pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6241-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of mitochondrial membrane permeability GO:0046902 15 5 2,000 1,136E-07 2,776E-04 ! protein targeting to ER GO:0045047 25 9 2,000 9,483E-07 1,158E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 4,075E-06 3,319E-03 ! neuron recognition GO:0008038 40 16 2,000 6,249E-06 3,817E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,264E-05 6,175E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,529E-05 0,0102971 ! mitochondrial membrane organization GO:0007006 60 27 2,000 3,206E-05 0,01118763 ! positive regulation of glycolysis GO:0045821 13 5 1,000 5,106E-05 0,01559396 ! skeletal myofibril assembly GO:0014866 12 5 1,000 5,106E-05 0,0138613 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 5,106E-05 0,01247517 ! muscle cell proliferation GO:0033002 12 5 1,000 5,106E-05 0,01134106 ! mesoderm formation GO:0001707 73 32 2,000 5,391E-05 0,01097594 ! formation of primary germ layer GO:0001704 76 34 2,000 6,483E-05 0,01218323 ! mesoderm morphogenesis GO:0048332 80 35 2,000 7,079E-05 0,01235328 ! activation of MAPKKK activity GO:0000185 12 6 1,000 7,648E-05 0,01245669 ! neuronal ion channel clustering GO:0045161 15 6 1,000 7,648E-05 0,01167815 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 7,648E-05 0,0109912 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 7,648E-05 0,01038057 ! protein targeting to membrane GO:0006612 75 36 2,000 7,71E-05 9,914E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 1,069E-04 0,01306016 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,069E-04 0,01243824 ! male sex determination GO:0030238 15 7 1,000 1,069E-04 0,01187287 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,069E-04 0,01135666 ! B cell lineage commitment GO:0002326 21 7 1,000 1,069E-04 0,01088346 ! T cell lineage commitment GO:0002360 16 7 1,000 1,069E-04 0,01044812 ! axonal fasciculation GO:0007413 19 7 1,000 1,069E-04 0,01004627 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,142E-04 0,01033034 ! striated muscle cell differentiation GO:0051146 91 43 2,000 1,317E-04 0,01149443 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,423E-04 0,01199156 ! regulation of defense response to virus by virus GO:0050690 22 8 1,000 1,423E-04 0,01159184 ! ER overload response GO:0006983 13 8 1,000 1,423E-04 0,01121791 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 1,000 1,423E-04 0,01086735 ! protein retention in ER lumen GO:0006621 14 8 1,000 1,423E-04 0,01053804 ! cardiac muscle cell differentiation GO:0055007 31 8 1,000 1,423E-04 0,01022809 ! response to tumor cell GO:0002347 16 8 1,000 1,423E-04 9,936E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,423E-04 9,66E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,613E-04 0,01064699 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,827E-04 0,01174873 ! regulation of glycolysis GO:0006110 20 9 1,000 1,827E-04 0,01144748 ! retinoic acid receptor signaling pathway GO:0048384 16 9 1,000 1,827E-04 0,0111613 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 1,827E-04 0,01088907 ! mitochondrial transport GO:0006839 94 48 2,000 1,831E-04 0,01065192 ! regulation of developmental growth GO:0048638 16 10 1,000 2,281E-04 0,01295904 ! COPI coating of Golgi vesicle GO:0048205 23 10 1,000 2,281E-04 0,01266452 GO:0048200|Golgi transport vesicle coating, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 2,281E-04 0,01238309 ! protein heterooligomerization GO:0051291 17 10 1,000 2,281E-04 0,01211389 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 2,281E-04 0,01185615 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,281E-04 0,01160914 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 2,46E-04 0,0122651 ! cell recognition GO:0008037 98 55 2,000 2,746E-04 0,01341701 ! Golgi vesicle budding GO:0048194 26 11 1,000 2,784E-04 0,01333455 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,784E-04 0,01307811 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,784E-04 0,01283136 ! positive regulation of neuron differentiation GO:0045666 22 11 1,000 2,784E-04 0,01259374 ! cardiac cell differentiation GO:0035051 36 11 1,000 2,784E-04 0,01236476 ! regulation of embryonic development GO:0045995 35 11 1,000 2,784E-04 0,01214396 ! regulation of DNA replication GO:0006275 105 56 2,000 2,897E-04 0,01241512 ! heart morphogenesis GO:0003007 105 57 2,000 3,053E-04 0,0128578 ! gastrulation GO:0007369 122 58 2,000 3,214E-04 0,01330749 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 3,336E-04 0,01358111 ! virus-host interaction GO:0019048 30 12 1,000 3,336E-04 0,01335847 ! histone acetylation GO:0016573 27 12 1,000 3,336E-04 0,01314301 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,336E-04 0,01293439 ! response to X-ray GO:0010165 28 13 1,000 3,936E-04 0,01502499 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,936E-04 0,01479384 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! mesoderm development GO:0007498 128 63 2,000 4,102E-04 0,01518505 ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 1,000 4,585E-04 0,01671951 ! regulation of cellular pH GO:0030641 27 14 1,000 4,585E-04 0,01647363 ! response to gamma radiation GO:0010332 30 14 1,000 4,585E-04 0,01623488 ! regulation of axon extension GO:0030516 43 14 1,000 4,585E-04 0,01600296 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,283E-04 0,01817796 ! vesicle coating GO:0006901 38 15 1,000 5,283E-04 0,01792548 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 5,283E-04 0,01767993 ! G1/S transition checkpoint GO:0031575 37 15 1,000 5,283E-04 0,01744101 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 5,283E-04 0,01720846 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,029E-04 0,01937935 ! intermediate filament-based process GO:0045103 36 16 1,000 6,029E-04 0,01912767 ! axon cargo transport GO:0008088 46 16 1,000 6,029E-04 0,01888244 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,029E-04 0,01864342 ! activation of MAPKK activity GO:0000186 43 17 1,000 6,823E-04 0,02083425 ! regulation of survival gene product expression GO:0045884 38 17 1,000 6,823E-04 0,02057704 ! membrane budding GO:0006900 42 17 1,000 6,823E-04 0,0203261 ! positive regulation of anti-apoptosis GO:0045768 47 18 1,000 7,664E-04 0,02255796 ! regulation of defense response to virus GO:0050688 35 18 1,000 7,664E-04 0,02228941 ! response to retinoic acid GO:0032526 31 18 1,000 7,664E-04 0,02202718 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 7,664E-04 0,02177105 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 1,000 7,664E-04 0,02152081 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 7,664E-04 0,02127626 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 7,664E-04 0,0210372 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 7,664E-04 0,02080345 ! protein oligomerization GO:0051259 149 79 2,000 7,958E-04 0,02136443 ! neuron maturation GO:0042551 46 19 1,000 8,553E-04 0,02271185 ! response to vitamin A GO:0033189 32 19 1,000 8,553E-04 0,02246763 ! muscle cell differentiation GO:0042692 178 81 2,000 8,558E-04 0,02224198 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 1,000 9,489E-04 0,02440237 ! protein amino acid acetylation GO:0006473 41 20 1,000 9,489E-04 0,02414818 ! response to vitamin GO:0033273 36 20 1,000 9,489E-04 0,02389923 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 9,489E-04 0,02365536 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 39 21 1,000 1,047E-03 0,02584306 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 1,047E-03 0,02558463 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,047E-03 0,02533132 ! mitochondrion organization GO:0007005 159 87 2,000 1,053E-03 0,02521587 ! microtubule-based transport GO:0010970 59 22 1,000 1,15E-03 0,02728303 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,15E-03 0,02702069 ! cellular response to starvation GO:0009267 37 22 1,000 1,15E-03 0,02676335 ! cell aging GO:0007569 48 22 1,000 1,15E-03 0,02651087 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 1,15E-03 0,0262631 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,258E-03 0,02845593 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 1,258E-03 0,02819486 ! vesicle targeting GO:0006903 49 23 1,000 1,258E-03 0,02793855 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 1,258E-03 0,02768685 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 1,258E-03 0,02743964 GO:0060415|muscle tissue morphogenesis, ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,37E-03 0,02962544 ! sex determination GO:0007530 48 24 1,000 1,37E-03 0,02936557 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,37E-03 0,02911022 ! response to protein stimulus GO:0051789 158 96 2,000 1,398E-03 0,02945196 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 1,441E-03 0,03008297 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 1,487E-03 0,03079156 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,487E-03 0,03053281 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,487E-03 0,03027837 ! interaction with host GO:0051701 66 25 1,000 1,487E-03 0,03002814 ! skeletal muscle tissue development GO:0007519 223 100 2,000 1,572E-03 0,03148571 GO:0060538|skeletal muscle organ development, ! protein amino acid alkylation GO:0008213 59 26 1,000 1,609E-03 0,03195429 GO:0006479|protein amino acid methylation, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,609E-03 0,03169659 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,609E-03 0,03144302 ! negative regulation of cell development GO:0010721 83 26 1,000 1,609E-03 0,03119347 GO:0050768|negative regulation of neurogenesis, ! regulation of multi-organism process GO:0043900 45 26 1,000 1,609E-03 0,03094786 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,735E-03 0,03311362 ! response to starvation GO:0042594 47 27 1,000 1,735E-03 0,03285692 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,735E-03 0,03260418 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 1,866E-03 0,03479274 ! protein amino acid acylation GO:0043543 59 28 1,000 1,866E-03 0,03452916 ! base-excision repair GO:0006284 41 28 1,000 1,866E-03 0,03426954 ! regulation of response to biotic stimulus GO:0002831 52 28 1,000 1,866E-03 0,0340138 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,866E-03 0,03376184 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,001E-03 0,03594297 ! response to organic cyclic substance GO:0014070 58 29 1,000 2,001E-03 0,03568061 ! somitogenesis GO:0001756 52 29 1,000 2,001E-03 0,03542206 ! synaptogenesis GO:0007416 46 29 1,000 2,001E-03 0,03516722 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 2,001E-03 0,03491603 ! myofibril assembly GO:0030239 50 30 1,000 2,141E-03 0,03708992 GO:0055002|striated muscle cell development, ! ovulation cycle process GO:0022602 55 31 1,000 2,285E-03 0,03931056 ! male gonad development GO:0008584 56 31 1,000 2,285E-03 0,03903566 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 2,285E-03 0,03876458 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 2,285E-03 0,03849724 ! muscle cell development GO:0055001 52 32 1,000 2,434E-03 0,04072232 ! ovulation cycle GO:0042698 57 32 1,000 2,434E-03 0,0404453 ! positive regulation of catabolic process GO:0009896 72 32 1,000 2,434E-03 0,04017202 ! regulation of pH GO:0006885 56 33 1,000 2,587E-03 0,04241413 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 2,587E-03 0,04213137 ! response to ionizing radiation GO:0010212 74 33 1,000 2,587E-03 0,04185235 ! regulation of axonogenesis GO:0050770 86 33 1,000 2,587E-03 0,04157701 ! establishment of vesicle localization GO:0051650 67 33 1,000 2,587E-03 0,04130526 ! regulation of ARF GTPase activity GO:0032312 73 34 1,000 2,744E-03 0,04353759 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 2,744E-03 0,0432567 ! DNA damage checkpoint GO:0000077 78 35 1,000 2,907E-03 0,04551703 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 2,907E-03 0,04522712 ! vesicle localization GO:0051648 70 35 1,000 2,907E-03 0,04494087 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 3,073E-03 0,04721549 ! actomyosin structure organization GO:0031032 68 37 1,000 3,244E-03 0,04952847 ! maintenance of protein location in cell GO:0032507 89 37 1,000 3,244E-03 0,04922084 ! female gonad development GO:0008585 71 37 1,000 3,244E-03 0,04891701 ! regulation of microtubule-based process GO:0032886 86 37 1,000 3,244E-03 0,04861691 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 3,419E-03 0,05092979 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 3,419E-03 0,05062113 ! DNA integrity checkpoint GO:0031570 82 38 1,000 3,419E-03 0,05031618 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 3,419E-03 0,05001488 ! regulation of neuron projection development GO:0010975 102 39 1,000 3,598E-03 0,0523274 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 3,598E-03 0,05201777 ! carbohydrate homeostasis GO:0033500 59 39 1,000 3,598E-03 0,05171178 GO:0042593|glucose homeostasis, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 3,598E-03 0,05140938 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 3,782E-03 0,05372128 GO:0046660|female sex differentiation, ! mRNA catabolic process GO:0006402 79 41 1,000 3,97E-03 0,05606708 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 3,97E-03 0,05574486 ! maintenance of protein location GO:0045185 95 41 1,000 3,97E-03 0,05542632 ! T cell differentiation GO:0030217 93 42 1,000 4,163E-03 0,05778177 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 4,359E-03 0,06016932 GO:0090047|positive regulation of transcription regulator activity, ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 4,359E-03 0,05983129 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 4,359E-03 0,05949704 ! segmentation GO:0035282 78 43 1,000 4,359E-03 0,0591665 ! neuron migration GO:0001764 85 43 1,000 4,359E-03 0,05883961 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 4,56E-03 0,06121258 ! double-strand break repair GO:0006302 85 44 1,000 4,56E-03 0,06087809 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 4,765E-03 0,06327014 ! biopolymer methylation GO:0043414 91 45 1,000 4,765E-03 0,06292814 ! B cell differentiation GO:0030183 124 45 1,000 4,765E-03 0,06258982 ! maintenance of location in cell GO:0051651 101 45 1,000 4,765E-03 0,06225511 ! response to insulin stimulus GO:0032868 98 47 1,000 5,188E-03 0,06741717 ! positive regulation of DNA binding GO:0043388 83 48 1,000 5,406E-03 0,06987323 ! male sex differentiation GO:0046661 93 48 1,000 5,406E-03 0,06950547 ! methylation GO:0032259 97 48 1,000 5,406E-03 0,06914157 ! regulation of ARF protein signal transduction GO:0032012 115 50 1,000 5,853E-03 0,07447667 ! activation of caspase activity GO:0006919 95 50 1,000 5,853E-03 0,07409078 ! regulation of cell projection organization GO:0031344 135 51 1,000 6,083E-03 0,07660462 ! positive regulation of binding GO:0051099 88 52 1,000 6,317E-03 0,07914376 ! histone modification GO:0016570 104 52 1,000 6,317E-03 0,07873996 ! positive regulation of growth GO:0045927 96 53 1,000 6,555E-03 0,0812928 ! vesicle organization GO:0016050 127 53 1,000 6,555E-03 0,08088223 ! synapse organization GO:0050808 102 53 1,000 6,555E-03 0,08047579 ! covalent chromatin modification GO:0016569 115 54 1,000 6,797E-03 0,08303098 ! RNA catabolic process GO:0006401 103 55 1,000 7,044E-03 0,0856096 ! cell maturation GO:0048469 107 55 1,000 7,044E-03 0,08518579 ! response to UV GO:0009411 120 55 1,000 7,044E-03 0,08476616 ! skeletal muscle fiber development GO:0048741 130 56 1,000 7,294E-03 0,08734625 ! positive regulation of caspase activity GO:0043280 108 57 1,000 7,548E-03 0,08994862 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 7,548E-03 0,08951198 ! nucleotide-excision repair GO:0006289 91 57 1,000 7,548E-03 0,08907956 ! positive regulation of cell migration GO:0030335 137 58 1,000 7,806E-03 0,09168259 ! aging GO:0007568 112 58 1,000 7,806E-03 0,09124392 ! maintenance of location GO:0051235 124 58 1,000 7,806E-03 0,09080943 ! establishment of organelle localization GO:0051656 122 59 1,000 8,068E-03 0,09341291 ! viral reproductive process GO:0022415 132 62 1,000 8,878E-03 0,10230141 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 8,878E-03 0,10182113 ! regulation of mitosis GO:0007088 112 63 1,000 9,155E-03 0,10451457 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 9,437E-03 0,10722671 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 9,437E-03 0,10673029 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 9,437E-03 0,10623845 ! multicellular organism reproduction GO:0032504 123 65 1,000 9,722E-03 0,10894828 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 1,000 9,722E-03 0,1084508 ! gonad development GO:0008406 115 66 1,000 0,01001106 0,11116829 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01030397 0,11390312 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01030397 0,11339004 ! chromosome segregation GO:0007059 127 67 1,000 0,01030397 0,11288157 ! viral reproduction GO:0016032 142 68 1,000 0,01060065 0,1156133 ! negative regulation of cell size GO:0045792 144 69 1,000 0,01090109 0,11836156 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,01090109 0,11783784 ! lung development GO:0030324 165 69 1,000 0,01090109 0,11731873 ! developmental maturation GO:0021700 128 69 1,000 0,01090109 0,11680417 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,01120526 0,11953911 ! germ cell development GO:0007281 133 70 1,000 0,01120526 0,11901938 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01134315 0,1199624 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01134315 0,11944532 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01134315 0,11893268 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01134315 0,11842442 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01134315 0,11792049 ! neuron fate determination GO:0048664 7 5 0,000 0,01134315 0,11742082 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01134315 0,11692538 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01134315 0,11643409 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01134315 0,11594692 ! polyol transport GO:0015791 12 5 0,000 0,01134315 0,11546381 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01134315 0,11498471 ! response to superoxide GO:0000303 10 5 0,000 0,01134315 0,11450956 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01134315 0,11403833 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01134315 0,11357096 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01134315 0,1131074 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01134315 0,11264762 ! female meiosis GO:0007143 10 5 0,000 0,01134315 0,11219156 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01134315 0,11173917 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01134315 0,11129042 ! hypothalamus development GO:0021854 9 5 0,000 0,01134315 0,11084526 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01134315 0,11040364 ! cobalt ion transport GO:0006824 11 5 0,000 0,01134315 0,10996553 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01134315 0,10953089 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01134315 0,10909966 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01134315 0,10867182 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01134315 0,10824732 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01134315 0,10782612 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01134315 0,10740819 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01134315 0,10699349 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01134315 0,10658198 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01134315 0,10617362 ! transposition GO:0032196 9 5 0,000 0,01134315 0,10576837 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01134315 0,10536621 ! negative chemotaxis GO:0050919 16 5 0,000 0,01134315 0,1049671 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01134315 0,104571 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01134315 0,10417787 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01134315 0,10378769 ! behavioral response to pain GO:0048266 10 5 0,000 0,01134315 0,10340043 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01134315 0,10301604 ! Notch receptor processing GO:0007220 11 5 0,000 0,01134315 0,1026345 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01134315 0,10225577 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01134315 0,10187983 ! micturition GO:0060073 9 5 0,000 0,01134315 0,10150665 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01134315 0,10113618 ! copulation GO:0007620 9 5 0,000 0,01134315 0,10076841 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01134315 0,10040331 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01134315 0,10004085 ! bioluminescence GO:0008218 9 5 0,000 0,01134315 0,09968099 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01134315 0,09932371 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01134315 0,09896898 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01134315 0,09861678 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01134315 0,09826707 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01134315 0,09791984 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01134315 0,09757505 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01134315 0,09723268 ! grooming behavior GO:0007625 6 5 0,000 0,01134315 0,09689271 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01134315 0,0965551 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01134315 0,09621984 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01134315 0,0958869 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01134315 0,09555626 ! response to protozoan GO:0001562 13 5 0,000 0,01134315 0,09522788 ! lymph vessel development GO:0001945 10 5 0,000 0,01134315 0,09490176 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01134315 0,09457786 ! endochondral ossification GO:0001958 17 5 0,000 0,01134315 0,09425617 