pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6202-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! posttranscriptional regulation of gene expression GO:0010608 98 98 6,000 6,743E-08 1,243E-04 ! regulation of translation GO:0006417 69 69 5,000 2,046E-07 1,885E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 1,067E-06 6,555E-04 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 2,98E-06 1,373E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 3,612E-06 1,332E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 4,179E-06 1,284E-03 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 4,778E-06 1,258E-03 ! regulation of translational initiation GO:0006446 31 31 3,000 5,507E-06 1,269E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 5,507E-06 1,128E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 6,352E-06 1,171E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 8,711E-06 1,46E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 1,017E-05 1,562E-03 ! protein oligomerization GO:0051259 39 39 3,000 1,409E-05 1,998E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,409E-05 1,855E-03 ! positive regulation of DNA replication GO:0045740 14 13 2,000 1,502E-05 1,846E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,502E-05 1,73E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,502E-05 1,628E-03 ! regulation of caspase activity GO:0043281 41 41 3,000 1,726E-05 1,767E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,765E-05 1,712E-03 ! heart development GO:0007507 90 87 4,000 1,867E-05 1,721E-03 ! regulation of endopeptidase activity GO:0052548 42 42 3,000 1,902E-05 1,669E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,907E-05 1,597E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,975E-05 1,582E-03 GO:0033674|positive regulation of kinase activity, ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 2,377E-05 1,825E-03 ! regulation of peptidase activity GO:0052547 46 46 3,000 2,744E-05 2,023E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 3,534E-05 2,505E-03 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 3,534E-05 2,412E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 3,831E-05 2,521E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 4,23E-05 2,688E-03 ! B cell differentiation GO:0030183 18 18 2,000 4,23E-05 2,599E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 6,84E-05 4,067E-03 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 6,84E-05 3,94E-03 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 7,9E-05 4,412E-03 ! positive regulation of growth GO:0045927 23 23 2,000 9,061E-05 4,912E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,171E-04 6,164E-03 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 1,171E-04 5,993E-03 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 1,218E-04 6,067E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 1,32E-04 6,401E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,473E-04 6,959E-03 ! mRNA stabilization GO:0048255 5 5 1,000 1,473E-04 6,785E-03 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 1,473E-04 6,619E-03 ! tyrosine metabolic process GO:0006570 5 5 1,000 1,473E-04 6,462E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,473E-04 6,311E-03 ! corticosteroid receptor signaling pathway GO:0031958 5 5 1,000 1,473E-04 6,168E-03 GO:0042921|glucocorticoid receptor signaling pathway, ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 1,473E-04 6,031E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,473E-04 5,9E-03 ! positive regulation of phagocytosis GO:0050766 5 5 1,000 1,473E-04 5,774E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,473E-04 5,654E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,473E-04 5,539E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,473E-04 5,428E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,473E-04 5,321E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,481E-04 5,249E-03 ! regulation of cell migration GO:0030334 71 71 3,000 1,528E-04 5,312E-03 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,84E-04 6,281E-03 ! response to UV GO:0009411 29 29 2,000 1,84E-04 6,167E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,203E-04 7,252E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,203E-04 7,124E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 2,203E-04 7,002E-03 GO:0050927|positive regulation of positive chemotaxis, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 2,203E-04 6,883E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,203E-04 6,768E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 2,203E-04 6,657E-03 ! ER overload response GO:0006983 6 6 1,000 2,203E-04 6,55E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,203E-04 6,446E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 2,203E-04 6,345E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 2,203E-04 6,248E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,203E-04 6,153E-03 ! regulation of phagocytosis GO:0050764 6 6 1,000 2,203E-04 6,061E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,203E-04 5,972E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,203E-04 5,885E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,203E-04 5,801E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,203E-04 5,72E-03 ! localization within membrane GO:0051668 6 6 1,000 2,203E-04 5,64E-03 ! B cell activation GO:0042113 31 31 2,000 2,252E-04 5,686E-03 ! aging GO:0007568 32 31 2,000 2,252E-04 5,609E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 2,252E-04 5,534E-03 ! regulation of locomotion GO:0040012 79 79 3,000 2,312E-04 5,607E-03 ! regulation of cell motion GO:0051270 79 79 3,000 2,312E-04 5,534E-03 ! maintenance of location GO:0051235 33 32 2,000 2,479E-04 5,856E-03 ! regulation of bone remodeling GO:0046850 34 34 2,000 2,975E-04 6,94E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 3,077E-04 7,089E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 3,077E-04 7,002E-03 ! axis specification GO:0009798 7 7 1,000 3,077E-04 6,917E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,077E-04 6,833E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 3,077E-04 6,752E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,077E-04 6,672E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 3,077E-04 6,595E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 3,077E-04 6,519E-03 ! regulation of mRNA stability GO:0043488 7 7 1,000 3,077E-04 6,445E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,077E-04 6,373E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 3,245E-04 6,645E-03 ! regulation of tissue remodeling GO:0034103 35 35 2,000 3,245E-04 6,572E-03 ! lung development GO:0030324 38 37 2,000 3,832E-04 7,677E-03 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,832E-04 7,595E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 4,093E-04 8,025E-03 ! sex determination GO:0007530 8 8 1,000 4,093E-04 7,941E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 4,093E-04 7,858E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 4,093E-04 7,777E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 4,093E-04 7,698E-03 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 4,093E-04 7,62E-03 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 4,093E-04 7,544E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 4,093E-04 7,469E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 4,093E-04 7,396E-03 ! regulation of homeostatic process GO:0032844 38 38 2,000 4,15E-04 7,426E-03 ! activation of MAPK activity GO:0000187 39 39 2,000 4,484E-04 7,946E-03 ! respiratory tube development GO:0030323 40 39 2,000 4,484E-04 7,871E-03 ! respiratory system development GO:0060541 40 39 2,000 4,484E-04 7,796E-03 ! lymphocyte differentiation GO:0030098 39 39 2,000 4,484E-04 7,723E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 5,25E-04 8,959E-03 ! cortical actin cytoskeleton organization GO:0030866 10 9 1,000 5,25E-04 8,877E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 5,25E-04 8,796E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 5,25E-04 8,717E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 5,25E-04 8,639E-03 ! pigmentation during development GO:0048066 9 9 1,000 5,25E-04 8,563E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 5,25E-04 8,487E-03 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 5,25E-04 8,414E-03 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 5,25E-04 8,341E-03 ! regulation of cellular pH GO:0030641 9 9 1,000 5,25E-04 8,27E-03 ! histone acetylation GO:0016573 9 9 1,000 5,25E-04 8,2E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 5,25E-04 8,131E-03 ! regulation of leukocyte migration GO:0002685 9 9 1,000 5,25E-04 8,063E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 5,25E-04 7,996E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 5,704E-04 8,617E-03 ! hemopoiesis GO:0030097 104 100 3,000 5,704E-04 8,547E-03 ! mitochondrion organization GO:0007005 44 43 2,000 5,992E-04 8,906E-03 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 6,547E-04 9,652E-03 ! cortical cytoskeleton organization GO:0030865 11 10 1,000 6,547E-04 9,576E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 6,547E-04 9,5E-03 ! cell-substrate junction assembly GO:0007044 11 10 1,000 6,547E-04 9,426E-03 ! neuromuscular junction development GO:0007528 10 10 1,000 6,547E-04 9,353E-03 ! protein export from nucleus GO:0006611 10 10 1,000 6,547E-04 9,281E-03 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 6,547E-04 9,21E-03 ! negative regulation of neuron differentiation GO:0045665 10 10 1,000 6,547E-04 9,14E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 6,547E-04 9,072E-03 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 6,547E-04 9,004E-03 ! protein stabilization GO:0050821 10 10 1,000 6,547E-04 8,937E-03 ! regulation of DNA binding GO:0051101 47 45 2,000 6,854E-04 9,288E-03 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 7,982E-04 0,0107378 ! skin development GO:0043588 11 11 1,000 7,982E-04 0,01065999 ! protein amino acid acetylation GO:0006473 11 11 1,000 7,982E-04 0,0105833 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 7,982E-04 0,01050771 GO:0032388|positive regulation of intracellular transport, ! cellular response to starvation GO:0009267 11 11 1,000 7,982E-04 0,01043318 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 7,982E-04 0,01035971 ! G1/S transition checkpoint GO:0031575 12 11 1,000 7,982E-04 0,01028726 ! interaction with host GO:0051701 11 11 1,000 7,982E-04 0,01021582 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 7,982E-04 0,01014537 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 7,982E-04 0,01007588 GO:0006109|regulation of carbohydrate metabolic process, ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 7,982E-04 0,01000734 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 7,982E-04 9,94E-03 ! regulation of cell cycle process GO:0010564 50 48 2,000 8,289E-04 0,01025263 ! leukocyte differentiation GO:0002521 50 49 2,000 8,806E-04 0,01082015 ! cell cycle arrest GO:0007050 49 49 2,000 8,806E-04 0,01074849 ! skeletal muscle tissue development GO:0007519 50 49 2,000 8,806E-04 0,01067778 GO:0060538|skeletal muscle organ development, ! regulation of neurogenesis GO:0050767 51 50 2,000 9,344E-04 0,01125564 ! translational initiation GO:0006413 12 12 1,000 9,555E-04 0,01143522 ! heterophilic cell adhesion GO:0007157 12 12 1,000 9,555E-04 0,01136145 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 9,555E-04 0,01128862 ! positive regulation of endocytosis GO:0045807 12 12 1,000 9,555E-04 0,01121672 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 1,000 9,555E-04 0,01114572 ! somitogenesis GO:0001756 13 12 1,000 9,555E-04 0,01107563 ! G1 phase GO:0051318 13 12 1,000 9,555E-04 0,0110064 ! negative regulation of translation GO:0017148 12 12 1,000 9,555E-04 0,01093804 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 9,555E-04 0,01087052 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 9,902E-04 0,01119614 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 2,000 1,048E-03 0,01177835 ! response to light stimulus GO:0009416 53 52 2,000 1,048E-03 0,01170697 ! response to hypoxia GO:0001666 53 53 2,000 1,108E-03 0,01230245 ! regulation of protein transport GO:0051223 53 53 2,000 1,108E-03 0,01222878 GO:0070201|regulation of establishment of protein localization, ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 1,127E-03 0,0123582 ! vasculogenesis GO:0001570 13 13 1,000 1,127E-03 0,01228507 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,127E-03 0,01221281 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,127E-03 0,01214139 ! cell aging GO:0007569 13 13 1,000 1,127E-03 0,0120708 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,127E-03 0,01200103 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 1,127E-03 0,01193205 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,127E-03 0,01186387 ! positive regulation of locomotion GO:0040017 13 13 1,000 1,127E-03 0,01179646 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 1,127E-03 0,01172982 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,127E-03 0,01166392 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,127E-03 0,01159876 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,127E-03 0,01153432 GO:0001952|regulation of cell-matrix adhesion, ! activation of JUN kinase activity GO:0007257 13 13 1,000 1,127E-03 0,01147059 ! response to oxygen levels GO:0070482 55 54 2,000 1,17E-03 0,01184997 ! regulation of cell adhesion GO:0030155 56 55 2,000 1,234E-03 0,01243261 ! regulation of nervous system development GO:0051960 57 56 2,000 1,301E-03 0,01303086 ! protein amino acid acylation GO:0043543 14 14 1,000 1,311E-03 0,01306135 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 1,311E-03 0,01299113 ! regulation of behavior GO:0050795 14 14 1,000 1,311E-03 0,01292166 ! base-excision repair GO:0006284 14 14 1,000 1,311E-03 0,01285293 ! regulation of binding GO:0051098 60 57 2,000 1,37E-03 0,01335598 ! regulation of protein localization GO:0032880 58 57 2,000 1,37E-03 0,01328569 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,509E-03 0,01456207 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 1,509E-03 0,01448623 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,509E-03 0,01441117 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 1,000 1,509E-03 0,01433689 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,509E-03 0,01426337 ! response to starvation GO:0042594 15 15 1,000 1,509E-03 0,01419059 ! response to ionizing radiation GO:0010212 16 15 1,000 1,509E-03 0,01411856 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,509E-03 0,01404725 ! protein homooligomerization GO:0051260 15 15 1,000 1,509E-03 0,01397666 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 1,514E-03 0,01394981 ! regulation of cell development GO:0060284 60 59 2,000 1,514E-03 0,01388041 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 1,667E-03 0,01521097 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,721E-03 0,01562074 ! segmentation GO:0035282 17 16 1,000 1,721E-03 0,01554417 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,721E-03 0,01546834 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,721E-03 0,01539325 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 1,721E-03 0,01531889 GO:0043507|positive regulation of JUN kinase activity, ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 1,945E-03 0,01723619 ! myelination GO:0042552 17 17 1,000 1,945E-03 0,01715372 ! leukocyte adhesion GO:0007159 17 17 1,000 1,945E-03 0,01707203 ! cell junction assembly GO:0034329 18 17 1,000 1,945E-03 0,01699112 ! tissue remodeling GO:0048771 17 17 1,000 1,945E-03 0,01691098 ! negative regulation of cell development GO:0010721 18 17 1,000 1,945E-03 0,01683158 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,945E-03 0,01675293 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 1,945E-03 0,01667501 ! pigmentation GO:0043473 17 17 1,000 1,945E-03 0,01659781 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,183E-03 0,01854158 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,183E-03 0,01845653 ! negative regulation of DNA binding GO:0043392 19 18 1,000 2,183E-03 0,01837225 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,183E-03 0,01828874 ! ensheathment of neurons GO:0007272 18 18 1,000 2,183E-03 0,01820599 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,183E-03 0,01812398 ! striated muscle tissue development GO:0014706 69 67 2,000 2,185E-03 0,01805509 ! response to radiation GO:0009314 70 68 2,000 2,28E-03 