pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6222-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycine metabolic process GO:0006544 28 17 5,000 1,841E-10 4,428E-07 ! one-carbon metabolic process GO:0006730 154 85 8,000 5,268E-10 6,337E-07 ! glycine biosynthetic process GO:0006545 7 5 3,000 3,189E-09 2,558E-06 ! serine family amino acid metabolic process GO:0009069 49 31 5,000 1,033E-08 6,211E-06 ! regulation of helicase activity GO:0051095 15 7 3,000 2,215E-08 1,066E-05 ! regulation of DNA metabolic process GO:0051052 178 97 7,000 3,639E-08 1,459E-05 ! serine family amino acid biosynthetic process GO:0009070 17 13 3,000 4,418E-07 1,519E-04 ! positive regulation of helicase activity GO:0051096 11 5 2,000 1,276E-06 3,838E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 1,276E-06 3,411E-04 ! negative regulation of DNA recombination GO:0045910 15 7 2,000 4,433E-06 1,067E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 7,066E-06 1,546E-03 ! regulation of DNA replication GO:0006275 101 56 4,000 9,822E-06 1,969E-03 ! synaptic vesicle endocytosis GO:0048488 20 9 2,000 1,056E-05 1,954E-03 ! protein sumoylation GO:0016925 15 10 2,000 1,503E-05 2,583E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 2,735E-05 4,387E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 3,000 2,966E-05 4,46E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 4,491E-05 6,356E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 6,858E-05 9,167E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 8,113E-05 0,0102738 ! pigmentation GO:0043473 100 46 3,000 8,851E-05 0,01064757 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 1,173E-04 0,01344487 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 2,000 1,173E-04 0,01283374 ! cellular amino acid biosynthetic process GO:0008652 75 51 3,000 1,329E-04 0,01390208 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,375E-04 0,01378878 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,599E-04 0,01538597 ! positive regulation of locomotion GO:0040017 39 21 2,000 1,599E-04 0,0147942 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! cellular aldehyde metabolic process GO:0006081 34 22 2,000 1,844E-04 0,0164343 ! regulation of chemotaxis GO:0050920 40 22 2,000 1,844E-04 0,01584736 ! somatic diversification of immunoglobulins GO:0016445 50 22 2,000 1,844E-04 0,0153009 ! positive regulation of DNA replication GO:0045740 43 23 2,000 2,113E-04 0,01694623 ! regulation of DNA recombination GO:0000018 48 23 2,000 2,113E-04 0,01639958 ! synaptic vesicle transport GO:0048489 46 23 2,000 2,113E-04 0,01588709 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 2,000 2,406E-04 0,01754099 GO:0016444|somatic cell DNA recombination, ! regulation of behavior GO:0050795 43 24 2,000 2,406E-04 0,01702508 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 2,503E-04 0,01720592 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 2,538E-04 0,01696518 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,538E-04 0,01650666 ! Notch receptor processing GO:0007220 8 5 1,000 2,538E-04 0,01607227 ! apoptotic cell clearance GO:0043277 20 5 1,000 2,538E-04 0,01566016 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 2,538E-04 0,01526866 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,538E-04 0,01489625 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,538E-04 0,01454158 ! neural tube patterning GO:0021532 7 5 1,000 2,538E-04 0,0142034 ! positive regulation of blood coagulation GO:0030194 11 5 1,000 2,538E-04 0,0138806 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 2,538E-04 0,01357214 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 2,538E-04 0,01327709 ! phospholipid scrambling GO:0017121 8 5 1,000 2,538E-04 0,0129946 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 2,724E-04 0,01365295 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 2,724E-04 0,01337432 ! immunoglobulin production GO:0002377 55 25 2,000 2,724E-04 0,01310683 GO:0002440|production of molecular mediator of immune response, ! regulation of blood coagulation GO:0030193 40 25 2,000 2,724E-04 0,01284983 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 3,068E-04 0,0141936 ! somatic diversification of immune receptors GO:0002200 56 26 2,000 3,068E-04 0,01392579 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,438E-04 0,01531925 ! regulation of chromosome organization GO:0033044 42 27 2,000 3,438E-04 0,01504072 ! negative regulation of platelet activation GO:0010544 9 6 1,000 3,795E-04 0,01630466 GO:0010543|regulation of platelet activation, ! establishment of spindle localization GO:0051293 12 6 1,000 3,795E-04 0,01601861 GO:0051653|spindle localization, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 3,795E-04 0,01574243 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 1,000 3,795E-04 0,01547561 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 1,000 3,795E-04 0,01521768 ! determination of adult lifespan GO:0008340 15 6 1,000 3,795E-04 0,01496821 ! positive regulation of coagulation GO:0050820 12 6 1,000 3,795E-04 0,01472679 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 3,837E-04 0,01465184 ! regulation of coagulation GO:0050818 46 29 2,000 4,263E-04 0,01602733 ! neuron adhesion GO:0007158 12 7 1,000 5,295E-04 0,01960029 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,295E-04 0,01930332 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 5,295E-04 0,01901521 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 5,295E-04 0,01873557 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 1,000 5,295E-04 0,01846404 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,295E-04 0,01820027 ! B cell lineage commitment GO:0002326 21 7 1,000 5,295E-04 0,01794393 ! negative regulation of focal adhesion formation GO:0051895 20 7 1,000 5,295E-04 0,01769471 ! T cell lineage commitment GO:0002360 16 7 1,000 5,295E-04 0,01745231 ! regulation of lipid transport GO:0032368 14 7 1,000 5,295E-04 0,01721647 ! response to tumor cell GO:0002347 13 7 1,000 5,295E-04 0,01698692 ! axonal fasciculation GO:0007413 18 7 1,000 5,295E-04 0,01676341 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 5,295E-04 0,0165457 GO:0002688|regulation of leukocyte chemotaxis, ! learning or memory GO:0007611 147 73 3,000 5,308E-04 0,01637431 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 5,723E-04 0,01742933 ! DNA damage checkpoint GO:0000077 71 33 2,000 6,272E-04 0,01886234 ! mismatch repair GO:0006298 46 34 2,000 6,853E-04 0,02035652 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 7,037E-04 0,02064664 GO:0016446|somatic hypermutation of immunoglobulin genes, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,037E-04 0,02039789 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,037E-04 0,02015506 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 7,037E-04 0,01991794 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 1,000 7,037E-04 0,01968633 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 7,037E-04 0,01946005 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,037E-04 0,01923892 ! multicellular organismal aging GO:0010259 18 8 1,000 7,037E-04 0,01902275 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 7,037E-04 0,01881139 ! regulation of macrophage activation GO:0043030 15 8 1,000 7,037E-04 0,01860467 ! negative regulation of organic acid transport GO:0032891 13 8 1,000 7,037E-04 0,01840244 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 1,000 7,037E-04 0,01820457 ! DNA integrity checkpoint GO:0031570 75 36 2,000 8,117E-04 0,02077493 ! negative regulation of cell activation GO:0050866 65 36 2,000 8,117E-04 0,02055625 ! meiosis I GO:0007127 65 37 2,000 8,8E-04 0,02205493 ! pentose-phosphate shunt GO:0006098 16 9 1,000 9,017E-04 0,02236585 GO:0006740|NADPH regeneration, ! RNA methylation GO:0001510 15 9 1,000 9,017E-04 0,02213762 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,017E-04 0,02191401 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 9,017E-04 0,02169487 ! motor axon guidance GO:0008045 16 9 1,000 9,017E-04 0,02148007 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 9,017E-04 0,02126948 ! regulation of fibrinolysis GO:0051917 16 9 1,000 9,017E-04 0,02106298 ! regulation of telomere maintenance GO:0032204 14 9 1,000 9,017E-04 0,02086045 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 9,519E-04 0,02181174 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 9,519E-04 0,02160597 ! amine biosynthetic process GO:0009309 138 86 3,000 9,842E-04 0,02213026 ! learning GO:0007612 77 39 2,000 1,027E-03 0,02288788 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 1,123E-03 0,0247965 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,123E-03 0,02457108 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,123E-03 0,02434972 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 1,123E-03 0,02413231 ! L-serine metabolic process GO:0006563 18 10 1,000 1,123E-03 0,02391875 ! phagocytosis, engulfment GO:0006911 28 10 1,000 1,123E-03 0,02370894 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,123E-03 0,02350277 ! apical protein localization GO:0045176 15 10 1,000 1,123E-03 0,02330016 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,123E-03 0,02310102 ! midbrain development GO:0030901 13 10 1,000 1,123E-03 0,02290524 ! detection of calcium ion GO:0005513 23 10 1,000 1,123E-03 0,02271276 ! T cell differentiation GO:0030217 81 41 2,000 1,19E-03 0,02384969 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,317E-03 0,02617917 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 2,000 1,367E-03 0,02695721 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,367E-03 0,02673804 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,368E-03 0,02655192 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,368E-03 0,0263395 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,368E-03 0,02613046 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,368E-03 0,02592471 ! substrate-bound cell migration GO:0006929 13 11 1,000 1,368E-03 0,02572217 ! DNA methylation GO:0006306 19 11 1,000 1,368E-03 0,02552277 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,368E-03 0,02532644 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 1,368E-03 0,02513311 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! regulation of organic acid transport GO:0032890 18 11 1,000 1,368E-03 0,02494271 ! biopolymer methylation GO:0043414 84 44 2,000 1,461E-03 0,02643877 ! detection of stimulus GO:0051606 151 96 3,000 1,48E-03 0,02658199 ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 1,56E-03 0,02780431 ! positive regulation of blood pressure GO:0045777 17 12 1,000 1,637E-03 0,02895416 ! folic acid and derivative biosynthetic process GO:0009396 21 12 1,000 1,637E-03 0,02874281 ! focal adhesion formation GO:0048041 35 12 1,000 1,637E-03 0,02853453 ! negative regulation of endothelial cell migration GO:0010596 25 12 1,000 1,637E-03 0,02832925 ! asymmetric protein localization GO:0008105 20 12 1,000 1,637E-03 0,02812689 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,637E-03 0,02792741 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of interleukin-12 production GO:0032655 19 12 1,000 1,637E-03 0,02773074 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 1,637E-03 0,02753682 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 1,637E-03 0,02734559 ! spleen development GO:0048536 22 12 1,000 1,637E-03 0,027157 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,637E-03 0,026971 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell migration GO:0030336 115 46 2,000 1,663E-03 0,02721498 ! cell cycle arrest GO:0007050 213 100 3,000 1,72E-03 0,02796803 ! response to calcium ion GO:0051592 81 47 2,000 1,77E-03 0,02857425 ! methylation GO:0032259 90 47 2,000 1,77E-03 0,02838376 ! activation of caspase activity GO:0006919 84 48 2,000 1,881E-03 0,02996428 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 1,928E-03 0,03051466 ! endocrine pancreas development GO:0031018 22 13 1,000 1,928E-03 0,03031522 ! plasma membrane organization GO:0007009 24 13 1,000 1,928E-03 0,03011836 ! response to X-ray GO:0010165 25 13 1,000 1,928E-03 0,02992405 ! regulation of cellular pH GO:0030641 22 13 1,000 1,928E-03 0,02973223 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,928E-03 0,02954285 ! detection of abiotic stimulus GO:0009582 74 49 2,000 1,996E-03 0,03039157 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,115E-03 0,03200936 ! pteridine and derivative biosynthetic process GO:0042559 19 14 1,000 2,242E-03 0,03370785 ! response to gamma radiation GO:0010332 28 14 1,000 2,242E-03 0,03349849 ! NADP metabolic process GO:0006739 24 14 1,000 2,242E-03 0,03329171 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,242E-03 0,03308746 ! regulation of angiogenesis GO:0045765 114 52 2,000 2,368E-03 0,03473369 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,5E-03 0,0364594 ! response to UV GO:0009411 104 53 2,000 2,5E-03 0,03623976 ! response to hexose stimulus GO:0009746 22 15 1,000 2,578E-03 0,03713943 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 1,000 2,578E-03 0,03691836 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,578E-03 0,03669991 ! regulation of exocytosis GO:0017157 22 15 1,000 2,578E-03 0,03648403 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,578E-03 0,03627067 ! mRNA splice site selection GO:0006376 38 15 1,000 2,578E-03 0,0360598 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,78E-03 0,03865601 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 2,78E-03 0,03843385 ! negative regulation of cell motion GO:0051271 134 55 2,000 2,78E-03 0,03821423 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,936E-03 0,04014064 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 2,936E-03 0,03991386 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,936E-03 0,03968963 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,936E-03 0,0394679 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! neuron recognition GO:0008038 35 16 1,000 2,936E-03 0,03924863 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,077E-03 0,04090403 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,317E-03 0,04384673 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,317E-03 0,04360713 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,317E-03 0,04337013 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,317E-03 0,0431357 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 3,317E-03 0,04290379 ! folic acid and derivative metabolic process GO:0006760 33 17 1,000 3,317E-03 0,04267436 ! aromatic compound biosynthetic process GO:0019438 24 17 1,000 3,317E-03 0,04244737 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,559E-03 0,0453079 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 3,719E-03 0,04709361 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 3,719E-03 0,04684705 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,719E-03 0,04660306 ! aromatic compound catabolic process GO:0019439 27 18 1,000 3,719E-03 0,04636159 ! regulation of homeostatic process GO:0032844 134 62 2,000 3,905E-03 0,04842479 ! detection of external stimulus GO:0009581 91 63 2,000 4,085E-03 0,05039887 ! positive regulation of translation GO:0045727 30 19 1,000 4,143E-03 0,05085332 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 4,143E-03 0,05059518 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 4,143E-03 0,05033965 ! forelimb morphogenesis GO:0035136 32 19 1,000 4,143E-03 0,05008669 ! cellular response to unfolded protein GO:0034620 33 19 1,000 4,143E-03 0,04983625 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 4,143E-03 0,04958831 ! neuromuscular junction development GO:0007528 34 19 1,000 4,143E-03 0,04934283 ! response to lipopolysaccharide GO:0032496 30 19 1,000 4,143E-03 0,04909976 ! peptide cross-linking GO:0018149 37 19 1,000 4,143E-03 0,04885907 ! cellular pigmentation GO:0033059 36 19 1,000 4,143E-03 0,04862074 ! G1 phase GO:0051318 40 19 1,000 4,143E-03 0,04838471 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,143E-03 0,04815097 ! proximal/distal pattern formation GO:0009954 32 19 1,000 4,143E-03 0,04791947 ! positive regulation of cell motion GO:0051272 146 64 2,000 4,27E-03 0,04915371 ! pteridine and derivative metabolic process GO:0042558 29 20 1,000 4,588E-03 0,05256168 ! response to alkaloid GO:0043279 38 20 1,000 4,588E-03 0,05231257 ! retinoid metabolic process GO:0001523 32 20 1,000 4,588E-03 0,05206582 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 1,000 4,588E-03 0,05182138 ! response to carbohydrate stimulus GO:0009743 29 20 1,000 4,588E-03 0,05157922 ! cellular response to starvation GO:0009267 33 20 1,000 4,588E-03 0,05133932 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 4,588E-03 0,05110163 ! detection of chemical stimulus GO:0009593 37 20 1,000 4,588E-03 0,05086614 ! negative regulation of T cell activation GO:0050868 40 20 1,000 4,588E-03 0,05063281 ! negative regulation of coagulation GO:0050819 29 20 1,000 4,588E-03 0,05040161 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 4,588E-03 0,05017251 ! secondary metabolic process GO:0019748 116 66 2,000 4,655E-03 0,0506793 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 4,855E-03 0,05262147 ! chromosome segregation GO:0007059 113 67 2,000 4,855E-03 0,0523855 ! adaptive immune response GO:0002250 119 67 2,000 4,855E-03 0,05215164 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,054E-03 0,05404157 ! cell aging GO:0007569 44 21 1,000 5,054E-03 0,05380245 ! DNA modification GO:0006304 34 21 1,000 5,054E-03 0,05356543 ! terpenoid metabolic process GO:0006721 37 21 1,000 5,054E-03 0,0533305 ! negative regulation of kinase activity GO:0033673 131 68 2,000 5,061E-03 0,05317098 ! cell cycle checkpoint GO:0000075 137 69 2,000 5,271E-03 0,0551425 ! glutamate signaling pathway GO:0007215 41 22 1,000 5,541E-03 0,05770959 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 5,541E-03 0,05746084 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 5,541E-03 0,05721423 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 5,541E-03 0,05696973 ! apoptotic nuclear changes GO:0030262 32 22 1,000 5,541E-03 0,0567273 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 5,541E-03 0,05648693 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 5,541E-03 0,05624859 ! B cell activation GO:0042113 160 71 2,000 5,708E-03 0,05770443 ! regulation of caspase activity GO:0043281 122 72 2,000 5,934E-03 0,0597409 ! negative regulation of transferase activity GO:0051348 140 72 2,000 5,934E-03 0,05949198 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,048E-03 0,0603822 ! gluconeogenesis GO:0006094 33 23 1,000 6,048E-03 0,06013268 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,048E-03 0,05988522 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,048E-03 0,05963979 ! sex determination GO:0007530 47 23 1,000 6,048E-03 0,05939636 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 6,048E-03 0,05915492 ! negative regulation of cytokine production GO:0001818 40 23 1,000 6,048E-03 0,05891542 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 6,048E-03 0,05867786 ! axon guidance GO:0007411 139 73 2,000 6,166E-03 0,05957934 ! meiosis GO:0007126 121 74 2,000 6,403E-03 0,06162108 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,403E-03 0,06137558 ! eye development GO:0001654 143 74 2,000 6,403E-03 0,06113203 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,576E-03 0,06253915 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,576E-03 0,06229293 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 6,576E-03 0,06204865 ! protein tetramerization GO:0051262 52 24 1,000 6,576E-03 0,06180627 ! meiotic cell cycle GO:0051321 122 75 2,000 6,645E-03 0,06221088 ! lymphocyte differentiation GO:0030098 167 75 2,000 6,645E-03 0,06196975 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 7,124E-03 0,06618255 ! myelination GO:0042552 45 25 1,000 7,124E-03 0,065928 ! phototransduction GO:0007602 33 25 1,000 7,124E-03 0,0656754 ! vasculogenesis GO:0001570 46 25 1,000 7,124E-03 0,06542473 ! negative regulation of DNA replication GO:0008156 42 25 1,000 7,124E-03 0,06517597 ! response to starvation GO:0042594 42 25 1,000 7,124E-03 0,06492909 ! negative regulation of cell development GO:0010721 73 25 1,000 7,124E-03 0,06468408 GO:0050768|negative regulation of neurogenesis, ! cellular response to nutrient levels GO:0031669 41 25 1,000 7,124E-03 0,0644409 ! protein oligomerization GO:0051259 139 78 2,000 7,404E-03 0,06672332 ! regulation of peptidase activity GO:0052547 134 79 2,000 7,668E-03 0,0688447 ! pyruvate metabolic process GO:0006090 38 26 1,000 7,693E-03 0,06880377 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 7,693E-03 0,06854894 ! cellular response to oxidative stress GO:0034599 39 26 1,000 7,693E-03 0,068296 ! positive regulation of nuclear division GO:0051785 40 26 1,000 7,693E-03 0,06804491 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 7,693E-03 0,06779566 ! response to metal ion GO:0010038 140 80 2,000 7,938E-03 0,06970393 ! T cell activation GO:0042110 168 81 2,000 8,213E-03 0,07185703 ! response to hypoxia GO:0001666 171 81 2,000 8,213E-03 0,07159668 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 8,28E-03 0,07192308 ! mitochondrial membrane organization GO:0007006 57 27 1,000 8,28E-03 0,07166436 ! male gonad development GO:0008584 44 27 1,000 8,28E-03 0,0714075 ! base-excision repair GO:0006284 41 27 1,000 8,28E-03 0,07115247 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 8,28E-03 0,07089926 ! response to drug GO:0042493 143 82 2,000 8,494E-03 0,07246757 ! response to oxygen levels GO:0070482 176 83 2,000 8,78E-03 0,07464469 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 8,888E-03 0,07529649 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 1,000 8,888E-03 