pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6261-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of cell-matrix adhesion GO:0001953 37 11 4,000 9,445E-10 2,307E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of protein kinase activity GO:0006469 144 69 7,000 1,254E-09 1,531E-06 ! negative regulation of kinase activity GO:0033673 145 70 7,000 1,41E-09 1,148E-06 ! negative regulation of transferase activity GO:0051348 155 74 7,000 2,215E-09 1,353E-06 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 2,286E-09 1,117E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 6,832E-09 2,782E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 6,000 9,271E-09 3,236E-06 ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 1,588E-08 4,85E-06 ! regulation of protein stability GO:0031647 77 38 5,000 2,311E-08 6,274E-06 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 3,165E-08 7,732E-06 ! regulation of cell-matrix adhesion GO:0001952 81 23 4,000 6,574E-08 1,46E-05 GO:0010810|regulation of cell-substrate adhesion, ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 9,426E-08 1,919E-05 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 3,000 1,476E-07 2,773E-05 ! regulation of B cell proliferation GO:0030888 22 12 3,000 2,206E-07 3,849E-05 ! negative regulation of protein kinase cascade GO:0010741 72 30 4,000 2,712E-07 4,416E-05 ! protein amino acid autophosphorylation GO:0046777 157 64 5,000 5,678E-07 8,67E-05 ! negative regulation of cell adhesion GO:0007162 94 37 4,000 8,078E-07 1,161E-04 ! endothelial cell migration GO:0043542 31 17 3,000 1,041E-06 1,413E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 3,000 1,041E-06 1,339E-04 ! cardiac muscle tissue development GO:0048738 34 17 3,000 1,041E-06 1,272E-04 ! inositol metabolic process GO:0006020 33 19 3,000 1,684E-06 1,959E-04 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 2,000 1,98E-06 2,199E-04 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 2,456E-06 2,608E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 2,581E-06 2,627E-04 ! regulation of mast cell proliferation GO:0070666 89 49 4,000 3,378E-06 3,301E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 4,532E-06 4,259E-04 ! regulation of cell adhesion GO:0030155 241 92 5,000 4,849E-06 4,387E-04 ! regulation of leukocyte proliferation GO:0070663 97 53 4,000 5,007E-06 4,369E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of MAP kinase activity GO:0043406 174 93 5,000 5,163E-06 4,35E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 5,507E-06 4,484E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 5,507E-06 4,34E-04 ! negative regulation of cell motion GO:0051271 142 55 4,000 6,024E-06 4,599E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 6,33E-06 4,686E-04 GO:0045936|negative regulation of phosphate metabolic process, ! receptor clustering GO:0043113 20 9 2,000 8,232E-06 5,915E-04 ! dendrite development GO:0016358 67 28 3,000 8,607E-06 6,007E-04 ! lipid modification GO:0030258 112 60 4,000 9,281E-06 6,298E-04 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 3,000 1,144E-05 7,551E-04 ! regulation of B cell activation GO:0050864 55 30 3,000 1,144E-05 7,352E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,172E-05 7,341E-04 ! positive regulation of B cell proliferation GO:0030890 18 10 2,000 1,172E-05 7,157E-04 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 3,000 1,907E-05 1,136E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,134E-05 1,241E-03 GO:0042130|negative regulation of T cell proliferation, ! learning or memory GO:0007611 161 76 4,000 2,956E-05 1,68E-03 ! phosphoinositide metabolic process GO:0030384 146 77 4,000 3,15E-05 1,749E-03 ! mRNA catabolic process GO:0006402 79 41 3,000 4,06E-05 2,204E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 2,000 4,368E-05 2,32E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 4,368E-05 2,27E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 4,471E-05 2,276E-03 ! regulation of T cell differentiation GO:0045580 78 42 3,000 4,471E-05 2,229E-03 ! regulation of T cell proliferation GO:0042129 80 43 3,000 4,912E-05 2,4E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 5,357E-05 2,566E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! polyol metabolic process GO:0019751 77 45 3,000 5,887E-05 2,766E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 6,425E-05 2,961E-03 ! negative regulation of cell migration GO:0030336 122 46 3,000 6,425E-05 2,907E-03 ! signal complex assembly GO:0007172 47 17 2,000 6,483E-05 2,88E-03 ! regulation of cell cycle process GO:0010564 161 90 4,000 6,672E-05 2,911E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 7,753E-05 3,323E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 7,753E-05 3,265E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 8,251E-05 3,417E-03 ! neuromuscular junction development GO:0007528 43 19 2,000 9,175E-05 3,736E-03 ! negative regulation of immune system process GO:0002683 101 51 3,000 9,662E-05 3,869E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 1E-04 3,942E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,076E-04 4,171E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,076E-04 4,106E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 1,101E-04 4,138E-03 GO:0060538|skeletal muscle organ development, ! RNA catabolic process GO:0006401 103 55 3,000 1,3E-04 4,81E-03 ! response to UV GO:0009411 120 55 3,000 1,3E-04 4,739E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 1,443E-04 5,185E-03 ! positive regulation of B cell activation GO:0050871 42 22 2,000 1,443E-04 5,11E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 1,494E-04 5,215E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,884E-04 6,482E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 1,884E-04 6,392E-03 ! leukocyte adhesion GO:0007159 55 25 2,000 2,133E-04 7,139E-03 ! receptor metabolic process GO:0043112 53 25 2,000 2,133E-04 7,043E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,148E-04 6,997E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 1,000 2,148E-04 6,905E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,148E-04 6,815E-03 ! microvillus organization GO:0032528 8 5 1,000 2,148E-04 6,728E-03 GO:0030033|microvillus assembly, ! positive regulation of filopodium assembly GO:0051491 16 5 1,000 2,148E-04 6,643E-03 GO:0051489|regulation of filopodium assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,148E-04 6,56E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 2,148E-04 6,479E-03 ! cellular glucose homeostasis GO:0001678 6 5 1,000 2,148E-04 6,4E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,148E-04 6,323E-03 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 2,148E-04 6,247E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 1,000 2,148E-04 6,174E-03 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 1,000 2,148E-04 6,102E-03 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 1,000 2,148E-04 6,032E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 1,000 2,148E-04 5,963E-03 ! stem cell division GO:0017145 11 5 1,000 2,148E-04 5,896E-03 GO:0048103|somatic stem cell division, ! insulin receptor signaling pathway GO:0008286 66 27 2,000 2,694E-04 7,314E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 2,694E-04 7,234E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 3,007E-04 7,986E-03 ! thymic T cell selection GO:0045061 16 6 1,000 3,212E-04 8,438E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 1,000 3,212E-04 8,349E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 3,212E-04 8,261E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 3,212E-04 8,175E-03 GO:0051653|spindle localization, ! negative regulation of B cell activation GO:0050869 14 6 1,000 3,212E-04 8,09E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 3,343E-04 8,334E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 3,000 3,686E-04 9,096E-03 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 3,702E-04 9,043E-03 GO:0043433|negative regulation of transcription factor activity, ! cell junction assembly GO:0034329 85 31 2,000 4,084E-04 9,879E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,084E-04 9,782E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 4,084E-04 9,687E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 4,084E-04 9,594E-03 ! regulation of transcription factor activity GO:0051090 137 75 3,000 4,308E-04 0,01002253 GO:0090046|regulation of transcription regulator activity, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,483E-04 0,01033293 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,483E-04 0,01023636 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,483E-04 0,01014158 ! positive regulation of isotype switching GO:0045830 17 7 1,000 4,483E-04 0,01004853 GO:0045911|positive regulation of DNA recombination, ! male sex determination GO:0030238 15 7 1,000 4,483E-04 9,957E-03 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 4,483E-04 9,867E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 1,000 4,483E-04 9,779E-03 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 4,483E-04 9,693E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 4,483E-04 9,608E-03 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 4,491E-04 9,541E-03 ! mesoderm formation GO:0001707 73 32 2,000 4,491E-04 9,459E-03 ! negative regulation of protein transport GO:0051224 74 33 2,000 4,924E-04 0,01028087 ! formation of primary germ layer GO:0001704 76 34 2,000 5,382E-04 0,01114202 ! regulation of synaptic plasticity GO:0048167 78 35 2,000 5,866E-04 0,01204288 ! mesoderm morphogenesis GO:0048332 80 35 2,000 5,866E-04 0,01194252 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 5,959E-04 0,01203225 ! ER overload response GO:0006983 13 8 1,000 5,959E-04 0,01193363 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,959E-04 0,01183661 ! synaptic transmission, glutamatergic GO:0035249 24 8 1,000 5,959E-04 0,01174115 ! gas homeostasis GO:0033483 14 8 1,000 5,959E-04 0,01164722 ! dendrite morphogenesis GO:0048813 14 8 1,000 5,959E-04 0,01155478 ! regulation of respiratory burst GO:0060263 12 8 1,000 5,959E-04 0,0114638 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 5,959E-04 0,01137424 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 5,959E-04 0,01128607 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 5,959E-04 0,01119925 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 5,959E-04 0,01111376 ! regulation of peptidase activity GO:0052547 150 82 3,000 6,044E-04 0,01118574 ! negative regulation of DNA binding GO:0043392 67 36 2,000 6,378E-04 0,01171461 ! cell junction organization GO:0034330 96 37 2,000 6,917E-04 0,0126099 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 6,917E-04 0,01251649 ! regulation of microtubule-based process GO:0032886 86 37 2,000 6,917E-04 0,01242446 ! negative regulation of cell activation GO:0050866 69 37 2,000 6,917E-04 0,01233377 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 7,484E-04 0,01324852 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 7,484E-04 0,0131532 ! regulation of protein transport GO:0051223 165 87 3,000 7,554E-04 0,01318144 GO:0070201|regulation of establishment of protein localization, ! axon extension GO:0048675 16 9 1,000 7,639E-04 0,01323496 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,639E-04 0,01314176 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 7,639E-04 0,01304986 ! regulation of glycolysis GO:0006110 20 9 1,000 7,639E-04 0,01295923 ! microtubule bundle formation GO:0001578 22 9 1,000 7,639E-04 0,01286986 ! middle ear morphogenesis GO:0042474 14 9 1,000 7,639E-04 0,01278171 ! T cell selection GO:0045058 27 9 1,000 7,639E-04 0,01269476 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 7,639E-04 0,01260898 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 1,000 7,639E-04 0,01252436 ! postreplication repair GO:0006301 25 9 1,000 7,639E-04 0,01244086 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 7,639E-04 0,01235847 GO:0002820|negative regulation of adaptive immune response, ! negative regulation of binding GO:0051100 71 39 2,000 8,08E-04 0,01298612 ! carbohydrate homeostasis GO:0033500 59 39 2,000 8,08E-04 0,01290125 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 8,08E-04 0,01281747 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of DNA binding GO:0051101 167 89 3,000 8,226E-04 0,01296571 ! mammary gland development GO:0030879 93 40 2,000 8,705E-04 0,01363238 ! Rho protein signal transduction GO:0007266 88 40 2,000 8,705E-04 0,01354555 ! mesenchymal cell development GO:0014031 94 41 2,000 9,36E-04 0,01447288 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of developmental growth GO:0048638 16 10 1,000 9,519E-04 0,01462581 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 9,519E-04 0,0145344 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 9,519E-04 0,01444413 ! central nervous system neuron axonogenesis GO:0021955 23 10 1,000 9,519E-04 0,01435496 GO:0021952|central nervous system projection neuron axonogenesis, ! motor axon guidance GO:0008045 22 10 1,000 9,519E-04 0,0142669 ! protein heterooligomerization GO:0051291 17 10 1,000 9,519E-04 0,0141799 ! regulation of B cell differentiation GO:0045577 24 10 1,000 9,519E-04 0,01409397 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 9,519E-04 0,01400906 ! midbrain development GO:0030901 14 10 1,000 9,519E-04 0,01392518 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 9,519E-04 0,01384229 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 23 10 1,000 9,519E-04 0,01376038 ! T cell differentiation GO:0030217 93 42 2,000 1,005E-03 0,01443655 ! neuron migration GO:0001764 85 43 2,000 1,076E-03 0,0153759 ! regulation of T cell activation GO:0050863 175 96 3,000 1,091E-03 0,01550034 ! regulation of protein localization GO:0032880 188 97 3,000 1,134E-03 0,01601568 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,16E-03 0,01628486 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,16E-03 0,0161918 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,16E-03 0,0160998 ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 1,16E-03 0,01600884 ! regulation of isotype switching GO:0045191 24 11 1,000 1,16E-03 0,01591891 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,16E-03 0,01582997 ! regulation of embryonic development GO:0045995 35 11 1,000 1,16E-03 0,01574203 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,229E-03 0,01658911 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,31E-03 0,01758881 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,388E-03 0,01852379 ! virus-host interaction GO:0019048 30 12 1,000 1,388E-03 0,01842311 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,388E-03 0,01832353 ! regulation of cell projection assembly GO:0060491 33 12 1,000 1,388E-03 0,01822502 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,388E-03 0,01812756 ! T cell proliferation GO:0042098 32 12 1,000 1,388E-03 0,01803113 ! focal adhesion formation GO:0048041 37 12 1,000 1,388E-03 0,01793573 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 1,000 1,388E-03 0,01784133 ! histone acetylation GO:0016573 27 12 1,000 1,388E-03 0,01774792 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,388E-03 0,01765548 ! localization within membrane GO:0051668 26 12 1,000 1,388E-03 0,017564 ! response to insulin stimulus GO:0032868 98 47 2,000 1,395E-03 0,01756583 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,483E-03 0,01857727 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,635E-03 0,0203771 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,635E-03 0,02027366 ! gland morphogenesis GO:0022612 31 13 1,000 1,635E-03 0,02017127 ! positive regulation of homeostatic process GO:0032846 23 13 1,000 1,635E-03 0,02006991 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 1,000 1,635E-03 0,01996956 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 1,635E-03 0,0198702 ! activation of caspase activity GO:0006919 95 50 2,000 1,669E-03 0,02018421 ! regulation of S phase GO:0033261 26 14 1,000 1,901E-03 0,02288319 ! lipid localization GO:0010876 32 14 1,000 1,901E-03 0,02277101 GO:0019915|lipid storage, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 1,901E-03 0,02265994 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 1,901E-03 0,02254994 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 1,901E-03 0,022441 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 1,901E-03 0,02233311 ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 1,901E-03 0,02222625 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 1,901E-03 0,02212041 ! synapse organization GO:0050808 102 53 2,000 1,974E-03 0,02286016 ! activation of phospholipase C activity GO:0007202 110 54 2,000 2,083E-03 0,02400872 GO:0010863|positive regulation of phospholipase C activity, ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,083E-03 0,023896 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,187E-03 0,02496977 ! regulation of vasodilation GO:0042312 27 15 1,000 2,187E-03 0,02485363 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 2,187E-03 0,02473857 ! positive regulation of calcium ion transport GO:0051928 21 15 1,000 2,187E-03 0,02462457 ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 2,196E-03 0,0246109 ! skeletal muscle fiber development GO:0048741 130 56 2,000 2,313E-03 0,02579718 ! positive regulation of caspase activity GO:0043280 108 57 2,000 2,433E-03 0,0270144 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 2,433E-03 0,02689216 ! regulation of phospholipase activity GO:0010517 113 57 2,000 2,433E-03 0,02677102 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,492E-03 0,02730133 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 2,492E-03 0,02717945 ! heterophilic cell adhesion GO:0007157 43 16 1,000 2,492E-03 0,02705865 ! positive regulation of ion transport GO:0043270 23 16 1,000 2,492E-03 0,02693892 ! negative regulation of immune response GO:0050777 38 16 1,000 2,492E-03 0,02682025 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,492E-03 0,02670261 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 1,000 2,492E-03 0,02658601 ! positive regulation of cell migration GO:0030335 137 58 2,000 2,557E-03 0,02715665 ! gastrulation GO:0007369 122 58 2,000 2,557E-03 0,02703909 ! positive regulation of organelle organization GO:0010638 108 58 2,000 2,557E-03 0,02692254 ! positive regulation of lipase activity GO:0060193 115 58 2,000 2,557E-03 0,026807 ! positive regulation of cell killing GO:0031343 36 17 1,000 2,816E-03 0,02939675 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,816E-03 0,02927166 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 2,816E-03 0,02914762 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 2,816E-03 0,02902464 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,816E-03 0,02890268 GO:0031114|regulation of microtubule depolymerization, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 2,816E-03 0,02878175 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 1,000 2,816E-03 0,02866183 GO:0002712|regulation of B cell mediated immunity, ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 2,816E-03 0,0285429 ! regulation of homeostatic process GO:0032844 148 62 2,000 3,091E-03 0,03120737 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 3,158E-03 0,03174905 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 3,158E-03 0,03161893 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 3,158E-03 0,03148987 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 3,158E-03 0,03136187 ! defense response to virus GO:0051607 43 18 1,000 3,158E-03 0,0312349 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,158E-03 0,03110895 ! mesoderm development GO:0007498 128 63 2,000 3,235E-03 0,0317384 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 3,382E-03 0,03305349 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 3,519E-03 0,0342482 ! memory GO:0007613 34 19 1,000 3,519E-03 0,0341123 ! protein export from nucleus GO:0006611 40 19 1,000 3,519E-03 0,03397747 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 3,519E-03 0,0338437 ! positive regulation of cell motion GO:0051272 157 65 2,000 3,534E-03 0,03385805 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 3,69E-03 0,03521186 ! negative regulation of cell growth GO:0030308 142 67 2,000 3,85E-03 0,03659438 ! activation of MAPK activity GO:0000187 124 67 2,000 3,85E-03 0,03645254 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 3,898E-03 0,03676542 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,898E-03 0,03662402 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,898E-03 0,0364837 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 3,898E-03 0,03634445 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 3,898E-03 0,03620625 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 3,898E-03 0,03606911 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,898E-03 0,035933 ! actin filament bundle formation GO:0051017 47 20 1,000 3,898E-03 0,03579791 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 3,898E-03 0,03566384 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 3,898E-03 0,03553076 ! negative regulation of ligase activity GO:0051352 116 68 2,000 4,014E-03 0,03645146 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 137 68 2,000 4,014E-03 0,03631645 ! negative regulation of cell size GO:0045792 144 69 2,000 4,182E-03 0,0376988 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 4,182E-03 0,0375602 ! regulation of cell killing GO:0031341 46 21 1,000 4,295E-03 0,03843379 ! lipid phosphorylation GO:0046834 43 21 1,000 4,295E-03 0,03829352 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 4,295E-03 0,03815427 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 4,295E-03 0,03801603 ! regulation of vasoconstriction GO:0019229 40 21 1,000 4,295E-03 0,03787879 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 4,295E-03 0,03774254 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 4,295E-03 0,03760726 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 4,531E-03 0,03953314 ! hindlimb morphogenesis GO:0035137 47 22 1,000 4,71E-03 0,04094808 ! glutamate signaling pathway GO:0007215 48 22 1,000 4,71E-03 0,04080288 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,71E-03 