pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6209-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of transport GO:0051051 116 73 6,000 2,409E-06 5,54E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,909E-05 0,02195444 ! positive regulation of locomotion GO:0040017 35 20 3,000 1,984E-05 0,01520985 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 3,000 1,984E-05 0,01140739 ! regulation of chemotaxis GO:0050920 36 21 3,000 2,435E-05 0,01120069 ! regulation of behavior GO:0050795 38 22 3,000 2,957E-05 0,01133477 ! induction of positive chemotaxis GO:0050930 14 8 2,000 3,036E-05 9,975E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 4,24E-05 0,01219072 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 4,526E-05 0,01156701 ! positive regulation of T cell differentiation GO:0045582 39 28 3,000 7,963E-05 0,01831389 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 8,783E-05 0,01836453 GO:0050927|positive regulation of positive chemotaxis, ! chondrocyte differentiation GO:0002062 17 11 2,000 8,783E-05 0,01683415 ! negative regulation of glucose import GO:0046325 14 11 2,000 8,783E-05 0,01553922 GO:0010829|negative regulation of glucose transport, ! metanephros development GO:0001656 58 31 3,000 1,2E-04 0,01971828 ! leukocyte chemotaxis GO:0030595 43 31 3,000 1,2E-04 0,01840373 GO:0060326|cell chemotaxis, ! positive regulation of lymphocyte differentiation GO:0045621 45 32 3,000 1,363E-04 0,01959181 ! cell-matrix adhesion GO:0007160 114 61 4,000 1,5E-04 0,02029429 ! urogenital system development GO:0001655 101 61 4,000 1,5E-04 0,01916683 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,504E-04 0,01820577 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 1,735E-04 0,01995497 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 4,000 1,749E-04 0,01915426 ! cell-substrate adhesion GO:0031589 121 66 4,000 2,18E-04 0,02278863 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 2,000 2,364E-04 0,02363699 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 2,364E-04 0,02265211 ! positive regulation of phosphorylation GO:0042327 102 70 4,000 2,875E-04 0,02644735 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 2,000 2,892E-04 0,02557883 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,892E-04 0,02463147 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 3,279E-04 0,02693873 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 3,29E-04 0,02609416 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 3,29E-04 0,02522435 ! signal complex assembly GO:0007172 29 17 2,000 3,49E-04 0,02589236 ! inactivation of MAPK activity GO:0000188 27 17 2,000 3,49E-04 0,02508323 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 3,49E-04 0,02432313 ! negative regulation of intracellular transport GO:0032387 29 17 2,000 3,49E-04 0,02360774 ! tube morphogenesis GO:0035239 118 73 4,000 3,497E-04 0,02298276 ! regulation of T cell differentiation GO:0045580 59 41 3,000 3,622E-04 0,02314368 ! regulation of glucose import GO:0046324 21 18 2,000 4,162E-04 0,02587452 GO:0010827|regulation of glucose transport, ! leukocyte migration GO:0050900 60 43 3,000 4,358E-04 0,02637824 ! response to insulin stimulus GO:0032868 63 43 3,000 4,358E-04 0,02570188 ! epithelial tube morphogenesis GO:0060562 65 43 3,000 4,358E-04 0,02505933 ! regulation of inflammatory response GO:0050727 60 44 3,000 4,763E-04 0,02672094 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 4,913E-04 0,02690412 ! positive regulation of defense response GO:0031349 59 45 3,000 5,195E-04 0,02778498 ! cellular aldehyde metabolic process GO:0006081 29 20 2,000 5,745E-04 0,03003018 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,745E-04 0,02936284 ! positive regulation of B cell activation GO:0050871 31 20 2,000 5,745E-04 0,02872452 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 6,655E-04 0,03256521 ! cell aging GO:0007569 32 21 2,000 6,662E-04 0,03192115 ! sleep GO:0030431 11 5 1,000 6,721E-04 0,0315489 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 6,721E-04 0,03091793 ! rhythmic behavior GO:0007622 12 5 1,000 6,721E-04 0,03031169 ! response to protozoan GO:0001562 9 5 1,000 6,721E-04 0,02972877 ! positive regulation of glycolysis GO:0045821 11 5 1,000 6,721E-04 0,02916785 ! neutrophil mediated immunity GO:0002446 6 5 1,000 6,721E-04 0,02862771 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 1,000 6,721E-04 0,02810721 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 1,000 6,721E-04 0,02760529 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 1,000 6,721E-04 0,02712099 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 6,721E-04 0,02665338 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 6,721E-04 0,02620163 GO:0045686|negative regulation of glial cell differentiation, ! positive regulation of organ growth GO:0046622 6 5 1,000 6,721E-04 0,02576494 ! positive regulation of chemokine production GO:0032722 7 5 1,000 6,721E-04 0,02534256 ! enteric nervous system development GO:0048484 8 5 1,000 6,721E-04 0,02493381 ! regulation of respiratory burst GO:0060263 8 5 1,000 6,721E-04 0,02453804 ! carnitine metabolic process GO:0009437 5 5 1,000 6,721E-04 0,02415463 GO:0006577|betaine metabolic process, ! integrin-mediated signaling pathway GO:0007229 81 49 3,000 7,2E-04 0,02547645 ! spliceosomal snRNP biogenesis GO:0000387 28 22 2,000 7,667E-04 0,02671827 ! ureteric bud development GO:0001657 32 22 2,000 7,667E-04 0,02631949 ! positive regulation of cell migration GO:0030335 92 51 3,000 8,384E-04 0,02835722 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 8,764E-04 0,02921227 ! kidney development GO:0001822 90 53 3,000 9,699E-04 0,03186802 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 1,000 1,003E-03 0,032482 GO:0045346|regulation of MHC class II biosynthetic process, ! prostate gland development GO:0030850 9 6 1,000 1,003E-03 0,03203086 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 1,003E-03 0,03159209 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,003E-03 0,03116517 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 1,003E-03 0,03074963 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 1,003E-03 0,03034503 ! male sex determination GO:0030238 9 6 1,000 1,003E-03 0,02995094 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 1,003E-03 0,02956695 ! regulation of collagen metabolic process GO:0010712 7 6 1,000 1,003E-03 0,02919269 ! neutrophil homeostasis GO:0001780 6 6 1,000 1,003E-03 0,02882778 ! salivary gland morphogenesis GO:0007435 11 6 1,000 1,003E-03 0,02847188 ! organ or tissue specific immune response GO:0002251 7 6 1,000 1,003E-03 0,02812466 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 1,124E-03 0,03115856 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of cell motion GO:0051272 99 56 3,000 1,193E-03 0,03267668 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 1,263E-03 0,0341861 ! negative regulation of protein modification process GO:0031400 50 26 2,000 1,263E-03 0,03378858 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,275E-03 0,03371471 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 1,275E-03 0,03333159 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,361E-03 0,03517273 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,396E-03 0,03567942 ! protein heterooligomerization GO:0051291 10 7 1,000 1,396E-03 0,03528734 ! T cell lineage commitment GO:0002360 12 7 1,000 1,396E-03 0,03490378 ! neuroblast proliferation GO:0007405 13 7 1,000 1,396E-03 0,03452847 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 1,396E-03 0,03416114 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 1,000 1,396E-03 0,03380155 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,396E-03 0,03344945 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 1,396E-03 0,03310461 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 1,396E-03 0,03276681 ! negative regulation of protein transport GO:0051224 49 27 2,000 1,413E-03 0,03282118 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,573E-03 0,03617236 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,573E-03 0,03581421 ! regulation of B cell activation GO:0050864 42 28 2,000 1,573E-03 0,03546309 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,642E-03 0,03667245 ! tissue homeostasis GO:0001894 42 29 2,000 1,744E-03 0,03856013 GO:0048871|multicellular organismal homeostasis, ! regulation of transcription factor activity GO:0051090 97 63 3,000 1,851E-03 0,04054083 GO:0090046|regulation of transcription regulator activity, ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,851E-03 0,04017221 ! pseudouridine synthesis GO:0001522 9 8 1,000 1,851E-03 0,03979677 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,851E-03 0,03942828 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 1,000 1,851E-03 0,03906655 ! Schwann cell differentiation GO:0014037 17 8 1,000 1,851E-03 0,0387114 ! regulation of gliogenesis GO:0014013 20 8 1,000 1,851E-03 0,03836265 GO:0045685|regulation of glial cell differentiation, ! segment specification GO:0007379 10 8 1,000 1,851E-03 0,03802013 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,851E-03 0,03768367 ! myeloid cell homeostasis GO:0002262 8 8 1,000 1,851E-03 0,03735311 ! regulation of embryonic development GO:0045995 16 8 1,000 1,851E-03 0,0370283 ! embryonic epithelial tube formation GO:0001838 44 30 2,000 1,926E-03 0,0381806 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 1,962E-03 0,03856135 ! positive regulation of T cell activation GO:0050870 94 65 3,000 2,077E-03 0,04048253 ! negative regulation of secretion GO:0051048 49 31 2,000 2,119E-03 0,04095717 ! segmentation GO:0035282 41 31 2,000 2,119E-03 0,04061586 ! regulation of developmental growth GO:0048638 13 9 1,000 2,367E-03 0,04500128 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,367E-03 0,04463242 ! regulation of glycolysis GO:0006110 15 9 1,000 2,367E-03 0,04426955 ! myeloid leukocyte mediated immunity GO:0002444 11 9 1,000 2,367E-03 0,04391254 ! epithelial cell development GO:0002064 10 9 1,000 2,367E-03 0,04356124 ! regulation of RNA splicing GO:0043484 14 9 1,000 2,367E-03 0,04321551 ! blastocyst formation GO:0001825 12 9 1,000 2,367E-03 0,04287524 ! pyrimidine base metabolic process GO:0006206 14 9 1,000 2,367E-03 0,04254027 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 2,367E-03 0,0422105 ! defense response to Gram-positive bacterium GO:0050830 10 9 1,000 2,367E-03 0,04188581 ! embryonic placenta development GO:0001892 12 9 1,000 2,367E-03 0,04156607 ! localization within membrane GO:0051668 15 9 1,000 2,367E-03 0,04125117 ! carbohydrate homeostasis GO:0033500 39 33 2,000 2,541E-03 0,04394584 GO:0042593|glucose homeostasis, ! thyroid gland development GO:0030878 19 10 1,000 2,943E-03 0,05051858 ! regulation of B cell proliferation GO:0030888 15 10 1,000 2,943E-03 0,05014437 ! hippocampus development GO:0021766 19 10 1,000 2,943E-03 0,04977566 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,943E-03 0,04941234 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,943E-03 0,04905427 ! neurotransmitter biosynthetic process GO:0042136 14 10 1,000 2,943E-03 0,04870137 ! regulation of organ growth GO:0046620 11 10 1,000 2,943E-03 0,0483535 ! positive regulation of interleukin-6 production GO:0032755 13 10 1,000 2,943E-03 0,04801057 ! cranial nerve development GO:0021545 12 10 1,000 2,943E-03 0,04767246 ! salivary gland development GO:0007431 22 10 1,000 2,943E-03 0,04733909 ! positive regulation of acute inflammatory response GO:0002675 14 10 1,000 2,943E-03 0,04701035 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 2,943E-03 0,04668614 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 2,943E-03 0,04636637 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of intracellular protein transport GO:0033157 59 35 2,000 3,012E-03 0,0471237 ! positive regulation of leukocyte proliferation GO:0070665 50 35 2,000 3,012E-03 0,0468053 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 2,000 3,266E-03 0,0504123 GO:0090047|positive regulation of transcription regulator activity, ! cellular response to hormone stimulus GO:0032870 109 74 3,000 3,333E-03 0,05110489 ! positive regulation of lymphocyte activation GO:0051251 108 74 3,000 3,333E-03 0,05076645 ! virus-host interaction GO:0019048 17 11 1,000 3,578E-03 0,0541377 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,578E-03 0,05378386 ! bone resorption GO:0045453 16 11 1,000 3,578E-03 0,05343461 ! regulation of mRNA processing GO:0050684 18 11 1,000 3,578E-03 0,05308987 ! focal adhesion formation GO:0048041 24 11 1,000 3,578E-03 0,05274955 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 3,578E-03 0,05241357 ! regulation of leukocyte migration GO:0002685 24 11 1,000 3,578E-03 0,05208184 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 3,578E-03 0,05175428 ! regulation of protein transport GO:0051223 114 76 3,000 3,669E-03 0,05274591 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 3,000 3,846E-03 0,05493983 ! gland development GO:0048732 148 77 3,000 3,846E-03 0,0546007 ! positive regulation of protein modification process GO:0031401 107 78 3,000 4,028E-03 0,0568363 ! morphogenesis of embryonic epithelium GO:0016331 60 39 2,000 4,105E-03 0,0575729 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 4,105E-03 0,05722397 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 4,27E-03 0,0591637 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 4,27E-03 0,05880942 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 4,27E-03 0,05845937 ! autonomic nervous system development GO:0048483 23 12 1,000 4,27E-03 0,05811346 ! gland morphogenesis GO:0022612 23 12 1,000 4,27E-03 0,05777161 ! peptidyl-lysine modification GO:0018205 18 12 1,000 4,27E-03 0,05743377 ! positive regulation of cell activation GO:0050867 120 81 3,000 4,609E-03 0,06163647 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of DNA binding GO:0043388 57 41 2,000 4,731E-03 0,06289826 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 5,019E-03 0,06634454 ! regulation of chemokine production GO:0032642 17 13 1,000 5,019E-03 0,06596542 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 1,000 5,019E-03 0,06559062 ! endocrine pancreas development GO:0031018 19 13 1,000 5,019E-03 0,06522005 ! exocrine system development GO:0035272 27 13 1,000 5,019E-03 0,06485365 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 5,019E-03 0,06449134 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 5,019E-03 0,06413305 ! regulation of acute inflammatory response GO:0002673 19 13 1,000 5,019E-03 0,06377872 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 5,019E-03 0,06342829 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 5,064E-03 0,06365053 ! branching morphogenesis of a tube GO:0048754 72 42 2,000 5,064E-03 0,0633046 ! regulation of defense response GO:0031347 117 84 3,000 5,245E-03 0,0652044 ! positive regulation of binding GO:0051099 59 43 2,000 5,412E-03 0,06691652 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 5,412E-03 0,06655867 ! regulation of protein localization GO:0032880 132 85 3,000 5,469E-03 0,06690631 ! cell cycle arrest GO:0007050 150 86 3,000 5,699E-03 0,06935709 ! glycolysis GO:0006096 53 44 2,000 5,773E-03 0,06987909 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,773E-03 0,06951323 ! ribonucleoprotein complex assembly GO:0022618 70 44 2,000 5,773E-03 0,06915118 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 5,773E-03 0,06879288 ! neuron maturation GO:0042551 21 14 1,000 5,824E-03 0,06904645 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 5,824E-03 0,06869237 ! limbic system development GO:0021761 25 14 1,000 5,824E-03 0,0683419 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 5,824E-03 0,06799498 GO:0060675|ureteric bud morphogenesis, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 5,824E-03 0,06765157 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 5,824E-03 0,06731162 ! peptide hormone secretion GO:0030072 23 14 1,000 5,824E-03 0,06697506 ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 5,936E-03 0,06792687 ! cell maturation GO:0048469 60 45 2,000 6,148E-03 0,07000023 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 6,148E-03 0,0696554 ! regulation of T cell activation GO:0050863 128 89 3,000 6,429E-03 0,07248897 ! negative regulation of hormone secretion GO:0046888 20 15 1,000 6,684E-03 0,07498607 ! lipid phosphorylation GO:0046834 23 15 1,000 6,684E-03 0,07462206 ! peptide secretion GO:0002790 27 15 1,000 6,684E-03 0,07426156 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 6,684E-03 0,07390454 ! defense response to virus GO:0051607 27 15 1,000 6,684E-03 0,07355093 ! endocrine system development GO:0035270 83 47 2,000 6,941E-03 0,07602261 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 2,000 6,941E-03 0,07566231 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 6,941E-03 0,07530541 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 69 48 2,000 7,36E-03 0,07946961 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 7,597E-03 0,08165027 ! hormone secretion GO:0046879 25 16 1,000 7,597E-03 0,0812705 ! bone remodeling GO:0046849 24 16 1,000 7,597E-03 0,08089425 ! protein amino acid acetylation GO:0006473 28 16 1,000 7,597E-03 0,08052146 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 7,597E-03 0,0801521 ! neural crest cell migration GO:0001755 24 16 1,000 7,597E-03 0,07978611 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 7,597E-03 0,07942344 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 7,597E-03 0,07906406 ! nerve development GO:0021675 18 16 1,000 7,597E-03 0,07870792 ! RNA elongation GO:0006354 62 49 2,000 7,793E-03 0,08037204 ! regulation of intracellular transport GO:0032386 78 49 2,000 7,793E-03 0,08001323 ! morphogenesis of a branching structure GO:0001763 86 49 2,000 7,793E-03 0,07965762 ! cartilage development GO:0051216 70 49 2,000 7,793E-03 0,07930515 ! regulation of binding GO:0051098 151 95 3,000 8,07E-03 0,08177031 ! positive regulation of growth GO:0045927 67 50 2,000 8,24E-03 0,08312643 ! regulation of response to external stimulus GO:0032101 139 96 3,000 8,368E-03 0,08404656 ! cell-substrate junction assembly GO:0007044 39 17 1,000 8,563E-03 0,0856343 ! actin filament bundle formation GO:0051017 26 17 1,000 8,563E-03 0,08526359 ! nucleobase metabolic process GO:0009112 31 17 1,000 8,563E-03 0,08489608 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 8,563E-03 0,08453172 ! aging GO:0007568 79 52 2,000 9,181E-03 0,09023633 ! positive regulation of DNA replication GO:0045740 29 18 1,000 9,582E-03 0,0937796 ! positive regulation of translation GO:0045727 28 18 1,000 9,582E-03 0,09338223 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 9,582E-03 0,09298821 ! pancreas development GO:0031016 26 18 1,000 9,582E-03 0,09259751 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 9,582E-03 0,09221007 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 1,000 9,582E-03 0,09182586 ! somitogenesis GO:0001756 24 18 1,000 9,582E-03 0,09144484 ! hormone transport GO:0009914 27 18 1,000 9,582E-03 0,09106697 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 9,582E-03 0,09069221 ! gut development GO:0048565 26 18 1,000 9,582E-03 0,09032052 ! glucose catabolic process GO:0006007 66 54 2,000 0,01018099 0,09557668 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 0,0106513 0,09958536 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 0,0106513 0,09918218 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 0,0106513 0,09878225 ! sex determination GO:0007530 29 19 1,000 0,0106513 0,09838554 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 1,000 0,0106513 0,09799199 ! regulation of interleukin-6 production GO:0032675 22 19 1,000 0,0106513 0,09760159 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 0,01124235 0,10260877 ! neurotransmitter metabolic process GO:0042133 30 20 1,000 0,01177095 0,10700863 ! pallium development GO:0021543 38 20 1,000 0,01177095 0,10658734 ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 0,01177095 0,10616935 ! developmental maturation GO:0021700 75 57 2,000 0,01179608 0,10598039 ! gluconeogenesis GO:0006094 25 21 1,000 0,01293987 0,11580431 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01293987 0,11535545 ! regulation of DNA recombination GO:0000018 40 21 1,000 0,01293987 0,11491007 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 0,01293987 0,1144681 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 0,01293987 0,11402953 ! platelet activation GO:0030168 28 21 1,000 0,01293987 0,1135943 ! positive regulation of protein secretion GO:0050714 26 21 1,000 0,01293987 0,11316239 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 0,01293987 0,11273374 ! lung development GO:0030324 94 59 2,000 0,01294997 0,11239597 ! actin filament organization GO:0007015 95 59 2,000 0,01294997 0,11197343 ! regulation of heart contraction GO:0008016 91 60 2,000 0,01355026 0,1167251 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 0,01415719 0,12149827 ! vasculogenesis GO:0001570 33 22 1,000 0,01415719 0,12104661 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01415719 0,12059829 ! blastocyst development GO:0001824 37 22 1,000 0,01415719 0,12015327 ! neural tube closure GO:0001843 33 22 1,000 0,01415719 0,11971153 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 1,000 0,01415719 0,11927303 ! homeostasis of number of cells GO:0048872 84 61 2,000 0,01416619 0,11891328 ! respiratory tube development GO:0030323 99 62 2,000 0,01479781 0,12376349 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01542203 0,12851692 ! embryonic pattern specification GO:0009880 31 23 1,000 0,01542203 0,12805296 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01542203 0,12759234 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 0,01542203 0,12713502 ! interaction with host GO:0051701 37 23 1,000 0,01542203 0,12668096 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01542203 0,12623014 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 0,01542203 0,12578252 ! hexose catabolic process GO:0019320 82 64 2,000 0,01610829 0,1309154 ! respiratory system development GO:0060541 100 64 2,000 0,01610829 0,13045443 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01673353 0,13504254 ! pyruvate metabolic process GO:0006090 29 24 1,000 0,01673353 0,13457037 ! neural crest cell development GO:0014032 39 24 1,000 0,01673353 0,13410148 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 1,000 0,01673353 0,13363585 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01673353 0,13317344 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01673353 0,13271422 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01673353 0,13225816 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 0,01673353 0,13180522 ! peptide transport GO:0015833 43 25 1,000 0,01809085 0,14201006 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,01809085 0,14152703 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 0,01809085 0,14104728 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01949313 0,15146692 ! circadian rhythm GO:0007623 42 26 1,000 0,01949313 0,15095693 ! humoral immune response GO:0006959 86 70 2,000 0,02042003 0,15760427 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 0,02042003 0,15707716 ! regulation of catabolic process GO:0009894 106 70 2,000 0,02042003 0,15655357 ! acute-phase response GO:0006953 42 27 1,000 0,02093957 0,16000333 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,02093957 0,15947352 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,02093957 0,1589472 ! monosaccharide catabolic process GO:0046365 91 71 2,000 0,02119435 0,160352 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,02242932 0,16913916 ! cell junction assembly GO:0034329 56 28 1,000 0,02242932 0,16858642 ! mesoderm formation GO:0001707 46 28 1,000 0,02242932 0,16803728 ! neural tube formation GO:0001841 41 28 1,000 0,02242932 0,16749171 ! placenta development GO:0001890 37 28 1,000 0,02242932 0,16694966 ! protein import into nucleus GO:0006606 118 74 2,000 0,023613 0,17519323 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 0,0239616 0,17720798 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,0239616 0,17664001 ! formation of primary germ layer GO:0001704 48 29 1,000 0,0239616 0,17607566 ! telencephalon development GO:0021537 52 29 1,000 0,0239616 0,17551491 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,0239616 0,17495772 ! nuclear import GO:0051170 121 75 2,000 0,02445111 0,17796694 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 0,0255356 0,18527406 ! spliceosome assembly GO:0000245 49 30 1,000 0,0255356 0,18469144 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,02715053 0,19575617 ! glial cell differentiation GO:0010001 55 31 1,000 0,02715053 0,19514444 ! mesoderm morphogenesis GO:0048332 49 31 1,000 0,02715053 0,19453651 ! cell fate specification GO:0001708 37 31 1,000 0,02715053 0,19393236 ! RNA modification GO:0009451 40 31 1,000 0,02715053 0,19333195 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02880562 0,20448433 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02880562 0,20385515 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02880562 0,20322983 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,02880562 0,20260833 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02880562 0,20199062 ! alcohol catabolic process GO:0046164 104 80 2,000 0,02888046 0,20189984 ! protein localization in nucleus GO:0034504 133 80 2,000 0,02888046 0,20128802 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,02981396 0,20716649 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,0305001 0,21129585 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,0305001 0,21066133 ! cell junction organization GO:0034330 63 33 1,000 0,0305001 0,2100306 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,0305001 0,20940365 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,03223321 0,22064397 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,03223321 0,21998924 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 0,03223321 0,21933838 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,03223321 0,21869137 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 0,03370588 0,2280104 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,03370588 0,22734174 ! transcription initiation GO:0006352 118 85 2,000 0,03370588 0,226677 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,03370588 0,22601614 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 0,03471817 0,23212729 ! response to reactive oxygen species GO:0000302 55 36 1,000 0,03581234 0,23874892 ! regulation of hormone secretion GO:0046883 48 36 1,000 0,03581234 0,23805889 ! tissue remodeling GO:0048771 62 36 1,000 0,03581234 0,23737284 ! neural tube development GO:0021915 50 36 1,000 0,03581234 0,23669074 ! anatomical structure homeostasis GO:0060249 136 88 2,000 0,03678962 0,24245309 ! interphase GO:0051325 159 88 2,000 0,03678962 0,24176036 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,03765689 0,24675457 ! regulation of protein secretion GO:0050708 51 37 1,000 0,03765689 0,24605356 ! reproductive developmental process GO:0003006 127 89 2,000 0,0378487 0,24660624 ! hormone metabolic process GO:0042445 121 90 2,000 0,03892327 0,25289132 ! gliogenesis GO:0042063 71 38 1,000 0,03953715 0,25615616 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,03953715 0,25543662 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,03953715 0,25472111 ! mesenchymal cell development GO:0014031 64 38 1,000 0,03953715 0,2540096 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,04079355 0,26135146 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,04079355 0,26062549 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,04079355 0,25990353 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,04079355 0,25918557 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,04079355 0,25847156 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04079355 0,25776147 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,04079355 0,25705528 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,04079355 0,25635294 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,04079355 0,25565443 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,04079355 0,25495972 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,04079355 0,25426877 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,04079355 0,25358156 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,04079355 0,25289805 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,04079355 0,25221821 ! tongue development GO:0043586 6 5 0,000 0,04079355 0,25154203 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,04079355 0,25086945 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,04079355 0,25020047 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,04079355 0,24953504 ! cobalt ion transport GO:0006824 9 5 0,000 0,04079355 0,24887314 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,04079355 0,24821475 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,04079355 0,24755983 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,04079355 0,24690836 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,04079355 0,2462603 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,04079355 0,24561564 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,04079355 0,24497435 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,04079355 0,24433639 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,04079355 0,24370175 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,04079355 0,2430704 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04079355 0,24244231 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,04079355 0,24181746 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,04079355 0,24119582 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,04079355 0,24057737 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,04079355 0,23996209 ! malate metabolic process GO:0006108 7 5 0,000 0,04079355 0,23934994 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,04079355 0,2387409 ! behavioral response to pain GO:0048266 7 5 0,000 0,04079355 0,23813496 ! clathrin coat assembly GO:0048268 11 5 0,000 0,04079355 0,23753209 ! phototransduction, visible light GO:0007603 6 5 0,000 0,04079355 0,23693226 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04079355 0,23633545 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,04079355 0,23574165 ! mating behavior GO:0007617 6 5 0,000 0,04079355 0,23515082 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04079355 0,23456294 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,04079355 0,23397799 ! copulation GO:0007620 7 5 0,000 0,04079355 0,23339596 ! glial cell fate commitment GO:0021781 12 5 0,000 0,04079355 0,23281681 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,04079355 0,23224053 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,04079355 0,2316671 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,04079355 0,23109649 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,04079355 0,23052869 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,04079355 0,22996367 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,04079355 0,22940141 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,04079355 0,22884189 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04079355 0,2282851 ! lymph vessel development GO:0001945 7 5 0,000 0,04079355 0,22773101 ! endochondral ossification GO:0001958 12 5 0,000 0,04079355 0,2271796 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,04079355 0,22663086 ! parathyroid gland development GO:0060017 8 5 0,000 0,04079355 0,22608476 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,04079355 0,22554129 ! anagen GO:0042640 6 5 0,000 0,04079355 0,22500042 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,04079355 0,22446214 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,04079355 0,22392643 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,04079355 0,22339328 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,04079355 0,22286265 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,04079355 0,22233454 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,04079355 0,22180893 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,04079355 0,22128579 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,04079355 0,22076512 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,04079355 0,22024689 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,04079355 0,21973109 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,04079355 0,2192177 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,04079355 0,2187067 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,04079355 0,21819808 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,04079355 0,21769182 ! ovulation GO:0030728 6 5 0,000 0,04079355 0,21718791 ! response to pH GO:0009268 9 5 0,000 0,04079355 0,21668632 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,04079355 0,21618704 ! proline biosynthetic process GO:0006561 6 5 0,000 0,04079355 0,21569006 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04079355 0,21519536 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,04079355 0,21470292 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,04079355 0,21421273 ! polyol catabolic process GO:0046174 7 5 0,000 0,04079355 0,21372477 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04079355 0,21323904 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04079355 0,2127555 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04079355 0,21227415 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,04079355 0,21179498 ! nerve growth factor processing GO:0032455 7 5 0,000 0,04079355 0,21131796 ! urea metabolic process GO:0019627 6 5 0,000 0,04079355 0,21084309 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,04079355 0,21037035 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04079355 0,20989972 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,04079355 0,2094312 ! neutrophil activation GO:0042119 5 5 0,000 0,04079355 0,20896476 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,04079355 0,20850039 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,04079355 0,20803808 ! response to food GO:0032094 5 5 0,000 0,04079355 0,20757782 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,04079355 0,20711959 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04079355 0,20666338 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,04079355 0,20620918 ! forebrain neuron development GO:0021884 7 5 0,000 0,04079355 0,20575696 ! melanosome organization GO:0032438 7 5 0,000 0,04079355 0,20530673 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,04079355 0,20485846 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04079355 0,20441215 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,04079355 0,20396777 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04079355 0,20352533 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,04079355 0,2030848 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,04079355 0,20264617 ! nucleoside transport GO:0015858 6 5 0,000 0,04079355 0,20220943 ! nucleoside salvage GO:0043174 7 5 0,000 0,04079355 0,20177457 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,04079355 0,20134158 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,04079355 0,20091044 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,04079355 0,20048114 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,04079355 0,20005368 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04079355 0,19962803 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,04079355 0,19920419 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04079355 0,19878215 ! depyrimidination GO:0045008 8 5 0,000 0,04079355 0,19836189 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,04079355 0,19794341 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,04079355 0,19752669 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,04079355 0,19711171 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,04079355 0,19669848 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,04079355 0,19628698 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,04079355 0,19587719 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,04079355 0,19546912 ! monocyte differentiation GO:0030224 8 5 0,000 0,04079355 0,19506274 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,04079355 0,19465804 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04079355 0,19425502 ! centrosome duplication GO:0051298 5 5 0,000 0,04079355 0,19385367 ! response to UV-C GO:0010225 6 5 0,000 0,04079355 0,19345397 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,04079355 0,19305592 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,04079355 0,1926595 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,04079355 0,1922647 ! regulation of dendrite development GO:0050773 12 5 0,000 0,04079355 0,19187152 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,04079355 0,19147995 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,04079355 0,19108997 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,04079355 0,19070158 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,04079355 0,19031476 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,04079355 0,18992951 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,04079355 0,18954581 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,04079355 0,18916366 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,04079355 0,18878305 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,04079355 0,18840397 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,04079355 0,1880264 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04079355 0,18765035 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04079355 0,1872758 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,04079355 0,18690274 ! neural tube patterning GO:0021532 6 5 0,000 0,04079355 0,18653116 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,04079355 0,18616106 ! histone demethylation GO:0016577 9 5 0,000 0,04079355 0,18579243 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04079355 0,18542525 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04079355 0,18505952 GO:0032374|regulation of cholesterol transport, ! establishment of planar polarity GO:0001736 6 5 0,000 0,04079355 0,18469523 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,04079355 0,18433237 ! muscle cell proliferation GO:0033002 8 5 0,000 0,04079355 0,18397093 ! transcription termination GO:0006353 8 5 0,000 0,04079355 0,18361091 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,04079355 0,1832523 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,04079355 0,18289508 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,04079355 0,18253925 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,04079355 0,18218481 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04079355 0,18183174 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04079355 0,18148003 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,04079355 0,18112968 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,04079355 0,18078069 ! apical protein localization GO:0045176 6 5 0,000 0,04079355 0,18043303 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,04079355 0,18008671 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,04079355 0,17974172 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04079355 0,17939804 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04079355 0,17905568 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,04079355 0,17871462 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,04079355 0,17837486 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,04079355 0,17803639 ! glial cell migration GO:0008347 10 5 0,000 0,04079355 0,1776992 ! determination of adult lifespan GO:0008340 8 5 0,000 0,04079355 0,17736328 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,04079355 0,17702863 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04079355 0,17669525 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04079355 0,17636311 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,04079355 0,17603222 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,04079355 0,17570258 ! neural plate development GO:0001840 6 5 0,000 0,04079355 0,17537416 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,04079355 0,17504697 ! regulation of sensory perception GO:0051931 6 5 0,000 0,04079355 0,174721 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,04079355 0,17439624 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,04079355 0,17407268 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,04079355 0,17375033 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,04079355 0,17342916 ! sensory cilium assembly GO:0035058 6 5 0,000 0,04079355 0,17310918 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,04079355 0,17279038 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04079355 0,17247275 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,04079355 0,17215629 ! spindle assembly GO:0051225 5 5 0,000 0,04079355 0,17184098 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,04079355 0,17152683 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,04079355 0,17121382 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,04079355 0,17090196 ! organ regeneration GO:0031100 7 5 0,000 0,04079355 0,17059123 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,04079355 0,17028163 ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,04079355 0,16997314 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,04079355 0,16966578 GO:0055081|anion homeostasis, ! cell fate commitment GO:0045165 141 92 2,000 0,04111872 0,17070949 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,04223948 0,17504649 ! carbohydrate catabolic process GO:0016052 121 93 2,000 0,04223948 0,17473166 ! T