0,07503229 ! regulation of pH GO:0006885 43 29 1,000 9,515E-03 0,08004278 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 9,515E-03 0,07976389 ! respiratory gaseous exchange GO:0007585 57 29 1,000 9,515E-03 0,07948693 ! detection of light stimulus GO:0009583 38 29 1,000 9,515E-03 0,07921189 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 9,515E-03 0,07893875 ! response to inorganic substance GO:0010035 153 86 2,000 9,672E-03 0,07997015 ! mitochondrion organization GO:0007005 148 86 2,000 9,672E-03 0,07969628 ! cell junction assembly GO:0034329 78 30 1,000 0,01016055 0,08343444 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01016055 0,08315064 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 1,000 0,01016055 0,08286878 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01016055 0,08258882 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01016055 0,08231074 ! response to heat GO:0009408 50 30 1,000 0,01016055 0,08203453 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01061549 0,08542094 ! alkaloid metabolic process GO:0009820 53 31 1,000 0,01082538 0,08681954 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01082538 0,08653111 ! spliceosome assembly GO:0000245 67 32 1,000 0,01150892 0,09169026 ! spindle organization GO:0007051 46 32 1,000 0,01150892 0,09138765 ! metanephros development GO:0001656 74 32 1,000 0,01150892 0,09108704 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01150892 0,09078839 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01150892 0,0904917 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01150892 0,09019694 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01150892 0,08990409 ! hindbrain development GO:0030902 61 32 1,000 0,01150892 0,08961314 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,0119534 0,09277383 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01221097 0,09446812 ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 0,01221097 0,09416534 ! transcription initiation GO:0006352 153 94 2,000 0,01230232 0,09456668 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01301757 0,09974607 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01366978 0,10441105 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01366978 0,10408064 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01366978 0,10375231 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01442614 0,10914869 ! cell junction organization GO:0034330 86 36 1,000 0,01442614 0,10880653 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01442614 0,10846651 ! sister chromatid segregation GO:0000819 58 37 1,000 0,0152002 0,11393048 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,0152002 0,11357666 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,0152002 0,11322503 ! nucleus organization GO:0006997 67 38 1,000 0,01599177 0,11875373 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,01599177 0,11838834 ! mammary gland development GO:0030879 86 39 1,000 0,01680066 0,12399506 ! ear morphogenesis GO:0042471 60 39 1,000 0,01680066 0,12361587 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01680066 0,12323899 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01680066 0,12286441 ! RNA modification GO:0009451 57 39 1,000 0,01680066 0,12249209 ! cytokinesis GO:0000910 72 40 1,000 0,01762667 0,12812615 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,0184696 0,13384894 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,0184696 0,13344699 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0184696 0,13304745 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,0184696 0,13265029 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01932926 0,13841133 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01932926 0,13800061 ! neuron migration GO:0001764 79 42 1,000 0,01932926 0,13759233 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01932926 0,13718645 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02020548 0,14298345 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02020548 0,14256414 ! glucose transport GO:0015758 65 43 1,000 0,02020548 0,14214729 ! neural tube development GO:0021915 77 43 1,000 0,02020548 0,14173287 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,02020548 0,14132085 ! phagocytosis GO:0006909 90 43 1,000 0,02020548 0,14091123 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,02020548 0,14050397 ! hexose transport GO:0008645 67 44 1,000 0,02109805 0,14628789 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02109805 0,14586752 ! male sex differentiation GO:0046661 76 44 1,000 0,02109805 0,14544956 ! double-strand break repair GO:0006302 81 44 1,000 0,02109805 0,14503399 ! B cell differentiation GO:0030183 107 44 1,000 0,02109805 0,14462079 ! glycolysis GO:0006096 65 45 1,000 0,02200679 0,15042139 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 0,02200679 0,14999527 ! cell growth GO:0016049 84 45 1,000 0,02200679 0,14957156 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02293152 0,15541754 ! response to insulin stimulus GO:0032868 95 46 1,000 0,02293152 0,15498098 ! protein homooligomerization GO:0051260 76 47 1,000 0,02387205 0,16088556 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,0248282 0,16686215 ! mitochondrial transport GO:0006839 82 48 1,000 0,0248282 0,16639735 ! Notch signaling pathway GO:0007219 96 48 1,000 0,0248282 0,16593513 ! cellular component disassembly GO:0022411 86 48 1,000 0,0248282 0,16547548 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0248282 0,16501836 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,0248282 0,16456377 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02514581 0,16621107 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02514581 0,16575569 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02514581 0,16530281 ! neuron fate determination GO:0048664 7 5 0,000 0,02514581 0,16485239 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02514581 0,16440443 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02514581 0,16395889 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02514581 0,16351575 ! polyol transport GO:0015791 12 5 0,000 0,02514581 0,16307501 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02514581 0,16263664 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02514581 0,16220061 ! response to superoxide GO:0000303 10 5 0,000 0,02514581 0,16176692 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02514581 0,16133554 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02514581 0,16090646 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02514581 0,16047965 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02514581 0,1600551 ! female meiosis GO:0007143 7 5 0,000 0,02514581 0,15963279 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02514581 0,15921271 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02514581 0,15879483 ! cobalt ion transport GO:0006824 11 5 0,000 0,02514581 0,15837913 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02514581 0,15796561 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02514581 0,15755424 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02514581 0,15714501 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02514581 0,1567379 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02514581 0,15633289 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02514581 0,15592997 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02514581 0,15552912 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02514581 0,15513033 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02514581 0,15473358 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02514581 0,15433885 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02514581 0,15394613 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02514581 0,1535554 ! negative chemotaxis GO:0050919 14 5 0,000 0,02514581 0,15316665 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02514581 0,15277987 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02514581 0,15239503 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02514581 0,15201213 ! behavioral response to pain GO:0048266 9 5 0,000 0,02514581 0,15163115 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02514581 0,15125207 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02514581 0,15087488 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02514581 0,15049957 ! micturition GO:0060073 9 5 0,000 0,02514581 0,15012613 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02514581 0,14975453 ! copulation GO:0007620 9 5 0,000 0,02514581 0,14938476 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02514581 0,14901682 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02514581 0,14865068 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02514581 0,14828634 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02514581 0,14792379 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02514581 0,147563 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02514581 0,14720396 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02514581 0,14684667 ! grooming behavior GO:0007625 6 5 0,000 0,02514581 0,14649111 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02514581 0,14613727 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02514581 0,14578513 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02514581 0,14543468 ! response to protozoan GO:0001562 10 5 0,000 0,02514581 0,14508592 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02514581 0,14473882 ! lymph vessel development GO:0001945 10 5 0,000 0,02514581 0,14439339 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02514581 0,14404959 ! endochondral ossification GO:0001958 16 5 0,000 0,02514581 0,14370743 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02514581 0,14336689 ! parathyroid gland development GO:0060017 13 5 0,000 0,02514581 0,14302796 ! anagen GO:0042640 6 5 0,000 0,02514581 0,14269063 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02514581 0,14235489 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02514581 0,14202072 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02514581 0,14168812 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02514581 0,14135708 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02514581 0,14102757 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02514581 0,1406996 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02514581 0,14037315 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02514581 0,14004821 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02514581 0,13972478 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02514581 0,13940283 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02514581 0,13908236 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02514581 0,13876337 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02514581 0,13844583 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02514581 0,13812975 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02514581 0,1378151 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02514581 0,13750188 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02514581 0,13719009 ! histidine catabolic process GO:0006548 6 5 0,000 0,02514581 0,1368797 GO:0009077|histidine family amino acid catabolic process, ! microvillus organization GO:0032528 7 5 0,000 0,02514581 0,13657072 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02514581 0,13626313 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02514581 0,13595692 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02514581 0,13565208 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02514581 0,13534861 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02514581 0,13504649 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02514581 0,13474572 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02514581 0,13444629 ! polyol catabolic process GO:0046174 7 5 0,000 0,02514581 0,13414818 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02514581 0,13385139 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02514581 0,13355591 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02514581 0,13326174 ! muscle cell migration GO:0014812 8 5 0,000 0,02514581 0,13296885 ! mitochondrial fission GO:0000266 8 5 0,000 0,02514581 0,13267726 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02514581 0,13238693 ! mRNA transcription GO:0009299 9 5 0,000 0,02514581 0,13209788 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02514581 0,13181008 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02514581 0,13152354 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02514581 0,13123824 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02514581 0,13095417 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02514581 0,13067134 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02514581 0,13038972 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02514581 0,13010931 ! response to food GO:0032094 6 5 0,000 0,02514581 0,1298301 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02514581 0,1295521 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02514581 0,12927527 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02514581 0,12899963 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02514581 0,12872517 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02514581 0,12845187 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02514581 0,12817972 ! forebrain neuron development GO:0021884 13 5 0,000 0,02514581 0,12790873 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02514581 0,12763888 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02514581 0,12737017 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02514581 0,12710258 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02514581 0,12683612 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02514581 0,12657077 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02514581 0,12630653 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02514581 0,12604339 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02514581 0,12578135 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02514581 0,12552039 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02514581 0,12526051 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02514581 0,12500171 ! basic amino acid transport GO:0015802 11 5 0,000 0,02514581 0,12474398 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02514581 0,1244873 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02514581 0,12423168 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02514581 0,12397711 ! depyrimidination GO:0045008 10 5 0,000 0,02514581 0,12372358 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02514581 0,12347108 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02514581 0,12321961 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02514581 0,12296916 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02514581 0,12271973 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02514581 0,12247131 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02514581 0,1222239 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02514581 0,12197748 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02514581 0,12173205 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02514581 0,12148761 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02514581 0,12124415 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02514581 0,12100166 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02514581 0,12076014 ! response to arsenic GO:0046685 10 5 0,000 0,02514581 0,12051958 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02514581 0,12027998 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02514581 0,12004133 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02514581 0,11980362 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02514581 0,11956686 ! response to cadmium ion GO:0046686 7 5 0,000 0,02514581 0,11933102 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02514581 0,11909612 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02514581 0,11886214 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02514581 0,11862908 ! decidualization GO:0046697 11 5 0,000 0,02514581 0,11839692 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02514581 0,11816568 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02514581 0,11793534 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02514581 0,11770589 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02514581 0,11747734 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02514581 0,11724967 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02514581 0,11702288 ! embryonic cleavage GO:0040016 6 5 0,000 0,02514581 0,11679697 ! peroxisome fission GO:0016559 5 5 0,000 0,02514581 0,11657192 ! histone demethylation GO:0016577 10 5 0,000 0,02514581 0,11634775 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02514581 0,11612443 ! mitotic recombination GO:0006312 9 5 0,000 0,02514581 0,11590197 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02514581 0,11568036 ! metaphase plate congression GO:0051310 7 5 0,000 0,02514581 0,1154596 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02514581 0,11523967 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02514581 0,11502059 ! enteric nervous system development GO:0048484 8 5 0,000 0,02514581 0,11480233 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02514581 0,1145849 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02514581 0,1143683 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02514581 0,11415251 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02514581 0,11393753 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02514581 0,11372336 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02514581 0,11351 ! plasminogen activation GO:0031639 5 5 0,000 0,02514581 0,11329743 ! B cell homeostasis GO:0001782 13 5 0,000 0,02514581 0,11308566 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02514581 0,11287468 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02514581 0,11266449 ! metaphase GO:0051323 8 5 0,000 0,02514581 0,11245507 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02514581 0,11224644 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02514581 0,11203857 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02514581 0,11183148 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02514581 0,11162515 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02514581 0,11141957 ! response to redox state GO:0051775 5 5 0,000 0,02514581 0,11121476 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02514581 0,11101069 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02514581 0,11080738 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02514581 0,11060481 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02514581 0,11040297 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02514581 0,11020187 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02514581 0,11000151 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02514581 0,10980187 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02514581 0,10960295 ! striatum development GO:0021756 9 5 0,000 0,02514581 0,10940475 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02514581 0,10920727 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02514581 0,1090105 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02514581 0,10881444 ! glial cell migration GO:0008347 11 5 0,000 0,02514581 0,10861908 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02514581 0,10842442 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02514581 0,10823046 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02514581 0,10803719 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02514581 0,10784461 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02514581 0,10765272 ! neuroprotection GO:0043526 6 5 0,000 0,02514581 0,10746151 ! neural plate development GO:0001840 8 5 0,000 0,02514581 0,10727097 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02514581 0,10708111 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02514581 0,10689192 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02514581 0,1067034 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02514581 0,10651554 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02514581 0,10632835 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02514581 0,1061418 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02514581 0,10595592 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02514581 0,10577068 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02514581 0,10558609 ! spindle assembly GO:0051225 6 5 0,000 0,02514581 0,10540214 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02514581 0,10521883 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02514581 0,10503616 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02514581 0,10485412 ! drug metabolic process GO:0017144 6 5 0,000 0,02514581 0,10467271 ! stem cell division GO:0017145 11 5 0,000 0,02514581 0,10449193 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02514581 0,10431177 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02514581 0,10413224 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02514581 0,10395331 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02514581 0,10377501 ! regulation of action potential GO:0001508 95 49 1,000 0,02579979 0,10629161 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02579979 0,10610991 ! endocrine system development GO:0035270 104 49 1,000 0,02579979 0,10592884 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,02579979 0,10574838 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,02579979 0,10556853 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02678664 