pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6202-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of translational initiation GO:0006446 82 53 6,000 3,94E-10 9,479E-07 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,676E-06 2,016E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,133E-05 9,087E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,149E-05 6,911E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,297E-05 6,242E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,361E-05 5,458E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,131E-05 7,326E-03 ! response to UV GO:0009411 104 53 3,000 2,623E-05 7,889E-03 ! aging GO:0007568 103 55 3,000 3,04E-05 8,127E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 3,266E-05 7,857E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,504E-05 7,663E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 3,504E-05 7,025E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 3,548E-05 6,567E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,548E-05 6,098E-03 ! cell aging GO:0007569 44 21 2,000 4,13E-05 6,624E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,293E-05 6,456E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,771E-05 6,752E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 5,473E-05 7,316E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 5,473E-05 6,931E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,539E-05 6,664E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 6,241E-05 7,15E-03 ! protein tetramerization GO:0051262 52 24 2,000 6,241E-05 6,825E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 7,075E-05 7,401E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 7,979E-05 7,999E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 8,794E-05 8,464E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 9,787E-05 9,057E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,02E-04 9,091E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,02E-04 8,767E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,02E-04 8,464E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 1,02E-04 8,182E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,02E-04 7,918E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,02E-04 7,671E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,02E-04 7,438E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,02E-04 7,22E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,02E-04 7,013E-03 ! translational initiation GO:0006413 65 29 2,000 1,114E-04 7,442E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,114E-04 7,241E-03 ! protein oligomerization GO:0051259 139 78 3,000 1,201E-04 7,607E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,262E-04 7,788E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,501E-04 9,029E-03 ! male sex determination GO:0030238 15 6 1,000 1,527E-04 8,962E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,527E-04 8,748E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,527E-04 8,545E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 1,967E-04 0,01075524 ! regulation of helicase activity GO:0051095 15 7 1,000 2,133E-04 0,01140688 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,133E-04 0,01115891 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 1,000 2,133E-04 0,01092148 ! mRNA stabilization GO:0048255 18 7 1,000 2,133E-04 0,01069395 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 2,133E-04 0,01047571 GO:0031958|corticosteroid receptor signaling pathway, ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 2,133E-04 0,0102662 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,133E-04 0,0100649 ! B cell lineage commitment GO:0002326 21 7 1,000 2,133E-04 9,871E-03 ! regulation of meiosis GO:0040020 12 7 1,000 2,133E-04 9,685E-03 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 1,000 2,133E-04 9,506E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,133E-04 9,333E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,133E-04 9,166E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,517E-04 0,01062635 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,572E-04 0,01066817 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,785E-04 0,01135808 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,839E-04 0,01138292 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,839E-04 0,01119632 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,839E-04 0,01101573 ! ER overload response GO:0006983 12 8 1,000 2,839E-04 0,01084088 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,839E-04 0,01067149 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,839E-04 0,01050731 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,839E-04 0,01034811 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,839E-04 0,01019366 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,839E-04 0,01004376 ! interphase GO:0051325 213 98 3,000 2,897E-04 0,01010042 ! cell cycle arrest GO:0007050 213 100 3,000 3,129E-04 0,0107547 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 3,394E-04 0,01150149 ! regulation of developmental growth GO:0048638 15 9 1,000 3,642E-04 0,01217038 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,642E-04 0,01200366 ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,642E-04 0,01184145 ! regulation of glycolysis GO:0006110 21 9 1,000 3,642E-04 0,01168356 ! keratinocyte proliferation GO:0043616 14 9 1,000 3,642E-04 0,01152983 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 3,642E-04 0,01138009 ! behavioral fear response GO:0001662 22 9 1,000 3,642E-04 0,01123419 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 3,642E-04 0,01109199 ! protein heterooligomerization GO:0051291 16 9 1,000 3,642E-04 0,01095334 ! B cell differentiation GO:0030183 107 44 2,000 3,897E-04 0,01157656 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 4,446E-04 0,01304603 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,446E-04 0,01288885 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,446E-04 0,01273541 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,543E-04 0,01285923 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,543E-04 0,0127097 ! lung alveolus development GO:0048286 26 10 1,000 4,543E-04 0,01256361 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,543E-04 0,01242084 ! regulation of bone resorption GO:0045124 25 10 1,000 4,543E-04 0,01228128 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 4,543E-04 0,01214483 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4,543E-04 0,01201137 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,543E-04 0,01188081 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 4,543E-04 0,01175306 ! localization within membrane GO:0051668 20 10 1,000 4,543E-04 0,01162802 ! positive regulation of cell cycle GO:0045787 89 48 2,000 5,043E-04 0,01277081 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 5,043E-04 0,01263778 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 5,541E-04 0,01374357 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,541E-04 0,01360333 ! blood vessel remodeling GO:0001974 29 11 1,000 5,541E-04 0,01346593 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 5,541E-04 0,01333127 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,541E-04 0,01319927 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,541E-04 0,01306987 ! regulation of leukocyte migration GO:0002685 26 11 1,000 5,541E-04 0,01294298 ! sequestering of metal ion GO:0051238 14 11 1,000 5,541E-04 0,01281853 ! regulation of embryonic development GO:0045995 27 11 1,000 5,541E-04 0,01269644 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 6,029E-04 0,01368486 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 2,000 6,383E-04 0,01435352 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,635E-04 0,01478143 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 6,635E-04 0,01464582 ! virus-host interaction GO:0019048 29 12 1,000 6,635E-04 0,01451268 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,635E-04 0,01438194 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 6,635E-04 0,01425353 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 6,635E-04 0,01412739 ! positive regulation of cell growth GO:0030307 22 12 1,000 6,635E-04 0,01400346 ! fear response GO:0042596 26 12 1,000 6,635E-04 0,01388169 ! regulation of phagocytosis GO:0050764 16 12 1,000 6,635E-04 0,01376202 ! histone acetylation GO:0016573 26 12 1,000 6,635E-04 0,0136444 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,635E-04 0,01352877 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 6,635E-04 0,01341508 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 6,635E-04 0,01330329 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 7,825E-04 0,01555942 ! pseudouridine synthesis GO:0001522 17 13 1,000 7,825E-04 0,01543189 ! response to X-ray GO:0010165 25 13 1,000 7,825E-04 0,01530642 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,825E-04 0,01518299 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,825E-04 0,01506152 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,825E-04 0,01494199 ! regulation of mRNA stability GO:0043488 31 13 1,000 7,825E-04 0,01482433 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 7,825E-04 0,01470852 ! regulation of bone remodeling GO:0046850 137 57 2,000 8,354E-04 0,01558042 ! regulation of intracellular transport GO:0032386 101 57 2,000 8,354E-04 0,01546057 ! maintenance of location GO:0051235 118 57 2,000 8,354E-04 0,01534255 ! regulation of tissue remodeling GO:0034103 140 58 2,000 8,789E-04 0,01601953 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 9,11E-04 0,01648019 ! tRNA modification GO:0006400 20 14 1,000 9,11E-04 0,0163572 ! negative regulation of caspase activity GO:0043154 22 14 1,000 9,11E-04 0,01623604 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 9,11E-04 0,01611665 ! response to gamma radiation GO:0010332 28 14 1,000 9,11E-04 0,01599901 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 9,11E-04 0,01588308 ! regulation of RNA stability GO:0043487 32 14 1,000 9,11E-04 0,01576881 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 9,702E-04 0,01667305 ! positive regulation of cell size GO:0045793 27 15 1,000 1,049E-03 0,01789909 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,049E-03 0,01777304 ! heterophilic cell adhesion GO:0007157 39 15 1,000 1,049E-03 0,01764875 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,049E-03 0,01752619 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,049E-03 0,01740532 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,067E-03 0,0175878 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,196E-03 0,01958002 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,196E-03 0,01944772 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,196E-03 0,0193172 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,196E-03 0,01918842 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,196E-03 0,01906135 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,196E-03 0,01893594 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,196E-03 0,01881218 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,336E-03 0,02087636 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,336E-03 0,02074167 ! activation of MAPK activity GO:0000187 115 67 2,000 1,336E-03 0,02060871 ! lung development GO:0030324 144 67 2,000 1,336E-03 0,02047745 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,353E-03 0,0206025 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,353E-03 0,02047292 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,353E-03 0,02034496 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,395E-03 0,02084183 ! negative regulation of cell size GO:0045792 134 69 2,000 1,455E-03 0,02160443 ! respiratory tube development GO:0030323 150 70 2,000 1,516E-03 0,02238126 ! memory GO:0007613 31 18 1,000 1,519E-03 0,02228305 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,519E-03 0,022148 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,519E-03 0,02201458 ! B cell activation GO:0042113 160 71 2,000 1,579E-03 0,02275602 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,644E-03 0,02354931 ! respiratory system development GO:0060541 153 72 2,000 1,644E-03 0,02340996 ! skin development GO:0043588 36 19 1,000 1,694E-03 0,02397526 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,694E-03 0,02383506 ! neuromuscular junction development GO:0007528 34 19 1,000 1,694E-03 0,02369648 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,694E-03 0,02355951 ! protein export from nucleus GO:0006611 36 19 1,000 1,694E-03 0,02342411 ! G1 phase GO:0051318 40 19 1,000 1,694E-03 0,02329026 ! lymphocyte differentiation GO:0030098 167 75 2,000 1,849E-03 0,02527415 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,878E-03 0,02553207 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,878E-03 0,02538863 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,878E-03 0,02524679 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 1,878E-03 0,02510653 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,878E-03 0,02496782 ! negative regulation of translation GO:0017148 29 20 1,000 1,878E-03 0,02483064 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,878E-03 0,02469495 ! axis specification GO:0009798 38 21 1,000 2,072E-03 0,02708923 ! positive regulation of locomotion GO:0040017 39 21 1,000 2,072E-03 0,02694281 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 2,072E-03 0,02679795 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,072E-03 0,02665465 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,274E-03 0,0291031 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,274E-03 0,02894912 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,274E-03 0,02879675 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,274E-03 0,02864598 ! activation of JUN kinase activity GO:0007257 42 22 1,000 2,274E-03 0,02849679 ! protein stabilization GO:0050821 39 22 1,000 2,274E-03 0,02834913 ! response to hypoxia GO:0001666 171 81 2,000 2,304E-03 0,0285711 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,386E-03 0,02943565 ! response to oxygen levels GO:0070482 176 83 2,000 2,469E-03 0,03031329 ! leukocyte adhesion GO:0007159 50 23 1,000 2,485E-03 0,03035495 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,485E-03 0,03020164 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 2,485E-03 0,03004987 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,485E-03 0,02989963 ! negative regulation of growth GO:0045926 155 84 2,000 2,555E-03 0,03058302 ! nucleosome assembly GO:0006334 122 85 2,000 2,642E-03 0,03147192 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,706E-03 0,03206849 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,706E-03 0,0319113 ! multicellular organismal response to stress GO:0033555 49 24 1,000 2,706E-03 0,03175563 ! regulation of behavior GO:0050795 43 24 1,000 2,706E-03 0,03160148 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,706E-03 0,03144881 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,706E-03 0,03129762 ! chromatin assembly GO:0031497 124 86 2,000 2,731E-03 0,03144431 ! mitochondrion organization GO:0007005 148 86 2,000 2,731E-03 0,03129457 ! regulation of protein transport GO:0051223 154 87 2,000 2,822E-03 0,03218394 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 2,000 2,915E-03 0,03308591 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,935E-03 0,03315108 ! myelination GO:0042552 45 25 1,000 2,935E-03 0,03299617 ! vasculogenesis GO:0001570 46 25 1,000 2,935E-03 0,0328427 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,935E-03 0,03269065 ! response to starvation GO:0042594 42 25 1,000 2,935E-03 0,03254 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,935E-03 0,03239074 ! negative regulation of cell development GO:0010721 73 25 1,000 2,935E-03 0,03224283 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,935E-03 0,03209627 ! somitogenesis GO:0001756 43 25 1,000 2,935E-03 0,03195104 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,935E-03 0,03180712 ! regulation of cell adhesion GO:0030155 212 89 2,000 3,01E-03 0,03247576 ! regulation of cell cycle process GO:0010564 149 90 2,000 3,107E-03 0,03336824 ! protein-DNA complex assembly GO:0065004 130 90 2,000 3,107E-03 0,03321994 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 3,173E-03 0,03377705 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 3,173E-03 0,03362825 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,173E-03 0,03348076 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,173E-03 0,03333456 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 3,173E-03 0,03318962 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 3,173E-03 0,03304595 ! nucleosome organization GO:0034728 138 92 2,000 3,305E-03 0,03427978 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,419E-03 0,03530929 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,419E-03 0,03515839 ! protein amino acid acylation GO:0043543 55 27 1,000 3,419E-03 0,03500878 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,419E-03 0,03486044 ! base-excision repair GO:0006284 41 27 1,000 3,419E-03 0,03471335 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 3,419E-03 0,0345675 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,419E-03 0,03442286 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,675E-03 0,03683914 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 3,675E-03 0,03668628 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,675E-03 0,03653469 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 3,675E-03 0,03638434 ! leukocyte differentiation GO:0002521 202 96 2,000 3,726E-03 0,03674219 ! regulation of protein localization GO:0032880 176 97 2,000 3,836E-03 0,03767277 ! regulation of pH GO:0006885 43 29 1,000 3,939E-03 0,03852222 ! skeletal muscle tissue development GO:0007519 186 99 2,000 4,062E-03 0,03956883 GO:0060538|skeletal muscle organ development, ! cell junction assembly GO:0034329 78 30 1,000 4,211E-03 0,04085541 ! ensheathment of neurons GO:0007272 57 30 1,000 4,211E-03 0,04069133 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,211E-03 0,04052857 ! regulation of B cell activation GO:0050864 50 30 1,000 4,211E-03 0,0403671 ! response to ionizing radiation GO:0010212 65 32 1,000 4,782E-03 0,04565382 ! peripheral nervous system development GO:0007422 64 32 1,000 4,782E-03 0,04547337 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,782E-03 0,04529434 ! DNA damage checkpoint GO:0000077 71 33 1,000 5,08E-03 0,04792719 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 5,08E-03 0,04773998 ! negative regulation of protein transport GO:0051224 69 33 1,000 5,08E-03 0,04755422 ! positive regulation of endocytosis GO:0045807 50 34 1,000 5,386E-03 0,05022546 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 5,386E-03 0,05003154 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,386E-03 0,04983911 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,7E-03 0,05254725 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,7E-03 0,05234669 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,7E-03 0,05214765 ! cell junction organization GO:0034330 86 36 1,000 6,023E-03 0,05489125 ! maintenance of protein location in cell GO:0032507 86 36 1,000 6,023E-03 0,05468411 ! DNA integrity checkpoint GO:0031570 75 36 1,000 6,023E-03 0,05447853 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 6,023E-03 0,05427449 ! negative regulation of cell activation GO:0050866 65 36 1,000 6,023E-03 0,05407198 ! tissue remodeling GO:0048771 76 37 1,000 6,354E-03 0,05683052 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,354E-03 0,05662004 ! negative regulation of DNA binding GO:0043392 68 37 1,000 6,354E-03 0,05641111 ! regulation of protein stability GO:0031647 73 37 1,000 6,354E-03 0,05620371 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 6,354E-03 0,05599784 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,693E-03 0,05877029 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,693E-03 0,05855658 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,693E-03 0,05834442 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 7,04E-03 0,06114841 ! segmentation GO:0035282 67 39 1,000 7,04E-03 0,06092845 ! regulation of action potential in neuron GO:0019228 73 39 1,000 7,04E-03 0,06071007 ! RNA modification GO:0009451 57 39 1,000 7,04E-03 0,06049325 ! negative regulation of binding GO:0051100 72 40 1,000 7,395E-03 0,06331825 ! maintenance of protein location GO:0045185 91 40 1,000 7,395E-03 0,06309371 ! gliogenesis GO:0042063 88 41 1,000 7,758E-03 0,06595718 ! hormone-mediated signaling GO:0009755 74 41 1,000 7,758E-03 0,06572494 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,758E-03 0,06549433 ! T cell differentiation GO:0030217 81 41 1,000 7,758E-03 0,06526532 ! keratinocyte differentiation GO:0030216 62 41 1,000 7,758E-03 0,06503792 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,758E-03 0,06481209 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 7,758E-03 0,06458783 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 8,129E-03 0,06744257 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 8,129E-03 0,06721081 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 8,508E-03 0,07010168 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 8,508E-03 0,06986242 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 8,508E-03 0,0696248 ! double-strand break repair GO:0006302 81 44 1,000 8,894E-03 0,07254164 ! maintenance of location in cell GO:0051651 97 44 