pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6222-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycine metabolic process GO:0006544 30 18 5,000 1,246E-10 3,043E-07 ! one-carbon metabolic process GO:0006730 167 88 8,000 2,28E-10 2,785E-07 ! glycine biosynthetic process GO:0006545 7 5 3,000 1,873E-09 1,525E-06 ! serine family amino acid metabolic process GO:0009069 56 34 5,000 8,509E-09 5,197E-06 ! regulation of helicase activity GO:0051095 16 7 3,000 1,302E-08 6,361E-06 ! regulation of DNA metabolic process GO:0051052 188 97 7,000 1,318E-08 5,368E-06 ! serine family amino acid biosynthetic process GO:0009070 19 14 3,000 3,634E-07 1,268E-04 ! positive regulation of helicase activity GO:0051096 12 5 2,000 8,562E-07 2,615E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 8,562E-07 2,324E-04 ! negative regulation of DNA recombination GO:0045910 16 7 2,000 2,977E-06 7,273E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 4,748E-06 1,054E-03 ! regulation of DNA replication GO:0006275 105 56 4,000 5,181E-06 1,055E-03 ! protein sumoylation GO:0016925 17 10 2,000 1,011E-05 1,899E-03 ! synaptic vesicle endocytosis GO:0048488 23 10 2,000 1,011E-05 1,764E-03 ! negative regulation of DNA metabolic process GO:0051053 65 35 3,000 1,767E-05 2,879E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 2,000 1,841E-05 2,811E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 3,026E-05 4,349E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 4,625E-05 6,277E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 4,859E-05 6,247E-03 ! pigmentation GO:0043473 103 46 3,000 5,303E-05 6,478E-03 ! regulation of endothelial cell migration GO:0010594 45 19 2,000 7,925E-05 9,22E-03 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 2,000 7,925E-05 8,801E-03 ! cellular amino acid biosynthetic process GO:0008652 80 52 3,000 8,617E-05 9,153E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 9,293E-05 9,46E-03 ! cellular aldehyde metabolic process GO:0006081 35 22 2,000 1,247E-04 0,01218813 ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,247E-04 0,01171936 ! positive regulation of locomotion GO:0040017 44 22 2,000 1,247E-04 0,01128531 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! somatic diversification of immunoglobulins GO:0016445 55 22 2,000 1,247E-04 0,01088226 ! positive regulation of DNA replication GO:0045740 44 23 2,000 1,43E-04 0,01204369 ! regulation of chemotaxis GO:0050920 45 23 2,000 1,43E-04 0,01164223 ! regulation of DNA recombination GO:0000018 51 23 2,000 1,43E-04 0,01126668 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 2,000 1,629E-04 0,01243318 GO:0016444|somatic cell DNA recombination, ! synaptic vesicle transport GO:0048489 52 24 2,000 1,629E-04 0,01205642 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 1,715E-04 0,0123259 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,845E-04 0,01287552 ! regulation of behavior GO:0050795 48 25 2,000 1,845E-04 0,01251786 ! immunoglobulin production GO:0002377 62 25 2,000 1,845E-04 0,01217954 GO:0002440|production of molecular mediator of immune response, ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 1,946E-04 0,01251295 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,946E-04 0,0121921 ! Notch receptor processing GO:0007220 11 5 1,000 1,946E-04 0,0118873 ! apoptotic cell clearance GO:0043277 23 5 1,000 1,946E-04 0,01159736 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,946E-04 0,01132124 ! virus-infected cell apoptosis GO:0006926 7 5 1,000 1,946E-04 0,01105795 ! G2/M transition checkpoint GO:0031576 8 5 1,000 1,946E-04 0,01080664 GO:0031572|G2/M transition DNA damage checkpoint, ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,946E-04 0,01056649 ! positive regulation of blood coagulation GO:0030194 12 5 1,000 1,946E-04 0,01033678 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 1,946E-04 0,01011685 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 1,946E-04 9,906E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 1,946E-04 9,704E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 2,078E-04 0,01015527 ! regulation of blood coagulation GO:0030193 46 26 2,000 2,078E-04 9,956E-03 ! somatic diversification of immune receptors GO:0002200 63 26 2,000 2,078E-04 9,765E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 2,331E-04 0,01074291 ! regulation of chromosome organization GO:0033044 49 27 2,000 2,331E-04 0,01054397 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,602E-04 0,01155679 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,893E-04 0,01261887 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 2,911E-04 0,01247637 ! negative regulation of platelet activation GO:0010544 9 6 1,000 2,911E-04 0,01226126 GO:0010543|regulation of platelet activation, ! establishment of spindle localization GO:0051293 16 6 1,000 2,911E-04 0,01205344 GO:0051653|spindle localization, ! neural tube patterning GO:0021532 8 6 1,000 2,911E-04 0,01185255 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,911E-04 0,01165825 ! determination of adult lifespan GO:0008340 17 6 1,000 2,911E-04 0,01147021 ! positive regulation of coagulation GO:0050820 13 6 1,000 2,911E-04 0,01128814 ! regulation of coagulation GO:0050818 52 30 2,000 3,204E-04 0,01222843 ! learning or memory GO:0007611 161 76 3,000 3,76E-04 0,01413014 ! neuron adhesion GO:0007158 14 7 1,000 4,063E-04 0,01504099 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,063E-04 0,01481649 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 4,063E-04 0,0145986 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 1,000 4,063E-04 0,01438703 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 4,063E-04 0,0141815 ! B cell lineage commitment GO:0002326 21 7 1,000 4,063E-04 0,01398176 ! negative regulation of focal adhesion formation GO:0051895 21 7 1,000 4,063E-04 0,01378757 ! T cell lineage commitment GO:0002360 16 7 1,000 4,063E-04 0,0135987 ! regulation of lipid transport GO:0032368 14 7 1,000 4,063E-04 0,01341493 ! axonal fasciculation GO:0007413 19 7 1,000 4,063E-04 0,01323607 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 1,000 4,063E-04 0,01306191 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 1,000 4,063E-04 0,01289227 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 4,661E-04 0,01459696 ! DNA damage checkpoint GO:0000077 78 35 2,000 5,081E-04 0,01571209 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 5,402E-04 0,01649676 GO:0016446|somatic hypermutation of immunoglobulin genes, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,402E-04 0,01629309 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,402E-04 0,0160944 ! L-phenylalanine metabolic process GO:0006558 12 8 1,000 5,402E-04 0,01590049 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 1,000 5,402E-04 0,0157112 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 1,000 5,402E-04 0,01552636 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 5,402E-04 0,01534582 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 5,402E-04 0,01516943 ! multicellular organismal aging GO:0010259 20 8 1,000 5,402E-04 0,01499705 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 5,402E-04 0,01482854 ! response to tumor cell GO:0002347 16 8 1,000 5,402E-04 0,01466378 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 5,402E-04 0,01450264 GO:0002688|regulation of leukocyte chemotaxis, ! negative regulation of organic acid transport GO:0032891 13 8 1,000 5,402E-04 0,014345 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 1,000 5,402E-04 0,01419076 ! negative regulation of cell activation GO:0050866 69 37 2,000 5,993E-04 0,01557462 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 6,485E-04 0,01667723 ! meiosis I GO:0007127 74 38 2,000 6,485E-04 0,01650351 ! DNA integrity checkpoint GO:0031570 82 38 2,000 6,485E-04 0,01633337 ! amine biosynthetic process GO:0009309 146 88 3,000 6,557E-04 0,01634571 ! RNA methylation GO:0001510 16 9 1,000 6,925E-04 0,01708944 ! middle ear morphogenesis GO:0042474 14 9 1,000 6,925E-04 0,01691854 ! pentose-phosphate shunt GO:0006098 16 9 1,000 6,925E-04 0,01675103 GO:0006740|NADPH regeneration, ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 6,925E-04 0,01658681 ! regulation of macrophage activation GO:0043030 17 9 1,000 6,925E-04 0,01642577 ! regulation of telomere maintenance GO:0032204 17 9 1,000 6,925E-04 0,01626783 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 7,003E-04 0,01629324 ! learning GO:0007612 82 40 2,000 7,546E-04 0,01739148 ! mismatch repair GO:0006298 58 40 2,000 7,546E-04 0,01722894 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 8,07E-04 0,01825507 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 8,631E-04 0,01934536 ! phagocytosis, engulfment GO:0006911 33 10 1,000 8,631E-04 0,0191695 ! midbrain development GO:0030901 14 10 1,000 8,631E-04 0,0189968 ! detection of calcium ion GO:0005513 24 10 1,000 8,631E-04 0,01882719 ! regulation of fibrinolysis GO:0051917 20 10 1,000 8,631E-04 0,01866057 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 8,631E-04 0,01849688 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 8,631E-04 0,01833604 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 1,000 8,631E-04 0,01817797 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 8,631E-04 0,0180226 ! motor axon guidance GO:0008045 22 10 1,000 8,631E-04 0,01786987 ! T cell differentiation GO:0030217 93 42 2,000 8,711E-04 0,01788365 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 2,000 9,985E-04 0,02032712 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 9,985E-04 0,02015913 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,052E-03 0,02106321 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,052E-03 0,02089197 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,052E-03 0,02072349 ! L-serine metabolic process GO:0006563 21 11 1,000 1,052E-03 0,0205577 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,052E-03 0,02039454 ! substrate-bound cell migration GO:0006929 14 11 1,000 1,052E-03 0,02023395 ! DNA methylation GO:0006306 19 11 1,000 1,052E-03 0,02007588 GO:0006305|DNA alkylation, ! apical protein localization GO:0045176 18 11 1,000 1,052E-03 0,01992025 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,052E-03 0,01976702 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 1,052E-03 0,01961612 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! regulation of organic acid transport GO:0032890 19 11 1,000 1,052E-03 0,01946752 ! biopolymer methylation GO:0043414 91 45 2,000 1,066E-03 0,01958653 ! negative regulation of cell migration GO:0030336 122 46 2,000 1,137E-03 0,02072921 ! positive regulation of blood pressure GO:0045777 18 12 1,000 1,259E-03 0,02277526 ! focal adhesion formation GO:0048041 37 12 1,000 1,259E-03 0,02260779 ! negative regulation of endothelial cell migration GO:0010596 26 12 1,000 1,259E-03 0,02244277 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 1,259E-03 0,02228014 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 1,259E-03 0,02211985 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,259E-03 0,02196185 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,259E-03 0,0218061 GO:0042130|negative regulation of T cell proliferation, ! methylation GO:0032259 97 48 2,000 1,287E-03 0,02214381 ! response to calcium ion GO:0051592 94 49 2,000 1,367E-03 0,0233471 ! detection of stimulus involved in sensory perception GO:0050906 75 49 2,000 1,367E-03 0,02318496 ! activation of caspase activity GO:0006919 95 50 2,000 1,449E-03 0,02441537 ! folic acid and derivative biosynthetic process GO:0009396 25 13 1,000 1,483E-03 0,0248157 ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 1,483E-03 0,02464689 ! endocrine pancreas development GO:0031018 25 13 1,000 1,483E-03 0,02448036 ! plasma membrane organization GO:0007009 27 13 1,000 1,483E-03 0,02431606 ! response to X-ray GO:0010165 28 13 1,000 1,483E-03 0,02415395 ! asymmetric protein localization GO:0008105 24 13 1,000 1,483E-03 0,02399399 ! membrane protein proteolysis GO:0033619 33 13 1,000 1,483E-03 0,02383614 GO:0006509|membrane protein ectodomain proteolysis, ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 1,483E-03 0,02368035 ! spleen development GO:0048536 24 13 1,000 1,483E-03 0,02352658 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,483E-03 0,02337479 ! detection of abiotic stimulus GO:0009582 80 51 2,000 1,535E-03 0,02403401 ! negative regulation of immune system process GO:0002683 101 51 2,000 1,535E-03 0,02388093 ! regulation of neuron apoptosis GO:0043523 117 53 2,000 1,715E-03 0,02652094 ! regulation of cellular pH GO:0030641 27 14 1,000 1,725E-03 0,02650705 ! response to gamma radiation GO:0010332 30 14 1,000 1,725E-03 0,02634138 ! NADP metabolic process GO:0006739 24 14 1,000 1,725E-03 0,02617777 ! regulation of angiogenesis GO:0045765 125 54 2,000 1,81E-03 0,02729896 ! response to UV GO:0009411 120 55 2,000 1,908E-03 0,02860386 ! negative regulation of cell motion GO:0051271 142 55 2,000 1,908E-03 0,02842944 ! pteridine and derivative biosynthetic process GO:0042559 20 15 1,000 1,985E-03 0,02938699 ! response to hexose stimulus GO:0009746 25 15 1,000 1,985E-03 0,02920996 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 1,000 1,985E-03 0,02903505 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,985E-03 0,02886222 ! regulation of exocytosis GO:0017157 26 15 1,000 1,985E-03 0,02869144 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,985E-03 0,02852267 ! positive regulation of caspase activity GO:0043280 108 57 2,000 2,115E-03 0,03021299 GO:0010952|positive regulation of peptidase activity, ! positive regulation of cell migration GO:0030335 137 58 2,000 2,223E-03 0,03157325 ! aging GO:0007568 112 58 2,000 2,223E-03 0,03139075 ! neuron recognition GO:0008038 40 16 1,000 2,262E-03 0,0317552 ! mRNA splice site selection GO:0006376 44 16 1,000 2,262E-03 0,03157374 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 2,262E-03 0,03139434 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,556E-03 0,03527622 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 2,556E-03 0,03507804 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 2,556E-03 0,03488207 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,556E-03 0,03468828 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,556E-03 0,03449663 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 2,556E-03 0,03430709 ! negative regulation of blood coagulation GO:0030195 25 17 1,000 2,556E-03 0,03411962 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,867E-03 0,03806484 ! aromatic compound biosynthetic process GO:0019438 26 18 1,000 2,867E-03 0,03785908 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 2,944E-03 0,03866501 ! positive regulation of cell motion GO:0051272 157 65 2,000 3,076E-03 0,04018887 ! positive regulation of translation GO:0045727 31 19 1,000 3,195E-03 0,04151672 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 3,195E-03 0,04129706 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 3,195E-03 0,0410797 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 3,195E-03 0,04086463 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 3,195E-03 0,04065179 ! neuromuscular junction development GO:0007528 43 19 1,000 3,195E-03 0,04044116 ! response to lipopolysaccharide GO:0032496 34 19 1,000 3,195E-03 0,0402327 ! peptide cross-linking GO:0018149 39 19 1,000 3,195E-03 0,04002638 ! cellular pigmentation GO:0033059 37 19 1,000 3,195E-03 0,03982216 ! folic acid and derivative metabolic process GO:0006760 39 19 1,000 3,195E-03 0,03962002 ! proximal/distal pattern formation GO:0009954 33 19 1,000 3,195E-03 0,03941992 ! chromosome segregation GO:0007059 127 67 2,000 3,352E-03 0,04115123 ! secondary metabolic process GO:0019748 125 67 2,000 3,352E-03 0,04094548 ! detection of external stimulus GO:0009581 102 68 2,000 3,495E-03 0,04248455 ! adaptive immune response GO:0002250 126 68 2,000 3,495E-03 0,04227423 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of angiogenesis GO:0045766 50 20 1,000 3,54E-03 0,04259682 ! forelimb morphogenesis GO:0035136 35 20 1,000 3,54E-03 0,04238802 ! response to alkaloid GO:0043279 38 20 1,000 3,54E-03 0,04218124 ! retinoid metabolic process GO:0001523 34 20 1,000 3,54E-03 0,04197648 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 1,000 3,54E-03 0,0417737 ! response to carbohydrate stimulus GO:0009743 33 20 1,000 3,54E-03 0,04157286 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,54E-03 0,04137395 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 3,54E-03 0,04117693 ! aromatic compound catabolic process GO:0019439 31 20 1,000 3,54E-03 0,04098178 ! negative regulation of T cell activation GO:0050868 41 20 1,000 3,54E-03 0,04078847 ! negative regulation of coagulation GO:0050819 30 20 1,000 3,54E-03 0,04059697 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 3,643E-03 0,04158286 ! negative regulation of kinase activity GO:0033673 145 70 2,000 3,793E-03 0,04310315 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 3,901E-03 0,04411848 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 3,901E-03 0,04391517 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,901E-03 0,04371372 ! cell cycle checkpoint GO:0000075 145 71 2,000 3,948E-03 0,0440402 ! B cell activation GO:0042113 179 72 2,000 4,106E-03 0,04559854 ! pteridine and derivative metabolic process GO:0042558 32 22 1,000 4,278E-03 0,04729448 ! glutamate signaling pathway GO:0007215 48 22 1,000 4,278E-03 0,04708144 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 4,278E-03 0,04687031 ! cellular response to starvation GO:0009267 37 22 1,000 4,278E-03 0,04666107 ! apoptotic nuclear changes GO:0030262 34 22 1,000 4,278E-03 0,04645369 ! cell aging GO:0007569 48 22 1,000 4,278E-03 0,04624814 ! G1 phase GO:0051318 44 22 1,000 4,278E-03 0,04604441 ! detection of chemical stimulus GO:0009593 42 22 1,000 4,278E-03 0,04584246 ! terpenoid metabolic process GO:0006721 40 22 1,000 4,278E-03 0,04564227 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 4,278E-03 0,04544383 ! regulation of caspase activity GO:0043281 136 74 2,000 4,434E-03 0,04689799 ! negative regulation of transferase activity GO:0051348 155 74 2,000 4,434E-03 0,04669584 ! eye development GO:0001654 155 75 2,000 4,604E-03 0,0482766 ! axon guidance GO:0007411 162 75 2,000 4,604E-03 0,04807029 ! gluconeogenesis GO:0006094 38 23 1,000 4,672E-03 0,04857129 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,672E-03 0,04836548 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 4,672E-03 0,0481614 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 4,672E-03 0,04795904 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,672E-03 0,04775838 ! DNA modification GO:0006304 36 23 1,000 4,672E-03 0,04755939 ! negative regulation of cytokine production GO:0001818 41 23 1,000 4,672E-03 0,04736204 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 4,672E-03 0,04716633 ! lymphocyte differentiation GO:0030098 193 76 2,000 4,778E-03 0,04803691 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 4,956E-03 0,04961909 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,082E-03 0,0506765 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 5,082E-03 0,0504705 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 5,082E-03 0,05026616 ! sex determination GO:0007530 48 24 1,000 5,082E-03 0,05006348 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 5,082E-03 0,04986242 ! protein oligomerization GO:0051259 149 79 2,000 5,323E-03 0,05201671 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 5,508E-03 0,0536103 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 5,508E-03 0,05339756 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 5,508E-03 0,05318651 ! phototransduction GO:0007602 37 25 1,000 5,508E-03 0,05297711 ! vasculogenesis GO:0001570 49 25 1,000 5,508E-03 0,05276936 ! negative regulation of DNA replication GO:0008156 45 25 1,000 5,508E-03 0,05256323 ! protein tetramerization GO:0051262 57 25 1,000 5,508E-03 0,0523587 ! meiosis GO:0007126 143 81 2,000 5,706E-03 0,05403205 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 2,000 5,706E-03 0,05382343 ! regulation of peptidase activity GO:0052547 150 82 2,000 5,904E-03 0,05547334 ! meiotic cell cycle GO:0051321 144 82 2,000 5,904E-03 0,0552608 ! myelination GO:0042552 50 26 1,000 5,95E-03 0,05547794 ! pyruvate metabolic process GO:0006090 43 26 1,000 5,95E-03 0,055267 ! negative regulation of cell development GO:0010721 83 26 1,000 5,95E-03 0,05505766 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 5,95E-03 0,05484989 GO:0045840|positive regulation of mitosis, ! response to drug GO:0042493 149 83 2,000 6,106E-03 0,05607434 ! response to oxygen levels GO:0070482 183 83 2,000 6,106E-03 0,05586433 ! response to metal ion GO:0010038 158 84 2,000 6,311E-03 0,05753149 ! T cell activation GO:0042110 189 84 2,000 6,311E-03 0,05731762 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 6,407E-03 0,05797218 ! mitochondrial membrane organization GO:0007006 60 27 1,000 6,407E-03 0,05775826 ! response to starvation GO:0042594 47 27 1,000 6,407E-03 0,05754592 ! cellular response to oxidative stress GO:0034599 43 27 1,000 6,407E-03 0,05733512 ! cellular response to nutrient levels GO:0031669 45 27 1,000 6,407E-03 0,05712587 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 6,407E-03 0,05691814 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 6,88E-03 0,06089722 ! negative regulation of protein modification process GO:0031400 66 28 1,000 6,88E-03 0,06067737 ! base-excision repair GO:0006284 41 28 1,000 6,88E-03 0,06045911 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 6,88E-03 0,06024241 ! mitochondrion organization GO:0007005 159 87 2,000 6,953E-03 0,06066674 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 7,368E-03 0,064058 ! respiratory gaseous exchange GO:0007585 61 29 1,000 7,368E-03 0,06383084 ! response to inorganic substance GO:0010035 173 90 2,000 7,633E-03 0,06588802 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 1,000 7,872E-03 0,06771173 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nicotinamide metabolic process GO:0006769 56 30 1,000 7,872E-03 0,06747415 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 1,000 7,872E-03 