0,10942048 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02678664 0,10923503 ! vesicle organization GO:0016050 107 51 1,000 0,02778858 0,11312914 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02778858 0,11293804 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,02778858 0,11274759 ! synapse organization GO:0050808 85 52 1,000 0,02880542 0,1166765 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03009908 0,12171157 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03009908 0,12150735 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03009908 0,12130382 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03009908 0,12110097 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03009908 0,1208988 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03009908 0,1206973 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03009908 0,12049648 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03009908 0,12029632 ! sleep GO:0030431 13 6 0,000 0,03009908 0,12009682 ! response to oxygen radical GO:0000305 11 6 0,000 0,03009908 0,11989798 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03009908 0,11969981 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03009908 0,11950228 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03009908 0,11930541 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03009908 0,11910918 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03009908 0,1189136 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03009908 0,11871866 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03009908 0,11852436 ! forebrain regionalization GO:0021871 8 6 0,000 0,03009908 0,11833069 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03009908 0,11813765 ! male meiosis GO:0007140 7 6 0,000 0,03009908 0,11794525 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03009908 0,11775347 ! response to zinc ion GO:0010043 9 6 0,000 0,03009908 0,11756231 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03009908 0,11737177 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03009908 0,11718185 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03009908 0,11699254 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03009908 0,11680384 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03009908 0,11661575 ! malate metabolic process GO:0006108 11 6 0,000 0,03009908 0,11642827 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03009908 0,11624138 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03009908 0,1160551 ! protein refolding GO:0042026 15 6 0,000 0,03009908 0,11586941 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03009908 0,11568432 ! opsonization GO:0008228 8 6 0,000 0,03009908 0,11549981 ! mating behavior GO:0007617 7 6 0,000 0,03009908 0,1153159 ! neuron remodeling GO:0016322 15 6 0,000 0,03009908 0,11513256 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03009908 0,11494981 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03009908 0,11476764 ! equilibrioception GO:0050957 14 6 0,000 0,03009908 0,11458605 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03009908 0,11440503 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03009908 0,11422458 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03009908 0,1140447 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03009908 0,11386538 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03009908 0,11368663 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03009908 0,11350844 ! toxin metabolic process GO:0009404 11 6 0,000 0,03009908 0,1133308 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03009908 0,11315372 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03009908 0,1129772 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03009908 0,11280122 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03009908 0,11262579 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03009908 0,1124509 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03009908 0,11227656 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03009908 0,11210276 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03009908 0,11192949 ! thymic T cell selection GO:0045061 12 6 0,000 0,03009908 0,11175676 ! protein lipoylation GO:0009249 10 6 0,000 0,03009908 0,11158456 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03009908 0,1114129 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03009908 0,11124175 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03009908 0,11107114 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03009908 0,11090104 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03009908 0,11073147 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03009908 0,11056242 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03009908 0,11039388 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03009908 0,11022585 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03009908 0,11005833 ! hyperosmotic response GO:0006972 9 6 0,000 0,03009908 0,10989132 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03009908 0,10972482 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03009908 0,10955882 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03009908 0,10939333 ! urea metabolic process GO:0019627 7 6 0,000 0,03009908 0,10922833 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03009908 0,10906383 ! neutrophil activation GO:0042119 8 6 0,000 0,03009908 0,10889982 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03009908 0,10873631 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03009908 0,10857329 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03009908 0,10841075 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03009908 0,1082487 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03009908 0,10808714 ! neuron apoptosis GO:0051402 9 6 0,000 0,03009908 0,10792605 ! nucleoside salvage GO:0043174 9 6 0,000 0,03009908 0,10776545 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03009908 0,10760532 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03009908 0,10744567 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03009908 0,10728649 ! male sex determination GO:0030238 15 6 0,000 0,03009908 0,10712778 ! carnitine transport GO:0015879 10 6 0,000 0,03009908 0,10696955 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03009908 0,10681177 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03009908 0,10665447 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03009908 0,10649762 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03009908 0,10634124 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03009908 0,10618531 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03009908 0,10602984 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03009908 0,10587483 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03009908 0,10572027 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03009908 0,10556615 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03009908 0,10541249 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03009908 0,10525928 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03009908 0,10510651 ! neural nucleus development GO:0048857 14 6 0,000 0,03009908 0,10495418 ! response to UV-C GO:0010225 11 6 0,000 0,03009908 0,10480229 ! astrocyte development GO:0014002 15 6 0,000 0,03009908 0,10465084 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03009908 0,10449983 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03009908 0,10434925 ! interaction with symbiont GO:0051702 13 6 0,000 0,03009908 0,10419911 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03009908 0,1040494 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03009908 0,10390012 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03009908 0,10375126 ! response to copper ion GO:0046688 10 6 0,000 0,03009908 0,10360284 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03009908 0,10345483 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03009908 0,10330725 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03009908 0,10316009 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03009908 0,10301335 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03009908 0,10286702 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03009908 0,10272111 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03009908 0,10257561 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03009908 0,10243053 ! hair follicle maturation GO:0048820 7 6 0,000 0,03009908 0,10228585 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03009908 0,10214158 ! Schwann cell development GO:0014044 15 6 0,000 0,03009908 0,10199772 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03009908 0,10185426 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03009908 0,10171121 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03009908 0,10156856 ! subpallium development GO:0021544 10 6 0,000 0,03009908 0,10142631 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03009908 0,10128445 ! histone ubiquitination GO:0016574 8 6 0,000 0,03009908 0,10114299 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03009908 0,10100193 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03009908 0,10086126 ! G2 phase GO:0051319 16 6 0,000 0,03009908 0,10072098 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03009908 0,10058109 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03009908 0,10044158 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03009908 0,10030247 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03009908 0,10016374 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03009908 0,10002539 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03009908 0,09988742 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03009908 0,09974984 ! receptor internalization GO:0031623 10 6 0,000 0,03009908 0,09961263 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03009908 0,0994758 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03009908 0,09933934 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03009908 0,09920326 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03009908 0,09906755 ! protein deubiquitination GO:0016579 14 6 0,000 0,03009908 0,09893222 ! protein destabilization GO:0031648 9 6 0,000 0,03009908 0,09879725 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03009908 0,09866265 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03009908 0,09852841 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03009908 0,09839454 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03009908 0,09826103 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03009908 0,09812789 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03009908 0,0979951 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03009908 0,09786268 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03009908 0,09773061 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03009908 0,0975989 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03009908 0,09746754 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03009908 0,09733654 ! catecholamine transport GO:0051937 9 6 0,000 0,03009908 0,09720588 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03009908 0,09707558 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03009908 0,09694563 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03009908 0,09681602 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03009908 0,09668676 ! maternal placenta development GO:0001893 12 6 0,000 0,03009908 0,09655784 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03009908 0,09642927 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03009908 0,09630104 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03009908 0,09617315 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03009908 0,0960456 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03009908 0,09591839 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03009908 0,09579151 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03088312 0,09815692 ! cell recognition GO:0008037 85 54 1,000 0,03088312 0,09802743 ! glucose catabolic process GO:0006007 82 55 1,000 0,03194364 0,10126006 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03301836 0,10452918 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03301836 0,10439183 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03301836 0,10425483 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,03410713 0,10755146 ! muscle fiber development GO:0048747 112 57 1,000 0,03410713 0,10741069 ! tRNA transcription GO:0009304 14 7 0,000 0,03502734 0,11016441 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03502734 0,1100206 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03502734 0,10987715 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03502734 0,10973408 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03502734 0,10959139 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03502734 0,10944906 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03502734 0,1093071 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03502734 0,10916551 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03502734 0,10902429 ! prostate gland development GO:0030850 13 7 0,000 0,03502734 0,10888343 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03502734 0,10874294 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03502734 0,1086028 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03502734 0,10846303 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03502734 0,10832362 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03502734 0,10818456 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03502734 0,10804587 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03502734 0,10790752 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03502734 0,10776953 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03502734 0,1076319 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03502734 0,10749461 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03502734 0,10735768 ! glycolipid transport GO:0046836 10 7 0,000 0,03502734 0,10722109 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03502734 0,10708485 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03502734 0,10694895 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03502734 0,1068134 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03502734 0,1066782 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03502734 0,10654333 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03502734 0,10640881 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03502734 0,10627462 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03502734 0,10614078 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03502734 0,10600727 ! mRNA stabilization GO:0048255 18 7 0,000 0,03502734 0,10587409 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03502734 0,10574125 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03502734 0,10560874 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03502734 0,10547657 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03502734 0,10534472 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03502734 0,1052132 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03502734 0,10508202 ! lipoprotein transport GO:0042953 14 7 0,000 0,03502734 0,10495115 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03502734 0,10482062 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03502734 0,10469041 ! rhythmic behavior GO:0007622 15 7 0,000 0,03502734 0,10456052 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03502734 0,10443095 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03502734 0,1043017 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03502734 0,10417278 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03502734 0,10404417 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03502734 0,10391588 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03502734 0,1037879 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03502734 0,10366024 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03502734 0,10353289 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03502734 0,10340586 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03502734 0,10327914 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03502734 0,10315272 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03502734 0,10302662 ! spinal cord patterning GO:0021511 13 7 0,000 0,03502734 0,10290083 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03502734 0,10277534 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03502734 0,10265015 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03502734 0,10252528 ! adrenal gland development GO:0030325 17 7 0,000 0,03502734 0,1024007 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03502734 0,10227643 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03502734 0,10215246 ! ovulation GO:0030728 9 7 0,000 0,03502734 0,10202878 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03502734 0,10190541 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03502734 0,10178234 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,03502734 0,10165956 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03502734 0,10153708 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03502734 0,10141489 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03502734 0,101293 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03502734 0,1011714 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03502734 0,10105009 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03502734 0,10092907 ! galactose metabolic process GO:0006012 13 7 0,000 0,03502734 0,10080834 ! vesicle fusion GO:0006906 17 7 0,000 0,03502734 0,1006879 ! response to dietary excess GO:0002021 8 7 0,000 0,03502734 0,10056775 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03502734 0,10044789 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03502734 0,1003283 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03502734 0,10020901 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03502734 0,10009 ! organ growth GO:0035265 15 7 0,000 0,03502734 0,09997126 ! purine salvage GO:0043101 10 7 0,000 0,03502734 0,09985282 ! nucleoside transport GO:0015858 8 7 0,000 0,03502734 0,09973465 ! parturition GO:0007567 14 7 0,000 0,03502734 0,09961676 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03502734 0,09949915 ! rRNA modification GO:0000154 14 7 0,000 0,03502734 0,09938181 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03502734 0,09926475 ! spindle checkpoint GO:0031577 15 7 0,000 0,03502734 0,09914797 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03502734 0,09903146 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03502734 0,09891523 ! macrophage differentiation GO:0030225 11 7 0,000 0,03502734 0,09879927 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03502734 0,09868358 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03502734 0,09856816 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03502734 0,09845301 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03502734 0,09833813 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03502734 0,09822352 ! fibrinolysis GO:0042730 10 7 0,000 0,03502734 0,09810917 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03502734 0,09799509 ! eating behavior GO:0042755 7 7 0,000 0,03502734 0,09788127 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03502734 0,09776772 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03502734 0,09765443 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03502734 0,09754141 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03502734 0,09742864 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03502734 0,09731614 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03502734 0,09720389 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03502734 0,09709191 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03502734 0,09698018 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03502734 0,09686871 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03502734 0,09675749 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03502734 0,09664653 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03502734 0,09653583 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03502734 0,09642537 ! regulation of meiosis GO:0040020 12 7 0,000 0,03502734 0,09631517 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03502734 0,09620522 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03502734 0,09609553 GO:0002714|positive regulation of B cell mediated immunity, ! oxygen homeostasis GO:0032364 12 7 0,000 0,03502734 0,09598608 ! transcription termination GO:0006353 13 7 0,000 0,03502734 0,09587688 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03502734 0,09576793 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03502734 0,09565922 ! anaphase GO:0051322 17 7 0,000 0,03502734 0,09555077 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03502734 0,09544256 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03502734 0,09533459 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03502734 0,09522687 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03502734 0,09511939 ! diuresis GO:0030146 12 7 0,000 0,03502734 0,09501215 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03502734 0,09490515 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03502734 0,0947984 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03502734 0,09469188 ! antibiotic transport GO:0042891 9 7 0,000 0,03502734 0,09458561 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03502734 0,09447957 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03502734 0,09437377 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03502734 0,09426821 