pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6220-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 4,000 1,139E-12 2,741E-09 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 8,783E-10 1,057E-06 ! organ growth GO:0035265 15 7 3,000 8,783E-10 7,044E-07 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 8,783E-10 5,283E-07 GO:0046676|negative regulation of insulin secretion, ! nucleosome disassembly GO:0006337 14 8 3,000 1,754E-09 8,438E-07 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! regulation of growth hormone secretion GO:0060123 16 8 3,000 1,754E-09 7,032E-07 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 1,964E-09 6,751E-07 ! regulation of histone modification GO:0031056 12 9 3,000 3,151E-09 9,476E-07 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 3,151E-09 8,423E-07 ! regulation of chromosome organization GO:0033044 42 27 4,000 4,227E-09 1,017E-06 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 5,242E-09 1,147E-06 ! activation of MAPK activity GO:0000187 115 67 5,000 1,035E-08 2,075E-06 ! DNA damage checkpoint GO:0000077 71 33 4,000 1,23E-08 2,276E-06 ! negative regulation of secretion GO:0051048 63 35 4,000 1,676E-08 2,88E-06 ! DNA integrity checkpoint GO:0031570 75 36 4,000 1,943E-08 3,116E-06 ! carbohydrate homeostasis GO:0033500 53 38 4,000 2,578E-08 3,876E-06 GO:0042593|glucose homeostasis, ! cellular response to hormone stimulus GO:0032870 167 82 5,000 3,536E-08 5,004E-06 ! regulation of intracellular protein transport GO:0033157 80 42 4,000 4,338E-08 5,798E-06 ! regulation of protein transport GO:0051223 154 87 5,000 5,053E-08 6,399E-06 GO:0070201|regulation of establishment of protein localization, ! negative regulation of hormone secretion GO:0046888 25 17 3,000 5,87E-08 7,062E-06 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 6,94E-08 7,952E-06 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 9,527E-08 1,042E-05 ! regulation of protein localization GO:0032880 176 97 5,000 9,713E-08 1,016E-05 ! cellular macromolecular complex disassembly GO:0034623 43 21 3,000 1,466E-07 1,47E-05 ! regulation of multicellular organism growth GO:0040014 85 55 4,000 1,734E-07 1,668E-05 ! regulation of intracellular transport GO:0032386 101 57 4,000 2,079E-07 1,924E-05 ! nuclear migration GO:0007097 12 6 2,000 2,29E-07 2,041E-05 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,29E-07 1,968E-05 GO:0031272|regulation of pseudopodium assembly, ! DNA damage response, signal transduction GO:0042770 128 60 4,000 2,698E-07 2,238E-05 ! regulation of insulin secretion GO:0050796 37 25 3,000 3,077E-07 2,468E-05 ! macromolecular complex disassembly GO:0032984 53 26 3,000 3,63E-07 2,818E-05 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 3,63E-07 2,73E-05 ! macrophage differentiation GO:0030225 11 7 2,000 4,002E-07 2,918E-05 ! negative regulation of protein modification process GO:0031400 60 28 3,000 4,955E-07 3,506E-05 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 4,955E-07 3,406E-05 ! cell cycle checkpoint GO:0000075 137 69 4,000 5,463E-07 3,651E-05 ! regulation of peptide secretion GO:0002791 47 29 3,000 5,738E-07 3,731E-05 ! ER overload response GO:0006983 12 8 2,000 6,392E-07 4,047E-05 ! establishment of nucleus localization GO:0040023 16 8 2,000 6,392E-07 3,944E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 6,392E-07 3,845E-05 ! triglyceride metabolic process GO:0006641 43 31 3,000 7,575E-07 4,445E-05 ! negative regulation of organelle organization GO:0010639 161 78 4,000 1,01E-06 5,786E-05 ! neutral lipid metabolic process GO:0006638 50 35 3,000 1,252E-06 7,005E-05 GO:0006639|acylglycerol metabolic process, ! androgen receptor signaling pathway GO:0030521 74 36 3,000 1,406E-06 7,688E-05 ! negative regulation of transport GO:0051051 153 84 4,000 1,461E-06 7,814E-05 ! glycerol ether metabolic process GO:0006662 53 37 3,000 1,574E-06 8,231E-05 ! nucleus localization GO:0051647 19 11 2,000 1,874E-06 9,594E-05 ! organic ether metabolic process GO:0018904 55 39 3,000 1,953E-06 9,79E-05 ! regulation of hormone secretion GO:0046883 62 40 3,000 2,166E-06 1,064E-04 ! hormone-mediated signaling GO:0009755 74 41 3,000 2,396E-06 1,153E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,495E-06 1,177E-04 ! cellular component disassembly GO:0022411 86 48 3,000 4,549E-06 2,105E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 5,134E-06 2,331E-04 ! regulation of cell projection organization GO:0031344 121 50 3,000 5,366E-06 2,391E-04 ! filopodium assembly GO:0046847 32 16 2,000 6,309E-06 2,76E-04 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 6,309E-06 2,711E-04 ! microspike assembly GO:0030035 36 17 2,000 7,648E-06 3,228E-04 ! positive regulation of secretion GO:0051047 95 59 3,000 1,044E-05 4,331E-04 ! establishment of organelle localization GO:0051656 109 59 3,000 1,044E-05 4,258E-04 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 1,357E-05 5,442E-04 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 1,357E-05 5,353E-04 ! multicellular organism reproduction GO:0032504 111 64 3,000 1,445E-05 5,608E-04 GO:0048609|reproductive process in a multicellular organism, ! cell projection assembly GO:0030031 120 66 3,000 1,633E-05 6,238E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,839E-05 6,915E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,972E-05 7,301E-04 ! protein tetramerization GO:0051262 52 24 2,000 2,25E-05 8,204E-04 ! myelination GO:0042552 45 25 2,000 2,553E-05 9,168E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 2,553E-05 9,033E-04 ! interaction with host GO:0051701 62 25 2,000 2,553E-05 8,902E-04 ! organelle localization GO:0051640 136 74 3,000 2,572E-05 8,841E-04 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,881E-05 9,764E-04 ! positive regulation of nuclear division GO:0051785 40 26 2,000 2,881E-05 9,629E-04 GO:0045840|positive regulation of mitosis, ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,236E-05 1,067E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 3,619E-05 1,177E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,03E-05 1,293E-03 ! nucleosome assembly GO:0006334 122 85 3,000 4,441E-05 1,406E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 4,47E-05 1,397E-03 GO:0008366|axon ensheathment, ! chromatin assembly GO:0031497 124 86 3,000 4,65E-05 1,434E-03 ! gland development GO:0048732 206 88 3,000 5,089E-05 1,55E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 5,15E-05 1,549E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 5,15E-05 1,53E-03 GO:0022011|myelination in the peripheral nervous system, ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 1,000 5,15E-05 1,511E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 5,15E-05 1,493E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 5,15E-05 1,475E-03 ! microvillus organization GO:0032528 7 5 1,000 5,15E-05 1,458E-03 GO:0030033|microvillus assembly, ! peripheral nervous system development GO:0007422 64 32 2,000 5,443E-05 1,523E-03 ! protein-DNA complex assembly GO:0065004 130 90 3,000 5,557E-05 1,537E-03 ! nucleosome organization GO:0034728 138 92 3,000 6,055E-05 1,656E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 6,545E-05 1,769E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 7,15E-05 1,911E-03 ! hormone metabolic process GO:0042445 157 97 3,000 7,445E-05 1,968E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 7,714E-05 2,017E-03 ! male sex determination GO:0030238 15 6 1,000 7,714E-05 1,996E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 7,714E-05 1,974E-03 GO:0051653|spindle localization, ! astrocyte development GO:0014002 15 6 1,000 7,714E-05 1,954E-03 ! Schwann cell development GO:0014044 15 6 1,000 7,714E-05 1,933E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,714E-05 1,913E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 8,457E-05 2,076E-03 ! glycogen metabolic process GO:0005977 61 37 2,000 8,457E-05 2,055E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 8,457E-05 2,035E-03 ! glucan metabolic process GO:0044042 62 38 2,000 9,167E-05 2,184E-03 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 2,000 9,914E-05 2,339E-03 ! regulation of action potential in neuron GO:0019228 73 39 2,000 9,914E-05 2,316E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 1,07E-04 2,476E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of helicase activity GO:0051095 15 7 1,000 1,078E-04 2,471E-03 ! neuron adhesion GO:0007158 12 7 1,000 1,078E-04 2,448E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,078E-04 2,425E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 1,078E-04 2,402E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,078E-04 2,38E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,078E-04 2,359E-03 ! transcription from RNA polymerase I promoter GO:0006360 13 7 1,000 1,078E-04 2,337E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,078E-04 2,316E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,078E-04 2,296E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,078E-04 2,276E-03 ! axonal fasciculation GO:0007413 18 7 1,000 1,078E-04 2,256E-03 ! energy reserve metabolic process GO:0006112 74 43 2,000 1,33E-04 2,759E-03 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,425E-04 2,93E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,436E-04 2,927E-03 ! astrocyte differentiation GO:0048708 18 8 1,000 1,436E-04 2,903E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,436E-04 2,878E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,436E-04 2,855E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,436E-04 2,831E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,628E-04 3,184E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 1,628E-04 3,159E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,843E-04 3,548E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,843E-04 3,519E-03 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,843E-04 3,492E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,843E-04 3,464E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 1,843E-04 3,438E-03 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,843E-04 3,411E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,843E-04 3,385E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,843E-04 3,359E-03 ! motor axon guidance GO:0008045 16 9 1,000 1,843E-04 3,334E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,843E-04 3,309E-03 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 1,843E-04 3,285E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,849E-04 3,271E-03 ! mitochondrial transport GO:0006839 82 48 2,000 1,849E-04 3,247E-03 ! regulation of action potential GO:0001508 95 49 2,000 1,966E-04 3,428E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 2,3E-04 3,982E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 2,3E-04 3,953E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,3E-04 3,925E-03 GO:0005978|glycogen biosynthetic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,3E-04 3,898E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,3E-04 3,87E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of growth GO:0045927 90 52 2,000 2,347E-04 3,921E-03 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,484E-04 4,121E-03 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 2,772E-04 4,569E-03 ! telencephalon cell migration GO:0022029 20 11 1,000 2,807E-04 4,595E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,807E-04 4,564E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,807E-04 4,533E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 2,807E-04 4,503E-03 ! regulation of DNA replication GO:0006275 101 56 2,000 2,924E-04 4,66E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 2,924E-04 4,629E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 3,082E-04 4,846E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,082E-04 4,815E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,364E-04 5,222E-03 ! virus-host interaction GO:0019048 29 12 1,000 3,364E-04 5,188E-03 ! forebrain cell migration GO:0021885 21 12 1,000 3,364E-04 5,155E-03 ! entry into host cell GO:0030260 32 12 1,000 3,364E-04 5,123E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 3,364E-04 5,09E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,364E-04 5,059E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,364E-04 5,027E-03 GO:0042130|negative regulation of T cell proliferation, ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,587E-04 5,327E-03 ! regulation of protein complex assembly GO:0043254 117 61 2,000 3,766E-04 5,559E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 3,766E-04 5,525E-03 ! viral reproductive process GO:0022415 126 62 2,000 3,951E-04 5,761E-03 ! response to X-ray GO:0010165 25 13 1,000 3,97E-04 5,754E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,97E-04 5,719E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,97E-04 5,685E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 3,97E-04 5,652E-03 ! regulation of mitosis GO:0007088 105 63 2,000 4,142E-04 5,862E-03 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 2,000 4,338E-04 6,104E-03 ! myeloid cell differentiation GO:0030099 111 65 2,000 4,541E-04 6,352E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,624E-04 6,431E-03 ! response to gamma radiation GO:0010332 28 14 1,000 4,624E-04 6,395E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 4,624E-04 6,358E-03 ! viral reproduction GO:0016032 134 68 2,000 5,184E-04 7,087E-03 ! pituitary gland development GO:0021983 29 15 1,000 5,328E-04 7,243E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,328E-04 7,202E-03 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,328E-04 7,162E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 5,328E-04 7,122E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,08E-04 8,082E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 6,08E-04 8,038E-03 ! activation of MAPKK activity GO:0000186 35 16 1,000 6,08E-04 7,994E-03 ! fructose metabolic process GO:0006000 25 16 1,000 6,08E-04 7,95E-03 ! neuron recognition GO:0008038 35 16 1,000 6,08E-04 7,907E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 6,08E-04 7,865E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! axon guidance GO:0007411 139 73 2,000 6,382E-04 8,211E-03 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 6,881E-04 8,806E-03 ! glial cell development GO:0021782 27 17 1,000 6,881E-04 8,759E-03 ! limbic system development GO:0021761 36 17 1,000 6,881E-04 8,713E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,881E-04 8,667E-03 ! centrosome cycle GO:0007098 25 18 1,000 7,729E-04 9,686E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 7,729E-04 9,636E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,729E-04 9,586E-03 ! protein oligomerization GO:0051259 139 78 2,000 7,742E-04 9,553E-03 ! activation of protein kinase activity GO:0032147 147 79 2,000 8,035E-04 9,863E-03 ! neuromuscular junction development GO:0007528 34 19 1,000 8,626E-04 0,01053489 ! cerebral cortex development GO:0021987 36 19 1,000 8,626E-04 0,01048168 ! regulation of neuron differentiation GO:0045664 167 81 2,000 8,641E-04 0,01044691 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,57E-04 0,0115128 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,57E-04 0,01145552 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 9,57E-04 0,01139881 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 9,57E-04 0,01134266 ! cellular response to starvation GO:0009267 33 20 1,000 9,57E-04 0,01128706 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 9,57E-04 0,011232 ! diencephalon development GO:0021536 34 20 1,000 9,57E-04 0,01117747 ! peptidyl-serine modification GO:0018209 43 20 1,000 9,57E-04 0,01112348 ! negative regulation of T cell activation GO:0050868 40 20 1,000 9,57E-04 0,01107 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,57E-04 0,01101703 ! cell aging GO:0007569 44 21 1,000 1,056E-03 0,01210081 ! glutamate signaling pathway GO:0007215 41 22 1,000 1,16E-03 0,01322822 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 1,16E-03 0,01316582 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,16E-03 0,01310401 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,16E-03 0,01304278 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,16E-03 0,01298211 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 1,16E-03 0,01292201 ! regulation of cell cycle process GO:0010564 149 90 2,000 1,172E-03 0,01299898 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,269E-03 0,01400211 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,269E-03 0,01393817 ! sex determination GO:0007530 47 23 1,000 1,269E-03 0,01387481 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,269E-03 0,01381203 ! synaptic vesicle transport GO:0048489 46 23 1,000 1,269E-03 0,01374982 ! regulation of membrane potential GO:0042391 164 93 2,000 1,289E-03 0,01390381 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,382E-03 0,0148439 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,382E-03 0,01477793 ! pallium development GO:0021543 49 24 1,000 1,382E-03 0,01471254 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,382E-03 0,01464772 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 1,455E-03 0,01535052 ! response to virus GO:0009615 160 98 2,000 1,498E-03 0,01574041 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,5E-03 0,01569054 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,5E-03 0,01562262 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,5E-03 0,01555528 ! response to starvation GO:0042594 42 25 1,000 1,5E-03 0,01548852 ! negative regulation of cell development GO:0010721 73 25 1,000 1,5E-03 0,01542233 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 1,5E-03 0,0153567 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,5E-03 0,01529163 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,542E-03 0,0156588 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 2,000 1,588E-03 0,01604906 ! initiation of viral infection GO:0019059 57 26 1,000 1,623E-03 0,01633382 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 1,623E-03 0,01626576 ! microtubule organizing center organization GO:0031023 39 26 1,000 1,623E-03 0,01619827 GO:0051297|centrosome organization, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,75E-03 0,0173961 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,75E-03 0,01732451 ! protein amino acid acylation GO:0043543 55 27 1,000 1,75E-03 0,01725351 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,75E-03 0,01718309 ! base-excision repair GO:0006284 41 27 1,000 1,75E-03 0,01711324 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 1,75E-03 0,01704396 ! regulation of pH GO:0006885 43 29 1,000 2,018E-03 0,0195772 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,018E-03 0,01949858 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 2,159E-03 0,02077704 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,159E-03 0,02069427 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 2,304E-03 0,02200114 ! spindle organization GO:0007051 46 32 1,000 2,454E-03 0,02334062 ! response to ionizing radiation GO:0010212 65 32 1,000 2,454E-03 0,02324873 ! regulation of axonogenesis GO:0050770 75 32 1,000 2,454E-03 0,02315755 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,454E-03 0,02306709 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,609E-03 0,02442365 ! glial cell differentiation GO:0010001 63 34 1,000 2,768E-03 0,02581139 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 2,931E-03 0,02722979 ! telencephalon development GO:0021537 68 35 1,000 2,931E-03 0,02712506 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,931E-03 0,02702113 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 3,099E-03 0,02845936 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,099E-03 0,02835115 ! meiosis I GO:0007127 65 37 1,000 3,271E-03 0,02981365 ! sister chromatid segregation GO:0000819 58 37 1,000 3,271E-03 0,02970114 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 3,271E-03 0,02958948 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,448E-03 0,03107047 ! regulation of neuron projection development GO:0010975 91 38 1,000 3,448E-03 0,03095454 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 3,448E-03 0,03083947 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 3,448E-03 0,03072525 ! learning GO:0007612 77 39 1,000 3,629E-03 0,03221899 ! segmentation GO:0035282 67 39 1,000 3,629E-03 0,03210053 ! cytokinesis GO:0000910 72 40 1,000 3,814E-03 0,03361663 ! gliogenesis GO:0042063 88 41 1,000 4,004E-03 0,03515967 ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,004E-03 0,03503182 ! T cell differentiation GO:0030217 81 41 1,000 4,004E-03 0,03490489 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,004E-03 0,03477888 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,198E-03 0,03633284 GO:0090047|positive regulation of transcription regulator activity, ! neuron migration GO:0001764 79 42 1,000 4,198E-03 0,03620262 ! regulation of protein secretion GO:0050708 71 42 1,000 4,198E-03 0,03607332 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 4,396E-03 0,03764281 ! double-strand break repair GO:0006302 81 44 1,000 4,599E-03 0,03923758 ! B cell differentiation GO:0030183 107 44 1,000 4,599E-03 0,03909894 ! glycolysis GO:0006096 65 45 1,000 4,806E-03 0,04071335 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 4,806E-03 0,0405705 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 4,806E-03 0,04042864 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 4,806E-03 0,04028778 ! positive regulation of protein transport GO:0051222 72 46 1,000 5,017E-03 0,04191097 