cell differentiation GO:0030217 65 40 1,000 0,04340191 0,17921795 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,04340191 0,17889678 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,04538503 0,18673628 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,04740107 0,19468296 ! tRNA transcription GO:0009304 11 6 0,000 0,04875172 0,19987338 ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04875172 0,19951773 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04875172 0,19916335 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04875172 0,19881022 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04875172 0,19845835 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04875172 0,19810771 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04875172 0,19775832 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04875172 0,19741015 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04875172 0,19706321 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04875172 0,19671748 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04875172 0,19637297 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04875172 0,19602966 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04875172 0,19568755 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04875172 0,19534663 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04875172 0,1950069 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04875172 0,19466834 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04875172 0,19433096 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04875172 0,19399475 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04875172 0,1936597 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04875172 0,1933258 ! neuron adhesion GO:0007158 9 6 0,000 0,04875172 0,19299306 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04875172 0,19266145 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04875172 0,19233099 ! signal peptide processing GO:0006465 8 6 0,000 0,04875172 0,19200165 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04875172 0,19167345 ! mRNA stabilization GO:0048255 15 6 0,000 0,04875172 0,19134636 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04875172 0,19102039 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04875172 0,19069552 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04875172 0,19037176 ! opsonization GO:0008228 8 6 0,000 0,04875172 0,1900491 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04875172 0,18972752 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04875172 0,18940704 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04875172 0,18908763 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04875172 0,1887693 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04875172 0,18845204 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04875172 0,18813585 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04875172 0,18782071 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04875172 0,18750663 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04875172 0,1871936 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04875172 0,18688161 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04875172 0,18657066 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04875172 0,18626074 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04875172 0,18595185 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04875172 0,18564398 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04875172 0,18533713 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04875172 0,1850313 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04875172 0,18472647 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04875172 0,18442264 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04875172 0,18411981 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04875172 0,18381798 ! thymic T cell selection GO:0045061 12 6 0,000 0,04875172 0,18351713 ! protein lipoylation GO:0009249 10 6 0,000 0,04875172 0,18321727 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04875172 0,18291838 ! pigment granule organization GO:0048753 11 6 0,000 0,04875172 0,18262047 ! drug transport GO:0015893 6 6 0,000 0,04875172 0,18232352 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04875172 0,18202754 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04875172 0,18173252 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04875172 0,18143846 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04875172 0,18114534 ! histidine metabolic process GO:0006547 6 6 0,000 0,04875172 0,18085317 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04875172 0,18056194 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04875172 0,18027165 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,04875172 0,17998229 ! adenohypophysis development GO:0021984 10 6 0,000 0,04875172 0,17969386 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04875172 0,17940635 ! hyperosmotic response GO:0006972 8 6 0,000 0,04875172 0,17911975 ! microtubule nucleation GO:0007020 10 6 0,000 0,04875172 0,17883408 ! ER overload response GO:0006983 7 6 0,000 0,04875172 0,17854931 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04875172 0,17826545 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04875172 0,17798249 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04875172 0,17770042 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04875172 0,17741925 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04875172 0,17713897 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,04875172 0,17685957 ! response to dietary excess GO:0002021 7 6 0,000 0,04875172 0,17658105 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04875172 0,17630341 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04875172 0,17602663 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04875172 0,17575073 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04875172 0,17547569 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04875172 0,17520151 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04875172 0,17492818 ! neuron apoptosis GO:0051402 8 6 0,000 0,04875172 0,17465571 ! organic alcohol transport GO:0015850 9 6 0,000 0,04875172 0,17438408 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04875172 0,1741133 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04875172 0,17384336 ! carnitine transport GO:0015879 8 6 0,000 0,04875172 0,17357425 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04875172 0,17330598 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04875172 0,17303853 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04875172 0,1727719 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04875172 0,1725061 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04875172 0,17224112 ! parturition GO:0007567 12 6 0,000 0,04875172 0,17197694 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04875172 0,17171358 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04875172 0,17145102 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04875172 0,17118926 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04875172 0,1709283 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04875172 0,17066814 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04875172 0,17040876 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04875172 0,17015018 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04875172 0,16989237 ! macrophage differentiation GO:0030225 10 6 0,000 0,04875172 0,16963535 ! astrocyte development GO:0014002 14 6 0,000 0,04875172 0,1693791 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04875172 0,16912363 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04875172 0,16886893 ! interaction with symbiont GO:0051702 8 6 0,000 0,04875172 0,16861499 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04875172 0,16836181 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04875172 0,16810939 ! eating behavior GO:0042755 6 6 0,000 0,04875172 0,16785773 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04875172 0,16760683 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04875172 0,16735667 ! response to copper ion GO:0046688 9 6 0,000 0,04875172 0,16710725 ! DNA topological change GO:0006265 8 6 0,000 0,04875172 0,16685858 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04875172 0,16661065 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04875172 0,16636345 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04875172 0,16611699 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04875172 0,16587125 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04875172 0,16562624 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04875172 0,16538196 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04875172 0,16513839 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04875172 0,16489554 ! gas homeostasis GO:0033483 11 6 0,000 0,04875172 0,1646534 ! hair follicle maturation GO:0048820 7 6 0,000 0,04875172 0,16441197 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04875172 0,16417125 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04875172 0,16393124 ! Schwann cell development GO:0014044 14 6 0,000 0,04875172 0,16369192 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04875172 0,1634533 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04875172 0,16321538 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04875172 0,16297815 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04875172 0,16274161 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04875172 0,16250575 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04875172 0,16227057 ! histone ubiquitination GO:0016574 7 6 0,000 0,04875172 0,16203608 ! regulation of meiosis GO:0040020 10 6 0,000 0,04875172 0,16180226 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04875172 0,16156912 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04875172 0,16133664 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04875172 0,16110484 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04875172 0,1608737 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04875172 0,16064322 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04875172 0,1604134 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04875172 0,16018424 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04875172 0,15995573 ! receptor internalization GO:0031623 9 6 0,000 0,04875172 0,15972787 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04875172 0,15950066 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04875172 0,1592741 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 8 6 0,000 0,04875172 0,15904818 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04875172 0,1588229 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04875172 0,15859825 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04875172 0,15837425 ! axonal fasciculation GO:0007413 9 6 0,000 0,04875172 0,15815087 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04875172 0,15792812 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04875172 0,157706 ! midbrain development GO:0030901 6 6 0,000 0,04875172 0,1574845 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04875172 0,15726363 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04875172 0,15704337 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04875172 0,15682373 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04875172 0,1566047 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04875172 0,15638628 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04875172 0,15616848 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04875172 0,15595127 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04875172 0,15573468 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04875172 0,15551868 ! adult feeding behavior GO:0008343 6 6 0,000 0,04875172 0,15530328 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04875172 0,15508847 ! blastocyst growth GO:0001832 15 6 0,000 0,04875172 0,15487426 ! pigment granule transport GO:0051904 12 6 0,000 0,04875172 0,15466064 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04875172 0,15444761 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04875172 0,15423517 ! catecholamine transport GO:0051937 7 6 0,000 0,04875172 0,15402331 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04875172 0,15381203 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04875172 0,15360132 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,04875172 0,1533912 ! protein prenylation GO:0018342 10 6 0,000 0,04875172 0,15318165 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04875172 0,15297267 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04875172 0,15276426 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04875172 0,15255642 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04875172 0,15234914 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04875172 0,15214242 ! protein import GO:0017038 156 99 2,000 0,04928266 0,15359094 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,04928266 0,1533831 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,04944934 0,15369389 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,04944934 0,15348648 ! Ras protein signal transduction GO:0007265 162 100 2,000 0,050509 0,15656429 ! protein localization in organelle GO:0033365 161 100 2,000 0,050509 0,15635357 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,05152918 0,15929721 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,05363994 0,16559982 ! regulation of ossification GO:0030278 71 46 1,000 0,05578097 0,17197887 ! histone modification GO:0016570 68 46 1,000 0,05578097 0,17174864 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,05578097 0,17151903 ! response to UV GO:0009411 75 46 1,000 0,05578097 0,17129003 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05664432 0,17370925 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05664432 0,17347794 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05664432 0,17324726 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05664432 0,17301718 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05664432 0,17278771 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05664432 0,17255886 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05664432 0,1723306 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05664432 0,17210295 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05664432 0,17187591 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05664432 0,17164945 ! reproductive behavior GO:0019098 12 7 0,000 0,05664432 0,1714236 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05664432 0,17119834 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,05664432 0,17097367 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05664432 0,17074959 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,05664432 0,17052609 ! oligopeptide transport GO:0006857 11 7 0,000 0,05664432 0,17030318 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05664432 0,17008086 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05664432 0,16985911 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05664432 0,16963794 ! RNA methylation GO:0001510 11 7 0,000 0,05664432 0,16941734 ! pericardium development GO:0060039 8 7 0,000 0,05664432 0,16919732 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05664432 0,16897787 ! fibril organization GO:0043206 13 7 0,000 0,05664432 0,16875898 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05664432 0,16854067 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05664432 0,16832291 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,05664432 0,16810572 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05664432 0,16788909 ! lipoprotein transport GO:0042953 9 7 0,000 0,05664432 0,16767302 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05664432 0,1674575 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05664432 0,16724254 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05664432 0,16702812 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05664432 0,16681426 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05664432 0,16660094 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05664432 0,16638817 ! chemosensory behavior GO:0007635 9 7 0,000 0,05664432 0,16617594 ! microtubule bundle formation GO:0001578 8 7 0,000 0,05664432 0,16596425 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,05664432 0,1657531 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05664432 0,16554249 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05664432 0,16533241 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05664432 0,16512286 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05664432 0,16491384 ! reflex GO:0060004 12 7 0,000 0,05664432 0,16470536 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05664432 0,16449739 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05664432 0,16428996 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05664432 0,16408304 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05664432 0,16387665 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05664432 0,16367077 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05664432 0,16346542 ! spinal cord patterning GO:0021511 7 7 0,000 0,05664432 0,16326057 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05664432 0,16305624 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05664432 0,16285242 ! adrenal gland development GO:0030325 17 7 0,000 0,05664432 0,16264911 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05664432 0,1624463 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05664432 0,16224401 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05664432 0,16204221 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05664432 0,16184091 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05664432 0,16164012 ! endosome organization GO:0007032 10 7 0,000 0,05664432 0,16143982 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05664432 0,16124002 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05664432 0,16104071 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05664432 0,1608419 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05664432 0,16064357 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05664432 0,16044573 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05664432 0,16024838 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05664432 0,16005152 ! galactose metabolic process GO:0006012 10 7 0,000 0,05664432 0,15985514 ! vesicle fusion GO:0006906 15 7 0,000 0,05664432 0,15965924 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05664432 0,15946381 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05664432 0,15926887 ! organ growth GO:0035265 11 7 0,000 0,05664432 0,1590744 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05664432 0,15888041 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05664432 0,15868689 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05664432 0,15849384 ! retinol metabolic process GO:0042572 9 7 0,000 0,05664432 0,15830126 ! behavioral fear response GO:0001662 13 7 0,000 0,05664432 0,15810915 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05664432 0,1579175 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05664432 0,15772631 ! rRNA modification GO:0000154 12 7 0,000 0,05664432 0,15753559 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05664432 0,15734533 ! response to UV-B GO:0010224 11 7 0,000 0,05664432 0,15715553 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05664432 0,15696619 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05664432 0,1567773 ! intermediate filament organization GO:0045109 11 7 0,000 0,05664432 0,15658887 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05664432 0,15640088 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05664432 0,15621335 ! fibrinolysis GO:0042730 9 7 0,000 0,05664432 0,15602627 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05664432 0,15583964 ! B cell lineage commitment GO:0002326 17 7 0,000 0,05664432 0,15565345 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05664432 0,1554677 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05664432 0,1552824 ! response to tropane GO:0014073 13 7 0,000 0,05664432 0,15509754 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05664432 0,15491312 ! melanosome localization GO:0032400 10 7 0,000 0,05664432 0,15472914 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05664432 0,15454559 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05664432 0,15436248 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05664432 0,15417981 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05664432 0,15399756 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05664432 0,15381575 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05664432 0,15363436 ! mast cell activation GO:0045576 9 7 0,000 0,05664432 0,1534534 