0,01875506 ! regulation of cell size GO:0008361 68 68 2,000 2,28E-03 0,01867171 ! regionalization GO:0003002 70 69 2,000 2,377E-03 0,01938339 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 2,377E-03 0,01929801 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,434E-03 0,01967551 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,434E-03 0,01958959 ! regulation of pH GO:0006885 19 19 1,000 2,434E-03 0,01950442 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 2,434E-03 0,01941998 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 2,434E-03 0,01933628 ! peripheral nervous system development GO:0007422 19 19 1,000 2,434E-03 0,01925329 ! regulation of protein stability GO:0031647 19 19 1,000 2,434E-03 0,01917101 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 2,434E-03 0,01908943 ! regulation of cell shape GO:0008360 21 19 1,000 2,434E-03 0,01900854 ! positive regulation of transport GO:0051050 71 70 2,000 2,477E-03 0,01926104 ! wound healing GO:0042060 74 70 2,000 2,477E-03 0,01918011 ! muscle tissue development GO:0060537 72 70 2,000 2,477E-03 0,01909986 ! negative regulation of signal transduction GO:0009968 71 71 2,000 2,579E-03 0,01980765 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 2,685E-03 0,02052946 ! negative regulation of binding GO:0051100 21 20 1,000 2,698E-03 0,02054721 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,698E-03 0,02046265 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 2,698E-03 0,02037879 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,975E-03 0,02237783 ! mammary gland development GO:0030879 23 21 1,000 2,975E-03 0,02228686 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,975E-03 0,02219663 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,975E-03 0,02210713 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 2,975E-03 0,02201834 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,975E-03 0,02193027 ! negative regulation of cell communication GO:0010648 76 76 2,000 3,132E-03 0,02299357 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 3,264E-03 0,02387407 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 3,264E-03 0,02377971 ! maintenance of protein location in cell GO:0032507 23 22 1,000 3,264E-03 0,02368608 ! pigment biosynthetic process GO:0046148 22 22 1,000 3,264E-03 0,0235932 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 3,264E-03 0,02350104 ! regulation of protein modification process GO:0031399 79 78 2,000 3,371E-03 0,02417541 ! nuclear transport GO:0051169 79 79 2,000 3,495E-03 0,0249671 GO:0006913|nucleocytoplasmic transport, ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 3,567E-03 0,02537969 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 3,567E-03 0,02528207 ! calcium-mediated signaling GO:0019722 23 23 1,000 3,567E-03 0,02518521 ! regulation of JNK cascade GO:0046328 25 23 1,000 3,567E-03 0,02508908 ! MAPKKK cascade GO:0000165 82 81 2,000 3,751E-03 0,02628795 ! tube development GO:0035295 83 81 2,000 3,751E-03 0,02618838 ! lymphocyte activation GO:0046649 82 81 2,000 3,751E-03 0,02608955 ! mitochondrial transport GO:0006839 24 24 1,000 3,882E-03 0,02689327 ! regulation of action potential GO:0001508 24 24 1,000 3,882E-03 0,02679255 ! gliogenesis GO:0042063 24 24 1,000 3,882E-03 0,02669258 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 3,882E-03 0,02659335 ! glucose homeostasis GO:0042593 24 24 1,000 3,882E-03 0,02649486 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 3,882E-03 0,02639709 ! maintenance of protein location GO:0045185 25 24 1,000 3,882E-03 0,02630004 ! regulation of T cell proliferation GO:0042129 25 25 1,000 4,209E-03 0,02841357 ! positive regulation of DNA binding GO:0043388 26 25 1,000 4,209E-03 0,02830987 ! heart morphogenesis GO:0003007 25 25 1,000 4,209E-03 0,02820692 ! regulation of endocytosis GO:0030100 25 25 1,000 4,209E-03 0,02810473 ! negative regulation of immune system process GO:0002683 25 25 1,000 4,209E-03 0,02800326 ! regulation of cellular localization GO:0060341 86 85 2,000 4,298E-03 0,02849134 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 4,441E-03 0,02933876 ! positive regulation of binding GO:0051099 27 26 1,000 4,549E-03 0,02993944 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 4,549E-03 0,02983289 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,549E-03 0,0297271 ! double-strand break repair GO:0006302 27 26 1,000 4,549E-03 0,02962206 ! pigment metabolic process GO:0042440 26 26 1,000 4,549E-03 0,02951776 ! response to insulin stimulus GO:0032868 28 26 1,000 4,549E-03 0,02941419 ! maintenance of location in cell GO:0051651 27 26 1,000 4,549E-03 0,02931134 ! synapse organization GO:0050808 26 26 1,000 4,549E-03 0,02920921 ! learning or memory GO:0007611 28 27 1,000 4,901E-03 0,0313606 ! activation of caspase activity GO:0006919 27 27 1,000 4,901E-03 0,03125208 ! negative regulation of cell cycle GO:0045786 92 91 2,000 5,204E-03 0,03307244 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 5,265E-03 0,03334418 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 1,000 5,265E-03 0,03322999 ! histone modification GO:0016570 28 28 1,000 5,265E-03 0,03311658 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 5,265E-03 0,03300393 ! viral reproductive process GO:0022415 29 29 1,000 5,641E-03 0,03524334 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 5,641E-03 0,03512427 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 1,000 5,641E-03 0,03500601 ! covalent chromatin modification GO:0016569 29 29 1,000 5,641E-03 0,03488854 ! positive regulation of protein transport GO:0051222 29 29 1,000 5,641E-03 0,03477186 ! pattern specification process GO:0007389 96 94 2,000 5,697E-03 0,03500042 ! epidermis development GO:0008544 94 94 2,000 5,697E-03 0,03488414 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 6,03E-03 0,03679657 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 6,03E-03 0,03667513 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 6,03E-03 0,03655449 ! regulation of ossification GO:0030278 30 30 1,000 6,03E-03 0,03643464 ! vascular process in circulatory system GO:0003018 31 30 1,000 6,03E-03 0,03631557 ! regulation of cell growth GO:0001558 97 96 2,000 6,041E-03 0,03626751 ! skeletal muscle fiber development GO:0048741 31 31 1,000 6,43E-03 0,03847508 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 6,43E-03 0,03835056 ! epidermal cell differentiation GO:0009913 31 31 1,000 6,43E-03 0,03822685 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 6,43E-03 0,03810393 ! ectoderm development GO:0007398 99 99 2,000 6,58E-03 0,03887037 ! muscle organ development GO:0007517 102 100 2,000 6,766E-03 0,03984065 ! negative regulation of cell growth GO:0030308 32 32 1,000 6,842E-03 0,04015889 ! muscle fiber development GO:0048747 32 32 1,000 6,842E-03 0,0400314 ! regulation of phospholipase activity GO:0010517 32 32 1,000 6,842E-03 0,03990472 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 6,842E-03 0,03977884 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 6,842E-03 0,03965375 ! nuclear export GO:0051168 32 32 1,000 6,842E-03 0,03952944 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,842E-03 0,03940591 ! positive regulation of lipase activity GO:0060193 32 32 1,000 6,842E-03 0,03928315 ! negative regulation of cell size GO:0045792 33 33 1,000 7,266E-03 0,04158726 ! regulation of cellular response to stress GO:0080135 35 33 1,000 7,266E-03 0,04145851 ! regulation of neuron differentiation GO:0045664 34 33 1,000 7,266E-03 0,04133055 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 7,266E-03 0,04120338 ! regulation of angiogenesis GO:0045765 35 34 1,000 7,701E-03 0,0435392 ! secondary metabolic process GO:0019748 34 34 1,000 7,701E-03 0,04340605 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 7,701E-03 0,04327371 ! viral reproduction GO:0016032 34 34 1,000 7,701E-03 0,04314218 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 8,149E-03 0,04550837 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 8,149E-03 0,04537088 ! regulation of mitosis GO:0007088 37 36 1,000 8,607E-03 0,04777976 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 8,607E-03 0,04763628 GO:0045937|positive regulation of phosphate metabolic process, ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 8,607E-03 0,04749365 ! regulation of lipase activity GO:0060191 36 36 1,000 8,607E-03 0,04735188 ! regulation of transcription factor activity GO:0051090 38 37 1,000 9,077E-03 0,0497886 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 9,077E-03 0,04964086 ! response to drug GO:0042493 37 37 1,000 9,077E-03 0,049494 ! negative regulation of growth GO:0045926 37 37 1,000 9,077E-03 0,049348 ! adaptive immune response GO:0002250 37 37 1,000 9,077E-03 0,04920286 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 38 38 1,000 9,558E-03 0,05165944 ! axon guidance GO:0007411 39 38 1,000 9,558E-03 0,05150838 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 9,558E-03 0,05135821 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01005068 0,05384711 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,01005068 0,05369103 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,01055422 0,05621799 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01055422 0,05605598 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01106878 0,05861999 ! protein ubiquitination GO:0016567 43 42 1,000 0,01159427 0,06122707 ! humoral immune response GO:0006959 44 44 1,000 0,01267773 0,06675728 ! protein import into nucleus GO:0006606 44 44 1,000 0,01267773 0,06656709 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,01323551 0,06929841 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01323551 0,0691021 ! nuclear import GO:0051170 45 45 1,000 0,01323551 0,0689069 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01380388 0,07166353 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01380388 0,07146223 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,01438276 0,07425049 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01438276 0,07404309 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01497206 0,07686213 ! ossification GO:0001503 50 49 1,000 0,01557169 0,07971842 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01557169 0,07949759 ! negative regulation of transport GO:0051051 51 50 1,000 0,01618158 0,08238302 ! chromatin assembly GO:0031497 50 50 1,000 0,01618158 0,08215607 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 1,000 0,01618158 0,08193036 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01618158 0,0817059 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01680164 0,08460496 ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,01680164 0,08437443 ! protein maturation GO:0051604 51 51 1,000 0,01680164 0,08414515 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01807192 0,09026166 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01872199 0,09325574 ! nucleosome organization GO:0034728 55 55 1,000 0,01938189 0,09628256 ! in utero embryonic development GO:0001701 55 55 1,000 0,01938189 0,09602374 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,01938189 0,0957663 ! rRNA transcription GO:0009303 5 5 0,000 0,0194743 0,09596562 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0194743 0,09570971 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0194743 0,09545516 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0194743 0,09520196 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0194743 0,09495011 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0194743 0,09469958 ! reproductive cellular process GO:0048610 5 5 0,000 0,0194743 0,09445037 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0194743 0,09420247 ! prostate gland development GO:0030850 5 5 0,000 0,0194743 0,09395587 ! metencephalon development GO:0022037 5 5 0,000 0,0194743 0,09371055 ! water transport GO:0006833 5 5 0,000 0,0194743 0,09346651 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0194743 0,09322374 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0194743 0,09298223 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0194743 0,09274197 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0194743 0,09250294 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0194743 0,09226514 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0194743 0,09202857 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0194743 0,0917932 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0194743 0,09155903 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0194743 0,09132606 ! filopodium assembly GO:0046847 7 5 0,000 0,0194743 0,09109427 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0194743 0,09086365 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0194743 0,09063419 ! GTP metabolic process GO:0046039 5 5 0,000 0,0194743 0,0904059 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0194743 0,09017875 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0194743 0,08995273 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0194743 0,08972785 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0194743 0,08950409 ! social behavior GO:0035176 5 5 0,000 0,0194743 0,08928144 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0194743 0,0890599 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0194743 0,08883946 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0194743 0,0886201 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0194743 0,08840182 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0194743 0,08818462 ! response to lipid GO:0033993 5 5 0,000 0,0194743 0,08796848 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0194743 0,0877534 ! hippocampus development GO:0021766 6 5 0,000 0,0194743 0,08753937 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0194743 0,08732638 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0194743 0,08711442 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0194743 0,08690349 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0194743 0,08669358 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0194743 0,08648468 ! heart looping GO:0001947 5 5 0,000 0,0194743 0,08627678 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0194743 0,08606988 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0194743 0,08586397 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0194743 0,08565905 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0194743 0,0854551 ! pH reduction GO:0045851 5 5 0,000 0,0194743 0,08525212 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0194743 0,0850501 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0194743 0,08484903 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0194743 0,08464892 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0194743 0,08444974 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0194743 0,0842515 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0194743 0,08405419 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0194743 0,08385781 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0194743 0,08366233 ! adrenal gland development GO:0030325 5 5 0,000 0,0194743 0,08346777 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0194743 0,08327411 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0194743 0,08308134 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0194743 0,08288947 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0194743 0,08269848 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0194743 0,08250837 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0194743 0,08231913 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0194743 0,08213076 GO:0033135|regulation of peptidyl-serine phosphorylation, ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0194743 0,08194324 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0194743 0,08175658 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0194743 0,08157077 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0194743 0,08138581 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0194743 0,08120168 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0194743 0,08101838 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0194743 0,0808359 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0194743 0,08065425 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0194743 0,08047341 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0194743 0,08029338 ! response to ATP GO:0033198 5 5 0,000 0,0194743 0,08011415 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0194743 0,07993573 ! regulation of appetite GO:0032098 5 5 0,000 0,0194743 0,07975809 