0,06723822 ! regulation of cell adhesion GO:0030155 241 92 2,000 8,106E-03 0,06900376 ! alkaloid metabolic process GO:0009820 57 31 1,000 8,39E-03 0,07116939 ! cell junction assembly GO:0034329 85 31 1,000 8,39E-03 0,07092313 ! male gonad development GO:0008584 56 31 1,000 8,39E-03 0,07067857 ! iron ion homeostasis GO:0055072 60 31 1,000 8,39E-03 0,07043569 ! detection of light stimulus GO:0009583 44 31 1,000 8,39E-03 0,07019447 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 8,39E-03 0,0699549 ! ensheathment of neurons GO:0007272 64 31 1,000 8,39E-03 0,06971696 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 8,39E-03 0,06948063 ! response to heat GO:0009408 54 31 1,000 8,39E-03 0,0692459 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 8,849E-03 0,07278988 ! spindle organization GO:0007051 50 32 1,000 8,923E-03 0,07315406 ! metanephros development GO:0001656 81 32 1,000 8,923E-03 0,0729094 ! response to mechanical stimulus GO:0009612 60 32 1,000 8,923E-03 0,07266637 ! hexose biosynthetic process GO:0019319 53 32 1,000 8,923E-03 0,07242495 ! peripheral nervous system development GO:0007422 68 32 1,000 8,923E-03 0,07218514 ! hindbrain development GO:0030902 65 32 1,000 8,923E-03 0,0719469 ! transcription initiation GO:0006352 171 97 2,000 9,366E-03 0,07526522 ! regulation of pH GO:0006885 56 33 1,000 9,472E-03 0,07586611 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 9,472E-03 0,07561818 ! response to ionizing radiation GO:0010212 74 33 1,000 9,472E-03 0,07537187 ! pyridine nucleotide metabolic process GO:0019362 60 33 1,000 9,472E-03 0,07512716 ! leukocyte differentiation GO:0002521 232 98 2,000 9,631E-03 0,07614063 ! spliceosome assembly GO:0000245 75 34 1,000 0,01003447 0,07907807 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01061182 0,08335911 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01120355 0,08772523 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01120355 0,08744496 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01120355 0,08716647 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01180951 0,0915893 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01180951 0,09129946 ! cell junction organization GO:0034330 96 37 1,000 0,01180951 0,09101145 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01242956 0,09548875 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01306358 0,1000449 ! mammary gland development GO:0030879 93 40 1,000 0,01371142 0,10467811 ! nucleus organization GO:0006997 73 40 1,000 0,01371142 0,10435201 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01371142 0,10402794 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,01437295 0,10870935 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01437295 0,10837383 ! RNA modification GO:0009451 64 41 1,000 0,01437295 0,10804037 ! ear morphogenesis GO:0042471 64 42 1,000 0,01504804 0,112768 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,01504804 0,11242315 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01504804 0,11208039 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,01504804 0,11173972 ! cytokinesis GO:0000910 84 42 1,000 0,01504804 0,11140112 ! epithelial cell differentiation GO:0030855 83 43 1,000 0,01573656 0,11614628 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01573656 0,11579644 ! glucose transport GO:0015758 66 43 1,000 0,01573656 0,11544871 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01573656 0,11510305 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01573656 0,11475946 ! neuron migration GO:0001764 85 43 1,000 0,01573656 0,11441791 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,01643838 0,11916603 ! hexose transport GO:0008645 68 44 1,000 0,01643838 0,11881346 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,01643838 0,11846298 ! phagocytosis GO:0006909 105 44 1,000 0,01643838 0,11811456 ! heterocycle biosynthetic process GO:0018130 76 44 1,000 0,01643838 0,11776818 ! double-strand break repair GO:0006302 85 44 1,000 0,01643838 0,11742383 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01715335 0,12217389 ! B cell differentiation GO:0030183 124 45 1,000 0,01715335 0,12181874 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 1,000 0,01715335 0,12146564 ! glycolysis GO:0006096 71 46 1,000 0,01788137 0,12625488 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01788137 0,12589103 ! cell growth GO:0016049 90 46 1,000 0,01788137 0,12552928 ! neural tube development GO:0021915 91 47 1,000 0,01862229 0,13035606 ! response to insulin stimulus GO:0032868 98 47 1,000 0,01862229 0,12998361 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,019376 0,13485915 ! mitochondrial transport GO:0006839 94 48 1,000 0,019376 0,13447603 ! cellular component disassembly GO:0022411 89 48 1,000 0,019376 0,13409508 ! male sex differentiation GO:0046661 93 48 1,000 0,019376 0,13371628 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02014235 0,13861344 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,02014235 0,13822408 ! protein homooligomerization GO:0051260 84 49 1,000 0,02014235 0,13783689 ! regulation of action potential GO:0001508 102 50 1,000 0,02092124 0,142767 ! endocrine system development GO:0035270 109 50 1,000 0,02092124 0,14236932 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,02092124 0,14197385 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,02092124 0,14158057 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,02092124 0,14118946 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02171253 0,14612589 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02203048 0,14785842 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02203048 0,14745333 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02203048 0,14705045 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02203048 0,14664977 ! neuron fate determination GO:0048664 7 5 0,000 0,02203048 0,14625126 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02203048 0,14585492 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02203048 0,14546072 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02203048 0,14506864 ! polyol transport GO:0015791 12 5 0,000 0,02203048 0,14467867 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02203048 0,14429079 ! response to superoxide GO:0000303 10 5 0,000 0,02203048 0,14390499 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02203048 0,14352124 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02203048 0,14313953 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02203048 0,14275985 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02203048 0,14238218 ! female meiosis GO:0007143 10 5 0,000 0,02203048 0,1420065 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02203048 0,1416328 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02203048 0,14126106 ! hypothalamus development GO:0021854 9 5 0,000 0,02203048 0,14089127 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02203048 0,14052341 ! cobalt ion transport GO:0006824 11 5 0,000 0,02203048 0,14015746 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02203048 0,13979342 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02203048 0,13943126 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02203048 0,13907097 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02203048 0,13871254 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02203048 0,13835595 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02203048 0,13800119 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02203048 0,13764825 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02203048 0,1372971 ! transposition GO:0032196 9 5 0,000 0,02203048 0,13694775 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02203048 0,13660016 ! negative chemotaxis GO:0050919 16 5 0,000 0,02203048 0,13625434 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02203048 0,13591026 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02203048 0,13556792 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02203048 0,1352273 ! behavioral response to pain GO:0048266 10 5 0,000 0,02203048 0,13488838 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02203048 0,13455116 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02203048 0,13421562 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02203048 0,13388175 ! micturition GO:0060073 9 5 0,000 0,02203048 0,13354954 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02203048 0,13321897 ! copulation GO:0007620 9 5 0,000 0,02203048 0,13289004 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02203048 0,13256272 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02203048 0,13223701 ! bioluminescence GO:0008218 9 5 0,000 0,02203048 0,1319129 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02203048 0,13159038 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02203048 0,13126943 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02203048 0,13095004 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02203048 0,1306322 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02203048 0,1303159 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02203048 0,13000112 ! grooming behavior GO:0007625 6 5 0,000 0,02203048 0,12968787 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02203048 0,12937612 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02203048 0,12906586 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02203048 0,12875709 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02203048 0,1284498 ! response to protozoan GO:0001562 13 5 0,000 0,02203048 0,12814396 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02203048 0,12783958 ! lymph vessel development GO:0001945 10 5 0,000 0,02203048 0,12753665 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02203048 0,12723514 ! endochondral ossification GO:0001958 17 5 0,000 0,02203048 0,12693506 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02203048 0,12663639 ! single strand break repair GO:0000012 8 5 0,000 0,02203048 0,12633912 ! parathyroid gland development GO:0060017 14 5 0,000 0,02203048 0,12604324 ! anagen GO:0042640 7 5 0,000 0,02203048 0,12574875 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02203048 0,12545563 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02203048 0,12516387 ! cytokine secretion GO:0050663 15 5 0,000 0,02203048 0,12487347 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02203048 0,12458441 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02203048 0,12429669 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02203048 0,12401029 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02203048 0,12372521 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02203048 0,12344143 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02203048 0,12315896 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02203048 0,12287777 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02203048 0,12259787 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02203048 0,12231924 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02203048 0,12204187 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02203048 0,12176576 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02203048 0,12149089 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02203048 0,12121726 ! microvillus organization GO:0032528 8 5 0,000 0,02203048 0,12094486 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02203048 0,12067369 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02203048 0,12040372 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02203048 0,12013497 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02203048 0,11986741 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02203048 0,11960103 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02203048 0,11933584 ! polyol catabolic process GO:0046174 9 5 0,000 0,02203048 0,11907182 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02203048 0,11880897 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02203048 0,11854728 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02203048 0,11828674 ! muscle cell migration GO:0014812 8 5 0,000 0,02203048 0,11802734 ! mitochondrial fission GO:0000266 8 5 0,000 0,02203048 0,11776907 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02203048 0,11751193 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02203048 0,11725591 ! mRNA transcription GO:0009299 10 5 0,000 0,02203048 0,11700101 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02203048 0,11674721 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02203048 0,11649451 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02203048 0,1162429 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02203048 0,11599238 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02203048 0,11574294 ! monocyte activation GO:0042117 10 5 0,000 0,02203048 0,11549456 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02203048 0,11524725 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02203048 0,11500099 ! response to food GO:0032094 6 5 0,000 0,02203048 0,11475579 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02203048 0,11451163 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02203048 0,1142685 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02203048 0,11402641 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02203048 0,11378534 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02203048 0,11354528 ! forebrain neuron development GO:0021884 13 5 0,000 0,02203048 0,11330624 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02203048 0,1130682 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02203048 0,11283116 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02203048 0,11259511 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02203048 0,11236005 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02203048 0,11212597 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02203048 0,11189286 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02203048 0,11166072 ! lipid glycosylation GO:0030259 7 5 0,000 0,02203048 0,11142953 ! nucleobase transport GO:0015851 6 5 0,000 0,02203048 0,11119931 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02203048 0,11097003 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02203048 0,1107417 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02203048 0,1105143 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02203048 0,11028784 ! basic amino acid transport GO:0015802 12 5 0,000 0,02203048 0,1100623 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02203048 0,10983768 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02203048 0,10961398 ! actin nucleation GO:0045010 11 5 0,000 0,02203048 0,10939119 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02203048 0,1091693 ! depurination GO:0045007 5 5 0,000 0,02203048 0,10894831 ! depyrimidination GO:0045008 10 5 0,000 0,02203048 0,10872821 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02203048 0,108509 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02203048 0,10829067 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02203048 0,10807322 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02203048 0,10785664 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02203048 0,10764093 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02203048 0,10742608 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02203048 0,10721208 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02203048 0,10699894 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02203048 0,10678664 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02203048 0,10657518 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02203048 0,10636456 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02203048 0,10615476 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02203048 0,1059458 ! response to arsenic GO:0046685 11 5 0,000 0,02203048 0,10573765 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02203048 0,10553032 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02203048 0,10532381 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02203048 0,1051181 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02203048 0,10491319 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02203048 0,10470908 ! response to mercury ion GO:0046689 8 5 0,000 0,02203048 0,10450576 ! response to cadmium ion GO:0046686 7 5 0,000 0,02203048 0,10430323 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02203048 0,10410148 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02203048 0,10390051 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02203048 0,10370032 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02203048 0,10350089 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02203048 0,10330224 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02203048 0,10310434 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02203048 0,1029072 ! decidualization GO:0046697 11 5 0,000 0,02203048 0,10271081 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02203048 0,10251517 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02203048 0,10232028 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02203048 0,10212612 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02203048 0,1019327 ! embryonic cleavage GO:0040016 6 5 0,000 0,02203048 0,10174001 ! peroxisome fission GO:0016559 5 5 0,000 0,02203048 0,10154805 ! histone demethylation GO:0016577 13 5 0,000 0,02203048 0,10135681 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02203048 0,10116629 ! mitotic recombination GO:0006312 9 5 0,000 0,02203048 0,10097648 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02203048 0,10078739 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02203048 0,100599 ! metaphase plate congression GO:0051310 7 5 0,000 0,02203048 0,10041132 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02203048 0,10022433 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02203048 0,10003804 ! enteric nervous system development GO:0048484 8 5 0,000 0,02203048 0,09985244 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02203048 0,09966753 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02203048 0,0994833 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02203048 0,09929975 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02203048 0,09911688 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02203048 0,09893468 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02203048 0,09875315 ! B cell homeostasis GO:0001782 13 5 0,000 0,02203048 0,09857228 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02203048 0,09839207 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02203048 0,09821253 ! metaphase GO:0051323 11 5 0,000 0,02203048 0,09803363 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02203048 0,09785539 GO:0030186|melatonin metabolic process, ! cellular response to nutrient GO:0031670 8 5 0,000 0,02203048 0,09767779 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02203048 0,09750084 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02203048 0,09732453 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02203048 0,09714885 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02203048 0,09697381 ! response to redox state GO:0051775 6 5 0,000 0,02203048 0,0967994 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02203048 0,09662561 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02203048 0,09645245 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02203048 0,0962799 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02203048 0,09610797 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02203048 0,09593666 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02203048 0,09576595 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02203048 0,09559585 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02203048 0,09542636 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02203048 0,09525746 ! striatum development GO:0021756 14 5 0,000 0,02203048 0,09508916 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02203048 0,09492145 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02203048 0,09475434 ! glial cell migration GO:0008347 10 5 0,000 0,02203048 0,09458781 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02203048 0,09442187 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02203048 0,09425651 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02203048 0,09409172 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02203048 0,09392751 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02203048 0,09376388 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02203048 0,09360081 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02203048 0,09343831 ! neuroprotection GO:0043526 8 5 0,000 0,02203048 0,09327637 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02203048 0,09311499 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02203048 0,09295417 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02203048 0,0927939 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02203048 0,09263419 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02203048 0,09247503 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02203048 0,09231641 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02203048 0,09215833 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02203048 0,09200079 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02203048 0,0918438 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02203048 0,09168733 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02203048 0,0915314 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02203048 0,091376 ! spindle assembly GO:0051225 6 5 0,000 0,02203048 0,09122113 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02203048 0,09106678 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02203048 0,09091295 ! protein palmitoylation GO:0018345 12 5 0,000 0,02203048 0,09075964 ! drug metabolic process GO:0017144 7 5 0,000 0,02203048 0,09060684 ! stem cell division GO:0017145 11 5 0,000 0,02203048 0,09045456 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02203048 0,09030279 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02203048 0,09015153 