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,232E-03 0,04355798 ! activation of caspase activity GO:0006919 84 48 1,000 5,451E-03 0,04522838 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 5,451E-03 0,04507296 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 5,451E-03 0,0449186 ! endocrine system development GO:0035270 104 49 1,000 5,675E-03 0,0466015 ! histone modification GO:0016570 91 50 1,000 5,903E-03 0,04830691 ! negative regulation of immune system process GO:0002683 95 50 1,000 5,903E-03 0,04814315 ! positive regulation of binding GO:0051099 78 51 1,000 6,135E-03 0,0498654 ! viral infectious cycle GO:0019058 99 51 1,000 6,135E-03 0,04969751 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 6,135E-03 0,04953074 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 1,000 6,371E-03 0,05126415 ! covalent chromatin modification GO:0016569 101 52 1,000 6,371E-03 0,05109327 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 6,371E-03 0,05092352 ! synapse organization GO:0050808 85 52 1,000 6,371E-03 0,0507549 ! response to UV GO:0009411 104 53 1,000 6,611E-03 0,05249387 ! cell recognition GO:0008037 85 54 1,000 6,855E-03 0,05425363 ! positive regulation of caspase activity GO:0043280 95 55 1,000 7,103E-03 0,05603381 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 1,000 7,103E-03 0,0558507 ! aging GO:0007568 103 55 1,000 7,103E-03 0,05566877 ! heart morphogenesis GO:0003007 97 55 1,000 7,103E-03 0,05548803 ! skeletal muscle fiber development GO:0048741 111 56 1,000 7,355E-03 0,05727258 ! nucleotide-excision repair GO:0006289 83 56 1,000 7,355E-03 0,05708783 ! muscle fiber development GO:0048747 112 57 1,000 7,612E-03 0,05888681 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 8,136E-03 0,06274273 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,01039094 0,07987416 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01039094 0,07961978 ! lung development GO:0030324 144 67 1,000 0,01039094 0,07936702 ! chromosome segregation GO:0007059 113 67 1,000 0,01039094 0,07911586 ! hexose catabolic process GO:0019320 104 67 1,000 0,01039094 0,07886628 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01039094 0,07861827 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,01069011 0,08062823 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01099307 0,08265411 ! respiratory tube development GO:0030323 150 70 1,000 0,01129979 0,08469562 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01140371 0,08520908 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01140371 0,08494527 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01140371 0,08468309 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01140371 0,08442253 ! neuron fate determination GO:0048664 7 5 0,000 0,01140371 0,08416357 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01140371 0,08390618 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01140371 0,08365037 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01140371 0,08339612 ! polyol transport GO:0015791 12 5 0,000 0,01140371 0,0831434 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01140371 0,08289221 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01140371 0,08264254 ! response to superoxide GO:0000303 10 5 0,000 0,01140371 0,08239436 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01140371 0,08214767 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01140371 0,08190246 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01140371 0,0816587 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01140371 0,08141639 ! female meiosis GO:0007143 7 5 0,000 0,01140371 0,08117551 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01140371 0,08093605 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01140371 0,08069801 ! cobalt ion transport GO:0006824 11 5 0,000 0,01140371 0,08046136 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01140371 0,08022609 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01140371 0,07999219 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01140371 0,07975966 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01140371 0,07952847 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01140371 0,07929862 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01140371 0,07907009 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01140371 0,07884288 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01140371 0,07861697 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01140371 0,07839235 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01140371 0,07816901 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01140371 0,07794694 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01140371 0,07772613 ! negative chemotaxis GO:0050919 14 5 0,000 0,01140371 0,07750656 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01140371 0,07728823 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01140371 0,07707113 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01140371 0,07685525 ! behavioral response to pain GO:0048266 9 5 0,000 0,01140371 0,07664057 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01140371 0,07642708 ! Notch receptor processing GO:0007220 8 5 0,000 0,01140371 0,07621478 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01140371 0,07600366 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01140371 0,07579371 ! micturition GO:0060073 9 5 0,000 0,01140371 0,07558491 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01140371 0,07537726 ! copulation GO:0007620 9 5 0,000 0,01140371 0,07517075 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01140371 0,07496536 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01140371 0,0747611 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01140371 0,07455794 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01140371 0,07435589 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01140371 0,07415493 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01140371 0,07395505 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01140371 0,07375624 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01140371 0,07355851 ! grooming behavior GO:0007625 6 5 0,000 0,01140371 0,07336182 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01140371 0,07316619 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01140371 0,0729716 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01140371 0,07277804 ! response to protozoan GO:0001562 10 5 0,000 0,01140371 0,07258551 ! lymph vessel development GO:0001945 10 5 0,000 0,01140371 0,07239399 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01140371 0,07220348 ! endochondral ossification GO:0001958 16 5 0,000 0,01140371 0,07201397 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01140371 0,07182545 ! parathyroid gland development GO:0060017 13 5 0,000 0,01140371 0,07163792 ! anagen GO:0042640 6 5 0,000 0,01140371 0,07145136 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01140371 0,07126577 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01140371 0,07108115 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01140371 0,07089747 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01140371 0,07071475 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01140371 0,07053296 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01140371 0,07035211 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01140371 0,07017218 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01140371 0,06999317 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01140371 0,06981507 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01140371 0,06963787 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01140371 0,06946158 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01140371 0,06928617 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01140371 0,06911164 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01140371 0,068938 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01140371 0,06876522 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01140371 0,06859331 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01140371 0,06842225 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01140371 0,06825205 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01140371 0,06808269 ! histidine catabolic process GO:0006548 6 5 0,000 0,01140371 0,06791416 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01140371 0,06774648 ! valine metabolic process GO:0006573 10 5 0,000 0,01140371 0,06757961 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01140371 0,06741357 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01140371 0,06724834 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01140371 0,06708392 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01140371 0,0669203 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01140371 0,06675748 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01140371 0,06659544 ! polyol catabolic process GO:0046174 7 5 0,000 0,01140371 0,06643419 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01140371 0,06627373 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01140371 0,06611403 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01140371 0,0659551 ! muscle cell migration GO:0014812 8 5 0,000 0,01140371 0,06579694 ! mitochondrial fission GO:0000266 8 5 0,000 0,01140371 0,06563953 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01140371 0,06548287 ! mRNA transcription GO:0009299 9 5 0,000 0,01140371 0,06532696 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01140371 0,06517179 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01140371 0,06501735 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01140371 0,06486365 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01140371 0,06471067 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01140371 0,06455841 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01140371 0,06440686 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01140371 0,06425602 ! response to food GO:0032094 6 5 0,000 0,01140371 0,06410589 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01140371 0,06395646 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01140371 0,06380773 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01140371 0,06365968 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01140371 0,06351232 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01140371 0,06336564 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01140371 0,06321964 ! forebrain neuron development GO:0021884 13 5 0,000 0,01140371 0,0630743 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01140371 0,06292964 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01140371 0,06278563 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01140371 0,06264229 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01140371 0,0624996 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01140371 0,06235755 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01140371 0,06221615 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01140371 0,06207539 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01140371 0,06193527 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01140371 0,06179577 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01140371 0,0616569 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01140371 0,06151866 ! basic amino acid transport GO:0015802 11 5 0,000 0,01140371 0,06138103 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01140371 0,06124402 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01140371 0,06110762 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01140371 0,06097183 ! depyrimidination GO:0045008 10 5 0,000 0,01140371 0,06083664 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01140371 0,06070204 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01140371 0,06056804 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01140371 0,06043463 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01140371 0,06030181 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01140371 0,06016957 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01140371 0,0600379 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01140371 0,05990682 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01140371 0,0597763 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01140371 0,05964635 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01140371 0,05951697 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01140371 0,05938814 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01140371 0,05925988 ! response to arsenic GO:0046685 10 5 0,000 0,01140371 0,05913216 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01140371 0,05900499 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01140371 0,05887837 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01140371 0,0587523 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01140371 0,05862676 ! response to cadmium ion GO:0046686 7 5 0,000 0,01140371 0,05850175 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01140371 0,05837728 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01140371 0,05825334 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01140371 0,05812992 ! decidualization GO:0046697 11 5 0,000 0,01140371 0,05800702 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01140371 0,05788465 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01140371 0,05776278 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01140371 0,05764143 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01140371 0,05752059 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01140371 0,05740026 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01140371 0,05728042 ! neural tube patterning GO:0021532 7 5 0,000 0,01140371 0,05716109 ! embryonic cleavage GO:0040016 6 5 0,000 0,01140371 0,05704225 ! peroxisome fission GO:0016559 5 5 0,000 0,01140371 0,05692391 ! histone demethylation GO:0016577 10 5 0,000 0,01140371 0,05680605 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01140371 0,05668868 ! mitotic recombination GO:0006312 9 5 0,000 0,01140371 0,0565718 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01140371 0,0564554 ! metaphase plate congression GO:0051310 7 5 0,000 0,01140371 0,05633947 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01140371 0,05622402 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01140371 0,05610904 ! enteric nervous system development GO:0048484 8 5 0,000 0,01140371 0,05599454 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01140371 0,05588049 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01140371 0,05576692 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01140371 0,0556538 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01140371 0,05554114 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01140371 0,05542893 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01140371 0,05531718 ! plasminogen activation GO:0031639 5 5 0,000 0,01140371 0,05520588 ! B cell homeostasis GO:0001782 13 5 0,000 0,01140371 0,05509503 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01140371 0,05498461 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01140371 0,05487464 ! metaphase GO:0051323 8 5 0,000 0,01140371 0,05476511 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01140371 0,05465602 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01140371 0,05454736 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01140371 0,05443913 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01140371 0,05433133 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01140371 0,05422396 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01140371 0,05411701 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01140371 0,05401048 ! response to redox state GO:0051775 5 5 0,000 0,01140371 0,05390437 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01140371 0,05379867 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01140371 0,05369339 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01140371 0,05358852 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01140371 0,05348406 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01140371 0,05338 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01140371 0,05327635 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01140371 0,05317311 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01140371 0,05307026 ! striatum development GO:0021756 9 5 0,000 0,01140371 0,0529678 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01140371 0,05286575 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01140371 0,05276408 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01140371 0,05266281 ! glial cell migration GO:0008347 11 5 0,000 0,01140371 0,05256192 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01140371 0,05246142 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01140371 0,0523613 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01140371 0,05226157 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01140371 0,05216221 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01140371 0,05206323 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01140371 0,05196463 ! neuroprotection GO:0043526 6 5 0,000 0,01140371 0,05186639 ! neural plate development GO:0001840 8 5 0,000 0,01140371 0,05176853 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01140371 0,05167104 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01140371 0,05157391 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01140371 0,05147715 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01140371 0,05138075 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01140371 0,05128471 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01140371 0,05118903 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01140371 0,05109371 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01140371 0,05099874 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01140371 0,05090412 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01140371 0,05080986 ! spindle assembly GO:0051225 6 5 0,000 0,01140371 0,05071594 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01140371 0,05062237 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01140371 0,05052914 ! drug metabolic process GO:0017144 6 5 0,000 0,01140371 0,05043625 ! stem cell division GO:0017145 11 5 0,000 0,01140371 0,05034371 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01140371 0,05025151 ! organ regeneration GO:0031100 7 5 0,000 0,01140371 0,05015964 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01140371 0,05006811 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01140371 0,04997691 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01140371 0,04988604 ! B cell activation GO:0042113 160 71 1,000 0,01161027 0,05069746 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01192447 0,05197516 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01192447 0,05188117 ! respiratory system development GO:0060541 153 72 1,000 0,01192447 0,05178752 ! learning or memory GO:0007611 147 73 1,000 0,0122424 0,05307245 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01256402 0,05436876 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,01256402 0,05427115 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01256402 0,05417389 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01288932 0,05547711 ! meiotic cell cycle GO:0051321 122 75 1,000 0,01288932 0,05537804 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01288932 0,05527933 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,01321828 0,05658929 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01321828 0,05648877 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01366902 0,05831147 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01366902 0,05820826 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01366902 0,05810542 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01366902 0,05800294 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01366902 0,05790083 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01366902 0,05779907 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01366902 0,05769766 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01366902 0,05759662 ! sleep GO:0030431 13 6 0,000 0,01366902 0,05749592 ! response to oxygen radical GO:0000305 11 6 0,000 0,01366902 0,05739558 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01366902 0,05729559 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01366902 0,05719595 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01366902 0,05709665 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01366902 0,05699769 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01366902 0,05689908 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01366902 0,05680081 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01366902 0,05670288 ! forebrain regionalization GO:0021871 8 6 0,000 0,01366902 0,05660528 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01366902 0,05650802 ! male meiosis GO:0007140 7 6 0,000 0,01366902 0,0564111 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01366902 0,0563145 ! response to zinc ion GO:0010043 9 6 0,000 0,01366902 0,05621824 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01366902 0,0561223 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01366902 0,05602669 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01366902 0,05593141 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01366902 0,05583645 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01366902 0,05574181 ! malate metabolic process GO:0006108 11 6 0,000 0,01366902 0,05564749 