pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6223-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 2,000 2,931E-07 7,052E-04 GO:0046831|regulation of RNA export from nucleus, ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,944E-07 3,542E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 4,149E-07 3,328E-04 ! positive regulation of intracellular transport GO:0032388 37 22 3,000 6,234E-07 3,75E-04 ! ER overload response GO:0006983 12 8 2,000 1,63E-06 7,845E-04 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,313E-05 5,266E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,367E-05 4,697E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 1,601E-05 4,815E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,94E-05 5,185E-03 ! response to UV GO:0009411 104 53 3,000 2,318E-05 5,576E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 2,886E-05 6,313E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,097E-05 6,209E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 3,097E-05 5,731E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,23E-05 5,551E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,796E-05 6,088E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,796E-05 5,708E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,343E-05 6,147E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,343E-05 5,806E-03 ! protein tetramerization GO:0051262 52 24 2,000 5,683E-05 7,196E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 5,867E-05 7,058E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 6,443E-05 7,382E-03 ! myelination GO:0042552 45 25 2,000 6,443E-05 7,046E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 6,443E-05 6,74E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 6,443E-05 6,459E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 6,586E-05 6,338E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 6,586E-05 6,095E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,267E-05 6,476E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 8,157E-05 7,009E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 8,157E-05 6,767E-03 ! spliceosomal snRNP biogenesis GO:0000387 36 27 2,000 8,157E-05 6,542E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 9,115E-05 7,074E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,58E-05 7,203E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,58E-05 6,984E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 9,58E-05 6,779E-03 ! microvillus organization GO:0032528 7 5 1,000 9,58E-05 6,585E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,58E-05 6,402E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 9,58E-05 6,229E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 9,58E-05 6,065E-03 GO:0022011|myelination in the peripheral nervous system, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,014E-04 6,258E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,014E-04 6,101E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 1,125E-04 6,599E-03 GO:0008366|axon ensheathment, ! peripheral nervous system development GO:0007422 64 32 2,000 1,368E-04 7,834E-03 ! negative regulation of growth GO:0045926 155 84 3,000 1,418E-04 7,936E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 1,434E-04 7,841E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 1,434E-04 7,667E-03 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 1,434E-04 7,501E-03 ! male sex determination GO:0030238 15 6 1,000 1,434E-04 7,341E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,434E-04 7,188E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! astrocyte development GO:0014002 15 6 1,000 1,434E-04 7,041E-03 ! Schwann cell development GO:0014044 15 6 1,000 1,434E-04 6,9E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,434E-04 6,765E-03 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 1,000 1,434E-04 6,635E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 1,501E-04 6,814E-03 ! regulation of microtubule-based process GO:0032886 78 35 2,000 1,792E-04 7,986E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,951E-04 8,535E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,951E-04 8,382E-03 ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 2,004E-04 8,457E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,004E-04 8,311E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,004E-04 8,17E-03 ! neuron adhesion GO:0007158 12 7 1,000 2,004E-04 8,034E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,004E-04 7,902E-03 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 2,004E-04 7,775E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,004E-04 7,652E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,004E-04 7,532E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,004E-04 7,416E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,004E-04 7,304E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,004E-04 7,195E-03 ! axonal fasciculation GO:0007413 18 7 1,000 2,004E-04 7,089E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,101E-04 7,326E-03 ! RNA export from nucleus GO:0006405 56 37 2,000 2,118E-04 7,281E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,118E-04 7,178E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,28E-04 7,618E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,295E-04 7,563E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 2,295E-04 7,461E-03 ! regulation of action potential in neuron GO:0019228 73 39 2,000 2,48E-04 7,957E-03 ! interphase GO:0051325 213 98 3,000 2,568E-04 8,131E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,666E-04 8,33E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 2,666E-04 8,223E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,666E-04 8,119E-03 ! astrocyte differentiation GO:0048708 18 8 1,000 2,666E-04 8,018E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 2,666E-04 7,919E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,666E-04 7,822E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,666E-04 7,728E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 2,666E-04 7,636E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,319E-04 9,395E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,421E-04 9,57E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,421E-04 9,46E-03 ! cell proliferation in forebrain GO:0021846 15 9 1,000 3,421E-04 9,352E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,421E-04 9,247E-03 ! cerebral cortex cell migration GO:0021795 15 9 1,000 3,421E-04 9,145E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 3,421E-04 9,044E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,421E-04 8,946E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,421E-04 8,85E-03 ! postreplication repair GO:0006301 22 9 1,000 3,421E-04 8,755E-03 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 3,421E-04 8,663E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 3,421E-04 8,573E-03 ! double-strand break repair GO:0006302 81 44 2,000 3,554E-04 8,816E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,055E-04 9,956E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,055E-04 9,856E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 4,055E-04 9,757E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,267E-04 0,01016509 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 4,267E-04 0,01006543 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,267E-04 9,968E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 4,267E-04 9,872E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 4,267E-04 9,778E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 4,267E-04 9,686E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,267E-04 9,595E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,267E-04 9,506E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 4,267E-04 9,419E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,6E-04 0,01006088 ! regulation of action potential GO:0001508 95 49 2,000 4,889E-04 0,01059654 ! negative regulation of immune system process GO:0002683 95 50 2,000 5,189E-04 0,01114709 ! telencephalon cell migration GO:0022029 20 11 1,000 5,205E-04 0,01108206 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,205E-04 0,01098485 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,205E-04 0,01088933 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,205E-04 0,01079545 ! vasoconstriction GO:0042310 18 11 1,000 5,205E-04 0,01070318 ! regulation of embryonic development GO:0045995 27 11 1,000 5,205E-04 0,01061248 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,501E-04 0,01112198 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 2,000 5,825E-04 0,01167819 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 6,16E-04 0,01224893 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,233E-04 0,0122924 ! virus-host interaction GO:0019048 29 12 1,000 6,233E-04 0,01219246 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,233E-04 0,01209414 ! focal adhesion formation GO:0048041 35 12 1,000 6,233E-04 0,01199738 ! forebrain cell migration GO:0021885 21 12 1,000 6,233E-04 0,01190217 ! histone acetylation GO:0016573 26 12 1,000 6,233E-04 0,01180845 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,233E-04 0,01171619 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 6,233E-04 0,01162537 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cytoskeleton organization GO:0051494 124 54 2,000 6,508E-04 0,01204438 ! nuclear export GO:0051168 97 55 2,000 6,868E-04 0,01261354 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 7,351E-04 0,01339954 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 7,351E-04 0,01329879 ! response to X-ray GO:0010165 25 13 1,000 7,351E-04 0,01319955 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,351E-04 0,01310177 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of DNA repair GO:0006282 21 13 1,000 7,351E-04 0,01300544 ! regulation of cellular pH GO:0030641 22 13 1,000 7,351E-04 0,01291051 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,351E-04 0,01281695 ! positive regulation of cell migration GO:0030335 126 57 2,000 7,625E-04 0,01319864 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,559E-04 0,01470955 ! response to gamma radiation GO:0010332 28 14 1,000 8,559E-04 0,01460523 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,559E-04 0,01450238 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 9,295E-04 0,01563874 ! pituitary gland development GO:0021983 29 15 1,000 9,856E-04 0,01646759 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 9,856E-04 0,01635402 ! G1/S transition checkpoint GO:0031575 40 15 1,000 9,856E-04 0,016242 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,021E-03 0,01671065 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,069E-03 0,01737486 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 1,124E-03 0,01815162 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,124E-03 0,01803061 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,124E-03 0,0179112 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,124E-03 0,01779336 GO:0031114|regulation of microtubule depolymerization, ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 1,124E-03 0,01767707 ! neuron recognition GO:0008038 35 16 1,000 1,124E-03 0,01756228 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,124E-03 0,01744898 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,271E-03 0,01960885 ! inositol metabolic process GO:0006020 28 17 1,000 1,271E-03 0,01948396 ! glial cell development GO:0021782 27 17 1,000 1,271E-03 0,01936064 ! limbic system development GO:0021761 36 17 1,000 1,271E-03 0,01923887 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,271E-03 0,01911863 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,274E-03 0,01903981 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 1,427E-03 0,02119981 ! centrosome cycle GO:0007098 25 18 1,000 1,427E-03 0,02106975 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,427E-03 0,02094128 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,427E-03 0,02081436 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,427E-03 0,02068897 ! axon guidance GO:0007411 139 73 2,000 1,563E-03 0,02252544 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,592E-03 0,02280133 ! cerebral cortex development GO:0021987 36 19 1,000 1,592E-03 0,02266641 ! actin filament bundle formation GO:0051017 42 19 1,000 1,592E-03 0,02253308 ! neuromuscular junction development GO:0007528 34 19 1,000 1,592E-03 0,02240131 ! G1 phase GO:0051318 40 19 1,000 1,592E-03 0,02227107 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,765E-03 0,02455269 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,765E-03 0,02441158 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,765E-03 0,02427208 ! cellular response to starvation GO:0009267 33 20 1,000 1,765E-03 0,02413417 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 1,765E-03 0,02399782 ! diencephalon development GO:0021536 34 20 1,000 1,765E-03 0,023863 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,765E-03 0,02372969 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,765E-03 0,02359786 ! negative regulation of translation GO:0017148 29 20 1,000 1,765E-03 0,02346748 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,765E-03 0,02333854 ! negative regulation of organelle organization GO:0010639 161 78 2,000 1,891E-03 0,02486237 ! protein oligomerization GO:0051259 139 78 2,000 1,891E-03 0,02472724 ! smooth muscle contraction GO:0006939 46 21 1,000 1,947E-03 0,02532546 ! cell aging GO:0007569 44 21 1,000 1,947E-03 0,0251893 ! protein import into nucleus GO:0006606 158 80 2,000 2,033E-03 0,02615851 ! T cell activation GO:0042110 168 81 2,000 2,107E-03 0,02695948 ! nuclear import GO:0051170 161 81 2,000 2,107E-03 0,02681684 ! regulation of neuron differentiation GO:0045664 167 81 2,000 2,107E-03 0,0266757 ! glutamate signaling pathway GO:0007215 41 22 1,000 2,138E-03 0,02692817 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,138E-03 0,02678792 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,138E-03 0,02664913 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,182E-03 0,02705696 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,337E-03 0,02882922 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,337E-03 0,02868213 ! sex determination GO:0007530 47 23 1,000 2,337E-03 0,02853654 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,337E-03 0,02839241 ! synaptic vesicle transport GO:0048489 46 23 1,000 2,337E-03 0,02824974 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,544E-03 0,03060166 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,544E-03 0,03044941 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,544E-03 0,03029867 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,544E-03 0,03014942 ! pallium development GO:0021543 49 24 1,000 2,544E-03 0,03000163 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,544E-03 0,02985528 ! protein localization in nucleus GO:0034504 176 87 2,000 2,582E-03 0,03015683 ! gland development GO:0048732 206 88 2,000 2,667E-03 0,03100071 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,759E-03 0,03191853 ! response to starvation GO:0042594 42 25 1,000 2,759E-03 0,03176581 ! negative regulation of cell development GO:0010721 73 25 1,000 2,759E-03 0,03161455 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,759E-03 0,03146472 ! somitogenesis GO:0001756 43 25 1,000 2,759E-03 0,0313163 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,759E-03 0,03116927 ! ossification GO:0001503 188 90 2,000 2,843E-03 0,03195905 ! bone development GO:0060348 189 91 2,000 2,933E-03 0,03282114 ! microtubule organizing center organization GO:0031023 39 26 1,000 2,983E-03 0,03323028 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,983E-03 0,03307714 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,983E-03 0,03292541 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 2,983E-03 0,03277507 ! regulation of membrane potential GO:0042391 164 93 2,000 3,119E-03 0,03410825 ! protein amino acid acylation GO:0043543 55 27 1,000 3,215E-03 0,03500569 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,215E-03 0,03484801 ! base-excision repair GO:0006284 41 27 1,000 3,215E-03 0,03469174 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,215E-03 0,03453687 ! mRNA transport GO:0051028 169 96 2,000 3,411E-03 0,03647445 ! dendrite development GO:0016358 59 28 1,000 3,456E-03 0,03678976 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,456E-03 0,03662769 ! regulation of pH GO:0006885 43 29 1,000 3,704E-03 0,03908901 ! skeletal muscle tissue development GO:0007519 186 99 2,000 3,719E-03 0,03907742 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 2,000 3,826E-03 0,04002106 ! cell junction assembly GO:0034329 78 30 1,000 3,961E-03 0,04125351 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 3,961E-03 0,0410757 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,961E-03 0,04089941 ! regulation of B cell activation GO:0050864 50 30 1,000 3,961E-03 0,04072462 ! response to ionizing radiation GO:0010212 65 32 1,000 4,498E-03 0,04605093 ! regulation of axonogenesis GO:0050770 75 32 1,000 4,498E-03 0,0458558 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,498E-03 0,04566232 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,778E-03 0,04830614 ! glial cell differentiation GO:0010001 63 34 1,000 5,067E-03 0,05100718 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,067E-03 0,05079465 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,363E-03 0,05354112 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,363E-03 0,05331988 ! telencephalon development GO:0021537 68 35 1,000 5,363E-03 0,05310045 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,363E-03 0,05288283 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,363E-03 0,05266698 ! cell junction organization GO:0034330 86 36 1,000 5,667E-03 0,05542611 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,667E-03 0,05520171 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 5,979E-03 0,05800335 ! glycogen metabolic process GO:0005977 61 37 1,000 5,979E-03 0,0577704 ! regulation of neuron projection development GO:0010975 91 38 1,000 6,298E-03 0,06061326 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,298E-03 0,06037177 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,298E-03 0,0601322 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 6,298E-03 0,05989453 ! glucan metabolic process GO:0044042 62 38 1,000 6,298E-03 0,05965872 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 6,625E-03 0,06251041 ! learning GO:0007612 77 39 1,000 6,625E-03 0,06226623 ! segmentation GO:0035282 67 39 1,000 6,625E-03 0,06202395 ! gliogenesis GO:0042063 88 41 1,000 7,302E-03 0,06809468 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,302E-03 0,06783176 ! T cell differentiation GO:0030217 81 41 1,000 7,302E-03 0,06757087 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,302E-03 0,06731198 ! polyol metabolic process GO:0019751 66 41 1,000 7,302E-03 0,06705506 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 7,652E-03 0,06999855 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 7,652E-03 0,06973341 ! regulation of tube size GO:0035150 71 42 1,000 7,652E-03 0,06947026 GO:0050880|regulation of blood vessel size, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 7,652E-03 0,06920909 ! neuron migration GO:0001764 79 42 1,000 7,652E-03 0,06894988 ! energy reserve metabolic process GO:0006112 74 43 1,000 8,009E-03 0,07189811 ! glucose transport GO:0015758 65 43 1,000 8,009E-03 0,07163083 ! hexose transport GO:0008645 67 44 1,000 8,373E-03 0,07461307 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 107 44 1,000 8,373E-03 0,07433775 ! negative regulation of cell migration GO:0030336 115 46 1,000 9,124E-03 0,08070599 ! positive regulation of protein transport GO:0051222 72 46 1,000 9,124E-03 0,08041036 ! positive regulation of DNA binding GO:0043388 73 47 1,000 9,51E-03 0,08350897 ! vascular process in circulatory system GO:0003018 80 47 1,000 9,51E-03 0,0832053 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,904E-03 0,08633401 ! mitochondrial transport GO:0006839 82 48 1,000 9,904E-03 0,08602233 ! activation of caspase activity GO:0006919 84 48 1,000 9,904E-03 0,0857129 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 9,904E-03 0,08540569 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01030428 0,08854321 ! endocrine system development GO:0035270 104 49 1,000 0,01030428 0,08822811 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,01071201 0,09139392 ! histone modification GO:0016570 91 50 1,000 0,01071201 0,09107097 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01071201 0,0907503 ! positive regulation of binding GO:0051099 78 51 1,000 0,01112678 0,09393342 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01112678 0,09360499 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01154855 0,09681468 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01154855 0,09647851 ! synapse organization GO:0050808 85 52 1,000 0,01154855 0,09614468 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01241291 0,10298437 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,01241291 0,10263047 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01285541 0,10592504 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01285541 0,10556352 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01285541 0,10520446 ! aging GO:0007568 103 55 1,000 0,01285541 0,10484783 ! heart morphogenesis GO:0003007 97 55 1,000 0,01285541 0,10449362 