pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6223-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! ER overload response GO:0006983 6 6 2,000 1,484E-06 2,734E-03 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 2,053E-06 1,892E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 3,000 4,109E-06 2,524E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 5,594E-06 2,577E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 8,519E-06 3,14E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 1,206E-05 3,704E-03 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 1,206E-05 3,175E-03 ! DNA damage response, signal transduction GO:0042770 37 37 3,000 1,756E-05 4,045E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 2,078E-05 4,255E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 2,078E-05 3,83E-03 ! protein tetramerization GO:0051262 13 13 2,000 2,078E-05 3,482E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 2,637E-05 4,05E-03 ! cell cycle checkpoint GO:0000075 42 41 3,000 2,66E-05 3,771E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 3,287E-05 4,327E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 3,287E-05 4,038E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 2,000 4,033E-05 4,646E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 5,432E-05 5,889E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 5,842E-05 5,982E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 5,842E-05 5,667E-03 ! response to hormone stimulus GO:0009725 102 100 4,000 6,266E-05 5,774E-03 ! DNA damage checkpoint GO:0000077 19 19 2,000 6,917E-05 6,071E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 9,439E-05 7,907E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 9,439E-05 7,563E-03 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 1,09E-04 8,368E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 1,132E-04 8,345E-03 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 1,249E-04 8,857E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 1,424E-04 9,719E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,613E-04 0,01061806 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,755E-04 0,01115332 ! double-strand break repair GO:0006302 27 26 2,000 1,818E-04 0,0111699 ! response to insulin stimulus GO:0032868 28 26 2,000 1,818E-04 0,01080958 ! positive regulation of protein ubiquitination GO:0031398 5 5 1,000 1,823E-04 0,01050125 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,823E-04 0,01018303 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,823E-04 9,884E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,823E-04 9,601E-03 ! postreplication repair GO:0006301 5 5 1,000 1,823E-04 9,334E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,823E-04 9,082E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 1,000 1,823E-04 8,843E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,823E-04 8,616E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,823E-04 8,401E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 2,039E-04 9,168E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 2,086E-04 9,154E-03 ! regulation of cell migration GO:0030334 71 71 3,000 2,33E-04 9,988E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,533E-04 0,0106091 ! response to UV GO:0009411 29 29 2,000 2,533E-04 0,01037334 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,728E-04 0,0109281 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,728E-04 0,01069559 ! focal adhesion formation GO:0048041 7 6 1,000 2,728E-04 0,01047277 ! vascular smooth muscle contraction GO:0014829 6 6 1,000 2,728E-04 0,01025904 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,728E-04 0,01005386 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 2,728E-04 9,857E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,728E-04 9,667E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,728E-04 9,485E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,728E-04 9,309E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,728E-04 9,14E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,728E-04 8,977E-03 ! localization within membrane GO:0051668 6 6 1,000 2,728E-04 8,819E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 3,097E-04 9,843E-03 ! negative regulation of cell growth GO:0030308 32 32 2,000 3,408E-04 0,01064532 ! regulation of locomotion GO:0040012 79 79 3,000 3,517E-04 0,01080453 ! regulation of cell motion GO:0051270 79 79 3,000 3,517E-04 0,01062741 ! negative regulation of cell size GO:0045792 33 33 2,000 3,738E-04 0,01111052 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 3,808E-04 0,01114066 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 3,808E-04 0,01096659 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 7 7 1,000 3,808E-04 0,01079787 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,808E-04 0,01063427 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 3,808E-04 0,01047555 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,808E-04 0,0103215 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 3,808E-04 0,01017191 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 3,808E-04 0,0100266 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,808E-04 9,885E-03 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 4,087E-04 0,01046244 ! positive regulation of cell migration GO:0030335 36 36 2,000 4,848E-04 0,01224038 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 4,867E-04 0,01212192 ! sex determination GO:0007530 8 8 1,000 5,064E-04 0,01244372 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 5,064E-04 0,01227998 ! vasoconstriction GO:0042310 8 8 1,000 5,064E-04 0,0121205 ! regulation of fatty acid metabolic process GO:0019217 8 8 1,000 5,064E-04 0,01196511 ! peptidyl-serine modification GO:0018209 8 8 1,000 5,064E-04 0,01181366 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 5,064E-04 0,01166598 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 5,064E-04 0,01152196 ! heart development GO:0007507 90 87 3,000 5,086E-04 0,01143184 ! negative regulation of growth GO:0045926 37 37 2,000 5,261E-04 0,01168114 ! positive regulation of transferase activity GO:0051347 91 88 3,000 5,312E-04 0,01165573 GO:0033674|positive regulation of kinase activity, ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 5,695E-04 0,01234761 ! negative regulation of cell cycle GO:0045786 92 91 3,000 6,034E-04 0,01293046 ! protein oligomerization GO:0051259 39 39 2,000 6,151E-04 0,0130307 ! positive regulation of cell motion GO:0051272 39 39 2,000 6,151E-04 0,01288262 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 6,493E-04 0,01344582 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 6,493E-04 0,01329642 ! regulation of cellular pH GO:0030641 9 9 1,000 6,493E-04 0,01315031 ! histone acetylation GO:0016573 9 9 1,000 6,493E-04 0,01300737 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 6,63E-04 0,0131397 ! regulation of cell growth GO:0001558 97 96 3,000 7,387E-04 0,0144831 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 8,094E-04 0,0157031 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 8,094E-04 0,01553952 ! regulation of lipid biosynthetic process GO:0046890 10 10 1,000 8,094E-04 0,01537932 ! inositol metabolic process GO:0006020 10 10 1,000 8,094E-04 0,01522239 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 8,094E-04 0,01506863 ! centrosome cycle GO:0007098 10 10 1,000 8,094E-04 0,01491794 ! cell-substrate junction assembly GO:0007044 11 10 1,000 8,094E-04 0,01477024 ! neuromuscular junction development GO:0007528 10 10 1,000 8,094E-04 0,01462543 ! synaptic vesicle transport GO:0048489 11 10 1,000 8,094E-04 0,01448344 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 8,094E-04 0,01434418 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 9,866E-04 0,01731776 ! protein amino acid acetylation GO:0006473 11 11 1,000 9,866E-04 0,01715439 ! smooth muscle contraction GO:0006939 11 11 1,000 9,866E-04 0,01699406 ! cellular response to starvation GO:0009267 11 11 1,000 9,866E-04 0,01683671 ! regulation of cellular ketone metabolic process GO:0010565 11 11 1,000 9,866E-04 0,01668225 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 9,866E-04 0,01653059 ! G1/S transition checkpoint GO:0031575 12 11 1,000 9,866E-04 0,01638167 ! interaction with host GO:0051701 11 11 1,000 9,866E-04 0,0162354 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 9,866E-04 0,01609172 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 9,866E-04 0,01595057 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 9,866E-04 0,01581187 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 1,001E-03 0,01590255 ! microtubule organizing center organization GO:0031023 12 12 1,000 1,181E-03 0,01859939 GO:0051297|centrosome organization, ! somitogenesis GO:0001756 13 12 1,000 1,181E-03 0,01844176 ! G1 phase GO:0051318 13 12 1,000 1,181E-03 0,01828679 ! negative regulation of translation GO:0017148 12 12 1,000 1,181E-03 0,0181344 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,181E-03 0,01798453 ! ossification GO:0001503 50 49 2,000 1,204E-03 0,0181907 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 2,000 1,204E-03 0,01804281 GO:0060538|skeletal muscle organ development, ! anterior/posterior pattern formation GO:0009952 51 50 2,000 1,277E-03 0,01898384 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 1,353E-03 0,01995029 GO:0051325|interphase, ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,392E-03 0,02035575 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 1,392E-03 0,02019547 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,392E-03 0,02003769 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,392E-03 0,01988236 ! actin filament bundle formation GO:0051017 13 13 1,000 1,392E-03 0,01972942 ! cell aging GO:0007569 13 13 1,000 1,392E-03 0,01957881 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,392E-03 0,01943049 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,392E-03 0,01928439 ! response to light stimulus GO:0009416 53 52 2,000 1,432E-03 0,01969184 ! protein amino acid acylation GO:0043543 14 14 1,000 1,619E-03 0,02210515 ! base-excision repair GO:0006284 14 14 1,000 1,619E-03 0,02194261 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,863E-03 0,02506557 ! response to starvation GO:0042594 15 15 1,000 1,863E-03 0,02488394 ! response to ionizing radiation GO:0010212 16 15 1,000 1,863E-03 0,02470491 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,863E-03 0,02452845 ! spliceosomal snRNP biogenesis GO:0000387 16 16 1,000 2,124E-03 0,02775839 ! learning GO:0007612 16 16 1,000 2,124E-03 0,02756291 ! segmentation GO:0035282 17 16 1,000 2,124E-03 0,02737016 ! cellular response to nutrient levels GO:0031669 16 16 1,000 2,124E-03 0,02718009 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 2,124E-03 0,02699264 ! polyol metabolic process GO:0019751 16 16 1,000 2,124E-03 0,02680776 ! positive regulation of catabolic process GO:0009896 16 16 1,000 2,124E-03 0,0266254 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 2,4E-03 0,02989049 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 2,4E-03 0,02968988 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,4E-03 0,02949195 ! myelination GO:0042552 17 17 1,000 2,4E-03 0,02929663 ! glucose transport GO:0015758 17 17 1,000 2,4E-03 0,02910389 ! cell junction assembly GO:0034329 18 17 1,000 2,4E-03 0,02891367 ! negative regulation of cell development GO:0010721 18 17 1,000 2,4E-03 0,02872592 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 2,4E-03 0,02854059 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,693E-03 0,03181607 ! hexose transport GO:0008645 18 18 1,000 2,693E-03 0,03161342 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 18 18 1,000 2,693E-03 0,03141333 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,693E-03 0,03121576 ! ensheathment of neurons GO:0007272 18 18 1,000 2,693E-03 0,03102066 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 2,693E-03 0,03082799 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,693E-03 0,03063769 ! striated muscle tissue development GO:0014706 69 67 2,000 2,97E-03 0,03357954 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 3,002E-03 0,03373309 ! regulation of pH GO:0006885 19 19 1,000 3,002E-03 0,03352864 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 3,002E-03 0,03332666 ! peripheral nervous system development GO:0007422 19 19 1,000 3,002E-03 0,0331271 ! response to radiation GO:0009314 70 68 2,000 3,098E-03 0,03398405 ! regulation of cell size GO:0008361 68 68 2,000 3,098E-03 0,03378296 ! regionalization GO:0003002 70 69 2,000 3,229E-03 0,035008 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 3,326E-03 0,03584972 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 3,326E-03 0,03564129 ! positive regulation of transport GO:0051050 71 70 2,000 3,364E-03 0,03583604 ! muscle tissue development GO:0060537 72 70 2,000 3,364E-03 0,03563009 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 3,644E-03 0,03837203 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 3,666E-03 0,03839367 ! mammary gland development GO:0030879 23 21 1,000 3,666E-03 0,03817675 ! regulation of action potential in neuron GO:0019228 21 21 1,000 3,666E-03 0,03796228 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,666E-03 0,0377502 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 4,022E-03 0,04118295 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 1,000 4,022E-03 0,04095542 ! cell junction organization GO:0034330 23 22 1,000 4,022E-03 0,04073039 ! response to estrogen stimulus GO:0043627 23 23 1,000 4,393E-03 0,04424586 ! positive regulation of growth GO:0045927 23 23 1,000 4,393E-03 0,0440054 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 4,393E-03 0,04376753 ! calcium-mediated signaling GO:0019722 23 23 1,000 4,393E-03 0,04353222 ! cell projection assembly GO:0030031 25 23 1,000 4,393E-03 0,04329943 ! regulation of protein modification process GO:0031399 79 78 2,000 4,567E-03 0,04476817 ! nuclear transport GO:0051169 79 79 2,000 4,733E-03 0,04615372 GO:0006913|nucleocytoplasmic transport, ! mitochondrial transport GO:0006839 24 24 1,000 4,78E-03 0,04636436 ! regulation of action potential GO:0001508 24 24 1,000 4,78E-03 0,04612162 ! glucose homeostasis GO:0042593 24 24 1,000 4,78E-03 0,0458814 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 4,78E-03 0,04564367 ! glucan metabolic process GO:0044042 25 24 1,000 4,78E-03 0,04540839 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of intracellular protein transport GO:0033157 25 25 1,000 5,181E-03 0,04897126 ! positive regulation of DNA binding GO:0043388 26 25 1,000 5,181E-03 0,04872141 ! regulation of T cell proliferation GO:0042129 25 25 1,000 5,181E-03 0,04847409 ! heart morphogenesis GO:0003007 25 25 1,000 5,181E-03 0,04822927 ! negative regulation of immune system process GO:0002683 25 25 1,000 5,181E-03 0,04798691 ! positive regulation of binding GO:0051099 27 26 1,000 5,598E-03 0,05158627 ! negative regulation of cell migration GO:0030336 26 26 1,000 5,598E-03 0,05132962 ! regulation of T cell differentiation GO:0045580 26 26 1,000 5,598E-03 0,05107552 ! regulation of blood vessel size GO:0050880 27 26 1,000 5,598E-03 0,05082391 GO:0035150|regulation of tube size, ! synapse organization GO:0050808 26 26 1,000 5,598E-03 0,05057477 ! regulation of cellular localization GO:0060341 86 85 2,000 5,809E-03 0,05222136 ! energy reserve metabolic process GO:0006112 28 27 1,000 6,03E-03 0,05394449 ! learning or memory GO:0007611 28 27 1,000 6,03E-03 0,05368389 ! activation of caspase activity GO:0006919 27 27 1,000 6,03E-03 0,05342579 ! carbohydrate transport GO:0008643 28 28 1,000 6,476E-03 0,05710569 ! histone modification GO:0016570 28 28 1,000 6,476E-03 0,05683376 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 6,476E-03 0,0565644 ! positive regulation of cell cycle GO:0045787 29 29 1,000 6,937E-03 0,06030468 ! viral reproductive process GO:0022415 29 29 1,000 6,937E-03 0,06002156 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 6,937E-03 0,05974108 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 6,937E-03 0,05946322 ! covalent chromatin modification GO:0016569 29 29 1,000 6,937E-03 0,05918792 ! positive regulation of protein transport GO:0051222 29 29 1,000 6,937E-03 0,05891517 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 7,412E-03 0,06266439 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 7,412E-03 0,06237826 GO:0010863|positive regulation of phospholipase C activity, ! vascular process in circulatory system GO:0003018 31 30 1,000 7,412E-03 0,06209472 ! pattern specification process GO:0007389 96 94 2,000 7,678E-03 0,06403171 ! skeletal muscle fiber development GO:0048741 31 31 1,000 7,902E-03 0,06560178 ! B cell activation GO:0042113 31 31 1,000 7,902E-03 0,0653076 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 7,902E-03 0,06501605 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 7,902E-03 0,06472709 ! aging GO:0007568 32 31 1,000 7,902E-03 0,06444068 ! negative regulation of cell motion GO:0051271 31 31 1,000 7,902E-03 0,0641568 ! muscle fiber development GO:0048747 32 32 1,000 8,406E-03 0,06795013 ! regulation of phospholipase activity GO:0010517 32 32 1,000 8,406E-03 0,0676534 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 8,406E-03 0,06735926 ! nuclear export GO:0051168 32 32 1,000 8,406E-03 0,06706766 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 8,406E-03 0,06677857 ! positive regulation of lipase activity GO:0060193 32 32 1,000 8,406E-03 0,06649197 ! regulation of cellular response to stress GO:0080135 35 33 1,000 8,924E-03 0,07028937 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 8,924E-03 0,06999026 ! muscle organ development GO:0007517 102 100 2,000 9,101E-03 0,07107537 ! regulation of angiogenesis GO:0045765 35 34 1,000 9,457E-03 0,07353845 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 9,457E-03 0,07322947 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 9,457E-03 0,07292307 ! viral reproduction GO:0016032 34 34 1,000 9,457E-03 0,07261922 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,01000277 0,07649421 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01000277 0,07617812 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,01000277 0,07586463 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01056265 0,07978263 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lipase activity GO:0060191 36 36 1,000 0,01056265 0,07945698 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01113617 0,08343072 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,01113617 0,08309294 ! lung development GO:0030324 38 37 1,000 0,01113617 0,08275789 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,01172321 0,08677056 ! chromosome segregation GO:0007059 38 38 1,000 0,01172321 0,08642347 ! axon guidance GO:0007411 39 38 1,000 0,01172321 0,08607916 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,01232364 0,09012886 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01232364 0,08977262 ! respiratory tube development GO:0030323 40 39 1,000 0,01232364 0,08941919 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01232364 0,08906852 ! respiratory system development GO:0060541 40 39 1,000 0,01232364 0,0887206 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01232364 0,08837538 ! regulation of caspase activity GO:0043281 41 41 1,000 0,01356423 0,09689489 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,01420415 0,10107432 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,01420415 0,10068557 ! mitochondrion organization GO:0007005 44 43 1,000 0,01485699 0,1049097 ! mRNA transport GO:0051028 44 44 1,000 0,01552264 0,10919168 ! protein import into nucleus GO:0006606 44 44 1,000 0,01552264 0,1087765 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,01552264 0,10836447 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01620097 0,11267318 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01620097 0,1122496 ! nuclear import GO:0051170 45 45 1,000 0,01620097 0,11182919 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,01620097 0,11141192 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01689188 0,11573139 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01689188 0,11530275 ! regulation of blood pressure GO:0008217 48 47 1,000 0,01759526 0,11966073 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01759526 0,1192208 ! actin filament organization GO:0007015 50 48 1,000 0,01831097 0,12361584 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,01831097 0,12316469 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01831097 0,12271681 ! DNA recombination GO:0006310 48 48 1,000 0,01831097 0,12227219 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01903892 0,12667413 ! gland development GO:0048732 51 49 1,000 0,01903892 0,12621847 ! cell cycle arrest GO:0007050 49 49 1,000 0,01903892 0,12576607 ! RNA transport GO:0050658 50 50 1,000 0,01977899 0,13018815 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 1,000 0,01977899 0,12972485 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01977899 0,12926483 ! RNA localization GO:0006403 52 52 1,000 0,02129504 0,13868114 ! cell fate commitment GO:0045165 52 52 1,000 0,02129504 0,13819282 ! rRNA transcription GO:0009303 5 5 0,000 0,02161925 0,13980446 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02161925 0,13931564 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02161925 0,13883022 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02161925 0,13834817 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02161925 0,13786945 ! reproductive cellular process GO:0048610 5 5 0,000 0,02161925 0,13739404 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02161925 0,1369219 ! prostate gland development GO:0030850 5 5 0,000 0,02161925 0,13645299 ! metencephalon development GO:0022037 5 5 0,000 0,02161925 0,13598728 ! water transport GO:0006833 5 5 0,000 0,02161925 0,13552474 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02161925 0,13506533 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02161925 0,13460903 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02161925 0,1341558 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02161925 0,13370561 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02161925 0,13325844 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02161925 0,13281424 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02161925 0,132373 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02161925 0,13193468 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02161925 0,13149925 ! filopodium assembly GO:0046847 7 5 0,000 0,02161925 0,13106669 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02161925 0,13063696 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02161925 0,13021004 ! GTP metabolic process GO:0046039 5 5 0,000 0,02161925 0,1297859 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02161925 0,12936452 ! mRNA stabilization GO:0048255 5 5 0,000 0,02161925 0,12894587 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02161925 0,12852991 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02161925 0,12811663 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02161925 0,127706 ! social behavior GO:0035176 5 5 0,000 0,02161925 0,12729799 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02161925 0,12689259 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02161925 0,12648975 ! memory GO:0007613 5 5 0,000 0,02161925 0,12608947 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02161925 0,12569171 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02161925 0,12529645 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02161925 0,12490368 ! response to lipid GO:0033993 5 5 0,000 0,02161925 0,12451335 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02161925 0,12412546 ! hippocampus development GO:0021766 6 5 0,000 0,02161925 0,12373998 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02161925 0,12335688 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02161925 0,12297615 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02161925 0,12259776 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02161925 0,12222169 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02161925 0,12184793 ! heart looping GO:0001947 5 5 0,000 0,02161925 0,12147644 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02161925 0,12110721 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02161925 0,12074022 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02161925 0,12037545 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02161925 0,12001287 ! pH reduction GO:0045851 5 5 0,000 0,02161925 0,11965247 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02161925 0,11929423 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02161925 0,11893813 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02161925 0,11858414 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02161925 0,11823226 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02161925 0,11788246 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02161925 0,11753473 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02161925 0,11718904 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02161925 0,11684537 ! adrenal gland development GO:0030325 5 5 0,000 0,02161925 0,11650372 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02161925 0,11616406 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02161925 0,11582637 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02161925 0,11549064 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02161925 0,11515686 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02161925 0,11482499 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02161925 0,11449504 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02161925 0,11416697 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02161925 0,11384078 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02161925 0,11351645 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02161925 0,11319396 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02161925 0,11287329 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02161925 0,11255444 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02161925 0,11223739 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02161925 0,11192211 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02161925 0,11160861 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02161925 0,11129685 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02161925 0,11098683 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02161925 0,11067853 ! response to ATP GO:0033198 5 5 0,000 0,02161925 0,11037195 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02161925 0,11006705 ! regulation of appetite GO:0032098 5 5 0,000 0,02161925 0,10976384 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02161925 0,10946229 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02161925 0,10916239 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02161925 0,10886413 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02161925 0,1085675 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02161925 0,10827248 ! receptor clustering GO:0043113 5 5 0,000 0,02161925 0,10797906 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02161925 0,10768722 ! fear response GO:0042596 5 5 0,000 0,02161925 0,10739696 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02161925 0,10710826 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02161925 0,10682111 ! retinol metabolic process GO:0042572 5 5 0,000 0,02161925 0,10653549 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02161925 0,10625139 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02161925 0,10596881 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02161925 0,10568773 ! parturition GO:0007567 5 5 0,000 0,02161925 0,10540813 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02161925 0,10513001 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02161925 0,10485335 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02161925 0,10457814 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02161925 0,10430438 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02161925 0,10403204 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02161925 0,10376113 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02161925 0,10349162 ! response to UV-B GO:0010224 5 5 0,000 0,02161925 0,1032235 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02161925 0,10295678 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02161925 0,10269142 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02161925 0,10242744 ! interaction with symbiont GO:0051702 5 5 0,000 0,02161925 0,1021648 ! cellular extravasation GO:0045123 5 5 0,000 0,02161925 0,10190351 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02161925 0,10164355 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02161925 0,10138492 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02161925 0,10112759 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02161925 0,10087158 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02161925 0,10061685 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02161925 0,10036341 ! response to amine stimulus GO:0014075 5 5 0,000 0,02161925 0,10011124 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02161925 0,09986033 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02161925 0,09961068 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02161925 0,09936228 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02161925 0,09911511 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02161925 0,09886916 ! neuron recognition GO:0008038 5 5 0,000 0,02161925 0,09862444 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02161925 0,09838092 ! decidualization GO:0046697 5 5 0,000 0,02161925 0,0981386 ! hair follicle maturation GO:0048820 5 5 0,000 0,02161925 0,09789748 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02161925 0,09765753 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02161925 0,09741876 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02161925 0,09718115 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02161925 0,0969447 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02161925 0,0967094 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02161925 0,09647524 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02161925 0,0962422 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02161925 0,09601029 ! histone methylation GO:0016571 5 5 0,000 0,02161925 0,0957795 ! DNA methylation GO:0006306 5 5 0,000 0,02161925 0,09554981 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02161925 0,09532123 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02161925 0,09509373 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02161925 0,09486732 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02161925 0,09464198 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02161925 0,09441771 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02161925 0,0941945 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02161925 0,09397234 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02161925 0,09375123 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02161925 0,09353116 ! sterol catabolic process GO:0016127 5 5 0,000 0,02161925 0,09331211 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02161925 0,09309409 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02161925 0,09287709 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02161925 0,0926611 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02161925 0,09244611 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02161925 0,09223211 ! zymogen activation GO:0031638 5 5 0,000 0,02161925 0,0920191 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02161925 0,09180708 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02161925 0,09159603 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02161925 0,09138595 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02161925 0,09117682 ! nucleosome positioning GO:0016584 5 5 0,000 0,02161925 0,09096866 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02161925 0,09076144 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02161925 0,09055516 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02161925 0,09034982 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02161925 0,09014541 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02161925 0,08994192 ! NADPH regeneration GO:0006740 5 5 0,000 0,02161925 0,08973935 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02161925 0,08953769 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02161925 0,08933693 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02161925 0,08913707 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02161925 0,08893811 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02161925 0,08874003 ! sarcomere organization GO:0045214 5 5 0,000 0,02161925 0,08854283 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02161925 0,0883465 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02161925 0,08815104 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02161925 0,08795645 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02161925 