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01366902 0,05555349 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01366902 0,05545981 ! protein refolding GO:0042026 15 6 0,000 0,01366902 0,05536645 ! opsonization GO:0008228 8 6 0,000 0,01366902 0,05527339 ! mating behavior GO:0007617 7 6 0,000 0,01366902 0,05518065 ! neuron remodeling GO:0016322 15 6 0,000 0,01366902 0,05508822 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01366902 0,0549961 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01366902 0,05490429 ! equilibrioception GO:0050957 14 6 0,000 0,01366902 0,05481278 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01366902 0,05472158 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01366902 0,05463068 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01366902 0,05454008 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01366902 0,05444978 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01366902 0,05435978 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01366902 0,05427008 ! toxin metabolic process GO:0009404 11 6 0,000 0,01366902 0,05418067 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01366902 0,05409156 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01366902 0,05400274 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01366902 0,05391421 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01366902 0,05382597 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01366902 0,05373802 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01366902 0,05365036 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01366902 0,05356298 ! thymic T cell selection GO:0045061 12 6 0,000 0,01366902 0,05347588 ! protein lipoylation GO:0009249 10 6 0,000 0,01366902 0,05338907 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01366902 0,05330254 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01366902 0,05321629 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01366902 0,05313032 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01366902 0,05304463 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01366902 0,05295921 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01366902 0,05287407 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01366902 0,0527892 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01366902 0,0527046 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01366902 0,05262027 ! hyperosmotic response GO:0006972 9 6 0,000 0,01366902 0,05253621 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01366902 0,05245242 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01366902 0,0523689 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01366902 0,05228564 ! urea metabolic process GO:0019627 7 6 0,000 0,01366902 0,05220265 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01366902 0,05211992 ! neutrophil activation GO:0042119 8 6 0,000 0,01366902 0,05203745 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01366902 0,05195524 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01366902 0,05187329 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01366902 0,0517916 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01366902 0,05171017 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01366902 0,05162899 ! neuron apoptosis GO:0051402 9 6 0,000 0,01366902 0,05154807 ! nucleoside salvage GO:0043174 9 6 0,000 0,01366902 0,0514674 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01366902 0,05138698 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01366902 0,05130682 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01366902 0,0512269 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01366902 0,05114723 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01366902 0,05106781 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01366902 0,05098863 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01366902 0,0509097 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01366902 0,05083102 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01366902 0,05075258 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01366902 0,05067437 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01366902 0,05059641 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01366902 0,05051869 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01366902 0,05044121 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01366902 0,05036396 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01366902 0,05028696 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01366902 0,05021018 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01366902 0,05013364 ! neural nucleus development GO:0048857 14 6 0,000 0,01366902 0,05005733 ! response to UV-C GO:0010225 11 6 0,000 0,01366902 0,04998126 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01366902 0,04990542 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01366902 0,0498298 ! interaction with symbiont GO:0051702 13 6 0,000 0,01366902 0,04975442 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01366902 0,04967926 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01366902 0,04960433 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01366902 0,04952962 ! response to copper ion GO:0046688 10 6 0,000 0,01366902 0,04945514 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01366902 0,04938088 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01366902 0,04930685 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01366902 0,04923304 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01366902 0,04915944 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01366902 0,04908607 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01366902 0,04901292 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01366902 0,04893998 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01366902 0,04886726 ! hair follicle maturation GO:0048820 7 6 0,000 0,01366902 0,04879476 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01366902 0,04872247 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01366902 0,0486504 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01366902 0,04857854 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01366902 0,04850689 ! subpallium development GO:0021544 10 6 0,000 0,01366902 0,04843545 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01366902 0,04836422 ! histone ubiquitination GO:0016574 8 6 0,000 0,01366902 0,0482932 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01366902 0,04822239 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01366902 0,04815178 ! G2 phase GO:0051319 16 6 0,000 0,01366902 0,04808139 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01366902 0,0480112 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01366902 0,04794121 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01366902 0,04787142 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01366902 0,04780184 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01366902 0,04773247 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01366902 0,04766329 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01366902 0,04759431 ! receptor internalization GO:0031623 10 6 0,000 0,01366902 0,04752553 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01366902 0,04745695 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01366902 0,04738857 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01366902 0,04732039 ! protein deubiquitination GO:0016579 14 6 0,000 0,01366902 0,0472524 ! protein destabilization GO:0031648 9 6 0,000 0,01366902 0,0471846 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01366902 0,047117 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01366902 0,0470496 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01366902 0,04698238 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01366902 0,04691536 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01366902 0,04684853 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01366902 0,04678189 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01366902 0,04671544 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01366902 0,04664918 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01366902 0,0465831 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01366902 0,04651721 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01366902 0,04645151 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01366902 0,04638599 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01366902 0,04632066 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01366902 0,04625551 ! catecholamine transport GO:0051937 9 6 0,000 0,01366902 0,04619055 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01366902 0,04612576 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01366902 0,04606116 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01366902 0,04599674 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01366902 0,0459325 ! maternal placenta development GO:0001893 12 6 0,000 0,01366902 0,04586844 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01366902 0,04580455 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01366902 0,04574085 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01366902 0,04567732 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01366902 0,04561396 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01366902 0,04555079 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01366902 0,04548779 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01366902 0,04542496 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01422694 0,04721383 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01422694 0,0471488 ! protein import into nucleus GO:0006606 158 80 1,000 0,01457037 0,0482205 ! T cell activation GO:0042110 168 81 1,000 0,01491736 0,04930107 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01491736 0,04923344 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01491736 0,04916599 ! nuclear import GO:0051170 161 81 1,000 0,01491736 0,04909874 ! response to drug GO:0042493 143 82 1,000 0,01526791 0,05018387 ! response to oxygen levels GO:0070482 176 83 1,000 0,015622 0,05127766 ! tRNA transcription GO:0009304 14 7 0,000 0,01592922 0,05221486 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01592922 0,05214382 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01592922 0,05207297 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01592922 0,05200232 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01592922 0,05193185 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01592922 0,05186158 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01592922 0,05179149 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01592922 0,0517216 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01592922 0,0516519 ! prostate gland development GO:0030850 13 7 0,000 0,01592922 0,05158238 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01592922 0,05151305 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01592922 0,0514439 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01592922 0,05137494 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01592922 0,05130617 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01592922 0,05123758 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01592922 0,05116917 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01592922 0,05110094 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01592922 0,0510329 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01592922 0,05096503 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01592922 0,05089735 ! glycolipid transport GO:0046836 10 7 0,000 0,01592922 0,05082985 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01592922 0,05076252 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01592922 0,05069538 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01592922 0,05062841 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01592922 0,05056162 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01592922 0,050495 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01592922 0,05042856 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01592922 0,05036229 ! mRNA stabilization GO:0048255 18 7 0,000 0,01592922 0,0502962 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01592922 0,05023028 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01592922 0,05016454 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01592922 0,05009896 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01592922 0,05003356 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01592922 0,04996833 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01592922 0,04990326 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01592922 0,04983837 ! lipoprotein transport GO:0042953 14 7 0,000 0,01592922 0,04977364 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01592922 0,04970909 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01592922 0,0496447 ! rhythmic behavior GO:0007622 15 7 0,000 0,01592922 0,04958047 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01592922 0,04951642 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01592922 0,04945252 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01592922 0,0493888 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01592922 0,04932523 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01592922 0,04926183 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01592922 0,0491986 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01592922 0,04913552 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01592922 0,04907261 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01592922 0,04900985 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01592922 0,04894726 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01592922 0,04888483 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01592922 0,04882256 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01592922 0,04876044 ! spinal cord patterning GO:0021511 13 7 0,000 0,01592922 0,04869848 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01592922 0,04863668 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01592922 0,04857504 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01592922 0,04851355 ! adrenal gland development GO:0030325 17 7 0,000 0,01592922 0,04845222 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01592922 0,04839104 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01592922 0,04833002 ! ovulation GO:0030728 9 7 0,000 0,01592922 0,04826915 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01592922 0,04820844 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01592922 0,04814787 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01592922 0,04808746 ! microtubule nucleation GO:0007020 20 7 0,000 0,01592922 0,0480272 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01592922 0,04796709 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01592922 0,04790713 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01592922 0,04784732 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01592922 0,04778766 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01592922 0,04772815 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01592922 0,04766879 ! galactose metabolic process GO:0006012 13 7 0,000 0,01592922 0,04760957 ! vesicle fusion GO:0006906 17 7 0,000 0,01592922 0,0475505 ! response to dietary excess GO:0002021 8 7 0,000 0,01592922 0,04749158 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01592922 0,0474328 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01592922 0,04737417 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01592922 0,04731569 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01592922 0,04725734 ! purine salvage GO:0043101 10 7 0,000 0,01592922 0,04719915 ! nucleoside transport GO:0015858 8 7 0,000 0,01592922 0,04714109 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01592922 0,04708318 ! parturition GO:0007567 14 7 0,000 0,01592922 0,04702541 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01592922 0,04696778 ! rRNA modification GO:0000154 14 7 0,000 0,01592922 0,04691029 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01592922 0,04685294 ! spindle checkpoint GO:0031577 15 7 0,000 0,01592922 0,04679573 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01592922 0,04673867 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01592922 0,04668174 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01592922 0,04662495 ! centrosome duplication GO:0051298 13 7 0,000 0,01592922 0,04656829 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01592922 0,04651178 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01592922 0,0464554 ! fibrinolysis GO:0042730 10 7 0,000 0,01592922 0,04639916 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01592922 0,04634305 ! eating behavior GO:0042755 7 7 0,000 0,01592922 0,04628708 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01592922 0,04623125 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01592922 0,04617555 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01592922 0,04611998 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01592922 0,04606455 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01592922 0,04600925 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01592922 0,04595408 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01592922 0,04589905 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01592922 0,04584415 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01592922 0,04578937 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01592922 0,04573473 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01592922 0,04568022 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01592922 0,04562584 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01592922 0,04557159 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01592922 0,04551747 ! regulation of meiosis GO:0040020 12 7 0,000 0,01592922 0,04546347 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01592922 0,0454096 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01592922 0,04535587 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01592922 0,04530225 ! transcription termination GO:0006353 13 7 0,000 0,01592922 0,04524877 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01592922 0,04519541 ! anaphase GO:0051322 17 7 0,000 0,01592922 0,04514217 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01592922 0,04508907 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01592922 0,04503608 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01592922 0,04498322 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01592922 0,04493049 ! diuresis GO:0030146 12 7 0,000 0,01592922 0,04487788 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01592922 0,04482539 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01592922 0,04477302 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01592922 0,04472078 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01592922 0,04466866 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01592922 0,04461665 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01592922 0,04456477 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01592922 0,04451302 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01592922 0,04446138 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01592922 0,04440986 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01592922 0,04435846 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01592922 0,04430717 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01592922 0,04425601 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01592922 0,04420497 ! lymph node development GO:0048535 10 7 0,000 0,01592922 0,04415404 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01592922 0,04410323 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01592922 0,04405254 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01592922 0,04400196 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01592922 0,0439515 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01592922 0,04390115 ! adult feeding behavior GO:0008343 9 7 0,000 0,01592922 0,04385092 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01592922 0,04380081 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01592922 0,04375081 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01592922 0,04370092 ! muscle adaptation GO:0043500 14 7 0,000 0,01592922 0,04365115 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01592922 0,04360149 ! retina homeostasis GO:0001895 12 7 0,000 0,01592922 0,04355194 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01592922 0,0435025 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01592922 0,04345318 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01592922 0,04340397 ! protein prenylation GO:0018342 18 7 0,000 0,01592922 0,04335487 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01592922 0,04330588 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01592922 0,043257 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01592922 0,04320824 ! negative regulation of growth GO:0045926 155 84 1,000 0,0159796 0,04329608 ! tube morphogenesis GO:0035239 176 86 1,000 0,01670529 0,0452114 ! mitochondrion organization GO:0007005 148 86 1,000 0,01670529 0,0451606 ! alcohol catabolic process GO:0046164 130 86 1,000 0,01670529 0,04510992 ! protein localization in nucleus GO:0034504 176 87 1,000 0,01707335 0,0460521 ! regulation of DNA binding GO:0051101 155 88 1,000 0,01744485 0,04700147 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,01781979 0,04795795 