pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6252-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of locomotion GO:0040017 35 20 4,000 3,1E-07 7,13E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 4,000 3,1E-07 3,565E-04 ! regulation of chemotaxis GO:0050920 36 21 4,000 4,044E-07 3,1E-04 ! positive regulation of response to external stimulus GO:0032103 65 40 5,000 4,914E-07 2,826E-04 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 6,000 4,918E-07 2,262E-04 ! regulation of behavior GO:0050795 38 22 4,000 5,202E-07 1,994E-04 ! positive regulation of phosphorylation GO:0042327 102 70 6,000 9,143E-07 3,004E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 6,000 1,008E-06 2,898E-04 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 6,000 1,11E-06 2,836E-04 GO:0045937|positive regulation of phosphate metabolic process, ! response to steroid hormone stimulus GO:0048545 114 73 6,000 1,22E-06 2,805E-04 ! cellular response to hormone stimulus GO:0032870 109 74 6,000 1,339E-06 2,799E-04 ! regulation of ligase activity GO:0051340 114 75 6,000 1,468E-06 2,813E-04 ! gland development GO:0048732 148 77 6,000 1,756E-06 3,107E-04 ! positive regulation of protein modification process GO:0031401 107 78 6,000 1,917E-06 3,15E-04 ! endocrine pancreas development GO:0031018 19 13 3,000 2,043E-06 3,133E-04 ! leukocyte chemotaxis GO:0030595 43 31 4,000 3,18E-06 4,571E-04 GO:0060326|cell chemotaxis, ! positive regulation of chemokine production GO:0032722 7 5 2,000 4,067E-06 5,503E-04 ! negative regulation of ligase activity GO:0051352 91 61 5,000 6,251E-06 7,987E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 5,000 6,251E-06 7,567E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 5,000 6,878E-06 7,91E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 5,000 7,556E-06 8,276E-04 ! organ or tissue specific immune response GO:0002251 7 6 2,000 8,09E-06 8,458E-04 ! pancreas development GO:0031016 26 18 3,000 8,494E-06 8,494E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 8,494E-06 8,14E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 5,000 9,074E-06 8,348E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 5,000 9,074E-06 8,027E-04 ! apoptotic nuclear changes GO:0030262 24 19 3,000 1,07E-05 9,112E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,167E-05 9,583E-04 ! positive regulation of ligase activity GO:0051351 99 69 5,000 1,285E-05 1,019E-03 ! oxaloacetate metabolic process GO:0006107 9 7 2,000 1,408E-05 1,079E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,408E-05 1,045E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 2,000 1,408E-05 1,012E-03 GO:0002688|regulation of leukocyte chemotaxis, ! defense response to Gram-negative bacterium GO:0050829 9 7 2,000 1,408E-05 9,814E-04 ! response to glucocorticoid stimulus GO:0051384 33 21 3,000 1,633E-05 1,104E-03 ! leukocyte migration GO:0050900 60 43 4,000 1,676E-05 1,102E-03 ! negative regulation of transport GO:0051051 116 73 5,000 1,781E-05 1,138E-03 ! regulation of inflammatory response GO:0050727 60 44 4,000 1,88E-05 1,169E-03 ! positive regulation of defense response GO:0031349 59 45 4,000 2,102E-05 1,272E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 2,24E-05 1,321E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 2,24E-05 1,288E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,24E-05 1,257E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,24E-05 1,227E-03 ! response to UV GO:0009411 75 46 4,000 2,344E-05 1,254E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 3,000 2,388E-05 1,248E-03 ! response to corticosteroid stimulus GO:0031960 36 23 3,000 2,388E-05 1,22E-03 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 2,388E-05 1,194E-03 ! response to estrogen stimulus GO:0043627 74 47 4,000 2,608E-05 1,276E-03 ! endocrine system development GO:0035270 83 47 4,000 2,608E-05 1,25E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 5,000 3,012E-05 1,414E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,342E-05 1,537E-03 ! oocyte differentiation GO:0009994 12 9 2,000 3,342E-05 1,507E-03 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 2,000 3,342E-05 1,478E-03 ! spleen development GO:0048536 15 9 2,000 3,342E-05 1,45E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 3,372E-05 1,436E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of defense response GO:0031347 117 84 5,000 3,976E-05 1,663E-03 ! positive regulation of interleukin-6 production GO:0032755 13 10 2,000 4,749E-05 1,95E-03 ! protein sumoylation GO:0016925 12 10 2,000 4,749E-05 1,916E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 2,000 4,749E-05 1,883E-03 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 3,000 5,363E-05 2,091E-03 ! response to organic cyclic substance GO:0014070 47 28 3,000 5,363E-05 2,056E-03 ! positive regulation of cell motion GO:0051272 99 56 4,000 6,153E-05 2,32E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 6,493E-05 2,409E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 2,000 6,493E-05 2,371E-03 GO:0000725|recombinational repair, ! regulation of positive chemotaxis GO:0050926 17 11 2,000 6,493E-05 2,334E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 24 11 2,000 6,493E-05 2,298E-03 ! membrane protein proteolysis GO:0033619 18 11 2,000 6,493E-05 2,263E-03 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of leukocyte migration GO:0002685 24 11 2,000 6,493E-05 2,229E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 6,493E-05 2,196E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 6,493E-05 2,164E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of response to external stimulus GO:0032101 139 96 5,000 8,426E-05 2,769E-03 ! phosphoinositide metabolic process GO:0030384 87 60 4,000 8,59E-05 2,783E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 4,000 8,59E-05 2,744E-03 ! gland morphogenesis GO:0022612 23 12 2,000 8,611E-05 2,713E-03 ! response to gamma radiation GO:0010332 20 12 2,000 8,611E-05 2,676E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 3,000 9,203E-05 2,822E-03 ! regulation of protein stability GO:0031647 48 32 3,000 9,203E-05 2,785E-03 ! nucleus organization GO:0006997 49 33 3,000 1,041E-04 3,11E-03 ! regulation of chemokine production GO:0032642 17 13 2,000 1,113E-04 3,283E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,113E-04 3,241E-03 ! cellular pigmentation GO:0033059 24 13 2,000 1,113E-04 3,201E-03 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 3,000 1,173E-04 3,331E-03 ! epidermis morphogenesis GO:0048730 29 14 2,000 1,409E-04 3,952E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,409E-04 3,905E-03 ! hormone-mediated signaling GO:0009755 49 36 3,000 1,473E-04 4,033E-03 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 3,000 1,642E-04 4,443E-03 ! regulation of survival gene product expression GO:0045884 20 15 2,000 1,752E-04 4,685E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,752E-04 4,631E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 1,752E-04 4,578E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,752E-04 4,527E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 2,000 1,752E-04 4,477E-03 ! response to metal ion GO:0010038 103 70 4,000 1,793E-04 4,532E-03 ! regulation of T cell proliferation GO:0042129 58 38 3,000 1,824E-04 4,561E-03 ! pigmentation GO:0043473 74 38 3,000 1,824E-04 4,512E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 2,021E-04 4,946E-03 ! oogenesis GO:0048477 23 16 2,000 2,144E-04 5,191E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,144E-04 5,137E-03 ! branched chain family amino acid metabolic process GO:0009081 24 16 2,000 2,144E-04 5,084E-03 ! mitochondrion organization GO:0007005 104 73 4,000 2,186E-04 5,13E-03 ! regulation of T cell differentiation GO:0045580 59 41 3,000 2,46E-04 5,715E-03 ! response to inorganic substance GO:0010035 115 75 4,000 2,482E-04 5,708E-03 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 2,589E-04 5,897E-03 ! regulation of viral genome replication GO:0045069 24 17 2,000 2,589E-04 5,839E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,589E-04 5,782E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 2,589E-04 5,727E-03 ! regulation of JAK-STAT cascade GO:0046425 61 42 3,000 2,703E-04 5,921E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 2,963E-04 6,43E-03 ! positive regulation of anti-apoptosis GO:0045768 29 18 2,000 3,09E-04 6,643E-03 ! regulation of glucose import GO:0046324 21 18 2,000 3,09E-04 6,581E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 25 18 2,000 3,09E-04 6,521E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 3,241E-04 6,776E-03 ! induction of apoptosis by extracellular signals GO:0008624 74 44 3,000 3,241E-04 6,715E-03 ! positive regulation of cell cycle GO:0045787 77 45 3,000 3,537E-04 7,263E-03 ! regulation of cell cycle process GO:0010564 122 81 4,000 3,555E-04 7,235E-03 ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 3,65E-04 7,363E-03 ! response to alkaloid GO:0043279 32 19 2,000 3,65E-04 7,299E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 3,65E-04 7,236E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 3,65E-04 7,175E-03 ! regulation of interleukin-6 production GO:0032675 22 19 2,000 3,65E-04 7,114E-03 ! regulation of ossification GO:0030278 71 46 3,000 3,851E-04 7,443E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 4,185E-04 8,021E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! collagen fibril organization GO:0030199 45 20 2,000 4,27E-04 8,117E-03 ! positive regulation of osteoblast differentiation GO:0045669 33 20 2,000 4,27E-04 8,051E-03 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 4,443E-04 8,309E-03 ! regulation of protein localization GO:0032880 132 85 4,000 4,443E-04 8,242E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 3,000 4,539E-04 8,352E-03 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 4,539E-04 8,286E-03 ! regulation of angiogenesis GO:0045765 94 49 3,000 4,914E-04 8,9E-03 ! Wnt receptor signaling pathway GO:0016055 130 87 4,000 4,946E-04 8,888E-03 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 4,955E-04 8,834E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 4,955E-04 8,766E-03 ! cell aging GO:0007569 32 21 2,000 4,955E-04 8,699E-03 ! response to cytokine stimulus GO:0034097 47 21 2,000 4,955E-04 8,633E-03 ! positive regulation of growth GO:0045927 67 50 3,000 5,311E-04 9,184E-03 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 5,491E-04 9,424E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 5,491E-04 9,355E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 5,491E-04 9,286E-03 ! malate metabolic process GO:0006108 7 5 1,000 5,491E-04 9,218E-03 ! response to protozoan GO:0001562 9 5 1,000 5,491E-04 9,151E-03 ! parathyroid gland development GO:0060017 8 5 1,000 5,491E-04 9,085E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 5,491E-04 9,021E-03 ! regulation of retroviral genome replication GO:0045091 6 5 1,000 5,491E-04 8,957E-03 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 5,491E-04 8,894E-03 ! neutrophil mediated immunity GO:0002446 6 5 1,000 5,491E-04 8,831E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 1,000 5,491E-04 8,77E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 1,000 5,491E-04 8,71E-03 ! polyol catabolic process GO:0046174 7 5 1,000 5,491E-04 8,65E-03 GO:0019405|alditol catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 5,491E-04 8,591E-03 ! peptidyl-histidine phosphorylation GO:0018106 7 5 1,000 5,491E-04 8,533E-03 ! attachment of GPI anchor to protein GO:0016255 9 5 1,000 5,491E-04 8,476E-03 ! early endosome to late endosome transport GO:0045022 11 5 1,000 5,491E-04 8,419E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 5,491E-04 8,363E-03 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 5,491E-04 8,308E-03 ! centrosome duplication GO:0051298 5 5 1,000 5,491E-04 8,254E-03 ! response to UV-C GO:0010225 6 5 1,000 5,491E-04 8,201E-03 ! muscle cell proliferation GO:0033002 8 5 1,000 5,491E-04 8,148E-03 ! apical protein localization GO:0045176 6 5 1,000 5,491E-04 8,095E-03 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 5,491E-04 8,044E-03 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 5,491E-04 7,993E-03 ! regulation of anti-apoptosis GO:0045767 36 22 2,000 5,706E-04 8,254E-03 ! dicarboxylic acid metabolic process GO:0043648 33 22 2,000 5,706E-04 8,202E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 5,706E-04 8,151E-03 GO:0010810|regulation of cell-substrate adhesion, ! leukocyte homeostasis GO:0001776 33 22 2,000 5,706E-04 8,101E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 5,73E-04 8,085E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 5,73E-04 8,035E-03 ! regulation of protein catabolic process GO:0042176 77 51 3,000 5,73E-04 7,987E-03 ! aging GO:0007568 79 52 3,000 6,171E-04 8,551E-03 ! glycerophospholipid metabolic process GO:0006650 130 92 4,000 6,39E-04 8,8E-03 ! regulation of viral reproduction GO:0050792 32 23 2,000 6,526E-04 8,934E-03 ! regulation of bone remodeling GO:0046850 90 53 3,000 6,637E-04 9,032E-03 ! cytokine-mediated signaling pathway GO:0019221 76 54 3,000 7,126E-04 9,641E-03 ! regulation of tissue remodeling GO:0034103 91 54 3,000 7,126E-04 9,585E-03 ! regulation of binding GO:0051098 151 95 4,000 7,395E-04 9,889E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 7,417E-04 9,861E-03 ! fat cell differentiation GO:0045444 37 24 2,000 7,417E-04 9,805E-03 ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 7,417E-04 9,749E-03 ! response to light stimulus GO:0009416 153 96 4,000 7,755E-04 0,01013436 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 4,000 8,128E-04 0,01056173 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 8,196E-04 0,01059 ! prostate gland development GO:0030850 9 6 1,000 8,196E-04 0,01053084 ! male meiosis GO:0007140 7 6 1,000 8,196E-04 0,01047233 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 8,196E-04 0,01041447 ! amyloid precursor protein catabolic process GO:0042987 9 6 1,000 8,196E-04 0,01035725 ! pigment granule organization GO:0048753 11 6 1,000 8,196E-04 0,01030065 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 8,196E-04 0,01024467 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 1,000 8,196E-04 0,0101893 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 8,196E-04 0,01013452 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 8,196E-04 0,01008032 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 1,000 8,196E-04 0,0100267 ! DNA topological change GO:0006265 8 6 1,000 8,196E-04 9,974E-03 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 8,196E-04 9,921E-03 ! neutrophil homeostasis GO:0001780 6 6 1,000 8,196E-04 9,869E-03 ! salivary gland morphogenesis GO:0007435 11 6 1,000 8,196E-04 9,818E-03 ! peptidyl-histidine modification GO:0018202 9 6 1,000 8,196E-04 9,767E-03 ! blastocyst growth GO:0001832 15 6 1,000 8,196E-04 9,717E-03 ! negative regulation of B cell activation GO:0050869 9 6 1,000 8,196E-04 9,667E-03 ! regulation of chromosome organization GO:0033044 35 25 2,000 8,383E-04 9,837E-03 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 8,383E-04 9,787E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 8,748E-04 0,01016213 ! chromosome segregation GO:0007059 83 57 3,000 8,748E-04 0,01011107 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 8,748E-04 0,01006051 ! extracellular structure organization GO:0043062 156 99 4,000 8,914E-04 0,01019986 ! negative regulation of kinase activity GO:0033673 100 58 3,000 9,342E-04 0,01063723 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 2,000 9,425E-04 0,01067815 ! post-embryonic development GO:0009791 42 26 2,000 9,425E-04 0,01062581 ! negative regulation of protein modification process GO:0031400 50 26 2,000 9,425E-04 0,01057397 ! actin filament organization GO:0007015 95 59 3,000 9,964E-04 0,01112496 ! acute-phase response GO:0006953 42 27 2,000 1,054E-03 0,01171657 ! response to ionizing radiation GO:0010212 47 27 2,000 1,054E-03 0,01166024 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,054E-03 0,01160445 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 1,054E-03 0,01154919 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 2,000 1,054E-03 0,01149446 ! regulation of homeostatic process GO:0032844 105 60 3,000 1,061E-03 0,01151569 ! meiosis GO:0007126 96 61 3,000 1,129E-03 0,01219547 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 3,000 1,129E-03 0,01213848 ! extracellular matrix organization GO:0030198 103 61 3,000 1,129E-03 0,01208202 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,129E-03 0,01202609 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,142E-03 0,01210172 ! glycerol-3-phosphate metabolic process GO:0006072 9 7 1,000 1,142E-03 0,01204621 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,142E-03 0,01199121 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,142E-03 0,0119367 ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,142E-03 0,01188269 ! asymmetric protein localization GO:0008105 8 7 1,000 1,142E-03 0,01182916 ! organ growth GO:0035265 11 7 1,000 1,142E-03 0,01177612 ! behavioral fear response GO:0001662 13 7 1,000 1,142E-03 0,01172354 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 1,142E-03 0,01167144 ! response to UV-B GO:0010224 11 7 1,000 1,142E-03 0,0116198 ! cardiac muscle cell differentiation GO:0055007 12 7 1,000 1,142E-03 0,01156861 ! B cell lineage commitment GO:0002326 17 7 1,000 1,142E-03 0,01151787 ! T cell lineage commitment GO:0002360 12 7 1,000 1,142E-03 0,01146757 ! peptidyl-threonine modification GO:0018210 18 7 1,000 1,142E-03 0,01141771 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,142E-03 0,01136829 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,142E-03 0,01131928 ! cell junction assembly GO:0034329 56 28 2,000 1,175E-03 0,01159471 ! positive regulation of multicellular organism growth GO:0040018 38 28 2,000 1,175E-03 0,01154516 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,175E-03 0,01149603 ! regulation of B cell activation GO:0050864 42 28 2,000 1,175E-03 0,01144732 ! negative regulation of cell growth GO:0030308 106 62 3,000 1,2E-03 0,01164907 ! meiotic cell cycle GO:0051321 97 62 3,000 1,2E-03 0,01160013 ! regulation of transcription factor activity GO:0051090 97 63 3,000 1,274E-03 0,01226391 GO:0090046|regulation of transcription regulator activity, ! tissue homeostasis GO:0001894 42 29 2,000 1,303E-03 0,01248697 GO:0048871|multicellular organismal homeostasis, ! negative regulation of cell size GO:0045792 108 64 3,000 1,352E-03 0,01289845 ! reproductive structure development GO:0048608 90 65 3,000 1,432E-03 0,01360888 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,44E-03 0,01362851 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,515E-03 0,01427973 ! succinate metabolic process GO:0006105 14 8 1,000 1,515E-03 0,01422145 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,515E-03 0,01416364 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,515E-03 0,01410629 ! amyloid precursor protein metabolic process GO:0042982 12 8 1,000 1,515E-03 0,01404941 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 1,000 1,515E-03 0,01399299 ! L-phenylalanine metabolic process GO:0006558 8 8 1,000 1,515E-03 0,01393702 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 12 8 1,000 1,515E-03 0,01388149 ! multicellular organism growth GO:0035264 14 8 1,000 1,515E-03 0,01382641 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 1,000 1,515E-03 0,01377176 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 1,000 1,515E-03 0,01371754 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,515E-03 0,01366374 ! myeloid cell homeostasis GO:0002262 8 8 1,000 1,515E-03 0,01361037 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,515E-03 0,01355741 ! mitochondrion localization GO:0051646 12 8 1,000 1,515E-03 0,01350486 ! mammary gland development GO:0030879 57 31 2,000 1,585E-03 0,01407952 ! meiosis I GO:0007127 52 32 2,000 1,74E-03 0,01539206 ! regulation of catabolic process GO:0009894 106 70 3,000 1,884E-03 0,01660384 ! cell junction organization GO:0034330 63 33 2,000 1,904E-03 0,01671062 ! cytokinesis GO:0000910 52 33 2,000 1,904E-03 0,01664708 ! female gonad development GO:0008585 49 33 2,000 1,904E-03 0,01658402 ! negative regulation of DNA binding GO:0043392 54 33 2,000 1,904E-03 0,01652144 ! artery development GO:0060840 19 9 1,000 1,938E-03 0,01675862 GO:0048844|artery morphogenesis, ! T cell selection GO:0045058 18 9 1,000 1,938E-03 0,01669585 ! positive regulation of survival gene product expression GO:0045885 13 9 1,000 1,938E-03 0,01663355 ! myeloid leukocyte mediated immunity GO:0002444 11 9 1,000 1,938E-03 0,01657172 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,938E-03 0,01651034 GO:0006600|creatine metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 1,938E-03 0,01644942 ! receptor clustering GO:0043113 15 9 1,000 1,938E-03 0,01638894 ! motor axon guidance GO:0008045 14 9 1,000 1,938E-03 0,01632891 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,938E-03 0,01626932 ! DNA ligation GO:0006266 14 9 1,000 1,938E-03 0,01621015 ! postreplication