pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6202-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of translation GO:0006417 151 100 8,000 1,477E-10 3,396E-07 ! regulation of translational initiation GO:0006446 64 45 5,000 1,826E-08 2,1E-05 ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 1,368E-06 1,049E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 1,465E-05 8,423E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 1,623E-05 7,466E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 4,000 1,839E-05 7,049E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,9E-05 6,244E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 2,608E-05 7,498E-03 ! response to UV GO:0009411 75 46 3,000 2,848E-05 7,279E-03 ! regulation of DNA replication GO:0006275 75 48 3,000 3,377E-05 7,767E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 3,521E-05 7,362E-03 ! positive regulation of DNA replication GO:0045740 29 18 2,000 4,213E-05 8,076E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 4,213E-05 7,454E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 4,3E-05 7,063E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 4,3E-05 6,593E-03 ! aging GO:0007568 79 52 3,000 4,644E-05 6,676E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 4,99E-05 6,751E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 4,99E-05 6,376E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,854E-05 7,087E-03 ! positive regulation of cell motion GO:0051272 99 56 3,000 6,229E-05 7,163E-03 ! cell aging GO:0007569 32 21 2,000 6,811E-05 7,46E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 6,811E-05 7,121E-03 ! protein tetramerization GO:0051262 39 22 2,000 7,865E-05 7,865E-03 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 9,02E-05 8,644E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 9,02E-05 8,298E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 9,02E-05 7,979E-03 ! regulation of caspase activity GO:0043281 97 65 3,000 1,119E-04 9,531E-03 ! protein oligomerization GO:0051259 100 65 3,000 1,119E-04 9,191E-03 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 1,259E-04 9,988E-03 ! translational initiation GO:0006413 43 26 2,000 1,313E-04 0,01006901 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,436E-04 0,01065601 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,436E-04 0,01032301 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 1,000 1,436E-04 0,01001019 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 1,436E-04 9,716E-03 ! protein maturation by protein folding GO:0022417 12 5 1,000 1,436E-04 9,438E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,436E-04 9,176E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 1,000 1,436E-04 8,928E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,436E-04 8,693E-03 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 1,436E-04 8,47E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,436E-04 8,258E-03 ! regulation of peptidase activity GO:0052547 106 72 3,000 1,666E-04 9,348E-03 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 1,831E-04 0,01002497 ! regulation of helicase activity GO:0051095 11 6 1,000 2,149E-04 0,01149481 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 2,149E-04 0,01123357 ! mRNA stabilization GO:0048255 15 6 1,000 2,149E-04 0,01098393 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 1,000 2,149E-04 0,01074515 GO:0031958|corticosteroid receptor signaling pathway, ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 2,149E-04 0,01051653 ! ER overload response GO:0006983 7 6 1,000 2,149E-04 0,01029744 ! male sex determination GO:0030238 9 6 1,000 2,149E-04 0,01008728 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 2,149E-04 9,886E-03 ! regulation of meiosis GO:0040020 10 6 1,000 2,149E-04 9,692E-03 GO:0051445|regulation of meiotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 2,149E-04 9,505E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 2,149E-04 9,326E-03 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 2,704E-04 0,01151558 ! negative regulation of hydrolase activity GO:0051346 50 33 2,000 2,704E-04 0,0113062 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,001E-04 0,01232632 ! T-helper 1 type immune response GO:0042088 11 7 1,000 3,001E-04 0,01211007 ! behavioral fear response GO:0001662 13 7 1,000 3,001E-04 0,01190128 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 10 7 1,000 3,001E-04 0,01169956 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 3,001E-04 0,01150457 ! B cell lineage commitment GO:0002326 17 7 1,000 3,001E-04 0,01131597 ! T cell lineage commitment GO:0002360 12 7 1,000 3,001E-04 0,01113345 ! response to tumor cell GO:0002347 12 7 1,000 3,001E-04 0,01095673 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 3,159E-04 0,01135388 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 3,226E-04 0,01141361 ! cell cycle arrest GO:0007050 150 86 3,000 3,304E-04 0,0115138 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 3,304E-04 0,01134195 ! interphase GO:0051325 159 88 3,000 3,607E-04 0,0122013 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 3,992E-04 0,01330561 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 3,992E-04 0,01311553 ! induction of positive chemotaxis GO:0050930 14 8 1,000 3,992E-04 0,0129308 ! keratinocyte proliferation GO:0043616 12 8 1,000 3,992E-04 0,01275121 ! pseudouridine synthesis GO:0001522 9 8 1,000 3,992E-04 0,01257653 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,992E-04 0,01240658 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,992E-04 0,01224116 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 3,992E-04 0,01208009 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 3,992E-04 0,01192321 ! regulation of embryonic development GO:0045995 16 8 1,000 3,992E-04 0,01177034 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 3,992E-04 0,01162135 ! B cell differentiation GO:0030183 62 40 2,000 4,803E-04 0,01380864 ! response to light stimulus GO:0009416 153 96 3,000 5,022E-04 0,01426103 ! regulation of developmental growth GO:0048638 13 9 1,000 5,119E-04 0,01435946 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 5,119E-04 0,01418646 ! regulation of glycolysis GO:0006110 15 9 1,000 5,119E-04 0,01401757 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 5,119E-04 0,01385266 ! lung alveolus development GO:0048286 17 9 1,000 5,119E-04 0,01369158 ! motor axon guidance GO:0008045 14 9 1,000 5,119E-04 0,01353421 ! positive regulation of phagocytosis GO:0050766 11 9 1,000 5,119E-04 0,01338041 ! sequestering of metal ion GO:0051238 11 9 1,000 5,119E-04 0,01323007 ! localization within membrane GO:0051668 15 9 1,000 5,119E-04 0,01308307 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 5,55E-04 0,01402841 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 5,95E-04 0,01487589 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 5,95E-04 0,01471593 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 6,368E-04 0,01558203 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 6,383E-04 0,01545477 ! regulation of B cell proliferation GO:0030888 15 10 1,000 6,383E-04 0,01529378 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 6,383E-04 0,01513611 ! blood vessel remodeling GO:0001974 21 10 1,000 6,383E-04 0,01498166 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 6,383E-04 0,01483033 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 6,383E-04 0,01468203 ! response to X-ray GO:0010165 16 10 1,000 6,383E-04 0,01453666 ! fear response GO:0042596 16 10 1,000 6,383E-04 0,01439415 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 6,383E-04 0,0142544 ! regulation of bone resorption GO:0045124 24 10 1,000 6,383E-04 0,01411734 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 6,383E-04 0,01398289 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 6,383E-04 0,01385097 GO:0043470|regulation of carbohydrate catabolic process, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 6,383E-04 0,01372152 ! positive regulation of cell cycle GO:0045787 77 45 2,000 6,805E-04 0,01449119 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 7,733E-04 0,0163178 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cortical cytoskeleton organization GO:0030865 20 11 1,000 7,783E-04 0,01627301 ! virus-host interaction GO:0019048 17 11 1,000 7,783E-04 0,01612641 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 7,783E-04 0,01598242 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 7,783E-04 0,01584099 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 7,783E-04 0,01570203 ! regulation of intracellular pH GO:0051453 17 11 1,000 7,783E-04 0,01556549 ! regulation of phagocytosis GO:0050764 14 11 1,000 7,783E-04 0,0154313 ! regulation of leukocyte migration GO:0002685 24 11 1,000 7,783E-04 0,01529941 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 7,783E-04 0,01516976 GO:0042130|negative regulation of T cell proliferation, ! regulation of intracellular transport GO:0032386 78 49 2,000 8,739E-04 0,01689019 ! maintenance of location GO:0051235 84 49 2,000 8,739E-04 0,01674944 ! positive regulation of growth GO:0045927 67 50 2,000 9,271E-04 0,01762308 ! tRNA modification GO:0006400 14 12 1,000 9,316E-04 0,01756332 ! positive regulation of cell growth GO:0030307 16 12 1,000 9,316E-04 0,01742053 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 9,316E-04 0,01728004 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 9,316E-04 0,0171418 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 9,316E-04 0,01700576 ! histone acetylation GO:0016573 23 12 1,000 9,316E-04 0,01687185 ! peptidyl-lysine modification GO:0018205 18 12 1,000 9,316E-04 0,01674004 ! response to gamma radiation GO:0010332 20 12 1,000 9,316E-04 0,01661027 ! regulation of mRNA stability GO:0043488 27 12 1,000 9,316E-04 0,0164825 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 9,316E-04 0,01635668 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,098E-03 0,01913675 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 1,098E-03 0,01899287 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,098E-03 0,01885113 ! regulation of cellular pH GO:0030641 20 13 1,000 1,098E-03 0,01871149 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,098E-03 0,01857391 ! regulation of RNA stability GO:0043487 28 13 1,000 1,098E-03 0,01843833 ! regulation of bone remodeling GO:0046850 90 53 2,000 1,099E-03 0,01831773 ! regulation of tissue remodeling GO:0034103 91 54 2,000 1,161E-03 0,01920321 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 1,278E-03 0,0209984 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,278E-03 0,02084947 ! heterophilic cell adhesion GO:0007157 29 14 1,000 1,278E-03 0,02070264 ! cellular response to starvation GO:0009267 21 14 1,000 1,278E-03 0,02055787 ! negative regulation of caspase activity GO:0043154 20 14 1,000 1,278E-03 0,02041511 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,278E-03 0,02027431 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,278E-03 0,02013545 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 1,278E-03 0,01999847 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 1,29E-03 0,02004598 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,358E-03 0,02096035 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,428E-03 0,02189645 ! positive regulation of cell size GO:0045793 20 15 1,000 1,471E-03 0,02240839 ! skin development GO:0043588 25 15 1,000 1,471E-03 0,02226097 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 1,471E-03 0,02211547 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,471E-03 0,02197186 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,471E-03 0,02183011 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 1,471E-03 0,02169017 ! activation of MAPK activity GO:0000187 84 59 2,000 1,5E-03 0,02198084 ! lung development GO:0030324 94 59 2,000 1,5E-03 0,02184172 ! regulation of homeostatic process GO:0032844 105 60 2,000 1,575E-03 0,02278444 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,652E-03 0,02374832 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,677E-03 0,02395959 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,677E-03 0,0238117 ! protein export from nucleus GO:0006611 24 16 1,000 1,677E-03 0,02366561 ! G1 phase GO:0051318 27 16 1,000 1,677E-03 0,02352131 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,677E-03 0,02337876 ! negative regulation of translation GO:0017148 22 16 1,000 1,677E-03 0,02323792 ! negative regulation of cell growth GO:0030308 106 62 2,000 1,731E-03 0,02384469 ! respiratory tube development GO:0030323 99 62 2,000 1,731E-03 0,02370275 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 1,896E-03 0,02580491 ! memory GO:0007613 25 17 1,000 1,896E-03 0,02565312 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 1,896E-03 0,0255031 ! cell-substrate junction assembly GO:0007044 39 17 1,000 1,896E-03 0,02535483 ! neuromuscular junction development GO:0007528 23 17 1,000 1,896E-03 0,02520827 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 1,896E-03 0,02506339 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,896E-03 0,02492017 ! negative regulation of cell size GO:0045792 108 64 2,000 1,897E-03 0,02478943 ! respiratory system development GO:0060541 100 64 2,000 1,897E-03 0,02464938 ! B cell activation GO:0042113 104 65 2,000 1,983E-03 0,02562695 ! axis specification GO:0009798 26 18 1,000 2,128E-03 0,02734104 ! somitogenesis GO:0001756 24 18 1,000 2,128E-03 0,02718914 ! cellular response to nutrient levels GO:0031669 27 18 1,000 2,128E-03 0,02703893 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 2,128E-03 0,02689036 ! activation of JUN kinase activity GO:0007257 23 18 1,000 2,128E-03 0,02674342 ! negative regulation of T cell activation GO:0050868 25 18 1,000 2,128E-03 0,02659807 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 2,128E-03 0,0264543 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,372E-03 0,02933502 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 2,372E-03 0,02917815 ! response to starvation GO:0042594 30 19 1,000 2,372E-03 0,02902295 ! sex determination GO:0007530 29 19 1,000 2,372E-03 0,02886939 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,372E-03 0,02871744 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 2,372E-03 0,02856709 ! protein stabilization GO:0050821 26 19 1,000 2,372E-03 0,0284183 ! lymphocyte differentiation GO:0030098 113 71 2,000 2,553E-03 0,03042507 ! multicellular organismal response to stress GO:0033555 32 20 1,000 2,629E-03 0,03117325 ! positive regulation of locomotion GO:0040017 35 20 1,000 2,629E-03 0,03101339 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,629E-03 0,03085516 ! response to hypoxia GO:0001666 132 72 2,000 2,657E-03 0,03101869 ! mitochondrion organization GO:0007005 104 73 2,000 2,763E-03 0,03209718 ! response to oxygen levels GO:0070482 137 74 2,000 2,872E-03 0,0331948 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 2,872E-03 0,03302882 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 2,899E-03 0,0331727 ! protein amino acid acylation GO:0043543 37 21 1,000 2,899E-03 0,03300848 ! regulation of chemotaxis GO:0050920 36 21 1,000 2,899E-03 0,03284587 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 2,899E-03 0,03268486 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,899E-03 0,03252542 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 2,899E-03 0,03236753 ! negative regulation of growth GO:0045926 123 75 2,000 2,984E-03 0,03315121 ! regulation of protein transport GO:0051223 114 76 2,000 3,098E-03 0,03425431 GO:0070201|regulation of establishment of protein localization, ! protein import into nucleus, translocation GO:0000060 36 22 1,000 3,181E-03 0,03500667 ! leukocyte adhesion GO:0007159 38 22 1,000 3,181E-03 0,03483997 ! vasculogenesis GO:0001570 33 22 1,000 3,181E-03 0,03467485 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 3,181E-03 0,03451129 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 3,181E-03 0,03434927 ! regulation of behavior GO:0050795 38 22 1,000 3,181E-03 0,03418876 ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 3,181E-03 0,03402974 ! regulation of DNA binding GO:0051101 119 77 2,000 3,215E-03 0,03422961 ! myelination GO:0042552 35 23 1,000 3,475E-03 0,03683611 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,475E-03 0,03666714 ! negative regulation of DNA replication GO:0008156 35 23 1,000 3,475E-03 0,03649971 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 3,475E-03 0,0363338 ! interaction with host GO:0051701 37 23 1,000 3,475E-03 0,03616939 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 3,475E-03 0,03600647 ! chromatin assembly GO:0031497 102 80 2,000 3,581E-03 0,03693624 GO:0006334|nucleosome assembly, ! regulation of cell cycle process GO:0010564 122 81 2,000 3,709E-03 0,03808193 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 3,782E-03 0,03866052 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 3,782E-03 0,03848946 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 3,782E-03 0,0383199 ! mitochondrial membrane organization GO:0007006 39 24 1,000 3,782E-03 0,03815183 ! negative regulation of cell development GO:0010721 56 24 1,000 3,782E-03 0,03798523 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 3,782E-03 0,03782007 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,782E-03 0,03765635 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 3,782E-03 0,03749404 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 3,782E-03 0,03733312 ! regulation of cell adhesion GO:0030155 159 83 2,000 3,972E-03 0,03904491 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 4,101E-03 0,04013497 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 4,101E-03 0,03996491 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 4,101E-03 0,03979628 ! protein-DNA complex assembly GO:0065004 107 84 2,000 4,108E-03 0,03970243 ! regulation of protein localization GO:0032880 132 85 2,000 4,247E-03 0,04087152 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 4,432E-03 0,04246884 ! regulation of pH GO:0006885 36 26 1,000 4,432E-03 0,04229262 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 4,432E-03 0,04211786 ! nucleosome organization GO:0034728 114 87 2,000 4,533E-03 0,04290547 ! skeletal muscle tissue development GO:0007519 123 87 2,000 4,533E-03 0,04272963 GO:0060538|skeletal muscle organ development, ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 1,000 4,774E-03 0,04481964 ! response to ionizing radiation GO:0010212 47 27 1,000 4,774E-03 0,04463745 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 4,774E-03 0,04445673 ! negative regulation of protein transport GO:0051224 49 27 1,000 4,774E-03 0,04427747 ! regulation of neurogenesis GO:0050767 153 89 2,000 4,83E-03 0,04461855 ! leukocyte differentiation GO:0002521 143 90 2,000 4,983E-03 0,04584781 ! cell junction assembly GO:0034329 56 28 1,000 5,129E-03 0,0469975 ! positive regulation of endocytosis GO:0045807 33 28 1,000 5,129E-03 0,046811 ! ensheathment of neurons GO:0007272 43 28 1,000 5,129E-03 0,04662598 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 5,129E-03 0,04644241 ! regulation of B cell activation GO:0050864 42 28 1,000 5,129E-03 0,04626028 ! cell fate commitment GO:0045165 141 92 2,000 5,298E-03 0,04760108 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 5,46E-03 0,04886357 ! regulation of binding GO:0051098 151 95 2,000 5,792E-03 0,05163731 ! negative regulation of cell activation GO:0050866 44 30 1,000 5,873E-03 0,05215617 ! DNA damage checkpoint GO:0000077 53 31 1,000 6,263E-03 0,05540208 ! mammary gland development GO:0030879 57 31 1,000 6,263E-03 0,05518981 ! maintenance of protein location in cell GO:0032507 60 31 1,000 6,263E-03 0,05497916 ! segmentation GO:0035282 41 31 1,000 6,263E-03 0,05477011 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 6,263E-03 0,05456265 ! RNA modification GO:0009451 40 31 1,000 6,263E-03 0,05435676 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 6,664E-03 0,0576205 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 6,664E-03 0,05740469 ! peripheral nervous system development GO:0007422 53 32 1,000 6,664E-03 0,05719049 ! regulation of protein stability GO:0031647 48 32 1,000 6,664E-03 0,05697789 ! calcium-mediated signaling GO:0019722 50 32 1,000 6,664E-03 0,05676686 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 6,664E-03 0,05655739 ! cell junction organization GO:0034330 63 33 1,000 7,076E-03 0,05983741 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 7,076E-03 0,05961822 ! carbohydrate homeostasis GO:0033500 39 33 1,000 7,076E-03 0,05940064 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 7,076E-03 0,05918464 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 7,5E-03 0,06250182 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 