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02203048 0,09000078 ! Notch signaling pathway GO:0007219 111 52 1,000 0,02251609 0,09183107 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,02251609 0,09167801 ! vesicle organization GO:0016050 127 53 1,000 0,02333181 0,09484128 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,02333181 0,09468374 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 1,000 0,02333181 0,09452672 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,02415956 0,09771823 ! regulation of cell shape GO:0008360 142 54 1,000 0,02415956 0,09755671 ! cell recognition GO:0008037 98 55 1,000 0,02499923 0,10078071 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02585068 0,10404153 ! glucose catabolic process GO:0006007 88 56 1,000 0,02585068 0,10387041 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02637836 0,10581663 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02637836 0,10564316 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02637836 0,10547026 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02637836 0,10529792 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02637836 0,10512615 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02637836 0,10495493 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02637836 0,10478427 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02637836 0,10461417 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02637836 0,10444461 ! response to oxygen radical GO:0000305 11 6 0,000 0,02637836 0,10427561 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02637836 0,10410715 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02637836 0,10393924 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02637836 0,10377186 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02637836 0,10360503 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02637836 0,10343873 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02637836 0,10327296 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02637836 0,10310772 ! forebrain regionalization GO:0021871 9 6 0,000 0,02637836 0,10294301 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02637836 0,10277883 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02637836 0,10261517 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02637836 0,10245203 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02637836 0,10228941 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02637836 0,1021273 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02637836 0,10196571 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02637836 0,10180462 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02637836 0,10164405 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02637836 0,10148398 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02637836 0,10132441 ! malate metabolic process GO:0006108 13 6 0,000 0,02637836 0,10116535 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02637836 0,10100678 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02637836 0,10084871 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02637836 0,10069114 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02637836 0,10053405 ! protein refolding GO:0042026 15 6 0,000 0,02637836 0,10037746 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02637836 0,10022135 ! opsonization GO:0008228 8 6 0,000 0,02637836 0,10006573 ! mating behavior GO:0007617 7 6 0,000 0,02637836 0,09991058 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02637836 0,09975592 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02637836 0,09960174 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02637836 0,09944804 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02637836 0,0992948 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02637836 0,09914204 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02637836 0,09898975 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02637836 0,09883793 ! toxin metabolic process GO:0009404 11 6 0,000 0,02637836 0,09868657 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02637836 0,09853567 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02637836 0,09838523 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02637836 0,09823525 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02637836 0,09808573 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02637836 0,09793667 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02637836 0,09778805 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02637836 0,09763989 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02637836 0,09749217 ! thymic T cell selection GO:0045061 16 6 0,000 0,02637836 0,09734491 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02637836 0,09719808 ! protein lipoylation GO:0009249 10 6 0,000 0,02637836 0,0970517 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02637836 0,09690576 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02637836 0,09676025 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02637836 0,09661518 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02637836 0,09647055 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02637836 0,09632635 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02637836 0,09618258 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02637836 0,09603924 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02637836 0,09589632 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02637836 0,09575383 ! hyperosmotic response GO:0006972 10 6 0,000 0,02637836 0,09561176 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02637836 0,09547011 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02637836 0,09532889 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02637836 0,09518808 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02637836 0,09504768 ! urea metabolic process GO:0019627 7 6 0,000 0,02637836 0,0949077 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02637836 0,09476813 ! neutrophil activation GO:0042119 7 6 0,000 0,02637836 0,09462897 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02637836 0,09449022 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02637836 0,09435187 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02637836 0,09421393 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02637836 0,09407639 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02637836 0,09393925 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02637836 0,09380251 ! neuron apoptosis GO:0051402 15 6 0,000 0,02637836 0,09366617 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02637836 0,09353023 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02637836 0,09339468 ! folic acid transport GO:0015884 14 6 0,000 0,02637836 0,09325952 ! carnitine transport GO:0015879 10 6 0,000 0,02637836 0,09312475 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02637836 0,09299037 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02637836 0,09285638 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02637836 0,09272277 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02637836 0,09258955 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02637836 0,09245671 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02637836 0,09232425 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02637836 0,09219217 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02637836 0,09206047 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02637836 0,09192914 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02637836 0,09179819 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02637836 0,09166761 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02637836 0,0915374 ! response to UV-C GO:0010225 14 6 0,000 0,02637836 0,09140756 ! astrocyte development GO:0014002 16 6 0,000 0,02637836 0,09127808 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02637836 0,09114898 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02637836 0,09102024 ! interaction with symbiont GO:0051702 14 6 0,000 0,02637836 0,09089186 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02637836 0,09076384 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02637836 0,09063618 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02637836 0,09050889 ! response to copper ion GO:0046688 10 6 0,000 0,02637836 0,09038195 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02637836 0,09025536 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02637836 0,09012913 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02637836 0,09000325 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02637836 0,08987772 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02637836 0,08975254 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02637836 0,08962772 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02637836 0,08950323 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02637836 0,08937909 ! hair follicle maturation GO:0048820 8 6 0,000 0,02637836 0,0892553 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02637836 0,08913185 ! Schwann cell development GO:0014044 15 6 0,000 0,02637836 0,08900874 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02637836 0,08888597 ! response to pheromone GO:0019236 6 6 0,000 0,02637836 0,08876354 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02637836 0,08864144 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02637836 0,08851968 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02637836 0,08839825 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02637836 0,08827716 ! subpallium development GO:0021544 15 6 0,000 0,02637836 0,0881564 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02637836 0,08803597 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02637836 0,08791586 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02637836 0,08779609 ! G2 phase GO:0051319 16 6 0,000 0,02637836 0,08767664 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02637836 0,08755751 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02637836 0,08743871 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02637836 0,08732023 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02637836 0,08720207 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02637836 0,08708423 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02637836 0,0869667 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02637836 0,0868495 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02637836 0,08673261 ! receptor internalization GO:0031623 11 6 0,000 0,02637836 0,08661603 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02637836 0,08649977 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02637836 0,08638382 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02637836 0,08626818 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02637836 0,08615284 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02637836 0,08603782 ! protein deubiquitination GO:0016579 16 6 0,000 0,02637836 0,0859231 ! protein destabilization GO:0031648 9 6 0,000 0,02637836 0,08580869 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02637836 0,08569458 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02637836 0,08558078 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02637836 0,08546728 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02637836 0,08535408 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02637836 0,08524117 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02637836 0,08512857 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02637836 0,08501626 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02637836 0,08490425 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02637836 0,08479254 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02637836 0,08468111 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02637836 0,08456998 ! neural plate development GO:0001840 9 6 0,000 0,02637836 0,08445914 ! catecholamine transport GO:0051937 9 6 0,000 0,02637836 0,0843486 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02637836 0,08423834 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02637836 0,08412836 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02637836 0,08401868 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02637836 0,08390928 ! maternal placenta development GO:0001893 12 6 0,000 0,02637836 0,08380017 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02637836 0,08369133 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02637836 0,08358279 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02637836 0,08347452 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02637836 0,08336653 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02637836 0,08325882 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02637836 0,08315139 GO:0055081|anion homeostasis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,0267138 0,08410028 ! muscle fiber development GO:0048747 131 57 1,000 0,0267138 0,08399205 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,0267138 0,08388409 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,02758848 0,08651945 ! establishment of organelle localization GO:0051656 122 59 1,000 0,02847458 0,08918386 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,02937201 0,09187684 ! DNA catabolic process GO:0006308 94 60 1,000 0,02937201 0,09175935 ! kidney development GO:0001822 133 60 1,000 0,02937201 0,09164216 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,03028063 0,09435659 ! camera-type eye development GO:0043010 126 61 1,000 0,03028063 0,09423639 ! tRNA transcription GO:0009304 17 7 0,000 0,03070703 0,09544181 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03070703 0,09532054 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03070703 0,09519957 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03070703 0,09507892 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03070703 0,09495856 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03070703 0,09483851 ! sleep GO:0030431 16 7 0,000 0,03070703 0,09471877 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03070703 0,09459932 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03070703 0,09448018 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03070703 0,09436134 ! prostate gland development GO:0030850 14 7 0,000 0,03070703 0,09424279 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03070703 0,09412455 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03070703 0,0940066 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03070703 0,09388894 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03070703 0,09377158 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03070703 0,09365451 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03070703 0,09353774 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03070703 0,09342125 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03070703 0,09330506 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03070703 0,09318915 ! glycolipid transport GO:0046836 11 7 0,000 0,03070703 0,09307353 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03070703 0,0929582 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03070703 0,09284315 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03070703 0,09272839 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03070703 0,09261391 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03070703 0,09249971 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03070703 0,09238579 ! mRNA stabilization GO:0048255 18 7 0,000 0,03070703 0,09227216 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03070703 0,0921588 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03070703 0,09204572 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03070703 0,09193292 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03070703 0,0918204 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03070703 0,09170815 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03070703 0,09159617 ! lipoprotein transport GO:0042953 14 7 0,000 0,03070703 0,09148447 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03070703 0,09137304 ! rhythmic behavior GO:0007622 17 7 0,000 0,03070703 0,09126188 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03070703 0,09115099 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03070703 0,09104037 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03070703 0,09093002 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03070703 0,09081993 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03070703 0,09071011 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03070703 0,09060056 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03070703 0,09049127 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03070703 0,09038225 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03070703 0,09027348 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03070703 0,09016498 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03070703 0,09005674 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03070703 0,08994876 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03070703 0,08984104 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03070703 0,08973357 ! spinal cord patterning GO:0021511 14 7 0,000 0,03070703 0,08962636 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03070703 0,08951941 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03070703 0,08941271 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03070703 0,08930627 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03070703 0,08920008 ! adrenal gland development GO:0030325 17 7 0,000 0,03070703 0,08909414 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03070703 0,08898845 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03070703 0,08888301 ! ovulation GO:0030728 10 7 0,000 0,03070703 0,08877783 ! adenohypophysis development GO:0021984 11 7 0,000 0,03070703 0,08867289 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03070703 0,0885682 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03070703 0,08846376 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 21 7 0,000 0,03070703 0,08835956 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03070703 0,08825561 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03070703 0,0881519 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03070703 0,08804843 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03070703 0,08794521 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03070703 0,08784223 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03070703 0,08773949 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03070703 0,08763699 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03070703 0,08753473 ! galactose metabolic process GO:0006012 13 7 0,000 0,03070703 0,08743271 ! vesicle fusion GO:0006906 20 7 0,000 0,03070703 0,08733092 ! response to dietary excess GO:0002021 8 7 0,000 0,03070703 0,08722938 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03070703 0,08712807 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03070703 0,08702699 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03070703 0,08692615 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03070703 0,08682554 ! organ growth GO:0035265 15 7 0,000 0,03070703 0,08672516 ! nucleoside transport GO:0015858 11 7 0,000 0,03070703 0,08662502 ! nucleoside salvage GO:0043174 11 7 0,000 0,03070703 0,0865251 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03070703 0,08642542 ! male sex determination GO:0030238 15 7 0,000 0,03070703 0,08632597 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03070703 0,08622674 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,03070703 0,08612774 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03070703 0,08602897 ! rRNA modification GO:0000154 14 7 0,000 0,03070703 0,08593043 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03070703 0,08583211 ! spindle checkpoint GO:0031577 16 7 0,000 0,03070703 0,08573402 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03070703 0,08563615 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03070703 0,0855385 ! monocyte differentiation GO:0030224 16 7 0,000 0,03070703 0,08544108 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03070703 0,08534387 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03070703 0,08524689 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03070703 0,08515013 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03070703 0,08505359 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03070703 0,08495726 ! fibrinolysis GO:0042730 11 7 0,000 0,03070703 0,08486116 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03070703 0,08476527 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03070703 0,0846696 ! eating behavior GO:0042755 8 7 0,000 0,03070703 0,08457414 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03070703 0,0844789 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03070703 0,08438387 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03070703 0,08428906 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03070703 0,08419446 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03070703 0,08410007 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03070703 0,0840059 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03070703 0,08391193 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03070703 0,08381817 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03070703 0,08372463 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03070703 0,08363129 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03070703 0,08353816 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03070703 0,08344523 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03070703 0,08335252 ! histone ubiquitination GO:0016574 9 7 0,000 0,03070703 0,08326 ! regulation of meiosis GO:0040020 12 7 0,000 0,03070703 0,0831677 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03070703 0,0830756 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03070703 0,0829837 GO:0002714|positive regulation of B cell mediated immunity, ! membrane to membrane docking GO:0022614 14 7 0,000 0,03070703 0,082892 ! transcription termination GO:0006353 