repair GO:0006301 11 9 1,000 1,938E-03 0,01615142 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 1,938E-03 0,01609311 ! detection of calcium ion GO:0005513 13 9 1,000 1,938E-03 0,01603522 ! defense response to Gram-positive bacterium GO:0050830 10 9 1,000 1,938E-03 0,01597775 ! response to nicotine GO:0035094 16 9 1,000 1,938E-03 0,01592069 ! phosphoinositide-mediated signaling GO:0048015 109 71 3,000 1,985E-03 0,0162491 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 2,076E-03 0,01693534 ! female gamete generation GO:0007292 43 34 2,000 2,076E-03 0,01687549 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,076E-03 0,01681607 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 2,259E-03 0,01822841 ! protein homooligomerization GO:0051260 52 35 2,000 2,259E-03 0,01816468 ! regulation of B cell proliferation GO:0030888 15 10 1,000 2,411E-03 0,01932034 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,411E-03 0,01925325 ! regulation of cell projection assembly GO:0060491 20 10 1,000 2,411E-03 0,01918663 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,411E-03 0,01912047 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,411E-03 0,01905476 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,411E-03 0,01898951 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 2,411E-03 0,0189247 ! response to X-ray GO:0010165 16 10 1,000 2,411E-03 0,01886033 ! B cell proliferation GO:0042100 14 10 1,000 2,411E-03 0,0187964 ! fear response GO:0042596 16 10 1,000 2,411E-03 0,01873289 ! negative regulation of ossification GO:0030279 19 10 1,000 2,411E-03 0,01866982 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 2,411E-03 0,01860717 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,411E-03 0,01854494 ! DNA methylation GO:0006306 15 10 1,000 2,411E-03 0,01848312 GO:0006305|DNA alkylation, ! salivary gland development GO:0007431 22 10 1,000 2,411E-03 0,01842172 ! positive regulation of acute inflammatory response GO:0002675 14 10 1,000 2,411E-03 0,01836072 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 2,411E-03 0,01830012 ! cardiac cell differentiation GO:0035051 16 10 1,000 2,411E-03 0,01823992 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 2,411E-03 0,01818012 ! negative regulation of growth GO:0045926 123 75 3,000 2,427E-03 0,0182417 ! response to nutrient GO:0007584 104 75 3,000 2,427E-03 0,01818229 ! response to reactive oxygen species GO:0000302 55 36 2,000 2,451E-03 0,01830059 ! cellular amide metabolic process GO:0043603 52 36 2,000 2,451E-03 0,01824137 ! negative regulation of binding GO:0051100 58 36 2,000 2,451E-03 0,01818252 ! development of primary female sexual characteristics GO:0046545 52 36 2,000 2,451E-03 0,01812406 GO:0046660|female sex differentiation, ! regulation of protein transport GO:0051223 114 76 3,000 2,547E-03 0,01877669 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 3,000 2,671E-03 0,01962924 ! sex differentiation GO:0007548 105 77 3,000 2,671E-03 0,01956673 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 2,000 2,864E-03 0,02091285 ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,932E-03 0,02134163 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 2,932E-03 0,02127431 ! regulation of mRNA processing GO:0050684 18 11 1,000 2,932E-03 0,02120741 ! cellular carbohydrate catabolic process GO:0044275 13 11 1,000 2,932E-03 0,02114093 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 2,932E-03 0,02107486 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 2,932E-03 0,02100921 ! T cell homeostasis GO:0043029 20 11 1,000 2,932E-03 0,02094396 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 2,932E-03 0,02087912 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 2,932E-03 0,02081468 ! digestive tract morphogenesis GO:0048546 15 11 1,000 2,932E-03 0,02075063 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! germ cell migration GO:0008354 18 11 1,000 2,932E-03 0,02068698 ! developmental growth GO:0048589 62 39 2,000 3,086E-03 0,02170571 ! response to protein stimulus GO:0051789 111 81 3,000 3,21E-03 0,02250631 ! response to calcium ion GO:0051592 58 40 2,000 3,318E-03 0,02319642 ! double-strand break repair GO:0006302 67 40 2,000 3,318E-03 0,02312613 ! positive regulation of protein transport GO:0051222 55 40 2,000 3,318E-03 0,02305626 ! palate development GO:0060021 15 12 1,000 3,501E-03 0,02425644 ! positive regulation of cell growth GO:0030307 16 12 1,000 3,501E-03 0,0241836 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 3,501E-03 0,02411119 ! glycoprotein catabolic process GO:0006516 19 12 1,000 3,501E-03 0,02403922 ! tyrosine metabolic process GO:0006570 14 12 1,000 3,501E-03 0,02396767 ! regulation of cell adhesion GO:0030155 159 83 3,000 3,505E-03 0,02391868 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 3,814E-03 0,02595142 ! cellular component disassembly GO:0022411 64 42 2,000 3,814E-03 0,02587487 ! icosanoid metabolic process GO:0006690 61 42 2,000 3,814E-03 0,02579876 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 3,818E-03 0,02574881 ! cell cycle arrest GO:0007050 150 86 3,000 3,981E-03 0,02677204 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 3,981E-03 0,02669398 ! activation of caspase activity GO:0006919 65 43 2,000 4,078E-03 0,02726259 ! DNA-dependent DNA replication GO:0006261 59 43 2,000 4,078E-03 0,02718357 ! response to insulin stimulus GO:0032868 63 43 2,000 4,078E-03 0,027105 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 1,000 4,118E-03 0,02729335 ! NAD metabolic process GO:0019674 21 13 1,000 4,118E-03 0,02721492 ! exocrine system development GO:0035272 27 13 1,000 4,118E-03 0,02713694 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 4,118E-03 0,02705941 ! regulation of exocytosis GO:0017157 17 13 1,000 4,118E-03 0,02698231 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 4,118E-03 0,02690566 ! regulation of acute inflammatory response GO:0002673 19 13 1,000 4,118E-03 0,02682944 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 4,118E-03 0,02675365 ! lymphocyte homeostasis GO:0002260 24 13 1,000 4,118E-03 0,02667829 ! interphase GO:0051325 159 88 3,000 4,322E-03 0,02792072 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 2,000 4,352E-03 0,02803924 ! reproductive developmental process GO:0003006 127 89 3,000 4,499E-03 0,02890532 ! regulation of T cell activation GO:0050863 128 89 3,000 4,499E-03 0,02882481 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 4,638E-03 0,0296303 ! protein modification by small protein conjugation GO:0032446 140 90 3,000 4,682E-03 0,02982713 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 4,781E-03 0,0303736 ! regulation of S phase GO:0033261 18 14 1,000 4,781E-03 0,03028992 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,781E-03 0,03020671 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 4,781E-03 0,03012395 ! activation of MAPKK activity GO:0000186 21 14 1,000 4,781E-03 0,03004165 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 4,781E-03 0,02995979 GO:0060675|ureteric bud morphogenesis, ! DNA unwinding during replication GO:0006268 21 14 1,000 4,781E-03 0,02987838 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 4,781E-03 0,0297974 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 4,781E-03 0,02971687 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 4,781E-03 0,02963677 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 4,781E-03 0,0295571 ! peptide hormone secretion GO:0030072 23 14 1,000 4,781E-03 0,02947786 ! unsaturated fatty acid metabolic process GO:0033559 66 46 2,000 4,934E-03 0,03034577 ! negative regulation of immune system process GO:0002683 73 47 2,000 5,242E-03 0,03215335 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 5,258E-03 0,0321659 ! response to oxidative stress GO:0006979 141 94 3,000 5,461E-03 0,03331529 ! positive regulation of cell size GO:0045793 20 15 1,000 5,489E-03 0,03339903 ! metencephalon development GO:0022037 19 15 1,000 5,489E-03 0,03331091 ! negative regulation of hormone secretion GO:0046888 20 15 1,000 5,489E-03 0,03322325 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 5,489E-03 0,03313605 ! skin development GO:0043588 25 15 1,000 5,489E-03 0,0330493 ! lipid phosphorylation GO:0046834 23 15 1,000 5,489E-03 0,03296301 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 5,489E-03 0,03287717 ! centrosome cycle GO:0007098 16 15 1,000 5,489E-03 0,03279178 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 5,489E-03 0,03270682 ! peptide secretion GO:0002790 27 15 1,000 5,489E-03 0,03262231 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 5,489E-03 0,03253823 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 5,489E-03 0,03245459 ! positive regulation of caspase activity GO:0043280 72 48 2,000 5,562E-03 0,03279933 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 5,562E-03 0,03271544 ! regulation of DNA replication GO:0006275 75 48 2,000 5,562E-03 0,03263198 ! positive regulation of cytokine production GO:0001819 73 48 2,000 5,562E-03 0,03254895 ! protein modification by small protein conjugation or removal GO:0070647 148 96 3,000 5,881E-03 0,03433114 ! regulation of intracellular transport GO:0032386 78 49 2,000 5,892E-03 0,03430954 ! germ cell development GO:0007281 68 49 2,000 5,892E-03 0,0342229 ! cartilage development GO:0051216 70 49 2,000 5,892E-03 0,0341367 ! ear development GO:0043583 72 50 2,000 6,234E-03 0,0360285 ! regulation of multicellular organism growth GO:0040014 65 50 2,000 6,234E-03 0,0359382 ! hormone secretion GO:0046879 25 16 1,000 6,243E-03 0,03589483 ! cellular response to unfolded protein GO:0034620 19 16 1,000 6,243E-03 0,03580531 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of protein binding GO:0043393 27 16 1,000 6,243E-03 0,03571624 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 6,243E-03 0,03562762 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 6,243E-03 0,03553943 ! nucleotide-excision repair GO:0006289 64 52 2,000 6,954E-03 0,03949144 ! glycerol metabolic process GO:0006071 20 17 1,000 7,04E-03 0,03988402 ! signal complex assembly GO:0007172 29 17 1,000 7,04E-03 0,03978603 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 7,04E-03 0,03968851 ! DNA duplex unwinding GO:0032508 25 17 1,000 7,04E-03 0,03959147 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 26 17 1,000 7,04E-03 0,03949491 ! neuromuscular junction development GO:0007528 23 17 1,000 7,04E-03 0,03939881 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 7,04E-03 0,03930319 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 1,000 7,04E-03 0,03920802 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 7,04E-03 0,03911331 ! peptidyl-serine modification GO:0018209 27 17 1,000 7,04E-03 0,03901907 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 7,04E-03 0,03892527 ! aromatic compound catabolic process GO:0019439 22 17 1,000 7,04E-03 0,03883192 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 7,04E-03 0,03873902 ! skeletal system morphogenesis GO:0048705 78 53 2,000 7,331E-03 0,04024365 ! kidney development GO:0001822 90 53 2,000 7,331E-03 0,04014784 ! regulation of mitosis GO:0007088 84 54 2,000 7,721E-03 0,04217949 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 2,000 7,721E-03 0,04207954 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 7,882E-03 0,04285622 ! positive regulation of translation GO:0045727 28 18 1,000 7,882E-03 0,04275514 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 7,882E-03 0,04265454 ! response to retinoic acid GO:0032526 25 18 1,000 7,882E-03 0,04255441 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 7,882E-03 0,04245476 ! prostaglandin metabolic process GO:0006693 31 18 1,000 7,882E-03 0,04235556 GO:0006692|prostanoid metabolic process, ! detection of chemical stimulus GO:0009593 26 18 1,000 7,882E-03 0,04225683 ! hormone transport GO:0009914 27 18 1,000 7,882E-03 0,04215856 ! gut development GO:0048565 26 18 1,000 7,882E-03 0,04206074 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 7,882E-03 0,04196338 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 8,535E-03 0,04533841 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 8,766E-03 0,04645657 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 8,766E-03 0,04634977 ! regeneration GO:0031099 32 19 1,000 8,766E-03 0,04624347 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 8,766E-03 0,04613765 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 8,766E-03 0,04603231 ! response to vitamin A GO:0033189 26 19 1,000 8,766E-03 0,04592745 ! renal system process GO:0003014 35 19 1,000 8,766E-03 0,04582307 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 8,766E-03 0,04571917 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 8,766E-03 0,04561573 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 8,766E-03 0,04551276 ! leukotriene biosynthetic process GO:0019370 26 19 1,000 8,766E-03 0,04541025 GO:0043450|alkene biosynthetic process, ! protein stabilization GO:0050821 26 19 1,000 8,766E-03 0,04530821 ! secondary metabolic process GO:0019748 84 57 2,000 8,961E-03 0,04621164 ! gonad development GO:0008406 79 57 2,000 8,961E-03 0,04610825 ! response to vitamin GO:0033273 29 20 1,000 9,693E-03 0,04976175 ! response to ethanol GO:0045471 37 20 1,000 9,693E-03 0,04965092 ! multicellular organismal response to stress GO:0033555 32 20 1,000 9,693E-03 0,04954058 ! chromosome condensation GO:0030261 31 20 1,000 9,693E-03 0,04943074 ! DNA modification GO:0006304 28 20 1,000 9,693E-03 0,04932138 ! positive regulation of B cell activation GO:0050871 31 20 1,000 9,693E-03 0,0492125 ! alditol metabolic process GO:0019400 24 20 1,000 9,693E-03 0,0491041 ! activation of MAPK activity GO:0000187 84 59 2,000 9,849E-03 0,04978614 ! regulation of heart contraction GO:0008016 91 60 2,000 0,0103115 0,05200976 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 0,01066085 0,05365419 ! gluconeogenesis GO:0006094 25 21 1,000 0,01066085 0,05353704 ! ovarian follicle development GO:0001541 30 21 1,000 0,01066085 0,0534204 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01066085 0,05330427 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 0,01066085 0,05318864 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 0,01066085 0,05307351 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 0,01066085 0,05295888 GO:0060415|muscle tissue morphogenesis, ! leukotriene metabolic process GO:0006691 28 21 1,000 0,01066085 0,05284475 ! platelet activation GO:0030168 28 21 1,000 0,01066085 0,0527311 ! positive regulation of protein secretion GO:0050714 26 21 1,000 0,01066085 0,05261795 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 0,01066085 0,05250528 GO:0006099|tricarboxylic acid cycle, ! cell-matrix adhesion GO:0007160 114 61 2,000 0,01078644 0,05301026 ! homeostasis of number of cells GO:0048872 84 61 2,000 0,01078644 0,05289723 ! fatty acid biosynthetic process GO:0006633 92 61 2,000 0,01078644 0,05278468 ! organelle localization GO:0051640 96 62 2,000 0,01127386 0,05505283 ! molting cycle process GO:0022404 40 22 1,000 0,01166988 0,05686595 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! cellular alkene metabolic process GO:0043449 29 22 1,000 0,01166988 0,05674572 ! blastocyst development GO:0001824 37 22 1,000 0,01166988 0,05662601 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 0,01166988 0,05650679 ! microtubule organizing center organization GO:0031023 28 22 1,000 0,01166988 0,05638808 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 0,01166988 0,05626987 ! ureteric bud development GO:0001657 32 22 1,000 0,01166988 0,05615215 ! coenzyme catabolic process GO:0009109 33 22 1,000 0,01166988 0,05603492 ! neuron fate commitment GO:0048663 32 23 1,000 0,01271915 0,06094592 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01271915 0,06081921 ! myelination GO:0042552 35 23 1,000 0,01271915 0,06069303 ! acetyl-CoA metabolic process GO:0006084 33 23 1,000 0,01271915 0,06056737 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01271915 0,06044223 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,01271915 0,06031761 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 0,01271915 0,0601935 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01271915 0,0600699 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01271915 0,0599468 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 0,01271915 0,05982421 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,01271915 0,05970212 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01271915 0,05958053 ! negative regulation of catabolic process GO:0009895 34 23 1,000 0,01271915 0,05945943 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 0,01271915 0,05933882 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01281163 0,05964928 ! defense response to bacterium GO:0042742 73 65 2,000 0,01281163 0,05952878 ! protein oligomerization GO:0051259 100 65 2,000 0,01281163 0,05940876 ! cell-substrate adhesion GO:0031589 121 66 2,000 0,01334954 0,06177854 ! positive regulation of cell projection organization GO:0031346 39 24 1,000 0,013808 0,0637719 ! pyruvate metabolic process GO:0006090 29 24 1,000 0,013808 0,0636441 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,013808 0,06351682 ! receptor metabolic process GO:0043112 37 24 1,000 0,013808 0,06339004 ! response to toxin GO:0009636 38 24 1,000 0,013808 0,06326376 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,013808 0,06313799 ! base-excision repair GO:0006284 31 24 1,000 0,013808 0,06301271 ! neurotransmitter secretion GO:0007269 32 24 1,000 0,013808 0,06288794 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01390018 0,06318264 ! acute inflammatory response GO:0002526 92 68 2,000 0,01446359 0,06561394 ! development of primary sexual characteristics GO:0045137 92 68 2,000 0,01446359 0,06548477 ! peptide transport GO:0015833 43 25 1,000 0,0149358 0,06748988 ! male gonad development GO:0008584 33 25 1,000 0,0149358 0,06735755 ! iron ion homeostasis GO:0055072 39 25 1,000 0,0149358 0,06722574 ! response to estradiol stimulus GO:0032355 34 25 1,000 0,0149358 0,06709443 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,0149358 0,06696365 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,0149358 0,06683337 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 0,0149358 0,06670359 ! leukocyte proliferation GO:0070661 39 25 1,000 0,0149358 0,06657432 GO:0032943|mononuclear cell proliferation, ! activation of protein kinase activity GO:0032147 102 69 2,000 0,01503981 0,06690826 ! response to drug GO:0042493 108 69 2,000 0,01503981 0,0667791 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 0,01562887 0,0692609 ! humoral immune response GO:0006959 86 70 2,000 0,01562887 0,0691277 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01610192 0,07108332 ! nicotinamide metabolic process GO:0006769 39 26 1,000 0,01610192 0,07094714 GO:0046496|nicotinamide nucleotide metabolic process, ! regulation of peptidase activity GO:0052547 106 72 2,000 0,01684562 0,07408207 ! alkaloid metabolic process GO:0009820 40 27 1,000 0,01730571 0,07596018 ! GPI anchor biosynthetic process GO:0006506 37 27 1,000 0,01730571 0,07581549 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 1,000 0,01730571 0,07567136 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,01730571 0,07552777 ! cofactor catabolic process GO:0051187 45 27 1,000 0,01730571 0,07538472 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,01730571 0,07524222 ! regulation of blood pressure GO:0008217 107 73 2,000 0,01747335 0,07582776 ! icosanoid biosynthetic process GO:0046456 42 28 1,000 0,01854657 0,08033352 ! GPI anchor metabolic process GO:0006505 40 28 1,000 0,01854657 0,08018252 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01854657 0,08003208 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01854657 0,07988221 GO:0008366|axon ensheathment, ! pyridine nucleotide metabolic process GO:0019362 41 28 1,000 0,01854657 0,0797329 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01854657 0,07958414 ! blood coagulation GO:0007596 116 75 2,000 0,01876766 0,08038289 GO:0050817|coagulation, ! response to unfolded protein GO:0006986 99 76 2,000 0,01943426 0,08308325 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,01982387 0,08459164 ! regulation of innate immune response GO:0045088 38 29 1,000 0,01982387 0,08443499 ! ovulation cycle process GO:0022602 41 29 1,000 0,01982387 0,08427892 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 0,01982387 0,08412342 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01982387 0,0839685 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01982387 0,08381415 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 0,02113701 0,08920206 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 0,02113701 0,08903868 ! spindle organization GO:0007051 37 30 1,000 0,02113701 0,08887591 ! ovulation cycle GO:0042698 43 30 1,000 0,02113701 0,08871373 ! hindbrain development GO:0030902 45 30 1,000 0,02113701 0,08855213 ! response to heat GO:0009408 41 30 1,000 0,02113701 0,08839113 ! alcohol catabolic process GO:0046164 104 80 2,000 0,02223055 0,09279538 ! negative