pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6241-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of mitochondrial membrane permeability GO:0046902 9 5 2,000 2,329E-07 5,358E-04 ! protein targeting to ER GO:0045047 19 9 2,000 1,941E-06 2,232E-03 ! cell cycle arrest GO:0007050 150 86 4,000 5,036E-06 3,861E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 8,323E-06 4,786E-03 ! neuron recognition GO:0008038 22 15 2,000 1,038E-05 4,776E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 1,851E-05 7,094E-03 ! protein tetramerization GO:0051262 39 22 2,000 3,464E-05 0,01138124 ! mitochondrial membrane organization GO:0007006 39 24 2,000 4,534E-05 0,01303466 ! mesoderm formation GO:0001707 46 28 2,000 7,278E-05 0,01859972 ! protein targeting to membrane GO:0006612 53 29 2,000 8,101E-05 0,0186329 ! formation of primary germ layer GO:0001704 48 29 2,000 8,101E-05 0,016939 ! positive regulation of glycolysis GO:0045821 11 5 1,000 8,297E-05 0,0159035 ! skeletal myofibril assembly GO:0014866 7 5 1,000 8,297E-05 0,01468015 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 8,297E-05 0,01363157 ! neuronal ion channel clustering GO:0045161 7 5 1,000 8,297E-05 0,0127228 ! muscle cell proliferation GO:0033002 8 5 1,000 8,297E-05 0,01192763 ! regulation of respiratory burst GO:0060263 8 5 1,000 8,297E-05 0,011226 ! mesoderm morphogenesis GO:0048332 49 31 2,000 9,925E-05 0,01268185 ! regulation of helicase activity GO:0051095 11 6 1,000 1,242E-04 0,01503833 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,242E-04 0,01428642 ! activation of MAPKKK activity GO:0000185 10 6 1,000 1,242E-04 0,01360611 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,242E-04 0,01298765 ! ER overload response GO:0006983 7 6 1,000 1,242E-04 0,01242297 ! male sex determination GO:0030238 9 6 1,000 1,242E-04 0,01190535 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 1,000 1,242E-04 0,01142913 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 1,242E-04 0,01098955 ! axonal fasciculation GO:0007413 9 6 1,000 1,242E-04 0,01058253 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 1,313E-04 0,01078649 ! regulation of defense response to virus by virus GO:0050690 16 7 1,000 1,736E-04 0,01376802 ! protein heterooligomerization GO:0051291 10 7 1,000 1,736E-04 0,01330909 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 1,736E-04 0,01287976 ! protein retention in ER lumen GO:0006621 12 7 1,000 1,736E-04 0,01247727 ! cardiac muscle cell differentiation GO:0055007 12 7 1,000 1,736E-04 0,01209917 ! B cell lineage commitment GO:0002326 17 7 1,000 1,736E-04 0,01174332 ! T cell lineage commitment GO:0002360 12 7 1,000 1,736E-04 0,01140779 ! response to tumor cell GO:0002347 12 7 1,000 1,736E-04 0,01109091 ! striated muscle cell differentiation GO:0051146 54 38 2,000 1,836E-04 0,01141328 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 2,31E-04 0,01398341 ! regulation of embryonic development GO:0045995 16 8 1,000 2,31E-04 0,01362486 ! mitochondrial transport GO:0006839 60 42 2,000 2,478E-04 0,01424913 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 2,659E-04 0,01491354 ! regulation of developmental growth GO:0048638 13 9 1,000 2,965E-04 0,01623606 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,965E-04 0,01585847 ! regulation of glycolysis GO:0006110 15 9 1,000 2,965E-04 0,01549805 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 2,965E-04 0,01515365 ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 2,965E-04 0,01482422 ! cell recognition GO:0008037 58 45 2,000 3,044E-04 0,01489755 ! regulation of neuron apoptosis GO:0043523 77 47 2,000 3,464E-04 0,01660054 ! gastrulation GO:0007369 73 48 2,000 3,688E-04 0,01731029 ! heart morphogenesis GO:0003007 65 48 2,000 3,688E-04 0,01696409 ! regulation of DNA replication GO:0006275 75 48 2,000 3,688E-04 0,01663146 ! COPI coating of Golgi vesicle GO:0048205 14 10 1,000 3,699E-04 0,01636158 GO:0048200|Golgi transport vesicle coating, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 3,699E-04 0,01605287 ! response to X-ray GO:0010165 16 10 1,000 3,699E-04 0,01575559 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 3,699E-04 0,01546913 ! positive regulation of neuron differentiation GO:0045666 12 10 1,000 3,699E-04 0,01519289 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 3,699E-04 0,01492635 GO:0043470|regulation of carbohydrate catabolic process, ! cardiac cell differentiation GO:0035051 16 10 1,000 3,699E-04 0,014669 ! virus-host interaction GO:0019048 17 11 1,000 4,513E-04 0,01759201 ! Golgi vesicle budding GO:0048194 17 11 1,000 4,513E-04 0,01729881 ! regulation of intracellular pH GO:0051453 17 11 1,000 4,513E-04 0,01701523 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 5,405E-04 0,02005147 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 5,405E-04 0,01973319 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 5,405E-04 0,01942486 ! peptidyl-lysine modification GO:0018205 18 12 1,000 5,405E-04 0,01912602 ! response to gamma radiation GO:0010332 20 12 1,000 5,405E-04 0,01883623 ! mesoderm development GO:0007498 76 55 2,000 5,514E-04 0,01892874 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 6,376E-04 0,02156596 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 6,376E-04 0,02125341 ! regulation of cellular pH GO:0030641 20 13 1,000 6,376E-04 0,02094979 ! regulation of axon extension GO:0030516 23 13 1,000 6,376E-04 0,02065472 ! neuron maturation GO:0042551 21 14 1,000 7,425E-04 0,02371818 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 1,000 7,425E-04 0,02339327 ! activation of MAPKK activity GO:0000186 21 14 1,000 7,425E-04 0,02307715 ! regulation of defense response to virus GO:0050688 24 14 1,000 7,425E-04 0,02276945 ! cellular response to starvation GO:0009267 21 14 1,000 7,425E-04 0,02246986 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 7,425E-04 0,02217804 ! G1/S transition checkpoint GO:0031575 33 14 1,000 7,425E-04 0,0218937 ! intermediate filament-based process GO:0045103 24 14 1,000 7,425E-04 0,02161657 ! axon cargo transport GO:0008088 27 14 1,000 7,425E-04 0,02134636 ! regulation of survival gene product expression GO:0045884 20 15 1,000 8,551E-04 0,02428098 ! vesicle coating GO:0006901 25 15 1,000 8,551E-04 0,02398487 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 8,551E-04 0,0236959 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 8,551E-04 0,0234138 ! protein oligomerization GO:0051259 100 65 2,000 8,994E-04 0,02433732 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 9,755E-04 0,02608762 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 9,755E-04 0,02578776 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 9,755E-04 0,02549472 ! protein amino acid acetylation GO:0006473 28 16 1,000 9,755E-04 0,02520826 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 1,000 1,103E-03 0,02819927 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,103E-03 0,02788939 ! membrane budding GO:0006900 29 17 1,000 1,103E-03 0,02758624 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 1,000 1,103E-03 0,02728962 ! synaptogenesis GO:0007416 24 17 1,000 1,103E-03 0,0269993 ! muscle cell differentiation GO:0042692 104 71 2,000 1,163E-03 0,02814493 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,239E-03 0,029686 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 1,239E-03 0,02937995 ! response to retinoic acid GO:0032526 25 18 1,000 1,239E-03 0,02908016 ! somitogenesis GO:0001756 24 18 1,000 1,239E-03 0,02878642 ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,239E-03 0,02849856 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 1,239E-03 0,02821639 ! mitochondrion organization GO:0007005 104 73 2,000 1,26E-03 0,02840879 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,382E-03 0,03086601 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to vitamin A GO:0033189 26 19 1,000 1,382E-03 0,03056922 ! response to starvation GO:0042594 30 19 1,000 1,382E-03 0,03027808 ! sex determination GO:0007530 29 19 1,000 1,382E-03 0,02999244 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 1,382E-03 0,02971214 ! microtubule-based transport GO:0010970 37 20 1,000 1,533E-03 0,03264688 ! response to vitamin GO:0033273 29 20 1,000 1,533E-03 0,03234737 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 1,533E-03 0,0320533 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 1,533E-03 0,03176453 ! protein amino acid acylation GO:0043543 37 21 1,000 1,691E-03 0,0347299 ! ovarian follicle development GO:0001541 30 21 1,000 1,691E-03 0,03442256 ! cell aging GO:0007569 32 21 1,000 1,691E-03 0,03412061 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 1,691E-03 0,0338239 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 1,691E-03 0,03353232 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 1,691E-03 0,03324572 GO:0060415|muscle tissue morphogenesis, ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 1,691E-03 0,03296397 ! regulation of multi-organism process GO:0043900 32 21 1,000 1,691E-03 0,03268697 ! response to protein stimulus GO:0051789 111 81 2,000 1,7E-03 0,03258719 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 1,857E-03 0,03529551 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 1,857E-03 0,03500621 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 1,857E-03 0,0347216 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 1,857E-03 0,03444159 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 1,952E-03 0,03592014 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 2,03E-03 0,03705387 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,03E-03 0,03676211 ! negative regulation of DNA replication GO:0008156 35 23 1,000 2,03E-03 0,03647491 ! vesicle targeting GO:0006903 32 23 1,000 2,03E-03 0,03619216 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,03E-03 0,03591375 ! interaction with host GO:0051701 37 23 1,000 2,03E-03 0,0356396 ! regulation of response to biotic stimulus GO:0002831 35 23 1,000 2,03E-03 0,03536961 ! skeletal muscle tissue development GO:0007519 123 87 2,000 2,086E-03 0,03608112 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 2,086E-03 0,03581186 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,21E-03 0,03765736 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 2,21E-03 0,03738047 ! negative regulation of cell development GO:0010721 56 24 1,000 2,21E-03 0,03710762 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 2,21E-03 0,03683872 ! regulation of neurogenesis GO:0050767 153 89 2,000 2,226E-03 0,03683798 ! reproductive developmental process GO:0003006 127 89 2,000 2,226E-03 0,03657486 ! protein amino acid alkylation GO:0008213 39 25 1,000 2,398E-03 0,0391172 GO:0006479|protein amino acid methylation, ! male gonad development GO:0008584 33 25 1,000 2,398E-03 0,03884173 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,398E-03 0,03857011 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 2,523E-03 0,0403011 ! regulation of pH GO:0006885 36 26 1,000 2,593E-03 0,04113128 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 2,593E-03 0,04084956 ! in utero embryonic development GO:0001701 147 96 2,000 2,761E-03 0,04320259 ! myofibril assembly GO:0030239 36 27 1,000 2,795E-03 0,04344038 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 1,000 2,795E-03 0,04314884 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 2,795E-03 0,04286118 ! positive regulation of catabolic process GO:0009896 40 28 1,000 3,005E-03 0,04576723 ! response to organic cyclic substance GO:0014070 47 28 1,000 3,005E-03 0,04546613 ! ovulation cycle process GO:0022602 41 29 1,000 3,221E-03 0,04842461 ! regulation of axonogenesis GO:0050770 51 29 1,000 3,221E-03 0,04811016 ! muscle cell development GO:0055001 38 29 1,000 3,221E-03 0,04779977 ! ovulation cycle GO:0042698 43 30 1,000 3,445E-03 0,05079115 ! regulation of microtubule-based process GO:0032886 58 30 1,000 3,445E-03 0,05046764 ! establishment of vesicle localization GO:0051650 45 30 1,000 3,445E-03 0,05014822 ! DNA damage checkpoint GO:0000077 53 31 1,000 3,676E-03 0,05317056 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 3,676E-03 0,05283824 ! maintenance of protein location in cell GO:0032507 60 31 1,000 3,676E-03 0,05251006 ! segmentation GO:0035282 41 31 1,000 3,676E-03 0,05218592 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 3,676E-03 0,05186576 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 3,913E-03 0,05488396 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 3,913E-03 0,05455133 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 3,913E-03 0,0542227 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 3,913E-03 0,05389802 ! vesicle localization GO:0051648 47 32 1,000 3,913E-03 0,0535772 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4,158E-03 0,05659097 ! actomyosin structure organization GO:0031032 43 33 1,000 4,158E-03 0,05625808 ! carbohydrate homeostasis GO:0033500 39 33 1,000 4,158E-03 0,05592909 GO:0042593|glucose homeostasis, ! female gonad development GO:0008585 49 33 1,000 4,158E-03 0,05560392 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 4,158E-03 0,05528251 ! mRNA catabolic process GO:0006402 48 34 1,000 4,41E-03 0,05829161 ! regulation of neuron projection development GO:0010975 63 34 1,000 4,41E-03 0,05795851 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 4,41E-03 0,0576292 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 4,41E-03 0,05730361 ! DNA integrity checkpoint GO:0031570 57 34 1,000 4,41E-03 0,05698168 ! neuron migration GO:0001764 46 34 1,000 4,41E-03 0,05666335 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 4,41E-03 0,05634855 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 4,41E-03 0,05603724 ! maintenance of protein location GO:0045185 65 35 1,000 4,668E-03 0,0589971 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 4,934E-03 0,0620108 GO:0090047|positive regulation of transcription regulator activity, ! development of primary female sexual characteristics GO:0046545 52 36 1,000 4,934E-03 0,06167379 GO:0046660|female sex differentiation, ! maintenance of location in cell GO:0051651 69 38 1,000 5,485E-03 0,06819423 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 5,771E-03 0,07136127 ! male sex differentiation GO:0046661 53 39 1,000 5,771E-03 0,07097966 ! synapse organization GO:0050808 55 39 1,000 5,771E-03 0,07060211 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 6,063E-03 0,07378763 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 6,063E-03 0,07339927 ! T cell differentiation GO:0030217 65 40 1,000 6,063E-03 0,07301498 ! double-strand break repair GO:0006302 67 40 1,000 6,063E-03 0,0726347 ! B cell differentiation GO:0030183 62 40 1,000 6,063E-03 0,07225835 ! positive regulation of DNA binding GO:0043388 57 41 1,000 6,363E-03 0,07543215 ! biopolymer methylation GO:0043414 62 41 1,000 6,363E-03 0,07504532 ! positive regulation of binding GO:0051099 59 43 1,000 6,981E-03 0,08191506 ! activation of caspase activity GO:0006919 65 43 1,000 6,981E-03 0,08149925 ! vesicle organization GO:0016050 79 43 1,000 6,981E-03 0,08108763 ! response to insulin stimulus GO:0032868 63 43 1,000 6,981E-03 0,08068016 ! methylation GO:0032259 64 43 1,000 6,981E-03 0,08027676 ! regulation of cell projection organization GO:0031344 83 44 1,000 7,299E-03 0,08352591 ! RNA catabolic process GO:0006401 64 45 1,000 7,625E-03 0,08681689 ! cell maturation GO:0048469 60 45 1,000 7,625E-03 0,08638922 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 7,625E-03 0,08596575 ! histone modification GO:0016570 68 46 1,000 7,957E-03 0,08926913 ! response to UV GO:0009411 75 46 1,000 7,957E-03 0,08883579 ! covalent chromatin modification GO:0016569 75 47 1,000 8,295E-03 0,09216473 ! positive regulation of caspase activity GO:0043280 72 48 1,000 8,639E-03 0,09553222 GO:0010952|positive regulation of peptidase activity, ! germ cell development GO:0007281 68 49 1,000 8,99E-03 0,0989373 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 8,99E-03 0,09846617 ! maintenance of location GO:0051235 84 49 1,000 8,99E-03 0,0979995 ! skeletal muscle fiber development GO:0048741 73 50 1,000 9,348E-03 0,10141315 ! positive regulation of growth GO:0045927 67 50 1,000 9,348E-03 0,10093704 ! muscle fiber development GO:0048747 74 51 1,000 9,711E-03 0,1043724 ! positive regulation of cell migration GO:0030335 92 51 1,000 9,711E-03 0,10388695 ! aging GO:0007568 79 52 1,000 0,01008092 0,10734317 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,01008092 0,1068485 ! establishment of organelle localization GO:0051656 85 52 1,000 0,01008092 0,10635837 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,01162146 0,12205185 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,01162146 0,12149706 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,01202179 0,1251136 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,01202179 0,12455003 GO:0048609|reproductive process in a multicellular organism, ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,01202179 0,12399151 ! developmental maturation GO:0021700 75 57 1,000 0,01202179 0,12343797 ! gonad development GO:0008406 79 57 1,000 0,01202179 0,12288936 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,01242812 0,12648082 ! viral reproductive process GO:0022415 87 58 1,000 0,01242812 0,12592364 ! activation of MAPK activity GO:0000187 84 59 1,000 0,01284041 0,12953046 ! lung development GO:0030324 94 59 1,000 0,01284041 0,12896483 ! actin filament organization GO:0007015 95 59 1,000 0,01284041 0,12840411 ! fertilization GO:0009566 68 60 1,000 0,01325864 0,13201239 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,01368275 0,13564798 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,01411273 0,13931017 ! respiratory tube development GO:0030323 99 62 1,000 0,01411273 0,13871483 ! organelle localization GO:0051640 96 62 1,000 0,01411273 0,13812455 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01450322 0,14134498 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01450322 0,14074858 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01450322 0,1401572 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01450322 0,13957077 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01450322 0,13898923 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01450322 0,13841251 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01450322 0,13784056 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01450322 0,13727331 ! sleep GO:0030431 11 5 0,000 0,01450322 0,13671072 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01450322 0,13615271 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01450322 0,13559925 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01450322 0,13505026 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01450322 0,1345057 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01450322 0,13396552 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01450322 0,13342966 ! tongue development GO:0043586 6 5 0,000 0,01450322 0,13289807 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01450322 0,13237069 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01450322 0,13184749 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01450322 0,1313284 ! cobalt ion transport GO:0006824 9 5 0,000 0,01450322 0,13081339 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01450322 0,1303024 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01450322 0,12979539 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01450322 0,1292923 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01450322 0,12879311 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01450322 0,12829775 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01450322 0,12780619 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01450322 0,12731838 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01450322 0,12683428 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01450322 0,12635384 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01450322 0,12587704 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01450322 0,12540381 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01450322 0,12493414 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01450322 0,12446796 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01450322 0,12400526 ! malate metabolic process GO:0006108 7 5 0,000 0,01450322 0,12354598 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01450322 0,12309009 ! behavioral response to pain GO:0048266 7 5 0,000 0,01450322 0,12263755 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01450322 0,12218833 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01450322 0,12174239 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01450322 0,12129969 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01450322 0,1208602 ! mating behavior GO:0007617 6 5 