0,08776271 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02161925 0,08756983 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02161925 0,08737779 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02161925 0,08718659 ! spleen development GO:0048536 5 5 0,000 0,02161925 0,08699623 ! male genitalia development GO:0030539 5 5 0,000 0,02161925 0,08680669 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02161925 0,08661798 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02161925 0,08643009 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02161925 0,08624301 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02161925 0,08605674 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02161925 0,08587128 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02161925 0,08568661 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02161925 0,08550273 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02161925 0,08531964 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02161925 0,08513733 ! ATP catabolic process GO:0006200 5 5 0,000 0,02161925 0,0849558 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02161925 0,08477505 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02161925 0,08459506 ! blastocyst formation GO:0001825 5 5 0,000 0,02161925 0,08441583 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02161925 0,08423736 ! embryonic gut development GO:0048566 5 5 0,000 0,02161925 0,08405965 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02161925 0,08388268 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02161925 0,08370645 ! activation of innate immune response GO:0002218 5 5 0,000 0,02161925 0,08353097 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02161925 0,08335622 ! catecholamine transport GO:0051937 5 5 0,000 0,02161925 0,0831822 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02161925 0,0830089 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02161925 0,08283633 ! muscle adaptation GO:0043500 5 5 0,000 0,02161925 0,08266447 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02161925 0,08249332 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02161925 0,08232288 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02161925 0,08215314 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02161925 0,0819841 ! defense response to fungus GO:0050832 5 5 0,000 0,02161925 0,08181575 ! lysogeny GO:0030069 5 5 0,000 0,02161925 0,0816481 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02161925 0,08148113 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02161925 0,08131484 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02161925 0,08114923 ! response to nicotine GO:0035094 5 5 0,000 0,02161925 0,08098429 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02161925 0,08082003 ! mitochondrion localization GO:0051646 5 5 0,000 0,02161925 0,08065642 ! nucleus localization GO:0051647 5 5 0,000 0,02161925 0,08049348 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02161925 0,08033119 ! response to hypoxia GO:0001666 53 53 1,000 0,0220708 0,08184403 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,0220708 0,08167969 ! regulation of T cell activation GO:0050863 53 53 1,000 0,0220708 0,081516 ! regulation of protein transport GO:0051223 53 53 1,000 0,0220708 0,08135297 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,02285823 0,08408728 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,02365723 0,08685315 ! in utero embryonic development GO:0001701 55 55 1,000 0,02365723 0,08668048 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,02365723 0,0865085 ! reproductive developmental process GO:0003006 56 56 1,000 0,02446769 0,08929497 ! extracellular structure organization GO:0043062 56 56 1,000 0,02446769 0,08911849 ! regulation of nervous system development GO:0051960 57 56 1,000 0,02446769 0,08894272 ! regulation of binding GO:0051098 60 57 1,000 0,0252895 0,09174911 ! regulation of protein localization GO:0032880 58 57 1,000 0,0252895 0,09156886 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02588854 0,09355409 ! axon extension GO:0048675 7 6 0,000 0,02588854 0,09337101 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02588854 0,09318865 ! tRNA modification GO:0006400 6 6 0,000 0,02588854 0,09300699 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02588854 0,09282605 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02588854 0,0926458 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02588854 0,09246626 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02588854 0,0922874 ! regulation of S phase GO:0033261 6 6 0,000 0,02588854 0,09210924 ! myotube differentiation GO:0014902 6 6 0,000 0,02588854 0,09193177 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02588854 0,09175498 ! bone remodeling GO:0046849 6 6 0,000 0,02588854 0,09157886 ! N-glycan processing GO:0006491 6 6 0,000 0,02588854 0,09140343 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02588854 0,09122866 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02588854 0,09105456 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02588854 0,09088112 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02588854 0,09070834 ! RNA methylation GO:0001510 6 6 0,000 0,02588854 0,09053622 ! cartilage condensation GO:0001502 7 6 0,000 0,02588854 0,09036475 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02588854 0,09019393 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02588854 0,09002375 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02588854 0,08985422 ! artery development GO:0060840 6 6 0,000 0,02588854 0,08968532 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02588854 0,08951705 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02588854 0,08934942 ! androgen metabolic process GO:0008209 6 6 0,000 0,02588854 0,08918241 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02588854 0,08901602 ! limbic system development GO:0021761 7 6 0,000 0,02588854 0,08885026 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02588854 0,08868511 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02588854 0,08852057 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02588854 0,08835664 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02588854 0,08819332 ! pathogenesis GO:0009405 6 6 0,000 0,02588854 0,08803061 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02588854 0,08786849 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02588854 0,08770696 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02588854 0,08754603 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02588854 0,08738569 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02588854 0,08722594 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02588854 0,08706677 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02588854 0,08690818 ! arginine metabolic process GO:0006525 6 6 0,000 0,02588854 0,08675016 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02588854 0,08659272 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02588854 0,08643585 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02588854 0,08627954 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02588854 0,08612381 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02588854 0,08596863 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02588854 0,08581401 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02588854 0,08565994 ! V(D)J recombination GO:0033151 6 6 0,000 0,02588854 0,08550643 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02588854 0,08535347 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02588854 0,08520105 ! regulation of heart rate GO:0002027 6 6 0,000 0,02588854 0,08504918 ! lipid digestion GO:0044241 6 6 0,000 0,02588854 0,08489784 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02588854 0,08474705 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02588854 0,08459679 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02588854 0,08444706 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02588854 0,08429786 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02588854 0,08414919 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02588854 0,08400104 ! ruffle organization GO:0031529 6 6 0,000 0,02588854 0,08385341 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02588854 0,0837063 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02588854 0,0835597 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02588854 0,08341362 ! L-amino acid transport GO:0015807 6 6 0,000 0,02588854 0,08326804 ! bone mineralization GO:0030282 6 6 0,000 0,02588854 0,08312298 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02588854 0,08297841 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02588854 0,08283435 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02588854 0,08269079 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02588854 0,08254773 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02588854 0,08240516 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02588854 0,08226308 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02588854 0,08212149 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02588854 0,08198039 ! regulation of organ growth GO:0046620 6 6 0,000 0,02588854 0,08183977 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02588854 0,08169964 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02588854 0,08155998 ! response to dsRNA GO:0043331 6 6 0,000 0,02588854 0,0814208 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02588854 0,08128209 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02588854 0,08114386 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02588854 0,08100609 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02588854 0,08086879 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02588854 0,08073196 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02588854 0,08059559 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02588854 0,08045968 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02588854 0,08032422 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02588854 0,08018922 ! erythrocyte development GO:0048821 6 6 0,000 0,02588854 0,08005468 ! renal water homeostasis GO:0003091 6 6 0,000 0,02588854 0,07992058 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02588854 0,07978694 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02588854 0,07965374 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02588854 0,07952098 ! ribosome assembly GO:0042255 6 6 0,000 0,02588854 0,07938867 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02588854 0,07925679 ! diencephalon development GO:0021536 6 6 0,000 0,02588854 0,07912535 ! fucose catabolic process GO:0019317 6 6 0,000 0,02588854 0,07899435 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02588854 0,07886378 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02588854 0,07873364 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02588854 0,07860393 ! regulation of cell division GO:0051302 6 6 0,000 0,02588854 0,07847465 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02588854 0,07834579 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02588854 0,07821736 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02588854 0,07808934 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02588854 0,07796175 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02588854 0,07783456 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02588854 0,0777078 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02588854 0,07758144 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02588854 0,0774555 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02588854 0,07732996 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02588854 0,07720484 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02588854 0,07708011 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02588854 0,07695579 ! thymus development GO:0048538 6 6 0,000 0,02588854 0,07683187 ! lymph node development GO:0048535 6 6 0,000 0,02588854 0,07670834 ! organic cation transport GO:0015695 6 6 0,000 0,02588854 0,07658521 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02588854 0,07646248 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02588854 0,07634014 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02588854 0,07621819 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02588854 0,07609663 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02588854 0,07597546 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02588854 0,07585467 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02588854 0,07573427 ! alditol metabolic process GO:0019400 6 6 0,000 0,02588854 0,07561424 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02588854 0,0754946 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02588854 0,07537534 ! maternal placenta development GO:0001893 6 6 0,000 0,02588854 0,07525645 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02588854 0,07513793 ! regulation of cell development GO:0060284 60 59 1,000 0,02696674 0,07814417 ! protein localization in organelle GO:0033365 59 59 1,000 0,02696674 0,0780215 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,02782195 0,08036968 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02868809 0,08274203 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,02868809 0,08261274 ! axonogenesis GO:0007409 66 62 1,000 0,02956505 0,08500529 ! protein import GO:0017038 62 62 1,000 0,02956505 0,08487288 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02956505 0,08474089 ! respiratory burst GO:0045730 7 7 0,000 0,03013983 0,08625421 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03013983 0,08612048 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03013983 0,08598717 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03013983 0,08585426 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03013983 0,08572177 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03013983 0,08558969 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03013983 0,08545801 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03013983 0,08532674 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03013983 0,08519587 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03013983 0,0850654 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03013983 0,08493534 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03013983 0,08480566 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03013983 0,08467639 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03013983 0,0845475 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03013983 0,08441901 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03013983 0,08429091 ! axis specification GO:0009798 7 7 0,000 0,03013983 0,0841632 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03013983 0,08403587 ! visual behavior GO:0007632 7 7 0,000 0,03013983 0,08390893 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03013983 0,08378237 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03013983 0,08365619 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03013983 0,08353039 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03013983 0,08340497 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03013983 0,08327992 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03013983 0,08315525 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03013983 0,08303096 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03013983 0,08290703 ! digestive system development GO:0055123 7 7 0,000 0,03013983 0,08278347 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03013983 0,08266028 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03013983 0,08253746 ! protein targeting to ER GO:0045047 8 7 0,000 0,03013983 0,082415 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03013983 0,0822929 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03013983 0,08217117 ! endoderm development GO:0007492 7 7 0,000 0,03013983 0,08204979 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03013983 0,08192877 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03013983 0,08180811 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03013983 0,08168781 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03013983 0,08156786 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03013983 0,08144825 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03013983 0,081329 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03013983 0,0812101 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03013983 0,08109155 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03013983 0,08097334 