regulation of secretion GO:0051048 49 31 1,000 0,02248539 0,09368913 ! odontogenesis GO:0042476 50 31 1,000 0,02248539 0,09351971 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02248539 0,0933509 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,02248539 0,0931827 ! metanephros development GO:0001656 58 31 1,000 0,02248539 0,09301511 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 1,000 0,02248539 0,09284811 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02248539 0,09268172 ! hemostasis GO:0007599 125 81 2,000 0,02296212 0,09447742 ! vitamin metabolic process GO:0006766 103 81 2,000 0,02296212 0,09430871 ! detection of stimulus GO:0051606 108 82 2,000 0,0237067 0,09719324 ! regulation of muscle development GO:0048634 48 32 1,000 0,02386842 0,09768214 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,02386842 0,09750864 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02386842 0,09733575 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02386842 0,09716347 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,02386842 0,09699181 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,02386842 0,09682075 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,02523485 0,10218338 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,02528551 0,10220855 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02528551 0,10202924 ! phosphoinositide biosynthetic process GO:0046489 47 33 1,000 0,02528551 0,10185055 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02528551 0,10167249 ! sister chromatid segregation GO:0000819 46 33 1,000 0,02528551 0,10149505 ! ear morphogenesis GO:0042471 42 33 1,000 0,02528551 0,10131823 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 0,02528551 0,10114203 ! positive regulation of cell development GO:0010720 54 33 1,000 0,02528551 0,10096643 ! regulation of proteolysis GO:0030162 50 33 1,000 0,02528551 0,10079145 ! transcription initiation GO:0006352 118 85 2,000 0,02601841 0,10353347 ! regulation of membrane potential GO:0042391 128 85 2,000 0,02601841 0,10335466 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 0,02601841 0,10317646 ! mRNA catabolic process GO:0006402 48 34 1,000 0,02673607 0,10583988 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02673607 0,10565803 ! polyol metabolic process GO:0019751 44 34 1,000 0,02673607 0,1054768 ! aerobic respiration GO:0009060 47 34 1,000 0,02673607 0,10529618 ! Notch signaling pathway GO:0007219 56 35 1,000 0,02821955 0,11094866 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,02821955 0,11075932 ! maintenance of protein location GO:0045185 65 35 1,000 0,02821955 0,11057064 ! Rho protein signal transduction GO:0007266 51 35 1,000 0,02821955 0,11038259 ! pigment metabolic process GO:0042440 61 35 1,000 0,02821955 0,11019518 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02821955 0,11000841 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! anatomical structure homeostasis GO:0060249 136 88 2,000 0,0284469 0,11070707 ! protein processing GO:0016485 114 88 2,000 0,0284469 0,11052006 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02973536 0,11533109 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 1,000 0,02973536 0,11513693 ! response to virus GO:0009615 122 91 2,000 0,03099178 0,11980018 ! regulation of protein secretion GO:0050708 51 37 1,000 0,03128296 0,12072284 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 1,000 0,03128296 0,12052062 ! cell fate commitment GO:0045165 141 92 2,000 0,03186585 0,12256097 ! DNA recombination GO:0006310 146 92 2,000 0,03186585 0,12235636 ! carbohydrate catabolic process GO:0016052 121 93 2,000 0,03275277 0,12555227 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,03286178 0,12576057 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,03286178 0,12555166 ! mesenchymal cell development GO:0014031 64 38 1,000 0,03286178 0,12534345 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 0,03286178 0,12513593 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,03447129 0,13104786 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,03447129 0,13083161 ! male sex differentiation GO:0046661 53 39 1,000 0,03447129 0,13061608 ! cell growth GO:0016049 61 39 1,000 0,03447129 0,13040125 ! synapse organization GO:0050808 55 39 1,000 0,03447129 0,13018712 ! in utero embryonic development GO:0001701 147 96 2,000 0,03549032 0,13381595 ! protein maturation GO:0051604 129 96 2,000 0,03549032 0,13359694 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,03611093 0,135711 ! T cell differentiation GO:0030217 65 40 1,000 0,03611093 0,13548961 ! B cell differentiation GO:0030183 62 40 1,000 0,03611093 0,13526895 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,03611093 0,135049 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,03611093 0,13482976 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03691395 0,13760467 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03691395 0,137382 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03691395 0,13716006 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03691395 0,13693884 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03691395 0,13671832 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03691395 0,13649852 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03691395 0,13627942 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03691395 0,13606102 ! sleep GO:0030431 11 5 0,000 0,03691395 0,13584333 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03691395 0,13562632 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03691395 0,13541001 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03691395 0,13519439 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03691395 0,13497946 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03691395 0,1347652 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03691395 0,13455163 ! tongue development GO:0043586 6 5 0,000 0,03691395 0,13433873 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03691395 0,13412651 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03691395 0,13391495 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03691395 0,13370406 ! cobalt ion transport GO:0006824 9 5 0,000 0,03691395 0,13349383 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03691395 0,13328427 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03691395 0,13307536 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03691395 0,1328671 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03691395 0,1326595 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03691395 0,13245254 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03691395 0,13224623 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03691395 0,13204056 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03691395 0,13183553 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03691395 0,13163113 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03691395 0,13142737 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03691395 0,13122423 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03691395 0,13102173 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03691395 0,13081984 ! behavioral response to pain GO:0048266 7 5 0,000 0,03691395 0,13061858 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03691395 0,13041794 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03691395 0,13021791 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03691395 0,1300185 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03691395 0,12981969 ! mating behavior GO:0007617 6 5 0,000 0,03691395 0,12962149 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03691395 0,1294239 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03691395 0,12922691 ! rhythmic behavior GO:0007622 12 5 0,000 0,03691395 0,12903051 ! copulation GO:0007620 7 5 0,000 0,03691395 0,12883472 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03691395 0,12863951 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03691395 0,1284449 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03691395 0,12825087 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03691395 0,12805743 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03691395 0,12786458 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03691395 0,1276723 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03691395 0,1274806 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03691395 0,12728947 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03691395 0,12709892 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03691395 0,12690894 ! lymph vessel development GO:0001945 7 5 0,000 0,03691395 0,12671952 ! endochondral ossification GO:0001958 12 5 0,000 0,03691395 0,12653067 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03691395 0,12634238 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03691395 0,12615465 ! anagen GO:0042640 6 5 0,000 0,03691395 0,12596748 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03691395 0,12578086 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03691395 0,12559479 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03691395 0,12540927 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03691395 0,1252243 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03691395 0,12503988 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03691395 0,124856 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03691395 0,12467266 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03691395 0,12448985 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03691395 0,12430758 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03691395 0,12412585 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03691395 0,12394464 ! ovulation GO:0030728 6 5 0,000 0,03691395 0,12376396 ! microvillus organization GO:0032528 7 5 0,000 0,03691395 0,12358381 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,03691395 0,12340418 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03691395 0,12322508 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03691395 0,12304649 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03691395 0,12286842 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03691395 0,12269087 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03691395 0,12251382 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03691395 0,12233729 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03691395 0,12216126 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03691395 0,12198575 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03691395 0,12181073 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03691395 0,12163622 ! urea metabolic process GO:0019627 6 5 0,000 0,03691395 0,1214622 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03691395 0,12128868 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03691395 0,12111566 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03691395 0,12094313 ! neutrophil activation GO:0042119 5 5 0,000 0,03691395 0,12077109 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03691395 0,12059954 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03691395 0,12042848 ! response to food GO:0032094 5 5 0,000 0,03691395 0,1202579 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03691395 0,12008781 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03691395 0,11991819 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03691395 0,11974905 ! forebrain neuron development GO:0021884 7 5 0,000 0,03691395 0,11958039 ! melanosome organization GO:0032438 7 5 0,000 0,03691395 0,11941221 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03691395 0,11924449 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03691395 0,11907725 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03691395 0,11891047 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03691395 0,11874417 GO:0009251|glucan catabolic process, ! nucleoside transport GO:0015858 6 5 0,000 0,03691395 0,11857832 ! nucleoside salvage GO:0043174 7 5 0,000 0,03691395 0,11841294 GO:0006166|purine ribonucleoside salvage, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03691395 0,11824802 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03691395 0,11808356 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03691395 0,11791955 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03691395 0,117756 ! depyrimidination GO:0045008 8 5 0,000 0,03691395 0,11759291 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03691395 0,11743026 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03691395 0,11726806 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03691395 0,11710632 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03691395 0,11694501 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03691395 0,11678415 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03691395 0,11662373 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03691395 0,11646376 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03691395 0,11630422 ! monocyte differentiation GO:0030224 8 5 0,000 0,03691395 0,11614511 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03691395 0,11598645 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03691395 0,11582821 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03691395 0,11567041 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03691395 0,11551303 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03691395 0,11535609 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03691395 0,11519956 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03691395 0,11504347 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03691395 0,11488779 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03691395 0,11473254 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03691395 0,1145777 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03691395 0,11442329 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03691395 0,11426928 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03691395 0,1141157 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03691395 0,11396252 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03691395 0,11380976 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03691395 0,1136574 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03691395 0,11350545 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03691395 0,11335391 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03691395 0,11320277 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03691395 0,11305204 ! neural tube patterning GO:0021532 6 5 0,000 0,03691395 0,1129017 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03691395 0,11275176 ! histone demethylation GO:0016577 9 5 0,000 0,03691395 0,11260223 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03691395 0,11245308 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03691395 0,11230434 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03691395 0,11215598 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03691395 0,11200802 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03691395 0,11186045 ! transcription termination GO:0006353 8 5 0,000 0,03691395 0,11171326 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03691395 0,11156646 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03691395 0,11142005 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03691395 0,11127402 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03691395 0,11112838 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03691395 0,11098311 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03691395 0,11083822 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03691395 0,11069371 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03691395 0,11054958 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03691395 0,11040582 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03691395 0,11026244 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03691395 0,11011943 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03691395 0,10997679 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03691395 0,10983451 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03691395 0,10969261 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03691395 0,10955107 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03691395 0,1094099 ! glial cell migration GO:0008347 10 5 0,000 0,03691395 0,10926908 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03691395 0,10912864 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03691395 0,10898855 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03691395 0,10884882 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03691395 0,10870945 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03691395 0,10857043 ! neural plate development GO:0001840 6 5 0,000 0,03691395 0,10843177 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03691395 0,10829347 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03691395 0,10815551 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03691395 0,10801791 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03691395 0,10788066 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03691395 0,10774375 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03691395 0,1076072 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03691395 0,10747099 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03691395 0,10733512 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03691395 0,10719959 ! spindle assembly GO:0051225 5 5 0,000 0,03691395 0,10706441 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03691395 0,10692957 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03691395 0,10679507 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03691395 0,1066609 ! organ regeneration GO:0031100 7 5 0,000 0,03691395 0,10652707 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03691395 0,10639358 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03691395 0,10626042 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03691395 0,1061276 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03691395 0,1059951 GO:0055081|anion homeostasis, ! protein amino acid lipidation GO:0006497 62 41 1,000 0,03778017 0,10834713 ! glucose transport GO:0015758 52 41 1,000 0,03778017 0,1082122 ! endosome transport GO:0016197 71 41 1,000 0,03778017 0,10807761 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03778017 0,10794335 ! biopolymer methylation GO:0043414 62 41 1,000 0,03778017 0,10780943 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,03834243 0,10927829 ! regulation of body fluid levels GO:0050878 154 100 2,000 0,03931842 0,11192126 ! mitochondrial transport GO:0006839 60 42 1,000 0,0394785 0,112238 ! hexose transport GO:0008645 54 42 1,000 0,0394785 0,11209943 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,0394785 0,11196121 ! embryonic skeletal system development GO:0048706 56 42 1,000 0,0394785 0,11182333 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,0394785 0,11168578 ! regulation of cell shape GO:0008360 78 42 1,000 0,0394785 0,11154858 ! positive regulation of binding GO:0051099 59 43 1,000 0,04120537 0,1162851 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,04120537 0,11614259 ! vesicle organization GO:0016050 79 43 1,000 0,04120537 0,11600044 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,04120537 0,11585863 ! methylation GO:0032259 64 43 1,000 0,04120537 0,11571716 ! regulation of action potential GO:0001508 71 44 1,000 0,04296029 0,12049836 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,04296029 0,12035159 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,04296029 0,12020518 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,04296029 0,12005912 ! glycolysis GO:0006096 53 44 1,000 0,04296029 0,11991342 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,04296029 0,11976807 ! tRNA transcription GO:0009304 11 6 0,000 0,04413282 0,122888 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04413282 0,12273941 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04413282 0,12259117 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04413282 0,12244329 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04413282 0,12229577 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04413282 0,1221486 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04413282 0,12200179 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04413282 0,12185533 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04413282 0,12170922 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04413282 0,12156346 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04413282 0,12141805 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04413282 0,12127299 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04413282 0,12112827 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04413282 0,1209839 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04413282 0,12083987 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04413282 0,12069618 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04413282 0,12055284 