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01134315 0,09393666 ! single strand break repair GO:0000012 8 5 0,000 0,01134315 0,0936193 ! parathyroid gland development GO:0060017 14 5 0,000 0,01134315 0,09330409 ! anagen GO:0042640 7 5 0,000 0,01134315 0,09299099 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01134315 0,09267998 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01134315 0,09237105 ! cytokine secretion GO:0050663 15 5 0,000 0,01134315 0,09206417 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01134315 0,09175932 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01134315 0,09145648 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01134315 0,09115564 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01134315 0,09085677 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01134315 0,09055985 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01134315 0,09026487 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01134315 0,0899718 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01134315 0,08968063 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01134315 0,08939134 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01134315 0,0891039 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01134315 0,08881831 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01134315 0,08853455 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01134315 0,08825259 ! microvillus organization GO:0032528 8 5 0,000 0,01134315 0,08797243 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01134315 0,08769403 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01134315 0,08741739 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01134315 0,0871425 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01134315 0,08686932 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01134315 0,08659786 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01134315 0,08632808 ! polyol catabolic process GO:0046174 9 5 0,000 0,01134315 0,08605998 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01134315 0,08579354 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01134315 0,08552875 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01134315 0,08526558 ! muscle cell migration GO:0014812 8 5 0,000 0,01134315 0,08500403 ! mitochondrial fission GO:0000266 8 5 0,000 0,01134315 0,08474408 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01134315 0,08448571 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01134315 0,08422892 ! mRNA transcription GO:0009299 10 5 0,000 0,01134315 0,08397368 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01134315 0,08371998 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01134315 0,08346781 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01134315 0,08321716 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01134315 0,08296801 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01134315 0,08272034 ! monocyte activation GO:0042117 10 5 0,000 0,01134315 0,08247415 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01134315 0,08222942 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01134315 0,08198614 ! response to food GO:0032094 6 5 0,000 0,01134315 0,08174429 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01134315 0,08150387 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01134315 0,08126485 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01134315 0,08102723 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01134315 0,080791 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01134315 0,08055615 ! forebrain neuron development GO:0021884 13 5 0,000 0,01134315 0,08032265 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01134315 0,0800905 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01134315 0,07985969 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01134315 0,07963021 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01134315 0,07940205 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01134315 0,07917518 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01134315 0,07894961 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01134315 0,07872532 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01134315 0,07850231 ! lipid glycosylation GO:0030259 7 5 0,000 0,01134315 0,07828055 ! nucleobase transport GO:0015851 6 5 0,000 0,01134315 0,07806004 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01134315 0,07784077 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01134315 0,07762273 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01134315 0,07740591 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01134315 0,07719029 ! basic amino acid transport GO:0015802 12 5 0,000 0,01134315 0,07697587 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01134315 0,07676264 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01134315 0,07655059 ! actin nucleation GO:0045010 11 5 0,000 0,01134315 0,07633971 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01134315 0,07612998 ! depurination GO:0045007 5 5 0,000 0,01134315 0,07592141 ! depyrimidination GO:0045008 10 5 0,000 0,01134315 0,07571397 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01134315 0,07550767 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01134315 0,07530248 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01134315 0,07509841 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01134315 0,07489544 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01134315 0,07469357 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01134315 0,07449278 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01134315 0,07429307 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01134315 0,07409442 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01134315 0,07389684 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01134315 0,0737003 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01134315 0,07350481 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01134315 0,07331035 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01134315 0,07311692 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01134315 0,07292451 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01134315 0,07273311 ! response to arsenic GO:0046685 11 5 0,000 0,01134315 0,07254271 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01134315 0,0723533 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01134315 0,07216488 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01134315 0,07197744 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01134315 0,07179097 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01134315 0,07160546 ! response to mercury ion GO:0046689 8 5 0,000 0,01134315 0,07142091 ! response to cadmium ion GO:0046686 7 5 0,000 0,01134315 0,07123731 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01134315 0,07105465 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01134315 0,07087293 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01134315 0,07069213 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01134315 0,07051225 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01134315 0,07033328 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01134315 0,07015523 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01134315 0,06997807 ! decidualization GO:0046697 11 5 0,000 0,01134315 0,0698018 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01134315 0,06962642 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01134315 0,06945192 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01134315 0,06927829 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01134315 0,06910552 ! embryonic cleavage GO:0040016 6 5 0,000 0,01134315 0,06893362 ! peroxisome fission GO:0016559 5 5 0,000 0,01134315 0,06876257 ! histone demethylation GO:0016577 13 5 0,000 0,01134315 0,06859236 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01134315 0,068423 ! mitotic recombination GO:0006312 9 5 0,000 0,01134315 0,06825447 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01134315 0,06808677 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01134315 0,06791989 ! metaphase plate congression GO:0051310 7 5 0,000 0,01134315 0,06775382 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01134315 0,06758857 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01134315 0,06742412 ! enteric nervous system development GO:0048484 8 5 0,000 0,01134315 0,06726047 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01134315 0,06709761 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01134315 0,06693554 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01134315 0,06677425 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01134315 0,06661374 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01134315 0,06645399 ! B cell homeostasis GO:0001782 13 5 0,000 0,01134315 0,06629501 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01134315 0,06613679 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01134315 0,06597932 ! metaphase GO:0051323 11 5 0,000 0,01134315 0,0658226 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01134315 0,06566662 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01134315 0,06551138 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01134315 0,06535687 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01134315 0,06520309 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01134315 0,06505003 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01134315 0,06489769 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01134315 0,06474606 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01134315 0,06459514 ! response to redox state GO:0051775 6 5 0,000 0,01134315 0,06444492 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01134315 0,06429539 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01134315 0,06414656 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01134315 0,06399842 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01134315 0,06385095 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01134315 0,06370417 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01134315 0,06355806 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01134315 0,06341262 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01134315 0,06326784 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01134315 0,06312372 ! striatum development GO:0021756 14 5 0,000 0,01134315 0,06298026 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01134315 0,06283745 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01134315 0,06269528 ! glial cell migration GO:0008347 10 5 0,000 0,01134315 0,06255376 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01134315 0,06241287 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01134315 0,06227262 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01134315 0,06213299 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01134315 0,06199399 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01134315 0,06185561 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01134315 0,06171785 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01134315 0,0615807 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01134315 0,06144416 ! neuroprotection GO:0043526 8 5 0,000 0,01134315 0,06130822 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01134315 0,06117288 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01134315 0,06103814 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01134315 0,06090399 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01134315 0,06077043 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01134315 0,06063745 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01134315 0,06050505 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01134315 0,06037323 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01134315 0,06024199 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01134315 0,06011131 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01134315 0,0599812 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01134315 0,05985165 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01134315 0,05972266 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01134315 0,05959422 ! spindle assembly GO:0051225 6 5 0,000 0,01134315 0,05946634 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01134315 0,059339 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01134315 0,05921221 ! protein palmitoylation GO:0018345 12 5 0,000 0,01134315 0,05908596 ! drug metabolic process GO:0017144 7 5 0,000 0,01134315 0,05896024 ! stem cell division GO:0017145 11 5 0,000 0,01134315 0,05883506 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01134315 0,05871041 ! organ regeneration GO:0031100 7 5 0,000 0,01134315 0,05858629 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01134315 0,05846269 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01134315 0,05833961 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01151316 0,05908961 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,01151316 0,05896573 ! respiratory tube development GO:0030323 171 72 1,000 0,01182476 0,06043493 ! actin filament organization GO:0007015 167 72 1,000 0,01182476 0,06030876 ! B cell activation GO:0042113 179 72 1,000 0,01182476 0,06018312 ! regulation of immune effector process GO:0002697 156 73 1,000 0,01214005 0,06165934 ! regulation of caspase activity GO:0043281 136 74 1,000 0,012459 0,06314802 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,012459 0,06301728 ! respiratory system development GO:0060541 175 74 1,000 0,012459 0,06288708 ! organelle localization GO:0051640 155 74 1,000 0,012459 0,06275741 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01278161 0,06424993 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,01278161 0,064118 ! rhythmic process GO:0048511 142 75 1,000 0,01278161 0,06398661 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01310784 0,06548559 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01343769 0,06699647 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01343769 0,06686002 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01359648 0,06751262 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01359648 0,06737567 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01359648 0,06723929 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01359648 0,06710345 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01359648 0,06696816 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01359648 0,06683341 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01359648 0,06669921 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01359648 0,06656554 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01359648 0,06643241 ! response to oxygen radical GO:0000305 11 6 0,000 0,01359648 0,06629981 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01359648 0,06616774 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01359648 0,0660362 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01359648 0,06590517 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01359648 0,06577467 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01359648 0,06564468 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01359648 0,0655152 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01359648 0,06538623 ! forebrain regionalization GO:0021871 9 6 0,000 0,01359648 0,06525777 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01359648 0,06512982 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01359648 0,06500236 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01359648 0,0648754 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01359648 0,06474894 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01359648 0,06462297 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01359648 0,06449749 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01359648 0,06437249 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01359648 0,06424798 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01359648 0,06412395 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01359648 0,0640004 ! malate metabolic process GO:0006108 13 6 0,000 0,01359648 0,06387732 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01359648 0,06375472 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01359648 0,06363258 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01359648 0,06351091 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01359648 0,06338971 ! protein refolding GO:0042026 15 6 0,000 0,01359648 0,06326897 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01359648 0,06314868 ! opsonization GO:0008228 8 6 0,000 0,01359648 0,06302886 ! mating behavior GO:0007617 7 6 0,000 0,01359648 0,06290948 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01359648 0,06279056 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01359648 0,06267209 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01359648 0,06255406 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01359648 0,06243648 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01359648 0,06231934 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01359648 0,06220263 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01359648 0,06208637 ! toxin metabolic process GO:0009404 11 6 0,000 0,01359648 0,06197054 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01359648 0,06185513 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01359648 0,06174016 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01359648 0,06162562 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01359648 0,06151149 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01359648 0,06139779 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01359648 0,06128451 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01359648 0,06117165 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01359648 0,0610592 ! thymic T cell selection GO:0045061 16 6 0,000 0,01359648 0,06094717 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01359648 0,06083554 ! protein lipoylation GO:0009249 10 6 0,000 0,01359648 0,06072433 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01359648 0,06061352 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01359648 0,06050311 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01359648 0,0603931 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01359648 0,0602835 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01359648 0,06017429 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01359648 0,06006547 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01359648 0,05995705 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01359648 0,05984902 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01359648 0,05974138 ! hyperosmotic response GO:0006972 10 6 0,000 0,01359648 0,05963412 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01359648 0,05952725 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01359648 0,05942076 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01359648 0,05931466 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01359648 0,05920892 ! urea metabolic process GO:0019627 7 6 0,000 0,01359648 0,05910357 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01359648 0,05899859 ! neutrophil activation GO:0042119 7 6 0,000 0,01359648 0,05889398 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01359648 0,05878975 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01359648 0,05868588 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01359648 0,05858238 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01359648 0,05847924 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01359648 0,05837646 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01359648 0,05827405 ! neuron apoptosis GO:0051402 15 6 0,000 0,01359648 0,05817199 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01359648 0,05807029 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01359648 0,05796895 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01359648 0,05786796 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01359648 0,05776732 ! carnitine transport GO:0015879 10 6 0,000 0,01359648 0,05766703 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01359648 0,05756708 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01359648 0,05746749 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01359648 0,05736823 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01359648 0,05726932 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01359648 0,05717075 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01359648 0,05707252 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01359648 0,05697463 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01359648 0,05687707 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01359648 0,05677984 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01359648 0,05668295 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01359648 0,05658638 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01359648 0,05649015 ! response to UV-C GO:0010225 14 6 0,000 0,01359648 0,05639424 ! astrocyte development GO:0014002 16 6 0,000 0,01359648 0,05629866 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01359648 0,0562034 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01359648 0,05610846 ! interaction with symbiont GO:0051702 14 6 0,000 0,01359648 0,05601384 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01359648 0,05591954 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01359648 0,05582556 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01359648 0,05573189 ! response to copper ion GO:0046688 10 6 0,000 0,01359648 0,05563854 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01359648 0,0555455 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01359648 0,05545277 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01359648 0,05536034 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01359648 0,05526823 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01359648 0,05517642 