1,000 8,894E-03 0,07229657 ! epidermal cell differentiation GO:0009913 68 46 1,000 9,691E-03 0,0785041 ! response to insulin stimulus GO:0032868 95 46 1,000 9,691E-03 0,07824066 ! positive regulation of protein transport GO:0051222 72 46 1,000 9,691E-03 0,07797899 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01010029 0,08100434 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01010029 0,08073523 ! JNK cascade GO:0007254 91 47 1,000 0,01010029 0,08046789 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01010029 0,08020232 ! protein homooligomerization GO:0051260 76 47 1,000 0,01010029 0,0799385 ! mitochondrial transport GO:0006839 82 48 1,000 0,01051751 0,08296765 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01051751 0,08269651 ! activation of caspase activity GO:0006919 84 48 1,000 0,01051751 0,08242714 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01051751 0,08215952 ! regulation of action potential GO:0001508 95 49 1,000 0,01094226 0,08520091 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,01094226 0,08492607 ! regulation of ossification GO:0030278 117 50 1,000 0,01137449 0,08799686 ! histone modification GO:0016570 91 50 1,000 0,01137449 0,08771482 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01137449 0,08743458 ! positive regulation of binding GO:0051099 78 51 1,000 0,01181415 0,09052496 ! regulation of cell shape GO:0008360 125 51 1,000 0,01181415 0,09023758 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01226118 0,09335569 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01226118 0,09306119 ! synapse organization GO:0050808 85 52 1,000 0,01226118 0,09276855 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01271554 0,09590465 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01317717 0,09907584 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01364602 0,10228142 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01364602 0,10196378 ! heart morphogenesis GO:0003007 97 55 1,000 0,01364602 0,1016481 ! nuclear export GO:0051168 97 55 1,000 0,01364602 0,10133437 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01412205 0,10454665 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01412205 0,10422596 ! muscle fiber development GO:0048747 112 57 1,000 0,01460521 0,10746216 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01460521 0,10713453 ! regulation of endocytosis GO:0030100 91 58 1,000 0,01509543 0,11039395 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01509543 0,11005943 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,01559268 0,11334137 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01600152 0,1159628 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01600152 0,11561457 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01600152 0,11526841 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01600152 0,11492433 ! neuron fate determination GO:0048664 7 5 0,000 0,01600152 0,11458229 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01600152 0,11424229 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01600152 0,11390429 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01600152 0,11356829 ! polyol transport GO:0015791 12 5 0,000 0,01600152 0,11323427 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01600152 0,1129022 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01600152 0,11257208 ! response to superoxide GO:0000303 10 5 0,000 0,01600152 0,11224388 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01600152 0,11191759 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01600152 0,11159319 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01600152 0,11127067 ! female meiosis GO:0007143 7 5 0,000 0,01600152 0,11095 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01600152 0,11063118 ! cobalt ion transport GO:0006824 11 5 0,000 0,01600152 0,11031418 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01600152 0,109999 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01600152 0,10968561 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01600152 0,10937401 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01600152 0,10906417 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01600152 0,10875607 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01600152 0,10844972 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01600152 0,10814509 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01600152 0,10784216 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01600152 0,10754092 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01600152 0,10724137 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01600152 0,10694347 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01600152 0,10664723 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01600152 0,10635263 ! negative chemotaxis GO:0050919 14 5 0,000 0,01600152 0,10605964 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01600152 0,10576827 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01600152 0,10547849 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01600152 0,1051903 ! behavioral response to pain GO:0048266 9 5 0,000 0,01600152 0,10490368 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01600152 0,10461862 ! Notch receptor processing GO:0007220 8 5 0,000 0,01600152 0,1043351 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01600152 0,10405311 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01600152 0,10377264 ! micturition GO:0060073 9 5 0,000 0,01600152 0,10349368 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01600152 0,10321622 ! copulation GO:0007620 9 5 0,000 0,01600152 0,10294024 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01600152 0,10266573 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01600152 0,10239269 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01600152 0,10212109 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01600152 0,10185093 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01600152 0,10158219 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01600152 0,10131487 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01600152 0,10104895 ! grooming behavior GO:0007625 6 5 0,000 0,01600152 0,10078443 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01600152 0,10052128 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01600152 0,10025951 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01600152 0,09999909 ! response to protozoan GO:0001562 10 5 0,000 0,01600152 0,09974003 ! lymph vessel development GO:0001945 10 5 0,000 0,01600152 0,0994823 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01600152 0,0992259 ! endochondral ossification GO:0001958 16 5 0,000 0,01600152 0,09897082 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01600152 0,09871705 ! parathyroid gland development GO:0060017 13 5 0,000 0,01600152 0,09846458 ! anagen GO:0042640 6 5 0,000 0,01600152 0,09821339 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01600152 0,09796349 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01600152 0,09771485 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01600152 0,09746747 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01600152 0,09722134 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01600152 0,09697645 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01600152 0,09673279 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01600152 0,09649035 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01600152 0,09624913 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01600152 0,0960091 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01600152 0,09577027 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01600152 0,09553263 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01600152 0,09529616 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01600152 0,09506087 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01600152 0,09482673 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01600152 0,09459374 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01600152 0,09436189 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01600152 0,09413117 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01600152 0,09390159 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01600152 0,09367312 ! histidine catabolic process GO:0006548 6 5 0,000 0,01600152 0,09344575 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01600152 0,09321949 ! microvillus organization GO:0032528 7 5 0,000 0,01600152 0,09299432 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01600152 0,09277024 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01600152 0,09254724 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01600152 0,0923253 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01600152 0,09210443 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01600152 0,09188461 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01600152 0,09166583 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01600152 0,0914481 ! polyol catabolic process GO:0046174 7 5 0,000 0,01600152 0,0912314 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01600152 0,09101572 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01600152 0,09080106 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01600152 0,09058741 ! muscle cell migration GO:0014812 8 5 0,000 0,01600152 0,09037477 ! mitochondrial fission GO:0000266 8 5 0,000 0,01600152 0,09016312 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01600152 0,08995245 ! mRNA transcription GO:0009299 9 5 0,000 0,01600152 0,08974278 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01600152 0,08953407 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01600152 0,08932634 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01600152 0,08911956 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01600152 0,08891374 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01600152 0,08870887 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01600152 0,08850494 ! response to food GO:0032094 6 5 0,000 0,01600152 0,08830195 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01600152 0,08809989 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01600152 0,08789875 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01600152 0,08769852 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01600152 0,08749921 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01600152 0,08730079 ! forebrain neuron development GO:0021884 13 5 0,000 0,01600152 0,08710328 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01600152 0,08690666 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01600152 0,08671092 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01600152 0,08651607 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01600152 0,08632209 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01600152 0,08612897 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01600152 0,08593672 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01600152 0,08574532 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01600152 0,08555478 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01600152 0,08536508 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01600152 0,08517622 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01600152 0,08498819 ! basic amino acid transport GO:0015802 11 5 0,000 0,01600152 0,08480099 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01600152 0,08461462 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01600152 0,08442906 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01600152 0,08424431 ! depyrimidination GO:0045008 10 5 0,000 0,01600152 0,08406037 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01600152 0,08387723 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01600152 0,08369489 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01600152 0,08351334 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01600152 0,08333258 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01600152 0,08315259 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01600152 0,08297338 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01600152 0,08279495 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01600152 0,08261728 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01600152 0,08244037 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01600152 0,08226421 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01600152 0,08208881 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01600152 0,08191415 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01600152 0,08174023 ! response to arsenic GO:0046685 10 5 0,000 0,01600152 0,08156706 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01600152 0,08139461 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01600152 0,08122289 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01600152 0,0810519 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01600152 0,08088162 ! response to cadmium ion GO:0046686 7 5 0,000 0,01600152 0,08071206 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01600152 0,0805432 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01600152 0,08037505 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01600152 0,08020761 ! decidualization GO:0046697 11 5 0,000 0,01600152 0,08004085 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01600152 0,07987479 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01600152 0,07970942 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01600152 0,07954473 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01600152 0,07938072 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01600152 0,07921739 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01600152 0,07905472 ! neural tube patterning GO:0021532 7 5 0,000 0,01600152 0,07889273 ! embryonic cleavage GO:0040016 6 5 0,000 0,01600152 0,07873139 ! peroxisome fission GO:0016559 5 5 0,000 0,01600152 0,07857072 ! histone demethylation GO:0016577 10 5 0,000 0,01600152 0,07841069 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01600152 0,07825132 ! mitotic recombination GO:0006312 9 5 0,000 0,01600152 0,0780926 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01600152 0,07793452 ! metaphase plate congression GO:0051310 7 5 0,000 0,01600152 0,07777707 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01600152 0,07762026 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01600152 0,07746409 ! enteric nervous system development GO:0048484 8 5 0,000 0,01600152 0,07730854 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01600152 0,07715361 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01600152 0,0769993 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01600152 0,07684561 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01600152 0,07669253 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01600152 0,07654006 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01600152 0,0763882 ! plasminogen activation GO:0031639 5 5 0,000 0,01600152 0,07623693 ! B cell homeostasis GO:0001782 13 5 0,000 0,01600152 0,07608627 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01600152 0,07593619 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01600152 0,07578671 ! metaphase GO:0051323 8 5 0,000 0,01600152 0,07563782 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01600152 0,07548951 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01600152 0,07534178 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01600152 0,07519463 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01600152 0,07504805 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01600152 0,07490204 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01600152 0,0747566 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01600152 0,07461173 ! response to redox state GO:0051775 5 5 0,000 0,01600152 0,07446741 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01600152 0,07432365 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01600152 0,07418044 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01600152 0,07403779 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01600152 0,07389568 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01600152 0,07375412 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01600152 0,0736131 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01600152 0,07347262 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01600152 0,07333267 ! striatum development GO:0021756 9 5 0,000 0,01600152 0,07319325 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01600152 0,07305437 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01600152 0,072916 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01600152 0,07277817 ! glial cell migration GO:0008347 11 5 0,000 0,01600152 0,07264085 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01600152 0,07250405 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01600152 0,07236776 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01600152 0,07223199 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01600152 0,07209672 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01600152 0,07196196 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01600152 0,07182771 ! neuroprotection GO:0043526 6 5 0,000 0,01600152 0,07169395 ! neural plate development GO:0001840 8 5 0,000 0,01600152 0,07156069 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01600152 0,07142792 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01600152 0,07129565 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01600152 0,07116386 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01600152 0,07103257 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01600152 0,07090175 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01600152 0,07077142 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01600152 0,07064156 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01600152 0,07051218 ! spindle assembly GO:0051225 6 5 0,000 0,01600152 0,07038327 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01600152 0,07025484 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01600152 0,07012687 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01600152 0,06999936 ! drug metabolic process GO:0017144 6 5 0,000 0,01600152 0,06987232 ! stem cell division GO:0017145 11 5 0,000 0,01600152 0,06974574 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01600152 0,06961962 ! organ regeneration GO:0031100 7 5 0,000 0,01600152 0,06949395 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01600152 0,06936874 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01600152 0,06924398 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01600152 0,06911966 ! tRNA processing GO:0008033 89 61 1,000 0,01660806 0,07161109 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01660806 0,07148298 ! viral reproductive process GO:0022415 126 62 1,000 0,01712608 0,073581 ! regulation of mitosis GO:0007088 105 63 1,000 0,01765094 0,07570082 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01765094 0,07556612 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01917128 0,08192912 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01917128 0,08178386 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01917128 0,08163911 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01917128 0,08149487 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01917128 0,08135114 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01917128 0,08120792 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01917128 0,0810652 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01917128 0,08092298 ! sleep GO:0030431 13 6 0,000 0,01917128 0,08078125 ! response to oxygen radical GO:0000305 11 6 0,000 0,01917128 0,08064003 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01917128 0,0804993 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01917128 0,08035905 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01917128 0,0802193 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01917128 0,08008003 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01917128 0,07994124 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01917128 0,07980293 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01917128 0,07966511 ! forebrain regionalization GO:0021871 8 6 0,000 0,01917128 0,07952775 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01917128 0,07939087 ! male meiosis GO:0007140 7 6 0,000 0,01917128 0,07925446 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01917128 0,07911852 ! response to zinc ion GO:0010043 9 6 0,000 0,01917128 0,07898304 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01917128 0,07884803 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01917128 0,07871347 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01917128 0,07857938 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01917128 0,07844574 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01917128 0,07831256 ! malate metabolic process GO:0006108 11 6 0,000 0,01917128 0,07817982 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01917128 0,07804754 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01917128 0,0779157 ! protein refolding GO:0042026 15 6 0,000 0,01917128 0,07778431 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01917128 0,07765336 ! opsonization GO:0008228 8 6 0,000 0,01917128 0,07752285 ! mating behavior GO:0007617 7 6 0,000 0,01917128 0,07739278 ! neuron remodeling GO:0016322 15 6 0,000 0,01917128 0,07726314 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01917128 