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01285541 0,10414179 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,01285541 0,10379232 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01330472 0,10706071 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01330472 0,10670384 ! muscle fiber development GO:0048747 112 57 1,000 0,0137608 0,10999496 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,0137608 0,10963073 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,0142236 0,11294385 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01550971 0,12275123 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01550971 0,12234877 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01550971 0,12194893 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01550971 0,12155171 ! neuron fate determination GO:0048664 7 5 0,000 0,01550971 0,12115706 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01550971 0,12076496 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01550971 0,1203754 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01550971 0,11998834 ! polyol transport GO:0015791 12 5 0,000 0,01550971 0,11960376 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01550971 0,11922164 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01550971 0,11884195 ! response to superoxide GO:0000303 10 5 0,000 0,01550971 0,11846468 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01550971 0,11808979 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01550971 0,11771727 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01550971 0,11734709 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01550971 0,11697923 ! female meiosis GO:0007143 7 5 0,000 0,01550971 0,11661367 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01550971 0,11625039 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01550971 0,11588936 ! cobalt ion transport GO:0006824 11 5 0,000 0,01550971 0,11553057 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01550971 0,11517399 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01550971 0,11481961 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01550971 0,1144674 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01550971 0,11411735 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01550971 0,11376943 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01550971 0,11342363 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01550971 0,11307992 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01550971 0,11273829 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01550971 0,11239872 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01550971 0,11206118 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01550971 0,11172567 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01550971 0,11139216 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01550971 0,11106064 ! negative chemotaxis GO:0050919 14 5 0,000 0,01550971 0,11073108 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01550971 0,11040347 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01550971 0,1100778 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01550971 0,10975404 ! behavioral response to pain GO:0048266 9 5 0,000 0,01550971 0,10943218 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01550971 0,1091122 ! Notch receptor processing GO:0007220 8 5 0,000 0,01550971 0,10879409 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01550971 0,10847783 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01550971 0,1081634 ! micturition GO:0060073 9 5 0,000 0,01550971 0,10785079 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01550971 0,10753998 ! copulation GO:0007620 9 5 0,000 0,01550971 0,10723096 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01550971 0,10692371 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01550971 0,10661821 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01550971 0,10631445 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01550971 0,10601243 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01550971 0,10571211 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01550971 0,10541348 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01550971 0,10511655 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01550971 0,10482127 ! grooming behavior GO:0007625 6 5 0,000 0,01550971 0,10452766 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01550971 0,10423568 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01550971 0,10394533 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01550971 0,10365659 ! response to protozoan GO:0001562 10 5 0,000 0,01550971 0,10336946 ! lymph vessel development GO:0001945 10 5 0,000 0,01550971 0,10308391 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01550971 0,10279993 ! endochondral ossification GO:0001958 16 5 0,000 0,01550971 0,10251751 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01550971 0,10223664 ! parathyroid gland development GO:0060017 13 5 0,000 0,01550971 0,10195731 ! anagen GO:0042640 6 5 0,000 0,01550971 0,10167949 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01550971 0,10140319 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01550971 0,10112838 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01550971 0,10085506 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01550971 0,10058322 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01550971 0,10031283 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01550971 0,1000439 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01550971 0,0997764 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01550971 0,09951033 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01550971 0,09924567 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01550971 0,09898242 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01550971 0,09872057 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01550971 0,09846009 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01550971 0,09820098 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01550971 0,09794324 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01550971 0,09768684 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01550971 0,09743178 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01550971 0,09717806 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01550971 0,09692565 ! histidine catabolic process GO:0006548 6 5 0,000 0,01550971 0,09667454 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01550971 0,09642474 ! valine metabolic process GO:0006573 10 5 0,000 0,01550971 0,09617622 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01550971 0,09592898 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01550971 0,09568301 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01550971 0,0954383 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01550971 0,09519483 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01550971 0,0949526 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01550971 0,09471161 ! polyol catabolic process GO:0046174 7 5 0,000 0,01550971 0,09447183 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01550971 0,09423327 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01550971 0,0939959 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01550971 0,09375973 ! muscle cell migration GO:0014812 8 5 0,000 0,01550971 0,09352475 ! mitochondrial fission GO:0000266 8 5 0,000 0,01550971 0,09329093 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01550971 0,09305829 ! mRNA transcription GO:0009299 9 5 0,000 0,01550971 0,0928268 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01550971 0,09259646 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01550971 0,09236726 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01550971 0,09213919 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01550971 0,09191225 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01550971 0,09168642 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01550971 0,0914617 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01550971 0,09123808 ! response to food GO:0032094 6 5 0,000 0,01550971 0,09101555 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01550971 0,0907941 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01550971 0,09057372 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01550971 0,09035442 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01550971 0,09013617 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01550971 0,08991897 ! forebrain neuron development GO:0021884 13 5 0,000 0,01550971 0,08970282 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01550971 0,08948771 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01550971 0,08927362 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01550971 0,08906056 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01550971 0,08884851 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01550971 0,08863747 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01550971 0,08842743 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01550971 0,08821838 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01550971 0,08801032 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01550971 0,08780323 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01550971 0,08759712 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01550971 0,08739198 ! basic amino acid transport GO:0015802 11 5 0,000 0,01550971 0,08718779 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01550971 0,08698455 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01550971 0,08678226 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01550971 0,08658091 ! depyrimidination GO:0045008 10 5 0,000 0,01550971 0,08638049 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01550971 0,086181 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01550971 0,08598243 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01550971 0,08578477 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01550971 0,08558801 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01550971 0,08539216 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01550971 0,0851972 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01550971 0,08500313 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01550971 0,08480994 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01550971 0,08461763 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01550971 0,08442618 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01550971 0,08423561 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01550971 0,08404589 ! response to arsenic GO:0046685 10 5 0,000 0,01550971 0,08385702 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01550971 0,083669 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01550971 0,08348182 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01550971 0,08329548 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01550971 0,08310996 ! response to cadmium ion GO:0046686 7 5 0,000 0,01550971 0,08292527 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01550971 0,0827414 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01550971 0,08255835 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01550971 0,0823761 ! decidualization GO:0046697 11 5 0,000 0,01550971 0,08219466 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01550971 0,08201401 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01550971 0,08183415 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01550971 0,08165508 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01550971 0,0814768 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01550971 0,08129929 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01550971 0,08112255 ! neural tube patterning GO:0021532 7 5 0,000 0,01550971 0,08094658 ! embryonic cleavage GO:0040016 6 5 0,000 0,01550971 0,08077137 ! peroxisome fission GO:0016559 5 5 0,000 0,01550971 0,08059692 ! histone demethylation GO:0016577 10 5 0,000 0,01550971 0,08042322 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01550971 0,08025027 ! mitotic recombination GO:0006312 9 5 0,000 0,01550971 0,08007806 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01550971 0,07990658 ! metaphase plate congression GO:0051310 7 5 0,000 0,01550971 0,07973584 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01550971 0,07956583 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01550971 0,07939654 ! enteric nervous system development GO:0048484 8 5 0,000 0,01550971 0,07922797 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01550971 0,07906011 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01550971 0,07889297 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01550971 0,07872653 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01550971 0,07856079 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01550971 0,07839574 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01550971 0,07823139 ! plasminogen activation GO:0031639 5 5 0,000 0,01550971 0,07806773 ! B cell homeostasis GO:0001782 13 5 0,000 0,01550971 0,07790475 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01550971 0,07774245 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01550971 0,07758082 ! metaphase GO:0051323 8 5 0,000 0,01550971 0,07741986 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01550971 0,07725957 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01550971 0,07709995 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01550971 0,07694098 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01550971 0,07678266 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01550971 0,076625 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01550971 0,07646798 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01550971 0,0763116 ! response to redox state GO:0051775 5 5 0,000 0,01550971 0,07615586 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01550971 0,07600076 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01550971 0,07584629 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01550971 0,07569244 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01550971 0,07553922 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01550971 0,07538661 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01550971 0,07523462 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01550971 0,07508325 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01550971 0,07493248 ! striatum development GO:0021756 9 5 0,000 0,01550971 0,07478231 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01550971 0,07463275 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01550971 0,07448378 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01550971 0,07433541 ! glial cell migration GO:0008347 11 5 0,000 0,01550971 0,07418762 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01550971 0,07404042 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01550971 0,07389381 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01550971 0,07374777 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01550971 0,07360231 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01550971 0,07345743 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01550971 0,07331311 ! neuroprotection GO:0043526 6 5 0,000 0,01550971 0,07316936 ! neural plate development GO:0001840 8 5 0,000 0,01550971 0,07302617 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01550971 0,07288354 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01550971 0,07274147 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01550971 0,07259995 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01550971 0,07245898 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01550971 0,07231855 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01550971 0,07217867 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01550971 0,07203933 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01550971 0,07190053 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01550971 0,07176226 ! spindle assembly GO:0051225 6 5 0,000 0,01550971 0,07162452 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01550971 0,07148731 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01550971 0,07135062 ! drug metabolic process GO:0017144 6 5 0,000 0,01550971 0,07121445 ! stem cell division GO:0017145 11 5 0,000 0,01550971 0,07107881 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01550971 0,07094368 ! organ regeneration GO:0031100 7 5 0,000 0,01550971 0,07080906 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01550971 0,07067495 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01550971 0,07054135 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01550971 0,07040825 ! viral reproductive process GO:0022415 126 62 1,000 0,01614115 0,07313672 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,01663689 0,07524127 ! actin filament organization GO:0007015 148 66 1,000 0,01816267 0,08198757 ! cell projection assembly GO:0030031 120 66 1,000 0,01816267 0,08183403 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01858298 0,0835713 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01858298 0,08341538 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01858298 0,08326004 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01858298 0,08310529 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01858298 0,0829511 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01858298 0,08279749 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01858298 0,08264444 ! sleep GO:0030431 13 6 0,000 0,01858298 0,08249196 ! response to oxygen radical GO:0000305 11 6 0,000 0,01858298 0,08234004 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01858298 0,08218868 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01858298 0,08203788 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01858298 0,08188763 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01858298 0,08173792 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01858298 0,08158877 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01858298 0,08144015 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01858298 0,08129208 ! forebrain regionalization GO:0021871 8 6 0,000 0,01858298 0,08114454 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01858298 0,08099754 ! male meiosis GO:0007140 7 6 0,000 0,01858298 0,08085107 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01858298 0,08070513 ! response to zinc ion GO:0010043 9 6 0,000 0,01858298 0,08055972 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01858298 0,08041483 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01858298 0,08027046 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01858298 0,0801266 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01858298 0,07998326 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01858298 0,07984044 ! malate metabolic process GO:0006108 11 6 0,000 0,01858298 0,07969812 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01858298 0,07955631 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01858298 0,079415 ! protein refolding GO:0042026 15 6 0,000 0,01858298 0,07927419 ! opsonization GO:0008228 8 6 0,000 0,01858298 0,07913388 ! mating behavior GO:0007617 7 6 0,000 0,01858298 0,07899407 ! neuron remodeling GO:0016322 15 6 0,000 0,01858298 0,07885475 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01858298 0,07871592 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01858298 0,07857758 ! equilibrioception GO:0050957 14 6 0,000 0,01858298 0,07843973 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01858298 0,07830235 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01858298 0,07816546 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01858298 0,07802905 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01858298 0,07789311 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01858298 0,07775764 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01858298 0,07762265 ! toxin metabolic process GO:0009404 11 6 0,000 0,01858298 0,07748812 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01858298 0,07735405 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01858298 0,07722046 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01858298 0,07708732 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01858298 0,07695464 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01858298 0,07682241 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01858298 0,07669064 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01858298 0,07655932 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01858298 0,07642845 ! thymic T cell selection GO:0045061 12 6 0,000 0,01858298 0,07629803 ! protein lipoylation GO:0009249 10 6 0,000 0,01858298 0,07616805 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01858298 0,07603851 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01858298 0,07590941 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01858298 0,07578075 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01858298 0,07565253 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01858298 0,07552474 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01858298 0,07539738 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01858298 0,07527044 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01858298 0,07514394 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01858298 0,07501786 ! hyperosmotic response GO:0006972 9 6 0,000 0,01858298 0,0748922 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01858298 0,07476696 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01858298 