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01359648 0,05508492 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01359648 0,05499372 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01359648 0,05490282 ! hair follicle maturation GO:0048820 8 6 0,000 0,01359648 0,05481222 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01359648 0,05472192 ! Schwann cell development GO:0014044 15 6 0,000 0,01359648 0,05463192 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01359648 0,05454221 ! response to pheromone GO:0019236 6 6 0,000 0,01359648 0,0544528 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01359648 0,05436368 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01359648 0,05427485 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01359648 0,05418631 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01359648 0,05409806 ! subpallium development GO:0021544 15 6 0,000 0,01359648 0,05401009 ! neural tube patterning GO:0021532 8 6 0,000 0,01359648 0,05392241 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01359648 0,05383502 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01359648 0,05374791 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01359648 0,05366108 ! G2 phase GO:0051319 16 6 0,000 0,01359648 0,05357453 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01359648 0,05348826 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01359648 0,05340226 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01359648 0,05331654 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01359648 0,0532311 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01359648 0,05314593 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01359648 0,05306103 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01359648 0,05297641 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01359648 0,05289205 ! receptor internalization GO:0031623 11 6 0,000 0,01359648 0,05280796 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01359648 0,05272414 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01359648 0,05264058 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01359648 0,05255729 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01359648 0,05247426 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01359648 0,05239149 ! protein deubiquitination GO:0016579 16 6 0,000 0,01359648 0,05230899 ! protein destabilization GO:0031648 9 6 0,000 0,01359648 0,05222674 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01359648 0,05214475 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01359648 0,05206302 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01359648 0,05198154 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01359648 0,05190032 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01359648 0,05181936 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01359648 0,05173864 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01359648 0,05165818 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01359648 0,05157796 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01359648 0,051498 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01359648 0,05141828 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01359648 0,05133881 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01359648 0,05125958 ! neural plate development GO:0001840 9 6 0,000 0,01359648 0,0511806 ! catecholamine transport GO:0051937 9 6 0,000 0,01359648 0,05110186 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01359648 0,05102336 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01359648 0,0509451 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01359648 0,05086709 ! maternal placenta development GO:0001893 12 6 0,000 0,01359648 0,05078931 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01359648 0,05071177 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01359648 0,05063446 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01359648 0,05055739 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01359648 0,05048056 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01359648 0,05040396 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01359648 0,05032759 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01359648 0,05025145 GO:0055081|anion homeostasis, ! fertilization GO:0009566 99 78 1,000 0,01377113 0,05082005 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,01444873 0,05324021 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,01444873 0,05316003 ! response to hypoxia GO:0001666 178 81 1,000 0,01479286 0,05434429 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01514051 0,05553793 ! protein import into nucleus GO:0006606 174 82 1,000 0,01514051 0,05545467 ! response to drug GO:0042493 149 83 1,000 0,01549167 0,0566559 ! response to oxygen levels GO:0070482 183 83 1,000 0,01549167 0,05657121 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,01549167 0,05648678 ! nuclear import GO:0051170 177 83 1,000 0,01549167 0,0564026 ! tRNA transcription GO:0009304 17 7 0,000 0,01584474 0,05760224 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01584474 0,05751665 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01584474 0,05743132 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01584474 0,05734623 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01584474 0,0572614 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01584474 0,05717682 ! sleep GO:0030431 16 7 0,000 0,01584474 0,05709249 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01584474 0,05700841 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01584474 0,05692457 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01584474 0,05684098 ! prostate gland development GO:0030850 14 7 0,000 0,01584474 0,05675764 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01584474 0,05667454 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01584474 0,05659168 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01584474 0,05650906 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01584474 0,05642669 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01584474 0,05634455 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01584474 0,05626266 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01584474 0,056181 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01584474 0,05609958 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01584474 0,05601839 ! glycolipid transport GO:0046836 11 7 0,000 0,01584474 0,05593744 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01584474 0,05585672 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01584474 0,05577624 ! neuron adhesion GO:0007158 14 7 0,000 0,01584474 0,05569598 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01584474 0,05561596 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01584474 0,05553617 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01584474 0,0554566 ! mRNA stabilization GO:0048255 18 7 0,000 0,01584474 0,05537726 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01584474 0,05529815 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01584474 0,05521927 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01584474 0,05514061 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01584474 0,05506217 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01584474 0,05498396 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01584474 0,05490597 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01584474 0,0548282 ! lipoprotein transport GO:0042953 14 7 0,000 0,01584474 0,05475065 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01584474 0,05467332 ! rhythmic behavior GO:0007622 17 7 0,000 0,01584474 0,0545962 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01584474 0,05451931 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01584474 0,05444263 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01584474 0,05436616 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01584474 0,05428991 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01584474 0,05421388 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01584474 0,05413805 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01584474 0,05406244 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01584474 0,05398704 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01584474 0,05391185 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01584474 0,05383687 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01584474 0,05376209 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01584474 0,05368753 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01584474 0,05361317 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01584474 0,05353901 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01584474 0,05346507 ! spinal cord patterning GO:0021511 14 7 0,000 0,01584474 0,05339132 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01584474 0,05331778 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01584474 0,05324444 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01584474 0,0531713 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01584474 0,05309836 ! adrenal gland development GO:0030325 17 7 0,000 0,01584474 0,05302563 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01584474 0,05295309 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01584474 0,05288075 ! ovulation GO:0030728 10 7 0,000 0,01584474 0,05280861 ! adenohypophysis development GO:0021984 11 7 0,000 0,01584474 0,05273666 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01584474 0,05266491 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01584474 0,05259335 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01584474 0,05252199 ! microtubule nucleation GO:0007020 21 7 0,000 0,01584474 0,05245082 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01584474 0,05237985 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01584474 0,05230906 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01584474 0,05223847 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01584474 0,05216807 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01584474 0,05209786 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01584474 0,05202783 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01584474 0,051958 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01584474 0,05188835 ! galactose metabolic process GO:0006012 13 7 0,000 0,01584474 0,05181889 ! vesicle fusion GO:0006906 20 7 0,000 0,01584474 0,05174961 ! response to dietary excess GO:0002021 8 7 0,000 0,01584474 0,05168052 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01584474 0,05161161 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01584474 0,05154289 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01584474 0,05147435 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01584474 0,05140599 ! organ growth GO:0035265 15 7 0,000 0,01584474 0,05133781 ! nucleoside transport GO:0015858 11 7 0,000 0,01584474 0,05126981 ! nucleoside salvage GO:0043174 11 7 0,000 0,01584474 0,05120199 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01584474 0,05113436 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01584474 0,0510669 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01584474 0,05099961 ! parturition GO:0007567 16 7 0,000 0,01584474 0,05093251 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01584474 0,05086558 ! rRNA modification GO:0000154 14 7 0,000 0,01584474 0,05079883 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01584474 0,05073225 ! spindle checkpoint GO:0031577 16 7 0,000 0,01584474 0,05066585 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01584474 0,05059962 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01584474 0,05053356 ! monocyte differentiation GO:0030224 16 7 0,000 0,01584474 0,05046768 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01584474 0,05040196 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01584474 0,05033642 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01584474 0,05027105 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01584474 0,05020585 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01584474 0,05014081 ! fibrinolysis GO:0042730 11 7 0,000 0,01584474 0,05007595 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01584474 0,05001125 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01584474 0,04994672 ! eating behavior GO:0042755 8 7 0,000 0,01584474 0,04988236 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01584474 0,04981816 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01584474 0,04975412 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01584474 0,04969025 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01584474 0,04962655 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01584474 0,04956301 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01584474 0,04949963 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01584474 0,04943641 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01584474 0,04937335 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01584474 0,04931046 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01584474 0,04924772 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01584474 0,04918514 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01584474 0,04912273 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01584474 0,04906047 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01584474 0,04899836 ! histone ubiquitination GO:0016574 9 7 0,000 0,01584474 0,04893642 ! regulation of meiosis GO:0040020 12 7 0,000 0,01584474 0,04887463 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01584474 0,048813 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01584474 0,04875152 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01584474 0,0486902 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01584474 0,04862903 ! transcription termination GO:0006353 14 7 0,000 0,01584474 0,04856801 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01584474 0,04850715 ! anaphase GO:0051322 18 7 0,000 0,01584474 0,04844644 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01584474 0,04838588 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01584474 0,04832548 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01584474 0,04826522 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01584474 0,04820512 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01584474 0,04814516 ! diuresis GO:0030146 12 7 0,000 0,01584474 0,04808535 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01584474 0,04802569 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01584474 0,04796618 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01584474 0,04790682 ! antibiotic transport GO:0042891 9 7 0,000 0,01584474 0,0478476 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01584474 0,04778853 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01584474 0,0477296 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01584474 0,04767082 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01584474 0,04761219 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01584474 0,04755369 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01584474 0,04749535 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01584474 0,04743714 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01584474 0,04737908 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01584474 0,04732116 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01584474 0,04726338 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01584474 0,04720574 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01584474 0,04714824 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01584474 0,04709089 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01584474 0,04703367 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01584474 0,04697659 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01584474 0,04691965 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01584474 0,04686284 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01584474 0,04680618 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01584474 0,04674965 ! muscle adaptation GO:0043500 13 7 0,000 0,01584474 0,04669325 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01584474 0,046637 ! retina homeostasis GO:0001895 12 7 0,000 0,01584474 0,04658088 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01584474 0,04652489 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01584474 0,04646904 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01584474 0,04641332 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01584474 0,04635773 ! T cell activation GO:0042110 189 84 1,000 0,01584632 0,04630688 ! response to nutrient GO:0007584 135 84 1,000 0,01584632 0,04625155 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,01620444 0,04724038 ! negative regulation of growth GO:0045926 168 85 1,000 0,01620444 0,04718408 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,01620444 0,0471279 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01620444 0,04707187 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,01729947 0,05019312 ! regulation of DNA binding GO:0051101 167 89 1,000 0,01767131 0,05121117 ! protein localization in nucleus GO:0034504 192 89 1,000 0,01767131 0,05115049 ! response to unfolded protein GO:0006986 139 90 1,000 0,01804654 0,0521748 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,01804654 0,05211313 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01808794 0,05217101 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01808794 0,05210949 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01808794 0,05204811 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01808794 0,05198687 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01808794 0,05192579 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01808794 0,05186484 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01808794 0,05180404 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01808794 0,05174338 ! male meiosis GO:0007140 9 8 0,000 0,01808794 0,05168286 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01808794 0,05162248 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01808794 0,05156224 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01808794 0,05150215 ! meiotic prophase I GO:0007128 14 8 0,000 0,01808794 0,05144219 ! response to zinc ion GO:0010043 12 8 0,000 0,01808794 0,05138238 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01808794 0,0513227 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01808794 0,05126316 ! oligopeptide transport GO:0006857 16 8 0,000 0,01808794 0,05120376 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01808794 0,05114449 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01808794 0,05108537 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01808794 0,05102638 ! signal peptide processing GO:0006465 12 8 0,000 0,01808794 0,05096752 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01808794 0,05090881 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01808794 0,05085022 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01808794 0,05079177 ! succinate metabolic process GO:0006105 17 8 0,000 0,01808794 0,05073346 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01808794 0,05067528 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01808794 0,05061723 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01808794 0,05055932 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01808794 0,05050154 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01808794 0,05044389 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01808794 0,05038637 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01808794 0,05032898 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01808794 0,05027172 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01808794 0,05021459 ! reflex GO:0060004 17 8 0,000 0,01808794 0,0501576 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01808794 0,05010073 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01808794 0,05004399 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01808794 0,04998738 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01808794 0,0499309 ! pigment granule organization GO:0048753 17 8 0,000 0,01808794 0,04987454 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01808794 0,04981831 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01808794 0,04976221 ! histidine catabolic process GO:0006548 10 8 0,000 0,01808794 0,04970624 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01808794 0,04965039 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01808794 0,04959466 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01808794 0,04953906 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01808794 0,04948359 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01808794 0,04942824 ! melanin metabolic process GO:0006582 17 8 0,000 0,01808794 0,04937301 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01808794 0,04931791 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01808794 0,04926292 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01808794 0,04920807 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01808794 0,04915333 ! macrophage activation GO:0042116 13 8 0,000 0,01808794 0,04909872 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01808794 0,04904422 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01808794 0,04898985 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01808794 0,0489356 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01808794 0,04888146 ! purine salvage GO:0043101 12 8 0,000 0,01808794 0,04882745 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01808794 0,04877356 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01808794 0,04871978 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01808794 0,04866613 ! osteoblast development GO:0002076 17 8 0,000 0,01808794 0,04861259 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01808794 