0,0406587 ! cellular response to starvation GO:0009267 37 22 1,000 4,71E-03 0,04051553 ! central nervous system neuron development GO:0021954 47 22 1,000 4,71E-03 0,04037337 ! apoptotic nuclear changes GO:0030262 34 22 1,000 4,71E-03 0,04023221 ! ureteric bud development GO:0001657 50 22 1,000 4,71E-03 0,04009202 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 4,71E-03 0,03995282 ! peptidyl-serine modification GO:0018209 50 22 1,000 4,71E-03 0,03981457 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 4,71E-03 0,03967728 ! protein stabilization GO:0050821 41 22 1,000 4,71E-03 0,03954093 ! actin filament organization GO:0007015 167 72 2,000 4,712E-03 0,03942261 ! regulation of caspase activity GO:0043281 136 74 2,000 5,087E-03 0,04241414 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,143E-03 0,04273394 ! regulation of DNA recombination GO:0000018 51 23 1,000 5,143E-03 0,04258908 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 5,143E-03 0,04244519 ! nerve-nerve synaptic transmission GO:0007270 59 23 1,000 5,143E-03 0,04230228 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 5,281E-03 0,04329295 ! lymphocyte differentiation GO:0030098 193 76 2,000 5,479E-03 0,04476924 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,593E-03 0,04554701 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 5,593E-03 0,04539569 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 5,593E-03 0,04524537 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 5,593E-03 0,04509605 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 1,000 5,593E-03 0,04494771 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 5,593E-03 0,04480034 ! sex determination GO:0007530 48 24 1,000 5,593E-03 0,04465393 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 5,593E-03 0,04450848 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 45 24 1,000 5,593E-03 0,04436397 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 5,593E-03 0,0442204 ! negative regulation of catabolic process GO:0009895 52 24 1,000 5,593E-03 0,04407775 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 5,682E-03 0,04463512 ! regulation of catabolic process GO:0009894 173 77 2,000 5,682E-03 0,04449205 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 5,889E-03 0,04596778 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 6,061E-03 0,04715594 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 6,061E-03 0,04700624 ! vasculogenesis GO:0001570 49 25 1,000 6,061E-03 0,04685749 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 6,061E-03 0,04670967 ! interaction with host GO:0051701 66 25 1,000 6,061E-03 0,04656279 ! lymphocyte proliferation GO:0046651 55 25 1,000 6,061E-03 0,04641682 ! immunoglobulin production GO:0002377 62 25 1,000 6,061E-03 0,04627177 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 6,061E-03 0,04612762 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 6,101E-03 0,04628958 ! protein oligomerization GO:0051259 149 79 2,000 6,101E-03 0,04614627 ! regulation of synaptic transmission GO:0050804 159 79 2,000 6,101E-03 0,04600384 ! negative regulation of organelle organization GO:0010639 181 80 2,000 6,317E-03 0,04748792 ! response to hypoxia GO:0001666 178 81 2,000 6,538E-03 0,0489968 ! myelination GO:0042552 50 26 1,000 6,546E-03 0,04890506 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 6,546E-03 0,04875596 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 6,546E-03 0,04860776 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 6,546E-03 0,04846046 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 6,546E-03 0,04831406 ! osteoblast differentiation GO:0001649 63 26 1,000 6,546E-03 0,04816853 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 6,546E-03 0,04802388 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 6,546E-03 0,0478801 ! regulation of blood coagulation GO:0030193 46 26 1,000 6,546E-03 0,04773717 ! positive regulation of nuclear division GO:0051785 41 26 1,000 6,546E-03 0,0475951 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 6,546E-03 0,04745387 ! neural tube closure GO:0001843 58 26 1,000 6,546E-03 0,04731347 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 6,546E-03 0,0471739 ! response to oxygen levels GO:0070482 183 83 2,000 6,994E-03 0,05025036 ! embryonic pattern specification GO:0009880 49 27 1,000 7,048E-03 0,05049457 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 7,048E-03 0,05034693 ! tube lumen formation GO:0035148 59 27 1,000 7,048E-03 0,05020014 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 7,048E-03 0,05005421 ! response to starvation GO:0042594 47 27 1,000 7,048E-03 0,04990913 ! regulation of chromosome organization GO:0033044 49 27 1,000 7,048E-03 0,04976488 ! cellular response to nutrient levels GO:0031669 45 27 1,000 7,048E-03 0,04962147 ! leukocyte proliferation GO:0070661 59 27 1,000 7,048E-03 0,04947888 GO:0032943|mononuclear cell proliferation, ! T cell activation GO:0042110 189 84 2,000 7,228E-03 0,05059602 ! regulation of ligase activity GO:0051340 147 84 2,000 7,228E-03 0,05045146 ! negative regulation of transport GO:0051051 164 85 2,000 7,467E-03 0,05197201 ! negative regulation of growth GO:0045926 168 85 2,000 7,467E-03 0,05182436 ! regulation of neuron differentiation GO:0045664 187 85 2,000 7,467E-03 0,05167755 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 7,467E-03 0,05153157 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 7,467E-03 0,05138641 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 7,567E-03 0,05192877 ! protein amino acid acylation GO:0043543 59 28 1,000 7,567E-03 0,05178331 ! negative regulation of protein modification process GO:0031400 66 28 1,000 7,567E-03 0,05163867 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 7,567E-03 0,05149483 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 7,567E-03 0,05135179 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 7,567E-03 0,05120954 ! positive regulation of cell activation GO:0050867 161 86 2,000 7,711E-03 0,05203775 GO:0002696|positive regulation of leukocyte activation, ! primary neural tube formation GO:0014020 61 29 1,000 8,103E-03 0,05453314 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 8,103E-03 0,05438332 ! somitogenesis GO:0001756 52 29 1,000 8,103E-03 0,05423432 ! tube morphogenesis GO:0035239 194 89 2,000 8,47E-03 0,05653711 ! regulation of neurological system process GO:0031644 175 89 2,000 8,47E-03 0,05638306 ! immune response-activating signal transduction GO:0002757 58 30 1,000 8,655E-03 0,05745896 GO:0002764|immune response-regulating signal transduction, ! regulation of coagulation GO:0050818 52 30 1,000 8,655E-03 0,05730325 ! ossification GO:0001503 205 91 2,000 9E-03 0,0594235 ! gland development GO:0048732 220 91 2,000 9E-03 0,05926333 ! zinc ion transport GO:0006829 54 31 1,000 9,224E-03 0,06057622 ! ensheathment of neurons GO:0007272 64 31 1,000 9,224E-03 0,06041382 GO:0008366|axon ensheathment, ! positive regulation of immune effector process GO:0002699 78 31 1,000 9,224E-03 0,06025228 ! bone development GO:0060348 206 92 2,000 9,272E-03 0,06040302 ! spindle organization GO:0007051 50 32 1,000 9,809E-03 0,06373269 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 9,809E-03 0,06356364 ! metanephros development GO:0001656 81 32 1,000 9,809E-03 0,06339548 ! peripheral nervous system development GO:0007422 68 32 1,000 9,809E-03 0,06322821 ! BMP signaling pathway GO:0030509 71 32 1,000 9,809E-03 0,06306182 ! hindbrain development GO:0030902 65 32 1,000 9,809E-03 0,06289631 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 9,809E-03 0,06273166 ! positive regulation of catabolic process GO:0009896 72 32 1,000 9,809E-03 0,06256787 ! regulation of membrane potential GO:0042391 179 94 2,000 9,83E-03 0,06253899 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,01041012 0,06605694 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 0,01041012 0,06588581 ! regulation of calcium ion transport GO:0051924 60 33 1,000 0,01041012 0,06571556 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,01070353 0,06739362 ! leukocyte differentiation GO:0002521 232 98 2,000 0,01100433 0,06910946 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,01102712 0,06907498 ! cholesterol transport GO:0030301 62 34 1,000 0,01102712 0,06889832 ! cell fate specification GO:0001708 56 34 1,000 0,01102712 0,06872256 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01102712 0,06854769 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01102712 0,06837371 ! mRNA transport GO:0051028 185 100 2,000 0,01162051 0,07187065 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01165987 0,071932 ! sterol transport GO:0015918 63 35 1,000 0,01165987 0,07175081 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01165987 0,07157053 ! regulation of muscle development GO:0048634 82 36 1,000 0,01230823 0,07536093 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01230823 0,07517253 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01297204 0,07902914 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! sister chromatid segregation GO:0000819 65 37 1,000 0,01297204 0,07883255 ! tissue remodeling GO:0048771 78 37 1,000 0,01297204 0,07863694 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01297204 0,07844229 ! meiosis I GO:0007127 74 38 1,000 0,01365113 0,08234496 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01365113 0,08214214 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,01365113 0,08194032 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01365113 0,08173948 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01365113 0,08153963 ! neural tube formation GO:0001841 79 38 1,000 0,01365113 0,08134075 ! regulation of metal ion transport GO:0010959 71 39 1,000 0,01434535 0,08526934 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,01434535 0,08506237 ! glucan metabolic process GO:0044042 64 39 1,000 0,01434535 0,08485641 GO:0006073|cellular glucan metabolic process, ! lipid homeostasis GO:0055088 75 40 1,000 0,01505456 0,08883642 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01505456 0,08862236 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,01505456 0,08840933 ! learning GO:0007612 82 40 1,000 0,01505456 0,08819731 ! nucleus organization GO:0006997 73 40 1,000 0,01505456 0,08798632 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,01577858 0,0919978 ! maintenance of protein location GO:0045185 95 41 1,000 0,01577858 0,09177876 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01577858 0,09156076 ! ear morphogenesis GO:0042471 64 42 1,000 0,01651728 0,09562019 ! organic ether metabolic process GO:0018904 59 42 1,000 0,01651728 0,09539414 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 0,01651728 0,09516915 ! cytokinesis GO:0000910 84 42 1,000 0,01651728 0,09494523 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,0172705 0,09904188 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,0172705 0,09880993 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,0172705 0,09857907 ! segmentation GO:0035282 78 43 1,000 0,0172705 0,09834928 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,0180381 0,10248156 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,0180381 0,10224378 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,01881991 0,10642834 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,01881991 0,10618255 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,01881991 0,10593789 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01881991 0,10569435 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,0196158 0,10991147 ! neural tube development GO:0021915 91 47 1,000 0,02042562 0,11418715 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,02042562 0,11392645 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02124922 0,1182502 ! cellular component disassembly GO:0022411 89 48 1,000 0,02124922 0,11798145 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,02124922 0,11771392 ! endosome transport GO:0016197 127 48 1,000 0,02124922 0,1174476 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02124922 0,11718248 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,02124922 0,11691855 ! protein homooligomerization GO:0051260 84 49 1,000 0,02208645 0,12125215 ! regulation of action potential GO:0001508 102 50 1,000 0,02293718 0,12564022 ! regulation of ion transport GO:0043269 86 50 1,000 0,02293718 0,12535915 ! regulation of ossification GO:0030278 123 50 1,000 0,02293718 0,12507933 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02313553 0,12587996 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02313553 0,12560023 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02313553 0,12532174 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02313553 0,12504447 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02313553 0,12476844 ! neuron fate determination GO:0048664 7 5 0,000 0,02313553 0,12449362 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02313553 0,12422001 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02313553 0,12394759 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02313553 0,12367637 ! polyol transport GO:0015791 12 5 0,000 0,02313553 0,12340634 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02313553 0,12313748 ! response to superoxide GO:0000303 10 5 0,000 0,02313553 0,12286979 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02313553 0,12260326 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02313553 0,12233788 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02313553 0,12207366 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02313553 0,12181057 ! female meiosis GO:0007143 10 5 0,000 0,02313553 0,12154861 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02313553 0,12128777 ! hypothalamus development GO:0021854 9 5 0,000 0,02313553 0,12102806 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02313553 0,12076945 ! cobalt ion transport GO:0006824 11 5 0,000 0,02313553 0,12051195 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02313553 0,12025554 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02313553 0,12000022 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02313553 0,11974598 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02313553 0,11949282 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02313553 0,11924072 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02313553 0,11898969 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02313553 0,11873971 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02313553 0,11849078 ! transposition GO:0032196 9 5 0,000 0,02313553 0,11824289 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02313553 0,11799604 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02313553 0,11775021 ! negative chemotaxis GO:0050919 16 5 0,000 0,02313553 0,11750541 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02313553 0,11726162 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02313553 0,11701885 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02313553 0,11677707 ! behavioral response to pain GO:0048266 10 5 0,000 0,02313553 0,11653629 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02313553 0,11629651 ! Notch receptor processing GO:0007220 11 5 0,000 0,02313553 0,11605771 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02313553 0,11581988 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02313553 0,11558303 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02313553 0,11534715 ! copulation GO:0007620 9 5 0,000 0,02313553 0,11511223 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02313553 0,11487826 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02313553 0,11464524 ! bioluminescence GO:0008218 9 5 0,000 0,02313553 0,11441316 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02313553 0,11418203 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02313553 0,11395182 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02313553 0,11372254 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02313553 0,11349418 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02313553 0,11326674 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02313553 0,11304021 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02313553 0,11281458 ! grooming behavior GO:0007625 6 5 0,000 0,02313553 0,11258985 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02313553 0,11236601 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02313553 0,11214306 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02313553 0,111921 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02313553 0,11169981 ! response to protozoan GO:0001562 13 5 0,000 0,02313553 0,11147949 ! lymph vessel development GO:0001945 10 5 0,000 0,02313553 0,11126004 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02313553 0,11104146 ! endochondral ossification GO:0001958 17 5 0,000 0,02313553 0,11082373 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02313553 0,11060685 ! single strand break repair GO:0000012 8 5 0,000 0,02313553 0,11039083 ! parathyroid gland development GO:0060017 14 5 0,000 0,02313553 0,11017564 ! anagen GO:0042640 7 5 0,000 0,02313553 0,10996129 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02313553 0,10974777 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02313553 0,10953508 ! cytokine secretion GO:0050663 15 5 0,000 0,02313553 0,10932322 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02313553 0,10911217 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02313553 0,10890193 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02313553 0,1086925 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02313553 0,10848388 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02313553 0,10827606 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02313553 0,10806903 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02313553 0,10786279 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02313553 0,10765734 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02313553 0,10745267 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02313553 0,10724877 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02313553 0,10704565 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02313553 0,10684329 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02313553 0,1066417 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02313553 0,10644087 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02313553 0,10624079 ! valine metabolic process GO:0006573 12 5 0,000 0,02313553 0,10604147 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02313553 0,10584289 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02313553 0,10564505 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02313553 0,10544795 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02313553 0,10525159 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02313553 0,10505595 ! polyol catabolic process GO:0046174 9 5 0,000 0,02313553 0,10486104 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02313553 0,10466686 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02313553 0,10447339 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02313553 0,10428063 ! muscle cell migration GO:0014812 8 5 0,000 0,02313553 0,10408859 ! mitochondrial fission GO:0000266 8 5 0,000 0,02313553 0,10389725 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02313553 0,10370661 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02313553 0,10351667 ! mRNA transcription GO:0009299 10 5 0,000 0,02313553 0,10332743 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02313553 0,10313887 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02313553 0,10295101 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02313553 0,10276382 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02313553 0,10257732 ! monocyte activation GO:0042117 10 5 0,000 0,02313553 0,10239149 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02313553 0,10220633 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02313553 0,10202185 ! response to food GO:0032094 6 5 0,000 0,02313553 0,10183802 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02313553 0,10165486 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02313553 0,10147236 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02313553 0,10129051 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02313553 0,10110931 ! forebrain neuron development GO:0021884 13 5 0,000 0,02313553 0,10092875 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02313553 0,10074885 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02313553 0,10056958 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02313553 0,10039095 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02313553 0,10021295 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02313553 0,10003558 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02313553 0,09985884 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02313553 0,09968272 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02313553 0,09950722 ! lipid glycosylation GO:0030259 7 5 0,000 0,02313553 0,09933234 ! nucleobase transport GO:0015851 6 5 0,000 0,02313553 0,09915807 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02313553 0,09898442 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02313553 0,09881137 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02313553 0,09863892 ! basic amino acid transport GO:0015802 12 5 0,000 0,02313553 0,09846708 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02313553 0,09829583 ! actin nucleation GO:0045010 11 5 0,000 0,02313553 0,09812518 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02313553 0,09795512 ! depurination GO:0045007 5 5 0,000 0,02313553 0,09778564 ! depyrimidination GO:0045008 10 5 0,000 0,02313553 0,09761676 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02313553 0,09744845 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02313553 0,09728073 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02313553 0,09711358 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02313553 0,096947 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02313553 0,096781 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02313553 0,09661556 