0,07464214 ! urea metabolic process GO:0019627 7 6 0,000 0,01858298 0,07451774 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01858298 0,07439375 ! neutrophil activation GO:0042119 8 6 0,000 0,01858298 0,07427017 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01858298 0,074147 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01858298 0,07402424 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01858298 0,07390189 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01858298 0,07377994 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01858298 0,07365839 ! neuron apoptosis GO:0051402 9 6 0,000 0,01858298 0,07353724 ! nucleoside salvage GO:0043174 9 6 0,000 0,01858298 0,07341649 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01858298 0,07329614 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01858298 0,07317618 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01858298 0,07305661 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01858298 0,07293743 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01858298 0,07281864 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01858298 0,07270023 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01858298 0,07258221 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01858298 0,07246458 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01858298 0,07234732 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01858298 0,07223044 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01858298 0,07211394 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01858298 0,07199782 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01858298 0,07188206 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01858298 0,07176668 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01858298 0,07165167 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01858298 0,07153703 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01858298 0,07142275 ! neural nucleus development GO:0048857 14 6 0,000 0,01858298 0,07130884 ! response to UV-C GO:0010225 11 6 0,000 0,01858298 0,07119529 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01858298 0,0710821 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01858298 0,07096928 ! interaction with symbiont GO:0051702 13 6 0,000 0,01858298 0,0708568 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01858298 0,07074469 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01858298 0,07063293 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01858298 0,07052152 ! response to copper ion GO:0046688 10 6 0,000 0,01858298 0,07041046 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01858298 0,07029975 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01858298 0,07018939 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01858298 0,07007938 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01858298 0,06996971 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01858298 0,06986038 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01858298 0,06975139 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01858298 0,06964275 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01858298 0,06953444 ! hair follicle maturation GO:0048820 7 6 0,000 0,01858298 0,06942647 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01858298 0,06931883 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01858298 0,06921152 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01858298 0,06910455 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01858298 0,06899791 ! subpallium development GO:0021544 10 6 0,000 0,01858298 0,06889159 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01858298 0,06878561 ! histone ubiquitination GO:0016574 8 6 0,000 0,01858298 0,06867994 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01858298 0,06857461 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01858298 0,06846959 ! G2 phase GO:0051319 16 6 0,000 0,01858298 0,0683649 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01858298 0,06826052 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01858298 0,06815647 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01858298 0,06805273 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01858298 0,06794931 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01858298 0,0678462 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01858298 0,0677434 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01858298 0,06764091 ! receptor internalization GO:0031623 10 6 0,000 0,01858298 0,06753874 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01858298 0,06743687 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01858298 0,06733531 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01858298 0,06723405 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01858298 0,0671331 ! protein deubiquitination GO:0016579 14 6 0,000 0,01858298 0,06703245 ! protein destabilization GO:0031648 9 6 0,000 0,01858298 0,0669321 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01858298 0,06683205 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01858298 0,0667323 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01858298 0,06663285 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01858298 0,0665337 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01858298 0,06643483 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01858298 0,06633627 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01858298 0,06623799 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01858298 0,06614001 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01858298 0,06604231 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01858298 0,0659449 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01858298 0,06584778 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01858298 0,06575095 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01858298 0,0656544 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01858298 0,06555813 ! catecholamine transport GO:0051937 9 6 0,000 0,01858298 0,06546214 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01858298 0,06536644 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01858298 0,06527101 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01858298 0,06517587 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01858298 0,065081 ! maternal placenta development GO:0001893 12 6 0,000 0,01858298 0,0649864 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01858298 0,06489208 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01858298 0,06479803 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01858298 0,06470426 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01858298 0,06461076 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01858298 0,06451752 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01858298 0,06442456 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,01868396 0,06468145 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,01868396 0,06458852 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01868396 0,06449585 ! lung development GO:0030324 144 67 1,000 0,01868396 0,06440345 ! chromosome segregation GO:0007059 113 67 1,000 0,01868396 0,06431131 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01868396 0,06421944 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,01921153 0,06593858 ! viral reproduction GO:0016032 134 68 1,000 0,01921153 0,06584465 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01921153 0,06575099 ! respiratory tube development GO:0030323 150 70 1,000 0,02028534 0,06932745 ! B cell activation GO:0042113 160 71 1,000 0,02083149 0,07109299 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02138374 0,07287433 ! carbohydrate transport GO:0008643 110 72 1,000 0,02138374 0,07277126 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,02138374 0,07266847 ! respiratory system development GO:0060541 153 72 1,000 0,02138374 0,07256598 ! tRNA transcription GO:0009304 14 7 0,000 0,02164675 0,07335504 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02164675 0,07325187 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02164675 0,07314898 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02164675 0,07304639 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02164675 0,07294408 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02164675 0,07284206 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02164675 0,07274033 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02164675 0,07263888 ! prostate gland development GO:0030850 13 7 0,000 0,02164675 0,07253771 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02164675 0,07243682 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02164675 0,07233622 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02164675 0,07223589 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02164675 0,07213584 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02164675 0,07203607 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02164675 0,07193657 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02164675 0,07183735 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02164675 0,0717384 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02164675 0,07163972 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02164675 0,07154131 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02164675 0,07144318 ! glycolipid transport GO:0046836 10 7 0,000 0,02164675 0,07134531 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02164675 0,07124771 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02164675 0,07115038 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02164675 0,07105331 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02164675 0,07095651 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02164675 0,07085997 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02164675 0,07076369 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02164675 0,07066767 ! mRNA stabilization GO:0048255 18 7 0,000 0,02164675 0,07057192 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02164675 0,07047642 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02164675 0,07038118 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02164675 0,0702862 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02164675 0,07019148 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02164675 0,07009701 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02164675 0,07000279 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02164675 0,06990883 ! lipoprotein transport GO:0042953 14 7 0,000 0,02164675 0,06981512 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02164675 0,06972165 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02164675 0,06962844 ! rhythmic behavior GO:0007622 15 7 0,000 0,02164675 0,06953548 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02164675 0,06944277 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02164675 0,0693503 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02164675 0,06925808 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02164675 0,0691661 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02164675 0,06907437 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02164675 0,06898288 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02164675 0,06889164 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02164675 0,06880063 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02164675 0,06870986 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02164675 0,06861934 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02164675 0,06852905 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02164675 0,068439 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02164675 0,06834918 ! spinal cord patterning GO:0021511 13 7 0,000 0,02164675 0,0682596 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02164675 0,06817026 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02164675 0,06808115 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02164675 0,06799227 ! adrenal gland development GO:0030325 17 7 0,000 0,02164675 0,06790362 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02164675 0,0678152 ! ovulation GO:0030728 9 7 0,000 0,02164675 0,06772702 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02164675 0,06763906 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02164675 0,06755133 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02164675 0,06746383 ! microtubule nucleation GO:0007020 20 7 0,000 0,02164675 0,06737655 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02164675 0,0672895 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02164675 0,06720268 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02164675 0,06711608 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02164675 0,0670297 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02164675 0,06694354 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02164675 0,06685761 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02164675 0,06677189 ! galactose metabolic process GO:0006012 13 7 0,000 0,02164675 0,0666864 ! vesicle fusion GO:0006906 17 7 0,000 0,02164675 0,06660112 ! response to dietary excess GO:0002021 8 7 0,000 0,02164675 0,06651606 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02164675 0,06643122 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02164675 0,06634659 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02164675 0,06626218 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02164675 0,06617799 ! organ growth GO:0035265 15 7 0,000 0,02164675 0,06609401 ! purine salvage GO:0043101 10 7 0,000 0,02164675 0,06601024 ! nucleoside transport GO:0015858 8 7 0,000 0,02164675 0,06592668 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02164675 0,06584333 ! parturition GO:0007567 14 7 0,000 0,02164675 0,0657602 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02164675 0,06567727 ! rRNA modification GO:0000154 14 7 0,000 0,02164675 0,06559455 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02164675 0,06551205 ! spindle checkpoint GO:0031577 15 7 0,000 0,02164675 0,06542974 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02164675 0,06534765 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02164675 0,06526576 ! macrophage differentiation GO:0030225 11 7 0,000 0,02164675 0,06518408 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02164675 0,0651026 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02164675 0,06502132 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02164675 0,06494024 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02164675 0,06485937 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02164675 0,0647787 ! fibrinolysis GO:0042730 10 7 0,000 0,02164675 0,06469823 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02164675 0,06461796 ! eating behavior GO:0042755 7 7 0,000 0,02164675 0,06453789 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02164675 0,06445801 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02164675 0,06437834 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02164675 0,06429886 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02164675 0,06421958 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02164675 0,06414049 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02164675 0,06406159 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02164675 0,06398289 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02164675 0,06390439 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02164675 0,06382607 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02164675 0,06374795 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02164675 0,06367002 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02164675 0,06359228 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02164675 0,06351473 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02164675 0,06343736 ! regulation of meiosis GO:0040020 12 7 0,000 0,02164675 0,06336019 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02164675 0,0632832 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02164675 0,0632064 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02164675 0,06312979 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02164675 0,06305336 ! transcription termination GO:0006353 13 7 0,000 0,02164675 0,06297712 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02164675 0,06290106 ! anaphase GO:0051322 17 7 0,000 0,02164675 0,06282518 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02164675 0,06274949 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02164675 0,06267398 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02164675 0,06259865 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02164675 0,0625235 ! diuresis GO:0030146 12 7 0,000 0,02164675 0,06244853 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02164675 0,06237374 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02164675 0,06229913 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02164675 0,0622247 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02164675 0,06215045 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02164675 0,06207637 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02164675 0,06200247 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02164675 0,06192875 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02164675 0,0618552 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02164675 0,06178182 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02164675 0,06170862 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02164675 0,06163559 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02164675 0,06156274 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02164675 0,06149005 ! lymph node development GO:0048535 10 7 0,000 0,02164675 0,06141754 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02164675 0,0613452 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02164675 0,06127303 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02164675 0,06120103 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02164675 0,0611292 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02164675 0,06105753 ! adult feeding behavior GO:0008343 9 7 0,000 0,02164675 0,06098604 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02164675 0,06091471 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02164675 0,06084355 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02164675 0,06077255 ! muscle adaptation GO:0043500 14 7 0,000 0,02164675 0,06070172 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02164675 0,06063105 ! retina homeostasis GO:0001895 12 7 0,000 0,02164675 0,06056055 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02164675 0,06049022 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02164675 0,06042004 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02164675 0,06035003 ! protein prenylation GO:0018342 18 7 0,000 0,02164675 0,06028018 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02164675 0,06021049 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02164675 0,06014097 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02164675 0,0600716 ! learning or memory GO:0007611 147 73 1,000 0,02194206 0,06082095 ! regulation of blood pressure GO:0008217 125 73 1,000 0,02194206 0,06075096 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02250639 0,06224182 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02250639 0,06217036 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,02307671 0,06367267 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02307671 0,06359973 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02307671 0,06352697 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02365297 0,0650389 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02423511 0,06656357 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02470106 0,06776595 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02470106 0,06768877 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02470106 0,06761176 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02470106 0,06753493 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02470106 0,06745828 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02470106 0,06738179 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02470106 0,06730548 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02470106 0,06722934 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02470106 0,06715338 ! meiotic prophase I GO:0007128 13 8 0,000 0,02470106 0,06707759 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02470106 0,06700196 ! oligopeptide transport GO:0006857 15 8 0,000 0,02470106 0,06692651 ! UTP metabolic process GO:0046051 8 8 0,000 0,02470106 0,06685123 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02470106 0,06677611 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02470106 0,06670117 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02470106 0,06662639 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02470106 0,06655178 ! succinate metabolic process GO:0006105 14 8 0,000 0,02470106 0,06647734 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02470106 0,06640306 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02470106 0,06632895 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02470106 0,06625501 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02470106 0,06618123 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02470106 0,06610761 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02470106 0,06603416 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02470106 