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05664432 0,15327287 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05664432 0,15309276 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05664432 0,15291307 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05664432 0,15273381 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05664432 0,15255496 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05664432 0,15237653 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05664432 0,15219852 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05664432 0,15202093 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05664432 0,15184375 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05664432 0,15166698 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05664432 0,15149062 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05664432 0,15131468 ! response to tumor cell GO:0002347 12 7 0,000 0,05664432 0,15113914 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05664432 0,150964 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05664432 0,15078928 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05664432 0,15061495 ! diuresis GO:0030146 12 7 0,000 0,05664432 0,15044103 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05664432 0,15026752 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05664432 0,1500944 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05664432 0,14992168 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05664432 0,14974935 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05664432 0,14957742 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05664432 0,14940589 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05664432 0,14923475 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05664432 0,149064 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05664432 0,14889364 ! lymph node development GO:0048535 9 7 0,000 0,05664432 0,14872367 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05664432 0,14855409 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05664432 0,14838489 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05664432 0,14821608 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05664432 0,14804765 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05664432 0,14787961 ! ATP catabolic process GO:0006200 10 7 0,000 0,05664432 0,14771195 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05664432 0,14754466 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05664432 0,14737776 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05664432 0,14721123 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05664432 0,14704507 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05664432 0,1468793 ! muscle adaptation GO:0043500 12 7 0,000 0,05664432 0,14671389 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05664432 0,14654886 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05664432 0,1463842 ! retina homeostasis GO:0001895 9 7 0,000 0,05664432 0,14621991 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05664432 0,14605598 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05664432 0,14589243 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05664432 0,14572923 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05664432 0,14556641 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05664432 0,14540395 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05664432 0,14524185 ! covalent chromatin modification GO:0016569 75 47 1,000 0,05795163 0,14842845 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,05795163 0,14826334 ! gastrulation GO:0007369 73 48 1,000 0,06015128 0,15371994 ! heart morphogenesis GO:0003007 65 48 1,000 0,06015128 0,15354933 ! regulation of DNA replication GO:0006275 75 48 1,000 0,06015128 0,1533791 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,06015128 0,15320925 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,06015128 0,15303977 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,06237931 0,15853306 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06447188 0,16367033 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06447188 0,16348988 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,06447188 0,16330982 ! axon extension GO:0048675 11 8 0,000 0,06447188 0,16313016 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06447188 0,1629509 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06447188 0,16277203 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06447188 0,16259355 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06447188 0,16241546 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06447188 0,16223777 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06447188 0,16206046 ! phosphate transport GO:0006817 10 8 0,000 0,06447188 0,16188354 ! N-glycan processing GO:0006491 12 8 0,000 0,06447188 0,161707 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06447188 0,16153085 ! UTP metabolic process GO:0046051 8 8 0,000 0,06447188 0,16135508 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06447188 0,16117969 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06447188 0,16100469 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06447188 0,16083006 ! succinate metabolic process GO:0006105 14 8 0,000 0,06447188 0,16065582 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,06447188 0,16048195 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06447188 0,16030845 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06447188 0,16013533 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,06447188 0,15996259 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06447188 0,15979021 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,06447188 0,15961821 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06447188 0,15944658 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06447188 0,15927532 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06447188 0,15910442 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06447188 0,15893389 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06447188 0,15876372 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06447188 0,15859392 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06447188 0,15842449 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06447188 0,15825541 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06447188 0,15808669 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06447188 0,15791834 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06447188 0,15775034 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06447188 0,1575827 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06447188 0,15741541 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06447188 0,15724848 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06447188 0,15708191 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06447188 0,15691568 ! melanin metabolic process GO:0006582 12 8 0,000 0,06447188 0,15674981 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06447188 0,15658429 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06447188 0,15641911 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06447188 0,15625429 ! macrophage activation GO:0042116 12 8 0,000 0,06447188 0,15608981 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06447188 0,15592568 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06447188 0,15576189 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06447188 0,15559845 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06447188 0,15543534 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06447188 0,15527259 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06447188 0,15511017 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06447188 0,15494809 ! ruffle organization GO:0031529 11 8 0,000 0,06447188 0,15478635 ! osteoblast development GO:0002076 13 8 0,000 0,06447188 0,15462494 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06447188 0,15446387 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06447188 0,15430314 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06447188 0,15414274 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06447188 0,15398268 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06447188 0,15382295 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06447188 0,15366354 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06447188 0,15350447 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06447188 0,15334573 ! brain morphogenesis GO:0048854 20 8 0,000 0,06447188 0,15318731 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06447188 0,15302923 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,06447188 0,15287146 ! cellular extravasation GO:0045123 11 8 0,000 0,06447188 0,15271403 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06447188 0,15255691 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06447188 0,15240012 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06447188 0,15224365 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,06447188 0,15208751 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06447188 0,15193168 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06447188 0,15177617 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06447188 0,15162098 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06447188 0,15146611 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,06447188 0,15131155 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06447188 0,15115731 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06447188 0,15100338 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06447188 0,15084977 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06447188 0,15069646 ! icosanoid secretion GO:0032309 12 8 0,000 0,06447188 0,15054347 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,06447188 0,15039079 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06447188 0,15023842 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06447188 0,15008636 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06447188 0,1499346 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06447188 0,14978315 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06447188 0,14963201 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06447188 0,14948117 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06447188 0,14933063 ! sterol catabolic process GO:0016127 9 8 0,000 0,06447188 0,1491804 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06447188 0,14903047 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06447188 0,14888084 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06447188 0,14873151 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06447188 0,14858248 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06447188 0,14843375 ! prophase GO:0051324 11 8 0,000 0,06447188 0,14828532 ! S phase GO:0051320 8 8 0,000 0,06447188 0,14813718 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06447188 0,14798934 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,06447188 0,14784179 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06447188 0,14769454 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06447188 0,14754758 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06447188 0,14740091 ! hormone catabolic process GO:0042447 13 8 0,000 0,06447188 0,14725454 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06447188 0,14710845 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06447188 0,14696266 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06447188 0,14681715 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06447188 0,14667193 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,06447188 0,146527 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06447188 0,14638235 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06447188 0,14623799 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06447188 0,14609391 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06447188 0,14595012 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06447188 0,14580661 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06447188 0,14566338 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06447188 0,14552043 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06447188 0,14537776 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06447188 0,14523538 ! lipid modification GO:0030258 73 50 1,000 0,0646351 0,1454606 ! positive regulation of secretion GO:0051047 71 51 1,000 0,06691804 0,15045113 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,06691804 0,1503042 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,06691804 0,15015756 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,06691804 0,15001121 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,06691804 0,14986514 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,06922754 0,15488653 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,07156301 0,15995619 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,07156301 0,15980089 ! single fertilization GO:0007338 59 53 1,000 0,07156301 0,1596459 ! cell projection assembly GO:0030031 76 53 1,000 0,07156301 0,1594912 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07223493 0,16083286 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07223493 0,16067731 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07223493 0,16052207 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07223493 0,16036712 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07223493 0,16021248 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07223493 0,16005813 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07223493 0,15990408 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07223493 0,15975033 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,07223493 0,15959687 ! GTP metabolic process GO:0046039 9 9 0,000 0,07223493 0,1594437 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07223493 0,15929083 ! social behavior GO:0035176 14 9 0,000 0,07223493 0,15913826 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07223493 0,15898597 ! artery development GO:0060840 19 9 0,000 0,07223493 0,15883398 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07223493 0,15868227 ! response to pain GO:0048265 16 9 0,000 0,07223493 0,15853086 ! protein complex disassembly GO:0043241 17 9 0,000 0,07223493 0,15837973 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07223493 0,15822889 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,07223493 0,15807834 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07223493 0,15792808 ! lung alveolus development GO:0048286 17 9 0,000 0,07223493 0,1577781 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07223493 0,15762841 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07223493 0,15747899 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07223493 0,15732987 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07223493 0,15718102 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07223493 0,15703246 ! protein targeting to ER GO:0045047 19 9 0,000 0,07223493 0,15688417 ! T cell selection GO:0045058 18 9 0,000 0,07223493 0,15673617 ! endoderm development GO:0007492 12 9 0,000 0,07223493 0,15658844 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07223493 0,156441 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07223493 0,15629383 ! arginine catabolic process GO:0006527 10 9 0,000 0,07223493 0,15614694 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07223493 0,15600032 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07223493 0,15585398 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07223493 0,15570791 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07223493 0,15556212 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,07223493 0,15541659 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07223493 0,15527135 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07223493 0,15512637 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07223493 0,15498166 ! mannose metabolic process GO:0006013 9 9 0,000 0,07223493 0,15483722 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07223493 0,15469305 ! receptor clustering GO:0043113 15 9 0,000 0,07223493 0,15454915 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07223493 0,15440552 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07223493 0,15426215 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07223493 0,15411905 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07223493 0,15397622 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07223493 0,15383365 ! motor axon guidance GO:0008045 14 9 0,000 0,07223493 0,15369134 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07223493 0,1535493 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,07223493 0,15340752 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07223493 0,153266 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07223493 0,15312474 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07223493 0,15298374 ! DNA ligation GO:0006266 14 9 0,000 0,07223493 0,152843 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07223493 0,15270252 ! response to amine stimulus GO:0014075 13 9 0,000 0,07223493 0,1525623 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07223493 0,15242233 ! erythrocyte development GO:0048821 11 9 0,000 0,07223493 0,15228262 ! renal water homeostasis GO:0003091 14 9 0,000 0,07223493 0,15214317 ! postreplication repair GO:0006301 11 9 0,000 0,07223493 0,15200397 ! mRNA cleavage GO:0006379 13 9 0,000 0,07223493 0,15186503 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07223493 0,15172634 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07223493 0,1515879 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07223493 0,15144972 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07223493 0,15131178 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07223493 0,1511741 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07223493 0,15103667 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,07223493 0,15089949 ! acid secretion GO:0046717 14 9 0,000 0,07223493 0,15076256 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07223493 0,15062587 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,07223493 0,15048944 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07223493 0,15035325 ! purine base metabolic process GO:0006144 18 9 0,000 0,07223493 0,15021731 ! oocyte differentiation GO:0009994 12 9 0,000 0,07223493 0,15008161 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,07223493 0,14994615 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07223493 0,14981095 ! spleen development GO:0048536 15 9 0,000 0,07223493 0,14967598 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07223493 0,14954126 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07223493 0,14940678 ! detection of calcium ion GO:0005513 13 9 0,000 0,07223493 0,14927254 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07223493 0,14913855 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07223493 0,14900479 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07223493 0,14887127 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07223493 0,14873799 ! prepulse inhibition GO:0060134 14 9 0,000 0,07223493 0,14860495 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07223493 0,14847215 ! insulin secretion GO:0030073 17 9 0,000 0,07223493 0,14833959 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07223493 0,14820726 ! response to nicotine GO:0035094 16 9 0,000 0,07223493 0,14807517 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07223493 0,14794331 ! nucleus localization GO:0051647 15 9 0,000 0,07223493 0,14781169 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07223493 0,1476803 ! amino acid transport GO:0006865 84 54 1,000 0,07392385 0,15099899 ! regulation of mitosis GO:0007088 84 54 1,000 0,07392385 0,15086501 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,07392385 0,15073126 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,07392385 0,15059776 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,07392385 0,15046448 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,07392385 0,15033145 ! mesoderm development GO:0007498 76 55 1,000 0,07630951 0,15504582 ! water-soluble vitamin metabolic process GO:0006767 71 55 1,000 0,07630951 0,15490898 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,0787194 0,15966017 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07993401 0,1619808 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07993401 0,16183821 ! neuron fate specification GO:0048665 11 10 0,000 0,07993401 0,16169588 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07993401 0,16155379 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07993401 0,16141195 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07993401 0,16127036 ! synapsis GO:0007129 13 10 0,000 0,07993401 0,16112902 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07993401 0,16098793 