0,04855917 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01808794 0,04850587 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01808794 0,04845268 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01808794 0,04839961 ! response to UV-B GO:0010224 17 8 0,000 0,01808794 0,04834666 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01808794 0,04829382 ! intermediate filament organization GO:0045109 12 8 0,000 0,01808794 0,0482411 ! cellular extravasation GO:0045123 13 8 0,000 0,01808794 0,04818849 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01808794 0,048136 ! response to antibiotic GO:0046677 11 8 0,000 0,01808794 0,04808362 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01808794 0,04803135 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01808794 0,0479792 ! DNA topological change GO:0006265 12 8 0,000 0,01808794 0,04792716 ! response to tropane GO:0014073 15 8 0,000 0,01808794 0,04787524 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01808794 0,04782342 ! melanosome transport GO:0032402 13 8 0,000 0,01808794 0,04777172 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,01808794 0,04772013 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01808794 0,04766866 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01808794 0,04761729 ! mast cell activation GO:0045576 14 8 0,000 0,01808794 0,04756603 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01808794 0,04751489 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01808794 0,04746385 ! gas homeostasis GO:0033483 14 8 0,000 0,01808794 0,04741292 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01808794 0,0473621 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01808794 0,0473114 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01808794 0,0472608 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01808794 0,0472103 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01808794 0,04715992 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01808794 0,04710964 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01808794 0,04705947 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01808794 0,04700941 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01808794 0,04695945 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01808794 0,0469096 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01808794 0,04685986 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01808794 0,04681022 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01808794 0,04676068 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01808794 0,04671125 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01808794 0,04666193 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01808794 0,0466127 ! hormone catabolic process GO:0042447 17 8 0,000 0,01808794 0,04656359 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01808794 0,04651457 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01808794 0,04646566 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01808794 0,04641685 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01808794 0,04636815 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01808794 0,04631954 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01808794 0,04627104 ! adult feeding behavior GO:0008343 10 8 0,000 0,01808794 0,04622264 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01808794 0,04617434 ! ATP catabolic process GO:0006200 11 8 0,000 0,01808794 0,04612614 ! blastocyst growth GO:0001832 19 8 0,000 0,01808794 0,04607804 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01808794 0,04603005 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01808794 0,04598215 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01808794 0,04593435 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01808794 0,04588665 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01808794 0,04583905 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01808794 0,04579155 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01808794 0,04574414 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01808794 0,04569684 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01808794 0,04564963 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01808794 0,04560252 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01808794 0,04555551 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01808794 0,04550859 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01808794 0,04546177 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01808794 0,04541505 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01808794 0,04536842 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01808794 0,04532189 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01808794 0,04527545 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01808794 0,04522911 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01808794 0,04518287 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01808794 0,04513671 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,01919239 0,04784389 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01919239 0,04779511 ! vitamin metabolic process GO:0006766 153 93 1,000 0,01919239 0,04774644 ! sterol metabolic process GO:0016125 166 94 1,000 0,019581 0,04866367 ! regulation of membrane potential GO:0042391 179 94 1,000 0,019581 0,04861421 ! regulation of defense response GO:0031347 171 95 1,000 0,01997292 0,04953689 ! axon extension GO:0048675 16 9 0,000 0,02032609 0,05036171 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02032609 0,05031068 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02032609 0,05025976 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02032609 0,05020894 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02032609 0,05015822 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02032609 0,05010761 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02032609 0,0500571 ! reproductive behavior GO:0019098 22 9 0,000 0,02032609 0,05000669 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02032609 0,04995638 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02032609 0,04990617 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02032609 0,04985607 ! UTP metabolic process GO:0046051 10 9 0,000 0,02032609 0,04980606 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02032609 0,04975615 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02032609 0,04970635 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02032609 0,04965664 ! artery development GO:0060840 25 9 0,000 0,02032609 0,04960704 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02032609 0,04955753 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02032609 0,04950812 ! equilibrioception GO:0050957 20 9 0,000 0,02032609 0,04945881 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02032609 0,04940959 ! chemosensory behavior GO:0007635 21 9 0,000 0,02032609 0,04936048 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02032609 0,04931146 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02032609 0,04926254 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02032609 0,04921372 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02032609 0,04916499 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02032609 0,04911636 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02032609 0,04906783 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02032609 0,04901939 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02032609 0,04897105 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02032609 0,0489228 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02032609 0,04887465 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02032609 0,04882659 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02032609 0,04877863 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02032609 0,04873076 ! T cell selection GO:0045058 27 9 0,000 0,02032609 0,04868298 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,02032609 0,0486353 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02032609 0,04858771 ! glycine catabolic process GO:0006546 15 9 0,000 0,02032609 0,04854022 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02032609 0,04849281 ! endosome organization GO:0007032 20 9 0,000 0,02032609 0,0484455 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02032609 0,04839829 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02032609 0,04835116 ! mannose metabolic process GO:0006013 13 9 0,000 0,02032609 0,04830413 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02032609 0,04825718 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02032609 0,04821033 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02032609 0,04816357 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02032609 0,0481169 ! receptor clustering GO:0043113 20 9 0,000 0,02032609 0,04807032 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02032609 0,04802383 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02032609 0,04797743 ! retinol metabolic process GO:0042572 20 9 0,000 0,02032609 0,04793112 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02032609 0,0478849 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02032609 0,04783877 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02032609 0,04779273 ! macrophage differentiation GO:0030225 15 9 0,000 0,02032609 0,04774677 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02032609 0,04770091 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02032609 0,04765513 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02032609 0,04760944 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02032609 0,04756383 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02032609 0,04751832 ! response to amine stimulus GO:0014075 13 9 0,000 0,02032609 0,04747289 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02032609 0,04742755 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02032609 0,04738229 ! erythrocyte development GO:0048821 17 9 0,000 0,02032609 0,04733712 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02032609 0,04729204 ! renal water homeostasis GO:0003091 15 9 0,000 0,02032609 0,04724704 ! postreplication repair GO:0006301 25 9 0,000 0,02032609 0,04720213 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02032609 0,04715731 ! icosanoid secretion GO:0032309 15 9 0,000 0,02032609 0,04711256 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02032609 0,04706791 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02032609 0,04702334 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02032609 0,04697885 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02032609 0,04693444 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02032609 0,04689013 ! sterol catabolic process GO:0016127 14 9 0,000 0,02032609 0,04684589 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02032609 0,04680174 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02032609 0,04675767 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02032609 0,04671368 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02032609 0,04666978 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02032609 0,04662596 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02032609 0,04658222 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02032609 0,04653856 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02032609 0,04649498 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02032609 0,04645149 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02032609 0,04640808 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02032609 0,04636475 ! purine base metabolic process GO:0006144 25 9 0,000 0,02032609 0,04632149 ! pigment granule transport GO:0051904 17 9 0,000 0,02032609 0,04627832 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02032609 0,04623524 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02032609 0,04619223 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02032609 0,0461493 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02032609 0,04610645 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02032609 0,04606368 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02032609 0,04602098 ! mitochondrion localization GO:0051646 18 9 0,000 0,02032609 0,04597837 ! sex differentiation GO:0007548 171 96 1,000 0,02036812 0,04603081 ! leukocyte differentiation GO:0002521 232 98 1,000 0,02116831 0,047795 ! mRNA transport GO:0051028 185 100 1,000 0,02198146 0,04958513 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0225592 0,05084145 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0225592 0,05079459 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0225592 0,05074782 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0225592 0,05070113 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0225592 0,05065453 ! associative learning GO:0008306 21 10 0,000 0,0225592 0,05060802 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0225592 0,05056159 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0225592 0,05051524 ! phosphate transport GO:0006817 24 10 0,000 0,0225592 0,05046899 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0225592 0,05042281 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0225592 0,05037672 ! CTP metabolic process GO:0046036 11 10 0,000 0,0225592 0,05033071 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0225592 0,05028479 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0225592 0,05023895 ! GTP metabolic process GO:0046039 11 10 0,000 0,0225592 0,0501932 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0225592 0,05014753 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0225592 0,05010194 ! social behavior GO:0035176 29 10 0,000 0,0225592 0,05005643 ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0225592 0,05001101 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0225592 0,04996567 ! androgen metabolic process GO:0008209 17 10 0,000 0,0225592 0,04992041 ! phospholipid efflux GO:0033700 19 10 0,000 0,0225592 0,04987523 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0225592 0,04983014 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0225592 0,04978512 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0225592 0,04974019 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0225592 0,04969534 ! lung alveolus development GO:0048286 26 10 0,000 0,0225592 0,04965057 ! pathogenesis GO:0009405 17 10 0,000 0,0225592 0,04960588 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0225592 0,04956127 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0225592 0,04951674 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0225592 0,04947229 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0225592 0,04942792 ! endoderm development GO:0007492 18 10 0,000 0,0225592 0,04938363 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0225592 0,04933942 ! arginine catabolic process GO:0006527 17 10 0,000 0,0225592 0,04929529 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0225592 0,04925123 ! proline metabolic process GO:0006560 13 10 0,000 0,0225592 0,04920726 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0225592 0,04916336 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0225592 0,04911955 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0225592 0,04907581 ! V(D)J recombination GO:0033151 34 10 0,000 0,0225592 0,04903215 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0225592 0,04898856 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0225592 0,04894505 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0225592 0,04890163 ! B cell proliferation GO:0042100 19 10 0,000 0,0225592 0,04885827 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0225592 0,048815 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0225592 0,0487718 ! multicellular organism growth GO:0035264 19 10 0,000 0,0225592 0,04872868 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0225592 0,04868563 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0225592 0,04864266 ! ruffle organization GO:0031529 17 10 0,000 0,0225592 0,04859976 ! epithelial cell development GO:0002064 21 10 0,000 0,0225592 0,04855694 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0225592 0,0485142 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0225592 0,04847153 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0225592 0,04842894 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0225592 0,04838642 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0225592 0,04834398 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0225592 0,04830161 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,0225592 0,04825931 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0225592 0,04821709 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0225592 0,04817494 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0225592 0,04813287 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0225592 0,04809087 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0225592 0,04804894 ! segment specification GO:0007379 15 10 0,000 0,0225592 0,04800708 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0225592 0,0479653 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0225592 0,04792359 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0225592 0,04788196 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0225592 0,04784039 ! response to dsRNA GO:0043331 23 10 0,000 0,0225592 0,0477989 ! DNA ligation GO:0006266 18 10 0,000 0,0225592 0,04775748 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0225592 0,04771613 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0225592 0,04767485 ! melanosome localization GO:0032400 16 10 0,000 0,0225592 0,04763365 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0225592 0,04759251 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0225592 0,04755145 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0225592 0,04751046 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0225592 0,04746954 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0225592 0,04742868 ! induction of an organ GO:0001759 17 10 0,000 0,0225592 0,0473879 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0225592 0,04734719 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0225592 0,04730655 ! protein sumoylation GO:0016925 17 10 0,000 0,0225592 0,04726598 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0225592 0,04722548 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0225592 0,04718504 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0225592 0,04714468 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0225592 0,04710439 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0225592 0,04706416 ! salivary gland development GO:0007431 28 10 0,000 0,0225592 0,047024 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0225592 0,04698391 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0225592 0,04694389 ! midbrain development GO:0030901 14 10 0,000 0,0225592 0,04690394 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0225592 0,04686406 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0225592 0,04682424 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0225592 0,04678449 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0225592 0,04674481 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0225592 0,0467052 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0225592 0,04666565 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0225592 0,04662617 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0225592 0,04658676 ! detection of calcium ion GO:0005513 24 10 0,000 0,0225592 0,04654741 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0225592 0,04650813 ! blastocyst formation GO:0001825 18 10 0,000 0,0225592 0,04646891 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0225592 0,04642977 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0225592 0,04639068 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0225592 0,04635167 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0225592 0,04631272 ! response to nicotine GO:0035094 20 10 0,000 0,0225592 0,04627383 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0225592 0,04623501 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0225592 0,04619625 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02478729 0,05071636 ! respiratory burst GO:0045730 17 11 0,000 0,02478729 0,05067392 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02478729 0,05063155 ! neuron fate specification GO:0048665 18 11 0,000 0,02478729 0,05058926 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02478729 0,05054703 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02478729 0,05050487 ! thyroid gland development GO:0030878 26 11 0,000 0,02478729 0,05046278 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02478729 0,05042077 ! synapsis GO:0007129 14 11 0,000 0,02478729 0,05037882 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02478729 0,05033694 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02478729 0,05029513 ! response to pain GO:0048265 27 11 0,000 0,02478729 0,05025339 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02478729 0,05021172 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02478729 0,05017012 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02478729 0,05012859 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02478729 0,05008713 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02478729 0,05004573 ! bone resorption GO:0045453 16 11 0,000 0,02478729 0,05000441 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02478729 0,04996315 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02478729 0,04992196 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02478729 0,04988084 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02478729 0,04983979 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02478729 0,0497988 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02478729 0,04975788 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02478729 0,04971703 