0,06596087 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02470106 0,06588774 ! reflex GO:0060004 16 8 0,000 0,02470106 0,06581477 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02470106 0,06574197 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02470106 0,06566933 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02470106 0,06559684 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02470106 0,06552452 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02470106 0,06545236 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02470106 0,06538035 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02470106 0,06530851 ! pigment granule organization GO:0048753 16 8 0,000 0,02470106 0,06523682 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02470106 0,06516529 ! histidine metabolic process GO:0006547 16 8 0,000 0,02470106 0,06509391 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02470106 0,06502269 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02470106 0,06495163 ! glycine catabolic process GO:0006546 13 8 0,000 0,02470106 0,06488072 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02470106 0,06480997 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02470106 0,06473937 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02470106 0,06466892 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02470106 0,06459863 ! melanin metabolic process GO:0006582 15 8 0,000 0,02470106 0,06452849 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02470106 0,0644585 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02470106 0,06438867 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02470106 0,06431898 ! macrophage activation GO:0042116 12 8 0,000 0,02470106 0,06424945 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02470106 0,06418007 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02470106 0,06411083 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02470106 0,06404175 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02470106 0,06397281 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02470106 0,06390402 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02470106 0,06383538 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02470106 0,06376689 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02470106 0,06369854 ! osteoblast development GO:0002076 16 8 0,000 0,02470106 0,06363034 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02470106 0,06356229 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02470106 0,06349438 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02470106 0,06342662 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02470106 0,063359 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02470106 0,06329152 ! response to UV-B GO:0010224 16 8 0,000 0,02470106 0,06322419 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02470106 0,063157 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02470106 0,06308996 ! intermediate filament organization GO:0045109 12 8 0,000 0,02470106 0,06302305 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02470106 0,06295629 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02470106 0,06288967 ! cellular extravasation GO:0045123 12 8 0,000 0,02470106 0,06282319 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02470106 0,06275685 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02470106 0,06269065 ! response to antibiotic GO:0046677 11 8 0,000 0,02470106 0,06262459 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02470106 0,06255867 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02470106 0,06249289 ! DNA topological change GO:0006265 12 8 0,000 0,02470106 0,06242725 ! response to tropane GO:0014073 15 8 0,000 0,02470106 0,06236174 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02470106 0,06229637 ! melanosome transport GO:0032402 13 8 0,000 0,02470106 0,06223114 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02470106 0,06216605 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02470106 0,06210109 ! mast cell activation GO:0045576 14 8 0,000 0,02470106 0,06203626 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02470106 0,06197158 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02470106 0,06190702 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02470106 0,0618426 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02470106 0,06177832 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02470106 0,06171416 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02470106 0,06165015 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02470106 0,06158626 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02470106 0,06152251 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02470106 0,06145888 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02470106 0,06139539 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02470106 0,06133203 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02470106 0,0612688 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02470106 0,06120571 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02470106 0,06114274 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02470106 0,0610799 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02470106 0,06101719 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02470106 0,06095461 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02470106 0,06089215 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02470106 0,06082983 ! hormone catabolic process GO:0042447 17 8 0,000 0,02470106 0,06076763 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02470106 0,06070556 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02470106 0,06064361 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02470106 0,06058179 ! ATP catabolic process GO:0006200 11 8 0,000 0,02470106 0,0605201 ! blastocyst growth GO:0001832 19 8 0,000 0,02470106 0,06045854 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02470106 0,06039709 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02470106 0,06033578 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02470106 0,06027458 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02470106 0,06021352 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02470106 0,06015257 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02470106 0,06009175 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02470106 0,06003105 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02470106 0,05997047 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02470106 0,05991002 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02470106 0,05984969 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02470106 0,05978948 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02470106 0,05972939 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02470106 0,05966942 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02470106 0,05960957 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02470106 0,05954984 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02470106 0,05949023 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02482312 0,05972442 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02541693 0,06109204 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02541693 0,06103107 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02662183 0,06386054 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,02662183 0,06379694 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02662183 0,06373346 ! response to drug GO:0042493 143 82 1,000 0,02723284 0,06513141 ! axon extension GO:0048675 15 9 0,000 0,02774593 0,06629266 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02774593 0,06622689 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02774593 0,06616126 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02774593 0,06609575 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02774593 0,06603037 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02774593 0,06596512 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02774593 0,06590001 ! phosphate transport GO:0006817 19 9 0,000 0,02774593 0,06583502 ! reproductive behavior GO:0019098 19 9 0,000 0,02774593 0,06577015 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02774593 0,06570542 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02774593 0,06564081 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02774593 0,06557633 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02774593 0,06551198 ! GTP metabolic process GO:0046039 9 9 0,000 0,02774593 0,06544775 ! RNA methylation GO:0001510 15 9 0,000 0,02774593 0,06538365 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02774593 0,06531967 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02774593 0,06525582 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02774593 0,0651921 ! artery development GO:0060840 24 9 0,000 0,02774593 0,06512849 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02774593 0,06506502 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02774593 0,06500166 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02774593 0,06493843 ! chemosensory behavior GO:0007635 20 9 0,000 0,02774593 0,06487532 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02774593 0,06481234 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02774593 0,06474947 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02774593 0,06468673 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02774593 0,06462411 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02774593 0,06456161 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02774593 0,06449923 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02774593 0,06443698 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02774593 0,06437484 ! protein targeting to ER GO:0045047 22 9 0,000 0,02774593 0,06431282 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02774593 0,06425092 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02774593 0,06418914 ! T cell selection GO:0045058 23 9 0,000 0,02774593 0,06412748 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02774593 0,06406594 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02774593 0,06400451 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02774593 0,06394321 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02774593 0,06388202 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02774593 0,06382094 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02774593 0,06375999 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02774593 0,06369915 ! mannose metabolic process GO:0006013 13 9 0,000 0,02774593 0,06363842 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02774593 0,06357782 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02774593 0,06351732 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02774593 0,06345695 ! receptor clustering GO:0043113 18 9 0,000 0,02774593 0,06339668 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02774593 0,06333653 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02774593 0,0632765 ! ruffle organization GO:0031529 15 9 0,000 0,02774593 0,06321658 ! retinol metabolic process GO:0042572 18 9 0,000 0,02774593 0,06315677 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02774593 0,06309708 ! behavioral fear response GO:0001662 22 9 0,000 0,02774593 0,06303749 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02774593 0,06297802 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02774593 0,06291867 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02774593 0,06285942 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02774593 0,06280029 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02774593 0,06274127 ! segment specification GO:0007379 13 9 0,000 0,02774593 0,06268235 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02774593 0,06262355 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02774593 0,06256486 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02774593 0,06250628 ! response to amine stimulus GO:0014075 13 9 0,000 0,02774593 0,06244781 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02774593 0,06238945 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02774593 0,06233119 ! erythrocyte development GO:0048821 15 9 0,000 0,02774593 0,06227305 ! gas homeostasis GO:0033483 16 9 0,000 0,02774593 0,06221501 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02774593 0,06215708 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02774593 0,06209926 ! renal water homeostasis GO:0003091 14 9 0,000 0,02774593 0,06204155 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02774593 0,06198394 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02774593 0,06192644 ! icosanoid secretion GO:0032309 15 9 0,000 0,02774593 0,06186905 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02774593 0,06181177 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02774593 0,06175459 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,02774593 0,06169751 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02774593 0,06164054 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02774593 0,06158368 ! sterol catabolic process GO:0016127 11 9 0,000 0,02774593 0,06152692 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02774593 0,06147026 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02774593 0,06141371 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02774593 0,06135727 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02774593 0,06130092 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02774593 0,06124468 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02774593 0,06118855 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02774593 0,06113252 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02774593 0,06107658 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02774593 0,06102076 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02774593 0,06096503 ! purine base metabolic process GO:0006144 21 9 0,000 0,02774593 0,0609094 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02774593 0,06085388 ! pigment granule transport GO:0051904 17 9 0,000 0,02774593 0,06079846 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02774593 0,06074314 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02774593 0,06068791 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02774593 0,06063279 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02774593 0,06057777 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02774593 0,06052285 ! mitochondrion localization GO:0051646 15 9 0,000 0,02774593 0,06046803 ! response to oxygen levels GO:0070482 176 83 1,000 0,02784949 0,0606388 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02909958 0,06330343 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 0,02973294 0,06462281 ! regulation of protein transport GO:0051223 154 87 1,000 0,03037178 0,06595172 GO:0070201|regulation of establishment of protein localization, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0307814 0,06678092 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0307814 0,06672076 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0307814 0,06666071 ! synapsis GO:0007129 13 10 0,000 0,0307814 0,06660076 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0307814 0,06654092 ! N-glycan processing GO:0006491 20 10 0,000 0,0307814 0,06648119 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0307814 0,06642156 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0307814 0,06636205 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0307814 0,06630264 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0307814 0,06624333 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0307814 0,06618413 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0307814 0,06612504 ! androgen metabolic process GO:0008209 17 10 0,000 0,0307814 0,06606605 ! phospholipid efflux GO:0033700 16 10 0,000 0,0307814 0,06600717 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0307814 0,06594839 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0307814 0,06588972 ! lung alveolus development GO:0048286 26 10 0,000 0,0307814 0,06583115 ! pathogenesis GO:0009405 13 10 0,000 0,0307814 0,06577269 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0307814 0,06571432 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0307814 0,06565607 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0307814 0,06559791 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0307814 0,06553986 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0307814 0,06548191 ! endoderm development GO:0007492 16 10 0,000 0,0307814 0,06542407 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0307814 0,06536632 ! arginine catabolic process GO:0006527 13 10 0,000 0,0307814 0,06530868 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0307814 0,06525114 ! proline metabolic process GO:0006560 13 10 0,000 0,0307814 0,0651937 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0307814 0,06513636 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0307814 0,06507912 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0307814 0,06502199 ! V(D)J recombination GO:0033151 28 10 0,000 0,0307814 0,06496495 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0307814 0,06490801 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0307814 0,06485118 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0307814 0,06479444 ! B cell proliferation GO:0042100 18 10 0,000 0,0307814 0,0647378 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0307814 0,06468126 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0307814 0,06462482 ! multicellular organism growth GO:0035264 18 10 0,000 0,0307814 0,06456848 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0307814 0,06451223 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0307814 0,06445609 ! epithelial cell development GO:0002064 20 10 0,000 0,0307814 0,06440004 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0307814 0,06434409 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0307814 0,06428823 ! macroautophagy GO:0016236 17 10 0,000 0,0307814 0,06423247 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0307814 0,06417681 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0307814 0,06412125 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0307814 0,06406578 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0307814 0,06401041 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0307814 0,06395513 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0307814 0,06389995 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0307814 0,06384487 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0307814 0,06378987 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0307814 0,06373498 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0307814 0,06368017 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0307814 0,06362547 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0307814 0,06357085 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0307814 0,06351633 ! response to dsRNA GO:0043331 20 10 0,000 0,0307814 0,06346191 ! DNA ligation GO:0006266 19 10 0,000 0,0307814 0,06340757 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0307814 0,06335333 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0307814 0,06329918 ! melanosome localization GO:0032400 16 10 0,000 0,0307814 0,06324513 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0307814 0,06319116 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0307814 0,06313729 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0307814 0,06308351 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0307814 0,06302982 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0307814 0,06297623 ! mRNA cleavage GO:0006379 17 10 0,000 0,0307814 0,06292272 ! protein sumoylation GO:0016925 15 10 0,000 0,0307814 0,06286931 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0307814 0,06281598 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0307814 0,06276275 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0307814 0,0627096 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0307814 0,06265655 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0307814 0,06260359 ! salivary gland development GO:0007431 27 10 0,000 0,0307814 0,06255071 ! prophase GO:0051324 15 10 0,000 0,0307814 0,06249793 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0307814 0,06244523 ! apical protein localization GO:0045176 15 10 0,000 0,0307814 0,06239262 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0307814 0,0623401 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0307814 0,06228767 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0307814 0,06223533 ! midbrain development GO:0030901 13 10 0,000 0,0307814 0,06218308 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0307814 0,06213091 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0307814 0,06207883 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0307814 0,06202684 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0307814 0,06197493 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0307814 0,06192311 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0307814 0,06187138 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0307814 0,06181974 ! detection of calcium ion GO:0005513 23 10 0,000 0,0307814 0,06176818 ! oocyte development GO:0048599 17 10 0,000 0,0307814 0,0617167 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0307814 0,06166532 ! blastocyst formation GO:0001825 17 10 0,000 