 1,338E-06 1,788E-04 ! inositol metabolic process GO:0006020 28 17 3,000 1,338E-06 1,694E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 1,338E-06 1,609E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 1,338E-06 1,533E-04 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 2,000 2,396E-06 2,62E-04 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 2,692E-06 2,816E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 3,333E-06 3,341E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 4,13E-06 3,974E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 5,598E-06 5,18E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell adhesion GO:0030155 212 89 5,000 5,708E-06 5,086E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 5,812E-06 4,994E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 6,658E-06 5,524E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 6,658E-06 5,34E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 7,366E-06 5,717E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 8,114E-06 6,101E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of cell motion GO:0051271 134 55 4,000 8,158E-06 5,948E-04 ! lipid modification GO:0030258 97 57 4,000 9,741E-06 6,893E-04 ! receptor clustering GO:0043113 18 9 2,000 9,951E-06 6,841E-04 ! dendrite development GO:0016358 59 28 3,000 1,103E-05 7,37E-04 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 3,000 1,103E-05 7,171E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,416E-05 8,968E-04 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 1,416E-05 8,738E-04 ! regulation of B cell activation GO:0050864 50 30 3,000 1,465E-05 8,81E-04 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 3,000 1,907E-05 1,119E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,578E-05 1,477E-03 GO:0042130|negative regulation of T cell proliferation, ! phosphoinositide metabolic process GO:0030384 128 72 4,000 3,066E-05 1,715E-03 ! learning or memory GO:0007611 147 73 4,000 3,278E-05 1,792E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 4,234E-05 2,264E-03 ! mRNA catabolic process GO:0006402 71 39 3,000 4,245E-05 2,22E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 5,187E-05 2,655E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 5,187E-05 2,6E-03 ! polyol metabolic process GO:0019751 66 41 3,000 5,187E-05 2,547E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 5,273E-05 2,537E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 5,71E-05 2,694E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 6,466E-05 2,992E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! signal complex assembly GO:0007172 41 17 2,000 7,823E-05 3,551E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 7,823E-05 3,486E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 8,198E-05 3,586E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 8,198E-05 3,522E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 8,961E-05 3,783E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 9,354E-05 3,88E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 9,7E-05 3,955E-03 ! neuromuscular junction development GO:0007528 34 19 2,000 1,107E-04 4,438E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 1,139E-04 4,493E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,158E-04 4,494E-03 ! regulation of Rho protein signal transduction GO:0035023 213 95 4,000 1,158E-04 4,423E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,297E-04 4,877E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,297E-04 4,802E-03 ! interphase GO:0051325 213 98 4,000 1,341E-04 4,889E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 1,407E-04 5,052E-03 GO:0060538|skeletal muscle organ development, ! RNA catabolic process GO:0006401 93 53 3,000 1,432E-04 5,066E-03 ! response to UV GO:0009411 104 53 3,000 1,432E-04 4,993E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,74E-04 5,979E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,74E-04 5,895E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 1,74E-04 5,813E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,74E-04 5,734E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 1,902E-04 6,184E-03 ! leukocyte adhesion GO:0007159 50 23 2,000 1,993E-04 6,395E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 2,44E-04 7,725E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 2,44E-04 7,624E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,44E-04 7,527E-03 ! microvillus organization GO:0032528 7 5 1,000 2,44E-04 7,431E-03 GO:0030033|microvillus assembly, ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 2,44E-04 7,338E-03 GO:0051489|regulation of filopodium assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,44E-04 7,248E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,44E-04 7,159E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 2,44E-04 7,073E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 2,44E-04 6,989E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,44E-04 6,907E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 2,44E-04 6,826E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 2,44E-04 6,748E-03 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 2,44E-04 6,671E-03 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 2,44E-04 6,596E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! stem cell division GO:0017145 11 5 1,000 2,44E-04 6,523E-03 GO:0048103|somatic stem cell division, ! receptor metabolic process GO:0043112 46 25 2,000 2,57E-04 6,795E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,894E-04 7,57E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 3,244E-04 8,394E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 3,244E-04 8,304E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 3,621E-04 9,17E-03 ! thymic T cell selection GO:0045061 12 6 1,000 3,648E-04 9,143E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 3,648E-04 9,049E-03 ! male sex determination GO:0030238 15 6 1,000 3,648E-04 8,956E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 3,648E-04 8,866E-03 GO:0051653|spindle localization, ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,648E-04 8,777E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 3,648E-04 8,69E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 4,024E-04 9,491E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 4,024E-04 9,399E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 3,000 4,432E-04 0,01025407 ! cell junction assembly GO:0034329 78 30 2,000 4,454E-04 0,01020692 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 4,454E-04 0,01011063 ! mesoderm formation GO:0001707 69 31 2,000 4,914E-04 0,01104894 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 4,914E-04 0,01094663 GO:0043433|negative regulation of transcription factor activity, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,091E-04 0,01123664 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,091E-04 0,01113449 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 5,091E-04 0,01103417 ! positive regulation of isotype switching GO:0045830 15 7 1,000 5,091E-04 0,01093566 GO:0045911|positive regulation of DNA recombination, ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 5,091E-04 0,01083888 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 5,091E-04 0,0107438 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of respiratory burst GO:0060263 11 7 1,000 5,091E-04 0,01065038 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 5,091E-04 0,01055856 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 5,091E-04 0,01046832 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 5,091E-04 0,0103796 ! regulation of transcription factor activity GO:0051090 126 74 3,000 5,189E-04 0,01049056 GO:0090046|regulation of transcription regulator activity, ! regulation of protein import into nucleus GO:0042306 63 32 2,000 5,402E-04 0,01083158 ! formation of primary germ layer GO:0001704 72 33 2,000 5,921E-04 0,01177329 ! negative regulation of protein transport GO:0051224 69 33 2,000 5,921E-04 0,01167679 ! mesoderm morphogenesis GO:0048332 76 34 2,000 6,47E-04 0,01265648 ! regulation of peptidase activity GO:0052547 134 79 3,000 6,646E-04 0,01289588 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,765E-04 0,01302174 ! ER overload response GO:0006983 12 8 1,000 6,765E-04 0,01291839 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,765E-04 0,01281667 ! synaptic transmission, glutamatergic GO:0035249 17 8 1,000 6,765E-04 0,01271654 ! dendrite morphogenesis GO:0048813 13 8 1,000 6,765E-04 0,01261797 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 6,765E-04 0,01252091 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 6,765E-04 0,01242533 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 7,051E-04 0,01285229 ! regulation of microtubule-based process GO:0032886 78 35 2,000 7,051E-04 0,01275565 ! cell junction organization GO:0034330 86 36 2,000 7,664E-04 0,01376121 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 7,664E-04 0,01365927 ! negative regulation of cell activation GO:0050866 65 36 2,000 7,664E-04 0,01355884 ! negative regulation of DNA binding GO:0043392 68 37 2,000 8,31E-04 0,01459427 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 8,31E-04 0,01448851 ! regulation of developmental growth GO:0048638 15 9 1,000 8,67E-04 0,01500676 ! axon extension GO:0048675 15 9 1,000 8,67E-04 0,01489957 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 8,67E-04 0,0147939 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 8,67E-04 0,01468971 ! regulation of glycolysis GO:0006110 21 9 1,000 8,67E-04 0,01458699 ! microtubule bundle formation GO:0001578 21 9 1,000 8,67E-04 0,01448569 ! middle ear morphogenesis GO:0042474 14 9 1,000 8,67E-04 0,01438579 ! T cell selection GO:0045058 23 9 1,000 8,67E-04 0,01428725 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 8,67E-04 0,01419006 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 1,000 8,67E-04 0,01409418 ! motor axon guidance GO:0008045 16 9 1,000 8,67E-04 0,01399959 ! protein heterooligomerization GO:0051291 16 9 1,000 8,67E-04 0,01390626 ! gas homeostasis GO:0033483 16 9 1,000 8,67E-04 0,01381417 ! postreplication repair GO:0006301 22 9 1,000 8,67E-04 0,01372328 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 8,67E-04 0,01363359 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 8,99E-04 0,01404484 ! carbohydrate homeostasis GO:0033500 53 38 2,000 8,99E-04 0,01395423 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 8,99E-04 0,01386478 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of protein transport GO:0051223 154 87 3,000 9,548E-04 0,01463222 GO:0070201|regulation of establishment of protein localization, ! mammary gland development GO:0030879 86 39 2,000 9,703E-04 0,01477618 ! Rho protein signal transduction GO:0007266 74 39 2,000 9,703E-04 0,01468325 ! regulation of DNA binding GO:0051101 155 88 3,000 9,964E-04 0,01498391 ! negative regulation of binding GO:0051100 72 40 2,000 1,045E-03 0,01561966 ! mesenchymal cell development GO:0014031 87 40 2,000 1,045E-03 0,01552324 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,08E-03 0,0159442 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,08E-03 0,01584698 ! central nervous system neuron axonogenesis GO:0021955 22 10 1,000 1,08E-03 0,01575094 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,08E-03 0,01565605 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,08E-03 0,0155623 ! midbrain development GO:0030901 13 10 1,000 1,08E-03 0,01546967 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,08E-03 0,01537813 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,08E-03 0,01528767 ! localization within membrane GO:0051668 20 10 1,000 1,08E-03 0,01519827 ! T cell differentiation GO:0030217 81 41 2,000 1,124E-03 0,01571772 ! neuron migration GO:0001764 79 42 2,000 1,206E-03 0,01676784 ! regulation of T cell activation GO:0050863 158 94 3,000 1,273E-03 0,01760816 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,291E-03 0,01775475 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,316E-03 0,017989 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,316E-03 0,01788737 ! T cell proliferation GO:0042098 26 11 1,000 1,316E-03 0,01778688 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,316E-03 0,01768751 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,316E-03 0,01758924 ! regulation of isotype switching GO:0045191 22 11 1,000 1,316E-03 0,01749207 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,316E-03 0,01739596 ! regulation of embryonic development GO:0045995 27 11 1,000 1,316E-03 0,0173009 ! regulation of protein localization GO:0032880 176 97 3,000 1,43E-03 0,0187026 ! response to insulin stimulus GO:0032868 95 46 2,000 1,571E-03 0,02043466 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,571E-03 0,02032479 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,574E-03 0,02025065 ! virus-host interaction GO:0019048 29 12 1,000 1,574E-03 0,02014294 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,574E-03 0,02003636 ! regulation of cell projection assembly GO:0060491 30 12 1,000 1,574E-03 0,01993091 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,574E-03 0,01982656 ! focal adhesion formation GO:0048041 35 12 1,000 1,574E-03 0,01972329 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 1,000 1,574E-03 0,0196211 ! histone acetylation GO:0016573 26 12 1,000 1,574E-03 0,01951996 ! gland morphogenesis GO:0022612 29 12 1,000 1,574E-03 0,01941986 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,574E-03 0,01932078 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 1,000 1,574E-03 0,0192227 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,777E-03 0,02159698 ! activation of caspase activity GO:0006919 84 48 2,000 1,777E-03 0,02148845 ! lipid localization GO:0010876 28 13 1,000 1,854E-03 0,02230394 GO:0019915|lipid storage, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,854E-03 0,02219298 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,854E-03 0,02208311 ! positive regulation of homeostatic process GO:0032846 21 13 1,000 1,854E-03 0,02197433 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 1,854E-03 0,02186661 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,854E-03 0,02175994 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,854E-03 0,02165431 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,117E-03 0,02460354 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,156E-03 0,02493882 ! regulation of S phase GO:0033261 23 14 1,000 2,156E-03 0,0248195 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,156E-03 0,02470131 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,156E-03 0,02458424 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 2,156E-03 0,02446828 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,156E-03 0,0243534 ! synapse organization GO:0050808 85 52 2,000 2,238E-03 0,02516435 ! heterophilic cell adhesion GO:0007157 39 15 1,000 2,48E-03 0,0277479 ! regulation of vasodilation GO:0042312 26 15 1,000 2,48E-03 0,02761944 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 2,48E-03 0,02749216 ! positive regulation of calcium ion transport GO:0051928 19 15 1,000 2,48E-03 0,02736605 ! activation of phospholipase C activity GO:0007202 103 54 2,000 2,494E-03 0,02739898 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 2,628E-03 0,02874356 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,628E-03 0,0286135 GO:0010952|positive regulation of peptidase activity, ! gastrulation GO:0007369 112 55 2,000 2,628E-03 0,02848461 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,767E-03 0,02985357 ! positive regulation of organelle organization GO:0010638 100 56 2,000 2,767E-03 0,02972029 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,825E-03 0,03020369 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 2,825E-03 0,03007005 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 2,825E-03 0,02993758 ! positive regulation of ion transport GO:0043270 21 16 1,000 2,825E-03 0,02980627 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,825E-03 0,02967611 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,825E-03 0,02954709 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of immune response GO:0050777 35 16 1,000 2,825E-03 0,02941918 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,825E-03 0,02929237 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 2,825E-03 0,02916665 ! defense response to virus GO:0051607 37 16 1,000 2,825E-03 0,02904201 ! muscle fiber development GO:0048747 112 57 2,000 2,91E-03 0,0297948 ! positive regulation of cell migration GO:0030335 126 57 2,000 2,91E-03 0,02966855 ! regulation of phospholipase activity GO:0010517 106 57 2,000 2,91E-03 0,02954336 ! positive regulation of lipase activity GO:0060193 108 58 2,000 3,058E-03 0,03091171 ! positive regulation of cell killing GO:0031343 32 17 1,000 3,191E-03 0,03212069 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 3,191E-03 0,03198685 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,191E-03 0,03185412 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,191E-03 0,0317225 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,191E-03 0,03159195 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 3,191E-03 0,03146248 GO:0002712|regulation of B cell mediated immunity, ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 3,191E-03 0,03133406 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,191E-03 0,03120668 ! mesoderm development GO:0007498 119 61 2,000 3,528E-03 0,03436583 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 3,528E-03 0,03422726 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,578E-03 0,03457156 ! memory GO:0007613 31 18 1,000 3,578E-03 0,03443327 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,578E-03 0,03429609 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 3,578E-03 0,03415999 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,578E-03 0,03402497 ! regulation of homeostatic process GO:0032844 134 62 2,000 3,694E-03 0,03499111 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 3,865E-03 0,03646438 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 3,986E-03 0,03745991 ! lipid phosphorylation GO:0046834 35 19 1,000 3,986E-03 0,03731415 ! forelimb morphogenesis GO:0035136 32 19 1,000 3,986E-03 0,03716952 ! actin filament bundle formation GO:0051017 42 19 1,000 3,986E-03 0,03702601 ! protein export from nucleus GO:0006611 36 19 1,000 3,986E-03 0,0368836 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 3,986E-03 0,03674228 ! positive regulation of cell motion GO:0051272 146 64 2,000 4,04E-03 0,03710107 ! actin filament organization GO:0007015 148 66 2,000 4,405E-03 0,04030097 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 4,414E-03 0,04022948 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,414E-03 0,04007767 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 4,414E-03 0,039927 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 4,414E-03 0,03977746 ! cellular response to starvation GO:0009267 33 20 1,000 4,414E-03 0,03962904 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 4,414E-03 0,03948172 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,414E-03 0,03933549 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 4,414E-03 0,03919034 ! negative regulation of cell growth GO:0030308 132 67 2,000 4,595E-03 0,04064686 ! activation of MAPK activity GO:0000187 115 67 2,000 4,595E-03 0,04049797 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 4,595E-03 0,04035016 ! negative regulation of ligase activity GO:0051352 112 68 2,000 4,79E-03 0,04190722 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 4,79E-03 0,04175539 ! regulation of lipase activity GO:0060191 130 68 2,000 4,79E-03 0,04160464 ! regulation of cell killing GO:0031341 42 21 1,000 4,863E-03 0,04208758 ! hindlimb morphogenesis GO:0035137 43 21 1,000 4,863E-03 0,04193673 ! inactivation of MAPK activity GO:0000188 39 21 1,000 4,863E-03 0,04178696 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 4,863E-03 0,04163825 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 4,863E-03 0,0414906 ! regulation of vasoconstriction GO:0019229 39 21 1,000 4,863E-03 0,04134399 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,863E-03 0,04119841 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 4,863E-03 0,04105385 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 4,863E-03 0,04091031 ! negative regulation of cell size GO:0045792 134 69 2,000 4,99E-03 0,0418288 ! glutamate signaling pathway GO:0007215 41 22 1,000 5,332E-03 0,0445435 ! central nervous system neuron development GO:0021954 46 22 1,000 5,332E-03 0,04438937 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 5,332E-03 0,0442363 ! apoptotic nuclear changes GO:0030262 32 22 1,000 5,332E-03 0,04408429 ! ureteric bud development GO:0001657 43 22 1,000 5,332E-03 0,04393331 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 5,332E-03 0,04378337 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 5,332E-03 0,04363445 ! protein stabilization GO:0050821 39 22 1,000 5,332E-03 0,04348653 ! regulation of caspase activity GO:0043281 122 72 2,000 5,618E-03 0,04566836 ! positive regulation of DNA replication GO:0045740 43 23 1,000 5,821E-03 0,04715359 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,821E-03 0,04699536 ! regulation of DNA recombination GO:0000018 48 23 1,000 5,821E-03 0,04683818 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 5,821E-03 0,04668205 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 47 23 1,000 5,821E-03 0,04652696 ! nerve-nerve synaptic transmission GO:0007270 