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0194743 0,07958124 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0194743 0,07940518 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0194743 0,07922989 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0194743 0,07905538 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0194743 0,07888163 ! receptor clustering GO:0043113 5 5 0,000 0,0194743 0,07870864 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0194743 0,07853641 ! fear response GO:0042596 5 5 0,000 0,0194743 0,07836494 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0194743 0,07819421 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0194743 0,07802422 ! retinol metabolic process GO:0042572 5 5 0,000 0,0194743 0,07785497 ! temperature homeostasis GO:0001659 5 5 0,000 0,0194743 0,07768645 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0194743 0,07751866 ! parturition GO:0007567 5 5 0,000 0,0194743 0,0773516 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0194743 0,07718525 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0194743 0,07701962 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0194743 0,07685469 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0194743 0,07669047 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0194743 0,07652695 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0194743 0,07636413 ! response to UV-B GO:0010224 5 5 0,000 0,0194743 0,076202 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0194743 0,07604055 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0194743 0,07587979 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0194743 0,07571971 ! interaction with symbiont GO:0051702 5 5 0,000 0,0194743 0,0755603 ! cellular extravasation GO:0045123 5 5 0,000 0,0194743 0,07540156 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0194743 0,07524348 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0194743 0,07508607 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0194743 0,07492931 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0194743 0,07477321 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0194743 0,07461776 ! response to amine stimulus GO:0014075 5 5 0,000 0,0194743 0,07446295 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0194743 0,07430878 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0194743 0,07415525 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0194743 0,07400235 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0194743 0,07385008 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0194743 0,07369844 ! neuron recognition GO:0008038 5 5 0,000 0,0194743 0,07354742 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,0194743 0,07339702 ! decidualization GO:0046697 5 5 0,000 0,0194743 0,07324723 ! hair follicle maturation GO:0048820 5 5 0,000 0,0194743 0,07309805 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0194743 0,07294947 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0194743 0,0728015 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0194743 0,07265413 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0194743 0,07250735 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0194743 0,07236117 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0194743 0,07221557 ! postreplication repair GO:0006301 5 5 0,000 0,0194743 0,07207056 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0194743 0,07192613 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0194743 0,07178228 ! histone methylation GO:0016571 5 5 0,000 0,0194743 0,071639 ! DNA methylation GO:0006306 5 5 0,000 0,0194743 0,0714963 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0194743 0,07135416 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0194743 0,07121258 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0194743 0,07107157 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0194743 0,07093111 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0194743 0,0707912 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0194743 0,07065185 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0194743 0,07051305 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0194743 0,07037479 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0194743 0,07023707 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0194743 0,07009988 ! sterol catabolic process GO:0016127 5 5 0,000 0,0194743 0,06996324 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0194743 0,06982712 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0194743 0,06969154 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0194743 0,06955647 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0194743 0,06942194 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0194743 0,06928792 ! zymogen activation GO:0031638 5 5 0,000 0,0194743 0,06915441 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0194743 0,06902142 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0194743 0,06888895 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0194743 0,06875697 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0194743 0,06862551 ! nucleosome positioning GO:0016584 5 5 0,000 0,0194743 0,06849454 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0194743 0,06836408 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0194743 0,06823411 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0194743 0,06810463 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0194743 0,06797565 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0194743 0,06784715 ! NADPH regeneration GO:0006740 5 5 0,000 0,0194743 0,06771913 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0194743 0,0675916 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0194743 0,06746455 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0194743 0,06733798 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0194743 0,06721187 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0194743 0,06708624 ! sarcomere organization GO:0045214 5 5 0,000 0,0194743 0,06696108 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0194743 0,06683639 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0194743 0,06671216 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0194743 0,06658839 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0194743 0,06646508 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0194743 0,06634222 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0194743 0,06621982 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0194743 0,06609787 ! spleen development GO:0048536 5 5 0,000 0,0194743 0,06597636 ! male genitalia development GO:0030539 5 5 0,000 0,0194743 0,0658553 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0194743 0,06573469 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0194743 0,06561452 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0194743 0,06549478 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0194743 0,06537548 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0194743 0,06525662 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0194743 0,06513819 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0194743 0,06502018 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0194743 0,06490261 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0194743 0,06478545 ! ATP catabolic process GO:0006200 5 5 0,000 0,0194743 0,06466872 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0194743 0,06455241 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0194743 0,06443652 ! blastocyst formation GO:0001825 5 5 0,000 0,0194743 0,06432104 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0194743 0,06420598 ! embryonic gut development GO:0048566 5 5 0,000 0,0194743 0,06409132 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0194743 0,06397708 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0194743 0,06386324 ! activation of innate immune response GO:0002218 5 5 0,000 0,0194743 0,06374981 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,0194743 0,06363677 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0194743 0,06352414 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0194743 0,06341191 ! muscle adaptation GO:0043500 5 5 0,000 0,0194743 0,06330007 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0194743 0,06318863 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0194743 0,06307758 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0194743 0,06296691 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0194743 0,06285664 ! defense response to fungus GO:0050832 5 5 0,000 0,0194743 0,06274675 ! lysogeny GO:0030069 5 5 0,000 0,0194743 0,06263724 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0194743 0,06252812 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0194743 0,06241938 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0194743 0,06231101 ! response to nicotine GO:0035094 5 5 0,000 0,0194743 0,06220302 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0194743 0,0620954 ! mitochondrion localization GO:0051646 5 5 0,000 0,0194743 0,06198815 ! nucleus localization GO:0051647 5 5 0,000 0,0194743 0,06188128 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0194743 0,06177477 ! reproductive developmental process GO:0003006 56 56 1,000 0,02005156 0,0634966 ! extracellular structure organization GO:0043062 56 56 1,000 0,02005156 0,06338769 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,0221183 0,0698014 ! protein localization in organelle GO:0033365 59 59 1,000 0,0221183 0,06968208 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,02282619 0,07178954 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02332509 0,07323365 ! axon extension GO:0048675 7 6 0,000 0,02332509 0,0731091 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02332509 0,07298497 ! tRNA modification GO:0006400 6 6 0,000 0,02332509 0,07286127 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02332509 0,07273799 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02332509 0,07261512 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02332509 0,07249266 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02332509 0,07237062 ! regulation of S phase GO:0033261 6 6 0,000 0,02332509 0,07224899 ! myotube differentiation GO:0014902 6 6 0,000 0,02332509 0,07212777 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02332509 0,07200695 ! bone remodeling GO:0046849 6 6 0,000 0,02332509 0,07188654 ! N-glycan processing GO:0006491 6 6 0,000 0,02332509 0,07176653 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02332509 0,07164692 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02332509 0,0715277 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02332509 0,07140889 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02332509 0,07129046 ! RNA methylation GO:0001510 6 6 0,000 0,02332509 0,07117243 ! cartilage condensation GO:0001502 7 6 0,000 0,02332509 0,07105479 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02332509 0,07093754 ! succinate metabolic process GO:0006105 7 6 0,000 0,02332509 0,07082068 ! artery development GO:0060840 6 6 0,000 0,02332509 0,07070419 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02332509 0,0705881 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02332509 0,07047238 ! androgen metabolic process GO:0008209 6 6 0,000 0,02332509 0,07035704 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02332509 0,07024208 ! limbic system development GO:0021761 7 6 0,000 0,02332509 0,07012749 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02332509 0,07001327 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02332509 0,06989943 ! pathogenesis GO:0009405 6 6 0,000 0,02332509 0,06978596 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02332509 0,06967285 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02332509 0,06956011 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02332509 0,06944774 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02332509 0,06933573 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02332509 0,06922407 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02332509 0,06911278 ! arginine metabolic process GO:0006525 6 6 0,000 0,02332509 0,06900185 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02332509 0,06889127 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02332509 0,06878104 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02332509 0,06867117 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02332509 0,06856164 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02332509 0,06845247 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02332509 0,06834364 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02332509 0,06823516 ! V(D)J recombination GO:0033151 6 6 0,000 0,02332509 0,06812702 ! focal adhesion formation GO:0048041 7 6 0,000 0,02332509 0,06801922 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02332509 0,06791177 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02332509 0,06780465 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02332509 0,06769787 ! regulation of heart rate GO:0002027 6 6 0,000 0,02332509 0,06759143 ! lipid digestion GO:0044241 6 6 0,000 0,02332509 0,06748532 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02332509 0,06737955 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02332509 0,0672741 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02332509 0,06716898 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02332509 0,0670642 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02332509 0,06695974 ! ruffle organization GO:0031529 6 6 0,000 0,02332509 0,0668556 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02332509 0,06675179 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02332509 0,06664829 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02332509 0,06654512 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02332509 0,06644227 ! L-amino acid transport GO:0015807 6 6 0,000 0,02332509 0,06633974 ! bone mineralization GO:0030282 6 6 0,000 0,02332509 0,06623752 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02332509 0,06613562 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02332509 0,06603402 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02332509 0,06593275 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02332509 0,06583178 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02332509 0,06573112 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02332509 0,06563076 ! regulation of organ growth GO:0046620 6 6 0,000 0,02332509 0,06553072 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02332509 0,06543097 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02332509 0,06533154 ! response to dsRNA GO:0043331 6 6 0,000 0,02332509 0,0652324 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02332509 0,06513356 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02332509 0,06503502 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02332509 0,06493678 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02332509 0,06483884 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02332509 0,06474119 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02332509 0,06464383 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02332509 0,06454677 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02332509 0,06445 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02332509 0,06435352 ! erythrocyte development GO:0048821 6 6 0,000 0,02332509 0,06425732 ! renal water homeostasis GO:0003091 6 6 0,000 0,02332509 0,06416142 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02332509 0,0640658 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02332509 0,06397046 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02332509 0,06387541 ! ribosome assembly GO:0042255 6 6 0,000 0,02332509 0,06378064 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02332509 0,06368615 ! diencephalon development GO:0021536 6 6 0,000 0,02332509 0,06359194 ! fucose catabolic process GO:0019317 6 6 0,000 0,02332509 0,06349801 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02332509 0,06340435 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02332509 0,06331097 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02332509 0,06321787 ! regulation of cell division GO:0051302 6 6 0,000 0,02332509 0,06312504 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02332509 0,06303248 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02332509 0,06294019 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02332509 0,06284817 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02332509 0,06275642 