0,0307814 0,06161401 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0307814 0,0615628 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0307814 0,06151166 ! activation of innate immune response GO:0002218 12 10 0,000 0,0307814 0,06146062 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0307814 0,06140965 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0307814 0,06135878 ! response to nicotine GO:0035094 20 10 0,000 0,0307814 0,06130798 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0307814 0,06125727 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0307814 0,06120665 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0307814 0,06115611 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,03101608 0,06157152 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03101608 0,06152076 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03166578 0,06275771 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,03166578 0,06270606 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03232085 0,06395063 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03380749 0,06683716 ! respiratory burst GO:0045730 17 11 0,000 0,03380749 0,06678228 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03380749 0,0667275 ! neuron fate specification GO:0048665 17 11 0,000 0,03380749 0,0666728 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03380749 0,0666182 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03380749 0,06656368 ! thyroid gland development GO:0030878 26 11 0,000 0,03380749 0,06650926 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03380749 0,06645492 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03380749 0,06640067 ! response to pain GO:0048265 24 11 0,000 0,03380749 0,06634651 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03380749 0,06629244 ! T cell proliferation GO:0042098 26 11 0,000 0,03380749 0,06623845 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03380749 0,06618456 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03380749 0,06613075 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03380749 0,06607703 ! bone resorption GO:0045453 16 11 0,000 0,03380749 0,06602339 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03380749 0,06596985 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03380749 0,06591639 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03380749 0,06586301 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03380749 0,06580973 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03380749 0,06575652 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03380749 0,06570341 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03380749 0,06565038 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03380749 0,06559744 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03380749 0,06554458 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03380749 0,0654918 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03380749 0,06543912 ! UV protection GO:0009650 19 11 0,000 0,03380749 0,06538651 ! adult heart development GO:0007512 14 11 0,000 0,03380749 0,06533399 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03380749 0,06528156 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03380749 0,06522921 ! temperature homeostasis GO:0001659 17 11 0,000 0,03380749 0,06517694 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03380749 0,06512476 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03380749 0,06507266 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03380749 0,06502064 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03380749 0,06496871 ! regulation of organ growth GO:0046620 13 11 0,000 0,03380749 0,06491686 ! pigment granule localization GO:0051875 20 11 0,000 0,03380749 0,06486509 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03380749 0,0648134 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03380749 0,0647618 ! embryonic axis specification GO:0000578 18 11 0,000 0,03380749 0,06471028 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03380749 0,06465884 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03380749 0,06460748 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03380749 0,06455621 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03380749 0,06450501 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03380749 0,0644539 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03380749 0,06440287 ! zymogen activation GO:0031638 15 11 0,000 0,03380749 0,06435191 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03380749 0,06430104 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03380749 0,06425025 ! nucleosome positioning GO:0016584 15 11 0,000 0,03380749 0,06419954 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03380749 0,06414891 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03380749 0,06409836 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03380749 0,06404789 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03380749 0,0639975 ! acid secretion GO:0046717 18 11 0,000 0,03380749 0,06394719 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03380749 0,06389695 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03380749 0,0638468 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03380749 0,06379672 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03380749 0,06374672 ! oocyte differentiation GO:0009994 18 11 0,000 0,03380749 0,06369681 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03380749 0,06364696 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03380749 0,0635972 ! cholesterol efflux GO:0033344 19 11 0,000 0,03380749 0,06354752 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03380749 0,06349791 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03380749 0,06344838 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03380749 0,06339892 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03380749 0,06334955 ! embryonic gut development GO:0048566 15 11 0,000 0,03380749 0,06330025 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03380749 0,06325103 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03380749 0,06320188 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03380749 0,06315281 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03380749 0,06310382 ! defense response to fungus GO:0050832 13 11 0,000 0,03380749 0,0630549 ! developmental induction GO:0031128 19 11 0,000 0,03380749 0,06300606 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03380749 0,06295729 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03380749 0,0629086 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03380749 0,06285998 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03380749 0,06281144 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03380749 0,06276298 ! nucleus localization GO:0051647 19 11 0,000 0,03380749 0,06271459 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03380749 0,06266627 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03499406 0,06481579 ! forebrain development GO:0030900 188 95 1,000 0,0356754 0,06602694 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03636188 0,06724572 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03682423 0,06804847 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03682423 0,06799624 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03682423 0,0679441 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03682423 0,06789204 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03682423 0,06784005 ! cartilage condensation GO:0001502 20 12 0,000 0,03682423 0,06778815 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03682423 0,06773632 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03682423 0,06768457 ! protein complex disassembly GO:0043241 27 12 0,000 0,03682423 0,06763291 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03682423 0,06758132 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03682423 0,06752981 ! hippocampus development GO:0021766 26 12 0,000 0,03682423 0,06747838 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03682423 0,06742702 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03682423 0,06737575 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03682423 0,06732455 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03682423 0,06727343 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03682423 0,06722239 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03682423 0,06717142 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03682423 0,06712054 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03682423 0,06706972 ! drug transport GO:0015893 16 12 0,000 0,03682423 0,06701899 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03682423 0,06696833 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03682423 0,06691775 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03682423 0,06686725 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03682423 0,06681682 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03682423 0,06676647 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03682423 0,06671619 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03682423 0,06666599 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03682423 0,06661587 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03682423 0,06656582 ! entry into host cell GO:0030260 32 12 0,000 0,03682423 0,06651585 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03682423 0,06646595 ! monoamine transport GO:0015844 18 12 0,000 0,03682423 0,06641612 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03682423 0,06636637 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03682423 0,0663167 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03682423 0,0662671 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03682423 0,06621757 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03682423 0,06616812 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03682423 0,06611874 ! protein homotetramerization GO:0051289 21 12 0,000 0,03682423 0,06606943 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03682423 0,0660202 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03682423 0,06597104 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03682423 0,06592195 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03682423 0,06587294 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03682423 0,065824 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03682423 0,06577513 ! cranial nerve development GO:0021545 20 12 0,000 0,03682423 0,06572634 ! fucose catabolic process GO:0019317 22 12 0,000 0,03682423 0,06567762 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03682423 0,06562897 ! histone methylation GO:0016571 26 12 0,000 0,03682423 0,06558039 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03682423 0,06553188 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03682423 0,06548345 ! gland morphogenesis GO:0022612 29 12 0,000 0,03682423 0,06543509 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03682423 0,06538679 ! T cell homeostasis GO:0043029 25 12 0,000 0,03682423 0,06533857 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03682423 0,06529042 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03682423 0,06524235 ! spleen development GO:0048536 22 12 0,000 0,03682423 0,06519434 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03682423 0,0651464 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03682423 0,06509854 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03682423 0,06505074 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03682423 0,06500301 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03682423 0,06495536 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03682423 0,06490777 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03682423 0,06486025 ! response to cold GO:0009409 17 12 0,000 0,03682423 0,06481281 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03682423 0,06476543 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03682423 0,06471812 ! regulation of protein localization GO:0032880 176 97 1,000 0,03705346 0,06507344 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03983166 0,06990151 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03983166 0,06985056 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03983166 0,06979969 ! peroxisomal transport GO:0043574 24 13 0,000 0,03983166 0,06974889 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03983166 0,06969816 ! lipid localization GO:0010876 28 13 0,000 0,03983166 0,06964751 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03983166 0,06959693 ! organelle fusion GO:0048284 32 13 0,000 0,03983166 0,06954642 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03983166 0,06949599 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03983166 0,06944563 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03983166 0,06939534 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03983166 0,06934513 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03983166 0,06929499 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03983166 0,06924492 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03983166 0,06919492 ! methionine metabolic process GO:0006555 27 13 0,000 0,03983166 0,069145 ! plasma membrane organization GO:0007009 24 13 0,000 0,03983166 0,06909515 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03983166 0,06904537 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03983166 0,06899566 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03983166 0,06894602 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03983166 0,06889646 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03983166 0,06884696 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03983166 0,06879754 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03983166 0,06874819 ! exocrine system development GO:0035272 32 13 0,000 0,03983166 0,0686989 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03983166 0,06864969 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03983166 0,06860055 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03983166 0,06855148 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03983166 0,06850248 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03983166 0,06845355 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03983166 0,06840469 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03983166 0,0683559 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03983166 0,06830718 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03983166 0,06825853 ! ribosome assembly GO:0042255 17 13 0,000 0,03983166 0,06820994 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03983166 0,06816143 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03983166 0,06811299 ! chromatin silencing GO:0006342 26 13 0,000 0,03983166 0,06806461 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03983166 0,0680163 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03983166 0,06796806 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03983166 0,06791989 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03983166 0,06787179 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03983166 0,06782376 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03983166 0,06777579 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03983166 0,06772789 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03983166 0,06768006 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03983166 0,0676323 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03983166 0,06758461 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03983166 0,06753698 ! embryonic placenta development GO:0001892 23 13 0,000 0,03983166 0,06748942 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03983166 0,06744192 ! insulin secretion GO:0030073 23 13 0,000 0,03983166 0,06739449 ! actin filament polymerization GO:0030041 24 13 0,000 0,03983166 0,06734713 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03983166 0,06729984 ! acrosome reaction GO:0007340 18 13 0,000 0,03983166 0,06725261 ! rRNA transcription GO:0009303 25 14 0,000 0,04282979 0,07226401 ! lactation GO:0007595 26 14 0,000 0,04282979 0,07221337 ! reproductive cellular process GO:0048610 20 14 0,000 0,04282979 0,0721628 ! tRNA modification GO:0006400 20 14 0,000 0,04282979 0,0721123 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04282979 0,07206187 ! regulation of S phase GO:0033261 23 14 0,000 0,04282979 0,07201152 ! water transport GO:0006833 21 14 0,000 0,04282979 0,07196123 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04282979 0,07191101 ! non-recombinational repair GO:0000726 25 14 0,000 0,04282979 0,07186087 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04282979 0,07181079 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04282979 0,07176078 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04282979 0,07171084 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04282979 0,07166097 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04282979 0,07161118 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04282979 0,07156145 ! palate development GO:0060021 31 14 0,000 0,04282979 0,07151178 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04282979 0,07146219 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04282979 0,07141267 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04282979 0,07136321 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04282979 0,07131383 ! arginine metabolic process GO:0006525 17 14 0,000 0,04282979 0,07126451 ! regulation of heart rate GO:0002027 24 14 0,000 0,04282979 0,07121526 ! organic alcohol transport GO:0015850 29 14 0,000 0,04282979 0,07116608 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04282979 0,07111696 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04282979 0,07106792 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04282979 0,07101894 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04282979 0,07097003 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04282979 0,07092118 ! L-amino acid transport GO:0015807 30 14 0,000 0,04282979 0,07087241 ! bone mineralization GO:0030282 17 14 0,000 0,04282979 0,0708237 ! stem cell development GO:0048864 43 14 0,000 0,04282979 0,07077506 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04282979 0,07072648 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04282979 0,07067797 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04282979 0,07062953 ! cerebellum development GO:0021549 21 14 0,000 0,04282979 0,07058115 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04282979 0,07053284 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04282979 0,0704846 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04282979 0,07043642 ! cofactor transport GO:0051181 26 14 0,000 0,04282979 0,07038831 ! NADP metabolic process GO:0006739 24 14 0,000 0,04282979 0,07034026 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04282979 0,07029228 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04282979 0,07024436 ! intestinal absorption GO:0050892 25 14 0,000 0,04282979 0,07019651 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04282979 0,07014873 ! oxygen transport GO:0015671 21 14 0,000 0,04282979 0,07010101 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04282979 0,07005335 ! male genitalia development GO:0030539 24 14 0,000 0,04282979 0,07000576 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04282979 0,06995824 ! regulation of axon extension GO:0030516 37 14 0,000 0,04282979 0,06991077 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04282979 0,06986338 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04581866 0,07468815 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04581866 0,07463758 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04581866 0,07458708 ! superoxide anion generation GO:0042554 20 15 0,000 0,04581866 0,07453665 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04581866 0,07448629 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04581866 0,07443599 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04581866 0,07438577 ! copper ion transport GO:0006825 20 15 0,000 0,04581866 0,07433561 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04581866 0,07428552 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04581866 0,07423549 ! sulfate transport GO:0008272 23 15 0,000 0,04581866 0,07418554 ! response to cAMP GO:0051591 22 15 0,000 0,04581866 0,07413565 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04581866 0,07408582 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04581866 0,07403607 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04581866 0,07398638 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04581866 0,07393676 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04581866 0,0738872 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04581866 0,07383771 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04581866 0,07378829 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04581866 0,07373893 ! vesicle coating GO:0006901 33 15 0,000 0,04581866 0,07368964 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04581866 0,07364042 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04581866 0,07359126 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04581866 0,07354217 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04581866 0,07349314 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04581866 0,07344417 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04581866 0,07339528 