14 7 0,000 0,03070703 0,08280051 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03070703 0,08270922 ! anaphase GO:0051322 18 7 0,000 0,03070703 0,08261813 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03070703 0,08252724 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03070703 0,08243655 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03070703 0,08234606 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03070703 0,08225577 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03070703 0,08216568 ! diuresis GO:0030146 12 7 0,000 0,03070703 0,08207578 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03070703 0,08198608 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03070703 0,08189658 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03070703 0,08180727 ! antibiotic transport GO:0042891 9 7 0,000 0,03070703 0,08171815 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03070703 0,08162923 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03070703 0,0815405 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03070703 0,08145197 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03070703 0,08136363 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03070703 0,08127548 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03070703 0,08118752 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03070703 0,08109975 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03070703 0,08101216 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03070703 0,08092477 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03070703 0,08083757 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03070703 0,08075055 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03070703 0,08066373 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03070703 0,08057708 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03070703 0,08049063 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03070703 0,08040436 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03070703 0,08031827 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03070703 0,08023237 ! muscle adaptation GO:0043500 13 7 0,000 0,03070703 0,08014665 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03070703 0,08006111 ! retina homeostasis GO:0001895 12 7 0,000 0,03070703 0,07997576 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03070703 0,07989059 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03070703 0,0798056 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03070703 0,07972079 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03070703 0,07963616 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,03120033 0,08082969 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,03120033 0,08074407 ! regulation of mitosis GO:0007088 112 63 1,000 0,032131 0,08306458 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,032131 0,08297677 ! water-soluble vitamin metabolic process GO:0006767 107 63 1,000 0,032131 0,08288915 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,03307252 0,08522803 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,03402478 0,08758961 ! ear development GO:0043583 114 66 1,000 0,03498767 0,08997356 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,03498767 0,08987895 ! gonad development GO:0008406 115 66 1,000 0,03498767 0,08978454 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03501657 0,08976441 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03501657 0,08967032 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,03501657 0,08957642 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03501657 0,08948272 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03501657 0,08938922 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03501657 0,08929591 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03501657 0,0892028 ! male meiosis GO:0007140 9 8 0,000 0,03501657 0,08910988 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03501657 0,08901715 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03501657 0,08892462 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03501657 0,08883228 ! meiotic prophase I GO:0007128 14 8 0,000 0,03501657 0,08874013 ! response to zinc ion GO:0010043 12 8 0,000 0,03501657 0,08864817 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03501657 0,0885564 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03501657 0,08846482 ! oligopeptide transport GO:0006857 16 8 0,000 0,03501657 0,08837343 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03501657 0,08828223 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03501657 0,08819122 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03501657 0,08810039 ! signal peptide processing GO:0006465 12 8 0,000 0,03501657 0,08800976 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03501657 0,0879193 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03501657 0,08782904 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03501657 0,08773896 ! succinate metabolic process GO:0006105 17 8 0,000 0,03501657 0,08764906 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03501657 0,08755935 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03501657 0,08746982 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03501657 0,08738047 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03501657 0,08729131 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03501657 0,08720233 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03501657 0,08711353 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03501657 0,08702491 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03501657 0,08693647 ! reflex GO:0060004 17 8 0,000 0,03501657 0,08684821 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03501657 0,08676012 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03501657 0,08667222 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03501657 0,0865845 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03501657 0,08649695 ! pigment granule organization GO:0048753 17 8 0,000 0,03501657 0,08640958 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03501657 0,08632238 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03501657 0,08623536 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03501657 0,08614852 ! histidine catabolic process GO:0006548 10 8 0,000 0,03501657 0,08606185 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03501657 0,08597536 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03501657 0,08588904 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03501657 0,08580289 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03501657 0,08571692 ! melanin metabolic process GO:0006582 17 8 0,000 0,03501657 0,08563111 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03501657 0,08554548 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03501657 0,08546002 ! macrophage activation GO:0042116 13 8 0,000 0,03501657 0,08537473 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03501657 0,08528961 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03501657 0,08520466 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03501657 0,08511988 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03501657 0,08503527 ! purine salvage GO:0043101 12 8 0,000 0,03501657 0,08495083 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03501657 0,08486655 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03501657 0,08478244 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03501657 0,0846985 ! osteoblast development GO:0002076 17 8 0,000 0,03501657 0,08461472 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03501657 0,08453111 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03501657 0,08444766 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03501657 0,08436438 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03501657 0,08428126 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03501657 0,08419831 ! response to UV-B GO:0010224 17 8 0,000 0,03501657 0,08411552 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03501657 0,08403289 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03501657 0,08395042 ! intermediate filament organization GO:0045109 12 8 0,000 0,03501657 0,08386812 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03501657 0,08378598 ! cellular extravasation GO:0045123 13 8 0,000 0,03501657 0,08370399 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03501657 0,08362217 ! response to antibiotic GO:0046677 11 8 0,000 0,03501657 0,08354051 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03501657 0,08345901 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03501657 0,08337766 ! DNA topological change GO:0006265 12 8 0,000 0,03501657 0,08329648 ! response to tropane GO:0014073 15 8 0,000 0,03501657 0,08321545 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03501657 0,08313458 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03501657 0,08305387 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03501657 0,08297331 ! mast cell activation GO:0045576 14 8 0,000 0,03501657 0,08289291 ! gas homeostasis GO:0033483 14 8 0,000 0,03501657 0,08281266 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03501657 0,08273257 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03501657 0,08265264 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03501657 0,08257286 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03501657 0,08249323 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03501657 0,08241376 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03501657 0,08233444 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03501657 0,08225527 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03501657 0,08217626 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03501657 0,08209739 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03501657 0,08201868 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03501657 0,08194012 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03501657 0,08186171 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03501657 0,08178344 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03501657 0,08170533 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03501657 0,08162737 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03501657 0,08154955 ! hormone catabolic process GO:0042447 17 8 0,000 0,03501657 0,08147189 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03501657 0,08139437 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03501657 0,081317 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03501657 0,08123977 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03501657 0,0811627 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03501657 0,08108576 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03501657 0,08100898 ! adult feeding behavior GO:0008343 10 8 0,000 0,03501657 0,08093234 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03501657 0,08085584 ! ATP catabolic process GO:0006200 11 8 0,000 0,03501657 0,08077949 ! blastocyst growth GO:0001832 19 8 0,000 0,03501657 0,08070328 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03501657 0,08062722 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03501657 0,0805513 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03501657 0,08047552 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03501657 0,08039989 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03501657 0,0803244 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03501657 0,08024905 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03501657 0,08017384 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03501657 0,08009877 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03501657 0,08002384 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03501657 0,07994905 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03501657 0,0798744 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03501657 0,07979989 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03501657 0,07972552 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03501657 0,07965129 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03501657 0,07957719 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03501657 0,07950324 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03501657 0,07942942 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03501657 0,07935573 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,03596107 0,08142067 ! activation of MAPK activity GO:0000187 124 67 1,000 0,03596107 0,08134528 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03596107 0,08127003 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,03596107 0,08119492 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03596107 0,08111995 ! hexose catabolic process GO:0019320 113 68 1,000 0,03694488 0,08326231 ! extracellular matrix organization GO:0030198 146 68 1,000 0,03694488 0,08318557 ! cell projection assembly GO:0030031 138 68 1,000 0,03694488 0,08310897 ! negative regulation of cell size GO:0045792 144 69 1,000 0,03793898 0,08526673 ! urogenital system development GO:0001655 149 69 1,000 0,03793898 0,08518836 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,03793898 0,08511013 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,03793898 0,08503205 ! developmental maturation GO:0021700 128 69 1,000 0,03793898 0,08495411 ! germ cell development GO:0007281 133 70 1,000 0,03894326 0,08712307 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,03894326 0,08704336 ! axon extension GO:0048675 16 9 0,000 0,03930708 0,08777622 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03930708 0,08769606 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03930708 0,08761605 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03930708 0,08753618 ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03930708 0,08745645 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03930708 0,08737687 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03930708 0,08729744 ! reproductive behavior GO:0019098 22 9 0,000 0,03930708 0,08721815 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03930708 0,08713901 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03930708 0,08706 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03930708 0,08698115 ! UTP metabolic process GO:0046051 10 9 0,000 0,03930708 0,08690243 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03930708 0,08682386 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03930708 0,08674542 ! artery development GO:0060840 25 9 0,000 0,03930708 0,08666713 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03930708 0,08658899 ! regulation of glycolysis GO:0006110 20 9 0,000 0,03930708 0,08651098 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03930708 0,08643311 ! equilibrioception GO:0050957 20 9 0,000 0,03930708 0,08635538 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03930708 0,08627779 ! chemosensory behavior GO:0007635 21 9 0,000 0,03930708 0,08620035 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03930708 0,08612304 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03930708 0,08604587 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03930708 0,08596883 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03930708 0,08589194 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03930708 0,08581518 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03930708 0,08573856 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03930708 0,08566207 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03930708 0,08558573 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03930708 0,08550952 ! protein targeting to ER GO:0045047 25 9 0,000 0,03930708 0,08543344 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03930708 0,0853575 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03930708 0,08528169 ! T cell selection GO:0045058 27 9 0,000 0,03930708 0,08520602 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,03930708 0,08513048 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03930708 0,08505508 ! glycine catabolic process GO:0006546 15 9 0,000 0,03930708 0,08497981 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03930708 0,08490467 ! endosome organization GO:0007032 20 9 0,000 0,03930708 0,08482967 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03930708 0,0847548 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03930708 0,08468006 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03930708 0,08460545 ! mannose metabolic process GO:0006013 13 9 0,000 0,03930708 0,08453097 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03930708 0,08445663 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03930708 0,08438241 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03930708 0,08430833 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03930708 0,08423437 ! receptor clustering GO:0043113 20 9 0,000 0,03930708 0,08416055 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03930708 0,08408685 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03930708 0,08401329 ! retinol metabolic process GO:0042572 20 9 0,000 0,03930708 0,08393985 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03930708 0,08386654 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03930708 0,08379336 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03930708 0,0837203 ! macrophage differentiation GO:0030225 15 9 0,000 0,03930708 0,08364737 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03930708 0,08357457 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03930708 0,0835019 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03930708 0,08342935 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03930708 0,08335693 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03930708 0,08328464 ! response to amine stimulus GO:0014075 13 9 0,000 0,03930708 0,08321247 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03930708 0,08314042 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03930708 0,0830685 ! erythrocyte development GO:0048821 17 9 0,000 0,03930708 0,0829967 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03930708 0,08292503 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03930708 0,08285348 ! renal water homeostasis GO:0003091 15 9 0,000 0,03930708 0,08278206 ! postreplication repair GO:0006301 25 9 0,000 0,03930708 0,08271075 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03930708 0,08263957 ! icosanoid secretion GO:0032309 15 9 0,000 0,03930708 0,08256852 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03930708 0,08249758 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03930708 0,08242677 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03930708 0,08235608 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03930708 0,08228551 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03930708 0,08221506 ! sterol catabolic process GO:0016127 14 9 0,000 0,03930708 0,08214473 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03930708 0,08207452 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03930708 0,08200443 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03930708 0,08193446 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03930708 0,08186461 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03930708 0,08179488 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03930708 0,08172526 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03930708 0,08165577 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03930708 0,08158639 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03930708 0,08151714 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03930708 0,08144799 ! purine base metabolic process GO:0006144 25 9 0,000 0,03930708 0,08137897 ! pigment granule transport GO:0051904 17 9 0,000 0,03930708 0,08131006 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03930708 0,08124127 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03930708 0,0811726 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03930708 0,08110404 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03930708 0,0810356 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03930708 0,08096727 ! mitochondrion localization GO:0051646 18 9 0,000 0,03930708 0,08089906 ! appendage morphogenesis GO:0035107 150 72 1,000 0,04098195 0,08427516 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,04098195 0,08420428 ! actin filament organization GO:0007015 167 72 1,000 0,04098195 0,08413352 ! coenzyme biosynthetic process GO:0009108 119 72 1,000 0,04098195 0,08406288 ! appendage development GO:0048736 151 73 1,000 0,04201613 0,08611191 GO:0060173|limb development, ! organelle localization GO:0051640 155 74 1,000 0,04306006 0,08817748 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04357862 0,08916464 ! regulation of developmental growth GO:0048638 16 10 0,000 0,04357862 0,08909002 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,04357862 0,08901553 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04357862 0,08894117 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04357862 0,08886693 ! associative learning GO:0008306 21 10 0,000 0,04357862 0,08879281 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04357862 0,08871882 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04357862 0,08864494 ! phosphate transport GO:0006817 24 10 0,000 0,04357862 0,0885712 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04357862 0,08849757 ! CTP metabolic process GO:0046036 11 10 0,000 0,04357862 0,08842407 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04357862 0,08835069 ! GTP metabolic process GO:0046039 11 10 0,000 0,04357862 0,08827743 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04357862 0,08820429 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04357862 0,08813127 ! social behavior GO:0035176 29 10 0,000 0,04357862 0,08805838 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04357862 0,0879856 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04357862 0,08791295 ! androgen metabolic process GO:0008209 17 10 0,000 0,04357862 0,08784041 ! phospholipid efflux GO:0033700 19 10 0,000 0,04357862 0,087768 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04357862 0,0876957 