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03013983 0,08085547 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03013983 0,08073795 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03013983 0,08062077 ! UV protection GO:0009650 7 7 0,000 0,03013983 0,08050393 ! DNA integration GO:0015074 7 7 0,000 0,03013983 0,08038742 ! myofibril assembly GO:0030239 7 7 0,000 0,03013983 0,08027126 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03013983 0,08015542 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03013983 0,08003993 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03013983 0,07992476 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03013983 0,07980993 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03013983 0,07969542 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03013983 0,07958125 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03013983 0,0794674 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03013983 0,07935387 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03013983 0,07924067 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03013983 0,07912779 ! axon cargo transport GO:0008088 7 7 0,000 0,03013983 0,07901523 ! eating behavior GO:0042755 7 7 0,000 0,03013983 0,078903 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03013983 0,07879108 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03013983 0,07867947 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03013983 0,07856819 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03013983 0,07845722 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03013983 0,07834656 ! cranial nerve development GO:0021545 7 7 0,000 0,03013983 0,07823621 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03013983 0,07812617 ! induction of an organ GO:0001759 7 7 0,000 0,03013983 0,07801645 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03013983 0,07790703 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03013983 0,07779791 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03013983 0,0776891 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03013983 0,0775806 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03013983 0,0774724 ! platelet activation GO:0030168 8 7 0,000 0,03013983 0,0773645 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03013983 0,0772569 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03013983 0,0771496 ! natural killer cell activation GO:0030101 7 7 0,000 0,03013983 0,07704259 ! NADP metabolic process GO:0006739 7 7 0,000 0,03013983 0,07693589 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03013983 0,07682947 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03013983 0,07672336 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03013983 0,07661753 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03013983 0,076512 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03013983 0,07640675 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03013983 0,0763018 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03013983 0,07619713 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03013983 0,07609275 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03013983 0,07598866 ! cell-cell recognition GO:0009988 8 7 0,000 0,03013983 0,07588485 ! hormone catabolic process GO:0042447 7 7 0,000 0,03013983 0,07578132 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03013983 0,07567808 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03013983 0,07557511 ! oxygen transport GO:0015671 7 7 0,000 0,03013983 0,07547243 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03013983 0,07537003 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03013983 0,0752679 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03013983 0,07516605 ! regulation of axon extension GO:0030516 7 7 0,000 0,03013983 0,07506447 ! cell killing GO:0001906 7 7 0,000 0,03013983 0,07496317 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03013983 0,07486214 ! adult feeding behavior GO:0008343 7 7 0,000 0,03013983 0,07476139 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03013983 0,0746609 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03013983 0,07456068 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03013983 0,07446074 ! response to cold GO:0009409 7 7 0,000 0,03013983 0,07436106 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,03045273 0,07503259 ! angiogenesis GO:0001525 65 64 1,000 0,03135102 0,07714276 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,03135102 0,0770399 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,03135102 0,07693732 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,03317902 0,08131508 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,03317902 0,08120709 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,03410853 0,08337139 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! muscle contraction GO:0006936 67 67 1,000 0,03410853 0,08326096 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,03410853 0,08315083 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03437318 0,0836853 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03437318 0,0835749 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03437318 0,08346478 ! positive regulation of translation GO:0045727 8 8 0,000 0,03437318 0,08335496 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03437318 0,08324543 ! superoxide anion generation GO:0042554 8 8 0,000 0,03437318 0,08313618 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03437318 0,08302722 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03437318 0,08291855 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03437318 0,08281016 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03437318 0,08270205 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03437318 0,08259423 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03437318 0,08248668 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03437318 0,08237942 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03437318 0,08227243 ! zinc ion transport GO:0006829 8 8 0,000 0,03437318 0,08216572 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03437318 0,08205929 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03437318 0,08195313 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03437318 0,08184725 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03437318 0,08174164 ! lipid localization GO:0010876 8 8 0,000 0,03437318 0,0816363 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03437318 0,08153124 ! response to cAMP GO:0051591 8 8 0,000 0,03437318 0,08142644 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03437318 0,08132191 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03437318 0,08121765 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03437318 0,08111366 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03437318 0,08100994 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03437318 0,08090648 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03437318 0,08080328 ! sensory perception of taste GO:0050909 8 8 0,000 0,03437318 0,08070035 ! organelle fusion GO:0048284 8 8 0,000 0,03437318 0,08059767 ! pancreas development GO:0031016 8 8 0,000 0,03437318 0,08049526 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03437318 0,08039311 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03437318 0,08029122 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03437318 0,08018958 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03437318 0,08008821 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03437318 0,07998708 ! sperm motility GO:0030317 8 8 0,000 0,03437318 0,07988622 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03437318 0,07978561 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03437318 0,07968525 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03437318 0,07958514 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03437318 0,07948528 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03437318 0,07938568 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03437318 0,07928632 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03437318 0,07918721 ! Golgi organization GO:0007030 8 8 0,000 0,03437318 0,07908835 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03437318 0,07898974 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03437318 0,07889137 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03437318 0,07879325 ! fructose metabolic process GO:0006000 8 8 0,000 0,03437318 0,07869537 ! mannose metabolic process GO:0006013 9 8 0,000 0,03437318 0,07859773 ! NAD metabolic process GO:0019674 8 8 0,000 0,03437318 0,07850034 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03437318 0,07840318 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03437318 0,07830627 ! response to fungus GO:0009620 8 8 0,000 0,03437318 0,07820959 ! stem cell differentiation GO:0048863 8 8 0,000 0,03437318 0,07811316 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03437318 0,07801696 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03437318 0,077921 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03437318 0,07782527 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03437318 0,07772978 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03437318 0,07763452 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03437318 0,0775395 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03437318 0,07744471 ! muscle cell development GO:0055001 8 8 0,000 0,03437318 0,07735015 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03437318 0,07725582 ! sensory perception of pain GO:0019233 8 8 0,000 0,03437318 0,07716172 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03437318 0,07706785 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03437318 0,07697421 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03437318 0,07688079 ! chromatin silencing GO:0006342 8 8 0,000 0,03437318 0,0767876 ! tissue regeneration GO:0042246 8 8 0,000 0,03437318 0,07669464 ! salivary gland development GO:0007431 8 8 0,000 0,03437318 0,0766019 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03437318 0,07650939 ! T cell homeostasis GO:0043029 8 8 0,000 0,03437318 0,07641709 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03437318 0,07632503 ! water homeostasis GO:0030104 8 8 0,000 0,03437318 0,07623318 ! cofactor transport GO:0051181 8 8 0,000 0,03437318 0,07614155 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03437318 0,07605015 ! acid secretion GO:0046717 8 8 0,000 0,03437318 0,07595896 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03437318 0,07586799 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03437318 0,07577724 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03437318 0,0756867 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03437318 0,07559639 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03437318 0,07550628 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03437318 0,07541639 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03437318 0,07532672 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03437318 0,07523726 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03437318 0,07514801 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03437318 0,07505897 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03437318 0,07497014 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03437318 0,07488153 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03437318 0,07479312 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03437318 0,07470492 ! developmental induction GO:0031128 8 8 0,000 0,03437318 0,07461693 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03437318 0,07452914 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03437318 0,07444156 ! actin filament polymerization GO:0030041 9 8 0,000 0,03437318 0,07435419 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03437318 0,07426702 ! peptide hormone processing GO:0016486 8 8 0,000 0,03437318 0,07418006 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03437318 0,0740933 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03437318 0,07400674 ! regulation of translation GO:0006417 69 69 1,000 0,03599808 0,07741476 ! response to nutrient levels GO:0031667 69 69 1,000 0,03599808 0,07732454 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,03599808 0,07723452 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0369579 0,07920165 ! wound healing GO:0042060 74 70 1,000 0,0369579 0,07910966 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,03792764 0,08109123 ! regulation of cell activation GO:0050865 71 71 1,000 0,03792764 0,08099727 ! lactation GO:0007595 10 9 0,000 0,03858866 0,08231355 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03858866 0,08221839 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03858866 0,08212345 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03858866 0,08202873 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03858866 0,08193423 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03858866 0,08183994 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03858866 0,08174587 ! viral genome replication GO:0019079 9 9 0,000 0,03858866 0,08165202 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03858866 0,08155838 ! copper ion transport GO:0006825 9 9 0,000 0,03858866 0,08146496 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03858866 0,08137175 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03858866 0,08127875 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03858866 0,08118597 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03858866 0,0810934 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03858866 0,08100103 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03858866 0,08090888 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03858866 0,08081694 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03858866 0,08072521 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03858866 0,08063368 ! phospholipid efflux GO:0033700 9 9 0,000 0,03858866 0,08054236 ! response to alkaloid GO:0043279 10 9 0,000 0,03858866 0,08045125 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03858866 0,08036035 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03858866 0,08026965 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03858866 0,08017915 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03858866 0,08008886 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03858866 0,07999877 ! response to ethanol GO:0045471 9 9 0,000 0,03858866 0,07990888 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03858866 0,0798192 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03858866 0,07972972 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03858866 0,07964043 ! methionine metabolic process GO:0006555 9 9 0,000 0,03858866 0,07955135 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03858866 0,07946247 ! cerebral cortex development GO:0021987 9 9 0,000 0,03858866 0,07937378 ! response to osmotic stress GO:0006970 9 9 0,000 0,03858866 0,07928529 ! pigmentation during development GO:0048066 9 9 0,000 0,03858866 0,079197 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03858866 0,07910891 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03858866 0,07902101 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03858866 0,0789333 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03858866 0,0788458 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03858866 0,07875848 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03858866 0,07867136 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03858866 0,07858443 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03858866 0,07849769 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03858866 0,07841114 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03858866 0,07832479 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03858866 0,07823862 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03858866 0,07815265 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03858866 0,07806686 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03858866 0,07798126 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03858866 0,07789585 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03858866 0,07781062 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03858866 0,07772558 ! DNA replication initiation GO:0006270 9 9 0,000 0,03858866 0,07764073 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03858866 0,07755606 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03858866 0,07747158 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03858866 0,07738728 