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02313553 0,09645069 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02313553 0,09628638 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02313553 0,09612262 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02313553 0,09595943 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02313553 0,09579678 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02313553 0,09563469 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02313553 0,09547315 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02313553 0,09531215 ! response to arsenic GO:0046685 11 5 0,000 0,02313553 0,09515169 ! mast cell degranulation GO:0043303 7 5 0,000 0,02313553 0,09499177 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02313553 0,09483239 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02313553 0,09467354 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02313553 0,09451522 ! response to mercury ion GO:0046689 8 5 0,000 0,02313553 0,09435743 ! response to cadmium ion GO:0046686 7 5 0,000 0,02313553 0,09420017 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02313553 0,09404343 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02313553 0,09388721 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02313553 0,09373151 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02313553 0,09357633 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02313553 0,09342166 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02313553 0,0932675 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02313553 0,09311384 ! decidualization GO:0046697 11 5 0,000 0,02313553 0,09296069 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02313553 0,09280805 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02313553 0,09265591 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02313553 0,09250426 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02313553 0,09235311 ! embryonic cleavage GO:0040016 6 5 0,000 0,02313553 0,09220245 ! peroxisome fission GO:0016559 5 5 0,000 0,02313553 0,09205228 ! histone demethylation GO:0016577 13 5 0,000 0,02313553 0,09190261 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02313553 0,09175341 ! mitotic recombination GO:0006312 9 5 0,000 0,02313553 0,0916047 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02313553 0,09145648 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02313553 0,09130873 ! metaphase plate congression GO:0051310 7 5 0,000 0,02313553 0,09116146 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02313553 0,09101466 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02313553 0,09086833 ! enteric nervous system development GO:0048484 8 5 0,000 0,02313553 0,09072248 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02313553 0,09057709 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02313553 0,09043216 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02313553 0,0902877 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02313553 0,0901437 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02313553 0,09000016 ! B cell homeostasis GO:0001782 13 5 0,000 0,02313553 0,08985708 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02313553 0,08971445 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02313553 0,08957227 ! metaphase GO:0051323 11 5 0,000 0,02313553 0,08943054 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02313553 0,08928926 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02313553 0,08914843 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02313553 0,08900804 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02313553 0,08886809 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02313553 0,08872858 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02313553 0,0885895 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02313553 0,08845086 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02313553 0,08831266 ! response to redox state GO:0051775 6 5 0,000 0,02313553 0,08817489 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02313553 0,08803754 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02313553 0,08790063 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02313553 0,08776413 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02313553 0,08762807 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02313553 0,08749242 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02313553 0,08735719 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02313553 0,08722238 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02313553 0,08708799 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02313553 0,086954 ! striatum development GO:0021756 14 5 0,000 0,02313553 0,08682043 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02313553 0,08668727 ! glial cell migration GO:0008347 10 5 0,000 0,02313553 0,08655452 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02313553 0,08642218 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02313553 0,08629023 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02313553 0,08615869 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02313553 0,08602755 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02313553 0,08589681 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02313553 0,08576647 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02313553 0,08563652 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02313553 0,08550696 ! neuroprotection GO:0043526 8 5 0,000 0,02313553 0,0853778 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02313553 0,08524902 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02313553 0,08512064 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02313553 0,08499264 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02313553 0,08486502 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02313553 0,08473778 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02313553 0,08461093 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02313553 0,08448446 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02313553 0,08435836 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02313553 0,08423264 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02313553 0,0841073 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02313553 0,08398232 ! spindle assembly GO:0051225 6 5 0,000 0,02313553 0,08385772 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02313553 0,08373349 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02313553 0,08360962 ! protein palmitoylation GO:0018345 12 5 0,000 0,02313553 0,08348612 ! drug metabolic process GO:0017144 7 5 0,000 0,02313553 0,08336298 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02313553 0,08324021 ! organ regeneration GO:0031100 7 5 0,000 0,02313553 0,0831178 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02313553 0,08299575 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02313553 0,08287405 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,02380126 0,08513395 ! positive regulation of binding GO:0051099 88 52 1,000 0,02467855 0,08814285 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02467855 0,08801417 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,02467855 0,08788587 ! histone modification GO:0016570 104 52 1,000 0,02467855 0,08775794 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,02467855 0,08763039 ! positive regulation of growth GO:0045927 96 53 1,000 0,02556891 0,09066016 ! inner ear development GO:0048839 89 53 1,000 0,02556891 0,09052877 ! vesicle organization GO:0016050 127 53 1,000 0,02556891 0,09039776 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,0264722 0,09345605 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,0264722 0,09332119 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,0264722 0,09318672 ! covalent chromatin modification GO:0016569 115 54 1,000 0,0264722 0,09305264 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,02738828 0,09613443 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02769839 0,09708346 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02769839 0,09694437 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02769839 0,09680568 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02769839 0,09666739 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02769839 0,09652949 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02769839 0,09639198 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02769839 0,09625487 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02769839 0,09611814 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02769839 0,0959818 ! response to oxygen radical GO:0000305 11 6 0,000 0,02769839 0,09584585 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02769839 0,09571028 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02769839 0,0955751 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02769839 0,0954403 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02769839 0,09530587 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02769839 0,09517183 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02769839 0,09503816 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02769839 0,09490487 ! forebrain regionalization GO:0021871 9 6 0,000 0,02769839 0,09477195 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02769839 0,0946394 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02769839 0,09450722 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02769839 0,09437541 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02769839 0,09424397 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02769839 0,09411289 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02769839 0,09398218 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02769839 0,09385183 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02769839 0,09372184 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02769839 0,09359221 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02769839 0,09346294 ! malate metabolic process GO:0006108 13 6 0,000 0,02769839 0,09333403 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02769839 0,09320547 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02769839 0,09307726 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02769839 0,09294941 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02769839 0,09282191 ! protein refolding GO:0042026 15 6 0,000 0,02769839 0,09269475 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02769839 0,09256795 ! opsonization GO:0008228 8 6 0,000 0,02769839 0,09244149 ! mating behavior GO:0007617 7 6 0,000 0,02769839 0,09231538 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02769839 0,09218961 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02769839 0,09206418 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02769839 0,09193909 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02769839 0,09181434 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02769839 0,09168993 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02769839 0,09156586 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02769839 0,09144212 ! toxin metabolic process GO:0009404 11 6 0,000 0,02769839 0,09131872 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02769839 0,09119565 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02769839 0,09107291 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02769839 0,0909505 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02769839 0,09082842 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02769839 0,09070666 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02769839 0,09058524 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02769839 0,09046413 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02769839 0,09034335 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02769839 0,09022289 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02769839 0,09010276 ! protein lipoylation GO:0009249 10 6 0,000 0,02769839 0,08998294 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02769839 0,08986344 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02769839 0,08974426 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02769839 0,08962539 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02769839 0,08950684 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02769839 0,0893886 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02769839 0,08927067 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02769839 0,08915306 ! hyperosmotic response GO:0006972 10 6 0,000 0,02769839 0,08903575 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02769839 0,08891875 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02769839 0,08880206 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02769839 0,08868568 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02769839 0,0885696 ! urea metabolic process GO:0019627 7 6 0,000 0,02769839 0,08845382 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02769839 0,08833834 ! neutrophil activation GO:0042119 7 6 0,000 0,02769839 0,08822317 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02769839 0,0881083 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02769839 0,08799372 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02769839 0,08787944 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02769839 0,08776546 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02769839 0,08765178 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02769839 0,08753838 ! neuron apoptosis GO:0051402 15 6 0,000 0,02769839 0,08742529 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02769839 0,08731248 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02769839 0,08719996 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02769839 0,08708774 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02769839 0,0869758 ! carnitine transport GO:0015879 10 6 0,000 0,02769839 0,08686415 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02769839 0,08675278 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02769839 0,0866417 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02769839 0,08653091 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02769839 0,0864204 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02769839 0,08631017 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02769839 0,08620022 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02769839 0,08609055 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02769839 0,08598116 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02769839 0,08587204 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02769839 0,08576321 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02769839 0,08565465 ! response to UV-C GO:0010225 14 6 0,000 0,02769839 0,08554636 ! astrocyte development GO:0014002 16 6 0,000 0,02769839 0,08543835 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02769839 0,08533061 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02769839 0,08522314 ! interaction with symbiont GO:0051702 14 6 0,000 0,02769839 0,08511594 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02769839 0,08500901 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02769839 0,08490235 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02769839 0,08479595 ! response to copper ion GO:0046688 10 6 0,000 0,02769839 0,08468983 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02769839 0,08458396 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02769839 0,08447837 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02769839 0,08437303 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02769839 0,08426796 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02769839 0,08416315 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02769839 0,0840586 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02769839 0,08395431 ! hair follicle maturation GO:0048820 8 6 0,000 0,02769839 0,08385027 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02769839 0,0837465 ! Schwann cell development GO:0014044 15 6 0,000 0,02769839 0,08364298 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02769839 0,08353972 ! response to pheromone GO:0019236 6 6 0,000 0,02769839 0,08343671 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02769839 0,08333395 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02769839 0,08323145 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02769839 0,0831292 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02769839 0,0830272 ! subpallium development GO:0021544 15 6 0,000 0,02769839 0,08292545 ! neural tube patterning GO:0021532 8 6 0,000 0,02769839 0,08282395 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02769839 0,0827227 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02769839 0,0826217 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02769839 0,08252094 ! G2 phase GO:0051319 16 6 0,000 0,02769839 0,08242043 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02769839 0,08232016 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02769839 0,08222013 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02769839 0,08212035 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02769839 0,08202081 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02769839 0,08192151 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02769839 0,08182246 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02769839 0,08172364 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02769839 0,08162506 ! receptor internalization GO:0031623 11 6 0,000 0,02769839 0,08152671 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02769839 0,08142861 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02769839 0,08133073 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02769839 0,0812331 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02769839 0,0811357 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02769839 0,08103853 ! protein deubiquitination GO:0016579 16 6 0,000 0,02769839 0,08094159 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02769839 0,08084489 ! protein destabilization GO:0031648 9 6 0,000 0,02769839 0,08074841 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02769839 0,08065217 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02769839 0,08055616 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02769839 0,08046037 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02769839 0,08036481 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02769839 0,08026948 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02769839 0,08017437 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02769839 0,08007949 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02769839 0,07998484 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02769839 0,0798904 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02769839 0,07979619 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02769839 0,0797022 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02769839 0,07960844 ! neural plate development GO:0001840 9 6 0,000 0,02769839 0,07951489 ! catecholamine transport GO:0051937 9 6 0,000 0,02769839 0,07942156 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02769839 0,07932845 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02769839 0,07923556 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02769839 0,07914289 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02769839 0,07905043 ! maternal placenta development GO:0001893 12 6 0,000 0,02769839 0,07895819 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02769839 0,07886617 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02769839 0,07877435 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02769839 0,07868276 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02769839 0,07859137 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02769839 0,0785002 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02769839 0,07840924 GO:0055081|anion homeostasis, ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02831701 0,08006765 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02831701 0,07997509 ! regulation of DNA replication GO:0006275 105 56 1,000 0,02831701 0,07988274 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02925825 0,08244281 ! heart morphogenesis GO:0003007 105 57 1,000 0,02925825 0,08234783 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,03021188 0,08493398 ! aging GO:0007568 112 58 1,000 0,03021188 0,08483635 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,03021188 0,08473895 ! maintenance of location GO:0051235 124 58 1,000 0,03021188 0,08464177 ! nuclear export GO:0051168 110 59 1,000 0,03117775 0,08724771 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03117775 0,08714789 ! DNA catabolic process GO:0006308 94 60 1,000 0,03215574 0,08977882 ! kidney development GO:0001822 133 60 1,000 0,03215574 0,08967633 ! tRNA transcription GO:0009304 17 7 0,000 0,03224007 0,08980899 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03224007 0,0897067 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03224007 0,08960465 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03224007 0,08950282 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03224007 0,08940123 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03224007 0,08929987 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03224007 0,08919874 ! sleep GO:0030431 16 7 0,000 0,03224007 0,08909783 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03224007 0,08899716 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03224007 0,08889671 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03224007 0,08879649 ! prostate gland development GO:0030850 14 7 0,000 0,03224007 0,08869649 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03224007 0,08859672 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03224007 0,08849717 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03224007 0,08839785 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03224007 0,08829875 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03224007 0,08819987 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03224007 0,08810121 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03224007 0,08800278 