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04581866 0,07334644 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04581866 0,07329768 ! histone deacetylation GO:0016575 20 15 0,000 0,04581866 0,07324897 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04581866 0,07320034 ! tissue regeneration GO:0042246 26 15 0,000 0,04581866 0,07315176 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04581866 0,07310325 ! water homeostasis GO:0030104 27 15 0,000 0,04581866 0,07305481 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04581866 0,07300643 ! muscle maintenance GO:0046716 26 15 0,000 0,04581866 0,07295811 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04581866 0,07290986 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04581866 0,07286167 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04581866 0,07281354 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04581866 0,07276548 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04581866 0,07271748 ! cell killing GO:0001906 29 15 0,000 0,04581866 0,07266955 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04581866 0,07262168 ! detection of bacterium GO:0016045 18 15 0,000 0,04581866 0,07257387 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04581866 0,07252612 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04581866 0,07247844 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04581866 0,07243082 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04581866 0,07238326 ! peptide hormone processing GO:0016486 23 15 0,000 0,04581866 0,07233576 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0487983 0,07698932 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0487983 0,07693887 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0487983 0,07688848 ! bone remodeling GO:0046849 27 16 0,000 0,0487983 0,07683816 ! filopodium assembly GO:0046847 32 16 0,000 0,0487983 0,07678791 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0487983 0,07673772 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0487983 0,0766876 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0487983 0,07663754 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0487983 0,07658755 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0487983 0,07653762 ! startle response GO:0001964 28 16 0,000 0,0487983 0,07648776 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0487983 0,07643796 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0487983 0,07638823 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0487983 0,07633857 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0487983 0,07628896 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0487983 0,07623942 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0487983 0,07618995 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0487983 0,07614054 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0487983 0,07609119 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0487983 0,07604191 ! response to osmotic stress GO:0006970 25 16 0,000 0,0487983 0,07599269 ! lysosomal transport GO:0007041 26 16 0,000 0,0487983 0,07594354 ! fructose metabolic process GO:0006000 25 16 0,000 0,0487983 0,07589445 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0487983 0,07584542 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0487983 0,07579646 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0487983 0,07574756 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0487983 0,07569872 ! axon cargo transport GO:0008088 43 16 0,000 0,0487983 0,07564994 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0487983 0,07560123 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0487983 0,07555258 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0487983 0,075504 ! DNA replication initiation GO:0006270 27 16 0,000 0,0487983 0,07545547 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0487983 0,07540701 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0487983 0,07535861 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0487983 0,07531027 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0487983 0,075262 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0487983 0,07521378 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0487983 0,07516563 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0487983 0,07511754 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0487983 0,07506951 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0487983 0,07502154 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0487983 0,07497364 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0487983 0,07492579 ! defense response to virus GO:0051607 37 16 0,000 0,0487983 0,07487801 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05176873 0,07938532 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05176873 0,07933476 ! metencephalon development GO:0022037 30 17 0,000 0,05176873 0,07928426 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05176873 0,07923382 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05176873 0,07918345 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05176873 0,07913315 ! signal complex assembly GO:0007172 41 17 0,000 0,05176873 0,0790829 ! endothelial cell migration GO:0043542 28 17 0,000 0,05176873 0,07903272 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05176873 0,07898261 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05176873 0,07893255 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05176873 0,07888257 ! adult walking behavior GO:0007628 33 17 0,000 0,05176873 0,07883264 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05176873 0,07878278 ! heart looping GO:0001947 30 17 0,000 0,05176873 0,07873298 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05176873 0,07868324 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05176873 0,07863357 ! myoblast differentiation GO:0045445 45 17 0,000 0,05176873 0,07858396 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05176873 0,07853441 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05176873 0,07848492 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05176873 0,0784355 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05176873 0,07838614 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05176873 0,07833684 ! glycine metabolic process GO:0006544 28 17 0,000 0,05176873 0,0782876 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05176873 0,07823842 ! NAD metabolic process GO:0019674 29 17 0,000 0,05176873 0,07818931 ! membrane budding GO:0006900 37 17 0,000 0,05176873 0,07814026 ! DNA integration GO:0015074 29 17 0,000 0,05176873 0,07809127 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05176873 0,07804234 ! regulation of protein binding GO:0043393 33 17 0,000 0,05176873 0,07799347 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05176873 0,07794466 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05176873 0,07789592 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05176873 0,07784723 ! genitalia development GO:0048806 30 17 0,000 0,05176873 0,07779861 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05176873 0,07775004 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05176873 0,07770154 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05176873 0,0776531 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05176873 0,07760472 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05176873 0,0775564 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05176873 0,07750813 ! steroid catabolic process GO:0006706 31 17 0,000 0,05176873 0,07745993 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05176873 0,07741179 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05176873 0,07736371 ! gas transport GO:0015669 25 17 0,000 0,05176873 0,07731569 ! organic cation transport GO:0015695 31 17 0,000 0,05176873 0,07726772 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05176873 0,07721982 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05176873 0,07717198 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05176873 0,07712419 ! microspike assembly GO:0030035 36 17 0,000 0,05176873 0,07707647 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05176873 0,0770288 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05472999 0,08138464 ! neuron maturation GO:0042551 42 18 0,000 0,05472999 0,08133437 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05472999 0,08128417 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,05472999 0,08123402 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05472999 0,08118394 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05472999 0,08113392 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05472999 0,08108396 ! memory GO:0007613 31 18 0,000 0,05472999 0,08103406 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05472999 0,08098422 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05472999 0,08093445 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05472999 0,08088473 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05472999 0,08083508 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05472999 0,08078549 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05472999 0,08073596 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05472999 0,08068649 ! response to retinoic acid GO:0032526 26 18 0,000 0,05472999 0,08063708 ! response to fungus GO:0009620 21 18 0,000 0,05472999 0,08058773 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05472999 0,08053844 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05472999 0,08048921 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05472999 0,08044004 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05472999 0,08039093 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05472999 0,08034188 ! vitamin transport GO:0051180 27 18 0,000 0,05472999 0,0802929 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05472999 0,08024397 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05472999 0,0801951 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05472999 0,08014629 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05472999 0,08009754 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05472999 0,08004884 ! nerve development GO:0021675 28 18 0,000 0,05472999 0,08000021 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05472999 0,07995164 ! protein secretion GO:0009306 39 19 0,000 0,05768209 0,08421305 ! positive regulation of translation GO:0045727 30 19 0,000 0,05768209 0,08416198 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05768209 0,08411098 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05768209 0,08406003 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05768209 0,08400915 ! skin development GO:0043588 36 19 0,000 0,05768209 0,08395832 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05768209 0,08390756 ! lipid phosphorylation GO:0046834 35 19 0,000 0,05768209 0,08385686 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05768209 0,08380623 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05768209 0,08375565 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05768209 0,08370513 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05768209 0,08365468 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05768209 0,08360428 ! pigmentation during development GO:0048066 41 19 0,000 0,05768209 0,08355395 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05768209 0,08350368 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05768209 0,08345346 ! heme metabolic process GO:0042168 36 19 0,000 0,05768209 0,08340331 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05768209 0,08335322 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05768209 0,08330319 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05768209 0,08325322 ! peptide cross-linking GO:0018149 37 19 0,000 0,05768209 0,0832033 ! protein export from nucleus GO:0006611 36 19 0,000 0,05768209 0,08315345 ! heart process GO:0003015 30 19 0,000 0,05768209 0,08310366 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05768209 0,08305393 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05768209 0,08300425 ! visual learning GO:0008542 36 19 0,000 0,05768209 0,08295464 ! cellular pigmentation GO:0033059 36 19 0,000 0,05768209 0,08290508 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05768209 0,08285559 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05768209 0,08280615 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05768209 0,08275677 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05768209 0,08270746 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05768209 0,0826582 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05768209 0,08260899 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05768209 0,08255985 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05768209 0,08251077 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05768209 0,08246174 ! cilium assembly GO:0042384 37 19 0,000 0,05768209 0,08241277 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05768209 0,08236386 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06062507 0,08651478 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06062507 0,0864635 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06062507 0,08641228 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06062507 0,08636112 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06062507 0,08631002 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06062507 0,08625897 ! response to vitamin GO:0033273 31 20 0,000 0,06062507 0,08620799 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06062507 0,08615707 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06062507 0,08610621 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06062507 0,08605541 ! response to alkaloid GO:0043279 38 20 0,000 0,06062507 0,08600467 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06062507 0,08595399 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06062507 0,08590337 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06062507 0,08585281 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06062507 0,08580231 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06062507 0,08575187 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06062507 0,08570148 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06062507 0,08565116 ! body fluid secretion GO:0007589 31 20 0,000 0,06062507 0,0856009 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06062507 0,08555069 ! peptide secretion GO:0002790 35 20 0,000 0,06062507 0,08550054 ! stem cell differentiation GO:0048863 53 20 0,000 0,06062507 0,08545045 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06062507 0,08540043 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06062507 0,08535045 ! sensory perception of pain GO:0019233 30 20 0,000 0,06062507 0,08530054 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06062507 0,08525069 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06062507 0,08520089 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06062507 0,08515115 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06062507 0,08510147 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06062507 0,08505185 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06062507 0,08500229 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06062507 0,08495278 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06062507 0,08490333 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06062507 0,08485394 ! regulation of glucose import GO:0046324 29 20 0,000 0,06062507 0,08480461 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06062507 0,08475533 ! actin filament-based movement GO:0030048 43 20 0,000 0,06062507 0,08470611 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06062507 0,08465695 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06062507 0,08460785 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06062507 0,0845588 ! regulation of cell killing GO:0031341 42 21 0,000 0,06355896 0,08859957 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06355896 0,08854827 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06355896 0,08849703 ! hormone secretion GO:0046879 38 21 0,000 0,06355896 0,08844584 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06355896 0,08839472 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06355896 0,08834365 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06355896 0,08829265 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06355896 0,0882417 ! axis specification GO:0009798 38 21 0,000 0,06355896 0,08819081 ! ovarian follicle development GO:0001541 35 21 0,000 0,06355896 0,08813998 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06355896 0,08808921 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06355896 0,08803849 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06355896 0,08798784 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06355896 0,08793724 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06355896 0,0878867 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06355896 0,08783622 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06355896 0,0877858 ! cytolysis GO:0019835 24 21 0,000 0,06355896 0,08773543 ! vasodilation GO:0042311 39 21 0,000 0,06355896 0,08768513 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06355896 0,08763488 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06355896 0,08758469 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06355896 0,08753455 ! oogenesis GO:0048477 36 21 0,000 0,06355896 0,08748447 ! DNA modification GO:0006304 34 21 0,000 0,06355896 0,08743446 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06355896 0,08738449 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06355896 0,08733459 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06355896 0,08728474 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06355896 0,08723495 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06355896 0,08718521 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06355896 0,08713553 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06355896 0,08708591 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06355896 0,08703635 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06355896 0,08698684 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06355896 0,08693739 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06355896 0,08688799 ! collagen catabolic process GO:0030574 28 21 0,000 0,06355896 0,08683865 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06355896 0,08678937 ! gut development GO:0048565 39 21 0,000 0,06355896 0,08674014 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06648378 0,09068026 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06648378 0,09062889 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06648378 0,09057757 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06648378 0,09052631 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06648378 0,0904751 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06648378 0,09042396 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06648378 0,09037287 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06648378 0,09032184 ! regeneration GO:0031099 41 22 0,000 0,06648378 0,09027087 ! keratinization GO:0031424 28 22 0,000 0,06648378 0,09021996 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06648378 0,0901691 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06648378 0,0901183 ! sensory perception of taste GO:0050909 28 22 0,000 0,06648378 0,09006756 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06648378 0,09001687 ! vacuolar transport GO:0007034 36 22 0,000 0,06648378 0,08996625 ! lysosome organization GO:0007040 41 22 0,000 0,06648378 0,08991567 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06648378 0,08986516 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06648378 0,0898147 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06648378 0,0897643 ! fucose metabolic process GO:0006004 39 22 0,000 0,06648378 0,08971396 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06648378 0,08966367 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06648378 0,08961344 ! ureteric bud development GO:0001657 43 22 0,000 0,06648378 0,08956326 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06648378 0,08951314 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06648378 0,08946308 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06648378 0,08941307 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06648378 0,08936312 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06648378 0,08931322 ! sarcomere organization GO:0045214 30 22 0,000 0,06648378 0,08926338 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06648378 0,0892136 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06648378 0,08916387 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06648378 0,0891142 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06648378 0,08906458 ! protein stabilization GO:0050821 39 22 0,000 0,06648378 0,08901502 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06939957 0,09286728 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06939957 0,09281565 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06939957 0,09276409 ! gluconeogenesis GO:0006094 33 23 0,000 0,06939957 0,09271258 ! viral genome replication GO:0019079 41 23 0,000 0,06939957 0,09266113 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06939957 0,09260974 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06939957 0,0925584 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06939957 