49 23 1,000 5,821E-03 0,0463729 ! negative regulation of catabolic process GO:0009895 50 23 1,000 5,821E-03 0,04621986 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,063E-03 0,04798397 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 6,293E-03 0,04963996 ! lymphocyte differentiation GO:0030098 167 75 2,000 6,293E-03 0,04947774 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,329E-03 0,04960299 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 6,329E-03 0,04944194 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 6,329E-03 0,04928193 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 6,329E-03 0,04912296 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 6,329E-03 0,04896501 ! lymphocyte proliferation GO:0046651 48 24 1,000 6,329E-03 0,04880807 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 6,329E-03 0,04865213 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 39 24 1,000 6,329E-03 0,04849719 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 6,329E-03 0,04834323 ! protein tetramerization GO:0051262 52 24 1,000 6,329E-03 0,04819024 ! regulation of catabolic process GO:0009894 161 76 2,000 6,528E-03 0,04954455 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 6,768E-03 0,05120596 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 6,857E-03 0,05171955 ! myelination GO:0042552 45 25 1,000 6,857E-03 0,05155792 ! vasculogenesis GO:0001570 46 25 1,000 6,857E-03 0,05139731 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 6,857E-03 0,05123769 ! response to starvation GO:0042594 42 25 1,000 6,857E-03 0,05107906 ! osteoblast differentiation GO:0001649 60 25 1,000 6,857E-03 0,0509214 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,857E-03 0,05076472 ! interaction with host GO:0051701 62 25 1,000 6,857E-03 0,050609 ! somitogenesis GO:0001756 43 25 1,000 6,857E-03 0,05045424 ! immunoglobulin production GO:0002377 55 25 1,000 6,857E-03 0,05030041 GO:0002440|production of molecular mediator of immune response, ! regulation of blood coagulation GO:0030193 40 25 1,000 6,857E-03 0,05014752 ! cellular response to nutrient levels GO:0031669 41 25 1,000 6,857E-03 0,04999556 ! neural tube closure GO:0001843 49 25 1,000 6,857E-03 0,04984452 GO:0060606|tube closure, ! negative regulation of organelle organization GO:0010639 161 78 2,000 7,013E-03 0,05082493 ! protein oligomerization GO:0051259 139 78 2,000 7,013E-03 0,0506723 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 7,264E-03 0,05232583 ! regulation of synaptic transmission GO:0050804 134 79 2,000 7,264E-03 0,05216964 ! embryonic pattern specification GO:0009880 44 26 1,000 7,405E-03 0,05302196 ! tube lumen formation GO:0035148 50 26 1,000 7,405E-03 0,05286462 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 7,405E-03 0,05270822 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 7,405E-03 0,05255274 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 7,405E-03 0,05239817 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 7,405E-03 0,05224451 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 7,405E-03 0,05209175 ! positive regulation of nuclear division GO:0051785 40 26 1,000 7,405E-03 0,05193988 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 7,405E-03 0,05178889 ! leukocyte proliferation GO:0070661 52 26 1,000 7,405E-03 0,05163878 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 7,405E-03 0,05148953 ! T cell activation GO:0042110 168 81 2,000 7,781E-03 0,05395013 ! response to hypoxia GO:0001666 171 81 2,000 7,781E-03 0,0537951 ! regulation of neuron differentiation GO:0045664 167 81 2,000 7,781E-03 0,05364096 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 7,971E-03 0,05479474 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 7,971E-03 0,05463863 ! protein amino acid acylation GO:0043543 55 27 1,000 7,971E-03 0,05448341 ! primary neural tube formation GO:0014020 51 27 1,000 7,971E-03 0,05432906 ! regulation of chromosome organization GO:0033044 42 27 1,000 7,971E-03 0,05417559 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 8,047E-03 0,05454008 ! response to oxygen levels GO:0070482 176 83 2,000 8,319E-03 0,05622351 ! negative regulation of protein modification process GO:0031400 60 28 1,000 8,556E-03 0,05766497 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 8,556E-03 0,0575039 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 8,556E-03 0,05734372 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 8,556E-03 0,05718443 ! negative regulation of transport GO:0051051 153 84 2,000 8,596E-03 0,05729163 ! negative regulation of growth GO:0045926 155 84 2,000 8,596E-03 0,05713337 ! regulation of ligase activity GO:0051340 142 84 2,000 8,596E-03 0,05697598 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 8,596E-03 0,05681945 ! positive regulation of cell activation GO:0050867 145 85 2,000 8,879E-03 0,05852577 GO:0002696|positive regulation of leukocyte activation, ! immune response-activating signal transduction GO:0002757 47 29 1,000 9,16E-03 0,0602175 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 9,16E-03 0,06005342 ! regulation of coagulation GO:0050818 46 29 1,000 9,16E-03 0,05989023 ! tube morphogenesis GO:0035239 176 86 2,000 9,166E-03 0,0597683 ! gland development GO:0048732 206 88 2,000 9,758E-03 0,06345622 ! regulation of neurological system process GO:0031644 148 88 2,000 9,758E-03 0,06328518 ! zinc ion transport GO:0006829 45 30 1,000 9,783E-03 0,06327234 ! ensheathment of neurons GO:0007272 57 30 1,000 9,783E-03 0,0631027 GO:0008366|axon ensheathment, ! ossification GO:0001503 188 90 2,000 0,01037222 0,06672608 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01042354 0,06687743 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01042354 0,06669957 GO:0055092|sterol homeostasis, ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01042354 0,06652265 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01042354 0,06634666 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01042354 0,0661716 ! bone development GO:0060348 189 91 2,000 0,01068733 0,06766766 ! cholesterol transport GO:0030301 56 32 1,000 0,01108243 0,06998509 ! spindle organization GO:0007051 46 32 1,000 0,01108243 0,06980189 ! metanephros development GO:0001656 74 32 1,000 0,01108243 0,06961964 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01108243 0,06943834 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01108243 0,06925798 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01108243 0,06907855 ! hindbrain development GO:0030902 61 32 1,000 0,01108243 0,06890005 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01108243 0,06872248 ! regulation of calcium ion transport GO:0051924 53 32 1,000 0,01108243 0,06854581 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01108243 0,06837005 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01133408 0,0697437 ! cell fate specification GO:0001708 52 33 1,000 0,01175922 0,07217524 ! sterol transport GO:0015918 57 33 1,000 0,01175922 0,07199158 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01234575 0,07539057 ! mRNA transport GO:0051028 169 96 2,000 0,01234575 0,07519971 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01245374 0,07566588 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01245374 0,07547529 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01269412 0,07673883 ! regulation of muscle development GO:0048634 70 35 1,000 0,01316577 0,07939061 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01316577 0,07919213 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01316577 0,07899464 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01316577 0,07879814 ! neural tube formation GO:0001841 67 35 1,000 0,01316577 0,07860261 ! cell cycle arrest GO:0007050 213 100 2,000 0,01377282 0,08202328 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01389515 0,08254747 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01389515 0,08234415 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01389515 0,08214183 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01389515 0,0819405 ! meiosis I GO:0007127 65 37 1,000 0,01464167 0,08613168 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01464167 0,0859216 ! tissue remodeling GO:0048771 76 37 1,000 0,01464167 0,08571255 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,01464167 0,08550451 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01464167 0,08529748 ! regulation of metal ion transport GO:0010959 63 38 1,000 0,01540515 0,0895285 ! nucleus organization GO:0006997 67 38 1,000 0,01540515 0,08931277 ! lipid homeostasis GO:0055088 67 38 1,000 0,01540515 0,08909807 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01540515 0,08888441 ! glucan metabolic process GO:0044042 62 38 1,000 0,01540515 0,08867177 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,01618541 0,09294058 ! ear morphogenesis GO:0042471 60 39 1,000 0,01618541 0,0927193 ! organic ether metabolic process GO:0018904 55 39 1,000 0,01618541 0,09249906 ! segmentation GO:0035282 67 39 1,000 0,01618541 0,09227987 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01618541 0,09206171 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01618541 0,09184459 ! maintenance of protein location GO:0045185 91 40 1,000 0,01698227 0,09613961 ! cytokinesis GO:0000910 72 40 1,000 0,01698227 0,09591393 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,01779553 0,10027177 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01862502 0,10470048 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01862502 0,10445642 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,01862502 0,1042135 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01947057 0,10869184 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,01947057 0,10844024 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01947057 0,1081898 ! neural tube development GO:0021915 77 43 1,000 0,01947057 0,10794051 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02033198 0,11245689 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02033198 0,11219896 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02120909 0,11677134 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02120909 0,11650474 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,02120909 0,11623935 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02210172 0,12085623 ! endosome transport GO:0016197 108 47 1,000 0,0230097 0,12553589 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0230097 0,12525187 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,0230097 0,12496914 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,0230097 0,12468768 ! protein homooligomerization GO:0051260 76 47 1,000 0,0230097 0,12440748 ! cellular component disassembly GO:0022411 86 48 1,000 0,02393284 0,12910857 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02393284 0,12881973 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02393284 0,12853219 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02465767 0,13212997 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02465767 0,13183635 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02465767 0,13154403 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02465767 0,131253 ! neuron fate determination GO:0048664 7 5 0,000 0,02465767 0,13096326 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02465767 0,13067479 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02465767 0,1303876 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02465767 0,13010166 ! polyol transport GO:0015791 12 5 0,000 0,02465767 0,12981697 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02465767 0,12953353 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02465767 0,12925132 ! response to superoxide GO:0000303 10 5 0,000 0,02465767 0,12897034 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02465767 0,12869058 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02465767 0,12841203 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02465767 0,12813468 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02465767 0,12785853 ! female meiosis GO:0007143 7 5 0,000 0,02465767 0,12758356 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02465767 0,12730978 ! cobalt ion transport GO:0006824 11 5 0,000 0,02465767 0,12703717 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02465767 0,12676572 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02465767 0,12649543 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02465767 0,12622629 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02465767 0,12595829 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02465767 0,12569143 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02465767 0,1254257 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02465767 0,12516109 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02465767 0,12489759 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02465767 0,1246352 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02465767 0,12437391 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02465767 0,12411372 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02465767 0,12385461 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02465767 0,12359658 ! negative chemotaxis GO:0050919 14 5 0,000 0,02465767 0,12333962 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02465767 0,12308373 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02465767 0,1228289 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02465767 0,12257512 ! behavioral response to pain GO:0048266 9 5 0,000 0,02465767 0,12232238 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02465767 0,12207069 ! Notch receptor processing GO:0007220 8 5 0,000 0,02465767 0,12182003 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02465767 0,1215704 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02465767 0,12132179 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02465767 0,1210742 ! copulation GO:0007620 9 5 0,000 0,02465767 0,12082761 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02465767 0,12058203 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02465767 0,12033744 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02465767 0,12009384 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02465767 0,11985123 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02465767 0,11960959 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02465767 0,11936893 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02465767 0,11912923 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02465767 0,11889049 ! grooming behavior GO:0007625 6 5 0,000 0,02465767 0,11865271 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02465767 0,11841588 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02465767 0,11817999 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02465767 0,11794504 ! response to protozoan GO:0001562 10 5 0,000 0,02465767 0,11771102 ! lymph vessel development GO:0001945 10 5 0,000 0,02465767 0,11747793 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02465767 0,11724576 ! endochondral ossification GO:0001958 16 5 0,000 0,02465767 0,11701451 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02465767 0,11678417 ! parathyroid gland development GO:0060017 13 5 0,000 0,02465767 0,11655473 ! anagen GO:0042640 6 5 0,000 0,02465767 0,11632619 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02465767 0,11609855 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02465767 0,11587179 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02465767 0,11564592 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02465767 0,11542093 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02465767 0,11519681 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02465767 0,11497356 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02465767 0,11475117 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02465767 0,11452965 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02465767 0,11430897 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02465767 0,11408915 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02465767 0,11387017 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02465767 0,11365202 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02465767 0,11343472 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02465767 0,11321824 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02465767 0,11300258 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02465767 0,11278775 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02465767 0,11257373 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02465767 0,11236052 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02465767 0,11214812 ! histidine catabolic process GO:0006548 6 5 0,000 0,02465767 0,11193652 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02465767 0,11172572 ! valine metabolic process GO:0006573 10 5 0,000 0,02465767 0,11151571 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02465767 0,11130649 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02465767 0,11109805 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02465767 0,11089039 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02465767 0,1106835 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02465767 0,11047739 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02465767 0,11027204 ! polyol catabolic process GO:0046174 7 5 0,000 0,02465767 0,11006745 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02465767 0,10986362 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02465767 0,10966055 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02465767 0,10945822 ! muscle cell migration GO:0014812 8 5 0,000 0,02465767 0,10925664 ! mitochondrial fission GO:0000266 8 5 0,000 0,02465767 0,1090558 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02465767 0,1088557 ! mRNA transcription GO:0009299 9 5 0,000 0,02465767 0,10865633 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02465767 0,10845769 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02465767 0,10825977 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02465767 0,10806258 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02465767 0,1078661 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02465767 0,10767034 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02465767 0,10747528 ! response to food GO:0032094 6 5 0,000 0,02465767 0,10728093 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02465767 0,10708729 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02465767 0,10689434 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02465767 0,10670208 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02465767 0,10651051 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02465767 0,10631964 ! forebrain neuron development GO:0021884 13 5 0,000 0,02465767 0,10612944 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02465767 0,10593992 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02465767 0,10575108 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02465767 0,10556291 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02465767 0,10537541 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02465767 0,10518858 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02465767 0,1050024 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02465767 0,10481688 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02465767 0,10463202 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02465767 0,10444781 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02465767 0,10426425 ! basic amino acid transport GO:0015802 11 5 0,000 0,02465767 0,10408133 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02465767 0,10389905 ! depyrimidination GO:0045008 10 5 0,000 0,02465767 0,10371741 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02465767 0,1035364 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02465767 0,10335602 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02465767 0,10317627 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02465767 0,10299715 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02465767 0,10281864 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02465767 0,10264076 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02465767 0,10246348 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02465767 0,10228682 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02465767 0,10211077 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02465767 0,10193532 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02465767 0,10176047 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02465767 0,10158623 ! response to arsenic GO:0046685 10 5 0,000 0,02465767 0,10141258 ! mast cell degranulation GO:0043303 7 5 0,000 0,02465767 0,10123952 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02465767 0,10106705 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02465767 0,10089516 ! response to cadmium ion GO:0046686 7 5 0,000 0,02465767 0,10072387 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02465767 0,10055315 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02465767 0,10038301 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02465767 0,10021344 ! decidualization GO:0046697 11 5 0,000 0,02465767 0,10004445 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02465767 0,09987602 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02465767 0,09970816 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02465767 0,09954087 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02465767 0,09937413 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02465767 