pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6151-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! pigmentation GO:0043473 100 46 5,000 1,977E-09 4,757E-06 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 1,601E-07 1,926E-04 ! negative regulation of survival gene product expression GO:0008634 8 5 2,000 1,601E-07 1,284E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,583E-07 3,358E-04 ! cell junction assembly GO:0034329 78 30 3,000 1,029E-06 4,951E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,335E-06 5,353E-04 ! T cell selection GO:0045058 23 9 2,000 1,335E-06 4,588E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,903E-06 5,725E-04 ! protein sumoylation GO:0016925 15 10 2,000 1,903E-06 5,089E-04 ! cell junction organization GO:0034330 86 36 3,000 2,186E-06 5,259E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,612E-06 5,714E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,612E-06 5,238E-04 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 19 12 2,000 3,477E-06 6,435E-04 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 2,000 3,477E-06 5,975E-04 ! regulation of membrane potential GO:0042391 164 93 4,000 4,175E-06 6,696E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 5,434E-06 8,171E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 5,731E-06 8,112E-04 ! T cell differentiation in the thymus GO:0033077 31 14 2,000 5,731E-06 7,661E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 5,731E-06 7,258E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7,151E-06 8,603E-04 ! defense response to virus GO:0051607 37 16 2,000 8,785E-06 1,007E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,065E-05 1,165E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,065E-05 1,114E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,065E-05 1,067E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,275E-05 1,227E-03 ! pigmentation during development GO:0048066 41 19 2,000 1,512E-05 1,399E-03 ! cellular pigmentation GO:0033059 36 19 2,000 1,512E-05 1,347E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,775E-05 1,525E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,775E-05 1,473E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,775E-05 1,424E-03 GO:0010827|regulation of glucose transport, ! regulation of homeostatic process GO:0032844 134 62 3,000 1,968E-05 1,528E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,067E-05 1,554E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,067E-05 1,507E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,067E-05 1,463E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,067E-05 1,421E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 2,389E-05 1,597E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,389E-05 1,554E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,679E-05 1,696E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,743E-05 1,692E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,841E-05 1,709E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,129E-05 1,836E-03 ! regulation of behavior GO:0050795 43 24 2,000 3,129E-05 1,792E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,129E-05 1,751E-03 ! myelination GO:0042552 45 25 2,000 3,549E-05 1,941E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,561E-05 1,904E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 4,004E-05 2,094E-03 GO:0045936|negative regulation of phosphate metabolic process, ! mitochondrial membrane organization GO:0007006 57 27 2,000 4,497E-05 2,302E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 5,027E-05 2,52E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 6,207E-05 3,048E-03 GO:0008366|axon ensheathment, ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 6,42E-05 3,089E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 6,42E-05 3,029E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 6,42E-05 2,97E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 6,42E-05 2,914E-03 ! decidualization GO:0046697 11 5 1,000 6,42E-05 2,86E-03 ! B cell homeostasis GO:0001782 13 5 1,000 6,42E-05 2,808E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 6,42E-05 2,758E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 6,42E-05 2,71E-03 ! negative regulation of transport GO:0051051 153 84 3,000 6,525E-05 2,707E-03 ! mitochondrion organization GO:0007005 148 86 3,000 7,154E-05 2,917E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 7,555E-05 3,03E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 8,296E-05 3,272E-03 GO:0060326|cell chemotaxis, ! thymic T cell selection GO:0045061 12 6 1,000 9,614E-05 3,731E-03 ! neuron apoptosis GO:0051402 9 6 1,000 9,614E-05 3,672E-03 ! neural nucleus development GO:0048857 14 6 1,000 9,614E-05 3,614E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 9,614E-05 3,559E-03 ! maternal placenta development GO:0001893 12 6 1,000 9,614E-05 