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02478729 0,04967624 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02478729 0,04963552 ! UV protection GO:0009650 20 11 0,000 0,02478729 0,04959487 ! adult heart development GO:0007512 16 11 0,000 0,02478729 0,04955429 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02478729 0,04951377 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02478729 0,04947332 ! macroautophagy GO:0016236 19 11 0,000 0,02478729 0,04943293 ! temperature homeostasis GO:0001659 18 11 0,000 0,02478729 0,04939261 ! behavioral fear response GO:0001662 27 11 0,000 0,02478729 0,04935235 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02478729 0,04931217 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02478729 0,04927204 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02478729 0,04923198 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02478729 0,04919199 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02478729 0,04915206 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02478729 0,0491122 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02478729 0,0490724 ! regulation of organ growth GO:0046620 14 11 0,000 0,02478729 0,04903266 ! pigment granule localization GO:0051875 20 11 0,000 0,02478729 0,04899299 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02478729 0,04895339 ! vasoconstriction GO:0042310 20 11 0,000 0,02478729 0,04891384 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02478729 0,04887437 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02478729 0,04883495 ! embryonic axis specification GO:0000578 19 11 0,000 0,02478729 0,0487956 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02478729 0,04875631 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02478729 0,04871709 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02478729 0,04867793 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02478729 0,04863883 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02478729 0,04859979 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02478729 0,04856082 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02478729 0,04852191 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02478729 0,04848306 ! prophase GO:0051324 17 11 0,000 0,02478729 0,04844427 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02478729 0,04840555 ! nucleosome positioning GO:0016584 15 11 0,000 0,02478729 0,04836688 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02478729 0,04832828 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02478729 0,04828974 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02478729 0,04825127 ! apical protein localization GO:0045176 18 11 0,000 0,02478729 0,04821285 ! acid secretion GO:0046717 20 11 0,000 0,02478729 0,04817449 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02478729 0,0481362 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02478729 0,04809797 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02478729 0,04805979 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02478729 0,04802168 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02478729 0,04798363 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02478729 0,04794564 ! cholesterol efflux GO:0033344 21 11 0,000 0,02478729 0,0479077 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02478729 0,04786983 ! oocyte development GO:0048599 20 11 0,000 0,02478729 0,04783202 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02478729 0,04779427 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02478729 0,04775658 ! embryonic gut development GO:0048566 19 11 0,000 0,02478729 0,04771894 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02478729 0,04768137 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02478729 0,04764385 ! activation of innate immune response GO:0002218 16 11 0,000 0,02478729 0,0476064 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02478729 0,047569 ! lysogeny GO:0030069 22 11 0,000 0,02478729 0,04753166 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02478729 0,04749438 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02478729 0,04745716 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02478729 0,04742 ! nucleus localization GO:0051647 22 11 0,000 0,02478729 0,04738289 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02701035 0,0515921 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02701035 0,05155179 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02701035 0,05151155 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02701035 0,05147137 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02701035 0,05143125 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02701035 0,05139119 ! protein complex disassembly GO:0043241 28 12 0,000 0,02701035 0,0513512 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02701035 0,05131127 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02701035 0,0512714 ! hippocampus development GO:0021766 29 12 0,000 0,02701035 0,05123159 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02701035 0,05119185 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02701035 0,05115216 ! T cell proliferation GO:0042098 32 12 0,000 0,02701035 0,05111254 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02701035 0,05107298 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02701035 0,05103348 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02701035 0,05099404 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02701035 0,05095466 ! drug transport GO:0015893 16 12 0,000 0,02701035 0,05091535 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02701035 0,05087609 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02701035 0,0508369 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02701035 0,05079776 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02701035 0,05075869 ! focal adhesion formation GO:0048041 37 12 0,000 0,02701035 0,05071967 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02701035 0,05068071 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02701035 0,05064182 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02701035 0,05060298 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02701035 0,05056421 ! lipid digestion GO:0044241 21 12 0,000 0,02701035 0,05052549 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02701035 0,05048683 ! entry into host cell GO:0030260 34 12 0,000 0,02701035 0,05044823 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02701035 0,0504097 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02701035 0,05037121 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02701035 0,05033279 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02701035 0,05029443 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02701035 0,05025612 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02701035 0,05021788 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02701035 0,05017969 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02701035 0,05014156 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02701035 0,05010349 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02701035 0,05006547 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02701035 0,05002751 ! cranial nerve development GO:0021545 23 12 0,000 0,02701035 0,04998961 ! fucose catabolic process GO:0019317 25 12 0,000 0,02701035 0,04995177 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02701035 0,04991399 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02701035 0,04987626 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02701035 0,04983859 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02701035 0,04980097 ! zymogen activation GO:0031638 18 12 0,000 0,02701035 0,04976342 ! T cell homeostasis GO:0043029 28 12 0,000 0,02701035 0,04972592 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02701035 0,04968847 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02701035 0,04965108 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02701035 0,04961375 ! oocyte differentiation GO:0009994 21 12 0,000 0,02701035 0,04957648 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02701035 0,04953926 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02701035 0,04950209 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02701035 0,04946499 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02701035 0,04942793 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02701035 0,04939094 ! defense response to fungus GO:0050832 15 12 0,000 0,02701035 0,04935399 ! developmental induction GO:0031128 22 12 0,000 0,02701035 0,04931711 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02701035 0,04928028 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02701035 0,0492435 ! response to cold GO:0009409 17 12 0,000 0,02701035 0,04920678 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02701035 0,04917011 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02701035 0,0491335 ! localization within membrane GO:0051668 26 12 0,000 0,02701035 0,04909694 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02922841 0,05308923 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02922841 0,05304979 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02922841 0,0530104 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02922841 0,05297108 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02922841 0,05293181 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02922841 0,0528926 ! peroxisomal transport GO:0043574 28 13 0,000 0,02922841 0,05285345 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02922841 0,05281436 ! cartilage condensation GO:0001502 22 13 0,000 0,02922841 0,05277533 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02922841 0,05273635 ! organelle fusion GO:0048284 36 13 0,000 0,02922841 0,05269743 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02922841 0,05265857 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02922841 0,05261976 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02922841 0,05258101 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02922841 0,05254232 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02922841 0,05250369 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02922841 0,05246511 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02922841 0,05242659 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02922841 0,05238813 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02922841 0,05234972 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02922841 0,05231137 ! methionine metabolic process GO:0006555 31 13 0,000 0,02922841 0,05227307 ! plasma membrane organization GO:0007009 27 13 0,000 0,02922841 0,05223483 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02922841 0,05219665 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02922841 0,05215852 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02922841 0,05212045 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02922841 0,05208243 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,02922841 0,05204447 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02922841 0,05200657 ! exocrine system development GO:0035272 34 13 0,000 0,02922841 0,05196872 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02922841 0,05193092 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02922841 0,05189318 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02922841 0,05185549 ! L-glutamate transport GO:0015813 30 13 0,000 0,02922841 0,05181786 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02922841 0,05178029 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02922841 0,05174276 ! protein homotetramerization GO:0051289 24 13 0,000 0,02922841 0,0517053 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02922841 0,05166788 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02922841 0,05163052 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02922841 0,05159322 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02922841 0,05155597 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02922841 0,05151877 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02922841 0,05148163 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,02922841 0,05144454 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02922841 0,0514075 ! histone methylation GO:0016571 29 13 0,000 0,02922841 0,05137051 ! chromatin silencing GO:0006342 29 13 0,000 0,02922841 0,05133358 ! gland morphogenesis GO:0022612 31 13 0,000 0,02922841 0,05129671 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02922841 0,05125988 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02922841 0,05122311 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02922841 0,05118639 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02922841 0,05114972 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02922841 0,05111311 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02922841 0,05107655 ! spleen development GO:0048536 24 13 0,000 0,02922841 0,05104004 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02922841 0,05100358 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02922841 0,05096718 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02922841 0,05093082 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02922841 0,05089452 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02922841 0,05085827 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02922841 0,05082207 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02922841 0,05078593 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02922841 0,05074983 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02922841 0,05071379 ! insulin secretion GO:0030073 24 13 0,000 0,02922841 0,0506778 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02922841 0,05064185 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02922841 0,05060596 ! acrosome reaction GO:0007340 19 13 0,000 0,02922841 0,05057012 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02922841 0,05053433 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02922841 0,0504986 ! rRNA transcription GO:0009303 28 14 0,000 0,03144148 0,05428377 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03144148 0,05424544 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03144148 0,05420716 ! water transport GO:0006833 21 14 0,000 0,03144148 0,05416893 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03144148 0,05413075 ! non-recombinational repair GO:0000726 29 14 0,000 0,03144148 0,05409263 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03144148 0,05405457 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03144148 0,05401655 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03144148 0,05397859 ! lipid localization GO:0010876 32 14 0,000 0,03144148 0,05394069 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03144148 0,05390283 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03144148 0,05386503 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03144148 0,05382729 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03144148 0,05378959 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03144148 0,05375195 ! arginine metabolic process GO:0006525 21 14 0,000 0,03144148 0,05371436 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03144148 0,05367683 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03144148 0,05363934 ! regulation of heart rate GO:0002027 25 14 0,000 0,03144148 0,05360191 ! fear response GO:0042596 34 14 0,000 0,03144148 0,05356453 ! organic alcohol transport GO:0015850 29 14 0,000 0,03144148 0,0535272 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03144148 0,05348993 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03144148 0,05345271 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03144148 0,05341553 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03144148 0,05337841 ! bone mineralization GO:0030282 18 14 0,000 0,03144148 0,05334135 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03144148 0,05330433 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03144148 0,05326736 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03144148 0,05323045 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03144148 0,05319359 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03144148 0,05315677 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03144148 0,05312001 ! ribosome assembly GO:0042255 18 14 0,000 0,03144148 0,0530833 ! cerebellum development GO:0021549 23 14 0,000 0,03144148 0,05304664 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03144148 0,05301003 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03144148 0,05297347 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03144148 0,05293697 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03144148 0,05290051 ! NADP metabolic process GO:0006739 24 14 0,000 0,03144148 0,0528641 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03144148 0,05282774 ! oxygen transport GO:0015671 22 14 0,000 0,03144148 0,05279144 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03144148 0,05275518 ! male genitalia development GO:0030539 26 14 0,000 0,03144148 0,05271897 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03144148 0,05268281 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03144148 0,0526467 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03144148 0,05261064 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03364957 0,05626686 ! lactation GO:0007595 30 15 0,000 0,03364957 0,05622838 ! reproductive cellular process GO:0048610 22 15 0,000 0,03364957 0,05618994 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03364957 0,05615156 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03364957 0,05611323 ! superoxide anion generation GO:0042554 22 15 0,000 0,03364957 0,05607496 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03364957 0,05603673 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03364957 0,05599856 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03364957 0,05596044 ! copper ion transport GO:0006825 22 15 0,000 0,03364957 0,05592237 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03364957 0,05588436 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03364957 0,05584639 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03364957 0,05580848 ! sulfate transport GO:0008272 27 15 0,000 0,03364957 0,05577062 ! response to cAMP GO:0051591 25 15 0,000 0,03364957 0,05573281 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03364957 0,05569505 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03364957 0,05565734 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03364957 0,05561968 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03364957 0,05558208 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03364957 0,05554452 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03364957 0,05550701 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03364957 0,05546956 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03364957 0,05543216 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03364957 0,0553948 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03364957 0,0553575 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03364957 0,05532025 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03364957 0,05528305 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03364957 0,05524589 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03364957 0,05520879 ! histone deacetylation GO:0016575 24 15 0,000 0,03364957 0,05517174 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03364957 0,05513473 ! water homeostasis GO:0030104 28 15 0,000 0,03364957 0,05509778 ! cofactor transport GO:0051181 30 15 0,000 0,03364957 0,05506088 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03364957 0,05502402 ! muscle maintenance GO:0046716 26 15 0,000 0,03364957 0,05498722 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03364957 0,05495046 ! intestinal absorption GO:0050892 31 15 0,000 0,03364957 0,05491375 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03364957 0,0548771 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03364957 0,05484049 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03364957 0,05480393 ! cell killing GO:0001906 32 15 0,000 0,03364957 0,05476741 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03364957 0,05473095 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03364957 0,05469454 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03364957 0,05465817 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03364957 0,05462185 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03364957 0,05458558 ! actin filament polymerization GO:0030041 27 15 0,000 0,03364957 0,05454936 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03364957 0,05451319 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03585268 0,0580438 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03585268 0,05800536 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03585268 0,05796697 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03585268 0,05792863 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03585268 0,05789035 ! bone remodeling GO:0046849 28 16 0,000 0,03585268 0,05785211 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03585268 0,05781392 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03585268 0,05777579 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03585268 0,0577377 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03585268 0,05769967 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03585268 0,05766168 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03585268 0,05762375 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03585268 0,05758586 ! startle response GO:0001964 28 16 0,000 0,03585268 0,05754802 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03585268 0,05751024 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03585268 0,0574725 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03585268 0,05743482 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03585268 