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07993401 0,16084708 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07993401 0,16070648 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,07993401 0,16056612 ! sulfate transport GO:0008272 12 10 0,000 0,07993401 0,16042601 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07993401 0,16028615 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07993401 0,16014653 ! androgen metabolic process GO:0008209 13 10 0,000 0,07993401 0,16000715 ! phospholipid efflux GO:0033700 16 10 0,000 0,07993401 0,15986801 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07993401 0,15972912 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07993401 0,15959046 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07993401 0,15945205 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07993401 0,15931388 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,07993401 0,15917594 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07993401 0,15903825 ! pathogenesis GO:0009405 13 10 0,000 0,07993401 0,15890079 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07993401 0,15876357 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07993401 0,15862658 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07993401 0,15848984 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,07993401 0,15835333 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07993401 0,15821705 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07993401 0,15808101 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07993401 0,1579452 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07993401 0,15780962 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07993401 0,15767428 ! response to X-ray GO:0010165 16 10 0,000 0,07993401 0,15753917 ! B cell proliferation GO:0042100 14 10 0,000 0,07993401 0,15740429 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07993401 0,15726964 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07993401 0,15713522 ! forebrain cell migration GO:0021885 17 10 0,000 0,07993401 0,15700103 ! lipid digestion GO:0044241 15 10 0,000 0,07993401 0,15686707 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07993401 0,15673334 ! UV protection GO:0009650 14 10 0,000 0,07993401 0,15659984 ! entry into host cell GO:0030260 20 10 0,000 0,07993401 0,15646656 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,07993401 0,15633351 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07993401 0,15620069 ! negative regulation of ossification GO:0030279 19 10 0,000 0,07993401 0,15606809 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07993401 0,15593572 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,07993401 0,15580357 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07993401 0,15567164 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,07993401 0,15553994 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07993401 0,15540846 ! response to dsRNA GO:0043331 18 10 0,000 0,07993401 0,15527721 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07993401 0,15514617 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07993401 0,15501536 ! embryonic axis specification GO:0000578 12 10 0,000 0,07993401 0,15488476 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07993401 0,15475439 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07993401 0,15462423 ! fucose catabolic process GO:0019317 16 10 0,000 0,07993401 0,1544943 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07993401 0,15436458 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07993401 0,15423508 ! protein sumoylation GO:0016925 12 10 0,000 0,07993401 0,15410579 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07993401 0,15397673 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07993401 0,15384788 ! zymogen activation GO:0031638 14 10 0,000 0,07993401 0,15371924 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07993401 0,15359082 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07993401 0,15346261 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07993401 0,15333462 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07993401 0,15320684 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07993401 0,15307928 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07993401 0,15295192 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07993401 0,15282478 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07993401 0,15269785 ! detection of bacterium GO:0016045 10 10 0,000 0,07993401 0,15257113 ! embryonic gut development GO:0048566 11 10 0,000 0,07993401 0,15244462 ! activation of innate immune response GO:0002218 10 10 0,000 0,07993401 0,15231832 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07993401 0,15219223 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07993401 0,15206635 ! developmental induction GO:0031128 13 10 0,000 0,07993401 0,15194067 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07993401 0,1518152 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07993401 0,15168994 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07993401 0,15156489 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07993401 0,15144004 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,08115298 0,15362292 GO:0048609|reproductive process in a multicellular organism, ! viral reproductive process GO:0022415 87 58 1,000 0,08360968 0,15814332 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,08360968 0,15801337 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,08360968 0,15788364 ! activation of MAPK activity GO:0000187 84 59 1,000 0,08608897 0,16243202 ! rRNA transcription GO:0009303 17 11 0,000 0,08756963 0,16509028 ! respiratory burst GO:0045730 14 11 0,000 0,08756963 0,16495507 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,08756963 0,16482008 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,08756963 0,16468531 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,08756963 0,16455077 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,08756963 0,16441644 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,08756963 0,16428233 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,08756963 0,16414844 ! RNA polyadenylation GO:0043631 19 11 0,000 0,08756963 0,16401477 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,08756963 0,16388132 ! mating GO:0007618 14 11 0,000 0,08756963 0,16374808 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,08756963 0,16361506 ! T cell proliferation GO:0042098 20 11 0,000 0,08756963 0,16348226 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,08756963 0,16334967 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,08756963 0,16321729 ! regulated secretory pathway GO:0045055 14 11 0,000 0,08756963 0,16308513 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,08756963 0,16295319 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,08756963 0,16282146 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,08756963 0,16268994 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,08756963 0,16255863 ! syncytium formation GO:0006949 15 11 0,000 0,08756963 0,16242753 ! plasma membrane organization GO:0007009 18 11 0,000 0,08756963 0,16229665 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,08756963 0,16216597 ! mitotic spindle organization GO:0007052 15 11 0,000 0,08756963 0,16203551 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,08756963 0,16190526 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,08756963 0,16177521 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,08756963 0,16164538 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,08756963 0,16151575 ! adult heart development GO:0007512 11 11 0,000 0,08756963 0,16138633 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,08756963 0,16125712 ! temperature homeostasis GO:0001659 16 11 0,000 0,08756963 0,16112811 ! L-glutamate transport GO:0015813 16 11 0,000 0,08756963 0,16099931 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,08756963 0,16087072 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,08756963 0,16074233 ! stem cell development GO:0048864 29 11 0,000 0,08756963 0,16061415 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,08756963 0,16048617 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,08756963 0,16035839 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,08756963 0,16023082 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,08756963 0,16010345 ! vasoconstriction GO:0042310 15 11 0,000 0,08756963 0,15997628 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,08756963 0,15984932 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,08756963 0,15972255 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,08756963 0,15959599 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,08756963 0,15946963 ! ribosome assembly GO:0042255 13 11 0,000 0,08756963 0,15934347 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,08756963 0,1592175 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,08756963 0,15909174 ! chromatin silencing GO:0006342 19 11 0,000 0,08756963 0,15896617 ! nucleosome positioning GO:0016584 13 11 0,000 0,08756963 0,1588408 ! T cell homeostasis GO:0043029 20 11 0,000 0,08756963 0,15871563 ! regulation of isotype switching GO:0045191 19 11 0,000 0,08756963 0,15859066 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,08756963 0,15846589 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,08756963 0,15834131 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,08756963 0,15821692 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,08756963 0,15809273 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,08756963 0,15796874 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,08756963 0,15784494 ! male genitalia development GO:0030539 13 11 0,000 0,08756963 0,15772133 ! cholesterol efflux GO:0033344 19 11 0,000 0,08756963 0,15759792 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,08756963 0,1574747 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,08756963 0,15735167 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,08756963 0,15722884 ! germ cell migration GO:0008354 18 11 0,000 0,08756963 0,15710619 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,08756963 0,15698374 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,08756963 0,15686148 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,08756963 0,15673941 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,08756963 0,15661753 ! lysogeny GO:0030069 18 11 0,000 0,08756963 0,15649584 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,08756963 0,15637433 ! acrosome reaction GO:0007340 13 11 0,000 0,08756963 0,15625302 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,08756963 0,15613189 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,08859031 0,15782936 ! fertilization GO:0009566 68 60 1,000 0,08859031 0,1577072 ! meiosis GO:0007126 96 61 1,000 0,09111316 0,1620729 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 1,000 0,093657 0,16646917 ! meiotic cell cycle GO:0051321 97 62 1,000 0,093657 0,16634062 ! lactation GO:0007595 20 12 0,000 0,09514231 0,16884824 ! reproductive cellular process GO:0048610 14 12 0,000 0,09514231 0,16871806 ! tRNA modification GO:0006400 14 12 0,000 0,09514231 0,16858807 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,09514231 0,16845829 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,09514231 0,16832871 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,09514231 0,16819932 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,09514231 0,16807014 ! non-recombinational repair GO:0000726 19 12 0,000 0,09514231 0,16794115 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,09514231 0,16781236 ! peroxisomal transport GO:0043574 21 12 0,000 0,09514231 0,16768377 ! cartilage condensation GO:0001502 18 12 0,000 0,09514231 0,16755537 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,09514231 0,16742718 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,09514231 0,16729917 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,09514231 0,16717137 ! heart looping GO:0001947 15 12 0,000 0,09514231 0,16704375 ! palate development GO:0060021 15 12 0,000 0,09514231 0,16691634 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,09514231 0,16678911 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,09514231 0,16666209 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,09514231 0,16653525 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,09514231 0,16640861 ! arginine metabolic process GO:0006525 13 12 0,000 0,09514231 0,16628216 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,09514231 0,1661559 ! methionine metabolic process GO:0006555 13 12 0,000 0,09514231 0,16602983 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,09514231 0,16590396 ! Golgi organization GO:0007030 18 12 0,000 0,09514231 0,16577827 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,09514231 0,16565278 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,09514231 0,16552747 ! monoamine transport GO:0015844 13 12 0,000 0,09514231 0,16540236 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,09514231 0,16527743 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,09514231 0,16515269 ! L-amino acid transport GO:0015807 20 12 0,000 0,09514231 0,16502814 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,09514231 0,16490378 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,09514231 0,16477961 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,09514231 0,16465562 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,09514231 0,16453182 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,09514231 0,1644082 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,09514231 0,16428477 ! cerebellum development GO:0021549 13 12 0,000 0,09514231 0,16416153 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,09514231 0,16403847 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,09514231 0,16391559 ! histone methylation GO:0016571 15 12 0,000 0,09514231 0,1637929 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,09514231 0,1636704 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,09514231 0,16354807 ! response to gamma radiation GO:0010332 20 12 0,000 0,09514231 0,16342593 ! regulation of epidermis development GO:0045682 17 12 0,000 0,09514231 0,16330397 ! intestinal absorption GO:0050892 19 12 0,000 0,09514231 0,16318219 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,09514231 0,1630606 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,09514231 0,16293918 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,09514231 0,16281795 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,09514231 0,16269689 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,09514231 0,16257602 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,09514231 0,16245532 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,09514231 0,16233481 ! microspike assembly GO:0030035 23 12 0,000 0,09514231 0,16221447 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,09514231 0,16209431 ! response to cold GO:0009409 14 12 0,000 0,09514231 0,16197433 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,09622133 0,16369013 ! viral reproduction GO:0016032 92 63 1,000 0,09622133 0,16356914 ! regulation of lipase activity GO:0060191 109 63 1,000 0,09622133 0,16344834 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,09880562 0,16771433 ! negative regulation of cell size GO:0045792 108 64 1,000 0,09880562 0,16759065 ! reproductive structure development GO:0048608 90 65 1,000 0,10140938 0,1718803 ! defense response to bacterium GO:0042742 73 65 1,000 0,10140938 0,17175373 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,10140938 0,17162735 ! protein oligomerization GO:0051259 100 65 1,000 0,10140938 0,17150115 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,10265258 0,17347607 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,10265258 0,1733487 ! cGMP metabolic process GO:0046068 16 13 0,000 0,10265258 0,17322152 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,10265258 0,17309453 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,10265258 0,17296772 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,10265258 0,17284109 ! lipid localization GO:0010876 24 13 0,000 0,10265258 0,17271465 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,10265258 0,1725884 ! organelle fusion GO:0048284 28 13 0,000 0,10265258 0,17246233 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,10265258 0,17233645 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,10265258 0,17221075 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,10265258 0,17208523 ! response to hexose stimulus GO:0009746 19 13 0,000 0,10265258 0,17195989 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,10265258 0,17183474 ! glutamate metabolic process GO:0006536 18 13 0,000 0,10265258 0,17170977 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,10265258 0,17158498 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,10265258 0,17146037 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,10265258 0,17133595 ! NAD metabolic process GO:0019674 21 13 0,000 0,10265258 0,1712117 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,10265258 0,17108763 ! bone mineralization GO:0030282 15 13 0,000 0,10265258 0,17096375 ! regulation of exocytosis GO:0017157 17 13 0,000 0,10265258 0,17084004 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,10265258 0,17071651 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,10265258 0,17059316 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,10265258 0,17046999 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,10265258 0,17034699 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,10265258 0,17022418 ! genitalia development GO:0048806 15 13 0,000 0,10265258 0,17010154 ! regulation of cellular pH GO:0030641 20 13 0,000 0,10265258 0,16997907 ! cellular pigmentation GO:0033059 24 13 0,000 0,10265258 0,16985679 ! tissue regeneration GO:0042246 21 13 0,000 0,10265258 0,16973467 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,10265258 0,16961274 ! cofactor transport GO:0051181 19 13 0,000 0,10265258 0,16949098 ! NADP metabolic process GO:0006739 18 13 0,000 0,10265258 0,16936939 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,10265258 0,16924798 ! gas transport GO:0015669 18 13 0,000 0,10265258 0,16912674 ! regulation of RNA stability GO:0043487 28 13 0,000 0,10265258 0,16900568 ! heme biosynthetic process GO:0006783 20 13 0,000 0,10265258 0,16888479 ! regulation of axon extension GO:0030516 23 13 0,000 0,10265258 0,16876407 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,10265258 0,16864352 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,10265258 0,16852315 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,10265258 0,16840295 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,10265258 0,16828292 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,10265258 0,16816306 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,10265258 0,16804337 ! axon guidance GO:0007411 99 66 1,000 0,10403211 0,17018054 ! regulation of immune effector process GO:0002697 101 66 1,000 0,10403211 0,17005959 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,10667332 0,17425329 ! acute inflammatory response GO:0002526 92 68 1,000 0,10933254 0,17847043 ! rhythmic process GO:0048511 105 68 1,000 0,10933254 0,17834385 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,11010094 0,17946999 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,11010094 0,17934289 ! superoxide anion generation GO:0042554 18 14 0,000 0,11010094 0,17921596 ! regulation of S phase GO:0033261 18 14 0,000 0,11010094 0,17908922 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,11010094 0,17896266 ! myotube differentiation GO:0014902 21 14 0,000 0,11010094 0,17883627 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,11010094 0,17871006 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,11010094 0,17858403 ! inositol metabolic process GO:0006020 20 14 0,000 0,11010094 0,17845818 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,11010094 0,17833251 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,11010094 0,17820701 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,11010094 0,17808169 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,11010094 0,17795654 ! gene silencing by RNA GO:0031047 20 14 0,000 0,11010094 0,17783157 ! response to cAMP GO:0051591 19 14 0,000 0,11010094 0,17770678 ! startle response GO:0001964 21 14 0,000 0,11010094 0,17758216 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,11010094 0,17745771 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,11010094 0,17733344 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,11010094 0,17720935 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,11010094 0,17708542 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,11010094 0,17696168 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,11010094 0,1768381 ! glycine metabolic process GO:0006544 22 14 0,000 0,11010094 