7,5E-03 0,06227618 ! DNA integrity checkpoint GO:0031570 57 34 1,000 7,5E-03 0,06205216 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 7,5E-03 0,06182976 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 7,5E-03 0,06160893 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 7,5E-03 0,06138969 ! keratinocyte differentiation GO:0030216 47 35 1,000 7,935E-03 0,06471994 ! regulation of action potential in neuron GO:0019228 54 35 1,000 7,935E-03 0,06449125 ! maintenance of protein location GO:0045185 65 35 1,000 7,935E-03 0,06426417 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 7,935E-03 0,06403868 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 7,935E-03 0,06381477 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 8,381E-03 0,06716772 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 8,381E-03 0,0669345 ! tissue remodeling GO:0048771 62 36 1,000 8,381E-03 0,06670289 ! hormone-mediated signaling GO:0009755 49 36 1,000 8,381E-03 0,06647288 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 9,307E-03 0,07355778 ! gliogenesis GO:0042063 71 38 1,000 9,307E-03 0,07330586 ! regulation of T cell proliferation GO:0042129 58 38 1,000 9,307E-03 0,07305567 ! maintenance of location in cell GO:0051651 69 38 1,000 9,307E-03 0,07280719 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 9,786E-03 0,07629482 ! JNK cascade GO:0007254 54 39 1,000 9,786E-03 0,07603706 ! synapse organization GO:0050808 55 39 1,000 9,786E-03 0,07578105 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,01027539 0,07930673 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,01027539 0,07904149 ! T cell differentiation GO:0030217 65 40 1,000 0,01027539 0,07877802 ! double-strand break repair GO:0006302 67 40 1,000 0,01027539 0,0785163 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,01027539 0,07825631 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,01027539 0,07799804 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,01027539 0,07774147 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01077583 0,08126039 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,01077583 0,08099484 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,01077583 0,08073101 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,01128687 0,0842851 ! mitochondrial transport GO:0006839 60 42 1,000 0,01128687 0,08401233 ! regulation of cell shape GO:0008360 78 42 1,000 0,01128687 0,08374133 ! positive regulation of binding GO:0051099 59 43 1,000 0,01180843 0,08732921 ! activation of caspase activity GO:0006919 65 43 1,000 0,01180843 0,08704931 ! tRNA processing GO:0008033 49 43 1,000 0,01180843 0,08677119 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01180843 0,08649485 ! regulation of action potential GO:0001508 71 44 1,000 0,01234041 0,09010457 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01288273 0,09376672 ! histone modification GO:0016570 68 46 1,000 0,01343531 0,09748019 ! regulation of ossification GO:0030278 71 46 1,000 0,01343531 0,09717365 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01399807 0,10092651 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01399807 0,10061112 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,01399807 0,10029769 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,01457091 0,10407795 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 1,000 0,01457091 0,10375573 ! regulation of endocytosis GO:0030100 63 48 1,000 0,01457091 0,1034355 ! nuclear export GO:0051168 69 48 1,000 0,01457091 0,10311723 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01457091 0,10280092 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01515377 0,10658612 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,01515377 0,10626116 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01574654 0,11008221 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01634916 0,1139487 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,01634916 0,11360444 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01696154 0,11750465 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,01696154 0,11715178 ! regulation of mitosis GO:0007088 84 54 1,000 0,01821525 0,12543438 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01821525 0,12505995 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01821525 0,12468775 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01901841 0,12979921 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01901841 0,12941519 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01901841 0,12903344 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01901841 0,12865393 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01901841 0,12827664 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01901841 0,12790157 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01901841 0,12752867 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01901841 0,12715795 ! sleep GO:0030431 11 5 0,000 0,01901841 0,12678938 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01901841 0,12642293 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01901841 0,1260586 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01901841 0,12569637 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01901841 0,1253362 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01901841 0,1249781 ! tongue development GO:0043586 6 5 0,000 0,01901841 0,12462204 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01901841 0,124268 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01901841 0,12391596 ! cobalt ion transport GO:0006824 9 5 0,000 0,01901841 0,12356592 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01901841 0,12321785 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01901841 0,12287173 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01901841 0,12252755 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01901841 0,12218529 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01901841 0,12184495 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01901841 0,12150649 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01901841 0,1211699 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01901841 0,12083518 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01901841 0,1205023 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01901841 0,12017125 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01901841 0,11984201 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01901841 0,11951458 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01901841 0,11918892 ! malate metabolic process GO:0006108 7 5 0,000 0,01901841 0,11886504 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01901841 0,11854291 ! behavioral response to pain GO:0048266 7 5 0,000 0,01901841 0,11822253 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01901841 0,11790387 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01901841 0,11758692 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01901841 0,11727168 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01901841 0,11695812 ! mating behavior GO:0007617 6 5 0,000 0,01901841 0,11664623 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01901841 0,116336 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01901841 0,11602741 ! rhythmic behavior GO:0007622 12 5 0,000 0,01901841 0,11572046 ! copulation GO:0007620 7 5 0,000 0,01901841 0,11541513 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01901841 0,11511141 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01901841 0,11480928 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01901841 0,11450873 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01901841 0,11420975 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01901841 0,11391233 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01901841 0,11361646 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01901841 0,11332211 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01901841 0,11302929 ! response to protozoan GO:0001562 9 5 0,000 0,01901841 0,11273798 ! lymph vessel development GO:0001945 7 5 0,000 0,01901841 0,11244816 ! endochondral ossification GO:0001958 12 5 0,000 0,01901841 0,11215983 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01901841 0,11187298 ! parathyroid gland development GO:0060017 8 5 0,000 0,01901841 0,11158759 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01901841 0,11130365 ! anagen GO:0042640 6 5 0,000 0,01901841 0,11102116 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01901841 0,11074009 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01901841 0,11046044 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01901841 0,1101822 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01901841 0,10990537 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01901841 0,10962991 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01901841 0,10935584 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01901841 0,10908313 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01901841 0,10881178 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01901841 0,10854178 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01901841 0,10827311 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01901841 0,10800577 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01901841 0,10773974 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01901841 0,10747503 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01901841 0,10721161 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01901841 0,10694948 ! ovulation GO:0030728 6 5 0,000 0,01901841 0,10668862 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01901841 0,10642904 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01901841 0,10617072 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01901841 0,10591364 ! response to pH GO:0009268 9 5 0,000 0,01901841 0,10565781 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01901841 0,10540322 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01901841 0,10514984 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01901841 0,10489769 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01901841 0,10464674 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01901841 0,10439698 ! polyol catabolic process GO:0046174 7 5 0,000 0,01901841 0,10414842 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01901841 0,10390103 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01901841 0,10365482 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01901841 0,10340978 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01901841 0,10316589 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01901841 0,10292314 ! urea metabolic process GO:0019627 6 5 0,000 0,01901841 0,10268154 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01901841 0,10244107 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01901841 0,10220172 ! neutrophil activation GO:0042119 5 5 0,000 0,01901841 0,10196349 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01901841 0,10172636 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01901841 0,10149034 ! response to food GO:0032094 5 5 0,000 0,01901841 0,10125541 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01901841 0,10102156 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01901841 0,10078879 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01901841 0,10055709 ! forebrain neuron development GO:0021884 7 5 0,000 0,01901841 0,10032646 ! melanosome organization GO:0032438 7 5 0,000 0,01901841 0,10009688 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01901841 0,09986835 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01901841 0,09964086 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01901841 0,0994144 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01901841 0,09918897 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01901841 0,09896456 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01901841 0,09874116 ! nucleoside transport GO:0015858 6 5 0,000 0,01901841 0,09851877 ! nucleoside salvage GO:0043174 7 5 0,000 0,01901841 0,09829738 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01901841 0,09807699 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01901841 0,09785757 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01901841 0,09763914 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01901841 0,09742168 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01901841 0,09720519 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01901841 0,09698966 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01901841 0,09677508 ! depyrimidination GO:0045008 8 5 0,000 0,01901841 0,09656145 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01901841 0,09634876 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01901841 0,096137 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01901841 0,09592617 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01901841 0,09571627 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01901841 0,09550728 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01901841 0,09529921 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01901841 0,09509203 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01901841 0,09488576 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01901841 0,09468038 ! monocyte differentiation GO:0030224 8 5 0,000 0,01901841 0,09447589 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01901841 0,09427227 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01901841 0,09406954 ! centrosome duplication GO:0051298 5 5 0,000 0,01901841 0,09386767 ! response to UV-C GO:0010225 6 5 0,000 0,01901841 0,09366667 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01901841 0,09346653 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01901841 0,09326724 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01901841 0,0930688 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01901841 0,0928712 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01901841 0,09267444 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01901841 0,09247851 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01901841 0,09228341 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01901841 0,09208913 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01901841 0,09189566 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01901841 0,09170301 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01901841 0,09151116 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01901841 0,09132012 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01901841 0,09112987 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01901841 0,09094041 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01901841 0,09075173 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01901841 0,09056384 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01901841 0,09037673 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01901841 0,09019038 ! neural tube patterning GO:0021532 6 5 0,000 0,01901841 0,09000481 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01901841 0,08981999 ! histone demethylation GO:0016577 9 5 0,000 0,01901841 0,08963593 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01901841 0,08945263 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01901841 0,08927007 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01901841 0,08908826 ! enteric nervous system development GO:0048484 8 5 0,000 0,01901841 0,08890719 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01901841 0,08872685 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01901841 0,08854724 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01901841 0,08836835 ! transcription termination GO:0006353 8 5 0,000 0,01901841 0,08819019 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01901841 0,08801275 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01901841 0,08783601 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01901841 0,08765999 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01901841 0,08748467 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01901841 0,08731005 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01901841 0,08713613 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01901841 0,08696289 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01901841 0,08679035 ! apical protein localization GO:0045176 6 5 0,000 0,01901841 0,08661849 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01901841 0,0864473 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01901841 0,0862768 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01901841 0,08610696 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01901841 0,08593779 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01901841 0,08576929 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01901841 0,08560144 ! glial cell migration GO:0008347 10 5 0,000 0,01901841 0,08543425 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01901841 0,08526771 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01901841 0,08510182 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01901841 0,08493657 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01901841 0,08477197 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01901841 0,084608 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01901841 0,08444466 ! neural plate development GO:0001840 6 5 0,000 0,01901841 0,08428196 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01901841 0,08411988 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01901841 0,08395842 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01901841 0,08379758 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01901841 0,08363735 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01901841 0,08347774 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01901841 0,08331873 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01901841 0,08316033 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01901841 0,08300253 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01901841 0,08284533 ! spindle assembly GO:0051225 5 5 0,000 0,01901841 0,08268872 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01901841 0,08253271 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01901841 0,08237728 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01901841 0,08222243 ! organ regeneration GO:0031100 7 5 0,000 0,01901841 0,08206817 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01901841 0,08191449 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01901841 0,08176137 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01901841 0,08160883 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01901841 0,08145686 GO:0055081|anion homeostasis, ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,02016701 0,08621584 ! viral reproductive process GO:0022415 87 58 1,000 0,02083626 0,08891168 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,02083626 0,08874703 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,02220228 0,09439048 ! tRNA transcription GO:0009304 11 6 0,000 0,02277911 0,09666411 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02277911 0,09648609 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02277911 0,09630873 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02277911 0,09613201 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02277911 0,09595595 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02277911 0,09578052 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02277911 0,09560574 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02277911 0,0954316 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02277911 0,09525809 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02277911 0,0950852 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02277911 0,09491295 ! prostate gland development GO:0030850 9 6 0,000 0,02277911 0,09474131 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02277911 0,0945703 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02277911 0,0943999 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02277911 0,09423012 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02277911 0,09406095 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02277911 0,09389238 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02277911 0,09372441 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02277911 0,09355705 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02277911 0,09339028 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02277911 0,09322411 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02277911 0,09305852 ! neuron adhesion GO:0007158 9 6 0,000 0,02277911 0,09289352 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02277911 0,09272911 