pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6240-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 3,000 1,347E-08 3,241E-05 GO:0016446|somatic hypermutation of immunoglobulin genes, ! mismatch repair GO:0006298 46 34 4,000 1,813E-07 2,181E-04 ! positive regulation of helicase activity GO:0051096 11 5 2,000 5,253E-07 4,213E-04 ! muscle cell migration GO:0014812 8 5 2,000 5,253E-07 3,16E-04 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 3,000 7,223E-07 3,476E-04 ! male meiosis GO:0007140 7 6 2,000 1,048E-06 4,201E-04 ! nuclear migration GO:0007097 12 6 2,000 1,048E-06 3,601E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,048E-06 3,151E-04 GO:0031272|regulation of pseudopodium assembly, ! determination of adult lifespan GO:0008340 15 6 2,000 1,048E-06 2,801E-04 ! somatic diversification of immunoglobulins GO:0016445 50 22 3,000 1,351E-06 3,251E-04 ! response to UV GO:0009411 104 53 4,000 1,766E-06 3,862E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 1,828E-06 3,666E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,828E-06 3,384E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,828E-06 3,142E-04 ! negative regulation of DNA recombination GO:0045910 15 7 2,000 1,828E-06 2,933E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,828E-06 2,749E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 1,923E-06 2,722E-04 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 3,000 1,951E-06 2,608E-04 GO:0016444|somatic cell DNA recombination, ! immunoglobulin production GO:0002377 55 25 3,000 2,316E-06 2,933E-04 GO:0002440|production of molecular mediator of immune response, ! insulin receptor signaling pathway GO:0008286 64 26 3,000 2,729E-06 3,283E-04 ! somatic diversification of immune receptors GO:0002200 56 26 3,000 2,729E-06 3,127E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,917E-06 3,191E-04 ! multicellular organismal aging GO:0010259 18 8 2,000 2,917E-06 3,052E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 2,917E-06 2,925E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 4,364E-06 4,2E-04 ! positive regulation of catabolic process GO:0009896 64 32 3,000 6,451E-06 5,97E-04 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 2,000 8,525E-06 7,596E-04 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nucleus localization GO:0051647 19 11 2,000 8,525E-06 7,325E-04 ! negative regulation of DNA metabolic process GO:0051053 61 35 3,000 9,311E-06 7,725E-04 ! regulation of catabolic process GO:0009894 161 76 4,000 1,061E-05 8,507E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 1,133E-05 8,797E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,133E-05 8,522E-04 ! immunoglobulin production during immune response GO:0002381 23 12 2,000 1,133E-05 8,264E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 1,168E-05 8,263E-04 ! response to X-ray GO:0010165 25 13 2,000 1,469E-05 1,01E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,539E-05 1,028E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,95E-05 1,268E-03 ! regulation of protein transport GO:0051223 154 87 4,000 2,053E-05 1,3E-03 GO:0070201|regulation of establishment of protein localization, ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 2,574E-05 1,588E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 2,81E-05 1,69E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 2,81E-05 1,649E-03 ! filopodium assembly GO:0046847 32 16 2,000 2,854E-05 1,635E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 3,332E-05 1,864E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 3,455E-05 1,89E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 3,455E-05 1,848E-03 ! microspike assembly GO:0030035 36 17 2,000 3,455E-05 1,807E-03 ! regulation of protein localization GO:0032880 176 97 4,000 3,474E-05 1,778E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 4,135E-05 2,073E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 5,722E-05 2,809E-03 ! aging GO:0007568 103 55 3,000 5,722E-05 2,753E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 5,745E-05 2,71E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 5,745E-05 2,658E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 5,745E-05 2,608E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 5,745E-05 2,56E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 6,588E-05 2,882E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 7,718E-05 3,316E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 7,718E-05 3,258E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 8,063E-05 3,345E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 8,063E-05 3,288E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 8,603E-05 3,45E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 8,852E-05 3,491E-03 ! regulation of DNA recombination GO:0000018 48 23 2,000 8,852E-05 3,435E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 8,852E-05 3,38E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 1,009E-04 3,793E-03 ! germ cell development GO:0007281 118 65 3,000 1,103E-04 4,084E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,143E-04 4,168E-03 ! interaction with host GO:0051701 62 25 2,000 1,143E-04 4,105E-03 ! cell projection assembly GO:0030031 120 66 3,000 1,171E-04 4,143E-03 ! blastocyst development GO:0001824 49 26 2,000 1,289E-04 4,494E-03 ! female meiosis GO:0007143 7 5 1,000 1,41E-04 4,845E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 1,41E-04 4,777E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,41E-04 4,711E-03 ! anagen GO:0042640 6 5 1,000 1,41E-04 4,646E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,41E-04 4,584E-03 ! microvillus organization GO:0032528 7 5 1,000 1,41E-04 4,522E-03 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 1,41E-04 4,463E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 1,41E-04 4,405E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 1,41E-04 4,349E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,41E-04 4,293E-03 ! decidualization GO:0046697 11 5 1,000 1,41E-04 4,24E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,41E-04 4,187E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 1,41E-04 4,136E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,446E-04 4,191E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,796E-04 5,145E-03 ! meiosis GO:0007126 121 74 3,000 1,827E-04 5,17E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 3,000 1,924E-04 5,382E-03 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 1,000 2,109E-04 5,834E-03 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,109E-04 5,767E-03 ! male sex determination GO:0030238 15 6 1,000 2,109E-04 5,702E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,109E-04 5,639E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 2,109E-04 5,577E-03 ! hair follicle maturation GO:0048820 7 6 1,000 2,109E-04 5,516E-03 ! maternal placenta development GO:0001893 12 6 1,000 2,109E-04 5,457E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 2,418E-04 6,19E-03 ! negative regulation of protein transport GO:0051224 69 33 2,000 2,653E-04 6,718E-03 ! placenta development GO:0001890 53 34 2,000 2,901E-04 7,272E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 2,901E-04 7,197E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,946E-04 7,232E-03 ! synaptonemal complex assembly GO:0007130 10 7 1,000 2,946E-04 7,159E-03 GO:0070193|synaptonemal complex organization, ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,946E-04 7,088E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,946E-04 7,017E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 2,946E-04 6,949E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,946E-04 6,881E-03 ! centrosome duplication GO:0051298 13 7 1,000 2,946E-04 6,815E-03 ! fibrinolysis GO:0042730 10 7 1,000 2,946E-04 6,75E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 2,946E-04 6,686E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,946E-04 6,624E-03 ! negative regulation of transport GO:0051051 153 84 3,000 2,975E-04 6,628E-03 ! mitochondrion organization GO:0007005 148 86 3,000 3,255E-04 7,186E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 3,443E-04 7,531E-03 ! meiosis I GO:0007127 65 37 2,000 3,736E-04 8,099E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 3,736E-04 8,027E-03 ! glycogen metabolic process GO:0005977 61 37 2,000 3,736E-04 7,956E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,918E-04 8,269E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,918E-04 8,197E-03 ! ER overload response GO:0006983 12 8 1,000 3,918E-04 8,127E-03 ! negative regulation of translational initiation GO:0045947 10 8 1,000 3,918E-04 8,057E-03 ! response to UV-B GO:0010224 16 8 1,000 3,918E-04 7,989E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 3,918E-04 7,922E-03 ! blastocyst growth GO:0001832 19 8 1,000 3,918E-04 7,856E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 3,918E-04 7,791E-03 ! glucan metabolic process GO:0044042 62 38 2,000 4,046E-04 7,978E-03 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 2,000 4,371E-04 8,549E-03 ! ear morphogenesis GO:0042471 60 39 2,000 4,371E-04 8,481E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 4,386E-04 8,442E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 4,947E-04 9,446E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 5,025E-04 9,52E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,025E-04 9,445E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 5,025E-04 9,372E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 5,025E-04 9,3E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,025E-04 9,229E-03 ! receptor clustering GO:0043113 18 9 1,000 5,025E-04 9,159E-03 ! motor axon guidance GO:0008045 16 9 1,000 5,025E-04 9,09E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 5,025E-04 9,023E-03 ! postreplication repair GO:0006301 22 9 1,000 5,025E-04 8,956E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 5,025E-04 8,89E-03 ! skeletal muscle tissue development GO:0007519 186 99 3,000 5,557E-04 9,76E-03 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 3,000 5,772E-04 0,01006354 ! energy reserve metabolic process GO:0006112 74 43 2,000 5,837E-04 0,01010416 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 5,837E-04 0,01003199 ! double-strand break repair GO:0006302 81 44 2,000 6,247E-04 0,01066032 ! developmental growth GO:0048589 82 44 2,000 6,247E-04 0,01058525 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 6,266E-04 0,01054217 ! synapsis GO:0007129 13 10 1,000 6,266E-04 0,01046896 GO:0070192|chromosome organization involved in meiosis, ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 6,266E-04 0,01039676 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 6,266E-04 0,01032555 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 6,266E-04 0,01025531 ! glucan biosynthetic process GO:0009250 14 10 1,000 6,266E-04 0,01018602 GO:0005978|glycogen biosynthetic process, ! multicellular organism growth GO:0035264 18 10 1,000 6,266E-04 0,01011765 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 6,266E-04 0,0100502 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 6,266E-04 9,984E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 6,266E-04 9,918E-03 ! blastocyst formation GO:0001825 17 10 1,000 6,266E-04 9,853E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 7,121E-04 0,01112584 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 7,639E-04 0,01185793 ! detection of mechanical stimulus GO:0050982 22 11 1,000 7,639E-04 0,01178192 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,639E-04 0,01170688 ! DNA methylation GO:0006306 19 11 1,000 7,639E-04 0,01163278 GO:0006305|DNA alkylation, ! oocyte differentiation GO:0009994 18 11 1,000 7,639E-04 0,01155962 ! thymus development GO:0048538 27 11 1,000 7,639E-04 0,01148737 ! regulation of embryonic development GO:0045995 27 11 1,000 7,639E-04 0,01141602 ! immunoglobulin mediated immune response GO:0016064 83 49 2,000 8,572E-04 0,0127312 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 2,000 9,094E-04 0,0134238 ! virus-host interaction GO:0019048 29 12 1,000 9,144E-04 0,01341537 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 9,144E-04 0,01333407 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 9,144E-04 0,01325374 ! entry into host cell GO:0030260 32 12 1,000 9,144E-04 0,01317438 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 9,144E-04 0,01309596 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,144E-04 0,01301847 ! T cell homeostasis GO:0043029 25 12 1,000 9,144E-04 0,01294189 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 9,144E-04 0,0128662 GO:0042130|negative regulation of T cell proliferation, ! response to estrogen stimulus GO:0043627 93 51 2,000 9,636E-04 0,0134794 ! positive regulation of growth GO:0045927 90 52 2,000 1,02E-03 0,01418297 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,078E-03 0,01490641 GO:0000725|recombinational repair, ! plasma membrane organization GO:0007009 24 13 1,000 1,078E-03 0,01482123 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,078E-03 0,01473702 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,078E-03 0,01465376 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,078E-03 0,01457143 ! embryonic placenta development GO:0001892 23 13 1,000 1,078E-03 0,01449003 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,078E-03 0,01440953 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 1,201E-03 0,01596048 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,255E-03 0,01658528 ! regulation of S phase GO:0033261 23 14 1,000 1,255E-03 0,01649465 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,255E-03 0,01640501 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,255E-03 0,01631633 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,255E-03 0,01622861 ! response to gamma radiation GO:0010332 28 14 1,000 1,255E-03 0,01614183 ! protein-chromophore linkage GO:0018298 19 14 1,000 1,255E-03 0,01605597 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,255E-03 0,01597101 ! skeletal muscle fiber development GO:0048741 111 56 2,000 1,265E-03 0,01602105 ! regulation of DNA replication GO:0006275 101 56 2,000 1,265E-03 0,01593717 ! muscle fiber development GO:0048747 112 57 2,000 1,332E-03 0,01668908 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,444E-03 0,01800157 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,444E-03 0,01790878 ! skeletal system morphogenesis GO:0048705 105 59 2,000 1,472E-03 0,01815704 ! establishment of organelle localization GO:0051656 109 59 2,000 1,472E-03 0,0180644 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,62E-03 0,01978833 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,646E-03 0,02000417 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,646E-03 0,01990364 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 1,646E-03 0,01980412 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,646E-03 0,0197056 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,646E-03 0,01960804 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,646E-03 0,01951145 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ear development GO:0043583 103 62 2,000 1,698E-03 0,02002599 ! viral reproductive process GO:0022415 126 62 2,000 1,698E-03 0,0199283 ! gonad development GO:0008406 98 62 2,000 1,698E-03 0,01983157 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,778E-03 0,02066581 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,778E-03 0,02056645 ! lymphocyte mediated immunity GO:0002449 114 64 2,000 1,86E-03 0,02141589 ! signal complex assembly GO:0007172 41 17 1,000 1,861E-03 0,02132309 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,861E-03 0,02122204 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,861E-03 0,02112193 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 1,861E-03 0,02102277 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,945E-03 0,02186754 ! developmental maturation GO:0021700 116 66 2,000 2,032E-03 0,0227399 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,089E-03 0,02326456 ! centrosome cycle GO:0007098 25 18 1,000 2,089E-03 0,02315735 ! positive regulation of proteolysis GO:0045862 31 18 1,000 2,089E-03 0,02305112 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,089E-03 0,02294587 ! activation of MAPK activity GO:0000187 115 67 2,000 2,121E-03 0,02320113 ! adaptive immune response GO:0002250 119 67 2,000 2,121E-03 0,02309615 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 2,213E-03 0,02398748 ! viral reproduction GO:0016032 134 68 2,000 2,213E-03 0,02387991 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 2,329E-03 0,02501106 ! lipid phosphorylation GO:0046834 35 19 1,000 2,329E-03 0,0248999 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 2,329E-03 0,02478972 ! neuromuscular junction development GO:0007528 34 19 1,000 2,329E-03 0,02468052 ! reproductive structure development GO:0048608 113 71 2,000 2,504E-03 0,02641877 ! B cell activation GO:0042113 160 71 2,000 2,504E-03 0,02630341 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 2,581E-03 0,02699833 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,581E-03 0,02688145 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,581E-03 0,02676559 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 2,581E-03 0,02665071 ! negative regulation of T cell activation GO:0050868 40 20 1,000 2,581E-03 0,02653682 ! negative regulation of translation GO:0017148 29 20 1,000 2,581E-03 0,0264239 ! negative regulation of coagulation GO:0050819 29 20 1,000 2,581E-03 0,02631193 ! regulation of transcription factor activity GO:0051090 126 74 2,000 2,816E-03 0,02859002 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 2,000 2,816E-03 0,0284699 ! organelle localization GO:0051640 136 74 2,000 2,816E-03 0,02835078 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 2,846E-03 0,02852638 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 2,846E-03 0,02840801 ! cell aging GO:0007569 44 21 1,000 2,846E-03 0,02829062 ! oogenesis GO:0048477 36 21 1,000 2,846E-03 0,0281742 ! DNA modification GO:0006304 34 21 1,000 2,846E-03 0,02805873 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,846E-03 0,02794421 ! cell-matrix adhesion GO:0007160 163 75 2,000 2,926E-03 0,02861332 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 2,926E-03 0,02849747 ! development of primary sexual characteristics GO:0045137 124 76 2,000 3,037E-03 0,02946824 ! glutamate signaling pathway GO:0007215 41 22 1,000 3,122E-03 0,03017026 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 3,122E-03 0,03004958 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,122E-03 0,02992986 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 3,122E-03 0,02981109 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,122E-03 0,02969326 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,122E-03 0,02957635 ! protein stabilization GO:0050821 39 22 1,000 3,122E-03 0,02946037 ! blood coagulation GO:0007596 146 78 2,000 3,269E-03 0,03072435 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 2,000 3,269E-03 0,0306048 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,411E-03 0,03181232 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,411E-03 0,03168949 ! gluconeogenesis GO:0006094 33 23 1,000 3,411E-03 0,0315676 ! sex determination GO:0007530 47 23 1,000 3,411E-03 0,03144666 ! negative regulation of catabolic process GO:0009895 50 23 1,000 3,411E-03 0,03132663 ! response to hypoxia GO:0001666 171 81 2,000 3,636E-03 0,03326658 ! cell-substrate adhesion GO:0031589 171 81 2,000 3,636E-03 0,03314057 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,712E-03 0,03370436 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 3,712E-03 0,03357765 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,712E-03 0,03345189 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,712E-03 0,03332707 ! leukocyte homeostasis GO:0001776 44 24 1,000 3,712E-03 0,03320318 ! protein tetramerization GO:0051262 52 24 1,000 3,712E-03 0,0330802 ! response to drug GO:0042493 143 82 2,000 3,764E-03 0,03341907 ! response to oxygen levels GO:0070482 176 83 2,000 3,895E-03 0,03445055 ! myelination GO:0042552 45 25 1,000 4,025E-03 0,035474 ! vasculogenesis GO:0001570 46 25 1,000 4,025E-03 0,03534453 ! negative regulation of DNA replication GO:0008156 42 25 1,000 4,025E-03 0,03521601 ! receptor metabolic process GO:0043112 46 25 1,000 4,025E-03 0,03508841 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 4,025E-03 0,03496174 ! somitogenesis GO:0001756 43 25 1,000 4,025E-03 0,03483598 ! regulation of blood coagulation GO:0030193 40 25 1,000 4,025E-03 0,03471112 ! hemostasis GO:0007599 158 84 2,000 4,028E-03 0,03461105 ! oxidative phosphorylation GO:0006119 133 86 2,000 4,303E-03 0,03684 ! initiation of viral infection GO:0019059 57 26 1,000 4,35E-03 0,03711204 ! pyruvate metabolic process GO:0006090 38 26 1,000 4,35E-03 0,0369809 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 4,35E-03 0,03685069 ! molting cycle process GO:0022404 50 26 1,000 4,35E-03 0,03672139 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 4,35E-03 0,03659299 ! microtubule organizing center organization GO:0031023 39 26 1,000 4,35E-03 0,03646549 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,35E-03 0,03633887 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,35E-03 0,03621313 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 4,35E-03 0,03608826 ! response to estradiol stimulus GO:0032355 40 26 1,000 4,35E-03 0,03596425 ! positive regulation of nuclear division GO:0051785 40 26 1,000 4,35E-03 0,03584108 GO:0045840|positive regulation of mitosis, ! regulation of DNA binding GO:0051101 155 88 2,000 4,588E-03 0,03767822 ! gland development GO:0048732 206 88 2,000 4,588E-03 0,03755007 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 4,686E-03 0,03822038 ! protein amino acid acylation GO:0043543 55 27 1,000 4,686E-03 0,03809126 ! male gonad development GO:0008584 44 27 1,000 4,686E-03 0,03796301 ! regulation of chromosome organization GO:0033044 42 27 1,000 4,686E-03 0,03783561 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 4,686E-03 0,03770907 ! cellular defense response GO:0006968 114 89 2,000 4,736E-03 0,03797894 ! regulation of cell cycle process GO:0010564 149 90 2,000 4,885E-03 0,03905131 ! sex differentiation GO:0007548 145 90 2,000 4,885E-03 0,038922 ! negative regulation of protein modification process GO:0031400 60 28 1,000 5,034E-03 0,03997503 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 5,034E-03 0,03984353 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 5,034E-03 0,0397129 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 5,352E-03 0,04208459 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 5,394E-03 0,04227243 ! response to organic cyclic substance GO:0014070 55 29 1,000 5,394E-03 0,04213518 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 5,394E-03 0,04199882 ! tissue homeostasis GO:0001894 48 29 1,000 5,394E-03 0,04186334 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 1,000 5,394E-03 0,04172873 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 5,765E-03 0,04445642 ! ensheathment of neurons GO:0007272 57 30 1,000 5,765E-03 0,04431439 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 5,765E-03 0,04417326 ! response to heat GO:0009408 50 30 1,000 5,765E-03 0,04403303 ! protein ubiquitination GO:0016567 217 97 2,000 6,015E-03 0,04580103 ! inner ear morphogenesis GO:0042472 47 31 1,000 6,147E-03 0,04665779 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 6,147E-03 0,04651106 ! iron ion homeostasis GO:0055072 54 31 1,000 6,147E-03 0,04636526 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 6,147E-03 0,04622037 GO:0043433|negative regulation of transcription factor activity, ! response to mechanical stimulus GO:0009612 57 32 1,000 6,541E-03 0,0490273 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 6,541E-03 0,04887504 ! hexose biosynthetic process GO:0019319 48 32 1,000 6,541E-03 0,04872373 ! peripheral nervous system development GO:0007422 64 32 1,000 6,541E-03 0,04857335 ! DNA damage checkpoint GO:0000077 71 33 1,000 6,946E-03 0,05142131 ! negative regulation of secretion GO:0051048 63 35 1,000 7,789E-03 0,05748511 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 7,789E-03 0,05730931 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 7,789E-03 0,05713459 ! female gonad development GO:0008585 58 35 1,000 7,789E-03 0,05696093 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 8,227E-03 0,05998114 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 8,227E-03 0,05979993 ! maintenance of protein location in cell GO:0032507 86 36 1,000 8,227E-03 0,05961981 ! DNA integrity checkpoint GO:0031570 75 36 1,000 8,227E-03 0,05944077 ! regulation of proteolysis GO:0030162 72 36 1,000 8,227E-03 0,05926281 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 8,227E-03 0,0590859 ! negative regulation of cell activation GO:0050866 65 36 1,000 8,227E-03 0,05891005 ! negative regulation of DNA binding GO:0043392 68 37 1,000 8,676E-03 0,06193911 ! regulation of protein stability GO:0031647 73 37 1,000 8,676E-03 0,06175586 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 9,135E-03 0,06483493 ! carbohydrate homeostasis GO:0033500 53 38 1,000 9,135E-03 0,06464424 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 9,135E-03 0,06445467 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 9,135E-03 0,0642662 ! learning GO:0007612 77 39 1,000 9,605E-03 0,06737684 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 9,605E-03 0,06718098 ! segmentation GO:0035282 67 39 1,000 9,605E-03 0,06698625 ! regulation of action potential in neuron GO:0019228 73 39 1,000 9,605E-03 0,06679265 ! negative regulation of binding GO:0051100 72 40 1,000 0,010086 0,06993347 ! maintenance of protein location GO:0045185 91 40 1,000 0,010086 0,06973251 ! cytokinesis GO:0000910 72 40 1,000 0,010086 0,06953271 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,01057723 0,0727109 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01057723 0,07250375 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01057723 0,07229777 ! female gamete generation GO:0007292 61 41 1,000 0,01057723 0,07209296 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01107887 0,07529873 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01107887 0,07508662 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01107887 0,07487571 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01107887 0,07466597 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01159082 0,0778981 ! glucose transport GO:0015758 65 43 1,000 0,01159082 0,07768112 ! hexose transport GO:0008645 67 44 1,000 0,01211302 0,08095534 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,01211302 0,08073108 ! biopolymer methylation GO:0043414 84 44 1,000 0,01211302 0,08050807 ! B cell differentiation GO:0030183 107 44 1,000 0,01211302 0,08028629 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01211302 0,08006572 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01211302 0,07984636 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01264537 0,08312774 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01264537 0,08290123 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,01264537 0,08267596 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 0,01264537 0,08245191 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,01318779 0,08575626 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01318779 0,08552511 ! pigmentation GO:0043473 100 46 1,000 0,01318779 0,0852952 ! endosome transport GO:0016197 108 47 1,000 0,0137402 0,08862979 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0137402 0,08839281 ! methylation GO:0032259 90 47 1,000 0,0137402 0,08815709 ! cellular component disassembly GO:0022411 86 48 1,000 0,01430251 0,09152085 ! activation of caspase activity GO:0006919 84 48 1,000 0,01430251 0,09127809 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01430251 0,09103662 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01430251 0,09079641 ! regulation of action potential GO:0001508 95 49 1,000 0,01487465 0,09418003 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01487465 0,09393284 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01487465 0,09368694 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01487465 0,09344233 ! inner ear development GO:0048839 79 50 1,000 0,01545654 0,09684486 ! histone modification GO:0016570 91 50 1,000 0,01545654 0,09659331 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01545654 0,09634307 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01545654 0,09609412 ! positive regulation of binding GO:0051099 78 51 1,000 0,01604808 0,09951466 ! viral infectious cycle GO:0019058 99 51 1,000 0,01604808 0,09925884 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,01604808 0,09900433 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01604808 0,09875112 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01664921 0,1021888 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01664921 0,10192878 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01664921 0,10167008 ! amino acid activation GO:0043038 92 52 1,000 0,01664921 0,10141268 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,01664921 0,10115659 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,01725985 0,10460251 ! regulation of translational initiation GO:0006446 82 53 1,000 0,01725985 0,10433969 ! cell maturation GO:0048469 100 53 1,000 0,01725985 0,10407819 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01725985 0,10381799 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01787991 0,10727945 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01850931 0,11077962 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01850931 0,11050473 ! heart morphogenesis GO:0003007 97 55 1,000 0,01850931 0,1102312 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01850931 0,10995903 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01878469 0,11132009 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01878469 0,11104658 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01878469 0,1107744 ! neuron fate determination GO:0048664 7 5 0,000 0,01878469 0,11050356 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01878469 0,11023404 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01878469 0,10996583 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01878469 0,10969892 ! polyol transport GO:0015791 12 5 0,000 0,01878469 0,10943331 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01878469 0,10916898 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01878469 0,10890592 ! response to superoxide GO:0000303 10 5 0,000 0,01878469 0,10864413 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01878469 0,10838359 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01878469 0,1081243 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01878469 0,10786625 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01878469 0,10760942 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01878469 0,10735382 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01878469 0,10709942 ! cobalt ion transport GO:0006824 11 5 0,000 0,01878469 0,10684623 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01878469 0,10659424 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01878469 0,10634343 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01878469 0,1060938 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01878469 0,10584533 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01878469 0,10559803 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01878469 0,10535188 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01878469 0,10510688 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01878469 0,10486301 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01878469 0,10462027 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01878469 0,10437865 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01878469 0,10413815 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01878469 0,10389875 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01878469 0,10366045 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01878469 0,10342324 ! negative chemotaxis GO:0050919 14 5 0,000 0,01878469 0,10318712 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01878469 0,10295207 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01878469 0,10271808 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01878469 0,10248516 ! behavioral response to pain GO:0048266 9 5 0,000 0,01878469 0,1022533 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01878469 0,10202248 ! Notch receptor processing GO:0007220 8 5 0,000 0,01878469 0,1017927 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01878469 0,10156395 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,01878469 0,10133623 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01878469 0,10110952 ! copulation GO:0007620 9 5 0,000 0,01878469 0,10088383 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01878469 0,10065915 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01878469 0,10043546 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01878469 0,10021276 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01878469 0,09999106 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01878469 0,09977032 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01878469 0,09955057 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01878469 0,09933177 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01878469 0,09911394 ! grooming behavior GO:0007625 6 5 0,000 0,01878469 0,09889706 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01878469 0,09868113 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01878469 0,09846614 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01878469 0,09825208 ! response to protozoan GO:0001562 10 5 0,000 0,01878469 0,09803895 ! lymph vessel development GO:0001945 10 5 0,000 0,01878469 0,09782675 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01878469 0,09761546 ! endochondral ossification GO:0001958 16 5 0,000 0,01878469 0,09740508 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01878469 0,09719561 ! parathyroid gland development GO:0060017 13 5 0,000 0,01878469 0,09698703 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01878469 0,09677935 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01878469 0,09657256 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01878469 0,09636665 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01878469 0,09616161 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01878469 0,09595745 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01878469 0,09575415 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01878469 0,09555171 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01878469 0,09535012 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01878469 0,09514938 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01878469 0,09494949 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01878469 0,09475043 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01878469 0,09455221 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01878469 0,09435482 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01878469 0,09415824 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01878469 0,09396249 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01878469 0,09376755 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01878469 0,09357341 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01878469 0,09338008 ! histidine catabolic process GO:0006548 6 5 0,000 0,01878469 0,09318754 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01878469 0,0929958 ! valine metabolic process GO:0006573 10 5 0,000 0,01878469 0,09280484 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01878469 0,09261467 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01878469 0,09242527 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01878469 0,09223665 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01878469 0,09204879 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01878469 0,0918617 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01878469 0,09167537 ! polyol catabolic process GO:0046174 7 5 0,000 0,01878469 0,09148979 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01878469 0,09130496 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01878469 0,09112088 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01878469 0,09093754 ! mitochondrial fission GO:0000266 8 5 0,000 0,01878469 0,09075493 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01878469 0,09057306 ! mRNA transcription GO:0009299 9 5 0,000 0,01878469 0,09039191 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01878469 0,09021149 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01878469 0,09003179 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01878469 0,0898528 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01878469 0,08967452 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01878469 0,08949694 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01878469 0,08932007 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01878469 0,0891439 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01878469 0,08896842 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01878469 0,08879363 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01878469 0,08861952 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01878469 0,0884461 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01878469 0,08827335 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01878469 0,08810128 ! forebrain neuron development GO:0021884 13 5 0,000 0,01878469 0,08792988 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01878469 0,08775914 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01878469 0,08758906 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01878469 0,08741965 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01878469 0,08725088 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01878469 0,08708277 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01878469 0,0869153 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01878469 0,08674848 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01878469 0,08658229 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01878469 0,08641674 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01878469 0,08625183 ! basic amino acid transport GO:0015802 11 5 0,000 0,01878469 0,08608754 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01878469 0,08592387 ! depyrimidination GO:0045008 10 5 0,000 0,01878469 0,08576083 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01878469 0,0855984 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01878469 0,08543659 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01878469 0,08527539 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01878469 0,0851148 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01878469 0,08495481 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01878469 0,08479542 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01878469 0,08463662 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01878469 0,08447842 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01878469 0,08432082 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01878469 0,08416379 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01878469 0,08400735 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01878469 0,0838515 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01878469 0,08369622 ! response to arsenic GO:0046685 10 5 0,000 0,01878469 0,08354151 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01878469 0,08338737 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01878469 0,08323381 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01878469 0,0830808 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01878469 0,08292836 ! response to cadmium ion GO:0046686 7 5 0,000 0,01878469 0,08277648 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01878469 0,08262515 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01878469 0,08247437 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01878469 0,08232415 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01878469 0,08217447 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01878469 0,08202533 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01878469 0,08187673 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01878469 0,08172867 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01878469 0,08158115 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01878469 0,08143416 ! neural tube patterning GO:0021532 7 5 0,000 0,01878469 0,08128769 ! embryonic cleavage GO:0040016 6 5 0,000 0,01878469 0,08114175 ! peroxisome fission GO:0016559 5 5 0,000 0,01878469 0,08099634 ! histone demethylation GO:0016577 10 5 0,000 0,01878469 0,08085144 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01878469 0,08070707 ! mitotic recombination GO:0006312 9 5 0,000 0,01878469 0,0805632 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01878469 0,08041985 ! metaphase plate congression GO:0051310 7 5 0,000 0,01878469 0,08027701 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01878469 0,08013468 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01878469 0,07999284 ! enteric nervous system development GO:0048484 8 5 0,000 0,01878469 0,07985151 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01878469 0,07971068 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01878469 0,07957035 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01878469 0,0794305 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01878469 0,07929115 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01878469 0,07915229 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01878469 0,07901391 ! plasminogen activation GO:0031639 5 5 0,000 0,01878469 0,07887602 ! B cell homeostasis GO:0001782 13 5 0,000 0,01878469 0,0787386 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01878469 0,07860166 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01878469 0,0784652 ! metaphase GO:0051323 8 5 0,000 0,01878469 0,07832921 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01878469 0,0781937 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01878469 0,07805865 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01878469 0,07792406 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01878469 0,07778994 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01878469 0,07765628 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01878469 0,07752308 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01878469 0,07739034 ! response to redox state GO:0051775 5 5 0,000 0,01878469 0,07725805 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01878469 0,07712621 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01878469 0,07699482 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01878469 0,07686387 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01878469 0,07673337 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01878469 0,07660332 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01878469 0,0764737 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01878469 