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04413282 0,12040983 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04413282 0,12026717 ! neuron adhesion GO:0007158 9 6 0,000 0,04413282 0,12012484 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,04413282 0,11998285 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04413282 0,11984119 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04413282 0,11969987 ! signal peptide processing GO:0006465 8 6 0,000 0,04413282 0,11955888 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04413282 0,11941822 ! mRNA stabilization GO:0048255 15 6 0,000 0,04413282 0,1192779 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04413282 0,1191379 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04413282 0,11899823 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04413282 0,11885889 ! opsonization GO:0008228 8 6 0,000 0,04413282 0,11871987 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04413282 0,11858118 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04413282 0,11844281 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04413282 0,11830477 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04413282 0,11816704 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04413282 0,11802964 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04413282 0,11789256 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04413282 0,11775579 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04413282 0,11761934 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04413282 0,11748321 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04413282 0,11734739 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04413282 0,11721188 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04413282 0,11707669 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04413282 0,11694181 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04413282 0,11680724 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04413282 0,11667298 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04413282 0,11653902 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04413282 0,11640538 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04413282 0,11627204 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04413282 0,11613901 ! thymic T cell selection GO:0045061 12 6 0,000 0,04413282 0,11600627 ! protein lipoylation GO:0009249 10 6 0,000 0,04413282 0,11587385 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04413282 0,11574172 ! drug transport GO:0015893 6 6 0,000 0,04413282 0,1156099 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04413282 0,11547837 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04413282 0,11534715 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04413282 0,11521622 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04413282 0,11508559 ! histidine metabolic process GO:0006547 6 6 0,000 0,04413282 0,11495526 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04413282 0,11482522 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04413282 0,11469547 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04413282 0,11456602 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04413282 0,11443686 ! adenohypophysis development GO:0021984 10 6 0,000 0,04413282 0,11430798 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04413282 0,1141794 ! hyperosmotic response GO:0006972 8 6 0,000 0,04413282 0,11405111 ! microtubule nucleation GO:0007020 10 6 0,000 0,04413282 0,11392311 ! ER overload response GO:0006983 7 6 0,000 0,04413282 0,11379539 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04413282 0,11366796 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04413282 0,11354082 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04413282 0,11341396 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04413282 0,11328738 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04413282 0,11316108 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04413282 0,11303507 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04413282 0,11290933 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04413282 0,11278388 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04413282 0,1126587 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04413282 0,1125338 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04413282 0,11240918 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04413282 0,11228483 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04413282 0,11216076 ! neuron apoptosis GO:0051402 8 6 0,000 0,04413282 0,11203697 ! organic alcohol transport GO:0015850 9 6 0,000 0,04413282 0,11191344 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04413282 0,11179019 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04413282 0,11166721 ! male sex determination GO:0030238 9 6 0,000 0,04413282 0,1115445 ! carnitine transport GO:0015879 8 6 0,000 0,04413282 0,11142205 GO:0015838|betaine transport, ! macroautophagy GO:0016236 10 6 0,000 0,04413282 0,11129988 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04413282 0,11117797 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04413282 0,11105634 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04413282 0,11093496 ! parturition GO:0007567 12 6 0,000 0,04413282 0,11081385 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04413282 0,11069301 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04413282 0,11057243 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04413282 0,11045211 ! spindle checkpoint GO:0031577 14 6 0,000 0,04413282 0,11033205 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04413282 0,11021226 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04413282 0,11009272 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04413282 0,10997345 ! macrophage differentiation GO:0030225 10 6 0,000 0,04413282 0,10985443 ! astrocyte development GO:0014002 14 6 0,000 0,04413282 0,10973567 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04413282 0,10961716 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04413282 0,10949891 ! interaction with symbiont GO:0051702 8 6 0,000 0,04413282 0,10938092 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04413282 0,10926318 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04413282 0,10914569 ! eating behavior GO:0042755 6 6 0,000 0,04413282 0,10902845 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04413282 0,10891147 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04413282 0,10879474 ! response to copper ion GO:0046688 9 6 0,000 0,04413282 0,10867826 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04413282 0,10856202 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04413282 0,10844604 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04413282 0,1083303 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04413282 0,10821481 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04413282 0,10809956 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04413282 0,10798456 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04413282 0,10786981 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04413282 0,1077553 ! gas homeostasis GO:0033483 11 6 0,000 0,04413282 0,10764103 ! hair follicle maturation GO:0048820 7 6 0,000 0,04413282 0,107527 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04413282 0,10741322 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04413282 0,10729967 ! Schwann cell development GO:0014044 14 6 0,000 0,04413282 0,10718637 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04413282 0,1070733 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04413282 0,10696047 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04413282 0,10684788 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04413282 0,10673553 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04413282 0,10662341 ! histone ubiquitination GO:0016574 7 6 0,000 0,04413282 0,10651153 ! regulation of meiosis GO:0040020 10 6 0,000 0,04413282 0,10639989 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04413282 0,10628847 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04413282 0,10617729 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04413282 0,10606634 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04413282 0,10595563 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04413282 0,10584514 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04413282 0,10573489 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04413282 0,10562486 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04413282 0,10551506 ! receptor internalization GO:0031623 9 6 0,000 0,04413282 0,10540549 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04413282 0,10529615 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04413282 0,10518704 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 8 6 0,000 0,04413282 0,10507815 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04413282 0,10496948 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04413282 0,10486104 ! axonal fasciculation GO:0007413 9 6 0,000 0,04413282 0,10475283 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04413282 0,10464484 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04413282 0,10453707 ! midbrain development GO:0030901 6 6 0,000 0,04413282 0,10442952 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04413282 0,10432219 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04413282 0,10421508 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04413282 0,1041082 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04413282 0,10400153 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04413282 0,10389508 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04413282 0,10378885 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04413282 0,10368283 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04413282 0,10357703 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04413282 0,10347145 ! adult feeding behavior GO:0008343 6 6 0,000 0,04413282 0,10336608 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04413282 0,10326093 ! pigment granule transport GO:0051904 12 6 0,000 0,04413282 0,10315599 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04413282 0,10305126 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04413282 0,10294674 ! catecholamine transport GO:0051937 7 6 0,000 0,04413282 0,10284244 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04413282 0,10273835 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04413282 0,10263447 ! protein prenylation GO:0018342 10 6 0,000 0,04413282 0,1025308 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04413282 0,10242734 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04413282 0,10232408 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04413282 0,10222104 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04413282 0,1021182 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04413282 0,10201557 ! RNA catabolic process GO:0006401 64 45 1,000 0,04474273 0,10332156 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,04474273 0,10321793 ! cell maturation GO:0048469 60 45 1,000 0,04474273 0,1031145 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,04655219 0,10717722 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 0,04838818 0,11129282 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,04838818 0,11118164 ! response to temperature stimulus GO:0009266 62 48 1,000 0,05025021 0,11534479 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,05025021 0,11522979 ! heart morphogenesis GO:0003007 65 48 1,000 0,05025021 0,11511502 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,051298 0,1173984 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,051298 0,1172817 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,051298 0,11716524 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,051298 0,117049 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,051298 0,116933 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,051298 0,11681722 GO:0070193|synaptonemal complex organization, ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,051298 0,11670167 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,051298 0,11658636 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,051298 0,11647127 ! reproductive behavior GO:0019098 12 7 0,000 0,051298 0,1163564 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,051298 0,11624177 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,051298 0,11612736 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,051298 0,11601317 ! oligopeptide transport GO:0006857 11 7 0,000 0,051298 0,11589921 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,051298 0,11578547 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,051298 0,11567195 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,051298 0,11555866 ! RNA methylation GO:0001510 11 7 0,000 0,051298 0,11544559 ! pericardium development GO:0060039 8 7 0,000 0,051298 0,11533274 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,051298 0,11522011 ! fibril organization GO:0043206 13 7 0,000 0,051298 0,1151077 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,051298 0,11499551 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,051298 0,11488354 ! lipoprotein transport GO:0042953 9 7 0,000 0,051298 0,11477178 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,051298 0,11466025 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,051298 0,11454893 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,051298 0,11443782 ! estrogen metabolic process GO:0008210 14 7 0,000 0,051298 0,11432693 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,051298 0,11421626 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,051298 0,1141058 ! chemosensory behavior GO:0007635 9 7 0,000 0,051298 0,11399555 ! microtubule bundle formation GO:0001578 8 7 0,000 0,051298 0,11388551 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,051298 0,11377569 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,051298 0,11366608 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,051298 0,11355668 ! leukocyte degranulation GO:0043299 10 7 0,000 0,051298 0,11344749 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,051298 0,11333851 ! reflex GO:0060004 12 7 0,000 0,051298 0,11322974 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,051298 0,11312118 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,051298 0,11301283 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,051298 0,11290468 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,051298 0,11279674 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,051298 0,11268901 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,051298 0,11258148 ! spinal cord patterning GO:0021511 7 7 0,000 0,051298 0,11247416 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,051298 0,11236704 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,051298 0,11226013 ! adrenal gland development GO:0030325 17 7 0,000 0,051298 0,11215342 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,051298 0,11204691 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,051298 0,1119406 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,051298 0,1118345 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,051298 0,11172859 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,051298 0,11162289 ! endosome organization GO:0007032 10 7 0,000 0,051298 0,11151738 ! thyroid hormone generation GO:0006590 11 7 0,000 0,051298 0,11141208 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,051298 0,11130697 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,051298 0,11120207 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,051298 0,11109736 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,051298 0,11099284 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,051298 0,11088853 ! galactose metabolic process GO:0006012 10 7 0,000 0,051298 0,11078441 ! vesicle fusion GO:0006906 15 7 0,000 0,051298 0,11068048 ! intracellular pH reduction GO:0051452 10 7 0,000 0,051298 0,11057675 GO:0045851|pH reduction, ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,051298 0,11047321 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,051298 0,11036987 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,051298 0,11026672 ! retinol metabolic process GO:0042572 9 7 0,000 0,051298 0,11016377 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,051298 0,110061 ! rRNA modification GO:0000154 12 7 0,000 0,051298 0,10995843 ! protein heterooligomerization GO:0051291 10 7 0,000 0,051298 0,10985605 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,051298 0,10975385 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,051298 0,10965185 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,051298 0,10955004 ! intermediate filament organization GO:0045109 11 7 0,000 0,051298 0,10944842 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,051298 0,10934698 ! fibrinolysis GO:0042730 9 7 0,000 0,051298 0,10924573 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,051298 0,10914467 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,051298 0,1090438 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,051298 0,10894311 ! response to tropane GO:0014073 13 7 0,000 0,051298 0,10884261 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,051298 0,1087423 ! melanosome localization GO:0032400 10 7 0,000 0,051298 0,10864217 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,051298 0,10854222 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,051298 0,10844246 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,051298 0,10834288 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,051298 0,10824348 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,051298 0,10814427 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,051298 0,10804523 ! mast cell activation GO:0045576 9 7 0,000 0,051298 0,10794638 ! multicellular organismal aging GO:0010259 11 7 0,000 0,051298 0,10784771 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,051298 0,10774922 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,051298 0,10765091 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,051298 0,10755277 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,051298 0,10745482 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,051298 0,10735705 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,051298 0,10725945 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,051298 0,10716203 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,051298 0,10706479 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,051298 0,10696772 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,051298 0,10687083 ! regulation of lipid transport GO:0032368 13 7 0,000 0,051298 0,10677411 ! response to tumor cell GO:0002347 12 7 0,000 0,051298 0,10667757 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,051298 0,1065812 ! neuroblast proliferation GO:0007405 13 7 0,000 0,051298 0,10648501 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,051298 0,10638899 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,051298 0,10629315 ! diuresis GO:0030146 12 7 0,000 0,051298 0,10619747 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,051298 0,10610197 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,051298 0,10600664 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,051298 0,10591148 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,051298 0,1058165 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,051298 0,10572168 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,051298 0,10562703 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,051298 0,10553255 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,051298 0,10543824 ! lymph node development GO:0048535 9 7 0,000 0,051298 0,1053441 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,051298 0,10525013 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,051298 0,10515632 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,051298 0,10506268 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,051298 0,10496921 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,051298 0,10487591 ! ATP catabolic process GO:0006200 10 7 0,000 0,051298 0,10478276 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,051298 0,10468979 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,051298 0,10459698 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,051298 0,10450433 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,051298 0,10441185 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,051298 0,10431953 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,051298 0,10422738 ! muscle adaptation GO:0043500 12 7 0,000 0,051298 0,10413539 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,051298 0,10404356 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,051298 0,10395189 ! retina homeostasis GO:0001895 9 7 0,000 0,051298 0,10386038 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,051298 0,10376904 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,051298 0,10367785 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,051298 