0,09920795 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02465767 0,09904233 ! neural tube patterning GO:0021532 7 5 0,000 0,02465767 0,09887726 ! embryonic cleavage GO:0040016 6 5 0,000 0,02465767 0,09871274 ! peroxisome fission GO:0016559 5 5 0,000 0,02465767 0,09854876 ! histone demethylation GO:0016577 10 5 0,000 0,02465767 0,09838533 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02465767 0,09822244 ! mitotic recombination GO:0006312 9 5 0,000 0,02465767 0,09806009 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02465767 0,09789828 ! metaphase plate congression GO:0051310 7 5 0,000 0,02465767 0,097737 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02465767 0,09757624 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02465767 0,09741602 ! enteric nervous system development GO:0048484 8 5 0,000 0,02465767 0,09725632 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02465767 0,09709715 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02465767 0,09693849 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02465767 0,09678035 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02465767 0,09662273 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02465767 0,09646562 ! plasminogen activation GO:0031639 5 5 0,000 0,02465767 0,09630902 ! B cell homeostasis GO:0001782 13 5 0,000 0,02465767 0,09615293 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02465767 0,09599734 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02465767 0,09584226 ! metaphase GO:0051323 8 5 0,000 0,02465767 0,09568767 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02465767 0,09553359 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02465767 0,09537999 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02465767 0,0952269 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02465767 0,09507429 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02465767 0,09492217 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02465767 0,09477054 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02465767 0,09461939 ! response to redox state GO:0051775 5 5 0,000 0,02465767 0,09446872 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02465767 0,09431853 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02465767 0,09416882 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02465767 0,09401958 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02465767 0,09387082 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02465767 0,09372252 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02465767 0,09357469 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02465767 0,09342733 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02465767 0,09328043 ! striatum development GO:0021756 9 5 0,000 0,02465767 0,093134 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02465767 0,09298802 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02465767 0,0928425 ! glial cell migration GO:0008347 11 5 0,000 0,02465767 0,09269743 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02465767 0,09255282 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02465767 0,09240866 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02465767 0,09226494 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02465767 0,09212167 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02465767 0,09197885 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02465767 0,09183647 ! neuroprotection GO:0043526 6 5 0,000 0,02465767 0,09169452 ! neural plate development GO:0001840 8 5 0,000 0,02465767 0,09155302 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02465767 0,09141195 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02465767 0,09127132 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02465767 0,09113112 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02465767 0,09099134 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02465767 0,090852 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02465767 0,09071308 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02465767 0,09057459 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02465767 0,09043652 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02465767 0,09029887 ! spindle assembly GO:0051225 6 5 0,000 0,02465767 0,09016164 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02465767 0,09002482 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02465767 0,08988842 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02465767 0,08975243 ! drug metabolic process GO:0017144 6 5 0,000 0,02465767 0,08961685 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02465767 0,08948168 ! organ regeneration GO:0031100 7 5 0,000 0,02465767 0,08934692 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02465767 0,08921257 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02465767 0,08907861 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02465767 0,08894506 ! regulation of action potential GO:0001508 95 49 1,000 0,02487099 0,08958025 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02487099 0,08944635 ! regulation of ion transport GO:0043269 77 49 1,000 0,02487099 0,08931284 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,02582397 0,09259683 ! regulation of ossification GO:0030278 117 50 1,000 0,02582397 0,09245904 ! inner ear development GO:0048839 79 50 1,000 0,02582397 0,09232165 ! histone modification GO:0016570 91 50 1,000 0,02582397 0,09218468 ! positive regulation of binding GO:0051099 78 51 1,000 0,02679161 0,09549721 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,02679161 0,09535594 ! vesicle organization GO:0016050 107 51 1,000 0,02679161 0,09521509 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02777375 0,09855993 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,02777375 0,09841478 ! positive regulation of growth GO:0045927 90 52 1,000 0,02777375 0,09827005 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02777375 0,09812575 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,02777375 0,09798187 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02877021 0,10134865 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02951624 0,10382468 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02951624 0,10367311 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02951624 0,10352199 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02951624 0,1033713 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02951624 0,10322105 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02951624 0,10307124 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02951624 0,10292186 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02951624 0,10277291 ! sleep GO:0030431 13 6 0,000 0,02951624 0,1026244 ! response to oxygen radical GO:0000305 11 6 0,000 0,02951624 0,10247631 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02951624 0,10232865 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02951624 0,10218141 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02951624 0,1020346 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02951624 0,10188821 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02951624 0,10174224 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02951624 0,10159669 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02951624 0,10145155 ! forebrain regionalization GO:0021871 8 6 0,000 0,02951624 0,10130682 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02951624 0,10116251 ! male meiosis GO:0007140 7 6 0,000 0,02951624 0,10101861 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02951624 0,10087512 ! response to zinc ion GO:0010043 9 6 0,000 0,02951624 0,10073203 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02951624 0,10058935 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02951624 0,10044708 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02951624 0,1003052 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02951624 0,10016373 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02951624 0,10002265 ! malate metabolic process GO:0006108 11 6 0,000 0,02951624 0,09988197 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02951624 0,09974169 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02951624 0,0996018 ! protein refolding GO:0042026 15 6 0,000 0,02951624 0,0994623 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02951624 0,09932319 ! opsonization GO:0008228 8 6 0,000 0,02951624 0,09918447 ! mating behavior GO:0007617 7 6 0,000 0,02951624 0,09904614 ! neuron remodeling GO:0016322 15 6 0,000 0,02951624 0,09890819 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02951624 0,09877063 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02951624 0,09863345 ! equilibrioception GO:0050957 14 6 0,000 0,02951624 0,09849665 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02951624 0,09836023 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02951624 0,09822418 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02951624 0,09808851 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02951624 0,09795322 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02951624 0,0978183 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02951624 0,09768375 ! toxin metabolic process GO:0009404 11 6 0,000 0,02951624 0,09754956 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02951624 0,09741575 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02951624 0,09728231 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02951624 0,09714922 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02951624 0,09701651 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02951624 0,09688415 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02951624 0,09675216 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02951624 0,09662052 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02951624 0,09648924 ! protein lipoylation GO:0009249 10 6 0,000 0,02951624 0,09635832 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02951624 0,09622775 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02951624 0,09609754 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02951624 0,09596768 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02951624 0,09583817 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,02951624 0,09570901 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02951624 0,09558019 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02951624 0,09545172 ! hyperosmotic response GO:0006972 9 6 0,000 0,02951624 0,0953236 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02951624 0,09519582 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02951624 0,09506838 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02951624 0,09494129 ! urea metabolic process GO:0019627 7 6 0,000 0,02951624 0,09481453 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02951624 0,09468811 ! neutrophil activation GO:0042119 8 6 0,000 0,02951624 0,09456203 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02951624 0,09443628 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02951624 0,09431087 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02951624 0,09418579 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02951624 0,09406104 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02951624 0,09393662 ! neuron apoptosis GO:0051402 9 6 0,000 0,02951624 0,09381253 ! nucleoside salvage GO:0043174 9 6 0,000 0,02951624 0,09368876 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02951624 0,09356533 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02951624 0,09344221 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02951624 0,09331943 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02951624 0,09319696 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02951624 0,09307481 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02951624 0,09295299 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02951624 0,09283148 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02951624 0,09271029 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02951624 0,09258942 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02951624 0,09246886 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02951624 0,09234861 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02951624 0,09222868 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02951624 0,09210906 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02951624 0,09198974 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02951624 0,09187074 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02951624 0,09175205 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02951624 0,09163366 ! neural nucleus development GO:0048857 14 6 0,000 0,02951624 0,09151557 ! response to UV-C GO:0010225 11 6 0,000 0,02951624 0,09139779 ! astrocyte development GO:0014002 15 6 0,000 0,02951624 0,09128031 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02951624 0,09116314 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02951624 0,09104626 ! interaction with symbiont GO:0051702 13 6 0,000 0,02951624 0,09092968 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02951624 0,09081341 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02951624 0,09069742 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02951624 0,09058174 ! response to copper ion GO:0046688 10 6 0,000 0,02951624 0,09046635 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02951624 0,09035125 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02951624 0,09023645 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02951624 0,09012193 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02951624 0,09000771 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02951624 0,08989378 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02951624 0,08978013 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02951624 0,08966677 ! hair follicle maturation GO:0048820 7 6 0,000 0,02951624 0,0895537 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02951624 0,08944091 ! Schwann cell development GO:0014044 15 6 0,000 0,02951624 0,08932841 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02951624 0,08921618 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02951624 0,08910424 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02951624 0,08899259 ! subpallium development GO:0021544 10 6 0,000 0,02951624 0,08888121 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02951624 0,0887701 ! histone ubiquitination GO:0016574 8 6 0,000 0,02951624 0,08865928 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02951624 0,08854873 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02951624 0,08843846 ! G2 phase GO:0051319 16 6 0,000 0,02951624 0,08832846 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02951624 0,08821874 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02951624 0,08810928 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02951624 0,0880001 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02951624 0,08789119 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02951624 0,08778255 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02951624 0,08767418 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02951624 0,08756607 ! receptor internalization GO:0031623 10 6 0,000 0,02951624 0,08745823 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02951624 0,08735066 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02951624 0,08724335 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02951624 0,0871363 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02951624 0,08702951 ! protein deubiquitination GO:0016579 14 6 0,000 0,02951624 0,08692299 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02951624 0,08681673 ! protein destabilization GO:0031648 9 6 0,000 0,02951624 0,08671072 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02951624 0,08660498 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02951624 0,08649949 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02951624 0,08639426 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02951624 0,08628929 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02951624 0,08618457 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02951624 0,0860801 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02951624 0,08597589 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02951624 0,08587193 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02951624 0,08576822 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02951624 0,08566476 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02951624 0,08556155 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02951624 0,08545858 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02951624 0,08535587 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02951624 0,0852534 ! catecholamine transport GO:0051937 9 6 0,000 0,02951624 0,08515118 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02951624 0,0850492 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02951624 0,08494747 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02951624 0,08484598 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02951624 0,08474473 ! maternal placenta development GO:0001893 12 6 0,000 0,02951624 0,08464372 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02951624 0,08454296 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02951624 0,08444243 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02951624 0,08434214 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02951624 0,08424209 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02951624 0,08414228 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02978084 0,08479609 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03080546 0,08760986 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03080546 0,08750643 ! aging GO:0007568 103 55 1,000 0,03080546 0,08740323 ! heart morphogenesis GO:0003007 97 55 1,000 0,03080546 0,08730029 ! nuclear export GO:0051168 97 55 1,000 0,03080546 0,08719758 ! regulation of DNA replication GO:0006275 101 56 1,000 0,03184393 0,09003112 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03289606 0,09289663 ! maintenance of location GO:0051235 118 57 1,000 0,03289606 0,09278772 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,03396172 0,09568137 ! tRNA transcription GO:0009304 14 7 0,000 0,03435078 0,09666429 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03435078 0,09655136 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03435078 0,0964387 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03435078 0,0963263 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03435078 0,09621416 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03435078 0,09610228 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03435078 0,09599067 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03435078 0,09587931 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03435078 0,09576821 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03435078 0,09565737 ! prostate gland development GO:0030850 13 7 0,000 0,03435078 0,09554678 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03435078 0,09543645 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03435078 0,09532637 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03435078 0,09521655 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03435078 0,09510698 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03435078 0,09499766 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03435078 0,09488859 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03435078 0,09477978 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03435078 0,09467121 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03435078 0,09456289 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03435078 0,09445482 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03435078 0,09434699 ! glycolipid transport GO:0046836 10 7 0,000 0,03435078 0,09423941 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03435078 0,09413208 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03435078 0,09402499 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03435078 0,09391814 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03435078 0,09381154 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03435078 0,09370518 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03435078 0,09359905 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03435078 0,09349317 ! mRNA stabilization GO:0048255 18 7 0,000 0,03435078 0,09338753 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03435078 0,09328213 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03435078 0,09317696 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03435078 0,09307203 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03435078 0,09296734 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03435078 0,09286288 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03435078 0,09275866 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03435078 0,09265467 ! lipoprotein transport GO:0042953 14 7 0,000 0,03435078 0,09255091 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03435078 0,09244739 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03435078 0,09234409 ! rhythmic behavior GO:0007622 15 7 0,000 0,03435078 0,09224103 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03435078 0,0921382 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03435078 0,0920356 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03435078 0,09193322 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03435078 