0,07713394 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01917128 0,07700517 ! equilibrioception GO:0050957 14 6 0,000 0,01917128 0,07687683 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01917128 0,07674891 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01917128 0,07662142 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01917128 0,07649436 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01917128 0,07636771 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01917128 0,07624148 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01917128 0,07611567 ! toxin metabolic process GO:0009404 11 6 0,000 0,01917128 0,07599027 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01917128 0,07586529 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01917128 0,07574072 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01917128 0,07561655 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01917128 0,07549279 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01917128 0,07536944 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01917128 0,07524649 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01917128 0,07512394 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01917128 0,07500178 ! thymic T cell selection GO:0045061 12 6 0,000 0,01917128 0,07488003 ! protein lipoylation GO:0009249 10 6 0,000 0,01917128 0,07475866 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01917128 0,0746377 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01917128 0,07451712 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01917128 0,07439693 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01917128 0,07427713 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01917128 0,07415771 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01917128 0,07403868 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01917128 0,07392003 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01917128 0,07380175 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01917128 0,07368386 ! hyperosmotic response GO:0006972 9 6 0,000 0,01917128 0,07356634 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01917128 0,0734492 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01917128 0,07333243 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01917128 0,07321603 ! urea metabolic process GO:0019627 7 6 0,000 0,01917128 0,07309999 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01917128 0,07298433 ! neutrophil activation GO:0042119 8 6 0,000 0,01917128 0,07286903 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01917128 0,07275409 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01917128 0,07263952 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01917128 0,07252531 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01917128 0,07241145 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01917128 0,07229796 ! neuron apoptosis GO:0051402 9 6 0,000 0,01917128 0,07218481 ! nucleoside salvage GO:0043174 9 6 0,000 0,01917128 0,07207203 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01917128 0,07195959 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01917128 0,0718475 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01917128 0,07173576 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01917128 0,07162437 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01917128 0,07151333 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01917128 0,07140263 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01917128 0,07129227 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01917128 0,07118225 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01917128 0,07107257 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01917128 0,07096322 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01917128 0,07085422 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01917128 0,07074555 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01917128 0,07063721 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01917128 0,0705292 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01917128 0,07042152 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01917128 0,07031417 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01917128 0,07020715 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01917128 0,07010045 ! neural nucleus development GO:0048857 14 6 0,000 0,01917128 0,06999408 ! response to UV-C GO:0010225 11 6 0,000 0,01917128 0,06988802 ! astrocyte development GO:0014002 15 6 0,000 0,01917128 0,06978229 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01917128 0,06967688 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01917128 0,06957179 ! interaction with symbiont GO:0051702 13 6 0,000 0,01917128 0,06946701 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01917128 0,06936255 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01917128 0,0692584 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01917128 0,06915457 ! response to copper ion GO:0046688 10 6 0,000 0,01917128 0,06905104 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01917128 0,06894783 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01917128 0,06884492 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01917128 0,06874232 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01917128 0,06864002 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01917128 0,06853803 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01917128 0,06843634 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01917128 0,06833496 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01917128 0,06823387 ! hair follicle maturation GO:0048820 7 6 0,000 0,01917128 0,06813308 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01917128 0,06803259 ! Schwann cell development GO:0014044 15 6 0,000 0,01917128 0,0679324 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01917128 0,06783249 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01917128 0,06773289 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01917128 0,06763357 ! subpallium development GO:0021544 10 6 0,000 0,01917128 0,06753455 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01917128 0,06743581 ! histone ubiquitination GO:0016574 8 6 0,000 0,01917128 0,06733737 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01917128 0,06723921 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01917128 0,06714133 ! G2 phase GO:0051319 16 6 0,000 0,01917128 0,06704374 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01917128 0,06694644 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01917128 0,06684941 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01917128 0,06675267 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01917128 0,06665621 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01917128 0,06656002 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01917128 0,06646412 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01917128 0,06636848 ! receptor internalization GO:0031623 10 6 0,000 0,01917128 0,06627313 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01917128 0,06617804 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01917128 0,06608323 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01917128 0,06598869 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01917128 0,06589442 ! protein deubiquitination GO:0016579 14 6 0,000 0,01917128 0,06580042 ! protein destabilization GO:0031648 9 6 0,000 0,01917128 0,06570669 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01917128 0,06561322 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01917128 0,06552002 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01917128 0,06542709 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01917128 0,06533441 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01917128 0,065242 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01917128 0,06514985 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01917128 0,06505796 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01917128 0,06496633 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01917128 0,06487496 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01917128 0,06478384 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01917128 0,06469298 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01917128 0,06460238 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01917128 0,06451202 ! catecholamine transport GO:0051937 9 6 0,000 0,01917128 0,06442192 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01917128 0,06433207 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01917128 0,06424247 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01917128 0,06415312 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01917128 0,06406402 ! maternal placenta development GO:0001893 12 6 0,000 0,01917128 0,06397517 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01917128 0,06388656 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01917128 0,0637982 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01917128 0,06371008 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01917128 0,0636222 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01917128 0,06353457 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01917128 0,06344717 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01917128 0,06336002 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,01981767 0,06540648 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01981767 0,06531688 ! adaptive immune response GO:0002250 119 67 1,000 0,01981767 0,06522753 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02037595 0,0669734 ! viral reproduction GO:0016032 134 68 1,000 0,02037595 0,06688203 ! regulation of lipase activity GO:0060191 130 68 1,000 0,02037595 0,06679091 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02094076 0,06854894 ! antigen processing and presentation GO:0019882 104 69 1,000 0,02094076 0,0684558 ! humoral immune response GO:0006959 109 71 1,000 0,02208983 0,07211414 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,02208983 0,07201642 ! tRNA transcription GO:0009304 14 7 0,000 0,02233093 0,07270396 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02233093 0,07260571 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02233093 0,07250773 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02233093 0,07241001 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02233093 0,07231255 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02233093 0,07221536 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02233093 0,07211843 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02233093 0,07202175 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02233093 0,07192534 ! prostate gland development GO:0030850 13 7 0,000 0,02233093 0,07182918 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02233093 0,07173328 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02233093 0,07163764 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02233093 0,07154225 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02233093 0,07144711 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02233093 0,07135223 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02233093 0,0712576 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02233093 0,07116321 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02233093 0,07106908 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02233093 0,0709752 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02233093 0,07088157 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02233093 0,07078818 ! glycolipid transport GO:0046836 10 7 0,000 0,02233093 0,07069504 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02233093 0,07060214 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02233093 0,07050948 ! neuron adhesion GO:0007158 12 7 0,000 0,02233093 0,07041707 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02233093 0,0703249 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02233093 0,07023298 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02233093 0,07014129 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02233093 0,07004984 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02233093 0,06995863 ! pericardium development GO:0060039 14 7 0,000 0,02233093 0,06986766 ! fibril organization GO:0043206 16 7 0,000 0,02233093 0,06977692 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02233093 0,06968642 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02233093 0,06959615 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02233093 0,06950612 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02233093 0,06941631 ! lipoprotein transport GO:0042953 14 7 0,000 0,02233093 0,06932674 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02233093 0,06923741 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02233093 0,0691483 ! rhythmic behavior GO:0007622 15 7 0,000 0,02233093 0,06905942 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02233093 0,06897077 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02233093 0,06888234 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02233093 0,06879415 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02233093 0,06870617 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02233093 0,06861843 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02233093 0,0685309 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02233093 0,0684436 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02233093 0,06835652 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02233093 0,06826967 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02233093 0,06818303 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02233093 0,06809661 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02233093 0,06801041 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02233093 0,06792443 ! spinal cord patterning GO:0021511 13 7 0,000 0,02233093 0,06783867 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02233093 0,06775312 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02233093 0,06766779 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02233093 0,06758268 ! adrenal gland development GO:0030325 17 7 0,000 0,02233093 0,06749777 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02233093 0,06741308 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02233093 0,06732861 ! ovulation GO:0030728 9 7 0,000 0,02233093 0,06724434 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02233093 0,06716028 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02233093 0,06707644 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02233093 0,0669928 ! microtubule nucleation GO:0007020 20 7 0,000 0,02233093 0,06690937 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02233093 0,06682615 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02233093 0,06674314 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02233093 0,06666033 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02233093 0,06657773 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02233093 0,06649533 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02233093 0,06641314 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02233093 0,06633114 ! galactose metabolic process GO:0006012 13 7 0,000 0,02233093 0,06624936 ! vesicle fusion GO:0006906 17 7 0,000 0,02233093 0,06616777 ! response to dietary excess GO:0002021 8 7 0,000 0,02233093 0,06608638 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02233093 0,06600519 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02233093 0,06592421 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02233093 0,06584342 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02233093 0,06576282 ! organ growth GO:0035265 15 7 0,000 0,02233093 0,06568243 ! purine salvage GO:0043101 10 7 0,000 0,02233093 0,06560223 ! nucleoside transport GO:0015858 8 7 0,000 0,02233093 0,06552223 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02233093 0,06544242 ! parturition GO:0007567 14 7 0,000 0,02233093 0,06536281 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02233093 0,06528339 ! rRNA modification GO:0000154 14 7 0,000 0,02233093 0,06520416 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02233093 0,06512512 ! spindle checkpoint GO:0031577 15 7 0,000 0,02233093 0,06504628 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02233093 0,06496763 ! macrophage differentiation GO:0030225 11 7 0,000 0,02233093 0,06488916 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02233093 0,06481089 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02233093 0,0647328 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02233093 0,06465491 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02233093 0,0645772 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02233093 0,06449967 ! fibrinolysis GO:0042730 10 7 0,000 0,02233093 0,06442233 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02233093 0,06434518 ! eating behavior GO:0042755 7 7 0,000 0,02233093 0,06426821 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02233093 0,06419143 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02233093 0,06411483 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02233093 0,06403841 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02233093 0,06396218 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02233093 0,06388612 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02233093 0,06381025 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02233093 0,06373455 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02233093 0,06365904 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02233093 0,0635837 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02233093 0,06350854 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02233093 0,06343356 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02233093 0,06335876 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02233093 0,06328413 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02233093 0,06320968 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02233093 0,0631354 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02233093 0,0630613 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02233093 0,06298737 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02233093 0,06291362 ! transcription termination GO:0006353 13 7 0,000 0,02233093 0,06284003 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02233093 0,06276662 ! anaphase GO:0051322 17 7 0,000 0,02233093 0,06269338 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02233093 0,06262031 ! axonal fasciculation GO:0007413 18 7 0,000 0,02233093 0,06254741 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02233093 0,06247468 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02233093 0,06240212 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02233093 0,06232973 ! diuresis GO:0030146 12 7 0,000 0,02233093 0,06225751 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02233093 0,06218545 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02233093 0,06211356 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02233093 0,06204183 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02233093 0,06197027 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02233093 0,06189888 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02233093 0,06182765 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02233093 0,06175658 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02233093 0,06168568 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02233093 0,06161494 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02233093 0,06154436 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02233093 0,06147394 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02233093 0,06140369 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02233093 0,06133359 ! lymph node development GO:0048535 10 7 0,000 0,02233093 0,06126366 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02233093 0,06119388 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02233093 0,06112426 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02233093 0,0610548 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02233093 0,0609855 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02233093 0,06091636 ! adult feeding behavior GO:0008343 9 7 0,000 0,02233093 0,06084737 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02233093 0,06077854 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02233093 0,06070986 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02233093 0,06064134 ! muscle adaptation GO:0043500 14 7 0,000 0,02233093 0,06057297 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02233093 0,06050476 ! retina homeostasis GO:0001895 12 7 0,000 0,02233093 0,0604367 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02233093 0,06036879 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02233093 0,06030104 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02233093 0,06023344 ! protein prenylation GO:0018342 18 7 0,000 0,02233093 0,06016599 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02233093 0,06009869 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02233093 0,06003154 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02233093 0,05996454 ! learning or memory GO:0007611 147 73 1,000 0,02326449 0,06240175 ! axon guidance GO:0007411 139 73 1,000 0,02326449 0,06233226 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02386131 0,0638602 