0,10358682 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,051298 0,10349596 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,051298 0,10340525 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,051298 0,10331471 ! RNA elongation GO:0006354 62 49 1,000 0,05213778 0,10491417 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,05213778 0,10482246 ! maintenance of location GO:0051235 84 49 1,000 0,05213778 0,10473091 ! regulation of actin filament length GO:0030832 72 50 1,000 0,05405042 0,10847815 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,05405042 0,10838357 ! lipid modification GO:0030258 73 50 1,000 0,05405042 0,10828916 ! positive regulation of secretion GO:0051047 71 51 1,000 0,05598764 0,11207274 ! muscle fiber development GO:0048747 74 51 1,000 0,05598764 0,11197529 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,05598764 0,111878 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,05598764 0,11178089 ! regulation of cellular component size GO:0032535 74 52 1,000 0,05794899 0,11559643 ! establishment of organelle localization GO:0051656 85 52 1,000 0,05794899 0,11549626 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05840987 0,11631402 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05840987 0,11621341 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05840987 0,11611296 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05840987 0,11601269 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05840987 0,1159126 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05840987 0,11581267 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05840987 0,11571292 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05840987 0,11561334 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05840987 0,11551393 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,05840987 0,11541469 ! phosphate transport GO:0006817 10 8 0,000 0,05840987 0,11531562 ! N-glycan processing GO:0006491 12 8 0,000 0,05840987 0,11521672 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05840987 0,11511799 ! UTP metabolic process GO:0046051 8 8 0,000 0,05840987 0,11501943 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05840987 0,11492104 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05840987 0,11482282 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05840987 0,11472476 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,05840987 0,11462688 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05840987 0,11452915 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05840987 0,1144316 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05840987 0,11433421 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05840987 0,11423699 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05840987 0,11413993 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05840987 0,11404304 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05840987 0,11394631 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05840987 0,11384974 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05840987 0,11375334 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05840987 0,11365711 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05840987 0,11356103 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05840987 0,11346512 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05840987 0,11336937 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05840987 0,11327378 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05840987 0,11317835 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05840987 0,11308308 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05840987 0,11298797 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05840987 0,11289302 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05840987 0,11279824 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,05840987 0,11270361 ! macrophage activation GO:0042116 12 8 0,000 0,05840987 0,11260914 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05840987 0,11251482 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05840987 0,11242067 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05840987 0,11232667 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05840987 0,11223283 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05840987 0,11213915 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05840987 0,11204562 ! ruffle organization GO:0031529 11 8 0,000 0,05840987 0,11195225 ! osteoblast development GO:0002076 13 8 0,000 0,05840987 0,11185903 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05840987 0,11176597 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05840987 0,11167307 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05840987 0,11158031 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05840987 0,11148772 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05840987 0,11139527 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05840987 0,11130298 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05840987 0,11121084 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05840987 0,11111886 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05840987 0,11102702 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05840987 0,11093534 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05840987 0,11084381 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05840987 0,11075243 ! segment specification GO:0007379 10 8 0,000 0,05840987 0,1106612 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,05840987 0,11057012 ! cellular extravasation GO:0045123 11 8 0,000 0,05840987 0,11047919 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05840987 0,11038841 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05840987 0,11029778 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05840987 0,1102073 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05840987 0,11011697 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05840987 0,11002678 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05840987 0,10993674 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05840987 0,10984685 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05840987 0,10975711 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05840987 0,10966751 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05840987 0,10957806 ! icosanoid secretion GO:0032309 12 8 0,000 0,05840987 0,10948875 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05840987 0,10939959 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05840987 0,10931058 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05840987 0,10922171 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05840987 0,10913298 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05840987 0,1090444 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05840987 0,10895596 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05840987 0,10886767 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05840987 0,10877951 ! sterol catabolic process GO:0016127 9 8 0,000 0,05840987 0,1086915 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05840987 0,10860364 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05840987 0,10851591 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05840987 0,10842833 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05840987 0,10834089 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05840987 0,10825358 ! prophase GO:0051324 11 8 0,000 0,05840987 0,10816642 ! S phase GO:0051320 8 8 0,000 0,05840987 0,1080794 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05840987 0,10799252 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,05840987 0,10790578 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05840987 0,10781918 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05840987 0,10773272 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05840987 0,10764639 ! hormone catabolic process GO:0042447 13 8 0,000 0,05840987 0,10756021 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05840987 0,10747416 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05840987 0,10738825 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05840987 0,10730248 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05840987 0,10721684 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05840987 0,10713134 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05840987 0,10704598 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05840987 0,10696075 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05840987 0,10687566 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05840987 0,1067907 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05840987 0,10670588 ! regulation of embryonic development GO:0045995 16 8 0,000 0,05840987 0,10662119 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05840987 0,10653664 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,05840987 0,10645222 ! glycerophospholipid biosynthetic process GO:0046474 75 53 1,000 0,059934 0,10914347 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,059934 0,10905712 ! glucose catabolic process GO:0006007 66 54 1,000 0,0619422 0,11262219 ! detection of external stimulus GO:0009581 66 54 1,000 0,0619422 0,11253323 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,0619422 0,11244441 ! water-soluble vitamin metabolic process GO:0006767 71 55 1,000 0,06397315 0,11603963 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06546883 0,11865903 ! regulation of developmental growth GO:0048638 13 9 0,000 0,06546883 0,1185656 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,06546883 0,11847231 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06546883 0,11837918 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06546883 0,11828618 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06546883 0,11819334 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06546883 0,11810064 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06546883 0,11800808 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06546883 0,11791567 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06546883 0,11782341 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,06546883 0,11773128 ! GTP metabolic process GO:0046039 9 9 0,000 0,06546883 0,11763931 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06546883 0,11754747 ! social behavior GO:0035176 14 9 0,000 0,06546883 0,11745578 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06546883 0,11736423 ! regulation of histone modification GO:0031056 11 9 0,000 0,06546883 0,11727283 ! regulation of glycolysis GO:0006110 15 9 0,000 0,06546883 0,11718157 ! response to pain GO:0048265 16 9 0,000 0,06546883 0,11709044 ! protein complex disassembly GO:0043241 17 9 0,000 0,06546883 0,11699947 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06546883 0,11690863 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06546883 0,11681793 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06546883 0,11672737 ! lung alveolus development GO:0048286 17 9 0,000 0,06546883 0,11663696 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06546883 0,11654668 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06546883 0,11645654 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06546883 0,11636655 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06546883 0,11627669 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06546883 0,11618697 ! protein targeting to ER GO:0045047 19 9 0,000 0,06546883 0,11609739 ! endoderm development GO:0007492 12 9 0,000 0,06546883 0,11600794 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06546883 0,11591864 GO:0006688|glycosphingolipid biosynthetic process, ! arginine catabolic process GO:0006527 10 9 0,000 0,06546883 0,11582947 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06546883 0,11574044 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06546883 0,11565155 ! V(D)J recombination GO:0033151 12 9 0,000 0,06546883 0,11556279 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06546883 0,11547417 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06546883 0,11538568 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06546883 0,11529733 ! mannose metabolic process GO:0006013 9 9 0,000 0,06546883 0,11520911 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06546883 0,11512103 ! epithelial cell development GO:0002064 10 9 0,000 0,06546883 0,11503309 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06546883 0,11494528 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06546883 0,1148576 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06546883 0,11477005 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06546883 0,11468264 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06546883 0,11459537 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06546883 0,11450822 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06546883 0,11442121 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06546883 0,11433433 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06546883 0,11424758 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06546883 0,11416096 ! response to amine stimulus GO:0014075 13 9 0,000 0,06546883 0,11407448 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06546883 0,11398812 ! erythrocyte development GO:0048821 11 9 0,000 0,06546883 0,1139019 ! renal water homeostasis GO:0003091 14 9 0,000 0,06546883 0,11381581 ! mRNA cleavage GO:0006379 13 9 0,000 0,06546883 0,11372984 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06546883 0,11364401 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06546883 0,1135583 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06546883 0,11347273 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06546883 0,11338728 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06546883 0,11330197 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06546883 0,11321678 ! acid secretion GO:0046717 14 9 0,000 0,06546883 0,11313171 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06546883 0,11304678 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06546883 0,11296197 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06546883 0,1128773 ! purine base metabolic process GO:0006144 18 9 0,000 0,06546883 0,11279274 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06546883 0,11270832 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06546883 0,11262402 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06546883 0,11253984 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06546883 0,1124558 ! blastocyst formation GO:0001825 12 9 0,000 0,06546883 0,11237187 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06546883 0,11228808 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06546883 0,11220441 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06546883 0,11212086 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06546883 0,11203743 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06546883 0,11195414 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06546883 0,11187096 ! prepulse inhibition GO:0060134 14 9 0,000 0,06546883 0,11178791 ! embryonic placenta development GO:0001892 12 9 0,000 0,06546883 0,11170498 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06546883 0,11162217 ! insulin secretion GO:0030073 17 9 0,000 0,06546883 0,11153949 ! sequestering of metal ion GO:0051238 11 9 0,000 0,06546883 0,11145693 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06546883 0,11137449 ! nucleus localization GO:0051647 15 9 0,000 0,06546883 0,11129217 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06546883 0,11120998 ! localization within membrane GO:0051668 15 9 0,000 0,06546883 0,11112791 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,0660264 0,11199168 ! developmental maturation GO:0021700 75 57 1,000 0,06810151 0,11542628 ! carbohydrate transport GO:0008643 74 57 1,000 0,06810151 0,11534128 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,06810151 0,11525641 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,07019803 0,11871725 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,07019803 0,11863003 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,07231554 0,12211875 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07247527 0,1222987 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07247527 0,12220904 ! neuron fate specification GO:0048665 11 10 0,000 0,07247527 0,12211951 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07247527 0,12203011 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07247527 0,12194084 ! thyroid gland development GO:0030878 19 10 0,000 0,07247527 0,1218517 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07247527 0,1217627 ! synapsis GO:0007129 13 10 0,000 0,07247527 0,12167382 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07247527 0,12158507 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07247527 0,12149645 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07247527 0,12140796 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,07247527 0,1213196 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07247527 0,12123137 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,07247527 0,12114326 ! phospholipid efflux GO:0033700 16 10 0,000 0,07247527 0,12105529 ! hippocampus development GO:0021766 19 10 0,000 0,07247527 0,12096744 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07247527 0,12087972 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07247527 0,12079212 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07247527 0,12070466 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07247527 0,12061732 ! pathogenesis GO:0009405 13 10 0,000 0,07247527 0,1205301 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07247527 0,12044301 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07247527 0,12035605 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,07247527 0,12026921 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,07247527 0,1201825 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07247527 0,12009592 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07247527 0,12000945 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07247527 0,11992312 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07247527 0,1198369 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07247527 0,11975081 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07247527 0,11966485 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07247527 0,119579 ! forebrain cell migration GO:0021885 17 10 0,000 0,07247527 0,11949328 ! lipid digestion GO:0044241 15 10 0,000 0,07247527 0,11940769 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07247527 0,11932221 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07247527 0,11923686 ! UV protection GO:0009650 14 10 0,000 0,07247527 0,11915163 ! entry into host cell GO:0030260 20 10 0,000 0,07247527 0,11906652 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07247527 0,11898154 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07247527 0,11889667 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07247527 0,11881193 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07247527 0,1187273 ! regulation of organ growth GO:0046620 11 10 0,000 0,07247527 0,1186428 ! response to dsRNA GO:0043331 18 10 0,000 0,07247527 0,11855842 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07247527 0,11847415 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07247527 0,11839001 ! embryonic axis specification GO:0000578 12 10 0,000 0,07247527 0,11830598 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07247527 0,11822208 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07247527 0,11813829 ! cranial nerve development GO:0021545 12 10 0,000 0,07247527 0,11805463 ! fucose catabolic process GO:0019317 16 10 0,000 0,07247527 0,11797108 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07247527 0,11788765 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07247527 0,11780433 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07247527 0,11772114 ! zymogen activation GO:0031638 14 10 0,000 0,07247527 0,11763806 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07247527 0,1175551 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07247527 0,11747226 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07247527 0,11738953 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07247527 0,11730692 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07247527 0,11722442 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07247527 0,11714205 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,07247527 0,11705978 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07247527 0,11697764 ! detection of bacterium GO:0016045 10 10 0,000 0,07247527 0,1168956 ! embryonic gut development GO:0048566 11 10 0,000 0,07247527 0,11681369 ! activation of innate immune response GO:0002218 10 10 0,000 0,07247527 0,11673188 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07247527 0,1166502 ! developmental induction GO:0031128 13 10 0,000 0,07247527 0,11656862 