0,17671469 ! pituitary gland development GO:0021983 23 14 0,000 0,11010094 0,17659146 ! cellular response to starvation GO:0009267 21 14 0,000 0,11010094 0,1764684 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,11010094 0,17634551 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,11010094 0,1762228 ! regulation of heart rate GO:0002027 23 14 0,000 0,11010094 0,17610025 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,11010094 0,17597787 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,11010094 0,17585566 ! embryo implantation GO:0007566 27 14 0,000 0,11010094 0,17573363 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,11010094 0,17561176 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,11010094 0,17549006 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,11010094 0,17536853 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,11010094 0,17524717 ! axon cargo transport GO:0008088 27 14 0,000 0,11010094 0,17512597 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,11010094 0,17500495 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,11010094 0,17488409 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,11010094 0,17476339 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,11010094 0,17464287 ! mRNA splice site selection GO:0006376 26 14 0,000 0,11010094 0,17452251 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,11010094 0,17440231 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,11010094 0,17428228 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,11010094 0,17416242 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,11010094 0,17404272 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,11010094 0,17392319 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,11010094 0,17380381 ! muscle maintenance GO:0046716 19 14 0,000 0,11010094 0,17368461 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,11010094 0,17356556 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,11010094 0,17344668 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,11010094 0,17332797 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,11010094 0,17320941 ! cell killing GO:0001906 20 14 0,000 0,11010094 0,17309102 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,11010094 0,17297279 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,11010094 0,17285472 ! cilium assembly GO:0042384 20 14 0,000 0,11010094 0,17273681 ! amine transport GO:0015837 101 70 1,000 0,11470308 0,17983441 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,11741348 0,18395845 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,11741348 0,18383322 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,1174879 0,1838246 ! positive regulation of cell size GO:0045793 20 15 0,000 0,1174879 0,18369963 ! metencephalon development GO:0022037 19 15 0,000 0,1174879 0,18357484 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,1174879 0,18345021 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,1174879 0,18332575 ! skin development GO:0043588 25 15 0,000 0,1174879 0,18320146 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,1174879 0,18307734 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,1174879 0,18295339 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,1174879 0,18282961 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,1174879 0,18270599 ! bile acid metabolic process GO:0008206 22 15 0,000 0,1174879 0,18258254 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,1174879 0,18245926 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,1174879 0,18233614 ! adult walking behavior GO:0007628 25 15 0,000 0,1174879 0,18221319 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,1174879 0,1820904 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,1174879 0,18196778 ! myoblast differentiation GO:0045445 27 15 0,000 0,1174879 0,18184533 ! centrosome cycle GO:0007098 16 15 0,000 0,1174879 0,18172304 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,1174879 0,18160091 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,1174879 0,18147895 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,1174879 0,18135715 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,1174879 0,18123552 ! cerebral cortex development GO:0021987 29 15 0,000 0,1174879 0,18111405 ! response to osmotic stress GO:0006970 22 15 0,000 0,1174879 0,18099274 ! vesicle coating GO:0006901 25 15 0,000 0,1174879 0,18087159 ! DNA integration GO:0015074 22 15 0,000 0,1174879 0,18075061 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,1174879 0,18062979 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,1174879 0,18050912 ! regulation of vasodilation GO:0042312 24 15 0,000 0,1174879 0,18038862 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,1174879 0,18026828 ! neuron recognition GO:0008038 22 15 0,000 0,1174879 0,18014811 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,1174879 0,18002809 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,1174879 0,17990823 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,1174879 0,17978853 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,1174879 0,17966899 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,1174879 0,17954961 ! biomineral formation GO:0031214 18 15 0,000 0,1174879 0,17943038 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,1174879 0,17931132 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,1174879 0,17919241 ! dopamine metabolic process GO:0042417 30 15 0,000 0,1174879 0,17907366 ! organic cation transport GO:0015695 19 15 0,000 0,1174879 0,17895507 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,1174879 0,17883664 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,1174879 0,17871836 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,1174879 0,17860024 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,1174879 0,17848227 ! peptide hormone processing GO:0016486 19 15 0,000 0,1174879 0,17836446 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,1174879 0,17824681 ! response to hypoxia GO:0001666 132 72 1,000 0,12014002 0,18215032 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,12288225 0,18618522 ! protein secretion GO:0009306 27 16 0,000 0,12481395 0,18898755 ! endothelial cell migration GO:0043542 22 16 0,000 0,12481395 0,18886322 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,12481395 0,18873905 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,12481395 0,18861504 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,12481395 0,1884912 ! glial cell development GO:0021782 24 16 0,000 0,12481395 0,18836751 ! patterning of blood vessels GO:0001569 24 16 0,000 0,12481395 0,18824399 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,12481395 0,18812064 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,12481395 0,18799744 ! protein polyubiquitination GO:0000209 26 16 0,000 0,12481395 0,18787441 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,12481395 0,18775153 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,12481395 0,18762882 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,12481395 0,18750627 ! fructose metabolic process GO:0006000 20 16 0,000 0,12481395 0,18738387 ! regulation of protein binding GO:0043393 27 16 0,000 0,12481395 0,18726164 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,12481395 0,18713956 ! protein export from nucleus GO:0006611 24 16 0,000 0,12481395 0,18701765 ! negative regulation of immune response GO:0050777 28 16 0,000 0,12481395 0,18689589 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,12481395 0,1867743 ! DNA replication initiation GO:0006270 25 16 0,000 0,12481395 0,18665286 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,12481395 0,18653157 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,12481395 0,18641045 ! diencephalon development GO:0021536 25 16 0,000 0,12481395 0,18628948 ! oogenesis GO:0048477 23 16 0,000 0,12481395 0,18616867 ! G1 phase GO:0051318 27 16 0,000 0,12481395 0,18604802 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,12481395 0,18592752 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,12481395 0,18580718 ! steroid catabolic process GO:0006706 22 16 0,000 0,12481395 0,18568699 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,12481395 0,18556696 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,12481395 0,18544709 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,12481395 0,18532737 ! sperm-egg recognition GO:0035036 16 16 0,000 0,12481395 0,1852078 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,12481395 0,18508839 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,12481395 0,18496913 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,12481395 0,18485003 ! negative regulation of translation GO:0017148 22 16 0,000 0,12481395 0,18473108 ! response to oxygen levels GO:0070482 137 74 1,000 0,12563973 0,18583368 ! blood coagulation GO:0007596 116 75 1,000 0,12841202 0,18981211 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 1,000 0,12841202 0,1896902 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,13207961 0,19498274 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,13207961 0,19485767 ! negative regulation of defense response GO:0031348 19 17 0,000 0,13207961 0,19473276 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,13207961 0,19460801 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,13207961 0,19448342 ! glycerol metabolic process GO:0006071 20 17 0,000 0,13207961 0,19435899 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,13207961 0,19423472 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,13207961 0,19411061 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,13207961 0,19398666 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,13207961 0,19386286 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,13207961 0,19373922 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,13207961 0,19361575 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,13207961 0,19349242 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,13207961 0,19336926 ! memory GO:0007613 25 17 0,000 0,13207961 0,19324625 ! keratinization GO:0031424 17 17 0,000 0,13207961 0,1931234 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,13207961 0,1930007 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,13207961 0,19287816 ! retinoid metabolic process GO:0001523 22 17 0,000 0,13207961 0,19275578 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,13207961 0,19263355 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,13207961 0,19251147 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,13207961 0,19238955 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,13207961 0,19226779 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,13207961 0,19214618 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,13207961 0,19202472 ! membrane budding GO:0006900 29 17 0,000 0,13207961 0,19190341 ! heme metabolic process GO:0042168 27 17 0,000 0,13207961 0,19178226 ! neuromuscular junction development GO:0007528 23 17 0,000 0,13207961 0,19166126 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,13207961 0,19154042 ! body fluid secretion GO:0007589 27 17 0,000 0,13207961 0,19141973 ! stem cell differentiation GO:0048863 36 17 0,000 0,13207961 0,19129918 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,13207961 0,19117879 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,13207961 0,19105856 ! sensory perception of pain GO:0019233 23 17 0,000 0,13207961 0,19093847 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,13207961 0,19081853 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,13207961 0,19069875 ! synaptogenesis GO:0007416 24 17 0,000 0,13207961 0,19057911 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,13207961 0,19045963 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,13207961 0,19034029 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,13207961 0,1902211 ! cell-cell junction organization GO:0045216 25 17 0,000 0,13207961 0,19010207 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,13207961 0,18998318 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,13207961 0,18986444 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,13207961 0,18974585 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,13207961 0,18962741 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,13207961 0,18950911 ! protein ubiquitination GO:0016567 125 77 1,000 0,13399932 0,19214366 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,13399932 0,19202394 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,13928536 0,19947468 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,13928536 0,19935055 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,13928536 0,19922658 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,13928536 0,19910276 ! cAMP metabolic process GO:0046058 33 18 0,000 0,13928536 0,19897909 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,13928536 0,19885558 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,13928536 0,19873222 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,13928536 0,19860901 ! axis specification GO:0009798 26 18 0,000 0,13928536 0,19848596 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,13928536 0,19836306 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,13928536 0,19824031 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,13928536 0,19811771 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,13928536 0,19799526 ! glutamine metabolic process GO:0006541 23 18 0,000 0,13928536 0,19787297 ! response to retinoic acid GO:0032526 25 18 0,000 0,13928536 0,19775082 ! pigmentation during development GO:0048066 31 18 0,000 0,13928536 0,19762883 ! central nervous system neuron development GO:0021954 30 18 0,000 0,13928536 0,19750699 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,13928536 0,1973853 ! fucose metabolic process GO:0006004 26 18 0,000 0,13928536 0,19726375 ! response to fungus GO:0009620 19 18 0,000 0,13928536 0,19714236 ! peptide cross-linking GO:0018149 31 18 0,000 0,13928536 0,19702112 ! heart process GO:0003015 27 18 0,000 0,13928536 0,19690002 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,13928536 0,19677907 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 35 18 0,000 0,13928536 0,19665828 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,13928536 0,19653763 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,13928536 0,19641713 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,13928536 0,19629677 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,13928536 0,19617657 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,13928536 0,19605651 ! vitamin transport GO:0051180 24 18 0,000 0,13928536 0,1959366 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,13928536 0,19581683 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,13928536 0,19569721 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,13928536 0,19557774 ! cell-cell recognition GO:0009988 20 18 0,000 0,13928536 0,19545841 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,13928536 0,19533923 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,13928536 0,19522019 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,13928536 0,1951013 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,13928536 0,19498255 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,13928536 0,19486395 ! T cell activation GO:0042110 134 79 1,000 0,13964077 0,19524242 ! forebrain development GO:0030900 131 80 1,000 0,14248078 0,19909222 ! hemostasis GO:0007599 125 81 1,000 0,14533311 0,20295455 ! vitamin metabolic process GO:0006766 103 81 1,000 0,14533311 0,2028314 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,1464317 0,2042407 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,1464317 0,20411691 ! positive regulation of ossification GO:0045778 30 19 0,000 0,1464317 0,20399328 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,1464317 0,2038698 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,1464317 0,20374647 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,1464317 0,20362328 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,1464317 0,20350025 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,1464317 0,20337736 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,1464317 0,20325462 ! regeneration GO:0031099 32 19 0,000 0,1464317 0,20313203 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,1464317 0,20300959 ! response to alkaloid GO:0043279 32 19 0,000 0,1464317 0,20288729 ! sensory perception of taste GO:0050909 23 19 0,000 0,1464317 0,20276515 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,1464317 0,20264315 ! smooth muscle contraction GO:0006939 36 19 0,000 0,1464317 0,20252129 ! peroxisome organization GO:0007031 29 19 0,000 0,1464317 0,20239958 ! digestive system process GO:0022600 30 19 0,000 0,1464317 0,20227802 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,1464317 0,20215661 ! response to vitamin A GO:0033189 26 19 0,000 0,1464317 0,20203534 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,1464317 0,20191421 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,1464317 0,20179323 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,1464317 0,2016724 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,1464317 0,20155171 ! response to starvation GO:0042594 30 19 0,000 0,1464317 0,20143117 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,1464317 0,20131076 ! plasma membrane fusion GO:0045026 23 19 0,000 0,1464317 0,20119051 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,1464317 0,20107039 ! cytolysis GO:0019835 20 19 0,000 0,1464317 0,20095042 ! renal system process GO:0003014 35 19 0,000 0,1464317 0,2008306 ! vasodilation GO:0042311 33 19 0,000 0,1464317 0,20071091 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,1464317 0,20059137 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,1464317 0,20047197 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,1464317 0,20035271 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,1464317 0,2002336 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,1464317 0,20011462 ! sarcomere organization GO:0045214 23 19 0,000 0,1464317 0,19999579 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,1464317 0,1998771 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,1464317 0,19975855 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,1464317 0,19964014 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,1464317 0,19952186 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,1464317 0,19940373 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,1464317 0,19928574 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,1464317 0,19916789 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,1464317 0,19905018 ! protein stabilization GO:0050821 26 19 0,000 0,1464317 0,19893261 ! ossification GO:0001503 134 82 1,000 0,14819735 0,20121246 GO:0060348|bone development, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,15107313 0,20499599 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,15107313 0,20487512 ! iron ion transport GO:0006826 37 20 0,000 0,15351911 0,2080695 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,15351911 0,20794696 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,15351911 0,20782457 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,15351911 0,20770232 ! response to vitamin GO:0033273 29 20 0,000 0,15351911 0,20758022 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,15351911 0,20745825 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,15351911 0,20733643 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,15351911 0,20721476 ! spinal cord development GO:0021510 31 20 0,000 0,15351911 0,20709322 ! response to ethanol GO:0045471 37 20 0,000 0,15351911 0,20697183 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,15351911 0,20685058 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,15351911 0,20672948 ! chromosome condensation GO:0030261 31 20 0,000 0,15351911 0,20660851 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,15351911 0,20648769 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,15351911 0,20636701 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,15351911 0,20624646 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,15351911 0,20612606 ! DNA modification GO:0006304 28 20 0,000 0,15351911 0,2060058 ! collagen fibril organization GO:0030199 45 20 0,000 0,15351911 0,20588568 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,15351911 0,2057657 ! collagen catabolic process GO:0030574 25 20 0,000 0,15351911 0,20564586 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,15351911 0,20552616 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,15351911 0,2054066 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,15351911 0,20528718 ! alditol metabolic process GO:0019400 24 20 0,000 0,15351911 0,20516789 ! actin filament-based movement GO:0030048 34 20 0,000 0,15351911 0,20504875 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,15685774 0,20938642 