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02446439 0,06540148 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,02446439 0,06532889 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02507369 0,06688172 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02548052 0,06789161 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02548052 0,0678165 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02548052 0,06774157 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02548052 0,0676668 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02548052 0,06759219 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02548052 0,06751775 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02548052 0,06744348 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02548052 0,06736936 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02548052 0,06729541 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02548052 0,06722162 ! meiotic prophase I GO:0007128 13 8 0,000 0,02548052 0,067148 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02548052 0,06707453 ! oligopeptide transport GO:0006857 15 8 0,000 0,02548052 0,06700122 ! UTP metabolic process GO:0046051 8 8 0,000 0,02548052 0,06692808 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02548052 0,06685509 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02548052 0,06678227 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02548052 0,0667096 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02548052 0,06663709 ! succinate metabolic process GO:0006105 14 8 0,000 0,02548052 0,06656473 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02548052 0,06649254 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02548052 0,0664205 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02548052 0,06634862 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02548052 0,06627689 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02548052 0,06620531 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02548052 0,06613389 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02548052 0,06606263 ! reflex GO:0060004 16 8 0,000 0,02548052 0,06599152 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02548052 0,06592056 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02548052 0,06584975 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02548052 0,0657791 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02548052 0,0657086 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02548052 0,06563824 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02548052 0,06556804 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02548052 0,06549799 ! pigment granule organization GO:0048753 16 8 0,000 0,02548052 0,06542809 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02548052 0,06535834 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02548052 0,06528873 ! histidine metabolic process GO:0006547 16 8 0,000 0,02548052 0,06521928 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02548052 0,06514997 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02548052 0,06508081 ! glycine catabolic process GO:0006546 13 8 0,000 0,02548052 0,06501179 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02548052 0,06494292 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02548052 0,0648742 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02548052 0,06480562 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02548052 0,06473719 ! melanin metabolic process GO:0006582 15 8 0,000 0,02548052 0,0646689 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02548052 0,06460076 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02548052 0,06453276 ! macrophage activation GO:0042116 12 8 0,000 0,02548052 0,0644649 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02548052 0,06439719 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02548052 0,06432961 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02548052 0,06426218 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02548052 0,06419489 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02548052 0,06412774 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02548052 0,06406073 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02548052 0,06399386 ! osteoblast development GO:0002076 16 8 0,000 0,02548052 0,06392713 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02548052 0,06386054 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02548052 0,06379409 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02548052 0,06372778 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02548052 0,0636616 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02548052 0,06359556 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02548052 0,06352966 ! response to UV-B GO:0010224 16 8 0,000 0,02548052 0,06346389 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02548052 0,06339826 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02548052 0,06333277 ! intermediate filament organization GO:0045109 12 8 0,000 0,02548052 0,06326741 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02548052 0,06320219 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02548052 0,0631371 ! cellular extravasation GO:0045123 12 8 0,000 0,02548052 0,06307214 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02548052 0,06300732 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02548052 0,06294263 ! response to antibiotic GO:0046677 11 8 0,000 0,02548052 0,06287807 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02548052 0,06281365 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02548052 0,06274936 ! DNA topological change GO:0006265 12 8 0,000 0,02548052 0,06268519 ! response to tropane GO:0014073 15 8 0,000 0,02548052 0,06262116 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02548052 0,06255727 ! melanosome transport GO:0032402 13 8 0,000 0,02548052 0,0624935 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02548052 0,06242986 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02548052 0,06236635 ! mast cell activation GO:0045576 14 8 0,000 0,02548052 0,06230297 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02548052 0,06223972 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02548052 0,06217659 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02548052 0,0621136 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02548052 0,06205073 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02548052 0,06198799 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02548052 0,06192537 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02548052 0,06186289 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02548052 0,06180052 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02548052 0,06173829 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02548052 0,06167618 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02548052 0,06161419 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02548052 0,06155233 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02548052 0,06149059 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02548052 0,06142898 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02548052 0,06136749 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02548052 0,06130612 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02548052 0,06124488 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02548052 0,06118375 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02548052 0,06112275 ! hormone catabolic process GO:0042447 17 8 0,000 0,02548052 0,06106187 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02548052 0,06100111 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02548052 0,06094048 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02548052 0,06087996 ! ATP catabolic process GO:0006200 11 8 0,000 0,02548052 0,06081956 ! blastocyst growth GO:0001832 19 8 0,000 0,02548052 0,06075929 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02548052 0,06069913 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02548052 0,06063909 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02548052 0,06057917 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02548052 0,06051937 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02548052 0,06045968 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02548052 0,06040012 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02548052 0,06034067 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02548052 0,06028134 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02548052 0,06022212 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02548052 0,06016302 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02548052 0,06010404 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02548052 0,06004517 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02548052 0,05998642 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02548052 0,05992778 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02548052 0,05986926 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02548052 0,05981085 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02568916 0,06024184 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02693844 0,06310992 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02693844 0,06304853 ! protein import into nucleus GO:0006606 158 80 1,000 0,02757215 0,064469 ! T cell activation GO:0042110 168 81 1,000 0,02821186 0,06590072 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02821186 0,0658368 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,02821186 0,065773 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,02821186 0,06570933 ! axon extension GO:0048675 15 9 0,000 0,02862005 0,0665956 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02862005 0,06653126 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02862005 0,06646704 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02862005 0,06640294 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02862005 0,06633897 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02862005 0,06627512 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02862005 0,0662114 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02862005 0,06614779 ! phosphate transport GO:0006817 19 9 0,000 0,02862005 0,06608431 ! reproductive behavior GO:0019098 19 9 0,000 0,02862005 0,06602095 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02862005 0,06595771 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02862005 0,0658946 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02862005 0,0658316 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02862005 0,06576872 ! GTP metabolic process GO:0046039 9 9 0,000 0,02862005 0,06570597 ! RNA methylation GO:0001510 15 9 0,000 0,02862005 0,06564333 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02862005 0,06558081 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02862005 0,06551841 ! artery development GO:0060840 24 9 0,000 0,02862005 0,06545613 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02862005 0,06539397 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02862005 0,06533193 ! chemosensory behavior GO:0007635 20 9 0,000 0,02862005 0,06527 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02862005 0,06520819 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02862005 0,0651465 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02862005 0,06508493 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02862005 0,06502347 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02862005 0,06496212 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02862005 0,0649009 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02862005 0,06483979 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02862005 0,06477879 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02862005 0,06471791 ! protein targeting to ER GO:0045047 22 9 0,000 0,02862005 0,06465714 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02862005 0,06459648 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02862005 0,06453594 ! T cell selection GO:0045058 23 9 0,000 0,02862005 0,06447552 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02862005 0,0644152 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02862005 0,064355 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02862005 0,06429491 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02862005 0,06423494 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02862005 0,06417507 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02862005 0,06411532 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02862005 0,06405568 ! mannose metabolic process GO:0006013 13 9 0,000 0,02862005 0,06399615 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02862005 0,06393672 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02862005 0,06387741 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02862005 0,06381821 ! receptor clustering GO:0043113 18 9 0,000 0,02862005 0,06375912 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02862005 0,06370014 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02862005 0,06364127 ! ruffle organization GO:0031529 15 9 0,000 0,02862005 0,0635825 ! retinol metabolic process GO:0042572 18 9 0,000 0,02862005 0,06352385 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02862005 0,0634653 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02862005 0,06340686 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02862005 0,06334853 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02862005 0,06329031 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02862005 0,06323219 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02862005 0,06317418 ! segment specification GO:0007379 13 9 0,000 0,02862005 0,06311627 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02862005 0,06305847 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02862005 0,06300078 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02862005 0,06294319 ! response to amine stimulus GO:0014075 13 9 0,000 0,02862005 0,06288571 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02862005 0,06282833 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02862005 0,06277106 ! erythrocyte development GO:0048821 15 9 0,000 0,02862005 0,06271389 ! gas homeostasis GO:0033483 16 9 0,000 0,02862005 0,06265683 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02862005 0,06259987 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02862005 0,06254301 ! renal water homeostasis GO:0003091 14 9 0,000 0,02862005 0,06248625 ! postreplication repair GO:0006301 22 9 0,000 0,02862005 0,0624296 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02862005 0,06237305 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02862005 0,06231661 ! icosanoid secretion GO:0032309 15 9 0,000 0,02862005 0,06226026 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02862005 0,06220402 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02862005 0,06214788 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02862005 0,06209184 ! regulation of cell division GO:0051302 15 9 0,000 0,02862005 0,0620359 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02862005 0,06198006 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02862005 0,06192433 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02862005 0,06186869 ! sterol catabolic process GO:0016127 11 9 0,000 0,02862005 0,06181315 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02862005 0,06175771 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02862005 0,06170238 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02862005 0,06164714 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02862005 0,061592 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02862005 0,06153695 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02862005 0,06148201 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02862005 0,06142717 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02862005 0,06137242 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02862005 0,06131777 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02862005 0,06126321 ! purine base metabolic process GO:0006144 21 9 0,000 0,02862005 0,06120876 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02862005 0,0611544 ! pigment granule transport GO:0051904 17 9 0,000 0,02862005 0,06110013 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02862005 0,06104597 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02862005 0,0609919 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02862005 0,06093792 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02862005 0,06088404 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02862005 0,06083026 ! mitochondrion localization GO:0051646 15 9 0,000 0,02862005 0,06077657 ! response to drug GO:0042493 143 82 1,000 0,02885752 0,06122679 ! negative regulation of transport GO:0051051 153 84 1,000 0,03016649 0,06394765 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03082973 0,06529605 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03174958 0,06718513 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03174958 0,0671261 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03174958 0,06706716 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03174958 0,06700833 ! synapsis GO:0007129 13 10 0,000 0,03174958 0,0669496 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03174958 0,06689098 ! N-glycan processing GO:0006491 20 10 0,000 0,03174958 0,06683246 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03174958 0,06677404 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03174958 0,06671572 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03174958 0,0666575 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03174958 0,06659939 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03174958 0,06654137 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03174958 0,06648346 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03174958 0,06642565 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03174958 0,06636794 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03174958 0,06631033 ! androgen metabolic process GO:0008209 17 10 0,000 0,03174958 0,06625282 ! phospholipid efflux GO:0033700 16 10 0,000 0,03174958 0,06619541 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03174958 0,06613809 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03174958 0,06608088 ! pathogenesis GO:0009405 13 10 0,000 0,03174958 0,06602377 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03174958 0,06596675 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03174958 0,06590983 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03174958 0,06585302 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03174958 0,06579629 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03174958 0,06573967 ! endoderm development GO:0007492 16 10 0,000 0,03174958 0,06568315 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03174958 0,06562672 ! arginine catabolic process GO:0006527 13 10 0,000 0,03174958 0,06557038 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03174958 0,06551415 ! proline metabolic process GO:0006560 13 10 0,000 0,03174958 0,06545801 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03174958 0,06540197 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03174958 0,06534602 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03174958 0,06529017 ! V(D)J recombination GO:0033151 28 10 0,000 0,03174958 0,06523441 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03174958 0,06517875 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03174958 0,06512319 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03174958 0,06506772 ! B cell proliferation GO:0042100 18 10 0,000 0,03174958 0,06501234 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03174958 0,06495706 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03174958 0,06490187 ! multicellular organism growth GO:0035264 18 10 0,000 0,03174958 0,06484677 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03174958 0,06479177 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03174958 0,06473686 ! epithelial cell development GO:0002064 20 10 0,000 0,03174958 0,06468205 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03174958 0,06462733 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03174958 0,0645727 ! macroautophagy GO:0016236 17 10 0,000 0,03174958 0,06451816 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03174958 0,06446371 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03174958 0,06440936 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03174958 0,0643551 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03174958 0,06430092 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03174958 0,06424684 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03174958 0,06419286 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03174958 0,06413896 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03174958 0,06408515 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03174958 0,06403143 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03174958 0,0639778 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03174958 0,06392427 ! response to dsRNA GO:0043331 20 10 0,000 0,03174958 0,06387082 ! DNA ligation GO:0006266 19 10 0,000 0,03174958 0,06381746 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03174958 0,06376419 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03174958 0,06371101 ! melanosome localization GO:0032400 16 10 0,000 0,03174958 