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03502734 0,09416288 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03502734 0,09405779 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03502734 0,09395293 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03502734 0,0938483 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03502734 0,09374391 ! lymph node development GO:0048535 10 7 0,000 0,03502734 0,09363975 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03502734 0,09353582 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03502734 0,09343212 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03502734 0,09332866 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03502734 0,09322542 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03502734 0,0931224 ! adult feeding behavior GO:0008343 9 7 0,000 0,03502734 0,09301962 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03502734 0,09291706 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03502734 0,09281473 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03502734 0,09271262 ! muscle adaptation GO:0043500 14 7 0,000 0,03502734 0,09261074 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03502734 0,09250908 ! retina homeostasis GO:0001895 12 7 0,000 0,03502734 0,09240765 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03502734 0,09230644 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03502734 0,09220544 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03502734 0,09210467 ! protein prenylation GO:0018342 18 7 0,000 0,03502734 0,09200412 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03502734 0,09190379 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03502734 0,09180368 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03502734 0,09170378 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03632614 0,09500074 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,03632614 0,09489759 ! DNA catabolic process GO:0006308 86 59 1,000 0,03632614 0,09479467 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03632614 0,09469196 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,03745603 0,09753162 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,03745603 0,09742618 ! camera-type eye development GO:0043010 116 60 1,000 0,03745603 0,09732097 ! kidney development GO:0001822 122 60 1,000 0,03745603 0,09721598 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,03859931 0,10007536 ! ear development GO:0043583 103 62 1,000 0,0397558 0,10296282 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,0397558 0,1028521 ! gonad development GO:0008406 98 62 1,000 0,0397558 0,10274163 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03993072 0,10308295 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03993072 0,10297247 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,03993072 0,10286222 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03993072 0,10275221 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03993072 0,10264243 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03993072 0,10253288 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03993072 0,10242357 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03993072 0,1023145 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03993072 0,10220565 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03993072 0,10209704 ! meiotic prophase I GO:0007128 13 8 0,000 0,03993072 0,10198865 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03993072 0,1018805 ! oligopeptide transport GO:0006857 15 8 0,000 0,03993072 0,10177258 ! UTP metabolic process GO:0046051 8 8 0,000 0,03993072 0,10166488 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03993072 0,10155741 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03993072 0,10145017 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03993072 0,10134316 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03993072 0,10123637 ! succinate metabolic process GO:0006105 14 8 0,000 0,03993072 0,1011298 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03993072 0,10102346 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03993072 0,10091734 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03993072 0,10081145 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03993072 0,10070578 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03993072 0,10060033 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03993072 0,1004951 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03993072 0,10039009 ! reflex GO:0060004 16 8 0,000 0,03993072 0,10028529 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03993072 0,10018072 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03993072 0,10007637 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03993072 0,09997223 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03993072 0,09986831 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03993072 0,0997646 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03993072 0,09966111 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03993072 0,09955784 ! pigment granule organization GO:0048753 16 8 0,000 0,03993072 0,09945477 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03993072 0,09935193 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03993072 0,09924929 ! histidine metabolic process GO:0006547 16 8 0,000 0,03993072 0,09914686 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03993072 0,09904465 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03993072 0,09894265 ! glycine catabolic process GO:0006546 13 8 0,000 0,03993072 0,09884086 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03993072 0,09873927 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03993072 0,0986379 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03993072 0,09853673 ! melanin metabolic process GO:0006582 15 8 0,000 0,03993072 0,09843577 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03993072 0,09833502 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03993072 0,09823447 ! macrophage activation GO:0042116 12 8 0,000 0,03993072 0,09813413 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03993072 0,09803399 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03993072 0,09793406 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03993072 0,09783433 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03993072 0,0977348 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03993072 0,09763548 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03993072 0,09753636 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03993072 0,09743744 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03993072 0,09733872 ! osteoblast development GO:0002076 16 8 0,000 0,03993072 0,09724019 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03993072 0,09714187 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03993072 0,09704375 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03993072 0,09694582 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03993072 0,0968481 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03993072 0,09675057 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03993072 0,09665323 ! response to UV-B GO:0010224 16 8 0,000 0,03993072 0,09655609 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03993072 0,09645915 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03993072 0,0963624 ! intermediate filament organization GO:0045109 12 8 0,000 0,03993072 0,09626584 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03993072 0,09616948 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03993072 0,09607331 ! cellular extravasation GO:0045123 12 8 0,000 0,03993072 0,09597733 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03993072 0,09588155 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03993072 0,09578595 ! response to antibiotic GO:0046677 11 8 0,000 0,03993072 0,09569055 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03993072 0,09559534 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03993072 0,09550031 ! DNA topological change GO:0006265 12 8 0,000 0,03993072 0,09540547 ! response to tropane GO:0014073 15 8 0,000 0,03993072 0,09531083 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03993072 0,09521636 ! melanosome transport GO:0032402 13 8 0,000 0,03993072 0,09512209 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03993072 0,095028 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03993072 0,0949341 ! mast cell activation GO:0045576 14 8 0,000 0,03993072 0,09484039 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03993072 0,09474686 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03993072 0,09465351 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03993072 0,09456035 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03993072 0,09446737 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03993072 0,09437457 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03993072 0,09428195 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03993072 0,09418952 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03993072 0,09409727 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03993072 0,0940052 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03993072 0,09391331 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03993072 0,09382159 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03993072 0,09373006 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03993072 0,09363871 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03993072 0,09354753 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03993072 0,09345653 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03993072 0,09336571 ! hormone catabolic process GO:0042447 17 8 0,000 0,03993072 0,09327506 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03993072 0,09318459 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03993072 0,09309429 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03993072 0,09300417 ! ATP catabolic process GO:0006200 11 8 0,000 0,03993072 0,09291423 ! blastocyst growth GO:0001832 19 8 0,000 0,03993072 0,09282446 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03993072 0,09273486 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03993072 0,09264543 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03993072 0,09255618 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03993072 0,0924671 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03993072 0,09237818 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03993072 0,09228944 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03993072 0,09220088 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03993072 0,09211248 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03993072 0,09202425 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03993072 0,09193618 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03993072 0,09184829 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03993072 0,09176057 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03993072 0,09167301 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03993072 0,09158562 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03993072 0,09149839 ! regulation of mitosis GO:0007088 105 63 1,000 0,04092535 0,09368828 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04092535 0,09359922 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,04092535 0,09351033 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,04210778 0,0961208 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,04330295 0,09875536 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,04330295 0,09866184 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,04330295 0,0985685 ! actin filament organization GO:0007015 148 66 1,000 0,0445107 0,10122187 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,0445107 0,10112629 ! extracellular matrix organization GO:0030198 133 66 1,000 0,0445107 0,10103089 ! developmental maturation GO:0021700 116 66 1,000 0,0445107 0,10093567 ! cell projection assembly GO:0030031 120 66 1,000 0,0445107 0,10084062 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04480935 0,10142172 ! axon extension GO:0048675 15 9 0,000 0,04480935 0,1013264 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04480935 0,10123126 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04480935 0,10113629 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04480935 0,10104151 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04480935 0,1009469 ! associative learning GO:0008306 20 9 0,000 0,04480935 0,10085247 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04480935 0,10075822 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04480935 0,10066414 ! phosphate transport GO:0006817 19 9 0,000 0,04480935 0,10057023 ! reproductive behavior GO:0019098 19 9 0,000 0,04480935 0,10047651 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04480935 0,10038295 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04480935 0,10028957 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04480935 0,10019637 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04480935 0,10010333 ! GTP metabolic process GO:0046039 9 9 0,000 0,04480935 0,10001047 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04480935 0,09991779 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04480935 0,09982527 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04480935 0,09973292 ! artery development GO:0060840 24 9 0,000 0,04480935 0,09964075 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04480935 0,09954874 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04480935 0,09945691 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04480935 0,09936524 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04480935 0,09927375 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04480935 0,09918242 ! chemosensory behavior GO:0007635 20 9 0,000 0,04480935 0,09909126 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04480935 0,09900027 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04480935 0,09890944 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04480935 0,09881878 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04480935 0,09872829 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04480935 0,09863796 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04480935 0,0985478 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04480935 0,0984578 ! protein targeting to ER GO:0045047 22 9 0,000 0,04480935 0,09836797 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04480935 0,0982783 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04480935 0,09818879 ! T cell selection GO:0045058 23 9 0,000 0,04480935 0,09809945 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,04480935 0,09801026 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04480935 0,09792124 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04480935 0,09783239 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04480935 0,09774369 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04480935 0,09765515 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04480935 0,09756678 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04480935 0,09747856 ! mannose metabolic process GO:0006013 13 9 0,000 0,04480935 0,09739051 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04480935 0,09730261 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04480935 0,09721487 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04480935 0,09712729 ! receptor clustering GO:0043113 18 9 0,000 0,04480935 0,09703987 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04480935 0,0969526 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04480935 0,09686549 ! ruffle organization GO:0031529 15 9 0,000 0,04480935 0,09677854 ! retinol metabolic process GO:0042572 18 9 0,000 0,04480935 0,09669174 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04480935 0,0966051 ! behavioral fear response GO:0001662 22 9 0,000 0,04480935 0,09651861 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04480935 0,09643228 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04480935 0,0963461 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04480935 0,09626008 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04480935 0,09617421 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04480935 0,09608849 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04480935 0,09600293 ! segment specification GO:0007379 13 9 0,000 0,04480935 0,09591752 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04480935 0,09583226 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04480935 0,09574715 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04480935 0,09566219 ! response to amine stimulus GO:0014075 13 9 0,000 0,04480935 0,09557738 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04480935 0,09549273 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04480935 0,09540822 ! erythrocyte development GO:0048821 15 9 0,000 0,04480935 0,09532386 ! gas homeostasis GO:0033483 16 9 0,000 0,04480935 0,09523966 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04480935 0,0951556 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04480935 0,09507168 ! renal water homeostasis GO:0003091 14 9 0,000 0,04480935 0,09498792 ! postreplication repair GO:0006301 22 9 0,000 0,04480935 0,0949043 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04480935 0,09482084 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04480935 0,09473751 ! icosanoid secretion GO:0032309 15 9 0,000 0,04480935 0,09465434 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04480935 0,09457131 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04480935 0,09448842 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,04480935 0,09440568 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04480935 0,09432309 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04480935 0,09424064 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04480935 0,09415833 ! sterol catabolic process GO:0016127 11 9 0,000 0,04480935 0,09407617 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04480935 0,09399415 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04480935 0,09391227 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04480935 0,09383054 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04480935 0,09374895 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04480935 0,0936675 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04480935 0,09358619 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04480935 0,09350502 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04480935 0,09342399 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04480935 0,09334311 ! purine base metabolic process GO:0006144 21 9 0,000 0,04480935 0,09326236 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04480935 0,09318175 ! pigment granule transport GO:0051904 17 9 0,000 0,04480935 0,09310129 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04480935 0,09302096 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04480935 0,09294077 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04480935 0,09286072 ! mitochondrion localization GO:0051646 15 9 0,000 0,04480935 0,0927808 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,04573086 0,09460744 ! activation of MAPK activity GO:0000187 115 67 1,000 0,04573086 0,09452617 ! hexose catabolic process GO:0019320 104 67 1,000 0,04573086 0,09444503 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,04573086 0,09436403 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,04696329 0,09682406 ! negative regulation of cell size GO:0045792 134 69 1,000 0,04820783 0,09930482 ! urogenital system development GO:0001655 137 69 1,000 0,04820783 0,09921987 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,04820783 0,09913507 ! appendage morphogenesis GO:0035107 135 70 1,000 0,04946432 0,10163207 GO:0035108|limb morphogenesis, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04966335 0,10195393 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04966335 0,10186702 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04966335 0,10178025 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04966335 0,10169362 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04966335 0,10160715 ! synapsis GO:0007129 13 10 0,000 0,04966335 0,10152082 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04966335 0,10143464 ! N-glycan processing GO:0006491 20 10 0,000 0,04966335 0,10134861 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04966335 0,10126272 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04966335 0,10117698 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04966335 0,10109138 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04966335 0,10100592 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04966335 0,10092062 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04966335 0,10083545 ! androgen metabolic process GO:0008209 17 10 0,000 0,04966335 0,10075043 ! phospholipid efflux GO:0033700 16 10 0,000 0,04966335 0,10066555 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04966335 0,10058082 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04966335 0,10049622 ! lung alveolus development GO:0048286 26 10 0,000 0,04966335 0,10041177 ! pathogenesis GO:0009405 13 10 0,000 0,04966335 0,10032746 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04966335 0,1002433 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04966335 0,10015927 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04966335 0,10007538 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04966335 0,09999164 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04966335 0,09990803 ! endoderm development GO:0007492 16 10 0,000 0,04966335 0,09982457 