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07247527 0,11648716 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07247527 0,11640582 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07247527 0,11632459 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,07445361 0,11941653 ! glycerolipid biosynthetic process GO:0045017 85 60 1,000 0,07445361 0,11933331 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,07445361 0,11925021 ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,07661182 0,12262156 ! amine catabolic process GO:0009310 90 62 1,000 0,07878975 0,12601977 ! neurotransmitter transport GO:0006836 81 62 1,000 0,07878975 0,12593219 ! rRNA transcription GO:0009303 17 11 0,000 0,07942959 0,1268667 ! respiratory burst GO:0045730 14 11 0,000 0,07942959 0,12677866 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07942959 0,12669074 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07942959 0,12660294 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07942959 0,12651527 ! virus-host interaction GO:0019048 17 11 0,000 0,07942959 0,12642772 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,07942959 0,12634028 ! filopodium assembly GO:0046847 19 11 0,000 0,07942959 0,12625297 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07942959 0,12616578 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07942959 0,12607871 ! mating GO:0007618 14 11 0,000 0,07942959 0,12599176 ! T cell proliferation GO:0042098 20 11 0,000 0,07942959 0,12590493 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07942959 0,12581822 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,07942959 0,12573162 ! bone resorption GO:0045453 16 11 0,000 0,07942959 0,12564515 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07942959 0,1255588 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07942959 0,12547256 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07942959 0,12538644 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07942959 0,12530045 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07942959 0,12521456 ! syncytium formation GO:0006949 15 11 0,000 0,07942959 0,1251288 ! plasma membrane organization GO:0007009 18 11 0,000 0,07942959 0,12504315 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07942959 0,12495763 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07942959 0,12487221 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07942959 0,12478692 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07942959 0,12470174 ! adult heart development GO:0007512 11 11 0,000 0,07942959 0,12461668 ! temperature homeostasis GO:0001659 16 11 0,000 0,07942959 0,12453173 ! L-glutamate transport GO:0015813 16 11 0,000 0,07942959 0,1244469 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07942959 0,12436218 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07942959 0,12427758 ! stem cell development GO:0048864 29 11 0,000 0,07942959 0,1241931 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07942959 0,12410873 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07942959 0,12402447 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07942959 0,12394033 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07942959 0,1238563 ! vasoconstriction GO:0042310 15 11 0,000 0,07942959 0,12377239 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07942959 0,12368859 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07942959 0,1236049 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07942959 0,12352133 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07942959 0,12343787 ! ribosome assembly GO:0042255 13 11 0,000 0,07942959 0,12335452 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07942959 0,12327129 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07942959 0,12318817 ! chromatin silencing GO:0006342 19 11 0,000 0,07942959 0,12310515 ! nucleosome positioning GO:0016584 13 11 0,000 0,07942959 0,12302226 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07942959 0,12293947 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07942959 0,12285679 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07942959 0,12277423 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07942959 0,12269177 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07942959 0,12260943 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07942959 0,1225272 ! male genitalia development GO:0030539 13 11 0,000 0,07942959 0,12244507 ! cholesterol efflux GO:0033344 19 11 0,000 0,07942959 0,12236306 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07942959 0,12228116 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07942959 0,12219936 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07942959 0,12211768 ! defense response to fungus GO:0050832 12 11 0,000 0,07942959 0,1220361 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07942959 0,12195464 ! lysogeny GO:0030069 18 11 0,000 0,07942959 0,12187328 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07942959 0,12179203 ! acrosome reaction GO:0007340 13 11 0,000 0,07942959 0,12171089 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07942959 0,12162986 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,08098699 0,12393219 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,08098699 0,12384979 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,08320314 0,1271543 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,08320314 0,12706987 ! hexose catabolic process GO:0019320 82 64 1,000 0,08320314 0,12698555 ! adaptive immune response GO:0002250 94 64 1,000 0,08320314 0,12690134 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 1,000 0,08543779 0,13022328 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,08543779 0,13013703 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,08543779 0,13005091 ! lactation GO:0007595 20 12 0,000 0,08633215 0,13132536 ! reproductive cellular process GO:0048610 14 12 0,000 0,08633215 0,13123857 ! tRNA modification GO:0006400 14 12 0,000 0,08633215 0,13115188 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08633215 0,13106531 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08633215 0,13097886 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,08633215 0,13089252 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08633215 0,13080629 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08633215 0,13072018 ! non-recombinational repair GO:0000726 19 12 0,000 0,08633215 0,13063418 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08633215 0,13054829 ! peroxisomal transport GO:0043574 21 12 0,000 0,08633215 0,13046252 ! cartilage condensation GO:0001502 18 12 0,000 0,08633215 0,13037685 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08633215 0,13029131 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08633215 0,13020587 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08633215 0,13012054 ! heart looping GO:0001947 15 12 0,000 0,08633215 0,13003533 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08633215 0,12995023 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08633215 0,12986524 ! arginine metabolic process GO:0006525 13 12 0,000 0,08633215 0,12978036 ! methionine metabolic process GO:0006555 13 12 0,000 0,08633215 0,12969559 ! Golgi organization GO:0007030 18 12 0,000 0,08633215 0,12961093 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,08633215 0,12952639 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08633215 0,12944195 ! monoamine transport GO:0015844 13 12 0,000 0,08633215 0,12935762 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08633215 0,1292734 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,08633215 0,1291893 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08633215 0,1291053 ! L-amino acid transport GO:0015807 20 12 0,000 0,08633215 0,12902141 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08633215 0,12893763 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08633215 0,12885396 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08633215 0,1287704 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08633215 0,12868694 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08633215 0,12860359 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08633215 0,12852036 ! cerebellum development GO:0021549 13 12 0,000 0,08633215 0,12843723 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08633215 0,1283542 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08633215 0,12827129 ! histone acetylation GO:0016573 23 12 0,000 0,08633215 0,12818848 ! histone methylation GO:0016571 15 12 0,000 0,08633215 0,12810577 ! autonomic nervous system development GO:0048483 23 12 0,000 0,08633215 0,12802318 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08633215 0,12794069 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,08633215 0,12785831 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08633215 0,12777603 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08633215 0,12769386 ! intestinal absorption GO:0050892 19 12 0,000 0,08633215 0,12761179 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08633215 0,12752983 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08633215 0,12744798 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,08633215 0,12736623 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08633215 0,12728458 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,08633215 0,12720304 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08633215 0,12712161 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08633215 0,12704028 ! microspike assembly GO:0030035 23 12 0,000 0,08633215 0,12695905 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08633215 0,12687792 ! response to cold GO:0009409 14 12 0,000 0,08633215 0,1267969 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,08769055 0,12870981 ! antigen processing and presentation GO:0019882 96 66 1,000 0,08769055 0,12862772 ! axon guidance GO:0007411 99 66 1,000 0,08769055 0,12854574 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,08769055 0,12846386 ! regulation of immune effector process GO:0002697 101 66 1,000 0,08769055 0,12838209 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,08996102 0,13162236 ! rhythmic process GO:0048511 105 68 1,000 0,09224882 0,13488385 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,09318335 0,13616373 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,09318335 0,13607728 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,09318335 0,13599093 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09318335 0,1359047 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,09318335 0,13581858 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09318335 0,13573256 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09318335 0,13564665 ! lipid localization GO:0010876 24 13 0,000 0,09318335 0,13556086 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09318335 0,13547517 ! organelle fusion GO:0048284 28 13 0,000 0,09318335 0,13538959 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09318335 0,13530411 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,09318335 0,13521875 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09318335 0,13513349 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09318335 0,13504834 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09318335 0,1349633 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09318335 0,13487836 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09318335 0,13479353 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09318335 0,13470881 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09318335 0,13462419 ! bone mineralization GO:0030282 15 13 0,000 0,09318335 0,13453968 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,09318335 0,13445528 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,09318335 0,13437098 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09318335 0,13428679 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09318335 0,1342027 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09318335 0,13411872 ! genitalia development GO:0048806 15 13 0,000 0,09318335 0,13403484 ! regulation of cellular pH GO:0030641 20 13 0,000 0,09318335 0,13395107 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,09318335 0,1338674 ! tissue regeneration GO:0042246 21 13 0,000 0,09318335 0,13378384 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09318335 0,13370038 ! cofactor transport GO:0051181 19 13 0,000 0,09318335 0,13361703 ! NADP metabolic process GO:0006739 18 13 0,000 0,09318335 0,13353378 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,09318335 0,13345063 ! gas transport GO:0015669 18 13 0,000 0,09318335 0,13336759 ! regulation of RNA stability GO:0043487 28 13 0,000 0,09318335 0,13328465 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09318335 0,13320181 ! regulation of axon extension GO:0030516 23 13 0,000 0,09318335 0,13311908 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,09318335 0,13303645 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09318335 0,13295392 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09318335 0,13287149 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09318335 0,13278917 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09318335 0,13270694 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,09687489 0,13787886 ! muscle cell differentiation GO:0042692 104 71 1,000 0,0992124 0,14111843 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,0992124 0,14103122 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,0992124 0,14094411 ! monosaccharide catabolic process GO:0046365 91 71 1,000 0,0992124 0,1408571 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09998357 0,14186441 ! superoxide anion generation GO:0042554 18 14 0,000 0,09998357 0,14177695 ! neuron maturation GO:0042551 21 14 0,000 0,09998357 0,14168959 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09998357 0,14160235 ! myotube differentiation GO:0014902 21 14 0,000 0,09998357 0,14151521 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09998357 0,14142817 ! inositol metabolic process GO:0006020 20 14 0,000 0,09998357 0,14134125 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09998357 0,14125443 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09998357 0,14116772 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09998357 0,14108111 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09998357 0,14099461 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09998357 0,14090822 ! response to cAMP GO:0051591 19 14 0,000 0,09998357 0,14082193 ! limbic system development GO:0021761 25 14 0,000 0,09998357 0,14073575 ! startle response GO:0001964 21 14 0,000 0,09998357 0,14064967 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09998357 0,1405637 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09998357 0,14047783 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09998357 0,14039207 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09998357 0,14030641 ! glycine metabolic process GO:0006544 22 14 0,000 0,09998357 0,14022086 ! pituitary gland development GO:0021983 23 14 0,000 0,09998357 0,14013541 ! cellular response to starvation GO:0009267 21 14 0,000 0,09998357 0,14005007 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09998357 0,13996483 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09998357 0,13987969 ! regulation of heart rate GO:0002027 23 14 0,000 0,09998357 0,13979466 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09998357 0,13970973 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09998357 0,1396249 ! embryo implantation GO:0007566 27 14 0,000 0,09998357 0,13954018 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09998357 0,13945556 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,09998357 0,13937104 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09998357 0,13928662 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09998357 0,13920231 ! axon cargo transport GO:0008088 27 14 0,000 0,09998357 0,13911809 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09998357 0,13903398 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09998357 0,13894998 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09998357 0,13886607 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09998357 0,13878226 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09998357 0,13869856 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09998357 0,13861496 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09998357 0,13853145 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09998357 0,13844805 ! muscle maintenance GO:0046716 19 14 0,000 0,09998357 0,13836475 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09998357 0,13828155 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09998357 0,13819844 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09998357 0,13811544 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,09998357 0,13803254 ! cell killing GO:0001906 20 14 0,000 0,09998357 0,13794974 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,09998357 0,13786703 ! cilium assembly GO:0042384 20 14 0,000 0,09998357 0,13778443 ! response to hypoxia GO:0001666 132 72 1,000 0,10156573 0,13988095 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,10156573 0,13979724 ! tube morphogenesis GO:0035239 118 73 1,000 0,10393453 0,14297214 ! phospholipid biosynthetic process GO:0008654 102 74 1,000 0,10631843 0,14616402 ! response to oxygen levels GO:0070482 137 74 1,000 0,10631843 0,1460767 ! digestion GO:0007586 97 74 1,000 0,10631843 0,14598949 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,10631843 0,14590239 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10673318 0,1463842 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10673318 0,14629697 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10673318 0,14620983 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10673318 0,1461228 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10673318 0,14603588 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10673318 0,14594905 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10673318 0,14586233 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10673318 0,14577572 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10673318 0,1456892 ! adult walking behavior GO:0007628 25 15 0,000 0,10673318 0,14560279 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10673318 0,14551648 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10673318 0,14543028 ! myoblast differentiation GO:0045445 27 15 0,000 0,10673318 0,14534417 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10673318 0,14525817 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10673318 0,14517227 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10673318 0,14508647 ! cerebral cortex development GO:0021987 29 15 0,000 0,10673318 0,14500077 ! response to osmotic stress GO:0006970 22 15 0,000 0,10673318 0,14491518 ! vesicle coating GO:0006901 25 15 0,000 0,10673318 0,14482968 ! DNA integration GO:0015074 22 15 0,000 0,10673318 0,14474429 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10673318 0,14465899 ! regulation of vasodilation GO:0042312 24 15 0,000 0,10673318 0,1445738 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10673318 0,1444887 ! neuron recognition GO:0008038 22 15 0,000 0,10673318 0,14440371 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10673318 0,14431882 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,10673318 0,14423402 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10673318 0,14414933 ! biomineral formation GO:0031214 18 15 0,000 0,10673318 0,14406474 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10673318 0,14398024 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10673318 0,14389584 ! dopamine metabolic process GO:0042417 30 15 0,000 0,10673318 0,14381155 ! organic cation transport GO:0015695 19 15 0,000 0,10673318 0,14372735 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10673318 0,14364325 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,10673318 0,14355925 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,10673318 0,14347534 ! peptide hormone processing GO:0016486 19 15 0,000 0,10673318 0,14339154 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10673318 0,14330783 ! amine biosynthetic process GO:0009309 97 76 1,000 0,11113013 0,14912445 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,11113013 0,1490375 ! protein secretion GO:0009306 27 16 0,000 0,11343255 0,15203664 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,11343255 0,15194809 ! bone remodeling GO:0046849 24 16 0,000 0,11343255 0,15185964 ! endothelial cell migration GO:0043542 22 16 0,000 0,11343255 0,1517713 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,11343255 0,15168306 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,11343255 0,15159493 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,11343255 0,15150689 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,11343255 0,15141896 ! glial cell development GO:0021782 24 16 0,000 0,11343255 0,15133113 ! patterning of blood vessels GO:0001569 24 