0,06365792 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03174958 0,06360491 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03174958 0,063552 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03174958 0,06349917 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03174958 0,06344643 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03174958 0,06339377 ! mRNA cleavage GO:0006379 17 10 0,000 0,03174958 0,06334121 ! protein sumoylation GO:0016925 15 10 0,000 0,03174958 0,06328873 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03174958 0,06323634 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03174958 0,06318404 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03174958 0,06313182 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03174958 0,06307968 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03174958 0,06302764 ! salivary gland development GO:0007431 27 10 0,000 0,03174958 0,06297568 ! prophase GO:0051324 15 10 0,000 0,03174958 0,0629238 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03174958 0,06287202 ! apical protein localization GO:0045176 15 10 0,000 0,03174958 0,06282031 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03174958 0,06276869 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03174958 0,06271716 ! midbrain development GO:0030901 13 10 0,000 0,03174958 0,06266571 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03174958 0,06261434 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03174958 0,06256306 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03174958 0,06251186 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03174958 0,06246075 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03174958 0,06240972 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03174958 0,06235877 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03174958 0,06230791 ! detection of calcium ion GO:0005513 23 10 0,000 0,03174958 0,06225713 ! oocyte development GO:0048599 17 10 0,000 0,03174958 0,06220643 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03174958 0,06215582 ! blastocyst formation GO:0001825 17 10 0,000 0,03174958 0,06210528 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03174958 0,06205483 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03174958 0,06200446 ! activation of innate immune response GO:0002218 12 10 0,000 0,03174958 0,06195418 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03174958 0,06190397 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03174958 0,06185384 ! response to nicotine GO:0035094 20 10 0,000 0,03174958 0,0618038 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03174958 0,06175384 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03174958 0,06170396 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03217347 0,06247729 ! gland development GO:0048732 206 88 1,000 0,03285389 0,06374715 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03353996 0,06502589 ! ossification GO:0001503 188 90 1,000 0,03423162 0,06631343 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03486913 0,06749408 ! respiratory burst GO:0045730 17 11 0,000 0,03486913 0,06743982 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03486913 0,06738565 ! neuron fate specification GO:0048665 17 11 0,000 0,03486913 0,06733157 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03486913 0,06727757 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03486913 0,06722367 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,03486913 0,06716984 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03486913 0,06711611 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03486913 0,06706246 ! response to pain GO:0048265 24 11 0,000 0,03486913 0,06700889 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03486913 0,06695542 ! T cell proliferation GO:0042098 26 11 0,000 0,03486913 0,06690202 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03486913 0,06684871 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03486913 0,06679549 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03486913 0,06674235 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03486913 0,0666893 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03486913 0,06663633 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03486913 0,06658344 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03486913 0,06653064 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03486913 0,06647792 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03486913 0,06642529 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03486913 0,06637273 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03486913 0,06632027 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03486913 0,06626788 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03486913 0,06621558 ! UV protection GO:0009650 19 11 0,000 0,03486913 0,06616336 ! adult heart development GO:0007512 14 11 0,000 0,03486913 0,06611122 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03486913 0,06605916 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03486913 0,06600719 ! temperature homeostasis GO:0001659 17 11 0,000 0,03486913 0,0659553 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03486913 0,06590348 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03486913 0,06585175 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03486913 0,06580011 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03486913 0,06574854 ! regulation of organ growth GO:0046620 13 11 0,000 0,03486913 0,06569705 ! pigment granule localization GO:0051875 20 11 0,000 0,03486913 0,06564565 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03486913 0,06559432 ! vasoconstriction GO:0042310 18 11 0,000 0,03486913 0,06554307 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03486913 0,06549191 ! embryonic axis specification GO:0000578 18 11 0,000 0,03486913 0,06544082 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03486913 0,06538982 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03486913 0,06533889 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03486913 0,06528804 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03486913 0,06523728 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03486913 0,06518659 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03486913 0,06513597 ! zymogen activation GO:0031638 15 11 0,000 0,03486913 0,06508544 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03486913 0,06503499 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03486913 0,06498461 ! nucleosome positioning GO:0016584 15 11 0,000 0,03486913 0,06493432 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03486913 0,0648841 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03486913 0,06483395 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03486913 0,06478389 ! acid secretion GO:0046717 18 11 0,000 0,03486913 0,0647339 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03486913 0,06468399 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03486913 0,06463416 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03486913 0,0645844 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03486913 0,06453472 ! oocyte differentiation GO:0009994 18 11 0,000 0,03486913 0,06448512 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03486913 0,06443559 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03486913 0,06438614 ! cholesterol efflux GO:0033344 19 11 0,000 0,03486913 0,06433676 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03486913 0,06428746 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03486913 0,06423824 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03486913 0,06418909 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03486913 0,06414001 ! embryonic gut development GO:0048566 15 11 0,000 0,03486913 0,06409101 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03486913 0,06404209 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03486913 0,06399324 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03486913 0,06394446 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03486913 0,06389576 ! defense response to fungus GO:0050832 13 11 0,000 0,03486913 0,06384714 ! developmental induction GO:0031128 19 11 0,000 0,03486913 0,06379858 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03486913 0,0637501 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03486913 0,0637017 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03486913 0,06365337 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03486913 0,06360511 ! nucleus localization GO:0051647 19 11 0,000 0,03486913 0,06355692 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03486913 0,06350881 ! bone development GO:0060348 189 91 1,000 0,03492885 0,06356945 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03633981 0,06608736 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03633981 0,06603745 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03705346 0,06728349 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03797874 0,06891164 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03797874 0,06885971 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03797874 0,06880786 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03797874 0,06875609 ! cartilage condensation GO:0001502 20 12 0,000 0,03797874 0,06870439 ! mating GO:0007618 17 12 0,000 0,03797874 0,06865277 ! protein complex disassembly GO:0043241 27 12 0,000 0,03797874 0,06860123 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03797874 0,06854977 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03797874 0,06849838 ! hippocampus development GO:0021766 26 12 0,000 0,03797874 0,06844707 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03797874 0,06839584 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03797874 0,06834468 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03797874 0,0682936 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03797874 0,0682426 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03797874 0,06819167 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03797874 0,06814082 ! drug transport GO:0015893 16 12 0,000 0,03797874 0,06809004 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03797874 0,06803934 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03797874 0,06798872 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03797874 0,06793817 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03797874 0,0678877 ! focal adhesion formation GO:0048041 35 12 0,000 0,03797874 0,0678373 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03797874 0,06778697 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03797874 0,06773672 ! forebrain cell migration GO:0021885 21 12 0,000 0,03797874 0,06768655 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03797874 0,06763645 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03797874 0,06758642 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03797874 0,06753647 ! entry into host cell GO:0030260 32 12 0,000 0,03797874 0,06748659 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,03797874 0,06743678 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03797874 0,06738705 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03797874 0,06733739 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03797874 0,06728781 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03797874 0,06723829 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03797874 0,06718885 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03797874 0,06713949 ! protein homotetramerization GO:0051289 21 12 0,000 0,03797874 0,06709019 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03797874 0,06704097 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03797874 0,06699182 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03797874 0,06694274 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03797874 0,06689373 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03797874 0,0668448 ! cranial nerve development GO:0021545 20 12 0,000 0,03797874 0,06679594 ! fucose catabolic process GO:0019317 22 12 0,000 0,03797874 0,06674714 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03797874 0,06669842 ! histone methylation GO:0016571 26 12 0,000 0,03797874 0,06664977 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03797874 0,06660119 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03797874 0,06655269 ! gland morphogenesis GO:0022612 29 12 0,000 0,03797874 0,06650425 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03797874 0,06645588 ! T cell homeostasis GO:0043029 25 12 0,000 0,03797874 0,06640759 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03797874 0,06635936 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03797874 0,0663112 ! spleen development GO:0048536 22 12 0,000 0,03797874 0,06626312 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03797874 0,0662151 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03797874 0,06616715 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03797874 0,06611928 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03797874 0,06607147 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03797874 0,06602373 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03797874 0,06597606 ! response to cold GO:0009409 17 12 0,000 0,03797874 0,06592846 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03797874 0,06588092 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03797874 0,06583346 ! protein ubiquitination GO:0016567 217 97 1,000 0,03922659 0,06794757 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04107842 0,07110409 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04107842 0,07105297 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04107842 0,07100193 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04107842 0,07095096 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04107842 0,07090006 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04107842 0,07084924 ! lipid localization GO:0010876 28 13 0,000 0,04107842 0,07079849 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,04107842 0,07074781 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04107842 0,0706972 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04107842 0,07064667 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04107842 0,0705962 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04107842 0,07054581 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04107842 0,0704955 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04107842 0,07044525 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04107842 0,07039507 ! methionine metabolic process GO:0006555 27 13 0,000 0,04107842 0,07034497 ! plasma membrane organization GO:0007009 24 13 0,000 0,04107842 0,07029494 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04107842 0,07024498 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04107842 0,07019509 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04107842 0,07014527 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04107842 0,07009552 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04107842 0,07004584 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04107842 0,06999624 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04107842 0,0699467 ! exocrine system development GO:0035272 32 13 0,000 0,04107842 0,06989723 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04107842 0,06984783 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04107842 0,06979851 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04107842 0,06974925 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04107842 0,06970006 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04107842 0,06965094 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04107842 0,06960189 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04107842 0,06955291 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04107842 0,069504 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04107842 0,06945515 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04107842 0,06940638 ! ribosome assembly GO:0042255 17 13 0,000 0,04107842 0,06935767 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04107842 0,06930904 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04107842 0,06926047 ! chromatin silencing GO:0006342 26 13 0,000 0,04107842 0,06921196 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04107842 0,06916353 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04107842 0,06911516 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04107842 0,06906687 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04107842 0,06901863 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04107842 0,06897047 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04107842 0,06892237 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04107842 0,06887435 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04107842 0,06882638 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04107842 0,06877849 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04107842 0,06873066 ! embryonic placenta development GO:0001892 23 13 0,000 0,04107842 0,06868289 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04107842 0,0686352 ! insulin secretion GO:0030073 23 13 0,000 0,04107842 0,06858757 ! actin filament polymerization GO:0030041 24 13 0,000 0,04107842 0,06854 ! acrosome reaction GO:0007340 18 13 0,000 0,04107842 0,06849251 ! rRNA transcription GO:0009303 25 14 0,000 0,04416822 0,07359332 ! lactation GO:0007595 26 14 0,000 0,04416822 0,07354239 ! reproductive cellular process GO:0048610 20 14 0,000 0,04416822 0,07349153 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04416822 0,07344074 ! regulation of S phase GO:0033261 23 14 0,000 0,04416822 0,07339002 ! water transport GO:0006833 21 14 0,000 0,04416822 0,07333937 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04416822 0,07328879 ! non-recombinational repair GO:0000726 25 14 0,000 0,04416822 0,07323828 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04416822 0,07318784 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04416822 0,07313747 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04416822 0,07308717 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04416822 0,07303694 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04416822 0,07298678 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04416822 0,07293668 ! palate development GO:0060021 31 14 0,000 0,04416822 0,07288666 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04416822 0,0728367 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04416822 0,07278681 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04416822 0,07273699 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04416822 0,07268724 ! arginine metabolic process GO:0006525 17 14 0,000 0,04416822 0,07263756 ! regulation of heart rate GO:0002027 24 14 0,000 0,04416822 0,07258794 ! organic alcohol transport GO:0015850 29 14 0,000 0,04416822 0,07253839 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04416822 0,07248891 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04416822 0,0724395 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04416822 0,07239016 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04416822 0,07234088 ! L-amino acid transport GO:0015807 30 14 0,000 0,04416822 0,07229167 ! bone mineralization GO:0030282 17 14 0,000 0,04416822 0,07224252 ! stem cell development GO:0048864 43 14 0,000 0,04416822 0,07219344 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04416822 0,07214443 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04416822 0,07209549 ! cerebellum development GO:0021549 21 14 0,000 0,04416822 0,07204661 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04416822 0,0719978 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04416822 0,07194905 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04416822 0,07190037 ! cofactor transport GO:0051181 26 14 0,000 0,04416822 0,07185176 ! NADP metabolic process GO:0006739 24 14 0,000 0,04416822 0,07180321 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04416822 0,07175473 ! intestinal absorption GO:0050892 25 14 0,000 0,04416822 0,07170631 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04416822 0,07165796 ! oxygen transport GO:0015671 21 14 0,000 0,04416822 0,07160967 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04416822 0,07156145 ! male genitalia development GO:0030539 24 14 0,000 0,04416822 0,07151329 ! regulation of axon extension GO:0030516 37 14 0,000 0,04416822 0,0714652 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04416822 0,07141717 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04724817 0,07634594 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04724817 0,0762947 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,04724817 0,07624353 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04724817 0,07619243 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04724817 0,0761414 ! copper ion transport GO:0006825 20 15 0,000 0,04724817 0,07609043 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04724817 0,07603953 ! sulfate transport GO:0008272 23 15 0,000 0,04724817 0,07598871 ! response to cAMP GO:0051591 22 15 0,000 0,04724817 0,07593795 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04724817 0,07588725 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04724817 0,07583663 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04724817 0,07578607 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04724817 