0,000 0,01450322 0,12042388 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01450322 0,1199907 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01450322 0,11956063 ! rhythmic behavior GO:0007622 12 5 0,000 0,01450322 0,11913362 ! copulation GO:0007620 7 5 0,000 0,01450322 0,11870966 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01450322 0,1182887 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01450322 0,11787072 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01450322 0,11745568 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01450322 0,11704356 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01450322 0,11663432 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01450322 0,11622793 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01450322 0,11582436 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01450322 0,11542358 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01450322 0,11502557 ! response to protozoan GO:0001562 9 5 0,000 0,01450322 0,11463029 ! lymph vessel development GO:0001945 7 5 0,000 0,01450322 0,11423772 ! endochondral ossification GO:0001958 12 5 0,000 0,01450322 0,11384783 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01450322 0,11346059 ! parathyroid gland development GO:0060017 8 5 0,000 0,01450322 0,11307598 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01450322 0,11269397 ! anagen GO:0042640 6 5 0,000 0,01450322 0,11231453 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01450322 0,11193763 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01450322 0,11156326 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01450322 0,11119138 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01450322 0,11082198 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01450322 0,11045502 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01450322 0,11009048 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01450322 0,10972834 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01450322 0,10936857 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01450322 0,10901116 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01450322 0,10865607 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01450322 0,10830329 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01450322 0,1079528 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01450322 0,10760456 ! ovulation GO:0030728 6 5 0,000 0,01450322 0,10725857 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01450322 0,10691479 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01450322 0,10657321 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01450322 0,1062338 ! response to pH GO:0009268 9 5 0,000 0,01450322 0,10589655 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01450322 0,10556144 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01450322 0,10522844 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01450322 0,10489753 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01450322 0,1045687 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01450322 0,10424192 ! polyol catabolic process GO:0046174 7 5 0,000 0,01450322 0,10391718 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01450322 0,10359446 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01450322 0,10327373 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01450322 0,10295498 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01450322 0,1026382 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01450322 0,10232336 ! urea metabolic process GO:0019627 6 5 0,000 0,01450322 0,10201044 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01450322 0,10169943 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01450322 0,10139032 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01450322 0,10108307 ! neutrophil activation GO:0042119 5 5 0,000 0,01450322 0,10077769 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01450322 0,10047414 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01450322 0,10017242 ! response to food GO:0032094 5 5 0,000 0,01450322 0,0998725 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01450322 0,09957437 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01450322 0,09927802 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01450322 0,09898343 ! forebrain neuron development GO:0021884 7 5 0,000 0,01450322 0,09869058 ! melanosome organization GO:0032438 7 5 0,000 0,01450322 0,09839945 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01450322 0,09811004 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01450322 0,09782233 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01450322 0,0975363 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01450322 0,09725194 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01450322 0,09696923 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01450322 0,09668816 ! nucleoside transport GO:0015858 6 5 0,000 0,01450322 0,09640871 ! nucleoside salvage GO:0043174 7 5 0,000 0,01450322 0,09613088 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01450322 0,09585464 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01450322 0,09557998 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01450322 0,0953069 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01450322 0,09503537 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01450322 0,09476538 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01450322 0,09449693 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01450322 0,09422998 ! depyrimidination GO:0045008 8 5 0,000 0,01450322 0,09396455 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01450322 0,0937006 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01450322 0,09343814 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01450322 0,09317714 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01450322 0,09291759 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01450322 0,09265948 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01450322 0,09240281 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01450322 0,09214755 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01450322 0,0918937 ! monocyte differentiation GO:0030224 8 5 0,000 0,01450322 0,09164125 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01450322 0,09139018 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01450322 0,09114048 ! centrosome duplication GO:0051298 5 5 0,000 0,01450322 0,09089214 ! response to UV-C GO:0010225 6 5 0,000 0,01450322 0,09064515 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01450322 0,0903995 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01450322 0,09015517 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01450322 0,08991217 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01450322 0,08967047 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01450322 0,08943007 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01450322 0,08919095 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01450322 0,08895311 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01450322 0,08871653 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01450322 0,08848121 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01450322 0,08824713 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01450322 0,08801429 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01450322 0,08778267 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01450322 0,08755227 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01450322 0,08732307 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01450322 0,08709508 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01450322 0,08686827 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01450322 0,08664264 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01450322 0,08641817 ! neural tube patterning GO:0021532 6 5 0,000 0,01450322 0,08619487 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01450322 0,08597272 ! histone demethylation GO:0016577 9 5 0,000 0,01450322 0,08575171 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01450322 0,08553183 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01450322 0,08531308 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01450322 0,08509545 ! enteric nervous system development GO:0048484 8 5 0,000 0,01450322 0,08487892 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01450322 0,08466349 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01450322 0,08444915 ! transcription termination GO:0006353 8 5 0,000 0,01450322 0,0842359 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01450322 0,08402371 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01450322 0,0838126 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01450322 0,08360254 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01450322 0,08339354 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01450322 0,08318557 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01450322 0,08297864 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01450322 0,08277274 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01450322 0,08256786 ! apical protein localization GO:0045176 6 5 0,000 0,01450322 0,08236399 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01450322 0,08216112 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01450322 0,08195925 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01450322 0,08175837 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01450322 0,08155847 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01450322 0,08135955 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01450322 0,08116159 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01450322 0,0809646 ! glial cell migration GO:0008347 10 5 0,000 0,01450322 0,08076856 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01450322 0,08057347 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01450322 0,08037931 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01450322 0,08018609 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01450322 0,0799938 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01450322 0,07980243 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01450322 0,07961197 ! neural plate development GO:0001840 6 5 0,000 0,01450322 0,07942242 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01450322 0,07923376 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01450322 0,07904601 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01450322 0,07885914 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01450322 0,07867315 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01450322 0,07848803 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01450322 0,07830379 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01450322 0,07812041 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01450322 0,07793788 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01450322 0,07775621 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01450322 0,07757538 ! spindle assembly GO:0051225 5 5 0,000 0,01450322 0,07739539 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01450322 0,07721624 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01450322 0,07703791 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01450322 0,0768604 ! organ regeneration GO:0031100 7 5 0,000 0,01450322 0,07668371 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01450322 0,07650783 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01450322 0,07633276 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01450322 0,07615848 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01450322 0,075985 GO:0055081|anion homeostasis, ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,01454852 0,07604907 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,01454852 0,07587663 ! viral reproduction GO:0016032 92 63 1,000 0,01454852 0,07570496 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,01499009 0,07782668 ! negative regulation of cell size GO:0045792 108 64 1,000 0,01499009 0,07765139 ! respiratory system development GO:0060541 100 64 1,000 0,01499009 0,07747689 ! reproductive structure development GO:0048608 90 65 1,000 0,01543742 0,07961 ! regulation of caspase activity GO:0043281 97 65 1,000 0,01543742 0,0794319 ! B cell activation GO:0042113 104 65 1,000 0,01543742 0,0792546 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,01589045 0,08139875 ! regulation of immune effector process GO:0002697 101 66 1,000 0,01589045 0,08121786 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,01634916 0,0833771 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,01634916 0,08319263 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,01681351 0,08536661 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,01681351 0,08517858 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,01681351 0,08499137 ! rhythmic process GO:0048511 105 68 1,000 0,01681351 0,08480499 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,01728347 0,08698462 ! response to drug GO:0042493 108 69 1,000 0,01728347 0,08679469 ! tRNA transcription GO:0009304 11 6 0,000 0,01737902 0,08708443 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01737902 0,08689511 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01737902 0,08670662 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01737902 0,08651894 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01737902 0,08633208 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01737902 0,08614602 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01737902 0,08596076 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01737902 0,08577629 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01737902 0,08559262 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01737902 0,08540973 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01737902 0,08522762 ! prostate gland development GO:0030850 9 6 0,000 0,01737902 0,08504628 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01737902 0,08486572 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01737902 0,08468591 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01737902 0,08450687 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01737902 0,08432859 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01737902 0,08415106 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01737902 0,08397427 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01737902 0,08379822 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01737902 0,08362291 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01737902 0,08344833 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01737902 0,08327448 ! neuron adhesion GO:0007158 9 6 0,000 0,01737902 0,08310136 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01737902 0,08292895 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01737902 0,08275725 ! signal peptide processing GO:0006465 8 6 0,000 0,01737902 0,08258626 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01737902 0,08241598 ! mRNA stabilization GO:0048255 15 6 0,000 0,01737902 0,0822464 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01737902 0,08207752 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01737902 0,08190933 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01737902 0,08174182 ! opsonization GO:0008228 8 6 0,000 0,01737902 0,081575 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01737902 0,08140886 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01737902 0,0812434 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01737902 0,0810786 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01737902 0,08091448 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01737902 0,08075101 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01737902 0,08058821 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01737902 0,08042606 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01737902 0,08026456 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01737902 0,08010371 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01737902 0,0799435 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01737902 0,07978394 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01737902 0,079625 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01737902 0,0794667 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01737902 0,07930903 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01737902 0,07915198 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01737902 0,07899556 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01737902 0,07883975 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01737902 0,07868455 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01737902 0,07852996 ! thymic T cell selection GO:0045061 12 6 0,000 0,01737902 0,07837598 ! protein lipoylation GO:0009249 10 6 0,000 0,01737902 0,07822261 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01737902 0,07806983 ! pigment granule organization GO:0048753 11 6 0,000 0,01737902 0,07791764 ! drug transport GO:0015893 6 6 0,000 0,01737902 0,07776605 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01737902 0,07761505 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01737902 0,07746464 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01737902 0,0773148 ! histidine metabolic process GO:0006547 6 6 0,000 0,01737902 0,07716554 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01737902 0,07701686 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01737902 0,07686875 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01737902 0,07672121 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01737902 0,07657424 ! adenohypophysis development GO:0021984 10 6 0,000 0,01737902 0,07642782 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01737902 0,07628197 ! hyperosmotic response GO:0006972 8 6 0,000 0,01737902 0,07613667 ! microtubule nucleation GO:0007020 10 6 0,000 0,01737902 0,07599192 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01737902 0,07584773 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01737902 0,07570408 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01737902 0,07556097 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01737902 0,0754184 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01737902 0,07527637 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01737902 0,07513487 ! response to dietary excess GO:0002021 7 6 0,000 0,01737902 0,07499391 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01737902 0,07485347 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01737902 0,07471355 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01737902 0,07457416 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01737902 0,07443529 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01737902 0,07429694 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01737902 0,07415909 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01737902 0,07402176 ! neuron apoptosis GO:0051402 8 6 0,000 0,01737902 0,07388494 ! organic alcohol transport GO:0015850 9 6 0,000 0,01737902 0,07374862 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01737902 0,0736128 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01737902 0,07347748 ! carnitine transport GO:0015879 8 6 0,000 0,01737902 0,07334266 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01737902 0,07320834 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01737902 0,0730745 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01737902 0,07294115 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01737902 0,07280829 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01737902 0,07267591 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01737902 0,07254401 ! parturition GO:0007567 12 6 0,000 0,01737902 0,07241259 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01737902 0,07228165 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01737902 0,07215118 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01737902 0,07202117 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01737902 0,07189164 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01737902 0,07176257 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01737902 0,07163396 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01737902 0,07150582 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01737902 0,07137813 ! macrophage differentiation GO:0030225 10 6 0,000 0,01737902 0,07125089 ! astrocyte development GO:0014002 14 6 0,000 0,01737902 0,07112411 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01737902 0,07099778 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01737902 0,0708719 ! interaction with symbiont GO:0051702 8 6 0,000 0,01737902 0,07074646 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01737902 0,07062147 