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03858866 0,07730316 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03858866 0,07721923 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03858866 0,07713547 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03858866 0,0770519 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03858866 0,07696851 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03858866 0,07688531 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03858866 0,07680228 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03858866 0,07671943 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03858866 0,07663675 ! collagen catabolic process GO:0030574 9 9 0,000 0,03858866 0,07655426 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03858866 0,07647194 ! purine base metabolic process GO:0006144 9 9 0,000 0,03858866 0,0763898 ! gas transport GO:0015669 9 9 0,000 0,03858866 0,07630784 ! cholesterol efflux GO:0033344 9 9 0,000 0,03858866 0,07622605 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03858866 0,07614444 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03858866 0,076063 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03858866 0,07598174 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03858866 0,07590065 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03858866 0,07581973 ! defense response to virus GO:0051607 9 9 0,000 0,03858866 0,07573899 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03858866 0,07565841 ! actin filament-based movement GO:0030048 9 9 0,000 0,03858866 0,07557801 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03858866 0,07549778 ! muscle system process GO:0003012 72 72 1,000 0,03890719 0,07604024 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03890719 0,07595968 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04278636 0,08344471 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04278636 0,0833565 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04278636 0,08326848 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04278636 0,08318065 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04278636 0,083093 ! neuron maturation GO:0042551 10 10 0,000 0,04278636 0,08300553 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04278636 0,08291825 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04278636 0,08283115 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,04278636 0,08274423 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04278636 0,0826575 ! hormone secretion GO:0046879 10 10 0,000 0,04278636 0,08257095 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04278636 0,08248457 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04278636 0,08239838 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,04278636 0,08231237 ! cAMP metabolic process GO:0046058 10 10 0,000 0,04278636 0,08222654 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04278636 0,08214089 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04278636 0,08205541 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04278636 0,08197012 ! glial cell development GO:0021782 10 10 0,000 0,04278636 0,081885 ! phototransduction GO:0007602 11 10 0,000 0,04278636 0,08180006 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,04278636 0,08171529 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04278636 0,0816307 ! fat cell differentiation GO:0045444 10 10 0,000 0,04278636 0,08154628 ! myoblast differentiation GO:0045445 10 10 0,000 0,04278636 0,08146204 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04278636 0,08137797 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04278636 0,08129408 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04278636 0,08121035 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,04278636 0,0811268 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04278636 0,08104343 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04278636 0,08096022 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04278636 0,08087718 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04278636 0,08079432 ! plasma membrane organization GO:0007009 10 10 0,000 0,04278636 0,08071162 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04278636 0,08062909 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,04278636 0,08054673 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04278636 0,08046454 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04278636 0,08038252 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,04278636 0,08030067 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,04278636 0,08021898 ! exocrine system development GO:0035272 10 10 0,000 0,04278636 0,08013745 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04278636 0,08005609 ! embryo implantation GO:0007566 11 10 0,000 0,04278636 0,0799749 ! regulation of protein binding GO:0043393 11 10 0,000 0,04278636 0,07989387 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04278636 0,07981301 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04278636 0,07973231 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04278636 0,07965177 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04278636 0,0795714 ! protein export from nucleus GO:0006611 10 10 0,000 0,04278636 0,07949118 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04278636 0,07941113 ! cytolysis GO:0019835 10 10 0,000 0,04278636 0,07933124 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04278636 0,07925151 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04278636 0,07917194 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04278636 0,07909253 ! histone deacetylation GO:0016575 10 10 0,000 0,04278636 0,07901328 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04278636 0,07893419 ! gland morphogenesis GO:0022612 10 10 0,000 0,04278636 0,07885525 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04278636 0,07877648 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04278636 0,07869786 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04278636 0,0786194 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04278636 0,07854109 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,04278636 0,07846294 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04278636 0,07838494 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04278636 0,0783071 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04278636 0,07822942 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04278636 0,07815189 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04278636 0,07807451 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04278636 0,07799728 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04278636 0,07792021 ! nerve development GO:0021675 10 10 0,000 0,04278636 0,07784329 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,04278636 0,07776652 ! gut development GO:0048565 10 10 0,000 0,04278636 0,0776899 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04278636 0,07761344 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04278636 0,07753712 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04278636 0,07746096 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04278636 0,07738494 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04278636 0,07730907 ! protein stabilization GO:0050821 10 10 0,000 0,04278636 0,07723335 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,04292151 0,0774015 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,04394864 0,07917629 ! protein secretion GO:0009306 11 11 0,000 0,04696633 0,08453022 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04696633 0,08444775 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04696633 0,08436544 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04696633 0,08428329 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04696633 0,08420131 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04696633 0,08411948 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04696633 0,08403781 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04696633 0,0839563 ! skin development GO:0043588 11 11 0,000 0,04696633 0,08387494 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04696633 0,08379375 ! signal complex assembly GO:0007172 11 11 0,000 0,04696633 0,08371271 ! microtubule-based transport GO:0010970 11 11 0,000 0,04696633 0,08363183 ! endothelial cell migration GO:0043542 11 11 0,000 0,04696633 0,0835511 ! peroxisomal transport GO:0043574 11 11 0,000 0,04696633 0,08347053 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04696633 0,08339012 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04696633 0,08330986 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04696633 0,08322975 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04696633 0,0831498 ! T cell proliferation GO:0042098 11 11 0,000 0,04696633 0,08307 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04696633 0,08299036 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04696633 0,08291086 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04696633 0,08283152 ! spinal cord development GO:0021510 11 11 0,000 0,04696633 0,08275233 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04696633 0,0826733 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04696633 0,08259441 ! digestive system process GO:0022600 11 11 0,000 0,04696633 0,08251567 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04696633 0,08243709 ! fucose metabolic process GO:0006004 11 11 0,000 0,04696633 0,08235865 ! membrane budding GO:0006900 11 11 0,000 0,04696633 0,08228036 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04696633 0,08220222 ! monoamine transport GO:0015844 11 11 0,000 0,04696633 0,08212423 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04696633 0,08204639 ! body fluid secretion GO:0007589 11 11 0,000 0,04696633 0,0819687 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04696633 0,08189115 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04696633 0,08181375 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04696633 0,08173649 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04696633 0,08165938 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04696633 0,08158241 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04696633 0,0815056 ! oogenesis GO:0048477 11 11 0,000 0,04696633 0,08142892 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04696633 0,08135239 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04696633 0,081276 ! vitamin transport GO:0051180 11 11 0,000 0,04696633 0,08119976 ! muscle maintenance GO:0046716 12 11 0,000 0,04696633 0,08112366 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04696633 0,0810477 ! hindbrain development GO:0030902 11 11 0,000 0,04696633 0,08097188 ! steroid catabolic process GO:0006706 11 11 0,000 0,04696633 0,08089621 ! endocrine process GO:0050886 11 11 0,000 0,04696633 0,08082067 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04696633 0,08074528 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04696633 0,08067003 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04696633 0,08059492 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04696633 0,08051995 ! neuron projection development GO:0031175 85 80 1,000 0,04708506 0,08064849 ! MAPKKK cascade GO:0000165 82 81 1,000 0,04814856 0,0823935 ! tube development GO:0035295 83 81 1,000 0,04814856 0,08231707 ! lymphocyte activation GO:0046649 82 81 1,000 0,04814856 0,08224078 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,05030205 0,08583952 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,05112865 0,08716939 ! translational initiation GO:0006413 12 12 0,000 0,05112865 0,08708882 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,05112865 0,08700841 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,05112865 0,08692814 ! initiation of viral infection GO:0019059 12 12 0,000 0,05112865 0,08684803 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,05112865 0,08676805 ! iron ion transport GO:0006826 13 12 0,000 0,05112865 0,08668823 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,05112865 0,08660855 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,05112865 0,08652902 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,05112865 0,08644964 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,05112865 0,0863704 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,05112865 0,08629131 ! collagen metabolic process GO:0032963 12 12 0,000 0,05112865 0,08621236 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,05112865 0,08613355 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,05112865 0,08605489 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,05112865 0,08597638 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,05112865 0,085898 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,05112865 0,08581977 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,05112865 0,08574168 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,05112865 0,08566373 ! actomyosin structure organization GO:0031032 12 12 0,000 0,05112865 0,08558593 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,05112865 0,08550826 ! retinoid metabolic process GO:0001523 12 12 0,000 0,05112865 0,08543074 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,05112865 0,08535336 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,05112865 0,08527612 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,05112865 0,08519901 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,05112865 0,08512205 ! acute-phase response GO:0006953 12 12 0,000 0,05112865 0,08504522 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,05112865 0,08496854 ! vacuolar transport GO:0007034 12 12 0,000 0,05112865 0,08489199 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,05112865 0,08481558 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,05112865 0,0847393 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,05112865 0,08466317 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,05112865 0,08458717 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,05112865 0,08451131 ! male gonad development GO:0008584 12 12 0,000 0,05112865 0,08443558 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,05112865 0,08435999 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,05112865 0,08428453 ! renal system process GO:0003014 12 12 0,000 0,05112865 0,08420921 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,05112865 0,08413402 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,05112865 0,08405897 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,05112865 0,08398405 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,05112865 0,08390927 ! pallium development GO:0021543 13 12 0,000 0,05112865 0,08383461 ! cell fate determination GO:0001709 12 12 0,000 0,05112865 0,0837601 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,05112865 0,08368571 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,05112865 0,08361145 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,05112865 0,08353733 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,05112865 0,08346334 ! detection of light stimulus GO:0009583 13 12 0,000 0,05112865 0,08338948 ! synaptogenesis GO:0007416 12 12 0,000 0,05112865 0,08331574 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,05112865 0,08324214 ! hormone transport GO:0009914 12 12 0,000 0,05112865 0,08316867 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,05112865 0,08309533 ! heme biosynthetic process GO:0006783 12 12 0,000 0,05112865 0,08302212 ! spermatid differentiation GO:0048515 13 12 0,000 0,05112865 0,08294904 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,05112865 0,08287608 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,05112865 0,08280326 ! neural tube closure GO:0001843 13 12 0,000 0,05112865 0,08273056 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,05112865 0,08265799 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,05112865 0,08258555 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,05249025 0,08471061 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,05359713 0,08642127 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,0552734 0,08904622 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,0552734 0,08896845 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,0552734 0,08889082 ! phenol metabolic process GO:0018958 13 13 0,000 0,0552734 0,08881332 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,0552734 0,08873596 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,0552734 0,08865873 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,0552734 0,08858164 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,0552734 