3,505E-03 ! response to virus GO:0009615 160 98 3,000 1,189E-04 4,27E-03 ! nucleus organization GO:0006997 67 38 2,000 1,271E-04 4,497E-03 ! neuron adhesion GO:0007158 12 7 1,000 1,344E-04 4,685E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,344E-04 4,619E-03 ! organ growth GO:0035265 15 7 1,000 1,344E-04 4,553E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,344E-04 4,49E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,344E-04 4,429E-03 ! axonal fasciculation GO:0007413 18 7 1,000 1,344E-04 4,369E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 1,344E-04 4,311E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 1,344E-04 4,254E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 1,344E-04 4,199E-03 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,374E-04 4,239E-03 ! T cell differentiation GO:0030217 81 41 2,000 1,597E-04 4,864E-03 ! response to reactive oxygen species GO:0000302 67 42 2,000 1,717E-04 5,163E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,789E-04 5,313E-03 ! endothelial cell differentiation GO:0045446 17 8 1,000 1,789E-04 5,248E-03 ! pigment granule organization GO:0048753 16 8 1,000 1,789E-04 5,185E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,789E-04 5,123E-03 ! melanin metabolic process GO:0006582 15 8 1,000 1,789E-04 5,063E-03 ! response to UV-B GO:0010224 16 8 1,000 1,789E-04 5,004E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,789E-04 4,947E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,789E-04 4,89E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,789E-04 4,835E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,842E-04 4,925E-03 ! leukocyte migration GO:0050900 68 45 2,000 2,11E-04 5,58E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 2,296E-04 6,004E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 2,296E-04 5,94E-03 ! behavioral fear response GO:0001662 22 9 1,000 2,296E-04 5,876E-03 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 2,296E-04 5,815E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 2,296E-04 5,754E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 2,296E-04 5,695E-03 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 2,296E-04 5,637E-03 ! regulation of cell division GO:0051302 15 9 1,000 2,296E-04 5,58E-03 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 2,296E-04 5,524E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 2,296E-04 5,469E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 2,403E-04 5,668E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,403E-04 5,613E-03 ! mitochondrial transport GO:0006839 82 48 2,000 2,558E-04 5,918E-03 ! cellular component disassembly GO:0022411 86 48 2,000 2,558E-04 5,862E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,558E-04 5,807E-03 ! regulation of action potential GO:0001508 95 49 2,000 2,72E-04 6,116E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,72E-04 6,06E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,865E-04 6,324E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 2,865E-04 6,267E-03 ! L-serine metabolic process GO:0006563 18 10 1,000 2,865E-04 6,21E-03 ! B cell proliferation GO:0042100 18 10 1,000 2,865E-04 6,155E-03 ! alpha-beta T cell activation GO:0046631 23 10 1,000 2,865E-04 6,1E-03 ! apical protein localization GO:0045176 15 10 1,000 2,865E-04 6,047E-03 ! oocyte development GO:0048599 17 10 1,000 2,865E-04 5,994E-03 ! blastocyst formation GO:0001825 17 10 1,000 2,865E-04 5,943E-03 ! response to nicotine GO:0035094 20 10 1,000 2,865E-04 5,892E-03 ! positive regulation of binding GO:0051099 78 51 2,000 3,063E-04 6,246E-03 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,245E-04 6,561E-03 ! cartilage development GO:0051216 90 52 2,000 3,245E-04 6,506E-03 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 3,433E-04 6,827E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 3,496E-04 6,895E-03 ! melanocyte differentiation GO:0030318 21 11 1,000 3,496E-04 6,838E-03 GO:0050931|pigment cell differentiation, ! negative regulation of ossification GO:0030279 26 11 1,000 3,496E-04 6,783E-03 ! DNA methylation GO:0006306 19 11 1,000 3,496E-04 6,729E-03 GO:0006305|DNA alkylation, ! oocyte differentiation GO:0009994 18 11 1,000 3,496E-04 6,676E-03 ! thymus development GO:0048538 27 11 1,000 3,496E-04 6,623E-03 ! asymmetric protein localization GO:0008105 20 12 1,000 4,188E-04 7,873E-03 ! fear response GO:0042596 26 12 1,000 4,188E-04 7,812E-03 ! gland morphogenesis GO:0022612 29 12 1,000 4,188E-04 7,751E-03 ! T cell homeostasis GO:0043029 25 12 1,000 4,188E-04 7,692E-03 ! spleen development GO:0048536 22 12 1,000 4,188E-04 7,634E-03 ! digestive tract morphogenesis GO:0048546 26 12 1,000 4,188E-04 7,577E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,188E-04 7,52E-03 GO:0042130|negative regulation of T cell proliferation, ! DNA catabolic process GO:0006308 86 59 2,000 4,712E-04 