pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6252-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of locomotion GO:0040017 39 21 4,000 1,475E-07 3,548E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 4,000 1,475E-07 1,774E-04 ! regulation of chemotaxis GO:0050920 40 22 4,000 1,899E-07 1,523E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 5,000 2,345E-07 1,41E-04 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 6,000 2,878E-07 1,385E-04 ! regulation of behavior GO:0050795 43 24 4,000 3,035E-07 1,217E-04 ! response to steroid hormone stimulus GO:0048545 137 78 6,000 5,005E-07 1,72E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 6,000 5,464E-07 1,643E-04 ! positive regulation of phosphorylation GO:0042327 129 79 6,000 5,464E-07 1,461E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 6,000 6,488E-07 1,561E-04 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 6,000 7,057E-07 1,544E-04 ! regulation of ligase activity GO:0051340 142 84 6,000 8,323E-07 1,669E-04 ! endocrine pancreas development GO:0031018 22 13 3,000 9,037E-07 1,672E-04 ! positive regulation of protein modification process GO:0031401 136 88 6,000 1,143E-06 1,964E-04 ! gland development GO:0048732 206 88 6,000 1,143E-06 1,833E-04 ! leukocyte chemotaxis GO:0030595 50 33 4,000 1,621E-06 2,438E-04 GO:0060326|cell chemotaxis, ! positive regulation of chemokine production GO:0032722 8 5 2,000 2,187E-06 3,096E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 3,402E-06 4,547E-04 ! negative regulation of ligase activity GO:0051352 112 68 5,000 3,712E-06 4,701E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 5,000 3,712E-06 4,466E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 5,000 4,045E-06 4,635E-04 ! organ or tissue specific immune response GO:0002251 7 6 2,000 4,355E-06 4,763E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 5,000 5,194E-06 5,433E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 5,000 5,194E-06 5,207E-04 ! pancreas development GO:0031016 35 20 3,000 5,923E-06 5,7E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 5,923E-06 5,481E-04 ! oxaloacetate metabolic process GO:0006107 10 7 2,000 7,587E-06 6,761E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 7,587E-06 6,519E-04 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 2,000 7,587E-06 6,295E-04 GO:0002688|regulation of leukocyte chemotaxis, ! defense response to Gram-negative bacterium GO:0050829 9 7 2,000 7,587E-06 6,085E-04 ! positive regulation of ligase activity GO:0051351 124 77 5,000 7,686E-06 5,965E-04 ! leukocyte migration GO:0050900 68 45 4,000 7,867E-06 5,915E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 7,867E-06 5,736E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 8,858E-06 6,268E-04 ! response to glucocorticoid stimulus GO:0051384 38 22 3,000 8,858E-06 6,089E-04 ! positive regulation of defense response GO:0031349 76 47 4,000 9,78E-06 6,537E-04 ! regulation of inflammatory response GO:0050727 75 48 4,000 1,086E-05 7,065E-04 ! induction of apoptosis by extracellular signals GO:0008624 89 49 4,000 1,204E-05 7,623E-04 ! endocrine system development GO:0035270 104 49 4,000 1,204E-05 7,427E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,208E-05 7,269E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,208E-05 7,092E-04 ! negative regulation of transport GO:0051051 153 84 5,000 1,272E-05 7,288E-04 ! response to corticosteroid stimulus GO:0031960 41 24 3,000 1,275E-05 7,131E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,275E-05 6,969E-04 ! mitochondrion organization GO:0007005 148 86 5,000 1,457E-05 7,789E-04 ! response to estrogen stimulus GO:0043627 93 51 4,000 1,469E-05 7,682E-04 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 3,000 1,51E-05 7,73E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,776E-05 8,903E-04 GO:0045936|negative regulation of phosphate metabolic process, ! response to UV GO:0009411 104 53 4,000 1,777E-05 8,723E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,805E-05 8,684E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,805E-05 8,514E-04 ! mitochondrion localization GO:0051646 15 9 2,000 1,805E-05 8,35E-04 ! regulation of defense response GO:0031347 149 92 5,000 2,144E-05 9,732E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 5,000 2,28E-05 1,016E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,567E-05 1,123E-03 ! positive regulation of interleukin-6 production GO:0032755 14 10 2,000 2,567E-05 1,103E-03 ! protein sumoylation GO:0016925 15 10 2,000 2,567E-05 1,083E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 2,567E-05 1,065E-03 ! oocyte development GO:0048599 17 10 2,000 2,567E-05 1,047E-03 ! response to organic cyclic substance GO:0014070 55 29 3,000 2,782E-05 1,116E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,513E-05 1,386E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 3,513E-05 1,363E-03 ! oocyte differentiation GO:0009994 18 11 2,000 3,513E-05 1,342E-03 ! thymus development GO:0048538 27 11 2,000 3,513E-05 1,321E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,513E-05 1,3E-03 GO:0010829|negative regulation of glucose transport, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 3,000 3,651E-05 1,331E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 4,472E-05 1,606E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,663E-05 1,65E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 2,000 4,663E-05 1,626E-03 ! membrane protein proteolysis GO:0033619 25 12 2,000 4,663E-05 1,603E-03 GO:0006509|membrane protein ectodomain proteolysis, ! gland morphogenesis GO:0022612 29 12 2,000 4,663E-05 1,58E-03 ! spleen development GO:0048536 22 12 2,000 4,663E-05 1,558E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,663E-05 1,537E-03 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 3,000 5,305E-05 1,725E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 5,582E-05 1,791E-03 ! regulation of chemokine production GO:0032642 18 13 2,000 6,035E-05 1,911E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 6,035E-05 1,886E-03 GO:0000725|recombinational repair, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 3,000 6,674E-05 2,059E-03 ! regulation of protein stability GO:0031647 73 37 3,000 7,448E-05 2,268E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 7,647E-05 2,3E-03 ! response to gamma radiation GO:0010332 28 14 2,000 7,647E-05 2,271E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 7,647E-05 2,244E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 7,891E-05 2,287E-03 ! nucleus organization GO:0006997 67 38 3,000 8,285E-05 2,373E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 9,516E-05 2,694E-03 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 3,000 1,016E-04 2,843E-03 ! hormone-mediated signaling GO:0009755 74 41 3,000 1,121E-04 3,099E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 1,121E-04 3,064E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 1,121E-04 3,029E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,166E-04 3,117E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 2,000 1,166E-04 3,083E-03 ! response to metal ion GO:0010038 140 80 4,000 1,304E-04 3,41E-03 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 3,000 1,353E-04 3,5E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,353E-04 3,462E-03 ! regulation of viral genome replication GO:0045069 28 17 2,000 1,409E-04 3,57E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,409E-04 3,532E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,409E-04 3,496E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,409E-04 3,46E-03 ! branched chain family amino acid metabolic process GO:0009081 33 17 2,000 1,409E-04 3,425E-03 ! regulation of JAK-STAT cascade GO:0046425 70 45 3,000 1,618E-04 3,892E-03 ! positive regulation of anti-apoptosis GO:0045768 39 18 2,000 1,684E-04 4,011E-03 ! epidermis morphogenesis GO:0048730 40 18 2,000 1,684E-04 3,972E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,684E-04 3,933E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,763E-04 4,08E-03 ! pigmentation GO:0043473 100 46 3,000 1,763E-04 4,041E-03 ! response to inorganic substance GO:0010035 153 86 4,000 1,834E-04 4,163E-03 ! cellular pigmentation GO:0033059 36 19 2,000 1,991E-04 4,476E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 2,083E-04 4,64E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 2,083E-04 4,598E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 2,083E-04 4,556E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 2,27E-04 4,92E-03 ! response to alkaloid GO:0043279 38 20 2,000 2,331E-04 5,008E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,331E-04 4,964E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,331E-04 4,92E-03 ! regulation of ossification GO:0030278 117 50 3,000 2,442E-04 5,109E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 3,000 2,637E-04 5,47E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,637E-04 5,424E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 2,708E-04 5,521E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,708E-04 5,475E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,708E-04 5,429E-03 ! cell aging GO:0007569 44 21 2,000 2,708E-04 5,384E-03 ! oogenesis GO:0048477 36 21 2,000 2,708E-04 5,34E-03 ! collagen fibril organization GO:0030199 59 21 2,000 2,708E-04 5,297E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 2,708E-04 5,254E-03 ! response to cytokine stimulus GO:0034097 63 21 2,000 2,708E-04 5,212E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 2,844E-04 5,43E-03 ! positive regulation of growth GO:0045927 90 52 3,000 2,844E-04 5,387E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 2,000 3,121E-04 5,867E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,121E-04 5,822E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 3,216E-04 5,953E-03 ! regulation of protein localization GO:0032880 176 97 4,000 3,216E-04 5,907E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 3,532E-04 6,438E-03 ! aging GO:0007568 103 55 3,000 3,532E-04 6,389E-03 ! regulation of anti-apoptosis GO:0045767 53 23 2,000 3,574E-04 6,416E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 3,574E-04 6,369E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,574E-04 6,322E-03 ! regulation of viral reproduction GO:0050792 38 23 2,000 3,574E-04 6,276E-03 ! regulation of interleukin-6 production GO:0032675 29 23 2,000 3,574E-04 6,23E-03 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 3,628E-04 6,28E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,628E-04 6,235E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,628E-04 6,191E-03 ! Notch receptor processing GO:0007220 8 5 1,000 3,628E-04 6,147E-03 ! response to protozoan GO:0001562 10 5 1,000 3,628E-04 6,104E-03 ! parathyroid gland development GO:0060017 13 5 1,000 3,628E-04 6,062E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 3,628E-04 6,02E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 3,628E-04 5,979E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,628E-04 5,938E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 3,628E-04 5,898E-03 ! valine metabolic process GO:0006573 10 5 1,000 3,628E-04 5,859E-03 ! polyol catabolic process GO:0046174 7 5 1,000 3,628E-04 5,82E-03 GO:0019405|alditol catabolic process, ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 3,628E-04 5,781E-03 GO:0051489|regulation of filopodium assembly, ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,628E-04 5,743E-03 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 3,628E-04 5,705E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,628E-04 5,668E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,628E-04 5,632E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,628E-04 5,596E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,628E-04 5,56E-03 ! mitotic recombination GO:0006312 9 5 1,000 3,628E-04 5,525E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 3,628E-04 5,49E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,628E-04 5,456E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,628E-04 5,422E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,628E-04 5,388E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,628E-04 5,355E-03 ! stem cell division GO:0017145 11 5 1,000 3,628E-04 5,323E-03 GO:0048103|somatic stem cell division, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 4,052E-04 5,909E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 4,052E-04 5,873E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 4,052E-04 5,838E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 4,066E-04 5,823E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 4,066E-04 5,788E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 4,332E-04 6,131E-03 ! dicarboxylic acid metabolic process GO:0043648 42 25 2,000 4,6E-04 6,472E-03 ! cytokine-mediated signaling pathway GO:0019221 97 59 3,000 4,625E-04 6,47E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,177E-04 7,199E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 5,177E-04 7,158E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 5,253E-04 7,223E-03 ! male meiosis GO:0007140 7 6 1,000 5,42E-04 7,41E-03 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 1,000 5,42E-04 7,368E-03 ! malate metabolic process GO:0006108 11 6 1,000 5,42E-04 7,327E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 5,42E-04 7,286E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! attachment of GPI anchor to protein GO:0016255 15 6 1,000 5,42E-04 7,245E-03 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 1,000 5,42E-04 7,205E-03 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 5,42E-04 7,166E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 5,42E-04 7,127E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 9 6 1,000 5,42E-04 7,088E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 5,42E-04 7,05E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 5,42E-04 7,012E-03 ! response to UV-C GO:0010225 11 6 1,000 5,42E-04 6,974E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 5,42E-04 6,937E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 5,42E-04 6,9E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 5,42E-04 6,864E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,42E-04 6,828E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 5,589E-04 7,004E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 5,798E-04 7,228E-03 ! fat cell differentiation GO:0045444 50 27 2,000 5,798E-04 7,19E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 5,798E-04 7,153E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,798E-04 7,117E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 6,464E-04 7,895E-03 ! actin filament organization GO:0007015 148 66 3,000 7,086E-04 8,611E-03 ! extracellular matrix organization GO:0030198 133 66 3,000 7,086E-04 8,568E-03 ! tissue homeostasis GO:0001894 48 29 2,000 7,178E-04 8,635E-03 GO:0048871|multicellular organismal homeostasis, ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 7,501E-04 8,979E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 7,501E-04 8,934E-03 ! chromosome segregation GO:0007059 113 67 3,000 7,501E-04 8,89E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 7,558E-04 8,914E-03 ! prostate gland development GO:0030850 13 7 1,000 7,558E-04 8,871E-03 ! SMAD protein complex assembly GO:0007183 12 7 1,000 7,558E-04 8,828E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,558E-04 8,785E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,558E-04 8,743E-03 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 7,558E-04 8,701E-03 ! organ growth GO:0035265 15 7 1,000 7,558E-04 8,66E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 7,558E-04 8,619E-03 ! centrosome duplication GO:0051298 13 7 1,000 7,558E-04 8,578E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 7,558E-04 8,538E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 7,558E-04 8,498E-03 ! peptidyl-histidine modification GO:0018202 16 7 1,000 7,558E-04 8,458E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 7,558E-04 8,419E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 7,558E-04 8,38E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 7,558E-04 8,342E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 7,932E-04 8,714E-03 ! cell junction assembly GO:0034329 78 30 2,000 7,94E-04 8,684E-03 ! acute-phase response GO:0006953 49 30 2,000 7,94E-04 8,645E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 7,94E-04 8,606E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 7,94E-04 8,567E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 7,94E-04 8,529E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 8,381E-04 8,962E-03 ! urogenital system development GO:0001655 137 69 3,000 8,381E-04 8,922E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 8,752E-04 9,276E-03 GO:0043433|negative regulation of transcription factor activity, ! reproductive structure development GO:0048608 113 71 3,000 9,331E-04 9,847E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 9,614E-04 0,01010143 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 9,614E-04 0,01005751 ! negative regulation of transferase activity GO:0051348 140 72 3,000 9,833E-04 0,01024203 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 1,000 1,004E-03 0,0104095 ! succinate metabolic process GO:0006105 14 8 1,000 1,004E-03 0,01036482 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,004E-03 0,01032053 ! pigment granule organization GO:0048753 16 8 1,000 1,004E-03 0,01027661 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,004E-03 0,01023307 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,004E-03 0,01018989 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 1,004E-03 0,01014707 ! response to UV-B GO:0010224 16 8 1,000 1,004E-03 0,01010462 ! DNA topological change GO:0006265 12 8 1,000 1,004E-03 0,01006251 ! myeloid cell homeostasis GO:0002262 13 8 1,000 1,004E-03 0,01002076 ! blastocyst growth GO:0001832 19 8 1,000 1,004E-03 9,979E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,004E-03 9,938E-03 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 1,004E-03 9,898E-03 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 15 8 1,000 1,004E-03 9,857E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 1,004E-03 9,817E-03 ! post-embryonic development GO:0009791 69 33 2,000 1,053E-03 0,01025601 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,053E-03 0,01021466 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,089E-03 0,0105273 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 3,000 1,089E-03 0,01048519 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 3,000 1,089E-03 0,01044341 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,145E-03 0,0109364 ! meiotic cell cycle GO:0051321 122 75 3,000 1,145E-03 0,01089317 ! regulation of catabolic process GO:0009894 161 76 3,000 1,203E-03 0,01139931 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,252E-03 0,0118114 ! female gonad development GO:0008585 58 35 2,000 1,252E-03 0,01176526 ! artery development GO:0060840 24 9 1,000 1,285E-03 0,01203346 GO:0048844|artery morphogenesis, ! middle ear morphogenesis GO:0042474 14 9 1,000 1,285E-03 0,01198682 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 1,285E-03 0,01194054 ! T cell selection GO:0045058 23 9 1,000 1,285E-03 0,01189461 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,285E-03 0,01184904 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,285E-03 0,01180381 GO:0006600|creatine metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 1,285E-03 0,01175893 ! receptor clustering GO:0043113 18 9 1,000 1,285E-03 0,01171439 ! behavioral fear response GO:0001662 22 9 1,000 1,285E-03 0,01167018 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,285E-03 0,01162631 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,285E-03 0,01158277 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,285E-03 0,01153955 ! postreplication repair GO:0006301 22 9 1,000 1,285E-03 0,01149665 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,285E-03 0,01145407 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,285E-03 0,0114118 ! cell junction organization GO:0034330 86 36 2,000 1,36E-03 0,01202617 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,36E-03 0,01198212 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 1,39E-03 0,01220196 ! meiosis I GO:0007127 65 37 2,000 1,473E-03 0,01288704 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,473E-03 0,01284034 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,473E-03 0,01279399 ! development of primary female sexual characteristics GO:0046545 67 38 2,000 1,592E-03 0,01377919 GO:0046660|female sex differentiation, ! response to nutrient GO:0007584 125 82 3,000 1,595E-03 0,01375437 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,6E-03 0,01375111 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,6E-03 0,01370217 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,6E-03 0,01365359 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,6E-03 0,01360534 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,6E-03 0,01355743 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,6E-03 0,01350986 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 1,6E-03 0,01346263 ! B cell proliferation GO:0042100 18 10 1,000 1,6E-03 0,01341572 ! multicellular organism growth GO:0035264 18 10 1,000 1,6E-03 0,01336914 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,6E-03 0,01332288 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,6E-03 0,01327693 ! DNA ligation GO:0006266 19 10 1,000 1,6E-03 0,01323131 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 1,6E-03 0,013186 ! salivary gland development GO:0007431 27 10 1,000 