0,08850467 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,0552734 0,08842785 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,0552734 0,08835115 ! regeneration GO:0031099 13 13 0,000 0,0552734 0,08827459 ! keratinization GO:0031424 13 13 0,000 0,0552734 0,08819817 ! post-embryonic development GO:0009791 14 13 0,000 0,0552734 0,08812187 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,0552734 0,0880457 ! patterning of blood vessels GO:0001569 13 13 0,000 0,0552734 0,08796967 ! vasculogenesis GO:0001570 13 13 0,000 0,0552734 0,08789377 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,0552734 0,087818 ! regulation of innate immune response GO:0045088 13 13 0,000 0,0552734 0,08774236 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,0552734 0,08766685 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,0552734 0,08759147 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,0552734 0,08751622 ! autophagy GO:0006914 13 13 0,000 0,0552734 0,0874411 ! receptor metabolic process GO:0043112 14 13 0,000 0,0552734 0,08736611 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,0552734 0,08729124 ! ureteric bud development GO:0001657 13 13 0,000 0,0552734 0,08721651 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,0552734 0,0871419 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,0552734 0,08706742 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,0552734 0,08699307 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,0552734 0,08691884 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,0552734 0,08684474 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,0552734 0,08677077 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,0552734 0,08669692 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,0552734 0,0866232 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,0552734 0,0865496 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,0552734 0,08647613 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,0552734 0,08640278 ! vasodilation GO:0042311 14 13 0,000 0,0552734 0,08632956 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,0552734 0,08625646 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,0552734 0,08618349 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,0552734 0,08611063 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,0552734 0,08603791 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,0552734 0,0859653 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,0552734 0,08589282 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,0552734 0,08582046 ! immunoglobulin production GO:0002377 13 13 0,000 0,0552734 0,08574822 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,0552734 0,0856761 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,0552734 0,0856041 ! cell-cell junction organization GO:0045216 13 13 0,000 0,0552734 0,08553223 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,0552734 0,08546047 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,0552734 0,08538884 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,0552734 0,08531732 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,0552734 0,08524593 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,0552734 0,08517465 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,0552734 0,08510349 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,0552734 0,08503245 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,0552734 0,08496154 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,0552734 0,08489073 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,0552734 0,08482005 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,0552734 0,08474948 ! blastocyst development GO:0001824 13 13 0,000 0,0552734 0,08467904 ! telomere organization GO:0032200 13 13 0,000 0,0552734 0,0846087 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,0552734 0,08453849 ! regulation of amine transport GO:0051952 13 13 0,000 0,0552734 0,08446839 ! tissue homeostasis GO:0001894 13 13 0,000 0,0552734 0,08439841 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,0552734 0,08432854 ! DNA replication GO:0006260 91 91 1,000 0,0592559 0,09032971 ! neuron fate commitment GO:0048663 14 14 0,000 0,05940065 0,09047553 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05940065 0,09040082 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05940065 0,09032623 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05940065 0,09025177 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05940065 0,09017743 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05940065 0,09010321 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05940065 0,09002911 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05940065 0,08995513 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05940065 0,08988128 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05940065 0,08980754 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05940065 0,08973393 ! vesicle docking GO:0048278 14 14 0,000 0,05940065 0,08966044 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05940065 0,08958707 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05940065 0,08951381 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05940065 0,08944068 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05940065 0,08936767 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05940065 0,08929478 ! hair cycle GO:0042633 14 14 0,000 0,05940065 0,089222 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05940065 0,08914934 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05940065 0,08907681 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05940065 0,08900439 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05940065 0,08893208 ! lysosome organization GO:0007040 14 14 0,000 0,05940065 0,0888599 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05940065 0,08878783 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05940065 0,08871588 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05940065 0,08864404 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05940065 0,08857233 ! primary neural tube formation GO:0014020 15 14 0,000 0,05940065 0,08850072 ! peptide cross-linking GO:0018149 14 14 0,000 0,05940065 0,08842924 ! regulation of behavior GO:0050795 14 14 0,000 0,05940065 0,08835787 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05940065 0,08828661 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05940065 0,08821547 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05940065 0,08814444 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05940065 0,08807353 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05940065 0,08800273 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05940065 0,08793204 ! collagen fibril organization GO:0030199 14 14 0,000 0,05940065 0,08786147 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05940065 0,08779101 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05940065 0,08772067 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05940065 0,08765044 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05940065 0,08758032 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05940065 0,08751031 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05940065 0,08744041 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05940065 0,08737063 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05940065 0,08730095 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05940065 0,08723139 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,0604119 0,08864581 ! regulation of response to stress GO:0080134 97 94 1,000 0,06274748 0,09199968 ! blood vessel development GO:0001568 95 94 1,000 0,06274748 0,09192655 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06351046 0,09297044 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06351046 0,09289665 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06351046 0,09282298 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,06351046 0,09274943 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06351046 0,09267599 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06351046 0,09260268 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06351046 0,09252947 ! response to vitamin GO:0033273 15 15 0,000 0,06351046 0,09245638 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,06351046 0,09238341 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,06351046 0,09231055 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,06351046 0,09223781 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06351046 0,09216518 ! ovarian follicle development GO:0001541 15 15 0,000 0,06351046 0,09209267 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06351046 0,09202027 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06351046 0,09194798 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,06351046 0,09187581 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06351046 0,09180375 ! heme metabolic process GO:0042168 15 15 0,000 0,06351046 0,0917318 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,06351046 0,09165997 ! chromosome condensation GO:0030261 15 15 0,000 0,06351046 0,09158825 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06351046 0,09151664 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06351046 0,09144514 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,06351046 0,09137376 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06351046 0,09130248 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,06351046 0,09123132 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06351046 0,09116027 ! phospholipid transport GO:0015914 15 15 0,000 0,06351046 0,09108932 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,06351046 0,09101849 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06351046 0,09094777 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06351046 0,09087716 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06351046 0,09080666 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,06351046 0,09073626 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06351046 0,09066598 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06351046 0,09059581 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,06351046 0,09052574 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06351046 0,09045578 ! protein homooligomerization GO:0051260 15 15 0,000 0,06351046 0,09038593 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06351046 0,09031619 ! vasculature development GO:0001944 97 96 1,000 0,0651139 0,09252499 ! endocytosis GO:0006897 99 98 1,000 0,0675105 0,09585659 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,0675105 0,0957828 ! blood circulation GO:0008015 99 98 1,000 0,0675105 0,09570912 GO:0003013|circulatory system process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06760291 0,09576647 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06760291 0,09569291 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06760291 0,09561947 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06760291 0,09554614 ! circadian rhythm GO:0007623 16 16 0,000 0,06760291 0,09547293 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06760291 0,09539982 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06760291 0,09532683 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,06760291 0,09525395 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06760291 0,09518119 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06760291 0,09510853 ! vesicle targeting GO:0006903 17 16 0,000 0,06760291 0,09503598 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06760291 0,09496355 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06760291 0,09489122 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06760291 0,094819 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06760291 0,0947469 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06760291 0,0946749 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06760291 0,09460302 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06760291 0,09453124 ! cell fate specification GO:0001708 16 16 0,000 0,06760291 0,09445957 ! pentose metabolic process GO:0019321 16 16 0,000 0,06760291 0,09438801 ! fatty acid transport GO:0015908 16 16 0,000 0,06760291 0,09431656 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06760291 0,09424521 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06760291 0,09417398 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06760291 0,09410285 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06760291 0,09403183 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06760291 0,09396091 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06760291 0,09389011 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06760291 0,09381941 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06760291 0,09374881 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06760291 0,09367832 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06760291 0,09360794 ! regulation of coagulation GO:0050818 17 16 0,000 0,06760291 0,09353767 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,06993662 0,09669406 ! hemopoiesis GO:0030097 104 100 1,000 0,06993662 0,09662158 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,07167808 0,09895333 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,07167808 0,09887926 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,07167808 0,09880531 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,07167808 0,09873146 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,07167808 0,09865773 ! leukocyte adhesion GO:0007159 17 17 0,000 0,07167808 0,0985841 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,07167808 0,09851059 ! sensory perception of smell GO:0007608 17 17 0,000 0,07167808 0,09843718 ! tissue remodeling GO:0048771 17 17 0,000 0,07167808 0,09836388 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,07167808 0,0982907 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,07167808 0,09821762 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,07167808 0,09814465 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,07167808 0,09807179 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,07167808 0,09799903 ! neural crest cell development GO:0014032 19 17 0,000 0,07167808 0,09792639 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,07167808 0,09785385 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,07167808 0,09778142 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,07167808 0,09770909 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,07167808 0,09763688 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,07167808 0,09756477 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,07167808 0,09749276 ! pigmentation GO:0043473 17 17 0,000 0,07167808 0,09742087 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,07167808 0,09734908 ! adult locomotory behavior GO:0008344 17 17 0,000 0,07167808 0,09727739 ! embryonic organ development GO:0048568 17 17 0,000 0,07167808 0,09720581 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,07167808 0,09713433 ! liver development GO:0001889 17 17 0,000 0,07167808 0,09706296 ! gene silencing GO:0016458 17 17 0,000 0,07167808 0,0969917 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07573602 0,10240754 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,07573602 0,10233247 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07573602 0,1022575 ! meiosis I GO:0007127 18 18 0,000 0,07573602 0,10218264 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07573602 0,10210789 ! membrane docking GO:0022406 18 18 0,000 0,07573602 0,10203325 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,07573602 0,10195872 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07573602 0,10188429 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07573602 0,10180998 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07573602 0,10173577 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07573602 0,10166168 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,07573602 0,10158769 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,07573602 0,10151381 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,07573602 0,10144003 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07573602 0,10136636 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,07573602 0,1012928 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,07573602 0,10121935 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07573602 0,101146 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07573602 0,10107276 ! BMP signaling pathway GO:0030509 18 18 0,000 0,07573602 0,10099963 