0,07573558 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04724817 0,07568516 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04724817 0,0756348 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04724817 0,07558451 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04724817 0,07553429 ! pituitary gland development GO:0021983 29 15 0,000 0,04724817 0,07548413 ! vesicle coating GO:0006901 33 15 0,000 0,04724817 0,07543404 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04724817 0,07538402 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04724817 0,07533406 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04724817 0,07528417 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04724817 0,07523435 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04724817 0,07518459 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04724817 0,0751349 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04724817 0,07508527 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04724817 0,07503571 ! histone deacetylation GO:0016575 20 15 0,000 0,04724817 0,07498622 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04724817 0,07493679 ! tissue regeneration GO:0042246 26 15 0,000 0,04724817 0,07488742 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04724817 0,07483812 ! water homeostasis GO:0030104 27 15 0,000 0,04724817 0,07478888 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04724817 0,07473971 ! muscle maintenance GO:0046716 26 15 0,000 0,04724817 0,07469061 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04724817 0,07464157 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04724817 0,07459259 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04724817 0,07454367 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04724817 0,07449483 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04724817 0,07444604 ! cell killing GO:0001906 29 15 0,000 0,04724817 0,07439732 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04724817 0,07434866 ! detection of bacterium GO:0016045 18 15 0,000 0,04724817 0,07430007 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04724817 0,07425154 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04724817 0,07420307 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04724817 0,07415467 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04724817 0,07410633 ! peptide hormone processing GO:0016486 23 15 0,000 0,04724817 0,07405805 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0503183 0,0788189 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0503183 0,07876762 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0503183 0,0787164 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0503183 0,07866525 ! bone remodeling GO:0046849 27 16 0,000 0,0503183 0,07861417 ! filopodium assembly GO:0046847 32 16 0,000 0,0503183 0,07856316 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0503183 0,07851221 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0503183 0,07846133 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0503183 0,07841051 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0503183 0,07835976 ! startle response GO:0001964 28 16 0,000 0,0503183 0,07830907 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0503183 0,07825845 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0503183 0,0782079 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0503183 0,07815741 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0503183 0,07810698 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0503183 0,07805663 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0503183 0,07800633 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0503183 0,0779561 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0503183 0,07790594 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0503183 0,07785584 ! response to osmotic stress GO:0006970 25 16 0,000 0,0503183 0,0778058 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0503183 0,07775583 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0503183 0,07770592 ! fructose metabolic process GO:0006000 25 16 0,000 0,0503183 0,07765608 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0503183 0,0776063 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0503183 0,07755658 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0503183 0,07750693 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0503183 0,07745734 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0503183 0,07740782 ! axon cargo transport GO:0008088 43 16 0,000 0,0503183 0,07735836 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0503183 0,07730896 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0503183 0,07725962 ! DNA replication initiation GO:0006270 27 16 0,000 0,0503183 0,07721035 ! neuron recognition GO:0008038 35 16 0,000 0,0503183 0,07716114 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0503183 0,07711199 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0503183 0,07706291 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0503183 0,07701388 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0503183 0,07696492 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0503183 0,07691603 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0503183 0,07686719 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0503183 0,07681842 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0503183 0,07676971 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0503183 0,07672106 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0503183 0,07667247 ! defense response to virus GO:0051607 37 16 0,000 0,0503183 0,07662394 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05337863 0,08123276 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05337863 0,08118141 ! metencephalon development GO:0022037 30 17 0,000 0,05337863 0,08113013 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05337863 0,08107891 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05337863 0,08102775 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05337863 0,08097667 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05337863 0,08092564 ! signal complex assembly GO:0007172 41 17 0,000 0,05337863 0,08087468 ! endothelial cell migration GO:0043542 28 17 0,000 0,05337863 0,08082378 ! inositol metabolic process GO:0006020 28 17 0,000 0,05337863 0,08077295 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05337863 0,08072218 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05337863 0,08067148 ! glial cell development GO:0021782 27 17 0,000 0,05337863 0,08062084 ! limbic system development GO:0021761 36 17 0,000 0,05337863 0,08057026 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05337863 0,08051974 ! adult walking behavior GO:0007628 33 17 0,000 0,05337863 0,08046929 ! heart looping GO:0001947 30 17 0,000 0,05337863 0,0804189 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05337863 0,08036858 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05337863 0,08031832 ! myoblast differentiation GO:0045445 45 17 0,000 0,05337863 0,08026812 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05337863 0,08021798 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05337863 0,08016791 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05337863 0,0801179 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05337863 0,08006795 ! glycine metabolic process GO:0006544 28 17 0,000 0,05337863 0,08001806 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05337863 0,07996824 ! NAD metabolic process GO:0019674 29 17 0,000 0,05337863 0,07991848 ! membrane budding GO:0006900 37 17 0,000 0,05337863 0,07986878 ! DNA integration GO:0015074 29 17 0,000 0,05337863 0,07981914 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05337863 0,07976956 ! regulation of protein binding GO:0043393 33 17 0,000 0,05337863 0,07972004 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05337863 0,07967059 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05337863 0,0796212 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05337863 0,07957187 ! genitalia development GO:0048806 30 17 0,000 0,05337863 0,0795226 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05337863 0,07947339 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05337863 0,07942424 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05337863 0,07937515 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05337863 0,07932612 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05337863 0,07927715 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05337863 0,07922825 ! steroid catabolic process GO:0006706 31 17 0,000 0,05337863 0,0791794 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05337863 0,07913062 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05337863 0,07908189 ! gas transport GO:0015669 25 17 0,000 0,05337863 0,07903323 ! organic cation transport GO:0015695 31 17 0,000 0,05337863 0,07898462 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05337863 0,07893607 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05337863 0,07888759 ! microspike assembly GO:0030035 36 17 0,000 0,05337863 0,07883916 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05337863 0,07879079 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05337863 0,07874248 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05642921 0,08319159 ! neuron maturation GO:0042551 42 18 0,000 0,05642921 0,08314064 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05642921 0,08308976 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05642921 0,08303894 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,05642921 0,08298819 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05642921 0,08293749 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05642921 0,08288686 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05642921 0,08283629 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05642921 0,08278578 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05642921 0,08273533 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05642921 0,08268494 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05642921 0,08263461 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05642921 0,08258435 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05642921 0,08253415 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05642921 0,082484 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05642921 0,08243392 ! response to retinoic acid GO:0032526 26 18 0,000 0,05642921 0,0823839 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05642921 0,08233394 ! response to fungus GO:0009620 21 18 0,000 0,05642921 0,08228404 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05642921 0,0822342 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05642921 0,08218443 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05642921 0,08213471 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05642921 0,08208505 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05642921 0,08203545 ! vitamin transport GO:0051180 27 18 0,000 0,05642921 0,08198591 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05642921 0,08193643 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05642921 0,08188702 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05642921 0,08183766 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05642921 0,08178836 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05642921 0,08173912 ! nerve development GO:0021675 28 18 0,000 0,05642921 0,08168993 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05642921 0,08164081 ! protein secretion GO:0009306 39 19 0,000 0,05947005 0,08598855 ! positive regulation of translation GO:0045727 30 19 0,000 0,05947005 0,0859369 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05947005 0,08588532 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05947005 0,0858338 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05947005 0,08578234 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05947005 0,08573094 ! lipid phosphorylation GO:0046834 35 19 0,000 0,05947005 0,08567961 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05947005 0,08562833 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05947005 0,08557712 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05947005 0,08552597 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05947005 0,08547488 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05947005 0,08542385 ! cerebral cortex development GO:0021987 36 19 0,000 0,05947005 0,08537288 ! pigmentation during development GO:0048066 41 19 0,000 0,05947005 0,08532197 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05947005 0,08527112 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05947005 0,08522034 ! heme metabolic process GO:0042168 36 19 0,000 0,05947005 0,08516961 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05947005 0,08511894 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05947005 0,08506834 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05947005 0,08501779 ! peptide cross-linking GO:0018149 37 19 0,000 0,05947005 0,08496731 ! heart process GO:0003015 30 19 0,000 0,05947005 0,08491688 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05947005 0,08486651 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05947005 0,08481621 ! visual learning GO:0008542 36 19 0,000 0,05947005 0,08476596 ! cellular pigmentation GO:0033059 36 19 0,000 0,05947005 0,08471577 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05947005 0,08466565 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05947005 0,08461558 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05947005 0,08456557 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05947005 0,08451562 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05947005 0,08446573 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05947005 0,0844159 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05947005 0,08436612 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05947005 0,08431641 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05947005 0,08426675 ! cilium assembly GO:0042384 37 19 0,000 0,05947005 0,08421715 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05947005 0,08416761 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0625012 0,08840557 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0625012 0,08835363 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0625012 0,08830175 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0625012 0,08824993 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0625012 0,08819817 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0625012 0,08814647 ! response to vitamin GO:0033273 31 20 0,000 0,0625012 0,08809483 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0625012 0,08804325 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0625012 0,08799174 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0625012 0,08794028 ! response to alkaloid GO:0043279 38 20 0,000 0,0625012 0,08788888 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0625012 0,08783755 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0625012 0,08778627 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0625012 0,08773505 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0625012 0,08768389 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0625012 0,0876328 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0625012 0,08758176 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0625012 0,08753078 ! body fluid secretion GO:0007589 31 20 0,000 0,0625012 0,08747986 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0625012 0,087429 ! peptide secretion GO:0002790 35 20 0,000 0,0625012 0,0873782 ! stem cell differentiation GO:0048863 53 20 0,000 0,0625012 0,08732746 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0625012 0,08727677 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0625012 0,08722615 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0625012 0,08717558 ! sensory perception of pain GO:0019233 30 20 0,000 0,0625012 0,08712507 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0625012 0,08707463 ! diencephalon development GO:0021536 34 20 0,000 0,0625012 0,08702423 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0625012 0,0869739 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0625012 0,08692363 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0625012 0,08687341 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0625012 0,08682325 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0625012 0,08677316 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0625012 0,08672311 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0625012 0,08667313 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0625012 0,0866232 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0625012 0,08657333 ! regulation of glucose import GO:0046324 29 20 0,000 0,0625012 0,08652352 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0625012 0,08647377 ! actin filament-based movement GO:0030048 43 20 0,000 0,0625012 0,08642407 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0625012 0,08637443 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0625012 0,08632484 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0625012 0,08627532 ! regulation of cell killing GO:0031341 42 21 0,000 0,06552267 0,09039424 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06552267 0,09034244 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06552267 0,09029069 ! hormone secretion GO:0046879 38 21 0,000 0,06552267 0,09023901 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06552267 0,09018739 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06552267 0,09013582 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06552267 0,09008431 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06552267 0,09003287 ! ovarian follicle development GO:0001541 35 21 0,000 0,06552267 0,08998148 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06552267 0,08993015 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06552267 0,08987888 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06552267 0,08982766 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06552267 0,08977651 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06552267 0,08972541 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06552267 0,08967437 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06552267 0,08962339 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06552267 0,08957247 ! cytolysis GO:0019835 24 21 0,000 0,06552267 0,08952161 ! vasodilation GO:0042311 39 21 0,000 0,06552267 0,0894708 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06552267 0,08942005 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06552267 0,08936936 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06552267 0,08931873 ! oogenesis GO:0048477 36 21 0,000 0,06552267 0,08926815 ! DNA modification GO:0006304 34 21 0,000 0,06552267 0,08921763 ! collagen fibril organization GO:0030199 59 21 0,000 0,06552267 0,08916717 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06552267 0,08911676 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06552267 0,08906641 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06552267 0,08901612 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06552267 0,08896589 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06552267 0,08891571 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06552267 0,08886559 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06552267 0,08881552 ! collagen catabolic process GO:0030574 28 21 0,000 0,06552267 0,08876551 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06552267 0,08871556 ! gut development GO:0048565 39 21 0,000 0,06552267 0,08866566 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06853451 0,09268917 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06853451 0,0926371 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06853451 0,09258508 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06853451 0,09253313 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06853451 0,09248123 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06853451 0,09242939 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06853451 0,09237761 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06853451 0,09232589 ! regeneration GO:0031099 41 22 0,000 0,06853451 0,09227422 ! keratinization GO:0031424 28 22 0,000 0,06853451 0,09222261 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06853451 0,09217106 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06853451 0,09211957 ! sensory perception of taste GO:0050909 28 22 0,000 0,06853451 0,09206814 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06853451 0,09201676 ! vacuolar transport GO:0007034 36 22 0,000 0,06853451 0,09196544 ! lysosome organization GO:0007040 41 22 0,000 0,06853451 0,09191418 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06853451 0,09186297 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06853451 0,09181182 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06853451 0,09176073 ! fucose metabolic process GO:0006004 39 22 0,000 0,06853451 0,0917097 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06853451 0,09165872 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06853451 0,0916078 ! ureteric bud development GO:0001657 43 22 0,000 0,06853451 0,09155693 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06853451 0,09150612 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06853451 0,09145537 