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01737902 0,07049692 ! eating behavior GO:0042755 6 6 0,000 0,01737902 0,0703728 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01737902 0,07024912 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01737902 0,07012588 ! response to copper ion GO:0046688 9 6 0,000 0,01737902 0,07000307 ! DNA topological change GO:0006265 8 6 0,000 0,01737902 0,06988068 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01737902 0,06975873 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01737902 0,0696372 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01737902 0,06951609 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01737902 0,0693954 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01737902 0,06927513 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01737902 0,06915528 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01737902 0,06903584 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01737902 0,06891681 ! gas homeostasis GO:0033483 11 6 0,000 0,01737902 0,0687982 ! hair follicle maturation GO:0048820 7 6 0,000 0,01737902 0,06867999 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01737902 0,06856218 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01737902 0,06844478 ! Schwann cell development GO:0014044 14 6 0,000 0,01737902 0,06832778 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01737902 0,06821118 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01737902 0,06809498 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01737902 0,06797917 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01737902 0,06786376 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01737902 0,06774873 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01737902 0,0676341 ! histone ubiquitination GO:0016574 7 6 0,000 0,01737902 0,06751985 ! regulation of meiosis GO:0040020 10 6 0,000 0,01737902 0,06740599 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01737902 0,06729251 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01737902 0,06717941 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01737902 0,0670667 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01737902 0,06695436 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01737902 0,06684239 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01737902 0,0667308 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01737902 0,06661959 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01737902 0,06650874 ! receptor internalization GO:0031623 9 6 0,000 0,01737902 0,06639826 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01737902 0,06628815 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01737902 0,0661784 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01737902 0,06606901 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01737902 0,06595999 ! protein deubiquitination GO:0016579 8 6 0,000 0,01737902 0,06585132 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01737902 0,06574301 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01737902 0,06563506 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01737902 0,06552746 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01737902 0,06542022 ! midbrain development GO:0030901 6 6 0,000 0,01737902 0,06531332 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01737902 0,06520677 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01737902 0,06510057 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01737902 0,06499472 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01737902 0,06488921 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01737902 0,06478404 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01737902 0,06467921 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01737902 0,06457472 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01737902 0,06447057 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01737902 0,06436675 ! adult feeding behavior GO:0008343 6 6 0,000 0,01737902 0,06426327 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01737902 0,06416012 ! blastocyst growth GO:0001832 15 6 0,000 0,01737902 0,06405729 ! pigment granule transport GO:0051904 12 6 0,000 0,01737902 0,0639548 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01737902 0,06385264 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01737902 0,0637508 ! catecholamine transport GO:0051937 7 6 0,000 0,01737902 0,06364929 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01737902 0,0635481 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01737902 0,06344723 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01737902 0,06334667 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01737902 0,06324644 ! protein prenylation GO:0018342 10 6 0,000 0,01737902 0,06314653 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01737902 0,06304693 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01737902 0,06294764 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01737902 0,06284867 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01737902 0,06275 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01737902 0,06265165 ! regulation of catabolic process GO:0009894 106 70 1,000 0,01775899 0,06392124 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,01824005 0,06555016 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,0187266 0,06719374 ! response to hypoxia GO:0001666 132 72 1,000 0,0187266 0,06708907 ! response to oxygen levels GO:0070482 137 74 1,000 0,01971607 0,07052406 ! protein import into nucleus GO:0006606 118 74 1,000 0,01971607 0,07041455 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,01971607 0,07030538 ! negative regulation of growth GO:0045926 123 75 1,000 0,02021892 0,07198686 ! response to nutrient GO:0007584 104 75 1,000 0,02021892 0,0718756 ! nuclear import GO:0051170 121 75 1,000 0,02021892 0,07176468 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,02024659 0,07175218 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02024659 0,07164179 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02024659 0,07153174 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02024659 0,07142203 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02024659 0,07131266 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02024659 0,07120362 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02024659 0,07109491 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02024659 0,07098653 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02024659 0,07087849 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02024659 0,07077077 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02024659 0,07066338 ! reproductive behavior GO:0019098 12 7 0,000 0,02024659 0,07055631 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02024659 0,07044957 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02024659 0,07034315 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02024659 0,07023705 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02024659 0,07013127 ! oligopeptide transport GO:0006857 11 7 0,000 0,02024659 0,07002581 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02024659 0,06992067 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02024659 0,06981584 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02024659 0,06971132 ! RNA methylation GO:0001510 11 7 0,000 0,02024659 0,06960712 ! pericardium development GO:0060039 8 7 0,000 0,02024659 0,06950323 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02024659 0,06939965 ! fibril organization GO:0043206 13 7 0,000 0,02024659 0,06929638 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02024659 0,06919341 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02024659 0,06909075 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02024659 0,06898839 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02024659 0,06888634 ! lipoprotein transport GO:0042953 9 7 0,000 0,02024659 0,06878459 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02024659 0,06868313 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02024659 0,06858198 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02024659 0,06848112 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02024659 0,06838057 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02024659 0,0682803 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02024659 0,06818033 ! chemosensory behavior GO:0007635 9 7 0,000 0,02024659 0,06808065 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02024659 0,06798126 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02024659 0,06788216 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02024659 0,06778336 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02024659 0,06768483 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02024659 0,0675866 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02024659 0,06748864 ! reflex GO:0060004 12 7 0,000 0,02024659 0,06739098 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02024659 0,06729359 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02024659 0,06719649 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02024659 0,06709966 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02024659 0,06700312 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02024659 0,06690685 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02024659 0,06681085 ! spinal cord patterning GO:0021511 7 7 0,000 0,02024659 0,06671514 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02024659 0,06661969 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02024659 0,06652452 ! adrenal gland development GO:0030325 17 7 0,000 0,02024659 0,06642962 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02024659 0,06633499 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02024659 0,06624063 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02024659 0,06614654 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02024659 0,06605272 ! endosome organization GO:0007032 10 7 0,000 0,02024659 0,06595916 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02024659 0,06586586 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02024659 0,06577283 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02024659 0,06568006 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02024659 0,06558756 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02024659 0,06549531 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02024659 0,06540332 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02024659 0,06531159 ! galactose metabolic process GO:0006012 10 7 0,000 0,02024659 0,06522012 ! vesicle fusion GO:0006906 15 7 0,000 0,02024659 0,0651289 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02024659 0,06503794 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02024659 0,06494723 ! organ growth GO:0035265 11 7 0,000 0,02024659 0,06485678 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02024659 0,06476657 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02024659 0,06467662 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02024659 0,06458691 ! retinol metabolic process GO:0042572 9 7 0,000 0,02024659 0,06449746 ! behavioral fear response GO:0001662 13 7 0,000 0,02024659 0,06440825 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02024659 0,06431929 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02024659 0,06423057 ! rRNA modification GO:0000154 12 7 0,000 0,02024659 0,0641421 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02024659 0,06405387 ! response to UV-B GO:0010224 11 7 0,000 0,02024659 0,06396589 ! intermediate filament organization GO:0045109 11 7 0,000 0,02024659 0,06387814 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02024659 0,06379064 ! fibrinolysis GO:0042730 9 7 0,000 0,02024659 0,06370337 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02024659 0,06361635 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02024659 0,06352956 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02024659 0,063443 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02024659 0,06335669 ! response to tropane GO:0014073 13 7 0,000 0,02024659 0,0632706 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02024659 0,06318476 ! melanosome localization GO:0032400 10 7 0,000 0,02024659 0,06309914 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02024659 0,06301375 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02024659 0,0629286 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02024659 0,06284368 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02024659 0,06275898 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02024659 0,06267452 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02024659 0,06259028 ! mast cell activation GO:0045576 9 7 0,000 0,02024659 0,06250626 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02024659 0,06242247 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02024659 0,06233891 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02024659 0,06225557 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02024659 0,06217245 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02024659 0,06208955 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02024659 0,06200688 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02024659 0,06192442 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02024659 0,06184218 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02024659 0,06176017 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02024659 0,06167836 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02024659 0,06159678 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02024659 0,06151541 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02024659 0,06143425 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02024659 0,06135331 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02024659 0,06127259 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02024659 0,06119207 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02024659 0,06111177 ! diuresis GO:0030146 12 7 0,000 0,02024659 0,06103167 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02024659 0,06095179 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02024659 0,06087211 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02024659 0,06079264 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02024659 0,06071338 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02024659 0,06063433 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02024659 0,06055548 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02024659 0,06047684 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02024659 0,0603984 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02024659 0,06032016 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02024659 0,06024213 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02024659 0,0601643 ! lymph node development GO:0048535 9 7 0,000 0,02024659 0,06008666 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02024659 0,06000923 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02024659 0,059932 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02024659 0,05985497 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02024659 0,05977813 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02024659 0,05970149 ! ATP catabolic process GO:0006200 10 7 0,000 0,02024659 0,05962505 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02024659 0,0595488 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02024659 0,05947275 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02024659 0,05939689 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02024659 0,05932123 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02024659 0,05924576 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02024659 0,05917048 ! muscle adaptation GO:0043500 12 7 0,000 0,02024659 0,05909539 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02024659 0,05902049 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02024659 0,05894578 ! retina homeostasis GO:0001895 9 7 0,000 0,02024659 0,05887126 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02024659 0,05879693 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02024659 0,05872278 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02024659 0,05864882 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02024659 0,05857505 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02024659 0,05850146 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02024659 0,05842806 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02024659 0,05835484 ! response to unfolded protein GO:0006986 99 76 1,000 0,02072712 0,05966506 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,02072712 0,05959048 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,02124066 0,06099065 ! regulation of DNA binding GO:0051101 119 77 1,000 0,02124066 0,0609146 ! sex differentiation GO:0007548 105 77 1,000 0,02124066 0,06083874 ! protein ubiquitination GO:0016567 125 77 1,000 0,02124066 0,06076307 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,02124066 0,06068759 ! T cell activation GO:0042110 134 79 1,000 0,02228356 0,06358833 ! protein localization in nucleus GO:0034504 133 80 1,000 0,02281287 0,06501809 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,02281287 0,06493763 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02310596 0,06569061 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02310596 0,06560951 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02310596 0,06552862 ! axon extension GO:0048675 11 8 0,000 0,02310596 0,06544792 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02310596 0,06536741 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02310596 0,06528711 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02310596 0,065207 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02310596 0,06512709 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02310596 0,06504738 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02310596 0,06496786 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02310596 0,06488853 ! phosphate transport GO:0006817 10 8 0,000 0,02310596 0,0648094 ! N-glycan processing GO:0006491 12 8 0,000 0,02310596 0,06473046 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02310596 0,06465171 ! UTP metabolic process GO:0046051 8 8 0,000 0,02310596 0,06457316 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02310596 0,06449479 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02310596 0,06441661 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02310596 0,06433863 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02310596 0,06426083 ! succinate metabolic process GO:0006105 14 8 0,000 0,02310596 0,06418322 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02310596 0,0641058 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02310596 0,06402856 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02310596 0,06395151 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02310596 0,06387465 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02310596 0,06379797 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02310596 0,06372147 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02310596 0,06364516 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02310596 0,06356903 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02310596 0,06349308 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02310596 0,06341731 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02310596 0,06334172 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02310596 0,06326632 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02310596 0,06319109 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02310596 0,06311604 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02310596 0,06304117 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02310596 0,06296648 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02310596 0,06289196 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,02310596 0,06281762 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02310596 0,06274346 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02310596 0,06266947 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02310596 0,06259565 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02310596 0,06252201 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02310596 0,06244854 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02310596 0,06237524 ! melanin metabolic process GO:0006582 12 8 0,000 0,02310596 0,06230212 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02310596 0,06222917 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02310596 0,06215638 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02310596 0,06208377 ! macrophage activation GO:0042116 12 8 0,000 0,02310596 