0,07634452 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01878469 0,07621578 ! striatum development GO:0021756 9 5 0,000 0,01878469 0,07608747 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01878469 0,07595959 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01878469 0,07583214 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01878469 0,07570512 ! glial cell migration GO:0008347 11 5 0,000 0,01878469 0,07557852 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01878469 0,07545235 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01878469 0,07532659 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01878469 0,07520126 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01878469 0,07507634 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01878469 0,07495184 ! neuroprotection GO:0043526 6 5 0,000 0,01878469 0,07482774 ! neural plate development GO:0001840 8 5 0,000 0,01878469 0,07470406 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01878469 0,07458079 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01878469 0,07445792 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01878469 0,07433546 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01878469 0,07421339 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01878469 0,07409173 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01878469 0,07397047 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01878469 0,0738496 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01878469 0,07372913 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01878469 0,07360905 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01878469 0,07348936 ! spindle assembly GO:0051225 6 5 0,000 0,01878469 0,07337006 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01878469 0,07325115 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01878469 0,07313262 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01878469 0,07301447 ! drug metabolic process GO:0017144 6 5 0,000 0,01878469 0,0728967 ! stem cell division GO:0017145 11 5 0,000 0,01878469 0,07277932 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,01878469 0,07266231 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01878469 0,07254568 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01878469 0,07242942 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01878469 0,07231353 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01914798 0,07359433 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01914798 0,07347696 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01979585 0,07584205 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,01979585 0,07572147 ! lipid modification GO:0030258 97 57 1,000 0,01979585 0,07560128 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01979585 0,07548147 ! maintenance of location GO:0051235 118 57 1,000 0,01979585 0,07536203 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02045282 0,0777401 ! DNA catabolic process GO:0006308 86 59 1,000 0,02111883 0,08014495 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02111883 0,08001874 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02249944 0,08511579 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02249944 0,08498217 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02249944 0,08484897 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02249944 0,08471619 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02249944 0,08458382 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02249944 0,08445186 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02249944 0,08432032 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02249944 0,08418918 ! sleep GO:0030431 13 6 0,000 0,02249944 0,08405845 ! response to oxygen radical GO:0000305 11 6 0,000 0,02249944 0,08392813 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02249944 0,08379821 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02249944 0,08366869 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02249944 0,08353958 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02249944 0,08341086 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02249944 0,08328253 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02249944 0,0831546 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02249944 0,08302706 ! forebrain regionalization GO:0021871 8 6 0,000 0,02249944 0,08289992 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02249944 0,08277316 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02249944 0,08264679 ! response to zinc ion GO:0010043 9 6 0,000 0,02249944 0,0825208 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02249944 0,0823952 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02249944 0,08226998 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02249944 0,08214514 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02249944 0,08202067 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02249944 0,08189659 ! malate metabolic process GO:0006108 11 6 0,000 0,02249944 0,08177288 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02249944 0,08164954 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02249944 0,08152657 ! protein refolding GO:0042026 15 6 0,000 0,02249944 0,08140398 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02249944 0,08128175 ! opsonization GO:0008228 8 6 0,000 0,02249944 0,08115989 ! mating behavior GO:0007617 7 6 0,000 0,02249944 0,08103839 ! neuron remodeling GO:0016322 15 6 0,000 0,02249944 0,08091726 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02249944 0,08079648 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02249944 0,08067607 ! equilibrioception GO:0050957 14 6 0,000 0,02249944 0,08055602 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02249944 0,08043632 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02249944 0,08031698 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02249944 0,08019799 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02249944 0,08007936 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02249944 0,07996107 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02249944 0,07984313 ! toxin metabolic process GO:0009404 11 6 0,000 0,02249944 0,07972554 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02249944 0,0796083 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02249944 0,0794914 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02249944 0,07937485 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02249944 0,07925863 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02249944 0,07914276 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02249944 0,07902722 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02249944 0,07891202 ! thymic T cell selection GO:0045061 12 6 0,000 0,02249944 0,07879715 ! protein lipoylation GO:0009249 10 6 0,000 0,02249944 0,07868262 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02249944 0,07856843 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02249944 0,07845456 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02249944 0,07834102 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02249944 0,07822781 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02249944 0,07811493 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02249944 0,07800237 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02249944 0,07789014 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02249944 0,07777823 ! hyperosmotic response GO:0006972 9 6 0,000 0,02249944 0,07766664 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02249944 0,07755537 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02249944 0,07744441 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02249944 0,07733378 ! urea metabolic process GO:0019627 7 6 0,000 0,02249944 0,07722346 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02249944 0,07711345 ! neutrophil activation GO:0042119 8 6 0,000 0,02249944 0,07700376 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02249944 0,07689438 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02249944 0,07678531 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02249944 0,07667655 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02249944 0,0765681 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02249944 0,07645995 ! neuron apoptosis GO:0051402 9 6 0,000 0,02249944 0,07635211 ! nucleoside salvage GO:0043174 9 6 0,000 0,02249944 0,07624457 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02249944 0,07613733 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02249944 0,0760304 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02249944 0,07592377 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02249944 0,07581743 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02249944 0,07571139 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02249944 0,07560565 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02249944 0,0755002 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02249944 0,07539505 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02249944 0,07529019 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02249944 0,07518562 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02249944 0,07508134 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02249944 0,07497735 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02249944 0,07487364 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02249944 0,07477023 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02249944 0,0746671 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02249944 0,07456425 ! neural nucleus development GO:0048857 14 6 0,000 0,02249944 0,07446168 ! astrocyte development GO:0014002 15 6 0,000 0,02249944 0,0743594 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02249944 0,0742574 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02249944 0,07415568 ! interaction with symbiont GO:0051702 13 6 0,000 0,02249944 0,07405423 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02249944 0,07395307 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02249944 0,07385218 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02249944 0,07375156 ! response to copper ion GO:0046688 10 6 0,000 0,02249944 0,07365122 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02249944 0,07355115 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02249944 0,07345135 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02249944 0,07335182 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02249944 0,07325256 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02249944 0,07315357 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02249944 0,07305485 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02249944 0,07295639 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02249944 0,0728582 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02249944 0,07276028 ! Schwann cell development GO:0014044 15 6 0,000 0,02249944 0,07266261 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02249944 0,07256521 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02249944 0,07246807 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02249944 0,07237118 ! subpallium development GO:0021544 10 6 0,000 0,02249944 0,07227456 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02249944 0,07217819 ! histone ubiquitination GO:0016574 8 6 0,000 0,02249944 0,07208208 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02249944 0,07198623 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02249944 0,07189063 ! G2 phase GO:0051319 16 6 0,000 0,02249944 0,07179529 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02249944 0,07170019 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02249944 0,07160535 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02249944 0,07151076 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02249944 0,07141642 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02249944 0,07132233 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02249944 0,07122848 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02249944 0,07113488 ! receptor internalization GO:0031623 10 6 0,000 0,02249944 0,07104153 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02249944 0,07094842 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02249944 0,07085556 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02249944 0,07076293 ! protein deubiquitination GO:0016579 14 6 0,000 0,02249944 0,07067055 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02249944 0,07057842 ! protein destabilization GO:0031648 9 6 0,000 0,02249944 0,07048652 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02249944 0,07039486 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02249944 0,07030343 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02249944 0,07021225 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02249944 0,0701213 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02249944 0,07003059 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02249944 0,06994011 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02249944 0,06984986 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02249944 0,06975985 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02249944 0,06967007 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02249944 0,06958052 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02249944 0,0694912 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02249944 0,06940211 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02249944 0,06931325 ! catecholamine transport GO:0051937 9 6 0,000 0,02249944 0,06922461 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02249944 0,0691362 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02249944 0,06904802 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02249944 0,06896006 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02249944 0,06887232 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02249944 0,06878481 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02249944 0,06869752 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02249944 0,06861045 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02249944 0,0685236 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02249944 0,06843697 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02249944 0,06835056 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02249944 0,06826437 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0231703 0,07021126 ! regulation of mitosis GO:0007088 105 63 1,000 0,02387169 0,07224564 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,02387169 0,07215487 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,02458173 0,07420784 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 1,000 0,02458173 0,07411485 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,02530036 0,07618606 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,02602749 0,07827769 ! actin filament organization GO:0007015 148 66 1,000 0,02602749 0,07817996 ! tRNA transcription GO:0009304 14 7 0,000 0,02620025 0,07860074 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02620025 0,07850285 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02620025 0,07840521 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02620025 0,07830782 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02620025 0,07821066 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02620025 0,07811374 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02620025 0,07801707 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02620025 0,07792063 ! prostate gland development GO:0030850 13 7 0,000 0,02620025 0,07782443 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02620025 0,07772847 ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02620025 0,07763275 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02620025 0,07753726 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02620025 0,077442 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02620025 0,07734698 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02620025 0,0772522 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02620025 0,07715764 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02620025 0,07706332 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02620025 0,07696922 ! glycolipid transport GO:0046836 10 7 0,000 0,02620025 0,07687536 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02620025 0,07678172 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02620025 0,07668831 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02620025 0,07659513 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02620025 0,07650217 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02620025 0,07640944 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02620025 0,07631694 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02620025 0,07622466 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02620025 0,0761326 ! mRNA stabilization GO:0048255 18 7 0,000 0,02620025 0,07604076 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02620025 0,07594915 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02620025 0,07585775 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02620025 0,07576658 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02620025 0,07567562 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02620025 0,07558488 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02620025 0,07549436 ! lipoprotein transport GO:0042953 14 7 0,000 0,02620025 0,07540406 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02620025 0,07531397 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02620025 0,0752241 ! rhythmic behavior GO:0007622 15 7 0,000 0,02620025 0,07513444 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02620025 0,07504499 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02620025 0,07495576 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02620025 0,07486674 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02620025 0,07477793 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02620025 0,07468933 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02620025 0,07460094 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02620025 0,07451276 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02620025 0,07442478 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02620025 0,07433702 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02620025 0,07424946 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02620025 0,07416211 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02620025 0,07407496 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02620025 0,07398802 ! spinal cord patterning GO:0021511 13 7 0,000 0,02620025 0,07390128 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02620025 0,07381474 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02620025 0,07372841 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02620025 0,07364228 ! adrenal gland development GO:0030325 17 7 0,000 0,02620025 0,07355635 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02620025 0,07347062 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02620025 0,07338509 ! ovulation GO:0030728 9 7 0,000 0,02620025 0,07329976 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02620025 0,07321462 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02620025 0,07312969 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02620025 0,07304495 ! microtubule nucleation GO:0007020 20 7 0,000 0,02620025 0,07296041 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02620025 0,07287606 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02620025 0,07279191 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02620025 0,07270795 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02620025 0,07262418 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02620025 0,07254061 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02620025 0,07245723 ! galactose metabolic process GO:0006012 13 7 0,000 0,02620025 0,07237404 ! vesicle fusion GO:0006906 17 7 0,000 0,02620025 0,07229105 ! response to dietary excess GO:0002021 8 7 0,000 0,02620025 0,07220824 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02620025 0,07212562 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02620025 0,07204319 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02620025 0,07196095 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02620025 0,0718789 ! organ growth GO:0035265 15 7 0,000 0,02620025 0,07179703 ! purine salvage GO:0043101 10 7 0,000 0,02620025 0,07171535 ! nucleoside transport GO:0015858 8 7 0,000 0,02620025 0,07163385 ! parturition GO:0007567 14 7 0,000 0,02620025 0,07155254 ! rRNA modification GO:0000154 14 7 0,000 0,02620025 0,07147142 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02620025 0,07139048 ! spindle checkpoint GO:0031577 15 7 0,000 0,02620025 0,07130972 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02620025 0,07122914 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02620025 0,07114875 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02620025 0,07106854 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02620025 0,0709885 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02620025 0,07090865 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02620025 0,07082898 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02620025 0,07074949 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02620025 0,07067017 ! eating behavior GO:0042755 7 7 0,000 0,02620025 0,07059103 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02620025 0,07051207 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02620025 0,07043329 