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04966335 0,09974124 ! arginine catabolic process GO:0006527 13 10 0,000 0,04966335 0,09965806 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04966335 0,09957501 ! proline metabolic process GO:0006560 13 10 0,000 0,04966335 0,0994921 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04966335 0,09940933 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04966335 0,09932669 ! V(D)J recombination GO:0033151 28 10 0,000 0,04966335 0,09924419 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04966335 0,09916183 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04966335 0,09907961 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04966335 0,09899752 ! B cell proliferation GO:0042100 18 10 0,000 0,04966335 0,09891557 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04966335 0,09883375 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04966335 0,09875207 ! multicellular organism growth GO:0035264 18 10 0,000 0,04966335 0,09867053 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04966335 0,09858912 ! epithelial cell development GO:0002064 20 10 0,000 0,04966335 0,09850784 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04966335 0,0984267 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04966335 0,09834569 ! macroautophagy GO:0016236 17 10 0,000 0,04966335 0,09826481 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04966335 0,09818407 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04966335 0,09810346 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04966335 0,09802298 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04966335 0,09794263 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04966335 0,09786242 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04966335 0,09778233 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04966335 0,09770238 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04966335 0,09762256 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04966335 0,09754286 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04966335 0,0974633 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04966335 0,09738387 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04966335 0,09730457 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04966335 0,09722539 ! response to dsRNA GO:0043331 20 10 0,000 0,04966335 0,09714635 ! DNA ligation GO:0006266 19 10 0,000 0,04966335 0,09706743 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04966335 0,09698864 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04966335 0,09690998 ! melanosome localization GO:0032400 16 10 0,000 0,04966335 0,09683145 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04966335 0,09675304 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04966335 0,09667476 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04966335 0,09659661 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04966335 0,09651859 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04966335 0,09644069 ! mRNA cleavage GO:0006379 17 10 0,000 0,04966335 0,09636291 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04966335 0,09628526 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04966335 0,09620774 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04966335 0,09613034 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04966335 0,09605306 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04966335 0,09597591 ! salivary gland development GO:0007431 27 10 0,000 0,04966335 0,09589888 ! prophase GO:0051324 15 10 0,000 0,04966335 0,09582198 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04966335 0,0957452 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04966335 0,09566854 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04966335 0,09559201 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04966335 0,09551559 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04966335 0,0954393 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04966335 0,09536314 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04966335 0,09528709 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04966335 0,09521116 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04966335 0,09513536 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04966335 0,09505967 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04966335 0,09498411 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 0,000 0,04966335 0,09490866 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04966335 0,09483334 ! blastocyst formation GO:0001825 17 10 0,000 0,04966335 0,09475814 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04966335 0,09468305 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04966335 0,09460808 ! activation of innate immune response GO:0002218 12 10 0,000 0,04966335 0,09453324 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04966335 0,09445851 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04966335 0,09438389 ! response to nicotine GO:0035094 20 10 0,000 0,04966335 0,0943094 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04966335 0,09423502 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04966335 0,09416076 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04966335 0,09408662 ! localization within membrane GO:0051668 20 10 0,000 0,04966335 0,0940126 ! amine catabolic process GO:0009310 117 71 1,000 0,05073262 0,09596122 ! reproductive structure development GO:0048608 113 71 1,000 0,05073262 0,09588584 ! appendage development GO:0048736 136 71 1,000 0,05073262 0,09581058 GO:0060173|limb development, ! carbohydrate transport GO:0008643 110 72 1,000 0,05201257 0,09815077 ! regulation of blood pressure GO:0008217 125 73 1,000 0,05330402 0,10050899 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05449284 0,10267014 ! respiratory burst GO:0045730 17 11 0,000 0,05449284 0,1025898 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05449284 0,10250959 ! neuron fate specification GO:0048665 17 11 0,000 0,05449284 0,1024295 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05449284 0,10234954 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05449284 0,10226971 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05449284 0,10219 ! thyroid gland development GO:0030878 26 11 0,000 0,05449284 0,10211041 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05449284 0,10203095 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05449284 0,10195161 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05449284 0,10187239 ! response to pain GO:0048265 24 11 0,000 0,05449284 0,1017933 ! T cell proliferation GO:0042098 26 11 0,000 0,05449284 0,10171433 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05449284 0,10163548 ! bone resorption GO:0045453 16 11 0,000 0,05449284 0,10155675 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,05449284 0,10147815 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05449284 0,10139966 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05449284 0,1013213 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05449284 0,10124306 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05449284 0,10116494 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05449284 0,10108694 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05449284 0,10100906 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05449284 0,10093131 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05449284 0,10085367 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05449284 0,10077615 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,05449284 0,10069875 ! UV protection GO:0009650 19 11 0,000 0,05449284 0,10062146 ! adult heart development GO:0007512 14 11 0,000 0,05449284 0,1005443 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05449284 0,10046725 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05449284 0,10039033 ! temperature homeostasis GO:0001659 17 11 0,000 0,05449284 0,10031352 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05449284 0,10023682 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05449284 0,10016025 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05449284 0,10008379 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05449284 0,10000745 ! regulation of organ growth GO:0046620 13 11 0,000 0,05449284 0,09993122 ! pigment granule localization GO:0051875 20 11 0,000 0,05449284 0,09985512 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05449284 0,09977912 ! vasoconstriction GO:0042310 18 11 0,000 0,05449284 0,09970324 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05449284 0,09962748 ! embryonic axis specification GO:0000578 18 11 0,000 0,05449284 0,09955183 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05449284 0,0994763 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05449284 0,09940088 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05449284 0,09932558 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05449284 0,09925039 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05449284 0,09917531 ! zymogen activation GO:0031638 15 11 0,000 0,05449284 0,09910035 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05449284 0,0990255 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05449284 0,09895077 ! nucleosome positioning GO:0016584 15 11 0,000 0,05449284 0,09887614 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05449284 0,09880163 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05449284 0,09872723 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05449284 0,09865295 ! acid secretion GO:0046717 18 11 0,000 0,05449284 0,09857877 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05449284 0,09850471 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05449284 0,09843076 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05449284 0,09835691 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05449284 0,09828318 ! oocyte differentiation GO:0009994 18 11 0,000 0,05449284 0,09820956 ! thymus development GO:0048538 27 11 0,000 0,05449284 0,09813605 ! cholesterol efflux GO:0033344 19 11 0,000 0,05449284 0,09806265 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05449284 0,09798936 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05449284 0,09791618 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05449284 0,09784311 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05449284 0,09777015 ! embryonic gut development GO:0048566 15 11 0,000 0,05449284 0,09769729 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05449284 0,09762455 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05449284 0,09755191 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05449284 0,09747938 ! defense response to fungus GO:0050832 13 11 0,000 0,05449284 0,09740696 ! developmental induction GO:0031128 19 11 0,000 0,05449284 0,09733464 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05449284 0,09726244 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05449284 0,09719034 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05449284 0,09711835 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05449284 0,09704646 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05449284 0,09697468 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05449284 0,09690301 ! nucleus localization GO:0051647 19 11 0,000 0,05449284 0,09683144 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05449284 0,09675998 ! neurotransmitter transport GO:0006836 123 74 1,000 0,05460683 0,09689088 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,05460683 0,09681948 ! organelle localization GO:0051640 136 74 1,000 0,05460683 0,09674819 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,05592085 0,09900336 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05592085 0,09893056 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,05592085 0,09885787 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,05724593 0,10112608 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,05724593 0,10105188 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05929795 0,1045974 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05929795 0,10452077 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05929795 0,10444426 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05929795 0,10436785 ! virus-host interaction GO:0019048 29 12 0,000 0,05929795 0,10429156 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,05929795 0,10421538 ! cartilage condensation GO:0001502 20 12 0,000 0,05929795 0,10413931 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05929795 0,10406335 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05929795 0,10398751 ! protein complex disassembly GO:0043241 27 12 0,000 0,05929795 0,10391177 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05929795 0,10383614 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05929795 0,10376062 ! hippocampus development GO:0021766 26 12 0,000 0,05929795 0,10368522 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05929795 0,10360992 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05929795 0,10353473 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05929795 0,10345965 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05929795 0,10338468 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05929795 0,10330982 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05929795 0,10323506 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05929795 0,10316042 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05929795 0,10308588 ! drug transport GO:0015893 16 12 0,000 0,05929795 0,10301145 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05929795 0,10293713 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05929795 0,10286291 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05929795 0,1027888 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05929795 0,1027148 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05929795 0,1026409 ! forebrain cell migration GO:0021885 21 12 0,000 0,05929795 0,10256712 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05929795 0,10249343 ! entry into host cell GO:0030260 32 12 0,000 0,05929795 0,10241985 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05929795 0,10234638 ! monoamine transport GO:0015844 18 12 0,000 0,05929795 0,10227302 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05929795 0,10219975 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05929795 0,1021266 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05929795 0,10205355 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05929795 0,1019806 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05929795 0,10190776 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05929795 0,10183502 ! protein homotetramerization GO:0051289 21 12 0,000 0,05929795 0,10176238 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05929795 0,10168985 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05929795 0,10161742 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05929795 0,10154509 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05929795 0,10147287 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05929795 0,10140075 ! cranial nerve development GO:0021545 20 12 0,000 0,05929795 0,10132873 ! fucose catabolic process GO:0019317 22 12 0,000 0,05929795 0,10125682 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 26 12 0,000 0,05929795 0,10118501 ! histone methylation GO:0016571 26 12 0,000 0,05929795 0,10111329 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05929795 0,10104168 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05929795 0,10097018 ! gland morphogenesis GO:0022612 29 12 0,000 0,05929795 0,10089877 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05929795 0,10082746 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05929795 0,10075626 ! T cell homeostasis GO:0043029 25 12 0,000 0,05929795 0,10068515 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05929795 0,10061414 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05929795 0,10054324 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05929795 0,10047243 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05929795 0,10040173 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05929795 0,10033112 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05929795 0,10026062 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05929795 0,10019021 ! response to cold GO:0009409 17 12 0,000 0,05929795 0,1001199 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05929795 0,10004969 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05929795 0,09997958 ! blood coagulation GO:0007596 146 78 1,000 0,05992871 0,10097232 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,05992871 0,10090166 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,05992871 0,1008311 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,05992871 0,10076064 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,06128612 0,10297095 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,06128612 0,10289909 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,06128612 0,10282734 ! protein import into nucleus GO:0006606 158 80 1,000 0,06265402 0,10504918 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,06403227 0,10728526 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,06403227 0,1072106 ! nuclear import GO:0051170 161 81 1,000 0,06403227 0,10713605 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,06403227 0,1070616 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06407879 0,10706498 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06407879 0,10699068 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06407879 0,10691649 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06407879 0,1068424 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06407879 0,1067684 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06407879 0,10669452 ! lipid localization GO:0010876 28 13 0,000 0,06407879 0,10662073 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06407879 0,10654705 ! organelle fusion GO:0048284 32 13 0,000 0,06407879 0,10647346 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06407879 0,10639998 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06407879 0,1063266 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06407879 0,10625333 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06407879 0,10618015 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06407879 0,10610707 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06407879 0,1060341 ! methionine metabolic process GO:0006555 27 13 0,000 0,06407879 0,10596122 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06407879 0,10588845 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06407879 0,10581577 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06407879 0,10574319 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06407879 0,10567072 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06407879 0,10559834 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06407879 0,10552606 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06407879 0,10545388 ! exocrine system development GO:0035272 32 13 0,000 0,06407879 0,1053818 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06407879 0,10530982 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06407879 0,10523794 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06407879 0,10516615 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06407879 0,10509446 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06407879 0,10502287 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06407879 0,10495138 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06407879 0,10487998 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06407879 0,10480869 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06407879 0,10473748 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06407879 0,10466638 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06407879 0,10459537 ! ribosome assembly GO:0042255 17 13 0,000 0,06407879 0,10452446 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,06407879 0,10445364 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06407879 0,10438292 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06407879 0,1043123 ! chromatin silencing GO:0006342 26 13 0,000 0,06407879 0,10424177 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06407879 0,10417134 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06407879 0,104101 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06407879 0,10403075 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06407879 0,1039606 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06407879 0,10389055 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06407879 0,10382059 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06407879 0,10375072 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06407879 0,10368095 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06407879 0,10361127 ! embryonic placenta development GO:0001892 23 13 0,000 0,06407879 0,10354169 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06407879 0,1034722 ! insulin secretion GO:0030073 23 13 0,000 0,06407879 0,1034028 ! actin filament polymerization GO:0030041 24 13 0,000 0,06407879 0,1033335 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06407879 0,10326428 ! acrosome reaction GO:0007340 18 13 0,000 0,06407879 0,10319516 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,06542073 0,10528581 ! hemostasis GO:0007599 158 84 1,000 0,06822775 0,10972992 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,06822775 0,10965662 ! negative regulation of transport GO:0051051 153 84 1,000 0,06822775 0,10958342 ! negative regulation of growth GO:0045926 155 84 1,000 0,06822775 0,10951032 ! rRNA transcription