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02277911 0,09256528 ! signal peptide processing GO:0006465 8 6 0,000 0,02277911 0,09240202 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02277911 0,09223934 ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02277911 0,09207724 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02277911 0,0919157 ! opsonization GO:0008228 8 6 0,000 0,02277911 0,09175472 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02277911 0,09159431 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02277911 0,09143446 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02277911 0,09127517 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02277911 0,09111643 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02277911 0,09095824 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02277911 0,0908006 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02277911 0,09064351 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02277911 0,09048696 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02277911 0,09033094 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02277911 0,09017547 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02277911 0,09002053 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02277911 0,08986612 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02277911 0,08971224 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02277911 0,08955888 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02277911 0,08940605 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02277911 0,08925374 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02277911 0,08910195 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02277911 0,08895067 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02277911 0,08879991 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02277911 0,08864966 ! thymic T cell selection GO:0045061 12 6 0,000 0,02277911 0,08849991 ! protein lipoylation GO:0009249 10 6 0,000 0,02277911 0,08835067 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02277911 0,08820193 ! pigment granule organization GO:0048753 11 6 0,000 0,02277911 0,08805369 ! drug transport GO:0015893 6 6 0,000 0,02277911 0,08790595 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02277911 0,08775871 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02277911 0,08761195 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02277911 0,08746569 ! histidine metabolic process GO:0006547 6 6 0,000 0,02277911 0,08731991 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02277911 0,08717462 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02277911 0,08702981 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02277911 0,08688548 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02277911 0,08674163 ! adenohypophysis development GO:0021984 10 6 0,000 0,02277911 0,08659826 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02277911 0,08645536 ! hyperosmotic response GO:0006972 8 6 0,000 0,02277911 0,08631293 ! microtubule nucleation GO:0007020 10 6 0,000 0,02277911 0,08617097 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02277911 0,08602947 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02277911 0,08588844 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02277911 0,08574787 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02277911 0,08560776 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02277911 0,0854681 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02277911 0,0853289 ! response to dietary excess GO:0002021 7 6 0,000 0,02277911 0,08519016 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02277911 0,08505186 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02277911 0,08491401 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02277911 0,08477661 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02277911 0,08463966 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02277911 0,08450314 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02277911 0,08436706 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02277911 0,08423143 ! neuron apoptosis GO:0051402 8 6 0,000 0,02277911 0,08409622 ! organic alcohol transport GO:0015850 9 6 0,000 0,02277911 0,08396145 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02277911 0,08382712 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02277911 0,08369321 ! carnitine transport GO:0015879 8 6 0,000 0,02277911 0,08355972 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02277911 0,08342667 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02277911 0,08329403 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02277911 0,08316182 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02277911 0,08303003 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02277911 0,08289865 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02277911 0,08276769 ! parturition GO:0007567 12 6 0,000 0,02277911 0,08263714 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02277911 0,082507 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02277911 0,08237728 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02277911 0,08224795 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02277911 0,08211904 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02277911 0,08199053 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02277911 0,08186242 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02277911 0,08173471 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02277911 0,08160739 ! macrophage differentiation GO:0030225 10 6 0,000 0,02277911 0,08148048 ! astrocyte development GO:0014002 14 6 0,000 0,02277911 0,08135396 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02277911 0,08122782 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02277911 0,08110209 ! interaction with symbiont GO:0051702 8 6 0,000 0,02277911 0,08097673 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02277911 0,08085177 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02277911 0,08072719 ! eating behavior GO:0042755 6 6 0,000 0,02277911 0,080603 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02277911 0,08047918 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02277911 0,08035575 ! response to copper ion GO:0046688 9 6 0,000 0,02277911 0,08023269 ! DNA topological change GO:0006265 8 6 0,000 0,02277911 0,08011001 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02277911 0,07998771 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02277911 0,07986577 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02277911 0,07974421 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02277911 0,07962302 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02277911 0,0795022 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02277911 0,07938174 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02277911 0,07926164 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02277911 0,07914191 ! gas homeostasis GO:0033483 11 6 0,000 0,02277911 0,07902254 ! hair follicle maturation GO:0048820 7 6 0,000 0,02277911 0,07890353 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02277911 0,07878488 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02277911 0,07866659 ! Schwann cell development GO:0014044 14 6 0,000 0,02277911 0,07854865 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02277911 0,07843106 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02277911 0,07831382 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02277911 0,07819694 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02277911 0,0780804 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02277911 0,07796421 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02277911 0,07784836 ! histone ubiquitination GO:0016574 7 6 0,000 0,02277911 0,07773286 ! G2 phase GO:0051319 13 6 0,000 0,02277911 0,0776177 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02277911 0,07750288 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02277911 0,0773884 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02277911 0,07727426 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02277911 0,07716045 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02277911 0,07704698 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02277911 0,07693384 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02277911 0,07682104 ! receptor internalization GO:0031623 9 6 0,000 0,02277911 0,07670856 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02277911 0,07659641 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02277911 0,07648459 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02277911 0,0763731 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02277911 0,07626193 ! protein deubiquitination GO:0016579 8 6 0,000 0,02277911 0,07615109 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02277911 0,07604056 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02277911 0,07593036 ! axonal fasciculation GO:0007413 9 6 0,000 0,02277911 0,07582047 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02277911 0,07571091 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02277911 0,07560166 ! midbrain development GO:0030901 6 6 0,000 0,02277911 0,07549272 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02277911 0,0753841 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02277911 0,07527579 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02277911 0,07516779 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02277911 0,0750601 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02277911 0,07495271 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02277911 0,07484564 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02277911 0,07473887 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02277911 0,0746324 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02277911 0,07452624 ! adult feeding behavior GO:0008343 6 6 0,000 0,02277911 0,07442038 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02277911 0,07431482 ! blastocyst growth GO:0001832 15 6 0,000 0,02277911 0,07420956 ! pigment granule transport GO:0051904 12 6 0,000 0,02277911 0,07410459 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02277911 0,07399993 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02277911 0,07389555 ! catecholamine transport GO:0051937 7 6 0,000 0,02277911 0,07379147 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02277911 0,07368769 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02277911 0,0735842 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02277911 0,07348099 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02277911 0,07337808 ! protein prenylation GO:0018342 10 6 0,000 0,02277911 0,07327545 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02277911 0,07317311 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02277911 0,07307106 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02277911 0,07296929 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02277911 0,0728678 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,0228989 0,07314926 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02431896 0,07757782 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,02431896 0,07747038 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,02431896 0,07736322 ! viral reproduction GO:0016032 92 63 1,000 0,02431896 0,07725637 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02431896 0,07714981 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,02504225 0,07933496 ! adaptive immune response GO:0002250 94 64 1,000 0,02504225 0,07922583 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,02577428 0,08142974 ! antigen processing and presentation GO:0019882 96 66 1,000 0,02651498 0,08365493 ! axon guidance GO:0007411 99 66 1,000 0,02651498 0,08354034 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02652561 0,0834595 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02652561 0,08334548 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02652561 0,08323178 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02652561 0,08311838 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02652561 0,0830053 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02652561 0,08289252 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02652561 0,08278004 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02652561 0,08266788 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02652561 0,08255601 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02652561 0,08244445 ! reproductive behavior GO:0019098 12 7 0,000 0,02652561 0,08233319 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02652561 0,08222223 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02652561 0,08211156 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02652561 0,0820012 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02652561 0,08189113 ! oligopeptide transport GO:0006857 11 7 0,000 0,02652561 0,08178136 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02652561 0,08167188 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02652561 0,08156269 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02652561 0,0814538 ! RNA methylation GO:0001510 11 7 0,000 0,02652561 0,08134519 ! pericardium development GO:0060039 8 7 0,000 0,02652561 0,08123687 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02652561 0,08112885 ! fibril organization GO:0043206 13 7 0,000 0,02652561 0,08102111 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02652561 0,08091365 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02652561 0,08080648 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02652561 0,08069959 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02652561 0,08059299 ! lipoprotein transport GO:0042953 9 7 0,000 0,02652561 0,08048667 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02652561 0,08038062 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02652561 0,08027486 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02652561 0,08016937 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02652561 0,08006416 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02652561 0,07995923 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02652561 0,07985457 ! chemosensory behavior GO:0007635 9 7 0,000 0,02652561 0,07975019 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02652561 0,07964607 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02652561 0,07954223 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02652561 0,07943866 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02652561 0,07933536 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02652561 0,07923233 ! reflex GO:0060004 12 7 0,000 0,02652561 0,07912956 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02652561 0,07902706 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02652561 0,07892483 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02652561 0,07882286 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02652561 0,07872115 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02652561 0,07861971 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02652561 0,07851852 ! spinal cord patterning GO:0021511 7 7 0,000 0,02652561 0,0784176 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02652561 0,07831694 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02652561 0,07821653 ! adrenal gland development GO:0030325 17 7 0,000 0,02652561 0,07811638 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02652561 0,07801649 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02652561 0,07791685 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02652561 0,07781747 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02652561 0,07771833 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02652561 0,07761946 ! endosome organization GO:0007032 10 7 0,000 0,02652561 0,07752083 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02652561 0,07742245 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02652561 0,07732433 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02652561 0,07722645 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02652561 0,07712881 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02652561 0,07703143 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02652561 0,07693429 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02652561 0,0768374 ! galactose metabolic process GO:0006012 10 7 0,000 0,02652561 0,07674075 ! vesicle fusion GO:0006906 15 7 0,000 0,02652561 0,07664434 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02652561 0,07654817 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02652561 0,07645225 ! organ growth GO:0035265 11 7 0,000 0,02652561 0,07635656 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02652561 0,07626112 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02652561 0,07616591 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02652561 0,07607094 ! retinol metabolic process GO:0042572 9 7 0,000 0,02652561 0,0759762 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02652561 0,07588171 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02652561 0,07578744 ! rRNA modification GO:0000154 12 7 0,000 0,02652561 0,07569342 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02652561 0,07559962 ! response to UV-B GO:0010224 11 7 0,000 0,02652561 0,07550606 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02652561 0,07541272 ! intermediate filament organization GO:0045109 11 7 0,000 0,02652561 0,07531962 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02652561 0,07522675 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02652561 0,0751341 ! fibrinolysis GO:0042730 9 7 0,000 0,02652561 0,07504169 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02652561 0,0749495 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02652561 0,07485754 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02652561 0,0747658 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02652561 0,07467429 ! response to tropane GO:0014073 13 7 0,000 0,02652561 0,074583 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02652561 0,07449193 ! melanosome localization GO:0032400 10 7 0,000 0,02652561 0,07440109 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02652561 0,07431047 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02652561 0,07422006 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02652561 0,07412988 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02652561 0,07403992 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02652561 0,07395017 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02652561 0,07386064 ! mast cell activation GO:0045576 9 7 0,000 0,02652561 0,07377133 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02652561 0,07368224 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02652561 0,07359336 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02652561 0,07350469 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02652561 0,07341624 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02652561 0,073328 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02652561 0,07323997 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02652561 0,07315215 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02652561 0,07306454 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02652561 0,07297714 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02652561 0,07288996 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02652561 0,07280297 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02652561 0,0727162 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02652561 0,07262963 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02652561 0,07254327 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02652561 0,07245712 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02652561 0,07237117 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02652561 0,07228542 ! diuresis GO:0030146 12 7 0,000 0,02652561 0,07219987 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02652561 0,07211453 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02652561 0,07202939 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02652561 0,07194445 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02652561 0,07185971 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02652561 0,07177517 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02652561 0,07169083 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02652561 0,07160668 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02652561 0,07152273 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02652561 0,07143898 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02652561 0,07135543 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02652561 