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02620025 0,07035468 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02620025 0,07027624 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02620025 0,07019799 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02620025 0,0701199 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02620025 0,07004199 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02620025 0,06996425 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02620025 0,06988669 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02620025 0,06980929 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02620025 0,06973207 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02620025 0,06965502 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02620025 0,06957814 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02620025 0,06950142 ! regulation of meiosis GO:0040020 12 7 0,000 0,02620025 0,06942488 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02620025 0,06934851 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02620025 0,0692723 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02620025 0,06919626 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02620025 0,06912039 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02620025 0,06904468 ! transcription termination GO:0006353 13 7 0,000 0,02620025 0,06896914 ! response to tumor cell GO:0002347 13 7 0,000 0,02620025 0,06889376 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02620025 0,06881855 ! anaphase GO:0051322 17 7 0,000 0,02620025 0,0687435 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02620025 0,06866862 ! axonal fasciculation GO:0007413 18 7 0,000 0,02620025 0,0685939 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02620025 0,06851934 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02620025 0,06844494 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02620025 0,06837071 ! diuresis GO:0030146 12 7 0,000 0,02620025 0,06829663 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02620025 0,06822272 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02620025 0,06814896 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02620025 0,06807537 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02620025 0,06800193 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02620025 0,06792865 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02620025 0,06785553 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02620025 0,06778257 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02620025 0,06770977 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02620025 0,06763712 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02620025 0,06756462 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02620025 0,06749228 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02620025 0,0674201 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02620025 0,06734807 ! lymph node development GO:0048535 10 7 0,000 0,02620025 0,06727619 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02620025 0,06720447 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02620025 0,0671329 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02620025 0,06706148 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02620025 0,06699021 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02620025 0,0669191 ! adult feeding behavior GO:0008343 9 7 0,000 0,02620025 0,06684814 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02620025 0,06677732 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02620025 0,06670666 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02620025 0,06663614 ! muscle adaptation GO:0043500 14 7 0,000 0,02620025 0,06656578 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02620025 0,06649556 ! retina homeostasis GO:0001895 12 7 0,000 0,02620025 0,06642549 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02620025 0,06635557 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02620025 0,0662858 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02620025 0,06621617 ! protein prenylation GO:0018342 18 7 0,000 0,02620025 0,06614669 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02620025 0,06607735 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02620025 0,06600816 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02620025 0,06593911 ! lung development GO:0030324 144 67 1,000 0,02676306 0,06728519 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,02676306 0,06721496 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02676306 0,06714487 ! regulation of lipase activity GO:0060191 130 68 1,000 0,027507 0,06893941 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02825922 0,07075096 ! negative regulation of cell size GO:0045792 134 69 1,000 0,02825922 0,07067742 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02825922 0,07060402 ! appendage morphogenesis GO:0035107 135 70 1,000 0,02901965 0,07242872 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,02901965 0,07235367 ! appendage development GO:0048736 136 71 1,000 0,02978824 0,07419307 GO:0060173|limb development, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02988717 0,07436248 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02988717 0,07428566 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02988717 0,074209 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02988717 0,0741325 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02988717 0,07405615 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02988717 0,07397996 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02988717 0,07390393 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02988717 0,07382805 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02988717 0,07375233 ! meiotic prophase I GO:0007128 13 8 0,000 0,02988717 0,07367676 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02988717 0,07360135 ! oligopeptide transport GO:0006857 15 8 0,000 0,02988717 0,0735261 ! UTP metabolic process GO:0046051 8 8 0,000 0,02988717 0,07345099 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02988717 0,07337604 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02988717 0,07330125 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02988717 0,0732266 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02988717 0,07315211 ! succinate metabolic process GO:0006105 14 8 0,000 0,02988717 0,07307777 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02988717 0,07300358 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02988717 0,07292954 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02988717 0,07285565 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02988717 0,0727819 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02988717 0,07270831 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02988717 0,07263487 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02988717 0,07256158 ! reflex GO:0060004 16 8 0,000 0,02988717 0,07248843 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02988717 0,07241543 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02988717 0,07234258 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02988717 0,07226987 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02988717 0,07219731 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02988717 0,0721249 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02988717 0,07205263 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02988717 0,0719805 ! pigment granule organization GO:0048753 16 8 0,000 0,02988717 0,07190852 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02988717 0,07183669 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02988717 0,07176499 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02988717 0,07169344 ! histidine metabolic process GO:0006547 16 8 0,000 0,02988717 0,07162203 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02988717 0,07155077 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02988717 0,07147964 ! glycine catabolic process GO:0006546 13 8 0,000 0,02988717 0,07140866 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02988717 0,07133782 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02988717 0,07126712 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02988717 0,07119656 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02988717 0,07112613 ! melanin metabolic process GO:0006582 15 8 0,000 0,02988717 0,07105585 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02988717 0,07098571 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02988717 0,0709157 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02988717 0,07084583 ! macrophage activation GO:0042116 12 8 0,000 0,02988717 0,0707761 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02988717 0,07070651 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02988717 0,07063706 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02988717 0,07056774 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02988717 0,07049855 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02988717 0,0704295 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02988717 0,07036059 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02988717 0,07029181 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02988717 0,07022317 ! osteoblast development GO:0002076 16 8 0,000 0,02988717 0,07015466 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02988717 0,07008628 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02988717 0,07001804 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02988717 0,06994992 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02988717 0,06988195 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02988717 0,0698141 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02988717 0,06974638 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02988717 0,0696788 ! intermediate filament organization GO:0045109 12 8 0,000 0,02988717 0,06961135 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02988717 0,06954403 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02988717 0,06947683 ! cellular extravasation GO:0045123 12 8 0,000 0,02988717 0,06940977 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02988717 0,06934284 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02988717 0,06927603 ! response to antibiotic GO:0046677 11 8 0,000 0,02988717 0,06920936 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02988717 0,06914281 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02988717 0,06907639 ! DNA topological change GO:0006265 12 8 0,000 0,02988717 0,0690101 ! response to tropane GO:0014073 15 8 0,000 0,02988717 0,06894393 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02988717 0,06887789 ! melanosome transport GO:0032402 13 8 0,000 0,02988717 0,06881198 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02988717 0,0687462 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02988717 0,06868054 ! mast cell activation GO:0045576 14 8 0,000 0,02988717 0,068615 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02988717 0,06854959 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02988717 0,06848431 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02988717 0,06841915 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02988717 0,06835411 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02988717 0,06828919 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02988717 0,0682244 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02988717 0,06815974 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02988717 0,06809519 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02988717 0,06803077 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02988717 0,06796647 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02988717 0,06790229 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02988717 0,06783823 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02988717 0,06777429 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02988717 0,06771047 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02988717 0,06764678 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02988717 0,0675832 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02988717 0,06751974 ! hormone catabolic process GO:0042447 17 8 0,000 0,02988717 0,0674564 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02988717 0,06739318 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02988717 0,06733008 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02988717 0,06726709 ! ATP catabolic process GO:0006200 11 8 0,000 0,02988717 0,06720423 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02988717 0,06714148 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02988717 0,06707885 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02988717 0,06701633 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02988717 0,06695393 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02988717 0,06689165 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02988717 0,06682948 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02988717 0,06676743 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02988717 0,06670549 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02988717 0,06664367 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02988717 0,06658196 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02988717 0,06652037 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02988717 0,06645889 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02988717 0,06639753 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02988717 0,06633628 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02988717 0,06627514 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02988717 0,06621411 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0305649 0,0676533 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0305649 0,06759112 ! carbohydrate transport GO:0008643 110 72 1,000 0,0305649 0,06752905 ! respiratory system development GO:0060541 153 72 1,000 0,0305649 0,0674671 ! learning or memory GO:0007611 147 73 1,000 0,03134956 0,06913568 ! axon guidance GO:0007411 139 73 1,000 0,03134956 0,06907237 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,03214215 0,0707539 ! eye development GO:0001654 143 74 1,000 0,03214215 0,07068922 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0329426 0,07238347 ! axon extension GO:0048675 15 9 0,000 0,03356025 0,07367332 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03356025 0,07360616 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03356025 0,07353913 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03356025 0,07347221 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03356025 0,07340542 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03356025 0,07333875 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03356025 0,0732722 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03356025 0,07320577 ! phosphate transport GO:0006817 19 9 0,000 0,03356025 0,07313946 ! reproductive behavior GO:0019098 19 9 0,000 0,03356025 0,07307327 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03356025 0,0730072 ! CTP metabolic process GO:0046036 9 9 0,000 0,03356025 0,07294125 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03356025 0,07287542 ! GTP metabolic process GO:0046039 9 9 0,000 0,03356025 0,0728097 ! RNA methylation GO:0001510 15 9 0,000 0,03356025 0,07274411 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03356025 0,07267863 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03356025 0,07261327 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03356025 0,07254803 ! artery development GO:0060840 24 9 0,000 0,03356025 0,07248291 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03356025 0,0724179 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03356025 0,07235301 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03356025 0,07228824 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03356025 0,07222358 ! chemosensory behavior GO:0007635 20 9 0,000 0,03356025 0,07215904 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03356025 0,07209461 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03356025 0,07203029 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03356025 0,0719661 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03356025 0,07190201 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03356025 0,07183804 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03356025 0,07177419 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03356025 0,07171044 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03356025 0,07164681 ! protein targeting to ER GO:0045047 22 9 0,000 0,03356025 0,0715833 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03356025 0,07151989 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03356025 0,0714566 ! T cell selection GO:0045058 23 9 0,000 0,03356025 0,07139342 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03356025 0,07133035 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03356025 0,0712674 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03356025 0,07120455 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03356025 0,07114182 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03356025 0,07107919 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03356025 0,07101668 ! mannose metabolic process GO:0006013 13 9 0,000 0,03356025 0,07095427 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03356025 0,07089198 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03356025 0,07082979 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03356025 0,07076771 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03356025 0,07070574 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03356025 0,07064388 ! ruffle organization GO:0031529 15 9 0,000 0,03356025 0,07058213 ! retinol metabolic process GO:0042572 18 9 0,000 0,03356025 0,07052049 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03356025 0,07045895 ! behavioral fear response GO:0001662 22 9 0,000 0,03356025 0,07039752 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03356025 0,0703362 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03356025 0,07027499 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03356025 0,07021388 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,03356025 0,07015288 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03356025 0,07009198 ! segment specification GO:0007379 13 9 0,000 0,03356025 0,07003119 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03356025 0,0699705 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03356025 0,06990992 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03356025 0,06984945 ! response to amine stimulus GO:0014075 13 9 0,000 0,03356025 0,06978908 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03356025 0,06972881 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03356025 0,06966865 ! erythrocyte development GO:0048821 15 9 0,000 0,03356025 0,06960859 ! gas homeostasis GO:0033483 16 9 0,000 0,03356025 0,06954863 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03356025 0,06948878 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03356025 0,06942903 ! renal water homeostasis GO:0003091 14 9 0,000 0,03356025 0,06936938 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03356025 0,06930984 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03356025 0,06925039 ! icosanoid secretion GO:0032309 15 9 0,000 0,03356025 0,06919105 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03356025 0,06913182 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03356025 0,06907268 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03356025 0,06901364 ! regulation of cell division GO:0051302 15 9 0,000 0,03356025 0,06895471 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03356025 0,06889587 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03356025 0,06883714 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03356025 0,0687785 ! sterol catabolic process GO:0016127 11 9 0,000 0,03356025 0,06871997 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03356025 0,06866153 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03356025 0,06860319 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03356025 0,06854496 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03356025 0,06848682 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03356025 0,06842878 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03356025 0,06837084 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03356025 0,068313 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03356025 0,06825525 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03356025 0,0681976 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03356025 0,06814005 ! purine base metabolic process GO:0006144 21 9 0,000 0,03356025 0,0680826 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03356025 0,06802524 ! pigment granule transport GO:0051904 17 9 0,000 0,03356025 0,06796798 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03356025 0,06791082 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03356025 0,06785375 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03356025 0,06779678 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03356025 0,0677399 ! mitochondrion localization GO:0051646 15 9 0,000 0,03356025 0,06768312 ! protein oligomerization GO:0051259 139 78 1,000 0,03539045 0,07131441 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,03622166 0,07292829 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,03622166 0,07286731 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03622166 0,07280643 