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01781979 0,04790436 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01818432 0,04882976 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01818432 0,04877532 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01818432 0,04872101 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01818432 0,04866681 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01818432 0,04861274 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01818432 0,04855878 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01818432 0,04850495 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01818432 0,04845123 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01818432 0,04839764 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01818432 0,04834416 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01818432 0,0482908 ! meiotic prophase I GO:0007128 13 8 0,000 0,01818432 0,04823756 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01818432 0,04818443 ! oligopeptide transport GO:0006857 15 8 0,000 0,01818432 0,04813142 ! UTP metabolic process GO:0046051 8 8 0,000 0,01818432 0,04807853 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01818432 0,04802575 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01818432 0,0479731 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01818432 0,04792055 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01818432 0,04786812 ! succinate metabolic process GO:0006105 14 8 0,000 0,01818432 0,04781581 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01818432 0,04776361 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01818432 0,04771152 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01818432 0,04765955 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01818432 0,04760769 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01818432 0,04755594 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01818432 0,0475043 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01818432 0,04745278 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01818432 0,04740137 ! reflex GO:0060004 16 8 0,000 0,01818432 0,04735007 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01818432 0,04729888 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01818432 0,0472478 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01818432 0,04719683 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01818432 0,04714597 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01818432 0,04709522 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01818432 0,04704458 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01818432 0,04699405 ! pigment granule organization GO:0048753 16 8 0,000 0,01818432 0,04694363 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01818432 0,04689331 ! histidine metabolic process GO:0006547 16 8 0,000 0,01818432 0,04684311 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01818432 0,04679301 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01818432 0,04674302 ! glycine catabolic process GO:0006546 13 8 0,000 0,01818432 0,04669313 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01818432 0,04664335 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01818432 0,04659368 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01818432 0,04654411 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01818432 0,04649465 ! melanin metabolic process GO:0006582 15 8 0,000 0,01818432 0,04644529 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01818432 0,04639604 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01818432 0,04634689 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01818432 0,04629784 ! macrophage activation GO:0042116 12 8 0,000 0,01818432 0,0462489 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01818432 0,04620007 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01818432 0,04615133 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01818432 0,0461027 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01818432 0,04605417 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01818432 0,04600574 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01818432 0,04595742 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01818432 0,04590919 ! osteoblast development GO:0002076 16 8 0,000 0,01818432 0,04586107 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01818432 0,04581305 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01818432 0,04576513 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01818432 0,04571731 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01818432 0,04566959 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01818432 0,04562196 ! response to UV-B GO:0010224 16 8 0,000 0,01818432 0,04557444 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01818432 0,04552702 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01818432 0,04547969 ! intermediate filament organization GO:0045109 12 8 0,000 0,01818432 0,04543246 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01818432 0,04538533 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01818432 0,0453383 ! cellular extravasation GO:0045123 12 8 0,000 0,01818432 0,04529137 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01818432 0,04524453 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01818432 0,04519779 ! response to antibiotic GO:0046677 11 8 0,000 0,01818432 0,04515115 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01818432 0,0451046 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01818432 0,04505815 ! DNA topological change GO:0006265 12 8 0,000 0,01818432 0,04501179 ! response to tropane GO:0014073 15 8 0,000 0,01818432 0,04496553 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01818432 0,04491937 ! melanosome transport GO:0032402 13 8 0,000 0,01818432 0,0448733 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01818432 0,04482732 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01818432 0,04478144 ! mast cell activation GO:0045576 14 8 0,000 0,01818432 0,04473565 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01818432 0,04468995 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01818432 0,04464435 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01818432 0,04459884 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01818432 0,04455342 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01818432 0,0445081 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01818432 0,04446287 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01818432 0,04441773 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01818432 0,04437268 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01818432 0,04432772 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01818432 0,04428286 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01818432 0,04423808 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01818432 0,0441934 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01818432 0,0441488 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01818432 0,0441043 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01818432 0,04405988 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01818432 0,04401556 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01818432 0,04397132 ! hormone catabolic process GO:0042447 17 8 0,000 0,01818432 0,04392717 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01818432 0,04388311 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01818432 0,04383914 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01818432 0,04379526 ! ATP catabolic process GO:0006200 11 8 0,000 0,01818432 0,04375146 ! blastocyst growth GO:0001832 19 8 0,000 0,01818432 0,04370775 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01818432 0,04366413 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01818432 0,0436206 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01818432 0,04357715 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01818432 0,04353379 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01818432 0,04349052 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01818432 0,04344733 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01818432 0,04340423 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01818432 0,04336121 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01818432 0,04331828 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01818432 0,04327543 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01818432 0,04323267 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01818432 0,04318999 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01818432 0,0431474 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01818432 0,04310489 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01818432 0,04306246 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01818432 0,04302012 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,0193535 0,04574118 ! regulation of T cell activation GO:0050863 158 94 1,000 0,01974534 0,04662148 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,02014051 0,0475079 ! forebrain development GO:0030900 188 95 1,000 0,02014051 0,04746137 ! axon extension GO:0048675 15 9 0,000 0,02043432 0,04810662 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02043432 0,04805959 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02043432 0,04801266 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02043432 0,04796582 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02043432 0,04791907 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02043432 0,04787241 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02043432 0,04782584 ! phosphate transport GO:0006817 19 9 0,000 0,02043432 0,04777936 ! reproductive behavior GO:0019098 19 9 0,000 0,02043432 0,04773298 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02043432 0,04768668 ! CTP metabolic process GO:0046036 9 9 0,000 0,02043432 0,04764047 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02043432 0,04759435 ! GTP metabolic process GO:0046039 9 9 0,000 0,02043432 0,04754832 ! RNA methylation GO:0001510 15 9 0,000 0,02043432 0,04750238 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02043432 0,04745653 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02043432 0,04741077 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02043432 0,04736509 ! artery development GO:0060840 24 9 0,000 0,02043432 0,0473195 GO:0048844|artery morphogenesis, ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02043432 0,04727401 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02043432 0,04722859 ! chemosensory behavior GO:0007635 20 9 0,000 0,02043432 0,04718327 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02043432 0,04713803 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02043432 0,04709288 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02043432 0,04704781 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02043432 0,04700283 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02043432 0,04695794 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02043432 0,04691313 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02043432 0,04686841 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02043432 0,04682378 ! protein targeting to ER GO:0045047 22 9 0,000 0,02043432 0,04677922 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02043432 0,04673476 ! T cell selection GO:0045058 23 9 0,000 0,02043432 0,04669038 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02043432 0,04664608 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02043432 0,04660186 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02043432 0,04655773 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02043432 0,04651369 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02043432 0,04646972 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02043432 0,04642584 ! mannose metabolic process GO:0006013 13 9 0,000 0,02043432 0,04638204 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02043432 0,04633833 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02043432 0,04629469 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02043432 0,04625114 ! receptor clustering GO:0043113 18 9 0,000 0,02043432 0,04620767 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02043432 0,04616429 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02043432 0,04612098 ! ruffle organization GO:0031529 15 9 0,000 0,02043432 0,04607776 ! retinol metabolic process GO:0042572 18 9 0,000 0,02043432 0,04603461 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02043432 0,04599155 ! behavioral fear response GO:0001662 22 9 0,000 0,02043432 0,04594857 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02043432 0,04590566 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02043432 0,04586284 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02043432 0,0458201 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02043432 0,04577744 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02043432 0,04573485 ! segment specification GO:0007379 13 9 0,000 0,02043432 0,04569235 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02043432 0,04564992 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02043432 0,04560757 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02043432 0,04556531 ! response to amine stimulus GO:0014075 13 9 0,000 0,02043432 0,04552312 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02043432 0,045481 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02043432 0,04543897 ! erythrocyte development GO:0048821 15 9 0,000 0,02043432 0,04539701 ! gas homeostasis GO:0033483 16 9 0,000 0,02043432 0,04535513 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02043432 0,04531333 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02043432 0,04527161 ! renal water homeostasis GO:0003091 14 9 0,000 0,02043432 0,04522996 ! postreplication repair GO:0006301 22 9 0,000 0,02043432 0,04518839 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02043432 0,04514689 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02043432 0,04510547 ! icosanoid secretion GO:0032309 15 9 0,000 0,02043432 0,04506413 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02043432 0,04502286 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02043432 0,04498167 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,02043432 0,04494055 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02043432 0,04489951 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02043432 0,04485854 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02043432 0,04481765 ! sterol catabolic process GO:0016127 11 9 0,000 0,02043432 0,04477684 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02043432 0,04473609 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02043432 0,04469542 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02043432 0,04465483 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02043432 0,04461431 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02043432 0,04457386 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02043432 0,04453348 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02043432 0,04449318 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02043432 0,04445295 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02043432 0,0444128 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02043432 0,04437271 ! purine base metabolic process GO:0006144 21 9 0,000 0,02043432 0,0443327 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02043432 0,04429276 ! pigment granule transport GO:0051904 17 9 0,000 0,02043432 0,04425289 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02043432 0,0442131 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02043432 0,04417337 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02043432 0,04413372 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02043432 0,04409414 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02043432 0,04405463 ! mitochondrion localization GO:0051646 15 9 0,000 0,02043432 0,04401519 ! interphase GO:0051325 213 98 1,000 0,02134582 0,04593742 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02267924 0,0487634 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02267924 0,04871986 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02267924 0,0486764 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02267924 0,04863301 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02267924 0,04858971 ! synapsis GO:0007129 13 10 0,000 0,02267924 0,04854648 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02267924 0,04850333 ! N-glycan processing GO:0006491 20 10 0,000 0,02267924 0,04846025 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02267924 0,04841725 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02267924 0,04837433 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02267924 0,04833148 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02267924 0,04828871 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02267924 0,04824601 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02267924 0,04820339 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02267924 0,04816085 ! androgen metabolic process GO:0008209 17 10 0,000 0,02267924 0,04811838 ! phospholipid efflux GO:0033700 16 10 0,000 0,02267924 0,04807598 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02267924 0,04803366 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02267924 0,04799142 ! lung alveolus development GO:0048286 26 10 0,000 0,02267924 0,04794925 ! pathogenesis GO:0009405 13 10 0,000 0,02267924 0,04790715 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02267924 0,04786512 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02267924 0,04782317 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02267924 0,0477813 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02267924 0,04773949 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02267924 0,04769776 ! endoderm development GO:0007492 16 10 0,000 0,02267924 0,04765611 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02267924 0,04761452 ! arginine catabolic process GO:0006527 13 10 0,000 0,02267924 0,04757301 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02267924 0,04753157 ! proline metabolic process GO:0006560 13 10 0,000 0,02267924 0,0474902 ! L-serine metabolic process GO:0006563 18 10 0,000 0,02267924 0,04744891 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02267924 0,04740768 ! V(D)J recombination GO:0033151 28 10 0,000 0,02267924 0,04736653 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02267924 0,04732545 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02267924 0,04728444 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02267924 0,0472435 ! B cell proliferation GO:0042100 18 10 0,000 0,02267924 0,04720263 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02267924 0,04716183 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02267924 0,04712111 ! multicellular organism growth GO:0035264 18 10 0,000 0,02267924 0,04708045 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02267924 0,04703986 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02267924 0,04699935 ! epithelial cell development GO:0002064 20 10 0,000 0,02267924 0,0469589 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02267924 0,04691852 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02267924 0,04687821 ! macroautophagy GO:0016236 17 10 0,000 0,02267924 0,04683798 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02267924 0,04679781 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02267924 0,0467577 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02267924 0,04671767 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02267924 0,04667771 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02267924 0,04663781 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02267924 0,04659799 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02267924 0,04655823 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02267924 0,04651853 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02267924 0,04647891 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02267924 0,04643935 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02267924 0,04639987 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02267924 0,04636044 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02267924 0,04632109 ! response to dsRNA GO:0043331 20 10 0,000 0,02267924 0,0462818 ! DNA ligation GO:0006266 19 10 0,000 0,02267924 0,04624258 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02267924 0,04620342 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02267924 0,04616433 ! melanosome localization GO:0032400 16 10 0,000 0,02267924 0,04612531 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02267924 0,04608635 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02267924 0,04604746 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02267924 0,04600864 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02267924 0,04596987 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02267924 0,04593118 ! mRNA cleavage GO:0006379 17 10 0,000 0,02267924 0,04589255 ! protein sumoylation GO:0016925 15 10 0,000 0,02267924 0,04585398 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02267924 0,04581548 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02267924 0,04577705 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02267924 0,04573868 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02267924 0,04570037 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02267924 0,04566213 ! salivary gland development GO:0007431 27 10 0,000 0,02267924 0,04562395 ! prophase