0,05739718 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03585268 0,05735959 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03585268 0,05732205 ! pituitary gland development GO:0021983 30 16 0,000 0,03585268 0,05728456 ! response to osmotic stress GO:0006970 27 16 0,000 0,03585268 0,05724712 ! lysosomal transport GO:0007041 31 16 0,000 0,03585268 0,05720973 ! fructose metabolic process GO:0006000 25 16 0,000 0,03585268 0,05717238 ! L-amino acid transport GO:0015807 33 16 0,000 0,03585268 0,05713509 ! stem cell development GO:0048864 46 16 0,000 0,03585268 0,05709784 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03585268 0,05706065 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03585268 0,0570235 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03585268 0,0569864 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03585268 0,05694935 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03585268 0,05691234 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03585268 0,05687539 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03585268 0,05683848 ! DNA replication initiation GO:0006270 28 16 0,000 0,03585268 0,05680162 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03585268 0,0567648 ! tissue regeneration GO:0042246 27 16 0,000 0,03585268 0,05672804 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03585268 0,05669132 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03585268 0,05665465 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03585268 0,05661803 ! biomineral formation GO:0031214 22 16 0,000 0,03585268 0,05658146 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03585268 0,05654493 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03585268 0,05650845 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03585268 0,05647201 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03585268 0,05643563 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03585268 0,05639929 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03585268 0,05636299 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03585268 0,05632675 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03585268 0,05629055 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,03585268 0,05625439 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03805083 0,05966507 ! metencephalon development GO:0022037 32 17 0,000 0,03805083 0,0596268 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03805083 0,05958858 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03805083 0,0595504 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03805083 0,05951228 ! signal complex assembly GO:0007172 47 17 0,000 0,03805083 0,0594742 ! filopodium assembly GO:0046847 42 17 0,000 0,03805083 0,05943617 ! endothelial cell migration GO:0043542 31 17 0,000 0,03805083 0,0593982 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03805083 0,05936027 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03805083 0,05932239 ! glial cell development GO:0021782 28 17 0,000 0,03805083 0,05928455 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03805083 0,05924677 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03805083 0,05920903 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03805083 0,05917134 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03805083 0,0591337 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03805083 0,05909611 ! myoblast differentiation GO:0045445 50 17 0,000 0,03805083 0,05905856 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03805083 0,05902107 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03805083 0,05898362 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03805083 0,05894621 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03805083 0,05890886 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03805083 0,05887155 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03805083 0,05883429 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03805083 0,05879708 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03805083 0,05875991 ! regulation of protein binding GO:0043393 33 17 0,000 0,03805083 0,05872279 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03805083 0,05868572 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03805083 0,05864869 ! genitalia development GO:0048806 32 17 0,000 0,03805083 0,05861171 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03805083 0,05857478 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03805083 0,0585379 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03805083 0,05850106 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03805083 0,05846426 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03805083 0,05842752 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03805083 0,05839082 ! steroid catabolic process GO:0006706 34 17 0,000 0,03805083 0,05835416 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03805083 0,05831755 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03805083 0,05828099 ! gas transport GO:0015669 26 17 0,000 0,03805083 0,05824447 ! organic cation transport GO:0015695 32 17 0,000 0,03805083 0,058208 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03805083 0,05817158 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03805083 0,0581352 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03805083 0,05809886 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04024403 0,06140923 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04024403 0,06137089 ! limbic system development GO:0021761 40 18 0,000 0,04024403 0,06133261 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04024403 0,06129437 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04024403 0,06125618 ! adult walking behavior GO:0007628 36 18 0,000 0,04024403 0,06121804 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04024403 0,06117994 ! heart looping GO:0001947 34 18 0,000 0,04024403 0,0611419 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04024403 0,0611039 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04024403 0,06106594 ! centrosome cycle GO:0007098 26 18 0,000 0,04024403 0,06102804 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04024403 0,06099018 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04024403 0,06095237 ! glycine metabolic process GO:0006544 30 18 0,000 0,04024403 0,0609146 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04024403 0,06087689 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04024403 0,06083921 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04024403 0,06080159 ! DNA integration GO:0015074 32 18 0,000 0,04024403 0,06076401 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04024403 0,06072648 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04024403 0,06068899 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04024403 0,06065155 ! neural crest cell migration GO:0001755 41 18 0,000 0,04024403 0,06061416 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04024403 0,06057681 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04024403 0,06053951 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04024403 0,06050226 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04024403 0,06046505 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04024403 0,06042789 ! detection of bacterium GO:0016045 22 18 0,000 0,04024403 0,06039077 ! nerve development GO:0021675 34 18 0,000 0,04024403 0,0603537 ! defense response to virus GO:0051607 43 18 0,000 0,04024403 0,06031667 ! microspike assembly GO:0030035 46 18 0,000 0,04024403 0,06027969 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04024403 0,06024275 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04024403 0,06020586 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04243229 0,0634407 ! positive regulation of translation GO:0045727 31 19 0,000 0,04243229 0,06340189 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04243229 0,06336314 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04243229 0,06332443 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04243229 0,06328577 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04243229 0,06324716 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04243229 0,0632086 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04243229 0,06317008 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04243229 0,06313161 ! inositol metabolic process GO:0006020 33 19 0,000 0,04243229 0,06309318 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04243229 0,0630548 ! memory GO:0007613 34 19 0,000 0,04243229 0,06301647 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04243229 0,06297819 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04243229 0,06293995 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04243229 0,06290176 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04243229 0,06286361 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04243229 0,06282551 ! cerebral cortex development GO:0021987 40 19 0,000 0,04243229 0,06278746 ! pigmentation during development GO:0048066 42 19 0,000 0,04243229 0,06274945 ! heme metabolic process GO:0042168 40 19 0,000 0,04243229 0,06271149 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04243229 0,06267358 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04243229 0,06263571 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04243229 0,06259788 ! response to fungus GO:0009620 26 19 0,000 0,04243229 0,06256011 ! peptide cross-linking GO:0018149 39 19 0,000 0,04243229 0,06252237 ! protein export from nucleus GO:0006611 40 19 0,000 0,04243229 0,06248469 ! heart process GO:0003015 32 19 0,000 0,04243229 0,06244705 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04243229 0,06240945 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04243229 0,0623719 ! visual learning GO:0008542 38 19 0,000 0,04243229 0,06233439 ! cellular pigmentation GO:0033059 37 19 0,000 0,04243229 0,06229693 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04243229 0,06225952 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04243229 0,06222215 ! vitamin transport GO:0051180 31 19 0,000 0,04243229 0,06218482 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04243229 0,06214754 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04243229 0,0621103 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04243229 0,06207311 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04243229 0,06203596 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04243229 0,06199886 ! cilium assembly GO:0042384 38 19 0,000 0,04243229 0,0619618 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04243229 0,06192479 ! protein secretion GO:0009306 45 20 0,000 0,04461563 0,06507223 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04461563 0,0650334 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04461563 0,06499462 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04461563 0,06495589 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04461563 0,0649172 ! skin development GO:0043588 42 20 0,000 0,04461563 0,06487856 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,04461563 0,06483997 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04461563 0,06480142 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04461563 0,06476291 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04461563 0,06472446 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04461563 0,06468604 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04461563 0,06464768 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04461563 0,06460936 ! response to alkaloid GO:0043279 38 20 0,000 0,04461563 0,06457108 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04461563 0,06453285 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04461563 0,06449467 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04461563 0,06445653 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04461563 0,06441843 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04461563 0,06438038 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04461563 0,06434238 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04461563 0,06430442 ! body fluid secretion GO:0007589 33 20 0,000 0,04461563 0,0642665 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04461563 0,06422863 ! peptide secretion GO:0002790 38 20 0,000 0,04461563 0,0641908 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04461563 0,06415302 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04461563 0,06411528 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04461563 0,06407759 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04461563 0,06403994 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04461563 0,06400234 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04461563 0,06396478 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04461563 0,06392726 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04461563 0,06388979 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04461563 0,06385236 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04461563 0,06381498 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04461563 0,06377764 ! regulation of glucose import GO:0046324 30 20 0,000 0,04461563 0,06374034 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04461563 0,06370309 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04461563 0,06366588 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04461563 0,06362871 ! negative regulation of translation GO:0017148 32 20 0,000 0,04461563 0,06359159 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04461563 0,06355451 ! regulation of cell killing GO:0031341 46 21 0,000 0,04679405 0,0666188 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04679405 0,06658 ! hormone secretion GO:0046879 39 21 0,000 0,04679405 0,06654125 ! lipid phosphorylation GO:0046834 43 21 0,000 0,04679405 0,06650254 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04679405 0,06646387 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04679405 0,06642525 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04679405 0,06638668 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04679405 0,06634815 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04679405 0,06630966 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04679405 0,06627122 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04679405 0,06623283 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04679405 0,06619448 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04679405 0,06615617 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04679405 0,06611791 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04679405 0,06607969 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04679405 0,06604151 ! sensory perception of pain GO:0019233 33 21 0,000 0,04679405 0,06600338 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04679405 0,0659653 ! diencephalon development GO:0021536 36 21 0,000 0,04679405 0,06592726 ! collagen fibril organization GO:0030199 62 21 0,000 0,04679405 0,06588926 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04679405 0,0658513 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04679405 0,06581339 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04679405 0,06577552 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04679405 0,0657377 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04679405 0,06569992 ! collagen catabolic process GO:0030574 29 21 0,000 0,04679405 0,06566218 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04679405 0,06562449 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04679405 0,06558684 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04679405 0,06554923 ! actin filament-based movement GO:0030048 47 21 0,000 0,04679405 0,06551167 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04896756 0,06851532 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04896756 0,0684761 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04896756 0,06843693 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04896756 0,0683978 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04896756 0,06835871 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04896756 0,06831968 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04896756 0,06828068 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04896756 0,06824173 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,04896756 0,06820282 ! vacuolar transport GO:0007034 41 22 0,000 0,04896756 0,06816396 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04896756 0,06812514 ! fucose metabolic process GO:0006004 44 22 0,000 0,04896756 0,06808637 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04896756 0,06804764 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04896756 0,06800895 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04896756 0,06797031 ! ureteric bud development GO:0001657 50 22 0,000 0,04896756 0,06793172 ! stem cell differentiation GO:0048863 57 22 0,000 0,04896756 0,06789316 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04896756 0,06785465 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04896756 0,06781619 ! cytolysis GO:0019835 27 22 0,000 0,04896756 0,06777776 ! renal system process GO:0003014 42 22 0,000 0,04896756 0,06773938 ! vasodilation GO:0042311 40 22 0,000 0,04896756 0,06770105 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04896756 0,06766276 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04896756 0,06762451 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04896756 0,0675863 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04896756 0,06754814 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04896756 0,06751002 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04896756 0,06747194 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04896756 0,06743391 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04896756 0,06739592 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04896756 0,06735797 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04896756 0,06732006 ! sarcomere organization GO:0045214 32 22 0,000 0,04896756 0,0672822 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,04896756 0,06724438 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04896756 0,0672066 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04896756 0,06716887 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04896756 0,06713117 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04896756 0,06709352 ! gut development GO:0048565 44 22 0,000 0,04896756 0,06705591 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04896756 0,06701835 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04896756 0,06698082 ! protein stabilization GO:0050821 41 22 0,000 0,04896756 0,06694334 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05113618 0,06986895 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05113618 0,0698299 ! gluconeogenesis GO:0006094 38 23 0,000 0,05113618 0,06979088 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05113618 0,06975192 ! viral genome replication GO:0019079 44 23 0,000 0,05113618 0,06971299 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05113618 0,06967411 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05113618 0,06963528 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,05113618 0,06959648 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05113618 0,06955773 ! regeneration GO:0031099 42 23 0,000 0,05113618 0,06951902 ! axis specification GO:0009798 43 23 0,000 0,05113618 0,06948036 ! visual behavior GO:0007632 46 23 0,000 0,05113618 0,06944174 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05113618 0,06940316 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05113618 0,06936462 ! response to ethanol GO:0045471 47 23 0,000 0,05113618 0,06932613 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05113618 0,06928768 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05113618 0,06924927 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05113618 0,06921091 ! peroxisome organization GO:0007031 43 23 0,000 0,05113618 0,06917258 ! lysosome organization GO:0007040 47 23 0,000 0,05113618 0,0691343 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05113618 0,06909606 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05113618 0,06905787 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05113618 0,06901971 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05113618 0,0689816 ! DNA modification GO:0006304 36 23 0,000 0,05113618 0,06894353 ! fatty acid transport GO:0015908 47 23 0,000 0,05113618 0,06890551 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05113618 0,06886752 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05113618 0,06882958 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05113618 0,06879168 ! hormone transport GO:0009914 41 23 0,000 0,05113618 0,06875382 ! cell-cell recognition GO:0009988 28 23 0,000 0,05113618 0,068716 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05113618 0,06867822 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05113618 0,06864049 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05113618 0,06860279 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05329991 0,07146635 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05329991 0,07142714 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05329991 0,07138798 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05329991 0,07134887 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05329991 0,07130979 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05329991 0,07127076 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05329991 0,07123177 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05329991 0,07119283 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05329991 0,07115393 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05329991 0,07111506 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,05329991 0,07107625 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05329991 0,07103747 