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03224007 0,08790456 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03224007 0,08780656 ! glycolipid transport GO:0046836 11 7 0,000 0,03224007 0,08770878 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03224007 0,08761122 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03224007 0,08751387 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03224007 0,08741674 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03224007 0,08731983 ! mRNA stabilization GO:0048255 18 7 0,000 0,03224007 0,08722313 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03224007 0,08712664 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03224007 0,08703037 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03224007 0,08693431 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03224007 0,08683846 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03224007 0,08674282 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03224007 0,0866474 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03224007 0,08655218 ! lipoprotein transport GO:0042953 14 7 0,000 0,03224007 0,08645717 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03224007 0,08636237 ! rhythmic behavior GO:0007622 17 7 0,000 0,03224007 0,08626778 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03224007 0,0861734 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03224007 0,08607922 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03224007 0,08598524 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03224007 0,08589148 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03224007 0,08579791 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03224007 0,08570455 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03224007 0,0856114 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03224007 0,08551844 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03224007 0,08542569 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03224007 0,08533314 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03224007 0,08524078 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03224007 0,08514863 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03224007 0,08505668 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03224007 0,08496492 ! spinal cord patterning GO:0021511 14 7 0,000 0,03224007 0,08487337 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03224007 0,08478201 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03224007 0,08469084 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03224007 0,08459988 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03224007 0,0845091 ! adrenal gland development GO:0030325 17 7 0,000 0,03224007 0,08441853 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03224007 0,08432814 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03224007 0,08423795 ! ovulation GO:0030728 10 7 0,000 0,03224007 0,08414795 ! adenohypophysis development GO:0021984 11 7 0,000 0,03224007 0,08405815 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03224007 0,08396853 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03224007 0,08387911 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03224007 0,08378988 ! microtubule nucleation GO:0007020 21 7 0,000 0,03224007 0,08370083 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03224007 0,08361198 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03224007 0,08352331 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03224007 0,08343484 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03224007 0,08334654 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03224007 0,08325844 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03224007 0,08317052 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03224007 0,08308279 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03224007 0,08299524 ! galactose metabolic process GO:0006012 13 7 0,000 0,03224007 0,08290788 ! vesicle fusion GO:0006906 20 7 0,000 0,03224007 0,0828207 ! response to dietary excess GO:0002021 8 7 0,000 0,03224007 0,0827337 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03224007 0,08264689 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03224007 0,08256026 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03224007 0,08247381 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03224007 0,08238754 ! organ growth GO:0035265 15 7 0,000 0,03224007 0,08230145 ! nucleoside transport GO:0015858 11 7 0,000 0,03224007 0,08221554 ! nucleoside salvage GO:0043174 11 7 0,000 0,03224007 0,08212981 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03224007 0,08204425 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03224007 0,08195888 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03224007 0,08187368 ! parturition GO:0007567 16 7 0,000 0,03224007 0,08178866 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03224007 0,08170382 ! rRNA modification GO:0000154 14 7 0,000 0,03224007 0,08161915 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03224007 0,08153466 ! spindle checkpoint GO:0031577 16 7 0,000 0,03224007 0,08145035 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03224007 0,0813662 ! monocyte differentiation GO:0030224 16 7 0,000 0,03224007 0,08128223 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03224007 0,08119844 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03224007 0,08111481 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03224007 0,08103136 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03224007 0,08094808 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03224007 0,08086497 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03224007 0,08078204 ! fibrinolysis GO:0042730 11 7 0,000 0,03224007 0,08069927 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03224007 0,08061667 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03224007 0,08053424 ! eating behavior GO:0042755 8 7 0,000 0,03224007 0,08045198 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03224007 0,08036988 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03224007 0,08028796 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03224007 0,0802062 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03224007 0,0801246 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03224007 0,08004318 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03224007 0,07996191 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03224007 0,07988082 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03224007 0,07979988 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03224007 0,07971911 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03224007 0,07963851 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03224007 0,07955807 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03224007 0,07947778 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03224007 0,07939767 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03224007 0,07931771 ! histone ubiquitination GO:0016574 9 7 0,000 0,03224007 0,07923791 ! regulation of meiosis GO:0040020 12 7 0,000 0,03224007 0,07915828 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03224007 0,0790788 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03224007 0,07899948 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03224007 0,07892033 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03224007 0,07884133 ! transcription termination GO:0006353 14 7 0,000 0,03224007 0,07876248 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03224007 0,0786838 ! anaphase GO:0051322 18 7 0,000 0,03224007 0,07860527 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03224007 0,0785269 ! axonal fasciculation GO:0007413 19 7 0,000 0,03224007 0,07844869 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03224007 0,07837063 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03224007 0,07829273 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03224007 0,07821498 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03224007 0,07813739 ! diuresis GO:0030146 12 7 0,000 0,03224007 0,07805994 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03224007 0,07798266 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03224007 0,07790552 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03224007 0,07782854 ! antibiotic transport GO:0042891 9 7 0,000 0,03224007 0,07775171 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03224007 0,07767503 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03224007 0,07759851 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03224007 0,07752213 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03224007 0,0774459 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03224007 0,07736983 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03224007 0,0772939 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03224007 0,07721812 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03224007 0,07714249 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03224007 0,07706701 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03224007 0,07699168 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03224007 0,07691649 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03224007 0,07684145 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03224007 0,07676655 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03224007 0,07669181 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03224007 0,0766172 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03224007 0,07654274 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03224007 0,07646843 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03224007 0,07639426 ! muscle adaptation GO:0043500 13 7 0,000 0,03224007 0,07632024 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03224007 0,07624635 ! retina homeostasis GO:0001895 12 7 0,000 0,03224007 0,07617262 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03224007 0,07609902 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03224007 0,07602556 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03224007 0,07595225 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,0331457 0,07801055 ! viral reproductive process GO:0022415 132 62 1,000 0,03414751 0,08029103 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,03516104 0,08259464 ! regulation of mitosis GO:0007088 112 63 1,000 0,03516104 0,0825153 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,03516104 0,08243611 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,03618616 0,08475818 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03676066 0,08602134 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03676066 0,08593903 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03676066 0,08585687 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03676066 0,08577486 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03676066 0,08569302 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03676066 0,08561133 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03676066 0,08552979 ! male meiosis GO:0007140 9 8 0,000 0,03676066 0,08544841 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03676066 0,08536719 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03676066 0,08528612 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03676066 0,0852052 ! meiotic prophase I GO:0007128 14 8 0,000 0,03676066 0,08512444 ! response to zinc ion GO:0010043 12 8 0,000 0,03676066 0,08504383 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03676066 0,08496337 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03676066 0,08488306 ! oligopeptide transport GO:0006857 16 8 0,000 0,03676066 0,08480291 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03676066 0,08472291 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03676066 0,08464306 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03676066 0,08456335 ! signal peptide processing GO:0006465 12 8 0,000 0,03676066 0,0844838 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03676066 0,0844044 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03676066 0,08432515 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03676066 0,08424604 ! succinate metabolic process GO:0006105 17 8 0,000 0,03676066 0,08416709 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03676066 0,08408828 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03676066 0,08400962 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03676066 0,0839311 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03676066 0,08385274 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03676066 0,08377452 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03676066 0,08369644 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03676066 0,08361851 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03676066 0,08354073 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03676066 0,08346309 ! reflex GO:0060004 17 8 0,000 0,03676066 0,08338559 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03676066 0,08330824 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03676066 0,08323103 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03676066 0,08315396 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03676066 0,08307704 ! pigment granule organization GO:0048753 17 8 0,000 0,03676066 0,08300026 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03676066 0,08292362 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03676066 0,08284712 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03676066 0,08277077 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03676066 0,08269455 ! histidine catabolic process GO:0006548 10 8 0,000 0,03676066 0,08261847 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03676066 0,08254254 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03676066 0,08246674 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03676066 0,08239108 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03676066 0,08231557 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03676066 0,08224018 ! melanin metabolic process GO:0006582 17 8 0,000 0,03676066 0,08216494 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03676066 0,08208984 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03676066 0,08201487 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03676066 0,08194004 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03676066 0,08186534 ! macrophage activation GO:0042116 13 8 0,000 0,03676066 0,08179078 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03676066 0,08171636 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03676066 0,08164207 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03676066 0,08156792 ! purine salvage GO:0043101 12 8 0,000 0,03676066 0,0814939 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03676066 0,08142002 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03676066 0,08134627 ! osteoblast development GO:0002076 17 8 0,000 0,03676066 0,08127265 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03676066 0,08119917 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03676066 0,08112582 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03676066 0,0810526 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03676066 0,08097951 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03676066 0,08090656 ! response to UV-B GO:0010224 17 8 0,000 0,03676066 0,08083374 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03676066 0,08076104 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03676066 0,08068848 ! intermediate filament organization GO:0045109 12 8 0,000 0,03676066 0,08061605 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03676066 0,08054375 ! cellular extravasation GO:0045123 13 8 0,000 0,03676066 0,08047158 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03676066 0,08039954 ! response to antibiotic GO:0046677 11 8 0,000 0,03676066 0,08032762 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03676066 0,08025584 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03676066 0,08018418 ! DNA topological change GO:0006265 12 8 0,000 0,03676066 0,08011265 ! response to tropane GO:0014073 15 8 0,000 0,03676066 0,08004125 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03676066 0,07996997 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03676066 0,07989883 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03676066 0,07982781 ! mast cell activation GO:0045576 14 8 0,000 0,03676066 0,07975691 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03676066 0,07968614 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03676066 0,0796155 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03676066 0,07954498 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03676066 0,07947459 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03676066 0,07940432 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03676066 0,07933417 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03676066 0,07926415 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03676066 0,07919425 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03676066 0,07912448 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03676066 0,07905483 ! response to tumor cell GO:0002347 16 8 0,000 0,03676066 0,0789853 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03676066 0,07891589 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03676066 0,0788466 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03676066 0,07877744 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03676066 0,0787084 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03676066 0,07863948 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03676066 0,07857068 ! hormone catabolic process GO:0042447 17 8 0,000 0,03676066 0,07850199 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03676066 0,07843343 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03676066 0,07836499 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03676066 0,07829667 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03676066 0,07822847 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03676066 0,07816038 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03676066 0,07809242 ! adult feeding behavior GO:0008343 10 8 0,000 0,03676066 0,07802457 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03676066 0,07795684 ! ATP catabolic process GO:0006200 11 8 0,000 0,03676066 0,07788923 ! blastocyst growth GO:0001832 19 8 0,000 0,03676066 0,07782173 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03676066 0,07775436 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03676066 0,07768709 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03676066 0,07761995 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03676066 0,07755292 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03676066 0,07748601 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03676066 0,07741921 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03676066 0,07735253 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03676066 0,07728596 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03676066 0,0772195 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03676066 0,07715316 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03676066 0,07708694 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03676066 0,07702082 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03676066 0,07695483 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03676066 0,07688894 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03676066 0,07682317 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03676066 0,07675751 ! ear development GO:0043583 114 66 1,000 0,03827063 0,07984215 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,03827063 0,07977403 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03932974 0,08191181 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,03932974 0,08184204 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,03932974 0,08177239 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,04039992 0,08392603 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,04039992 0,08385473 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,04039992 0,08378354 ! viral reproduction GO:0016032 142 68 1,000 0,04039992 0,08371248 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,04039992 0,08364154 ! cell projection assembly GO:0030031 138 68 1,000 0,04039992 0,08357071 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04126025 0,08527817 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04126025 0,08520609 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04126025 0,08513412 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04126025 0,08506228 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04126025 0,08499056 ! reproductive behavior GO:0019098 22 9 0,000 0,04126025 0,08491896 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04126025 0,08484748 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04126025 0,08477612 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04126025 0,08470487 ! UTP metabolic process GO:0046051 10 9 0,000 0,04126025 0,08463375 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04126025 0,08456275 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04126025 0,08449187 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04126025 0,08442111 ! artery development GO:0060840 25 9 0,000 0,04126025 0,08435046 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04126025 0,08427993 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04126025 0,08420952 ! equilibrioception GO:0050957 20 9 0,000 0,04126025 0,08413923 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04126025 0,08406906 ! chemosensory behavior GO:0007635 21 9 0,000 0,04126025 0,083999 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04126025 0,08392906 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04126025 0,08385924 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04126025 0,08378953 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04126025 0,08371993 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04126025 0,08365046 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04126025 0,0835811 