0,07127207 ! lymph node development GO:0048535 9 7 0,000 0,02652561 0,07118891 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02652561 0,07110594 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02652561 0,07102316 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02652561 0,07094057 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02652561 0,07085818 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02652561 0,07077598 ! ATP catabolic process GO:0006200 10 7 0,000 0,02652561 0,07069397 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02652561 0,07061214 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02652561 0,07053051 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02652561 0,07044907 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02652561 0,07036781 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02652561 0,07028674 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02652561 0,07020586 ! muscle adaptation GO:0043500 12 7 0,000 0,02652561 0,07012516 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02652561 0,07004465 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02652561 0,06996433 ! retina homeostasis GO:0001895 9 7 0,000 0,02652561 0,06988418 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02652561 0,06980422 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02652561 0,06972445 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02652561 0,06964485 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02652561 0,06956544 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02652561 0,06948621 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02652561 0,06940716 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02652561 0,06932829 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,02726426 0,07117797 ! learning or memory GO:0007611 123 68 1,000 0,02802205 0,07307338 ! response to drug GO:0042493 108 69 1,000 0,02878829 0,07498648 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,02956289 0,07691702 ! humoral immune response GO:0006959 86 70 1,000 0,02956289 0,07683011 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,02956289 0,07674339 ! regulation of catabolic process GO:0009894 106 70 1,000 0,02956289 0,07665687 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03025795 0,07837083 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03025795 0,07828267 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,03025795 0,07819471 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03025795 0,07810695 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03025795 0,07801939 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03025795 0,07793202 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03025795 0,07784485 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03025795 0,07775787 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03025795 0,07767109 ! phosphate transport GO:0006817 10 8 0,000 0,03025795 0,0775845 ! N-glycan processing GO:0006491 12 8 0,000 0,03025795 0,0774981 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03025795 0,07741189 ! UTP metabolic process GO:0046051 8 8 0,000 0,03025795 0,07732588 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03025795 0,07724006 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03025795 0,07715443 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03025795 0,07706898 ! succinate metabolic process GO:0006105 14 8 0,000 0,03025795 0,07698373 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03025795 0,07689867 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03025795 0,07681379 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03025795 0,0767291 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03025795 0,0766446 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03025795 0,07656028 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03025795 0,07647615 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03025795 0,0763922 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03025795 0,07630844 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03025795 0,07622486 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03025795 0,07614146 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03025795 0,07605824 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03025795 0,07597521 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03025795 0,07589236 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03025795 0,07580969 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03025795 0,0757272 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,03025795 0,07564488 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03025795 0,07556275 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03025795 0,0754808 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03025795 0,07539902 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03025795 0,07531742 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03025795 0,07523599 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03025795 0,07515474 ! melanin metabolic process GO:0006582 12 8 0,000 0,03025795 0,07507367 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03025795 0,07499277 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03025795 0,07491205 ! macrophage activation GO:0042116 12 8 0,000 0,03025795 0,0748315 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03025795 0,07475112 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03025795 0,07467092 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03025795 0,07459088 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03025795 0,07451102 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03025795 0,07443133 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03025795 0,07435181 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03025795 0,07427246 ! ruffle organization GO:0031529 11 8 0,000 0,03025795 0,07419328 ! osteoblast development GO:0002076 13 8 0,000 0,03025795 0,07411426 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03025795 0,07403542 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03025795 0,07395674 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03025795 0,07387823 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03025795 0,07379989 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03025795 0,07372171 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03025795 0,0736437 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03025795 0,07356585 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03025795 0,07348817 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03025795 0,07341065 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03025795 0,07333329 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03025795 0,0732561 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03025795 0,07317907 ! segment specification GO:0007379 10 8 0,000 0,03025795 0,0731022 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03025795 0,07302549 ! cellular extravasation GO:0045123 11 8 0,000 0,03025795 0,07294894 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03025795 0,07287256 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03025795 0,07279633 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03025795 0,07272026 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03025795 0,07264436 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03025795 0,07256861 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03025795 0,07249301 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03025795 0,07241758 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03025795 0,0723423 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03025795 0,07226718 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03025795 0,07219221 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03025795 0,0721174 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03025795 0,07204275 ! icosanoid secretion GO:0032309 12 8 0,000 0,03025795 0,07196825 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03025795 0,0718939 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03025795 0,0718197 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03025795 0,07174566 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03025795 0,07167177 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03025795 0,07159804 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03025795 0,07152445 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03025795 0,07145102 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03025795 0,07137774 ! sterol catabolic process GO:0016127 9 8 0,000 0,03025795 0,0713046 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03025795 0,07123162 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03025795 0,07115879 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03025795 0,0710861 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03025795 0,07101356 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03025795 0,07094118 ! prophase GO:0051324 11 8 0,000 0,03025795 0,07086893 ! S phase GO:0051320 8 8 0,000 0,03025795 0,07079684 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03025795 0,07072489 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03025795 0,07065309 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03025795 0,07058143 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03025795 0,07050992 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03025795 0,07043856 ! hormone catabolic process GO:0042447 13 8 0,000 0,03025795 0,07036733 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03025795 0,07029626 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03025795 0,07022532 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03025795 0,07015453 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03025795 0,07008388 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03025795 0,07001337 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03025795 0,06994301 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03025795 0,06987278 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03025795 0,0698027 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03025795 0,06973276 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03025795 0,06966296 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03025795 0,06959329 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03025795 0,06952377 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03025795 0,06945438 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03025795 0,06938514 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,03034578 0,06951723 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,0311369 0,07125857 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 116 73 1,000 0,03193616 0,07301507 ! protein import into nucleus GO:0006606 118 74 1,000 0,03274349 0,07478653 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,03274349 0,07471234 ! nuclear import GO:0051170 121 75 1,000 0,03355883 0,07649684 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0339762 0,07737156 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0339762 0,07729503 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0339762 0,07721865 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0339762 0,07714242 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0339762 0,07706634 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0339762 0,07699041 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0339762 0,07691464 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,0339762 0,07683901 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,0339762 0,07676353 ! GTP metabolic process GO:0046039 9 9 0,000 0,0339762 0,07668819 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0339762 0,07661301 ! social behavior GO:0035176 14 9 0,000 0,0339762 0,07653797 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,0339762 0,07646308 ! artery development GO:0060840 19 9 0,000 0,0339762 0,07638834 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,0339762 0,07631374 ! response to pain GO:0048265 16 9 0,000 0,0339762 0,07623929 ! protein complex disassembly GO:0043241 17 9 0,000 0,0339762 0,07616498 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0339762 0,07609082 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0339762 0,0760168 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0339762 0,07594293 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,0339762 0,07586919 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0339762 0,07579561 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0339762 0,07572216 ! ventral spinal cord development GO:0021517 11 9 0,000 0,0339762 0,07564886 ! protein targeting to ER GO:0045047 19 9 0,000 0,0339762 0,0755757 ! T cell selection GO:0045058 18 9 0,000 0,0339762 0,07550268 ! endoderm development GO:0007492 12 9 0,000 0,0339762 0,0754298 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0339762 0,07535706 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0339762 0,07528446 ! arginine catabolic process GO:0006527 10 9 0,000 0,0339762 0,075212 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0339762 0,07513968 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0339762 0,0750675 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0339762 0,07499546 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0339762 0,07492356 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0339762 0,07485179 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,0339762 0,07478016 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,0339762 0,07470867 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,0339762 0,07463732 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0339762 0,0745661 ! mannose metabolic process GO:0006013 9 9 0,000 0,0339762 0,07449501 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0339762 0,07442407 ! receptor clustering GO:0043113 15 9 0,000 0,0339762 0,07435325 ! epithelial cell development GO:0002064 10 9 0,000 0,0339762 0,07428258 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0339762 0,07421203 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0339762 0,07414162 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0339762 0,07407135 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0339762 0,0740012 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0339762 0,07393119 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0339762 0,07386131 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0339762 0,07379157 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,0339762 0,07372195 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0339762 0,07365247 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0339762 0,07358312 ! DNA ligation GO:0006266 14 9 0,000 0,0339762 0,0735139 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0339762 0,0734448 ! response to amine stimulus GO:0014075 13 9 0,000 0,0339762 0,07337584 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0339762 0,07330701 ! erythrocyte development GO:0048821 11 9 0,000 0,0339762 0,0732383 ! renal water homeostasis GO:0003091 14 9 0,000 0,0339762 0,07316973 ! postreplication repair GO:0006301 11 9 0,000 0,0339762 0,07310128 ! mRNA cleavage GO:0006379 13 9 0,000 0,0339762 0,07303296 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0339762 0,07296477 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0339762 0,07289671 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0339762 0,07282877 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0339762 0,07276096 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,0339762 0,07269327 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,0339762 0,07262572 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,0339762 0,07255828 ! acid secretion GO:0046717 14 9 0,000 0,0339762 0,07249097 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0339762 0,07242379 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0339762 0,07235673 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0339762 0,0722898 ! purine base metabolic process GO:0006144 18 9 0,000 0,0339762 0,07222299 ! oocyte differentiation GO:0009994 12 9 0,000 0,0339762 0,0721563 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,0339762 0,07208973 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,0339762 0,07202329 ! spleen development GO:0048536 15 9 0,000 0,0339762 0,07195697 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0339762 0,07189077 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0339762 0,0718247 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0339762 0,07175874 ! detection of calcium ion GO:0005513 13 9 0,000 0,0339762 0,07169291 ! blastocyst formation GO:0001825 12 9 0,000 0,0339762 0,0716272 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0339762 0,0715616 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0339762 0,07149613 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0339762 0,07143078 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0339762 0,07136554 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0339762 0,07130043 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0339762 0,07123543 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0339762 0,07117056 ! prepulse inhibition GO:0060134 14 9 0,000 0,0339762 0,0711058 ! embryonic placenta development GO:0001892 12 9 0,000 0,0339762 0,07104116 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0339762 0,07097663 ! insulin secretion GO:0030073 17 9 0,000 0,0339762 0,07091222 ! response to nicotine GO:0035094 16 9 0,000 0,0339762 0,07084793 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0339762 0,07078376 ! nucleus localization GO:0051647 15 9 0,000 0,0339762 0,0707197 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0339762 0,07065576 ! tRNA metabolic process GO:0006399 95 76 1,000 0,0343821 0,07143527 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,0343821 0,07137079 ! gland development GO:0048732 148 77 1,000 0,03521324 0,07303016 ! protein ubiquitination GO:0016567 125 77 1,000 0,03521324 0,07296437 ! T cell activation GO:0042110 134 79 1,000 0,03689881 0,07638817 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03768041 0,0779361 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03768041 0,07786608 ! neuron fate specification GO:0048665 11 10 0,000 0,03768041 0,07779618 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03768041 0,07772641 ! thyroid gland development GO:0030878 19 10 0,000 0,03768041 0,07765676 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03768041 0,07758724 ! synapsis GO:0007129 13 10 0,000 0,03768041 0,07751784 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03768041 0,07744857 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03768041 0,07737941 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03768041 0,07731039 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03768041 0,07724148 ! sulfate transport GO:0008272 12 10 0,000 0,03768041 0,0771727 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03768041 0,07710404 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03768041 0,07703551 ! androgen metabolic process GO:0008209 13 10 0,000 0,03768041 0,07696709 ! phospholipid efflux GO:0033700 16 10 0,000 0,03768041 0,0768988 ! hippocampus development GO:0021766 19 10 0,000 0,03768041 0,07683062 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03768041 0,07676257 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03768041 0,07669464 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03768041 0,07662683 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03768041 0,07655914 ! pathogenesis GO:0009405 13 10 0,000 0,03768041 0,07649157 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03768041 0,07642411 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03768041 0,07635678 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03768041 0,07628956 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03768041 0,07622247 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03768041 0,07615549 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03768041 0,07608863 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03768041 0,07602188 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03768041 0,07595525 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03768041 0,07588874 ! B cell proliferation GO:0042100 14 10 0,000 0,03768041 0,07582235 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03768041 0,07575607 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03768041 0,07568991 ! forebrain cell migration GO:0021885 17 10 0,000 0,03768041 0,07562386 ! lipid digestion GO:0044241 15 10 0,000 0,03768041 0,07555793 