0,09183107 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03435078 0,09172915 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03435078 0,09162746 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03435078 0,09152599 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03435078 0,09142474 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03435078 0,09132372 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03435078 0,09122292 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03435078 0,09112234 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03435078 0,09102199 ! spinal cord patterning GO:0021511 13 7 0,000 0,03435078 0,09092185 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03435078 0,09082194 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03435078 0,09072224 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03435078 0,09062277 ! adrenal gland development GO:0030325 17 7 0,000 0,03435078 0,09052351 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03435078 0,09042447 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03435078 0,09032564 ! ovulation GO:0030728 9 7 0,000 0,03435078 0,09022704 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03435078 0,09012864 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03435078 0,09003046 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03435078 0,0899325 ! microtubule nucleation GO:0007020 20 7 0,000 0,03435078 0,08983474 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03435078 0,0897372 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03435078 0,08963987 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03435078 0,08954276 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03435078 0,08944585 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03435078 0,08934915 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03435078 0,08925266 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03435078 0,08915638 ! galactose metabolic process GO:0006012 13 7 0,000 0,03435078 0,08906031 ! vesicle fusion GO:0006906 17 7 0,000 0,03435078 0,08896444 ! response to dietary excess GO:0002021 8 7 0,000 0,03435078 0,08886878 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03435078 0,08877332 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03435078 0,08867807 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03435078 0,08858303 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03435078 0,08848818 ! organ growth GO:0035265 15 7 0,000 0,03435078 0,08839355 ! purine salvage GO:0043101 10 7 0,000 0,03435078 0,08829911 ! nucleoside transport GO:0015858 8 7 0,000 0,03435078 0,08820487 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03435078 0,08811084 ! parturition GO:0007567 14 7 0,000 0,03435078 0,088017 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03435078 0,08792337 ! rRNA modification GO:0000154 14 7 0,000 0,03435078 0,08782993 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03435078 0,08773669 ! spindle checkpoint GO:0031577 15 7 0,000 0,03435078 0,08764365 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03435078 0,08755081 ! macrophage differentiation GO:0030225 11 7 0,000 0,03435078 0,08745816 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03435078 0,08736571 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03435078 0,08727346 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03435078 0,0871814 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03435078 0,08708953 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03435078 0,08699786 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03435078 0,08690638 ! fibrinolysis GO:0042730 10 7 0,000 0,03435078 0,08681509 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03435078 0,08672399 ! eating behavior GO:0042755 7 7 0,000 0,03435078 0,08663309 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03435078 0,08654237 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03435078 0,08645185 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03435078 0,08636151 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03435078 0,08627136 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03435078 0,0861814 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03435078 0,08609163 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03435078 0,08600204 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03435078 0,08591265 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03435078 0,08582343 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03435078 0,0857344 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03435078 0,08564556 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03435078 0,0855569 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03435078 0,08546842 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03435078 0,08538013 ! regulation of meiosis GO:0040020 12 7 0,000 0,03435078 0,08529202 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03435078 0,08520409 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03435078 0,08511634 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03435078 0,08502877 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03435078 0,08494138 ! transcription termination GO:0006353 13 7 0,000 0,03435078 0,08485417 ! response to tumor cell GO:0002347 13 7 0,000 0,03435078 0,08476714 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03435078 0,08468029 ! anaphase GO:0051322 17 7 0,000 0,03435078 0,08459362 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03435078 0,08450712 ! axonal fasciculation GO:0007413 18 7 0,000 0,03435078 0,0844208 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03435078 0,08433466 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03435078 0,08424869 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03435078 0,0841629 ! diuresis GO:0030146 12 7 0,000 0,03435078 0,08407728 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03435078 0,08399183 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03435078 0,08390656 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03435078 0,08382147 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03435078 0,08373654 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03435078 0,08365179 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03435078 0,0835672 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03435078 0,08348279 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03435078 0,08339855 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03435078 0,08331448 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03435078 0,08323058 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03435078 0,08314685 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03435078 0,08306328 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03435078 0,08297988 ! lymph node development GO:0048535 10 7 0,000 0,03435078 0,08289665 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03435078 0,08281359 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03435078 0,0827307 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03435078 0,08264796 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03435078 0,0825654 ! adult feeding behavior GO:0008343 9 7 0,000 0,03435078 0,082483 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03435078 0,08240076 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03435078 0,08231869 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03435078 0,08223678 ! muscle adaptation GO:0043500 14 7 0,000 0,03435078 0,08215503 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03435078 0,08207345 ! retina homeostasis GO:0001895 12 7 0,000 0,03435078 0,08199203 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03435078 0,08191077 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03435078 0,08182967 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03435078 0,08174873 ! protein prenylation GO:0018342 18 7 0,000 0,03435078 0,08166795 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03435078 0,08158733 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03504073 0,08314397 ! DNA catabolic process GO:0006308 86 59 1,000 0,03504073 0,08306206 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,03504073 0,0829803 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03504073 0,08289871 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,03613294 0,08539867 ! kidney development GO:0001822 122 60 1,000 0,03613294 0,08531486 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,03723819 0,08783831 ! ear development GO:0043583 103 62 1,000 0,03835633 0,09038719 ! viral reproductive process GO:0022415 126 62 1,000 0,03835633 0,09029875 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03916138 0,0921039 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03916138 0,09201395 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03916138 0,09192418 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03916138 0,09183459 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03916138 0,09174517 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03916138 0,09165592 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03916138 0,09156685 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03916138 0,09147795 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03916138 0,09138922 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03916138 0,09130066 ! meiotic prophase I GO:0007128 13 8 0,000 0,03916138 0,09121228 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03916138 0,09112407 ! oligopeptide transport GO:0006857 15 8 0,000 0,03916138 0,09103602 ! UTP metabolic process GO:0046051 8 8 0,000 0,03916138 0,09094815 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03916138 0,09086045 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03916138 0,09077291 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03916138 0,09068555 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03916138 0,09059835 ! succinate metabolic process GO:0006105 14 8 0,000 0,03916138 0,09051132 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03916138 0,09042446 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03916138 0,09033776 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03916138 0,09025123 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03916138 0,09016487 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03916138 0,09007867 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03916138 0,08999263 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03916138 0,08990676 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03916138 0,08982105 ! reflex GO:0060004 16 8 0,000 0,03916138 0,08973551 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03916138 0,08965013 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03916138 0,08956491 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03916138 0,08947985 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03916138 0,08939496 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03916138 0,08931022 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03916138 0,08922565 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03916138 0,08914124 ! pigment granule organization GO:0048753 16 8 0,000 0,03916138 0,08905698 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03916138 0,08897289 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03916138 0,08888895 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03916138 0,08880517 ! histidine metabolic process GO:0006547 16 8 0,000 0,03916138 0,08872155 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03916138 0,08863809 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03916138 0,08855478 ! glycine catabolic process GO:0006546 13 8 0,000 0,03916138 0,08847163 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03916138 0,08838864 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03916138 0,0883058 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03916138 0,08822311 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03916138 0,08814059 ! melanin metabolic process GO:0006582 15 8 0,000 0,03916138 0,08805821 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03916138 0,08797599 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03916138 0,08789392 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03916138 0,08781201 ! macrophage activation GO:0042116 12 8 0,000 0,03916138 0,08773025 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03916138 0,08764864 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03916138 0,08756718 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03916138 0,08748587 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03916138 0,08740472 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03916138 0,08732371 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03916138 0,08724286 ! osteoblast development GO:0002076 16 8 0,000 0,03916138 0,08716215 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03916138 0,08708159 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03916138 0,08700119 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03916138 0,08692093 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03916138 0,08684082 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03916138 0,08676085 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03916138 0,08668104 ! response to UV-B GO:0010224 16 8 0,000 0,03916138 0,08660137 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03916138 0,08652184 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03916138 0,08644246 ! intermediate filament organization GO:0045109 12 8 0,000 0,03916138 0,08636323 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03916138 0,08628414 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03916138 0,0862052 ! cellular extravasation GO:0045123 12 8 0,000 0,03916138 0,0861264 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03916138 0,08604775 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03916138 0,08596924 ! response to antibiotic GO:0046677 11 8 0,000 0,03916138 0,08589087 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03916138 0,08581265 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03916138 0,08573456 ! DNA topological change GO:0006265 12 8 0,000 0,03916138 0,08565662 ! response to tropane GO:0014073 15 8 0,000 0,03916138 0,08557882 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03916138 0,08550117 ! melanosome transport GO:0032402 13 8 0,000 0,03916138 0,08542365 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03916138 0,08534627 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03916138 0,08526904 ! mast cell activation GO:0045576 14 8 0,000 0,03916138 0,08519194 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03916138 0,08511498 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03916138 0,08503816 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03916138 0,08496148 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03916138 0,08488494 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03916138 0,08480854 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03916138 0,08473227 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03916138 0,08465614 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03916138 0,08458015 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03916138 0,08450429 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03916138 0,08442857 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03916138 0,08435299 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03916138 0,08427754 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03916138 0,08420222 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03916138 0,08412704 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03916138 0,08405199 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03916138 0,08397708 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03916138 0,0839023 ! hormone catabolic process GO:0042447 17 8 0,000 0,03916138 0,08382766 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03916138 0,08375314 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03916138 0,08367876 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03916138 0,08360451 ! ATP catabolic process GO:0006200 11 8 0,000 0,03916138 0,0835304 ! blastocyst growth GO:0001832 19 8 0,000 0,03916138 0,08345641 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03916138 0,08338255 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03916138 0,08330883 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03916138 0,08323523 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03916138 0,08316177 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03916138 0,08308844 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03916138 0,08301523 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03916138 0,08294215 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03916138 0,0828692 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03916138 0,08279638 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03916138 0,08272369 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03916138 0,08265113 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03916138 0,08257869 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03916138 0,08250638 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03916138 0,0824342 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03916138 0,08236214 ! regulation of mitosis GO:0007088 105 63 1,000 0,0394872 0,08297485 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,0394872 0,08290245 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,04178654 0,08765337 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,0429547 0,09002528 ! cell projection assembly GO:0030031 120 66 1,000 0,0429547 0,08994693 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04394818 0,09194724 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04394818 0,09186736 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04394818 0,09178761 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04394818 0,091708 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04394818 0,09162853 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04394818 0,0915492 ! phosphate transport GO:0006817 19 9 0,000 0,04394818 0,09147001 ! reproductive behavior GO:0019098 19 9 0,000 0,04394818 0,09139095 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04394818 0,09131203 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04394818 0,09123324 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04394818 0,09115459 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04394818 0,09107608 ! GTP metabolic process GO:0046039 9 9 0,000 0,04394818 0,0909977 ! RNA methylation GO:0001510 15 9 0,000 0,04394818 0,09091946 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04394818 0,09084135 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04394818 0,09076337 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04394818 0,09068553 ! artery development GO:0060840 24 9 0,000 0,04394818 0,09060782 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04394818 0,09053025 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04394818 0,0904528 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04394818 0,09037549 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04394818 0,09029832 ! chemosensory behavior GO:0007635 20 9 0,000 0,04394818 0,09022127 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04394818 0,09014436 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04394818 0,09006757 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04394818 0,08999092 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04394818 0,0899144 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04394818 0,089838 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04394818 0,08976174 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04394818 0,08968561 ! protein targeting to ER GO:0045047 22 9 0,000 0,04394818 0,0896096 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04394818 0,08953372 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04394818 0,08945798 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04394818 0,08938236 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04394818 0,08930687 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04394818 0,0892315 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04394818 0,08915626 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04394818 0,08908115 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04394818 0,08900617 ! mannose metabolic process GO:0006013 13 9 0,000 0,04394818 0,08893131 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04394818 0,08885658 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04394818 0,08878197 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04394818 0,08870749 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04394818 0,08863313 ! ruffle organization GO:0031529 15 9 0,000 0,04394818 0,0885589 ! retinol metabolic process GO:0042572 18 9 0,000 0,04394818 0,08848479 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04394818 0,08841081 ! behavioral fear response GO:0001662 22 9 0,000 0,04394818 0,08833695 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04394818 0,08826321 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04394818 0,0881896 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04394818 0,08811611 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04394818 0,08804274 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04394818 0,08796949 ! segment specification