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,03622166 0,07274566 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,03706038 0,07436804 ! protein import into nucleus GO:0006606 158 80 1,000 0,03706038 0,07430607 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03721955 0,07456306 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03721955 0,07450102 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03721955 0,07443909 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03721955 0,07437727 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03721955 0,07431554 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03721955 0,07425392 ! N-glycan processing GO:0006491 20 10 0,000 0,03721955 0,0741924 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03721955 0,07413099 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03721955 0,07406967 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03721955 0,07400845 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03721955 0,07394734 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03721955 0,07388633 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03721955 0,07382542 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03721955 0,0737646 ! androgen metabolic process GO:0008209 17 10 0,000 0,03721955 0,07370389 ! phospholipid efflux GO:0033700 16 10 0,000 0,03721955 0,07364328 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03721955 0,07358277 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03721955 0,07352236 ! lung alveolus development GO:0048286 26 10 0,000 0,03721955 0,07346204 ! pathogenesis GO:0009405 13 10 0,000 0,03721955 0,07340183 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03721955 0,07334171 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03721955 0,07328169 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03721955 0,07322177 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03721955 0,07316195 ! endoderm development GO:0007492 16 10 0,000 0,03721955 0,07310223 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03721955 0,0730426 ! arginine catabolic process GO:0006527 13 10 0,000 0,03721955 0,07298307 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03721955 0,07292364 ! proline metabolic process GO:0006560 13 10 0,000 0,03721955 0,0728643 ! L-serine metabolic process GO:0006563 18 10 0,000 0,03721955 0,07280507 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03721955 0,07274592 ! V(D)J recombination GO:0033151 28 10 0,000 0,03721955 0,07268688 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03721955 0,07262792 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03721955 0,07256907 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03721955 0,07251031 ! B cell proliferation GO:0042100 18 10 0,000 0,03721955 0,07245164 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03721955 0,07239307 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03721955 0,0723346 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03721955 0,07227621 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03721955 0,07221793 ! epithelial cell development GO:0002064 20 10 0,000 0,03721955 0,07215973 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03721955 0,07210163 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03721955 0,07204363 ! macroautophagy GO:0016236 17 10 0,000 0,03721955 0,07198572 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03721955 0,0719279 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03721955 0,07187017 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03721955 0,07181253 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03721955 0,07175499 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03721955 0,07169754 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03721955 0,07164018 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03721955 0,07158292 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03721955 0,07152574 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03721955 0,07146866 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03721955 0,07141167 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03721955 0,07135477 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03721955 0,07129795 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03721955 0,07124123 ! response to dsRNA GO:0043331 20 10 0,000 0,03721955 0,0711846 ! DNA ligation GO:0006266 19 10 0,000 0,03721955 0,07112806 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03721955 0,07107161 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03721955 0,07101525 ! melanosome localization GO:0032400 16 10 0,000 0,03721955 0,07095898 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03721955 0,0709028 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03721955 0,0708467 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03721955 0,0707907 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03721955 0,07073478 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03721955 0,07067895 ! mRNA cleavage GO:0006379 17 10 0,000 0,03721955 0,07062321 ! protein sumoylation GO:0016925 15 10 0,000 0,03721955 0,07056756 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03721955 0,07051199 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03721955 0,07045651 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03721955 0,07040112 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03721955 0,07034582 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03721955 0,0702906 ! salivary gland development GO:0007431 27 10 0,000 0,03721955 0,07023547 ! prophase GO:0051324 15 10 0,000 0,03721955 0,07018043 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03721955 0,07012547 ! apical protein localization GO:0045176 15 10 0,000 0,03721955 0,0700706 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03721955 0,07001582 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03721955 0,06996112 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03721955 0,0699065 ! midbrain development GO:0030901 13 10 0,000 0,03721955 0,06985197 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03721955 0,06979753 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03721955 0,06974317 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03721955 0,0696889 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03721955 0,0696347 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03721955 0,0695806 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03721955 0,06952658 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03721955 0,06947264 ! detection of calcium ion GO:0005513 23 10 0,000 0,03721955 0,06941878 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03721955 0,06936501 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03721955 0,06931132 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03721955 0,06925772 ! activation of innate immune response GO:0002218 12 10 0,000 0,03721955 0,0692042 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03721955 0,06915076 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03721955 0,0690974 ! response to nicotine GO:0035094 20 10 0,000 0,03721955 0,06904413 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03721955 0,06899093 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03721955 0,06893782 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03721955 0,06888479 ! localization within membrane GO:0051668 20 10 0,000 0,03721955 0,06883184 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03790656 0,07004853 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,03790656 0,06999477 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,03876012 0,07151599 ! response to nutrient GO:0007584 125 82 1,000 0,03876012 0,07146119 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,03876012 0,07140647 ! regulation of lyase activity GO:0051339 160 83 1,000 0,039621 0,07293658 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,04048912 0,07447769 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,04048912 0,0744208 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04086511 0,07505455 ! respiratory burst GO:0045730 17 11 0,000 0,04086511 0,0749973 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04086511 0,07494013 ! neuron fate specification GO:0048665 17 11 0,000 0,04086511 0,07488306 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04086511 0,07482607 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04086511 0,07476917 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04086511 0,07471235 ! thyroid gland development GO:0030878 26 11 0,000 0,04086511 0,07465562 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04086511 0,07459898 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04086511 0,07454242 ! response to pain GO:0048265 24 11 0,000 0,04086511 0,07448595 ! T cell proliferation GO:0042098 26 11 0,000 0,04086511 0,07442957 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04086511 0,07437326 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04086511 0,07431705 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04086511 0,07426092 ! bone resorption GO:0045453 16 11 0,000 0,04086511 0,07420487 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04086511 0,07414891 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04086511 0,07409303 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04086511 0,07403724 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04086511 0,07398153 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04086511 0,07392591 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04086511 0,07387036 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04086511 0,07381491 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04086511 0,07375953 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04086511 0,07370424 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04086511 0,07364903 ! lipid digestion GO:0044241 18 11 0,000 0,04086511 0,0735939 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04086511 0,07353886 ! UV protection GO:0009650 19 11 0,000 0,04086511 0,0734839 ! adult heart development GO:0007512 14 11 0,000 0,04086511 0,07342902 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04086511 0,07337422 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04086511 0,0733195 ! temperature homeostasis GO:0001659 17 11 0,000 0,04086511 0,07326487 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04086511 0,07321032 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04086511 0,07315584 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04086511 0,07310145 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04086511 0,07304714 ! regulation of organ growth GO:0046620 13 11 0,000 0,04086511 0,07299291 ! pigment granule localization GO:0051875 20 11 0,000 0,04086511 0,07293877 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04086511 0,0728847 ! vasoconstriction GO:0042310 18 11 0,000 0,04086511 0,07283071 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04086511 0,0727768 ! embryonic axis specification GO:0000578 18 11 0,000 0,04086511 0,07272297 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04086511 0,07266922 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04086511 0,07261555 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04086511 0,07256196 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04086511 0,07250845 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04086511 0,07245502 ! zymogen activation GO:0031638 15 11 0,000 0,04086511 0,07240166 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04086511 0,07234839 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04086511 0,07229519 ! nucleosome positioning GO:0016584 15 11 0,000 0,04086511 0,07224207 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04086511 0,07218903 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04086511 0,07213606 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04086511 0,07208318 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04086511 0,07203037 ! acid secretion GO:0046717 18 11 0,000 0,04086511 0,07197764 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04086511 0,07192499 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04086511 0,07187241 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04086511 0,07181991 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04086511 0,07176749 ! cholesterol efflux GO:0033344 19 11 0,000 0,04086511 0,07171514 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04086511 0,07166287 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04086511 0,07161067 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04086511 0,07155856 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04086511 0,07150651 ! embryonic gut development GO:0048566 15 11 0,000 0,04086511 0,07145455 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04086511 0,07140265 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04086511 0,07135084 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04086511 0,0712991 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04086511 0,07124743 ! defense response to fungus GO:0050832 13 11 0,000 0,04086511 0,07119584 ! developmental induction GO:0031128 19 11 0,000 0,04086511 0,07114432 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04086511 0,07109288 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04086511 0,07104151 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04086511 0,07099022 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04086511 0,070939 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04086511 0,07088786 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04086511 0,07083678 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,04136443 0,07165069 ! tube morphogenesis GO:0035239 176 86 1,000 0,04224685 0,07312657 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,04313633 0,07461251 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,04313633 0,07455891 ! cellular respiration GO:0045333 135 88 1,000 0,04403279 0,07605377 ! regulation of neurological system process GO:0031644 148 88 1,000 0,04403279 0,07599921 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04449699 0,07674535 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04449699 0,07669037 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04449699 0,07663547 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04449699 0,07658066 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04449699 0,07652592 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04449699 0,07647126 ! cartilage condensation GO:0001502 20 12 0,000 0,04449699 0,07641667 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04449699 0,07636217 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04449699 0,07630774 ! protein complex disassembly GO:0043241 27 12 0,000 0,04449699 0,07625339 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,04449699 0,07619912 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04449699 0,07614492 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04449699 0,0760908 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04449699 0,07603676 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04449699 0,0759828 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04449699 0,07592891 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04449699 0,07587509 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04449699 0,07582136 ! drug transport GO:0015893 16 12 0,000 0,04449699 0,0757677 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04449699 0,07571411 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04449699 0,07566061 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04449699 0,07560717 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04449699 0,07555382 ! focal adhesion formation GO:0048041 35 12 0,000 0,04449699 0,07550053 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04449699 0,07544733 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04449699 0,0753942 ! forebrain cell migration GO:0021885 21 12 0,000 0,04449699 0,07534114 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04449699 0,07528816 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04449699 0,07523525 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04449699 0,07518241 ! fear response GO:0042596 26 12 0,000 0,04449699 0,07512966 ! monoamine transport GO:0015844 18 12 0,000 0,04449699 0,07507697 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04449699 0,07502436 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04449699 0,07497182 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04449699 0,07491936 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04449699 0,07486696 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04449699 0,07481465 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04449699 0,0747624 ! protein homotetramerization GO:0051289 21 12 0,000 0,04449699 0,07471023 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04449699 0,07465813 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04449699 0,0746061 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04449699 0,07455415 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04449699 0,07450227 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04449699 0,07445046 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04449699 0,07439872 ! cranial nerve development GO:0021545 20 12 0,000 0,04449699 0,07434705 ! fucose catabolic process GO:0019317 22 12 0,000 0,04449699 0,07429546 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,04449699 0,07424394 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04449699 0,07419249 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04449699 0,07414111 ! gland morphogenesis GO:0022612 29 12 0,000 0,04449699 0,0740898 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04449699 0,07403856 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04449699 0,07398739 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04449699 0,0739363 ! spleen development GO:0048536 22 12 0,000 0,04449699 0,07388527 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04449699 0,07383432 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04449699 0,07378343 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04449699 0,07373262 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04449699 0,07368187 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04449699 0,0736312 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04449699 0,07358059 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04449699 0,07353005 ! response to cold GO:0009409 17 12 0,000 0,04449699 0,07347959 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04449699 0,07342919 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04449699 0,07337886 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04493618 0,07405236 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,04584642 0,07550068 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04811524 0,07918281 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04811524 0,07912868 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04811524 0,07907463 ! peroxisomal transport GO:0043574 24 13 0,000 0,04811524 0,07902066 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04811524 0,07896675 ! lipid localization GO:0010876 28 13 0,000 0,04811524 0,07891293 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04811524 0,07885917 ! organelle fusion GO:0048284 32 13 0,000 0,04811524 0,07880549 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04811524 0,07875188 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04811524 0,07869834 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04811524 0,07864488 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04811524 0,07859149 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04811524 0,07853817 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04811524 0,07848492 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04811524 0,07843175 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04811524 0,07837865 ! methionine metabolic process GO:0006555 27 13 0,000 0,04811524 0,07832562 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04811524 0,07827266 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04811524 0,07821977 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04811524 0,07816696 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04811524 0,07811421 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04811524 0,07806154 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04811524 0,07800894 ! exocrine system development GO:0035272 32 13 0,000 0,04811524 0,07795641 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04811524 0,07790394 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04811524 0,07785155 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04811524 0,07779924 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04811524 0,07774699 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04811524 0,07769481 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04811524 0,0776427 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04811524 0,07759066 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04811524 0,07753869 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04811524 0,07748679 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04811524 0,07743496 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04811524 0,0773832 ! ribosome assembly GO:0042255 17 13 0,000 0,04811524 0,0773315 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04811524 0,07727988 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04811524 