16 0,000 0,11343255 0,1512434 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,11343255 0,15115578 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,11343255 0,15106825 ! protein polyubiquitination GO:0000209 26 16 0,000 0,11343255 0,15098083 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,11343255 0,1508935 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,11343255 0,15080628 ! fructose metabolic process GO:0006000 20 16 0,000 0,11343255 0,15071916 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,11343255 0,15063214 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,11343255 0,15054522 ! protein export from nucleus GO:0006611 24 16 0,000 0,11343255 0,1504584 ! negative regulation of immune response GO:0050777 28 16 0,000 0,11343255 0,15037168 ! DNA replication initiation GO:0006270 25 16 0,000 0,11343255 0,15028506 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,11343255 0,15019854 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,11343255 0,15011212 ! diencephalon development GO:0021536 25 16 0,000 0,11343255 0,1500258 ! neural crest cell migration GO:0001755 24 16 0,000 0,11343255 0,14993958 ! G1 phase GO:0051318 27 16 0,000 0,11343255 0,14985346 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,11343255 0,14976743 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,11343255 0,14968151 ! steroid catabolic process GO:0006706 22 16 0,000 0,11343255 0,14959568 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,11343255 0,14950995 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,11343255 0,14942432 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,11343255 0,14933879 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,11343255 0,14925336 ! sperm-egg recognition GO:0035036 16 16 0,000 0,11343255 0,14916802 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,11343255 0,14908278 ! nerve development GO:0021675 18 16 0,000 0,11343255 0,14899764 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,11343255 0,1489126 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,11343255 0,14882765 ! negative regulation of translation GO:0017148 22 16 0,000 0,11343255 0,1487428 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,11355724 0,14882145 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,11355724 0,1487367 ! protein ubiquitination GO:0016567 125 77 1,000 0,11355724 0,14865204 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,11355724 0,14856749 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,11355724 0,14848303 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,11599805 0,15158836 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,11599805 0,15150228 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,11845223 0,15461982 ! cellular respiration GO:0045333 107 79 1,000 0,11845223 0,15453212 ! T cell activation GO:0042110 134 79 1,000 0,11845223 0,15444452 ! regulation of lyase activity GO:0051339 133 79 1,000 0,11845223 0,15435701 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,12008206 0,15639227 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,12008206 0,15630376 ! negative regulation of defense response GO:0031348 19 17 0,000 0,12008206 0,15621535 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,12008206 0,15612704 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,12008206 0,15603884 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,12008206 0,15595073 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,12008206 0,15586272 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,12008206 0,15577481 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,12008206 0,155687 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,12008206 0,15559929 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,12008206 0,15551168 ! memory GO:0007613 25 17 0,000 0,12008206 0,15542416 ! keratinization GO:0031424 17 17 0,000 0,12008206 0,15533675 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,12008206 0,15524943 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,12008206 0,15516221 ! retinoid metabolic process GO:0001523 22 17 0,000 0,12008206 0,15507509 GO:0016101|diterpenoid metabolic process, ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,12008206 0,15498807 ! vacuolar transport GO:0007034 24 17 0,000 0,12008206 0,15490114 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,12008206 0,15481432 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,12008206 0,15472759 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,12008206 0,15464095 ! membrane budding GO:0006900 29 17 0,000 0,12008206 0,15455442 ! heme metabolic process GO:0042168 27 17 0,000 0,12008206 0,15446798 ! body fluid secretion GO:0007589 27 17 0,000 0,12008206 0,15438163 ! stem cell differentiation GO:0048863 36 17 0,000 0,12008206 0,15429539 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,12008206 0,15420924 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,12008206 0,15412318 ! sensory perception of pain GO:0019233 23 17 0,000 0,12008206 0,15403722 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,12008206 0,15395136 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,12008206 0,15386559 ! synaptogenesis GO:0007416 24 17 0,000 0,12008206 0,15377992 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,12008206 0,15369435 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,12008206 0,15360887 ! cell-cell junction organization GO:0045216 25 17 0,000 0,12008206 0,15352348 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,12008206 0,15343819 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,12008206 0,15335299 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,12008206 0,15326789 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,12339939 0,15741464 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,12339939 0,15732738 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,1258917 0,16041602 GO:0060348|bone development, ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,12668208 0,16133376 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,12668208 0,16124448 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,12668208 0,16115529 ! cAMP metabolic process GO:0046058 33 18 0,000 0,12668208 0,16106621 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12668208 0,16097722 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12668208 0,16088833 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12668208 0,16079954 ! axis specification GO:0009798 26 18 0,000 0,12668208 0,16071085 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,12668208 0,16062226 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12668208 0,16053376 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12668208 0,16044536 ! glutamine metabolic process GO:0006541 23 18 0,000 0,12668208 0,16035706 ! pigmentation during development GO:0048066 31 18 0,000 0,12668208 0,16026885 ! central nervous system neuron development GO:0021954 30 18 0,000 0,12668208 0,16018074 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,12668208 0,16009273 ! fucose metabolic process GO:0006004 26 18 0,000 0,12668208 0,16000482 ! response to fungus GO:0009620 19 18 0,000 0,12668208 0,159917 ! peptide cross-linking GO:0018149 31 18 0,000 0,12668208 0,15982928 ! heart process GO:0003015 27 18 0,000 0,12668208 0,15974165 GO:0060047|heart contraction, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,12668208 0,15965412 ! visual learning GO:0008542 35 18 0,000 0,12668208 0,15956669 ! somitogenesis GO:0001756 24 18 0,000 0,12668208 0,15947935 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,12668208 0,15939211 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12668208 0,15930496 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,12668208 0,15921791 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12668208 0,15913095 ! vitamin transport GO:0051180 24 18 0,000 0,12668208 0,15904409 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,12668208 0,15895732 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12668208 0,15887065 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12668208 0,15878407 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,12668208 0,15869759 ! cell-cell recognition GO:0009988 20 18 0,000 0,12668208 0,1586112 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12668208 0,1585249 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12668208 0,1584387 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,12668208 0,15835259 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,12839608 0,16040793 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! sterol metabolic process GO:0016125 120 84 1,000 0,13091221 0,16346259 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,13323296 0,16627011 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,13323296 0,16617994 ! positive regulation of ossification GO:0045778 30 19 0,000 0,13323296 0,16608987 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,13323296 0,1659999 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,13323296 0,16591002 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,13323296 0,16582024 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,13323296 0,16573056 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,13323296 0,16564098 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,13323296 0,16555149 ! sensory perception of taste GO:0050909 23 19 0,000 0,13323296 0,1654621 ! smooth muscle contraction GO:0006939 36 19 0,000 0,13323296 0,1653728 ! peroxisome organization GO:0007031 29 19 0,000 0,13323296 0,16528361 ! digestive system process GO:0022600 30 19 0,000 0,13323296 0,16519451 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,13323296 0,1651055 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,13323296 0,16501659 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,13323296 0,16492778 ! response to starvation GO:0042594 30 19 0,000 0,13323296 0,16483906 ! sex determination GO:0007530 29 19 0,000 0,13323296 0,16475043 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,13323296 0,16466191 ! plasma membrane fusion GO:0045026 23 19 0,000 0,13323296 0,16457347 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,13323296 0,16448514 ! cytolysis GO:0019835 20 19 0,000 0,13323296 0,16439689 ! vasodilation GO:0042311 33 19 0,000 0,13323296 0,16430874 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,13323296 0,16422069 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,13323296 0,16413273 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,13323296 0,16404486 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,13323296 0,16395709 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,13323296 0,16386942 ! sarcomere organization GO:0045214 23 19 0,000 0,13323296 0,16378183 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,13323296 0,16369434 ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,13323296 0,16360694 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,13323296 0,16351964 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,13323296 0,16343243 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,13323296 0,16334531 ! rRNA metabolic process GO:0016072 107 85 1,000 0,13343977 0,16351171 GO:0006364|rRNA processing, ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,13343977 0,16342464 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,13597846 0,16644516 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,13852797 0,1694757 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,13852797 0,1693856 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13973508 0,17077082 ! iron ion transport GO:0006826 37 20 0,000 0,13973508 0,17068013 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13973508 0,17058953 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13973508 0,17049903 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,13973508 0,17040863 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13973508 0,17031832 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,13973508 0,17022811 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,13973508 0,170138 ! spinal cord development GO:0021510 31 20 0,000 0,13973508 0,17004798 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,13973508 0,16995805 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,13973508 0,16986822 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13973508 0,16977849 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,13973508 0,16968885 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,13973508 0,1695993 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13973508 0,16950985 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,13973508 0,16942049 ! pallium development GO:0021543 38 20 0,000 0,13973508 0,16933123 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13973508 0,16924206 ! collagen catabolic process GO:0030574 25 20 0,000 0,13973508 0,16915299 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13973508 0,16906401 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13973508 0,16897512 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13973508 0,16888633 ! actin filament-based movement GO:0030048 34 20 0,000 0,13973508 0,16879763 ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,14108799 0,17034246 GO:0016054|organic acid catabolic process, ! regulation of neurogenesis GO:0050767 153 89 1,000 0,14365824 0,17335464 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,14365824 0,17326374 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,14618879 0,17622338 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,14618879 0,17613107 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,14618879 0,17603886 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,14618879 0,17594674 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,14618879 0,17585471 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,14618879 0,17576279 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,14618879 0,17567096 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,14618879 0,17557922 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,14618879 0,17548759 ! protein amino acid acylation GO:0043543 37 21 0,000 0,14618879 0,17539604 ! vesicle docking GO:0048278 27 21 0,000 0,14618879 0,1753046 ! phototransduction GO:0007602 25 21 0,000 0,14618879 0,17521324 ! dendrite development GO:0016358 35 21 0,000 0,14618879 0,17512199 ! visual behavior GO:0007632 39 21 0,000 0,14618879 0,17503082 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,14618879 0,17493976 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,14618879 0,17484879 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,14618879 0,17475791 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,14618879 0,17466712 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,14618879 0,17457644 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,14618879 0,17448584 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,14618879 0,17439534 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,14618879 0,17430493 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,14618879 0,17421462 ! fatty acid transport GO:0015908 30 21 0,000 0,14618879 0,1741244 ! immunoglobulin production GO:0002377 33 21 0,000 0,14618879 0,17403427 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,14618879 0,17394424 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,14618879 0,1738543 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,14618879 0,17376445 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,14618879 0,1736747 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,14618879 0,17358504 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,14618879 0,17349547 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,14618879 0,17340599 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,14618879 0,17331661 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,14618879 0,17322731 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,14618879 0,17313811 ! leukocyte differentiation GO:0002521 143 90 1,000 0,14623841 0,17310774 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,15142739 0,17915792 ! sulfur metabolic process GO:0006790 118 92 1,000 0,15142739 0,1790658 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,15259445 0,18035315 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,15259445 0,18026052 ! viral genome replication GO:0019079 29 22 0,000 0,15259445 0,18016799 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,15259445 0,18007555 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,15259445 0,1799832 ! leukocyte adhesion GO:0007159 38 22 0,000 0,15259445 0,17989095 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,15259445 0,17979879 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,15259445 0,17970673 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,15259445 0,17961476 ! vasculogenesis GO:0001570 33 22 0,000 0,15259445 0,17952288 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,15259445 0,1794311 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,15259445 0,17933942 ! lysosome organization GO:0007040 37 22 0,000 0,15259445 0,17924782 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,15259445 0,17915632 GO:0051693|actin filament capping, ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,15259445 0,17906492 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,15259445 0,1789736 ! membrane depolarization GO:0051899 35 22 0,000 0,15259445 0,17888238 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,15259445 0,17879126 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,15259445 0,17870022 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,15259445 0,17860928 ! neural tube closure GO:0001843 33 22 0,000 0,15259445 0,17851843 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,15259445 0,17842768 ! protein tetramerization GO:0051262 39 22 0,000 0,15259445 0,17833701 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,15403562 0,17992988 ! electron transport chain GO:0022900 123 94 1,000 0,15665264 0,18289395 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15895242 0,18548481 ! vesicle targeting GO:0006903 32 23 0,000 0,15895242 0,18539075 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15895242 0,18529679 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15895242 0,18520292 ! interaction with host GO:0051701 37 23 0,000 0,15895242 0,18510915 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,15895242 0,18501547 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,15895242 0,18492188 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,15895242 0,18482839 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15895242 0,184735 ! cell fate determination GO:0001709 45 23 0,000 0,15895242 0,1846417 ! pentose metabolic process GO:0019321 31 23 0,000 0,15895242 0,18454849 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,15895242 0,18445538 ! spermatid development GO:0007286 33 23 0,000 0,15895242 0,18436236 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,15895242 0,18426944 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15895242 0,18417661 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15895242 0,18408387 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15895242 0,18399123 ! telomere organization GO:0032200 32 23 0,000 0,15895242 0,18389867 GO:0000723|telomere maintenance, ! regulation of amine transport GO:0051952 38 23 0,000 0,15895242 0,18380622 ! liver development GO:0001889 40 23 0,000 0,15895242 0,18371385 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,16191197 0,18704045 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,16526305 0,19081577 ! initiation of viral infection GO:0019059 42 24 0,000 0,16526305 0,19072002 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,16526305 0,19062438 ! superoxide metabolic process GO:0006801 32 24 0,000 0,16526305 0,19052883 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,16526305 0,19043337 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,16526305 0,19033801 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,16526305 0,19024275 ! sperm motility GO:0030317 27 24 0,000 0,16526305 0,19014758 ! vacuole organization GO:0007033 39 24 0,000 0,16526305 0,1900525 ! neural crest cell development GO:0014032 39 24 0,000 0,16526305 0,18995752 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,16526305 0,18986264 ! negative regulation of cell development GO:0010721 56 24 0,000 0,16526305 0,18976785 GO:0050768|negative regulation of neurogenesis, ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,16526305 0,18967316 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,16526305 0,18957856 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,16526305 0,18948405 ! glutathione metabolic process GO:0006749 29 24 0,000 0,16526305 0,18938964 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,16526305 0,18929532 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,17152668 0,19637201 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,17152668 0,19627431 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,17152668 