1,6E-03 0,01314099 ! apical protein localization GO:0045176 15 10 1,000 1,6E-03 0,0130963 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 1,6E-03 0,0130519 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,6E-03 0,01300781 ! detection of calcium ion GO:0005513 23 10 1,000 1,6E-03 0,01296401 ! response to nicotine GO:0035094 20 10 1,000 1,6E-03 0,01292051 ! mammary gland development GO:0030879 86 39 2,000 1,717E-03 0,01381743 ! negative regulation of growth GO:0045926 155 84 3,000 1,743E-03 0,0139792 ! negative regulation of binding GO:0051100 72 40 2,000 1,848E-03 0,01477266 ! cytokinesis GO:0000910 72 40 2,000 1,848E-03 0,01472374 ! negative regulation of ossification GO:0030279 26 11 1,000 1,948E-03 0,01546915 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,948E-03 0,01541826 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,948E-03 0,01536771 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,948E-03 0,01531749 GO:0010812|negative regulation of cell-substrate adhesion, ! DNA methylation GO:0006306 19 11 1,000 1,948E-03 0,0152676 GO:0006305|DNA alkylation, ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 1,948E-03 0,01521803 ! germ cell migration GO:0008354 25 11 1,000 1,948E-03 0,01516878 ! cardiac cell differentiation GO:0035051 31 11 1,000 1,948E-03 0,01511985 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 1,948E-03 0,01507123 ! regulation of protein transport GO:0051223 154 87 3,000 1,983E-03 0,01528936 GO:0070201|regulation of establishment of protein localization, ! cellular amide metabolic process GO:0043603 67 41 2,000 1,985E-03 0,01525984 ! female gamete generation GO:0007292 61 41 2,000 1,985E-03 0,01521124 ! regulation of DNA binding GO:0051101 155 88 3,000 2,067E-03 0,01579057 ! response to reactive oxygen species GO:0000302 67 42 2,000 2,128E-03 0,01620546 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,128E-03 0,01615434 ! regulation of cell adhesion GO:0030155 212 89 3,000 2,154E-03 0,01630098 ! sex differentiation GO:0007548 145 90 3,000 2,244E-03 0,01692606 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,328E-03 0,0175067 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,328E-03 0,01745216 ! regulation of cell projection assembly GO:0060491 30 12 1,000 2,328E-03 0,01739796 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,328E-03 0,0173441 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,328E-03 0,01729056 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,328E-03 0,01723736 ! asymmetric protein localization GO:0008105 20 12 1,000 2,328E-03 0,01718449 ! fear response GO:0042596 26 12 1,000 2,328E-03 0,01713194 ! T cell homeostasis GO:0043029 25 12 1,000 2,328E-03 0,0170797 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,328E-03 0,01702779 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,328E-03 0,01697619 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! response to protein stimulus GO:0051789 149 91 3,000 2,336E-03 0,01698255 ! double-strand break repair GO:0006302 81 44 2,000 2,434E-03 0,01763715 ! developmental growth GO:0048589 82 44 2,000 2,434E-03 0,01758419 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,528E-03 0,01821412 ! icosanoid metabolic process GO:0006690 80 45 2,000 2,596E-03 0,01864473 ! regulation of T cell activation GO:0050863 158 94 3,000 2,628E-03 0,01882193 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,731E-03 0,01949932 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,741E-03 0,0195098 ! response to X-ray GO:0010165 25 13 1,000 2,741E-03 0,01945225 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,741E-03 0,01939504 ! exocrine system development GO:0035272 32 13 1,000 2,741E-03 0,01933816 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,741E-03 0,01928162 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 2,741E-03 0,0192254 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 2,741E-03 0,01916952 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,741E-03 0,01911395 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,765E-03 0,01922587 ! response to insulin stimulus GO:0032868 95 46 2,000 2,765E-03 0,01917046 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,765E-03 0,01911537 ! response to calcium ion GO:0051592 81 47 2,000 2,94E-03 0,02027002 ! protein homooligomerization GO:0051260 76 47 2,000 2,94E-03 0,0202121 ! interphase GO:0051325 213 98 3,000 3,056E-03 0,02094626 ! cellular component disassembly GO:0022411 86 48 2,000 3,122E-03 0,02134216 ! activation of caspase activity GO:0006919 84 48 2,000 3,122E-03 0,0212817 ! regulation of S phase GO:0033261 23 14 1,000 3,185E-03 0,02164605 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,185E-03 0,02158508 ! palate development GO:0060021 31 14 1,000 3,185E-03 0,02152444 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,185E-03 0,02146415 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,185E-03 0,0214042 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,185E-03 0,02134457 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,185E-03 0,02128528 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 3,185E-03 0,02122632 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 3,185E-03 0,02116769 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,185E-03 0,02110937 ! cell cycle arrest GO:0007050 213 100 3,000 3,286E-03 0,0217212 ! unsaturated fatty acid metabolic process GO:0033559 86 49 2,000 3,311E-03 0,0218273 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 3,311E-03 0,02176766 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,507E-03 0,02299179 ! positive regulation of cytokine production GO:0001819 86 50 2,000 3,507E-03 0,02292932 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,66E-03 0,02386547 ! positive regulation of cell size GO:0045793 27 15 1,000 3,66E-03 0,02380096 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,66E-03 0,02373681 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 3,66E-03 0,023673 ! glycoprotein catabolic process GO:0006516 26 15 1,000 3,66E-03 0,02360954 ! regulation of exocytosis GO:0017157 22 15 1,000 3,66E-03 0,02354641 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 3,66E-03 0,02348362 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,66E-03 0,02342116 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,919E-03 0,02501402 ! cartilage development GO:0051216 90 52 2,000 3,919E-03 0,02494785 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,166E-03 0,02644943 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,166E-03 0,02637982 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 4,166E-03 0,02631059 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,166E-03 0,02624171 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 4,166E-03 0,02617319 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,166E-03 0,02610503 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 2,000 4,36E-03 0,02724868 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,591E-03 0,02861905 GO:0010952|positive regulation of peptidase activity, ! regulation of multicellular organism growth GO:0040014 85 55 2,000 4,591E-03 0,02854509 ! metencephalon development GO:0022037 30 17 1,000 4,703E-03 0,02916416 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 4,703E-03 0,02908919 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,703E-03 0,0290146 ! signal complex assembly GO:0007172 41 17 1,000 4,703E-03 0,0289404 ! NAD metabolic process GO:0019674 29 17 1,000 4,703E-03 0,02886657 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,703E-03 0,02879312 ! regulation of protein binding GO:0043393 33 17 1,000 4,703E-03 0,02872004 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 4,703E-03 0,02864733 ! DNA unwinding during replication GO:0006268 27 17 1,000 4,703E-03 0,02857499 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,703E-03 0,02850301 ! nucleotide-excision repair GO:0006289 83 56 2,000 4,83E-03 0,02919772 ! regulation of DNA replication GO:0006275 101 56 2,000 4,83E-03 0,02912454 ! regulation of intracellular transport GO:0032386 101 57 2,000 5,076E-03 0,0305303 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,27E-03 0,03161975 ! centrosome cycle GO:0007098 25 18 1,000 5,27E-03 0,03154109 ! response to retinoic acid GO:0032526 26 18 1,000 5,27E-03 0,03146282 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,27E-03 0,03138495 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 5,27E-03 0,03130745 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 5,27E-03 0,03123034 ! aromatic compound catabolic process GO:0019439 27 18 1,000 5,27E-03 0,03115361 ! skeletal system morphogenesis GO:0048705 105 59 2,000 5,59E-03 0,03296233 ! DNA catabolic process GO:0006308 86 59 2,000 5,59E-03 0,03288174 ! regulation of heart contraction GO:0008016 110 60 2,000 5,858E-03 0,0343756 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 5,858E-03 0,03429196 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 5,858E-03 0,03420873 ! kidney development GO:0001822 122 60 2,000 5,858E-03 0,0341259 ! positive regulation of translation GO:0045727 30 19 1,000 5,867E-03 0,03409392 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 5,867E-03 0,03401176 ! skin development GO:0043588 36 19 1,000 5,867E-03 0,03393 ! lipid phosphorylation GO:0046834 35 19 1,000 5,867E-03 0,03384864 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,867E-03 0,03376766 ! cellular response to unfolded protein GO:0034620 33 19 1,000 5,867E-03 0,03368707 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 1,000 5,867E-03 0,03360686 ! actin filament bundle formation GO:0051017 42 19 1,000 5,867E-03 0,03352703 ! neuromuscular junction development GO:0007528 34 19 1,000 5,867E-03 0,03344759 ! prostaglandin metabolic process GO:0006693 37 19 1,000 5,867E-03 0,03336851 GO:0006692|prostanoid metabolic process, ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,867E-03 0,03328981 ! peptide hormone secretion GO:0030072 31 19 1,000 5,867E-03 0,03321149 ! ear development GO:0043583 103 62 2,000 6,417E-03 0,03624325 ! gonad development GO:0008406 98 62 2,000 6,417E-03 0,03615837 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,492E-03 0,03649737 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,492E-03 0,0364123 ! response to vitamin GO:0033273 31 20 1,000 6,492E-03 0,03632762 ! DNA duplex unwinding GO:0032508 31 20 1,000 6,492E-03 0,03624333 GO:0032392|DNA geometric change, ! peptide secretion GO:0002790 35 20 1,000 6,492E-03 0,03615943 ! detection of chemical stimulus GO:0009593 37 20 1,000 6,492E-03 0,03607592 ! peptidyl-serine modification GO:0018209 43 20 1,000 6,492E-03 0,0359928 ! leukotriene biosynthetic process GO:0019370 37 20 1,000 6,492E-03 0,03591006 GO:0043450|alkene biosynthetic process, ! regulation of mitosis GO:0007088 105 63 2,000 6,708E-03 0,03701868 GO:0051783|regulation of nuclear division, ! reciprocal meiotic recombination GO:0007131 39 21 1,000 7,147E-03 0,03935149 ! hormone secretion GO:0046879 38 21 1,000 7,147E-03 0,03926164 ! glycerol metabolic process GO:0006071 34 21 1,000 7,147E-03 0,03917221 ! ovarian follicle development GO:0001541 35 21 1,000 7,147E-03 0,03908318 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 7,147E-03 0,03899456 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 7,147E-03 0,03890633 ! DNA modification GO:0006304 34 21 1,000 7,147E-03 0,03881851 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 7,147E-03 0,03873108 ! gut development GO:0048565 39 21 1,000 7,147E-03 0,03864404 ! germ cell development GO:0007281 118 65 2,000 7,314E-03 0,03945563 ! fatty acid biosynthetic process GO:0006633 124 66 2,000 7,628E-03 0,04106037 ! secondary metabolic process GO:0019748 116 66 2,000 7,628E-03 0,04096871 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 7,831E-03 0,04196249 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 7,831E-03 0,04186924 ! regeneration GO:0031099 41 22 1,000 7,831E-03 0,0417764 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 7,831E-03 0,04168398 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,831E-03 0,04159196 ! ureteric bud development GO:0001657 43 22 1,000 7,831E-03 0,04150035 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 7,831E-03 0,04140914 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 1,000 7,831E-03 0,04131833 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,831E-03 0,04122792 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,831E-03 0,0411379 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 7,831E-03 0,04104828 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,831E-03 0,04095904 ! protein stabilization GO:0050821 39 22 1,000 7,831E-03 0,04087019 ! activation of MAPK activity GO:0000187 115 67 2,000 7,951E-03 0,04140635 ! homeostasis of number of cells GO:0048872 114 67 2,000 7,951E-03 0,04131691 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 8,543E-03 0,0442967 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,543E-03 0,04420144 ! gluconeogenesis GO:0006094 33 23 1,000 8,543E-03 0,04410658 ! response to ethanol GO:0045471 46 23 1,000 8,543E-03 0,04401214 ! leukotriene metabolic process GO:0006691 42 23 1,000 8,543E-03 0,04391809 ! platelet activation GO:0030168 37 23 1,000 8,543E-03 0,04382445 ! hormone transport GO:0009914 40 23 1,000 8,543E-03 0,04373121 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,543E-03 0,04363836 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 8,543E-03 0,04354591 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 1,000 8,543E-03 0,04345384 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 9,282E-03 0,04711656 ! multicellular organismal response to stress GO:0033555 49 24 1,000 9,282E-03 0,04701737 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 9,282E-03 0,0469186 ! lymphocyte proliferation GO:0046651 48 24 1,000 9,282E-03 0,04682023 ! cellular alkene metabolic process GO:0043449 43 24 1,000 9,282E-03 0,04672228 ! alditol metabolic process GO:0019400 38 24 1,000 9,282E-03 0,04662474 ! humoral immune response GO:0006959 109 71 2,000 9,32E-03 0,04671772 ! acute inflammatory response GO:0002526 113 72 2,000 9,683E-03 0,04843372 ! regulation of caspase activity GO:0043281 122 72 2,000 9,683E-03 0,04833323 ! myelination GO:0042552 45 25 1,000 0,01004948 0,05006012 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01004948 0,04995669 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01004948 0,04985369 ! receptor metabolic process GO:0043112 46 25 1,000 0,01004948 0,04975111 ! chromosome condensation GO:0030261 45 25 1,000 0,01004948 0,04964895 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01004948 0,04954721 ! coenzyme catabolic process GO:0009109 39 25 1,000 0,01004948 0,04944589 ! positive regulation of protein secretion GO:0050714 36 25 1,000 0,01004948 0,04934498 ! regulation of blood pressure GO:0008217 125 73 2,000 0,01005331 0,04926329 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01043207 0,05101536 ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01081901 0,05280028 ! pyruvate metabolic process GO:0006090 38 26 1,000 0,01084379 0,05281411 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 0,01084379 0,05270741 ! molting cycle process GO:0022404 50 26 1,000 0,01084379 0,05260115 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01084379 0,05249531 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01084379 0,0523899 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01084379 0,05228491 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01084379 0,05218034 ! response to estradiol stimulus GO:0032355 40 26 1,000 0,01084379 0,05207619 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01084379 0,05197245 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01084379 0,05186912 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 0,01084379 0,05176621 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01084379 0,0516637 GO:0032943|mononuclear cell proliferation, ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01121417 0,05332272 ! defense response to bacterium GO:0042742 89 76 2,000 0,01121417 0,05321755 ! neuron fate commitment GO:0048663 48 27 1,000 0,01166492 0,05524762 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,01166492 0,05513908 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01166492 0,05503096 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01166492 0,05492327 ! male gonad development GO:0008584 44 27 1,000 0,01166492 0,05481599 ! response to toxin GO:0009636 47 27 1,000 0,01166492 0,05470914 ! base-excision repair GO:0006284 41 27 1,000 0,01166492 0,0546027 ! blood coagulation GO:0007596 146 78 2,000 0,01202927 0,05619887 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 2,000 0,01202927 0,05608995 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01244925 0,05793599 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01244925 0,05782414 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01251249 0,05800588 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,01251249 0,05789433 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01251249 0,05778321 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01251249 0,05767252 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01331423 0,06125056 ! icosanoid biosynthetic process GO:0046456 54 29 1,000 0,01338617 0,06146398 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01338617 0,06134691 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01338617 0,06123028 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01338617 0,06111409 ! response to drug GO:0042493 143 82 2,000 0,01375927 0,06269848 ! regulation of innate immune response GO:0045088 51 30 1,000 0,01428561 0,06497386 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01428561 0,06485127 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 1,000 0,01428561 0,06472914 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 1,000 0,01428561 0,06460747 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01428561 0,06448625 ! response to heat GO:0009408 50 30 1,000 0,01428561 0,06436549 ! hemostasis GO:0007599 158 84 2,000 0,01467454 0,06599426 ! response to unfolded protein GO:0006986 131 85 2,000 0,0151448 0,06798208 ! alkaloid metabolic process GO:0009820 53 31 1,000 0,01521046 0,06814968 ! GPI anchor biosynthetic process GO:0006506 53 31 1,000 0,01521046 0,068023 ! ovulation cycle process GO:0022602 49 31 1,000 0,01521046 0,0678968 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01521046 0,06777107 ! peptide transport GO:0015833 55 31 1,000 0,01521046 0,0676458 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01521046 0,06752099 ! alcohol catabolic process GO:0046164 130 86 2,000 0,01562352 0,06922685 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,0161604 0,07147412 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,0161604 0,07134297 ! GPI anchor metabolic process GO:0006505 56 32 1,000 0,0161604 0,07121231 ! spindle organization GO:0007051 46 32 1,000 0,0161604 0,07108212 ! metanephros development GO:0001656 74 32 1,000 0,0161604 0,07095241 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 0,0161604 0,07082317 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,0161604 0,0706944 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,0161604 0,0705661 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,0161604 0,07043826 ! ovulation cycle GO:0042698 51 32 1,000 0,0161604 0,07031089 ! peripheral nervous system development GO:0007422 64 32 1,000 0,0161604 0,07018397 ! hindbrain development GO:0030902 61 32 1,000 0,0161604 0,07005751 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,0161604 0,06993151 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,0161604 0,06980596 ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 0,01713508 0,07388351 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01813417 0,07805153 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01813417 0,07791215 ! vitamin metabolic process GO:0006766 139 92 2,000 0,0186739 0,08008806 ! regulation of muscle development GO:0048634 70 35 1,000 0,01915734 0,08201523 ! negative regulation of secretion GO:0051048 63 35 1,000 0,01915734 0,08186955 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01915734 0,08172439 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01915734 0,08157975 ! odontogenesis GO:0042476 66 35 1,000 0,01915734 0,08143561 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01915734 0,08129199 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01921208 0,08138075 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01921208 0,08123772 ! transcription initiation GO:0006352 153 94 2,000 0,01975879 0,0834029 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02020427 0,08513392 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02020427 0,08498508 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02020427 0,08483676 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02020427 0,08468897 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02020427 0,08454168 ! aerobic respiration GO:0009060 55 36 1,000 0,02020427 0,08439491 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,02020427 0,08424864 ! detection of stimulus GO:0051606 151 96 2,000 0,02087783 0,08690666 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02127463 0,08840545 ! pigment metabolic process GO:0042440 80 37 1,000 0,02127463 0,08825302 ! response to virus GO:0009615 160 98 2,000 0,02203103 0,09123351 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,0223681 0,09247019 ! phosphoinositide biosynthetic process GO:0046489 67 38 1,000 0,0223681 0,09231158 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0223681 0,09215351 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 1,000 