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02332509 0,06266494 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02332509 0,06257373 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02332509 0,06248278 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02332509 0,06239209 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02332509 0,06230167 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02332509 0,06221151 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02332509 0,0621216 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02332509 0,06203196 ! thymus development GO:0048538 6 6 0,000 0,02332509 0,06194258 ! lymph node development GO:0048535 6 6 0,000 0,02332509 0,06185345 ! organic cation transport GO:0015695 6 6 0,000 0,02332509 0,06176458 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02332509 0,06167597 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02332509 0,06158761 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02332509 0,0614995 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02332509 0,06141164 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02332509 0,06132404 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02332509 0,06123668 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02332509 0,06114957 ! alditol metabolic process GO:0019400 6 6 0,000 0,02332509 0,06106271 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02332509 0,0609761 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02332509 0,06088973 ! maternal placenta development GO:0001893 6 6 0,000 0,02332509 0,06080361 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02332509 0,06071773 ! axonogenesis GO:0007409 66 62 1,000 0,02426998 0,06308826 ! protein import GO:0017038 62 62 1,000 0,02426998 0,0629994 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02426998 0,06291079 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02575058 0,06665495 ! angiogenesis GO:0001525 65 64 1,000 0,02575058 0,06656146 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,02650449 0,06841426 ! respiratory burst GO:0045730 7 7 0,000 0,02716132 0,07001163 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02716132 0,06991385 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02716132 0,06981634 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02716132 0,0697191 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02716132 0,06962214 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02716132 0,06952544 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02716132 0,06942901 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02716132 0,06933285 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02716132 0,06923695 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02716132 0,06914132 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02716132 0,06904595 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02716132 0,06895085 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02716132 0,06885601 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02716132 0,06876142 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02716132 0,0686671 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02716132 0,06857304 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02716132 0,06847923 ! visual behavior GO:0007632 7 7 0,000 0,02716132 0,06838568 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02716132 0,06829238 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02716132 0,06819934 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02716132 0,06810655 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02716132 0,06801402 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02716132 0,06792173 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02716132 0,0678297 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02716132 0,06773791 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02716132 0,06764637 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02716132 0,06755508 ! digestive system development GO:0055123 7 7 0,000 0,02716132 0,06746404 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02716132 0,06737324 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02716132 0,06728268 ! protein targeting to ER GO:0045047 8 7 0,000 0,02716132 0,06719237 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02716132 0,0671023 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02716132 0,06701247 ! endoderm development GO:0007492 7 7 0,000 0,02716132 0,06692288 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02716132 0,06683353 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02716132 0,06674442 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02716132 0,06665555 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02716132 0,06656691 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02716132 0,06647851 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02716132 0,06639034 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02716132 0,06630241 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02716132 0,0662147 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02716132 0,06612723 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02716132 0,06603999 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02716132 0,06595299 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02716132 0,06586621 ! UV protection GO:0009650 7 7 0,000 0,02716132 0,06577965 ! DNA integration GO:0015074 7 7 0,000 0,02716132 0,06569333 ! myofibril assembly GO:0030239 7 7 0,000 0,02716132 0,06560723 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02716132 0,06552136 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02716132 0,06543571 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02716132 0,06535028 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02716132 0,06526508 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02716132 0,0651801 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02716132 0,06509534 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02716132 0,0650108 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02716132 0,06492648 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02716132 0,06484238 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02716132 0,06475849 ! axon cargo transport GO:0008088 7 7 0,000 0,02716132 0,06467483 ! eating behavior GO:0042755 7 7 0,000 0,02716132 0,06459138 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02716132 0,06450814 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02716132 0,06442512 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02716132 0,06434231 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02716132 0,06425971 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02716132 0,06417733 ! cranial nerve development GO:0021545 7 7 0,000 0,02716132 0,06409515 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02716132 0,06401319 ! induction of an organ GO:0001759 7 7 0,000 0,02716132 0,06393144 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02716132 0,06384989 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02716132 0,06376856 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02716132 0,06368742 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02716132 0,0636065 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02716132 0,06352578 ! platelet activation GO:0030168 8 7 0,000 0,02716132 0,06344527 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02716132 0,06336496 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02716132 0,06328485 ! natural killer cell activation GO:0030101 7 7 0,000 0,02716132 0,06320494 ! NADP metabolic process GO:0006739 7 7 0,000 0,02716132 0,06312524 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02716132 0,06304574 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02716132 0,06296644 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02716132 0,06288733 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02716132 0,06280843 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02716132 0,06272972 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02716132 0,06265121 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02716132 0,06257289 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02716132 0,06249478 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02716132 0,06241685 ! cell-cell recognition GO:0009988 8 7 0,000 0,02716132 0,06233912 ! hormone catabolic process GO:0042447 7 7 0,000 0,02716132 0,06226159 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02716132 0,06218424 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02716132 0,06210709 ! oxygen transport GO:0015671 7 7 0,000 0,02716132 0,06203013 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02716132 0,06195336 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02716132 0,06187678 ! regulation of axon extension GO:0030516 7 7 0,000 0,02716132 0,06180039 ! cell killing GO:0001906 7 7 0,000 0,02716132 0,06172419 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02716132 0,06164817 ! adult feeding behavior GO:0008343 7 7 0,000 0,02716132 0,06157234 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02716132 0,0614967 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02716132 0,06142125 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02716132 0,06134598 ! response to cold GO:0009409 7 7 0,000 0,02716132 0,06127089 ! DNA packaging GO:0006323 66 66 1,000 0,02726737 0,06143493 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,02726737 0,06135992 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02803915 0,0630197 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,02881975 0,06469524 ! response to nutrient levels GO:0031667 69 69 1,000 0,02960908 0,06638631 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02960908 0,06630564 ! cell part morphogenesis GO:0032990 75 70 1,000 0,03040709 0,06801003 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03098304 0,06921423 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03098304 0,06913043 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03098304 0,06904684 ! positive regulation of translation GO:0045727 8 8 0,000 0,03098304 0,06896345 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03098304 0,06888026 ! superoxide anion generation GO:0042554 8 8 0,000 0,03098304 0,06879727 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03098304 0,06871448 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03098304 0,06863189 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03098304 0,0685495 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03098304 0,06846731 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03098304 0,06838531 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03098304 0,06830351 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03098304 0,06822191 ! zinc ion transport GO:0006829 8 8 0,000 0,03098304 0,0681405 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03098304 0,06805928 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03098304 0,06797826 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03098304 0,06789743 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03098304 0,06781679 ! lipid localization GO:0010876 8 8 0,000 0,03098304 0,06773634 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03098304 0,06765609 ! response to cAMP GO:0051591 8 8 0,000 0,03098304 0,06757602 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03098304 0,06749614 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03098304 0,06741645 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03098304 0,06733695 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03098304 0,06725764 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03098304 0,06717851 ! sensory perception of taste GO:0050909 8 8 0,000 0,03098304 0,06709957 ! organelle fusion GO:0048284 8 8 0,000 0,03098304 0,06702082 ! pancreas development GO:0031016 8 8 0,000 0,03098304 0,06694225 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03098304 0,06686386 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03098304 0,06678566 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03098304 0,06670764 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03098304 0,0666298 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03098304 0,06655214 ! sperm motility GO:0030317 8 8 0,000 0,03098304 0,06647466 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03098304 0,06639737 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03098304 0,06632025 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03098304 0,06624331 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03098304 0,06616655 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03098304 0,06608997 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03098304 0,06601357 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03098304 0,06593734 ! Golgi organization GO:0007030 8 8 0,000 0,03098304 0,06586129 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03098304 0,06578541 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03098304 0,06570971 ! fructose metabolic process GO:0006000 8 8 0,000 0,03098304 0,06563418 ! mannose metabolic process GO:0006013 9 8 0,000 0,03098304 0,06555882 ! NAD metabolic process GO:0019674 8 8 0,000 0,03098304 0,06548364 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03098304 0,06540863 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03098304 0,06533379 ! response to fungus GO:0009620 8 8 0,000 0,03098304 0,06525913 ! stem cell differentiation GO:0048863 8 8 0,000 0,03098304 0,06518463 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03098304 0,0651103 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03098304 0,06503615 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03098304 0,06496216 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03098304 0,06488834 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03098304 0,06481468 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03098304 0,0647412 ! vasoconstriction GO:0042310 8 8 0,000 0,03098304 0,06466788 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03098304 0,06459472 ! muscle cell development GO:0055001 8 8 0,000 0,03098304 0,06452174 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03098304 0,06444891 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03098304 0,06437625 ! sensory perception of pain GO:0019233 8 8 0,000 0,03098304 0,06430376 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03098304 0,06423142 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03098304 0,06415925 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03098304 0,06408725 ! chromatin silencing GO:0006342 8 8 0,000 0,03098304 0,0640154 ! tissue regeneration GO:0042246 8 8 0,000 0,03098304 0,06394371 ! salivary gland development GO:0007431 8 8 0,000 0,03098304 0,06387219 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03098304 0,06380082 ! T cell homeostasis GO:0043029 8 8 0,000 0,03098304 0,06372962 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03098304 0,06365857 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03098304 0,06358768 ! water homeostasis GO:0030104 8 8 0,000 0,03098304 0,06351695 ! cofactor transport GO:0051181 8 8 0,000 0,03098304 0,06344637 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03098304 0,06337596 ! acid secretion GO:0046717 8 8 0,000 0,03098304 0,06330569 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03098304 0,06323559 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03098304 0,06316564 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03098304 0,06309584 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03098304 0,0630262 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03098304 0,06295671 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03098304 0,06288737 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03098304 0,06281819 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03098304 0,06274916 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03098304 0,06268028 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03098304 0,06261155 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03098304 0,06254297 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03098304 0,06247455 ! developmental induction GO:0031128 8 8 0,000 0,03098304 0,06240627 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03098304 0,06233814 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03098304 0,06227016 ! actin filament polymerization GO:0030041 9 8 0,000 0,03098304 0,06220233 ! peptide hormone