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05329991 0,07099874 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05329991 0,07096005 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05329991 0,0709214 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05329991 0,07088279 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05329991 0,07084422 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05329991 0,0708057 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05329991 0,07076722 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,05329991 0,07072878 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05329991 0,07069038 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05329991 0,07065203 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05329991 0,07061371 ! membrane depolarization GO:0051899 45 24 0,000 0,05329991 0,07057544 ! pallium development GO:0021543 56 24 0,000 0,05329991 0,07053721 ! oogenesis GO:0048477 44 24 0,000 0,05329991 0,07049902 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05329991 0,07046087 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05329991 0,07042276 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,05329991 0,07038469 ! platelet activation GO:0030168 41 24 0,000 0,05329991 0,07034667 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05329991 0,07030868 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05329991 0,07027074 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05329991 0,07023284 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05329991 0,07019498 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05329991 0,07015716 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05329991 0,07011938 ! regulation of amine transport GO:0051952 41 24 0,000 0,05329991 0,07008164 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,05545877 0,072881 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,05545877 0,07284182 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,05545877 0,07280268 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,05545877 0,07276358 ! leukocyte adhesion GO:0007159 55 25 0,000 0,05545877 0,07272452 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05545877 0,0726855 ! phototransduction GO:0007602 37 25 0,000 0,05545877 0,07264653 ! keratinization GO:0031424 37 25 0,000 0,05545877 0,0726076 ! vasculogenesis GO:0001570 49 25 0,000 0,05545877 0,07256871 ! vacuole organization GO:0007033 49 25 0,000 0,05545877 0,07252986 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05545877 0,07249105 ! receptor metabolic process GO:0043112 53 25 0,000 0,05545877 0,07245229 ! chromosome condensation GO:0030261 48 25 0,000 0,05545877 0,07241356 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05545877 0,07237488 ! regulation of behavior GO:0050795 48 25 0,000 0,05545877 0,07233624 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,05545877 0,07229764 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05545877 0,07225908 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,05545877 0,07222056 ! immunoglobulin production GO:0002377 62 25 0,000 0,05545877 0,07218209 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,05545877 0,07214365 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,05545877 0,07210526 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,05545877 0,0720669 ! liver development GO:0001889 55 25 0,000 0,05545877 0,07202859 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05761277 0,07478639 ! myelination GO:0042552 50 26 0,000 0,05761277 0,07474668 ! initiation of viral infection GO:0019059 60 26 0,000 0,05761277 0,074707 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05761277 0,07466737 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05761277 0,07462778 ! molting cycle process GO:0022404 52 26 0,000 0,05761277 0,07458823 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05761277 0,07454873 ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05761277 0,07450926 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05761277 0,07446984 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05761277 0,07443046 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05761277 0,07439112 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05761277 0,07435182 ! digestive system process GO:0022600 49 26 0,000 0,05761277 0,07431256 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05761277 0,07427335 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,05761277 0,07423417 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05761277 0,07419504 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05761277 0,07415595 ! neural crest cell development GO:0014032 59 26 0,000 0,05761277 0,0741169 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05761277 0,07407789 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05761277 0,07403892 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05761277 0,074 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05761277 0,07396111 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05761277 0,07392227 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05761277 0,07388346 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05761277 0,0738447 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05761277 0,07380598 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05761277 0,07376729 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05761277 0,07372865 ! blastocyst development GO:0001824 50 26 0,000 0,05761277 0,07369005 ! telomere organization GO:0032200 46 26 0,000 0,05761277 0,07365149 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05761277 0,07361297 ! neural tube closure GO:0001843 58 26 0,000 0,05761277 0,07357449 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05761277 0,07353605 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05761277 0,07349765 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05976192 0,07619956 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05976192 0,07615981 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05976192 0,0761201 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05976192 0,07608044 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05976192 0,07604081 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05976192 0,07600123 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05976192 0,07596168 ! iron ion transport GO:0006826 65 27 0,000 0,05976192 0,07592218 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05976192 0,07588272 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05976192 0,0758433 ! tube lumen formation GO:0035148 59 27 0,000 0,05976192 0,07580392 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05976192 0,07576459 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,05976192 0,07572529 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05976192 0,07568603 ! response to toxin GO:0009636 49 27 0,000 0,05976192 0,07564682 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05976192 0,07560764 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05976192 0,07556851 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05976192 0,07552941 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05976192 0,07549036 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05976192 0,07545135 ! neuron fate commitment GO:0048663 52 28 0,000 0,06190622 0,07811823 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,06190622 0,0780779 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,06190622 0,07803761 ! vesicle docking GO:0048278 55 28 0,000 0,06190622 0,07799737 ! circadian rhythm GO:0007623 56 28 0,000 0,06190622 0,07795716 ! dendrite development GO:0016358 67 28 0,000 0,06190622 0,077917 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,06190622 0,07787688 ! fat cell differentiation GO:0045444 57 28 0,000 0,06190622 0,0778368 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06190622 0,07779676 ! sperm motility GO:0030317 37 28 0,000 0,06190622 0,07775676 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,06190622 0,0777168 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,06190622 0,07767689 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06190622 0,07763701 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,06190622 0,07759718 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06190622 0,07755738 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06190622 0,07751763 ! glutathione metabolic process GO:0006749 42 28 0,000 0,06190622 0,07747792 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,06190622 0,07743825 ! lipid oxidation GO:0034440 48 28 0,000 0,06190622 0,07739862 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,06190622 0,07735903 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06190622 0,07731948 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,0640457 0,07995076 ! translational initiation GO:0006413 66 29 0,000 0,0640457 0,07990993 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,0640457 0,07986913 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,0640457 0,07982838 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,0640457 0,07978768 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,0640457 0,07974701 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,0640457 0,07970638 ! primary neural tube formation GO:0014020 61 29 0,000 0,0640457 0,0796658 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,0640457 0,07962526 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,0640457 0,07958476 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,0640457 0,0795443 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,0640457 0,07950388 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,0640457 0,0794635 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,0640457 0,07942316 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06618035 0,08202872 ! phenol metabolic process GO:0018958 56 30 0,000 0,06618035 0,08198712 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06618035 0,08194556 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06618035 0,08190405 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06618035 0,08186258 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06618035 0,08182115 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06618035 0,08177977 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06618035 0,08173842 ! acute-phase response GO:0006953 50 30 0,000 0,06618035 0,08169712 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06618035 0,08165586 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06618035 0,08161464 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,06618035 0,08157346 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06618035 0,08153232 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06618035 0,08149123 ! cell fate determination GO:0001709 64 30 0,000 0,06618035 0,08145018 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06618035 0,08140916 ! phospholipid transport GO:0015914 65 30 0,000 0,06618035 0,08136819 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06618035 0,08132726 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06618035 0,08128637 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06618035 0,08124553 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06618035 0,08120472 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06618035 0,08116395 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,06618035 0,08112323 ! regulation of coagulation GO:0050818 52 30 0,000 0,06618035 0,08108255 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0683102 0,08365003 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0683102 0,08360812 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0683102 0,08356626 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0683102 0,08352443 ! cell junction assembly GO:0034329 85 31 0,000 0,0683102 0,08348265 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0683102 0,08344091 ! peptide transport GO:0015833 60 31 0,000 0,0683102 0,08339921 ! iron ion homeostasis GO:0055072 60 31 0,000 0,0683102 0,08335755 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0683102 0,08331593 ! detection of light stimulus GO:0009583 44 31 0,000 0,0683102 0,08327436 ! natural killer cell activation GO:0030101 50 31 0,000 0,0683102 0,08323282 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0683102 0,08319133 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0683102 0,08314988 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,0683102 0,08310847 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0683102 0,08306711 ! eye morphogenesis GO:0048592 65 31 0,000 0,0683102 0,08302578 ! response to heat GO:0009408 54 31 0,000 0,0683102 0,08298449 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0683102 0,08294325 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07043525 0,08548103 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07043525 0,08543858 ! collagen metabolic process GO:0032963 49 32 0,000 0,07043525 0,08539618 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07043525 0,08535382 ! spindle organization GO:0007051 50 32 0,000 0,07043525 0,08531151 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07043525 0,08526923 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07043525 0,085227 ! metanephros development GO:0001656 81 32 0,000 0,07043525 0,08518481 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07043525 0,08514266 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,07043525 0,08510055 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07043525 0,08505848 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07043525 0,08501646 ! BMP signaling pathway GO:0030509 71 32 0,000 0,07043525 0,08497447 ! hindbrain development GO:0030902 65 32 0,000 0,07043525 0,08493253 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,07043525 0,08489063 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07043525 0,08484877 ! gene silencing GO:0016458 71 32 0,000 0,07043525 0,08480695 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07255551 0,0873168 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,07255551 0,08727381 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07255551 0,08723086 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07255551 0,08718795 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,07255551 0,08714509 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07255551 0,08710227 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,07255551 0,08705948 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07255551 0,08701674 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07255551 0,08697405 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,07255551 0,08693139 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07467099 0,08942218 ! glial cell differentiation GO:0010001 67 34 0,000 0,07467099 0,08937836 ! post-embryonic development GO:0009791 76 34 0,000 0,07467099 0,08933459 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07467099 0,08929087 ! cholesterol transport GO:0030301 62 34 0,000 0,07467099 0,08924718 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07467099 0,08920354 ! spliceosome assembly GO:0000245 75 34 0,000 0,07467099 0,08915994 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07467099 0,08911639 ! cell fate specification GO:0001708 56 34 0,000 0,07467099 0,08907287 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,07467099 0,0890294 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07467099 0,08898597 ! adult locomotory behavior GO:0008344 62 34 0,000 0,07467099 0,08894258 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,07678171 0,09141215 ! negative regulation of secretion GO:0051048 68 35 0,000 0,07678171 0,09136762 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,07678171 0,09132314 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,07678171 0,0912787 ! membrane docking GO:0022406 69 35 0,000 0,07678171 0,0912343 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,07678171 0,09118995 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,07678171 0,09114564 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,07678171 0,09110137 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,07678171 0,09105715 ! ceramide metabolic process GO:0006672 72 35 0,000 0,07678171 0,09101297 ! telencephalon development GO:0021537 81 35 0,000 0,07678171 0,09096883 ! sterol transport GO:0015918 63 35 0,000 0,07678171 0,09092473 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,07678171 0,09088068 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,07678171 0,09083667 ! placenta development GO:0001890 53 35 0,000 0,07678171 0,0907927 ! regulation of muscle development GO:0048634 82 36 0,000 0,07888768 0,09323783 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07888768 0,09319275 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07888768 0,0931477 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07888768 0,0931027 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07888768 0,09305775 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07888768 0,09301284 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07888768 0,09296797 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07888768 0,09292314 ! aerobic respiration GO:0009060 56 36 0,000 0,07888768 0,09287836 ! cytokine production GO:0001816 68 36 0,000 0,07888768 0,09283362 ! embryonic organ development GO:0048568 67 36 0,000 0,07888768 0,09278893 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07888768 0,09274427 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07888768 0,09269966 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,0809889 0,09512302 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,0809889 0,09507731 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0809889 0,09503164 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0809889 0,09498602 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0809889 0,09494044 ! odontogenesis GO:0042476 74 37 0,000 0,0809889 0,09489491 ! cell junction organization GO:0034330 96 37 0,000 0,0809889 0,09484941 ! tissue remodeling GO:0048771 78 37 0,000 0,0809889 0,09480397 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0809889 0,09475856 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0809889 0,0947132 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0809889 0,09466788 ! meiosis I GO:0007127 74 38 0,000 0,08308538 0,09707202 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,08308538 0,09702562 ! organic anion transport GO:0015711 82 38 0,000 0,08308538 0,09697926 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08308538 0,09693295 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08308538 0,09688668 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,08308538 0,09684045 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,08308538 0,09679427 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,08308538 0,09674814 ! regulation of protein stability GO:0031647 77 38 0,000 0,08308538 0,09670204 ! spermatid development GO:0007286 69 38 0,000 0,08308538 0,096656 ! glycogen metabolic process GO:0005977 63 38 0,000 0,08308538 0,09660999 ! pigment metabolic process GO:0042440 87 38 0,000 0,08308538 0,09656403 ! neural tube formation GO:0001841 79 38 0,000 0,08308538 0,09651811 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08517714 0,09890103 ! negative regulation of binding GO:0051100 71 39 0,000 0,08517714 0,09885404 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08517714 0,09880711 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08517714 0,09876021 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08517714 0,09871336 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08517714 0,09866655 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,08517714 0,09861979 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 0,000 0,08517714 0,09857308 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08726419 0,10094054 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,08726419 0,10089277 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08726419 0,10084504 ! learning GO:0007612 82 40 0,000 0,08726419 0,10079736 ! nucleus organization GO:0006997 73 40 0,000 0,08726419 0,10074973 ! lipid homeostasis GO:0055088 75 40 0,000 0,08726419 0,10070214 ! mismatch repair GO:0006298 58 40 0,000 0,08726419 0,10065459 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08726419 0,10060709 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,08726419 0,10055963 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08726419 0,10051222 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08934654 0,1028622 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08934654 0,10281375 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08934654 0,10276535 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08934654 0,10271699 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08934654 0,10266867 ! gliogenesis GO:0042063 91 41 0,000 0,08934654 0,1026204 ! feeding behavior GO:0007631 69 41 0,000 0,08934654 0,10257218 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08934654 0,102524 ! mesenchymal cell development GO:0014031 94 41 0,000 0,08934654 0,10247587 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08934654 0,10242778 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,08934654 0,10237973 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08934654 0,10233174 ! RNA modification GO:0009451 64 41 0,000 0,08934654 0,10228378 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,09142419 0,10461326 ! ear morphogenesis GO:0042471 64 42 0,000 0,09142419 0,10456428 ! organic ether metabolic process GO:0018904 59 42 0,000 0,09142419 0,10451535 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09142419 0,10446646 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,09142419 0,10441763 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,09142419 0,10436883 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,09142419 