GO:0009303 25 14 0,000 0,0688355 0,11041214 ! lactation GO:0007595 26 14 0,000 0,0688355 0,11033859 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0688355 0,11026512 ! reproductive cellular process GO:0048610 20 14 0,000 0,0688355 0,11019176 ! tRNA modification GO:0006400 20 14 0,000 0,0688355 0,11011849 ! regulation of S phase GO:0033261 23 14 0,000 0,0688355 0,11004533 ! water transport GO:0006833 21 14 0,000 0,0688355 0,10997226 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0688355 0,10989928 ! non-recombinational repair GO:0000726 25 14 0,000 0,0688355 0,1098264 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0688355 0,10975362 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0688355 0,10968094 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0688355 0,10960835 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0688355 0,10953586 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0688355 0,10946346 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0688355 0,10939116 ! palate development GO:0060021 31 14 0,000 0,0688355 0,10931895 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0688355 0,10924684 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0688355 0,10917483 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0688355 0,10910291 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0688355 0,10903108 ! arginine metabolic process GO:0006525 17 14 0,000 0,0688355 0,10895935 ! regulation of heart rate GO:0002027 24 14 0,000 0,0688355 0,10888772 ! organic alcohol transport GO:0015850 29 14 0,000 0,0688355 0,10881617 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0688355 0,10874473 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0688355 0,10867337 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0688355 0,10860211 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0688355 0,10853094 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0688355 0,10845987 ! L-amino acid transport GO:0015807 30 14 0,000 0,0688355 0,10838889 ! bone mineralization GO:0030282 17 14 0,000 0,0688355 0,108318 ! stem cell development GO:0048864 43 14 0,000 0,0688355 0,1082472 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0688355 0,1081765 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0688355 0,10810589 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0688355 0,10803537 ! cerebellum development GO:0021549 21 14 0,000 0,0688355 0,10796494 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0688355 0,1078946 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0688355 0,10782436 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0688355 0,10775421 ! cofactor transport GO:0051181 26 14 0,000 0,0688355 0,10768415 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0688355 0,10761418 ! intestinal absorption GO:0050892 25 14 0,000 0,0688355 0,1075443 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0688355 0,10747451 ! oxygen transport GO:0015671 21 14 0,000 0,0688355 0,10740481 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0688355 0,1073352 ! male genitalia development GO:0030539 24 14 0,000 0,0688355 0,10726568 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0688355 0,10719626 ! regulation of axon extension GO:0030516 37 14 0,000 0,0688355 0,10712692 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0688355 0,10705767 ! response to unfolded protein GO:0006986 131 85 1,000 0,06964603 0,10824829 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,06964603 0,1081784 GO:0002696|positive regulation of leukocyte activation, ! alcohol catabolic process GO:0046164 130 86 1,000 0,07107398 0,11032516 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,07251146 0,11248393 ! protein localization in nucleus GO:0034504 176 87 1,000 0,07251146 0,11241145 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07356819 0,11397622 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07356819 0,11390288 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07356819 0,11382963 ! superoxide anion generation GO:0042554 20 15 0,000 0,07356819 0,11375647 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07356819 0,11368341 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07356819 0,11361044 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07356819 0,11353757 ! copper ion transport GO:0006825 20 15 0,000 0,07356819 0,11346479 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07356819 0,1133921 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07356819 0,11331951 ! sulfate transport GO:0008272 23 15 0,000 0,07356819 0,113247 ! response to cAMP GO:0051591 22 15 0,000 0,07356819 0,1131746 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07356819 0,11310228 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07356819 0,11303006 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07356819 0,11295793 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07356819 0,11288589 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07356819 0,11281394 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07356819 0,11274208 ! pituitary gland development GO:0021983 29 15 0,000 0,07356819 0,11267032 ! vesicle coating GO:0006901 33 15 0,000 0,07356819 0,11259864 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07356819 0,11252706 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07356819 0,11245557 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07356819 0,11238417 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07356819 0,11231286 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07356819 0,11224164 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07356819 0,11217051 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07356819 0,11209947 ! histone deacetylation GO:0016575 20 15 0,000 0,07356819 0,11202852 ! tissue regeneration GO:0042246 26 15 0,000 0,07356819 0,11195767 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07356819 0,1118869 ! water homeostasis GO:0030104 27 15 0,000 0,07356819 0,11181622 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07356819 0,11174562 ! muscle maintenance GO:0046716 26 15 0,000 0,07356819 0,11167512 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07356819 0,11160471 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07356819 0,11153438 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07356819 0,11146415 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07356819 0,111394 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07356819 0,11132394 ! cell killing GO:0001906 29 15 0,000 0,07356819 0,11125397 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07356819 0,11118409 ! detection of bacterium GO:0016045 18 15 0,000 0,07356819 0,11111429 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07356819 0,11104459 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07356819 0,11097496 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07356819 0,11090543 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07356819 0,11083599 ! peptide hormone processing GO:0016486 23 15 0,000 0,07356819 0,11076663 ! gland development GO:0048732 206 88 1,000 0,07395835 0,11128442 ! regulation of neurological system process GO:0031644 148 88 1,000 0,07395835 0,11121486 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,0754145 0,11333373 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,0768798 0,11546368 ! sex differentiation GO:0007548 145 90 1,000 0,0768798 0,11539165 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07827698 0,11741548 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07827698 0,11734232 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07827698 0,11726925 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07827698 0,11719628 ! bone remodeling GO:0046849 27 16 0,000 0,07827698 0,1171234 ! filopodium assembly GO:0046847 32 16 0,000 0,07827698 0,1170506 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07827698 0,1169779 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07827698 0,11690529 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07827698 0,11683277 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07827698 0,11676034 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07827698 0,11668799 ! startle response GO:0001964 28 16 0,000 0,07827698 0,11661574 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07827698 0,11654358 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07827698 0,1164715 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07827698 0,11639952 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07827698 0,11632762 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07827698 0,11625582 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07827698 0,1161841 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07827698 0,11611247 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07827698 0,11604093 ! response to osmotic stress GO:0006970 25 16 0,000 0,07827698 0,11596947 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,07827698 0,11589811 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,07827698 0,11582683 ! fructose metabolic process GO:0006000 25 16 0,000 0,07827698 0,11575564 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07827698 0,11568454 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07827698 0,11561352 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07827698 0,11554259 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07827698 0,11547175 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07827698 0,11540099 ! axon cargo transport GO:0008088 43 16 0,000 0,07827698 0,11533033 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07827698 0,11525974 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07827698 0,11518925 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07827698 0,11511884 ! DNA replication initiation GO:0006270 27 16 0,000 0,07827698 0,11504852 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07827698 0,11497828 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07827698 0,11490813 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07827698 0,11483806 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07827698 0,11476808 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,07827698 0,11469819 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07827698 0,11462838 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07827698 0,11455865 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07827698 0,11448901 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07827698 0,11441946 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07827698 0,11434998 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07827698 0,1142806 ! defense response to virus GO:0051607 37 16 0,000 0,07827698 0,11421129 ! response to protein stimulus GO:0051789 149 91 1,000 0,07835412 0,11425455 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,07835412 0,11418534 ! vitamin metabolic process GO:0006766 139 92 1,000 0,07983731 0,11627638 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,08132927 0,11837763 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08132927 0,11830605 ! regulation of T cell activation GO:0050863 158 94 1,000 0,08282985 0,12041609 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,082962 0,12053537 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,082962 0,12046262 ! metencephalon development GO:0022037 30 17 0,000 0,082962 0,12038997 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,082962 0,1203174 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,082962 0,12024492 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,082962 0,12017253 ! signal complex assembly GO:0007172 41 17 0,000 0,082962 0,12010022 ! endothelial cell migration GO:0043542 28 17 0,000 0,082962 0,120028 ! inositol metabolic process GO:0006020 28 17 0,000 0,082962 0,11995587 ! gene silencing by RNA GO:0031047 36 17 0,000 0,082962 0,11988382 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,082962 0,11981187 ! glial cell development GO:0021782 27 17 0,000 0,082962 0,11973999 ! limbic system development GO:0021761 36 17 0,000 0,082962 0,11966821 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,082962 0,11959651 ! adult walking behavior GO:0007628 33 17 0,000 0,082962 0,11952489 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,082962 0,11945336 ! heart looping GO:0001947 30 17 0,000 0,082962 0,11938192 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,082962 0,11931056 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,082962 0,11923929 ! myoblast differentiation GO:0045445 45 17 0,000 0,082962 0,1191681 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,082962 0,119097 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,082962 0,11902598 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,082962 0,11895505 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,082962 0,1188842 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,082962 0,11881343 ! NAD metabolic process GO:0019674 29 17 0,000 0,082962 0,11874275 ! membrane budding GO:0006900 37 17 0,000 0,082962 0,11867216 ! DNA integration GO:0015074 29 17 0,000 0,082962 0,11860164 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,082962 0,11853122 ! regulation of protein binding GO:0043393 33 17 0,000 0,082962 0,11846087 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,082962 0,11839061 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,082962 0,11832043 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,082962 0,11825034 ! genitalia development GO:0048806 30 17 0,000 0,082962 0,11818032 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,082962 0,1181104 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,082962 0,11804055 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,082962 0,11797078 ! steroid catabolic process GO:0006706 31 17 0,000 0,082962 0,1179011 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,082962 0,1178315 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,082962 0,11776199 ! gas transport GO:0015669 25 17 0,000 0,082962 0,11769255 ! organic cation transport GO:0015695 31 17 0,000 0,082962 0,1176232 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,082962 0,11755393 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,082962 0,11748474 ! microspike assembly GO:0030035 36 17 0,000 0,082962 0,11741563 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,082962 0,1173466 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,082962 0,11727765 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,08433895 0,11915414 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08762335 0,12372171 ! neuron maturation GO:0042551 42 18 0,000 0,08762335 0,12364914 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08762335 0,12357666 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,08762335 0,12350427 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08762335 0,12343196 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08762335 0,12335974 ! memory GO:0007613 31 18 0,000 0,08762335 0,1232876 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08762335 0,12321554 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08762335 0,12314357 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08762335 0,12307168 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08762335 0,12299988 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08762335 0,12292816 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08762335 0,12285652 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08762335 0,12278497 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08762335 0,1227135 ! response to retinoic acid GO:0032526 26 18 0,000 0,08762335 0,12264211 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08762335 0,12257081 ! response to fungus GO:0009620 21 18 0,000 0,08762335 0,12249959 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08762335 0,12242845 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08762335 0,12235739 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08762335 0,12228642 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08762335 0,12221553 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08762335 0,12214472 ! vitamin transport GO:0051180 27 18 0,000 0,08762335 0,122074 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08762335 0,12200335 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08762335 0,12193279 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08762335 0,12186231 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08762335 0,12179191 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08762335 0,12172159 ! nerve development GO:0021675 28 18 0,000 0,08762335 0,12165135 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08762335 0,12158119 ! response to virus GO:0009615 160 98 1,000 0,08891603 0,12330373 ! interphase GO:0051325 213 98 1,000 0,08891603 0,12323271 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,08891603 0,12316176 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,09045793 0,12522541 GO:0060538|skeletal muscle organ development, ! protein secretion GO:0009306 39 19 0,000 0,09226117 0,12764829 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09226117 0,12757493 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09226117 0,12750165 ! skin development GO:0043588 36 19 0,000 0,09226117 0,12742846 ! lipid phosphorylation GO:0046834 35 19 0,000 0,09226117 0,12735535 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09226117 0,12728233 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09226117 0,12720938 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09226117 0,12713653 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09226117 0,12706375 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09226117 0,12699106 ! cerebral cortex development GO:0021987 36 19 0,000 0,09226117 0,12691845 ! pigmentation during development GO:0048066 41 19 0,000 0,09226117 0,12684593 ! response to vitamin A GO:0033189 27 19 0,000 0,09226117 0,12677349 ! heme metabolic process GO:0042168 36 19 0,000 0,09226117 0,12670113 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09226117 0,12662885 ! protein export from nucleus GO:0006611 36 19 0,000 0,09226117 0,12655666 ! heart process GO:0003015 30 19 0,000 0,09226117 0,12648454 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09226117 0,12641251 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09226117 0,12634057 ! visual learning GO:0008542 36 19 0,000 0,09226117 0,1262687 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09226117 0,12619692 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09226117 0,12612521 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09226117 0,12605359 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09226117 0,12598205 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09226117 0,12591059 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09226117 0,12583922 ! cilium assembly GO:0042384 37 19 0,000 0,09226117 0,12576792 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09226117 0,1256967 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09687556 0,13190866 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09687556 0,13183405 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09687556 0,13175953 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09687556 0,13168509 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,09687556 0,13161073 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,09687556 0,13153646 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09687556 0,13146227 ! response to vitamin GO:0033273 31 20 0,000 0,09687556 0,13138817 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09687556 0,13131415 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,09687556 0,13124021 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09687556 0,13116635 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09687556 0,13109258 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09687556 0,13101889 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09687556 0,13094529 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,09687556 0,13087176 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,09687556 0,13079832 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09687556 0,13072496 ! body fluid secretion GO:0007589 31 20 0,000 0,09687556 0,13065169 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09687556 0,13057849 ! peptide secretion GO:0002790 35 20 0,000 0,09687556 0,13050538 ! stem cell differentiation GO:0048863 53 20 0,000 0,09687556 0,13043235 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09687556 0,1303594 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,09687556 0,13028653 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09687556 0,13021375 ! sensory perception of pain GO:0019233 30 20 0,000 0,09687556 0,13014104 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09687556 0,13006842 ! diencephalon development GO:0021536 34 20 0,000 0,09687556 0,12999588 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09687556 0,12992342 GO:0006626|protein targeting to mitochondrion, ! peptidyl-serine modification GO:0018209 43 20 0,000 0,09687556 0,12985104 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09687556 0,12977874 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09687556 0,12970652 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09687556 0,12963438 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,09687556 0,12956232 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09687556 0,12949034 ! regulation of glucose import GO:0046324 29 20 0,000 0,09687556 0,12941844 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09687556 0,12934662 ! actin filament-based movement GO:0030048 43 20 0,000 0,09687556 0,12927488 