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03768041 0,07549211 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03768041 0,07542641 ! UV protection GO:0009650 14 10 0,000 0,03768041 0,07536082 ! entry into host cell GO:0030260 20 10 0,000 0,03768041 0,07529535 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03768041 0,07522999 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03768041 0,07516474 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03768041 0,07509961 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03768041 0,07503458 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03768041 0,07496968 ! regulation of organ growth GO:0046620 11 10 0,000 0,03768041 0,07490488 ! response to dsRNA GO:0043331 18 10 0,000 0,03768041 0,07484019 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03768041 0,07477562 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03768041 0,07471116 ! embryonic axis specification GO:0000578 12 10 0,000 0,03768041 0,07464681 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03768041 0,07458257 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03768041 0,07451844 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03768041 0,07445442 ! cranial nerve development GO:0021545 12 10 0,000 0,03768041 0,07439051 ! fucose catabolic process GO:0019317 16 10 0,000 0,03768041 0,07432671 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03768041 0,07426302 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03768041 0,07419944 ! protein sumoylation GO:0016925 12 10 0,000 0,03768041 0,07413597 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03768041 0,0740726 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03768041 0,07400935 ! zymogen activation GO:0031638 14 10 0,000 0,03768041 0,0739462 ! salivary gland development GO:0007431 22 10 0,000 0,03768041 0,07388316 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03768041 0,07382023 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03768041 0,0737574 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03768041 0,07369468 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03768041 0,07363207 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03768041 0,07356956 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03768041 0,07350716 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03768041 0,07344487 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03768041 0,07338268 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03768041 0,0733206 ! detection of bacterium GO:0016045 10 10 0,000 0,03768041 0,07325862 ! embryonic gut development GO:0048566 11 10 0,000 0,03768041 0,07319674 ! activation of innate immune response GO:0002218 10 10 0,000 0,03768041 0,07313497 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03768041 0,07307331 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03768041 0,07301175 ! developmental induction GO:0031128 13 10 0,000 0,03768041 0,07295029 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03768041 0,07288894 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03768041 0,07282768 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03768041 0,07276654 ! protein localization in nucleus GO:0034504 133 80 1,000 0,03775311 0,07284576 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,03861499 0,07444632 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,03948438 0,07605869 GO:0060348|bone development, ! rRNA transcription GO:0009303 17 11 0,000 0,04137062 0,07962547 ! respiratory burst GO:0045730 14 11 0,000 0,04137062 0,07955889 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04137062 0,07949243 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04137062 0,07942607 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04137062 0,07935983 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,04137062 0,0792937 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04137062 0,07922767 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04137062 0,07916176 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04137062 0,07909596 ! mating GO:0007618 14 11 0,000 0,04137062 0,07903026 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04137062 0,07896468 ! T cell proliferation GO:0042098 20 11 0,000 0,04137062 0,0788992 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04137062 0,07883383 ! bone resorption GO:0045453 16 11 0,000 0,04137062 0,07876857 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04137062 0,07870342 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04137062 0,07863838 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04137062 0,07857344 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04137062 0,07850861 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04137062 0,07844389 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04137062 0,07837927 ! syncytium formation GO:0006949 15 11 0,000 0,04137062 0,07831476 ! plasma membrane organization GO:0007009 18 11 0,000 0,04137062 0,07825036 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04137062 0,07818606 ! focal adhesion formation GO:0048041 24 11 0,000 0,04137062 0,07812187 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04137062 0,07805778 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04137062 0,0779938 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04137062 0,07792992 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04137062 0,07786615 ! adult heart development GO:0007512 11 11 0,000 0,04137062 0,07780248 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04137062 0,07773892 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04137062 0,07767546 ! temperature homeostasis GO:0001659 16 11 0,000 0,04137062 0,0776121 ! L-glutamate transport GO:0015813 16 11 0,000 0,04137062 0,07754885 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04137062 0,0774857 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04137062 0,07742265 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04137062 0,0773597 ! stem cell development GO:0048864 29 11 0,000 0,04137062 0,07729686 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04137062 0,07723412 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04137062 0,07717148 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04137062 0,07710894 ! vasoconstriction GO:0042310 15 11 0,000 0,04137062 0,07704651 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04137062 0,07698417 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04137062 0,07692194 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04137062 0,0768598 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04137062 0,07679777 ! ribosome assembly GO:0042255 13 11 0,000 0,04137062 0,07673584 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04137062 0,076674 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04137062 0,07661227 ! chromatin silencing GO:0006342 19 11 0,000 0,04137062 0,07655063 ! nucleosome positioning GO:0016584 13 11 0,000 0,04137062 0,0764891 ! T cell homeostasis GO:0043029 20 11 0,000 0,04137062 0,07642766 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04137062 0,07636632 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04137062 0,07630508 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04137062 0,07624394 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04137062 0,0761829 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04137062 0,07612195 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04137062 0,0760611 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04137062 0,07600035 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04137062 0,07593969 ! male genitalia development GO:0030539 13 11 0,000 0,04137062 0,07587914 ! cholesterol efflux GO:0033344 19 11 0,000 0,04137062 0,07581867 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04137062 0,07575831 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04137062 0,07569804 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04137062 0,07563787 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04137062 0,07557779 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04137062 0,07551781 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04137062 0,07545792 ! defense response to fungus GO:0050832 12 11 0,000 0,04137062 0,07539813 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04137062 0,07533843 ! lysogeny GO:0030069 18 11 0,000 0,04137062 0,07527883 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04137062 0,07521932 ! acrosome reaction GO:0007340 13 11 0,000 0,04137062 0,0751599 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04137062 0,07510058 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,04213696 0,0764314 ! regulation of membrane potential GO:0042391 128 85 1,000 0,04213696 0,07637117 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,04213696 0,07631103 ! lactation GO:0007595 20 12 0,000 0,0450469 0,08151681 ! reproductive cellular process GO:0048610 14 12 0,000 0,0450469 0,08145272 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0450469 0,08138874 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0450469 0,08132485 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0450469 0,08126107 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0450469 0,08119739 ! non-recombinational repair GO:0000726 19 12 0,000 0,0450469 0,0811338 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0450469 0,08107032 ! peroxisomal transport GO:0043574 21 12 0,000 0,0450469 0,08100693 ! cartilage condensation GO:0001502 18 12 0,000 0,0450469 0,08094364 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0450469 0,08088046 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0450469 0,08081737 ! heart looping GO:0001947 15 12 0,000 0,0450469 0,08075438 ! palate development GO:0060021 15 12 0,000 0,0450469 0,08069148 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0450469 0,08062869 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,0450469 0,08056599 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0450469 0,08050339 ! arginine metabolic process GO:0006525 13 12 0,000 0,0450469 0,08044089 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0450469 0,08037848 ! methionine metabolic process GO:0006555 13 12 0,000 0,0450469 0,08031617 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0450469 0,08025396 ! Golgi organization GO:0007030 18 12 0,000 0,0450469 0,08019185 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,0450469 0,08012983 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0450469 0,0800679 ! monoamine transport GO:0015844 13 12 0,000 0,0450469 0,08000607 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0450469 0,07994434 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0450469 0,0798827 ! L-amino acid transport GO:0015807 20 12 0,000 0,0450469 0,07982116 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0450469 0,07975971 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0450469 0,07969836 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0450469 0,0796371 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0450469 0,07957593 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0450469 0,07951486 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0450469 0,07945388 ! cerebellum development GO:0021549 13 12 0,000 0,0450469 0,079393 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0450469 0,07933221 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0450469 0,07927151 ! histone methylation GO:0016571 15 12 0,000 0,0450469 0,07921091 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0450469 0,07915039 ! gland morphogenesis GO:0022612 23 12 0,000 0,0450469 0,07908997 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0450469 0,07902964 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0450469 0,07896941 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0450469 0,07890926 ! intestinal absorption GO:0050892 19 12 0,000 0,0450469 0,07884921 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0450469 0,07878925 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0450469 0,07872938 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,0450469 0,0786696 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0450469 0,07860991 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,0450469 0,07855031 ! microspike assembly GO:0030035 23 12 0,000 0,0450469 0,07849081 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0450469 0,07843139 ! response to cold GO:0009409 14 12 0,000 0,0450469 0,07837206 ! reproductive developmental process GO:0003006 127 89 1,000 0,04577483 0,07957831 ! regulation of T cell activation GO:0050863 128 89 1,000 0,04577483 0,07951821 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,04670191 0,08106746 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04870928 0,0844882 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04870928 0,08442453 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04870928 0,08436096 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04870928 0,08429748 ! water transport GO:0006833 17 13 0,000 0,04870928 0,0842341 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04870928 0,08417081 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04870928 0,08410762 ! lipid localization GO:0010876 24 13 0,000 0,04870928 0,08404452 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04870928 0,08398152 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04870928 0,08391861 ! organelle fusion GO:0048284 28 13 0,000 0,04870928 0,0838558 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04870928 0,08379308 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04870928 0,08373045 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04870928 0,08366792 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04870928 0,08360548 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04870928 0,08354314 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04870928 0,08348089 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04870928 0,08341873 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04870928 0,08335666 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04870928 0,08329468 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04870928 0,0832328 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04870928 0,08317101 ! NAD metabolic process GO:0019674 21 13 0,000 0,04870928 0,08310931 ! exocrine system development GO:0035272 27 13 0,000 0,04870928 0,0830477 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04870928 0,08298618 ! bone mineralization GO:0030282 15 13 0,000 0,04870928 0,08292476 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04870928 0,08286342 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04870928 0,08280218 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04870928 0,08274103 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04870928 0,08267996 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04870928 0,08261899 ! genitalia development GO:0048806 15 13 0,000 0,04870928 0,08255811 ! cellular pigmentation GO:0033059 24 13 0,000 0,04870928 0,08249731 ! tissue regeneration GO:0042246 21 13 0,000 0,04870928 0,08243661 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04870928 0,08237599 ! cofactor transport GO:0051181 19 13 0,000 0,04870928 0,08231547 ! NADP metabolic process GO:0006739 18 13 0,000 0,04870928 0,08225503 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04870928 0,08219468 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04870928 0,08213442 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04870928 0,08207425 ! gas transport GO:0015669 18 13 0,000 0,04870928 0,08201416 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04870928 0,08195417 ! regulation of axon extension GO:0030516 23 13 0,000 0,04870928 0,08189426 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04870928 0,08183444 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04870928 0,08177471 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04870928 0,08171506 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04870928 0,0816555 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04870928 0,08159603 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04870928 0,08153664 ! angiogenesis GO:0001525 149 95 1,000 0,05143969 0,08604457 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05235783 0,08751672 ! superoxide anion generation GO:0042554 18 14 0,000 0,05235783 0,08745317 ! neuron maturation GO:0042551 21 14 0,000 0,05235783 0,0873897 ! regulation of S phase GO:0033261 18 14 0,000 0,05235783 0,08732633 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05235783 0,08726305 ! myotube differentiation GO:0014902 21 14 0,000 0,05235783 0,08719986 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,05235783 0,08713676 ! inositol metabolic process GO:0006020 20 14 0,000 0,05235783 0,08707376 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05235783 0,08701084 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05235783 0,08694802 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05235783 0,08688529 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05235783 0,08682264 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05235783 0,08676009 ! response to cAMP GO:0051591 19 14 0,000 0,05235783 0,08669763 ! limbic system development GO:0021761 25 14 0,000 0,05235783 0,08663526 ! startle response GO:0001964 21 14 0,000 0,05235783 0,08657298 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,05235783 0,08651078 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05235783 0,08644868 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05235783 0,08638666 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05235783 0,08632474 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,05235783 0,0862629 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05235783 0,08620115 ! glycine metabolic process GO:0006544 22 14 0,000 0,05235783 0,08613949 ! pituitary gland development GO:0021983 23 14 0,000 0,05235783 0,08607792 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05235783 0,08601643 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05235783 0,08595504 ! regulation of heart rate GO:0002027 23 14 0,000 0,05235783 0,08589373 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05235783 0,08583251 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05235783 0,08577137 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05235783 0,08571033 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05235783 0,08564937 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05235783 0,08558849 ! axon cargo transport GO:0008088 27 14 0,000 0,05235783 0,0855277 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05235783 0,085467 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05235783 0,08540639 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05235783 0,08534586 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05235783 0,08528542 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05235783 0,08522506 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05235783 0,08516479 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05235783 0,0851046 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05235783 0,0850445 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05235783 0,08498448 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05235783 0,08492455 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05235783 0,0848647 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05235783 0,08480494 ! muscle maintenance GO:0046716 19 14 0,000 0,05235783 0,08474526 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05235783 0,08468566 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05235783 0,08462615 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05235783 0,08456672 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05235783 0,08450737 ! cell killing GO:0001906 20 14 0,000 0,05235783 0,08444811 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05235783 0,08438893 ! cilium assembly GO:0042384 20 14 0,000 0,05235783 0,08432984 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05235783 0,08427082 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,05240728 0,08429143 ! in utero embryonic development GO:0001701 147 96 1,000 0,05240728 0,08423252 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,05240728 0,0841737 ! protein maturation GO:0051604 129 96 1,000 0,05240728 0,08411496 ! extracellular structure organization GO:0043062 156 99 1,000 0,05534897 0,08877451 ! protein import GO:0017038 156 99 1,000 0,05534897 0,08871264 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,05534897 0,08865086 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05599259 0,08961932 ! metencephalon development GO:0022037 