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04357862 0,08762352 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04357862 0,08755146 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04357862 0,08747952 ! lung alveolus development GO:0048286 26 10 0,000 0,04357862 0,0874077 ! pathogenesis GO:0009405 17 10 0,000 0,04357862 0,087336 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04357862 0,08726441 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04357862 0,08719294 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04357862 0,08712159 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04357862 0,08705035 ! endoderm development GO:0007492 18 10 0,000 0,04357862 0,08697923 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04357862 0,08690823 ! arginine catabolic process GO:0006527 17 10 0,000 0,04357862 0,08683734 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04357862 0,08676657 ! proline metabolic process GO:0006560 13 10 0,000 0,04357862 0,08669591 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04357862 0,08662537 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04357862 0,08655494 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04357862 0,08648463 ! V(D)J recombination GO:0033151 34 10 0,000 0,04357862 0,08641443 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04357862 0,08634435 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04357862 0,08627438 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04357862 0,08620452 ! B cell proliferation GO:0042100 19 10 0,000 0,04357862 0,08613477 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04357862 0,08606514 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04357862 0,08599562 ! multicellular organism growth GO:0035264 19 10 0,000 0,04357862 0,08592621 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04357862 0,08585692 ! ruffle organization GO:0031529 17 10 0,000 0,04357862 0,08578773 ! epithelial cell development GO:0002064 21 10 0,000 0,04357862 0,08571866 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04357862 0,0856497 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04357862 0,08558085 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04357862 0,08551211 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04357862 0,08544348 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04357862 0,08537496 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04357862 0,08530655 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04357862 0,08523825 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04357862 0,08517006 ! protein heterooligomerization GO:0051291 17 10 0,000 0,04357862 0,08510198 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04357862 0,08503401 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04357862 0,08496614 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04357862 0,08489839 ! segment specification GO:0007379 15 10 0,000 0,04357862 0,08483074 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04357862 0,0847632 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04357862 0,08469577 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04357862 0,08462844 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04357862 0,08456122 ! response to dsRNA GO:0043331 23 10 0,000 0,04357862 0,08449411 ! DNA ligation GO:0006266 18 10 0,000 0,04357862 0,0844271 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04357862 0,08436021 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04357862 0,08429341 ! melanosome localization GO:0032400 16 10 0,000 0,04357862 0,08422672 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04357862 0,08416014 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04357862 0,08409366 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04357862 0,08402729 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04357862 0,08396102 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04357862 0,08389486 ! induction of an organ GO:0001759 17 10 0,000 0,04357862 0,0838288 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04357862 0,08376285 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04357862 0,083697 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04357862 0,08363125 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04357862 0,0835656 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04357862 0,08350006 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04357862 0,08343462 ! salivary gland development GO:0007431 28 10 0,000 0,04357862 0,08336929 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04357862 0,08330405 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04357862 0,08323892 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04357862 0,08317389 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04357862 0,08310896 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04357862 0,08304413 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04357862 0,08297941 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04357862 0,08291478 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04357862 0,08285026 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04357862 0,08278583 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04357862 0,08272151 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04357862 0,08265728 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,04357862 0,08259316 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04357862 0,08252913 ! blastocyst formation GO:0001825 18 10 0,000 0,04357862 0,0824652 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04357862 0,08240138 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04357862 0,08233765 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04357862 0,08227402 ! response to nicotine GO:0035094 20 10 0,000 0,04357862 0,08221049 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04357862 0,08214705 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04357862 0,08208372 ! reproductive structure development GO:0048608 131 75 1,000 0,04411364 0,08302745 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,04411364 0,08296353 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,04411364 0,08289972 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,04517677 0,08483231 ! regulation of blood pressure GO:0008217 134 76 1,000 0,04517677 0,08476716 ! amine catabolic process GO:0009310 136 77 1,000 0,04624932 0,08671305 ! neurotransmitter transport GO:0006836 142 77 1,000 0,04624932 0,08664655 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,04624932 0,08658015 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,04624932 0,08651386 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0478313 0,08940464 ! respiratory burst GO:0045730 17 11 0,000 0,0478313 0,08933629 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0478313 0,08926804 ! neuron fate specification GO:0048665 18 11 0,000 0,0478313 0,0891999 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0478313 0,08913186 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0478313 0,08906392 ! thyroid gland development GO:0030878 26 11 0,000 0,0478313 0,08899609 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,0478313 0,08892836 ! synapsis GO:0007129 14 11 0,000 0,0478313 0,08886073 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0478313 0,08879321 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0478313 0,08872579 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,0478313 0,08865847 ! response to pain GO:0048265 27 11 0,000 0,0478313 0,08859126 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0478313 0,08852414 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0478313 0,08845713 ! bone resorption GO:0045453 16 11 0,000 0,0478313 0,08839022 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0478313 0,08832341 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,0478313 0,0882567 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0478313 0,08819009 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0478313 0,08812358 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0478313 0,08805717 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0478313 0,08799086 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0478313 0,08792465 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0478313 0,08785855 GO:0010833|telomere maintenance via telomere lengthening, ! UV protection GO:0009650 20 11 0,000 0,0478313 0,08779254 ! adult heart development GO:0007512 16 11 0,000 0,0478313 0,08772663 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0478313 0,08766081 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0478313 0,0875951 ! macroautophagy GO:0016236 19 11 0,000 0,0478313 0,08752949 ! temperature homeostasis GO:0001659 18 11 0,000 0,0478313 0,08746397 ! behavioral fear response GO:0001662 27 11 0,000 0,0478313 0,08739855 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0478313 0,08733323 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0478313 0,08726801 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0478313 0,08720288 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0478313 0,08713786 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0478313 0,08707293 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0478313 0,08700809 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0478313 0,08694335 ! regulation of organ growth GO:0046620 14 11 0,000 0,0478313 0,08687871 ! pigment granule localization GO:0051875 20 11 0,000 0,0478313 0,08681416 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0478313 0,08674971 ! vasoconstriction GO:0042310 20 11 0,000 0,0478313 0,08668536 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0478313 0,0866211 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0478313 0,08655694 ! embryonic axis specification GO:0000578 19 11 0,000 0,0478313 0,08649287 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0478313 0,08642889 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0478313 0,08636502 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0478313 0,08630123 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0478313 0,08623754 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0478313 0,08617394 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0478313 0,08611044 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0478313 0,08604703 ! prophase GO:0051324 17 11 0,000 0,0478313 0,08598371 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0478313 0,08592049 ! nucleosome positioning GO:0016584 15 11 0,000 0,0478313 0,08585736 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0478313 0,08579432 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0478313 0,08573138 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0478313 0,08566852 ! acid secretion GO:0046717 20 11 0,000 0,0478313 0,08560576 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0478313 0,08554309 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0478313 0,08548052 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0478313 0,08541803 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0478313 0,08535564 ! thymus development GO:0048538 29 11 0,000 0,0478313 0,08529333 ! cholesterol efflux GO:0033344 21 11 0,000 0,0478313 0,08523112 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0478313 0,085169 ! oocyte development GO:0048599 20 11 0,000 0,0478313 0,08510697 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0478313 0,08504503 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0478313 0,08498317 ! embryonic gut development GO:0048566 19 11 0,000 0,0478313 0,08492141 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0478313 0,08485974 ! activation of innate immune response GO:0002218 16 11 0,000 0,0478313 0,08479816 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0478313 0,08473667 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0478313 0,08467526 ! lysogeny GO:0030069 22 11 0,000 0,0478313 0,08461395 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0478313 0,08455272 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0478313 0,08449159 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0478313 0,08443054 ! regulation of embryonic development GO:0045995 35 11 0,000 0,0478313 0,08436958 ! nucleus localization GO:0051647 22 11 0,000 0,0478313 0,08430871 ! blood coagulation GO:0007596 151 79 1,000 0,04842234 0,08528895 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,04842234 0,0852275 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,04842234 0,08516614 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,04952259 0,08703862 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,04952259 0,08697604 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,04952259 0,08691356 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,05063186 0,08879658 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,05063186 0,08873288 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,05175006 0,09062753 ! protein import into nucleus GO:0006606 174 82 1,000 0,05175006 0,09056261 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05206519 0,09104885 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,05206519 0,09098373 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05206519 0,09091869 ! virus-host interaction GO:0019048 30 12 0,000 0,05206519 0,09085375 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05206519 0,0907889 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05206519 0,09072414 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05206519 0,09065948 ! protein complex disassembly GO:0043241 28 12 0,000 0,05206519 0,09059491 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05206519 0,09053043 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05206519 0,09046604 ! hippocampus development GO:0021766 29 12 0,000 0,05206519 0,09040174 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05206519 0,09033753 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05206519 0,09027342 ! T cell proliferation GO:0042098 32 12 0,000 0,05206519 0,0902094 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05206519 0,09014546 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05206519 0,09008162 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05206519 0,09001787 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05206519 0,08995421 ! drug transport GO:0015893 16 12 0,000 0,05206519 0,08989063 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05206519 0,08982715 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05206519 0,08976376 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05206519 0,08970046 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05206519 0,08963724 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05206519 0,08957412 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05206519 0,08951108 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05206519 0,08944813 ! lipid digestion GO:0044241 21 12 0,000 0,05206519 0,08938528 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05206519 0,08932251 ! entry into host cell GO:0030260 34 12 0,000 0,05206519 0,08925982 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05206519 0,08919723 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05206519 0,08913472 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05206519 0,0890723 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05206519 0,08900997 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05206519 0,08894773 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05206519 0,08888557 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05206519 0,0888235 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05206519 0,08876151 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05206519 0,08869961 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05206519 0,0886378 ! cranial nerve development GO:0021545 23 12 0,000 0,05206519 0,08857608 ! fucose catabolic process GO:0019317 25 12 0,000 0,05206519 0,08851444 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 27 12 0,000 0,05206519 0,08845288 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05206519 0,08839142 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05206519 0,08833003 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05206519 0,08826874 ! zymogen activation GO:0031638 18 12 0,000 0,05206519 0,08820752 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05206519 0,08814639 ! T cell homeostasis GO:0043029 28 12 0,000 0,05206519 0,08808535 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05206519 0,08802439 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05206519 0,08796352 ! oocyte differentiation GO:0009994 21 12 0,000 0,05206519 0,08790273 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05206519 0,08784202 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05206519 0,0877814 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05206519 0,08772086 ! defense response to fungus GO:0050832 15 12 0,000 0,05206519 0,08766041 ! developmental induction GO:0031128 22 12 0,000 0,05206519 0,08760003 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05206519 0,08753974 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05206519 0,08747954 ! response to cold GO:0009409 17 12 0,000 0,05206519 0,08741941 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05206519 0,08735937 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05206519 0,08729942 ! localization within membrane GO:0051668 26 12 0,000 0,05206519 0,08723954 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,05287709 0,08853922 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,05287709 0,08847858 ! hemostasis GO:0007599 165 85 1,000 0,05515722 0,09223072 ! negative regulation of transport GO:0051051 164 85 1,000 0,05515722 0,09216764 ! negative regulation of growth GO:0045926 168 85 1,000 0,05515722 0,09210464 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,05515722 0,09204172 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,05515722 0,0919789 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,05515722 0,09191616 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05628036 0,09372388 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05628036 0,09366003 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05628036 0,09359627 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05628036 0,0935326 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05628036 0,09346902 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 28 13 0,000 0,05628036 0,09340552 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05628036 0,09334211 ! cartilage condensation GO:0001502 22 13 0,000 0,05628036 0,09327878 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05628036 0,09321554 ! organelle fusion GO:0048284 36 13 0,000 0,05628036 0,09315239 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05628036 0,09308932 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05628036 0,09302634 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05628036 0,09296344 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05628036 0,09290063 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05628036 0,0928379 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05628036 0,09277525 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05628036 0,0927127 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05628036 0,09265022 ! methionine metabolic process GO:0006555 31 13 0,000 0,05628036 0,09258783 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05628036 0,09252552 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05628036 0,0924633 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05628036 0,09240116 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05628036 0,09233911 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05628036 0,09227713 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05628036 0,09221524 ! exocrine system development GO:0035272 34 13 0,000 0,05628036 0,09215344 ! monoamine transport GO:0015844 21 13 0,000 0,05628036 0,09209171 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,05628036 0,09203007 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,05628036 0,09196851 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05628036 0,09190704 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05628036 0,09184564 ! protein homotetramerization GO:0051289 24 13 0,000 0,05628036 0,09178433 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05628036 0,0917231 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05628036 0,09166195 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05628036 0,09160088 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05628036 0,0915399 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05628036 0,09147899 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05628036 0,09141817 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,05628036 0,09135743 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05628036 0,09129676 ! histone methylation GO:0016571 29 13 0,000 0,05628036 0,09123618 ! chromatin silencing GO:0006342 29 13 0,000 0,05628036 0,09117568 ! gland morphogenesis GO:0022612 31 13 0,000 0,05628036 0,09111526 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05628036 0,09105492 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05628036 0,09099466 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05628036 0,09093448 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05628036 0,09087437 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05628036 0,09081435 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05628036 0,09075441 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05628036 0,09069454 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05628036 0,09063476 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05628036 0,09057505 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05628036 0,09051542 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05628036 0,09045587 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05628036 0,0903964 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05628036 0,09033701 ! insulin secretion GO:0030073 24 13 0,000 0,05628036 0,09027769 