0,06201133 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02310596 0,06193905 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02310596 0,06186695 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02310596 0,06179501 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02310596 0,06172324 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02310596 0,06165163 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02310596 0,06158019 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02310596 0,06150892 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02310596 0,06143781 ! ruffle organization GO:0031529 11 8 0,000 0,02310596 0,06136687 ! osteoblast development GO:0002076 13 8 0,000 0,02310596 0,06129609 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02310596 0,06122547 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02310596 0,06115501 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02310596 0,06108472 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02310596 0,06101459 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02310596 0,06094462 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02310596 0,06087481 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02310596 0,06080516 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02310596 0,06073567 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02310596 0,06066633 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02310596 0,06059716 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02310596 0,06052814 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02310596 0,06045928 ! segment specification GO:0007379 10 8 0,000 0,02310596 0,06039058 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02310596 0,06032203 ! cellular extravasation GO:0045123 11 8 0,000 0,02310596 0,06025364 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02310596 0,0601854 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02310596 0,06011732 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02310596 0,06004939 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02310596 0,05998161 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02310596 0,05991399 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,02310596 0,05984652 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02310596 0,0597792 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02310596 0,05971203 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02310596 0,05964501 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02310596 0,05957815 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02310596 0,05951143 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02310596 0,05944486 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02310596 0,05937844 ! icosanoid secretion GO:0032309 12 8 0,000 0,02310596 0,05931217 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02310596 0,05924605 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02310596 0,05918007 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02310596 0,05911425 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02310596 0,05904856 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02310596 0,05898303 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02310596 0,05891764 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02310596 0,05885239 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02310596 0,05878729 ! sterol catabolic process GO:0016127 9 8 0,000 0,02310596 0,05872233 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02310596 0,05865751 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02310596 0,05859284 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02310596 0,05852831 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02310596 0,05846392 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02310596 0,05839968 ! prophase GO:0051324 11 8 0,000 0,02310596 0,05833557 ! S phase GO:0051320 8 8 0,000 0,02310596 0,05827161 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02310596 0,05820778 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02310596 0,0581441 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02310596 0,05808055 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02310596 0,05801715 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02310596 0,05795388 ! hormone catabolic process GO:0042447 13 8 0,000 0,02310596 0,05789075 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02310596 0,05782776 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02310596 0,0577649 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02310596 0,05770218 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02310596 0,0576396 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02310596 0,05757715 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02310596 0,05751483 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02310596 0,05745266 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02310596 0,05739061 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02310596 0,0573287 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02310596 0,05726693 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02310596 0,05720528 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02310596 0,05714377 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02310596 0,05708239 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02310596 0,05702114 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02310596 0,05696003 ! mRNA transport GO:0051028 121 81 1,000 0,02334737 0,05749352 ! vitamin metabolic process GO:0006766 103 81 1,000 0,02334737 0,05743203 ! regulation of defense response GO:0031347 117 84 1,000 0,02498167 0,06138659 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,02498167 0,06132107 ! sterol metabolic process GO:0016125 120 84 1,000 0,02498167 0,0612557 ! Golgi vesicle transport GO:0048193 138 85 1,000 0,0255366 0,06254971 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,0255366 0,06248317 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,0255366 0,06241677 ! regulation of membrane potential GO:0042391 128 85 1,000 0,0255366 0,06235051 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02595714 0,06331011 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02595714 0,06324304 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02595714 0,06317612 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02595714 0,06310934 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02595714 0,06304269 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02595714 0,06297619 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02595714 0,06290983 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02595714 0,06284361 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02595714 0,06277753 ! GTP metabolic process GO:0046039 9 9 0,000 0,02595714 0,06271159 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02595714 0,06264578 ! social behavior GO:0035176 14 9 0,000 0,02595714 0,06258012 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02595714 0,06251459 ! artery development GO:0060840 19 9 0,000 0,02595714 0,0624492 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02595714 0,06238394 ! response to pain GO:0048265 16 9 0,000 0,02595714 0,06231882 ! protein complex disassembly GO:0043241 17 9 0,000 0,02595714 0,06225384 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02595714 0,06218899 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02595714 0,06212428 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02595714 0,0620597 ! lung alveolus development GO:0048286 17 9 0,000 0,02595714 0,06199526 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02595714 0,06193095 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02595714 0,06186677 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02595714 0,06180272 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02595714 0,06173881 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02595714 0,06167503 ! T cell selection GO:0045058 18 9 0,000 0,02595714 0,06161138 ! endoderm development GO:0007492 12 9 0,000 0,02595714 0,06154787 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02595714 0,06148448 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02595714 0,06142123 ! arginine catabolic process GO:0006527 10 9 0,000 0,02595714 0,0613581 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02595714 0,0612951 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02595714 0,06123224 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02595714 0,0611695 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02595714 0,06110689 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02595714 0,06104441 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02595714 0,06098205 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02595714 0,06091983 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02595714 0,06085773 ! mannose metabolic process GO:0006013 9 9 0,000 0,02595714 0,06079575 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02595714 0,06073391 ! receptor clustering GO:0043113 15 9 0,000 0,02595714 0,06067219 ! epithelial cell development GO:0002064 10 9 0,000 0,02595714 0,06061059 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02595714 0,06054912 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02595714 0,06048777 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02595714 0,06042655 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02595714 0,06036545 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02595714 0,06030448 ! motor axon guidance GO:0008045 14 9 0,000 0,02595714 0,06024362 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02595714 0,06018289 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02595714 0,06012229 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02595714 0,0600618 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02595714 0,06000144 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02595714 0,0599412 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02595714 0,05988107 ! DNA ligation GO:0006266 14 9 0,000 0,02595714 0,05982107 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02595714 0,05976119 ! response to amine stimulus GO:0014075 13 9 0,000 0,02595714 0,05970143 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02595714 0,05964179 ! erythrocyte development GO:0048821 11 9 0,000 0,02595714 0,05958227 ! renal water homeostasis GO:0003091 14 9 0,000 0,02595714 0,05952286 ! postreplication repair GO:0006301 11 9 0,000 0,02595714 0,05946358 ! mRNA cleavage GO:0006379 13 9 0,000 0,02595714 0,05940441 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02595714 0,05934536 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02595714 0,05928643 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02595714 0,05922761 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02595714 0,05916891 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02595714 0,05911033 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02595714 0,05905186 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02595714 0,05899351 ! acid secretion GO:0046717 14 9 0,000 0,02595714 0,05893527 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02595714 0,05887715 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02595714 0,05881914 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02595714 0,05876125 ! purine base metabolic process GO:0006144 18 9 0,000 0,02595714 0,05870347 ! oocyte differentiation GO:0009994 12 9 0,000 0,02595714 0,05864581 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02595714 0,05858825 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02595714 0,05853081 ! spleen development GO:0048536 15 9 0,000 0,02595714 0,05847349 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02595714 0,05841627 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02595714 0,05835917 ! detection of calcium ion GO:0005513 13 9 0,000 0,02595714 0,05830218 ! blastocyst formation GO:0001825 12 9 0,000 0,02595714 0,0582453 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02595714 0,05818853 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02595714 0,05813187 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02595714 0,05807532 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02595714 0,05801888 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02595714 0,05796255 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02595714 0,05790633 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02595714 0,05785022 ! prepulse inhibition GO:0060134 14 9 0,000 0,02595714 0,05779422 ! embryonic placenta development GO:0001892 12 9 0,000 0,02595714 0,05773833 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02595714 0,05768254 ! insulin secretion GO:0030073 17 9 0,000 0,02595714 0,05762686 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02595714 0,05757129 ! response to nicotine GO:0035094 16 9 0,000 0,02595714 0,05751583 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02595714 0,05746047 ! nucleus localization GO:0051647 15 9 0,000 0,02595714 0,05740522 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02595714 0,05735008 ! localization within membrane GO:0051668 15 9 0,000 0,02595714 0,05729504 ! establishment of RNA localization GO:0051236 128 88 1,000 0,0272314 0,06005007 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! leukocyte differentiation GO:0002521 143 90 1,000 0,02838595 0,06253611 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,02838595 0,06247626 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02880017 0,06332733 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02880017 0,06326685 ! neuron fate specification GO:0048665 11 10 0,000 0,02880017 0,06320648 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02880017 0,06314622 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02880017 0,06308609 ! thyroid gland development GO:0030878 19 10 0,000 0,02880017 0,06302606 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02880017 0,06296615 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02880017 0,06290635 ! synapsis GO:0007129 13 10 0,000 0,02880017 0,06284667 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02880017 0,0627871 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02880017 0,06272764 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02880017 0,0626683 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02880017 0,06260906 ! sulfate transport GO:0008272 12 10 0,000 0,02880017 0,06254994 ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02880017 0,06249093 ! androgen metabolic process GO:0008209 13 10 0,000 0,02880017 0,06243204 ! phospholipid efflux GO:0033700 16 10 0,000 0,02880017 0,06237325 ! hippocampus development GO:0021766 19 10 0,000 0,02880017 0,06231457 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,02880017 0,06225601 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02880017 0,06219755 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02880017 0,0621392 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02880017 0,06208097 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02880017 0,06202284 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02880017 0,06196482 ! pathogenesis GO:0009405 13 10 0,000 0,02880017 0,06190691 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02880017 0,0618491 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02880017 0,06179141 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02880017 0,06173382 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02880017 0,06167634 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02880017 0,06161897 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02880017 0,0615617 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02880017 0,06150454 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02880017 0,06144749 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02880017 0,06139054 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02880017 0,06133369 ! B cell proliferation GO:0042100 14 10 0,000 0,02880017 0,06127696 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02880017 0,06122032 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02880017 0,0611638 ! forebrain cell migration GO:0021885 17 10 0,000 0,02880017 0,06110737 ! lipid digestion GO:0044241 15 10 0,000 0,02880017 0,06105105 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02880017 0,06099483 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02880017 0,06093872 ! UV protection GO:0009650 14 10 0,000 0,02880017 0,06088271 ! entry into host cell GO:0030260 20 10 0,000 0,02880017 0,0608268 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02880017 0,060771 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02880017 0,0607153 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02880017 0,0606597 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02880017 0,0606042 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02880017 0,0605488 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02880017 0,06049351 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02880017 0,06043831 ! regulation of organ growth GO:0046620 11 10 0,000 0,02880017 0,06038322 ! response to dsRNA GO:0043331 18 10 0,000 0,02880017 0,06032822 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02880017 0,06027333 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02880017 0,06021854 ! embryonic axis specification GO:0000578 12 10 0,000 0,02880017 0,06016384 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02880017 0,06010925 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02880017 0,06005475 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02880017 0,06000035 ! cranial nerve development GO:0021545 12 10 0,000 0,02880017 0,05994605 ! fucose catabolic process GO:0019317 16 10 0,000 0,02880017 0,05989185 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02880017 0,05983775 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02880017 0,05978375 ! protein sumoylation GO:0016925 12 10 0,000 0,02880017 0,05972984 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02880017 0,05967603 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02880017 0,05962231 ! zymogen activation GO:0031638 14 10 0,000 0,02880017 0,0595687 ! salivary gland development GO:0007431 22 10 0,000 0,02880017 0,05951518 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02880017 0,05946175 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02880017 0,05940842 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02880017 0,05935519 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02880017 0,05930205 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02880017 0,05924901 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02880017 0,05919606 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02880017 0,05914321 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02880017 0,05909045 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02880017 0,05903778 ! detection of bacterium GO:0016045 10 10 0,000 0,02880017 0,05898521 ! embryonic gut development GO:0048566 11 10 0,000 0,02880017 0,05893273 ! activation of innate immune response GO:0002218 10 10 0,000 0,02880017 0,05888035 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02880017 0,05882806 ! developmental induction GO:0031128 13 10 0,000 0,02880017 0,05877586 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02880017 0,05872375 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02880017 0,05867174 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02880017 0,05861981 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02880017 0,05856798 ! RNA localization GO:0006403 135 91 1,000 0,02897054 0,05886241 ! cell fate commitment GO:0045165 141 92 1,000 0,02955996 0,06000697 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,03015417 0,06115925 ! regulation of binding GO:0051098 151 95 1,000 0,03135687 0,06354255 ! rRNA transcription GO:0009303 17 11 0,000 0,03163506 0,06404986 ! respiratory burst GO:0045730 14 11 0,000 0,03163506 0,06399352 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03163506 0,06393729 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03163506 0,06388116 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03163506 0,06382512 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,03163506 0,06376918 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03163506 0,06371334 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03163506 0,0636576 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03163506 0,06360195 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03163506 0,06354641 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03163506 0,06349096 ! mating GO:0007618 14 11 0,000 0,03163506 