0,02348437 0,096587 ! ear morphogenesis GO:0042471 60 39 1,000 0,02348437 0,09642217 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02348437 0,09625791 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02348437 0,09609421 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02348437 0,09593106 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,02462312 0,10041225 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02462312 0,10024234 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02462312 0,10007302 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,02462312 0,09990426 ! T cell differentiation GO:0030217 81 41 1,000 0,02578404 0,10443838 ! polyol metabolic process GO:0019751 66 41 1,000 0,02578404 0,10426286 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02696682 0,10886271 GO:0090047|positive regulation of transcription regulator activity, ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02696682 0,10868036 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02696682 0,10849862 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02696682 0,10831748 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02817116 0,11296635 ! glucose transport GO:0015758 65 43 1,000 0,02817116 0,11277839 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02817116 0,11259105 ! hexose transport GO:0008645 67 44 1,000 0,02939675 0,11729451 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02939675 0,11710031 ! biopolymer methylation GO:0043414 84 44 1,000 0,02939675 0,11690675 ! B cell differentiation GO:0030183 107 44 1,000 0,02939675 0,11671384 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02939675 0,11652156 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02939675 0,11632991 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02939675 0,11613889 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0300165 0,11839296 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0300165 0,11819919 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0300165 0,11800606 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0300165 0,11781355 ! neuron fate determination GO:0048664 7 5 0,000 0,0300165 0,11762167 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0300165 0,11743042 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0300165 0,11723978 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0300165 0,11704977 ! polyol transport GO:0015791 12 5 0,000 0,0300165 0,11686037 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0300165 0,11667158 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0300165 0,1164834 ! response to superoxide GO:0000303 10 5 0,000 0,0300165 0,11629582 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0300165 0,11610885 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0300165 0,11592248 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0300165 0,11573671 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0300165 0,11555153 ! female meiosis GO:0007143 7 5 0,000 0,0300165 0,11536694 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0300165 0,11518295 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0300165 0,11499953 ! cobalt ion transport GO:0006824 11 5 0,000 0,0300165 0,1148167 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0300165 0,11463446 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0300165 0,11445278 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0300165 0,11427169 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0300165 0,11409116 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0300165 0,11391121 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0300165 0,11373182 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0300165 0,113553 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0300165 0,11337474 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0300165 0,11319703 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0300165 0,11301989 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0300165 0,11284329 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! negative chemotaxis GO:0050919 14 5 0,000 0,0300165 0,11266725 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0300165 0,11249176 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0300165 0,11231681 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0300165 0,1121424 ! behavioral response to pain GO:0048266 9 5 0,000 0,0300165 0,11196854 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0300165 0,11179521 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0300165 0,11162242 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0300165 0,11145017 ! micturition GO:0060073 9 5 0,000 0,0300165 0,11127844 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0300165 0,11110724 ! copulation GO:0007620 9 5 0,000 0,0300165 0,11093657 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0300165 0,11076642 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0300165 0,1105968 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0300165 0,11042769 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0300165 0,11025909 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0300165 0,11009102 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0300165 0,10992345 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0300165 0,10975639 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0300165 0,10958984 ! grooming behavior GO:0007625 6 5 0,000 0,0300165 0,1094238 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0300165 0,10925826 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0300165 0,10909321 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0300165 0,10892867 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0300165 0,10876462 ! lymph vessel development GO:0001945 10 5 0,000 0,0300165 0,10860106 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0300165 0,108438 ! endochondral ossification GO:0001958 16 5 0,000 0,0300165 0,10827542 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0300165 0,10811333 ! anagen GO:0042640 6 5 0,000 0,0300165 0,10795173 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0300165 0,10779061 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0300165 0,10762997 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0300165 0,1074698 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0300165 0,10731011 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0300165 0,1071509 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0300165 0,10699216 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0300165 0,10683389 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0300165 0,10667608 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0300165 0,10651874 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0300165 0,10636187 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0300165 0,10620545 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0300165 0,1060495 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0300165 0,105894 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0300165 0,10573896 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0300165 0,10558437 ! histidine catabolic process GO:0006548 6 5 0,000 0,0300165 0,10543023 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0300165 0,10527654 ! microvillus organization GO:0032528 7 5 0,000 0,0300165 0,1051233 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0300165 0,1049705 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0300165 0,10481815 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0300165 0,10466624 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0300165 0,10451477 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0300165 0,10436374 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0300165 0,10421314 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0300165 0,10406298 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0300165 0,10391325 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0300165 0,10376395 ! muscle cell migration GO:0014812 8 5 0,000 0,0300165 0,10361507 ! mitochondrial fission GO:0000266 8 5 0,000 0,0300165 0,10346663 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0300165 0,10331861 ! mRNA transcription GO:0009299 9 5 0,000 0,0300165 0,10317101 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0300165 0,10302383 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0300165 0,10287708 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0300165 0,10273074 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0300165 0,10258481 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0300165 0,1024393 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0300165 0,1022942 ! response to food GO:0032094 6 5 0,000 0,0300165 0,10214952 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0300165 0,10200524 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0300165 0,10186136 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0300165 0,1017179 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0300165 0,10157483 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0300165 0,10143217 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,0300165 0,10128991 ! forebrain neuron development GO:0021884 13 5 0,000 0,0300165 0,10114805 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0300165 0,10100658 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0300165 0,10086551 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0300165 0,10072484 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0300165 0,10058455 GO:0009251|glucan catabolic process, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0300165 0,10044466 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0300165 0,10030515 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0300165 0,10016603 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0300165 0,1000273 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0300165 0,09988894 ! basic amino acid transport GO:0015802 11 5 0,000 0,0300165 0,09975098 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0300165 0,09961339 ! depyrimidination GO:0045008 10 5 0,000 0,0300165 0,09947618 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0300165 0,09933935 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0300165 0,09920289 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0300165 0,09906681 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0300165 0,09893111 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0300165 0,09879577 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0300165 0,0986608 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0300165 0,0985262 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0300165 0,09839197 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0300165 0,09825811 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0300165 0,0981246 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0300165 0,09799146 ! response to arsenic GO:0046685 10 5 0,000 0,0300165 0,09785868 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0300165 0,09772626 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0300165 0,0975942 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0300165 0,09746249 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0300165 0,09733114 ! response to cadmium ion GO:0046686 7 5 0,000 0,0300165 0,09720014 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0300165 0,0970695 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0300165 0,0969392 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0300165 0,09680926 ! decidualization GO:0046697 11 5 0,000 0,0300165 0,09667966 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0300165 0,09655041 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0300165 0,0964215 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0300165 0,09629294 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0300165 0,09616472 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0300165 0,09603684 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0300165 0,09590931 ! neural tube patterning GO:0021532 7 5 0,000 0,0300165 0,09578211 ! embryonic cleavage GO:0040016 6 5 0,000 0,0300165 0,09565524 ! peroxisome fission GO:0016559 5 5 0,000 0,0300165 0,09552871 ! histone demethylation GO:0016577 10 5 0,000 0,0300165 0,09540252 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0300165 0,09527666 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0300165 0,09515113 ! metaphase plate congression GO:0051310 7 5 0,000 0,0300165 0,09502593 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0300165 0,09490106 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,0300165 0,09477652 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0300165 0,0946523 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0300165 0,09452841 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0300165 0,09440485 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0300165 0,0942816 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0300165 0,09415868 ! plasminogen activation GO:0031639 5 5 0,000 0,0300165 0,09403608 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0300165 0,09391379 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0300165 0,09379183 ! metaphase GO:0051323 8 5 0,000 0,0300165 0,09367018 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0300165 0,09354884 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0300165 0,09342782 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0300165 0,09330712 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0300165 0,09318672 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0300165 0,09306663 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0300165 0,09294686 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0300165 0,09282739 ! response to redox state GO:0051775 5 5 0,000 0,0300165 0,09270822 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0300165 0,09258937 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0300165 0,09247082 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0300165 0,09235257 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0300165 0,09223462 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0300165 0,09211697 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0300165 0,09199963 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0300165 0,09188258 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0300165 0,09176583 ! striatum development GO:0021756 9 5 0,000 0,0300165 0,09164937 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0300165 0,09153322 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0300165 0,09141735 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0300165 0,09130178 ! glial cell migration GO:0008347 11 5 0,000 0,0300165 0,0911865 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0300165 0,09107151 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0300165 0,09095681 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0300165 0,0908424 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0300165 0,09072828 ! neuroprotection GO:0043526 6 5 0,000 0,0300165 0,09061444 ! neural plate development GO:0001840 8 5 0,000 0,0300165 0,09050089 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0300165 0,09038762 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0300165 0,09027463 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0300165 0,09016193 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0300165 0,09004951 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0300165 0,08993737 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0300165 0,08982551 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0300165 0,08971392 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0300165 0,08960261 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0300165 0,08949158 ! spindle assembly GO:0051225 6 5 0,000 0,0300165 0,08938083 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0300165 0,08927034 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0300165 0,08916013 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0300165 0,08905019 ! drug metabolic process GO:0017144 6 5 0,000 0,0300165 0,08894053 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0300165 0,08883113 ! organ regeneration GO:0031100 7 5 0,000 0,0300165 0,088722 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0300165 0,08861314 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0300165 0,08850454 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0300165 0,08839621 ! glycolysis GO:0006096 65 45 1,000 0,0306433 0,09013176 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,0306433 0,09002171 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,0306433 0,08991192 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 0,0306433 0,08980241 ! cell growth GO:0016049 84 45 1,000 0,0306433 0,08969316 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,0319105 0,09328878 ! endosome transport GO:0016197 108 47 1,000 0,03319807 0,09693514 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03319807 0,09681764 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,03319807 0,09670043 ! methylation GO:0032259 90 47 1,000 0,03319807 0,0965835 ! mitochondrial transport GO:0006839 82 48 1,000 0,03450571 0,10026659 ! Notch signaling pathway GO:0007219 96 48 1,000 0,03450571 0,10014564 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,03583313 0,10387291 ! regulation of action potential GO:0001508 95 49 1,000 0,03583313 0,10374791 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03583313 0,10362321 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03583313 0,10349881 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0359114 0,1036005 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0359114 0,10347643 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0359114 0,10335265 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0359114 0,10322917 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0359114 0,10310599 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0359114 0,1029831 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0359114 0,1028605 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0359114 0,10273819 ! sleep GO:0030431 13 6 0,000 0,0359114 0,10261617 ! response to oxygen radical GO:0000305 11 6 0,000 0,0359114 0,10249444 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0359114 0,10237301 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0359114 0,10225185 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0359114 0,10213099 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0359114 0,10201041 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0359114 0,10189011 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0359114 0,1017701 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0359114 0,10165037 ! forebrain regionalization GO:0021871 8 6 0,000 0,0359114 0,10153092 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0359114 0,10141176 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0359114 0,10129287 ! response to zinc ion GO:0010043 9 6 0,000 0,0359114 0,10117426 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0359114 0,10105593 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0359114 0,10093787 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0359114 0,10082009 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0359114 0,10070258 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0359114 0,10058535 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0359114 0,10046839 ! protein refolding GO:0042026 15 6 0,000 0,0359114 0,1003517 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0359114 0,10023529 ! opsonization GO:0008228 8 6 0,000 0,0359114 0,10011914 ! mating behavior GO:0007617 7 6 0,000 0,0359114 0,10000326 ! neuron remodeling GO:0016322 15 6 0,000 0,0359114 0,09988765 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0359114 0,09977231 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0359114 0,09965723 ! equilibrioception GO:0050957 14 6 0,000 0,0359114 0,09954242 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0359114 0,09942787 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0359114 0,09931358 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0359114 0,09919956 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0359114 0,0990858 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0359114 0,0989723 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0359114 0,09885906 ! toxin metabolic process GO:0009404 11 6 0,000 0,0359114 0,09874608 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0359114 0,09863335 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0359114 0,09852089 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0359114 0,09840868 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0359114 0,09829672 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0359114 0,09818502 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0359114 0,09807357 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0359114 0,09796238 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0359114 0,09785143 ! thymic T cell selection GO:0045061 12 6 0,000 0,0359114 0,09774074 ! protein lipoylation GO:0009249 10 6 0,000 0,0359114 0,0976303 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0359114 0,09752011 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0359114 0,09741017 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0359114 0,09730047 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0359114 0,09719102 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0359114 0,09708182 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0359114 0,09697286 