19 15 0,000 0,05599259 0,089557 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05599259 0,08949476 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05599259 0,08943261 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05599259 0,08937055 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05599259 0,08930857 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05599259 0,08924668 ! lipid phosphorylation GO:0046834 23 15 0,000 0,05599259 0,08918488 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05599259 0,08912316 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05599259 0,08906152 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05599259 0,08899997 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05599259 0,08893851 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05599259 0,08887713 ! adult walking behavior GO:0007628 25 15 0,000 0,05599259 0,08881584 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05599259 0,08875463 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05599259 0,0886935 ! myoblast differentiation GO:0045445 27 15 0,000 0,05599259 0,08863246 ! centrosome cycle GO:0007098 16 15 0,000 0,05599259 0,0885715 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05599259 0,08851063 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05599259 0,08844984 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05599259 0,08838913 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05599259 0,08832851 ! cerebral cortex development GO:0021987 29 15 0,000 0,05599259 0,08826797 ! response to osmotic stress GO:0006970 22 15 0,000 0,05599259 0,08820751 ! vesicle coating GO:0006901 25 15 0,000 0,05599259 0,08814713 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05599259 0,08808684 ! DNA integration GO:0015074 22 15 0,000 0,05599259 0,08802663 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05599259 0,0879665 ! peptide secretion GO:0002790 27 15 0,000 0,05599259 0,08790646 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05599259 0,08784649 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05599259 0,08778661 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05599259 0,08772681 ! neuron recognition GO:0008038 22 15 0,000 0,05599259 0,08766709 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05599259 0,08760746 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05599259 0,0875479 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05599259 0,08748842 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05599259 0,08742903 ! biomineral formation GO:0031214 18 15 0,000 0,05599259 0,08736972 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05599259 0,08731048 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05599259 0,08725133 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05599259 0,08719226 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05599259 0,08713326 ! organic cation transport GO:0015695 19 15 0,000 0,05599259 0,08707435 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05599259 0,08701551 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05599259 0,08695676 ! defense response to virus GO:0051607 27 15 0,000 0,05599259 0,08689808 ! peptide hormone processing GO:0016486 19 15 0,000 0,05599259 0,08683949 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05599259 0,08678097 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,05634231 0,08726418 ! protein localization in organelle GO:0033365 161 100 1,000 0,05634231 0,08720546 ! protein secretion GO:0009306 27 16 0,000 0,05961362 0,09220667 ! hormone secretion GO:0046879 25 16 0,000 0,05961362 0,09214471 ! bone remodeling GO:0046849 24 16 0,000 0,05961362 0,09208282 ! endothelial cell migration GO:0043542 22 16 0,000 0,05961362 0,09202102 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05961362 0,09195931 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05961362 0,09189767 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05961362 0,09183612 ! glial cell development GO:0021782 24 16 0,000 0,05961362 0,09177465 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05961362 0,09171326 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05961362 0,09165196 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05961362 0,09159073 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05961362 0,09152959 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05961362 0,09146853 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05961362 0,09140755 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05961362 0,09134665 ! fructose metabolic process GO:0006000 20 16 0,000 0,05961362 0,09128584 ! regulation of protein binding GO:0043393 27 16 0,000 0,05961362 0,0912251 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05961362 0,09116445 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05961362 0,09110387 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05961362 0,09104338 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05961362 0,09098296 ! DNA replication initiation GO:0006270 25 16 0,000 0,05961362 0,09092263 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05961362 0,09086238 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05961362 0,0908022 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05961362 0,09074211 ! diencephalon development GO:0021536 25 16 0,000 0,05961362 0,09068209 ! oogenesis GO:0048477 23 16 0,000 0,05961362 0,09062216 ! neural crest cell migration GO:0001755 24 16 0,000 0,05961362 0,0905623 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05961362 0,09050253 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05961362 0,09044283 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05961362 0,09038321 ! steroid catabolic process GO:0006706 22 16 0,000 0,05961362 0,09032367 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05961362 0,0902642 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05961362 0,09020482 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05961362 0,09014551 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05961362 0,09008628 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05961362 0,09002713 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05961362 0,08996806 ! nerve development GO:0021675 18 16 0,000 0,05961362 0,08990907 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05961362 0,08985015 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05961362 0,08979131 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06322096 0,09516245 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,06322096 0,09510021 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06322096 0,09503805 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,06322096 0,09497598 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06322096 0,09491398 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06322096 0,09485207 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06322096 0,09479023 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06322096 0,09472848 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06322096 0,09466681 ! signal complex assembly GO:0007172 29 17 0,000 0,06322096 0,09460522 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06322096 0,09454371 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06322096 0,09448227 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06322096 0,09442092 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,06322096 0,09435965 ! keratinization GO:0031424 17 17 0,000 0,06322096 0,09429846 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06322096 0,09423734 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06322096 0,09417631 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06322096 0,09411535 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,06322096 0,09405448 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06322096 0,09399368 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06322096 0,09393296 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06322096 0,09387232 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,06322096 0,09381175 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06322096 0,09375127 ! membrane budding GO:0006900 29 17 0,000 0,06322096 0,09369086 ! heme metabolic process GO:0042168 27 17 0,000 0,06322096 0,09363053 ! actin filament bundle formation GO:0051017 26 17 0,000 0,06322096 0,09357028 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,06322096 0,09351011 ! body fluid secretion GO:0007589 27 17 0,000 0,06322096 0,09345001 ! stem cell differentiation GO:0048863 36 17 0,000 0,06322096 0,09338999 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06322096 0,09333005 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06322096 0,09327019 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06322096 0,0932104 ! sensory perception of pain GO:0019233 23 17 0,000 0,06322096 0,09315068 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,06322096 0,09309105 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06322096 0,09303149 ! synaptogenesis GO:0007416 24 17 0,000 0,06322096 0,09297201 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,06322096 0,0929126 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06322096 0,09285327 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06322096 0,09279401 ! cell-cell junction organization GO:0045216 25 17 0,000 0,06322096 0,09273483 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,06322096 0,09267573 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06322096 0,0926167 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,06322096 0,09255775 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06322096 0,09249887 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06322096 0,09244006 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06681468 0,09763263 ! positive regulation of translation GO:0045727 28 18 0,000 0,06681468 0,09757064 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06681468 0,09750873 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06681468 0,0974469 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06681468 0,09738514 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06681468 0,09732347 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06681468 0,09726187 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06681468 0,09720035 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06681468 0,09713891 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06681468 0,09707755 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06681468 0,09701626 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06681468 0,09695505 ! pancreas development GO:0031016 26 18 0,000 0,06681468 0,09689392 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06681468 0,09683287 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06681468 0,09677189 ! response to retinoic acid GO:0032526 25 18 0,000 0,06681468 0,09671099 ! pigmentation during development GO:0048066 31 18 0,000 0,06681468 0,09665016 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06681468 0,09658941 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06681468 0,09652874 ! fucose metabolic process GO:0006004 26 18 0,000 0,06681468 0,09646815 ! response to fungus GO:0009620 19 18 0,000 0,06681468 0,09640763 ! peptide cross-linking GO:0018149 31 18 0,000 0,06681468 0,09634718 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06681468 0,09628682 ! heart process GO:0003015 27 18 0,000 0,06681468 0,09622652 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06681468 0,09616631 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06681468 0,09610617 ! visual learning GO:0008542 35 18 0,000 0,06681468 0,0960461 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06681468 0,09598611 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06681468 0,09592619 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06681468 0,09586635 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06681468 0,09580658 ! vitamin transport GO:0051180 24 18 0,000 0,06681468 0,09574689 ! hormone transport GO:0009914 27 18 0,000 0,06681468 0,09568727 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06681468 0,09562773 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06681468 0,09556826 ! cell-cell recognition GO:0009988 20 18 0,000 0,06681468 0,09550886 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06681468 0,09544954 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06681468 0,09539029 ! regulation of glucose import GO:0046324 21 18 0,000 0,06681468 0,09533112 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06681468 0,09527201 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06681468 0,09521299 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,07039481 0,10025267 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,07039481 0,10019063 ! positive regulation of ossification GO:0045778 30 19 0,000 0,07039481 0,10012867 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,07039481 0,10006679 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,07039481 0,10000498 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,07039481 0,09994325 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,07039481 0,09988159 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,07039481 0,09982001 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,07039481 0,09975851 ! regeneration GO:0031099 32 19 0,000 0,07039481 0,09969708 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,07039481 0,09963573 ! response to alkaloid GO:0043279 32 19 0,000 0,07039481 0,09957445 ! sensory perception of taste GO:0050909 23 19 0,000 0,07039481 0,09951325 ! smooth muscle contraction GO:0006939 36 19 0,000 0,07039481 0,09945213 ! peroxisome organization GO:0007031 29 19 0,000 0,07039481 0,09939108 ! digestive system process GO:0022600 30 19 0,000 0,07039481 0,0993301 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,07039481 0,0992692 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,07039481 0,09920837 ! response to vitamin A GO:0033189 26 19 0,000 0,07039481 0,09914762 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,07039481 0,09908694 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,07039481 0,09902634 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,07039481 0,09896581 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,07039481 0,09890535 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,07039481 0,09884497 ! plasma membrane fusion GO:0045026 23 19 0,000 0,07039481 0,09878466 ! cytolysis GO:0019835 20 19 0,000 0,07039481 0,09872443 ! renal system process GO:0003014 35 19 0,000 0,07039481 0,09866427 ! vasodilation GO:0042311 33 19 0,000 0,07039481 0,09860418 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,07039481 0,09854416 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,07039481 0,09848422 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,07039481 0,09842435 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,07039481 0,09836456 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,07039481 0,09830483 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,07039481 0,09824518 ! sarcomere organization GO:0045214 23 19 0,000 0,07039481 0,0981856 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,07039481 0,0981261 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,07039481 0,09806666 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,07039481 0,0980073 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,07039481 0,09794801 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,07039481 0,09788879 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,07039481 0,09782964 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,07039481 0,09777057 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,07039481 0,09771156 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07396141 0,10260027 ! iron ion transport GO:0006826 37 20 0,000 0,07396141 0,10253842 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,07396141 0,10247665 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07396141 0,10241496 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07396141 0,10235333 ! response to vitamin GO:0033273 29 20 0,000 0,07396141 0,10229179 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07396141 0,10223031 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,07396141 0,10216891 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07396141 0,10210759 ! spinal cord development GO:0021510 31 20 0,000 0,07396141 0,10204634 ! response to ethanol GO:0045471 37 20 0,000 0,07396141 0,10198516 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07396141 0,10192405 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07396141 0,10186302 ! chromosome condensation GO:0030261 31 20 0,000 0,07396141 0,10180206 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07396141 0,10174117 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,07396141 0,10168036 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07396141 0,10161962 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07396141 0,10155895 ! pallium development GO:0021543 38 20 0,000 0,07396141 0,10149835 ! DNA modification GO:0006304 28 20 0,000 0,07396141 0,10143783 ! collagen fibril organization GO:0030199 45 20 0,000 0,07396141 0,10137738 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,07396141 0,101317 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,07396141 0,10125669 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07396141 0,10119646 ! collagen catabolic process GO:0030574 25 20 0,000 0,07396141 0,10113629 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,07396141 0,1010762 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07396141 0,10101618 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07396141 0,10095623 ! alditol metabolic process GO:0019400 24 20 0,000 0,07396141 0,10089635 ! actin filament-based movement GO:0030048 34 20 0,000 0,07396141 0,10083654 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07751453 0,10561814 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07751453 0,10555561 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07751453 0,10549315 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07751453 0,10543076 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07751453 0,10536845 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07751453 0,10530621 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07751453 0,10524405 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07751453 0,10518196 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07751453 0,10511994 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07751453 0,105058 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07751453 0,10499612 ! vesicle docking GO:0048278 27 21 0,000 0,07751453 0,10493433 ! phototransduction GO:0007602 25 21 0,000 0,07751453 0,1048726 ! dendrite development GO:0016358 35 21 0,000 0,07751453 0,10481095 ! visual behavior GO:0007632 39 21 0,000 0,07751453 0,10474937 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07751453 0,10468786 ! ovarian follicle development GO:0001541 30 21 0,000 0,07751453 0,10462642 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07751453 0,10456506 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07751453 0,10450376 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07751453 0,10444254 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07751453 0,10438139 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07751453 0,10432032 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07751453 0,10425931 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07751453 0,10419837 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07751453 0,10413751 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07751453 0,10407672 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07751453 0,104016 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07751453 0,10395535 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07751453 0,10389477 ! fatty acid transport GO:0015908 30 21 0,000 0,07751453 0,10383426 ! immunoglobulin production GO:0002377 33 21 0,000 0,07751453 0,10377382 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07751453 0,10371345 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07751453 0,10365315 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07751453 0,10359292 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07751453 0,10353276 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07751453 0,10347268 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07751453 0,10341266 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07751453 0,10335271 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07751453 0,10329283 