0,09250713 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06939957 0,0924559 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06939957 0,09240474 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06939957 0,09235363 ! visual behavior GO:0007632 42 23 0,000 0,06939957 0,09230258 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06939957 0,09225158 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06939957 0,09220064 ! response to ethanol GO:0045471 46 23 0,000 0,06939957 0,09214976 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06939957 0,09209893 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06939957 0,09204816 ! peroxisome organization GO:0007031 37 23 0,000 0,06939957 0,09199744 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06939957 0,09194679 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06939957 0,09189618 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06939957 0,09184563 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06939957 0,09179514 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06939957 0,0917447 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06939957 0,09169432 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06939957 0,091644 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06939957 0,09159373 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06939957 0,09154351 ! fatty acid transport GO:0015908 44 23 0,000 0,06939957 0,09149335 ! platelet activation GO:0030168 37 23 0,000 0,06939957 0,09144324 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06939957 0,09139319 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06939957 0,0913432 ! hormone transport GO:0009914 40 23 0,000 0,06939957 0,09129325 ! cell-cell recognition GO:0009988 25 23 0,000 0,06939957 0,09124337 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06939957 0,09119353 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06939957 0,09114376 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06939957 0,09109403 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06939957 0,09104436 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06939957 0,09099475 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07230634 0,09475439 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07230634 0,09470281 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07230634 0,09465128 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07230634 0,09459981 ! vesicle docking GO:0048278 47 24 0,000 0,07230634 0,0945484 ! spinal cord development GO:0021510 47 24 0,000 0,07230634 0,09449704 ! vacuole organization GO:0007033 43 24 0,000 0,07230634 0,09444574 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07230634 0,0943945 ! digestive system process GO:0022600 39 24 0,000 0,07230634 0,09434331 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07230634 0,09429217 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07230634 0,09424109 ! regulation of behavior GO:0050795 43 24 0,000 0,07230634 0,09419007 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07230634 0,0941391 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07230634 0,09408819 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07230634 0,09403733 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07230634 0,09398653 ! membrane depolarization GO:0051899 39 24 0,000 0,07230634 0,09393578 ! pentose metabolic process GO:0019321 35 24 0,000 0,07230634 0,09388508 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07230634 0,09383444 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07230634 0,09378386 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07230634 0,09373333 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07230634 0,09368285 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07230634 0,09363243 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07230634 0,09358206 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07230634 0,09353175 ! regulation of amine transport GO:0051952 40 24 0,000 0,07230634 0,09348149 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07520413 0,09717569 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07520413 0,09712353 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07520413 0,09707143 ! phototransduction GO:0007602 33 25 0,000 0,07520413 0,09701938 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07520413 0,09696739 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07520413 0,09691545 ! sperm motility GO:0030317 31 25 0,000 0,07520413 0,09686357 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07520413 0,09681174 ! receptor metabolic process GO:0043112 46 25 0,000 0,07520413 0,09675997 ! chromosome condensation GO:0030261 45 25 0,000 0,07520413 0,09670825 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07520413 0,09665659 ! neural crest cell development GO:0014032 54 25 0,000 0,07520413 0,09660499 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07520413 0,09655344 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07520413 0,09650194 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07520413 0,0964505 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07520413 0,09639912 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07520413 0,09634779 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07520413 0,09629651 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07520413 0,09624529 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07520413 0,09619412 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07520413 0,09614301 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07520413 0,09609195 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07520413 0,09604095 ! telomere organization GO:0032200 43 25 0,000 0,07520413 0,09599 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07520413 0,0959391 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07520413 0,09588826 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07809297 0,0995189 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07809297 0,09946621 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07809297 0,09941359 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07809297 0,09936101 ! initiation of viral infection GO:0019059 57 26 0,000 0,07809297 0,0993085 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07809297 0,09925604 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07809297 0,09920363 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07809297 0,09915128 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07809297 0,09909899 ! molting cycle process GO:0022404 50 26 0,000 0,07809297 0,09904675 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07809297 0,09899456 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07809297 0,09894243 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07809297 0,09889036 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07809297 0,09883834 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07809297 0,09878637 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07809297 0,09873446 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07809297 0,0986826 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07809297 0,0986308 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07809297 0,09857905 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07809297 0,09852736 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07809297 0,09847572 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07809297 0,09842414 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07809297 0,09837261 ! blastocyst development GO:0001824 49 26 0,000 0,07809297 0,09832113 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07809297 0,09826971 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07809297 0,09821834 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07809297 0,09816702 ! neuron fate commitment GO:0048663 48 27 0,000 0,08097287 0,10173406 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08097287 0,10168097 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,08097287 0,10162793 ! iron ion transport GO:0006826 59 27 0,000 0,08097287 0,10157494 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08097287 0,10152201 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08097287 0,10146913 ! fat cell differentiation GO:0045444 50 27 0,000 0,08097287 0,10141631 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08097287 0,10136354 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08097287 0,10131083 ! autophagy GO:0006914 41 27 0,000 0,08097287 0,10125818 ! male gonad development GO:0008584 44 27 0,000 0,08097287 0,10120558 ! response to toxin GO:0009636 47 27 0,000 0,08097287 0,10115303 ! primary neural tube formation GO:0014020 51 27 0,000 0,08097287 0,10110054 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08097287 0,1010481 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08097287 0,10099571 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08097287 0,10094338 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08097287 0,10089111 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08097287 0,10083889 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08097287 0,10078672 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08097287 0,10073461 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08384388 0,10425239 ! circadian rhythm GO:0007623 50 28 0,000 0,08384388 0,10419854 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08384388 0,10414475 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08384388 0,10409101 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08384388 0,10403732 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08384388 0,1039837 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08384388 0,10393012 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08384388 0,10387661 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08384388 0,10382315 ! synaptogenesis GO:0007416 42 28 0,000 0,08384388 0,10376974 ! lipid oxidation GO:0034440 43 28 0,000 0,08384388 0,10371639 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08384388 0,10366309 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08384388 0,10360985 ! translational initiation GO:0006413 65 29 0,000 0,08670601 0,10709171 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08670601 0,10703677 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08670601 0,10698188 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08670601 0,10692704 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08670601 0,10687226 ! catechol metabolic process GO:0009712 54 29 0,000 0,08670601 0,10681754 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08670601 0,10676288 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08670601 0,10670827 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08670601 0,10665371 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08670601 0,10659921 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08670601 0,10654477 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08670601 0,10649038 ! cell fate determination GO:0001709 60 29 0,000 0,08670601 0,10643605 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08670601 0,10638177 ! detection of light stimulus GO:0009583 38 29 0,000 0,08670601 0,10632755 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08670601 0,10627339 ! tissue homeostasis GO:0001894 48 29 0,000 0,08670601 0,10621928 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08670601 0,10616522 ! phenol metabolic process GO:0018958 55 30 0,000 0,08955929 0,10960308 ! zinc ion transport GO:0006829 45 30 0,000 0,08955929 0,10954736 ! membrane docking GO:0022406 61 30 0,000 0,08955929 0,1094917 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08955929 0,10943609 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08955929 0,10938054 ! acute-phase response GO:0006953 49 30 0,000 0,08955929 0,10932504 ! myofibril assembly GO:0030239 47 30 0,000 0,08955929 0,10926961 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08955929 0,10921422 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08955929 0,1091589 ! phospholipid transport GO:0015914 51 30 0,000 0,08955929 0,10910363 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08955929 0,10904841 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08955929 0,10899325 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08955929 0,10893815 ! eye morphogenesis GO:0048592 60 30 0,000 0,08955929 0,1088831 ! response to heat GO:0009408 50 30 0,000 0,08955929 0,10882811 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09240376 0,11222789 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09240376 0,11217126 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09240376 0,1121147 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09240376 0,11205819 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09240376 0,11200174 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09240376 0,11194534 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09240376 0,111889 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09240376 0,11183272 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09240376 0,11177649 ! ovulation cycle process GO:0022602 49 31 0,000 0,09240376 0,11172033 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09240376 0,11166421 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09240376 0,11160816 ! peptide transport GO:0015833 55 31 0,000 0,09240376 0,11155216 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09240376 0,11149621 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09240376 0,11144032 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09240376 0,11138449 ! mesoderm formation GO:0001707 69 31 0,000 0,09240376 0,11132872 ! natural killer cell activation GO:0030101 45 31 0,000 0,09240376 0,111273 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09240376 0,11121733 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09240376 0,11116172 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09240376 0,11110617 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09240376 0,11105067 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09240376 0,11099523 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09523943 0,11434435 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09523943 0,11428732 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09523943 0,11423035 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09523943 0,11417343 ! cholesterol transport GO:0030301 56 32 0,000 0,09523943 0,11411657 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09523943 0,11405977 ! spliceosome assembly GO:0000245 67 32 0,000 0,09523943 0,11400302 ! spindle organization GO:0007051 46 32 0,000 0,09523943 0,11394633 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09523943 0,1138897 ! metanephros development GO:0001656 74 32 0,000 0,09523943 0,11383312 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09523943 0,1137766 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09523943 0,11372014 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,09523943 0,11366373 ! muscle cell development GO:0055001 49 32 0,000 0,09523943 0,11360737 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09523943 0,11355108 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09523943 0,11349484 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09523943 0,11343865 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09523943 0,11338252 ! ovulation cycle GO:0042698 51 32 0,000 0,09523943 0,11332645 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09523943 0,11327043 ! hindbrain development GO:0030902 61 32 0,000 0,09523943 0,11321446 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09523943 0,11315856 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09523943 0,1131027 ! gene silencing GO:0016458 65 32 0,000 0,09523943 0,1130469 ! post-embryonic development GO:0009791 69 33 0,000 0,09806634 0,11634498 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09806634 0,11628764 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09806634 0,11623035 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09806634 0,11617312 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09806634 0,11611595 ! cell fate specification GO:0001708 52 33 0,000 0,09806634 0,11605884 ! sterol transport GO:0015918 57 33 0,000 0,09806634 0,11600178 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09806634 0,11594477 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09806634 0,11588783 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09806634 0,11583093 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09806634 0,1157741 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09806634 0,11571732 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10088451 0,11898438 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10088451 0,11892608 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10088451 0,11886784 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10088451 0,11880966 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10088451 0,11875153 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10088451 0,11869346 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10088451 0,11863545 ! mismatch repair GO:0006298 46 34 0,000 0,10088451 0,11857749 ! spermatid development GO:0007286 63 34 0,000 0,10088451 0,11851959 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10088451 0,11846175 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10088451 0,11840396 ! placenta development GO:0001890 53 34 0,000 0,10088451 0,11834623 ! regulation of muscle development GO:0048634 70 35 0,000 0,10369396 0,12158269 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10369396 0,12152347 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10369396 0,1214643 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10369396 0,12140519 ! odontogenesis GO:0042476 66 35 0,000 0,10369396 0,12134615 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10369396 0,12128715 ! female gonad development GO:0008585 58 35 0,000 0,10369396 0,12122822 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10369396 0,12116934 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,10369396 0,12111052 ! neural tube formation GO:0001841 67 35 0,000 0,10369396 0,12105176 ! vesicle localization GO:0051648 64 35 0,000 0,10369396 0,12099305 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10649473 0,12420084 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10649473 0,12414066 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10649473 0,12408055 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10649473 0,12402049 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10649473 0,12396049 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,10649473 0,12390055 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10649473 0,12384066 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10649473 0,12378084 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10649473 0,12372107 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10649473 0,12366136 ! aerobic respiration GO:0009060 55 36 0,000 0,10649473 0,1236017 ! embryonic organ development GO:0048568 57 36 0,000 0,10649473 0,12354211 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10649473 0,12348257 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10928684 0,12665903 ! meiosis I GO:0007127 65 37 0,000 0,10928684 0,12659805 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10928684 0,12653713 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10928684 0,12647626 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10928684 0,12641546 ! organic anion transport GO:0015711 68 37 0,000 0,10928684 0,12635471 ! tissue remodeling GO:0048771 76 37 0,000 0,10928684 0,12629402 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,10928684 0,12623339 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10928684 0,12617282 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10928684 0,1261123 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10928684 0,12605184 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,10928684 0,12599145 ! pigment metabolic process GO:0042440 80 37 0,000 0,10928684 0,12593111 ! spermatid differentiation GO:0048515 66 37 0,000 0,10928684 0,12587082 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11207032 0,12901493 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11207032 0,12895323 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11207032 0,12889159 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11207032 0,12883 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11207032 0,12876848 ! lipid homeostasis GO:0055088 67 38 0,000 0,11207032 0,12870702 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11207032 0,12864561 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11207032 0,12858426 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11207032 0,12852297 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11207032 0,12846174 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1148452 0,13157978 ! ear morphogenesis GO:0042471 60 39 0,000 0,1148452 0,13151715 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1148452 0,13145459 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,1148452 0,13139208 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1148452 0,13132963 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1148452 0,13126724 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1148452 0,13120491 ! RNA modification