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04126025 0,08351185 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04126025 0,08344272 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04126025 0,0833737 ! protein targeting to ER GO:0045047 25 9 0,000 0,04126025 0,08330479 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04126025 0,083236 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04126025 0,08316733 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04126025 0,08309876 ! glycine catabolic process GO:0006546 15 9 0,000 0,04126025 0,08303031 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04126025 0,08296198 ! endosome organization GO:0007032 20 9 0,000 0,04126025 0,08289375 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04126025 0,08282564 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04126025 0,08275764 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04126025 0,08268975 ! mannose metabolic process GO:0006013 13 9 0,000 0,04126025 0,08262197 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04126025 0,0825543 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04126025 0,08248674 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04126025 0,0824193 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04126025 0,08235196 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04126025 0,08228474 ! retinol metabolic process GO:0042572 20 9 0,000 0,04126025 0,08221762 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04126025 0,08215061 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04126025 0,08208371 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04126025 0,08201692 ! macrophage differentiation GO:0030225 15 9 0,000 0,04126025 0,08195024 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04126025 0,08188367 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04126025 0,08181721 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04126025 0,08175085 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04126025 0,0816846 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04126025 0,08161846 ! response to amine stimulus GO:0014075 13 9 0,000 0,04126025 0,08155243 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04126025 0,0814865 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04126025 0,08142068 ! erythrocyte development GO:0048821 17 9 0,000 0,04126025 0,08135496 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04126025 0,08128936 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04126025 0,08122385 ! renal water homeostasis GO:0003091 15 9 0,000 0,04126025 0,08115845 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04126025 0,08109316 ! icosanoid secretion GO:0032309 15 9 0,000 0,04126025 0,08102797 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04126025 0,08096289 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04126025 0,08089791 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04126025 0,08083304 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04126025 0,08076827 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04126025 0,0807036 ! sterol catabolic process GO:0016127 14 9 0,000 0,04126025 0,08063904 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04126025 0,08057458 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04126025 0,08051022 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04126025 0,08044597 ! S phase GO:0051320 10 9 0,000 0,04126025 0,08038182 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04126025 0,08031777 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04126025 0,08025382 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04126025 0,08018998 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04126025 0,08012623 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04126025 0,08006259 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04126025 0,07999905 ! purine base metabolic process GO:0006144 25 9 0,000 0,04126025 0,07993561 ! pigment granule transport GO:0051904 17 9 0,000 0,04126025 0,07987227 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04126025 0,07980903 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04126025 0,07974589 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04126025 0,07968285 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04126025 0,07961991 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04126025 0,07955706 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04126025 0,07949432 ! mitochondrion localization GO:0051646 18 9 0,000 0,04126025 0,07943168 ! lung development GO:0030324 165 69 1,000 0,04148106 0,07979388 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,04148106 0,0797311 ! urogenital system development GO:0001655 149 69 1,000 0,04148106 0,07966842 ! activation of immune response GO:0002253 120 70 1,000 0,04257302 0,08170141 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,04367569 0,08375173 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,04367569 0,08368604 ! appendage morphogenesis GO:0035107 150 72 1,000 0,04478894 0,08575186 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 0,04478894 0,08568471 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,04478894 0,08561766 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,04478894 0,08555072 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04573896 0,08729709 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04573896 0,08722894 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04573896 0,0871609 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04573896 0,08709297 ! associative learning GO:0008306 21 10 0,000 0,04573896 0,08702514 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04573896 0,08695741 ! phosphate transport GO:0006817 24 10 0,000 0,04573896 0,0868898 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04573896 0,08682228 ! CTP metabolic process GO:0046036 11 10 0,000 0,04573896 0,08675487 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04573896 0,08668757 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04573896 0,08662037 ! GTP metabolic process GO:0046039 11 10 0,000 0,04573896 0,08655328 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04573896 0,08648628 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04573896 0,0864194 ! social behavior GO:0035176 29 10 0,000 0,04573896 0,08635261 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04573896 0,08628593 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04573896 0,08621935 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04573896 0,08615287 ! androgen metabolic process GO:0008209 17 10 0,000 0,04573896 0,0860865 ! phospholipid efflux GO:0033700 19 10 0,000 0,04573896 0,08602023 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04573896 0,08595406 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04573896 0,08588799 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04573896 0,08582203 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04573896 0,08575616 ! lung alveolus development GO:0048286 26 10 0,000 0,04573896 0,0856904 ! pathogenesis GO:0009405 17 10 0,000 0,04573896 0,08562473 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04573896 0,08555917 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04573896 0,08549371 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04573896 0,08542835 ! endoderm development GO:0007492 18 10 0,000 0,04573896 0,08536308 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04573896 0,08529792 ! arginine catabolic process GO:0006527 17 10 0,000 0,04573896 0,08523286 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04573896 0,08516789 ! proline metabolic process GO:0006560 13 10 0,000 0,04573896 0,08510303 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04573896 0,08503826 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04573896 0,0849736 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04573896 0,08490903 ! V(D)J recombination GO:0033151 34 10 0,000 0,04573896 0,08484455 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04573896 0,08478018 ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04573896 0,0847159 ! B cell proliferation GO:0042100 19 10 0,000 0,04573896 0,08465173 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04573896 0,08458764 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04573896 0,08452366 ! multicellular organism growth GO:0035264 19 10 0,000 0,04573896 0,08445977 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04573896 0,08439598 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04573896 0,08433229 ! ruffle organization GO:0031529 17 10 0,000 0,04573896 0,08426869 ! epithelial cell development GO:0002064 21 10 0,000 0,04573896 0,08420518 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04573896 0,08414178 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04573896 0,08407846 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04573896 0,08401525 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04573896 0,08395212 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04573896 0,0838891 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04573896 0,08382617 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04573896 0,08376333 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04573896 0,08370058 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04573896 0,08363793 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04573896 0,08357538 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04573896 0,08351291 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04573896 0,08345054 ! segment specification GO:0007379 15 10 0,000 0,04573896 0,08338827 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04573896 0,08332608 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04573896 0,08326399 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04573896 0,08320199 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04573896 0,08314009 ! response to dsRNA GO:0043331 23 10 0,000 0,04573896 0,08307827 ! DNA ligation GO:0006266 18 10 0,000 0,04573896 0,08301655 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04573896 0,08295492 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04573896 0,08289338 ! melanosome localization GO:0032400 16 10 0,000 0,04573896 0,08283193 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04573896 0,08277058 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04573896 0,08270931 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04573896 0,08264813 ! induction of an organ GO:0001759 17 10 0,000 0,04573896 0,08258705 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04573896 0,08252605 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04573896 0,08246515 ! protein sumoylation GO:0016925 17 10 0,000 0,04573896 0,08240433 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04573896 0,08234361 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04573896 0,08228297 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04573896 0,08222243 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04573896 0,08216197 ! salivary gland development GO:0007431 28 10 0,000 0,04573896 0,0821016 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04573896 0,08204132 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04573896 0,08198113 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04573896 0,08192103 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04573896 0,08186101 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04573896 0,08180108 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04573896 0,08174124 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04573896 0,08168149 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04573896 0,08162182 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04573896 0,08156225 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04573896 0,08150276 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04573896 0,08144335 ! detection of calcium ion GO:0005513 24 10 0,000 0,04573896 0,08138403 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04573896 0,0813248 ! blastocyst formation GO:0001825 18 10 0,000 0,04573896 0,08126566 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04573896 0,0812066 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04573896 0,08114762 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04573896 0,08108874 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04573896 0,08102993 ! response to nicotine GO:0035094 20 10 0,000 0,04573896 0,08097122 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04573896 0,08091258 ! appendage development GO:0048736 151 73 1,000 0,04591264 0,08116106 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,04591264 0,08110238 ! regulation of immune effector process GO:0002697 156 73 1,000 0,04591264 0,08104378 ! respiratory system development GO:0060541 175 74 1,000 0,04704669 0,08298561 ! organelle localization GO:0051640 155 74 1,000 0,04704669 0,08292574 ! transition metal ion transport GO:0000041 143 75 1,000 0,04819096 0,08488141 ! axon guidance GO:0007411 162 75 1,000 0,04819096 0,08482026 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,04934533 0,08678952 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,04934533 0,08672708 ! respiratory burst GO:0045730 17 11 0,000 0,05019687 0,08816028 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05019687 0,08809695 ! neuron fate specification GO:0048665 18 11 0,000 0,05019687 0,0880337 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05019687 0,08797055 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05019687 0,08790749 ! thyroid gland development GO:0030878 26 11 0,000 0,05019687 0,08784452 ! synapsis GO:0007129 14 11 0,000 0,05019687 0,08778164 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05019687 0,08771885 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05019687 0,08765615 ! response to pain GO:0048265 27 11 0,000 0,05019687 0,08759354 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05019687 0,08753101 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05019687 0,08746858 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05019687 0,08740624 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05019687 0,08734398 ! bone resorption GO:0045453 16 11 0,000 0,05019687 0,08728181 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05019687 0,08721974 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05019687 0,08715775 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05019687 0,08709584 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05019687 0,08703403 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05019687 0,0869723 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05019687 0,08691067 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05019687 0,08684911 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05019687 0,08678765 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05019687 0,08672627 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05019687 0,08666498 ! UV protection GO:0009650 20 11 0,000 0,05019687 0,08660378 ! adult heart development GO:0007512 16 11 0,000 0,05019687 0,08654266 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05019687 0,08648163 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05019687 0,08642068 ! macroautophagy GO:0016236 19 11 0,000 0,05019687 0,08635982 ! temperature homeostasis GO:0001659 18 11 0,000 0,05019687 0,08629905 ! behavioral fear response GO:0001662 27 11 0,000 0,05019687 0,08623836 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05019687 0,08617776 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05019687 0,08611724 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05019687 0,08605681 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05019687 0,08599646 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05019687 0,08593619 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05019687 0,08587602 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05019687 0,08581592 ! regulation of organ growth GO:0046620 14 11 0,000 0,05019687 0,08575591 ! pigment granule localization GO:0051875 20 11 0,000 0,05019687 0,08569598 ! vasoconstriction GO:0042310 20 11 0,000 0,05019687 0,08563614 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05019687 0,08557638 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05019687 0,0855167 ! embryonic axis specification GO:0000578 19 11 0,000 0,05019687 0,08545711 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05019687 0,0853976 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05019687 0,08533817 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05019687 0,08527882 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05019687 0,08521956 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05019687 0,08516038 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05019687 0,08510128 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05019687 0,08504227 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05019687 0,08498333 ! prophase GO:0051324 17 11 0,000 0,05019687 0,08492448 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05019687 0,08486571 ! nucleosome positioning GO:0016584 15 11 0,000 0,05019687 0,08480702 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05019687 0,08474841 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05019687 0,08468988 ! apical protein localization GO:0045176 18 11 0,000 0,05019687 0,08463144 ! acid secretion GO:0046717 20 11 0,000 0,05019687 0,08457307 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05019687 0,08451478 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05019687 0,08445658 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05019687 0,08439845 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05019687 0,08434041 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05019687 0,08428244 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05019687 0,08422455 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05019687 0,08416675 ! cholesterol efflux GO:0033344 21 11 0,000 0,05019687 0,08410902 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05019687 0,08405137 ! oocyte development GO:0048599 20 11 0,000 0,05019687 0,0839938 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05019687 0,08393631 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05019687 0,0838789 ! embryonic gut development GO:0048566 19 11 0,000 0,05019687 0,08382156 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05019687 0,08376431 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05019687 0,08370713 ! activation of innate immune response GO:0002218 16 11 0,000 0,05019687 0,08365003 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05019687 0,08359301 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05019687 0,08353607 ! lysogeny GO:0030069 22 11 0,000 0,05019687 0,0834792 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05019687 0,08342241 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05019687 0,0833657 ! nucleus localization GO:0051647 22 11 0,000 0,05019687 0,08330907 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,05050968 0,08377132 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,05050968 0,08371448 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,05406146 0,08954044 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05463408 0,09042754 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05463408 0,09036632 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05463408 0,09030518 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05463408 0,09024412 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05463408 0,09018314 ! protein complex disassembly GO:0043241 28 12 0,000 0,05463408 0,09012225 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 29 12 0,000 0,05463408 0,09006144 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05463408 0,09000071 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05463408 0,08994006 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05463408 0,08987949 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05463408 0,08981901 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05463408 0,08975861 ! drug transport GO:0015893 16 12 0,000 0,05463408 0,08969829 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05463408 0,08963805 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05463408 0,08957789 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05463408 0,08951781 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05463408 0,08945781 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05463408 0,08939789 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05463408 0,08933805 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05463408 0,08927829 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05463408 0,08921862 ! lipid digestion GO:0044241 21 12 0,000 0,05463408 0,08915902 ! entry into host cell GO:0030260 34 12 0,000 0,05463408 0,0890995 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05463408 0,08904006 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05463408 0,0889807 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05463408 0,08892142 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05463408 0,08886222 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05463408 0,08880309 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05463408 0,08874405 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05463408 0,08868508 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05463408 0,08862619 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05463408 0,08856738 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05463408 0,08850865 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05463408 0,08845 ! cranial nerve development GO:0021545 23 12 0,000 0,05463408 0,08839142 ! fucose catabolic process GO:0019317 25 12 0,000 0,05463408 0,08833292 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05463408 0,0882745 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05463408 0,08821616 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05463408 0,08815789 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05463408 0,0880997 ! zymogen activation GO:0031638 18 12 0,000 0,05463408 