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07751453 0,10323302 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07751453 0,10317328 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07751453 0,1031136 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07751453 0,103054 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07751453 0,10299447 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,08105422 0,10763551 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,08105422 0,1075734 ! viral genome replication GO:0019079 29 22 0,000 0,08105422 0,10751136 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,08105422 0,1074494 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,08105422 0,1073875 ! molting cycle process GO:0022404 40 22 0,000 0,08105422 0,10732568 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,08105422 0,10726393 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,08105422 0,10720225 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,08105422 0,10714064 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,08105422 0,1070791 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,08105422 0,10701763 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,08105422 0,10695623 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,08105422 0,1068949 ! lysosome organization GO:0007040 37 22 0,000 0,08105422 0,10683364 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,08105422 0,10677245 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,08105422 0,10671134 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,08105422 0,10665029 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,08105422 0,10658931 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,08105422 0,1065284 ! membrane depolarization GO:0051899 35 22 0,000 0,08105422 0,10646756 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,08105422 0,1064068 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,08105422 0,1063461 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,08105422 0,10628547 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,08105422 0,1062249 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,08105422 0,10616441 ! blastocyst development GO:0001824 37 22 0,000 0,08105422 0,10610399 ! neural tube closure GO:0001843 33 22 0,000 0,08105422 0,10604363 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,08458053 0,11059421 ! neuron fate commitment GO:0048663 32 23 0,000 0,08458053 0,11053137 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08458053 0,11046861 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,08458053 0,11040591 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,08458053 0,11034329 ! vesicle targeting GO:0006903 32 23 0,000 0,08458053 0,11028074 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,08458053 0,11021825 ! osteoblast differentiation GO:0001649 40 23 0,000 0,08458053 0,11015584 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08458053 0,1100935 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08458053 0,11003123 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,08458053 0,10996903 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08458053 0,1099069 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,08458053 0,10984484 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08458053 0,10978285 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,08458053 0,10972094 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08458053 0,10965909 ! cell fate determination GO:0001709 45 23 0,000 0,08458053 0,10959731 ! pentose metabolic process GO:0019321 31 23 0,000 0,08458053 0,1095356 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08458053 0,10947396 ! spermatid development GO:0007286 33 23 0,000 0,08458053 0,10941238 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08458053 0,10935088 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08458053 0,10928945 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08458053 0,10922808 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,08458053 0,10916679 ! telomere organization GO:0032200 32 23 0,000 0,08458053 0,10910556 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,08458053 0,1090444 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,08458053 0,10898332 ! regulation of amine transport GO:0051952 38 23 0,000 0,08458053 0,10892229 ! liver development GO:0001889 40 23 0,000 0,08458053 0,10886134 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08809351 0,11331939 ! initiation of viral infection GO:0019059 42 24 0,000 0,08809351 0,11325605 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08809351 0,11319278 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08809351 0,11312958 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08809351 0,11306645 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08809351 0,11300339 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,08809351 0,1129404 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08809351 0,11287748 ! sperm motility GO:0030317 27 24 0,000 0,08809351 0,11281463 ! vacuole organization GO:0007033 39 24 0,000 0,08809351 0,11275185 ! receptor metabolic process GO:0043112 37 24 0,000 0,08809351 0,11268914 ! neural crest cell development GO:0014032 39 24 0,000 0,08809351 0,1126265 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08809351 0,11256393 ! primary neural tube formation GO:0014020 35 24 0,000 0,08809351 0,11250143 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08809351 0,112439 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08809351 0,11237663 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,08809351 0,11231434 ! glutathione metabolic process GO:0006749 29 24 0,000 0,08809351 0,11225212 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08809351 0,11218996 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,09159321 0,11658239 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,09159321 0,11651791 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,09159321 0,1164535 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,09159321 0,11638916 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,09159321 0,11632489 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,09159321 0,11626069 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,09159321 0,11619657 ! peptide transport GO:0015833 43 25 0,000 0,09159321 0,11613251 ! male gonad development GO:0008584 33 25 0,000 0,09159321 0,11606853 ! iron ion homeostasis GO:0055072 39 25 0,000 0,09159321 0,11600461 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,09159321 0,11594077 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,09159321 0,115877 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,09159321 0,11581329 ! phospholipid transport GO:0015914 35 25 0,000 0,09159321 0,11574966 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,09159321 0,11568609 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,09159321 0,1156226 ! detection of light stimulus GO:0009583 30 25 0,000 0,09159321 0,11555918 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,09159321 0,11549582 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,09159321 0,11543254 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,09507967 0,11976082 ! circadian rhythm GO:0007623 42 26 0,000 0,09507967 0,11969527 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,09507967 0,11962979 ! post-embryonic development GO:0009791 42 26 0,000 0,09507967 0,11956438 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,09507967 0,11949904 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,09507967 0,11943378 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,09507967 0,11936859 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,09507967 0,11930346 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,09507967 0,11923841 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,09507967 0,11917343 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,09507967 0,11910852 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,09507967 0,11904369 ! regulation of coagulation GO:0050818 39 26 0,000 0,09507967 0,11897892 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09855296 0,12325819 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09855296 0,1231912 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09855296 0,12312428 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09855296 0,12305744 ! membrane docking GO:0022406 39 27 0,000 0,09855296 0,12299067 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09855296 0,12292397 ! catechol metabolic process GO:0009712 43 27 0,000 0,09855296 0,12285735 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09855296 0,12279079 ! acute-phase response GO:0006953 42 27 0,000 0,09855296 0,12272431 ! myofibril assembly GO:0030239 36 27 0,000 0,09855296 0,1226579 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09855296 0,12259157 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09855296 0,1225253 ! natural killer cell activation GO:0030101 35 27 0,000 0,09855296 0,12245911 ! lipid oxidation GO:0034440 38 27 0,000 0,09855296 0,12239298 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09855296 0,12232693 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09855296 0,12226095 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09855296 0,12219504 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09855296 0,12212921 ! gene silencing GO:0016458 41 27 0,000 0,09855296 0,12206344 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,10201311 0,12628103 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,10201311 0,1262131 ! phenol metabolic process GO:0018958 44 28 0,000 0,10201311 0,12614525 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,10201311 0,12607746 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,10201311 0,12600975 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,10201311 0,12594211 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,10201311 0,12587455 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,10201311 0,12580705 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,10201311 0,12573963 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,10201311 0,12567228 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,10201311 0,12560501 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,10201311 0,1255378 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,10201311 0,12547067 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,10201311 0,12540361 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,10201311 0,12533662 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,10201311 0,1252697 ! mesoderm formation GO:0001707 46 28 0,000 0,10201311 0,12520286 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,10201311 0,12513608 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,10201311 0,12506938 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,10201311 0,12500275 ! BMP signaling pathway GO:0030509 40 28 0,000 0,10201311 0,12493619 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,10201311 0,12486969 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,10201311 0,12480327 ! neural tube formation GO:0001841 41 28 0,000 0,10201311 0,12473693 ! placenta development GO:0001890 37 28 0,000 0,10201311 0,12467065 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,10546018 0,12881488 ! regulation of innate immune response GO:0045088 38 29 0,000 0,10546018 0,1287465 ! ovulation cycle process GO:0022602 41 29 0,000 0,10546018 0,1286782 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,10546018 0,12860997 ! protein targeting to membrane GO:0006612 53 29 0,000 0,10546018 0,12854182 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,10546018 0,12847374 ! mismatch repair GO:0006298 34 29 0,000 0,10546018 0,12840572 ! muscle cell development GO:0055001 38 29 0,000 0,10546018 0,12833778 ! formation of primary germ layer GO:0001704 48 29 0,000 0,10546018 0,12826992 ! telencephalon development GO:0021537 52 29 0,000 0,10546018 0,12820212 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,10546018 0,1281344 ! eye morphogenesis GO:0048592 51 29 0,000 0,10546018 0,12806674 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,10546018 0,12799916 ! tissue homeostasis GO:0001894 42 29 0,000 0,10546018 0,12793165 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,10889421 0,13202777 ! collagen metabolic process GO:0032963 40 30 0,000 0,10889421 0,13195821 ! organic anion transport GO:0015711 51 30 0,000 0,10889421 0,13188872 ! cholesterol transport GO:0030301 46 30 0,000 0,10889421 0,13181931 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,10889421 0,13174997 ! spliceosome assembly GO:0000245 49 30 0,000 0,10889421 0,1316807 ! spindle organization GO:0007051 37 30 0,000 0,10889421 0,1316115 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,10889421 0,13154238 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,10889421 0,13147333 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,10889421 0,13140435 ! ceramide metabolic process GO:0006672 43 30 0,000 0,10889421 0,13133544 ! ovulation cycle GO:0042698 43 30 0,000 0,10889421 0,13126661 ! hindbrain development GO:0030902 45 30 0,000 0,10889421 0,13119785 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,10889421 0,13112916 ! adult locomotory behavior GO:0008344 47 30 0,000 0,10889421 0,13106054 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,10889421 0,13099199 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,10889421 0,13092352 ! response to heat GO:0009408 41 30 0,000 0,10889421 0,13085511 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,10889421 0,13078678 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,10889421 0,13071852 ! negative regulation of secretion GO:0051048 49 31 0,000 0,11231526 0,13475487 ! glial cell differentiation GO:0010001 55 31 0,000 0,11231526 0,13468461 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,11231526 0,13461443 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,11231526 0,13454432 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,11231526 0,13447428 ! odontogenesis GO:0042476 50 31 0,000 0,11231526 0,13440431 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,11231526 0,13433442 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,11231526 0,1342646 ! metanephros development GO:0001656 58 31 0,000 0,11231526 0,13419485 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,11231526 0,13412518 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,11231526 0,13405557 ! cell fate specification GO:0001708 37 31 0,000 0,11231526 0,13398604 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,11231526 0,13391658 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,11231526 0,1338472 ! regulation of muscle development GO:0048634 48 32 0,000 0,11572336 0,13783725 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,11572336 0,13776591 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,11572336 0,13769464 ! meiosis I GO:0007127 52 32 0,000 0,11572336 0,13762344 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,11572336 0,13755232 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,11572336 0,13748127 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,11572336 0,13741029 GO:0006639|acylglycerol metabolic process, ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,11572336 0,13733939 ! cytokine production GO:0001816 44 32 0,000 0,11572336 0,13726856 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,11572336 0,1371978 ! vesicle localization GO:0051648 47 32 0,000 0,11572336 0,13712712 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,11911858 0,14107762 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,11911858 0,14100501 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11911858 0,14093248 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11911858 0,14086002 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,11911858 0,14078763 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11911858 0,14071532 ! ear morphogenesis GO:0042471 42 33 0,000 0,11911858 0,14064309 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11911858 0,14057093 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11911858 0,14049884 ! nucleus organization GO:0006997 49 33 0,000 0,11911858 0,14042683 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11911858 0,14035489 ! female gonad development GO:0008585 49 33 0,000 0,11911858 0,14028302 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11911858 0,14021123 ! lipid homeostasis GO:0055088 55 33 0,000 0,11911858 0,14013951 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11911858 0,14006786 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11911858 0,13999629 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11911858 0,13992479 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,11911858 0,13985336 ! cytokinesis GO:0000910 52 33 0,000 0,11911858 0,13978201 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11911858 0,13971073 ! mRNA catabolic process GO:0006402 48 34 0,000 0,12250096 0,14360459 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,12250096 0,14353143 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,12250096 0,14345835 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,12250096 0,14338534 ! feeding behavior GO:0007631 45 34 0,000 0,12250096 0,14331241 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,12250096 0,14323955 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,12250096 0,14316677 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,12250096 0,14309406 ! neuron migration GO:0001764 46 34 0,000 0,12250096 0,14302142 ! female gamete generation GO:0007292 43 34 0,000 0,12250096 0,14294886 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,12250096 0,14287637 ! polyol metabolic process GO:0019751 44 34 0,000 0,12250096 0,14280395 ! aerobic respiration GO:0009060 47 34 0,000 0,12250096 0,14273161 ! embryonic organ development GO:0048568 45 34 0,000 0,12250096 0,14265934 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,12250096 0,14258714 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,12587054 0,14643512 ! Notch signaling pathway GO:0007219 56 35 0,000 0,12587054 0,14636109 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,12587054 0,14628713 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,12587054 0,14621325 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,12587054 0,14613944 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,12587054 0,14606571 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,12587054 0,14599205 ! glycogen metabolic process GO:0005977 48 35 0,000 0,12587054 0,14591846 ! pigment metabolic process GO:0042440 61 35 0,000 0,12587054 0,14584495 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12922737 0,14965909 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,12922737 0,14958377 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12922737 0,14950853 ! organic ether metabolic process GO:0018904 46 36 0,000 0,12922737 0,14943336 ! neural tube development GO:0021915 50 36 0,000 0,12922737 0,14935827 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12922737 0,14928325 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12922737 0,14920831 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,12922737 0,14913344 ! glucan metabolic process GO:0044042 49 36 0,000 0,12922737 0,14905865 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,1325715 0,15283933 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,1325715 0,15276275 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,1325715 0,15268626 ! learning GO:0007612 67 37 0,000 0,1325715 0,15260984 ! ion transmembrane transport GO:0034220 56 37 0,000 0,1325715 0,1525335 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,1325715 0,15245723 ! regulation of protein secretion GO:0050708 51 37 0,000 0,1325715 0,15238104 ! amino acid activation GO:0043038 52 37 0,000 0,1325715 0,15230492 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,1325715 0,15222889 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,13590299 0,15597648 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,13590299 0,15589869 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,13590299 0,15582097 ! phagocytosis GO:0006909 60 38 0,000 0,13590299 0,15574333 ! mesenchymal cell development GO:0014031 64 38 0,000 0,13590299 0,15566577 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,13590299 0,15558829 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,13922186 0,1593086 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13922186 0,15922938 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,13922186 0,15915024 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13922186 0,15907118 