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0359114 0,09686414 ! response to pH GO:0009268 10 6 0,000 0,0359114 0,09675567 ! hyperosmotic response GO:0006972 9 6 0,000 0,0359114 0,09664745 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0359114 0,09653946 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0359114 0,09643172 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0359114 0,09632421 ! urea metabolic process GO:0019627 7 6 0,000 0,0359114 0,09621695 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0359114 0,09610992 ! neutrophil activation GO:0042119 8 6 0,000 0,0359114 0,09600313 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0359114 0,09589658 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0359114 0,09579026 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0359114 0,09568418 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0359114 0,09557834 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0359114 0,09547273 ! neuron apoptosis GO:0051402 9 6 0,000 0,0359114 0,09536735 ! nucleoside salvage GO:0043174 9 6 0,000 0,0359114 0,0952622 GO:0006166|purine ribonucleoside salvage, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0359114 0,09515729 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0359114 0,0950526 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0359114 0,09494815 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,0359114 0,09484393 ! carnitine transport GO:0015879 10 6 0,000 0,0359114 0,09473993 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0359114 0,09463616 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0359114 0,09453262 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0359114 0,09442931 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0359114 0,09432622 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0359114 0,09422336 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0359114 0,09412072 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0359114 0,0940183 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0359114 0,09391611 ! astrocyte development GO:0014002 15 6 0,000 0,0359114 0,09381413 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0359114 0,09371238 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0359114 0,09361085 ! interaction with symbiont GO:0051702 13 6 0,000 0,0359114 0,09350954 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0359114 0,09340845 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0359114 0,09330758 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0359114 0,09320692 ! response to copper ion GO:0046688 10 6 0,000 0,0359114 0,09310648 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0359114 0,09300626 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0359114 0,09290625 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0359114 0,09280646 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0359114 0,09270688 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0359114 0,09260752 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0359114 0,09250837 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0359114 0,09240943 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0359114 0,0923107 ! hair follicle maturation GO:0048820 7 6 0,000 0,0359114 0,09221218 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0359114 0,09211388 ! Schwann cell development GO:0014044 15 6 0,000 0,0359114 0,09201578 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0359114 0,09191789 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0359114 0,09182021 ! subpallium development GO:0021544 10 6 0,000 0,0359114 0,09172274 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0359114 0,09162547 ! histone ubiquitination GO:0016574 8 6 0,000 0,0359114 0,09152841 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0359114 0,09143155 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0359114 0,0913349 ! G2 phase GO:0051319 16 6 0,000 0,0359114 0,09123845 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0359114 0,09114221 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0359114 0,09104617 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0359114 0,09095033 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0359114 0,0908547 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0359114 0,09075926 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0359114 0,09066403 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0359114 0,09056899 ! receptor internalization GO:0031623 10 6 0,000 0,0359114 0,09047415 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0359114 0,09037952 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0359114 0,09028507 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,0359114 0,09019083 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0359114 0,09009678 ! protein destabilization GO:0031648 9 6 0,000 0,0359114 0,09000293 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0359114 0,08990928 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0359114 0,08981582 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0359114 0,08972255 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0359114 0,08962948 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0359114 0,0895366 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0359114 0,08944391 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0359114 0,08935141 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0359114 0,08925911 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0359114 0,08916699 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0359114 0,08907507 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0359114 0,08898333 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0359114 0,08889179 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0359114 0,08880043 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0359114 0,08870926 ! catecholamine transport GO:0051937 9 6 0,000 0,0359114 0,08861827 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0359114 0,08852748 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0359114 0,08843686 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0359114 0,08834644 ! maternal placenta development GO:0001893 12 6 0,000 0,0359114 0,0882562 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0359114 0,08816614 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0359114 0,08807627 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0359114 0,08798658 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0359114 0,08789707 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0359114 0,08780774 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0359114 0,0877186 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03718005 0,09072536 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03718005 0,09063344 ! positive regulation of binding GO:0051099 78 51 1,000 0,03854618 0,09386854 ! cellular amino acid biosynthetic process GO:0008652 75 51 1,000 0,03854618 0,09377363 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03854618 0,09367891 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03854618 0,09358438 ! vesicle organization GO:0016050 107 51 1,000 0,03854618 0,09349004 ! regulation of cell shape GO:0008360 125 51 1,000 0,03854618 0,09339589 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03854618 0,09330193 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03993125 0,09655738 ! synapse organization GO:0050808 85 52 1,000 0,03993125 0,09646043 ! RNA catabolic process GO:0006401 93 53 1,000 0,04133498 0,09975121 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,04133498 0,09965125 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,04133498 0,0995515 ! cell maturation GO:0048469 100 53 1,000 0,04133498 0,09945195 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04133498 0,0993526 ! tRNA transcription GO:0009304 14 7 0,000 0,04177066 0,1002996 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04177066 0,1001996 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04177066 0,1000998 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04177066 0,1000002 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04177066 0,09990079 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04177066 0,09980159 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04177066 0,09970258 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04177066 0,09960377 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04177066 0,09950515 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04177066 0,09940673 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04177066 0,0993085 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04177066 0,09921046 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04177066 0,09911262 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04177066 0,09901497 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04177066 0,09891752 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04177066 0,09882025 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04177066 0,09872318 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04177066 0,0986263 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04177066 0,09852961 ! glycolipid transport GO:0046836 10 7 0,000 0,04177066 0,0984331 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04177066 0,09833679 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04177066 0,09824066 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04177066 0,09814473 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04177066 0,09804897 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04177066 0,09795341 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04177066 0,09785803 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04177066 0,09776284 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04177066 0,09766783 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04177066 0,09757301 ! mRNA stabilization GO:0048255 18 7 0,000 0,04177066 0,09747837 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04177066 0,09738391 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04177066 0,09728964 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04177066 0,09719555 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04177066 0,09710164 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04177066 0,09700791 ! lipoprotein transport GO:0042953 14 7 0,000 0,04177066 0,09691437 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04177066 0,096821 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04177066 0,09672781 ! rhythmic behavior GO:0007622 15 7 0,000 0,04177066 0,09663481 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04177066 0,09654198 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04177066 0,09644933 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04177066 0,09635685 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04177066 0,09626456 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04177066 0,09617244 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04177066 0,0960805 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04177066 0,09598873 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04177066 0,09589714 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04177066 0,09580572 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04177066 0,09571448 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04177066 0,09562341 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04177066 0,09553251 ! spinal cord patterning GO:0021511 13 7 0,000 0,04177066 0,09544178 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04177066 0,09535123 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04177066 0,09526085 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04177066 0,09517064 ! adrenal gland development GO:0030325 17 7 0,000 0,04177066 0,0950806 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04177066 0,09499074 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04177066 0,09490104 ! ovulation GO:0030728 9 7 0,000 0,04177066 0,09481151 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04177066 0,09472215 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04177066 0,09463296 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04177066 0,09454393 ! microtubule nucleation GO:0007020 20 7 0,000 0,04177066 0,09445507 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04177066 0,09436638 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04177066 0,09427786 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04177066 0,0941895 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04177066 0,09410131 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04177066 0,09401328 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04177066 0,09392542 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04177066 0,09383772 ! galactose metabolic process GO:0006012 13 7 0,000 0,04177066 0,09375019 ! vesicle fusion GO:0006906 17 7 0,000 0,04177066 0,09366281 ! response to dietary excess GO:0002021 8 7 0,000 0,04177066 0,0935756 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04177066 0,09348856 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04177066 0,09340167 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04177066 0,09331495 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04177066 0,09322839 ! purine salvage GO:0043101 10 7 0,000 0,04177066 0,09314198 ! nucleoside transport GO:0015858 8 7 0,000 0,04177066 0,09305574 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04177066 0,09296966 ! parturition GO:0007567 14 7 0,000 0,04177066 0,09288373 ! rRNA modification GO:0000154 14 7 0,000 0,04177066 0,09279797 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04177066 0,09271236 ! spindle checkpoint GO:0031577 15 7 0,000 0,04177066 0,09262691 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04177066 0,09254162 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04177066 0,09245649 ! macrophage differentiation GO:0030225 11 7 0,000 0,04177066 0,09237151 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04177066 0,09228668 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04177066 0,09220202 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04177066 0,09211751 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04177066 0,09203315 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04177066 0,09194895 ! fibrinolysis GO:0042730 10 7 0,000 0,04177066 0,0918649 ! eating behavior GO:0042755 7 7 0,000 0,04177066 0,091781 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04177066 0,09169726 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04177066 0,09161367 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04177066 0,09153024 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04177066 0,09144695 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04177066 0,09136382 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04177066 0,09128083 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04177066 0,091198 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04177066 0,09111532 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04177066 0,09103279 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04177066 0,09095041 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04177066 0,09086817 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04177066 0,09078609 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04177066 0,09070415 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04177066 0,09062236 ! regulation of meiosis GO:0040020 12 7 0,000 0,04177066 0,09054072 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04177066 0,09045923 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04177066 0,09037788 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04177066 0,09029667 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04177066 0,09021562 ! transcription termination GO:0006353 13 7 0,000 0,04177066 0,09013471 ! response to tumor cell GO:0002347 13 7 0,000 0,04177066 0,09005394 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04177066 0,08997332 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04177066 0,08989284 ! anaphase GO:0051322 17 7 0,000 0,04177066 0,08981251 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,04177066 0,08973232 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04177066 0,08965227 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04177066 0,08957237 ! diuresis GO:0030146 12 7 0,000 0,04177066 0,08949261 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04177066 0,08941299 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04177066 0,08933351 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04177066 0,08925417 ! antibiotic transport GO:0042891 9 7 0,000 0,04177066 0,08917498 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04177066 0,08909592 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04177066 0,08901701 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04177066 0,08893823 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04177066 0,08885959 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04177066 0,08878109 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04177066 0,08870274 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04177066 0,08862451 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04177066 0,08854643 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04177066 0,08846849 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04177066 0,08839068 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04177066 0,088313 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04177066 0,08823547 ! adult feeding behavior GO:0008343 9 7 0,000 0,04177066 0,08815807 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04177066 0,08808081 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04177066 0,08800368 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04177066 0,08792668 ! muscle adaptation GO:0043500 14 7 0,000 0,04177066 0,08784982 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04177066 0,0877731 ! retina homeostasis GO:0001895 12 7 0,000 0,04177066 0,08769651 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04177066 0,08762005 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04177066 0,08754373 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04177066 0,08746754 ! protein prenylation GO:0018342 18 7 0,000 0,04177066 0,08739148 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04177066 0,08731555 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04177066 0,08723976 ! glucose catabolic process GO:0006007 82 55 1,000 0,04419729 0,09222783 ! heart morphogenesis GO:0003007 97 55 1,000 0,04419729 0,09214791 ! RNA elongation GO:0006354 79 55 1,000 0,04419729 0,09206813 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,04419729 0,09198849 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04565535 0,09494102 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04565535 0,09485904 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04565535 0,09477719 ! muscle fiber development GO:0048747 112 57 1,000 0,04713097 0,09775613 ! lipid modification GO:0030258 97 57 1,000 0,04713097 0,09767193 ! maintenance of location GO:0051235 118 57 1,000 0,04713097 0,09758788 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0475945 0,09846291 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0475945 0,09837832 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0475945 0,09829388 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0475945 0,09820958 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0475945 0,09812542 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0475945 0,09804141 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0475945 0,09795754 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0475945 0,09787382 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0475945 0,09779024 ! meiotic prophase I GO:0007128 13 8 0,000 0,0475945 0,0977068 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0475945 0,0976235 ! oligopeptide transport GO:0006857 15 8 0,000 0,0475945 0,09754035 ! UTP metabolic process GO:0046051 8 8 0,000 0,0475945 0,09745734 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0475945 0,09737446 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0475945 0,09729173 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0475945 0,09720914 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0475945 0,09712669 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0475945 0,09704438 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0475945 0,09696221 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0475945 0,09688018 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0475945 0,09679828 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0475945 0,09671653 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0475945 0,09663491 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0475945 0,09655343 ! reflex GO:0060004 16 8 0,000 0,0475945 0,09647209 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0475945 0,09639088 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0475945 0,09630982 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0475945 0,09622888 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0475945 0,09614809 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0475945 0,09606742 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0475945 0,0959869 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0475945 0,09590651 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0475945 0,09582625 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0475945 0,09574613 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0475945 