0,0634356 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03163506 0,06338035 ! T cell proliferation GO:0042098 20 11 0,000 0,03163506 0,06332518 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03163506 0,06327012 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03163506 0,06321515 ! bone resorption GO:0045453 16 11 0,000 0,03163506 0,06316027 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03163506 0,0631055 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03163506 0,06305081 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03163506 0,06299622 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03163506 0,06294173 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03163506 0,06288733 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03163506 0,06283302 ! syncytium formation GO:0006949 15 11 0,000 0,03163506 0,06277881 ! plasma membrane organization GO:0007009 18 11 0,000 0,03163506 0,06272469 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03163506 0,06267066 ! focal adhesion formation GO:0048041 24 11 0,000 0,03163506 0,06261673 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03163506 0,06256289 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03163506 0,06250914 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03163506 0,06245548 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03163506 0,06240192 ! adult heart development GO:0007512 11 11 0,000 0,03163506 0,06234845 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03163506 0,06229507 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03163506 0,06224178 ! temperature homeostasis GO:0001659 16 11 0,000 0,03163506 0,06218858 ! L-glutamate transport GO:0015813 16 11 0,000 0,03163506 0,06213547 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03163506 0,06208245 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03163506 0,06202953 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03163506 0,06197669 ! stem cell development GO:0048864 29 11 0,000 0,03163506 0,06192395 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03163506 0,06187129 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03163506 0,06181872 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03163506 0,06176624 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03163506 0,06171386 ! vasoconstriction GO:0042310 15 11 0,000 0,03163506 0,06166156 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03163506 0,06160934 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03163506 0,06155722 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03163506 0,06150519 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03163506 0,06145324 ! ribosome assembly GO:0042255 13 11 0,000 0,03163506 0,06140138 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03163506 0,06134961 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03163506 0,06129792 ! chromatin silencing GO:0006342 19 11 0,000 0,03163506 0,06124633 ! nucleosome positioning GO:0016584 13 11 0,000 0,03163506 0,06119482 ! T cell homeostasis GO:0043029 20 11 0,000 0,03163506 0,06114339 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03163506 0,06109205 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03163506 0,0610408 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03163506 0,06098964 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03163506 0,06093856 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03163506 0,06088756 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03163506 0,06083665 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03163506 0,06078583 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03163506 0,06073509 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03163506 0,06068443 ! male genitalia development GO:0030539 13 11 0,000 0,03163506 0,06063386 ! cholesterol efflux GO:0033344 19 11 0,000 0,03163506 0,06058338 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03163506 0,06053298 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03163506 0,06048266 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03163506 0,06043242 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03163506 0,06038227 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03163506 0,0603322 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03163506 0,06028222 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03163506 0,06023231 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03163506 0,06018249 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03163506 0,06013276 ! lysogeny GO:0030069 18 11 0,000 0,03163506 0,0600831 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03163506 0,06003353 ! acrosome reaction GO:0007340 13 11 0,000 0,03163506 0,05998404 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03163506 0,05993463 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,03196529 0,06051042 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,03196529 0,06046065 ! response to light stimulus GO:0009416 153 96 1,000 0,03196529 0,06041097 ! extracellular structure organization GO:0043062 156 99 1,000 0,03381844 0,06386077 ! protein import GO:0017038 156 99 1,000 0,03381844 0,06380839 ! protein localization in organelle GO:0033365 161 100 1,000 0,03444536 0,06493798 ! lactation GO:0007595 20 12 0,000 0,03446184 0,06491582 ! reproductive cellular process GO:0048610 14 12 0,000 0,03446184 0,0648627 ! tRNA modification GO:0006400 14 12 0,000 0,03446184 0,06480967 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03446184 0,06475672 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03446184 0,06470385 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03446184 0,06465108 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03446184 0,06459839 ! non-recombinational repair GO:0000726 19 12 0,000 0,03446184 0,06454578 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03446184 0,06449326 ! peroxisomal transport GO:0043574 21 12 0,000 0,03446184 0,06444083 ! cartilage condensation GO:0001502 18 12 0,000 0,03446184 0,06438848 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03446184 0,06433622 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03446184 0,06428404 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03446184 0,06423195 ! heart looping GO:0001947 15 12 0,000 0,03446184 0,06417994 ! palate development GO:0060021 15 12 0,000 0,03446184 0,06412801 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03446184 0,06407617 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03446184 0,06402441 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03446184 0,06397274 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03446184 0,06392115 ! arginine metabolic process GO:0006525 13 12 0,000 0,03446184 0,06386964 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03446184 0,06381821 ! methionine metabolic process GO:0006555 13 12 0,000 0,03446184 0,06376687 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03446184 0,06371561 ! Golgi organization GO:0007030 18 12 0,000 0,03446184 0,06366444 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03446184 0,06361334 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03446184 0,06356233 ! monoamine transport GO:0015844 13 12 0,000 0,03446184 0,0635114 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03446184 0,06346055 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03446184 0,06340978 ! L-amino acid transport GO:0015807 20 12 0,000 0,03446184 0,06335909 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03446184 0,06330848 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03446184 0,06325796 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03446184 0,06320751 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03446184 0,06315715 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03446184 0,06310686 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03446184 0,06305666 ! cerebellum development GO:0021549 13 12 0,000 0,03446184 0,06300654 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03446184 0,06295649 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03446184 0,06290653 ! histone methylation GO:0016571 15 12 0,000 0,03446184 0,06285664 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03446184 0,06280683 ! gland morphogenesis GO:0022612 23 12 0,000 0,03446184 0,0627571 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03446184 0,06270745 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03446184 0,06265788 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03446184 0,06260839 ! intestinal absorption GO:0050892 19 12 0,000 0,03446184 0,06255898 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03446184 0,06250964 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03446184 0,06246038 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03446184 0,0624112 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03446184 0,06236209 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03446184 0,06231307 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03446184 0,06226412 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03446184 0,06221524 ! microspike assembly GO:0030035 23 12 0,000 0,03446184 0,06216645 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03446184 0,06211773 ! response to cold GO:0009409 14 12 0,000 0,03446184 0,06206909 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,03728052 0,06709327 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03728052 0,06704081 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03728052 0,06698844 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03728052 0,06693614 ! water transport GO:0006833 17 13 0,000 0,03728052 0,06688393 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03728052 0,0668318 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03728052 0,06677975 ! lipid localization GO:0010876 24 13 0,000 0,03728052 0,06672778 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03728052 0,06667589 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03728052 0,06662409 ! organelle fusion GO:0048284 28 13 0,000 0,03728052 0,06657236 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03728052 0,06652071 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03728052 0,06646915 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03728052 0,06641766 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03728052 0,06636625 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03728052 0,06631493 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03728052 0,06626368 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03728052 0,06621251 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03728052 0,06616142 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03728052 0,06611041 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,03728052 0,06605948 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,03728052 0,06600862 ! NAD metabolic process GO:0019674 21 13 0,000 0,03728052 0,06595785 ! exocrine system development GO:0035272 27 13 0,000 0,03728052 0,06590715 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03728052 0,06585653 ! bone mineralization GO:0030282 15 13 0,000 0,03728052 0,06580599 ! regulation of exocytosis GO:0017157 17 13 0,000 0,03728052 0,06575552 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03728052 0,06570513 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03728052 0,06565482 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,03728052 0,06560459 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03728052 0,06555443 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,03728052 0,06550435 ! genitalia development GO:0048806 15 13 0,000 0,03728052 0,06545435 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,03728052 0,06540442 ! cellular pigmentation GO:0033059 24 13 0,000 0,03728052 0,06535457 ! tissue regeneration GO:0042246 21 13 0,000 0,03728052 0,0653048 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03728052 0,0652551 ! cofactor transport GO:0051181 19 13 0,000 0,03728052 0,06520548 ! NADP metabolic process GO:0006739 18 13 0,000 0,03728052 0,06515593 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03728052 0,06510645 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03728052 0,06505706 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03728052 0,06500773 ! gas transport GO:0015669 18 13 0,000 0,03728052 0,06495848 ! regulation of RNA stability GO:0043487 28 13 0,000 0,03728052 0,06490931 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03728052 0,06486021 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03728052 0,06481119 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03728052 0,06476224 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03728052 0,06471336 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03728052 0,06466456 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03728052 0,06461583 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,03728052 0,06456717 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04009114 0,06938271 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04009114 0,06933054 ! superoxide anion generation GO:0042554 18 14 0,000 0,04009114 0,06927845 ! regulation of S phase GO:0033261 18 14 0,000 0,04009114 0,06922644 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04009114 0,06917451 ! myotube differentiation GO:0014902 21 14 0,000 0,04009114 0,06912266 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,04009114 0,06907088 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04009114 0,06901918 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04009114 0,06896756 ! inositol metabolic process GO:0006020 20 14 0,000 0,04009114 0,06891601 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04009114 0,06886454 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04009114 0,06881315 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04009114 0,06876184 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04009114 0,0687106 ! response to cAMP GO:0051591 19 14 0,000 0,04009114 0,06865944 ! limbic system development GO:0021761 25 14 0,000 0,04009114 0,06860835 ! startle response GO:0001964 21 14 0,000 0,04009114 0,06855734 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04009114 0,06850641 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04009114 0,06845555 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04009114 0,06840476 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04009114 0,06835406 ! glycine metabolic process GO:0006544 22 14 0,000 0,04009114 0,06830342 ! pituitary gland development GO:0021983 23 14 0,000 0,04009114 0,06825287 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04009114 0,06820238 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04009114 0,06815198 ! regulation of heart rate GO:0002027 23 14 0,000 0,04009114 0,06810164 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04009114 0,06805138 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04009114 0,0680012 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04009114 0,06795109 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04009114 0,06790105 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04009114 0,06785108 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04009114 0,06780119 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04009114 0,06775138 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04009114 0,06770163 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04009114 0,06765196 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04009114 0,06760236 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04009114 0,06755284 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04009114 0,06750338 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04009114 0,067454 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04009114 0,06740469 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04009114 0,06735546 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04009114 0,06730629 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04009114 0,0672572 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04009114 0,06720818 ! muscle maintenance GO:0046716 19 14 0,000 0,04009114 0,06715923 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04009114 0,06711035 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04009114 0,06706154 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04009114 0,06701281 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04009114 0,06696414 ! cell killing GO:0001906 20 14 0,000 0,04009114 0,06691555 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04009114 0,06686702 ! cilium assembly GO:0042384 20 14 0,000 0,04009114 0,06681857 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04009114 0,06677018 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04289371 0,07138606 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04289371 0,07133445 ! metencephalon development GO:0022037 19 15 0,000 0,04289371 0,07128291 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04289371 0,07123144 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04289371 0,07118004 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04289371 0,07112872 ! skin development GO:0043588 25 15 0,000 0,04289371 0,07107748 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04289371 0,07102631 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04289371 0,07097521 ! lipid phosphorylation GO:0046834 23 15 0,000 0,04289371 0,07092418 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,04289371 0,07087323 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04289371 0,07082236 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,04289371 0,07077155 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04289371 0,07072082 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04289371 0,07067016 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04289371 0,07061957 ! adult walking behavior GO:0007628 25 15 0,000 0,04289371 0,07056906 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04289371 0,07051861 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04289371 0,07046824 ! myoblast differentiation GO:0045445 27 15 0,000 0,04289371 0,07041795 ! centrosome cycle GO:0007098 16 15 0,000 0,04289371 0,07036772 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04289371 0,07031756 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,04289371 0,07026748 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04289371 0,07021747 ! cerebral cortex development GO:0021987 29 15 0,000 0,04289371 0,07016753 ! response to osmotic stress GO:0006970 22 15 0,000 0,04289371 0,07011766 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04289371 0,07006786 ! DNA integration GO:0015074 22 15 0,000 0,04289371 0,07001813 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,04289371 0,06996847 ! peptide secretion GO:0002790 27 15 0,000 0,04289371 0,06991888 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,04289371 0,06986936 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04289371 0,06981992 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04289371 0,06977054 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,04289371 0,06972123 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04289371 0,06967199 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04289371 0,06962282 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,04289371 0,06957372 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04289371 0,06952469 ! biomineral formation GO:0031214 18 15 0,000 0,04289371 0,06947573 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04289371 0,06942684 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04289371 0,06937802 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04289371 0,06932926 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04289371 0,06928058 ! organic cation transport GO:0015695 19 15 0,000 0,04289371 0,06923196 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04289371 0,06918341 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,04289371 0,06913493 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,04289371 0,06908651 ! peptide hormone processing GO:0016486 19 15 0,000 0,04289371 0,06903817 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,04289371 0,06898989 ! protein secretion GO:0009306 27 16 0,000 0,04568826 0,07343327 ! hormone secretion GO:0046879 25 16 0,000 0,04568826 0,07338199 ! bone remodeling GO:0046849 24 16 0,000 0,04568826 0,07333078 ! endothelial cell migration GO:0043542 22 16 0,000 0,04568826 0,07327964 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04568826 0,07322858 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04568826 0,07317758 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04568826 0,07312666 ! glial cell development