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,16054807 0,21418826 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,16054807 0,21406409 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,16054807 0,21394007 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,16054807 0,21381619 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,16054807 0,21369245 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,16054807 0,21356886 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,16054807 0,21344541 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,16054807 0,2133221 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,16054807 0,21319894 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,16054807 0,21307591 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,16054807 0,21295303 ! vesicle docking GO:0048278 27 21 0,000 0,16054807 0,21283029 ! phototransduction GO:0007602 25 21 0,000 0,16054807 0,21270769 ! dendrite development GO:0016358 35 21 0,000 0,16054807 0,21258524 ! visual behavior GO:0007632 39 21 0,000 0,16054807 0,21246292 ! ovarian follicle development GO:0001541 30 21 0,000 0,16054807 0,21234075 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,16054807 0,21221871 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,16054807 0,21209682 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,16054807 0,21197506 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,16054807 0,21185345 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,16054807 0,21173197 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,16054807 0,21161064 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,16054807 0,21148944 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,16054807 0,21136838 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,16054807 0,21124746 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,16054807 0,21112668 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,16054807 0,21100603 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,16054807 0,21088553 ! fatty acid transport GO:0015908 30 21 0,000 0,16054807 0,21076516 ! immunoglobulin production GO:0002377 33 21 0,000 0,16054807 0,21064493 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,16054807 0,21052483 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,16054807 0,21040488 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,16054807 0,21028506 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,16054807 0,21016537 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,16054807 0,21004582 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,16054807 0,20992641 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,16054807 0,20980714 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,16054807 0,20968799 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,16054807 0,20956899 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,16054807 0,20945012 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,16054807 0,20933138 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,16054807 0,20921278 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,16268394 0,21187602 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,16268394 0,21175612 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,16751906 0,21792638 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,16751906 0,21780319 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,16751906 0,21768014 ! viral genome replication GO:0019079 29 22 0,000 0,16751906 0,21755722 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,16751906 0,21743445 ! leukocyte adhesion GO:0007159 38 22 0,000 0,16751906 0,21731181 ! molting cycle process GO:0022404 40 22 0,000 0,16751906 0,21718932 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,16751906 0,21706695 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,16751906 0,21694473 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,16751906 0,21682265 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,16751906 0,2167007 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,16751906 0,21657889 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,16751906 0,21645722 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,16751906 0,21633568 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,16751906 0,21621428 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,16751906 0,21609301 ! lysosome organization GO:0007040 37 22 0,000 0,16751906 0,21597189 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,16751906 0,21585089 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,16751906 0,21573004 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,16751906 0,21560931 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,16751906 0,21548873 ! membrane depolarization GO:0051899 35 22 0,000 0,16751906 0,21536828 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,16751906 0,21524796 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,16751906 0,21512777 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,16751906 0,21500773 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,16751906 0,21488781 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,16751906 0,21476803 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,16854879 0,21596781 ! leukocyte differentiation GO:0002521 143 90 1,000 0,17149483 0,21962033 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,17149483 0,21949811 ! neuron fate commitment GO:0048663 32 23 0,000 0,17443256 0,22313398 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,17443256 0,22300995 ! myelination GO:0042552 35 23 0,000 0,17443256 0,22288605 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,17443256 0,2227623 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,17443256 0,22263868 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,17443256 0,2225152 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,17443256 0,22239185 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,17443256 0,22226864 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,17443256 0,22214557 ! vesicle targeting GO:0006903 32 23 0,000 0,17443256 0,22202263 ! osteoblast differentiation GO:0001649 40 23 0,000 0,17443256 0,22189983 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,17443256 0,22177717 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,17443256 0,22165464 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,17443256 0,22153225 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,17443256 0,22140999 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,17443256 0,22128786 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,17443256 0,22116588 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,17443256 0,22104402 ! cell fate determination GO:0001709 45 23 0,000 0,17443256 0,2209223 ! pentose metabolic process GO:0019321 31 23 0,000 0,17443256 0,22080071 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,17443256 0,22067926 ! spermatid development GO:0007286 33 23 0,000 0,17443256 0,22055794 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,17443256 0,22043676 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,17443256 0,2203157 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,17443256 0,22019478 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,17443256 0,220074 ! telomere organization GO:0032200 32 23 0,000 0,17443256 0,21995334 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,17443256 0,21983282 ! regulation of amine transport GO:0051952 38 23 0,000 0,17443256 0,21971243 ! liver development GO:0001889 40 23 0,000 0,17443256 0,21959217 ! response to virus GO:0009615 122 91 1,000 0,17444947 0,21949332 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,17741238 0,22309922 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,18128904 0,22784962 ! initiation of viral infection GO:0019059 42 24 0,000 0,18128904 0,22772518 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,18128904 0,22760087 ! superoxide metabolic process GO:0006801 32 24 0,000 0,18128904 0,22747671 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,18128904 0,22735267 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,18128904 0,22722877 ! fat cell differentiation GO:0045444 37 24 0,000 0,18128904 0,22710501 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,18128904 0,22698138 ! sperm motility GO:0030317 27 24 0,000 0,18128904 0,22685789 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,18128904 0,22673453 ! vacuole organization GO:0007033 39 24 0,000 0,18128904 0,22661131 ! receptor metabolic process GO:0043112 37 24 0,000 0,18128904 0,22648821 ! response to toxin GO:0009636 38 24 0,000 0,18128904 0,22636526 ! base-excision repair GO:0006284 31 24 0,000 0,18128904 0,22624243 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,18128904 0,22611974 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,18128904 0,22599718 ! glutathione metabolic process GO:0006749 29 24 0,000 0,18128904 0,22587476 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,18128904 0,22575246 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,18128904 0,2256303 ! response to oxidative stress GO:0006979 141 94 1,000 0,18336164 0,22808641 ! angiogenesis GO:0001525 149 95 1,000 0,18634733 0,23167506 ! carboxylic acid transport GO:0046942 147 95 1,000 0,18634733 0,2315499 GO:0015849|organic acid transport, ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,18808897 0,23358781 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,18808897 0,23346175 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,18808897 0,23333583 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,18808897 0,23321004 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,18808897 0,23308439 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,18808897 0,23295887 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,18808897 0,23283349 ! male gonad development GO:0008584 33 25 0,000 0,18808897 0,23270825 ! iron ion homeostasis GO:0055072 39 25 0,000 0,18808897 0,23258313 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,18808897 0,23245816 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,18808897 0,23233331 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,18808897 0,2322086 ! phospholipid transport GO:0015914 35 25 0,000 0,18808897 0,23208403 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,18808897 0,23195959 ! detection of light stimulus GO:0009583 30 25 0,000 0,18808897 0,23183528 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,18808897 0,2317111 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,18808897 0,23158706 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,18808897 0,23146315 ! in utero embryonic development GO:0001701 147 96 1,000 0,18933997 0,23287804 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,18933997 0,23275358 ! response to light stimulus GO:0009416 153 96 1,000 0,18933997 0,23262924 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,1948328 0,2392501 ! translational initiation GO:0006413 43 26 0,000 0,1948328 0,23912244 ! regulation of pH GO:0006885 36 26 0,000 0,1948328 0,2389949 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,1948328 0,23886751 ! post-embryonic development GO:0009791 42 26 0,000 0,1948328 0,23874025 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,1948328 0,23861312 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,1948328 0,23848613 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,1948328 0,23835928 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,1948328 0,23823256 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,1948328 0,23810598 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,1948328 0,23797952 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,1948328 0,23785321 ! regulation of coagulation GO:0050818 39 26 0,000 0,1948328 0,23772703 ! regulation of translation GO:0006417 151 100 1,000 0,20137371 0,2455777 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,20137371 0,24544756 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,20137371 0,24531755 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,201521 0,24536702 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,201521 0,2452372 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,201521 0,24510751 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,201521 0,24497796 ! membrane docking GO:0022406 39 27 0,000 0,201521 0,24484855 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,201521 0,24471928 ! catechol metabolic process GO:0009712 43 27 0,000 0,201521 0,24459014 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,201521 0,24446113 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,201521 0,24433227 ! myofibril assembly GO:0030239 36 27 0,000 0,201521 0,24420353 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,201521 0,24407494 ! response to ionizing radiation GO:0010212 47 27 0,000 0,201521 0,24394648 ! natural killer cell activation GO:0030101 35 27 0,000 0,201521 0,24381815 ! lipid oxidation GO:0034440 38 27 0,000 0,201521 0,24368996 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,201521 0,24356191 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,201521 0,24343399 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,201521 0,2433062 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,201521 0,24317855 GO:0043433|negative regulation of transcription factor activity, ! gene silencing GO:0016458 41 27 0,000 0,201521 0,24305103 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,20815403 0,25091943 ! phenol metabolic process GO:0018958 44 28 0,000 0,20815403 0,25078799 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,20815403 0,25065668 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,20815403 0,25052552 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,20815403 0,25039449 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,20815403 0,2502636 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,20815403 0,25013285 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,20815403 0,25000223 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,20815403 0,24987175 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,20815403 0,2497414 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,20815403 0,24961119 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,20815403 0,24948112 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,20815403 0,24935118 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,20815403 0,24922138 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,20815403 0,24909171 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,20815403 0,24896218 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,20815403 0,24883278 ! ensheathment of neurons GO:0007272 43 28 0,000 0,20815403 0,24870352 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,20815403 0,24857439 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,20815403 0,24844539 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,20815403 0,24831653 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,21473233 0,25603129 ! regulation of innate immune response GO:0045088 38 29 0,000 0,21473233 0,25589863 ! ovulation cycle process GO:0022602 41 29 0,000 0,21473233 0,25576611 ! protein targeting to membrane GO:0006612 53 29 0,000 0,21473233 0,25563373 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,21473233 0,25550148 ! mismatch repair GO:0006298 34 29 0,000 0,21473233 0,25536937 ! muscle cell development GO:0055001 38 29 0,000 0,21473233 0,25523739 ! eye morphogenesis GO:0048592 51 29 0,000 0,21473233 0,25510556 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,21473233 0,25497386 ! collagen metabolic process GO:0032963 40 30 0,000 0,22125636 0,26258494 ! organic anion transport GO:0015711 51 30 0,000 0,22125636 0,26244952 ! cholesterol transport GO:0030301 46 30 0,000 0,22125636 0,26231424 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,22125636 0,26217909 ! spindle organization GO:0007051 37 30 0,000 0,22125636 0,26204409 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,22125636 0,26190922 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,22125636 0,26177449 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,22125636 0,26163991 ! ceramide metabolic process GO:0006672 43 30 0,000 0,22125636 0,26150546 ! ovulation cycle GO:0042698 43 30 0,000 0,22125636 0,26137114 ! hindbrain development GO:0030902 45 30 0,000 0,22125636 0,26123697 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,22125636 0,26110293 ! adult locomotory behavior GO:0008344 47 30 0,000 0,22125636 0,26096903 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,22125636 0,26083527 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,22125636 0,26070165 ! response to heat GO:0009408 41 30 0,000 0,22125636 0,26056816 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,22125636 0,26043481 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,22125636 0,26030159 ! mammary gland development GO:0030879 57 31 0,000 0,22772655 0,26777662 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,22772655 0,26763979 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,22772655 0,2675031 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,22772655 0,26736655 ! odontogenesis GO:0042476 50 31 0,000 0,22772655 0,26723013 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,22772655 0,26709386 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,22772655 0,26695773 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,22772655 0,26682173 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,22772655 0,26668588 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,22772655 0,26655016 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,22772655 0,26641458 ! regulation of muscle development GO:0048634 48 32 0,000 0,23414335 0,27378226 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,23414335 0,27364315 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,23414335 0,27350417 ! meiosis I GO:0007127 52 32 0,000 0,23414335 0,27336534 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,23414335 0,27322664 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,23414335 0,27308809 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,23414335 0,27294968 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,23414335 0,2728114 ! regulation of protein stability GO:0031647 48 32 0,000 0,23414335 0,27267327 ! cytokine production GO:0001816 44 32 0,000 0,23414335 0,27253528 ! vesicle localization GO:0051648 47 32 0,000 0,23414335 0,27239743 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,24050721 0,27965954 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,24050721 0,27951823 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,24050721 0,27937706 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,24050721 0,27923603 ! sister chromatid segregation GO:0000819 46 33 0,000 0,24050721 0,27909514 ! ear morphogenesis GO:0042471 42 33 0,000 0,24050721 0,2789544 ! actomyosin structure organization GO:0031032 43 33 0,000 0,24050721 0,2788138 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,24050721 0,27867334 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,24050721 0,27853302 ! nucleus organization GO:0006997 49 33 0,000 0,24050721 0,27839284 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,24050721 0,2782528 ! female gonad development GO:0008585 49 33 0,000 0,24050721 0,27811291 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,24050721 0,27797315 ! positive regulation of cell development GO:0010720 54 33 0,000 0,24050721 0,27783354 ! lipid homeostasis GO:0055088 55 33 0,000 0,24050721 0,27769406 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,24050721 0,27755473 ! regulation of proteolysis GO:0030162 50 33 0,000 0,24050721 0,27741553 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,24050721 0,27727648 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,24050721 0,27713756 ! cytokinesis GO:0000910 52 33 0,000 0,24050721 0,27699878 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,24050721 0,27686015 ! mRNA catabolic process GO:0006402 48 34 0,000 0,24681854 0,28398331 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,24681854 0,28384132 ! feeding behavior GO:0007631 45 34 0,000 0,24681854 0,28369947 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,24681854 0,28355776 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,24681854 0,2834162 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,24681854 0,28327477 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,24681854 0,28313349 ! neuron migration GO:0001764 46 34 0,000 0,24681854 0,28299234 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,24681854 0,28285134 ! female gamete generation GO:0007292 43 34 0,000 0,24681854 0,28271048 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,24681854 0,28256976 ! polyol metabolic process GO:0019751 44 34 0,000 0,24681854 0,28242917 ! aerobic respiration GO:0009060 47 34 0,000 0,24681854 0,28228873 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,24681854 