0,09566614 ! histidine metabolic process GO:0006547 16 8 0,000 0,0475945 0,09558629 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0475945 0,09550656 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0475945 0,09542698 ! glycine catabolic process GO:0006546 13 8 0,000 0,0475945 0,09534752 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0475945 0,09526819 ! ER overload response GO:0006983 12 8 0,000 0,0475945 0,095189 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0475945 0,09510994 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0475945 0,09503101 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0475945 0,09495221 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0475945 0,09487355 ! macrophage activation GO:0042116 12 8 0,000 0,0475945 0,09479501 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0475945 0,0947166 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0475945 0,09463832 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0475945 0,09456017 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0475945 0,09448215 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0475945 0,09440426 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0475945 0,0943265 ! osteoblast development GO:0002076 16 8 0,000 0,0475945 0,09424886 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0475945 0,09417136 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0475945 0,09409398 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0475945 0,09401672 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0475945 0,0939396 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0475945 0,0938626 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0475945 0,09378572 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0475945 0,09370898 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0475945 0,09363235 ! intermediate filament organization GO:0045109 12 8 0,000 0,0475945 0,09355586 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0475945 0,09347949 ! cellular extravasation GO:0045123 12 8 0,000 0,0475945 0,09340324 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0475945 0,09332711 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0475945 0,09325112 ! response to antibiotic GO:0046677 11 8 0,000 0,0475945 0,09317524 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0475945 0,09309949 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0475945 0,09302386 ! response to tropane GO:0014073 15 8 0,000 0,0475945 0,09294835 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0475945 0,09287297 ! melanosome transport GO:0032402 13 8 0,000 0,0475945 0,09279771 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0475945 0,09272257 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0475945 0,09264755 ! mast cell activation GO:0045576 14 8 0,000 0,0475945 0,09257265 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0475945 0,09249788 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0475945 0,09242322 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0475945 0,09234869 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0475945 0,09227427 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0475945 0,09219998 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0475945 0,0921258 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0475945 0,09205174 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0475945 0,09197781 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0475945 0,09190399 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0475945 0,09183029 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0475945 0,09175671 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0475945 0,09168324 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0475945 0,0916099 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0475945 0,09153667 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0475945 0,09146355 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0475945 0,09139056 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0475945 0,09131768 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0475945 0,09124492 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0475945 0,09117227 ! hormone catabolic process GO:0042447 17 8 0,000 0,0475945 0,09109974 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0475945 0,09102732 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0475945 0,09095502 ! ATP catabolic process GO:0006200 11 8 0,000 0,0475945 0,09088283 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0475945 0,09081076 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0475945 0,0907388 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0475945 0,09066696 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0475945 0,09059523 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0475945 0,09052361 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0475945 0,09045211 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0475945 0,09038072 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0475945 0,09030944 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0475945 0,09023827 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0475945 0,09016722 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0475945 0,09009628 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0475945 0,09002545 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0475945 0,08995473 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0475945 0,08988412 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0475945 0,08981362 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0475945 0,08974324 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0475945 0,08967296 ! positive regulation of secretion GO:0051047 95 59 1,000 0,05013388 0,09438349 ! regulation of cellular component size GO:0032535 109 59 1,000 0,05013388 0,0943097 ! establishment of organelle localization GO:0051656 109 59 1,000 0,05013388 0,09423602 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05166064 0,09703005 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,05166064 0,09695436 ! glycerophospholipid biosynthetic process GO:0046474 105 61 1,000 0,05320392 0,0997729 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05338314 0,10003103 ! axon extension GO:0048675 15 9 0,000 0,05338314 0,09995318 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05338314 0,09987546 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05338314 0,09979786 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05338314 0,09972037 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05338314 0,09964301 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05338314 0,09956577 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05338314 0,09948865 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05338314 0,09941164 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05338314 0,09933476 ! phosphate transport GO:0006817 19 9 0,000 0,05338314 0,09925799 ! reproductive behavior GO:0019098 19 9 0,000 0,05338314 0,09918134 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05338314 0,09910482 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05338314 0,09902841 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05338314 0,09895211 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05338314 0,09887594 ! GTP metabolic process GO:0046039 9 9 0,000 0,05338314 0,09879988 ! RNA methylation GO:0001510 15 9 0,000 0,05338314 0,09872394 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05338314 0,09864811 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05338314 0,0985724 ! regulation of histone modification GO:0031056 12 9 0,000 0,05338314 0,09849681 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05338314 0,09842133 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05338314 0,09834597 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05338314 0,09827073 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05338314 0,0981956 ! chemosensory behavior GO:0007635 20 9 0,000 0,05338314 0,09812058 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05338314 0,09804568 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05338314 0,09797089 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05338314 0,09789622 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05338314 0,09782166 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05338314 0,09774722 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05338314 0,09767288 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05338314 0,09759866 ! protein targeting to ER GO:0045047 22 9 0,000 0,05338314 0,09752456 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05338314 0,09745056 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05338314 0,09737668 ! endosome organization GO:0007032 17 9 0,000 0,05338314 0,09730291 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05338314 0,09722925 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05338314 0,0971557 ! mannose metabolic process GO:0006013 13 9 0,000 0,05338314 0,09708227 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05338314 0,09700894 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05338314 0,09693573 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05338314 0,09686263 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05338314 0,09678963 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05338314 0,09671675 ! ruffle organization GO:0031529 15 9 0,000 0,05338314 0,09664397 ! retinol metabolic process GO:0042572 18 9 0,000 0,05338314 0,09657131 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05338314 0,09649875 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05338314 0,09642631 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05338314 0,09635397 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05338314 0,09628174 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05338314 0,09620962 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05338314 0,09613761 ! segment specification GO:0007379 13 9 0,000 0,05338314 0,0960657 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05338314 0,0959939 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05338314 0,09592221 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05338314 0,09585063 ! response to amine stimulus GO:0014075 13 9 0,000 0,05338314 0,09577915 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05338314 0,09570778 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05338314 0,09563652 ! erythrocyte development GO:0048821 15 9 0,000 0,05338314 0,09556536 ! gas homeostasis GO:0033483 16 9 0,000 0,05338314 0,09549431 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05338314 0,09542336 ! renal water homeostasis GO:0003091 14 9 0,000 0,05338314 0,09535252 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05338314 0,09528178 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05338314 0,09521115 ! icosanoid secretion GO:0032309 15 9 0,000 0,05338314 0,09514062 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05338314 0,0950702 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05338314 0,09499988 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05338314 0,09492967 ! regulation of cell division GO:0051302 15 9 0,000 0,05338314 0,09485956 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05338314 0,09478955 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05338314 0,09471965 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05338314 0,09464985 ! sterol catabolic process GO:0016127 11 9 0,000 0,05338314 0,09458015 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05338314 0,09451055 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05338314 0,09444106 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05338314 0,09437167 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05338314 0,09430238 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05338314 0,09423319 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05338314 0,09416411 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05338314 0,09409512 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05338314 0,09402624 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05338314 0,09395746 ! purine base metabolic process GO:0006144 21 9 0,000 0,05338314 0,09388877 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05338314 0,09382019 ! pigment granule transport GO:0051904 17 9 0,000 0,05338314 0,09375171 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05338314 0,09368333 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05338314 0,09361504 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05338314 0,09354686 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05338314 0,09347878 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,05476348 0,09582614 ! detection of external stimulus GO:0009581 91 63 1,000 0,05633906 0,09851147 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,05633906 0,09843993 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05793041 0,101147 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05793041 0,10107366 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05913679 0,10310371 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05913679 0,10302905 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05913679 0,1029545 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05913679 0,10288006 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05913679 0,10280572 ! synapsis GO:0007129 13 10 0,000 0,05913679 0,1027315 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05913679 0,10265738 ! N-glycan processing GO:0006491 20 10 0,000 0,05913679 0,10258336 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05913679 0,10250945 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05913679 0,10243565 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05913679 0,10236196 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05913679 0,10228837 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05913679 0,10221489 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05913679 0,10214151 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05913679 0,10206824 ! androgen metabolic process GO:0008209 17 10 0,000 0,05913679 0,10199507 ! phospholipid efflux GO:0033700 16 10 0,000 0,05913679 0,10192201 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05913679 0,10184905 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05913679 0,1017762 ! lung alveolus development GO:0048286 26 10 0,000 0,05913679 0,10170345 ! pathogenesis GO:0009405 13 10 0,000 0,05913679 0,1016308 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05913679 0,10155826 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05913679 0,10148582 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05913679 0,10141349 ! endoderm development GO:0007492 16 10 0,000 0,05913679 0,10134126 ! arginine catabolic process GO:0006527 13 10 0,000 0,05913679 0,10126913 ! proline metabolic process GO:0006560 13 10 0,000 0,05913679 0,1011971 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05913679 0,10112518 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05913679 0,10105335 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05913679 0,10098163 ! V(D)J recombination GO:0033151 28 10 0,000 0,05913679 0,10091002 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05913679 0,1008385 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05913679 0,10076708 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05913679 0,10069577 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05913679 0,10062456 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05913679 0,10055344 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05913679 0,10048243 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05913679 0,10041152 ! epithelial cell development GO:0002064 20 10 0,000 0,05913679 0,10034071 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05913679 0,10026999 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05913679 0,10019938 ! macroautophagy GO:0016236 17 10 0,000 0,05913679 0,10012887 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05913679 0,10005845 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05913679 0,09998814 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05913679 0,09991792 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05913679 0,09984781 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05913679 0,09977779 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05913679 0,09970786 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05913679 0,09963804 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05913679 0,09956832 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05913679 0,09949869 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05913679 0,09942916 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05913679 0,09935972 ! response to dsRNA GO:0043331 20 10 0,000 0,05913679 0,09929039 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05913679 0,09922115 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05913679 0,099152 ! melanosome localization GO:0032400 16 10 0,000 0,05913679 0,09908295 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05913679 0,099014 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05913679 0,09894515 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05913679 0,09887639 ! mRNA cleavage GO:0006379 17 10 0,000 0,05913679 0,09880772 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05913679 0,09873916 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05913679 0,09867068 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05913679 0,0986023 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05913679 0,09853402 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05913679 0,09846583 ! prophase GO:0051324 15 10 0,000 0,05913679 0,09839773 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05913679 0,09832973 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05913679 0,09826182 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,05913679 0,09819401 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05913679 0,09812629 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05913679 0,09805866 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05913679 0,09799113 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05913679 0,09792369 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05913679 0,09785634 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05913679 0,09778909 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05913679 0,09772192 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05913679 0,09765485 ! blastocyst formation GO:0001825 17 10 0,000 0,05913679 0,09758788 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05913679 0,09752099 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05913679 0,09745419 ! activation of innate immune response GO:0002218 12 10 0,000 0,05913679 0,09738749 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05913679 0,09732088 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05913679 0,09725436 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05913679 0,09718793 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05913679 0,09712159 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05913679 0,09705534 ! localization within membrane GO:0051668 20 10 0,000 0,05913679 0,09698918 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05953729 0,0975795 ! developmental maturation GO:0021700 116 66 1,000 0,06115944 0,10016992 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,06115944 0,10010177 ! hexose catabolic process GO:0019320 104 67 1,000 0,06279663 0,10271154 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,06279663 0,10264177 ! adaptive immune response GO:0002250 119 67 1,000 0,06279663 0,10257209 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06444861 0,10519902 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,06444861 0,1051277 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06485566 0,10572 ! respiratory burst GO:0045730 17 11 0,000 0,06485566 0,10564842 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06485566 0,10557694 ! neuron fate specification GO:0048665 17 11 0,000 0,06485566 0,10550556 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06485566 0,10543427 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06485566 0,10536308 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06485566 0,10529198 ! thyroid gland development GO:0030878 26 11 0,000 0,06485566 0,10522098 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06485566 0,10515008 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06485566 0,10507927 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06485566 0,10500856 ! response to pain GO:0048265 24 11 0,000 0,06485566 0,10493794 ! T cell proliferation GO:0042098 26 11 0,000 0,06485566 0,10486742 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06485566 0,10479699 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06485566 0,10472666 ! bone resorption GO:0045453 16 11 0,000 0,06485566 0,10465642 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06485566 0,10458627 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06485566 0,10451622 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06485566 0,10444626 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06485566 0,1043764 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06485566 0,10430663 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06485566 0,10423695 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06485566 0,10416737 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06485566 