0,08804159 ! T cell homeostasis GO:0043029 28 12 0,000 0,05463408 0,08798355 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05463408 0,08792559 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05463408 0,08786771 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,05463408 0,0878099 ! oocyte differentiation GO:0009994 21 12 0,000 0,05463408 0,08775217 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05463408 0,08769451 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05463408 0,08763693 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,05463408 0,08757943 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05463408 0,087522 ! defense response to fungus GO:0050832 15 12 0,000 0,05463408 0,08746465 ! developmental induction GO:0031128 22 12 0,000 0,05463408 0,08740737 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05463408 0,08735016 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05463408 0,08729303 ! response to cold GO:0009409 17 12 0,000 0,05463408 0,08723598 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05463408 0,087179 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05463408 0,08712209 ! meiosis GO:0007126 143 81 1,000 0,05526458 0,08807004 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,05526458 0,08801263 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,05647711 0,08988506 ! meiotic cell cycle GO:0051321 144 82 1,000 0,05647711 0,08982654 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,05769892 0,09171013 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,05769892 0,0916505 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05905068 0,09373672 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05905068 0,09367585 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05905068 0,09361506 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05905068 0,09355435 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05905068 0,09349372 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05905068 0,09343317 ! peroxisomal transport GO:0043574 28 13 0,000 0,05905068 0,09337269 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05905068 0,0933123 ! cartilage condensation GO:0001502 22 13 0,000 0,05905068 0,09325198 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05905068 0,09319174 ! organelle fusion GO:0048284 36 13 0,000 0,05905068 0,09313158 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05905068 0,09307149 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05905068 0,09301148 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05905068 0,09295155 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05905068 0,0928917 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05905068 0,09283192 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05905068 0,09277223 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05905068 0,0927126 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05905068 0,09265306 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05905068 0,09259359 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05905068 0,0925342 ! methionine metabolic process GO:0006555 31 13 0,000 0,05905068 0,09247488 ! plasma membrane organization GO:0007009 27 13 0,000 0,05905068 0,09241564 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05905068 0,09235647 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05905068 0,09229738 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05905068 0,09223837 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05905068 0,09217943 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,05905068 0,09212057 ! cytokine metabolic process GO:0042107 24 13 0,000 0,05905068 0,09206178 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05905068 0,09200307 ! exocrine system development GO:0035272 34 13 0,000 0,05905068 0,09194443 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05905068 0,09188587 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05905068 0,09182738 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05905068 0,09176896 ! L-glutamate transport GO:0015813 30 13 0,000 0,05905068 0,09171062 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05905068 0,09165236 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05905068 0,09159417 ! protein homotetramerization GO:0051289 24 13 0,000 0,05905068 0,09153605 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05905068 0,091478 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05905068 0,09142003 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05905068 0,09136213 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05905068 0,09130431 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05905068 0,09124656 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05905068 0,09118888 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05905068 0,09113128 ! histone methylation GO:0016571 29 13 0,000 0,05905068 0,09107374 ! chromatin silencing GO:0006342 29 13 0,000 0,05905068 0,09101628 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05905068 0,0909589 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05905068 0,09090158 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05905068 0,09084434 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05905068 0,09078717 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05905068 0,09073007 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05905068 0,09067304 ! spleen development GO:0048536 24 13 0,000 0,05905068 0,09061609 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05905068 0,0905592 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05905068 0,09050239 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05905068 0,09044565 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05905068 0,09038898 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05905068 0,09033238 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05905068 0,09027585 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05905068 0,09021939 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05905068 0,09016301 ! insulin secretion GO:0030073 24 13 0,000 0,05905068 0,09010669 ! acrosome reaction GO:0007340 19 13 0,000 0,05905068 0,09005044 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05905068 0,08999427 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05905068 0,08993816 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,06016999 0,09158585 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,06141902 0,0934288 ! regulation of lyase activity GO:0051339 169 86 1,000 0,06141902 0,09337066 ! mitochondrion organization GO:0007005 159 87 1,000 0,06267689 0,09522366 ! rRNA transcription GO:0009303 28 14 0,000 0,06344677 0,09633342 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06344677 0,09627358 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,06344677 0,09621382 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06344677 0,09615414 ! non-recombinational repair GO:0000726 29 14 0,000 0,06344677 0,09609452 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06344677 0,09603499 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06344677 0,09597552 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06344677 0,09591613 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06344677 0,09585681 ! palate development GO:0060021 32 14 0,000 0,06344677 0,09579757 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06344677 0,0957384 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06344677 0,0956793 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06344677 0,09562028 ! arginine metabolic process GO:0006525 21 14 0,000 0,06344677 0,09556132 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06344677 0,09550244 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06344677 0,09544364 ! regulation of heart rate GO:0002027 25 14 0,000 0,06344677 0,0953849 ! fear response GO:0042596 34 14 0,000 0,06344677 0,09532624 ! organic alcohol transport GO:0015850 29 14 0,000 0,06344677 0,09526765 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06344677 0,09520913 ! embryo implantation GO:0007566 30 14 0,000 0,06344677 0,09515069 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06344677 0,09509231 ! bone mineralization GO:0030282 18 14 0,000 0,06344677 0,09503401 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06344677 0,09497578 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06344677 0,09491762 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06344677 0,09485953 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06344677 0,09480151 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06344677 0,09474356 ! ribosome assembly GO:0042255 18 14 0,000 0,06344677 0,09468568 ! cerebellum development GO:0021549 23 14 0,000 0,06344677 0,09462788 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06344677 0,09457014 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06344677 0,09451248 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06344677 0,09445489 ! response to gamma radiation GO:0010332 30 14 0,000 0,06344677 0,09439736 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06344677 0,09433991 ! NADP metabolic process GO:0006739 24 14 0,000 0,06344677 0,09428252 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06344677 0,09422521 ! oxygen transport GO:0015671 22 14 0,000 0,06344677 0,09416796 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06344677 0,09411079 ! male genitalia development GO:0030539 26 14 0,000 0,06344677 0,09405368 ! regulation of RNA stability GO:0043487 33 14 0,000 0,06344677 0,09399664 ! regulation of axon extension GO:0030516 43 14 0,000 0,06344677 0,09393968 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,06344677 0,09388278 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,06521876 0,09644638 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,06779473 0,10019511 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 1,000 0,06779473 0,10013453 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06782245 0,10011495 ! lactation GO:0007595 30 15 0,000 0,06782245 0,1000545 ! reproductive cellular process GO:0048610 22 15 0,000 0,06782245 0,09999411 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06782245 0,0999338 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06782245 0,09987357 ! superoxide anion generation GO:0042554 22 15 0,000 0,06782245 0,0998134 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06782245 0,09975331 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,06782245 0,09969329 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06782245 0,09963334 ! copper ion transport GO:0006825 22 15 0,000 0,06782245 0,09957347 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06782245 0,09951366 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06782245 0,09945393 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06782245 0,09939427 ! sulfate transport GO:0008272 27 15 0,000 0,06782245 0,09933468 ! response to cAMP GO:0051591 25 15 0,000 0,06782245 0,09927516 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06782245 0,09921572 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06782245 0,09915634 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06782245 0,09909704 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06782245 0,0990378 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06782245 0,09897864 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06782245 0,09891955 ! vesicle coating GO:0006901 38 15 0,000 0,06782245 0,09886053 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,06782245 0,09880158 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,06782245 0,0987427 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06782245 0,09868389 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06782245 0,09862515 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,06782245 0,09856648 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06782245 0,09850788 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06782245 0,09844934 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06782245 0,09839088 ! histone deacetylation GO:0016575 24 15 0,000 0,06782245 0,09833249 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06782245 0,09827417 ! water homeostasis GO:0030104 28 15 0,000 0,06782245 0,09821591 ! cofactor transport GO:0051181 30 15 0,000 0,06782245 0,09815773 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06782245 0,09809961 ! muscle maintenance GO:0046716 26 15 0,000 0,06782245 0,09804157 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06782245 0,09798359 ! intestinal absorption GO:0050892 31 15 0,000 0,06782245 0,09792568 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06782245 0,09786784 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06782245 0,09781006 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06782245 0,09775236 ! cell killing GO:0001906 32 15 0,000 0,06782245 0,09769472 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06782245 0,09763715 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06782245 0,09757965 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06782245 0,09752222 ! actin filament polymerization GO:0030041 27 15 0,000 0,06782245 0,09746485 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06782245 0,09740755 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,07040395 0,10105573 GO:0010498|proteasomal protein catabolic process, ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07217781 0,10354104 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07217781 0,10348027 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07217781 0,10341958 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07217781 0,10335896 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07217781 0,10329841 ! bone remodeling GO:0046849 28 16 0,000 0,07217781 0,10323793 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07217781 0,10317752 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07217781 0,10311718 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07217781 0,10305692 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07217781 0,10299672 ! startle response GO:0001964 28 16 0,000 0,07217781 0,10293659 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07217781 0,10287654 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07217781 0,10281655 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07217781 0,10275663 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07217781 0,10269679 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07217781 0,10263701 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07217781 0,1025773 ! pituitary gland development GO:0021983 30 16 0,000 0,07217781 0,10251767 ! response to osmotic stress GO:0006970 27 16 0,000 0,07217781 0,1024581 ! lysosomal transport GO:0007041 31 16 0,000 0,07217781 0,1023986 ! fructose metabolic process GO:0006000 25 16 0,000 0,07217781 0,10233917 ! L-amino acid transport GO:0015807 33 16 0,000 0,07217781 0,10227981 ! stem cell development GO:0048864 46 16 0,000 0,07217781 0,10222051 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07217781 0,10216129 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07217781 0,10210213 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07217781 0,10204305 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07217781 0,10198403 ! axon cargo transport GO:0008088 46 16 0,000 0,07217781 0,10192508 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07217781 0,1018662 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07217781 0,10180738 ! DNA replication initiation GO:0006270 28 16 0,000 0,07217781 0,10174863 ! neuron recognition GO:0008038 40 16 0,000 0,07217781 0,10168996 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07217781 0,10163135 ! tissue regeneration GO:0042246 27 16 0,000 0,07217781 0,1015728 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07217781 0,10151433 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07217781 0,10145592 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,07217781 0,10139758 ! biomineral formation GO:0031214 22 16 0,000 0,07217781 0,1013393 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07217781 0,10128109 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07217781 0,10122295 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07217781 0,10116488 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07217781 0,10110687 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07217781 0,10104893 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07217781 0,10099106 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07217781 0,10093325 ! peptide hormone processing GO:0016486 27 16 0,000 0,07217781 0,10087551 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,0730456 0,10202996 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,0730456 0,10197166 ! metencephalon development GO:0022037 32 17 0,000 0,07651294 0,10675106 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07651294 0,10669013 ! filopodium assembly GO:0046847 42 17 0,000 0,07651294 0,10662927 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07651294 0,10656848 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07651294 0,10650775 ! glial cell development GO:0021782 28 17 0,000 0,07651294 0,1064471 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,07651294 0,10638651 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07651294 0,106326 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07651294 0,10626555 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07651294 0,10620517 ! myoblast differentiation GO:0045445 50 17 0,000 0,07651294 0,10614486 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,07651294 0,10608462 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,07651294 0,10602445 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,07651294 0,10596435 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,07651294 0,10590431 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,07651294 0,10584434 ! NAD metabolic process GO:0019674 33 17 0,000 0,07651294 0,10578444 ! membrane budding GO:0006900 42 17 0,000 0,07651294 0,10572461 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07651294 0,10566484 ! regulation of protein binding GO:0043393 33 17 0,000 0,07651294 0,10560514 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07651294 0,10554551 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07651294 0,10548595 ! genitalia development GO:0048806 32 17 0,000 0,07651294 0,10542646 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07651294 0,10536703 ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07651294 0,10530767 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,07651294 0,10524837 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,07651294 0,10518914 ! steroid catabolic process GO:0006706 34 17 0,000 0,07651294 0,10512998 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,07651294 0,10507089 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07651294 0,10501186 ! gas transport GO:0015669 26 17 0,000 0,07651294 0,10495289 ! organic cation transport GO:0015695 32 17 0,000 0,07651294 0,104894 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,07651294 0,10483517 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07651294 0,1047764 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,07706707 0,1054761 ! positive regulation of immune response GO:0050778 175 100 1,000 0,0797862 0,10913644 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08082793 0,11049952 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08082793 0,11043772 ! limbic system development GO:0021761 40 18 0,000 0,08082793 0,11037599 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08082793 0,11031432 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08082793 0,11025273 ! adult walking behavior GO:0007628 36 18 0,000 0,08082793 0,11019121 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08082793 0,11012975 ! heart looping GO:0001947 34 18 0,000 0,08082793 0,11006836 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08082793 0,11000704 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08082793 0,10994579 ! centrosome cycle GO:0007098 26 18 0,000 0,08082793 0,10988461 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08082793 0,10982349 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08082793 0,10976245 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08082793 0,10970147 ! glycine metabolic process GO:0006544 30 18 0,000 0,08082793 0,10964056 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08082793 0,10957971 ! response to retinoic acid GO:0032526 31 18 0,000 0,08082793 0,10951894 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08082793 0,10945823 ! DNA integration GO:0015074 32 18 0,000 0,08082793 0,10939758 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08082793 0,10933701 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08082793 0,1092765 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08082793 0,10921606 ! neural crest cell migration GO:0001755 41 18 0,000 0,08082793 0,10915569 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08082793 0,10909538 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08082793 0,10903514 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08082793 0,10897497 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,08082793 0,10891486 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,08082793 0,10885482 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08082793 0,10879484 ! detection of bacterium GO:0016045 22 18 0,000 0,08082793 0,10873493 ! nerve development GO:0021675 34 18 0,000 0,08082793 0,10867509 ! microspike assembly GO:0030035 46 18 0,000 0,08082793 0,10861531 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08082793 0,1085556 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08512289 0,11426111 ! positive regulation of translation GO:0045727 31 19 0,000 0,08512289 0,11419836 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08512289 0,11413568 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,08512289 0,11407307 ! neuron maturation GO:0042551 46 19 0,000 0,08512289 0,11401053 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,08512289 