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09687556 0,12920322 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09687556 0,12913164 ! negative regulation of translation GO:0017148 29 20 0,000 0,09687556 0,12906014 ! regulation of cell killing GO:0031341 42 21 0,000 0,10146665 0,1351017 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10146665 0,13502698 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10146665 0,13495233 ! hormone secretion GO:0046879 38 21 0,000 0,10146665 0,13487777 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10146665 0,1348033 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10146665 0,1347289 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10146665 0,13465459 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10146665 0,13458036 ! axis specification GO:0009798 38 21 0,000 0,10146665 0,13450621 ! ovarian follicle development GO:0001541 35 21 0,000 0,10146665 0,13443214 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10146665 0,13435816 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10146665 0,13428425 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10146665 0,13421043 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10146665 0,13413669 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10146665 0,13406303 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10146665 0,13398945 ! cytolysis GO:0019835 24 21 0,000 0,10146665 0,13391595 ! vasodilation GO:0042311 39 21 0,000 0,10146665 0,13384253 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10146665 0,13376919 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10146665 0,13369593 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10146665 0,13362275 ! oogenesis GO:0048477 36 21 0,000 0,10146665 0,13354966 ! collagen fibril organization GO:0030199 59 21 0,000 0,10146665 0,13347664 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10146665 0,1334037 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10146665 0,13333084 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10146665 0,13325806 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10146665 0,13318536 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10146665 0,13311274 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10146665 0,1330402 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10146665 0,13296774 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10146665 0,13289536 ! collagen catabolic process GO:0030574 28 21 0,000 0,10146665 0,13282305 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10146665 0,13275083 ! gut development GO:0048565 39 21 0,000 0,10146665 0,13267868 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10603456 0,1385764 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10603456 0,13850116 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10603456 0,13842601 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10603456 0,13835095 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10603456 0,13827596 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10603456 0,13820105 ! regeneration GO:0031099 41 22 0,000 0,10603456 0,13812623 ! keratinization GO:0031424 28 22 0,000 0,10603456 0,13805149 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10603456 0,13797682 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10603456 0,13790224 ! sensory perception of taste GO:0050909 28 22 0,000 0,10603456 0,13782774 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10603456 0,13775332 ! vacuolar transport GO:0007034 36 22 0,000 0,10603456 0,13767898 ! lysosome organization GO:0007040 41 22 0,000 0,10603456 0,13760472 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10603456 0,13753054 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10603456 0,13745644 ! fucose metabolic process GO:0006004 39 22 0,000 0,10603456 0,13738242 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10603456 0,13730847 ! ureteric bud development GO:0001657 43 22 0,000 0,10603456 0,13723461 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10603456 0,13716083 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10603456 0,13708713 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10603456 0,1370135 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,10603456 0,13693996 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10603456 0,13686649 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10603456 0,13679311 ! sarcomere organization GO:0045214 30 22 0,000 0,10603456 0,1367198 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,10603456 0,13664657 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10603456 0,13657342 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,10603456 0,13650035 ! protein stabilization GO:0050821 39 22 0,000 0,10603456 0,13642735 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11057939 0,14219883 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11057939 0,14212287 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11057939 0,14204699 ! viral genome replication GO:0019079 41 23 0,000 0,11057939 0,14197119 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11057939 0,14189547 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11057939 0,14181984 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11057939 0,14174428 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11057939 0,1416688 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11057939 0,14159341 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11057939 0,14151809 ! visual behavior GO:0007632 42 23 0,000 0,11057939 0,14144286 ! response to ethanol GO:0045471 46 23 0,000 0,11057939 0,1413677 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11057939 0,14129262 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11057939 0,14121763 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11057939 0,14114271 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11057939 0,14106787 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11057939 0,14099312 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11057939 0,14091844 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11057939 0,14084384 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11057939 0,14076932 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11057939 0,14069488 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11057939 0,14062051 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11057939 0,14054623 ! fatty acid transport GO:0015908 44 23 0,000 0,11057939 0,14047202 ! platelet activation GO:0030168 37 23 0,000 0,11057939 0,14039789 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11057939 0,14032385 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11057939 0,14024987 ! hormone transport GO:0009914 40 23 0,000 0,11057939 0,14017598 ! cell-cell recognition GO:0009988 25 23 0,000 0,11057939 0,14010216 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11057939 0,14002843 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11057939 0,13995477 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11057939 0,13988118 GO:0006099|tricarboxylic acid cycle, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,11510127 0,14552477 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11510127 0,14544834 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11510127 0,14537199 ! vesicle docking GO:0048278 47 24 0,000 0,11510127 0,14529572 ! spinal cord development GO:0021510 47 24 0,000 0,11510127 0,14521953 ! vacuole organization GO:0007033 43 24 0,000 0,11510127 0,14514342 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11510127 0,14506739 ! digestive system process GO:0022600 39 24 0,000 0,11510127 0,14499144 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11510127 0,14491557 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11510127 0,14483977 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11510127 0,14476406 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11510127 0,14468843 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,11510127 0,14461287 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,11510127 0,14453739 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11510127 0,144462 ! membrane depolarization GO:0051899 39 24 0,000 0,11510127 0,14438668 ! pallium development GO:0021543 49 24 0,000 0,11510127 0,14431144 ! pentose metabolic process GO:0019321 35 24 0,000 0,11510127 0,14423627 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,11510127 0,14416119 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,11510127 0,14408618 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11510127 0,14401126 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11510127 0,14393641 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11510127 0,14386163 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11510127 0,14378694 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11510127 0,14371232 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11510127 0,14363778 ! regulation of amine transport GO:0051952 40 24 0,000 0,11510127 0,14356332 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,1196003 0,14909758 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,1196003 0,14902037 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,1196003 0,14894323 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,1196003 0,14886618 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,1196003 0,14878921 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,1196003 0,14871231 ! receptor metabolic process GO:0043112 46 25 0,000 0,1196003 0,1486355 ! chromosome condensation GO:0030261 45 25 0,000 0,1196003 0,14855876 ! osteoblast differentiation GO:0001649 60 25 0,000 0,1196003 0,14848211 ! neural crest cell development GO:0014032 54 25 0,000 0,1196003 0,14840553 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,1196003 0,14832903 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,1196003 0,14825262 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,1196003 0,14817628 ! interaction with host GO:0051701 62 25 0,000 0,1196003 0,14810001 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,1196003 0,14802383 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,1196003 0,14794773 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,1196003 0,1478717 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,1196003 0,14779575 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,1196003 0,14771988 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,1196003 0,14764409 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,1196003 0,14756837 ! telomere organization GO:0032200 43 25 0,000 0,1196003 0,14749274 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,1196003 0,14741718 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,1196003 0,14734169 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12407661 0,15277806 ! embryonic pattern specification GO:0009880 44 26 0,000 0,12407661 0,15269991 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12407661 0,15262185 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12407661 0,15254386 ! initiation of viral infection GO:0019059 57 26 0,000 0,12407661 0,15246595 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12407661 0,15238812 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12407661 0,15231037 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,12407661 0,1522327 ! molting cycle process GO:0022404 50 26 0,000 0,12407661 0,15215511 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,12407661 0,1520776 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12407661 0,15200017 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,12407661 0,15192282 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12407661 0,15184554 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12407661 0,15176834 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,12407661 0,15169123 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,12407661 0,15161419 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,12407661 0,15153722 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12407661 0,15146034 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12407661 0,15138354 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12407661 0,15130681 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,12407661 0,15123016 ! blastocyst development GO:0001824 49 26 0,000 0,12407661 0,15115359 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12407661 0,15107709 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12407661 0,15100067 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,12407661 0,15092433 ! neuron fate commitment GO:0048663 48 27 0,000 0,12853031 0,15626273 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,12853031 0,1561838 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,12853031 0,15610496 ! iron ion transport GO:0006826 59 27 0,000 0,12853031 0,1560262 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,12853031 0,15594752 ! protein amino acid acylation GO:0043543 55 27 0,000 0,12853031 0,15586892 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12853031 0,15579039 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12853031 0,15571195 ! fat cell differentiation GO:0045444 50 27 0,000 0,12853031 0,15563359 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12853031 0,1555553 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,12853031 0,15547709 ! autophagy GO:0006914 41 27 0,000 0,12853031 0,15539896 ! response to toxin GO:0009636 47 27 0,000 0,12853031 0,15532091 ! primary neural tube formation GO:0014020 51 27 0,000 0,12853031 0,15524294 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12853031 0,15516504 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12853031 0,15508723 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12853031 0,15500949 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12853031 0,15493183 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12853031 0,15485425 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,12853031 0,15477674 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13296152 0,16003272 ! circadian rhythm GO:0007623 50 28 0,000 0,13296152 0,1599527 ! dendrite development GO:0016358 59 28 0,000 0,13296152 0,15987277 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13296152 0,15979291 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,13296152 0,15971313 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13296152 0,15963344 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13296152 0,15955382 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,13296152 0,15947428 ! synaptogenesis GO:0007416 42 28 0,000 0,13296152 0,15939482 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,13296152 0,15931544 ! lipid oxidation GO:0034440 43 28 0,000 0,13296152 0,15923614 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13296152 0,15915692 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,13296152 0,15907777 ! translational initiation GO:0006413 65 29 0,000 0,13737033 0,16427088 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,13737033 0,16418928 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,13737033 0,16410775 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13737033 0,16402631 ! catechol metabolic process GO:0009712 54 29 0,000 0,13737033 0,16394495 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13737033 0,16386367 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,13737033 0,16378247 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,13737033 0,16370135 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,13737033 0,16362031 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,13737033 0,16353935 ! cell fate determination GO:0001709 60 29 0,000 0,13737033 0,16345847 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13737033 0,16337767 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,13737033 0,16329695 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,13737033 0,16321631 ! tissue homeostasis GO:0001894 48 29 0,000 0,13737033 0,16313574 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,14175688 0,16826198 ! zinc ion transport GO:0006829 45 30 0,000 0,14175688 0,16817902 ! membrane docking GO:0022406 61 30 0,000 0,14175688 0,16809613 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14175688 0,16801332 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14175688 0,1679306 ! acute-phase response GO:0006953 49 30 0,000 0,14175688 0,16784795 ! myofibril assembly GO:0030239 47 30 0,000 0,14175688 0,16776539 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14175688 0,16768291 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14175688 0,16760051 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,14175688 0,16751819 ! phospholipid transport GO:0015914 51 30 0,000 0,14175688 0,16743596 ! cofactor catabolic process GO:0051187 51 30 0,000 0,14175688 0,1673538 ! eye morphogenesis GO:0048592 60 30 0,000 0,14175688 0,16727172 ! regulation of B cell activation GO:0050864 50 30 0,000 0,14175688 0,16718973 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14612126 0,17225269 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14612126 0,17216834 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14612126 0,17208407 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14612126 0,17199988 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,14612126 0,17191577 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,14612126 0,17183174 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14612126 0,1717478 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,14612126 0,17166394 ! ovulation cycle process GO:0022602 49 31 0,000 0,14612126 0,17158016 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,14612126 0,17149646 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14612126 0,17141285 ! peptide transport GO:0015833 55 31 0,000 0,14612126 0,17132931 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,14612126 0,17124586 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14612126 0,17116249 ! mesoderm formation GO:0001707 69 31 0,000 0,14612126 0,1710792 ! natural killer cell activation GO:0030101 45 31 0,000 0,14612126 0,17099599 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14612126 0,17091286 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14612126 0,17082981 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,14612126 0,17074684 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,14612126 0,17066396 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15046359 0,17565037 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15046359 0,17556518 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15046359 0,17548008 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15046359 0,17539506 ! cholesterol transport GO:0030301 56 32 0,000 0,15046359 0,17531012 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15046359 0,17522527 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15046359 0,1751405 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15046359 0,1750558 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15046359 0,1749712 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,15046359 0,17488667 ! muscle cell development GO:0055001 49 32 0,000 0,15046359 0,17480222 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15046359 0,17471786 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15046359 0,17463358 ! ovulation cycle GO:0042698 51 32 0,000 0,15046359 0,17454938 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15046359 0,17446526 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15046359 0,17438122 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15046359 0,17429726 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,15046359 0,17421338 ! gene silencing GO:0016458 65 32 0,000 0,15046359 0,17412958 ! post-embryonic development GO:0009791 69 33 0,000 0,15478399 0,1790434 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15478399 0,17895736 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15478399 0,17887141 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15478399 0,17878554 ! formation of primary germ layer GO:0001704 72 33 0,000 0,15478399 0,17869975 ! cell fate specification GO:0001708 52 33 0,000 0,15478399 0,17861404 ! sterol transport GO:0015918 57 33 0,000 0,15478399 0,17852841 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,15478399 0,17844287 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 0,000 0,15478399 0,17835741 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,15478399 0,17827203 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15478399 0,17818673 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,15908255 0,18304764 ! glial cell differentiation GO:0010001 63 34 0,000 0,15908255 0,18296014 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,15908255 0,18287273 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,15908255 0,1827854 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,15908255 0,18269815 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,15908255 0,18261098 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,15908255 0,1825239 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,15908255 0,1824369 ! spermatid development GO:0007286 63 34 0,000 0,15908255 0,18234999 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,15908255 0,18226315 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,15908255 0,1821764 ! placenta development GO:0001890 53 34 0,000 0,15908255 0,18208973 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,15908255 0,18200315 ! regulation of muscle development GO:0048634 70 35 0,000 0,1633594 0,18680737 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,1633594 0,18671863 ! negative regulation of secretion GO:0051048 