0,10409788 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06485566 0,10402848 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06485566 0,10395917 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06485566 0,10388996 ! lipid digestion GO:0044241 18 11 0,000 0,06485566 0,10382084 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06485566 0,10375181 ! UV protection GO:0009650 19 11 0,000 0,06485566 0,10368287 ! adult heart development GO:0007512 14 11 0,000 0,06485566 0,10361402 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06485566 0,10354527 ! temperature homeostasis GO:0001659 17 11 0,000 0,06485566 0,1034766 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06485566 0,10340803 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06485566 0,10333955 ! regulation of organ growth GO:0046620 13 11 0,000 0,06485566 0,10327116 ! pigment granule localization GO:0051875 20 11 0,000 0,06485566 0,10320286 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06485566 0,10313465 ! vasoconstriction GO:0042310 18 11 0,000 0,06485566 0,10306653 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06485566 0,10299849 ! embryonic axis specification GO:0000578 18 11 0,000 0,06485566 0,10293055 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06485566 0,1028627 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06485566 0,10279494 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06485566 0,10272727 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06485566 0,10265968 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06485566 0,10259219 ! zymogen activation GO:0031638 15 11 0,000 0,06485566 0,10252478 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06485566 0,10245747 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06485566 0,10239024 ! nucleosome positioning GO:0016584 15 11 0,000 0,06485566 0,10232309 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06485566 0,10225604 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06485566 0,10218908 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06485566 0,1021222 ! acid secretion GO:0046717 18 11 0,000 0,06485566 0,10205541 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06485566 0,10198871 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06485566 0,10192209 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06485566 0,10185556 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06485566 0,10178912 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06485566 0,10172276 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06485566 0,10165649 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06485566 0,10159031 ! embryonic gut development GO:0048566 15 11 0,000 0,06485566 0,10152422 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06485566 0,10145821 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06485566 0,10139228 ! defense response to fungus GO:0050832 13 11 0,000 0,06485566 0,10132644 ! developmental induction GO:0031128 19 11 0,000 0,06485566 0,10126069 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06485566 0,10119502 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06485566 0,10112944 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06485566 0,10106394 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06485566 0,10099852 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06485566 0,1009332 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06485566 0,10086795 ! nucleus localization GO:0051647 19 11 0,000 0,06485566 0,10080279 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06485566 0,10073771 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,06611515 0,10262777 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06611515 0,1025616 ! glycerolipid biosynthetic process GO:0045017 118 69 1,000 0,06611515 0,10249552 ! antigen processing and presentation GO:0019882 104 69 1,000 0,06611515 0,10242952 ! amine catabolic process GO:0009310 117 71 1,000 0,06949096 0,10759025 ! B cell activation GO:0042113 160 71 1,000 0,06949096 0,10752106 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06949096 0,10745196 ! regulation of immune effector process GO:0002697 137 71 1,000 0,06949096 0,10738295 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07053996 0,10893398 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07053996 0,1088641 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07053996 0,10879432 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07053996 0,10872462 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07053996 0,10865502 ! virus-host interaction GO:0019048 29 12 0,000 0,07053996 0,1085855 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07053996 0,10851607 ! cartilage condensation GO:0001502 20 12 0,000 0,07053996 0,10844673 ! mating GO:0007618 17 12 0,000 0,07053996 0,10837748 ! protein complex disassembly GO:0043241 27 12 0,000 0,07053996 0,10830832 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,07053996 0,10823924 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07053996 0,10817026 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07053996 0,10810136 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07053996 0,10803255 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07053996 0,10796383 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07053996 0,10789519 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07053996 0,10782664 ! drug transport GO:0015893 16 12 0,000 0,07053996 0,10775818 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07053996 0,10768981 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07053996 0,10762152 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07053996 0,10755332 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07053996 0,1074852 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07053996 0,10741717 ! forebrain cell migration GO:0021885 21 12 0,000 0,07053996 0,10734923 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07053996 0,10728138 ! entry into host cell GO:0030260 32 12 0,000 0,07053996 0,1072136 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,07053996 0,10714592 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07053996 0,10707832 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07053996 0,1070108 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07053996 0,10694337 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07053996 0,10687603 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07053996 0,10680877 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07053996 0,10674159 ! protein homotetramerization GO:0051289 21 12 0,000 0,07053996 0,1066745 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07053996 0,1066075 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07053996 0,10654057 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07053996 0,10647374 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07053996 0,10640698 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07053996 0,10634031 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07053996 0,10627372 ! cranial nerve development GO:0021545 20 12 0,000 0,07053996 0,10620722 ! fucose catabolic process GO:0019317 22 12 0,000 0,07053996 0,1061408 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07053996 0,10607446 ! histone acetylation GO:0016573 26 12 0,000 0,07053996 0,1060082 ! histone methylation GO:0016571 26 12 0,000 0,07053996 0,10594203 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07053996 0,10587594 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07053996 0,10580993 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07053996 0,10574401 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,07053996 0,10567817 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07053996 0,10561241 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07053996 0,10554673 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07053996 0,10548113 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07053996 0,10541561 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07053996 0,10535018 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07053996 0,10528482 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07053996 0,10521955 ! response to cold GO:0009409 17 12 0,000 0,07053996 0,10515436 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07053996 0,10508925 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07053996 0,10502422 ! carbohydrate transport GO:0008643 110 72 1,000 0,07119977 0,10594103 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,0729222 0,10843685 ! axon guidance GO:0007411 139 73 1,000 0,0729222 0,10836987 ! neurotransmitter transport GO:0006836 123 74 1,000 0,07465804 0,11088101 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,07465804 0,11081261 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,07465804 0,11074429 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07618989 0,11294693 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07618989 0,11287738 ! peroxisomal transport GO:0043574 24 13 0,000 0,07618989 0,11280792 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07618989 0,11273854 ! lipid localization GO:0010876 28 13 0,000 0,07618989 0,11266925 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07618989 0,11260004 ! organelle fusion GO:0048284 32 13 0,000 0,07618989 0,11253092 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07618989 0,11246188 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07618989 0,11239293 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07618989 0,11232406 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07618989 0,11225528 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07618989 0,11218658 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07618989 0,11211796 ! methionine metabolic process GO:0006555 27 13 0,000 0,07618989 0,11204943 ! plasma membrane organization GO:0007009 24 13 0,000 0,07618989 0,11198098 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07618989 0,11191262 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07618989 0,11184434 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07618989 0,11177614 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07618989 0,11170803 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07618989 0,11163999 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07618989 0,11157205 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07618989 0,11150418 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07618989 0,1114364 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07618989 0,11136869 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07618989 0,11130108 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07618989 0,11123354 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07618989 0,11116608 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07618989 0,11109871 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07618989 0,11103142 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07618989 0,11096421 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07618989 0,11089708 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07618989 0,11083003 ! ribosome assembly GO:0042255 17 13 0,000 0,07618989 0,11076306 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07618989 0,11069618 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07618989 0,11062937 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07618989 0,11056265 ! chromatin silencing GO:0006342 26 13 0,000 0,07618989 0,110496 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07618989 0,11042944 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07618989 0,11036296 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07618989 0,11029655 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07618989 0,11023023 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07618989 0,11016398 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07618989 0,11009782 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07618989 0,11003174 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07618989 0,10996573 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07618989 0,1098998 ! embryonic placenta development GO:0001892 23 13 0,000 0,07618989 0,10983396 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07618989 0,10976819 ! insulin secretion GO:0030073 23 13 0,000 0,07618989 0,1097025 ! actin filament polymerization GO:0030041 24 13 0,000 0,07618989 0,10963688 ! acrosome reaction GO:0007340 18 13 0,000 0,07618989 0,10957135 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07640705 0,10981802 ! rhythmic process GO:0048511 128 75 1,000 0,07640705 0,10975246 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,07640705 0,10968698 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,07816902 0,11214948 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,07994373 0,1146273 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07994373 0,11455903 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,08173095 0,1170504 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,08173095 0,11698077 ! rRNA transcription GO:0009303 25 14 0,000 0,08180566 0,11701809 ! lactation GO:0007595 26 14 0,000 0,08180566 0,11694856 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08180566 0,11687911 ! reproductive cellular process GO:0048610 20 14 0,000 0,08180566 0,11680975 ! tRNA modification GO:0006400 20 14 0,000 0,08180566 0,11674046 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08180566 0,11667126 ! water transport GO:0006833 21 14 0,000 0,08180566 0,11660215 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08180566 0,11653311 ! non-recombinational repair GO:0000726 25 14 0,000 0,08180566 0,11646416 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08180566 0,11639528 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08180566 0,11632649 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08180566 0,11625778 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08180566 0,11618915 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08180566 0,1161206 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08180566 0,11605214 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08180566 0,11598375 ! arginine metabolic process GO:0006525 17 14 0,000 0,08180566 0,11591544 ! regulation of heart rate GO:0002027 24 14 0,000 0,08180566 0,11584722 ! organic alcohol transport GO:0015850 29 14 0,000 0,08180566 0,11577907 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08180566 0,11571101 ! embryo implantation GO:0007566 30 14 0,000 0,08180566 0,11564302 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08180566 0,11557512 ! L-amino acid transport GO:0015807 30 14 0,000 0,08180566 0,11550729 ! bone mineralization GO:0030282 17 14 0,000 0,08180566 0,11543954 ! stem cell development GO:0048864 43 14 0,000 0,08180566 0,11537188 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08180566 0,11530429 ! cerebellum development GO:0021549 21 14 0,000 0,08180566 0,11523678 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08180566 0,11516935 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08180566 0,115102 ! cofactor transport GO:0051181 26 14 0,000 0,08180566 0,11503473 ! NADP metabolic process GO:0006739 24 14 0,000 0,08180566 0,11496754 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08180566 0,11490042 ! intestinal absorption GO:0050892 25 14 0,000 0,08180566 0,11483339 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08180566 0,11476643 ! oxygen transport GO:0015671 21 14 0,000 0,08180566 0,11469955 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08180566 0,11463274 ! male genitalia development GO:0030539 24 14 0,000 0,08180566 0,11456602 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08180566 0,11449937 ! regulation of axon extension GO:0030516 37 14 0,000 0,08180566 0,1144328 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08180566 0,11436631 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,08534209 0,11924104 ! muscle cell differentiation GO:0042692 159 80 1,000 0,08534209 0,11917183 ! protein import into nucleus GO:0006606 158 80 1,000 0,08534209 0,11910271 ! T cell activation GO:0042110 168 81 1,000 0,08716558 0,12157703 ! response to hypoxia GO:0001666 171 81 1,000 0,08716558 0,12150659 ! digestion GO:0007586 112 81 1,000 0,08716558 0,12143624 ! nuclear import GO:0051170 161 81 1,000 0,08716558 0,12136596 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,08716558 0,12129577 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08738748 0,12153427 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,08738748 0,12146406 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08738748 0,12139393 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08738748 0,12132388 ! copper ion transport GO:0006825 20 15 0,000 0,08738748 0,12125391 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08738748 0,12118403 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08738748 0,12111422 ! sulfate transport GO:0008272 23 15 0,000 0,08738748 0,12104449 ! response to cAMP GO:0051591 22 15 0,000 0,08738748 0,12097485 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08738748 0,12090528 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08738748 0,1208358 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08738748 0,12076639 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08738748 0,12069706 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08738748 0,12062782 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08738748 0,12055865 ! pituitary gland development GO:0021983 29 15 0,000 0,08738748 0,12048956 ! vesicle coating GO:0006901 33 15 0,000 0,08738748 0,12042055 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08738748 0,12035162 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08738748 0,12028277 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08738748 0,120214 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08738748 0,12014531 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08738748 0,12007669 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08738748 0,12000815 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08738748 0,11993969 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08738748 0,11987131 ! histone deacetylation GO:0016575 20 15 0,000 0,08738748 0,11980301 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08738748 0,11973479 ! tissue regeneration GO:0042246 26 15 0,000 0,08738748 0,11966664 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08738748 0,11959857 ! water homeostasis GO:0030104 27 15 0,000 0,08738748 0,11953058 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08738748 0,11946266 ! muscle maintenance GO:0046716 26 15 0,000 0,08738748 0,11939482 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08738748 0,11932706 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08738748 0,11925938 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08738748 0,11919177 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08738748 0,11912424 ! cell killing GO:0001906 29 15 0,000 0,08738748 0,11905679 ! detection of bacterium GO:0016045 18 15 0,000 0,08738748 0,11898941 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08738748 0,11892211 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08738748 0,11885488 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08738748 0,11878773 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08738748 0,11872066 ! peptide hormone processing GO:0016486 23 15 0,000 0,08738748 0,11865366 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08900074 0,12077596 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,08900074 0,12070788 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08900074 0,12063987 ! response to oxygen levels GO:0070482 176 83 1,000 0,09084735 0,12307361 ! regulation of lyase activity GO:0051339 160 83 1,000 0,09084735 0,12300435 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,09270523 0,12544926 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09293556 0,12569025 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09293556 0,12561963 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09293556 0,1255491 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09293556 0,12547865 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09293556 0,12540827 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09293556 0,12533798 ! bone remodeling GO:0046849 27 16 0,000 0,09293556 0,12526776 ! filopodium assembly GO:0046847 32 16 0,000 0,09293556 0,12519762 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09293556 0,12512756 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09293556 0,12505758 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09293556 0,12498767 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09293556 0,12491785 ! startle response GO:0001964 28 16 0,000 0,09293556 0,1248481 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09293556 0,12477843 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09293556 0,12470884 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09293556 0,12463932 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09293556 0,12456989 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09293556 0,12450053 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09293556 0,12443125 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09293556 0,12436204 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09293556 0,12429291 ! response to osmotic stress GO:0006970 25 16 0,000 0,09293556 0,12422386 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09293556 0,12415488 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09293556 0,12408599 ! fructose metabolic process GO:0006000 25 16 0,000 0,09293556 0,12401716 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09293556 0,12394842 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09293556 0,12387975 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09293556 0,12381116 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09293556 0,12374264 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09293556 0,1236742 ! axon cargo transport GO:0008088 43 16 0,000 0,09293556 0,12360583 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09293556 0,12353754 ! DNA replication initiation GO:0006270 27 16 0,000 0,09293556 0,12346933 ! neuron recognition GO:0008038 35 16 0,000 0,09293556 0,12340119 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09293556 0,12333312 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09293556 0,12326513 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09293556 0,12319722 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09293556 0,12312938 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09293556 0,12306161 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09293556 0,12299392 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09293556 0,1229263 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09293556 0,12285876 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09293556 0,12279129 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09293556 0,1227239 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,09457415 0,12481921 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09457415 0,12475078 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 1,000 0,09645393 0,12716064 ! tube morphogenesis GO:0035239 176 86 1,000 0,09645393 0,127091 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09834436 0,12951096 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,09834436 0,12944012 ! protein localization in nucleus GO:0034504 176 87 1,000 0,09834436 0,12936935 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09845008 0,12943765 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09845008 0,12936696 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09845008 0,12929634 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09845008 0,12922581 ! endothelial cell migration GO:0043542 28 17 0,000 0,09845008 0,12915534 ! inositol metabolic process GO:0006020 28 17 0,000 0,09845008 0,12908496 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09845008 0,12901465 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09845008 0,12894442 ! glial cell development GO:0021782 27 17 0,000 0,09845008 0,12887427 ! limbic system development GO:0021761 36 17 0,000 0,09845008 0,12880419 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09845008 0,12873419 ! adult walking behavior GO:0007628 33 17 0,000 0,09845008 0,12866426 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09845008 0,12859441 ! heart looping GO:0001947 30 17 0,000 0,09845008 0,12852463 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09845008 0,12845494 ! myoblast differentiation GO:0045445 45 17 0,000 0,09845008 0,12838531 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09845008 0,12831576 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09845008 0,12824629 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09845008 0,12817689 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09845008 0,12810757 ! glycine metabolic process GO:0006544 28 17 0,000 0,09845008 0,12803832 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,09845008 0,12796915 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09845008 0,12790005 ! membrane budding GO:0006900 37 17 0,000 0,09845008 0,12783103 ! DNA integration GO:0015074 29 17 0,000 0,09845008 0,12776208 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09845008 0,12769321 ! genitalia development GO:0048806 30 17 0,000 0,09845008 0,12762441 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09845008 0,12755568 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09845008 0,12748703 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09845008 0,12741845 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09845008 0,12734995 ! steroid catabolic process GO:0006706 31 17 0,000 0,09845008 0,12728152 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09845008 0,12721316 ! gas transport GO:0015669 25 17 0,000 0,09845008 0,12714487 ! organic cation transport GO:0015695 31 17 0,000 0,09845008 0,12707666 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09845008 0,12700853 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09845008 0,12694046 ! microspike assembly GO:0030035 36 17 0,000 0,09845008 0,12687247 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09845008 0,12680455 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09845008 0,1267367 ! cellular respiration GO:0045333 135 88 1,000 0,10024525 0,12897864 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,10215639 0,13136733 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10393127 0,13357833 ! neuron maturation GO:0042551 42 18 0,000 0,10393127 0,13350701 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10393127 0,13343577 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10393127 0,1333646 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10393127 0,13329351 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10393127 0,1332225 ! memory GO:0007613 31 18 0,000 0,10393127 0,13315156 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10393127 0,1330807 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10393127 0,13300991 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10393127 0,1329392 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10393127 0,13286856 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10393127 0,132798 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10393127 0,13272751 ! response to fungus GO:0009620 21 18 0,000 0,10393127 0,1326571 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10393127 0,13258676 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10393127 0,1325165 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10393127 0,13244631 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10393127 0,13237619 ! vitamin transport GO:0051180 27 18 0,000 0,10393127 0,13230615 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10393127 0,13223619 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10393127 0,13216629 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10393127 0,13209648 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,10393127 0,13202673 ! nerve development GO:0021675 28 18 0,000 0,10393127 0,13195706 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10393127 0,13188746 ! ossification GO:0001503 188 90 1,000 0,1040776 0,13200354 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,1040776 0,13193399 ! bone development GO:0060348 189 91 1,000 0,10600869 0,13431116 ! sterol metabolic process GO:0016125 152 91 1,000 0,10600869 0,13424047 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,10794946 0,1366262 ! protein secretion GO:0009306 39 19 0,000 0,10937931 0,1383631 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10937931 0,13829039 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10937931 0,13821776 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10937931 0,1381452 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10937931 0,13807273 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10937931 0,13800032 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10937931 0,137928 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10937931 0,13785574 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10937931 0,13778357 ! cerebral cortex development GO:0021987 36 19 0,000 0,10937931 0,13771147 ! pigmentation during development GO:0048066 41 19 0,000 0,10937931 0,13763944 ! heme metabolic process GO:0042168 36 19 0,000 0,10937931 0,13756749 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10937931 0,13749562 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10937931 0,13742382 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10937931 0,1373521 ! peptide cross-linking GO:0018149 37 19 0,000 0,10937931 0,13728045 ! protein export from nucleus GO:0006611 36 19 0,000 0,10937931 0,13720887 ! heart process GO:0003015 30 19 0,000 0,10937931 0,13713737 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10937931 0,13706595 ! visual learning GO:0008542 36 19 0,000 0,10937931 0,13699459 ! G1 phase GO:0051318 40 19 0,000 0,10937931 0,13692332 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10937931 0,13685211 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10937931 0,13678099 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10937931 0,13670993 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10937931 0,13663895 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10937931 0,13656804 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10937931 0,13649721 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10937931 0,13642645 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10937931 0,13635576 ! cilium assembly GO:0042384 37 19 0,000 0,10937931 0,13628515 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10989973 0,13686271 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,10989973 0,13679191 ! female pregnancy GO:0007565 164 94 1,000 0,11185932 0,13915901 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,11382803 0,14153501 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1147944 0,14266288 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1147944 0,14258923 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1147944 0,14251565 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1147944 0,14244215 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,1147944 0,14236873 ! cAMP metabolic process GO:0046058 36 20 0,000 0,1147944 0,14229538 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1147944 0,14222211 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,1147944 0,14214891 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1147944 0,14207579 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,1147944 0,14200274 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1147944 0,14192977 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1147944 0,14185688 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1147944 0,14178405 ! cellular response to starvation GO:0009267 33 20 0,000 0,1147944 0,14171131 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,1147944 0,14163864 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,1147944 0,14156604 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,1147944 0,14149351 ! body fluid secretion GO:0007589 31 20 0,000 0,1147944 0,14142106 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,1147944 0,14134869 ! stem cell differentiation GO:0048863 53 20 0,000 0,1147944 0,14127639 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1147944 0,14120416 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,1147944 0,14113201 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1147944 0,14105993 ! sensory perception of pain GO:0019233 30 20 0,000 0,1147944 0,14098792 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1147944 0,14091599 ! diencephalon development GO:0021536 34 20 0,000 0,1147944 0,14084413 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1147944 0,14077234 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,1147944 0,14070063 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1147944 0,14062899 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1147944 0,14055742 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,1147944 0,14048593 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1147944 0,14041451 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,1147944 0,14034316 ! actin filament-based movement GO:0030048 43 20 0,000 0,1147944 0,14027188 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1147944 0,14020068 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1147944 0,14012955 ! negative regulation of translation GO:0017148 29 20 0,000 0,1147944 0,14005849 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,1147944 0,1399875 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,1147944 0,13991658 ! leukocyte differentiation GO:0002521 202 96 1,000 0,1158057 0,14107773 ! protein ubiquitination GO:0016567 217 97 1,000 0,11779213 0,14342503 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,11978715 0,14578042 GO:0016054|organic acid catabolic process, ! regulation of cell killing GO:0031341 42 21 0,000 0,12017676 0,14618062 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12017676 0,14610676 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,12017676 0,14603297 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12017676 0,14595925 ! axis specification GO:0009798 38 21 0,000 0,12017676 0,14588561 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12017676 0,14581204 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12017676 0,14573855 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12017676 0,14566513 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,12017676 0,14559178 ! cytolysis GO:0019835 24 21 0,000 0,12017676 0,14551851 ! vasodilation GO:0042311 39 21 0,000 0,12017676 0,14544531 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12017676 0,14537218 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12017676 0,14529913 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12017676 0,14522616 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12017676 0,14515325 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12017676 0,14508042 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12017676 0,14500766 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12017676 0,14493498 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12017676 0,14486236 ! collagen catabolic process GO:0030574 28 21 0,000 0,12017676 0,14478982 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12017676 0,14471736 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,12179059 0,14658737 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,12179059 0,14651408 GO:0060538|skeletal muscle organ development, ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12552656 0,15093298 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12552656 0,15085759 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12552656 0,15078228 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12552656 0,15070704 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12552656 0,15063187 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12552656 0,15055678 ! keratinization GO:0031424 28 22 0,000 0,12552656 0,15048176 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12552656 0,15040682 ! sensory perception of taste GO:0050909 28 22 0,000 0,12552656 0,15033196 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12552656 0,15025716 ! vacuolar transport GO:0007034 36 22 0,000 0,12552656 0,15018245 ! lysosome organization GO:0007040 41 22 0,000 0,12552656 0,1501078 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12552656 0,15003323 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12552656 0,14995874 ! fucose metabolic process GO:0006004 39 22 0,000 0,12552656 0,14988432 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12552656 0,14980997 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12552656 0,1497357 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12552656 0,1496615 ! sarcomere organization GO:0045214 30 22 0,000 0,12552656 0,14958737 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12552656 0,14951332 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12552656 0,14943934 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,12552656 0,14936543 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,13084401 0,15561576 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,13084401 0,15553888 ! viral genome replication GO:0019079 41 23 0,000 0,13084401 0,15546207 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13084401 0,15538533 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13084401 0,15530867 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13084401 0,15523209 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13084401 0,15515559 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13084401 0,15507915 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13084401 0,1550028 ! visual behavior GO:0007632 42 23 0,000 0,13084401 0,15492652 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13084401 0,15485031 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13084401 0,15477418 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13084401 0,15469812 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13084401 0,15462214 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13084401 0,15454624 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13084401 0,1544704 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13084401 0,15439465 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,13084401 0,15431896 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,13084401 0,15424335 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13084401 0,15416782 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13084401 0,15409236 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13084401 0,15401697 ! fatty acid transport GO:0015908 44 23 0,000 0,13084401 0,15394165 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13084401 0,15386641 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13084401 0,15379125 ! cell-cell recognition GO:0009988 25 23 0,000 0,13084401 0,15371615 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13084401 0,15364113 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13084401 0,15356619 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,1361293 0,15969142 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1361293 0,15961359 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,1361293 0,15953585 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1361293 0,15945818 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1361293 0,15938058 ! vesicle docking GO:0048278 47 24 0,000 0,1361293 0,15930306 ! spinal cord development GO:0021510 47 24 0,000 0,1361293 0,15922562 ! vacuole organization GO:0007033 43 24 0,000 0,1361293 0,15914825 ! digestive system process GO:0022600 39 24 0,000 0,1361293 0,15907095 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1361293 0,15899373 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1361293 0,15891659 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1361293 0,15883952 ! membrane depolarization GO:0051899 39 24 0,000 0,1361293 0,15876253 ! pallium development GO:0021543 49 24 0,000 0,1361293 0,15868561 ! pentose metabolic process GO:0019321 35 24 0,000 0,1361293 0,15860876 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,1361293 0,15853199 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1361293 0,15845529 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1361293 0,15837867 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1361293 0,15830212 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1361293 0,15822565 ! regulation of amine transport GO:0051952 40 24 0,000 0,1361293 0,15814925 ! protein tetramerization GO:0051262 52 24 0,000 0,1361293 0,15807292 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,14138262 0,16409387 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14138262 0,16401475 ! phototransduction GO:0007602 33 25 0,000 0,14138262 0,16393571 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14138262 0,16385674 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,14138262 0,16377785 ! sperm motility GO:0030317 31 25 0,000 0,14138262 0,16369904 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14138262 0,1636203 ! response to starvation GO:0042594 42 25 0,000 0,14138262 0,16354163 ! osteoblast differentiation GO:0001649 60 25 0,000 0,14138262 0,16346304 ! neural crest cell development GO:0014032 54 25 0,000 0,14138262 0,16338453 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 0,000 0,14138262 0,16330609 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14138262 0,16322773 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14138262 0,16314945 ! interaction with host GO:0051701 62 25 0,000 0,14138262 0,16307123 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14138262 0,1629931 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,14138262 0,16291504 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14138262 0,16283705 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,14138262 0,16275914 ! immunoglobulin production GO:0002377 55 25 0,000 0,14138262 0,1626813 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14138262 0,16260354 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14138262 0,16252585 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,14138262 0,16244823 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14138262 0,16237069 ! telomere organization GO:0032200 43 25 0,000 0,14138262 0,16229322 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,14138262 0,16221583 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,14138262 0,16213851 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14660418 0,16804652 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14660418 0,1679665 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14660418 0,16788656 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14660418 0,16780669 ! initiation of viral infection GO:0019059 57 26 0,000 0,14660418 0,16772689 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14660418 