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,07573602 0,1009266 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07573602 0,10085367 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07977681 0,10615788 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07977681 0,10608129 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07977681 0,1060048 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07977681 0,10592843 ! feeding behavior GO:0007631 19 19 0,000 0,07977681 0,10585217 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07977681 0,10577602 ! peroxisome organization GO:0007031 19 19 0,000 0,07977681 0,10569997 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07977681 0,10562404 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07977681 0,10554822 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07977681 0,1054725 ! metanephros development GO:0001656 19 19 0,000 0,07977681 0,10539689 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07977681 0,10532139 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07977681 0,105246 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07977681 0,10517072 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07977681 0,10509554 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07977681 0,10502047 ! regulation of protein stability GO:0031647 19 19 0,000 0,07977681 0,10494551 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07977681 0,10487066 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07977681 0,10479591 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,07977681 0,10472127 ! eye morphogenesis GO:0048592 19 19 0,000 0,07977681 0,10464674 ! regulation of cell shape GO:0008360 21 19 0,000 0,07977681 0,10457231 ! placenta development GO:0001890 19 19 0,000 0,07977681 0,10449798 ! response to heat GO:0009408 19 19 0,000 0,07977681 0,10442377 ! vesicle localization GO:0051648 20 19 0,000 0,07977681 0,10434965 ! regulation of muscle development GO:0048634 21 20 0,000 0,08380052 0,10953501 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,08380052 0,10945738 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,08380052 0,10937986 ! negative regulation of binding GO:0051100 21 20 0,000 0,08380052 0,10930245 ! organic ether metabolic process GO:0018904 20 20 0,000 0,08380052 0,10922515 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,08380052 0,10914796 ! neural tube development GO:0021915 21 20 0,000 0,08380052 0,10907088 ! nucleus organization GO:0006997 20 20 0,000 0,08380052 0,10899391 ! phagocytosis GO:0006909 21 20 0,000 0,08380052 0,10891704 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08380052 0,10884029 ! protein targeting to membrane GO:0006612 22 20 0,000 0,08380052 0,10876364 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,08380052 0,1086871 ! chromatin remodeling GO:0006338 20 20 0,000 0,08380052 0,10861067 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08380052 0,10853434 ! lipid oxidation GO:0034440 20 20 0,000 0,08380052 0,10845812 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,08380052 0,10838201 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08380052 0,10830601 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08380052 0,10823011 ! RNA modification GO:0009451 20 20 0,000 0,08380052 0,10815432 ! single fertilization GO:0007338 21 20 0,000 0,08380052 0,10807863 ! regulation of B cell activation GO:0050864 20 20 0,000 0,08380052 0,10800305 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,08780723 0,11308786 ! mRNA catabolic process GO:0006402 21 21 0,000 0,08780723 0,11300888 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,08780723 0,11293002 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,08780723 0,11285127 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,08780723 0,11277263 ! Notch signaling pathway GO:0007219 22 21 0,000 0,08780723 0,1126941 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,08780723 0,11261567 ! ear morphogenesis GO:0042471 21 21 0,000 0,08780723 0,11253736 ! organic anion transport GO:0015711 21 21 0,000 0,08780723 0,11245915 ! cholesterol transport GO:0030301 21 21 0,000 0,08780723 0,11238106 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,08780723 0,11230307 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,08780723 0,11222519 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,08780723 0,11214742 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,08780723 0,11206975 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,08780723 0,11199219 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,08780723 0,11191474 ! regulation of proteolysis GO:0030162 21 21 0,000 0,08780723 0,1118374 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,08780723 0,11176017 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,08780723 0,11168304 ! sister chromatid segregation GO:0000819 22 22 0,000 0,09179699 0,11667714 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,09179699 0,11659673 ! regulation of ion transport GO:0043269 22 22 0,000 0,09179699 0,11651643 ! odontogenesis GO:0042476 22 22 0,000 0,09179699 0,11643624 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,09179699 0,11635616 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,09179699 0,11627619 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,09179699 0,11619633 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,09179699 0,11611658 ! ovulation cycle process GO:0022602 22 22 0,000 0,09179699 0,11603694 ! spindle organization GO:0007051 22 22 0,000 0,09179699 0,1159574 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,09179699 0,11587798 ! cell chemotaxis GO:0060326 23 22 0,000 0,09179699 0,11579867 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,09179699 0,11571946 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,09179699 0,11564036 ! male sex differentiation GO:0046661 22 22 0,000 0,09179699 0,11556138 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,09179699 0,11548249 ! biopolymer methylation GO:0043414 22 22 0,000 0,09179699 0,11540372 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,09179699 0,11532505 ! detection of external stimulus GO:0009581 23 22 0,000 0,09179699 0,11524649 ! neuron migration GO:0001764 22 22 0,000 0,09179699 0,11516804 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,09179699 0,1150897 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,09179699 0,11501146 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,09179699 0,11493332 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,09179699 0,1148553 ! aerobic respiration GO:0009060 22 22 0,000 0,09179699 0,11477738 ! cytokine production GO:0001816 22 22 0,000 0,09179699 0,11469956 ! cytokinesis GO:0000910 23 22 0,000 0,09179699 0,11462185 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,09179699 0,11454425 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,09576988 0,11942077 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,09576988 0,11934002 ! viral infectious cycle GO:0019058 23 23 0,000 0,09576988 0,11925939 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,09576988 0,11917886 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,09576988 0,11909844 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,09576988 0,11901813 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,09576988 0,11893793 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,09576988 0,11885784 ! endocrine system development GO:0035270 23 23 0,000 0,09576988 0,11877786 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,09576988 0,11869798 ! female gonad development GO:0008585 23 23 0,000 0,09576988 0,11861821 ! lipid homeostasis GO:0055088 23 23 0,000 0,09576988 0,11853854 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,09576988 0,11845899 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,09576988 0,11837954 ! gliogenesis GO:0042063 24 24 0,000 0,09972597 0,12318697 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,09972597 0,12310446 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09972597 0,12302207 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09972597 0,12293978 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,09972597 0,1228576 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,09972597 0,12277553 ! ovulation cycle GO:0042698 24 24 0,000 0,09972597 0,12269357 ! fertilization GO:0009566 25 24 0,000 0,09972597 0,12261172 ! maintenance of protein location GO:0045185 25 24 0,000 0,09972597 0,12252998 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09972597 0,12244834 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09972597 0,12236682 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,10366533 0,1271159 ! negative regulation of secretion GO:0051048 26 25 0,000 0,10366533 0,12703138 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10366533 0,12694698 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10366533 0,12686268 ! cellular component disassembly GO:0022411 26 25 0,000 0,10366533 0,1267785 ! endosome transport GO:0016197 25 25 0,000 0,10366533 0,12669443 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10366533 0,12661047 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,10366533 0,12652662 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10366533 0,12644288 ! excretion GO:0007588 25 25 0,000 0,10366533 0,12635926 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,10366533 0,12627574 ! gastrulation GO:0007369 25 25 0,000 0,10366533 0,12619234 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10366533 0,12610904 ! regulation of endocytosis GO:0030100 25 25 0,000 0,10366533 0,12602586 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,10366533 0,12594278 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10366533 0,12585981 ! positive regulation of defense response GO:0031349 26 26 0,000 0,10758802 0,13053635 ! glycolysis GO:0006096 26 26 0,000 0,10758802 0,13045047 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,10758802 0,1303647 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,10758802 0,13027905 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,10758802 0,13019351 ! cellular defense response GO:0006968 26 26 0,000 0,10758802 0,13010808 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,10758802 0,13002276 ! regulation of protein secretion GO:0050708 26 26 0,000 0,10758802 0,12993756 ! germ cell development GO:0007281 27 26 0,000 0,10758802 0,12985247 ! pigment metabolic process GO:0042440 26 26 0,000 0,10758802 0,12976748 ! maintenance of location in cell GO:0051651 27 26 0,000 0,10758802 0,12968261 ! chloride transport GO:0006821 27 27 0,000 0,11149411 0,13430304 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,11149411 0,13421531 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,11149411 0,1341277 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,11149411 0,13404021 ! peptide metabolic process GO:0006518 29 27 0,000 0,11149411 0,13395283 ! mesenchymal cell development GO:0014031 29 27 0,000 0,11149411 0,13386557 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,11149411 0,13377841 ! defense response to bacterium GO:0042742 27 27 0,000 0,11149411 0,13369138 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,11149411 0,13360445 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,11149411 0,13351764 ! cell growth GO:0016049 27 27 0,000 0,11149411 0,13343094 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11538367 0,13799618 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11538367 0,13790669 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,11538367 0,13781731 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,11538367 0,13772805 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11538367 0,13763891 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11538367 0,13754988 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,11538367 0,13746096 ! developmental growth GO:0048589 28 28 0,000 0,11538367 0,13737216 ! cartilage development GO:0051216 29 28 0,000 0,11538367 0,13728348 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,11925677 0,14180015 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,11925677 0,14170873 ! leukocyte migration GO:0050900 30 29 0,000 0,11925677 0,14161742 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,11925677 0,14152623 ! antigen processing and presentation GO:0019882 29 29 0,000 0,11925677 0,14143516 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,11925677 0,1413442 ! tRNA processing GO:0008033 29 29 0,000 0,11925677 0,14125336 ! adult behavior GO:0030534 30 29 0,000 0,11925677 0,14116264 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,11925677 0,14107204 ! transition metal ion transport GO:0000041 31 30 0,000 0,12311348 0,14554082 ! RNA catabolic process GO:0006401 30 30 0,000 0,12311348 0,14544753 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,12311348 0,14535435 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,12311348 0,1452613 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,12311348 0,14516836 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,12311348 0,14507554 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,12311348 0,14498284 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,12311348 0,14489026 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,12311348 0,1447978 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,12311348 0,14470545 ! response to temperature stimulus GO:0009266 30 30 0,000 0,12311348 0,14461322 ! regulation of ossification GO:0030278 30 30 0,000 0,12311348 0,14452111 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,12311348 0,14442912 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,12311348 0,14433724 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,12311348 0,14424548 ! vesicle organization GO:0016050 30 30 0,000 0,12311348 0,14415384 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,12311348 0,14406231 ! establishment of organelle localization GO:0051656 31 30 0,000 0,12311348 0,1439709 ! regulation of translational initiation GO:0006446 31 31 0,000 0,12695386 0,14836776 ! membrane fusion GO:0006944 31 31 0,000 0,12695386 0,14827374 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,12695386 0,14817984 ! ion transmembrane transport GO:0034220 31 31 0,000 0,12695386 0,14808605 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,12695386 0,14799239 ! digestion GO:0007586 31 31 0,000 0,12695386 0,14789884 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,12695386 0,14780541 ! regulation of heart contraction GO:0008016 31 31 0,000 0,12695386 0,1477121 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,12695386 0,1476189 ! camera-type eye development GO:0043010 31 31 0,000 0,12695386 0,14752583 ! extracellular matrix organization GO:0030198 31 31 0,000 0,12695386 0,14743287 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,12695386 0,14734003 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,12695386 0,1472473 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,12695386 0,14715469 ! cell redox homeostasis GO:0045454 32 32 0,000 0,13077798 0,15149203 ! glucose catabolic process GO:0006007 32 32 0,000 0,13077798 0,15139687 ! lipid modification GO:0030258 32 32 0,000 0,13077798 0,15130183 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,13077798 0,15120691 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,13077798 0,15111211 ! cell maturation GO:0048469 32 32 0,000 0,13077798 0,15101743 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,13077798 0,15092286 ! kidney development GO:0001822 32 32 0,000 0,13077798 0,15082842 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,13077798 0,15073409 ! maintenance of location GO:0051235 33 32 0,000 0,13077798 0,15063988 ! amino acid transport GO:0006865 33 33 0,000 0,1345859 0,1549293 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,1345859 0,15483259 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,1345859 0,154736 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1345859 0,15463954 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,1345859 0,15454319 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,1345859 0,15444696 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1345859 0,15435085 ! regulation of actin filament length GO:0030832 34 34 0,000 0,1383777 0,15860081 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,1383777 0,15850223 ! response to metal ion GO:0010038 34 34 0,000 0,1383777 0,15840379 ! ear development GO:0043583 34 34 0,000 0,1383777 0,15830546 ! muscle cell differentiation GO:0042692 35 34 0,000 0,1383777 0,15820725 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,1383777 0,15810917 