processing GO:0016486 8 8 0,000 0,03098304 0,06213464 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03098304 0,0620671 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03098304 0,06199971 ! translational elongation GO:0006414 71 71 1,000 0,03121369 0,06239353 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,03121369 0,06232593 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 1,000 0,03121369 0,06225848 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03202881 0,06381524 ! lactation GO:0007595 10 9 0,000 0,03479029 0,06924245 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03479029 0,06916775 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03479029 0,06909322 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03479029 0,06901885 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03479029 0,06894463 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03479029 0,06887058 ! viral genome replication GO:0019079 9 9 0,000 0,03479029 0,06879668 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03479029 0,06872294 ! copper ion transport GO:0006825 9 9 0,000 0,03479029 0,06864937 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03479029 0,06857594 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03479029 0,06850268 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03479029 0,06842957 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03479029 0,06835662 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03479029 0,06828382 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03479029 0,06821118 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03479029 0,06813869 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03479029 0,06806636 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03479029 0,06799418 ! phospholipid efflux GO:0033700 9 9 0,000 0,03479029 0,06792215 ! response to alkaloid GO:0043279 10 9 0,000 0,03479029 0,06785027 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03479029 0,06777855 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03479029 0,06770698 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03479029 0,06763556 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03479029 0,06756429 ! response to ethanol GO:0045471 9 9 0,000 0,03479029 0,06749317 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03479029 0,06742219 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03479029 0,06735137 ! methionine metabolic process GO:0006555 9 9 0,000 0,03479029 0,0672807 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03479029 0,06721018 ! cerebral cortex development GO:0021987 9 9 0,000 0,03479029 0,0671398 ! response to osmotic stress GO:0006970 9 9 0,000 0,03479029 0,06706957 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03479029 0,06699949 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03479029 0,06692955 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03479029 0,06685976 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03479029 0,06679011 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03479029 0,06672061 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03479029 0,06665125 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03479029 0,06658204 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03479029 0,06651297 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03479029 0,06644405 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03479029 0,06637527 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03479029 0,06630663 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03479029 0,06623813 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03479029 0,06616977 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03479029 0,06610155 ! DNA replication initiation GO:0006270 9 9 0,000 0,03479029 0,06603348 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03479029 0,06596554 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03479029 0,06589775 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03479029 0,06583009 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03479029 0,06576257 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03479029 0,06569519 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03479029 0,06562795 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03479029 0,06556085 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03479029 0,06549388 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03479029 0,06542705 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03479029 0,06536035 ! collagen catabolic process GO:0030574 9 9 0,000 0,03479029 0,0652938 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03479029 0,06522737 ! purine base metabolic process GO:0006144 9 9 0,000 0,03479029 0,06516108 ! gas transport GO:0015669 9 9 0,000 0,03479029 0,06509493 ! cholesterol efflux GO:0033344 9 9 0,000 0,03479029 0,06502891 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03479029 0,06496303 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03479029 0,06489727 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03479029 0,06483166 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03479029 0,06476617 ! defense response to virus GO:0051607 9 9 0,000 0,03479029 0,06470081 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03479029 0,06463559 ! actin filament-based movement GO:0030048 9 9 0,000 0,03479029 0,0645705 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03479029 0,06450554 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,03622962 0,06710672 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,03622962 0,06703934 ! metal ion homeostasis GO:0055065 78 78 1,000 0,03709431 0,06857053 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03858314 0,07125123 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03858314 0,07117991 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03858314 0,07110873 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03858314 0,07103769 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03858314 0,07096679 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03858314 0,07089604 ! neuron maturation GO:0042551 10 10 0,000 0,03858314 0,07082543 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03858314 0,07075495 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03858314 0,07068462 GO:0045767|regulation of anti-apoptosis, ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03858314 0,07061443 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03858314 0,07054437 ! hormone secretion GO:0046879 10 10 0,000 0,03858314 0,07047446 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03858314 0,07040468 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03858314 0,07033504 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,03858314 0,07026554 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03858314 0,07019618 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03858314 0,07012695 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03858314 0,07005786 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03858314 0,0699889 ! glial cell development GO:0021782 10 10 0,000 0,03858314 0,06992009 ! phototransduction GO:0007602 11 10 0,000 0,03858314 0,0698514 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03858314 0,06978285 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03858314 0,06971444 ! fat cell differentiation GO:0045444 10 10 0,000 0,03858314 0,06964616 ! myoblast differentiation GO:0045445 10 10 0,000 0,03858314 0,06957801 ! centrosome cycle GO:0007098 10 10 0,000 0,03858314 0,06951 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03858314 0,06944212 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03858314 0,06937437 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03858314 0,06930675 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03858314 0,06923927 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03858314 0,06917191 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03858314 0,06910469 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03858314 0,0690376 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03858314 0,06897064 ! plasma membrane organization GO:0007009 10 10 0,000 0,03858314 0,06890381 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03858314 0,0688371 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,03858314 0,06877053 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03858314 0,06870408 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03858314 0,06863777 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03858314 0,06857158 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03858314 0,06850552 ! exocrine system development GO:0035272 10 10 0,000 0,03858314 0,06843958 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03858314 0,06837378 ! embryo implantation GO:0007566 11 10 0,000 0,03858314 0,0683081 ! regulation of protein binding GO:0043393 11 10 0,000 0,03858314 0,06824254 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03858314 0,06817711 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03858314 0,06811181 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03858314 0,06804663 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03858314 0,06798157 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03858314 0,06791664 ! cytolysis GO:0019835 10 10 0,000 0,03858314 0,06785184 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03858314 0,06778716 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03858314 0,0677226 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03858314 0,06765816 ! histone deacetylation GO:0016575 10 10 0,000 0,03858314 0,06759385 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03858314 0,06752966 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03858314 0,06746559 ! gland morphogenesis GO:0022612 10 10 0,000 0,03858314 0,06740164 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03858314 0,06733781 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03858314 0,0672741 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03858314 0,06721052 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03858314 0,06714705 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03858314 0,0670837 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03858314 0,06702048 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03858314 0,06695737 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03858314 0,06689438 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03858314 0,06683151 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03858314 0,06676876 ! nerve development GO:0021675 10 10 0,000 0,03858314 0,06670612 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03858314 0,06664361 ! gut development GO:0048565 10 10 0,000 0,03858314 0,06658121 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03858314 0,06651892 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03858314 0,06645675 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03858314 0,0663947 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03858314 0,06633277 ! neuron projection development GO:0031175 85 80 1,000 0,03884766 0,0667253 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,04153653 0,07127731 ! protein secretion GO:0009306 11 11 0,000 0,04236163 0,07262557 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04236163 0,07255808 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04236163 0,07249071 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04236163 0,07242346 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04236163 0,07235634 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04236163 0,07228934 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04236163 0,07222247 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04236163 0,07215572 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04236163 0,0720891 ! signal complex assembly GO:0007172 11 11 0,000 0,04236163 0,07202259 ! microtubule-based transport GO:0010970 11 11 0,000 0,04236163 0,07195621 ! endothelial cell migration GO:0043542 11 11 0,000 0,04236163 0,07188996 ! peroxisomal transport GO:0043574 11 11 0,000 0,04236163 0,07182382 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04236163 0,07175781 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04236163 0,07169191 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04236163 0,07162614 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04236163 0,07156049 ! T cell proliferation GO:0042098 11 11 0,000 0,04236163 0,07149496 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04236163 0,07142954 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04236163 0,07136425 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04236163 0,07129908 ! spinal cord development GO:0021510 11 11 0,000 0,04236163 0,07123403 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04236163 0,07116909 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04236163 0,07110427 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04236163 0,07103957 ! digestive system process GO:0022600 11 11 0,000 0,04236163 0,07097499 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04236163 0,07091053 ! fucose metabolic process GO:0006004 11 11 0,000 0,04236163 0,07084618 ! membrane budding GO:0006900 11 11 0,000 0,04236163 0,07078195 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04236163 0,07071784 ! monoamine transport GO:0015844 11 11 0,000 0,04236163 0,07065384 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04236163 0,07058996 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04236163 0,07052619 ! body fluid secretion GO:0007589 11 11 0,000 0,04236163 0,07046254 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04236163 0,070399 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04236163 0,07033558 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04236163 0,07027227 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04236163 0,07020908 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04236163 0,07014599 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04236163 0,07008303 ! oogenesis GO:0048477 11 11 0,000 0,04236163 0,07002017 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04236163 0,06995743 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04236163 0,0698948 ! vitamin transport GO:0051180 11 11 0,000 0,04236163 0,06983228 ! muscle maintenance GO:0046716 12 11 0,000 0,04236163 0,06976988 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04236163 0,06970758 ! hindbrain development GO:0030902 11 11 0,000 0,04236163 0,0696454 ! steroid catabolic process GO:0006706 11 11 0,000 0,04236163 0,06958333 ! endocrine process GO:0050886 11 11 0,000 0,04236163 0,06952136 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04236163 0,06945951 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04236163 0,06939777 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04236163 0,06933614 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,04336753 0,07091956 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04612583 0,07536338 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04612583 0,07529663 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04612583 0,07523 ! initiation of viral infection GO:0019059 12 12 0,000 0,04612583 0,07516348 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04612583 0,07509708 ! iron ion transport GO:0006826 13 12 0,000 0,04612583 0,0750308 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04612583 0,07496464 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04612583 0,07489859 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04612583 0,07483266 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04612583 0,07476684 ! collagen metabolic process GO:0032963 12 12 0,000 0,04612583 0,07470114 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04612583 0,07463556 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04612583 0,07457009 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04612583 0,07450473 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04612583 0,07443949 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04612583 0,07437436 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04612583 0,07430935 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,04612583 0,07424445 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04612583 0,07417967 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,04612583 0,07411499 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04612583 0,07405043 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04612583 0,07398599 