0,07722833 ! chromatin silencing GO:0006342 26 13 0,000 0,04811524 0,07717684 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04811524 0,07712542 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04811524 0,07707408 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04811524 0,0770228 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04811524 0,07697158 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04811524 0,07692044 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04811524 0,07686936 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04811524 0,07681836 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04811524 0,07676742 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04811524 0,07671654 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04811524 0,07666574 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04811524 0,076615 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04811524 0,07656433 ! insulin secretion GO:0030073 23 13 0,000 0,04811524 0,07651372 ! actin filament polymerization GO:0030041 24 13 0,000 0,04811524 0,07646319 ! acrosome reaction GO:0007340 18 13 0,000 0,04811524 0,07641271 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,04861766 0,07715969 ! regulation of membrane potential GO:0042391 164 93 1,000 0,04861766 0,07710883 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04861766 0,07705803 ! female pregnancy GO:0007565 164 94 1,000 0,0495547 0,07849152 ! transcription initiation GO:0006352 153 94 1,000 0,0495547 0,07843988 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0495547 0,07838831 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,05049829 0,07982843 ! detection of stimulus GO:0051606 151 96 1,000 0,05144835 0,08127691 ! rRNA transcription GO:0009303 25 14 0,000 0,0517199 0,08165229 ! lactation GO:0007595 26 14 0,000 0,0517199 0,08159875 ! reproductive cellular process GO:0048610 20 14 0,000 0,0517199 0,08154527 ! tRNA modification GO:0006400 20 14 0,000 0,0517199 0,08149187 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0517199 0,08143854 ! water transport GO:0006833 21 14 0,000 0,0517199 0,08138528 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0517199 0,08133208 ! non-recombinational repair GO:0000726 25 14 0,000 0,0517199 0,08127896 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0517199 0,08122591 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0517199 0,08117292 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0517199 0,08112001 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0517199 0,08106716 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0517199 0,08101438 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0517199 0,08096167 ! palate development GO:0060021 31 14 0,000 0,0517199 0,08090903 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0517199 0,08085646 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0517199 0,08080395 ! arginine metabolic process GO:0006525 17 14 0,000 0,0517199 0,08075152 ! regulation of heart rate GO:0002027 24 14 0,000 0,0517199 0,08069915 ! organic alcohol transport GO:0015850 29 14 0,000 0,0517199 0,08064685 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0517199 0,08059462 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0517199 0,08054245 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0517199 0,08049035 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0517199 0,08043832 ! L-amino acid transport GO:0015807 30 14 0,000 0,0517199 0,08038636 ! bone mineralization GO:0030282 17 14 0,000 0,0517199 0,08033447 ! stem cell development GO:0048864 43 14 0,000 0,0517199 0,08028264 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0517199 0,08023088 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0517199 0,08017918 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0517199 0,08012755 ! cerebellum development GO:0021549 21 14 0,000 0,0517199 0,08007599 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0517199 0,08002449 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0517199 0,07997306 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0517199 0,0799217 ! cofactor transport GO:0051181 26 14 0,000 0,0517199 0,0798704 ! NADP metabolic process GO:0006739 24 14 0,000 0,0517199 0,07981917 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0517199 0,07976801 ! intestinal absorption GO:0050892 25 14 0,000 0,0517199 0,0797169 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0517199 0,07966587 ! oxygen transport GO:0015671 21 14 0,000 0,0517199 0,0796149 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0517199 0,079564 ! male genitalia development GO:0030539 24 14 0,000 0,0517199 0,07951316 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0517199 0,07946238 ! regulation of axon extension GO:0030516 37 14 0,000 0,0517199 0,07941167 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0517199 0,07936103 ! response to virus GO:0009615 160 98 1,000 0,05336767 0,08183723 ! interphase GO:0051325 213 98 1,000 0,05336767 0,08178511 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,05433681 0,08321729 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05531104 0,08465544 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05531104 0,08460163 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05531104 0,08454788 ! superoxide anion generation GO:0042554 20 15 0,000 0,05531104 0,0844942 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05531104 0,08444058 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05531104 0,08438704 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05531104 0,08433356 ! copper ion transport GO:0006825 20 15 0,000 0,05531104 0,08428015 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05531104 0,08422681 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05531104 0,08417353 ! sulfate transport GO:0008272 23 15 0,000 0,05531104 0,08412033 ! response to cAMP GO:0051591 22 15 0,000 0,05531104 0,08406719 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05531104 0,08401412 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05531104 0,08396111 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05531104 0,08390817 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05531104 0,0838553 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05531104 0,08380249 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05531104 0,08374975 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05531104 0,08369708 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05531104 0,08364447 ! pituitary gland development GO:0021983 29 15 0,000 0,05531104 0,08359193 ! vesicle coating GO:0006901 33 15 0,000 0,05531104 0,08353946 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05531104 0,08348705 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05531104 0,08343471 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,05531104 0,08338243 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05531104 0,08333022 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,05531104 0,08327807 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05531104 0,08322599 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05531104 0,08317397 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05531104 0,08312202 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05531104 0,08307014 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05531104 0,08301831 ! histone deacetylation GO:0016575 20 15 0,000 0,05531104 0,08296656 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05531104 0,08291487 ! tissue regeneration GO:0042246 26 15 0,000 0,05531104 0,08286324 ! water homeostasis GO:0030104 27 15 0,000 0,05531104 0,08281167 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05531104 0,08276017 ! muscle maintenance GO:0046716 26 15 0,000 0,05531104 0,08270874 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05531104 0,08265737 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05531104 0,08260606 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05531104 0,08255481 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05531104 0,08250363 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05531104 0,08245251 ! cell killing GO:0001906 29 15 0,000 0,05531104 0,08240146 ! detection of bacterium GO:0016045 18 15 0,000 0,05531104 0,08235047 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,05531104 0,08229954 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05531104 0,08224868 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05531104 0,08219787 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05531104 0,08214714 ! peptide hormone processing GO:0016486 23 15 0,000 0,05531104 0,08209646 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05888869 0,08735277 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05888869 0,08729895 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05888869 0,08724519 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05888869 0,0871915 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05888869 0,08713788 ! bone remodeling GO:0046849 27 16 0,000 0,05888869 0,08708432 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05888869 0,08703083 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05888869 0,08697741 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05888869 0,08692405 ! startle response GO:0001964 28 16 0,000 0,05888869 0,08687075 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05888869 0,08681752 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05888869 0,08676436 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05888869 0,08671126 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05888869 0,08665822 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05888869 0,08660525 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05888869 0,08655235 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05888869 0,08649951 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05888869 0,08644673 ! response to osmotic stress GO:0006970 25 16 0,000 0,05888869 0,08639402 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05888869 0,08634137 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05888869 0,08628879 ! fructose metabolic process GO:0006000 25 16 0,000 0,05888869 0,08623627 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05888869 0,08618382 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05888869 0,08613143 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05888869 0,0860791 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05888869 0,08602683 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05888869 0,08597463 ! axon cargo transport GO:0008088 43 16 0,000 0,05888869 0,0859225 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05888869 0,08587042 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05888869 0,08581841 ! DNA replication initiation GO:0006270 27 16 0,000 0,05888869 0,08576646 ! neuron recognition GO:0008038 35 16 0,000 0,05888869 0,08571458 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05888869 0,08566275 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05888869 0,08561099 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05888869 0,0855593 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05888869 0,08550766 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05888869 0,08545609 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05888869 0,08540458 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05888869 0,08535313 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05888869 0,08530174 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05888869 0,08525042 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05888869 0,08519915 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05888869 0,08514795 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05888869 0,08509681 ! defense response to virus GO:0051607 37 16 0,000 0,05888869 0,08504573 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06245292 0,090139 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06245292 0,09008496 ! metencephalon development GO:0022037 30 17 0,000 0,06245292 0,09003099 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06245292 0,08997708 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06245292 0,08992323 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06245292 0,08986945 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06245292 0,08981573 ! endothelial cell migration GO:0043542 28 17 0,000 0,06245292 0,08976208 ! inositol metabolic process GO:0006020 28 17 0,000 0,06245292 0,08970849 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06245292 0,08965496 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06245292 0,0896015 ! glial cell development GO:0021782 27 17 0,000 0,06245292 0,0895481 ! limbic system development GO:0021761 36 17 0,000 0,06245292 0,08949477 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06245292 0,0894415 ! adult walking behavior GO:0007628 33 17 0,000 0,06245292 0,08938829 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06245292 0,08933515 ! heart looping GO:0001947 30 17 0,000 0,06245292 0,08928207 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06245292 0,08922905 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06245292 0,08917609 ! myoblast differentiation GO:0045445 45 17 0,000 0,06245292 0,0891232 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06245292 0,08907037 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06245292 0,0890176 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06245292 0,0889649 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06245292 0,08891226 ! glycine metabolic process GO:0006544 28 17 0,000 0,06245292 0,08885968 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06245292 0,08880716 ! NAD metabolic process GO:0019674 29 17 0,000 0,06245292 0,08875471 ! membrane budding GO:0006900 37 17 0,000 0,06245292 0,08870231 ! DNA integration GO:0015074 29 17 0,000 0,06245292 0,08864998 ! regulation of protein binding GO:0043393 33 17 0,000 0,06245292 0,08859771 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06245292 0,0885455 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06245292 0,08849335 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06245292 0,08844127 ! genitalia development GO:0048806 30 17 0,000 0,06245292 0,08838924 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06245292 0,08833728 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06245292 0,08828538 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06245292 0,08823354 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06245292 0,08818176 ! steroid catabolic process GO:0006706 31 17 0,000 0,06245292 0,08813004 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06245292 0,08807838 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06245292 0,08802678 ! gas transport GO:0015669 25 17 0,000 0,06245292 0,08797524 ! organic cation transport GO:0015695 31 17 0,000 0,06245292 0,08792377 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06245292 0,08787235 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06245292 0,08782099 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06245292 0,08776969 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06245292 0,08771846 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06245292 0,08766728 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06600376 0,09259769 ! neuron maturation GO:0042551 42 18 0,000 0,06600376 0,09254373 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06600376 0,09248983 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06600376 0,092436 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06600376 0,09238222 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06600376 0,09232851 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06600376 0,09227487 ! memory GO:0007613 31 18 0,000 0,06600376 0,09222128 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06600376 0,09216776 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06600376 0,09211429 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06600376 0,09206089 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06600376 0,09200756 GO:0042744|hydrogen peroxide catabolic process, ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06600376 0,09195428 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06600376 0,09190107 ! response to retinoic acid GO:0032526 26 18 0,000 0,06600376 0,09184791 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06600376 0,09179482 ! response to fungus GO:0009620 21 18 0,000 0,06600376 0,09174179 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06600376 0,09168882 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06600376 0,09163592 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06600376 0,09158307 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06600376 0,09153028 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06600376 0,09147756 ! vitamin transport GO:0051180 27 18 0,000 0,06600376 0,0914249 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06600376 0,09137229 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06600376 0,09131975 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06600376 0,09126727 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06600376 0,09121484 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06600376 0,09116248 ! nerve development GO:0021675 28 18 0,000 0,06600376 0,09111018 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06600376 0,09105794 ! protein secretion GO:0009306 39 19 0,000 0,06954127 0,09588326 ! positive regulation of translation GO:0045727 30 19 0,000 0,06954127 0,09582835 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06954127 0,0957735 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06954127 0,09571871 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06954127 0,09566398 ! skin development GO:0043588 36 19 0,000 0,06954127 0,09560931 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06954127 0,09555471 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06954127 0,09550017 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06954127 0,09544569 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06954127 0,09539128 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06954127 0,09533692 ! cerebral cortex development GO:0021987 36 19 0,000 0,06954127 0,09528263 ! pigmentation during development GO:0048066 41 19 0,000 0,06954127 0,0952284 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06954127 0,09517423 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,06954127 0,09512012 ! heme metabolic process GO:0042168 36 19 0,000 0,06954127 0,09506608 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06954127 0,09501209 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06954127 0,09495817 ! plasma membrane fusion GO:0045026 28 19 0,000 0,06954127 0,09490431 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,06954127 0,09485051 ! peptide cross-linking GO:0018149 37 19 0,000 0,06954127 0,09479677 ! protein export from nucleus GO:0006611 36 19 0,000 0,06954127 0,09474309 ! heart process GO:0003015 30 19 0,000 0,06954127 0,09468947 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06954127 0,09463591 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06954127 0,09458242 ! visual learning GO:0008542 36 19 0,000 0,06954127 0,09452898 ! cellular pigmentation GO:0033059 36 19 0,000 0,06954127 0,09447561 ! G1 phase GO:0051318 40 19 0,000 0,06954127 0,09442229 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06954127 0,09436903 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06954127 0,09431584 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06954127 0,0942627 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06954127 0,09420963 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06954127 0,09415661 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06954127 0,09410365 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06954127 0,09405076 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06954127 0,09399792 ! cilium assembly GO:0042384 37 19 0,000 0,06954127 0,09394514 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06954127 0,09389242 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0730655 0,0985954 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0730655 0,09854013 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0730655 0,09848493 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0730655 0,09842979 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0730655 0,0983747 ! response to vitamin GO:0033273 31 20 0,000 0,0730655 0,09831968 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0730655 0,09826473 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0730655 0,09820983 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0730655 0,098155 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0730655 0,09810022 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0730655 0,09804551 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0730655 0,09799086 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0730655 0,09793627 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0730655 0,09788174 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0730655 0,09782727 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0730655 0,09777286 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0730655 0,09771851 ! body fluid secretion GO:0007589 31 20 0,000 0,0730655 0,09766422 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0730655 0,09760999 ! peptide secretion GO:0002790 35 20 0,000 0,0730655 0,09755582 ! stem cell differentiation