GO:0051324 15 10 0,000 0,02267924 0,04558583 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02267924 0,04554778 ! apical protein localization GO:0045176 15 10 0,000 0,02267924 0,04550979 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02267924 0,04547187 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02267924 0,04543401 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02267924 0,04539621 ! midbrain development GO:0030901 13 10 0,000 0,02267924 0,04535847 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02267924 0,0453208 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02267924 0,04528319 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02267924 0,04524564 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02267924 0,04520815 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02267924 0,04517073 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02267924 0,04513337 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02267924 0,04509607 ! detection of calcium ion GO:0005513 23 10 0,000 0,02267924 0,04505883 ! oocyte development GO:0048599 17 10 0,000 0,02267924 0,04502165 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02267924 0,04498454 ! blastocyst formation GO:0001825 17 10 0,000 0,02267924 0,04494748 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02267924 0,04491049 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02267924 0,04487355 ! activation of innate immune response GO:0002218 12 10 0,000 0,02267924 0,04483668 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02267924 0,04479987 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02267924 0,04476312 ! response to nicotine GO:0035094 20 10 0,000 0,02267924 0,04472643 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02267924 0,0446898 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02267924 0,04465323 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02267924 0,04461671 ! localization within membrane GO:0051668 20 10 0,000 0,02267924 0,04458026 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02491908 0,04894312 ! respiratory burst GO:0045730 17 11 0,000 0,02491908 0,0489032 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02491908 0,04886334 ! neuron fate specification GO:0048665 17 11 0,000 0,02491908 0,04882355 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02491908 0,04878382 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02491908 0,04874416 ! thyroid gland development GO:0030878 26 11 0,000 0,02491908 0,04870456 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02491908 0,04866503 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02491908 0,04862556 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02491908 0,04858616 ! response to pain GO:0048265 24 11 0,000 0,02491908 0,04854682 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02491908 0,04850754 ! T cell proliferation GO:0042098 26 11 0,000 0,02491908 0,04846832 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02491908 0,04842917 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02491908 0,04839009 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02491908 0,04835106 ! bone resorption GO:0045453 16 11 0,000 0,02491908 0,0483121 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02491908 0,0482732 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02491908 0,04823437 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02491908 0,04819559 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02491908 0,04815688 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02491908 0,04811823 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02491908 0,04807965 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02491908 0,04804112 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02491908 0,04800266 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02491908 0,04796425 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02491908 0,04792591 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02491908 0,04788763 ! UV protection GO:0009650 19 11 0,000 0,02491908 0,04784942 ! adult heart development GO:0007512 14 11 0,000 0,02491908 0,04781126 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02491908 0,04777316 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02491908 0,04773513 ! temperature homeostasis GO:0001659 17 11 0,000 0,02491908 0,04769715 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02491908 0,04765924 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02491908 0,04762138 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02491908 0,04758359 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02491908 0,04754585 ! regulation of organ growth GO:0046620 13 11 0,000 0,02491908 0,04750818 ! pigment granule localization GO:0051875 20 11 0,000 0,02491908 0,04747056 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02491908 0,047433 ! vasoconstriction GO:0042310 18 11 0,000 0,02491908 0,04739551 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02491908 0,04735807 ! embryonic axis specification GO:0000578 18 11 0,000 0,02491908 0,04732069 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02491908 0,04728337 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02491908 0,04724611 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02491908 0,04720891 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02491908 0,04717177 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02491908 0,04713468 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02491908 0,04709766 ! zymogen activation GO:0031638 15 11 0,000 0,02491908 0,04706069 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02491908 0,04702378 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02491908 0,04698693 ! nucleosome positioning GO:0016584 15 11 0,000 0,02491908 0,04695013 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02491908 0,04691339 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02491908 0,04687671 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02491908 0,04684009 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02491908 0,04680353 ! acid secretion GO:0046717 18 11 0,000 0,02491908 0,04676702 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02491908 0,04673057 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02491908 0,04669417 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02491908 0,04665783 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02491908 0,04662155 ! oocyte differentiation GO:0009994 18 11 0,000 0,02491908 0,04658533 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02491908 0,04654916 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02491908 0,04651305 ! cholesterol efflux GO:0033344 19 11 0,000 0,02491908 0,04647699 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02491908 0,04644099 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02491908 0,04640504 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02491908 0,04636916 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02491908 0,04633332 ! embryonic gut development GO:0048566 15 11 0,000 0,02491908 0,04629754 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02491908 0,04626182 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02491908 0,04622615 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02491908 0,04619054 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02491908 0,04615498 ! defense response to fungus GO:0050832 13 11 0,000 0,02491908 0,04611948 ! developmental induction GO:0031128 19 11 0,000 0,02491908 0,04608403 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02491908 0,04604863 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02491908 0,04601329 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02491908 0,045978 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02491908 0,04594277 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02491908 0,04590759 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02491908 0,04587247 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02715387 0,04994818 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02715387 0,04991002 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02715387 0,04987193 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02715387 0,04983388 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02715387 0,0497959 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02715387 0,04975798 ! cartilage condensation GO:0001502 20 12 0,000 0,02715387 0,04972011 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02715387 0,0496823 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02715387 0,04964455 ! protein complex disassembly GO:0043241 27 12 0,000 0,02715387 0,04960685 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02715387 0,04956921 ! hippocampus development GO:0021766 26 12 0,000 0,02715387 0,04953163 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02715387 0,04949411 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02715387 0,04945664 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02715387 0,04941923 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02715387 0,04938188 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02715387 0,04934458 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02715387 0,04930734 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02715387 0,04927015 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02715387 0,04923302 ! drug transport GO:0015893 16 12 0,000 0,02715387 0,04919595 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02715387 0,04915893 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02715387 0,04912197 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02715387 0,04908507 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02715387 0,04904821 ! focal adhesion formation GO:0048041 35 12 0,000 0,02715387 0,04901142 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02715387 0,04897468 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02715387 0,04893799 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02715387 0,04890136 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02715387 0,04886479 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02715387 0,04882827 ! fear response GO:0042596 26 12 0,000 0,02715387 0,0487918 ! monoamine transport GO:0015844 18 12 0,000 0,02715387 0,04875539 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02715387 0,04871903 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02715387 0,04868273 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02715387 0,04864648 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02715387 0,04861028 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02715387 0,04857414 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02715387 0,04853806 ! protein homotetramerization GO:0051289 21 12 0,000 0,02715387 0,04850202 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02715387 0,04846604 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02715387 0,04843011 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02715387 0,04839424 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02715387 0,04835842 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02715387 0,04832265 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02715387 0,04828693 ! cranial nerve development GO:0021545 20 12 0,000 0,02715387 0,04825127 ! fucose catabolic process GO:0019317 22 12 0,000 0,02715387 0,04821566 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02715387 0,0481801 ! histone methylation GO:0016571 26 12 0,000 0,02715387 0,0481446 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02715387 0,04810915 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02715387 0,04807375 ! gland morphogenesis GO:0022612 29 12 0,000 0,02715387 0,0480384 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02715387 0,0480031 ! T cell homeostasis GO:0043029 25 12 0,000 0,02715387 0,04796786 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02715387 0,04793266 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02715387 0,04789752 ! spleen development GO:0048536 22 12 0,000 0,02715387 0,04786243 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02715387 0,0478274 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02715387 0,04779241 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02715387 0,04775747 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02715387 0,04772259 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02715387 0,04768775 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02715387 0,04765297 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02715387 0,04761824 ! response to cold GO:0009409 17 12 0,000 0,02715387 0,04758356 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02715387 0,04754892 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02715387 0,04751434 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02938362 0,05137862 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02938362 0,05134131 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02938362 0,05130405 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02938362 0,05126685 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02938362 0,0512297 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02938362 0,0511926 ! lipid localization GO:0010876 28 13 0,000 0,02938362 0,05115556 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02938362 0,05111857 ! organelle fusion GO:0048284 32 13 0,000 0,02938362 0,05108163 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02938362 0,05104475 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02938362 0,05100792 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02938362 0,05097115 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02938362 0,05093442 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02938362 0,05089775 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02938362 0,05086114 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02938362 0,05082457 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02938362 0,05078806 ! methionine metabolic process GO:0006555 27 13 0,000 0,02938362 0,0507516 ! plasma membrane organization GO:0007009 24 13 0,000 0,02938362 0,05071519 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02938362 0,05067884 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02938362 0,05064254 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02938362 0,05060629 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02938362 0,05057009 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02938362 0,05053394 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02938362 0,05049784 ! exocrine system development GO:0035272 32 13 0,000 0,02938362 0,0504618 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02938362 0,05042581 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02938362 0,05038987 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02938362 0,05035398 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02938362 0,05031814 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02938362 0,05028235 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02938362 0,05024661 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02938362 0,05021092 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02938362 0,05017529 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02938362 0,0501397 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02938362 0,05010417 ! ribosome assembly GO:0042255 17 13 0,000 0,02938362 0,05006868 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02938362 0,05003325 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02938362 0,04999787 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02938362 0,04996253 ! chromatin silencing GO:0006342 26 13 0,000 0,02938362 0,04992725 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02938362 0,04989201 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02938362 0,04985683 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02938362 0,04982169 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02938362 0,04978661 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02938362 0,04975157 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02938362 0,04971658 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02938362 0,04968165 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02938362 0,04964676 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02938362 0,04961192 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02938362 0,04957713 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02938362 0,04954238 ! embryonic placenta development GO:0001892 23 13 0,000 0,02938362 0,04950769 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02938362 0,04947305 ! insulin secretion GO:0030073 23 13 0,000 0,02938362 0,04943845 ! actin filament polymerization GO:0030041 24 13 0,000 0,02938362 0,0494039 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02938362 0,0493694 ! acrosome reaction GO:0007340 18 13 0,000 0,02938362 0,04933495 ! rRNA transcription GO:0009303 25 14 0,000 0,03160832 0,05303321 ! lactation GO:0007595 26 14 0,000 0,03160832 0,05299625 ! reproductive cellular process GO:0048610 20 14 0,000 0,03160832 0,05295935 ! tRNA modification GO:0006400 20 14 0,000 0,03160832 0,05292249 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03160832 0,05288569 ! regulation of S phase GO:0033261 23 14 0,000 0,03160832 0,05284894 ! water transport GO:0006833 21 14 0,000 0,03160832 0,05281224 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03160832 0,05277559 ! non-recombinational repair GO:0000726 25 14 0,000 0,03160832 0,05273899 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03160832 0,05270244 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03160832 0,05266594 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03160832 0,0526295 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03160832 0,0525931 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03160832 0,05255675 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03160832 0,05252046 ! palate development GO:0060021 31 14 0,000 0,03160832 0,05248421 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03160832 0,05244802 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03160832 0,05241187 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03160832 0,05237577 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03160832 0,05233973 ! arginine metabolic process GO:0006525 17 14 0,000 0,03160832 0,05230373 ! regulation of heart rate GO:0002027 24 14 0,000 0,03160832 0,05226778 ! organic alcohol transport GO:0015850 29 14 0,000 0,03160832 0,05223188 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03160832 0,05219603 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03160832 0,05216023 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03160832 0,05212448 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03160832 0,05208878 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03160832 0,05205313 ! L-amino acid transport GO:0015807 30 14 0,000 0,03160832 0,05201753 ! bone mineralization GO:0030282 17 14 0,000 0,03160832 0,05198197 ! stem cell development GO:0048864 43 14 0,000 0,03160832 0,05194646 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03160832 0,05191101 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03160832 0,0518756 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03160832 0,05184023 ! cerebellum development GO:0021549 21 14 0,000 0,03160832 0,05180492 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03160832 0,05176965 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03160832 0,05173444 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03160832 0,05169927 ! cofactor transport GO:0051181 26 14 0,000 0,03160832 0,05166415 ! NADP metabolic process GO:0006739 24 14 0,000 0,03160832 0,05162907 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03160832 0,05159405 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03160832 0,05155907 ! intestinal absorption GO:0050892 25 14 0,000 0,03160832 0,05152413 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03160832 0,05148925 ! oxygen transport GO:0015671 21 14 0,000 0,03160832 0,05145441 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03160832 0,05141962 ! male genitalia development GO:0030539 24 14 0,000 0,03160832 0,05138488 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03160832 0,05135018 ! regulation of axon extension GO:0030516 37 14 0,000 0,03160832 0,05131553 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03160832 0,05128093 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,033828 0,05484513 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,033828 0,0548082 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,033828 0,05477131 ! superoxide anion generation GO:0042554 20 15 0,000 0,033828 0,05473448 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,033828 0,0546977 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,033828 0,05466096 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,033828 0,05462428 ! copper ion transport GO:0006825 20 15 0,000 0,033828 0,05458764 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,033828 0,05455105 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,033828 0,05451452 ! sulfate transport GO:0008272 23 15 0,000 0,033828 0,05447803 ! response to cAMP GO:0051591 22 15 0,000 0,033828 0,05444159 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,033828 0,0544052 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,033828 0,05436885 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,033828 0,05433256 