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04612583 0,07392165 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04612583 0,07385743 ! acute-phase response GO:0006953 12 12 0,000 0,04612583 0,07379331 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04612583 0,07372931 ! vacuolar transport GO:0007034 12 12 0,000 0,04612583 0,07366542 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04612583 0,07360164 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04612583 0,07353797 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04612583 0,07347441 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04612583 0,07341097 ! male gonad development GO:0008584 12 12 0,000 0,04612583 0,07334763 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04612583 0,07328439 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04612583 0,07322127 ! renal system process GO:0003014 12 12 0,000 0,04612583 0,07315826 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04612583 0,07309536 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04612583 0,07303256 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04612583 0,07296987 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04612583 0,07290729 ! pallium development GO:0021543 13 12 0,000 0,04612583 0,07284481 ! cell fate determination GO:0001709 12 12 0,000 0,04612583 0,07278245 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04612583 0,07272019 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04612583 0,07265803 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04612583 0,07259598 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04612583 0,07253404 ! detection of light stimulus GO:0009583 13 12 0,000 0,04612583 0,07247221 ! synaptogenesis GO:0007416 12 12 0,000 0,04612583 0,07241048 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04612583 0,07234885 ! hormone transport GO:0009914 12 12 0,000 0,04612583 0,07228733 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04612583 0,07222591 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04612583 0,0721646 ! spermatid differentiation GO:0048515 13 12 0,000 0,04612583 0,07210339 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04612583 0,07204229 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04612583 0,07198129 ! neural tube closure GO:0001843 13 12 0,000 0,04612583 0,07192039 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04612583 0,07185959 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04612583 0,0717989 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,04711922 0,07328331 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,04903884 0,07620454 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04987577 0,0774398 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04987577 0,07737461 ! phenol metabolic process GO:0018958 13 13 0,000 0,04987577 0,07730954 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04987577 0,07724457 ! gluconeogenesis GO:0006094 13 13 0,000 0,04987577 0,07717972 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04987577 0,07711497 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04987577 0,07705033 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04987577 0,0769858 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04987577 0,07692137 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04987577 0,07685706 ! regeneration GO:0031099 13 13 0,000 0,04987577 0,07679285 ! keratinization GO:0031424 13 13 0,000 0,04987577 0,07672875 ! post-embryonic development GO:0009791 14 13 0,000 0,04987577 0,07666476 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04987577 0,07660087 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04987577 0,07653709 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04987577 0,07647341 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04987577 0,07640984 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04987577 0,07634638 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04987577 0,07628302 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04987577 0,07621977 ! autophagy GO:0006914 13 13 0,000 0,04987577 0,07615662 ! receptor metabolic process GO:0043112 14 13 0,000 0,04987577 0,07609358 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04987577 0,07603064 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04987577 0,0759678 ! ureteric bud development GO:0001657 13 13 0,000 0,04987577 0,07590507 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04987577 0,07584244 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04987577 0,07577992 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04987577 0,0757175 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04987577 0,07565518 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04987577 0,07559296 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04987577 0,07553085 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04987577 0,07546884 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04987577 0,07540692 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04987577 0,07534512 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04987577 0,07528341 ! vasodilation GO:0042311 14 13 0,000 0,04987577 0,0752218 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04987577 0,0751603 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04987577 0,07509889 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04987577 0,07503758 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,04987577 0,07497638 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04987577 0,07491527 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04987577 0,07485427 ! immunoglobulin production GO:0002377 13 13 0,000 0,04987577 0,07479336 GO:0002440|production of molecular mediator of immune response, ! cell-cell junction organization GO:0045216 13 13 0,000 0,04987577 0,07473255 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04987577 0,07467185 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04987577 0,07461123 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04987577 0,07455072 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04987577 0,07449031 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04987577 0,07442999 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04987577 0,07436977 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04987577 0,07430965 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04987577 0,07424963 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04987577 0,0741897 ! blastocyst development GO:0001824 13 13 0,000 0,04987577 0,07412987 ! telomere organization GO:0032200 13 13 0,000 0,04987577 0,07407014 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04987577 0,0740105 ! regulation of amine transport GO:0051952 13 13 0,000 0,04987577 0,07395096 ! tissue homeostasis GO:0001894 13 13 0,000 0,04987577 0,07389151 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04987577 0,07383216 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,05000936 0,07397051 ! regulation of response to stress GO:0080134 97 94 1,000 0,05197149 0,07681112 ! blood vessel development GO:0001568 95 94 1,000 0,05197149 0,07674957 ! neuron fate commitment GO:0048663 14 14 0,000 0,05361151 0,0791081 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05361151 0,07904481 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05361151 0,07898163 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05361151 0,07891854 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05361151 0,07885556 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05361151 0,07879268 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05361151 0,07872989 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05361151 0,07866721 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05361151 0,07860463 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05361151 0,07854214 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05361151 0,07847976 ! vesicle docking GO:0048278 14 14 0,000 0,05361151 0,07841747 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05361151 0,07835529 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05361151 0,0782932 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05361151 0,07823121 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05361151 0,07816932 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05361151 0,07810752 ! hair cycle GO:0042633 14 14 0,000 0,05361151 0,07804583 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05361151 0,07798423 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05361151 0,07792273 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05361151 0,07786132 ! lysosome organization GO:0007040 14 14 0,000 0,05361151 0,07780001 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05361151 0,0777388 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05361151 0,07767769 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05361151 0,07761667 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05361151 0,07755574 ! primary neural tube formation GO:0014020 15 14 0,000 0,05361151 0,07749492 ! peptide cross-linking GO:0018149 14 14 0,000 0,05361151 0,07743418 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05361151 0,07737355 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05361151 0,077313 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05361151 0,07725255 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05361151 0,0771922 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05361151 0,07713194 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05361151 0,07707178 ! collagen fibril organization GO:0030199 14 14 0,000 0,05361151 0,07701171 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05361151 0,07695173 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05361151 0,07689184 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05361151 0,07683205 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05361151 0,07677235 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05361151 0,07671275 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05361151 0,07665323 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05361151 0,07659381 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05361151 0,07653448 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05361151 0,07647525 ! vasculature development GO:0001944 97 96 1,000 0,0539613 0,07691468 ! blood circulation GO:0008015 99 98 1,000 0,05597828 0,07972795 GO:0003013|circulatory system process, ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05733311 0,08159453 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05733311 0,08153158 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05733311 0,08146871 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05733311 0,08140595 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05733311 0,08134328 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05733311 0,08128071 ! response to vitamin GO:0033273 15 15 0,000 0,05733311 0,08121823 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05733311 0,08115585 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05733311 0,08109357 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05733311 0,08103138 ! ovarian follicle development GO:0001541 15 15 0,000 0,05733311 0,08096929 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05733311 0,08090729 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05733311 0,08084539 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05733311 0,08078358 ! heme metabolic process GO:0042168 15 15 0,000 0,05733311 0,08072187 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05733311 0,08066025 ! chromosome condensation GO:0030261 15 15 0,000 0,05733311 0,08059872 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05733311 0,08053729 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05733311 0,08047595 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05733311 0,0804147 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05733311 0,08035355 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05733311 0,08029249 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05733311 0,08023153 ! phospholipid transport GO:0015914 15 15 0,000 0,05733311 0,08017065 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05733311 0,08010987 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05733311 0,08004918 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05733311 0,07998859 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05733311 0,07992808 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05733311 0,07986767 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05733311 0,07980734 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05733311 0,07974711 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05733311 0,07968697 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05733311 0,07962692 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05733311 0,07956696 ! response to hormone stimulus GO:0009725 102 100 1,000 0,05802191 0,08046228 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06104061 0,08458485 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06104061 0,0845213 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06104061 0,08445784 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06104061 0,08439449 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06104061 0,08433122 ! learning GO:0007612 16 16 0,000 0,06104061 0,08426805 ! circadian rhythm GO:0007623 16 16 0,000 0,06104061 0,08420498 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06104061 0,084142 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06104061 0,08407911 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,06104061 0,08401632 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06104061 0,08395362 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06104061 0,08389101 ! vesicle targeting GO:0006903 17 16 0,000 0,06104061 0,0838285 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06104061 0,08376608 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06104061 0,08370376 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06104061 0,08364152 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06104061 0,08357938 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06104061 0,08351733 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06104061 0,08345538 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06104061 0,08339351 ! cell fate specification GO:0001708 16 16 0,000 0,06104061 0,08333174 ! pentose metabolic process GO:0019321 16 16 0,000 0,06104061 0,08327006 ! fatty acid transport GO:0015908 16 16 0,000 0,06104061 0,08320847 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06104061 0,08314697 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06104061 0,08308556 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06104061 0,08302424 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06104061 0,08296302 ! polyol metabolic process GO:0019751 16 16 0,000 0,06104061 0,08290188 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06104061 0,08284083 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06104061 0,08277987 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06104061 0,08271901 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06104061 0,08265823 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06104061 0,08259754 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06104061 0,08253694 ! regulation of coagulation GO:0050818 17 16 0,000 0,06104061 0,08247643 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06473407 0,08740285 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06473407 0,08733887 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06473407 0,08727498 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06473407 0,08721118 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06473407 0,08714748 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06473407 0,08708386 ! sensory perception of smell GO:0007608 17 17 0,000 0,06473407 0,08702035 ! glucose transport GO:0015758 17 17 0,000 0,06473407 0,08695692 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06473407 0,08689359 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06473407 0,08683035 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06473407 0,0867672 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06473407 0,08670414 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06473407 0,08664117 ! neural crest cell development GO:0014032 19 17 0,000 0,06473407 0,0865783 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06473407 