GO:0021782 24 16 0,000 0,04568826 0,07307581 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04568826 0,07302502 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04568826 0,07297431 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04568826 0,07292367 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04568826 0,0728731 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04568826 0,0728226 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04568826 0,07277217 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04568826 0,07272181 ! fructose metabolic process GO:0006000 20 16 0,000 0,04568826 0,07267151 ! regulation of protein binding GO:0043393 27 16 0,000 0,04568826 0,07262129 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04568826 0,07257114 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04568826 0,07252105 ! protein export from nucleus GO:0006611 24 16 0,000 0,04568826 0,07247104 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04568826 0,07242109 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04568826 0,07237122 ! DNA replication initiation GO:0006270 25 16 0,000 0,04568826 0,07232141 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04568826 0,07227167 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04568826 0,072222 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04568826 0,0721724 ! diencephalon development GO:0021536 25 16 0,000 0,04568826 0,07212286 ! oogenesis GO:0048477 23 16 0,000 0,04568826 0,07207339 ! neural crest cell migration GO:0001755 24 16 0,000 0,04568826 0,07202399 ! G1 phase GO:0051318 27 16 0,000 0,04568826 0,07197466 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04568826 0,0719254 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04568826 0,0718762 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04568826 0,07182707 ! steroid catabolic process GO:0006706 22 16 0,000 0,04568826 0,07177801 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04568826 0,07172902 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04568826 0,07168009 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04568826 0,07163123 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04568826 0,07158243 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04568826 0,0715337 ! nerve development GO:0021675 18 16 0,000 0,04568826 0,07148504 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04568826 0,07143644 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04568826 0,07138791 ! negative regulation of translation GO:0017148 22 16 0,000 0,04568826 0,07133945 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04847482 0,07563913 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04847482 0,07558785 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04847482 0,07553664 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04847482 0,07548549 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04847482 0,07543442 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04847482 0,07538342 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04847482 0,07533248 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04847482 0,07528162 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04847482 0,07523082 ! signal complex assembly GO:0007172 29 17 0,000 0,04847482 0,07518009 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04847482 0,07512943 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,04847482 0,07507884 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04847482 0,07502831 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04847482 0,07497786 ! memory GO:0007613 25 17 0,000 0,04847482 0,07492747 ! keratinization GO:0031424 17 17 0,000 0,04847482 0,07487715 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04847482 0,0748269 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04847482 0,07477671 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04847482 0,07472659 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04847482 0,07467654 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,04847482 0,07462656 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04847482 0,07457664 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,04847482 0,07452679 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,04847482 0,074477 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,04847482 0,07442729 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04847482 0,07437764 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,04847482 0,07432805 ! heme metabolic process GO:0042168 27 17 0,000 0,04847482 0,07427853 ! actin filament bundle formation GO:0051017 26 17 0,000 0,04847482 0,07422908 ! neuromuscular junction development GO:0007528 23 17 0,000 0,04847482 0,07417969 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,04847482 0,07413037 ! body fluid secretion GO:0007589 27 17 0,000 0,04847482 0,07408111 ! stem cell differentiation GO:0048863 36 17 0,000 0,04847482 0,07403192 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,04847482 0,0739828 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04847482 0,07393374 ! sensory perception of pain GO:0019233 23 17 0,000 0,04847482 0,07388474 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04847482 0,07383581 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04847482 0,07378695 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,04847482 0,07373815 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,04847482 0,07368941 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04847482 0,07364074 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04847482 0,07359213 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04847482 0,07354359 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04847482 0,07349511 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04847482 0,07344669 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04847482 0,07339834 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,04847482 0,07335005 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04847482 0,07330182 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04847482 0,07325366 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,05125339 0,0774017 ! positive regulation of translation GO:0045727 28 18 0,000 0,05125339 0,07735091 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05125339 0,07730019 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05125339 0,07724954 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05125339 0,07719895 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05125339 0,07714843 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05125339 0,07709797 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05125339 0,07704758 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05125339 0,07699725 ! axis specification GO:0009798 26 18 0,000 0,05125339 0,07694699 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05125339 0,0768968 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05125339 0,07684667 ! pancreas development GO:0031016 26 18 0,000 0,05125339 0,07679661 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05125339 0,07674661 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05125339 0,07669668 ! pigmentation during development GO:0048066 31 18 0,000 0,05125339 0,07664681 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05125339 0,07659701 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,05125339 0,07654727 ! fucose metabolic process GO:0006004 26 18 0,000 0,05125339 0,0764976 ! response to fungus GO:0009620 19 18 0,000 0,05125339 0,07644799 ! peptide cross-linking GO:0018149 31 18 0,000 0,05125339 0,07639844 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05125339 0,07634896 ! heart process GO:0003015 27 18 0,000 0,05125339 0,07629954 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05125339 0,07625019 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05125339 0,0762009 ! visual learning GO:0008542 35 18 0,000 0,05125339 0,07615168 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05125339 0,07610251 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,05125339 0,07605342 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05125339 0,07600438 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05125339 0,07595541 ! vitamin transport GO:0051180 24 18 0,000 0,05125339 0,0759065 ! hormone transport GO:0009914 27 18 0,000 0,05125339 0,07585765 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05125339 0,07580887 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05125339 0,07576015 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05125339 0,07571149 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05125339 0,0756629 ! cell-cell recognition GO:0009988 20 18 0,000 0,05125339 0,07561436 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05125339 0,07556589 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05125339 0,07551749 ! regulation of glucose import GO:0046324 21 18 0,000 0,05125339 0,07546914 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,05125339 0,07542085 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05125339 0,07537263 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,05125339 0,07532447 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,05402401 0,0793456 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,05402401 0,07929497 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,05402401 0,0792444 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05402401 0,07919389 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05402401 0,07914345 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05402401 0,07909307 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05402401 0,07904276 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05402401 0,07899251 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,05402401 0,07894232 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05402401 0,0788922 ! regeneration GO:0031099 32 19 0,000 0,05402401 0,07884214 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05402401 0,07879215 ! response to alkaloid GO:0043279 32 19 0,000 0,05402401 0,07874222 ! sensory perception of taste GO:0050909 23 19 0,000 0,05402401 0,07869235 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,05402401 0,07864254 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,05402401 0,0785928 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05402401 0,07854312 ! peroxisome organization GO:0007031 29 19 0,000 0,05402401 0,0784935 ! digestive system process GO:0022600 30 19 0,000 0,05402401 0,07844395 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,05402401 0,07839446 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05402401 0,07834503 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05402401 0,07829566 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05402401 0,07824636 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,05402401 0,07819712 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,05402401 0,07814793 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05402401 0,07809882 ! plasma membrane fusion GO:0045026 23 19 0,000 0,05402401 0,07804976 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,05402401 0,07800076 ! cytolysis GO:0019835 20 19 0,000 0,05402401 0,07795183 ! renal system process GO:0003014 35 19 0,000 0,05402401 0,07790296 ! vasodilation GO:0042311 33 19 0,000 0,05402401 0,07785415 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05402401 0,0778054 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05402401 0,07775671 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05402401 0,07770808 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05402401 0,07765951 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05402401 0,077611 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,05402401 0,07756256 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05402401 0,07751417 ! sarcomere organization GO:0045214 23 19 0,000 0,05402401 0,07746585 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05402401 0,07741758 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,05402401 0,07736938 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05402401 0,07732123 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05402401 0,07727314 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05402401 0,07722512 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,05402401 0,07717715 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05402401 0,07712925 ! protein stabilization GO:0050821 26 19 0,000 0,05402401 0,0770814 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,05678669 0,08097297 ! iron ion transport GO:0006826 37 20 0,000 0,05678669 0,0809228 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,05678669 0,08087269 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,05678669 0,08082264 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,05678669 0,08077266 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,05678669 0,08072274 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,05678669 0,08067288 ! spinal cord development GO:0021510 31 20 0,000 0,05678669 0,08062308 ! response to ethanol GO:0045471 37 20 0,000 0,05678669 0,08057335 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,05678669 0,08052367 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,05678669 0,08047406 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,05678669 0,0804245 ! chromosome condensation GO:0030261 31 20 0,000 0,05678669 0,08037501 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,05678669 0,08032558 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,05678669 0,08027621 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,05678669 0,0802269 ! pallium development GO:0021543 38 20 0,000 0,05678669 0,08017765 ! DNA modification GO:0006304 28 20 0,000 0,05678669 0,08012846 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,05678669 0,08007933 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,05678669 0,08003027 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,05678669 0,07998126 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,05678669 0,07993231 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,05678669 0,07988342 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,05678669 0,07983459 ! collagen catabolic process GO:0030574 25 20 0,000 0,05678669 0,07978582 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,05678669 0,07973711 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,05678669 0,07968846 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,05678669 0,07963987 ! alditol metabolic process GO:0019400 24 20 0,000 0,05678669 0,07959134 ! actin filament-based movement GO:0030048 34 20 0,000 0,05678669 0,07954287 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,05954147 0,08335081 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,05954147 0,08330011 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,05954147 0,08324947 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,05954147 0,08319889 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,05954147 0,08314838 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,05954147 0,08309792 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,05954147 0,08304753 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,05954147 0,0829972 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,05954147 0,08294693 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,05954147 0,08289672 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,05954147 0,08284657 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,05954147 0,08279648 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,05954147 0,08274645 ! vesicle docking GO:0048278 27 21 0,000 0,05954147 0,08269648 ! phototransduction GO:0007602 25 21 0,000 0,05954147 0,08264658 ! dendrite development GO:0016358 35 21 0,000 0,05954147 0,08259673 ! visual behavior GO:0007632 39 21 0,000 0,05954147 0,08254694 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,05954147 0,08249721 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,05954147 0,08244755 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,05954147 0,08239794 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,05954147 0,08234839 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,05954147 0,0822989 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,05954147 0,08224947 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,05954147 0,08220011 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,05954147 0,08215079 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,05954147 0,08210154 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,05954147 0,08205235 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,05954147 0,08200322 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,05954147 0,08195414 ! fatty acid transport GO:0015908 30 21 0,000 0,05954147 0,08190513 ! immunoglobulin production GO:0002377 33 21 0,000 0,05954147 0,08185617 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,05954147 0,08180727 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,05954147 0,08175843 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,05954147 0,08170965 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,05954147 0,08166093 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,05954147 0,08161226 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,05954147 0,08156365 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,05954147 0,0815151 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,05954147 0,08146661 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,05954147 0,08141818 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,05954147 0,0813698 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,05954147 0,08132148 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,05954147 0,08127322 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,05954147 0,08122501 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06228835 0,08492188 ! viral genome replication GO:0019079 29 22 0,000 0,06228835 0,08487157 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06228835 0,08482132 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,06228835 0,08477113 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06228835 0,084721 ! molting cycle process GO:0022404 40 22 0,000 0,06228835 0,08467093 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06228835 0,08462092 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,06228835 0,08457096 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06228835 0,08452107 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,06228835 0,08447123 ! vasculogenesis GO:0001570 33 22 0,000 0,06228835 0,08442146 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,06228835 0,08437174 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,06228835 0,08432208 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06228835 0,08427248 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06228835 0,08422294 ! lysosome organization GO:0007040 37 22 0,000 0,06228835 0,08417345 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06228835 0,08412402 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,06228835 0,08407466 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06228835 0,08402535 ! regulation of behavior GO:0050795 38 22 0,000 0,06228835 0,08397609 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06228835 0,0839269 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06228835 0,08387776 ! membrane depolarization GO:0051899 35 22 0,000 0,06228835 0,08382868 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06228835 0,08377966 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06228835 0,08373069 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06228835 0,08368178 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06228835 0,08363293 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06228835 0,08358414 ! blastocyst development GO:0001824 37 22 0,000 0,06228835 0,0835354 ! neural tube closure GO:0001843 33 22 0,000 0,06228835 0,08348672 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06228835 0,0834381 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06502737 0,08705644 ! neuron fate commitment GO:0048663 32 23 0,000 0,06502737 0,08700579 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06502737 0,08695521 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,06502737 0,08690468 ! myelination GO:0042552 35 23 0,000 0,06502737 0,08685422 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06502737 0,08680381 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06502737 0,08675346 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,06502737 0,08670317 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06502737 0,08665293 