0,10432008 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,09142419 0,10427138 ! regulation of protein secretion GO:0050708 77 42 0,000 0,09142419 0,10422273 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,09142419 0,10417411 ! cytokinesis GO:0000910 84 42 0,000 0,09142419 0,10412555 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,09142419 0,10407703 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,09349716 0,10638732 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,09349716 0,10633779 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,09349716 0,10628831 ! regulation of tube size GO:0035150 76 43 0,000 0,09349716 0,10623887 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,09349716 0,10618948 ! glucose transport GO:0015758 66 43 0,000 0,09349716 0,10614014 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,09349716 0,10609084 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,09349716 0,10604158 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,09349716 0,10599238 ! ion transmembrane transport GO:0034220 79 43 0,000 0,09349716 0,10594321 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,09349716 0,1058941 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09556546 0,10818648 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09556546 0,10813637 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,09556546 0,10808631 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09556546 0,10803629 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,09556546 0,10798632 ! hexose transport GO:0008645 68 44 0,000 0,09556546 0,1079364 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,09556546 0,10788652 ! phagocytosis GO:0006909 105 44 0,000 0,09556546 0,10783669 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09556546 0,1077869 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,0976291 0,11006364 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,0976291 0,11001287 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,0976291 0,10996215 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,0976291 0,10991147 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,0976291 0,10986085 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,0976291 0,10981027 ! female gamete generation GO:0007292 71 45 0,000 0,0976291 0,10975973 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,0976291 0,10970925 ! polyol metabolic process GO:0019751 77 45 0,000 0,0976291 0,1096588 ! developmental growth GO:0048589 88 45 0,000 0,0976291 0,10960841 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09968809 0,11186863 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09968809 0,11181727 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,09968809 0,11176595 ! glycolysis GO:0006096 71 46 0,000 0,09968809 0,11171468 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,09968809 0,11166346 ! leukocyte migration GO:0050900 75 46 0,000 0,09968809 0,11161229 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,09968809 0,11156116 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09968809 0,11151008 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09968809 0,11145904 ! pigmentation GO:0043473 103 46 0,000 0,09968809 0,11140806 ! cell growth GO:0016049 90 46 0,000 0,09968809 0,11135711 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,09968809 0,11130622 ! neural tube development GO:0021915 91 47 0,000 0,10174244 0,1135481 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,10174244 0,11349625 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,10379216 0,11572992 ! positive regulation of defense response GO:0031349 88 48 0,000 0,10379216 0,11567712 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,10379216 0,11562437 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,10379216 0,11557167 ! cellular component disassembly GO:0022411 89 48 0,000 0,10379216 0,11551902 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,10379216 0,11546641 ! endosome transport GO:0016197 127 48 0,000 0,10379216 0,11541386 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,10379216 0,11536135 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,10379216 0,11530889 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,10379216 0,11525648 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,10379216 0,11520411 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,10379216 0,11515179 ! response to calcium ion GO:0051592 94 49 0,000 0,10583726 0,11736742 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10583726 0,11731417 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10583726 0,11726096 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,10583726 0,11720781 ! JNK cascade GO:0007254 106 49 0,000 0,10583726 0,1171547 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,10583726 0,11710164 ! protein homooligomerization GO:0051260 84 49 0,000 0,10583726 0,11704863 ! regulation of action potential GO:0001508 102 50 0,000 0,10787775 0,11925128 ! regulation of ion transport GO:0043269 86 50 0,000 0,10787775 0,11919735 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10787775 0,11914346 ! endocrine system development GO:0035270 109 50 0,000 0,10787775 0,11908962 ! regulation of ossification GO:0030278 123 50 0,000 0,10787775 0,11903583 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10787775 0,11898209 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10787775 0,1189284 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10787775 0,11887476 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10787775 0,11882116 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10787775 0,11876762 ! viral infectious cycle GO:0019058 104 51 0,000 0,10991364 0,12095451 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,10991364 0,12090005 ! peptide metabolic process GO:0006518 80 51 0,000 0,10991364 0,12084564 ! response to temperature stimulus GO:0009266 84 51 0,000 0,10991364 0,12079128 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,10991364 0,12073697 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,10991364 0,12068271 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,11194494 0,12285781 ! Notch signaling pathway GO:0007219 111 52 0,000 0,11194494 0,12280264 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,11194494 0,12274753 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,11194494 0,12269246 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,11194494 0,12263744 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,11194494 0,12258247 ! excretion GO:0007588 87 52 0,000 0,11194494 0,12252755 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,11194494 0,12247268 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,11194494 0,12241786 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,11194494 0,12236308 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,11194494 0,12230836 ! amino acid activation GO:0043038 98 52 0,000 0,11194494 0,12225368 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,11397166 0,12441143 ! inner ear development GO:0048839 89 53 0,000 0,11397166 0,12435586 ! chromatin remodeling GO:0006338 122 53 0,000 0,11397166 0,12430035 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,11397166 0,12424488 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,11397166 0,12418946 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,11397166 0,12413409 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,11397166 0,12407878 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11599382 0,12622401 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11599382 0,12616781 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11599382 0,12611166 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,11599382 0,12605556 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,11599382 0,12599951 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,11599382 0,12594351 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,11599382 0,12588756 ! membrane fusion GO:0006944 122 54 0,000 0,11599382 0,12583166 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11599382 0,12577581 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11599382 0,12572001 ! regulation of cell shape GO:0008360 142 54 0,000 0,11599382 0,12566426 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,11599382 0,12560855 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,11801142 0,12773677 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,11801142 0,1276802 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,11801142 0,12762368 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,11801142 0,12756721 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,11801142 0,12751079 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,11801142 0,12745442 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12002446 0,12957126 ! glucose catabolic process GO:0006007 88 56 0,000 0,12002446 0,12951403 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,12002446 0,12945685 ! RNA elongation GO:0006354 90 56 0,000 0,12002446 0,12939972 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,12203297 0,13150708 ! chloride transport GO:0006821 102 57 0,000 0,12203297 0,1314491 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,12203297 0,13139117 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,12203297 0,13133328 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,12203297 0,13127545 ! regulation of actin filament length GO:0030832 118 58 0,000 0,12403696 0,13337248 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,12403696 0,13331381 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,12403696 0,13325518 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,12403696 0,13319661 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,12403696 0,13313809 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,12403696 0,13307962 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,12403696 0,1330212 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,12403696 0,13296283 ! nuclear export GO:0051168 110 59 0,000 0,12603642 0,13504692 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,12803138 0,13712436 ! lipid modification GO:0030258 112 60 0,000 0,12803138 0,13706427 ! DNA catabolic process GO:0006308 94 60 0,000 0,12803138 0,13700423 ! regulation of endocytosis GO:0030100 104 60 0,000 0,12803138 0,13694425 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,12803138 0,13688431 ! adult behavior GO:0030534 104 60 0,000 0,12803138 0,13682443 ! kidney development GO:0001822 133 60 0,000 0,12803138 0,13676461 ! positive regulation of secretion GO:0051047 110 61 0,000 0,13002184 0,13883014 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13002184 0,13876948 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13002184 0,13870889 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13002184 0,13864834 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,13002184 0,13858785 ! regulation of heart contraction GO:0008016 123 61 0,000 0,13002184 0,13852741 ! camera-type eye development GO:0043010 126 61 0,000 0,13002184 0,13846702 ! proton transport GO:0015992 117 61 0,000 0,13002184 0,13840669 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,13002184 0,13834641 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,13200781 0,14039838 ! tRNA processing GO:0008033 102 62 0,000 0,13200781 0,14033728 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,13200781 0,14027624 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,1339893 0,14231994 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,1339893 0,14225809 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,1339893 0,14219629 ! hydrogen transport GO:0006818 121 64 0,000 0,13596633 0,14423176 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,13596633 0,14416916 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1379389 0,14619728 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,1379389 0,14613388 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1379389 0,14607054 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1379389 0,14600725 ! ear development GO:0043583 114 66 0,000 0,13990702 0,14802635 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,13990702 0,14796227 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,13990702 0,14789825 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,13990702 0,14783428 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,1418707 0,14984441 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,1418707 0,14977966 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,1418707 0,14971496 ! secondary metabolic process GO:0019748 125 67 0,000 0,1418707 0,14965031 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,1418707 0,14958572 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,14382996 0,1515861 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,14382996 0,15152073 ! hexose catabolic process GO:0019320 113 68 0,000 0,14382996 0,15145542 ! extracellular matrix organization GO:0030198 146 68 0,000 0,14382996 0,15139017 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,14382996 0,15132497 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,14382996 0,15125983 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,14382996 0,15119474 ! regulation of lipase activity GO:0060191 137 68 0,000 0,14382996 0,15112971 ! adaptive immune response GO:0002250 126 68 0,000 0,14382996 0,15106474 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,14382996 0,15099982 ! cell projection assembly GO:0030031 138 68 0,000 0,14382996 0,15093496 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,14578479 0,15292067 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,14578479 0,15285504 ! urogenital system development GO:0001655 149 69 0,000 0,14578479 0,15278947 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,14578479 0,15272395 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,14578479 0,15265849 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,14578479 0,15259308 ! single fertilization GO:0007338 83 69 0,000 0,14578479 0,15252773 ! cell redox homeostasis GO:0045454 114 70 0,000 0,14773522 0,1545022 ! activation of immune response GO:0002253 120 70 0,000 0,14773522 0,15443609 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,14773522 0,15437003 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,14968125 0,15633659 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,14968125 0,15626978 ! appendage morphogenesis GO:0035107 150 72 0,000 0,15162289 0,15822927 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,15162289 0,15816171 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,15162289 0,1580942 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,15162289 0,15802676 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,15162289 0,15795937 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,15162289 0,15789204 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,15162289 0,15782476 ! appendage development GO:0048736 151 73 0,000 0,15356015 0,15977319 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,15356015 0,15970517 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,15356015 0,15963721 ! acute inflammatory response GO:0002526 118 74 0,000 0,15549304 0,16157784 ! amino acid transport GO:0006865 148 74 0,000 0,15549304 0,16150914 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,15549304 0,1614405 ! transition metal ion transport GO:0000041 143 75 0,000 0,15742158 0,16337337 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15742158 0,163304 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,15742158 0,16323468 ! eye development GO:0001654 155 75 0,000 0,15742158 0,16316543 ! axon guidance GO:0007411 162 75 0,000 0,15742158 0,16309623 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,15934576 0,16501979 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,15934576 0,16494987 ! learning or memory GO:0007611 161 76 0,000 0,15934576 0,16488 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,15934576 0,1648102 ! regulation of blood pressure GO:0008217 134 76 0,000 0,15934576 0,16474045 ! amine catabolic process GO:0009310 136 77 0,000 0,1612656 0,16665477 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1612656 0,1665843 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,1612656 0,16651389 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,1612656 0,16644354 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1612656 0,16637326 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,1612656 0,16630303 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1612656 0,16623286 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,16318112 0,16813643 ! antigen processing and presentation GO:0019882 117 78 0,000 0,16318112 0,16806554 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,16318112 0,16799472 ! blood coagulation GO:0007596 151 79 0,000 0,16509231 0,16989069 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,16509231 0,16981916 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,16509231 0,16974769 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,16509231 0,16967628 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,16509231 0,16960492 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,16509231 0,16953363 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,16699919 0,17141975 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,16699919 0,17134776 ! meiosis GO:0007126 143 81 0,000 0,16890177 0,17322713 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,16890177 0,17315443 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,16890177 0,1730818 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,17080005 0,17495368 ! meiotic cell cycle GO:0051321 144 82 0,000 0,17080005 0,17488036 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,17269406 0,17674553 ! exocytosis GO:0006887 153 83 0,000 0,17269406 0,17667152 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,17269406 0,17659757 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,17269406 0,17652368 GO:0045937|positive regulation of phosphate metabolic process, ! inorganic anion transport GO:0015698 156 83 0,000 0,17269406 0,17644985 ! response to metal ion GO:0010038 158 84 0,000 0,17458379 0,1783061 ! digestion GO:0007586 130 84 0,000 0,17458379 0,17823159 ! regulation of ligase activity GO:0051340 147 84 0,000 0,17458379 0,17815714 ! hemostasis GO:0007599 165 85 0,000 0,17646926 0,18000601 ! negative regulation of transport GO:0051051 164 85 0,000 0,17646926 0,17993089 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,17646926 0,17985582 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,17646926 0,17978082 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,17835047 0,1816216 ! regulation of lyase activity GO:0051339 169 86 0,000 0,17835047 0,18154592 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,17835047 0,18147031 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,18022744 0,18330377 ! alcohol catabolic process GO:0046164 142 87 0,000 0,18022744 0,18322749 ! nucleosome assembly GO:0006334 126 87 0,000 0,18022744 0,18315127 ! regulation of protein transport GO:0051223 165 87 0,000 0,18022744 0,18307511 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,18210018 0,18490056 ! amine biosynthetic process GO:0009309 146 88 0,000 0,18210018 0,18482374 ! sensory perception of smell GO:0007608 117 88 0,000 0,18210018 0,18474698 ! chromatin assembly GO:0031497 128 88 0,000 0,18210018 0,18467029 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,18396869 0,18648776 ! tube morphogenesis GO:0035239 194 89 0,000 0,18396869 0,18641041 ! cellular defense response GO:0006968 123 89 0,000 0,18396869 0,18633313 ! regulation of neurological system process GO:0031644 175 89 0,000 0,18396869 0,18625591 ! response to inorganic substance GO:0010035 173 90 0,000 0,18583298 0,18806544 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,18583298 0,18798757 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,18583298 0,18790976 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,18769307 0,18971211 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,18769307 0,18963365 ! gland development GO:0048732 220 91 0,000 0,18769307 0,18955526 ! defense response to bacterium GO:0042742 112 91 0,000 0,18769307 0,18947693 ! bone development GO:0060348 206 92 0,000 0,18954896 0,19127142 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,18954896 0,19119245 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,18954896 0,19111354 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,19140066 0,19290091 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,19140066 0,19282137 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,19324819 0,19460236 ! female pregnancy GO:0007565 166 94 0,000 0,19324819 0,19452217 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,19324819 0,19444206 ! nucleosome organization GO:0034728 143 95 0,000 0,19509154 0,19621599 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,19509154 0,19613524 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,19509154 0,19605456 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,19509154 0,19597394 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,19509154 0,1958934 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,19509154 0,19581291 ! regulation of T cell activation GO:0050863 175 96 0,000 0,19693073 0,19757773 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,19876578 0,19933694 ! transcription initiation GO:0006352 171 97 0,000 0,19876578 0,19925515 ! regulation of protein localization GO:0032880 188 97 0,000 0,19876578 0,19917342 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,20059668 0,20092566 ! forebrain development GO:0030900 210 98 0,000 0,20059668 0,20084331 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,20059668 0,20076103 ! positive regulation of immune response GO:0050778 175 100 0,000 0,20424609 0,20432973 ! hormone metabolic process GO:0042445 171 100 0,000 0,20424609 0,20424609