GO:0007379 13 9 0,000 0,04394818 0,08789637 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04394818 0,08782336 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04394818 0,08775048 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04394818 0,08767772 ! response to amine stimulus GO:0014075 13 9 0,000 0,04394818 0,08760508 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04394818 0,08753256 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04394818 0,08746016 ! erythrocyte development GO:0048821 15 9 0,000 0,04394818 0,08738788 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04394818 0,08731571 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04394818 0,08724367 ! renal water homeostasis GO:0003091 14 9 0,000 0,04394818 0,08717175 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04394818 0,08709994 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04394818 0,08702825 ! icosanoid secretion GO:0032309 15 9 0,000 0,04394818 0,08695669 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04394818 0,08688523 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04394818 0,0868139 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04394818 0,08674268 ! regulation of cell division GO:0051302 15 9 0,000 0,04394818 0,08667158 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04394818 0,0866006 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04394818 0,08652973 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04394818 0,08645898 ! sterol catabolic process GO:0016127 11 9 0,000 0,04394818 0,08638834 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04394818 0,08631782 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04394818 0,08624741 ! S phase GO:0051320 9 9 0,000 0,04394818 0,08617712 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04394818 0,08610695 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04394818 0,08603688 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04394818 0,08596693 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04394818 0,0858971 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04394818 0,08582738 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04394818 0,08575777 ! purine base metabolic process GO:0006144 21 9 0,000 0,04394818 0,08568827 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04394818 0,08561889 ! pigment granule transport GO:0051904 17 9 0,000 0,04394818 0,08554962 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04394818 0,08548046 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04394818 0,08541141 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04394818 0,08534248 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04394818 0,08527365 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04394818 0,08520494 ! mitochondrion localization GO:0051646 15 9 0,000 0,04394818 0,08513634 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,044135 0,08542945 ! lung development GO:0030324 144 67 1,000 0,044135 0,08536078 ! chromosome segregation GO:0007059 113 67 1,000 0,044135 0,08529221 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,044135 0,08522376 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,044135 0,08515542 ! activation of immune response GO:0002253 105 67 1,000 0,044135 0,08508719 ! viral reproduction GO:0016032 134 68 1,000 0,04532727 0,08731579 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,04532727 0,08724594 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,04653139 0,08949202 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,04653139 0,08942054 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,04653139 0,08934917 ! urogenital system development GO:0001655 137 69 1,000 0,04653139 0,08927792 ! appendage morphogenesis GO:0035107 135 70 1,000 0,04774719 0,09153763 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,04774719 0,09146475 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0487113 0,09323737 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0487113 0,09316326 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0487113 0,09308926 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0487113 0,09301538 ! synapsis GO:0007129 13 10 0,000 0,0487113 0,09294161 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0487113 0,09286797 ! N-glycan processing GO:0006491 20 10 0,000 0,0487113 0,09279444 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0487113 0,09272103 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0487113 0,09264773 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0487113 0,09257455 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0487113 0,09250148 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0487113 0,09242853 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0487113 0,09235569 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0487113 0,09228297 ! androgen metabolic process GO:0008209 17 10 0,000 0,0487113 0,09221037 ! phospholipid efflux GO:0033700 16 10 0,000 0,0487113 0,09213787 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0487113 0,0920655 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0487113 0,09199323 ! lung alveolus development GO:0048286 26 10 0,000 0,0487113 0,09192108 ! pathogenesis GO:0009405 13 10 0,000 0,0487113 0,09184904 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0487113 0,09177712 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0487113 0,0917053 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0487113 0,0916336 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0487113 0,09156201 ! endoderm development GO:0007492 16 10 0,000 0,0487113 0,09149054 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0487113 0,09141917 ! arginine catabolic process GO:0006527 13 10 0,000 0,0487113 0,09134792 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0487113 0,09127677 ! proline metabolic process GO:0006560 13 10 0,000 0,0487113 0,09120574 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0487113 0,09113482 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0487113 0,09106401 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0487113 0,0909933 ! V(D)J recombination GO:0033151 28 10 0,000 0,0487113 0,09092271 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0487113 0,09085223 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0487113 0,09078186 ! B cell proliferation GO:0042100 18 10 0,000 0,0487113 0,09071159 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0487113 0,09064144 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0487113 0,09057139 ! multicellular organism growth GO:0035264 18 10 0,000 0,0487113 0,09050145 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0487113 0,09043162 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0487113 0,09036189 ! epithelial cell development GO:0002064 20 10 0,000 0,0487113 0,09029228 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0487113 0,09022277 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0487113 0,09015337 ! macroautophagy GO:0016236 17 10 0,000 0,0487113 0,09008407 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0487113 0,09001488 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0487113 0,0899458 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0487113 0,08987682 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0487113 0,08980795 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0487113 0,08973919 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0487113 0,08967053 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0487113 0,08960197 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0487113 0,08953352 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0487113 0,08946517 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0487113 0,08939693 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0487113 0,08932879 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0487113 0,08926076 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0487113 0,08919283 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0487113 0,089125 ! response to dsRNA GO:0043331 20 10 0,000 0,0487113 0,08905728 ! DNA ligation GO:0006266 19 10 0,000 0,0487113 0,08898966 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0487113 0,08892214 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0487113 0,08885472 ! melanosome localization GO:0032400 16 10 0,000 0,0487113 0,08878741 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0487113 0,08872019 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0487113 0,08865308 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0487113 0,08858607 ! mRNA cleavage GO:0006379 17 10 0,000 0,0487113 0,08851917 ! protein sumoylation GO:0016925 15 10 0,000 0,0487113 0,08845236 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0487113 0,08838565 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0487113 0,08831905 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0487113 0,08825254 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0487113 0,08818614 ! salivary gland development GO:0007431 27 10 0,000 0,0487113 0,08811983 ! prophase GO:0051324 15 10 0,000 0,0487113 0,08805363 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0487113 0,08798752 ! apical protein localization GO:0045176 15 10 0,000 0,0487113 0,08792151 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0487113 0,0878556 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0487113 0,08778979 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0487113 0,08772408 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0487113 0,08765847 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0487113 0,08759296 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0487113 0,08752754 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0487113 0,08746222 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0487113 0,087397 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0487113 0,08733187 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0487113 0,08726685 ! detection of calcium ion GO:0005513 23 10 0,000 0,0487113 0,08720192 ! oocyte development GO:0048599 17 10 0,000 0,0487113 0,08713708 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0487113 0,08707234 ! blastocyst formation GO:0001825 17 10 0,000 0,0487113 0,0870077 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0487113 0,08694316 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0487113 0,08687871 ! activation of innate immune response GO:0002218 12 10 0,000 0,0487113 0,08681435 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0487113 0,08675009 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0487113 0,08668593 ! response to nicotine GO:0035094 20 10 0,000 0,0487113 0,08662186 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0487113 0,08655788 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0487113 0,086494 ! appendage development GO:0048736 136 71 1,000 0,04897453 0,08689729 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,04897453 0,08683325 ! regulation of immune effector process GO:0002697 137 71 1,000 0,04897453 0,08676931 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,05021328 0,08889856 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,05021328 0,0888332 ! respiratory system development GO:0060541 153 72 1,000 0,05021328 0,08876793 ! axon guidance GO:0007411 139 73 1,000 0,05146329 0,09091091 ! transition metal ion transport GO:0000041 126 74 1,000 0,05272441 0,09307038 ! meiosis GO:0007126 121 74 1,000 0,05272441 0,09300215 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 1,000 0,05272441 0,09293401 ! respiratory burst GO:0045730 17 11 0,000 0,05345083 0,09414547 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05345083 0,0940766 ! neuron fate specification GO:0048665 17 11 0,000 0,05345083 0,09400783 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05345083 0,09393916 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05345083 0,09387059 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05345083 0,09380212 ! thyroid gland development GO:0030878 26 11 0,000 0,05345083 0,09373375 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05345083 0,09366548 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05345083 0,09359731 ! response to pain GO:0048265 24 11 0,000 0,05345083 0,09352924 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05345083 0,09346127 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05345083 0,0933934 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05345083 0,09332562 ! bone resorption GO:0045453 16 11 0,000 0,05345083 0,09325795 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05345083 0,09319037 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05345083 0,09312289 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05345083 0,0930555 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05345083 0,09298822 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05345083 0,09292103 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05345083 0,09285394 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05345083 0,09278695 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05345083 0,09272005 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05345083 0,09265325 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05345083 0,09258654 ! lipid digestion GO:0044241 18 11 0,000 0,05345083 0,09251993 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05345083 0,09245342 ! UV protection GO:0009650 19 11 0,000 0,05345083 0,092387 ! adult heart development GO:0007512 14 11 0,000 0,05345083 0,09232068 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05345083 0,09225445 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05345083 0,09218832 ! temperature homeostasis GO:0001659 17 11 0,000 0,05345083 0,09212228 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05345083 0,09205634 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05345083 0,09199049 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05345083 0,09192474 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05345083 0,09185908 ! regulation of organ growth GO:0046620 13 11 0,000 0,05345083 0,09179351 ! pigment granule localization GO:0051875 20 11 0,000 0,05345083 0,09172804 ! vasoconstriction GO:0042310 18 11 0,000 0,05345083 0,09166266 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05345083 0,09159737 ! embryonic axis specification GO:0000578 18 11 0,000 0,05345083 0,09153218 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05345083 0,09146708 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05345083 0,09140207 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05345083 0,09133715 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05345083 0,09127233 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05345083 0,09120759 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05345083 0,09114295 ! zymogen activation GO:0031638 15 11 0,000 0,05345083 0,0910784 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05345083 0,09101395 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05345083 0,09094958 ! nucleosome positioning GO:0016584 15 11 0,000 0,05345083 0,09088531 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05345083 0,09082112 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05345083 0,09075703 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05345083 0,09069302 ! acid secretion GO:0046717 18 11 0,000 0,05345083 0,09062911 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05345083 0,09056529 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05345083 0,09050155 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05345083 0,09043791 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05345083 0,09037436 ! oocyte differentiation GO:0009994 18 11 0,000 0,05345083 0,09031089 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05345083 0,09024751 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05345083 0,09018423 ! cholesterol efflux GO:0033344 19 11 0,000 0,05345083 0,09012103 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05345083 0,09005792 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05345083 0,0899949 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05345083 0,08993196 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05345083 0,08986912 ! embryonic gut development GO:0048566 15 11 0,000 0,05345083 0,08980636 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05345083 0,08974369 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05345083 0,08968111 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05345083 0,08961861 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05345083 0,0895562 ! defense response to fungus GO:0050832 13 11 0,000 0,05345083 0,08949388 ! developmental induction GO:0031128 19 11 0,000 0,05345083 0,08943165 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05345083 0,0893695 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05345083 0,08930744 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05345083 0,08924546 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05345083 0,08918357 ! nucleus localization GO:0051647 19 11 0,000 0,05345083 0,08912177 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05345083 0,08906005 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,05399651 0,08990699 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,05399651 0,08984482 ! meiotic cell cycle GO:0051321 122 75 1,000 0,05399651 0,08978273 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,05527945 0,09185246 ! defense response to bacterium GO:0042742 89 76 1,000 0,05527945 0,09178907 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,05657309 0,09387232 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05816692 0,09645045 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05816692 0,09638402 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05816692 0,09631769 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05816692 0,09625145 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05816692 0,09618529 ! cartilage condensation GO:0001502 20 12 0,000 0,05816692 0,09611923 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05816692 0,09605326 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05816692 0,09598738 ! protein complex disassembly GO:0043241 27 12 0,000 0,05816692 0,09592159 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,05816692 0,09585589 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05816692 0,09579028 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05816692 0,09572476 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05816692 0,09565933 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05816692 0,09559399 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05816692 0,09552874 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05816692 0,09546358 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05816692 0,0953985 ! drug transport GO:0015893 16 12 0,000 0,05816692 0,09533352 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05816692 0,09526862 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05816692 0,09520381 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05816692 0,09513909 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05816692 0,09507446 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05816692 0,09500991 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05816692 0,09494546 ! forebrain cell migration GO:0021885 21 12 0,000 0,05816692 0,09488109 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05816692 0,0948168 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05816692 0,09475261 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 0,000 0,05816692 0,0946885 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05816692 0,09462448 ! monoamine transport GO:0015844 18 12 0,000 0,05816692 0,09456054 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05816692 0,09449669 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05816692 0,09443293 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05816692 0,09436925 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05816692 0,09430566 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05816692 0,09424216 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05816692 0,09417874 ! protein homotetramerization GO:0051289 21 12 0,000 0,05816692 0,0941154 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05816692 0,09405215 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05816692 0,09398899 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05816692 0,09392591 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05816692 0,09386291 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05816692 0,0938 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05816692 0,09373717 ! cranial nerve development GO:0021545 20 12 0,000 0,05816692 0,09367443 ! fucose catabolic process GO:0019317 22 12 0,000 0,05816692 0,09361177 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05816692 0,0935492 ! histone methylation GO:0016571 26 12 0,000 0,05816692 0,09348671 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05816692 0,0934243 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05816692 0,09336198 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05816692 0,09329973 ! T cell homeostasis GO:0043029 25 12 0,000 0,05816692 0,09323758 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05816692 0,0931755 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05816692 0,09311351 ! spleen development GO:0048536 22 12 0,000 0,05816692 0,0930516 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05816692 