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1383777 0,15801121 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,1383777 0,15791337 ! secondary metabolic process GO:0019748 34 34 0,000 0,1383777 0,15781565 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1383777 0,15771805 ! detection of stimulus GO:0051606 36 34 0,000 0,1383777 0,15762058 ! acute inflammatory response GO:0002526 35 35 0,000 0,14215343 0,16182135 ! regulation of cellular component size GO:0032535 35 35 0,000 0,14215343 0,16172146 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,14215343 0,1616217 ! mesoderm development GO:0007498 35 35 0,000 0,14215343 0,16152205 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,14215343 0,16142253 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,14215343 0,16132313 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,14215343 0,16122386 ! inorganic anion transport GO:0015698 35 35 0,000 0,14215343 0,16112471 ! regulation of immune effector process GO:0002697 35 35 0,000 0,14215343 0,16102567 ! hydrogen transport GO:0006818 36 36 0,000 0,14591317 0,16518303 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,14591317 0,16508162 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,14591317 0,16498035 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,14591317 0,16487919 ! regulation of mitosis GO:0007088 37 36 0,000 0,14591317 0,16477817 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,14591317 0,16467726 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,14591317 0,16457648 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,14591317 0,16447582 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,14591317 0,16437528 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,14591317 0,16427487 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,14591317 0,16417458 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,14591317 0,16407441 ! gonad development GO:0008406 36 36 0,000 0,14591317 0,16397437 ! activation of immune response GO:0002253 36 36 0,000 0,14591317 0,16387445 ! coagulation GO:0050817 39 36 0,000 0,14591317 0,16377464 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,14965697 0,1678745 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,14965697 0,16777238 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,14965697 0,16767039 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,14965697 0,16756853 ! eye development GO:0001654 37 37 0,000 0,14965697 0,16746679 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,14965697 0,16736517 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,14965697 0,16726367 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,14965697 0,1671623 ! adaptive immune response GO:0002250 37 37 0,000 0,14965697 0,16706105 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,15338491 0,17111888 ! neurotransmitter transport GO:0006836 40 38 0,000 0,15338491 0,17101536 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,15338491 0,17091197 ! exocytosis GO:0006887 40 38 0,000 0,15338491 0,1708087 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,15338491 0,17070555 ! urogenital system development GO:0001655 38 38 0,000 0,15338491 0,17060253 ! hexose catabolic process GO:0019320 38 38 0,000 0,15338491 0,17049963 ! RNA elongation GO:0006354 38 38 0,000 0,15338491 0,17039686 ! meiotic cell cycle GO:0051321 38 38 0,000 0,15338491 0,17029421 ! regulation of neurological system process GO:0031644 38 38 0,000 0,15338491 0,17019169 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,15338491 0,17008929 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,15709705 0,17410094 ! hemostasis GO:0007599 42 39 0,000 0,15709705 0,17399631 ! response to unfolded protein GO:0006986 39 39 0,000 0,15709705 0,17389181 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,15709705 0,17378743 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,15709705 0,17368318 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,15709705 0,17357905 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,15709705 0,17347505 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,15709705 0,17337118 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,15709705 0,17326742 ! developmental maturation GO:0021700 39 39 0,000 0,15709705 0,17316379 ! limb development GO:0060173 39 39 0,000 0,15709705 0,17306029 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,16079345 0,17702648 ! DNA catabolic process GO:0006308 41 40 0,000 0,16079345 0,1769208 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,16079345 0,17681523 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,16079345 0,1767098 ! organelle localization GO:0051640 41 40 0,000 0,16079345 0,17660449 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,16447418 0,18053956 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,16447418 0,18043209 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,16447418 0,18032476 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,16447418 0,18021755 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,16447418 0,18011047 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,16447418 0,18000351 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,16447418 0,17989669 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,16813931 0,18379641 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,16813931 0,18368746 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,16813931 0,18357864 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,16813931 0,18346995 ! protein ubiquitination GO:0016567 43 42 0,000 0,16813931 0,18336138 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,16813931 0,18325295 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,16813931 0,18314465 ! forebrain development GO:0030900 43 42 0,000 0,16813931 0,18303647 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,16813931 0,18292842 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,16813931 0,1828205 ! reproductive structure development GO:0048608 43 43 0,000 0,17178888 0,18667861 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,17178888 0,1865686 ! alcohol catabolic process GO:0046164 43 43 0,000 0,17178888 0,18645872 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,17178888 0,18634898 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,17178888 0,18623936 ! humoral immune response GO:0006959 44 44 0,000 0,17542298 0,19006735 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,17542298 0,18995567 ! vitamin metabolic process GO:0006766 44 44 0,000 0,17542298 0,18984413 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,17542298 0,18973272 ! amine biosynthetic process GO:0009309 46 45 0,000 0,17904167 0,19353301 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,17904167 0,19341957 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,17904167 0,19330626 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,17904167 0,19319309 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,17904167 0,19308004 ! protein processing GO:0016485 45 45 0,000 0,17904167 0,19296713 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,18264499 0,19673567 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,18264499 0,19662075 ! tube morphogenesis GO:0035239 47 46 0,000 0,18264499 0,19650597 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,18264499 0,19639132 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,18264499 0,19627681 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,18264499 0,19616243 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,18623303 0,19989952 ! sex differentiation GO:0007548 47 47 0,000 0,18623303 0,19978316 ! amine transport GO:0015837 47 47 0,000 0,18623303 0,19966694 ! rhythmic process GO:0048511 47 47 0,000 0,18623303 0,19955086 ! calcium ion transport GO:0006816 48 48 0,000 0,18980584 0,20326099 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,18980584 0,20314295 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,18980584 0,20302505 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,19336349 0,2067105 ! divalent metal ion transport GO:0070838 49 49 0,000 0,19336349 0,20659067 ! response to nutrient GO:0007584 49 49 0,000 0,19336349 0,20647098 ! response to bacterium GO:0009617 50 49 0,000 0,19336349 0,20635142 ! regulation of ligase activity GO:0051340 50 49 0,000 0,19336349 0,206232 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,19336349 0,20611273 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,19336349 0,20599359 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,19690603 0,20964634 ! negative regulation of transport GO:0051051 51 50 0,000 0,19690603 0,20952529 ! chromatin assembly GO:0031497 50 50 0,000 0,19690603 0,20940439 GO:0006334|nucleosome assembly, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,19690603 0,20928363 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,19690603 0,209163 ! transcription initiation GO:0006352 50 50 0,000 0,19690603 0,20904252 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,19690603 0,20892217 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,20043353 0,21254257 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,20043353 0,21242035 ! positive regulation of immune response GO:0050778 51 51 0,000 0,20043353 0,21229827 ! rRNA metabolic process GO:0016072 51 51 0,000 0,20043353 0,21217633 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,20043353 0,21205453 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,20043353 0,21193287 ! protein maturation GO:0051604 51 51 0,000 0,20043353 0,21181135 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,20394604 0,21539975 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,20394604 0,21527638 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,20394604 0,21515315 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,20394604 0,21503007 ! sodium ion transport GO:0006814 53 53 0,000 0,20744365 0,2185927 ! tRNA metabolic process GO:0006399 53 53 0,000 0,20744365 0,21846779 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,20744365 0,21834303 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,20744365 0,2182184 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,21092639 0,22175547 ! response to virus GO:0009615 54 54 0,000 0,21092639 0,22162904 ! hormone metabolic process GO:0042445 55 54 0,000 0,21092639 0,22150276 ! sulfur metabolic process GO:0006790 55 54 0,000 0,21092639 0,22137661 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,21092639 0,22125062 ! nucleosome organization GO:0034728 55 55 0,000 0,21439434 0,22476039 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,21439434 0,22463261 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,21439434 0,22450498 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,21784755 0,2279915 ! ATP metabolic process GO:0046034 57 57 0,000 0,22128608 0,23145871 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,22128608 0,23132743 ! innate immune response GO:0045087 58 58 0,000 0,22471001 0,23477355 ! dephosphorylation GO:0016311 60 59 0,000 0,22811937 0,23820057 ! carboxylic acid transport GO:0046942 59 59 0,000 0,22811937 0,23806569 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,22811937 0,23793096 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,22811937 0,23779638 ! immune effector process GO:0002252 59 59 0,000 0,22811937 0,23766196 ! potassium ion transport GO:0006813 60 60 0,000 0,23151424 0,24106257 ! protein polymerization GO:0051258 65 60 0,000 0,23151424 0,24092646 ! cellular respiration GO:0045333 62 61 0,000 0,23489468 0,24430637 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,23489468 0,24416858 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,23489468 0,24403094 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,23826074 0,24738848 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,23826074 0,24724918 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,23826074 0,24711004 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,23826074 0,24697106 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,23826074 0,24683223 ! regulation of secretion GO:0051046 65 63 0,000 0,24161248 0,25016394 ! glucose metabolic process GO:0006006 63 63 0,000 0,24161248 0,25002347 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,24161248 0,24988317 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,24161248 0,24974302 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,24494997 0,25305089 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,24494997 0,25290912 ! anion transport GO:0006820 65 65 0,000 0,24827325 0,25619686 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,24827325 0,2560535 ! regulation of hormone levels GO:0010817 66 65 0,000 0,24827325 0,25591029 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,25158239 0,25917627 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,25158239 0,25903148 ! DNA packaging GO:0006323 66 66 0,000 0,25158239 0,25888685 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,25487745 0,26213122 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,25487745 0,26198502 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,25815848 0,26520963 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,25815848 0,26506188 ! sensory perception of sound GO:0007605 71 69 0,000 0,26142555 0,26826686 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,2646787 0,27145401 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,2646787 0,27130303 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,267918 0,27447075 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,267918 0,27431827 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,267918 0,27416595 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,267918 0,27401381 ! secretion by cell GO:0032940 75 72 0,000 0,27114351 0,27715889 ! sensory organ development GO:0007423 72 72 0,000 0,27114351 0,27700526 ! regulation of cytokine production GO:0001817 72 72 0,000 0,27114351 0,27685179 ! electron transport chain GO:0022900 75 74 0,000 0,27755335 0,28323966 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,27755335 0,28308292 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,28073781 0,28617245 ! response to oxidative stress GO:0006979 76 75 0,000 0,28073781 0,28601425 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,28073781 0,28585623 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,28390869 0,2889253 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,28706606 0,29197724 ! microtubule-based movement GO:0007018 82 78 0,000 0,29020997 0,29501212 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,29020997 0,29484949 ! metal ion homeostasis GO:0055065 78 78 0,000 0,29020997 0,29468704 ! regulation of immune response GO:0050776 78 78 0,000 0,29020997 0,29452477 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,29645763 0,30069974 ! lipid catabolic process GO:0016042 82 81 0,000 0,2995615 0,30368088 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,30572956 0,30976338 ! ncRNA processing GO:0034470 83 83 0,000 0,30572956 0,30959318 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,30879387 0,31252449 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,31184511 0,31543937 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,31184511 0,31526634 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,31488332 0,31816335 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,31488332 0,31798902 ! male gamete generation GO:0048232 90 88 0,000 0,32092089 0,32390865 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,32092089 0,32373136 ! chemotaxis GO:0006935 90 89 0,000 0,32392035 0,32657834 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,32392035 0,32639979 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,32690701 0,3292293 ! brain development GO:0007420 91 90 0,000 0,32690701 0,32904949 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,32988091 0,33186164 ! visual perception GO:0007601 93 92 0,000 0,33284211 0,33465794 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,33284211 0,33447547 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,33284211 0,33429319 ! tissue morphogenesis GO:0048729 94 93 0,000 0,33579066 0,3370709 ! epidermis development GO:0008544 94 94 0,000 0,33872661 0,33983295 ! cofactor metabolic process GO:0051186 95 94 0,000 0,33872661 0,33964806 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,35034545 0,35110748 ! regulation of system process GO:0044057 98 98 0,000 0,35034545 0,35091666 ! anti-apoptosis GO:0006916 100 99 0,000 0,35321918 0,3536029 ! ectoderm development GO:0007398 99 99 0,000 0,35321918 0,35341094 ! response to other organism GO:0051707 101 100 0,000 0,35608062 0,35608062