0,11394806 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,08512289 0,11388566 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08512289 0,11382333 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08512289 0,11376106 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08512289 0,11369886 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08512289 0,11363673 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08512289 0,11357467 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08512289 0,11351267 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08512289 0,11345074 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,08512289 0,11338888 ! cerebral cortex development GO:0021987 40 19 0,000 0,08512289 0,11332709 ! pigmentation during development GO:0048066 42 19 0,000 0,08512289 0,11326537 ! response to vitamin A GO:0033189 32 19 0,000 0,08512289 0,11320371 ! heme metabolic process GO:0042168 40 19 0,000 0,08512289 0,11314212 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,08512289 0,1130806 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,08512289 0,11301914 ! response to fungus GO:0009620 26 19 0,000 0,08512289 0,11295775 ! peptide cross-linking GO:0018149 39 19 0,000 0,08512289 0,11289642 ! heart process GO:0003015 32 19 0,000 0,08512289 0,11283517 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,08512289 0,11277398 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08512289 0,11271285 ! visual learning GO:0008542 38 19 0,000 0,08512289 0,1126518 ! cellular pigmentation GO:0033059 37 19 0,000 0,08512289 0,1125908 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08512289 0,11252988 ! vitamin transport GO:0051180 31 19 0,000 0,08512289 0,11246902 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08512289 0,11240822 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08512289 0,1123475 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,08512289 0,11228683 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08512289 0,11222624 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08512289 0,1121657 ! cilium assembly GO:0042384 38 19 0,000 0,08512289 0,11210524 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08512289 0,11204484 ! protein secretion GO:0009306 45 20 0,000 0,08939789 0,11760854 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08939789 0,11754524 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08939789 0,11748201 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08939789 0,11741885 ! skin development GO:0043588 42 20 0,000 0,08939789 0,11735575 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08939789 0,11729273 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08939789 0,11722977 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08939789 0,11716688 ! response to vitamin GO:0033273 36 20 0,000 0,08939789 0,11710405 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08939789 0,11704129 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08939789 0,1169786 ! response to alkaloid GO:0043279 38 20 0,000 0,08939789 0,11691598 ! retinoid metabolic process GO:0001523 34 20 0,000 0,08939789 0,11685343 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,08939789 0,11679094 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08939789 0,11672852 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08939789 0,11666616 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,08939789 0,11660387 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,08939789 0,11654165 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08939789 0,1164795 ! peptide secretion GO:0002790 38 20 0,000 0,08939789 0,11641741 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08939789 0,11635538 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08939789 0,11629343 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08939789 0,11623154 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08939789 0,11616971 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08939789 0,11610795 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,08939789 0,11604626 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08939789 0,11598463 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08939789 0,11592307 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08939789 0,11586157 ! regulation of glucose import GO:0046324 30 20 0,000 0,08939789 0,11580014 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08939789 0,11573877 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08939789 0,11567747 ! negative regulation of translation GO:0017148 32 20 0,000 0,08939789 0,11561623 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08939789 0,11555506 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,09365304 0,12099121 ! hormone secretion GO:0046879 39 21 0,000 0,09365304 0,12092727 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09365304 0,12086338 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09365304 0,12079957 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09365304 0,12073582 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09365304 0,12067214 ! ovarian follicle development GO:0001541 39 21 0,000 0,09365304 0,12060853 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09365304 0,12054499 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09365304 0,12048151 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09365304 0,1204181 ! plasma membrane fusion GO:0045026 33 21 0,000 0,09365304 0,12035475 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09365304 0,12029148 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,09365304 0,12022826 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09365304 0,12016512 ! diencephalon development GO:0021536 36 21 0,000 0,09365304 0,12010204 ! collagen fibril organization GO:0030199 62 21 0,000 0,09365304 0,12003903 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09365304 0,11997608 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,09365304 0,1199132 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,09365304 0,11985039 ! collagen catabolic process GO:0030574 29 21 0,000 0,09365304 0,11978764 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,09365304 0,11972495 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,09365304 0,11966234 ! sperm-egg recognition GO:0035036 23 21 0,000 0,09365304 0,11959978 ! actin filament-based movement GO:0030048 47 21 0,000 0,09365304 0,1195373 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,09365304 0,11947488 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,09788843 0,12481286 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09788843 0,12474775 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09788843 0,12468271 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09788843 0,12461773 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09788843 0,12455283 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09788843 0,12448799 ! microtubule-based transport GO:0010970 59 22 0,000 0,09788843 0,12442322 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,09788843 0,12435852 ! vacuolar transport GO:0007034 41 22 0,000 0,09788843 0,12429388 ! fucose metabolic process GO:0006004 44 22 0,000 0,09788843 0,12422932 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09788843 0,12416481 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09788843 0,12410038 ! cell aging GO:0007569 48 22 0,000 0,09788843 0,12403601 ! stem cell differentiation GO:0048863 57 22 0,000 0,09788843 0,12397171 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,09788843 0,12390748 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09788843 0,12384331 ! cytolysis GO:0019835 27 22 0,000 0,09788843 0,12377921 ! renal system process GO:0003014 42 22 0,000 0,09788843 0,12371518 ! vasodilation GO:0042311 40 22 0,000 0,09788843 0,12365121 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09788843 0,1235873 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,09788843 0,12352347 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,09788843 0,1234597 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09788843 0,12339599 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09788843 0,12333235 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09788843 0,12326878 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09788843 0,12320527 ! sarcomere organization GO:0045214 32 22 0,000 0,09788843 0,12314183 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09788843 0,12307845 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09788843 0,12301514 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,09788843 0,12295189 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09788843 0,12288871 ! gut development GO:0048565 44 22 0,000 0,09788843 0,12282559 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09788843 0,12276254 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,09788843 0,12269956 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10210414 0,12791816 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10210414 0,1278526 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10210414 0,1277871 ! gluconeogenesis GO:0006094 38 23 0,000 0,10210414 0,12772167 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10210414 0,1276563 ! viral genome replication GO:0019079 44 23 0,000 0,10210414 0,12759101 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10210414 0,12752578 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10210414 0,12746061 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,10210414 0,12739551 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10210414 0,12733048 ! regeneration GO:0031099 42 23 0,000 0,10210414 0,12726552 ! axis specification GO:0009798 43 23 0,000 0,10210414 0,12720062 ! visual behavior GO:0007632 46 23 0,000 0,10210414 0,12713579 ! response to ethanol GO:0045471 47 23 0,000 0,10210414 0,12707102 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10210414 0,12700632 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,10210414 0,12694169 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10210414 0,12687712 ! peroxisome organization GO:0007031 43 23 0,000 0,10210414 0,12681262 ! lysosome organization GO:0007040 47 23 0,000 0,10210414 0,12674818 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10210414 0,12668381 ! vesicle targeting GO:0006903 49 23 0,000 0,10210414 0,1266195 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,10210414 0,12655526 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10210414 0,12649108 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10210414 0,12642697 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10210414 0,12636293 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10210414 0,12629895 ! DNA modification GO:0006304 36 23 0,000 0,10210414 0,12623503 ! fatty acid transport GO:0015908 47 23 0,000 0,10210414 0,12617118 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,10210414 0,12610739 ! hormone transport GO:0009914 41 23 0,000 0,10210414 0,12604367 ! cell-cell recognition GO:0009988 28 23 0,000 0,10210414 0,12598001 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10210414 0,12591641 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10210414 0,12585288 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10210414 0,12578942 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10630027 0,13089292 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10630027 0,13082698 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10630027 0,13076111 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10630027 0,1306953 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10630027 0,13062956 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10630027 0,13056388 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,10630027 0,13049827 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,10630027 0,13043273 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10630027 0,13036725 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10630027 0,13030184 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10630027 0,13023649 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10630027 0,13017121 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10630027 0,13010599 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10630027 0,13004084 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,10630027 0,12997576 ! pallium development GO:0021543 56 24 0,000 0,10630027 0,12991074 ! oogenesis GO:0048477 44 24 0,000 0,10630027 0,12984578 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10630027 0,12978089 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,10630027 0,12971606 ! platelet activation GO:0030168 41 24 0,000 0,10630027 0,1296513 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,10630027 0,12958661 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10630027 0,12952198 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10630027 0,12945741 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10630027 0,12939291 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10630027 0,12932847 ! regulation of amine transport GO:0051952 41 24 0,000 0,10630027 0,12926409 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,11047691 0,13427616 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,11047691 0,13420939 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,11047691 0,13414269 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,11047691 0,13407605 ! phototransduction GO:0007602 37 25 0,000 0,11047691 0,13400948 ! keratinization GO:0031424 37 25 0,000 0,11047691 0,13394297 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,11047691 0,13387653 ! vacuole organization GO:0007033 49 25 0,000 0,11047691 0,13381016 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,11047691 0,13374385 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,11047691 0,13367761 ! chromosome condensation GO:0030261 48 25 0,000 0,11047691 0,13361143 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,11047691 0,13354532 ! regulation of behavior GO:0050795 48 25 0,000 0,11047691 0,13347927 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,11047691 0,13341329 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,11047691 0,13334737 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,11047691 0,13328152 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,11047691 0,13321574 ! liver development GO:0001889 55 25 0,000 0,11047691 0,13315002 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11463414 0,13809231 ! initiation of viral infection GO:0019059 60 26 0,000 0,11463414 0,13802425 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,11463414 0,13795626 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11463414 0,13788834 ! molting cycle process GO:0022404 52 26 0,000 0,11463414 0,13782048 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11463414 0,13775269 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11463414 0,13768496 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11463414 0,1376173 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11463414 0,13754971 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11463414 0,13748219 ! digestive system process GO:0022600 49 26 0,000 0,11463414 0,13741473 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11463414 0,13734733 ! neural crest cell development GO:0014032 59 26 0,000 0,11463414 0,13728001 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11463414 0,13721274 ! negative regulation of cell development GO:0010721 83 26 0,000 0,11463414 0,13714555 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11463414 0,13707842 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11463414 0,13701136 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11463414 0,13694436 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11463414 0,13687743 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11463414 0,13681056 ! blastocyst development GO:0001824 50 26 0,000 0,11463414 0,13674376 ! telomere organization GO:0032200 46 26 0,000 0,11463414 0,13667702 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11463414 0,13661035 ! alditol metabolic process GO:0019400 44 26 0,000 0,11463414 0,13654374 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11463414 0,1364772 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11877207 0,14133471 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,11877207 0,1412659 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,11877207 0,14119716 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,11877207 0,14112848 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11877207 0,14105987 ! iron ion transport GO:0006826 65 27 0,000 0,11877207 0,14099133 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,11877207 0,14092285 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11877207 0,14085444 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,11877207 0,1407861 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,11877207 0,14071783 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11877207 0,14064962 ! response to toxin GO:0009636 49 27 0,000 0,11877207 0,14058147 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,11877207 0,14051339 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,11877207 0,14044538 ! neuron fate commitment GO:0048663 52 28 0,000 0,12289076 0,14524535 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,12289076 0,14517512 ! vesicle docking GO:0048278 55 28 0,000 0,12289076 0,14510495 ! circadian rhythm GO:0007623 56 28 0,000 0,12289076 0,14503485 ! fat cell differentiation GO:0045444 57 28 0,000 0,12289076 0,14496482 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12289076 0,14489485 ! sperm motility GO:0030317 37 28 0,000 0,12289076 0,14482496 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12289076 0,14475513 ! base-excision repair GO:0006284 41 28 0,000 0,12289076 0,14468537 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12289076 0,14461567 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,12289076 0,14454605 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12289076 0,14447649 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12289076 0,14440699 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12289076 0,14433757 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12289076 0,14426821 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12289076 0,14419891 ! lipid oxidation GO:0034440 48 28 0,000 0,12289076 0,14412969 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,12289076 0,14406053 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,12699033 0,1487949 ! translational initiation GO:0006413 66 29 0,000 0,12699033 0,14872357 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,12699033 0,14865231 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12699033 0,14858112 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,12699033 0,14850999 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,12699033 0,14843894 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,12699033 0,14836795 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,12699033 0,14829702 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,12699033 0,14822617 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,12699033 0,14815538 ! synaptogenesis GO:0007416 46 29 0,000 0,12699033 0,14808467 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,12699033 0,14801401 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12699033 0,14794343 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12699033 0,14787291 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,12699033 0,14780247 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,13107085 0,15247909 ! phenol metabolic process GO:0018958 56 30 0,000 0,13107085 0,15240651 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,13107085 0,15233401 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,13107085 0,15226157 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,13107085 0,1521892 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,13107085 0,1521169 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,13107085 0,15204467 ! acute-phase response GO:0006953 50 30 0,000 0,13107085 0,15197251 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,13107085 0,15190042 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,13107085 0,15182839 ! myofibril assembly GO:0030239 50 30 0,000 0,13107085 0,15175644 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,13107085 0,15168455 ! cell fate determination GO:0001709 64 30 0,000 0,13107085 0,15161273 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,13107085 0,15154098 ! phospholipid transport GO:0015914 65 30 0,000 0,13107085 0,15146929 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,13107085 0,15139767 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,13107085 0,15132613 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,13107085 0,15125464 ! tissue homeostasis GO:0001894 50 30 0,000 0,13107085 0,15118323 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,13513241 0,15579447 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,13513241 0,15572098 GO:0009799|determination of symmetry, ! amino sugar metabolic process GO:0006040 41 31 0,000 0,13513241 0,15564756 ! regulation of innate immune response GO:0045088 57 31 0,000 0,13513241 0,15557421 ! ovulation cycle process GO:0022602 55 31 0,000 0,13513241 0,15550093 ! peptide transport GO:0015833 60 31 0,000 0,13513241 0,15542772 ! male gonad development GO:0008584 56 31 0,000 0,13513241 0,15535457 ! iron ion homeostasis GO:0055072 60 31 0,000 0,13513241 0,1552815 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,13513241 0,1552085 ! detection of light stimulus GO:0009583 44 31 0,000 0,13513241 0,15513556 ! natural killer cell activation GO:0030101 50 31 0,000 0,13513241 0,15506269 ! cofactor catabolic process GO:0051187 54 31 0,000 0,13513241 0,15498989 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,13513241 0,15491716 ! eye morphogenesis GO:0048592 65 31 0,000 0,13513241 0,1548445 ! response to heat GO:0009408 54 31 0,000 0,13513241 0,1547719 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,1391751 0,15932744 