GO:0048863 53 20 0,000 0,0730655 0,09750172 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0730655 0,09744767 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0730655 0,09739368 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0730655 0,09733975 ! sensory perception of pain GO:0019233 30 20 0,000 0,0730655 0,09728589 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0730655 0,09723208 ! diencephalon development GO:0021536 34 20 0,000 0,0730655 0,09717833 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0730655 0,09712464 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0730655 0,09707101 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0730655 0,09701744 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0730655 0,09696393 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0730655 0,09691047 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0730655 0,09685708 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0730655 0,09680374 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0730655 0,09675047 ! regulation of glucose import GO:0046324 29 20 0,000 0,0730655 0,09669725 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0730655 0,09664409 ! actin filament-based movement GO:0030048 43 20 0,000 0,0730655 0,09659099 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0730655 0,09653794 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0730655 0,09648496 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0730655 0,09643203 ! regulation of cell killing GO:0031341 42 21 0,000 0,0765765 0,10101045 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0765765 0,1009551 ! hormone secretion GO:0046879 38 21 0,000 0,0765765 0,10089981 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0765765 0,10084459 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0765765 0,10078942 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0765765 0,10073431 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0765765 0,10067927 ! axis specification GO:0009798 38 21 0,000 0,0765765 0,10062428 ! ovarian follicle development GO:0001541 35 21 0,000 0,0765765 0,10056936 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0765765 0,10051449 ! smooth muscle contraction GO:0006939 46 21 0,000 0,0765765 0,10045968 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0765765 0,10040494 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0765765 0,10035025 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0765765 0,10029562 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0765765 0,10024106 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0765765 0,10018655 ! cytolysis GO:0019835 24 21 0,000 0,0765765 0,1001321 ! vasodilation GO:0042311 39 21 0,000 0,0765765 0,10007771 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0765765 0,10002338 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,0765765 0,0999691 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,0765765 0,09991489 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0765765 0,09986074 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0765765 0,09980664 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0765765 0,0997526 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,0765765 0,09969863 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0765765 0,09964471 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0765765 0,09959084 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0765765 0,09953704 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0765765 0,09948329 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0765765 0,09942961 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0765765 0,09937598 ! collagen catabolic process GO:0030574 28 21 0,000 0,0765765 0,0993224 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0765765 0,09926889 ! gut development GO:0048565 39 21 0,000 0,0765765 0,09921543 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08007432 0,1036915 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08007432 0,10363572 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08007432 0,10358 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08007432 0,10352434 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08007432 0,10346875 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08007432 0,10341321 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08007432 0,10335773 ! regeneration GO:0031099 41 22 0,000 0,08007432 0,10330231 ! keratinization GO:0031424 28 22 0,000 0,08007432 0,10324695 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08007432 0,10319165 ! sensory perception of taste GO:0050909 28 22 0,000 0,08007432 0,10313641 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08007432 0,10308122 ! vacuolar transport GO:0007034 36 22 0,000 0,08007432 0,1030261 ! lysosome organization GO:0007040 41 22 0,000 0,08007432 0,10297103 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08007432 0,10291603 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08007432 0,10286108 ! fucose metabolic process GO:0006004 39 22 0,000 0,08007432 0,10280619 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08007432 0,10275136 ! ureteric bud development GO:0001657 43 22 0,000 0,08007432 0,10269659 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08007432 0,10264188 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08007432 0,10258722 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08007432 0,10253263 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08007432 0,10247809 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08007432 0,10242361 ! sarcomere organization GO:0045214 30 22 0,000 0,08007432 0,10236918 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,08007432 0,10231482 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08007432 0,10226051 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08007432 0,10220626 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08007432 0,10215207 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08007432 0,10209794 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,083559 0,10648461 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,083559 0,10642824 ! viral genome replication GO:0019079 41 23 0,000 0,083559 0,10637193 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,083559 0,10631568 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,083559 0,10625949 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,083559 0,10620336 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,083559 0,10614728 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,083559 0,10609127 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,083559 0,10603531 ! visual behavior GO:0007632 42 23 0,000 0,083559 0,10597942 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,083559 0,10592358 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,083559 0,1058678 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,083559 0,10581208 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,083559 0,10575642 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,083559 0,10570082 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,083559 0,10564527 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,083559 0,10558979 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,083559 0,10553436 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,083559 0,10547899 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,083559 0,10542368 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,083559 0,10536842 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,083559 0,10531323 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,083559 0,10525809 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,083559 0,10520301 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,083559 0,10514799 ! fatty acid transport GO:0015908 44 23 0,000 0,083559 0,10509302 ! platelet activation GO:0030168 37 23 0,000 0,083559 0,10503812 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,083559 0,10498326 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,083559 0,10492847 ! hormone transport GO:0009914 40 23 0,000 0,083559 0,10487374 ! cell-cell recognition GO:0009988 25 23 0,000 0,083559 0,10481906 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,083559 0,10476444 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,083559 0,10470987 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,083559 0,10465536 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,083559 0,10460091 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,0870306 0,10889008 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0870306 0,10883348 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0870306 0,10877694 ! vesicle docking GO:0048278 47 24 0,000 0,0870306 0,10872047 ! spinal cord development GO:0021510 47 24 0,000 0,0870306 0,10866405 ! vacuole organization GO:0007033 43 24 0,000 0,0870306 0,10860769 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0870306 0,10855138 ! digestive system process GO:0022600 39 24 0,000 0,0870306 0,10849514 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0870306 0,10843895 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0870306 0,10838282 ! regulation of behavior GO:0050795 43 24 0,000 0,0870306 0,10832676 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0870306 0,10827074 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0870306 0,10821479 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0870306 0,10815889 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0870306 0,10810305 ! membrane depolarization GO:0051899 39 24 0,000 0,0870306 0,10804727 ! pallium development GO:0021543 49 24 0,000 0,0870306 0,10799155 ! pentose metabolic process GO:0019321 35 24 0,000 0,0870306 0,10793589 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0870306 0,10788028 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0870306 0,10782473 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0870306 0,10776923 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0870306 0,10771379 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0870306 0,10765842 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0870306 0,10760309 ! regulation of amine transport GO:0051952 40 24 0,000 0,0870306 0,10754783 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,09048916 0,11176433 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,09048916 0,11170699 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09048916 0,1116497 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,09048916 0,11159247 ! phototransduction GO:0007602 33 25 0,000 0,09048916 0,11153531 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09048916 0,1114782 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,09048916 0,11142115 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09048916 0,11136415 ! chromosome condensation GO:0030261 45 25 0,000 0,09048916 0,11130722 ! response to starvation GO:0042594 42 25 0,000 0,09048916 0,11125034 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09048916 0,11119352 ! neural crest cell development GO:0014032 54 25 0,000 0,09048916 0,11113676 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09048916 0,11108006 ! negative regulation of cell development GO:0010721 73 25 0,000 0,09048916 0,11102342 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09048916 0,11096683 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09048916 0,1109103 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09048916 0,11085383 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09048916 0,11079741 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09048916 0,11074106 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09048916 0,11068476 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09048916 0,11062852 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,09048916 0,11057233 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09048916 0,1105162 ! telomere organization GO:0032200 43 25 0,000 0,09048916 0,11046013 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09048916 0,11040412 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09048916 0,11034816 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09393473 0,11449188 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09393473 0,11443391 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09393473 0,114376 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09393473 0,11431814 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09393473 0,11426035 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09393473 0,11420261 ! tube lumen formation GO:0035148 50 26 0,000 0,09393473 0,11414493 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09393473 0,11408731 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09393473 0,11402975 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,09393473 0,11397225 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09393473 0,1139148 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09393473 0,11385742 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09393473 0,11380009 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09393473 0,11374281 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09393473 0,1136856 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09393473 0,11362844 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09393473 0,11357134 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09393473 0,1135143 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,09736737 0,11760336 ! neuron fate commitment GO:0048663 48 27 0,000 0,09736737 0,11754435 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,09736737 0,1174854 ! iron ion transport GO:0006826 59 27 0,000 0,09736737 0,11742651 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09736737 0,11736768 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09736737 0,11730891 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09736737 0,1172502 ! fat cell differentiation GO:0045444 50 27 0,000 0,09736737 0,11719154 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09736737 0,11713295 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,09736737 0,11707441 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09736737 0,11701593 ! autophagy GO:0006914 41 27 0,000 0,09736737 0,11695751 ! response to toxin GO:0009636 47 27 0,000 0,09736737 0,11689915 ! primary neural tube formation GO:0014020 51 27 0,000 0,09736737 0,11684084 ! base-excision repair GO:0006284 41 27 0,000 0,09736737 0,1167826 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09736737 0,11672441 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09736737 0,11666628 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09736737 0,11660821 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09736737 0,1165502 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,09736737 0,11649224 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09736737 0,11643434 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10078711 0,12046388 ! circadian rhythm GO:0007623 50 28 0,000 0,10078711 0,12040407 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10078711 0,12034432 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10078711 0,12028462 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10078711 0,12022499 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10078711 0,12016541 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10078711 0,12010589 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10078711 0,12004643 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10078711 0,11998704 ! synaptogenesis GO:0007416 42 28 0,000 0,10078711 0,11992769 ! lipid oxidation GO:0034440 43 28 0,000 0,10078711 0,11986841 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10078711 0,11980919 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10078711 0,11975002 ! translational initiation GO:0006413 65 29 0,000 0,10419402 0,12373682 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10419402 0,12367578 ! regulation of pH GO:0006885 43 29 0,000 0,10419402 0,12361479 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10419402 0,12355387 ! catechol metabolic process GO:0009712 54 29 0,000 0,10419402 0,12349301 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10419402 0,1234322 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10419402 0,12337146 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10419402 0,12331077 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10419402 0,12325015 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10419402 0,12318958 ! cell fate determination GO:0001709 60 29 0,000 0,10419402 0,12312908 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10419402 0,12306863 ! detection of light stimulus GO:0009583 38 29 0,000 0,10419402 0,12300825 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,10419402 0,12294792 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,10419402 0,12288765 ! phenol metabolic process GO:0018958 55 30 0,000 0,10758812 0,12682853 ! zinc ion transport GO:0006829 45 30 0,000 0,10758812 0,12676642 ! membrane docking GO:0022406 61 30 0,000 0,10758812 0,12670437 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10758812 0,12664238 ! cell junction assembly GO:0034329 78 30 0,000 0,10758812 0,12658045 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10758812 0,12651858 ! acute-phase response GO:0006953 49 30 0,000 0,10758812 0,12645678 ! myofibril assembly GO:0030239 47 30 0,000 0,10758812 0,12639503 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10758812 0,12633335 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10758812 0,12627172 ! phospholipid transport GO:0015914 51 30 0,000 0,10758812 0,12621015 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10758812 0,12614865 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10758812 0,1260872 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10758812 0,12602582 ! eye morphogenesis GO:0048592 60 30 0,000 0,10758812 0,12596449 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10758812 0,12590322 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11096948 0,12979707 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,11096948 0,129734 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11096948 0,12967099 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11096948 0,12960805 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,11096948 0,12954516 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11096948 0,12948234 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11096948 0,12941957 ! ovulation cycle process GO:0022602 49 31 0,000 0,11096948 0,12935687 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11096948 0,12929423 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11096948 0,12923164 ! peptide transport GO:0015833 55 31 0,000 0,11096948 0,12916912 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11096948 0,12910666 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11096948 0,12904426 ! mesoderm formation GO:0001707 69 31 0,000 0,11096948 0,12898192 ! natural killer cell activation GO:0030101 45 31 0,000 0,11096948 0,12891964 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11096948 0,12885742 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11096948 0,12879526 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11096948 0,12873316 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11096948 0,12867112 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11433814 0,13251328 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11433814 0,13244948 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11433814 0,13238574 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11433814 0,13232206 ! cholesterol transport GO:0030301 56 32 0,000 0,11433814 0,13225845 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11433814 0,13219489 ! spliceosome assembly GO:0000245 67 32 0,000 0,11433814 0,1321314 ! spindle organization GO:0007051 46 32 0,000 0,11433814 0,13206796 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11433814 0,13200459 ! metanephros development GO:0001656 74 32 0,000 0,11433814 0,13194128 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11433814 0,13187803 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11433814 0,13181484 ! muscle cell development GO:0055001 49 32 0,000 0,11433814 0,13175171 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11433814 0,13168864 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11433814 0,13162563 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11433814 0,13156268 ! ovulation cycle GO:0042698 51 32 0,000 0,11433814 0,13149979 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11433814 0,13143697 ! hindbrain development GO:0030902 61 32 0,000 0,11433814 0,1313742 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11433814 0,13131149 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11433814 0,13124884 ! gene silencing GO:0016458 65 32 0,000 0,11433814 0,13118625 ! post-embryonic development GO:0009791 69 33 0,000 0,11769415 0,13497241 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,11769415 0,13490811 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11769415 0,13484387 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11769415 0,13477969 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11769415 0,13471557 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11769415 0,13465151 ! cell fate specification GO:0001708 52 33 0,000 0,11769415 0,13458751 ! sterol transport GO:0015918 57 33 0,000 0,11769415 0,13452357 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,11769415 0,1344597 