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,033828 0,05429631 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,033828 0,05426012 ! response to hexose stimulus GO:0009746 22 15 0,000 0,033828 0,05422397 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,033828 0,05418786 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,033828 0,05415181 ! vesicle coating GO:0006901 33 15 0,000 0,033828 0,05411581 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,033828 0,05407985 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,033828 0,05404394 ! regulation of exocytosis GO:0017157 22 15 0,000 0,033828 0,05400808 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,033828 0,05397226 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,033828 0,0539365 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,033828 0,05390078 ! regulation of vasodilation GO:0042312 26 15 0,000 0,033828 0,0538651 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,033828 0,05382948 ! histone deacetylation GO:0016575 20 15 0,000 0,033828 0,0537939 ! mRNA splice site selection GO:0006376 38 15 0,000 0,033828 0,05375837 ! tissue regeneration GO:0042246 26 15 0,000 0,033828 0,05372289 ! water homeostasis GO:0030104 27 15 0,000 0,033828 0,05368745 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,033828 0,05365206 ! muscle maintenance GO:0046716 26 15 0,000 0,033828 0,05361671 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,033828 0,05358142 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,033828 0,05354617 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,033828 0,05351096 ! dopamine metabolic process GO:0042417 35 15 0,000 0,033828 0,0534758 ! heme biosynthetic process GO:0006783 29 15 0,000 0,033828 0,05344069 ! cell killing GO:0001906 29 15 0,000 0,033828 0,05340563 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,033828 0,0533706 ! detection of bacterium GO:0016045 18 15 0,000 0,033828 0,05333563 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,033828 0,0533007 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,033828 0,05326582 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,033828 0,05323098 ! peptide hormone processing GO:0016486 23 15 0,000 0,033828 0,05319619 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03604267 0,05664184 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03604267 0,05660487 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03604267 0,05656794 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03604267 0,05653107 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03604267 0,05649424 ! bone remodeling GO:0046849 27 16 0,000 0,03604267 0,05645746 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03604267 0,05642073 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03604267 0,05638404 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03604267 0,05634741 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03604267 0,05631082 ! startle response GO:0001964 28 16 0,000 0,03604267 0,05627428 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03604267 0,05623778 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03604267 0,05620133 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03604267 0,05616493 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03604267 0,05612858 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03604267 0,05609228 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03604267 0,05605602 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03604267 0,05601981 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03604267 0,05598364 ! response to osmotic stress GO:0006970 25 16 0,000 0,03604267 0,05594752 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03604267 0,05591145 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03604267 0,05587542 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03604267 0,05583945 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03604267 0,05580351 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03604267 0,05576763 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03604267 0,05573179 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03604267 0,05569599 ! axon cargo transport GO:0008088 43 16 0,000 0,03604267 0,05566024 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03604267 0,05562454 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03604267 0,05558888 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03604267 0,05555327 ! DNA replication initiation GO:0006270 27 16 0,000 0,03604267 0,05551771 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03604267 0,05548219 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03604267 0,05544671 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03604267 0,05541128 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03604267 0,0553759 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03604267 0,05534056 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03604267 0,05530527 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03604267 0,05527002 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03604267 0,05523481 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03604267 0,05519966 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03604267 0,05516454 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03604267 0,05512947 ! defense response to virus GO:0051607 37 16 0,000 0,03604267 0,05509445 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03825233 0,05843499 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03825233 0,05839791 ! metencephalon development GO:0022037 30 17 0,000 0,03825233 0,05836088 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03825233 0,0583239 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03825233 0,05828696 ! signal complex assembly GO:0007172 41 17 0,000 0,03825233 0,05825007 ! endothelial cell migration GO:0043542 28 17 0,000 0,03825233 0,05821322 ! inositol metabolic process GO:0006020 28 17 0,000 0,03825233 0,05817643 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03825233 0,05813968 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03825233 0,05810297 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03825233 0,05806631 ! adult walking behavior GO:0007628 33 17 0,000 0,03825233 0,0580297 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03825233 0,05799314 ! heart looping GO:0001947 30 17 0,000 0,03825233 0,05795662 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03825233 0,05792014 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03825233 0,05788371 ! myoblast differentiation GO:0045445 45 17 0,000 0,03825233 0,05784733 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03825233 0,057811 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03825233 0,05777471 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03825233 0,05773846 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03825233 0,05770226 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03825233 0,05766611 ! glycine metabolic process GO:0006544 28 17 0,000 0,03825233 0,05763 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03825233 0,05759393 ! NAD metabolic process GO:0019674 29 17 0,000 0,03825233 0,05755792 ! membrane budding GO:0006900 37 17 0,000 0,03825233 0,05752194 ! DNA integration GO:0015074 29 17 0,000 0,03825233 0,05748601 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03825233 0,05745013 ! regulation of protein binding GO:0043393 33 17 0,000 0,03825233 0,05741429 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03825233 0,0573785 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03825233 0,05734275 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03825233 0,05730704 ! genitalia development GO:0048806 30 17 0,000 0,03825233 0,05727138 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03825233 0,05723576 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03825233 0,05720019 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03825233 0,05716466 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03825233 0,05712918 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03825233 0,05709374 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03825233 0,05705834 ! steroid catabolic process GO:0006706 31 17 0,000 0,03825233 0,05702299 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03825233 0,05698768 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03825233 0,05695242 ! gas transport GO:0015669 25 17 0,000 0,03825233 0,0569172 ! organic cation transport GO:0015695 31 17 0,000 0,03825233 0,05688202 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03825233 0,05684688 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03825233 0,05681179 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03825233 0,05677675 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03825233 0,05674174 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03825233 0,05670678 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,040457 0,05993814 ! neuron maturation GO:0042551 42 18 0,000 0,040457 0,05990126 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,040457 0,05986442 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,040457 0,05982762 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,040457 0,05979088 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,040457 0,05975417 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,040457 0,05971751 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,040457 0,0596809 ! memory GO:0007613 31 18 0,000 0,040457 0,05964433 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,040457 0,0596078 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,040457 0,05957132 ! patterning of blood vessels GO:0001569 39 18 0,000 0,040457 0,05953489 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,040457 0,0594985 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,040457 0,05946215 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,040457 0,05942585 ! glutamine metabolic process GO:0006541 29 18 0,000 0,040457 0,05938959 ! response to retinoic acid GO:0032526 26 18 0,000 0,040457 0,05935338 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,040457 0,05931721 ! response to fungus GO:0009620 21 18 0,000 0,040457 0,05928109 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,040457 0,05924501 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,040457 0,05920897 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,040457 0,05917298 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,040457 0,05913703 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,040457 0,05910112 ! vitamin transport GO:0051180 27 18 0,000 0,040457 0,05906526 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,040457 0,05902944 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,040457 0,05899366 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,040457 0,05895793 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,040457 0,05892224 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,040457 0,0588866 ! nerve development GO:0021675 28 18 0,000 0,040457 0,05885099 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,040457 0,05881543 ! protein secretion GO:0009306 39 19 0,000 0,04265669 0,06197584 ! positive regulation of translation GO:0045727 30 19 0,000 0,04265669 0,06193844 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04265669 0,06190108 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04265669 0,06186377 ! skin development GO:0043588 36 19 0,000 0,04265669 0,06182651 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04265669 0,06178928 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04265669 0,0617521 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04265669 0,06171497 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04265669 0,06167788 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04265669 0,06164084 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04265669 0,06160384 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04265669 0,06156689 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04265669 0,06152998 ! pigmentation during development GO:0048066 41 19 0,000 0,04265669 0,06149311 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04265669 0,06145629 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04265669 0,06141951 ! heme metabolic process GO:0042168 36 19 0,000 0,04265669 0,06138277 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04265669 0,06134608 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04265669 0,06130944 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04265669 0,06127283 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04265669 0,06123628 ! peptide cross-linking GO:0018149 37 19 0,000 0,04265669 0,06119976 ! protein export from nucleus GO:0006611 36 19 0,000 0,04265669 0,06116329 ! heart process GO:0003015 30 19 0,000 0,04265669 0,06112686 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04265669 0,06109048 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04265669 0,06105413 ! visual learning GO:0008542 36 19 0,000 0,04265669 0,06101783 ! cellular pigmentation GO:0033059 36 19 0,000 0,04265669 0,06098158 ! G1 phase GO:0051318 40 19 0,000 0,04265669 0,06094537 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04265669 0,0609092 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04265669 0,06087307 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04265669 0,06083699 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04265669 0,06080095 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04265669 0,06076495 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04265669 0,06072899 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04265669 0,06069308 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04265669 0,06065721 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04265669 0,06062138 ! cilium assembly GO:0042384 37 19 0,000 0,04265669 0,0605856 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04265669 0,06054985 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04485141 0,06362765 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04485141 0,06359016 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04485141 0,06355271 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04485141 0,0635153 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04485141 0,06347794 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04485141 0,06344062 ! response to vitamin GO:0033273 31 20 0,000 0,04485141 0,06340335 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04485141 0,06336612 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04485141 0,06332893 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04485141 0,06329179 ! response to alkaloid GO:0043279 38 20 0,000 0,04485141 0,06325469 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04485141 0,06321763 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04485141 0,06318062 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04485141 0,06314365 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04485141 0,06310672 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04485141 0,06306984 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04485141 0,063033 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04485141 0,0629962 ! body fluid secretion GO:0007589 31 20 0,000 0,04485141 0,06295945 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04485141 0,06292274 ! peptide secretion GO:0002790 35 20 0,000 0,04485141 0,06288607 ! stem cell differentiation GO:0048863 53 20 0,000 0,04485141 0,06284944 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04485141 0,06281286 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04485141 0,06277632 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04485141 0,06273982 ! sensory perception of pain GO:0019233 30 20 0,000 0,04485141 0,06270337 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04485141 0,06266695 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04485141 0,06263058 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04485141 0,06259425 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04485141 0,06255797 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04485141 0,06252172 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04485141 0,06248552 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04485141 0,06244936 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04485141 0,06241324 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04485141 0,06237716 ! regulation of glucose import GO:0046324 29 20 0,000 0,04485141 0,06234113 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04485141 0,06230514 ! actin filament-based movement GO:0030048 43 20 0,000 0,04485141 0,06226918 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04485141 0,06223327 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04485141 0,0621974 ! negative regulation of translation GO:0017148 29 20 0,000 0,04485141 0,06216158 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04485141 0,06212579 ! regulation of cell killing GO:0031341 42 21 0,000 0,04704117 0,06512144 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04704117 0,06508399 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04704117 0,06504659 ! hormone secretion GO:0046879 38 21 0,000 0,04704117 0,06500923 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04704117 0,06497191 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04704117 0,06493463 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04704117 0,0648974 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04704117 0,06486021 ! axis specification GO:0009798 38 21 0,000 0,04704117 0,06482306 ! ovarian follicle development GO:0001541 35 21 0,000 0,04704117 0,06478595 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04704117 0,06474889 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04704117 0,06471187 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04704117 0,06467489 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04704117 0,06463796 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04704117 0,06460106 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04704117 0,06456421 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04704117 0,0645274 ! cytolysis GO:0019835 24 21 0,000 0,04704117 0,06449063 ! vasodilation GO:0042311 39 21 0,000 0,04704117 0,06445391 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04704117 0,06441722 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04704117 0,06438058 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04704117 0,06434398 ! oogenesis GO:0048477 36 21 0,000 0,04704117 0,06430742 ! DNA modification GO:0006304 34 21 0,000 0,04704117 0,0642709 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04704117 0,06423443 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04704117 0,06419799 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04704117 0,0641616 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04704117 0,06412525 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04704117 0,06408894 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04704117 0,06405267 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04704117 0,06401644 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04704117 0,06398025 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04704117 0,0639441 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04704117 0,063908 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04704117 0,06387193 ! collagen catabolic process GO:0030574 28 21 0,000 0,04704117 0,06383591 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04704117 0,06379992 ! gut development GO:0048565 39 21 0,000 0,04704117 0,06376398 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04922599 0,06668791 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04922599 0,06665038 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04922599 0,06661289 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04922599 0,06657545 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04922599 0,06653805 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04922599 0,06650069 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04922599 0,06646337 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04922599 0,06642609 ! regeneration GO:0031099 41 22 0,000 0,04922599 0,06638886 ! keratinization GO:0031424 28 22 0,000 0,04922599 0,06635167 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04922599 0,06631451 ! sensory perception of taste GO:0050909 28 22 0,000 0,04922599 0,06627741 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04922599 0,06624034 ! vacuolar transport GO:0007034 36 22 0,000 0,04922599 0,06620331 ! lysosome organization GO:0007040 41 22 0,000 0,04922599 0,06616633 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04922599 0,06612938 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04922599 0,06609248 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04922599 0,06605562 ! fucose metabolic process GO:0006004 39 22 0,000 0,04922599 0,0660188 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04922599 0,06598202 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04922599 0,06594528 ! ureteric bud development GO:0001657 43 22 0,000 0,04922599 0,06590858 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04922599 0,06587193 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04922599 0,06583531 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04922599 0,06579874 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04922599 0,0657622 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04922599 0,06572571 ! sarcomere organization GO:0045214 30 22 0,000 0,04922599 0,06568925 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04922599 0,06565284 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04922599 0,06561647 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04922599 0,06558013 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04922599 0,06554384 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04922599 0,06550759 ! protein stabilization GO:0050821 39 22 0,000 0,04922599 0,06547138 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05140586 0,06833288 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05140586 0,06829515 ! gluconeogenesis GO:0006094 33 23 0,000 0,05140586 0,06825746 ! viral genome replication GO:0019079 41 23 0,000 0,05140586 0,06821981 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05140586 0,0681822 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05140586 0,06814463 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05140586 0,06810711 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05140586 0,06806962 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05140586 0,06803218 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05140586 0,06799478 ! visual behavior GO:0007632 42 23 0,000 0,05140586 0,06795742 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05140586 0,0679201 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05140586 0,06788283 ! response to ethanol GO:0045471 46 23 0,000 0,05140586 0,06784559 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05140586 0,06780839 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05140586 0,06777124 ! peroxisome organization GO:0007031 37 23 0,000 0,05140586 0,06773412 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05140586 0,06769705 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05140586 0,06766002 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05140586 0,06762302 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05140586 0,06758607 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05140586 0,06754916 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05140586 0,06751229 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05140586 0,06747545 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05140586 0,06743866 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05140586 0,06740191 ! fatty acid transport GO:0015908 44 23 0,000 0,05140586 0,0673652 ! platelet activation GO:0030168 37 23 0,000 0,05140586 0,06732853 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05140586 0,0672919 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05140586 0,06725531 ! hormone transport GO:0009914 40 23 0,000 0,05140586 0,06721875 ! cell-cell recognition GO:0009988 25 23 0,000 0,05140586 0,06718224 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05140586 0,06714577 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05140586 0,06710934 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05140586 0,06707294 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05140586 0,06703659 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05140586 0,06700028 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05358082 0,06979721 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05358082 0,06975944 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05358082 0,06972171 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05358082 0,06968402 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05358082 0,06964638 ! vesicle docking GO:0048278 47 24 0,000 0,05358082 0,06960877 ! spinal cord development GO:0021510 47 24 0,000 0,05358082 0,0695712 ! vacuole organization GO:0007033 43 24 0,000 0,05358082 0,06953368 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05358082 0,0694962 ! digestive system process GO:0022600 39 24 0,000 0,05358082 0,06945875 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05358082 0,06942135 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05358082 0,06938398 ! regulation of behavior GO:0050795 43 24 0,000 0,05358082 0,06934666 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05358082 0,06930938 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05358082 0,06927213 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05358082 0,06923493 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05358082 0,06919777 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05358082 0,06916064 ! membrane depolarization GO:0051899 39 24 0,000 0,05358082 0,06912356 ! pentose metabolic process GO:0019321 35 24 0,000 0,05358082 0,06908652 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05358082 0,06904951 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05358082 0,06901255 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05358082 0,06897562 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05358082 0,06893874 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05358082 0,06890189 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05358082 0,06886509 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05358082 0,06882832 ! regulation of amine transport GO:0051952 40 24 0,000 0,05358082 0,06879159 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05575085 0,07153949 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05575085 0,07150136 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05575085 0,07146327 ! phototransduction GO:0007602 33 25 0,000 0,05575085 0,07142521 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05575085 0,0713872 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05575085 0,07134923 ! sperm motility GO:0030317 31 25 0,000 0,05575085 0,0713113 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05575085 0,07127341 ! receptor metabolic process GO:0043112 46 25 0,000 0,05575085 0,07123556 ! chromosome condensation GO:0030261 45 25 0,000 0,05575085 0,07119774 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05575085 0,07115997 ! neural crest cell development GO:0014032 54 25 0,000 0,05575085 0,07112224 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05575085 0,07108455 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05575085 0,0710469 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05575085 0,07100929 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05575085 0,07097172 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05575085 0,07093419 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05575085 0,0708967 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05575085 0,07085925 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05575085 0,07082183 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05575085 0,07078446 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05575085 0,07074713 ! telomere organization GO:0032200 43 25 0,000 0,05575085 0,07070983 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05575085 0,07067258 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05575085 0,07063536 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05791599 0,07333993 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05791599 0,07330135 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05791599 0,07326281 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05791599 0,07322431 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05791599 0,07318585 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05791599 0,07314743 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05791599 0,07310906 ! molting cycle process GO:0022404 50 26 0,000 0,05791599 0,07307072 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05791599 0,07303242 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05791599 0,07299417 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05791599 0,07295595 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05791599 0,07291777 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05791599 0,07287963 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05791599 0,07284154 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05791599 0,07280348 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05791599 0,07276546 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05791599 0,07272749 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05791599 0,07268955 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05791599 0,07265165 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05791599 0,07261379 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05791599 0,07257597 ! blastocyst development GO:0001824 49 26 0,000 0,05791599 0,07253819 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05791599 0,07250045 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05791599 0,07246275 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05791599 0,07242508 ! neuron fate commitment GO:0048663 48 27 0,000 0,06007623 0,07508748 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06007623 0,07504849 ! iron ion transport GO:0006826 59 27 0,000 0,06007623 0,07500955 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06007623 0,07497064 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06007623 0,07493178 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06007623 0,07489295 ! fat cell differentiation GO:0045444 50 27 0,000 0,06007623 0,07485417 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06007623 0,07481542 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06007623 0,07477672 ! autophagy GO:0006914 41 27 0,000 0,06007623 0,07473806 ! male gonad development GO:0008584 44 27 0,000 0,06007623 0,07469943 ! response to toxin GO:0009636 47 27 0,000 0,06007623 0,07466085 ! primary neural tube formation GO:0014020 51 27 0,000 0,06007623 0,0746223 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06007623 0,0745838 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06007623 0,07454533 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06007623 0,07450691 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06007623 0,07446852 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06007623 0,07443018 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06007623 0,07439187 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06223158 0,07702119 ! circadian rhythm GO:0007623 50 28 0,000 0,06223158 0,07698159 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06223158 0,07694203 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06223158 0,07690251 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06223158 0,07686304 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06223158 0,0768236 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06223158 0,0767842 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06223158 0,07674485 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06223158 0,07670553 ! synaptogenesis GO:0007416 42 28 0,000 0,06223158 0,07666625 ! lipid oxidation GO:0034440 43 28 0,000 0,06223158 0,07662702 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06223158 0,07658782 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06223158 0,07654867 ! translational initiation GO:0006413 65 29 0,000 0,06438207 0,07915343 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06438207 0,07911301 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06438207 0,07907262 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06438207 0,07903228 ! catechol metabolic process GO:0009712 54 29 0,000 0,06438207 0,07899198 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06438207 0,07895172 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06438207 0,0789115 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06438207 0,07887132 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06438207 0,07883118 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06438207 0,07879108 ! cell fate determination GO:0001709 60 29 0,000 0,06438207 0,07875103 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06438207 0,07871101 ! detection of light stimulus GO:0009583 38 29 0,000 0,06438207 0,07867103 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,06438207 0,0786311 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06438207 0,07859121 ! tissue homeostasis GO:0001894 48 29 0,000 0,06438207 0,07855135 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,06438207 0,07851154 ! phenol metabolic process GO:0018958 55 30 0,000 0,0665277 0,08108695 ! zinc ion transport GO:0006829 45 30 0,000 0,0665277 0,0810459 ! membrane docking GO:0022406 61 30 0,000 0,0665277 0,08100488 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0665277 0,08096391 ! cell junction assembly GO:0034329 78 30 0,000 0,0665277 0,08092298 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0665277 0,08088208 ! acute-phase response GO:0006953 49 30 0,000 0,0665277 0,08084124 ! myofibril assembly GO:0030239 47 30 0,000 0,0665277 0,08080043 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0665277 0,08075966 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0665277 0,08071893 ! phospholipid transport GO:0015914 51 30 0,000 0,0665277 0,08067825 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0665277 0,08063761 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0665277 0,080597 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0665277 0,08055644 ! eye morphogenesis GO:0048592 60 30 0,000 0,0665277 0,08051592 ! regulation of B cell activation GO:0050864 50 30 0,000 0,0665277 0,08047544 ! response to heat GO:0009408 50 30 0,000 0,0665277 0,080435 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06866848 0,0829816 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06866848 0,08293994 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06866848 0,08289832 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06866848 0,08285675 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06866848 0,08281522 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06866848 0,08277373 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06866848 0,08273228 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06866848 0,08269087 ! ovulation cycle process GO:0022602 49 31 0,000 0,06866848 0,0826495 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06866848 0,08260818 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06866848 0,0825669 ! peptide transport GO:0015833 55 31 0,000 0,06866848 0,08252565 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06866848 0,08248445 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06866848 0,08244329 ! mesoderm formation GO:0001707 69 31 0,000 0,06866848 0,08240217 ! natural killer cell activation GO:0030101 45 31 0,000 0,06866848 0,0823611 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06866848 0,08232006 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06866848 0,08227906 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06866848 0,08223811 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06866848 0,08219719 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06866848 0,08215632 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07080442 0,0846697 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07080442 0,08462763 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07080442 0,08458561 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07080442 0,08454364 ! cholesterol transport GO:0030301 56 32 0,000 0,07080442 0,0845017 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07080442 0,08445981 ! spliceosome assembly GO:0000245 67 32 0,000 0,07080442 0,08441795 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07080442 0,08437614 ! metanephros development GO:0001656 74 32 0,000 0,07080442 0,08433437 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07080442 0,08429264 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07080442 0,08425095 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,07080442 0,08420931 ! muscle cell development GO:0055001 49 32 0,000 0,07080442 0,0841677 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07080442 0,08412614 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07080442 0,08408461 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07080442 0,08404313 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07080442 0,08400169 ! ovulation cycle GO:0042698 51 32 0,000 0,07080442 0,08396029 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07080442 0,08391893 ! hindbrain development GO:0030902 61 32 0,000 0,07080442 0,08387761 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07080442 0,08383633 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07080442 0,0837951 ! gene silencing GO:0016458 65 32 0,000 0,07080442 0,0837539 ! post-embryonic development GO:0009791 69 33 0,000 0,07293553 0,08623237 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07293553 0,08619002 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07293553 0,08614771 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07293553 0,08610544 ! formation of primary germ layer GO:0001704 72 33 0,000 0,07293553 0,08606321 ! cell fate specification GO:0001708 52 33 0,000 0,07293553 0,08602102 ! sterol transport GO:0015918 57 33 0,000 0,07293553 0,08597887 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,07293553 0,08593677 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07293553 0,08589471 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07293553 0,08585268 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,07293553 0,0858107 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07293553 0,08576876 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07506182 0,08822606 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07506182 0,08818298 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07506182 0,08813995 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07506182 0,08809695 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07506182 0,088054 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07506182 0,08801109 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07506182 0,08796822 ! mismatch repair GO:0006298 46 34 0,000 0,07506182 0,08792539 ! spermatid development GO:0007286 63 34 0,000 0,07506182 0,0878826 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07506182 0,08783986 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07506182 0,08779716 ! placenta development GO:0001890 53 34 0,000 0,07506182 0,08775449 ! regulation of muscle development GO:0048634 70 35 0,000 0,07718331 0,09019089 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07718331 0,09014711 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07718331 0,09010337 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07718331 0,09005967 ! odontogenesis GO:0042476 66 35 0,000 0,07718331 0,09001602 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07718331 0,08997241 ! female gonad development GO:0008585 58 35 0,000 0,07718331 0,08992884 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,07718331 0,08988531 ! cytokine production GO:0001816 59 35 0,000 0,07718331 0,08984182 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,07718331 0,08979838 ! neural tube formation GO:0001841 67 35 0,000 0,07718331 0,08975498 ! vesicle localization GO:0051648 64 35 0,000 0,07718331 0,08971162 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0793 0,09212738 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0793 0,09208292 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0793 0,0920385 ! cell junction organization GO:0034330 86 36 0,000 0,0793 0,09199412 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0793 0,09194979 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0793 0,0919055 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0793 0,09186125 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0793 0,09181704 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0793 0,09177288 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0793 0,09172876 ! aerobic respiration GO:0009060 55 36 0,000 0,0793 0,09168468 ! embryonic organ development GO:0048568 57 36 0,000 0,0793 0,09164064 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0793 0,09159665 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08141191 0,09399091 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08141191 0,09394583 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08141191 0,0939008 ! organic anion transport GO:0015711 68 37 0,000 0,08141191 0,0938558 ! tissue remodeling GO:0048771 76 37 0,000 0,08141191 0,09381085 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08141191 0,09376595 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08141191 0,09372108 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08141191 0,09367626 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,08141191 0,09363148 ! pigment metabolic process GO:0042440 80 37 0,000 0,08141191 0,09358675 ! spermatid differentiation GO:0048515 66 37 0,000 0,08141191 0,09354205 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,08351905 0,09591734 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08351905 0,09587158 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08351905 0,09582586 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,08351905 0,09578018 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,08351905 0,09573455 ! lipid homeostasis GO:0055088 67 38 0,000 0,08351905 0,09568896 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,08351905 0,09564342 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08351905 0,09559792 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08351905 0,09555246 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08351905 0,09550705 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,08351905 0,09546167 