0,09298977 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05816692 0,09292802 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05816692 0,09286636 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05816692 0,09280478 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05816692 0,09274327 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05816692 0,09268186 ! response to cold GO:0009409 17 12 0,000 0,05816692 0,09262052 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05816692 0,09255926 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05816692 0,09249808 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,05919194 0,09406592 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,05919194 0,09400383 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,06051687 0,09604458 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,06185195 0,09809875 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,06185195 0,09803413 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06285966 0,09956572 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06285966 0,09950022 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06285966 0,0994348 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06285966 0,09936947 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06285966 0,09930423 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06285966 0,09923907 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06285966 0,09917399 ! organelle fusion GO:0048284 32 13 0,000 0,06285966 0,099109 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06285966 0,0990441 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06285966 0,09897928 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06285966 0,09891454 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06285966 0,09884989 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06285966 0,09878533 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06285966 0,09872085 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06285966 0,09865645 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06285966 0,09859214 ! methionine metabolic process GO:0006555 27 13 0,000 0,06285966 0,09852791 ! plasma membrane organization GO:0007009 24 13 0,000 0,06285966 0,09846376 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06285966 0,0983997 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06285966 0,09833572 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06285966 0,09827182 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06285966 0,09820801 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06285966 0,09814428 ! response to X-ray GO:0010165 25 13 0,000 0,06285966 0,09808063 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06285966 0,09801707 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06285966 0,09795359 ! exocrine system development GO:0035272 32 13 0,000 0,06285966 0,09789019 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06285966 0,09782687 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06285966 0,09776363 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06285966 0,09770048 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06285966 0,0976374 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06285966 0,09757441 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06285966 0,0975115 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06285966 0,09744867 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06285966 0,09738592 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06285966 0,09732325 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06285966 0,09726067 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06285966 0,09719816 ! ribosome assembly GO:0042255 17 13 0,000 0,06285966 0,09713573 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06285966 0,09707339 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06285966 0,09701112 ! chromatin silencing GO:0006342 26 13 0,000 0,06285966 0,09694893 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06285966 0,09688683 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06285966 0,0968248 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06285966 0,09676285 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06285966 0,09670098 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06285966 0,09663919 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06285966 0,09657748 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06285966 0,09651585 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06285966 0,0964543 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06285966 0,09639282 ! embryonic placenta development GO:0001892 23 13 0,000 0,06285966 0,09633142 ! insulin secretion GO:0030073 23 13 0,000 0,06285966 0,09627011 ! actin filament polymerization GO:0030041 24 13 0,000 0,06285966 0,09620887 ! acrosome reaction GO:0007340 18 13 0,000 0,06285966 0,0961477 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,06319707 0,09660239 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,06319707 0,09654105 ! regulation of lyase activity GO:0051339 160 83 1,000 0,06455209 0,09854842 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,06591687 0,10056815 ! rRNA transcription GO:0009303 25 14 0,000 0,06752917 0,10296273 ! lactation GO:0007595 26 14 0,000 0,06752917 0,10289752 ! reproductive cellular process GO:0048610 20 14 0,000 0,06752917 0,1028324 ! tRNA modification GO:0006400 20 14 0,000 0,06752917 0,10276735 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06752917 0,10270239 ! water transport GO:0006833 21 14 0,000 0,06752917 0,10263752 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06752917 0,10257272 ! non-recombinational repair GO:0000726 25 14 0,000 0,06752917 0,102508 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06752917 0,10244337 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06752917 0,10237882 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06752917 0,10231435 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06752917 0,10224996 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06752917 0,10218565 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06752917 0,10212142 ! palate development GO:0060021 31 14 0,000 0,06752917 0,10205728 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06752917 0,10199321 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06752917 0,10192923 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06752917 0,10186532 ! arginine metabolic process GO:0006525 17 14 0,000 0,06752917 0,1018015 ! regulation of heart rate GO:0002027 24 14 0,000 0,06752917 0,10173775 ! organic alcohol transport GO:0015850 29 14 0,000 0,06752917 0,10167408 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06752917 0,1016105 ! embryo implantation GO:0007566 30 14 0,000 0,06752917 0,10154699 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06752917 0,10148356 ! L-amino acid transport GO:0015807 30 14 0,000 0,06752917 0,10142022 ! bone mineralization GO:0030282 17 14 0,000 0,06752917 0,10135695 ! stem cell development GO:0048864 43 14 0,000 0,06752917 0,10129376 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06752917 0,10123065 ! cerebellum development GO:0021549 21 14 0,000 0,06752917 0,10116761 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06752917 0,10110466 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06752917 0,10104178 ! response to gamma radiation GO:0010332 28 14 0,000 0,06752917 0,10097898 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06752917 0,10091627 ! cofactor transport GO:0051181 26 14 0,000 0,06752917 0,10085362 ! NADP metabolic process GO:0006739 24 14 0,000 0,06752917 0,10079106 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06752917 0,10072857 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06752917 0,10066616 ! intestinal absorption GO:0050892 25 14 0,000 0,06752917 0,10060383 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06752917 0,10054158 ! oxygen transport GO:0015671 21 14 0,000 0,06752917 0,1004794 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06752917 0,1004173 ! male genitalia development GO:0030539 24 14 0,000 0,06752917 0,10035527 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06752917 0,10029333 ! regulation of axon extension GO:0030516 37 14 0,000 0,06752917 0,10023145 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,06752917 0,10016966 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06752917 0,10010794 ! mitochondrion organization GO:0007005 148 86 1,000 0,06867521 0,10174418 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,07006851 0,10374451 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07217557 0,10679854 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07217557 0,1067329 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07217557 0,10666734 ! superoxide anion generation GO:0042554 20 15 0,000 0,07217557 0,10660186 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07217557 0,10653646 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07217557 0,10647114 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07217557 0,1064059 ! copper ion transport GO:0006825 20 15 0,000 0,07217557 0,10634074 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07217557 0,10627566 ! sulfate transport GO:0008272 23 15 0,000 0,07217557 0,10621066 ! response to cAMP GO:0051591 22 15 0,000 0,07217557 0,10614574 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07217557 0,1060809 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07217557 0,10601613 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07217557 0,10595145 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07217557 0,10588685 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07217557 0,10582232 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07217557 0,10575787 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07217557 0,10569351 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07217557 0,10562921 ! pituitary gland development GO:0021983 29 15 0,000 0,07217557 0,105565 ! vesicle coating GO:0006901 33 15 0,000 0,07217557 0,10550087 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07217557 0,10543681 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07217557 0,10537283 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07217557 0,10530893 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07217557 0,10524511 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07217557 0,10518136 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07217557 0,10511769 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07217557 0,1050541 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07217557 0,10499059 ! histone deacetylation GO:0016575 20 15 0,000 0,07217557 0,10492715 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07217557 0,10486379 ! tissue regeneration GO:0042246 26 15 0,000 0,07217557 0,1048005 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07217557 0,10473729 ! water homeostasis GO:0030104 27 15 0,000 0,07217557 0,10467416 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07217557 0,1046111 ! muscle maintenance GO:0046716 26 15 0,000 0,07217557 0,10454812 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07217557 0,10448522 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07217557 0,10442239 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07217557 0,10435963 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07217557 0,10429695 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07217557 0,10423435 ! cell killing GO:0001906 29 15 0,000 0,07217557 0,10417182 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07217557 0,10410937 ! detection of bacterium GO:0016045 18 15 0,000 0,07217557 0,10404699 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07217557 0,10398469 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07217557 0,10392246 ! peptide hormone processing GO:0016486 23 15 0,000 0,07217557 0,1038603 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,07430345 0,1068584 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07679898 0,11038132 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07679898 0,11031542 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07679898 0,1102496 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07679898 0,11018386 ! bone remodeling GO:0046849 27 16 0,000 0,07679898 0,1101182 ! filopodium assembly GO:0046847 32 16 0,000 0,07679898 0,11005261 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07679898 0,1099871 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07679898 0,10992167 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07679898 0,10985632 ! startle response GO:0001964 28 16 0,000 0,07679898 0,10979105 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07679898 0,10972585 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07679898 0,10966073 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07679898 0,10959569 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07679898 0,10953073 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07679898 0,10946584 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07679898 0,10940103 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07679898 0,10933629 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07679898 0,10927164 ! response to osmotic stress GO:0006970 25 16 0,000 0,07679898 0,10920705 ! lysosomal transport GO:0007041 26 16 0,000 0,07679898 0,10914255 ! fructose metabolic process GO:0006000 25 16 0,000 0,07679898 0,10907812 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07679898 0,10901377 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07679898 0,10894949 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07679898 0,10888529 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07679898 0,10882116 ! axon cargo transport GO:0008088 43 16 0,000 0,07679898 0,10875711 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07679898 0,10869314 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07679898 0,10862924 ! DNA replication initiation GO:0006270 27 16 0,000 0,07679898 0,10856541 ! neuron recognition GO:0008038 35 16 0,000 0,07679898 0,10850166 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07679898 0,10843799 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07679898 0,10837439 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07679898 0,10831086 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07679898 0,10824741 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,07679898 0,10818404 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07679898 0,10812073 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07679898 0,10805751 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07679898 0,10799435 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07679898 0,10793127 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07679898 0,10786826 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07679898 0,10780533 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,07861834 0,11029488 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,07861834 0,11023061 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,07861834 0,11016641 ! metencephalon development GO:0022037 30 17 0,000 0,08139949 0,11399719 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08139949 0,11393088 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08139949 0,11386464 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08139949 0,11379848 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08139949 0,11373239 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08139949 0,11366638 ! glial cell development GO:0021782 27 17 0,000 0,08139949 0,11360045 ! limbic system development GO:0021761 36 17 0,000 0,08139949 0,1135346 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08139949 0,11346882 ! adult walking behavior GO:0007628 33 17 0,000 0,08139949 0,11340311 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08139949 0,11333749 ! heart looping GO:0001947 30 17 0,000 0,08139949 0,11327194 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08139949 0,11320646 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08139949 0,11314106 ! myoblast differentiation GO:0045445 45 17 0,000 0,08139949 0,11307574 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08139949 0,11301049 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,08139949 0,11294532 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08139949 0,11288022 ! glycine metabolic process GO:0006544 28 17 0,000 0,08139949 0,1128152 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08139949 0,11275025 ! NAD metabolic process GO:0019674 29 17 0,000 0,08139949 0,11268537 ! membrane budding GO:0006900 37 17 0,000 0,08139949 0,11262057 ! DNA integration GO:0015074 29 17 0,000 0,08139949 0,11255585 ! regulation of protein binding GO:0043393 33 17 0,000 0,08139949 0,1124912 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08139949 0,11242662 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08139949 0,11236212 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08139949 0,11229769 ! genitalia development GO:0048806 30 17 0,000 0,08139949 0,11223334 ! neural crest cell migration GO:0001755 37 17 0,000 0,08139949 0,11216906 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08139949 0,11210485 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08139949 0,11204072 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08139949 0,11197666 ! steroid catabolic process GO:0006706 31 17 0,000 0,08139949 0,11191267 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08139949 0,11184876 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08139949 0,11178492 ! gas transport GO:0015669 25 17 0,000 0,08139949 0,11172115 ! organic cation transport GO:0015695 31 17 0,000 0,08139949 0,11165746 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08139949 0,11159383 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08139949 0,11153028 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08139949 0,11146681 ! microspike assembly GO:0030035 36 17 0,000 0,08139949 0,1114034 ! positive regulation of immune response GO:0050778 156 96 1,000 0,08300989 0,1135428 ! protein ubiquitination GO:0016567 217 97 1,000 0,08449022 0,11550197 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08597724 0,11746805 ! neuron maturation GO:0042551 42 18 0,000 0,08597724 0,11740138 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08597724 0,11733479 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08597724 0,11726827 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08597724 0,11720183 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08597724 0,11713546 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08597724 0,11706917 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08597724 0,11700296 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08597724 0,11693682 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08597724 0,11687075 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08597724 0,11680476 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08597724 0,11673884 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08597724 0,116673 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08597724 0,11660723 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08597724 0,11654154 ! response to retinoic acid GO:0032526 26 18 0,000 0,08597724 0,11647592 ! response to fungus GO:0009620 21 18 0,000 0,08597724 0,11641037 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08597724 0,1163449 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08597724 0,1162795 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08597724 0,11621417 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08597724 0,11614892 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08597724 0,11608374 ! vitamin transport GO:0051180 27 18 0,000 0,08597724 0,11601864 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08597724 0,1159536 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08597724 0,11588864 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08597724 0,11582376 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08597724 0,11575894 ! nerve development GO:0021675 28 18 0,000 0,08597724 0,1156942 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08597724 0,11562953 ! response to virus GO:0009615 160 98 1,000 0,0859786 0,11556676 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,08747491 0,11751235 ! protein secretion GO:0009306 39 19 0,000 0,09053232 0,12155176 ! positive regulation of translation GO:0045727 30 19 0,000 0,09053232 0,12148397 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09053232 0,12141625 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09053232 0,12134861 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09053232 0,12128104 ! skin development GO:0043588 36 19 0,000 0,09053232 0,12121355 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09053232 0,12114614 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09053232 0,1210788 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09053232 0,12101153 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09053232 0,12094434 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09053232 0,12087722 ! cerebral cortex development GO:0021987 36 19 0,000 0,09053232 0,12081018 ! pigmentation during development GO:0048066 41 19 0,000 0,09053232 0,12074321 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09053232 0,12067632 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09053232 0,1206095 ! heme metabolic