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05628036 0,09021846 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05628036 0,0901593 ! acrosome reaction GO:0007340 19 13 0,000 0,05628036 0,09010021 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05628036 0,09004121 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05628036 0,08998228 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,05631013 0,08997099 GO:0002696|positive regulation of leukocyte activation, ! alcohol catabolic process GO:0046164 142 87 1,000 0,05747146 0,09176653 ! regulation of neurological system process GO:0031644 175 89 1,000 0,05981905 0,09545261 ! protein localization in nucleus GO:0034504 192 89 1,000 0,05981905 0,0953903 ! rRNA transcription GO:0009303 28 14 0,000 0,06047692 0,09637645 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06047692 0,09631363 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06047692 0,09625088 ! water transport GO:0006833 21 14 0,000 0,06047692 0,09618822 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06047692 0,09612564 ! non-recombinational repair GO:0000726 29 14 0,000 0,06047692 0,09606314 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06047692 0,09600072 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06047692 0,09593838 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06047692 0,09587612 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06047692 0,09581395 ! lipid localization GO:0010876 32 14 0,000 0,06047692 0,09575185 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06047692 0,09568983 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,06047692 0,0956279 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06047692 0,09556604 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06047692 0,09550427 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06047692 0,09544257 ! arginine metabolic process GO:0006525 21 14 0,000 0,06047692 0,09538096 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06047692 0,09531942 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06047692 0,09525797 ! regulation of heart rate GO:0002027 25 14 0,000 0,06047692 0,09519659 ! fear response GO:0042596 34 14 0,000 0,06047692 0,09513529 ! organic alcohol transport GO:0015850 29 14 0,000 0,06047692 0,09507407 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06047692 0,09501293 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06047692 0,09495187 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06047692 0,09489088 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06047692 0,09482998 ! bone mineralization GO:0030282 18 14 0,000 0,06047692 0,09476915 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06047692 0,0947084 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06047692 0,09464773 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06047692 0,09458714 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06047692 0,09452662 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06047692 0,09446618 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06047692 0,09440582 ! ribosome assembly GO:0042255 18 14 0,000 0,06047692 0,09434553 ! cerebellum development GO:0021549 23 14 0,000 0,06047692 0,09428533 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06047692 0,09422519 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06047692 0,09416514 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06047692 0,09410516 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06047692 0,09404526 ! oxygen transport GO:0015671 22 14 0,000 0,06047692 0,09398544 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06047692 0,09392569 ! male genitalia development GO:0030539 26 14 0,000 0,06047692 0,09386601 ! regulation of RNA stability GO:0043487 33 14 0,000 0,06047692 0,09380642 ! regulation of axon extension GO:0030516 43 14 0,000 0,06047692 0,09374689 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06047692 0,09368745 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06047692 0,09362808 ! response to unfolded protein GO:0006986 139 90 1,000 0,06100511 0,09438599 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,06100511 0,09432625 ! gland development GO:0048732 220 91 1,000 0,06219922 0,09611175 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,0646112 0,0997757 ! vitamin metabolic process GO:0006766 153 93 1,000 0,0646112 0,09971267 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06465492 0,09971716 ! lactation GO:0007595 30 15 0,000 0,06465492 0,09965425 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,06465492 0,09959141 ! reproductive cellular process GO:0048610 22 15 0,000 0,06465492 0,09952866 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06465492 0,09946598 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06465492 0,09940339 ! superoxide anion generation GO:0042554 22 15 0,000 0,06465492 0,09934087 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,06465492 0,09927843 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06465492 0,09921607 ! copper ion transport GO:0006825 22 15 0,000 0,06465492 0,09915379 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06465492 0,09909158 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06465492 0,09902945 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06465492 0,09896741 ! sulfate transport GO:0008272 27 15 0,000 0,06465492 0,09890544 ! response to cAMP GO:0051591 25 15 0,000 0,06465492 0,09884354 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06465492 0,09878173 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06465492 0,09871999 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06465492 0,09865833 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06465492 0,09859674 ! vesicle coating GO:0006901 38 15 0,000 0,06465492 0,09853523 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,06465492 0,0984738 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06465492 0,09841245 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06465492 0,09835117 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06465492 0,09828997 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06465492 0,09822884 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06465492 0,09816779 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06465492 0,09810682 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06465492 0,09804592 ! histone deacetylation GO:0016575 24 15 0,000 0,06465492 0,0979851 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06465492 0,09792435 ! water homeostasis GO:0030104 28 15 0,000 0,06465492 0,09786368 ! cofactor transport GO:0051181 30 15 0,000 0,06465492 0,09780308 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06465492 0,09774256 ! muscle maintenance GO:0046716 26 15 0,000 0,06465492 0,09768212 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06465492 0,09762174 ! intestinal absorption GO:0050892 31 15 0,000 0,06465492 0,09756145 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06465492 0,09750122 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06465492 0,09744107 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06465492 0,097381 ! cell killing GO:0001906 32 15 0,000 0,06465492 0,097321 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06465492 0,09726107 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,06465492 0,09720122 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06465492 0,09714144 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06465492 0,09708173 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06465492 0,0970221 ! actin filament polymerization GO:0030041 27 15 0,000 0,06465492 0,09696254 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06465492 0,09690306 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,06582889 0,09860207 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,06582889 0,09854166 ! regulation of membrane potential GO:0042391 179 94 1,000 0,06582889 0,09848131 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,06705426 0,1002531 ! sex differentiation GO:0007548 171 96 1,000 0,06828722 0,10203405 ! response to protein stimulus GO:0051789 158 96 1,000 0,06828722 0,10197168 ! regulation of T cell activation GO:0050863 175 96 1,000 0,06828722 0,10190939 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06881447 0,10263355 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06881447 0,10257093 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06881447 0,10250839 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06881447 0,10244592 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06881447 0,10238353 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06881447 0,10232121 ! bone remodeling GO:0046849 28 16 0,000 0,06881447 0,10225897 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06881447 0,10219681 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06881447 0,10213472 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06881447 0,10207271 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06881447 0,10201077 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06881447 0,10194891 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06881447 0,10188712 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06881447 0,10182541 ! startle response GO:0001964 28 16 0,000 0,06881447 0,10176377 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06881447 0,10170221 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06881447 0,10164072 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06881447 0,10157931 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06881447 0,10151797 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06881447 0,1014567 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06881447 0,10139551 ! pituitary gland development GO:0021983 30 16 0,000 0,06881447 0,10133439 ! response to osmotic stress GO:0006970 27 16 0,000 0,06881447 0,10127334 ! lysosomal transport GO:0007041 31 16 0,000 0,06881447 0,10121237 ! fructose metabolic process GO:0006000 25 16 0,000 0,06881447 0,10115148 ! L-amino acid transport GO:0015807 33 16 0,000 0,06881447 0,10109065 ! stem cell development GO:0048864 46 16 0,000 0,06881447 0,1010299 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06881447 0,10096922 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06881447 0,10090861 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06881447 0,10084808 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06881447 0,10078762 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06881447 0,10072723 ! axon cargo transport GO:0008088 46 16 0,000 0,06881447 0,10066692 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06881447 0,10060667 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06881447 0,1005465 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06881447 0,1004864 ! DNA replication initiation GO:0006270 28 16 0,000 0,06881447 0,10042638 ! tissue regeneration GO:0042246 27 16 0,000 0,06881447 0,10036642 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06881447 0,10030653 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06881447 0,10024672 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06881447 0,10018698 ! biomineral formation GO:0031214 22 16 0,000 0,06881447 0,10012731 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06881447 0,10006771 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06881447 0,10000818 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06881447 0,09994872 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06881447 0,09988934 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06881447 0,09983002 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06881447 0,09977077 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06881447 0,0997116 ! peptide hormone processing GO:0016486 27 16 0,000 0,06881447 0,09965249 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,07077553 0,10243164 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,07295564 0,10552434 ! metencephalon development GO:0022037 32 17 0,000 0,07295564 0,1054619 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07295564 0,10539954 ! signal complex assembly GO:0007172 47 17 0,000 0,07295564 0,10533724 ! filopodium assembly GO:0046847 42 17 0,000 0,07295564 0,10527503 ! endothelial cell migration GO:0043542 31 17 0,000 0,07295564 0,10521288 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07295564 0,10515081 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07295564 0,10508881 ! glial cell development GO:0021782 28 17 0,000 0,07295564 0,10502688 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,07295564 0,10496503 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07295564 0,10490325 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07295564 0,10484154 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07295564 0,1047799 ! myoblast differentiation GO:0045445 50 17 0,000 0,07295564 0,10471834 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,07295564 0,10465685 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,07295564 0,10459543 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,07295564 0,10453409 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,07295564 0,10447281 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,07295564 0,10441161 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,07295564 0,10435048 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,07295564 0,10428942 ! membrane budding GO:0006900 42 17 0,000 0,07295564 0,10422843 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07295564 0,10416751 ! regulation of protein binding GO:0043393 33 17 0,000 0,07295564 0,10410667 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07295564 0,10404589 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07295564 0,10398519 ! genitalia development GO:0048806 32 17 0,000 0,07295564 0,10392456 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07295564 0,103864 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,07295564 0,10380351 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07295564 0,10374308 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,07295564 0,10368273 ! steroid catabolic process GO:0006706 34 17 0,000 0,07295564 0,10362245 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,07295564 0,10356224 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07295564 0,1035021 ! gas transport GO:0015669 26 17 0,000 0,07295564 0,10344203 ! organic cation transport GO:0015695 32 17 0,000 0,07295564 0,10338203 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,07295564 0,1033221 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07295564 0,10326224 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,07295564 0,10320244 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,0732931 0,10361981 GO:0060538|skeletal muscle organ development, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,0770785 0,10890849 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0770785 0,10884554 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0770785 0,10878266 ! limbic system development GO:0021761 40 18 0,000 0,0770785 0,10871985 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0770785 0,10865711 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0770785 0,10859445 ! adult walking behavior GO:0007628 36 18 0,000 0,0770785 0,10853186 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0770785 0,10846934 ! heart looping GO:0001947 34 18 0,000 0,0770785 0,10840689 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0770785 0,10834452 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0770785 0,10828222 ! centrosome cycle GO:0007098 26 18 0,000 0,0770785 0,10821999 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0770785 0,10815783 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0770785 0,10809574 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,0770785 0,10803372 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0770785 0,10797178 ! response to retinoic acid GO:0032526 31 18 0,000 0,0770785 0,1079099 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,0770785 0,1078481 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0770785 0,10778636 ! DNA integration GO:0015074 32 18 0,000 0,0770785 0,1077247 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0770785 0,10766311 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0770785 0,10760159 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0770785 0,10754013 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0770785 0,10747875 ! neural crest cell migration GO:0001755 41 18 0,000 0,0770785 0,10741744 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0770785 0,1073562 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0770785 0,10729503 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0770785 0,10723393 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0770785 0,10717289 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0770785 0,10711193 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0770785 0,10705104 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,0770785 0,10699021 ! detection of bacterium GO:0016045 22 18 0,000 0,0770785 0,10692946 ! nerve development GO:0021675 34 18 0,000 0,0770785 0,10686877 ! defense response to virus GO:0051607 43 18 0,000 0,0770785 0,10680815 ! microspike assembly GO:0030035 46 18 0,000 0,0770785 0,10674761 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0770785 0,10668713 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0770785 0,10662671 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08118314 0,11224133 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08118314 0,11217784 ! neuron maturation GO:0042551 46 19 0,000 0,08118314 0,11211443 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,08118314 0,11205109 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08118314 0,11198782 GO:0019692|deoxyribose phosphate metabolic process, ! inositol metabolic process GO:0006020 33 19 0,000 0,08118314 0,11192462 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08118314 0,11186149 ! memory GO:0007613 34 19 0,000 0,08118314 0,11179843 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08118314 0,11173545 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08118314 0,11167254 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08118314 0,11160969 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08118314 0,11154692 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,08118314 0,11148422 ! cerebral cortex development GO:0021987 40 19 0,000 0,08118314 0,11142159 ! pigmentation during development GO:0048066 42 19 0,000 0,08118314 0,11135902 ! response to vitamin A GO:0033189 32 19 0,000 0,08118314 0,11129653 ! heme metabolic process GO:0042168 40 19 0,000 0,08118314 0,11123411 ! response to fungus GO:0009620 26 19 0,000 0,08118314 0,11117176 ! protein export from nucleus GO:0006611 40 19 0,000 0,08118314 0,11110948 ! heart process GO:0003015 32 19 0,000 0,08118314 0,11104727 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,08118314 0,11098513 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08118314 0,11092306 ! visual learning GO:0008542 38 19 0,000 0,08118314 0,11086105 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,08118314 0,11079912 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08118314 0,11073725 ! vitamin transport GO:0051180 31 19 0,000 0,08118314 0,11067546 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08118314 0,11061373 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08118314 0,11055207 ! cilium assembly GO:0042384 38 19 0,000 0,08118314 0,11049049 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08118314 0,11042897 ! protein secretion GO:0009306 45 20 0,000 0,08526965 0,11592307 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08526965 0,11585859 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08526965 0,11579419 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08526965 0,11572986 ! skin development GO:0043588 42 20 0,000 0,08526965 0,1156656 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,08526965 0,11560142 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08526965 0,1155373 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08526965 0,11547326 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,08526965 0,11540928 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,08526965 0,11534538 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08526965 0,11528155 ! response to vitamin GO:0033273 36 20 0,000 0,08526965 0,11521778 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08526965 0,11515409 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,08526965 0,11509047 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,08526965 0,11502692 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08526965 0,11496344 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,08526965 0,11490003 ! body fluid secretion GO:0007589 33 20 0,000 0,08526965 0,11483669 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08526965 0,11477342 ! peptide secretion GO:0002790 38 20 0,000 0,08526965 0,11471022 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08526965 0,11464708 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08526965 0,11458402 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08526965 0,11452103 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08526965 0,11445811 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08526965 0,11439525 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08526965 0,11433247 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,08526965 0,11426975 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08526965 0,1142071 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08526965 0,11414452 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08526965 0,11408201 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08526965 0,11401957 ! regulation of glucose import GO:0046324 30 20 0,000 0,08526965 0,11395719 GO:0010827|regulation of glucose transport, ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08526965 0,11389489 ! negative regulation of translation GO:0017148 32 20 0,000 0,08526965 0,11383265 ! regulation of