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06853451 0,09140468 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06853451 0,09135404 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06853451 0,09130345 ! sarcomere organization GO:0045214 30 22 0,000 0,06853451 0,09125292 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06853451 0,09120245 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06853451 0,09115204 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06853451 0,09110168 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06853451 0,09105137 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07153674 0,09498753 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07153674 0,09493514 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07153674 0,0948828 ! gluconeogenesis GO:0006094 33 23 0,000 0,07153674 0,09483053 ! viral genome replication GO:0019079 41 23 0,000 0,07153674 0,09477831 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07153674 0,09472614 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07153674 0,09467404 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07153674 0,09462199 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07153674 0,09457 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07153674 0,09451807 ! visual behavior GO:0007632 42 23 0,000 0,07153674 0,09446619 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07153674 0,09441437 ! response to ethanol GO:0045471 46 23 0,000 0,07153674 0,09436261 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07153674 0,09431091 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07153674 0,09425926 ! peroxisome organization GO:0007031 37 23 0,000 0,07153674 0,09420766 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07153674 0,09415613 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07153674 0,09410465 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07153674 0,09405323 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07153674 0,09400186 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07153674 0,09395055 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07153674 0,09389929 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07153674 0,09384809 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07153674 0,09379695 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07153674 0,09374586 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07153674 0,09369483 ! fatty acid transport GO:0015908 44 23 0,000 0,07153674 0,09364385 ! platelet activation GO:0030168 37 23 0,000 0,07153674 0,09359293 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07153674 0,09354207 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07153674 0,09349126 ! hormone transport GO:0009914 40 23 0,000 0,07153674 0,0934405 ! cell-cell recognition GO:0009988 25 23 0,000 0,07153674 0,0933898 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07153674 0,09333916 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07153674 0,09328857 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07153674 0,09323803 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07153674 0,09318755 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07153674 0,09313712 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0745294 0,09698092 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,0745294 0,0969285 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0745294 0,09687614 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0745294 0,09682383 ! vesicle docking GO:0048278 47 24 0,000 0,0745294 0,09677158 ! spinal cord development GO:0021510 47 24 0,000 0,0745294 0,09671938 ! vacuole organization GO:0007033 43 24 0,000 0,0745294 0,09666724 ! digestive system process GO:0022600 39 24 0,000 0,0745294 0,09661516 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0745294 0,09656313 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0745294 0,09651116 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0745294 0,09645924 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0745294 0,09640738 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0745294 0,09635558 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0745294 0,09630383 ! membrane depolarization GO:0051899 39 24 0,000 0,0745294 0,09625214 ! pallium development GO:0021543 49 24 0,000 0,0745294 0,0962005 ! pentose metabolic process GO:0019321 35 24 0,000 0,0745294 0,09614892 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0745294 0,09609739 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0745294 0,09604592 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0745294 0,0959945 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0745294 0,09594314 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0745294 0,09589183 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0745294 0,09584058 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0745294 0,09578939 ! regulation of amine transport GO:0051952 40 24 0,000 0,0745294 0,09573824 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0775125 0,09951712 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0775125 0,09946405 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0775125 0,09941103 ! phototransduction GO:0007602 33 25 0,000 0,0775125 0,09935806 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0775125 0,09930516 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,0775125 0,09925231 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0775125 0,09919951 ! receptor metabolic process GO:0043112 46 25 0,000 0,0775125 0,09914678 ! chromosome condensation GO:0030261 45 25 0,000 0,0775125 0,09909409 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0775125 0,09904147 ! neural crest cell development GO:0014032 54 25 0,000 0,0775125 0,0989889 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0775125 0,09893638 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0775125 0,09888393 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0775125 0,09883152 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0775125 0,09877918 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0775125 0,09872688 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0775125 0,09867465 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,0775125 0,09862247 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0775125 0,09857034 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0775125 0,09851827 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0775125 0,09846625 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0775125 0,09841429 ! telomere organization GO:0032200 43 25 0,000 0,0775125 0,09836239 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0775125 0,09831054 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0775125 0,09825874 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08048609 0,10197448 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08048609 0,10192081 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08048609 0,1018672 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08048609 0,10181364 ! initiation of viral infection GO:0019059 57 26 0,000 0,08048609 0,10176014 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08048609 0,10170669 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08048609 0,1016533 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08048609 0,10159997 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08048609 0,10154669 ! molting cycle process GO:0022404 50 26 0,000 0,08048609 0,10149347 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,08048609 0,10144031 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08048609 0,1013872 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08048609 0,10133414 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,08048609 0,10128114 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08048609 0,1012282 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08048609 0,10117531 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08048609 0,10112248 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08048609 0,1010697 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08048609 0,10101698 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08048609 0,10096431 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08048609 0,1009117 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08048609 0,10085914 ! blastocyst development GO:0001824 49 26 0,000 0,08048609 0,10080663 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08048609 0,10075419 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08048609 0,10070179 ! neuron fate commitment GO:0048663 48 27 0,000 0,0834502 0,10435612 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0834502 0,10430191 ! iron ion transport GO:0006826 59 27 0,000 0,0834502 0,10424776 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0834502 0,10419366 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0834502 0,10413962 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0834502 0,10408563 ! fat cell differentiation GO:0045444 50 27 0,000 0,0834502 0,1040317 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0834502 0,10397782 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0834502 0,10392401 ! autophagy GO:0006914 41 27 0,000 0,0834502 0,10387024 ! male gonad development GO:0008584 44 27 0,000 0,0834502 0,10381653 ! response to toxin GO:0009636 47 27 0,000 0,0834502 0,10376288 ! primary neural tube formation GO:0014020 51 27 0,000 0,0834502 0,10370929 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0834502 0,10365575 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0834502 0,10360226 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0834502 0,10354883 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0834502 0,10349545 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0834502 0,10344213 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0834502 0,10338887 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08640485 0,10699437 ! circadian rhythm GO:0007623 50 28 0,000 0,08640485 0,10693933 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08640485 0,10688435 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08640485 0,10682942 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08640485 0,10677456 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08640485 0,10671974 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08640485 0,10666499 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08640485 0,10661029 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08640485 0,10655564 ! synaptogenesis GO:0007416 42 28 0,000 0,08640485 0,10650105 ! lipid oxidation GO:0034440 43 28 0,000 0,08640485 0,10644652 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08640485 0,10639205 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08935007 0,10996228 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08935007 0,10990606 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08935007 0,1098499 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08935007 0,1097938 ! catechol metabolic process GO:0009712 54 29 0,000 0,08935007 0,10973775 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08935007 0,10968176 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08935007 0,10962583 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08935007 0,10956996 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08935007 0,10951414 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08935007 0,10945838 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08935007 0,10940268 ! cell fate determination GO:0001709 60 29 0,000 0,08935007 0,10934703 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08935007 0,10929144 ! detection of light stimulus GO:0009583 38 29 0,000 0,08935007 0,1092359 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08935007 0,10918043 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08935007 0,109125 ! tissue homeostasis GO:0001894 48 29 0,000 0,08935007 0,10906964 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08935007 0,10901433 ! phenol metabolic process GO:0018958 55 30 0,000 0,09228589 0,1125392 ! zinc ion transport GO:0006829 45 30 0,000 0,09228589 0,11248219 ! membrane docking GO:0022406 61 30 0,000 0,09228589 0,11242524 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09228589 0,11236834 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09228589 0,11231151 ! acute-phase response GO:0006953 49 30 0,000 0,09228589 0,11225473 ! myofibril assembly GO:0030239 47 30 0,000 0,09228589 0,112198 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09228589 0,11214134 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09228589 0,11208473 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09228589 0,11202818 ! phospholipid transport GO:0015914 51 30 0,000 0,09228589 0,11197168 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09228589 0,11191525 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09228589 0,11185887 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09228589 0,11180254 ! eye morphogenesis GO:0048592 60 30 0,000 0,09228589 0,11174628 ! response to heat GO:0009408 50 30 0,000 0,09228589 0,11169006 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09521234 0,11517391 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09521234 0,11511603 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09521234 0,11505821 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09521234 0,11500045 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09521234 0,11494275 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09521234 0,11488511 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09521234 0,11482752 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09521234 0,11476999 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09521234 0,11471252 ! ovulation cycle process GO:0022602 49 31 0,000 0,09521234 0,11465511 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09521234 0,11459775 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09521234 0,11454045 ! peptide transport GO:0015833 55 31 0,000 0,09521234 0,11448321 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09521234 0,11442602 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09521234 0,1143689 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09521234 0,11431183 ! mesoderm formation GO:0001707 69 31 0,000 0,09521234 0,11425481 ! natural killer cell activation GO:0030101 45 31 0,000 0,09521234 0,11419786 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09521234 0,11414096 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09521234 0,11408411 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09521234 0,11402733 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09521234 0,1139706 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09521234 0,11391392 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09812946 0,11734567 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09812946 0,11728738 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09812946 0,11722914 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09812946 0,11717096 ! cholesterol transport GO:0030301 56 32 0,000 0,09812946 0,11711284 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09812946 0,11705478 ! spliceosome assembly GO:0000245 67 32 0,000 0,09812946 0,11699677 ! spindle organization GO:0007051 46 32 0,000 0,09812946 0,11693882 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09812946 0,11688093 ! metanephros development GO:0001656 74 32 0,000 0,09812946 0,1168231 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09812946 0,11676532 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09812946 0,11670761 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09812946 0,11664994 ! muscle cell development GO:0055001 49 32 0,000 0,09812946 0,11659234 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09812946 0,11653479 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09812946 0,1164773 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09812946 0,11641987 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09812946 0,11636249 ! ovulation cycle GO:0042698 51 32 0,000 0,09812946 0,11630517 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09812946 0,1162479 ! hindbrain development GO:0030902 61 32 0,000 0,09812946 0,11619069 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09812946 0,11613354 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09812946 0,11607644 ! gene silencing GO:0016458 65 32 0,000 0,09812946 0,1160194 ! post-embryonic development GO:0009791 69 33 0,000 0,10103727 0,11939866 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10103727 0,11934005 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10103727 0,11928149 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10103727 0,11922299 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10103727 0,11916455 ! cell fate specification GO:0001708 52 33 0,000 0,10103727 0,11910616 ! sterol transport GO:0015918 57 33 0,000 0,10103727 0,11904783 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10103727 0,11898956 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10103727 0,11893135 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10103727 0,11887319 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10103727 0,11881509 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,1039358 0,12216392 ! glial cell differentiation GO:0010001 63 34 0,000 0,1039358 0,12210427 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,1039358 0,12204468 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,1039358 0,12198514 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,1039358 0,12192567 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,1039358 0,12186625 ! mismatch repair GO:0006298 46 34 0,000 0,1039358 0,12180689 ! spermatid development GO:0007286 63 34 0,000 0,1039358 0,12174758 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,1039358 0,12168834 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,1039358 0,12162915 ! placenta development GO:0001890 53 34 0,000 0,1039358 0,12157002 ! regulation of muscle development GO:0048634 70 35 0,000 0,10682508 0,1248888 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10682508 0,12482814 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10682508 0,12476755 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10682508 0,12470701 ! odontogenesis GO:0042476 66 35 0,000 0,10682508 0,12464653 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10682508 0,12458611 ! female gonad development GO:0008585 58 35 0,000 0,10682508 0,12452575 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10682508 0,12446545 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10682508 0,1244052 ! cytokine production GO:0001816 59 35 0,000 0,10682508 0,12434502 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10682508 0,12428489 ! neural tube formation GO:0001841 67 35 0,000 0,10682508 0,12422482 ! vesicle localization GO:0051648 64 35 0,000 0,10682508 0,12416481 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10970514 0,12745078 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10970514 0,12738927 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10970514 0,12732782 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10970514 0,12726643 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10970514 0,1272051 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10970514 0,12714382 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10970514 0,12708261 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10970514 0,12702145 ! aerobic respiration GO:0009060 55 36 0,000 0,10970514 0,12696035 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10970514 0,12689931 ! embryonic organ development GO:0048568 57 36 0,000 0,10970514 0,12683833 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10970514 0,12677741 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11257601 0,13003259 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11257601 0,12997019 ! meiosis I GO:0007127 65 37 0,000 0,11257601 0,12990786 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11257601 0,12984558 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11257601 0,12978337 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11257601 0,12972121 ! organic anion transport GO:0015711 68 37 0,000 0,11257601 0,12965911 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11257601 0,12959707 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11257601 0,12953509 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11257601 0,12947318 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,11257601 0,12941132 ! pigment metabolic process GO:0042440 80 37 0,000 0,11257601 0,12934951 ! spermatid differentiation GO:0048515 66 37 0,000 0,11257601 0,12928777 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11543772 0,13251104 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11543772 0,13244785 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11543772 0,13238472 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11543772 0,13232165 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11543772 0,13225864 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11543772 0,13219569 ! lipid homeostasis GO:0055088 67 38 0,000 0,11543772 0,1321328 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11543772 0,13206997 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11543772 0,1320072 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11543772 0,13194449 