GO:0009451 57 39 0,000 0,1148452 0,13114264 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1148452 0,13108043 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11761149 0,13417413 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11761149 0,13411054 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11761149 0,13404701 ! feeding behavior GO:0007631 59 40 0,000 0,11761149 0,13398354 ! negative regulation of binding GO:0051100 72 40 0,000 0,11761149 0,13392013 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11761149 0,13385678 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11761149 0,13379349 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11761149 0,13373027 ! maintenance of protein location GO:0045185 91 40 0,000 0,11761149 0,1336671 ! cytokinesis GO:0000910 72 40 0,000 0,11761149 0,13360399 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12036923 0,13667219 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12036923 0,13660772 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12036923 0,13654331 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12036923 0,13647896 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12036923 0,13641468 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12036923 0,13635045 ! female gamete generation GO:0007292 61 41 0,000 0,12036923 0,13628629 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12036923 0,13622218 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,12311844 0,13926797 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12311844 0,13920252 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12311844 0,13913714 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12311844 0,13907181 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12311844 0,13900655 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12311844 0,13894135 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,12311844 0,13887621 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12585915 0,14190118 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12585915 0,14183471 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12585915 0,14176831 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12585915 0,14170197 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12585915 0,14163569 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,12585915 0,14156948 ! neural tube development GO:0021915 77 43 0,000 0,12585915 0,14150332 ! striated muscle contraction GO:0006941 77 43 0,000 0,12585915 0,14143723 ! phagocytosis GO:0006909 90 43 0,000 0,12585915 0,1413712 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12585915 0,14130523 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12859138 0,14430544 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12859138 0,14423817 ! male sex differentiation GO:0046661 76 44 0,000 0,12859138 0,14417096 ! biopolymer methylation GO:0043414 84 44 0,000 0,12859138 0,14410381 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12859138 0,14403672 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12859138 0,14396969 ! developmental growth GO:0048589 82 44 0,000 0,12859138 0,14390273 ! maintenance of location in cell GO:0051651 97 44 0,000 0,12859138 0,14383583 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13131517 0,14681427 ! glycolysis GO:0006096 65 45 0,000 0,13131517 0,14674608 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13131517 0,14667795 ! leukocyte migration GO:0050900 68 45 0,000 0,13131517 0,14660988 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13131517 0,14654188 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13131517 0,14647395 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13131517 0,14640607 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13131517 0,14633826 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13131517 0,14627051 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13131517 0,14620282 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13131517 0,1461352 ! cell growth GO:0016049 84 45 0,000 0,13131517 0,14606764 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13403053 0,14901916 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13403053 0,14895033 ! pigmentation GO:0043473 100 46 0,000 0,13403053 0,14888156 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1367375 0,15181838 ! response to calcium ion GO:0051592 81 47 0,000 0,1367375 0,15174835 ! endosome transport GO:0016197 108 47 0,000 0,1367375 0,15167839 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1367375 0,15160849 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1367375 0,15153865 ! JNK cascade GO:0007254 91 47 0,000 0,1367375 0,15146889 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1367375 0,15139918 ! methylation GO:0032259 90 47 0,000 0,1367375 0,15132954 ! protein homooligomerization GO:0051260 76 47 0,000 0,1367375 0,15125996 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13943609 0,15417428 ! cellular component disassembly GO:0022411 86 48 0,000 0,13943609 0,15410346 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13943609 0,15403271 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13943609 0,15396202 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13943609 0,15389139 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13943609 0,15382083 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,13943609 0,15375034 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14212634 0,15664497 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,14212634 0,15657324 ! regulation of ion transport GO:0043269 77 49 0,000 0,14212634 0,15650159 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,14212634 0,15642999 ! peptide metabolic process GO:0006518 76 49 0,000 0,14212634 0,15635847 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14212634 0,156287 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14212634 0,15621561 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,14212634 0,15614428 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14212634 0,15607301 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14212634 0,15600181 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14212634 0,15593067 ! neuromuscular process GO:0050905 99 50 0,000 0,14480826 0,15880067 ! regulation of ossification GO:0030278 117 50 0,000 0,14480826 0,15872833 ! inner ear development GO:0048839 79 50 0,000 0,14480826 0,15865605 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14480826 0,15858383 ! viral infectious cycle GO:0019058 99 51 0,000 0,14748189 0,16143832 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14748189 0,16136491 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14748189 0,16129156 ! excretion GO:0007588 83 51 0,000 0,14748189 0,16121828 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14748189 0,16114506 ! chromatin remodeling GO:0006338 109 51 0,000 0,14748189 0,16107192 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,14748189 0,16099883 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14748189 0,16092582 ! vesicle organization GO:0016050 107 51 0,000 0,14748189 0,16085287 ! regulation of cell shape GO:0008360 125 51 0,000 0,14748189 0,16077999 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,14748189 0,16070717 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,15014725 0,16353748 ! membrane fusion GO:0006944 110 52 0,000 0,15014725 0,16346348 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,15014725 0,16338955 ! amino acid activation GO:0043038 92 52 0,000 0,15014725 0,16331568 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,15014725 0,16324188 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,15280437 0,16605569 ! RNA catabolic process GO:0006401 93 53 0,000 0,15280437 0,16598072 ! regulation of translational initiation GO:0006446 82 53 0,000 0,15280437 0,16590582 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,15280437 0,16583099 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,15280437 0,16575622 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,15280437 0,16568152 ! cell maturation GO:0048469 100 53 0,000 0,15280437 0,16560689 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,15280437 0,16553233 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15545326 0,16832608 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15545326 0,16825036 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15545326 0,16817471 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15545326 0,16809912 ! chloride transport GO:0006821 90 55 0,000 0,15809396 0,17087784 ! glucose catabolic process GO:0006007 82 55 0,000 0,15809396 0,17080111 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15809396 0,17072445 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,15809396 0,17064786 ! gastrulation GO:0007369 112 55 0,000 0,15809396 0,17057133 ! RNA elongation GO:0006354 79 55 0,000 0,15809396 0,17049488 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16072649 0,17325625 ! sensory perception of smell GO:0007608 80 56 0,000 0,16072649 0,17317866 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16072649 0,17310114 ! proton transport GO:0015992 94 56 0,000 0,16072649 0,17302369 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16072649 0,17294631 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,16335088 0,17569165 ! lipid modification GO:0030258 97 57 0,000 0,16335088 0,17561315 ! maintenance of location GO:0051235 118 57 0,000 0,16335088 0,17553471 ! hydrogen transport GO:0006818 97 58 0,000 0,16596715 0,1782665 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,16596715 0,17818695 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16596715 0,17810748 ! adult behavior GO:0030534 99 58 0,000 0,16596715 0,17802807 ! positive regulation of secretion GO:0051047 95 59 0,000 0,16857532 0,1807452 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16857532 0,18066469 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,16857532 0,18058425 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16857532 0,18050388 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,16857532 0,18042359 ! DNA catabolic process GO:0006308 86 59 0,000 0,16857532 0,18034336 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,16857532 0,18026321 ! establishment of organelle localization GO:0051656 109 59 0,000 0,16857532 0,18018313 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17117543 0,18288103 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17117543 0,18279986 ! regulation of heart contraction GO:0008016 110 60 0,000 0,17117543 0,18271876 ! camera-type eye development GO:0043010 116 60 0,000 0,17117543 0,18263773 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,17117543 0,18255677 ! kidney development GO:0001822 122 60 0,000 0,17117543 0,18247589 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17376748 0,18515703 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,17376748 0,18507506 ! mesoderm development GO:0007498 119 61 0,000 0,17376748 0,18499317 ! tRNA processing GO:0008033 89 61 0,000 0,17376748 0,18491135 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17376748 0,18482961 ! ear development GO:0043583 103 62 0,000 0,17635152 0,18749526 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17635152 0,18741244 ! gonad development GO:0008406 98 62 0,000 0,17635152 0,1873297 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,17635152 0,18724703 ! regulation of mitosis GO:0007088 105 63 0,000 0,17892757 0,18989842 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,17892757 0,18981469 ! detection of external stimulus GO:0009581 91 63 0,000 0,17892757 0,18973104 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,17892757 0,18964745 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18149564 0,19228468 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18149564 0,19220004 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18149564 0,19211549 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18149564 0,192031 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18149564 0,19194659 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18405576 0,19456861 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18405576 0,19448316 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18405576 0,19439779 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,18405576 0,19431249 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,18405576 0,19422726 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18660796 0,19683418 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18660796 0,19674792 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18660796 0,19666174 ! secondary metabolic process GO:0019748 116 66 0,000 0,18660796 0,19657564 ! developmental maturation GO:0021700 116 66 0,000 0,18660796 0,19648961 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18915227 0,19908152 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18915227 0,19899447 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18915227 0,1989075 ! hexose catabolic process GO:0019320 104 67 0,000 0,18915227 0,1988206 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18915227 0,19873378 ! adaptive immune response GO:0002250 119 67 0,000 0,18915227 0,19864703 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,18915227 0,19856036 ! amino acid transport GO:0006865 125 68 0,000 0,19168869 0,20113519 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19168869 0,20104751 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19168869 0,20095991 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19168869 0,20087239 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19168869 0,20078494 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19421727 0,20334498 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19421727 0,20325653 ! urogenital system development GO:0001655 137 69 0,000 0,19421727 0,20316816 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19421727 0,20307986 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19421727 0,20299164 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19421727 0,2029035 ! appendage morphogenesis GO:0035107 135 70 0,000 0,19673803 0,20544778 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,19925098 0,20798171 ! reproductive structure development GO:0048608 113 71 0,000 0,19925098 0,20789152 ! appendage development GO:0048736 136 71 0,000 0,19925098 0,20780141 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,19925098 0,20771137 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,19925098 0,20762142 ! regulation of immune effector process GO:0002697 137 71 0,000 0,19925098 0,20753154 ! acute inflammatory response GO:0002526 113 72 0,000 0,20175615 0,21004989 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,20175615 0,20995904 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,20175615 0,20986826 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,20175615 0,20977757 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,20175615 0,20968695 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,20425357 0,21219088 ! fertilization GO:0009566 90 73 0,000 0,20425357 0,2120993 ! transition metal ion transport GO:0000041 126 74 0,000 0,20674325 0,21459201 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20674325 0,21449947 ! meiosis GO:0007126 121 74 0,000 0,20674325 0,21440701 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,20674325 0,21431464 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,20674325 0,21422234 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,20674325 0,21413012 ! eye development GO:0001654 143 74 0,000 0,20674325 0,21403798 ! organelle localization GO:0051640 136 74 0,000 0,20674325 0,21394592 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20922523 0,21642129 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20922523 0,21632828 ! meiotic cell cycle GO:0051321 122 75 0,000 0,20922523 0,21623536 ! rhythmic process GO:0048511 128 75 0,000 0,20922523 0,21614251 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21169953 0,21860475 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,21169953 0,21851097 ! defense response to bacterium GO:0042742 89 76 0,000 0,21169953 0,21841727 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21169953 0,21832365 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21169953 0,21823011 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21416617 0,22067829 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,21416617 0,22058382 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,21416617 0,22048943 ! blood coagulation GO:0007596 146 78 0,000 0,21662517 0,22292564 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21662517 0,22283034 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,21907656 0,22525564 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21907656 0,22515942 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,21907656 0,22506328 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,21907656 0,22496722 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,21907656 0,22487124 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,22152035 0,22728272 ! response to metal ion GO:0010038 140 80 0,000 0,22152035 0,22718584 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22152035 0,22708904 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22152035 0,22699232 ! inorganic anion transport GO:0015698 138 80 0,000 0,22152035 0,22689569 ! digestion GO:0007586 112 81 0,000 0,22395659 0,22929342 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,22395659 0,22919589 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,22638527 0,2315829 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,22638527 0,23148447 ! response to nutrient GO:0007584 125 82 0,000 0,22638527 0,23138614 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,22638527 0,23128789 ! regulation of lyase activity GO:0051339 160 83 0,000 0,22880644 0,23366227 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,23122011 0,23602698 ! hemostasis GO:0007599 158 84 0,000 0,23122011 0,23592688 ! negative regulation of transport GO:0051051 153 84 0,000 0,23122011 0,23582687 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23122011 0,23572695 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23122011 0,2356271 ! response to unfolded protein GO:0006986 131 85 0,000 0,23362631 0,23797837 ! nucleosome assembly GO:0006334 122 85 0,000 0,23362631 0,23787766 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,23362631 0,23777703 ! amine biosynthetic process GO:0009309 138 86 0,000 0,23602506 0,24011682 ! response to inorganic substance GO:0010035 153 86 0,000 0,23602506 0,24001534 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,23602506 0,23991393 ! chromatin assembly GO:0031497 124 86 0,000 0,23602506 0,23981262 ! tube morphogenesis GO:0035239 176 86 0,000 0,23602506 0,23971139 ! alcohol catabolic process GO:0046164 130 86 0,000 0,23602506 0,23961025 ! amine transport GO:0015837 155 86 0,000 0,23602506 0,23950919 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,23841637 0,24183381 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,23841637 0,2417319 ! cellular respiration GO:0045333 135 88 0,000 0,24080028 0,24404612 ! regulation of neurological system process GO:0031644 148 88 0,000 0,24080028 0,24394336 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,24080028 0,24384069 ! cellular defense response GO:0006968 114 89 0,000 0,24317681 0,24614363 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,24554598 0,24843719 ! sex differentiation GO:0007548 145 90 0,000 0,24554598 0,24833276 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,24554598 0,24822842 ! sterol metabolic process GO:0016125 152 91 0,000 0,24790781 0,25051079 ! response to protein stimulus GO:0051789 149 91 0,000 0,24790781 0,25040562 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,24790781 0,25030054 ! regulation of defense response GO:0031347 149 92 0,000 0,25026233 0,25257179 ! nucleosome organization GO:0034728 138 92 0,000 0,25026233 0,25246589 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25026233 0,25236008 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25026233 0,25225436 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,25260955 0,25451364 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,25260955 0,2544071 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25260955 0,25430066 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,25260955 0,2541943 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,2549495 0,25644168 ! female pregnancy GO:0007565 164 94 0,000 0,2549495 0,25633452 ! transcription initiation GO:0006352 153 94 0,000 0,2549495 0,25622744 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,2572822 0,25846387 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25960768 0,26069118 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,25960768 0,26058243 ! detection of stimulus GO:0051606 151 96 0,000 0,25960768 0,26047376 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26192595 0,26269022 ! protein ubiquitination GO:0016567 217 97 0,000 0,26192595 0,26258077 ! hormone metabolic process GO:0042445 157 97 0,000 0,26192595 0,2624714 ! response to virus GO:0009615 160 98 0,000 0,26423704 0,26467707 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,26423704 0,26456693 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,26423704 0,26445688 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,26654098 0,2666518 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,26654098 0,26654098