process GO:0042168 36 19 0,000 0,09053232 0,12054275 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09053232 0,12047608 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09053232 0,12040948 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,09053232 0,12034296 ! peptide cross-linking GO:0018149 37 19 0,000 0,09053232 0,12027651 ! heart process GO:0003015 30 19 0,000 0,09053232 0,12021013 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09053232 0,12014383 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09053232 0,12007759 ! visual learning GO:0008542 36 19 0,000 0,09053232 0,12001144 ! cellular pigmentation GO:0033059 36 19 0,000 0,09053232 0,11994535 ! G1 phase GO:0051318 40 19 0,000 0,09053232 0,11987934 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09053232 0,1198134 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09053232 0,11974753 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09053232 0,11968173 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09053232 0,11961601 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09053232 0,11955036 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09053232 0,11948478 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09053232 0,11941927 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09053232 0,11935384 ! cilium assembly GO:0042384 37 19 0,000 0,09053232 0,11928848 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09053232 0,11922318 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09506485 0,12512365 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09506485 0,12505524 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09506485 0,1249869 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09506485 0,12491864 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09506485 0,12485045 ! response to vitamin GO:0033273 31 20 0,000 0,09506485 0,12478234 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09506485 0,1247143 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09506485 0,12464634 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09506485 0,12457845 ! response to alkaloid GO:0043279 38 20 0,000 0,09506485 0,12451063 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09506485 0,12444289 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,09506485 0,12437522 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09506485 0,12430762 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09506485 0,1242401 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09506485 0,12417265 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,09506485 0,12410528 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09506485 0,12403798 ! body fluid secretion GO:0007589 31 20 0,000 0,09506485 0,12397075 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09506485 0,12390359 ! peptide secretion GO:0002790 35 20 0,000 0,09506485 0,12383651 ! stem cell differentiation GO:0048863 53 20 0,000 0,09506485 0,1237695 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09506485 0,12370256 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09506485 0,12363569 ! sensory perception of pain GO:0019233 30 20 0,000 0,09506485 0,1235689 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09506485 0,12350218 ! diencephalon development GO:0021536 34 20 0,000 0,09506485 0,12343553 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09506485 0,12336895 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,09506485 0,12330244 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,09506485 0,12323601 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09506485 0,12316964 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09506485 0,12310335 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09506485 0,12303713 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09506485 0,12297098 ! regulation of glucose import GO:0046324 29 20 0,000 0,09506485 0,12290491 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09506485 0,1228389 ! actin filament-based movement GO:0030048 43 20 0,000 0,09506485 0,12277296 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09506485 0,1227071 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09506485 0,1226413 ! negative regulation of translation GO:0017148 29 20 0,000 0,09506485 0,12257558 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,09506485 0,12250992 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,09506485 0,12244434 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09957494 0,12818476 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09957494 0,12811621 ! hormone secretion GO:0046879 38 21 0,000 0,09957494 0,12804774 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09957494 0,12797933 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09957494 0,12791101 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09957494 0,12784275 ! axis specification GO:0009798 38 21 0,000 0,09957494 0,12777457 ! ovarian follicle development GO:0001541 35 21 0,000 0,09957494 0,12770646 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09957494 0,12763842 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09957494 0,12757045 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09957494 0,12750256 ! cell aging GO:0007569 44 21 0,000 0,09957494 0,12743474 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09957494 0,12736699 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09957494 0,12729932 ! cytolysis GO:0019835 24 21 0,000 0,09957494 0,12723171 ! vasodilation GO:0042311 39 21 0,000 0,09957494 0,12716418 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09957494 0,12709672 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09957494 0,12702933 ! oogenesis GO:0048477 36 21 0,000 0,09957494 0,12696201 ! DNA modification GO:0006304 34 21 0,000 0,09957494 0,12689476 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,09957494 0,12682759 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,09957494 0,12676048 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09957494 0,12669345 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09957494 0,12662649 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09957494 0,12655959 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09957494 0,12649277 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09957494 0,12642602 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09957494 0,12635934 ! collagen catabolic process GO:0030574 28 21 0,000 0,09957494 0,12629273 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09957494 0,12622619 ! gut development GO:0048565 39 21 0,000 0,09957494 0,12615972 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10406271 0,13177625 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10406271 0,13170693 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10406271 0,13163768 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10406271 0,13156851 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10406271 0,13149941 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10406271 0,13143038 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,10406271 0,13136142 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10406271 0,13129254 ! regeneration GO:0031099 41 22 0,000 0,10406271 0,13122373 ! keratinization GO:0031424 28 22 0,000 0,10406271 0,13115499 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10406271 0,13108632 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10406271 0,13101773 ! sensory perception of taste GO:0050909 28 22 0,000 0,10406271 0,1309492 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10406271 0,13088075 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10406271 0,13081237 ! vacuolar transport GO:0007034 36 22 0,000 0,10406271 0,13074406 ! lysosome organization GO:0007040 41 22 0,000 0,10406271 0,13067582 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,10406271 0,13060765 ! fucose metabolic process GO:0006004 39 22 0,000 0,10406271 0,13053956 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10406271 0,13047153 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10406271 0,13040358 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10406271 0,1303357 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10406271 0,13026788 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10406271 0,13020014 ! sarcomere organization GO:0045214 30 22 0,000 0,10406271 0,13013247 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10406271 0,13006487 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10406271 0,12999734 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10406271 0,12992988 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,10852825 0,13543515 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,10852825 0,13536494 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,10852825 0,13529481 ! gluconeogenesis GO:0006094 33 23 0,000 0,10852825 0,13522474 ! viral genome replication GO:0019079 41 23 0,000 0,10852825 0,13515475 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,10852825 0,13508483 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,10852825 0,13501498 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,10852825 0,13494521 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,10852825 0,1348755 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,10852825 0,13480587 ! visual behavior GO:0007632 42 23 0,000 0,10852825 0,13473631 ! response to ethanol GO:0045471 46 23 0,000 0,10852825 0,13466683 ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,10852825 0,13459741 ! peroxisome organization GO:0007031 37 23 0,000 0,10852825 0,13452807 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,10852825 0,13445879 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,10852825 0,13438959 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,10852825 0,13432046 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,10852825 0,1342514 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,10852825 0,13418241 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,10852825 0,1341135 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,10852825 0,13404465 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,10852825 0,13397587 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,10852825 0,13390717 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,10852825 0,13383853 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,10852825 0,13376997 ! fatty acid transport GO:0015908 44 23 0,000 0,10852825 0,13370147 ! platelet activation GO:0030168 37 23 0,000 0,10852825 0,13363305 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,10852825 0,13356469 ! hormone transport GO:0009914 40 23 0,000 0,10852825 0,13349641 ! cell-cell recognition GO:0009988 25 23 0,000 0,10852825 0,13342819 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,10852825 0,13336005 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,10852825 0,13329197 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,10852825 0,13322397 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,10852825 0,13315603 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,11297169 0,13853715 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11297169 0,13846657 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11297169 0,13839607 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11297169 0,13832564 ! vesicle docking GO:0048278 47 24 0,000 0,11297169 0,13825528 ! spinal cord development GO:0021510 47 24 0,000 0,11297169 0,13818499 ! vacuole organization GO:0007033 43 24 0,000 0,11297169 0,13811478 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11297169 0,13804463 ! digestive system process GO:0022600 39 24 0,000 0,11297169 0,13797456 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11297169 0,13790456 ! regulation of behavior GO:0050795 43 24 0,000 0,11297169 0,13783463 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11297169 0,13776477 ! pallium development GO:0021543 49 24 0,000 0,11297169 0,13769498 ! pentose metabolic process GO:0019321 35 24 0,000 0,11297169 0,13762526 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,11297169 0,13755561 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11297169 0,13748603 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11297169 0,13741652 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11297169 0,13734709 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11297169 0,13727772 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11297169 0,13720842 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11297169 0,13713919 ! regulation of amine transport GO:0051952 40 24 0,000 0,11297169 0,13707004 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,11739312 0,14236283 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,11739312 0,14229111 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,11739312 0,14221946 ! phototransduction GO:0007602 33 25 0,000 0,11739312 0,14214789 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,11739312 0,14207639 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,11739312 0,14200496 ! sperm motility GO:0030317 31 25 0,000 0,11739312 0,1419336 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,11739312 0,14186231 ! chromosome condensation GO:0030261 45 25 0,000 0,11739312 0,14179109 ! neural crest cell development GO:0014032 54 25 0,000 0,11739312 0,14171995 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,11739312 0,14164887 ! negative regulation of cell development GO:0010721 73 25 0,000 0,11739312 0,14157787 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,11739312 0,14150694 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,11739312 0,14143608 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,11739312 0,14136529 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,11739312 0,14129458 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,11739312 0,14122393 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,11739312 0,14115335 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,11739312 0,14108285 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,11739312 0,14101241 ! telomere organization GO:0032200 43 25 0,000 0,11739312 0,14094204 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,11739312 0,14087175 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12179267 0,14607834 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12179267 0,14600556 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12179267 0,14593285 ! initiation of viral infection GO:0019059 57 26 0,000 0,12179267 0,14586021 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12179267 0,14578764 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12179267 0,14571514 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12179267 0,14564272 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,12179267 0,14557037 ! molting cycle process GO:0022404 50 26 0,000 0,12179267 0,14549809 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12179267 0,14542588 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12179267 0,14535375 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12179267 0,14528168 GO:0051297|centrosome organization, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,12179267 0,14520969 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12179267 0,14513777 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12179267 0,14506592 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12179267 0,14499414 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12179267 0,14492243 ! blastocyst development GO:0001824 49 26 0,000 0,12179267 0,14485079 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12179267 0,14477923 ! neuron fate commitment GO:0048663 48 27 0,000 0,12617042 0,14990916 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,12617042 0,14983516 ! iron ion transport GO:0006826 59 27 0,000 0,12617042 0,14976124 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,12617042 0,1496874 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12617042 0,14961362 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12617042 0,14953992 ! fat cell differentiation GO:0045444 50 27 0,000 0,12617042 0,14946629 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12617042 0,14939274 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,12617042 0,14931925 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,12617042 0,14924584 ! autophagy GO:0006914 41 27 0,000 0,12617042 0,1491725 ! male gonad development GO:0008584 44 27 0,000 0,12617042 0,14909923 ! response to toxin GO:0009636 47 27 0,000 0,12617042 0,14902604 ! base-excision repair GO:0006284 41 27 0,000 0,12617042 0,14895291 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12617042 0,14887986 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12617042 0,14880688 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12617042 0,14873397 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12617042 0,14866114 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12617042 0,14858837 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,12617042 0,14851568 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,1305265 0,1535681 ! circadian rhythm GO:0007623 50 28 0,000 0,1305265 0,15349304 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1305265 0,15341806 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,1305265 0,15334315 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,1305265 0,15326831 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1305265 0,15319355 ! synaptogenesis GO:0007416 42 28 0,000 0,1305265 0,15311885 ! lipid oxidation GO:0034440 43 28 0,000 0,1305265 0,15304423 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1305265 0,15296969 ! translational initiation GO:0006413 65 29 0,000 0,13486101 0,15797254 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,13486101 0,15789567 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,13486101 0,15781887 ! regulation of pH GO:0006885 43 29 0,000 0,13486101 0,15774215 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,13486101 0,1576655 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13486101 0,15758892 ! catechol metabolic process GO:0009712 54 29 0,000 0,13486101 0,15751242 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13486101 0,157436 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,13486101 0,15735965 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,13486101 0,15728337 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,13486101 0,15720717 ! cell fate determination GO:0001709 60 29 0,000 0,13486101 0,15713104 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13486101 0,15705498 ! detection of light stimulus GO:0009583 38 29 0,000 0,13486101 0,156979 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,13486101 0,15690309 ! tissue homeostasis GO:0001894 48 29 0,000 0,13486101 0,15682726 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,13917406 0,16176463 ! membrane docking GO:0022406 61 30 0,000 0,13917406 0,16168652 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13917406 0,16160848 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13917406 0,16153052 ! acute-phase response GO:0006953 49 30 0,000 0,13917406 0,16145264 ! myofibril assembly GO:0030239 47 30 0,000 0,13917406 0,16137483 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13917406 0,1612971 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,13917406 0,16121944 ! phospholipid transport GO:0015914 51 30 0,000 0,13917406 0,16114186 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13917406 0,16106435 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13917406 0,16098691 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,13917406 0,16090955 ! eye morphogenesis GO:0048592 60 30 0,000 0,13917406 0,16083227 ! response to heat GO:0009408 50 30 0,000 0,13917406 0,16075505 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14346574 0,16563271 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14346574 0,16555327 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14346574 0,16547391 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14346574 0,16539462 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14346574 0,16531541 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14346574 0,16523627 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,14346574 0,16515721 ! ovulation cycle process GO:0022602 49 31 0,000 0,14346574 0,16507823 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14346574 0,16499932 ! peptide transport GO:0015833 55 31 0,000 0,14346574 0,16492048 ! iron ion homeostasis GO:0055072 54 31 0,000 0,14346574 0,16484172 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14346574 0,16476304 ! natural killer cell activation GO:0030101 45 31 0,000 0,14346574 0,16468443 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14346574 0,1646059 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14346574 0,16452744 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14346574 0,16444906 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,14773617 0,16926344 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,14773617 0,16918288 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,14773617 0,16910239 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,14773617 0,16902198 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,14773617 0,16894165 ! spliceosome assembly GO:0000245 67 32 0,000 0,14773617 0,16886139 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,14773617 0,16878121 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,14773617 0,1687011 ! response to ionizing radiation GO:0010212 65 32 