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11769415 0,13439588 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11769415 0,13433213 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11769415 0,13426843 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,12103755 0,13801722 ! glial cell differentiation GO:0010001 63 34 0,000 0,12103755 0,13795184 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12103755 0,13788653 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,12103755 0,13782127 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,12103755 0,13775607 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,12103755 0,13769094 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,12103755 0,13762587 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12103755 0,13756086 ! spermatid development GO:0007286 63 34 0,000 0,12103755 0,13749591 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12103755 0,13743103 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12103755 0,1373662 ! regulation of muscle development GO:0048634 70 35 0,000 0,12436839 0,14107984 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,12436839 0,14101336 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12436839 0,14094694 ! odontogenesis GO:0042476 66 35 0,000 0,12436839 0,14088058 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,12436839 0,14081428 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,12436839 0,14074805 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,12436839 0,14068188 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,12436839 0,14061577 ! cytokine production GO:0001816 59 35 0,000 0,12436839 0,14054972 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,12436839 0,14048373 ! neural tube formation GO:0001841 67 35 0,000 0,12436839 0,14041781 ! vesicle localization GO:0051648 64 35 0,000 0,12436839 0,14035195 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12768672 0,14402918 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,12768672 0,14396169 ! cell junction organization GO:0034330 86 36 0,000 0,12768672 0,14389426 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12768672 0,1438269 ! positive regulation of cell development GO:0010720 80 36 0,000 0,12768672 0,14375959 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12768672 0,14369235 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12768672 0,14362518 ! aerobic respiration GO:0009060 55 36 0,000 0,12768672 0,14355806 ! embryonic organ development GO:0048568 57 36 0,000 0,12768672 0,14349101 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13099259 0,14713733 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13099259 0,14706867 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13099259 0,14700007 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13099259 0,14693154 ! organic anion transport GO:0015711 68 37 0,000 0,13099259 0,14686308 ! tissue remodeling GO:0048771 76 37 0,000 0,13099259 0,14679467 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,13099259 0,14672633 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13099259 0,14665806 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13099259 0,14658984 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13099259 0,14652169 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,13099259 0,14645361 ! spermatid differentiation GO:0048515 66 37 0,000 0,13099259 0,14638558 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13428603 0,14999637 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13428603 0,14992677 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13428603 0,14985723 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13428603 0,14978776 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,13428603 0,14971835 ! lipid homeostasis GO:0055088 67 38 0,000 0,13428603 0,149649 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13428603 0,14957972 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,13428603 0,1495105 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13428603 0,14944135 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13428603 0,14937226 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,13428603 0,14930323 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13428603 0,14923427 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1375671 0,15281 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1375671 0,15273948 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1375671 0,15266903 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1375671 0,15259864 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1375671 0,15252832 ! RNA modification GO:0009451 57 39 0,000 0,1375671 0,15245806 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1375671 0,15238787 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,14083585 0,15593698 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14083585 0,15586525 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14083585 0,15579359 ! feeding behavior GO:0007631 59 40 0,000 0,14083585 0,15572199 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,14083585 0,15565046 ! mesenchymal cell development GO:0014031 87 40 0,000 0,14083585 0,155579 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14083585 0,1555076 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14409232 0,15903033 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14409232 0,15895741 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14409232 0,15888456 ! gliogenesis GO:0042063 88 41 0,000 0,14409232 0,15881178 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14409232 0,15873906 ! T cell differentiation GO:0030217 81 41 0,000 0,14409232 0,15866641 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14409232 0,15859383 ! polyol metabolic process GO:0019751 66 41 0,000 0,14409232 0,15852131 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14409232 0,15844886 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,14733655 0,16194232 ! regulation of tube size GO:0035150 71 42 0,000 0,14733655 0,16186837 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14733655 0,16179449 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,14733655 0,16172068 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,14733655 0,16164694 ! neuron migration GO:0001764 79 42 0,000 0,14733655 0,16157326 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,14733655 0,16149965 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15056859 0,16496722 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15056859 0,16489214 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15056859 0,16481712 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,15056859 0,16474217 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,15056859 0,16466728 ! neural tube development GO:0021915 77 43 0,000 0,15056859 0,16459247 ! striated muscle contraction GO:0006941 77 43 0,000 0,15056859 0,16451772 ! phagocytosis GO:0006909 90 43 0,000 0,15056859 0,16444304 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15056859 0,16436843 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15378848 0,1678073 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15378848 0,16773123 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15378848 0,16765523 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,15699628 0,17107475 ! glycolysis GO:0006096 65 45 0,000 0,15699628 0,17099731 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,15699628 0,17091993 ! leukocyte migration GO:0050900 68 45 0,000 0,15699628 0,17084263 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,15699628 0,1707654 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15699628 0,17068823 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15699628 0,17061114 ! cell growth GO:0016049 84 45 0,000 0,15699628 0,17053411 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16019203 0,1739269 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,16019203 0,17384845 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,16019203 0,17377007 ! positive regulation of defense response GO:0031349 76 47 0,000 0,16337576 0,1771438 ! response to calcium ion GO:0051592 81 47 0,000 0,16337576 0,177064 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,16337576 0,17698428 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,16337576 0,17690463 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,16337576 0,17682505 ! JNK cascade GO:0007254 91 47 0,000 0,16337576 0,17674554 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,16337576 0,17666611 ! protein homooligomerization GO:0051260 76 47 0,000 0,16337576 0,17658674 ! mitochondrial transport GO:0006839 82 48 0,000 0,16654753 0,17993416 ! Notch signaling pathway GO:0007219 96 48 0,000 0,16654753 0,1798534 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,16654753 0,17977271 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,16654753 0,17969209 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,16654753 0,17961155 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,16654753 0,17953108 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,16654753 0,17945068 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,16970739 0,18277349 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,16970739 0,18269171 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,16970739 0,18261 ! regulation of ion transport GO:0043269 77 49 0,000 0,16970739 0,18252837 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,16970739 0,18244681 ! peptide metabolic process GO:0006518 76 49 0,000 0,16970739 0,18236533 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,16970739 0,18228391 ! endocrine system development GO:0035270 104 49 0,000 0,16970739 0,18220257 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,16970739 0,18212131 ! neuromuscular process GO:0050905 99 50 0,000 0,17285536 0,18541685 ! regulation of ossification GO:0030278 117 50 0,000 0,17285536 0,18533422 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,17285536 0,18525167 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17599151 0,18852875 ! excretion GO:0007588 83 51 0,000 0,17599151 0,18844484 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,17599151 0,18836102 ! chromatin remodeling GO:0006338 109 51 0,000 0,17599151 0,18827726 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,17599151 0,18819359 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,17599151 0,18810998 ! vesicle organization GO:0016050 107 51 0,000 0,17599151 0,18802645 ! regulation of cell shape GO:0008360 125 51 0,000 0,17599151 0,18794299 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,17599151 0,18785961 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,17911587 0,19110988 ! membrane fusion GO:0006944 110 52 0,000 0,17911587 0,19102517 ! cartilage development GO:0051216 90 52 0,000 0,17911587 0,19094053 ! RNA catabolic process GO:0006401 93 53 0,000 0,18222848 0,1941726 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,18222848 0,19408664 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,18222848 0,19400076 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,18222848 0,19391496 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,18222848 0,19382923 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,1853294 0,19704045 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1853294 0,19695342 ! cell recognition GO:0008037 85 54 0,000 0,1853294 0,19686646 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1853294 0,19677958 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,1853294 0,19669278 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1853294 0,19660605 ! chloride transport GO:0006821 90 55 0,000 0,18841866 0,19979519 ! glucose catabolic process GO:0006007 82 55 0,000 0,18841866 0,19970718 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,18841866 0,19961924 ! gastrulation GO:0007369 112 55 0,000 0,18841866 0,19953138 ! RNA elongation GO:0006354 79 55 0,000 0,18841866 0,1994436 ! nuclear export GO:0051168 97 55 0,000 0,18841866 0,19935589 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,18841866 0,19926826 ! regulation of actin filament length GO:0030832 105 56 0,000 0,19149631 0,20243415 ! sensory perception of smell GO:0007608 80 56 0,000 0,19149631 0,20234524 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,19149631 0,20225642 ! proton transport GO:0015992 94 56 0,000 0,19149631 0,20216767 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,19456239 0,20531452 ! hydrogen transport GO:0006818 97 58 0,000 0,19761694 0,20844645 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,19761694 0,20835511 ! regulation of endocytosis GO:0030100 91 58 0,000 0,19761694 0,20826385 ! adult behavior GO:0030534 99 58 0,000 0,19761694 0,20817266 ! positive regulation of secretion GO:0051047 95 59 0,000 0,20066001 0,21128577 ! regulation of cellular component size GO:0032535 109 59 0,000 0,20066001 0,21119335 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,20066001 0,211101 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,20066001 0,21100874 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,20369164 0,21410314 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,20369164 0,21400965 ! regulation of heart contraction GO:0008016 110 60 0,000 0,20369164 0,21391623 ! camera-type eye development GO:0043010 116 60 0,000 0,20369164 0,2138229 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,20369164 0,21372965 ! kidney development GO:0001822 122 60 0,000 0,20369164 0,21363648 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20671188 0,21670971 ! mesoderm development GO:0007498 119 61 0,000 0,20671188 0,21661532 ! tRNA processing GO:0008033 89 61 0,000 0,20671188 0,21652102 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20671188 0,21642679 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,20972075 0,21948157 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,21271832 0,22252186 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,21271832 0,22242515 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,21570462 0,22544974 ! cell redox homeostasis GO:0045454 102 64 0,000 0,21570462 0,22535185 ! single fertilization GO:0007338 75 64 0,000 0,21570462 0,22525404 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,21867968 0,22826174 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,21867968 0,22816276 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,22164356 0,23115492 ! extracellular matrix organization GO:0030198 133 66 0,000 0,22164356 0,23105477 ! secondary metabolic process GO:0019748 116 66 0,000 0,22164356 0,2309547 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,2245963 0,23393017 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,2245963 0,23382894 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,2245963 0,23372781 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,2245963 0,23362676 ! chromosome segregation GO:0007059 113 67 0,000 0,2245963 0,23352579 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,2245963 0,23342492 ! hexose catabolic process GO:0019320 104 67 0,000 0,2245963 0,23332413 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,2245963 0,23322343 ! activation of immune response GO:0002253 105 67 0,000 0,2245963 0,23312282 ! amino acid transport GO:0006865 125 68 0,000 0,22753793 0,23607428 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,22753793 0,23597252 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,22753793 0,23587085 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,22753793 0,23576927 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,22753793 0,23566778 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,22753793 0,23556637 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,2304685 0,23849772 ! urogenital system development GO:0001655 137 69 0,000 0,2304685 0,23839519 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2304685 0,23829274 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2304685 0,23819038 ! antigen processing and presentation GO:0019882 104 69 0,000 0,2304685 0,23808811 ! amine catabolic process GO:0009310 117 71 0,000 0,23629661 0,24400414 ! humoral immune response GO:0006959 109 71 0,000 0,23629661 0,24389947 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,23629661 0,24379488 ! regulation of immune effector process GO:0002697 137 71 0,000 0,23629661 0,24369038 ! acute inflammatory response GO:0002526 113 72 0,000 0,23919424 0,24657299 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,23919424 0,24646739 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,23919424 0,24636188 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,23919424 0,24625646 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,23919424 0,24615113 ! regulation of blood pressure GO:0008217 125 73 0,000 0,24208098 0,24901532 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,24208098 0,2489089 ! fertilization GO:0009566 90 73 0,000 0,24208098 0,24880257 ! transition metal ion transport GO:0000041 126 74 0,000 0,24495685 0,2516508 ! neurotransmitter transport GO:0006836 123 74 0,000 0,24495685 0,2515434 ! exocytosis GO:0006887 133 74 0,000 0,24495685 0,25143608 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,24495685 0,25132886 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,24782191 0,25416006 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,24782191 0,25405177 ! rhythmic process GO:0048511 128 75 0,000 0,24782191 0,25394357 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,25067619 0,25675901 ! defense response to bacterium GO:0042742 89 76 0,000 0,25067619 0,25664975 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,25067619 0,25654058 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,25067619 0,25643151 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,25351973 0,25923012 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,25351973 0,25912 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,25351973 0,25900997 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,25351973 0,25890003 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,25635258 0,26168193 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,25635258 0,26157095 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,25917477 0,26433849 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,25917477 0,26422648 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,25917477 0,26411457 ! response to metal ion GO:0010038 140 80 0,000 0,26198635 0,2668667 ! muscle cell differentiation GO:0042692 159 80 0,000 0,26198635 0,26675377 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,26198635 0,26664093 ! inorganic anion transport GO:0015698 138 80 0,000 0,26198635 0,26652818 ! T cell activation GO:0042110 168 81 0,000 0,26478734 0,26926388 ! digestion GO:0007586 112 81 0,000 0,26478734 0,26915013 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,26478734 0,26903646 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,26478734 0,2689229 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,2675778 0,27164228 ! negative regulation of growth GO:0045926 155 84 0,000 0,27312727 0,27715909 ! regulation of ligase activity GO:0051340 142 84 0,000 0,27312727 0,27704224 ! response to unfolded protein GO:0006986 131 85 0,000 0,27588635 0,27972295 ! nucleosome assembly GO:0006334 122 85 0,000 0,27588635 0,27960512 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,27588635 0,27948739 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,27863505 0,28215317 ! response to inorganic substance GO:0010035 153 86 0,000 0,27863505 0,28203447 ! chromatin assembly GO:0031497 124 86 0,000 0,27863505 0,28191586 ! alcohol catabolic process GO:0046164 130 86 0,000 0,27863505 0,28179736 ! amine transport GO:0015837 155 86 0,000 0,27863505 0,28167896 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,2813734 0,28432777 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,28410146 0,28696394 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,28410146 0,28684352 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,28681924 0,28946607 ! ossification GO:0001503 188 90 0,000 0,2895268 0,2920761 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,2895268 0,29195368 ! bone development GO:0060348 189 91 0,000 0,29222417 0,29455022 ! sterol metabolic process GO:0016125 152 91 0,000 0,29222417 0,29442687 ! response to protein stimulus GO:0051789 149 91 0,000 0,29222417 0,29430363 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,29222417 0,29418049 ! regulation of defense response GO:0031347 149 92 0,000 0,29491139 0,29676153 ! nucleosome organization GO:0034728 138 92 0,000 0,29491139 0,29663746 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,29491139 0,2965135 ! vitamin metabolic process GO:0006766 139 92 0,000 0,29491139 0,29638965 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2975885 0,29895529 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,30025553 0,30150868 ! forebrain development GO:0030900 188 95 0,000 0,30291252 0,30404987 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,30291252 0,30392307 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,30555951 0,3064511 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,30555951 0,30632341 ! positive regulation of immune response GO:0050778 156 96 0,000 0,30555951 0,30619583 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,30819654 0,30870977 ! hormone metabolic process GO:0042445 157 97 0,000 0,30819654 0,30858131 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,31082364 0,31108223 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,31082364 0,31095288 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,31344086 0,31344086