0,19617671 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,17152668 0,19607921 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,17152668 0,1959818 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,17152668 0,19588449 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,17152668 0,19578728 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,17152668 0,19569016 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,17152668 0,19559314 ! phospholipid transport GO:0015914 35 25 0,000 0,17152668 0,19549622 ! detection of light stimulus GO:0009583 30 25 0,000 0,17152668 0,19539939 ! regulation of translation GO:0006417 151 100 1,000 0,17252424 0,19643849 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,17252424 0,19634129 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,17252424 0,19624419 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,17774367 0,20208129 ! translational initiation GO:0006413 43 26 0,000 0,17774367 0,20198145 ! regulation of pH GO:0006885 36 26 0,000 0,17774367 0,2018817 ! circadian rhythm GO:0007623 42 26 0,000 0,17774367 0,20178206 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,17774367 0,20168251 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,17774367 0,20158306 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,17774367 0,20148371 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,17774367 0,20138446 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,17774367 0,2012853 ! spermatid differentiation GO:0048515 36 26 0,000 0,17774367 0,20118624 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,17774367 0,20108728 ! regulation of coagulation GO:0050818 39 26 0,000 0,17774367 0,20098842 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,18391436 0,2078639 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,18391436 0,2077618 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,18391436 0,20765981 ! membrane docking GO:0022406 39 27 0,000 0,18391436 0,20755792 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,18391436 0,20745612 ! catechol metabolic process GO:0009712 43 27 0,000 0,18391436 0,20735443 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! myofibril assembly GO:0030239 36 27 0,000 0,18391436 0,20725283 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,18391436 0,20715134 ! natural killer cell activation GO:0030101 35 27 0,000 0,18391436 0,20704994 ! lipid oxidation GO:0034440 38 27 0,000 0,18391436 0,20694865 GO:0019395|fatty acid oxidation, ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,18391436 0,20684745 ! gene silencing GO:0016458 41 27 0,000 0,18391436 0,20674635 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1900391 0,21352707 ! phenol metabolic process GO:0018958 44 28 0,000 0,1900391 0,21342281 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,1900391 0,21331865 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1900391 0,2132146 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,1900391 0,21311064 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,1900391 0,21300678 GO:0055092|sterol homeostasis, ! complement activation, classical pathway GO:0006958 36 28 0,000 0,1900391 0,21290303 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,1900391 0,21279938 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,1900391 0,21269583 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1900391 0,21259237 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1900391 0,21248902 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1900391 0,21238577 ! mesoderm formation GO:0001707 46 28 0,000 0,1900391 0,21228262 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1900391 0,21217957 ! BMP signaling pathway GO:0030509 40 28 0,000 0,1900391 0,21207662 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,1900391 0,21197377 ! neural tube formation GO:0001841 41 28 0,000 0,1900391 0,21187102 ! placenta development GO:0001890 37 28 0,000 0,1900391 0,21176837 ! protein targeting to membrane GO:0006612 53 29 0,000 0,19611821 0,21843675 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,19611821 0,21833102 ! mismatch repair GO:0006298 34 29 0,000 0,19611821 0,21822539 ! muscle cell development GO:0055001 38 29 0,000 0,19611821 0,21811987 ! formation of primary germ layer GO:0001704 48 29 0,000 0,19611821 0,21801444 ! telencephalon development GO:0021537 52 29 0,000 0,19611821 0,21790912 ! eye morphogenesis GO:0048592 51 29 0,000 0,19611821 0,2178039 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,19611821 0,21769879 ! collagen metabolic process GO:0032963 40 30 0,000 0,20215205 0,22428833 ! organic anion transport GO:0015711 51 30 0,000 0,20215205 0,22418019 ! cholesterol transport GO:0030301 46 30 0,000 0,20215205 0,22407215 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,20215205 0,22396421 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,20215205 0,22385638 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,20215205 0,22374866 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,20215205 0,22364103 ! ceramide metabolic process GO:0006672 43 30 0,000 0,20215205 0,22353351 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,20215205 0,2234261 ! adult locomotory behavior GO:0008344 47 30 0,000 0,20215205 0,22331878 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,20215205 0,22321157 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,20215205 0,22310447 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,20215205 0,22299746 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,20215205 0,22289056 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,20814093 0,22938388 ! glial cell differentiation GO:0010001 55 31 0,000 0,20814093 0,22927402 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,20814093 0,22916426 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,20814093 0,22905462 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,20814093 0,22894507 ! segmentation GO:0035282 41 31 0,000 0,20814093 0,22883564 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,20814093 0,2287263 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,20814093 0,22861707 ! cell fate specification GO:0001708 37 31 0,000 0,20814093 0,22850795 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,20814093 0,22839893 ! RNA modification GO:0009451 40 31 0,000 0,20814093 0,22829001 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,21408521 0,2346978 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,21408521 0,23458598 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,21408521 0,23447428 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,21408521 0,23436268 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,21408521 0,23425118 ! cytokine production GO:0001816 44 32 0,000 0,21408521 0,23413979 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,21408521 0,23402851 ! vesicle localization GO:0051648 47 32 0,000 0,21408521 0,23391733 ! RNA export from nucleus GO:0006405 44 33 0,000 0,2199852 0,24024974 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,2199852 0,24013572 ! actomyosin structure organization GO:0031032 43 33 0,000 0,2199852 0,2400218 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,2199852 0,23990799 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,2199852 0,23979429 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,2199852 0,2396807 ! lipid homeostasis GO:0055088 55 33 0,000 0,2199852 0,23956722 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,2199852 0,23945384 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,2199852 0,23934057 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,2199852 0,2392274 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,2199852 0,23911435 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,2199852 0,2390014 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,22584123 0,2452478 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,22584123 0,24513206 ! feeding behavior GO:0007631 45 34 0,000 0,22584123 0,24501643 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,22584123 0,24490091 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,22584123 0,2447855 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,22584123 0,2446702 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,22584123 0,24455501 ! neuron migration GO:0001764 46 34 0,000 0,22584123 0,24443992 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,22584123 0,24432495 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,22584123 0,24421008 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,22584123 0,24409532 ! embryonic organ development GO:0048568 45 34 0,000 0,22584123 0,24398067 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,22584123 0,24386612 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,23165364 0,25002504 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,23165364 0,24990777 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,23165364 0,24979061 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,23165364 0,24967355 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,23165364 0,24955661 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,23165364 0,24943978 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 48 35 0,000 0,23165364 0,24932305 ! organic ether metabolic process GO:0018904 46 36 0,000 0,23742273 0,25541267 ! tissue remodeling GO:0048771 62 36 0,000 0,23742273 0,25529326 ! neural tube development GO:0021915 50 36 0,000 0,23742273 0,25517396 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,23742273 0,25505478 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,23742273 0,2549357 ! glucan metabolic process GO:0044042 49 36 0,000 0,23742273 0,25481674 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,24314883 0,26084063 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,24314883 0,26071903 ! learning GO:0007612 67 37 0,000 0,24314883 0,26059754 ! ion transmembrane transport GO:0034220 56 37 0,000 0,24314883 0,26047616 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,24314883 0,2603549 ! amino acid activation GO:0043038 52 37 0,000 0,24314883 0,26023375 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! gliogenesis GO:0042063 71 38 0,000 0,24883227 0,26619266 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,24883227 0,26606891 ! phagocytosis GO:0006909 60 38 0,000 0,24883227 0,26594527 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,25447335 0,27184798 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,25447335 0,27172177 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,25447335 0,27159568 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,25447335 0,27146971 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,25447335 0,27134386 ! chromatin remodeling GO:0006338 68 39 0,000 0,25447335 0,27121812 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,25447335 0,2710925 ! JNK cascade GO:0007254 54 39 0,000 0,25447335 0,27096699 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,26007238 0,27680078 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,26007238 0,27667275 ! regulation of tube size GO:0035150 60 40 0,000 0,26007238 0,27654484 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,26007238 0,27641704 ! peptide metabolic process GO:0006518 56 40 0,000 0,26007238 0,27628937 ! inner ear development GO:0048839 57 40 0,000 0,26007238 0,27616181 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,26007238 0,27603437 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,26007238 0,27590705 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,26562969 0,28167279 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,26562969 0,28154299 ! striated muscle contraction GO:0006941 62 41 0,000 0,26562969 0,2814133 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,26562969 0,28128374 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,26562969 0,28115429 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,27114557 0,28686054 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,27114557 0,28672865 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,27114557 0,28659688 ! excretion GO:0007588 63 42 0,000 0,27114557 0,28646523 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,27114557 0,28633371 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,27662034 0,29198108 ! neuromuscular process GO:0050905 79 43 0,000 0,27662034 0,29184715 ! tRNA processing GO:0008033 49 43 0,000 0,27662034 0,29171333 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,28205429 0,29730746 ! regulation of ion transport GO:0043269 57 44 0,000 0,28205429 0,29717127 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,28205429 0,2970352 ! regulation of translational initiation GO:0006446 64 45 0,000 0,28744774 0,30257657 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,28744774 0,30243815 ! cell recognition GO:0008037 58 45 0,000 0,28744774 0,30229986 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,29280097 0,30778896 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,29280097 0,30764835 ! cell redox homeostasis GO:0045454 63 46 0,000 0,29280097 0,30750787 ! histone modification GO:0016570 68 46 0,000 0,29280097 0,30736752 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,29811429 0,31280241 ! viral infectious cycle GO:0019058 71 47 0,000 0,29811429 0,31265977 ! covalent chromatin modification GO:0016569 75 47 0,000 0,29811429 0,31251726 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,29811429 0,31237489 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,29811429 0,31223264 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,29811429 0,31209052 ! chloride transport GO:0006821 67 48 0,000 0,303388 0,31746697 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,303388 0,3173226 ! gastrulation GO:0007369 73 48 0,000 0,303388 0,31717836 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,303388 0,31703425 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,303388 0,31689028 ! regulation of endocytosis GO:0030100 63 48 0,000 0,303388 0,31674643 ! nuclear export GO:0051168 69 48 0,000 0,303388 0,31660272 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,30862238 0,32191903 ! sensory perception of smell GO:0007608 61 49 0,000 0,30862238 0,3217731 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,30862238 0,32162731 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,30862238 0,32148164 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,30862238 0,32133611 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,30862238 0,32119071 ! membrane fusion GO:0006944 80 50 0,000 0,31381772 0,32644991 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,31381772 0,32630233 ! proton transport GO:0015992 75 50 0,000 0,31381772 0,32615489 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,31381772 0,32600757 ! hydrogen transport GO:0006818 77 51 0,000 0,31897432 0,33121487 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,31897432 0,33106541 GO:0010863|positive regulation of phospholipase C activity, ! adult behavior GO:0030534 80 51 0,000 0,31897432 0,33091608 ! transition metal ion transport GO:0000041 74 52 0,000 0,32409247 0,33607424 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,32409247 0,33592279 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,32409247 0,33577148 ! single fertilization GO:0007338 59 53 0,000 0,32917244 0,34088096 ! cell projection assembly GO:0030031 76 53 0,000 0,32917244 0,34072755 ! amino acid transport GO:0006865 84 54 0,000 0,33421452 0,345791 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,33421452 0,34563552 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,33421452 0,34548018 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,33421452 0,34532497 ! exocytosis GO:0006887 74 55 0,000 0,33921899 0,35033842 ! mesoderm development GO:0007498 76 55 0,000 0,33921899 0,35018118 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,33921899 0,35002408 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,34418613 0,35499017 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,34911621 0,35991362 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,34911621 0,35975236 ! camera-type eye development GO:0043010 88 57 0,000 0,34911621 0,35959126 ! viral reproductive process GO:0022415 87 58 0,000 0,35400951 0,36446816 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,35400951 0,36430509 ! lung development GO:0030324 94 59 0,000 0,3588663 0,36913797 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,3588663 0,36897295 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,3588663 0,36880809 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,36368686 0,37359525 GO:0035113|embryonic appendage morphogenesis, ! fertilization GO:0009566 68 60 0,000 0,36368686 0,37342847 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,36847144 0,37817238 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,37322032 0,38287544 ! respiratory tube development GO:0030323 99 62 0,000 0,37322032 0,38270474 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,37322032 0,3825342 ! viral reproduction GO:0016032 92 63 0,000 0,37793376 0,38719272 ! regulation of lipase activity GO:0060191 109 63 0,000 0,37793376 0,38702033 ! appendage morphogenesis GO:0035107 93 64 0,000 0,38261202 0,3916367 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,38261202 0,39146248 ! respiratory system development GO:0060541 100 64 0,000 0,38261202 0,39128842 ! appendage development GO:0048736 94 65 0,000 0,38725537 0,39586105 GO:0060173|limb development, ! activation of immune response GO:0002253 83 65 0,000 0,38725537 0,39568519 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,39643835 0,40488819 ! learning or memory GO:0007611 123 68 0,000 0,40097849 0,40934333 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,40097849 0,40916173 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,40097849 0,40898028 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,40097849 0,408799 ! inorganic anion transport GO:0015698 93 68 0,000 0,40097849 0,40861787 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,40548474 0,41302697 ! eye development GO:0001654 111 70 0,000 0,40995735 0,41739792 ! amine transport GO:0015837 101 70 0,000 0,40995735 0,41721323 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,41439656 0,42154449 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,41880263 0,42583822 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,4231758 0,43009471 ! protein import into nucleus GO:0006606 118 74 0,000 0,42751631 0,43431427 ! nuclear import GO:0051170 121 75 0,000 0,43182441 0,43849719 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,43182441 0,43830368 ! tRNA metabolic process GO:0006399 95 76 0,000 0,43610033 0,4424485 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,44034432 0,44655729 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,44873743 0,45486827 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,44873743 0,45466788 ! chromatin assembly GO:0031497 102 80 0,000 0,45288703 0,45867026 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,45288703 0,45846838 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,45288703 0,45826668 ! forebrain development GO:0030900 131 80 0,000 0,45288703 0,45806516 ! mRNA transport GO:0051028 121 81 0,000 0,45700562 0,46202766 ! regulation of neurological system process GO:0031644 122 81 0,000 0,45700562 0,46182466 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,46515073 0,46984923 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,4691777 0,47370883 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,47317459 0,47753468 ! nucleosome organization GO:0034728 114 87 0,000 0,48107897 0,48529896 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,48107897 0,4850862 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,48107897 0,48487363 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,48498691 0,48859829 ! establishment of RNA localization GO:0051236 128 88 0,000 0,48498691 0,48838436 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,48886564 0,49207483 ! hormone metabolic process GO:0042445 121 90 0,000 0,49271539 0,49573289 ! RNA localization GO:0006403 135 91 0,000 0,49653636 0,49935882 ! ATP metabolic process GO:0046034 137 91 0,000 0,49653636 0,49914057 ! positive regulation of immune response GO:0050778 121 92 0,000 0,50032876 0,50273314 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,50409282 0,5062941 ! angiogenesis GO:0001525 149 95 0,000 0,51153672 0,51354625 ! carboxylic acid transport GO:0046942 147 95 0,000 0,51153672 0,51332219 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,51521698 0,51678982 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,51886972 0,52022683 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,52609347 0,52723964 ! protein import GO:0017038 156 99 0,000 0,52609347 0,52701001 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,52966487 0,53035664 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,52966487 0,53012585 ! divalent metal ion transport GO:0070838 171 100 0,000 0,52966487 0,52989526 ! protein localization in organelle GO:0033365 161 100 0,000 0,52966487 0,52966487