0,08651551 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06473407 0,08645282 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06473407 0,08639022 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06473407 0,08632771 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06473407 0,08626529 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06473407 0,08620296 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06473407 0,08614072 ! embryonic organ development GO:0048568 17 17 0,000 0,06473407 0,08607857 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06473407 0,08601651 ! liver development GO:0001889 17 17 0,000 0,06473407 0,08595454 ! gene silencing GO:0016458 17 17 0,000 0,06473407 0,08589265 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06841354 0,09070946 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06841354 0,09064425 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06841354 0,09057913 ! meiosis I GO:0007127 18 18 0,000 0,06841354 0,09051411 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06841354 0,09044918 ! membrane docking GO:0022406 18 18 0,000 0,06841354 0,09038434 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06841354 0,09031959 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06841354 0,09025494 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06841354 0,09019038 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06841354 0,09012591 ! hexose transport GO:0008645 18 18 0,000 0,06841354 0,09006154 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06841354 0,08999725 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06841354 0,08993306 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06841354 0,08986896 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,06841354 0,08980495 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06841354 0,08974103 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06841354 0,08967721 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06841354 0,08961347 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06841354 0,08954982 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06841354 0,08948627 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06841354 0,0894228 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06841354 0,08935943 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06841354 0,08929614 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07207906 0,09401395 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07207906 0,09394746 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07207906 0,09388107 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07207906 0,09381477 ! feeding behavior GO:0007631 19 19 0,000 0,07207906 0,09374856 ! peroxisome organization GO:0007031 19 19 0,000 0,07207906 0,09368245 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07207906 0,09361643 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07207906 0,0935505 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07207906 0,09348467 ! metanephros development GO:0001656 19 19 0,000 0,07207906 0,09341893 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07207906 0,09335328 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07207906 0,09328772 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07207906 0,09322226 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07207906 0,09315688 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07207906 0,0930916 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07207906 0,09302641 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07207906 0,09296131 ! eye morphogenesis GO:0048592 19 19 0,000 0,07207906 0,0928963 ! placenta development GO:0001890 19 19 0,000 0,07207906 0,09283139 ! response to heat GO:0009408 19 19 0,000 0,07207906 0,09276656 ! vesicle localization GO:0051648 20 19 0,000 0,07207906 0,09270182 ! regulation of muscle development GO:0048634 21 20 0,000 0,0757307 0,09733032 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,0757307 0,09726249 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0757307 0,09719476 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0757307 0,09712712 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0757307 0,09705958 ! neural tube development GO:0021915 21 20 0,000 0,0757307 0,09699213 ! nucleus organization GO:0006997 20 20 0,000 0,0757307 0,09692478 ! phagocytosis GO:0006909 21 20 0,000 0,0757307 0,09685751 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0757307 0,09679035 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0757307 0,09672327 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0757307 0,09665629 ! chromatin remodeling GO:0006338 20 20 0,000 0,0757307 0,0965894 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0757307 0,0965226 ! lipid oxidation GO:0034440 20 20 0,000 0,0757307 0,09645589 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0757307 0,09638928 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0757307 0,09632276 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0757307 0,09625633 ! RNA modification GO:0009451 20 20 0,000 0,0757307 0,09618999 ! single fertilization GO:0007338 21 20 0,000 0,0757307 0,09612374 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0757307 0,09605759 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,07936849 0,10060257 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07936849 0,10053342 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07936849 0,10046438 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07936849 0,10039542 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07936849 0,10032657 ! Notch signaling pathway GO:0007219 22 21 0,000 0,07936849 0,1002578 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07936849 0,10018913 ! ear morphogenesis GO:0042471 21 21 0,000 0,07936849 0,10012056 ! organic anion transport GO:0015711 21 21 0,000 0,07936849 0,10005207 ! cholesterol transport GO:0030301 21 21 0,000 0,07936849 0,09998369 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07936849 0,09991539 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07936849 0,09984719 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07936849 0,09977908 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07936849 0,09971107 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07936849 0,09964314 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07936849 0,09957531 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07936849 0,09950757 ! RNA export from nucleus GO:0006405 22 22 0,000 0,0829925 0,1039804 ! sister chromatid segregation GO:0000819 22 22 0,000 0,0829925 0,10390977 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,0829925 0,10383922 ! regulation of ion transport GO:0043269 22 22 0,000 0,0829925 0,10376878 ! odontogenesis GO:0042476 22 22 0,000 0,0829925 0,10369842 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,0829925 0,10362817 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,0829925 0,10355801 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,0829925 0,10348794 ! ovulation cycle process GO:0022602 22 22 0,000 0,0829925 0,10341797 ! spindle organization GO:0007051 22 22 0,000 0,0829925 0,10334809 ! cell chemotaxis GO:0060326 23 22 0,000 0,0829925 0,10327831 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,0829925 0,10320862 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,0829925 0,10313903 ! male sex differentiation GO:0046661 22 22 0,000 0,0829925 0,10306952 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,0829925 0,10300012 ! biopolymer methylation GO:0043414 22 22 0,000 0,0829925 0,1029308 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,0829925 0,10286158 ! detection of external stimulus GO:0009581 23 22 0,000 0,0829925 0,10279246 ! neuron migration GO:0001764 22 22 0,000 0,0829925 0,10272342 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,0829925 0,10265448 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,0829925 0,10258563 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,0829925 0,10251687 ! aerobic respiration GO:0009060 22 22 0,000 0,0829925 0,10244821 ! cytokine production GO:0001816 22 22 0,000 0,0829925 0,10237963 ! cytokinesis GO:0000910 23 22 0,000 0,0829925 0,10231115 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,0829925 0,10224276 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08660276 0,10661917 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08660276 0,10654799 ! viral infectious cycle GO:0019058 23 23 0,000 0,08660276 0,10647691 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08660276 0,10640593 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,08660276 0,10633504 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08660276 0,10626424 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08660276 0,10619354 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08660276 0,10612293 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08660276 0,10605242 ! endocrine system development GO:0035270 23 23 0,000 0,08660276 0,105982 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,08660276 0,10591167 ! female gonad development GO:0008585 23 23 0,000 0,08660276 0,10584144 ! lipid homeostasis GO:0055088 23 23 0,000 0,08660276 0,1057713 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08660276 0,10570125 ! cell projection assembly GO:0030031 25 23 0,000 0,08660276 0,1056313 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09019934 0,10994536 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09019934 0,10987269 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,09019934 0,10980012 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,09019934 0,10972765 ! ovulation cycle GO:0042698 24 24 0,000 0,09019934 0,10965527 ! fertilization GO:0009566 25 24 0,000 0,09019934 0,10958298 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09019934 0,10951079 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,09019934 0,1094387 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09019934 0,1093667 ! glucan metabolic process GO:0044042 25 24 0,000 0,09019934 0,1092948 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09378228 0,11356159 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09378228 0,11348702 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09378228 0,11341256 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09378228 0,11333819 ! cellular component disassembly GO:0022411 26 25 0,000 0,09378228 0,11326392 ! endosome transport GO:0016197 25 25 0,000 0,09378228 0,11318974 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09378228 0,11311567 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,09378228 0,11304169 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09378228 0,1129678 ! excretion GO:0007588 25 25 0,000 0,09378228 0,11289402 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09378228 0,11282033 ! gastrulation GO:0007369 25 25 0,000 0,09378228 0,11274673 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09378228 0,11267323 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,09378228 0,11259983 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09378228 0,11252652 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09735163 0,11673328 ! glycolysis GO:0006096 26 26 0,000 0,09735163 0,11665738 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09735163 0,11658158 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09735163 0,11650587 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09735163 0,11643027 ! cellular defense response GO:0006968 26 26 0,000 0,09735163 0,11635476 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09735163 0,11627936 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09735163 0,11620405 ! germ cell development GO:0007281 27 26 0,000 0,09735163 0,11612883 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09735163 0,11605372 GO:0035150|regulation of tube size, ! chloride transport GO:0006821 27 27 0,000 0,10090743 0,12021487 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,10090743 0,12013721 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,10090743 0,12005965 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,10090743 0,11998219 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,10090743 0,11990484 ! peptide metabolic process GO:0006518 29 27 0,000 0,10090743 0,11982758 ! mesenchymal cell development GO:0014031 29 27 0,000 0,10090743 0,11975042 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,10090743 0,11967336 ! defense response to bacterium GO:0042742 27 27 0,000 0,10090743 0,1195964 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,10090743 0,11951954 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,10090743 0,11944277 ! cell growth GO:0016049 27 27 0,000 0,10090743 0,11936611 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10444975 0,12347716 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,10444975 0,12339801 ! carbohydrate transport GO:0008643 28 28 0,000 0,10444975 0,12331896 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10444975 0,12324001 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10444975 0,12316116 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10444975 0,12308241 ! developmental growth GO:0048589 28 28 0,000 0,10444975 0,12300376 ! cartilage development GO:0051216 29 28 0,000 0,10444975 0,12292522 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10797863 0,1269972 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10797863 0,1269162 ! leukocyte migration GO:0050900 30 29 0,000 0,10797863 0,12683531 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10797863 0,12675453 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10797863 0,12667384 ! tRNA processing GO:0008033 29 29 0,000 0,10797863 0,12659326 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10797863 0,12651278 ! adult behavior GO:0030534 30 29 0,000 0,10797863 0,12643241 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10797863 0,12635213 ! transition metal ion transport GO:0000041 31 30 0,000 0,11149411 0,13038302 ! RNA catabolic process GO:0006401 30 30 0,000 0,11149411 0,13030034 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,11149411 0,13021777 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,11149411 0,1301353 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,11149411 0,13005294 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,11149411 0,12997068 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,11149411 0,12988852 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,11149411 0,12980647 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,11149411 0,12972452 ! response to temperature stimulus GO:0009266 30 30 0,000 0,11149411 0,12964268 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,11149411 0,12956094 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,11149411 0,1294793 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,11149411 0,12939776 ! vesicle organization GO:0016050 30 30 0,000 0,11149411 0,12931633 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,11149411 0,129235 ! establishment of organelle localization GO:0051656 31 30 0,000 0,11149411 0,12915377 ! membrane fusion GO:0006944 31 31 0,000 0,11499625 0,13312694 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11499625 0,13304337 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,11499625 0,1329599 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11499625 0,13287654 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11499625 0,13279329 ! digestion GO:0007586 31 31 0,000 0,11499625 0,13271014 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11499625 0,13262709 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11499625 0,13254415 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11499625 0,13246131 ! camera-type eye development GO:0043010 31 31 0,000 0,11499625 0,13237857 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11499625 0,13229594 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11499625 0,1322134 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11499625 0,13213098 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11848509 0,13605485 ! glucose catabolic process GO:0006007 32 32 0,000 0,11848509 0,13597013 ! lipid modification GO:0030258 32 32 0,000 0,11848509 0,13588552 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11848509 0,13580101 ! cell maturation GO:0048469 32 32 0,000 0,11848509 0,13571661 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11848509 0,13563232 ! kidney development GO:0001822 32 32 0,000 0,11848509 0,13554813 