cell killing GO:0031341 46 21 0,000 0,08933809 0,11919878 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08933809 0,11913371 ! hormone secretion GO:0046879 39 21 0,000 0,08933809 0,11906872 ! lipid phosphorylation GO:0046834 43 21 0,000 0,08933809 0,1190038 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08933809 0,11893894 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08933809 0,11887416 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08933809 0,11880945 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08933809 0,11874481 ! ovarian follicle development GO:0001541 39 21 0,000 0,08933809 0,11868024 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08933809 0,11861574 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,08933809 0,11855131 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08933809 0,11848695 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08933809 0,11842266 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08933809 0,11835844 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08933809 0,11829429 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08933809 0,11823021 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08933809 0,11816619 ! sensory perception of pain GO:0019233 33 21 0,000 0,08933809 0,11810225 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08933809 0,11803838 ! diencephalon development GO:0021536 36 21 0,000 0,08933809 0,11797457 ! collagen fibril organization GO:0030199 62 21 0,000 0,08933809 0,11791084 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08933809 0,11784717 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08933809 0,11778357 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08933809 0,11772004 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08933809 0,11765658 ! collagen catabolic process GO:0030574 29 21 0,000 0,08933809 0,11759319 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08933809 0,11752987 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08933809 0,11746661 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08933809 0,11740342 ! actin filament-based movement GO:0030048 47 21 0,000 0,08933809 0,1173403 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,09338856 0,12259443 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09338856 0,12252859 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09338856 0,12246282 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09338856 0,12239712 ! microtubule-based transport GO:0010970 59 22 0,000 0,09338856 0,1223315 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,09338856 0,12226594 ! vacuolar transport GO:0007034 41 22 0,000 0,09338856 0,12220045 ! central nervous system neuron development GO:0021954 47 22 0,000 0,09338856 0,12213503 ! fucose metabolic process GO:0006004 44 22 0,000 0,09338856 0,12206968 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09338856 0,12200441 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09338856 0,1219392 ! ureteric bud development GO:0001657 50 22 0,000 0,09338856 0,12187406 ! stem cell differentiation GO:0048863 57 22 0,000 0,09338856 0,12180899 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,09338856 0,12174399 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09338856 0,12167906 ! cytolysis GO:0019835 27 22 0,000 0,09338856 0,1216142 ! renal system process GO:0003014 42 22 0,000 0,09338856 0,12154941 ! vasodilation GO:0042311 40 22 0,000 0,09338856 0,12148469 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09338856 0,12142003 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,09338856 0,12135545 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,09338856 0,12129093 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09338856 0,12122648 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,09338856 0,1211621 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09338856 0,12109779 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09338856 0,12103355 ! sarcomere organization GO:0045214 32 22 0,000 0,09338856 0,12096937 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,09338856 0,12090527 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09338856 0,12084123 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09338856 0,12077726 ! gut development GO:0048565 44 22 0,000 0,09338856 0,12071335 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09338856 0,12064952 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,09338856 0,12058575 ! protein stabilization GO:0050821 41 22 0,000 0,09338856 0,12052205 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,09742112 0,12565987 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09742112 0,12559355 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09742112 0,12552731 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09742112 0,12546114 ! viral genome replication GO:0019079 44 23 0,000 0,09742112 0,12539504 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,09742112 0,12532901 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09742112 0,12526304 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09742112 0,12519715 ! regeneration GO:0031099 42 23 0,000 0,09742112 0,12513133 ! axis specification GO:0009798 43 23 0,000 0,09742112 0,12506557 ! visual behavior GO:0007632 46 23 0,000 0,09742112 0,12499989 ! response to ethanol GO:0045471 47 23 0,000 0,09742112 0,12493427 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09742112 0,12486872 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09742112 0,12480324 ! peroxisome organization GO:0007031 43 23 0,000 0,09742112 0,12473783 ! lysosome organization GO:0007040 47 23 0,000 0,09742112 0,12467249 ! vesicle targeting GO:0006903 49 23 0,000 0,09742112 0,12460722 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09742112 0,12454201 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09742112 0,12447688 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,09742112 0,12441181 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09742112 0,12434681 ! fatty acid transport GO:0015908 47 23 0,000 0,09742112 0,12428187 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,09742112 0,12421701 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09742112 0,12415221 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09742112 0,12408748 ! hormone transport GO:0009914 41 23 0,000 0,09742112 0,12402282 ! cell-cell recognition GO:0009988 28 23 0,000 0,09742112 0,12395822 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09742112 0,12389369 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10143585 0,12893225 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,10143585 0,1288652 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10143585 0,12879823 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10143585 0,12873132 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10143585 0,12866448 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10143585 0,12859771 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,10143585 0,12853101 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,10143585 0,12846438 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,10143585 0,12839782 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,10143585 0,12833132 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10143585 0,1282649 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,10143585 0,12819854 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10143585 0,12813226 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10143585 0,12806604 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10143585 0,12799989 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,10143585 0,12793381 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,10143585 0,1278678 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10143585 0,12780185 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10143585 0,12773597 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,10143585 0,12767016 ! membrane depolarization GO:0051899 45 24 0,000 0,10143585 0,12760442 ! pallium development GO:0021543 56 24 0,000 0,10143585 0,12753875 ! oogenesis GO:0048477 44 24 0,000 0,10143585 0,12747314 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,10143585 0,1274076 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,10143585 0,12734213 ! platelet activation GO:0030168 41 24 0,000 0,10143585 0,12727673 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10143585 0,12721139 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10143585 0,12714612 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10143585 0,12708092 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10143585 0,12701578 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,10143585 0,12695071 ! regulation of amine transport GO:0051952 41 24 0,000 0,10143585 0,12688571 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,10143585 0,12682077 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,10543284 0,13175061 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,10543284 0,13168325 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10543284 0,13161596 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10543284 0,13154874 ! keratinization GO:0031424 37 25 0,000 0,10543284 0,13148159 ! vacuole organization GO:0007033 49 25 0,000 0,10543284 0,13141451 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10543284 0,13134749 ! receptor metabolic process GO:0043112 53 25 0,000 0,10543284 0,13128055 ! chromosome condensation GO:0030261 48 25 0,000 0,10543284 0,13121367 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,10543284 0,13114686 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,10543284 0,13108012 ! interaction with host GO:0051701 66 25 0,000 0,10543284 0,13101345 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,10543284 0,13094684 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10543284 0,1308803 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,10543284 0,13081383 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,10543284 0,13074743 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10543284 0,13068109 ! liver development GO:0001889 55 25 0,000 0,10543284 0,13061483 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,10941217 0,13547589 ! initiation of viral infection GO:0019059 60 26 0,000 0,10941217 0,13540726 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10941217 0,1353387 ! molting cycle process GO:0022404 52 26 0,000 0,10941217 0,13527021 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10941217 0,13520178 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,10941217 0,13513343 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,10941217 0,13506515 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,10941217 0,13499693 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,10941217 0,13492879 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,10941217 0,13486071 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,10941217 0,1347927 ! digestive system process GO:0022600 49 26 0,000 0,10941217 0,13472476 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,10941217 0,13465689 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,10941217 0,13458909 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,10941217 0,13452135 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,10941217 0,13445369 ! osteoblast differentiation GO:0001649 63 26 0,000 0,10941217 0,13438609 ! neural crest cell development GO:0014032 59 26 0,000 0,10941217 0,13431856 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,10941217 0,13425109 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10941217 0,1341837 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10941217 0,13411637 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10941217 0,13404911 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10941217 0,13398192 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,10941217 0,13391479 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,10941217 0,13384773 ! blastocyst development GO:0001824 50 26 0,000 0,10941217 0,13378074 ! telomere organization GO:0032200 46 26 0,000 0,10941217 0,13371382 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10941217 0,13364696 ! neural tube closure GO:0001843 58 26 0,000 0,10941217 0,13358017 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,10941217 0,13351345 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,10941217 0,13344679 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10941217 0,1333802 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1133739 0,13814087 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1133739 0,13807201 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1133739 0,13800321 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1133739 0,13793448 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1133739 0,13786583 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1133739 0,13779724 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1133739 0,13772871 ! iron ion transport GO:0006826 65 27 0,000 0,1133739 0,13766026 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1133739 0,13759187 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1133739 0,13752356 ! tube lumen formation GO:0035148 59 27 0,000 0,1133739 0,13745531 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1133739 0,13738712 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1133739 0,13731901 ! response to toxin GO:0009636 49 27 0,000 0,1133739 0,13725096 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1133739 0,13718298 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1133739 0,13711507 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,11731812 0,14181503 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,11731812 0,14174489 ! protein amino acid acylation GO:0043543 59 28 0,000 0,11731812 0,14167483 ! vesicle docking GO:0048278 55 28 0,000 0,11731812 0,14160483 ! circadian rhythm GO:0007623 56 28 0,000 0,11731812 0,1415349 ! dendrite development GO:0016358 67 28 0,000 0,11731812 0,14146504 ! fat cell differentiation GO:0045444 57 28 0,000 0,11731812 0,14139525 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11731812 0,14132553 ! sperm motility GO:0030317 37 28 0,000 0,11731812 0,14125588 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11731812 0,14118629 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11731812 0,14111678 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,11731812 0,14104733 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,11731812 0,14097795 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,11731812 0,14090864 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11731812 0,1408394 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11731812 0,14077022 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,11731812 0,14070112 ! glutathione metabolic process GO:0006749 42 28 0,000 0,11731812 0,14063208 ! lipid oxidation GO:0034440 48 28 0,000 0,11731812 0,14056311 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,11731812 0,1404942 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,11731812 0,14042537 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,12124491 0,14505451 ! translational initiation GO:0006413 66 29 0,000 0,12124491 0,14498351 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12124491 0,14491258 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,12124491 0,14484172 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,12124491 0,14477093 ! primary neural tube formation GO:0014020 61 29 0,000 0,12124491 0,1447002 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,12124491 0,14462955 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,12124491 0,14455896 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,12124491 0,14448845 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,12124491 0,144418 ! somitogenesis GO:0001756 52 29 0,000 0,12124491 0,14434762 ! synaptogenesis GO:0007416 46 29 0,000 0,12124491 0,14427731 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,12124491 0,14420707 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12124491 0,14413689 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12124491 0,14406679 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,12124491 0,14399675 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,12515434 0,14856756 ! phenol metabolic process GO:0018958 56 30 0,000 0,12515434 0,14849541 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,12515434 0,14842332 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,12515434 0,14835131 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,12515434 0,14827936 ! sensory perception of taste GO:0050909 41 30 0,000 0,12515434 0,14820749 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,12515434 0,14813568 ! acute-phase response GO:0006953 50 30 0,000 0,12515434 0,14806394 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,12515434 0,14799228 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,12515434 0,14792068 ! myofibril assembly GO:0030239 50 30 0,000 0,12515434 0,14784915 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,12515434 0,14777769 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,12515434 0,1477063 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,12515434 0,14763498 ! cell fate determination GO:0001709 64 30 0,000 0,12515434 0,14756373 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,12515434 0,14749254 ! phospholipid transport GO:0015914 65 30 0,000 0,12515434 0,14742143 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,12515434 0,14735038 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,12515434 0,14727941 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,12515434 0,1472085 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,12515434 0,14713765 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,12904648 0,15164048 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,12904648 0,15156757 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,12904648 0,15149474 ! regulation of innate immune response GO:0045088 57 31 0,000 0,12904648 0,15142198 ! ovulation cycle process GO:0022602 55 31 0,000 0,12904648 0,15134928 ! peptide transport GO:0015833 60 31 0,000 0,12904648 0,15127666 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,12904648 0,1512041 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,12904648 0,15113162 ! natural killer cell activation GO:0030101 50 31 0,000 0,12904648 0,1510592 ! cofactor catabolic process GO:0051187 54 31 0,000 0,12904648 0,15098686 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,12904648 0,15091458 ! eye morphogenesis GO:0048592 65 31 0,000 0,12904648 0,15084237 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,12904648 0,15077023 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,13292142 0,15522324 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,13292142 0,15514908 ! collagen metabolic process GO:0032963 49 32 0,000 0,13292142 0,15507499 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,13292142 0,15500097 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,13292142 0,15492702 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,13292142 0,15485314 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,13292142 0,15477933 ! muscle cell development GO:0055001 52 32 0,000 0,13292142 0,15470559 ! mesoderm formation GO:0001707 73 32 0,000 0,13292142 0,15463192 ! ovulation cycle GO:0042698 57 32 0,000 0,13292142 0,15455832 ! BMP signaling pathway GO:0030509 71 32 0,000 0,13292142 0,15448479 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,13292142 0,15441133 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,13292142 0,15433794 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,13292142 0,15426462 ! gene silencing GO:0016458 71 32 0,000 0,13292142 0,15419137 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,13677923 0,15859119 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,13677923 0,15851596 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13677923 0,1584408 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,13677923 0,15836571 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,13677923 0,15829069 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,13677923 0,15821574 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,13677923 0,15814086 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,13677923 0,15806606 GO:0060326|cell chemotaxis, ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13677923 0,15799132 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,13677923 0,15791666 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,13677923 0,15784206 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,14061998 0,16219764 ! glial cell differentiation GO:0010001 67 34 0,000 0,14061998 0,16212109 ! post-embryonic development GO:0009791 76 34 0,000 0,14061998 0,16204462 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,14061998 0,16196822 ! cholesterol transport GO:0030301 62 34 0,000 0,14061998 0,16189189 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,14061998 0,16181564 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,14061998 0,16173945 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,14061998 0,16166334 ! formation of primary germ layer GO:0001704 76 34 0,000 0,14061998 0,1615873 ! cell fate specification GO:0001708 56 34 0,000 0,14061998 0,16151133 ! adult locomotory behavior GO:0008344 62 34 0,000 0,14061998 0,16143543 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,14061998 0,16135961 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,14444374 0,16566952 ! negative regulation of secretion GO:0051048 68 35 0,000 0,14444374 0,16559177 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,14444374 0,1655141 ! membrane docking GO:0022406 69 35 0,000 0,14444374 0,16543651 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,14444374 0,16535898 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,14444374 0,16528153 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,14444374 0,16520415 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,14444374 0,16512685 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,14444374 0,16504961 ! ceramide metabolic process GO:0006672 72 35 0,000 0,14444374 0,16497245 ! telencephalon development GO:0021537 81 35 0,000 0,14444374 0,16489536 ! sterol transport GO:0015918 63 35 0,000 0,14444374 0,16481834 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,14444374 0,1647414 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,14444374 0,16466452 ! placenta development GO:0001890 53 35 0,000 0,14444374 0,16458772 ! vesicle localization GO:0051648 70 35 0,000 0,14444374 0,16451099 ! regulation of muscle development GO:0048634 82 36 0,000 0,14825061 0,16876805 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,14825061 0,16868944 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14825061 0,16861091 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,14825061 0,16853245 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,14825061 0,16845406 ! positive regulation of cell development GO:0010720 85 36 0,000 0,14825061 0,16837575 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14825061 0,16829751 ! regulation of proteolysis GO:0030162 77 36 0,000 0,14825061 0,16821934 ! aerobic respiration GO:0009060 56 36 0,000 0,14825061 0,16814124 ! cytokine production GO:0001816 68 36 0,000 0,14825061 0,16806322 ! embryonic organ development GO:0048568 67 36 0,000 0,14825061 0,16798527 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14825061 0,16790739 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,15204064 0,17212015 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,15204064 0,17204043 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,15204064 0,17196078 ! odontogenesis GO:0042476 74 37 0,000 0,15204064 0,1718812 ! actomyosin structure organization GO:0031032 68 37 0,000 0,15204064 0,1718017 ! tissue remodeling GO:0048771 78 37 0,000 0,15204064 0,17172227 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,15204064 0,17164292 ! female gonad development GO:0008585 71 37 0,000 0,15204064 0,17156364 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15204064 0,17148443 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,15204064 0,1714053 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,15204064 0,17132624 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,15581391 0,17549718 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,15581391 0,17541631 ! organic anion transport GO:0015711 82 38 0,000 0,15581391 0,17533551 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,15581391 0,17525478 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,15581391 0,17517413 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,15581391 0,17509355 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,15581391 0,17501305 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,15581391 0,17493262 ! regulation of protein stability GO:0031647 77 38 0,000 0,15581391 0,17485227 ! spermatid development GO:0007286 69 38 0,000 0,15581391 0,17477198 ! glycogen metabolic process GO:0005977 63 38 0,000 0,15581391 0,17469178 ! pigment metabolic process GO:0042440 87 38 0,000 0,15581391 0,17461164 ! neural tube formation GO:0001841 79 38 0,000 0,15581391 0,17453158 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,1595705 0,17865753 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,1595705 0,17857569 ! negative regulation of binding GO:0051100 71 39 0,000 0,1595705 0,17849392 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,1595705 0,17841223 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,1595705 0,17833062 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,1595705 0,17824907 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,1595705 0,17816761 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,1595705 0,17808622 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,1595705 0,1780049 ! glucan metabolic process GO:0044042 64 39 0,000 0,1595705 0,17792365 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,16331047 0,18201072 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,16331047 0,18192772 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,16331047 0,1818448 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,16331047 0,18176195 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,16331047 0,18167918 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,16331047 0,18159649 ! RNA export from nucleus GO:0006405 61 41 0,000 0,16703391 0,18565234 ! mRNA catabolic process GO:0006402 79 41 0,000 0,16703391 0,18556792 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,16703391 0,18548357 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,16703391 0,18539929 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,16703391 0,1853151 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,16703391 0,18523098 ! gliogenesis GO:0042063 91 41 0,000 0,16703391 0,18514694 ! feeding behavior GO:0007631 69 41 0,000 0,16703391 0,18506297 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,16703391 0,18497908 ! mesenchymal cell development GO:0014031 94 41 0,000 0,16703391 0,18489526 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,16703391 0,18481153 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,16703391 0,18472786 ! spermatid differentiation GO:0048515 73 41 0,000 0,16703391 0,18464427 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,16703391 0,18456076 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,17074088 0,18857142 ! organic ether metabolic process GO:0018904 59 42 0,000 0,17074088 0,18848621 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,17074088 0,18840108 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17074088 0,18831602 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,17074088 0,18823104 ! regulation of protein secretion GO:0050708 77 42 0,000 0,17074088 0,18814614 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,17074088 0,18806131 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,17443146 0,19203969 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,17443146 0,19195318 ! regulation of tube size GO:0035150 76 43 0,000 0,17443146 0,19186676 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,17443146 0,19178041 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,17443146 0,19169414 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,17443146 0,19160794 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,17443146 0,19152183 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,17443146 0,19143579 ! segmentation GO:0035282 78 43 0,000 0,17443146 0,19134983 ! ion transmembrane transport GO:0034220 79 43 0,000 0,17443146 0,19126394 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,17443146 0,19117814 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,17810572 0,19511761 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,17810572 0,19503016 ! striated muscle contraction GO:0006941 85 44 0,000 0,17810572 0,19494278 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,18176373 0,1988575 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,18176373 0,19876848 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,18176373 0,19867955 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,18176373 0,19859069 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,18176373 0,19850192 ! female gamete generation GO:0007292 71 45 0,000 0,18176373 0,19841322 ! polyol metabolic process GO:0019751 77 45 0,000 0,18176373 0,19832461 ! developmental growth GO:0048589 88 45 0,000 0,18176373 0,19823607 ! maintenance of location in cell GO:0051651 101 45 0,000 0,18176373 0,19814761 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,18540556 0,20202756 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,18540556 0,20193749 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,18540556 0,2018475 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,18540556 0,20175759 ! leukocyte migration GO:0050900 75 46 0,000 0,18540556 0,20166776 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,18540556 0,20157801 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,18540556 0,20148834 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,18540556 0,20139875 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,18903128 0,20524597 ! positive regulation of defense response GO:0031349 88 48 0,000 0,19264097 0,20907236 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,19264097 0,20897953 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,19264097 0,20888677 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,19264097 0,2087941 ! endosome transport GO:0016197 127 48 0,000 0,19264097 0,2087015 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,19264097 0,20860899 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,19264097 0,20851657 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,19264097 0,20842422 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,19264097 0,20833196 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,19264097 0,20823977 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,19264097 0,20814767 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,19623469 0,21193694 ! JNK cascade GO:0007254 106 49 0,000 0,19623469 0,21184328 ! regulation of ion transport GO:0043269 86 50 0,000 0,19981252 0,21561041 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,19981252 0,21551522 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,19981252 0,21542011 ! regulation of ossification GO:0030278 123 50 0,000 0,19981252 0,21532509 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,19981252 0,21523015 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,19981252 0,21513529 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,20337452 0,21887398 ! viral infectious cycle GO:0019058 104 51 0,000 0,20337452 0,21877761 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,20337452 0,21868131 ! peptide metabolic process GO:0006518 80 51 0,000 0,20337452 0,21858511 ! positive regulation of binding GO:0051099 88 52 0,000 0,20692076 0,22229878 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,20692076 0,22220106 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,20692076 0,22210344 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,20692076 0,22200589 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,20692076 0,22190844 ! excretion GO:0007588 87 52 0,000 0,20692076 0,22181107 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,20692076 0,22171378 ! histone modification GO:0016570 104 52 0,000 0,20692076 0,22161658 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,20692076 0,22151946 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,20692076 0,22142243 ! amino acid activation GO:0043038 98 52 0,000 0,20692076 0,22132549 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,21045132 0,22500331 ! positive regulation of growth GO:0045927 96 53 0,000 0,21045132 0,22490489 ! inner ear development GO:0048839 89 53 0,000 0,21045132 0,22480654 ! chromatin remodeling GO:0006338 122 53 0,000 0,21045132 0,22470829 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,21045132 0,22461012 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,21045132 0,22451204 ! cartilage development GO:0051216 99 53 0,000 0,21045132 0,22441404 ! regulation of translational initiation GO:0006446 87 54 0,000 0,21396626 0,22806264 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,21396626 0,22796318 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,21396626 0,2278638 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,21396626 0,22776452 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,21396626 0,22766532 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,21396626 0,2275662 ! membrane fusion GO:0006944 122 54 0,000 0,21396626 0,22746717 ! covalent chromatin modification GO:0016569 115 54 0,000 0,21396626 0,22736823 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,21396626 0,22726938 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,21396626 0,22717061 ! RNA catabolic process GO:0006401 103 55 0,000 0,21746565 0,23078565 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,21746565 0,23068544 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,21746565 0,23058532 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,21746565 0,23048528 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,21746565 0,23038533 ! cell maturation GO:0048469 107 55 0,000 0,21746565 0,23028547 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,21746565 0,23018569 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,22094955 0,23377209 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,22094955 0,23367089 ! RNA elongation GO:0006354 90 56 0,000 0,22094955 0,23356978 ! chloride transport GO:0006821 102 57 0,000 0,22441805 0,23713378 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,22441805 0,23703126 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,22441805 0,23692882 ! heart morphogenesis GO:0003007 105 57 0,000 0,22441805 0,23682648 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,22441805 0,23672422 ! regulation of actin filament length GO:0030832 118 58 0,000 0,2278712 0,24026299 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,2278712 0,24015934 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,2278712 0,24005577 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,2278712 0,2399523 ! gastrulation GO:0007369 122 58 0,000 0,2278712 0,23984892 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,2278712 0,23974563 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,2278712 0,23964242 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,2278712 0,2395393 ! maintenance of location GO:0051235 124 58 0,000 0,2278712 0,23943628 ! nuclear export GO:0051168 110 59 0,000 0,23130907 0,24294414 ! lipid modification GO:0030258 112 60 0,000 0,23473173 0,24643302 ! regulation of endocytosis GO:0030100 104 60 0,000 0,23473173 0,24632716 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,23473173 0,24622139 ! adult behavior GO:0030534 104 60 0,000 0,23473173 0,24611572 ! positive regulation of secretion GO:0051047 110 61 0,000 0,23813925 0,24958138 ! regulation of cellular component size GO:0032535 125 61 0,000 0,23813925 0,24947436 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,23813925 0,24936742 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,23813925 0,24926058 ! regulation of heart contraction GO:0008016 123 61 0,000 0,23813925 0,24915383 ! proton transport GO:0015992 117 61 0,000 0,23813925 0,24904717 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,23813925 0,24894061 ! viral reproductive process GO:0022415 132 62 0,000 0,24153169 0,25237893 ! tRNA processing GO:0008033 102 62 0,000 0,24153169 0,25227103 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,24490913 0,25568931 ! mesoderm development GO:0007498 128 63 0,000 0,24490913 0,25558009 ! hydrogen transport GO:0006818 121 64 0,000 0,24827161 0,25897846 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,24827161 0,25886792 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,24827161 0,25875749 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,25161922 0,26213465 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,25161922 0,26202291 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,25161922 0,26191127 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,25161922 0,26179972 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,25495201 0,26515443 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,25495201 0,2650416 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,25827006 0,26837675 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,26157342 0,27169382 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,26157342 0,27157835 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,26157342 0,27146298 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,26157342 0,27134771 ! viral reproduction GO:0016032 142 68 0,000 0,26157342 0,27123254 ! regulation of lipase activity GO:0060191 137 68 0,000 0,26157342 0,27111746 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,26157342 0,27100248 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,26486216 0,27429345 ! lung development GO:0030324 165 69 0,000 0,26486216 0,27417723 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,26486216 0,2740611 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,26486216 0,27394507 ! single fertilization GO:0007338 83 69 0,000 0,26486216 0,27382914 ! cell redox homeostasis GO:0045454 114 70 0,000 0,26813634 0,27709691 ! activation of immune response GO:0002253 120 70 0,000 0,26813634 0,27697974 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,27139604 0,28022846 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,27139604 0,28011007 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,27139604 0,27999178 ! respiratory tube development GO:0030323 171 72 0,000 0,27464131 0,28322023 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,27464131 0,28310073 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,27464131 0,28298132 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,27464131 0,28286202 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,27464131 0,28274282 ! humoral immune response GO:0006959 115 73 0,000 0,27787221 0,28594853 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,27787221 0,28582814 ! regulation of immune effector process GO:0002697 156 73 0,000 0,27787221 0,28570784 ! acute inflammatory response GO:0002526 118 74 0,000 0,28108882 0,28889356 ! amino acid transport GO:0006865 148 74 0,000 0,28108882 0,28877207 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,28108882 0,28865069 ! respiratory system development GO:0060541 175 74 0,000 0,28108882 0,28852941 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,28429119 0,29169398 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,28429119 0,29157152 ! rhythmic process GO:0048511 142 75 0,000 0,28429119 0,29144917 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,28747938 0,29459401 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,28747938 0,29447049 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,29065346 0,29759698 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,29065346 0,29747231 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,29065346 0,29734774 ! regulation of catabolic process GO:0009894 173 77 0,000 0,29065346 0,29722327 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,29381349 0,30032902 ! antigen processing and presentation GO:0019882 117 78 0,000 0,29381349 0,30020341 ! fertilization GO:0009566 99 78 0,000 0,29381349 0,30007791 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,29381349 0,29995251 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,29695953 0,30303765 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,29695953 0,30291112 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,29695953 0,30278469 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,30009164 0,3058506 ! muscle cell differentiation GO:0042692 178 81 0,000 0,30320989 0,30889982 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,30940503 0,31507982 ! exocytosis GO:0006887 153 83 0,000 0,30940503 0,31494854 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,30940503 0,31481736 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,30940503 0,3146863 ! inorganic anion transport GO:0015698 156 83 0,000 0,30940503 0,31455534 ! response to nutrient GO:0007584 135 84 0,000 0,31248204 0,31755143 ! digestion GO:0007586 130 84 0,000 0,31248204 0,31741939 ! regulation of ligase activity GO:0051340 147 84 0,000 0,31248204 0,31728746 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,31554543 0,32026485 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,31554543 0,32013185 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,31859526 0,32309183 ! regulation of lyase activity GO:0051339 169 86 0,000 0,31859526 0,32295777 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,32163158 0,32590044 ! nucleosome assembly GO:0006334 126 87 0,000 0,32163158 0,32576532 ! regulation of protein transport GO:0051223 165 87 0,000 0,32163158 0,32563032 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,32465446 0,32855462 ! sensory perception of smell GO:0007608 117 88 0,000 0,32465446 0,32841857 ! chromatin assembly GO:0031497 128 88 0,000 0,32465446 0,32828264 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,32766396 0,33118868 ! regulation of DNA binding GO:0051101 167 89 0,000 0,32766396 0,33105171 ! tube morphogenesis GO:0035239 194 89 0,000 0,32766396 0,33091486 ! cellular defense response GO:0006968 123 89 0,000 0,32766396 0,33077812 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,33066012 0,33366488 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,33066012 0,33352712 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,33364302 0,33639699 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,33364302 0,33625821 ! defense response to bacterium GO:0042742 112 91 0,000 0,33364302 0,33611955 ! bone development GO:0060348 206 92 0,000 0,33661271 0,3389715 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,33661271 0,33883183 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,33956925 0,34166708 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,33956925 0,34152642 ! female pregnancy GO:0007565 166 94 0,000 0,3425127 0,34434507 ! sterol metabolic process GO:0016125 166 94 0,000 0,3425127 0,34420342 ! regulation of defense response GO:0031347 171 95 0,000 0,3454431 0,34700555 ! nucleosome organization GO:0034728 143 95 0,000 0,3454431 0,34686293 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,3454431 0,34672042 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,3454431 0,34657803 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,3454431 0,34643576 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,35126504 0,35212987 ! regulation of protein localization GO:0032880 188 97 0,000 0,35126504 0,35198544 ! forebrain development GO:0030900 210 98 0,000 0,35415669 0,35473751 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,35415669 0,35459213 ! mRNA transport GO:0051028 185 100 0,000 0,35990161 0,36019649 ! positive regulation of immune response GO:0050778 175 100 0,000 0,35990161 0,36004899 ! hormone metabolic process GO:0042445 171 100 0,000 0,35990161 0,35990161