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06502737 0,08660276 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06502737 0,08655264 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06502737 0,08650258 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06502737 0,08645258 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06502737 0,08640263 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06502737 0,08635275 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06502737 0,08630292 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,06502737 0,08625315 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06502737 0,08620344 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06502737 0,08615378 ! cell fate determination GO:0001709 45 23 0,000 0,06502737 0,08610418 ! pentose metabolic process GO:0019321 31 23 0,000 0,06502737 0,08605464 ! spermatid development GO:0007286 33 23 0,000 0,06502737 0,08600515 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06502737 0,08595572 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06502737 0,08590635 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06502737 0,08585704 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06502737 0,08580778 ! telomere organization GO:0032200 32 23 0,000 0,06502737 0,08575858 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,06502737 0,08570943 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06502737 0,08566034 ! regulation of amine transport GO:0051952 38 23 0,000 0,06502737 0,08561131 ! liver development GO:0001889 40 23 0,000 0,06502737 0,08556233 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,06775855 0,08910501 ! initiation of viral infection GO:0019059 42 24 0,000 0,06775855 0,08905409 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,06775855 0,08900324 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,06775855 0,08895243 ! superoxide metabolic process GO:0006801 32 24 0,000 0,06775855 0,08890169 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,06775855 0,08885101 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,06775855 0,08880038 ! fat cell differentiation GO:0045444 37 24 0,000 0,06775855 0,08874981 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,06775855 0,0886993 ! sperm motility GO:0030317 27 24 0,000 0,06775855 0,08864884 ! vacuole organization GO:0007033 39 24 0,000 0,06775855 0,08859845 ! receptor metabolic process GO:0043112 37 24 0,000 0,06775855 0,08854811 ! neural crest cell development GO:0014032 39 24 0,000 0,06775855 0,08849782 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,06775855 0,0884476 ! primary neural tube formation GO:0014020 35 24 0,000 0,06775855 0,08839743 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,06775855 0,08834732 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,06775855 0,08829726 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,06775855 0,08824726 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,06775855 0,08819732 ! glutathione metabolic process GO:0006749 29 24 0,000 0,06775855 0,08814744 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,06775855 0,08809761 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,06775855 0,08804783 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,06775855 0,08799812 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,0704819 0,09148328 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,0704819 0,09143169 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,0704819 0,09138015 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,0704819 0,09132866 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,0704819 0,09127724 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,0704819 0,09122587 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,0704819 0,09117457 ! peptide transport GO:0015833 43 25 0,000 0,0704819 0,09112332 ! iron ion homeostasis GO:0055072 39 25 0,000 0,0704819 0,09107212 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,0704819 0,09102099 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,0704819 0,09096991 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,0704819 0,09091889 ! phospholipid transport GO:0015914 35 25 0,000 0,0704819 0,09086793 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,0704819 0,09081702 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,0704819 0,09076617 ! detection of light stimulus GO:0009583 30 25 0,000 0,0704819 0,09071538 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,0704819 0,09066464 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,0704819 0,09061396 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,0704819 0,09056334 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07319746 0,09400009 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,07319746 0,09394763 ! translational initiation GO:0006413 43 26 0,000 0,07319746 0,09389523 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,07319746 0,09384289 ! circadian rhythm GO:0007623 42 26 0,000 0,07319746 0,09379061 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07319746 0,09373839 ! post-embryonic development GO:0009791 42 26 0,000 0,07319746 0,09368623 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07319746 0,09363412 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07319746 0,09358208 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07319746 0,09353009 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,07319746 0,09347815 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07319746 0,09342628 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,07319746 0,09337446 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07319746 0,0933227 ! regulation of coagulation GO:0050818 39 26 0,000 0,07319746 0,093271 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,07590523 0,09666779 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,07590523 0,0966143 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,07590523 0,09656086 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,07590523 0,09650748 ! membrane docking GO:0022406 39 27 0,000 0,07590523 0,09645416 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,07590523 0,0964009 ! catechol metabolic process GO:0009712 43 27 0,000 0,07590523 0,0963477 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,07590523 0,09629456 ! acute-phase response GO:0006953 42 27 0,000 0,07590523 0,09624148 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,07590523 0,09618845 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,07590523 0,09613548 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,07590523 0,09608257 ! natural killer cell activation GO:0030101 35 27 0,000 0,07590523 0,09602972 ! lipid oxidation GO:0034440 38 27 0,000 0,07590523 0,09597693 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,07590523 0,0959242 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,07590523 0,09587152 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,07590523 0,0958189 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,07590523 0,09576634 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,07590523 0,09571384 ! gene silencing GO:0016458 41 27 0,000 0,07590523 0,09566139 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,07860525 0,0990099 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,07860525 0,09895571 ! phenol metabolic process GO:0018958 44 28 0,000 0,07860525 0,09890158 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,07860525 0,0988475 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,07860525 0,09879349 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,07860525 0,09873953 ! cell junction assembly GO:0034329 56 28 0,000 0,07860525 0,09868563 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,07860525 0,0986318 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,07860525 0,09857802 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,07860525 0,09852429 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,07860525 0,09847063 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,07860525 0,09841703 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,07860525 0,09836348 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,07860525 0,09831 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,07860525 0,09825657 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,07860525 0,09820319 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,07860525 0,09814988 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,07860525 0,09809663 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,07860525 0,09804343 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,07860525 0,09799029 ! ensheathment of neurons GO:0007272 43 28 0,000 0,07860525 0,09793721 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,07860525 0,09788418 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,07860525 0,09783121 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,07860525 0,0977783 ! neural tube formation GO:0001841 41 28 0,000 0,07860525 0,09772545 ! placenta development GO:0001890 37 28 0,000 0,07860525 0,09767265 ! regulation of B cell activation GO:0050864 42 28 0,000 0,07860525 0,09761991 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,08129754 0,10090898 ! regulation of innate immune response GO:0045088 38 29 0,000 0,08129754 0,10085455 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,08129754 0,10080018 ! mismatch repair GO:0006298 34 29 0,000 0,08129754 0,10074587 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,08129754 0,10069162 ! telencephalon development GO:0021537 52 29 0,000 0,08129754 0,10063742 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,08129754 0,10058329 ! eye morphogenesis GO:0048592 51 29 0,000 0,08129754 0,10052921 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,08129754 0,10047519 ! tissue homeostasis GO:0001894 42 29 0,000 0,08129754 0,10042123 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,08398211 0,10368162 ! collagen metabolic process GO:0032963 40 30 0,000 0,08398211 0,10362599 ! organic anion transport GO:0015711 51 30 0,000 0,08398211 0,10357043 ! cholesterol transport GO:0030301 46 30 0,000 0,08398211 0,10351492 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,08398211 0,10345948 ! spliceosome assembly GO:0000245 49 30 0,000 0,08398211 0,1034041 ! spindle organization GO:0007051 37 30 0,000 0,08398211 0,10334877 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,08398211 0,1032935 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,08398211 0,10323829 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,08398211 0,10318315 ! ceramide metabolic process GO:0006672 43 30 0,000 0,08398211 0,10312806 ! hindbrain development GO:0030902 45 30 0,000 0,08398211 0,10307303 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,08398211 0,10301805 ! adult locomotory behavior GO:0008344 47 30 0,000 0,08398211 0,10296314 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,08398211 0,10290828 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,08398211 0,10285349 ! response to heat GO:0009408 41 30 0,000 0,08398211 0,10279875 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,08398211 0,10274407 ! negative regulation of secretion GO:0051048 49 31 0,000 0,08665899 0,10596261 ! mammary gland development GO:0030879 57 31 0,000 0,08665899 0,10590631 ! glial cell differentiation GO:0010001 55 31 0,000 0,08665899 0,10585007 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,08665899 0,10579388 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,08665899 0,10573776 ! odontogenesis GO:0042476 50 31 0,000 0,08665899 0,10568169 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,08665899 0,10562569 ! metanephros development GO:0001656 58 31 0,000 0,08665899 0,10556974 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,08665899 0,10551386 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,08665899 0,10545803 ! cell fate specification GO:0001708 37 31 0,000 0,08665899 0,10540226 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,08665899 0,10534655 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,08665899 0,1052909 ! RNA modification GO:0009451 40 31 0,000 0,08665899 0,10523531 ! regulation of muscle development GO:0048634 48 32 0,000 0,0893282 0,10841945 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,0893282 0,10836227 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,0893282 0,10830514 ! meiosis I GO:0007127 52 32 0,000 0,0893282 0,10824808 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,0893282 0,10819108 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,0893282 0,10813414 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 0,000 0,0893282 0,10807725 ! regulation of protein stability GO:0031647 48 32 0,000 0,0893282 0,10802043 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,0893282 0,10796367 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,0893282 0,10790696 ! cytokine production GO:0001816 44 32 0,000 0,0893282 0,10785032 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,0893282 0,10779373 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,09198976 0,11094727 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,09198976 0,11088913 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,09198976 0,11083104 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,09198976 0,11077301 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,09198976 0,11071505 ! sister chromatid segregation GO:0000819 46 33 0,000 0,09198976 0,11065714 ! ear morphogenesis GO:0042471 42 33 0,000 0,09198976 0,11059929 ! cell junction organization GO:0034330 63 33 0,000 0,09198976 0,11054151 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,09198976 0,11048379 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,09198976 0,11042612 ! nucleus organization GO:0006997 49 33 0,000 0,09198976 0,11036852 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,09198976 0,11031098 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,09198976 0,11025349 ! positive regulation of cell development GO:0010720 54 33 0,000 0,09198976 0,11019607 ! lipid homeostasis GO:0055088 55 33 0,000 0,09198976 0,1101387 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,09198976 0,1100814 ! regulation of proteolysis GO:0030162 50 33 0,000 0,09198976 0,11002416 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,09198976 0,10996697 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,09198976 0,10990984 ! cytokinesis GO:0000910 52 33 0,000 0,09198976 0,10985278 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,09198976 0,10979577 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,0946437 0,11290483 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,0946437 0,1128463 ! feeding behavior GO:0007631 45 34 0,000 0,0946437 0,11278783 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,0946437 0,11272942 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,0946437 0,11267107 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,0946437 0,11261278 ! female gamete generation GO:0007292 43 34 0,000 0,0946437 0,11255455 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,0946437 0,11249638 ! polyol metabolic process GO:0019751 44 34 0,000 0,0946437 0,11243828 ! aerobic respiration GO:0009060 47 34 0,000 0,0946437 0,11238023 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,0946437 0,11232224 ! embryonic organ development GO:0048568 45 34 0,000 0,0946437 0,11226431 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,09729003 0,11534385 ! Notch signaling pathway GO:0007219 56 35 0,000 0,09729003 0,11528442 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,09729003 0,11522506 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,09729003 0,11516576 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,09729003 0,11510651 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,09729003 0,11504733 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,09729003 0,11498821 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,09729003 0,11492915 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,09729003 0,11487016 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,09729003 0,11481122 ! glycogen metabolic process GO:0005977 48 35 0,000 0,09729003 0,11475234 ! pigment metabolic process GO:0042440 61 35 0,000 0,09729003 0,11469352 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,09729003 0,11463477 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,09729003 0,11457607 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,09992877 0,11762343 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,09992877 0,11756326 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,09992877 0,11750316 ! negative regulation of binding GO:0051100 58 36 0,000 0,09992877 0,11744312 ! organic ether metabolic process GO:0018904 46 36 0,000 0,09992877 0,11738314 ! tissue remodeling GO:0048771 62 36 0,000 0,09992877 0,11732322 ! neural tube development GO:0021915 50 36 0,000 0,09992877 0,11726336 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,09992877 0,11720356 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,09992877 0,11714382 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,09992877 0,11708415 ! glucan metabolic process GO:0044042 49 36 0,000 0,09992877 0,11702453 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,10255996 0,12004473 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,10255996 0,11998367 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,10255996 0,11992268 ! learning GO:0007612 67 37 0,000 0,10255996 0,11986174 ! ion transmembrane transport GO:0034220 56 37 0,000 0,10255996 0,11980086 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,10255996 0,11974005 ! regulation of protein secretion GO:0050708 51 37 0,000 0,10255996 0,1196793 ! amino acid activation GO:0043038 52 37 0,000 0,10255996 0,11961861 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,10255996 0,11955798 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,1051836 0,12255435 ! gliogenesis GO:0042063 71 38 0,000 0,1051836 0,12249229 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,1051836 0,1224303 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,1051836 0,12236838 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,1051836 0,12230651 ! phagocytosis GO:0006909 60 38 0,000 0,1051836 0,12224471 ! mesenchymal cell development GO:0014031 64 38 0,000 0,1051836 0,12218297 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,1051836 0,12212129 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,10779972 0,12509554 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,10779972 0,12503246 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,10779972 0,12496944 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,10779972 0,12490648 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,10779972 0,12484359 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,10779972 0,12478076 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,10779972 0,12471799 ! chromatin remodeling GO:0006338 68 39 0,000 0,10779972 0,12465528 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,10779972 0,12459264 ! JNK cascade GO:0007254 54 39 0,000 0,10779972 0,12453007 ! developmental growth GO:0048589 62 39 0,000 0,10779972 0,12446755 ! cell growth GO:0016049 61 39 0,000 0,10779972 0,1244051 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,11040835 0,12735165 ! response to calcium ion GO:0051592 58 40 0,000 0,11040835 0,12728782 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,11040835 0,12722405 ! regulation of tube size GO:0035150 60 40 0,000 0,11040835 0,12716034 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,11040835 0,12709669 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,11040835 0,12703311 ! peptide metabolic process GO:0006518 56 40 0,000 0,11040835 0,1269696 ! inner ear development GO:0048839 57 40 0,000 0,11040835 0,12690614 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,11040835 0,12684275 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,11040835 0,12677943 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,11040835 0,12671616 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,11040835 0,12665296 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,11040835 0,12658983 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,11300949 0,12950764 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,11300949 0,12944314 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,11300949 0,12937871 ! glucose transport GO:0015758 52 41 0,000 0,11300949 0,12931434 ! endosome transport GO:0016197 71 41 0,000 0,11300949 0,12925004 ! striated muscle contraction GO:0006941 62 41 0,000 0,11300949 0,1291858 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,11300949 0,12912162 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,11300949 0,12905751 