0,000 0,14773617 0,16862107 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,14773617 0,16854112 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,14773617 0,16846124 ! muscle cell development GO:0055001 49 32 0,000 0,14773617 0,16838144 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,14773617 0,16830171 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,14773617 0,16822206 ! ovulation cycle GO:0042698 51 32 0,000 0,14773617 0,16814249 ! gene silencing GO:0016458 65 32 0,000 0,14773617 0,16806299 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,15198545 0,17281521 ! post-embryonic development GO:0009791 69 33 0,000 0,15198545 0,17273358 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,15198545 0,17265202 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15198545 0,17257055 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15198545 0,17248915 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15198545 0,17240782 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,15198545 0,17232657 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15198545 0,1722454 ! adult locomotory behavior GO:0008344 59 33 0,000 0,15198545 0,17216431 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15198545 0,17208329 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,15621368 0,17678745 ! glial cell differentiation GO:0010001 63 34 0,000 0,15621368 0,17670433 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,15621368 0,1766213 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,15621368 0,17653834 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,15621368 0,17645545 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,15621368 0,17637265 ! mismatch repair GO:0006298 46 34 0,000 0,15621368 0,17628992 ! spermatid development GO:0007286 63 34 0,000 0,15621368 0,17620728 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,15621368 0,1761247 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,15621368 0,17604221 ! placenta development GO:0001890 53 34 0,000 0,15621368 0,17595979 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,16042097 0,18061435 ! negative regulation of secretion GO:0051048 63 35 0,000 0,16042097 0,18052987 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,16042097 0,18044547 ! odontogenesis GO:0042476 66 35 0,000 0,16042097 0,18036115 ! female gonad development GO:0008585 58 35 0,000 0,16042097 0,18027691 ! telencephalon development GO:0021537 68 35 0,000 0,16042097 0,18019275 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,16042097 0,18010866 ! cytokine production GO:0001816 59 35 0,000 0,16042097 0,18002466 ! vesicle localization GO:0051648 64 35 0,000 0,16042097 0,17994073 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,16460743 0,18455054 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,16460743 0,18446459 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,16460743 0,18437871 ! positive regulation of cell development GO:0010720 80 36 0,000 0,16460743 0,18429291 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,16460743 0,18420719 ! regulation of proteolysis GO:0030162 72 36 0,000 0,16460743 0,18412156 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,16460743 0,184036 ! aerobic respiration GO:0009060 55 36 0,000 0,16460743 0,18395052 ! embryonic organ development GO:0048568 57 36 0,000 0,16460743 0,18386512 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,16460743 0,1837798 ! RNA export from nucleus GO:0006405 56 37 0,000 0,16877314 0,18834331 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,16877314 0,18825599 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,16877314 0,18816876 ! actomyosin structure organization GO:0031032 62 37 0,000 0,16877314 0,1880816 ! organic anion transport GO:0015711 68 37 0,000 0,16877314 0,18799453 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,16877314 0,18790753 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,16877314 0,18782062 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,16877314 0,18773379 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,16877314 0,18764703 ! spermatid differentiation GO:0048515 66 37 0,000 0,16877314 0,18756036 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,17291822 0,19207814 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,17291822 0,1919895 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,17291822 0,19190094 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,17291822 0,19181247 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,17291822 0,19172407 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,17291822 0,19163576 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,17291822 0,19154753 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,17291822 0,19145938 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,17291822 0,19137132 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,17704277 0,19584593 ! ion transmembrane transport GO:0034220 66 39 0,000 0,17704277 0,19575593 ! RNA modification GO:0009451 57 39 0,000 0,17704277 0,19566601 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,17704277 0,19557617 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18114688 0,20001808 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18114688 0,19992633 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18114688 0,19983467 ! feeding behavior GO:0007631 59 40 0,000 0,18114688 0,19974308 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18114688 0,19965158 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18114688 0,19956017 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,18523067 0,20396567 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,18523067 0,20387236 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,18523067 0,20377914 ! gliogenesis GO:0042063 88 41 0,000 0,18523067 0,20368601 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,18523067 0,20359296 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,18523067 0,20349999 ! female gamete generation GO:0007292 61 41 0,000 0,18523067 0,20340711 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,18523067 0,20331432 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,18929422 0,20767984 ! regulation of tube size GO:0035150 71 42 0,000 0,18929422 0,20758518 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,18929422 0,20749061 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,18929422 0,20739613 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,18929422 0,20730173 ! regulation of protein secretion GO:0050708 71 42 0,000 0,18929422 0,20720741 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,18929422 0,20711319 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,19333764 0,21144107 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,19333764 0,21134501 ! glucose transport GO:0015758 65 43 0,000 0,19333764 0,21124903 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,19333764 0,21115314 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,19333764 0,21105733 ! striated muscle contraction GO:0006941 77 43 0,000 0,19333764 0,21096162 ! phagocytosis GO:0006909 90 43 0,000 0,19333764 0,21086599 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,19333764 0,21077044 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,19736103 0,21505916 ! hexose transport GO:0008645 67 44 0,000 0,19736103 0,21496181 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,19736103 0,21486454 ! male sex differentiation GO:0046661 76 44 0,000 0,19736103 0,21476736 ! double-strand break repair GO:0006302 81 44 0,000 0,19736103 0,21467027 ! biopolymer methylation GO:0043414 84 44 0,000 0,19736103 0,21457326 ! B cell differentiation GO:0030183 107 44 0,000 0,19736103 0,21447635 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,19736103 0,21437952 ! developmental growth GO:0048589 82 44 0,000 0,19736103 0,21428278 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,20136448 0,21853087 ! glycolysis GO:0006096 65 45 0,000 0,20136448 0,21843235 ! leukocyte migration GO:0050900 68 45 0,000 0,20136448 0,21833391 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,20136448 0,21823556 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,20136448 0,2181373 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,20136448 0,21803913 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,20136448 0,21794105 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,20136448 0,21784305 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,20136448 0,21774514 ! cell growth GO:0016049 84 45 0,000 0,20136448 0,21764732 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,2053481 0,2218534 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,2053481 0,22175383 ! pigmentation GO:0043473 100 46 0,000 0,2053481 0,22165434 ! positive regulation of defense response GO:0031349 76 47 0,000 0,20931198 0,22583167 ! response to calcium ion GO:0051592 81 47 0,000 0,20931198 0,22573044 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,20931198 0,22562931 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,20931198 0,22552827 ! JNK cascade GO:0007254 91 47 0,000 0,20931198 0,22542731 ! methylation GO:0032259 90 47 0,000 0,20931198 0,22532645 ! mitochondrial transport GO:0006839 82 48 0,000 0,21325621 0,22946979 ! Notch signaling pathway GO:0007219 96 48 0,000 0,21325621 0,22936721 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,21325621 0,22926472 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,21325621 0,22916233 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,21325621 0,22906002 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,21718091 0,23317147 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,21718091 0,23306747 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,21718091 0,23296356 ! peptide metabolic process GO:0006518 76 49 0,000 0,21718091 0,23285974 ! response to temperature stimulus GO:0009266 76 49 0,000 0,21718091 0,23275602 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,21718091 0,23265239 ! endocrine system development GO:0035270 104 49 0,000 0,21718091 0,23254885 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,21718091 0,2324454 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,21718091 0,23234205 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,21718091 0,23223878 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,21718091 0,23213561 ! neuromuscular process GO:0050905 99 50 0,000 0,22108615 0,23620483 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,22108615 0,23609999 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,22108615 0,23599524 ! viral infectious cycle GO:0019058 99 51 0,000 0,22497204 0,24003669 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,22497204 0,23993029 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,22497204 0,23982398 ! excretion GO:0007588 83 51 0,000 0,22497204 0,23971777 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,22497204 0,23961166 ! chromatin remodeling GO:0006338 109 51 0,000 0,22497204 0,23950563 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,22497204 0,2393997 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,22497204 0,23929387 ! regulation of cell shape GO:0008360 125 51 0,000 0,22497204 0,23918813 ! membrane fusion GO:0006944 110 52 0,000 0,22883867 0,24319163 ! amino acid activation GO:0043038 92 52 0,000 0,22883867 0,24308426 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,22883867 0,24297699 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,23268614 0,24695318 ! regulation of translational initiation GO:0006446 82 53 0,000 0,23268614 0,2468443 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,23268614 0,24673551 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,23268614 0,24662681 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,23268614 0,24651821 ! cell maturation GO:0048469 100 53 0,000 0,23268614 0,24640971 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,23268614 0,2463013 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,23651455 0,25024362 ! cell recognition GO:0008037 85 54 0,000 0,23651455 0,25013363 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,23651455 0,25002372 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,23651455 0,24991392 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,23651455 0,24980421 ! chloride transport GO:0006821 90 55 0,000 0,24032397 0,25371631 ! glucose catabolic process GO:0006007 82 55 0,000 0,24032397 0,25360504 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,24032397 0,25349385 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,24032397 0,25338277 ! RNA elongation GO:0006354 79 55 0,000 0,24032397 0,25327178 ! regulation of actin filament length GO:0030832 105 56 0,000 0,24411452 0,25715391 ! sensory perception of smell GO:0007608 80 56 0,000 0,24411452 0,25704137 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,24411452 0,25692893 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,24411452 0,25681659 ! proton transport GO:0015992 94 56 0,000 0,24411452 0,25670434 ! hydrogen transport GO:0006818 97 58 0,000 0,25163934 0,26450164 ! regulation of endocytosis GO:0030100 91 58 0,000 0,25163934 0,26438614 ! adult behavior GO:0030534 99 58 0,000 0,25163934 0,26427073 ! positive regulation of secretion GO:0051047 95 59 0,000 0,2553738 0,26807564 ! regulation of cellular component size GO:0032535 109 59 0,000 0,2553738 0,26795873 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,2553738 0,26784192 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,2553738 0,26772521 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,25908975 0,27150258 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,25908975 0,27138438 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,25908975 0,27126629 ! regulation of heart contraction GO:0008016 110 60 0,000 0,25908975 0,27114829 ! camera-type eye development GO:0043010 116 60 0,000 0,25908975 0,2710304 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,26278727 0,27477887 ! tRNA processing GO:0008033 89 61 0,000 0,26278727 0,2746595 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,26278727 0,27454024 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,26646647 0,27826316 ! gonad development GO:0008406 98 62 0,000 0,26646647 0,27814244 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,27012742 0,28184154 ! detection of external stimulus GO:0009581 91 63 0,000 0,27012742 0,28171937 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,27012742 0,28159731 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,27377023 0,28527119 ! cell redox homeostasis GO:0045454 102 64 0,000 0,27377023 0,28514769 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,27377023 0,28502431 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,27377023 0,28490103 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,27377023 0,28477785 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,27739497 0,28842364 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,27739497 0,28829905 ! germ cell development GO:0007281 118 65 0,000 0,27739497 0,28817457 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,27739497 0,2880502 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,28100175 0,29166963 ! extracellular matrix organization GO:0030198 133 66 0,000 0,28100175 0,29154386 ! secondary metabolic process GO:0019748 116 66 0,000 0,28100175 0,29141819 ! developmental maturation GO:0021700 116 66 0,000 0,28100175 0,29129264 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,28459064 0,29488591 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,28459064 0,29475897 ! hexose catabolic process GO:0019320 104 67 0,000 0,28459064 0,29463213 ! adaptive immune response GO:0002250 119 67 0,000 0,28459064 0,29450541 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 0,000 0,28816173 0,29807271 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,28816173 0,29794462 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,28816173 0,29781664 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,29171512 0,30135963 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,29171512 0,30123029 ! antigen processing and presentation GO:0019882 104 69 0,000 0,29171512 0,30110106 ! amine catabolic process GO:0009310 117 71 0,000 0,29876912 0,30824979 ! reproductive structure development GO:0048608 113 71 0,000 0,29876912 0,30811766 ! B cell activation GO:0042113 160 71 0,000 0,29876912 0,30798565 ! acute inflammatory response GO:0002526 113 72 0,000 0,30226991 0,31146098 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,30226991 0,31132765 ! carbohydrate transport GO:0008643 110 72 0,000 0,30226991 0,31119444 ! regulation of blood pressure GO:0008217 125 73 0,000 0,30575333 0,31464607 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,30575333 0,31451155 ! fertilization GO:0009566 90 73 0,000 0,30575333 0,31437715 ! neurotransmitter transport GO:0006836 123 74 0,000 0,30921948 0,31780524 ! exocytosis GO:0006887 133 74 0,000 0,30921948 0,31766955 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,30921948 0,31753396 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,30921948 0,3173985 ! eye development GO:0001654 143 74 0,000 0,30921948 0,31726315 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,31266844 0,32066508 ! rhythmic process GO:0048511 128 75 0,000 0,31266844 0,32052845 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,3161003 0,32390857 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,3161003 0,32377067 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,3161003 0,3236329 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,31951513 0,32698996 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,31951513 0,32685093 ! blood coagulation GO:0007596 146 78 0,000 0,32291302 0,33018645 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,32291302 0,33004619 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,32291302 0,32990604 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,32629406 0,33321881 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,32629406 0,33307743 ! response to metal ion GO:0010038 140 80 0,000 0,32965833 0,33636893 ! muscle cell differentiation GO:0042692 159 80 0,000 0,32965833 0,33622634 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,32965833 0,33608387 ! protein import into nucleus GO:0006606 158 80 0,000 0,32965833 0,33594152 ! inorganic anion transport GO:0015698 138 80 0,000 0,32965833 0,3357993 ! digestion GO:0007586 112 81 0,000 0,33300591 0,33906569 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,33300591 0,33892226 ! nuclear import GO:0051170 161 81 0,000 0,33300591 0,33877895 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,33633688 0,34202305 ! response to drug GO:0042493 143 82 0,000 0,33633688 0,34187855 ! response to nutrient GO:0007584 125 82 0,000 0,33633688 0,34173418 ! hemostasis GO:0007599 158 84 0,000 0,34294934 0,34830566 ! response to unfolded protein GO:0006986 131 85 0,000 0,34623098 0,35149018 ! nucleosome assembly GO:0006334 122 85 0,000 0,34623098 0,35134194 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,34623098 0,35119382 ! amine biosynthetic process GO:0009309 138 86 0,000 0,34949634 0,35435659 ! response to inorganic substance GO:0010035 153 86 0,000 0,34949634 0,35420733 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,34949634 0,35405819 ! chromatin assembly GO:0031497 124 86 0,000 0,34949634 0,35390917 ! alcohol catabolic process GO:0046164 130 86 0,000 0,34949634 0,35376029 ! amine transport GO:0015837 155 86 0,000 0,34949634 0,35361152 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,3527455 0,35674892 ! protein localization in nucleus GO:0034504 176 87 0,000 0,3527455 0,35659902 ! cellular respiration GO:0045333 135 88 0,000 0,35597854 0,35971624 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,35597854 0,35956523 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,35597854 0,35941434 ! cellular defense response GO:0006968 114 89 0,000 0,35919554 0,36251026 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,35919554 0,36235827 ! sex differentiation GO:0007548 145 90 0,000 0,36239657 0,36543427 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,36239657 0,36528117 ! sterol metabolic process GO:0016125 152 91 0,000 0,36558172 0,36833737 ! response to protein stimulus GO:0051789 149 91 0,000 0,36558172 0,36818319 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,36558172 0,36802913 ! regulation of defense response GO:0031347 149 92 0,000 0,36875107 0,37106444 ! nucleosome organization GO:0034728 138 92 0,000 0,36875107 0,37090931 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,36875107 0,37075431 ! vitamin metabolic process GO:0006766 139 92 0,000 0,36875107 0,37059945 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,37190469 0,37361281 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,37504265 0,37660794 ! female pregnancy GO:0007565 164 94 0,000 0,37504265 0,37645082 ! transcription initiation GO:0006352 153 94 0,000 0,37504265 0,37629384 ! forebrain development GO:0030900 188 95 0,000 0,37816504 0,37926849 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,38127194 0,38222512 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! detection of stimulus GO:0051606 151 96 0,000 0,38127194 0,38206593 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,38436342 0,38500349 ! hormone metabolic process GO:0042445 157 97 0,000 0,38436342 0,38484327 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,38743955 0,38776188 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,38743955 0,38760065 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,39050041 0,39050041