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1391751 0,15925282 ! collagen metabolic process GO:0032963 49 32 0,000 0,1391751 0,15917826 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1391751 0,15910377 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1391751 0,15902936 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,1391751 0,15895501 ! muscle cell development GO:0055001 52 32 0,000 0,1391751 0,15888073 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,1391751 0,15880652 ! ovulation cycle GO:0042698 57 32 0,000 0,1391751 0,15873238 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1391751 0,15865831 ! gene silencing GO:0016458 71 32 0,000 0,1391751 0,15858431 ! regulation of pH GO:0006885 56 33 0,000 0,143199 0,16309332 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,143199 0,16301732 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,143199 0,16294139 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,143199 0,16286553 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,143199 0,16278975 ! response to ionizing radiation GO:0010212 74 33 0,000 0,143199 0,16271403 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,143199 0,16263838 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,143199 0,16256281 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,143199 0,1624873 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,143199 0,16241187 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,143199 0,1623365 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,14720421 0,16679958 ! glial cell differentiation GO:0010001 67 34 0,000 0,14720421 0,16672225 ! post-embryonic development GO:0009791 76 34 0,000 0,14720421 0,16664499 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,14720421 0,1665678 ! spliceosome assembly GO:0000245 75 34 0,000 0,14720421 0,16649069 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,14720421 0,16641365 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,14720421 0,16633667 ! adult locomotory behavior GO:0008344 62 34 0,000 0,14720421 0,16625977 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,15119081 0,17068352 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,15119081 0,17060469 ! negative regulation of secretion GO:0051048 68 35 0,000 0,15119081 0,17052592 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,15119081 0,17044723 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,15119081 0,17036861 ! membrane docking GO:0022406 69 35 0,000 0,15119081 0,17029006 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,15119081 0,17021159 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,15119081 0,17013319 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,15119081 0,17005486 ! ceramide metabolic process GO:0006672 72 35 0,000 0,15119081 0,1699766 ! telencephalon development GO:0021537 81 35 0,000 0,15119081 0,16989841 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,15119081 0,1698203 ! placenta development GO:0001890 53 35 0,000 0,15119081 0,16974225 ! vesicle localization GO:0051648 70 35 0,000 0,15119081 0,16966428 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,15515888 0,17403726 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,15515888 0,17395739 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,15515888 0,17387759 ! positive regulation of cell development GO:0010720 85 36 0,000 0,15515888 0,17379787 ! protein targeting to membrane GO:0006612 75 36 0,000 0,15515888 0,17371822 ! regulation of proteolysis GO:0030162 77 36 0,000 0,15515888 0,17363864 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,15515888 0,17355913 ! aerobic respiration GO:0009060 56 36 0,000 0,15515888 0,1734797 ! cytokine production GO:0001816 68 36 0,000 0,15515888 0,17340034 ! embryonic organ development GO:0048568 67 36 0,000 0,15515888 0,17332106 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,15515888 0,17324184 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,15515888 0,1731627 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,15910852 0,17748955 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,15910852 0,17740854 ! odontogenesis GO:0042476 74 37 0,000 0,15910852 0,1773276 ! actomyosin structure organization GO:0031032 68 37 0,000 0,15910852 0,17724674 ! female gonad development GO:0008585 71 37 0,000 0,15910852 0,17716596 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15910852 0,17708524 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,1630398 0,18137806 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,1630398 0,18129551 ! organic anion transport GO:0015711 82 38 0,000 0,1630398 0,18121302 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,1630398 0,18113062 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,1630398 0,18104828 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,1630398 0,18096603 ! spermatid development GO:0007286 69 38 0,000 0,1630398 0,18088385 ! pigment metabolic process GO:0042440 87 38 0,000 0,1630398 0,18080174 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,16695281 0,18505704 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,16695281 0,18497311 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,16695281 0,18488926 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,16695281 0,18480549 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,16695281 0,18472179 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,16695281 0,18463817 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,17084764 0,18886008 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,17084764 0,18877466 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,17084764 0,18868932 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,17084764 0,18860406 ! RNA export from nucleus GO:0006405 61 41 0,000 0,17472436 0,19279658 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,17472436 0,19270953 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,17472436 0,19262257 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,17472436 0,19253569 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,17472436 0,19244888 ! gliogenesis GO:0042063 91 41 0,000 0,17472436 0,19236215 ! feeding behavior GO:0007631 69 41 0,000 0,17472436 0,1922755 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,17472436 0,19218893 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,17472436 0,19210244 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,17472436 0,19201602 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,17472436 0,19192968 ! RNA modification GO:0009451 64 41 0,000 0,17472436 0,19184342 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,17858307 0,19599211 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,17858307 0,19590411 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17858307 0,19581618 ! regulation of protein secretion GO:0050708 77 42 0,000 0,17858307 0,19572833 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,17858307 0,19564056 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,17858307 0,19555287 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,18242385 0,19966911 ! regulation of tube size GO:0035150 76 43 0,000 0,18242385 0,1995797 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,18242385 0,19949036 ! glucose transport GO:0015758 66 43 0,000 0,18242385 0,1994011 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,18242385 0,19931192 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,18242385 0,19922283 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,18242385 0,19913381 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,18242385 0,19904487 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,18242385 0,19895601 ! ion transmembrane transport GO:0034220 79 43 0,000 0,18242385 0,19886723 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,18242385 0,19877853 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,18624677 0,20285371 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,18624677 0,20276331 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,18624677 0,20267299 ! hexose transport GO:0008645 68 44 0,000 0,18624677 0,20258275 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,18624677 0,2024926 ! striated muscle contraction GO:0006941 85 44 0,000 0,18624677 0,20240252 ! phagocytosis GO:0006909 105 44 0,000 0,18624677 0,20231252 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,18624677 0,20222261 ! double-strand break repair GO:0006302 85 44 0,000 0,18624677 0,20213277 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,19005193 0,2061709 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,19005193 0,20607939 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,19005193 0,20598796 ! biopolymer methylation GO:0043414 91 45 0,000 0,19005193 0,20589661 ! B cell differentiation GO:0030183 124 45 0,000 0,19005193 0,20580535 ! female gamete generation GO:0007292 71 45 0,000 0,19005193 0,20571416 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,19005193 0,20562306 ! developmental growth GO:0048589 88 45 0,000 0,19005193 0,20553203 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,1938394 0,20953524 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,1938394 0,20944257 ! glycolysis GO:0006096 71 46 0,000 0,1938394 0,20934998 ! leukocyte migration GO:0050900 75 46 0,000 0,1938394 0,20925747 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,1938394 0,20916504 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,1938394 0,20907269 ! pigmentation GO:0043473 103 46 0,000 0,1938394 0,20898043 ! cell growth GO:0016049 90 46 0,000 0,1938394 0,20888824 ! positive regulation of defense response GO:0031349 88 48 0,000 0,2013616 0,21689876 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,2013616 0,21680317 ! mitochondrial transport GO:0006839 94 48 0,000 0,2013616 0,21670766 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,2013616 0,21661224 ! male sex differentiation GO:0046661 93 48 0,000 0,2013616 0,2165169 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,2013616 0,21642164 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,2013616 0,21632647 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,2013616 0,21623138 ! methylation GO:0032259 97 48 0,000 0,2013616 0,21613638 ! response to calcium ion GO:0051592 94 49 0,000 0,2050965 0,22004864 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,2050965 0,21995204 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,2050965 0,21985553 ! JNK cascade GO:0007254 106 49 0,000 0,2050965 0,2197591 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,20881404 0,22364432 ! endocrine system development GO:0035270 109 50 0,000 0,20881404 0,22354632 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,20881404 0,2234484 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,20881404 0,22335057 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,20881404 0,22325282 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,20881404 0,22315516 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,20881404 0,22305759 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,20881404 0,2229601 ! viral infectious cycle GO:0019058 104 51 0,000 0,2125143 0,22681189 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,2125143 0,22671285 ! peptide metabolic process GO:0006518 80 51 0,000 0,2125143 0,22661389 ! response to temperature stimulus GO:0009266 84 51 0,000 0,2125143 0,22651502 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,2125143 0,22641623 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,21619735 0,23023981 ! Notch signaling pathway GO:0007219 111 52 0,000 0,21619735 0,23013949 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,21619735 0,23003925 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,21619735 0,22993911 ! excretion GO:0007588 87 52 0,000 0,21619735 0,22983904 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,21619735 0,22973907 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,21619735 0,22963918 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,21619735 0,22953938 ! amino acid activation GO:0043038 98 52 0,000 0,21619735 0,22943967 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,21986328 0,23322883 ! chromatin remodeling GO:0006338 122 53 0,000 0,21986328 0,2331276 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,21986328 0,23302646 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,21986328 0,23292541 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,21986328 0,23282445 ! cartilage development GO:0051216 99 53 0,000 0,21986328 0,23272357 ! regulation of translational initiation GO:0006446 87 54 0,000 0,22351217 0,23648343 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,22351217 0,23638105 ! neuromuscular process GO:0050905 107 54 0,000 0,22351217 0,23627877 ! membrane fusion GO:0006944 122 54 0,000 0,22351217 0,23617657 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,22351217 0,23607446 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,22351217 0,23597244 ! regulation of cell shape GO:0008360 142 54 0,000 0,22351217 0,23587051 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,22714409 0,23959975 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,22714409 0,23949634 ! cell recognition GO:0008037 98 55 0,000 0,22714409 0,23939302 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,22714409 0,23928979 ! cell maturation GO:0048469 107 55 0,000 0,22714409 0,23918665 ! glucose catabolic process GO:0006007 88 56 0,000 0,23075913 0,24288865 ! RNA elongation GO:0006354 90 56 0,000 0,23075913 0,24278405 ! chloride transport GO:0006821 102 57 0,000 0,23435736 0,24646364 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,23435736 0,24635759 ! regulation of actin filament length GO:0030832 118 58 0,000 0,23793886 0,2500149 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,23793886 0,24990741 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,23793886 0,24980002 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,23793886 0,24969271 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,24505198 0,25704679 ! regulation of endocytosis GO:0030100 104 60 0,000 0,24505198 0,25693647 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,24505198 0,25682625 ! adult behavior GO:0030534 104 60 0,000 0,24505198 0,25671612 ! positive regulation of secretion GO:0051047 110 61 0,000 0,24858375 0,26030437 ! regulation of cellular component size GO:0032535 125 61 0,000 0,24858375 0,26019284 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,24858375 0,26008141 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,24858375 0,25997008 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,24858375 0,25985884 ! regulation of heart contraction GO:0008016 123 61 0,000 0,24858375 0,25974769 ! camera-type eye development GO:0043010 126 61 0,000 0,24858375 0,25963664 ! proton transport GO:0015992 117 61 0,000 0,24858375 0,25952568 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,2520991 0,26308334 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,2520991 0,26297101 ! tRNA processing GO:0008033 102 62 0,000 0,2520991 0,26285877 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,2555981 0,26639341 ! hydrogen transport GO:0006818 121 64 0,000 0,25908083 0,26990809 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,25908083 0,26979304 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,26254736 0,27328641 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,26254736 0,27317002 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,26254736 0,27305373 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,26254736 0,27293753 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,26254736 0,27282144 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,26599777 0,27628935 ! gonad development GO:0008406 115 66 0,000 0,26599777 0,27617193 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,26943214 0,27961882 ! secondary metabolic process GO:0019748 125 67 0,000 0,26943214 0,27950009 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,26943214 0,27938145 ! hexose catabolic process GO:0019320 113 68 0,000 0,27285053 0,28280604 ! extracellular matrix organization GO:0030198 146 68 0,000 0,27285053 0,28268611 ! detection of external stimulus GO:0009581 102 68 0,000 0,27285053 0,28256627 ! adaptive immune response GO:0002250 126 68 0,000 0,27285053 0,28244654 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,27625302 0,28584758 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,27625302 0,28572656 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,27625302 0,28560564 ! developmental maturation GO:0021700 128 69 0,000 0,27625302 0,28548482 ! single fertilization GO:0007338 83 69 0,000 0,27625302 0,28536411 ! cell redox homeostasis GO:0045454 114 70 0,000 0,27963969 0,28874039 ! germ cell development GO:0007281 133 70 0,000 0,27963969 0,2886184 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,27963969 0,28849652 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,2830106 0,29185095 ! carbohydrate transport GO:0008643 114 72 0,000 0,28636583 0,29518639 ! B cell activation GO:0042113 179 72 0,000 0,28636583 0,29506189 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,28636583 0,29493749 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,28636583 0,2948132 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,28970546 0,29812571 ! acute inflammatory response GO:0002526 118 74 0,000 0,29302955 0,30141945 ! amino acid transport GO:0006865 148 74 0,000 0,29302955 0,30129259 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,29302955 0,30116584 ! reproductive structure development GO:0048608 131 75 0,000 0,29633818 0,30443826 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,29633818 0,30431029 ! eye development GO:0001654 155 75 0,000 0,29633818 0,30418243 ! rhythmic process GO:0048511 142 75 0,000 0,29633818 0,30405468 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,29963142 0,3073046 ! regulation of blood pressure GO:0008217 134 76 0,000 0,29963142 0,30717565 ! amine catabolic process GO:0009310 136 77 0,000 0,30290934 0,31040584 ! neurotransmitter transport GO:0006836 142 77 0,000 0,30290934 0,31027569 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,30290934 0,31014565 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,30290934 0,31001572 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,30617201 0,31322371 ! antigen processing and presentation GO:0019882 117 78 0,000 0,30617201 0,3130926 ! fertilization GO:0009566 99 78 0,000 0,30617201 0,3129616 ! blood coagulation GO:0007596 151 79 0,000 0,3094195 0,31614882 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,3094195 0,31601665 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,3094195 0,31588459 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,3094195 0,31575265 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,31265188 0,31891797 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,31265188 0,31878487 ! muscle cell differentiation GO:0042692 178 81 0,000 0,31586922 0,32193096 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,31586922 0,32179671 ! protein import into nucleus GO:0006606 174 82 0,000 0,31907159 0,32492367 ! exocytosis GO:0006887 153 83 0,000 0,32225906 0,32803287 ! response to drug GO:0042493 149 83 0,000 0,32225906 0,32789625 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,32225906 0,32775974 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,32225906 0,32762334 ! nuclear import GO:0051170 177 83 0,000 0,32225906 0,32748706 ! inorganic anion transport GO:0015698 156 83 0,000 0,32225906 0,32735089 ! response to metal ion GO:0010038 158 84 0,000 0,3254317 0,33043626 ! response to nutrient GO:0007584 135 84 0,000 0,3254317 0,33029898 ! digestion GO:0007586 130 84 0,000 0,3254317 0,33016181 ! hemostasis GO:0007599 165 85 0,000 0,32858958 0,33322721 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,32858958 0,33308894 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,33486132 0,33930577 ! alcohol catabolic process GO:0046164 142 87 0,000 0,33486132 0,33916509 ! nucleosome assembly GO:0006334 126 87 0,000 0,33486132 0,33902454 ! cellular respiration GO:0045333 143 88 0,000 0,33797532 0,3420355 ! amine biosynthetic process GO:0009309 146 88 0,000 0,33797532 0,34189387 ! sensory perception of smell GO:0007608 117 88 0,000 0,33797532 0,34175236 ! chromatin assembly GO:0031497 128 88 0,000 0,33797532 0,34161096 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,33797532 0,34146969 ! cellular defense response GO:0006968 123 89 0,000 0,34107482 0,34445878 ! protein localization in nucleus GO:0034504 192 89 0,000 0,34107482 0,34431644 ! response to inorganic substance GO:0010035 173 90 0,000 0,34415991 0,34728734 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,34415991 0,34714395 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,34415991 0,34700068 ! response to unfolded protein GO:0006986 139 90 0,000 0,34415991 0,34685753 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,35028706 0,35288713 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,35332927 0,3558052 ! amine transport GO:0015837 181 93 0,000 0,35332927 0,35565859 ! vitamin metabolic process GO:0006766 153 93 0,000 0,35332927 0,35551211 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,35635732 0,35841125 ! female pregnancy GO:0007565 166 94 0,000 0,35635732 0,35826376 ! sterol metabolic process GO:0016125 166 94 0,000 0,35635732 0,35811638 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,35635732 0,35796913 ! regulation of defense response GO:0031347 171 95 0,000 0,35937127 0,36084834 ! nucleosome organization GO:0034728 143 95 0,000 0,35937127 0,36070009 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,35937127 0,36055196 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,35937127 0,36040395 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,35937127 0,36025606 ! sex differentiation GO:0007548 171 96 0,000 0,3623712 0,36311437 ! response to protein stimulus GO:0051789 158 96 0,000 0,3623712 0,36296549 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,36535716 0,36580637 ! transcription initiation GO:0006352 171 97 0,000 0,36535716 0,36565651 ! forebrain development GO:0030900 210 98 0,000 0,36832922 0,36848005 ! hormone metabolic process GO:0042445 171 100 0,000 0,37423191 0,37423191