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,11300949 0,12899346 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,11560318 0,13188855 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,11560318 0,13182316 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,11560318 0,13175784 ! cellular component disassembly GO:0022411 64 42 0,000 0,11560318 0,13169258 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,11560318 0,13162738 ! hexose transport GO:0008645 54 42 0,000 0,11560318 0,13156225 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,11560318 0,13149719 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,11560318 0,13143219 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,11560318 0,13136725 ! excretion GO:0007588 63 42 0,000 0,11560318 0,13130238 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,11560318 0,13123757 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,11560318 0,13117282 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,11560318 0,13110814 ! regulation of cell shape GO:0008360 78 42 0,000 0,11560318 0,13104352 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,11818943 0,13390921 ! leukocyte migration GO:0050900 60 43 0,000 0,11818943 0,13384327 ! neuromuscular process GO:0050905 79 43 0,000 0,11818943 0,13377741 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,11818943 0,1337116 ! tRNA processing GO:0008033 49 43 0,000 0,11818943 0,13364587 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,11818943 0,13358019 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,11818943 0,13351458 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,12076827 0,13636083 ! glycolysis GO:0006096 53 44 0,000 0,12076827 0,13629392 ! regulation of action potential GO:0001508 71 44 0,000 0,12076827 0,13622708 ! regulation of ion transport GO:0043269 57 44 0,000 0,12076827 0,1361603 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,12076827 0,13609359 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,12076827 0,13602694 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,12076827 0,13596036 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,12076827 0,13589384 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,12076827 0,13582739 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,12076827 0,13576101 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,12076827 0,13569468 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,12076827 0,13562843 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,12333971 0,13844867 ! positive regulation of defense response GO:0031349 59 45 0,000 0,12333971 0,13838114 ! regulation of translational initiation GO:0006446 64 45 0,000 0,12333971 0,13831367 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,12333971 0,13824626 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,12333971 0,13817893 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,12590378 0,14098281 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,12590378 0,14091421 ! cell redox homeostasis GO:0045454 63 46 0,000 0,12590378 0,14084567 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,12590378 0,1407772 ! regulation of ossification GO:0030278 71 46 0,000 0,12590378 0,14070879 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,12590378 0,14064045 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,1284605 0,14342677 ! viral infectious cycle GO:0019058 71 47 0,000 0,1284605 0,14335718 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,1284605 0,14328765 ! endocrine system development GO:0035270 83 47 0,000 0,1284605 0,1432182 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,1284605 0,14314881 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,1284605 0,14307949 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,1284605 0,14301023 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,1284605 0,14294105 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,1284605 0,14287193 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,1284605 0,14280287 ! chloride transport GO:0006821 67 48 0,000 0,13100988 0,14556653 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,13100988 0,14549625 ! response to temperature stimulus GO:0009266 62 48 0,000 0,13100988 0,14542603 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,13100988 0,14535587 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,13100988 0,14528579 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,13100988 0,14521577 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,13100988 0,14514582 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,13100988 0,14507594 ! regulation of endocytosis GO:0030100 63 48 0,000 0,13100988 0,14500612 ! nuclear export GO:0051168 69 48 0,000 0,13100988 0,14493638 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,13100988 0,14486669 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,13100988 0,14479708 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,13355195 0,14753578 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,13355195 0,14746495 ! sensory perception of smell GO:0007608 61 49 0,000 0,13355195 0,14739419 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,13355195 0,1473235 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,13355195 0,14725287 ! RNA elongation GO:0006354 62 49 0,000 0,13355195 0,14718232 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,13355195 0,14711183 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,13355195 0,1470414 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,13355195 0,14697105 ! cartilage development GO:0051216 70 49 0,000 0,13355195 0,14690076 ! regulation of actin filament length GO:0030832 72 50 0,000 0,13608674 0,14961735 ! ear development GO:0043583 72 50 0,000 0,13608674 0,14954586 ! membrane fusion GO:0006944 80 50 0,000 0,13608674 0,14947445 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,13608674 0,1494031 ! lipid modification GO:0030258 73 50 0,000 0,13608674 0,14933182 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,13608674 0,14926061 ! proton transport GO:0015992 75 50 0,000 0,13608674 0,14918946 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,13608674 0,14911839 ! positive regulation of secretion GO:0051047 71 51 0,000 0,13861425 0,1518156 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,13861425 0,15174334 ! hydrogen transport GO:0006818 77 51 0,000 0,13861425 0,15167115 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,13861425 0,15159903 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,13861425 0,15152698 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,13861425 0,151455 ! adult behavior GO:0030534 80 51 0,000 0,13861425 0,15138308 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,13861425 0,15131123 ! transition metal ion transport GO:0000041 74 52 0,000 0,14113451 0,15398926 ! regulation of cellular component size GO:0032535 74 52 0,000 0,14113451 0,15391625 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,14113451 0,1538433 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,14113451 0,15377043 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,14364754 0,15643435 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,14364754 0,15636031 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,14364754 0,15628635 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,14364754 0,15621245 ! kidney development GO:0001822 90 53 0,000 0,14364754 0,15613863 ! single fertilization GO:0007338 59 53 0,000 0,14364754 0,15606487 ! cell projection assembly GO:0030031 76 53 0,000 0,14364754 0,15599119 ! amino acid transport GO:0006865 84 54 0,000 0,14615336 0,15863744 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,14615336 0,15856261 ! regulation of mitosis GO:0007088 84 54 0,000 0,14615336 0,15848785 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,14615336 0,15841316 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,14615336 0,15833855 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,14615336 0,158264 ! DNA catabolic process GO:0006308 67 54 0,000 0,14615336 0,15818952 ! detection of external stimulus GO:0009581 66 54 0,000 0,14615336 0,15811511 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,14615336 0,15804078 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,14615336 0,15796651 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,14615336 0,15789231 ! exocytosis GO:0006887 74 55 0,000 0,14865199 0,16051624 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,14865199 0,16044091 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,14865199 0,16036566 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,15114346 0,16297701 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,15114346 0,16290064 ! carbohydrate transport GO:0008643 74 57 0,000 0,15362777 0,16550065 ! chromosome segregation GO:0007059 83 57 0,000 0,15362777 0,16542317 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,15362777 0,16534576 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,15362777 0,16526842 ! camera-type eye development GO:0043010 88 57 0,000 0,15362777 0,16519116 ! secondary metabolic process GO:0019748 84 57 0,000 0,15362777 0,16511396 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,15610496 0,167698 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,15610496 0,16761971 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,15610496 0,16754149 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,15857504 0,17011315 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,15857504 0,17003384 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,15857504 0,16995461 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,16103803 0,17251396 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,16103803 0,17243364 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,16103803 0,17235341 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,16103803 0,17227324 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,16103803 0,17219315 ! regulation of heart contraction GO:0008016 91 60 0,000 0,16103803 0,17211314 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,16103803 0,17203319 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,16103803 0,17195333 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,16349395 0,1744947 ! meiosis GO:0007126 96 61 0,000 0,16349395 0,17441377 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,16349395 0,17433291 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,16349395 0,17425213 ! urogenital system development GO:0001655 101 61 0,000 0,16349395 0,17417142 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,16349395 0,17409078 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,16349395 0,17401022 ! extracellular matrix organization GO:0030198 103 61 0,000 0,16349395 0,17392974 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,16349395 0,17384932 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,16349395 0,17376899 ! amine catabolic process GO:0009310 90 62 0,000 0,16594282 0,1762903 ! neurotransmitter transport GO:0006836 81 62 0,000 0,16594282 0,17620891 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,16594282 0,17612759 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,16594282 0,17604635 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,16594282 0,17596519 ! meiotic cell cycle GO:0051321 97 62 0,000 0,16594282 0,1758841 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,16838467 0,17839002 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,16838467 0,17830789 ! regulation of lipase activity GO:0060191 109 63 0,000 0,16838467 0,17822583 ! appendage morphogenesis GO:0035107 93 64 0,000 0,1708195 0,1807198 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,1708195 0,18063671 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,1708195 0,1805537 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,1708195 0,18047076 ! hexose catabolic process GO:0019320 82 64 0,000 0,1708195 0,1803879 ! adaptive immune response GO:0002250 94 64 0,000 0,1708195 0,18030512 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 0,000 0,17324735 0,1827839 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,17324735 0,18270009 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,17324735 0,18261636 ! defense response to bacterium GO:0042742 73 65 0,000 0,17324735 0,18253271 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,17324735 0,18244913 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,17324735 0,18236563 ! activation of immune response GO:0002253 83 65 0,000 0,17324735 0,1822822 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,17566822 0,18474482 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,17566822 0,18466038 ! antigen processing and presentation GO:0019882 96 66 0,000 0,17566822 0,18457602 ! axon guidance GO:0007411 99 66 0,000 0,17566822 0,18449174 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,17808215 0,18694155 ! acute inflammatory response GO:0002526 92 68 0,000 0,18048914 0,18938186 ! learning or memory GO:0007611 123 68 0,000 0,18048914 0,1892955 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,18048914 0,18920922 ! inorganic anion transport GO:0015698 93 68 0,000 0,18048914 0,18912302 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,18288923 0,19155065 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,18288923 0,19146346 ! response to metal ion GO:0010038 103 70 0,000 0,18528242 0,1938806 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,18528242 0,19379243 ! humoral immune response GO:0006959 86 70 0,000 0,18528242 0,19370435 ! eye development GO:0001654 111 70 0,000 0,18528242 0,19361634 ! amine transport GO:0015837 101 70 0,000 0,18528242 0,19352841 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,18528242 0,19344056 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,18528242 0,19335279 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,18766874 0,19575424 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,18766874 0,1956655 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,18766874 0,19557684 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,18766874 0,19548827 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,18766874 0,19539977 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,1900482 0,19778772 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,1900482 0,19769827 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,1900482 0,19760889 ! negative regulation of transport GO:0051051 116 73 0,000 0,19242084 0,19998551 ! regulation of blood pressure GO:0008217 107 73 0,000 0,19242084 0,19989518 ! tube morphogenesis GO:0035239 118 73 0,000 0,19242084 0,19980493 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,19242084 0,19971477 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,19242084 0,19962468 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,19478666 0,20198797 ! digestion GO:0007586 97 74 0,000 0,19478666 0,20189694 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,19478666 0,20180599 ! blood coagulation GO:0007596 116 75 0,000 0,19714568 0,20415806 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,19714568 0,20406618 ! regulation of ligase activity GO:0051340 114 75 0,000 0,19714568 0,20397439 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,19714568 0,20388267 ! amine biosynthetic process GO:0009309 97 76 0,000 0,19949793 0,20622258 ! tRNA metabolic process GO:0006399 95 76 0,000 0,19949793 0,20612993 ! regulation of protein transport GO:0051223 114 76 0,000 0,19949793 0,20603737 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,20184342 0,20836618 ! gland development GO:0048732 148 77 0,000 0,20184342 0,2082727 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,20184342 0,20817931 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,20184342 0,208086 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,20418217 0,21040277 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,20418217 0,21030855 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,20418217 0,21021441 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,2065142 0,21252021 ! cellular respiration GO:0045333 107 79 0,000 0,2065142 0,21242516 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,2065142 0,2123302 ! regulation of lyase activity GO:0051339 133 79 0,000 0,2065142 0,21223533 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,2065142 0,21214054 ! chromatin assembly GO:0031497 102 80 0,000 0,20883954 0,21443345 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,20883954 0,21433777 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,20883954 0,21424216 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 0,000 0,20883954 0,21414665 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,21115819 0,21642773 ! hemostasis GO:0007599 125 81 0,000 0,21115819 0,21633133 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,21115819 0,21623501 ! regulation of neurological system process GO:0031644 122 81 0,000 0,21115819 0,21613878 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,21115819 0,21604263 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,21347018 0,21831099 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,21347018 0,21821396 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,21577552 0,22047255 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,21577552 0,22037465 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,21577552 0,22027683 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,21807424 0,22252474 ! rRNA metabolic process GO:0016072 107 85 0,000 0,22036636 0,22476391 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,22036636 0,22466428 ! regulation of protein localization GO:0032880 132 85 0,000 0,22036636 0,22456474 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,22036636 0,22446529 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,22265189 0,22669293 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,22265189 0,22659263 ! nucleosome organization GO:0034728 114 87 0,000 0,22493084 0,22881068 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,22493084 0,22870952 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,22493084 0,22860846 ! female pregnancy GO:0007565 130 87 0,000 0,22493084 0,22850748 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,22720325 0,23071412 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,22720325 0,2306123 ! interphase GO:0051325 159 88 0,000 0,22720325 0,23051058 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,22720325 0,23040894 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,22720325 0,2303074 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,22946913 0,23250176 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,22946913 0,23239938 ! regulation of T cell activation GO:0050863 128 89 0,000 0,22946913 0,23229709 ! hormone metabolic process GO:0042445 121 90 0,000 0,23172849 0,23448109 ! ATP metabolic process GO:0046034 137 91 0,000 0,23398135 0,2366566 ! response to virus GO:0009615 122 91 0,000 0,23398135 0,23655258 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,23622774 0,23871872 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,23622774 0,23861388 ! positive regulation of immune response GO:0050778 121 92 0,000 0,23622774 0,23850914 ! DNA recombination GO:0006310 146 92 0,000 0,23622774 0,23840448 ! sulfur metabolic process GO:0006790 118 92 0,000 0,23622774 0,23829992 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,23846767 0,24045403 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,23846767 0,24034866 ! electron transport chain GO:0022900 123 94 0,000 0,24070116 0,24249351 ! response to oxidative stress GO:0006979 141 94 0,000 0,24070116 0,24238734 ! angiogenesis GO:0001525 149 95 0,000 0,24292823 0,24452295 ! carboxylic acid transport GO:0046942 147 95 0,000 0,24292823 0,24441598 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,24514889 0,24654239 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,24514889 0,24643464 ! protein maturation GO:0051604 129 96 0,000 0,24514889 0,24632698 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,24736317 0,24844336 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,24736317 0,24833491 ! calcium ion transport GO:0006816 167 99 0,000 0,25177263 0,25265142 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,25177263 0,25254124 ! regulation of translation GO:0006417 151 100 0,000 0,25396786 0,25463212 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,25396786 0,25452117 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,25396786 0,25441031 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,25396786 0,25429955 ! divalent metal ion transport GO:0070838 171 100 0,000 0,25396786 0,25418889 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,25396786 0,25407833 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,25396786 0,25396786