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11848509 0,13546404 ! amino acid transport GO:0006865 33 33 0,000 0,12196069 0,13935125 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,12196069 0,13926491 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,12196069 0,13917867 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,12196069 0,13909255 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,12196069 0,13900653 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,12196069 0,13892062 ! regulation of actin filament length GO:0030832 34 34 0,000 0,1254231 0,14277626 ! response to metal ion GO:0010038 34 34 0,000 0,1254231 0,14268813 ! ear development GO:0043583 34 34 0,000 0,1254231 0,1426001 ! muscle cell differentiation GO:0042692 35 34 0,000 0,1254231 0,14251219 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,1254231 0,14242438 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,1254231 0,14233668 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1254231 0,14224909 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,1254231 0,1421616 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,1254231 0,14207423 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1254231 0,14198696 ! detection of stimulus GO:0051606 36 34 0,000 0,1254231 0,14189979 ! acute inflammatory response GO:0002526 35 35 0,000 0,12887235 0,14571272 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12887235 0,14562338 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12887235 0,14553415 ! mesoderm development GO:0007498 35 35 0,000 0,12887235 0,14544503 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,12887235 0,14535602 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,12887235 0,14526712 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,12887235 0,14517832 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12887235 0,14508964 ! hydrogen transport GO:0006818 36 36 0,000 0,1323085 0,14886725 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1323085 0,14877642 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1323085 0,14868571 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1323085 0,1485951 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1323085 0,1485046 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,1323085 0,14841422 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1323085 0,14832394 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1323085 0,14823377 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1323085 0,14814372 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1323085 0,14805377 ! gonad development GO:0008406 36 36 0,000 0,1323085 0,14796393 ! activation of immune response GO:0002253 36 36 0,000 0,1323085 0,1478742 ! coagulation GO:0050817 39 36 0,000 0,1323085 0,14778458 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,13573159 0,15151625 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,13573159 0,15142453 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,13573159 0,15133293 ! eye development GO:0001654 37 37 0,000 0,13573159 0,15124143 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13573159 0,15115005 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13573159 0,15105877 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,13573159 0,15096761 ! positive regulation of secretion GO:0051047 39 38 0,000 0,13914168 0,15466714 ! neurotransmitter transport GO:0006836 40 38 0,000 0,13914168 0,15457391 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,13914168 0,1544808 ! exocytosis GO:0006887 40 38 0,000 0,13914168 0,15438779 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,13914168 0,1542949 ! chromosome segregation GO:0007059 38 38 0,000 0,13914168 0,15420212 ! urogenital system development GO:0001655 38 38 0,000 0,13914168 0,15410945 ! hexose catabolic process GO:0019320 38 38 0,000 0,13914168 0,15401689 ! RNA elongation GO:0006354 38 38 0,000 0,13914168 0,15392444 ! meiotic cell cycle GO:0051321 38 38 0,000 0,13914168 0,15383211 ! regulation of neurological system process GO:0031644 38 38 0,000 0,13914168 0,15373988 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,14253881 0,15739906 ! hemostasis GO:0007599 42 39 0,000 0,14253881 0,15730481 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,14253881 0,15721067 ! response to unfolded protein GO:0006986 39 39 0,000 0,14253881 0,15711665 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,14253881 0,15702274 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,14253881 0,15692893 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,14253881 0,15683525 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,14253881 0,15674167 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,14253881 0,1566482 ! developmental maturation GO:0021700 39 39 0,000 0,14253881 0,15655485 ! limb development GO:0060173 39 39 0,000 0,14253881 0,15646161 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,14592304 0,16008104 ! DNA catabolic process GO:0006308 41 40 0,000 0,14592304 0,15998581 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14592304 0,1598907 ! organelle localization GO:0051640 41 40 0,000 0,14592304 0,15979569 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,14929439 0,16339048 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,14929439 0,16329351 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14929439 0,16319666 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14929439 0,16309992 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,14929439 0,1630033 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14929439 0,16290679 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14929439 0,16281039 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,15265293 0,16637454 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,15265293 0,16627621 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,15265293 0,166178 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,15265293 0,1660799 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,15265293 0,16598192 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,15265293 0,16588405 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,15265293 0,1657863 ! forebrain development GO:0030900 43 42 0,000 0,15265293 0,16568866 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,15265293 0,16559114 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,15265293 0,16549374 ! reproductive structure development GO:0048608 43 43 0,000 0,1559987 0,16902152 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1559987 0,16892221 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1559987 0,16882302 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1559987 0,16872395 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,1559987 0,16862499 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15933175 0,17212685 ! mRNA transport GO:0051028 44 44 0,000 0,15933175 0,17202602 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15933175 0,1719253 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15933175 0,1718247 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15933175 0,17172422 ! amine biosynthetic process GO:0009309 46 45 0,000 0,16265212 0,17520038 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,16265212 0,17509804 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,16265212 0,17499583 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,16265212 0,17489373 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,16265212 0,17479175 ! protein processing GO:0016485 45 45 0,000 0,16265212 0,17468989 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16595985 0,17813862 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16595985 0,17803493 ! tube morphogenesis GO:0035239 47 46 0,000 0,16595985 0,17793136 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16595985 0,17782791 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16595985 0,17772459 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16595985 0,17762138 ! regulation of blood pressure GO:0008217 48 47 0,000 0,16925501 0,18104294 ! sex differentiation GO:0007548 47 47 0,000 0,16925501 0,18093792 ! amine transport GO:0015837 47 47 0,000 0,16925501 0,18083303 ! rhythmic process GO:0048511 47 47 0,000 0,16925501 0,18072826 ! calcium ion transport GO:0006816 48 48 0,000 0,17253762 0,18412672 ! actin filament organization GO:0007015 50 48 0,000 0,17253762 0,18402016 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,17253762 0,18391373 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,17253762 0,18380742 ! DNA recombination GO:0006310 48 48 0,000 0,17253762 0,18370124 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,17580775 0,18707487 ! divalent metal ion transport GO:0070838 49 49 0,000 0,17580775 0,18696692 ! response to nutrient GO:0007584 49 49 0,000 0,17580775 0,1868591 ! response to bacterium GO:0009617 50 49 0,000 0,17580775 0,1867514 ! regulation of ligase activity GO:0051340 50 49 0,000 0,17580775 0,18664382 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,17580775 0,18653637 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,17580775 0,18642904 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,17906542 0,18977434 ! RNA transport GO:0050658 50 50 0,000 0,17906542 0,18966527 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,17906542 0,18955633 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17906542 0,18944752 ! transcription initiation GO:0006352 50 50 0,000 0,17906542 0,18933883 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,17906542 0,18923026 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,1823107 0,19254935 ! positive regulation of immune response GO:0050778 51 51 0,000 0,1823107 0,19243907 ! rRNA metabolic process GO:0016072 51 51 0,000 0,1823107 0,19232892 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,1823107 0,19221889 ! RNA localization GO:0006403 52 52 0,000 0,18554362 0,19551566 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,18554362 0,19540394 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,18554362 0,19529234 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,18554362 0,19518087 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,18554362 0,19506953 ! sodium ion transport GO:0006814 53 53 0,000 0,18876423 0,19834235 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18876423 0,19822933 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18876423 0,19811644 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18876423 0,19800369 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18876423 0,19789106 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,19197257 0,20114011 ! response to virus GO:0009615 54 54 0,000 0,19197257 0,20102583 ! hormone metabolic process GO:0042445 55 54 0,000 0,19197257 0,20091167 ! sulfur metabolic process GO:0006790 55 54 0,000 0,19197257 0,20079765 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,1951687 0,20402491 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,1951687 0,20390925 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,19835265 0,20711837 ! ATP metabolic process GO:0046034 57 57 0,000 0,20152446 0,2103112 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,20152446 0,21019218 ! innate immune response GO:0045087 58 58 0,000 0,20468419 0,21336706 ! dephosphorylation GO:0016311 60 59 0,000 0,20783188 0,21652581 ! carboxylic acid transport GO:0046942 59 59 0,000 0,20783188 0,21640348 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,20783188 0,21628129 ! immune effector process GO:0002252 59 59 0,000 0,20783188 0,21615923 ! potassium ion transport GO:0006813 60 60 0,000 0,21096757 0,2192968 ! protein polymerization GO:0051258 65 60 0,000 0,21096757 0,21917319 ! cellular respiration GO:0045333 62 61 0,000 0,21409131 0,22229311 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,21409131 0,22216795 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,21409131 0,22204292 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,21409131 0,22191804 ! lipid transport GO:0006869 62 62 0,000 0,21720313 0,22501707 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21720313 0,22489066 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,21720313 0,22476439 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,21720313 0,22463826 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21720313 0,22451227 ! regulation of secretion GO:0051046 65 63 0,000 0,22030309 0,2275889 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,22030309 0,2274614 ! glucose metabolic process GO:0006006 63 63 0,000 0,22030309 0,22733404 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,22030309 0,22720682 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,22030309 0,22707975 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,22339122 0,23013417 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,22339122 0,2300056 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,22339122 0,22987718 ! anion transport GO:0006820 65 65 0,000 0,22646758 0,23291281 ! regulation of hormone levels GO:0010817 66 65 0,000 0,22646758 0,23278291 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,2295322 0,23580147 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,2295322 0,23567011 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,2295322 0,23553889 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,23258512 0,23853889 ! muscle contraction GO:0006936 67 67 0,000 0,23258512 0,23840622 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,23258512 0,2382737 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,2356264 0,24125525 ! sensory perception of sound GO:0007605 71 69 0,000 0,23865606 0,24422161 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,24167416 0,24717286 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,24167416 0,24703577 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,24468074 0,2499704 ! ribosome biogenesis GO:0042254 71 71 0,000 0,24468074 0,24983192 ! secretion by cell GO:0032940 75 72 0,000 0,24767584 0,25275004 ! muscle system process GO:0003012 72 72 0,000 0,24767584 0,25261017 ! sensory organ development GO:0007423 72 72 0,000 0,24767584 0,25247045 ! regulation of cytokine production GO:0001817 72 72 0,000 0,24767584 0,25233089 ! electron transport chain GO:0022900 75 74 0,000 0,25363176 0,25825599 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,25363176 0,25811338 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,25659267 0,2609825 ! response to oxidative stress GO:0006979 76 75 0,000 0,25659267 0,26083855 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,25659267 0,26069476 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,25954227 0,26354622 ! microtubule-based movement GO:0007018 82 78 0,000 0,26540769 0,26935373 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,26540769 0,26920548 ! regulation of immune response GO:0050776 78 78 0,000 0,26540769 0,26905741 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,27122835 0,27480695 ! lipid catabolic process GO:0016042 82 81 0,000 0,274122 0,27758618 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27987615 0,28325741 ! ncRNA processing GO:0034470 83 83 0,000 0,27987615 0,28310195 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,28273673 0,28583861 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,28558636 0,28856122 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,28558636 0,2884031 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,28842509 0,29111032 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,28842509 0,29095098 ! male gamete generation GO:0048232 90 88 0,000 0,29407 0,29648305 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,29407 0,29632095 ! chemotaxis GO:0006935 90 89 0,000 0,29687626 0,29898522 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,29967177 0,30163576 ! brain development GO:0007420 91 90 0,000 0,29967177 0,30147111 ! DNA replication GO:0006260 91 91 0,000 0,30245658 0,30410665 ! visual perception GO:0007601 93 92 0,000 0,30523073 0,30672859 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,30523073 0,30656144 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,30523073 0,30639446 ! tissue morphogenesis GO:0048729 94 93 0,000 0,30799425 0,30900022 ! cofactor metabolic process GO:0051186 95 94 0,000 0,31074718 0,31159252 ! endocytosis GO:0006897 99 98 0,000 0,32165382 0,32235345 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,32165382 0,32217826 ! regulation of system process GO:0044057 98 98 0,000 0,32165382 0,32200326 ! anti-apoptosis GO:0006916 100 99 0,000 0,32435441 0,32453049 ! response to other organism GO:0051707 101 100 0,000 0,32704463 0,32704463