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08562142 0,0978182 ! ear morphogenesis GO:0042471 60 39 0,000 0,08562142 0,09777177 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08562142 0,09772539 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08562142 0,09767906 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08562142 0,09763276 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08562142 0,09758651 ! RNA modification GO:0009451 57 39 0,000 0,08562142 0,09754031 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08562142 0,09749414 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08771903 0,09983538 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08771903 0,09978818 ! feeding behavior GO:0007631 59 40 0,000 0,08771903 0,09974102 ! negative regulation of binding GO:0051100 72 40 0,000 0,08771903 0,0996939 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08771903 0,09964683 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08771903 0,09959981 ! maintenance of protein location GO:0045185 91 40 0,000 0,08771903 0,09955283 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08981191 0,10187999 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08981191 0,10183197 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08981191 0,10178401 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08981191 0,10173609 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08981191 0,10168821 ! female gamete generation GO:0007292 61 41 0,000 0,08981191 0,10164038 ! polyol metabolic process GO:0019751 66 41 0,000 0,08981191 0,1015926 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08981191 0,10154485 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,09190005 0,10385699 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,09190005 0,10380823 ! regulation of tube size GO:0035150 71 42 0,000 0,09190005 0,10375951 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09190005 0,10371084 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,09190005 0,10366222 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09190005 0,10361365 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09190005 0,10356512 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,09190005 0,10351663 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09398347 0,10581387 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09398347 0,10576437 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09398347 0,10571493 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09398347 0,10566553 ! glucose transport GO:0015758 65 43 0,000 0,09398347 0,10561618 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09398347 0,10556687 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09398347 0,10551761 ! neural tube development GO:0021915 77 43 0,000 0,09398347 0,10546839 ! striated muscle contraction GO:0006941 77 43 0,000 0,09398347 0,10541922 ! phagocytosis GO:0006909 90 43 0,000 0,09398347 0,1053701 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09398347 0,10532102 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09606218 0,10760038 ! hexose transport GO:0008645 67 44 0,000 0,09606218 0,10755031 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09606218 0,10750028 ! male sex differentiation GO:0046661 76 44 0,000 0,09606218 0,10745031 ! biopolymer methylation GO:0043414 84 44 0,000 0,09606218 0,10740038 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09606218 0,10735049 ! developmental growth GO:0048589 82 44 0,000 0,09606218 0,10730065 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09606218 0,10725086 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09813619 0,10951562 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09813619 0,10946485 ! leukocyte migration GO:0050900 68 45 0,000 0,09813619 0,10941412 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09813619 0,10936345 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09813619 0,10931281 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09813619 0,10926223 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09813619 0,10921169 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09813619 0,1091612 ! cell growth GO:0016049 84 45 0,000 0,09813619 0,10911076 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,10020551 0,11136003 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10020551 0,11130862 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,10020551 0,11125725 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10020551 0,11120593 ! pigmentation GO:0043473 100 46 0,000 0,10020551 0,11115466 ! positive regulation of defense response GO:0031349 76 47 0,000 0,10227015 0,11339262 ! response to calcium ion GO:0051592 81 47 0,000 0,10227015 0,11334039 ! endosome transport GO:0016197 108 47 0,000 0,10227015 0,11328821 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,10227015 0,11323607 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,10227015 0,11318399 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,10227015 0,11313195 ! JNK cascade GO:0007254 91 47 0,000 0,10227015 0,11307996 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,10227015 0,11302802 ! methylation GO:0032259 90 47 0,000 0,10227015 0,11297612 ! protein homooligomerization GO:0051260 76 47 0,000 0,10227015 0,11292427 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10433013 0,115146 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10433013 0,11509321 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,10433013 0,11504046 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10433013 0,11498776 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10433013 0,11493511 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10433013 0,11488251 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10638544 0,11709212 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10638544 0,11703858 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10638544 0,11698509 ! regulation of ion transport GO:0043269 77 49 0,000 0,10638544 0,11693164 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10638544 0,11687825 ! peptide metabolic process GO:0006518 76 49 0,000 0,10638544 0,11682491 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10638544 0,11677161 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10638544 0,11671836 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10638544 0,11666516 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10638544 0,11661201 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10638544 0,11655891 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10638544 0,11650586 ! neuromuscular process GO:0050905 99 50 0,000 0,1084361 0,11869757 ! regulation of ossification GO:0030278 117 50 0,000 0,1084361 0,1186436 ! inner ear development GO:0048839 79 50 0,000 0,1084361 0,11858967 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,1084361 0,11853579 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,1084361 0,11848196 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,11048213 0,12066274 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,11048213 0,12060799 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,11048213 0,12055329 ! excretion GO:0007588 83 51 0,000 0,11048213 0,12049864 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,11048213 0,12044405 ! chromatin remodeling GO:0006338 109 51 0,000 0,11048213 0,1203895 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,11048213 0,120335 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,11048213 0,12028055 ! vesicle organization GO:0016050 107 51 0,000 0,11048213 0,12022615 ! regulation of cell shape GO:0008360 125 51 0,000 0,11048213 0,12017179 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,11048213 0,12011749 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,11252353 0,12228167 ! membrane fusion GO:0006944 110 52 0,000 0,11252353 0,12222646 ! amino acid activation GO:0043038 92 52 0,000 0,11252353 0,12217131 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,11252353 0,1221162 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11456032 0,12427057 ! RNA catabolic process GO:0006401 93 53 0,000 0,11456032 0,12421456 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11456032 0,12415861 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11456032 0,12410271 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11456032 0,12404686 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11456032 0,12399106 ! cell maturation GO:0048469 100 53 0,000 0,11456032 0,1239353 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,11456032 0,1238796 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,11659249 0,12602046 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11659249 0,12596387 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11659249 0,12590733 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11659249 0,12585084 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11659249 0,12579441 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11659249 0,12573802 ! chloride transport GO:0006821 90 55 0,000 0,11862007 0,12786733 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11862007 0,12781007 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,11862007 0,12775286 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11862007 0,1276957 ! gastrulation GO:0007369 112 55 0,000 0,11862007 0,12763859 ! RNA elongation GO:0006354 79 55 0,000 0,11862007 0,12758153 ! nuclear export GO:0051168 97 55 0,000 0,11862007 0,12752453 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11862007 0,12746757 ! regulation of actin filament length GO:0030832 105 56 0,000 0,12064306 0,12958358 ! sensory perception of smell GO:0007608 80 56 0,000 0,12064306 0,12952575 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,12064306 0,12946798 ! proton transport GO:0015992 94 56 0,000 0,12064306 0,12941026 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,12266148 0,13151672 ! lipid modification GO:0030258 97 57 0,000 0,12266148 0,13145814 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,12266148 0,13139961 ! maintenance of location GO:0051235 118 57 0,000 0,12266148 0,13134113 ! hydrogen transport GO:0006818 97 58 0,000 0,12467533 0,1334381 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,12467533 0,13337877 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12467533 0,13331949 ! adult behavior GO:0030534 99 58 0,000 0,12467533 0,13326026 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,12467533 0,13320109 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12668463 0,13528771 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12668463 0,13522769 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12668463 0,13516772 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,12668463 0,13510781 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,12668463 0,13504794 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12868938 0,13712429 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12868938 0,13706358 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12868938 0,13700294 ! camera-type eye development GO:0043010 116 60 0,000 0,12868938 0,13694234 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12868938 0,1368818 ! kidney development GO:0001822 122 60 0,000 0,12868938 0,13682132 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,13068959 0,13888655 ! mesoderm development GO:0007498 119 61 0,000 0,13068959 0,13882523 ! tRNA processing GO:0008033 89 61 0,000 0,13068959 0,13876397 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,13068959 0,13870276 ! ear development GO:0043583 103 62 0,000 0,13268528 0,14075872 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13268528 0,14069669 ! gonad development GO:0008406 98 62 0,000 0,13268528 0,1406347 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,13268528 0,14057278 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13467645 0,14261952 ! detection of external stimulus GO:0009581 91 63 0,000 0,13467645 0,14255677 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13467645 0,14249408 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13666312 0,14453251 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13666312 0,14446901 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,13666312 0,14440556 ! single fertilization GO:0007338 75 64 0,000 0,13666312 0,14434217 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13864529 0,14637147 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13864529 0,14630727 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13864529 0,14624313 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,13864529 0,14617904 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,14062298 0,14819925 ! actin filament organization GO:0007015 148 66 0,000 0,14062298 0,14813437 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,14062298 0,14806954 ! extracellular matrix organization GO:0030198 133 66 0,000 0,14062298 0,14800476 ! secondary metabolic process GO:0019748 116 66 0,000 0,14062298 0,14794005 ! developmental maturation GO:0021700 116 66 0,000 0,14062298 0,14787539 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,14259619 0,14988486 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,14259619 0,14981941 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,14259619 0,14975401 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,14259619 0,14968867 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,14259619 0,14962339 ! adaptive immune response GO:0002250 119 67 0,000 0,14259619 0,14955817 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,14259619 0,149493 ! amino acid transport GO:0006865 125 68 0,000 0,14456494 0,15149096 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14456494 0,15142501 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14456494 0,15135912 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,14456494 0,15129328 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,14456494 0,1512275 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14456494 0,15116178 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14652923 0,15314915 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14652923 0,15308265 ! urogenital system development GO:0001655 137 69 0,000 0,14652923 0,1530162 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14652923 0,15294982 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14652923 0,15288349 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14652923 0,15281722 ! appendage morphogenesis GO:0035107 135 70 0,000 0,14848908 0,15479408 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,15044449 0,15676459 ! reproductive structure development GO:0048608 113 71 0,000 0,15044449 0,15669673 ! appendage development GO:0048736 136 71 0,000 0,15044449 0,15662893 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,15044449 0,15656118 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,15044449 0,15649349 ! regulation of immune effector process GO:0002697 137 71 0,000 0,15044449 0,15642586 ! acute inflammatory response GO:0002526 113 72 0,000 0,15239548 0,15838597 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,15239548 0,15831758 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,15239548 0,15824925 ! carbohydrate transport GO:0008643 110 72 0,000 0,15239548 0,15818098 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,15239548 0,15811277 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,15239548 0,15804462 ! regulation of blood pressure GO:0008217 125 73 0,000 0,15434205 0,15999439 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15434205 0,15992548 ! fertilization GO:0009566 90 73 0,000 0,15434205 0,15985664 ! transition metal ion transport GO:0000041 126 74 0,000 0,15628421 0,16179854 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15628421 0,16172895 ! exocytosis GO:0006887 133 74 0,000 0,15628421 0,16165942 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15628421 0,16158995 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,15628421 0,16152054 ! eye development GO:0001654 143 74 0,000 0,15628421 0,16145119 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,15822198 0,16338287 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15822198 0,16331278 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15822198 0,16324275 ! rhythmic process GO:0048511 128 75 0,000 0,15822198 0,16317278 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,16015536 0,16509589 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,16015536 0,16502519 ! defense response to bacterium GO:0042742 89 76 0,000 0,16015536 0,16495454 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,16015536 0,16488396 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,16208437 0,16679854 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,16208437 0,16672723 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,16208437 0,16665598 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,16208437 0,16658479 ! blood coagulation GO:0007596 146 78 0,000 0,16400901 0,1684909 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,16400901 0,16841898 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,16400901 0,16834713 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,16592929 0,17024558 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,16592929 0,17017301 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,16592929 0,1701005 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,16592929 0,17002806 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16784523 0,1719181 ! response to metal ion GO:0010038 140 80 0,000 0,16784523 0,17184495 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16784523 0,17177185 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16784523 0,17169882 ! inorganic anion transport GO:0015698 138 80 0,000 0,16784523 0,17162585 ! digestion GO:0007586 112 81 0,000 0,16975683 0,17350677 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16975683 0,17343309 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16975683 0,17335948 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,1716641 0,17523285 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,1716641 0,17515853 ! response to nutrient GO:0007584 125 82 0,000 0,1716641 0,17508428 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,1716641 0,17501009 ! regulation of lyase activity GO:0051339 160 83 0,000 0,17356705 0,17687519 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,1754657 0,17873432 ! hemostasis GO:0007599 158 84 0,000 0,1754657 0,17865868 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1754657 0,17858311 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,1754657 0,1785076 ! response to unfolded protein GO:0006986 131 85 0,000 0,17736004 0,18035852 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17736004 0,18028232 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,17736004 0,18020619 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,1792501 0,1820497 ! response to inorganic substance GO:0010035 153 86 0,000 0,1792501 0,18197288 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,1792501 0,18189613 ! amine transport GO:0015837 155 86 0,000 0,1792501 0,18181945 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,18113587 0,18365483 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,18113587 0,18357747 ! cellular respiration GO:0045333 135 88 0,000 0,18301738 0,18540624 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,18301738 0,1853282 ! regulation of neurological system process GO:0031644 148 88 0,000 0,18301738 0,18525024 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,18301738 0,18517233 ! cellular defense response GO:0006968 114 89 0,000 0,18489462 0,18699305 ! ossification GO:0001503 188 90 0,000 0,18676762 0,18880794 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18676762 0,18872864 ! sex differentiation GO:0007548 145 90 0,000 0,18676762 0,18864941 ! bone development GO:0060348 189 91 0,000 0,18863637 0,19045703 ! sterol metabolic process GO:0016125 152 91 0,000 0,18863637 0,19037714 ! response to protein stimulus GO:0051789 149 91 0,000 0,18863637 0,19029732 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18863637 0,19021756 ! regulation of defense response GO:0031347 149 92 0,000 0,19050089 0,19201724 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,19050089 0,19193683 ! vitamin metabolic process GO:0006766 139 92 0,000 0,19050089 0,19185649 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,19236119 0,19364896 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,19236119 0,19356797 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,19236119 0,19348705 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,19421727 0,19527236 ! female pregnancy GO:0007565 164 94 0,000 0,19421727 0,19519079 ! transcription initiation GO:0006352 153 94 0,000 0,19421727 0,19510929 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,19606915 0,19688747 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,19791684 0,19865996 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,19791684 0,19857711 ! positive regulation of immune response GO:0050778 156 96 0,000 0,19791684 0,19849434 ! detection of stimulus GO:0051606 151 96 0,000 0,19791684 0,19841163 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19976034 0,20017633 ! protein ubiquitination GO:0016567 217 97 0,000 0,19976034 0,200093 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,20159967 0,20185135 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,20159967 0,20176739 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,20343482 0,20351941 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,20343482 0,20343482