0,16764717 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14660418 0,16756753 ! tube lumen formation GO:0035148 50 26 0,000 0,14660418 0,16748796 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14660418 0,16740847 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14660418 0,16732906 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14660418 0,16724972 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14660418 0,16717045 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14660418 0,16709126 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14660418 0,16701215 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14660418 0,16693311 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14660418 0,16685414 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14660418 0,16677525 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,15179415 0,1725977 ! iron ion transport GO:0006826 59 27 0,000 0,15179415 0,17251617 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15179415 0,17243471 ! protein amino acid acylation GO:0043543 55 27 0,000 0,15179415 0,17235334 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15179415 0,17227204 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15179415 0,17219082 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15179415 0,17210967 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15179415 0,1720286 ! autophagy GO:0006914 41 27 0,000 0,15179415 0,17194761 ! primary neural tube formation GO:0014020 51 27 0,000 0,15179415 0,17186669 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15179415 0,17178585 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15179415 0,17170509 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15179415 0,1716244 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15179415 0,17154379 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15179415 0,17146325 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15179415 0,17138279 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15695273 0,17712395 ! circadian rhythm GO:0007623 50 28 0,000 0,15695273 0,17704091 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15695273 0,17695795 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15695273 0,17687507 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15695273 0,17679226 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15695273 0,17670953 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15695273 0,17662688 ! synaptogenesis GO:0007416 42 28 0,000 0,15695273 0,1765443 ! lipid oxidation GO:0034440 43 28 0,000 0,15695273 0,17646181 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15695273 0,17637939 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15695273 0,17629704 ! translational initiation GO:0006413 65 29 0,000 0,16208011 0,18197141 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,16208011 0,18188654 ! regulation of pH GO:0006885 43 29 0,000 0,16208011 0,18180174 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16208011 0,18171703 ! catechol metabolic process GO:0009712 54 29 0,000 0,16208011 0,18163239 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16208011 0,18154783 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16208011 0,18146335 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16208011 0,18137895 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16208011 0,18129462 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,16208011 0,18121038 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16208011 0,18112621 ! detection of light stimulus GO:0009583 38 29 0,000 0,16208011 0,18104212 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,16208011 0,18095811 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,16208011 0,18087418 ! regulation of coagulation GO:0050818 46 29 0,000 0,16208011 0,18079033 ! phenol metabolic process GO:0018958 55 30 0,000 0,16717647 0,18638859 ! zinc ion transport GO:0006829 45 30 0,000 0,16717647 0,18630226 ! membrane docking GO:0022406 61 30 0,000 0,16717647 0,18621601 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16717647 0,18612984 ! myofibril assembly GO:0030239 47 30 0,000 0,16717647 0,18604375 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16717647 0,18595774 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16717647 0,1858718 ! phospholipid transport GO:0015914 51 30 0,000 0,16717647 0,18578595 ! eye morphogenesis GO:0048592 60 30 0,000 0,16717647 0,18570018 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,172242 0,1912387 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,172242 0,19115049 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,172242 0,19106236 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,172242 0,19097431 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,172242 0,19088635 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,172242 0,19079846 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,172242 0,19071066 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,172242 0,19062293 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,172242 0,19053529 ! mesoderm formation GO:0001707 69 31 0,000 0,172242 0,19044773 ! natural killer cell activation GO:0030101 45 31 0,000 0,172242 0,19036025 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,172242 0,19027285 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,172242 0,19018552 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,172242 0,19009828 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,172242 0,19001112 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17727689 0,1954758 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17727689 0,19538626 ! cholesterol transport GO:0030301 56 32 0,000 0,17727689 0,1952968 ! spliceosome assembly GO:0000245 67 32 0,000 0,17727689 0,19520742 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17727689 0,19511812 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17727689 0,1950289 ! muscle cell development GO:0055001 49 32 0,000 0,17727689 0,19493976 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17727689 0,19485071 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17727689 0,19476174 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17727689 0,19467285 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17727689 0,19458403 ! gene silencing GO:0016458 65 32 0,000 0,17727689 0,19449531 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,18228132 0,19989465 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,18228132 0,19980358 ! protein targeting to membrane GO:0006612 68 33 0,000 0,18228132 0,1997126 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,18228132 0,1996217 ! ceramide metabolic process GO:0006672 64 33 0,000 0,18228132 0,19953088 ! formation of primary germ layer GO:0001704 72 33 0,000 0,18228132 0,19944014 ! cell fate specification GO:0001708 52 33 0,000 0,18228132 0,19934948 ! sterol transport GO:0015918 57 33 0,000 0,18228132 0,19925891 ! adult locomotory behavior GO:0008344 59 33 0,000 0,18228132 0,19916842 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,18228132 0,19907801 ! glial cell differentiation GO:0010001 63 34 0,000 0,18725548 0,20441773 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18725548 0,20432503 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18725548 0,20423241 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,18725548 0,20413987 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18725548 0,20404741 ! mismatch repair GO:0006298 46 34 0,000 0,18725548 0,20395504 ! spermatid development GO:0007286 63 34 0,000 0,18725548 0,20386275 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18725548 0,20377055 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18725548 0,20367843 ! placenta development GO:0001890 53 34 0,000 0,18725548 0,20358639 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,18725548 0,20349444 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,19219954 0,20877296 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19219954 0,20867875 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,19219954 0,20858462 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,19219954 0,20849058 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,19219954 0,20839662 ! cytokine production GO:0001816 59 35 0,000 0,19219954 0,20830275 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,19219954 0,20820896 ! neural tube formation GO:0001841 67 35 0,000 0,19219954 0,20811526 ! vesicle localization GO:0051648 64 35 0,000 0,19219954 0,20802164 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19711369 0,2132444 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19711369 0,21314856 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19711369 0,21305281 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19711369 0,21295714 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19711369 0,21286156 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,19711369 0,21276606 ! embryonic organ development GO:0048568 57 36 0,000 0,19711369 0,21267065 ! RNA export from nucleus GO:0006405 56 37 0,000 0,20199811 0,21784288 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,20199811 0,21774528 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,20199811 0,21764777 ! actomyosin structure organization GO:0031032 62 37 0,000 0,20199811 0,21755034 ! organic anion transport GO:0015711 68 37 0,000 0,20199811 0,217453 ! tissue remodeling GO:0048771 76 37 0,000 0,20199811 0,21735575 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,20199811 0,21725859 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20199811 0,21716151 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20199811 0,21706452 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20199811 0,21696762 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,20199811 0,2168708 ! spermatid differentiation GO:0048515 66 37 0,000 0,20199811 0,21677407 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20685298 0,22188509 GO:0006956|complement activation, ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20685298 0,22178621 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20685298 0,22168742 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,20685298 0,22158872 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,20685298 0,2214901 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,20685298 0,22139158 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20685298 0,22129314 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20685298 0,22119478 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20685298 0,22109652 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,20685298 0,22099834 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20685298 0,22090025 ! glucan metabolic process GO:0044042 62 38 0,000 0,20685298 0,22080225 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 0,000 0,21167847 0,22585295 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21167847 0,22575283 ! segmentation GO:0035282 67 39 0,000 0,21167847 0,22565281 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21167847 0,22555288 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,21167847 0,22545303 ! RNA modification GO:0009451 57 39 0,000 0,21167847 0,22535327 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21167847 0,2252536 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21647476 0,23025565 ! feeding behavior GO:0007631 59 40 0,000 0,21647476 0,2301539 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21647476 0,23005224 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,22124203 0,23501471 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,22124203 0,234911 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,22124203 0,23480737 ! gliogenesis GO:0042063 88 41 0,000 0,22124203 0,23470384 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,22124203 0,2346004 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,22124203 0,23449706 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,22598045 0,23941389 ! regulation of tube size GO:0035150 71 42 0,000 0,22598045 0,23930852 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22598045 0,23920324 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,22598045 0,23909805 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22598045 0,23899295 ! neuron migration GO:0001764 79 42 0,000 0,22598045 0,23888794 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,23069019 0,2437596 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,23069019 0,24365259 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,23069019 0,24354568 ! neural tube development GO:0021915 77 43 0,000 0,23069019 0,24343886 ! striated muscle contraction GO:0006941 77 43 0,000 0,23069019 0,24333214 ! phagocytosis GO:0006909 90 43 0,000 0,23069019 0,2432255 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,23069019 0,24311897 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23537143 0,24794381 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23537143 0,2478353 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,24002435 0,25262405 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,24002435 0,25251359 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,24002435 0,25240322 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,24002435 0,25229296 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,2446491 0,2570418 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,2446491 0,25692961 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,2446491 0,25681751 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24924586 0,2615288 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24924586 0,26141479 ! JNK cascade GO:0007254 91 47 0,000 0,24924586 0,26130089 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24924586 0,26118708 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,2538148 0,26585912 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,2538148 0,26574343 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,2538148 0,26562784 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,2538148 0,26551235 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,25835608 0,27014548 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25835608 0,27002812 ! regulation of ion transport GO:0043269 77 49 0,000 0,25835608 0,26991087 ! peptide metabolic process GO:0006518 76 49 0,000 0,25835608 0,26979372 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25835608 0,26967668 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25835608 0,26955973 ! neuromuscular process GO:0050905 99 50 0,000 0,26286988 0,27415038 ! inner ear development GO:0048839 79 50 0,000 0,26286988 0,2740316 ! histone modification GO:0016570 91 50 0,000 0,26286988 0,27391292 ! viral infectious cycle GO:0019058 99 51 0,000 0,26735635 0,27846727 ! excretion GO:0007588 83 51 0,000 0,26735635 0,27834677 ! chromatin remodeling GO:0006338 109 51 0,000 0,26735635 0,27822638 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,26735635 0,27810609 ! membrane fusion GO:0006944 110 52 0,000 0,27181567 0,28262252 ! covalent chromatin modification GO:0016569 101 52 0,000 0,27181567 0,28250043 ! amino acid activation GO:0043038 92 52 0,000 0,27181567 0,28237846 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,27624799 0,28685916 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27624799 0,2867354 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27624799 0,28661176 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27624799 0,28648822 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,28065348 0,29093161 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,28065348 0,29080632 ! cell recognition GO:0008037 85 54 0,000 0,28065348 0,29068113 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,28065348 0,29055606 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,28065348 0,29043109 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,28065348 0,29030622 ! chloride transport GO:0006821 90 55 0,000 0,2850323 0,29470894 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,2850323 0,29458235 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,2850323 0,29445587 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,2850323 0,29432949 ! gastrulation GO:0007369 112 55 0,000 0,2850323 0,29420322 ! nuclear export GO:0051168 97 55 0,000 0,2850323 0,29407706 ! sensory perception of smell GO:0007608 80 56 0,000 0,28938461 0,2984395 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28938461 0,29831164 ! proton transport GO:0015992 94 56 0,000 0,28938461 0,29818388 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,29371056 0,30251182 ! hydrogen transport GO:0006818 97 58 0,000 0,29801033 0,3068091 ! regulation of endocytosis GO:0030100 91 58 0,000 0,29801033 0,30667787 ! adult behavior GO:0030534 99 58 0,000 0,29801033 0,30654675 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,29801033 0,30641575 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,30228406 0,31067726 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,30228406 0,3105446 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30653192 0,31477413 ! camera-type eye development GO:0043010 116 60 0,000 0,30653192 0,31463984 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,31075405 0,31883763 ! mesoderm development GO:0007498 119 61 0,000 0,31075405 0,31870172 ! tRNA processing GO:0008033 89 61 0,000 0,31075405 0,31856593 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,31075405 0,31843026 ! viral reproductive process GO:0022415 126 62 0,000 0,31495062 0,3225931 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31912177 0,32672638 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,31912177 0,3265874 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,31912177 0,32644855 ! cell redox homeostasis GO:0045454 102 64 0,000 0,32326767 0,33054909 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,32326767 0,33040867 ! single fertilization GO:0007338 75 64 0,000 0,32326767 0,33026837 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32738845 0,33433643 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,32738845 0,33419458 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32738845 0,33405285 ! cell projection assembly GO:0030031 120 66 0,000 0,33148428 0,33808868 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,33555531 0,34209579 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,33555531 0,3419509 ! lung development GO:0030324 144 67 0,000 0,33555531 0,34180613 ! activation of immune response GO:0002253 105 67 0,000 0,33555531 0,34166148 ! amino acid transport GO:0006865 125 68 0,000 0,33960168 0,34563521 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33960168 0,34548906 ! viral reproduction GO:0016032 134 68 0,000 0,33960168 0,34534304 ! regulation of lipase activity GO:0060191 130 68 0,000 0,33960168 0,34519714 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,34362354 0,34913777 ! appendage morphogenesis GO:0035107 135 70 0,000 0,34762104 0,35305033 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,34762104 0,35290136 ! appendage development GO:0048736 136 71 0,000 0,35159433 0,35678446 GO:0060173|limb development, ! respiratory system development GO:0060541 153 72 0,000 0,35554355 0,36063987 ! learning or memory GO:0007611 147 73 0,000 0,35946884 0,36446778 ! fertilization GO:0009566 90 73 0,000 0,35946884 0,36431425 ! transition metal ion transport GO:0000041 126 74 0,000 0,36337036 0,3681133 ! exocytosis GO:0006887 133 74 0,000 0,36337036 0,36795837 ! eye development GO:0001654 143 74 0,000 0,36337036 0,36780357 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36724824 0,37157244 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,37110263 0,37531439 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,37110263 0,37515669 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,37493367 0,37887039 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,38252625 0,38638042 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,38252625 0,38621828 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,38628808 0,38985282 ! inorganic anion transport GO:0015698 138 80 0,000 0,38628808 0,38968936 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,39002711 0,39329641 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,40110881 0,40430155 ! nucleosome assembly GO:0006334 122 85 0,000 0,40475803 0,40780897 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,40838514 0,41129119 ! chromatin assembly GO:0031497 124 86 0,000 0,40838514 0,4111191 ! amine transport GO:0015837 155 86 0,000 0,40838514 0,41094716 ! regulation of neurological system process GO:0031644 148 88 0,000 0,41557354 0,41800583 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,41557354 0,41783115 ! cellular defense response GO:0006968 114 89 0,000 0,4191351 0,42123603 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,42267507 0,42461638 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,42619359 0,42797236 ! nucleosome organization GO:0034728 138 92 0,000 0,42969078 0,43130413 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,43662168 0,4380783 ! forebrain development GO:0030900 188 95 0,000 0,44005566 0,44133969 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,44346882 0,44457749 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,44346882 0,44439233 ! positive regulation of immune response GO:0050778 156 96 0,000 0,44346882 0,44420732 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,44686128 0,44741916 ! hormone metabolic process GO:0042445 157 97 0,000 0,44686128 0,44723305 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,45023318 0,45042039 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,45358464 0,45358464