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,13922186 0,1589922 ! male sex differentiation GO:0046661 53 39 0,000 0,13922186 0,15891329 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13922186 0,15883447 ! chromatin remodeling GO:0006338 68 39 0,000 0,13922186 0,15875572 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13922186 0,15867705 ! developmental growth GO:0048589 62 39 0,000 0,13922186 0,15859846 ! cell growth GO:0016049 61 39 0,000 0,13922186 0,15851994 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,14252818 0,16220427 ! response to calcium ion GO:0051592 58 40 0,000 0,14252818 0,16212405 ! regulation of tube size GO:0035150 60 40 0,000 0,14252818 0,16204391 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,14252818 0,16196384 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,14252818 0,16188386 ! peptide metabolic process GO:0006518 56 40 0,000 0,14252818 0,16180396 ! inner ear development GO:0048839 57 40 0,000 0,14252818 0,16172414 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,14252818 0,16164439 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! JAK-STAT cascade GO:0007259 53 40 0,000 0,14252818 0,16156472 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,14582199 0,16521704 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,14582199 0,16513569 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,14582199 0,16505442 ! glucose transport GO:0015758 52 41 0,000 0,14582199 0,16497323 ! endosome transport GO:0016197 71 41 0,000 0,14582199 0,16489212 ! striated muscle contraction GO:0006941 62 41 0,000 0,14582199 0,1648111 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,14582199 0,16473015 ! biopolymer methylation GO:0043414 62 41 0,000 0,14582199 0,16464928 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14910334 0,16827168 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,14910334 0,16818915 ! cellular component disassembly GO:0022411 64 42 0,000 0,14910334 0,1681067 ! hexose transport GO:0008645 54 42 0,000 0,14910334 0,16802434 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,14910334 0,16794205 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14910334 0,16785985 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,14910334 0,16777773 ! excretion GO:0007588 63 42 0,000 0,14910334 0,16769568 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14910334 0,16761372 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,14910334 0,16753184 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,14910334 0,16745004 ! leukocyte migration GO:0050900 60 43 0,000 0,15237226 0,17103768 ! neuromuscular process GO:0050905 79 43 0,000 0,15237226 0,17095425 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,15237226 0,17087089 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,15237226 0,17078762 ! vesicle organization GO:0016050 79 43 0,000 0,15237226 0,17070443 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,15237226 0,17062133 ! methylation GO:0032259 64 43 0,000 0,15237226 0,1705383 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,15562882 0,17409839 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,15562882 0,17401375 ! glycolysis GO:0006096 53 44 0,000 0,15562882 0,17392919 ! regulation of ion transport GO:0043269 57 44 0,000 0,15562882 0,17384472 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,15562882 0,17376033 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,15562882 0,17367602 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,15562882 0,17359179 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,15562882 0,17350765 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,15562882 0,17342359 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,15562882 0,1733396 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,15562882 0,1732557 ! RNA catabolic process GO:0006401 64 45 0,000 0,15887305 0,17678181 ! positive regulation of defense response GO:0031349 59 45 0,000 0,15887305 0,17669633 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,15887305 0,17661093 ! cell recognition GO:0008037 58 45 0,000 0,15887305 0,17652561 ! cell maturation GO:0048469 60 45 0,000 0,15887305 0,17644037 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,162105 0,17994281 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,162105 0,179856 ! cell redox homeostasis GO:0045454 63 46 0,000 0,162105 0,17976928 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,162105 0,17968265 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,162105 0,17959609 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,16532471 0,18307503 ! viral infectious cycle GO:0019058 71 47 0,000 0,16532471 0,18298693 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,16532471 0,18289891 ! endocrine system development GO:0035270 83 47 0,000 0,16532471 0,18281098 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,16532471 0,18272313 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,16532471 0,18263537 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,16532471 0,18254769 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,16532471 0,1824601 ! chloride transport GO:0006821 67 48 0,000 0,16853224 0,18591086 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,16853224 0,18582174 ! response to temperature stimulus GO:0009266 62 48 0,000 0,16853224 0,1857327 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,16853224 0,18564375 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,16853224 0,18555488 ! gastrulation GO:0007369 73 48 0,000 0,16853224 0,1854661 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,16853224 0,1853774 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,16853224 0,18528879 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,16853224 0,18520026 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,16853224 0,18511182 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,17172762 0,18853152 ! sensory perception of smell GO:0007608 61 49 0,000 0,17172762 0,18844157 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,17172762 0,18835171 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,17172762 0,18826193 ! RNA elongation GO:0006354 62 49 0,000 0,17172762 0,18817224 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,17172762 0,18808264 ! germ cell development GO:0007281 68 49 0,000 0,17172762 0,18799312 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,17172762 0,18790368 ! cartilage development GO:0051216 70 49 0,000 0,17172762 0,18781433 ! regulation of actin filament length GO:0030832 72 50 0,000 0,17491091 0,19120489 ! ear development GO:0043583 72 50 0,000 0,17491091 0,19111406 ! membrane fusion GO:0006944 80 50 0,000 0,17491091 0,19102331 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,17491091 0,19093265 ! lipid modification GO:0030258 73 50 0,000 0,17491091 0,19084208 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,17491091 0,19075159 ! proton transport GO:0015992 75 50 0,000 0,17491091 0,19066118 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,17491091 0,19057087 ! positive regulation of secretion GO:0051047 71 51 0,000 0,17808215 0,19393416 ! hydrogen transport GO:0006818 77 51 0,000 0,17808215 0,19384238 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,17808215 0,19375068 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,17808215 0,19365907 ! adult behavior GO:0030534 80 51 0,000 0,17808215 0,19356755 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,17808215 0,19347612 ! transition metal ion transport GO:0000041 74 52 0,000 0,18124137 0,19681547 ! regulation of cellular component size GO:0032535 74 52 0,000 0,18124137 0,19672259 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,18124137 0,19662979 ! establishment of organelle localization GO:0051656 85 52 0,000 0,18124137 0,19653709 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,18438864 0,19985574 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,18438864 0,1997616 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,18438864 0,19966755 ! kidney development GO:0001822 90 53 0,000 0,18438864 0,19957359 ! single fertilization GO:0007338 59 53 0,000 0,18438864 0,19947971 ! cell projection assembly GO:0030031 76 53 0,000 0,18438864 0,19938593 ! amino acid transport GO:0006865 84 54 0,000 0,18752399 0,202681 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,18752399 0,2025858 ! glucose catabolic process GO:0006007 66 54 0,000 0,18752399 0,20249069 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,18752399 0,20239567 ! DNA catabolic process GO:0006308 67 54 0,000 0,18752399 0,20230074 ! detection of external stimulus GO:0009581 66 54 0,000 0,18752399 0,20220589 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,18752399 0,20211114 ! exocytosis GO:0006887 74 55 0,000 0,19064746 0,20538134 ! mesoderm development GO:0007498 76 55 0,000 0,19064746 0,20528519 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,19064746 0,20518912 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,19064746 0,20509315 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,1937591 0,20834312 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,1937591 0,20824577 ! carbohydrate transport GO:0008643 74 57 0,000 0,19685896 0,21147857 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,19685896 0,21137984 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,19685896 0,2112812 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,19685896 0,21118266 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,19685896 0,2110842 ! camera-type eye development GO:0043010 88 57 0,000 0,19685896 0,21098584 ! secondary metabolic process GO:0019748 84 57 0,000 0,19685896 0,21088757 ! developmental maturation GO:0021700 75 57 0,000 0,19685896 0,21078939 ! gonad development GO:0008406 79 57 0,000 0,19685896 0,21069131 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,19994708 0,21389688 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,19994708 0,21379744 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,2030235 0,21698608 ! actin filament organization GO:0007015 95 59 0,000 0,2030235 0,2168853 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,2030235 0,21678461 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,2030235 0,21668401 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,20608827 0,21985298 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,20608827 0,21975105 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,20608827 0,21964922 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,20608827 0,21954748 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,20608827 0,21944584 ! regulation of heart contraction GO:0008016 91 60 0,000 0,20608827 0,21934429 ! fertilization GO:0009566 68 60 0,000 0,20608827 0,21924284 ! meiosis GO:0007126 96 61 0,000 0,20914142 0,22238801 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,20914142 0,22228525 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,20914142 0,22218257 ! urogenital system development GO:0001655 101 61 0,000 0,20914142 0,22208 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,20914142 0,22197751 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,20914142 0,22187513 ! extracellular matrix organization GO:0030198 103 61 0,000 0,20914142 0,22177283 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,20914142 0,22167063 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,20914142 0,22156853 ! amine catabolic process GO:0009310 90 62 0,000 0,21218301 0,22468735 ! neurotransmitter transport GO:0006836 81 62 0,000 0,21218301 0,22458395 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,21218301 0,22448065 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,21218301 0,22437744 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,21218301 0,22427432 ! meiotic cell cycle GO:0051321 97 62 0,000 0,21218301 0,2241713 ! organelle localization GO:0051640 96 62 0,000 0,21218301 0,22406838 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,21521308 0,22716387 ! appendage morphogenesis GO:0035107 93 64 0,000 0,21823166 0,23024441 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,21823166 0,23013885 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,21823166 0,23003337 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,21823166 0,229928 ! hexose catabolic process GO:0019320 82 64 0,000 0,21823166 0,22982272 ! reproductive structure development GO:0048608 90 65 0,000 0,22123881 0,23288296 ! appendage development GO:0048736 94 65 0,000 0,22123881 0,23277642 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,22123881 0,23266999 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,22123881 0,23256365 ! defense response to bacterium GO:0042742 73 65 0,000 0,22123881 0,23245741 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,22123881 0,23235126 ! activation of immune response GO:0002253 83 65 0,000 0,22123881 0,23224521 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,22423456 0,23528261 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,22423456 0,23517533 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,22423456 0,23506813 ! regulation of immune effector process GO:0002697 101 66 0,000 0,22423456 0,23496104 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,22721896 0,23797978 ! acute inflammatory response GO:0002526 92 68 0,000 0,23019205 0,24098394 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,23019205 0,2408743 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,23019205 0,24076476 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,23019205 0,24065532 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,23019205 0,24054598 ! rhythmic process GO:0048511 105 68 0,000 0,23019205 0,24043674 ! inorganic anion transport GO:0015698 93 68 0,000 0,23019205 0,2403276 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,23315387 0,24330939 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,23315387 0,24319904 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,23315387 0,2430888 ! response to metal ion GO:0010038 103 70 0,000 0,23610446 0,24605358 ! eye development GO:0001654 111 70 0,000 0,23610446 0,24594215 ! amine transport GO:0015837 101 70 0,000 0,23610446 0,24583081 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,23610446 0,24571957 ! muscle cell differentiation GO:0042692 104 71 0,000 0,23904387 0,24866617 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,23904387 0,24855375 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,23904387 0,24844144 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,23904387 0,24832922 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,23904387 0,24821711 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,24197214 0,25114437 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,24197214 0,25103109 ! regulation of blood pressure GO:0008217 107 73 0,000 0,2448893 0,25394292 ! tube morphogenesis GO:0035239 118 73 0,000 0,2448893 0,25382848 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,2448893 0,25371414 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,2448893 0,25359991 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,24779541 0,2564939 ! digestion GO:0007586 97 74 0,000 0,24779541 0,25637852 ! blood coagulation GO:0007596 116 75 0,000 0,2506905 0,25925726 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,2506905 0,25914074 ! response to nutrient GO:0007584 104 75 0,000 0,2506905 0,25902433 ! regulation of ligase activity GO:0051340 114 75 0,000 0,2506905 0,25890801 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,2506905 0,25879181 ! amine biosynthetic process GO:0009309 97 76 0,000 0,25357461 0,26165169 ! response to unfolded protein GO:0006986 99 76 0,000 0,25357461 0,26153435 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,25644779 0,26437916 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,25644779 0,26426071 ! sex differentiation GO:0007548 105 77 0,000 0,25644779 0,26414237 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,25644779 0,26402413 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,25644779 0,263906 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,25644779 0,26378797 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,25931007 0,26661294 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,25931007 0,26649381 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,25931007 0,26637479 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,26216149 0,26918368 ! cellular respiration GO:0045333 107 79 0,000 0,26216149 0,26906356 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,26216149 0,26894355 ! regulation of lyase activity GO:0051339 133 79 0,000 0,26216149 0,26882365 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,26216149 0,26870385 ! alcohol catabolic process GO:0046164 104 80 0,000 0,26500211 0,27149436 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,26500211 0,27137348 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,26500211 0,27125271 ! forebrain development GO:0030900 131 80 0,000 0,26500211 0,27113205 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,26783195 0,2739055 ! hemostasis GO:0007599 125 81 0,000 0,26783195 0,27378377 ! mRNA transport GO:0051028 121 81 0,000 0,26783195 0,27366214 ! response to protein stimulus GO:0051789 111 81 0,000 0,26783195 0,27354062 ! regulation of neurological system process GO:0031644 122 81 0,000 0,26783195 0,27341921 ! vitamin metabolic process GO:0006766 103 81 0,000 0,26783195 0,2732979 ! detection of stimulus GO:0051606 108 82 0,000 0,27065105 0,27605207 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,27345946 0,27879289 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,27345946 0,27866937 ! regulation of defense response GO:0031347 117 84 0,000 0,27625722 0,28139576 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,27625722 0,28127119 ! sterol metabolic process GO:0016125 120 84 0,000 0,27625722 0,28114673 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,27904437 0,28385761 ! rRNA metabolic process GO:0016072 107 85 0,000 0,27904437 0,28373212 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,27904437 0,28360674 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,28182094 0,28630219 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,28458698 0,28898457 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,28458698 0,28885704 ! female pregnancy GO:0007565 130 87 0,000 0,28458698 0,28872962 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,28458698 0,28860232 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,28734252 0,29126831 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,28734252 0,29114 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,28734252 0,2910118 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,28734252 0,29088372 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,28734252 0,29075574 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,29008761 0,29340436 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,29008761 0,29327539 ! hormone metabolic process GO:0042445 121 90 0,000 0,29282228 0,29591004 ! RNA localization GO:0006403 135 91 0,000 0,29554658 0,29853189 ! ATP metabolic process GO:0046034 137 91 0,000 0,29554658 0,29840084 ! response to virus GO:0009615 122 91 0,000 0,29554658 0,29826991 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,29826053 0,30087685 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,29826053 0,30074494 ! positive regulation of immune response GO:0050778 121 92 0,000 0,29826053 0,30061315 ! DNA recombination GO:0006310 146 92 0,000 0,29826053 0,30048148 ! sulfur metabolic process GO:0006790 118 92 0,000 0,29826053 0,30034992 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,30096418 0,30293988 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,30096418 0,30280736 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,30096418 0,30267495 ! electron transport chain GO:0022900 123 94 0,000 0,30365758 0,30525019 ! response to oxidative stress GO:0006979 141 94 0,000 0,30365758 0,30511683 ! carboxylic acid transport GO:0046942 147 95 0,000 0,30634074 0,30767848 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,30901373 0,31022766 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,30901373 0,31009231 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,31167657 0,31262804 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,31167657 0,31249176 ! calcium ion transport GO:0006816 167 99 0,000 0,31697195 0,31766252 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,31960457 0,32016137 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,31960457 0,32002199 ! divalent metal ion transport GO:0070838 171 100 0,000 0,31960457 0,31988273 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,31960457 0,31974359 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,31960457 0,31960457