63 35 0,000 0,1633594 0,18662997 ! odontogenesis GO:0042476 66 35 0,000 0,1633594 0,18654139 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,1633594 0,1864529 ! female gonad development GO:0008585 58 35 0,000 0,1633594 0,18636449 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,1633594 0,18627617 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,1633594 0,18618793 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,1633594 0,18609977 ! cytokine production GO:0001816 59 35 0,000 0,1633594 0,1860117 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,1633594 0,18592371 ! neural tube formation GO:0001841 67 35 0,000 0,1633594 0,1858358 ! vesicle localization GO:0051648 64 35 0,000 0,1633594 0,18574797 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,16761464 0,19049637 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,16761464 0,19040643 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,16761464 0,19031657 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,16761464 0,1902268 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,16761464 0,19013711 ! positive regulation of cell development GO:0010720 80 36 0,000 0,16761464 0,19004751 ! regulation of proteolysis GO:0030162 72 36 0,000 0,16761464 0,18995799 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,16761464 0,18986856 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,16761464 0,18977921 ! aerobic respiration GO:0009060 55 36 0,000 0,16761464 0,18968994 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,16761464 0,18960076 ! embryonic organ development GO:0048568 57 36 0,000 0,16761464 0,18951166 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17184837 0,19420722 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17184837 0,19411605 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,17184837 0,19402495 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17184837 0,19393395 ! organic anion transport GO:0015711 68 37 0,000 0,17184837 0,19384303 ! tissue remodeling GO:0048771 76 37 0,000 0,17184837 0,19375219 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,17184837 0,19366144 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17184837 0,19357078 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,17184837 0,1934802 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17184837 0,1933897 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,17184837 0,19329929 ! glycogen metabolic process GO:0005977 61 37 0,000 0,17184837 0,19320896 ! pigment metabolic process GO:0042440 80 37 0,000 0,17184837 0,19311872 ! spermatid differentiation GO:0048515 66 37 0,000 0,17184837 0,19302856 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,17606071 0,19766779 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,17606071 0,19757559 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,17606071 0,19748348 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,17606071 0,19739146 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,17606071 0,19729952 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,17606071 0,19720767 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,17606071 0,1971159 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,17606071 0,19702422 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,17606071 0,19693262 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,17606071 0,19684111 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,17606071 0,19674968 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,17606071 0,19665834 ! glucan metabolic process GO:0044042 62 38 0,000 0,17606071 0,19656709 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,18025176 0,20115294 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18025176 0,20105969 ! segmentation GO:0035282 67 39 0,000 0,18025176 0,20096652 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18025176 0,20087343 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18025176 0,20078044 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18025176 0,20068753 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18025176 0,2005947 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18442164 0,2051403 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18442164 0,2050455 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18442164 0,20495079 ! feeding behavior GO:0007631 59 40 0,000 0,18442164 0,20485617 ! negative regulation of binding GO:0051100 72 40 0,000 0,18442164 0,20476163 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18442164 0,20466719 ! mesenchymal cell development GO:0014031 87 40 0,000 0,18442164 0,20457283 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18442164 0,20447855 ! maintenance of protein location GO:0045185 91 40 0,000 0,18442164 0,20438437 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,18857044 0,20888604 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,18857044 0,20878991 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,18857044 0,20869387 ! gliogenesis GO:0042063 88 41 0,000 0,18857044 0,20859792 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,18857044 0,20850206 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,18857044 0,20840628 ! female gamete generation GO:0007292 61 41 0,000 0,18857044 0,2083106 ! polyol metabolic process GO:0019751 66 41 0,000 0,18857044 0,208215 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,19269827 0,21267525 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,19269827 0,21257774 ! regulation of tube size GO:0035150 71 42 0,000 0,19269827 0,21248031 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19269827 0,21238298 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19269827 0,21228573 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,19269827 0,21218858 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,19269827 0,21209151 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19269827 0,21199453 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,19680524 0,21641381 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,19680524 0,21631495 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,19680524 0,21621617 ! striated muscle contraction GO:0006941 77 43 0,000 0,19680524 0,21611749 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,20089146 0,22050404 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,20089146 0,22040349 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,20089146 0,22030303 ! developmental growth GO:0048589 82 44 0,000 0,20089146 0,22020266 ! maintenance of location in cell GO:0051651 97 44 0,000 0,20089146 0,22010239 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,20495702 0,22445452 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,20495702 0,22435241 ! leukocyte migration GO:0050900 68 45 0,000 0,20495702 0,22425038 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,20495702 0,22414845 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,20495702 0,22404661 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,20495702 0,22394486 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,20495702 0,22384321 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,20495702 0,22374165 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,20900203 0,22805392 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,20900203 0,22795054 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,20900203 0,22784725 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,20900203 0,22774406 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,20900203 0,22764096 ! positive regulation of defense response GO:0031349 76 47 0,000 0,2130266 0,23191945 ! endosome transport GO:0016197 108 47 0,000 0,2130266 0,23181456 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,2130266 0,23170976 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,2130266 0,23160506 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,2130266 0,23150045 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,2130266 0,23139593 ! JNK cascade GO:0007254 91 47 0,000 0,2130266 0,23129151 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,2130266 0,23118718 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,21703082 0,23542658 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,21703082 0,23532048 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,21703082 0,23521448 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,21703082 0,23510857 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,21703082 0,23500277 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2210148 0,239209 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,2210148 0,23910144 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,2210148 0,23899398 ! regulation of ion transport GO:0043269 77 49 0,000 0,2210148 0,23888661 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,2210148 0,23877934 ! peptide metabolic process GO:0006518 76 49 0,000 0,2210148 0,23867217 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2210148 0,2385651 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2210148 0,23845812 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,22497864 0,242626 ! neuromuscular process GO:0050905 99 50 0,000 0,22497864 0,24251729 ! regulation of ossification GO:0030278 117 50 0,000 0,22497864 0,24240869 ! inner ear development GO:0048839 79 50 0,000 0,22497864 0,24230018 ! histone modification GO:0016570 91 50 0,000 0,22497864 0,24219177 ! positive regulation of binding GO:0051099 78 51 0,000 0,22892244 0,24632709 ! viral infectious cycle GO:0019058 99 51 0,000 0,22892244 0,24621698 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,22892244 0,24610696 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,22892244 0,24599704 ! excretion GO:0007588 83 51 0,000 0,22892244 0,24588722 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,22892244 0,2457775 ! chromatin remodeling GO:0006338 109 51 0,000 0,22892244 0,24566788 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,22892244 0,24555835 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,22892244 0,24544892 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,22892244 0,24533959 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2328463 0,24943375 ! membrane fusion GO:0006944 110 52 0,000 0,2328463 0,24932274 ! positive regulation of growth GO:0045927 90 52 0,000 0,2328463 0,24921183 ! covalent chromatin modification GO:0016569 101 52 0,000 0,2328463 0,24910102 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2328463 0,24899031 ! amino acid activation GO:0043038 92 52 0,000 0,2328463 0,2488797 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,2328463 0,24876918 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,23675033 0,25282791 ! RNA catabolic process GO:0006401 93 53 0,000 0,23675033 0,25271574 ! regulation of translational initiation GO:0006446 82 53 0,000 0,23675033 0,25260367 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,23675033 0,2524917 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,23675033 0,25237983 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,23675033 0,25226806 ! cell maturation GO:0048469 100 53 0,000 0,23675033 0,25215639 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,23675033 0,25204482 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,24063461 0,25606673 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,24063461 0,25595353 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,24063461 0,25584042 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,24063461 0,25572742 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,24063461 0,25561451 ! chloride transport GO:0006821 90 55 0,000 0,24449926 0,25960513 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,24449926 0,25949061 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,24449926 0,2593762 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,24449926 0,25926189 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,24449926 0,25914767 ! gastrulation GO:0007369 112 55 0,000 0,24449926 0,25903356 ! heart morphogenesis GO:0003007 97 55 0,000 0,24449926 0,25891955 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,24449926 0,25880564 ! RNA elongation GO:0006354 79 55 0,000 0,24449926 0,25869183 ! nuclear export GO:0051168 97 55 0,000 0,24449926 0,25857812 ! regulation of actin filament length GO:0030832 105 56 0,000 0,24834437 0,26252924 ! sensory perception of smell GO:0007608 80 56 0,000 0,24834437 0,26241394 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,24834437 0,26229875 ! proton transport GO:0015992 94 56 0,000 0,24834437 0,26218365 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,25217003 0,26610574 ! lipid modification GO:0030258 97 57 0,000 0,25217003 0,26598908 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,25217003 0,26587252 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,25217003 0,26575607 ! maintenance of location GO:0051235 118 57 0,000 0,25217003 0,26563971 ! hydrogen transport GO:0006818 97 58 0,000 0,25597635 0,26953134 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,25597635 0,26941343 ! regulation of endocytosis GO:0030100 91 58 0,000 0,25597635 0,26929563 ! adult behavior GO:0030534 99 58 0,000 0,25597635 0,26917793 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,25597635 0,26906033 ! positive regulation of secretion GO:0051047 95 59 0,000 0,25976342 0,27292175 ! regulation of cellular component size GO:0032535 109 59 0,000 0,25976342 0,27280262 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,25976342 0,2726836 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,25976342 0,27256468 ! regulation of heart contraction GO:0008016 110 60 0,000 0,26353135 0,27639774 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,26353135 0,27627731 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,26728021 0,28008545 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,26728021 0,27996352 ! mesoderm development GO:0007498 119 61 0,000 0,26728021 0,27984169 ! tRNA processing GO:0008033 89 61 0,000 0,26728021 0,27971996 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,26728021 0,27959835 ! viral reproductive process GO:0022415 126 62 0,000 0,27101012 0,28337695 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,27472117 0,28713255 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,27472117 0,28700787 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,27841344 0,29073904 ! cell redox homeostasis GO:0045454 102 64 0,000 0,27841344 0,2906129 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,27841344 0,29048688 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,27841344 0,29036096 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,28208704 0,29406474 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,28208704 0,29393739 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,28574207 0,29761706 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,2893786 0,3012743 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,2893786 0,30114399 ! lung development GO:0030324 144 67 0,000 0,2893786 0,3010138 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,2893786 0,30088371 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,2893786 0,30075374 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,2893786 0,30062388 ! activation of immune response GO:0002253 105 67 0,000 0,2893786 0,30049413 ! amino acid transport GO:0006865 125 68 0,000 0,29299674 0,30412 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29299674 0,30398885 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,29299674 0,30385782 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,29299674 0,30372691 ! viral reproduction GO:0016032 134 68 0,000 0,29299674 0,3035961 ! regulation of lipase activity GO:0060191 130 68 0,000 0,29299674 0,30346541 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,29299674 0,30333483 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,29659657 0,30692962 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,29659657 0,30679766 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,29659657 0,30666582 ! antigen processing and presentation GO:0019882 104 69 0,000 0,29659657 0,30653409 ! respiratory tube development GO:0030323 150 70 0,000 0,3001782 0,31010251 ! humoral immune response GO:0006959 109 71 0,000 0,30374171 0,31364916 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,30374171 0,31351461 ! regulation of immune effector process GO:0002697 137 71 0,000 0,30374171 0,31338017 ! acute inflammatory response GO:0002526 113 72 0,000 0,30728719 0,31690226 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,30728719 0,31676649 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,30728719 0,31663083 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,30728719 0,31649528 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,30728719 0,31635985 ! respiratory system development GO:0060541 153 72 0,000 0,30728719 0,31622454 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31081473 0,31971794 ! fertilization GO:0009566 90 73 0,000 0,31081473 0,3195813 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,31432443 0,32305194 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,31432443 0,322914 ! exocytosis GO:0006887 133 74 0,000 0,31432443 0,32277618 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,31432443 0,32263847 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,31781637 0,32608366 ! rhythmic process GO:0048511 128 75 0,000 0,31781637 0,32594467 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32129064 0,3293674 ! defense response to bacterium GO:0042742 89 76 0,000 0,32129064 0,32922713 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,32129064 0,32908697 ! regulation of catabolic process GO:0009894 161 76 0,000 0,32129064 0,32894693 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,32474734 0,33234457 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,32474734 0,33220327 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,32474734 0,33206209 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,32474734 0,33192103 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33160834 0,33878967 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,33160834 0,33864587 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,33160834 0,33850219 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,33501283 0,34183243 ! muscle cell differentiation GO:0042692 159 80 0,000 0,33501283 0,34168752 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,33501283 0,34154274 ! inorganic anion transport GO:0015698 138 80 0,000 0,33501283 0,34139808 ! digestion GO:0007586 112 81 0,000 0,33840008 0,3447039 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,33840008 0,34455802 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,3417702 0,34784226 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,3417702 0,34769518 ! response to nutrient GO:0007584 125 82 0,000 0,3417702 0,34754822 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,3417702 0,34740139 ! regulation of lyase activity GO:0051339 160 83 0,000 0,34512326 0,35066155 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,34845935 0,35390173 ! regulation of ligase activity GO:0051340 142 84 0,000 0,34845935 0,3537524 ! nucleosome assembly GO:0006334 122 85 0,000 0,35177856 0,35697141 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,35508096 0,36017066 ! chromatin assembly GO:0031497 124 86 0,000 0,35508096 0,36001888 ! tube morphogenesis GO:0035239 176 86 0,000 0,35508096 0,35986723 ! amine transport GO:0015837 155 86 0,000 0,35508096 0,3597157 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,35836665 0,36289149 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 0,000 0,35836665 0,36273882 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,36163572 0,36589383 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,36163572 0,36574003 ! regulation of DNA binding GO:0051101 155 88 0,000 0,36163572 0,36558636 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36163572 0,36543281 ! cellular defense response GO:0006968 114 89 0,000 0,36488823 0,36856468 ! ossification GO:0001503 188 90 0,000 0,36812428 0,3716773 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,36812428 0,3715214 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,36812428 0,37136562 ! bone development GO:0060348 189 91 0,000 0,37134395 0,37445664 ! sterol metabolic process GO:0016125 152 91 0,000 0,37134395 0,37429976 ! regulation of defense response GO:0031347 149 92 0,000 0,37454732 0,37737054 ! nucleosome organization GO:0034728 138 92 0,000 0,37454732 0,37721258 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,37454732 0,37705475 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,37773447 0,3801042 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,37773447 0,37994529 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,38090549 0,38297476 ! female pregnancy GO:0007565 164 94 0,000 0,38090549 0,38281479 ! forebrain development GO:0030900 188 95 0,000 0,38406045 0,3858244 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,38406045 0,38566337 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,38719944 0,38865326 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,38719944 0,38849118 ! positive regulation of immune response GO:0050778 156 96 0,000 0,38719944 0,38832924 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39032254 0,39129834 ! protein ubiquitination GO:0016567 217 97 0,000 0,39032254 0,39113537 ! hormone metabolic process GO:0042445 157 97 0,000 0,39032254 0,39097253 ! regulation of protein localization GO:0032880 176 97 0,000 0,39032254 0,39080983 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,39342982 0,39375713 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,39652137 0,39668624 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,39652137 0,39652137