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11543772 0,13188184 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11543772 0,13181924 ! glucan metabolic process GO:0044042 62 38 0,000 0,11543772 0,13175671 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11829029 0,13494852 ! learning GO:0007612 77 39 0,000 0,11829029 0,13488457 ! ear morphogenesis GO:0042471 60 39 0,000 0,11829029 0,13482067 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11829029 0,13475684 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11829029 0,13469306 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11829029 0,13462935 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11829029 0,13456569 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11829029 0,1345021 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11829029 0,13443856 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,12113376 0,1376052 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,12113376 0,13754027 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,12113376 0,13747539 ! feeding behavior GO:0007631 59 40 0,000 0,12113376 0,13741057 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,12113376 0,13734582 ! mesenchymal cell development GO:0014031 87 40 0,000 0,12113376 0,13728112 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,12113376 0,13721649 ! cytokinesis GO:0000910 72 40 0,000 0,12113376 0,13715192 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12396815 0,1402951 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12396815 0,14022914 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12396815 0,14016324 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12396815 0,1400974 ! female gamete generation GO:0007292 61 41 0,000 0,12396815 0,14003163 ! polyol metabolic process GO:0019751 66 41 0,000 0,12396815 0,13996592 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1267935 0,14308872 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,1267935 0,14302164 ! regulation of tube size GO:0035150 71 42 0,000 0,1267935 0,14295462 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1267935 0,14288766 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1267935 0,14282076 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1267935 0,14275393 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1267935 0,14268716 ! neuron migration GO:0001764 79 42 0,000 0,1267935 0,14262046 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1267935 0,14255381 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12960982 0,14565214 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12960982 0,14558414 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12960982 0,14551621 ! glucose transport GO:0015758 65 43 0,000 0,12960982 0,14544834 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12960982 0,14538053 ! neural tube development GO:0021915 77 43 0,000 0,12960982 0,14531278 ! striated muscle contraction GO:0006941 77 43 0,000 0,12960982 0,1452451 ! phagocytosis GO:0006909 90 43 0,000 0,12960982 0,14517748 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12960982 0,14510993 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13241716 0,14818404 ! hexose transport GO:0008645 67 44 0,000 0,13241716 0,14811515 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13241716 0,14804632 ! male sex differentiation GO:0046661 76 44 0,000 0,13241716 0,14797756 ! biopolymer methylation GO:0043414 84 44 0,000 0,13241716 0,14790886 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13241716 0,14784023 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13241716 0,14777166 ! developmental growth GO:0048589 82 44 0,000 0,13241716 0,14770315 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13521554 0,15075467 ! glycolysis GO:0006096 65 45 0,000 0,13521554 0,15068484 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13521554 0,15061508 ! leukocyte migration GO:0050900 68 45 0,000 0,13521554 0,15054539 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13521554 0,15047575 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13521554 0,15040619 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13521554 0,15033668 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13521554 0,15026724 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13521554 0,15019787 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13521554 0,15012856 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13521554 0,15005931 ! cell growth GO:0016049 84 45 0,000 0,13521554 0,14999012 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13800498 0,15301381 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,13800498 0,15294333 ! pigmentation GO:0043473 100 46 0,000 0,13800498 0,15287292 ! positive regulation of defense response GO:0031349 76 47 0,000 0,14078551 0,15588125 ! response to calcium ion GO:0051592 81 47 0,000 0,14078551 0,15580954 ! endosome transport GO:0016197 108 47 0,000 0,14078551 0,15573791 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14078551 0,15566634 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,14078551 0,15559483 ! methylation GO:0032259 90 47 0,000 0,14078551 0,15552339 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14355717 0,15851242 ! cellular component disassembly GO:0022411 86 48 0,000 0,14355717 0,15843971 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14355717 0,15836706 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14355717 0,15829448 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14355717 0,15822197 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,14355717 0,15814952 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14631998 0,1611194 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,14631998 0,16104569 ! regulation of ion transport GO:0043269 77 49 0,000 0,14631998 0,16097205 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,14631998 0,16089848 ! peptide metabolic process GO:0006518 76 49 0,000 0,14631998 0,16082498 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14631998 0,16075154 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14631998 0,16067818 ! endocrine system development GO:0035270 104 49 0,000 0,14631998 0,16060487 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,14631998 0,16053164 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14631998 0,16045847 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14631998 0,16038537 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14631998 0,16031233 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,14907397 0,16325534 ! neuromuscular process GO:0050905 99 50 0,000 0,14907397 0,16318107 ! inner ear development GO:0048839 79 50 0,000 0,14907397 0,16310686 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14907397 0,16303272 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14907397 0,16295865 ! viral infectious cycle GO:0019058 99 51 0,000 0,15181917 0,16588416 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,15181917 0,16580886 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15181917 0,16573363 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15181917 0,16565847 ! excretion GO:0007588 83 51 0,000 0,15181917 0,16558337 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,15181917 0,16550835 ! chromatin remodeling GO:0006338 109 51 0,000 0,15181917 0,16543339 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15181917 0,1653585 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15181917 0,16528368 ! vesicle organization GO:0016050 107 51 0,000 0,15181917 0,16520892 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15181917 0,16513423 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1545556 0,16803469 ! membrane fusion GO:0006944 110 52 0,000 0,1545556 0,1679588 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1545556 0,16788297 ! amino acid activation GO:0043038 92 52 0,000 0,1545556 0,16780721 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,1545556 0,16773152 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1572833 0,17061479 ! RNA catabolic process GO:0006401 93 53 0,000 0,1572833 0,1705379 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1572833 0,17046109 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1572833 0,17038434 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,1572833 0,17030765 ! cell maturation GO:0048469 100 53 0,000 0,1572833 0,17023104 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,1572833 0,1701545 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,16000228 0,17301819 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16000228 0,17294047 ! cell recognition GO:0008037 85 54 0,000 0,16000228 0,17286281 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16000228 0,17278523 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16000228 0,17270771 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16000228 0,17263026 ! chloride transport GO:0006821 90 55 0,000 0,16271258 0,17547578 ! glucose catabolic process GO:0006007 82 55 0,000 0,16271258 0,17539716 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,16271258 0,17531861 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16271258 0,17524014 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,16271258 0,17516173 ! gastrulation GO:0007369 112 55 0,000 0,16271258 0,17508339 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,16271258 0,17500513 ! RNA elongation GO:0006354 79 55 0,000 0,16271258 0,17492693 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,16271258 0,1748488 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16541423 0,1776726 ! sensory perception of smell GO:0007608 80 56 0,000 0,16541423 0,17759332 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16541423 0,17751411 ! proton transport GO:0015992 94 56 0,000 0,16541423 0,17743497 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16541423 0,17735589 ! lipid modification GO:0030258 97 57 0,000 0,16810724 0,18016304 ! hydrogen transport GO:0006818 97 58 0,000 0,17079166 0,18295848 ! adult behavior GO:0030534 99 58 0,000 0,17079166 0,18287705 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17346751 0,18565962 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17346751 0,18557707 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17346751 0,18549459 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17346751 0,18541218 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17346751 0,18532985 ! DNA catabolic process GO:0006308 86 59 0,000 0,17346751 0,18524759 ! establishment of organelle localization GO:0051656 109 59 0,000 0,17346751 0,1851654 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1761348 0,1879292 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1761348 0,1878459 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1761348 0,18776267 ! camera-type eye development GO:0043010 116 60 0,000 0,1761348 0,18767951 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1761348 0,18759643 ! kidney development GO:0001822 122 60 0,000 0,1761348 0,18751342 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17879358 0,19025978 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,17879358 0,19017567 ! mesoderm development GO:0007498 119 61 0,000 0,17879358 0,19009163 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17879358 0,19000767 ! ear development GO:0043583 103 62 0,000 0,18144387 0,19273905 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,18144387 0,19265399 ! gonad development GO:0008406 98 62 0,000 0,18144387 0,19256901 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,18408569 0,19528667 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,18408569 0,19520061 ! detection of external stimulus GO:0009581 91 63 0,000 0,18408569 0,19511461 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,18408569 0,1950287 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18671907 0,19773156 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18671907 0,19764456 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18671907 0,19755765 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18671907 0,19747081 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18671907 0,19738405 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18934405 0,20007105 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18934405 0,19998322 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18934405 0,19989547 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,18934405 0,1998078 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,18934405 0,1997202 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,19196063 0,20239145 ! actin filament organization GO:0007015 148 66 0,000 0,19196063 0,20230279 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19196063 0,20221422 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19196063 0,20212572 ! secondary metabolic process GO:0019748 116 66 0,000 0,19196063 0,2020373 ! developmental maturation GO:0021700 116 66 0,000 0,19196063 0,20194896 ! cell projection assembly GO:0030031 120 66 0,000 0,19196063 0,2018607 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,19456886 0,20451406 ! chromosome segregation GO:0007059 113 67 0,000 0,19456886 0,20442475 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,19456886 0,20433552 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,19456886 0,20424637 ! hexose catabolic process GO:0019320 104 67 0,000 0,19456886 0,20415729 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,19456886 0,2040683 ! activation of immune response GO:0002253 105 67 0,000 0,19456886 0,20397938 ! amino acid transport GO:0006865 125 68 0,000 0,19716875 0,20661499 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19716875 0,20652504 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19716875 0,20643517 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19716875 0,20634538 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19716875 0,20625566 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19976034 0,20887587 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19976034 0,20878513 ! urogenital system development GO:0001655 137 69 0,000 0,19976034 0,20869448 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19976034 0,2086039 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19976034 0,2085134 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20234365 0,21111831 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,2049187 0,21371235 ! reproductive structure development GO:0048608 113 71 0,000 0,2049187 0,21361976 ! appendage development GO:0048736 136 71 0,000 0,2049187 0,21352724 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,2049187 0,21343481 ! acute inflammatory response GO:0002526 113 72 0,000 0,20748553 0,21601479 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,20748553 0,21592136 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,20748553 0,21582801 ! carbohydrate transport GO:0008643 110 72 0,000 0,20748553 0,21573474 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,20748553 0,21564155 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,20748553 0,21554844 ! regulation of blood pressure GO:0008217 125 73 0,000 0,21004416 0,21811232 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,21004416 0,21801822 ! fertilization GO:0009566 90 73 0,000 0,21004416 0,21792421 ! transition metal ion transport GO:0000041 126 74 0,000 0,21259461 0,22047527 ! neurotransmitter transport GO:0006836 123 74 0,000 0,21259461 0,22038028 ! meiosis GO:0007126 121 74 0,000 0,21259461 0,22028537 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,21259461 0,22019054 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,21259461 0,22009579 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,21259461 0,22000113 ! eye development GO:0001654 143 74 0,000 0,21259461 0,21990654 ! organelle localization GO:0051640 136 74 0,000 0,21259461 0,21981204 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,21513691 0,2223451 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21513691 0,22224963 ! meiotic cell cycle GO:0051321 122 75 0,000 0,21513691 0,22215425 ! rhythmic process GO:0048511 128 75 0,000 0,21513691 0,22205894 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21767108 0,22457831 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,21767108 0,22448205 ! defense response to bacterium GO:0042742 89 76 0,000 0,21767108 0,22438587 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21767108 0,22428977 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21767108 0,22419376 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,22019716 0,22669849 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,22019716 0,22660153 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,22019716 0,22650465 ! blood coagulation GO:0007596 146 78 0,000 0,22271516 0,22899687 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,22271516 0,22889905 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,22271516 0,22880132 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,22271516 0,22870366 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22522512 0,23118244 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,22522512 0,23108386 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,22522512 0,23098536 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,22522512 0,23088694 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,22772706 0,23335234 ! response to metal ion GO:0010038 140 80 0,000 0,22772706 0,233253 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22772706 0,23315375 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22772706 0,23305457 ! inorganic anion transport GO:0015698 138 80 0,000 0,22772706 0,23295549 ! digestion GO:0007586 112 81 0,000 0,230221 0,2354066 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,230221 0,23530659 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,230221 0,23520668 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,23270697 0,23764557 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,23270697 0,23754475 ! response to nutrient GO:0007584 125 82 0,000 0,23270697 0,23744401 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,23270697 0,23734335 ! regulation of lyase activity GO:0051339 160 83 0,000 0,23518499 0,23976911 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,23765509 0,24218473 ! hemostasis GO:0007599 158 84 0,000 0,23765509 0,2420822 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23765509 0,24197975 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23765509 0,24187739 ! response to unfolded protein GO:0006986 131 85 0,000 0,2401173 0,24428001 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2401173 0,24417676 ! amine biosynthetic process GO:0009309 138 86 0,000 0,24257164 0,24656838 ! response to inorganic substance GO:0010035 153 86 0,000 0,24257164 0,24646426 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24257164 0,24636022 ! tube morphogenesis GO:0035239 176 86 0,000 0,24257164 0,24625627 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24257164 0,24615241 ! amine transport GO:0015837 155 86 0,000 0,24257164 0,24604863 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,24501813 0,24842546 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,24501813 0,24832081 ! cellular respiration GO:0045333 135 88 0,000 0,2474568 0,25068676 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,2474568 0,25058125 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2474568 0,25047583 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2474568 0,2503705 ! cellular defense response GO:0006968 114 89 0,000 0,24988767 0,25272372 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,25231077 0,25506711 ! sex differentiation GO:0007548 145 90 0,000 0,25231077 0,25495998 ! sterol metabolic process GO:0016125 152 91 0,000 0,25472613 0,25729264 ! response to protein stimulus GO:0051789 149 91 0,000 0,25472613 0,25718467 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25472613 0,25707679 ! regulation of defense response GO:0031347 149 92 0,000 0,25713376 0,25939783 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25713376 0,25928911 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25713376 0,25918049 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,25953369 0,26148998 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,25953369 0,26138052 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25953369 0,26127116 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,26192595 0,26356915 ! female pregnancy GO:0007565 164 94 0,000 0,26192595 0,26345896 ! transcription initiation GO:0006352 153 94 0,000 0,26192595 0,26334887 ! forebrain development GO:0030900 188 95 0,000 0,26431056 0,26563543 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,26431056 0,26552452 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26668755 0,2678006 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,26668755 0,26768888 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26668755 0,26757725 ! detection of stimulus GO:0051606 151 96 0,000 0,26668755 0,26746571 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26905694 0,26972958 ! hormone metabolic process GO:0042445 157 97 0,000 0,26905694 0,26961724 ! response to virus GO:0009615 160 98 0,000 0,27141874 0,27187073 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,27141874 0,27175759 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,27141874 0,27164455 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,273773 0,27388683 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,273773 0,273773