0,28214843 ! embryonic organ development GO:0048568 45 34 0,000 0,24681854 0,28200827 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,24681854 0,28186824 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,25307778 0,2888729 ! Notch signaling pathway GO:0007219 56 35 0,000 0,25307778 0,28872961 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,25307778 0,28858647 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,25307778 0,28844346 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,25307778 0,2883006 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,25307778 0,28815787 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,25307778 0,28801529 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,25307778 0,28787285 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,25307778 0,28773055 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,25307778 0,28758839 ! glycogen metabolic process GO:0005977 48 35 0,000 0,25307778 0,28744637 ! pigment metabolic process GO:0042440 61 35 0,000 0,25307778 0,28730449 ! protein homooligomerization GO:0051260 52 35 0,000 0,25307778 0,28716275 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,25928537 0,29406131 ! negative regulation of binding GO:0051100 58 36 0,000 0,25928537 0,29391639 ! organic ether metabolic process GO:0018904 46 36 0,000 0,25928537 0,2937716 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,25928537 0,29362696 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,25928537 0,29348245 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,25928537 0,29333809 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,25928537 0,29319388 ! glucan metabolic process GO:0044042 49 36 0,000 0,25928537 0,2930498 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,26544171 0,29986048 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,26544171 0,29971328 ! learning GO:0007612 67 37 0,000 0,26544171 0,29956621 ! ion transmembrane transport GO:0034220 56 37 0,000 0,26544171 0,2994193 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,26544171 0,29927252 ! amino acid activation GO:0043038 52 37 0,000 0,26544171 0,29912589 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,26544171 0,2989794 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,27154724 0,30570664 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,27154724 0,30555707 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,27154724 0,30540766 ! phagocytosis GO:0006909 60 38 0,000 0,27154724 0,30525839 ! pigmentation GO:0043473 74 38 0,000 0,27154724 0,30510926 ! maintenance of location in cell GO:0051651 69 38 0,000 0,27154724 0,30496028 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,27760237 0,31160832 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,27760237 0,31145632 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,27760237 0,31130446 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,27760237 0,31115276 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,27760237 0,3110012 ! male sex differentiation GO:0046661 53 39 0,000 0,27760237 0,31084978 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,27760237 0,31069852 ! chromatin remodeling GO:0006338 68 39 0,000 0,27760237 0,3105474 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,27760237 0,31039643 ! JNK cascade GO:0007254 54 39 0,000 0,27760237 0,3102456 ! developmental growth GO:0048589 62 39 0,000 0,27760237 0,31009493 ! cell growth GO:0016049 61 39 0,000 0,27760237 0,3099444 ! synapse organization GO:0050808 55 39 0,000 0,27760237 0,30979401 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,28360751 0,31634203 ! response to calcium ion GO:0051592 58 40 0,000 0,28360751 0,31618869 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,28360751 0,3160355 ! regulation of tube size GO:0035150 60 40 0,000 0,28360751 0,31588246 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,28360751 0,31572956 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,28360751 0,31557681 ! peptide metabolic process GO:0006518 56 40 0,000 0,28360751 0,31542421 ! inner ear development GO:0048839 57 40 0,000 0,28360751 0,31527176 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,28360751 0,31511946 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,28360751 0,3149673 ! B cell differentiation GO:0030183 62 40 0,000 0,28360751 0,31481529 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,28360751 0,31466342 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,28360751 0,3145117 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,28360751 0,31436013 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,28956307 0,32080687 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,28956307 0,32065242 ! glucose transport GO:0015758 52 41 0,000 0,28956307 0,32049811 ! endosome transport GO:0016197 71 41 0,000 0,28956307 0,32034395 ! striated muscle contraction GO:0006941 62 41 0,000 0,28956307 0,32018994 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,28956307 0,32003607 ! biopolymer methylation GO:0043414 62 41 0,000 0,28956307 0,31988236 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,28956307 0,31972879 ! mitochondrial transport GO:0006839 60 42 0,000 0,29546946 0,32609394 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,29546946 0,32593754 ! cellular component disassembly GO:0022411 64 42 0,000 0,29546946 0,32578129 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,29546946 0,32562519 ! hexose transport GO:0008645 54 42 0,000 0,29546946 0,32546924 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,29546946 0,32531344 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,29546946 0,32515778 ! excretion GO:0007588 63 42 0,000 0,29546946 0,32500228 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,29546946 0,32484692 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,29546946 0,32469172 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,29546946 0,32453666 ! regulation of cell shape GO:0008360 78 42 0,000 0,29546946 0,32438175 ! neuromuscular process GO:0050905 79 43 0,000 0,30132709 0,33065472 ! activation of caspase activity GO:0006919 65 43 0,000 0,30132709 0,33049704 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,30132709 0,33033951 ! tRNA processing GO:0008033 49 43 0,000 0,30132709 0,33018213 ! vesicle organization GO:0016050 79 43 0,000 0,30132709 0,3300249 ! methylation GO:0032259 64 43 0,000 0,30132709 0,32986782 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,30713634 0,33606735 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,30713634 0,33590755 ! regulation of action potential GO:0001508 71 44 0,000 0,30713634 0,3357479 ! regulation of ion transport GO:0043269 57 44 0,000 0,30713634 0,3355884 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,30713634 0,33542905 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,30713634 0,33526985 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,30713634 0,33511081 ! RNA catabolic process GO:0006401 64 45 0,000 0,31289762 0,34123496 ! regulation of translational initiation GO:0006446 64 45 0,000 0,31289762 0,34107324 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,31289762 0,34091167 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,31289762 0,34075025 ! cell recognition GO:0008037 58 45 0,000 0,31289762 0,34058899 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,31861132 0,3466443 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,31861132 0,3464804 ! cell redox homeostasis GO:0045454 63 46 0,000 0,31861132 0,34631666 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,31861132 0,34615307 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,32427784 0,35214307 ! viral infectious cycle GO:0019058 71 47 0,000 0,32427784 0,35197689 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,32427784 0,35181086 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,32427784 0,35164499 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,32427784 0,35147928 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,32427784 0,35131372 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,32427784 0,35114832 ! chloride transport GO:0006821 67 48 0,000 0,32989755 0,35706559 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,32989755 0,35689764 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,32989755 0,35672984 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,32989755 0,35656221 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,32989755 0,35639473 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,32989755 0,35622741 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,32989755 0,35606024 ! regulation of endocytosis GO:0030100 63 48 0,000 0,32989755 0,35589323 ! nuclear export GO:0051168 69 48 0,000 0,32989755 0,35572638 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,33547085 0,36156652 ! sensory perception of smell GO:0007608 61 49 0,000 0,33547085 0,36139717 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,33547085 0,36122798 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,33547085 0,36105894 ! germ cell development GO:0007281 68 49 0,000 0,33547085 0,36089006 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,33547085 0,36072134 ! maintenance of location GO:0051235 84 49 0,000 0,33547085 0,36055278 ! regulation of actin filament length GO:0030832 72 50 0,000 0,34099811 0,36632212 ! ear development GO:0043583 72 50 0,000 0,34099811 0,3661511 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,34099811 0,36598024 ! membrane fusion GO:0006944 80 50 0,000 0,34099811 0,36580954 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,34099811 0,365639 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,34099811 0,36546862 ! proton transport GO:0015992 75 50 0,000 0,34099811 0,36529839 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,34099811 0,36512833 ! hydrogen transport GO:0006818 77 51 0,000 0,34647971 0,37082519 ! muscle fiber development GO:0048747 74 51 0,000 0,34647971 0,37065271 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,34647971 0,3704804 ! adult behavior GO:0030534 80 51 0,000 0,34647971 0,37030824 ! transition metal ion transport GO:0000041 74 52 0,000 0,35191603 0,37594374 ! regulation of cellular component size GO:0032535 74 52 0,000 0,35191603 0,3757692 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,35191603 0,37559483 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,35191603 0,37542062 ! establishment of organelle localization GO:0051656 85 52 0,000 0,35191603 0,37524658 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,35730743 0,38081886 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,35730743 0,38064247 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,36265429 0,38615966 ! DNA catabolic process GO:0006308 67 54 0,000 0,36265429 0,38598097 ! detection of external stimulus GO:0009581 66 54 0,000 0,36265429 0,38580244 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,36265429 0,38562407 ! exocytosis GO:0006887 74 55 0,000 0,36795697 0,39108181 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,36795697 0,39090117 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,37321584 0,39630491 ! carbohydrate transport GO:0008643 74 57 0,000 0,37843125 0,40165753 ! chromosome segregation GO:0007059 83 57 0,000 0,37843125 0,40147226 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,37843125 0,40128717 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,37843125 0,40110224 ! camera-type eye development GO:0043010 88 57 0,000 0,37843125 0,40091749 ! secondary metabolic process GO:0019748 84 57 0,000 0,37843125 0,4007329 ! gonad development GO:0008406 79 57 0,000 0,37843125 0,40054849 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,38360356 0,40583633 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,38873312 0,4110741 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,38873312 0,41088519 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,38873312 0,41069645 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,39382028 0,41588001 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,39382028 0,41568915 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,39382028 0,41549846 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,39382028 0,41530796 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,39382028 0,41511762 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,39382028 0,41492746 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,3988654 0,42005056 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,3988654 0,41985832 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,3988654 0,41966625 ! extracellular matrix organization GO:0030198 103 61 0,000 0,3988654 0,41947436 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,3988654 0,41928264 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,3988654 0,4190911 ! amine catabolic process GO:0009310 90 62 0,000 0,40386882 0,42415447 ! neurotransmitter transport GO:0006836 81 62 0,000 0,40386882 0,42396088 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,40386882 0,42376746 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,40386882 0,42357423 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,40386882 0,42338117 ! organelle localization GO:0051640 96 62 0,000 0,40386882 0,42318828 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,40883087 0,42819263 ! appendage morphogenesis GO:0035107 93 64 0,000 0,41375191 0,43314947 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,41375191 0,43295241 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,41375191 0,43275552 ! adaptive immune response GO:0002250 94 64 0,000 0,41375191 0,43255882 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 0,000 0,41863226 0,43746216 ! appendage development GO:0048736 94 65 0,000 0,41863226 0,43726349 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,41863226 0,437065 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,41863226 0,4368667 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,41863226 0,43666857 ! activation of immune response GO:0002253 83 65 0,000 0,41863226 0,43647063 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,42347227 0,44131681 ! antigen processing and presentation GO:0019882 96 66 0,000 0,42347227 0,44111694 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,42347227 0,44091725 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,42827225 0,4457132 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,42827225 0,44551161 ! learning or memory GO:0007611 123 68 0,000 0,43303254 0,45025988 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,43303254 0,45005642 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,43303254 0,44985314 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,43303254 0,44965004 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,43303254 0,44944713 ! inorganic anion transport GO:0015698 93 68 0,000 0,43303254 0,44924441 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,43775347 0,45393733 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,43775347 0,45373276 ! response to drug GO:0042493 108 69 0,000 0,43775347 0,45352837 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,43775347 0,45332417 ! response to metal ion GO:0010038 103 70 0,000 0,44243536 0,4579664 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,44243536 0,45776038 ! eye development GO:0001654 111 70 0,000 0,44243536 0,45755456 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,44707853 0,4621486 ! muscle cell differentiation GO:0042692 104 71 0,000 0,44707853 0,46194098 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,44707853 0,46173355 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,44707853 0,46152631 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,4516833 0,4660707 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,4516833 0,4658617 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,4516833 0,46565289 ! regulation of blood pressure GO:0008217 107 73 0,000 0,45624998 0,47015007 ! mitochondrion organization GO:0007005 104 73 0,000 0,45624998 0,46993952 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,45624998 0,46972917 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,46077889 0,47417962 ! digestion GO:0007586 97 74 0,000 0,46077889 0,47396755 ! response to inorganic substance GO:0010035 115 75 0,000 0,46527033 0,47837361 ! response to nutrient GO:0007584 104 75 0,000 0,46527033 0,47815986 ! regulation of ligase activity GO:0051340 114 75 0,000 0,46527033 0,4779463 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,46527033 0,47773293 ! amine biosynthetic process GO:0009309 97 76 0,000 0,46972462 0,48209131 ! tRNA metabolic process GO:0006399 95 76 0,000 0,46972462 0,48187629 ! response to unfolded protein GO:0006986 99 76 0,000 0,46972462 0,48166145 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,46972462 0,48144681 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,47414206 0,48575801 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,47414206 0,48554174 ! sex differentiation GO:0007548 105 77 0,000 0,47414206 0,48532565 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,47414206 0,48510976 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,47414206 0,48489406 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,47852295 0,48915679 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,47852295 0,48893949 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,48286759 0,49315962 ! cellular respiration GO:0045333 107 79 0,000 0,48286759 0,49294073 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,48286759 0,49272204 ! regulation of lyase activity GO:0051339 133 79 0,000 0,48286759 0,49250353 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,48286759 0,49228523 ! chromatin assembly GO:0031497 102 80 0,000 0,48717629 0,49645789 GO:0006334|nucleosome assembly, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,48717629 0,49623803 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,48717629 0,49601836 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,49144933 0,50014755 ! mRNA transport GO:0051028 121 81 0,000 0,49144933 0,49992634 ! response to protein stimulus GO:0051789 111 81 0,000 0,49144933 0,49970533 ! regulation of neurological system process GO:0031644 122 81 0,000 0,49144933 0,49948451 ! detection of stimulus GO:0051606 108 82 0,000 0,49568701 0,50356896 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,49988962 0,50761418 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,50405744 0,51162053 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,50405744 0,51139485 ! sterol metabolic process GO:0016125 120 84 0,000 0,50405744 0,51116936 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,50819077 0,51513388 ! rRNA metabolic process GO:0016072 107 85 0,000 0,50819077 0,51490695 GO:0006364|rRNA processing, ! regulation of membrane potential GO:0042391 128 85 0,000 0,50819077 0,51468022 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,51228989 0,51860332 ! nucleosome organization GO:0034728 114 87 0,000 0,51635507 0,52248864 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,51635507 0,52225887 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,51635507 0,52202931 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,52038661 0,52587399 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,52038661 0,52564304 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,52038661 0,52541229 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,52038661 0,52518174 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,52438476 0,52898463 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,52438476 0,52875272 ! RNA localization GO:0006403 135 91 0,000 0,53228205 0,53648059 ! ATP metabolic process GO:0046034 137 91 0,000 0,53228205 0,5362456 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,53618171 0,5399378 ! positive regulation of immune response GO:0050778 121 92 0,000 0,53618171 0,5397015 ! DNA recombination GO:0006310 146 92 0,000 0,53618171 0,53946541 ! sulfur metabolic process GO:0006790 118 92 0,000 0,53618171 0,53922953 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,54004909 0,54288151 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,54004909 0,54264434 ! electron transport chain GO:0022900 123 94 0,000 0,54388444 0,54625948 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,55146011 0,55362647 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,55146011 0,55338492 ! protein maturation GO:0051604 129 96 0,000 0,55146011 0,55314359 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,55520095 0,55665309 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,55520095 0,55641054 ! calcium ion transport GO:0006816 167 99 0,000 0,56258993 0,56357005 ! extracellular structure organization GO:0043062 156 99 0,000 0,56258993 0,5633247 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,56623858 0,56673139 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,56623858 0,56648488 ! divalent metal ion transport GO:0070838 171 100 0,000 0,56623858 0,56623858