8,398E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 4,942E-04 8,742E-03 ! cell-cell junction assembly GO:0007043 27 13 1,000 4,942E-04 8,678E-03 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 4,942E-04 8,615E-03 ! embryonic placenta development GO:0001892 23 13 1,000 4,942E-04 8,553E-03 ! regulation of heart contraction GO:0008016 110 60 2,000 4,951E-04 8,509E-03 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,951E-04 8,449E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,198E-04 8,807E-03 ! ear development GO:0043583 103 62 2,000 5,452E-04 9,173E-03 ! hair follicle morphogenesis GO:0031069 26 14 1,000 5,756E-04 9,617E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 5,756E-04 9,55E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 5,756E-04 9,485E-03 ! response to gamma radiation GO:0010332 28 14 1,000 5,756E-04 9,42E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 5,756E-04 9,357E-03 ! multicellular organism reproduction GO:0032504 111 64 2,000 5,984E-04 9,663E-03 GO:0048609|reproductive process in a multicellular organism, ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 5,984E-04 9,599E-03 ! actin filament organization GO:0007015 148 66 2,000 6,548E-04 0,01043421 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 6,63E-04 0,01049459 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 6,63E-04 0,010426 ! lymphocyte homeostasis GO:0002260 30 15 1,000 6,63E-04 0,0103583 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 6,843E-04 0,01062194 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 7,565E-04 0,01166693 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 7,565E-04 0,01159261 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 7,565E-04 0,01151924 GO:0031114|regulation of microtubule depolymerization, ! neuron recognition GO:0008038 35 16 1,000 7,565E-04 0,01144679 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 7,565E-04 0,01137525 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 7,565E-04 0,0113046 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 7,565E-04 0,01123482 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 8,441E-04 0,0124602 ! metencephalon development GO:0022037 30 17 1,000 8,559E-04 0,01255669 ! regulation of viral genome replication GO:0045069 28 17 1,000 8,559E-04 0,01248058 ! glycine metabolic process GO:0006544 28 17 1,000 8,559E-04 0,0124054 ! regulation of protein binding GO:0043393 33 17 1,000 8,559E-04 0,01233112 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 8,559E-04 0,01225772 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 8,559E-04 0,01218519 ! axon guidance GO:0007411 139 73 2,000 8,787E-04 0,01243635 ! cell-matrix adhesion GO:0007160 163 75 2,000 9,505E-04 0,01337386 ! lymphocyte differentiation GO:0030098 167 75 2,000 9,505E-04 0,0132961 ! epidermis morphogenesis GO:0048730 40 18 1,000 9,613E-04 0,01336921 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 9,613E-04 0,01329237 ! actin filament bundle formation GO:0051017 42 19 1,000 1,073E-03 0,01474683 ! neuromuscular junction development GO:0007528 34 19 1,000 1,073E-03 0,01466305 ! plasma membrane fusion GO:0045026 28 19 1,000 1,073E-03 0,0145802 ! G1 phase GO:0051318 40 19 1,000 1,073E-03 0,01449829 ! cell-cell junction organization GO:0045216 35 19 1,000 1,073E-03 0,0144173 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,073E-03 0,0143372 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 1,105E-03 0,01468891 ! response to metal ion GO:0010038 140 80 2,000 1,146E-03 0,01514959 ! T cell activation GO:0042110 168 81 2,000 1,188E-03 0,01561768 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 1,188E-03 0,0155328 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 2,000 1,188E-03 0,01544884 ! cell-substrate adhesion GO:0031589 171 81 2,000 1,188E-03 0,01536578 ! regulation of neuron differentiation GO:0045664 167 81 2,000 1,188E-03 0,01528361 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,19E-03 0,0152271 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,19E-03 0,01514653 ! response to drug GO:0042493 143 82 2,000 1,231E-03 0,01558496 ! response to oxygen levels GO:0070482 176 83 2,000 1,275E-03 0,01605533 ! ovarian follicle development GO:0001541 35 21 1,000 1,313E-03 0,01645205 ! cell aging GO:0007569 44 21 1,000 1,313E-03 0,01636681 ! oogenesis GO:0048477 36 21 1,000 1,313E-03 0,01628245 ! DNA modification GO:0006304 34 21 1,000 1,313E-03 0,01619895 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,313E-03 0,0161163 ! response to cytokine stimulus GO:0034097 63 21 1,000 1,313E-03 0,01603449 ! collagen catabolic process GO:0030574 28 21 1,000 1,313E-03 0,01595351 ! gut development GO:0048565 39 21 1,000 1,313E-03 0,01587334 ! one-carbon metabolic process GO:0006730 154 85 2,000 1,365E-03 0,01642225 ! response to inorganic substance GO:0010035 153 86 2,000 1,412E-03 0,01690021 ! glutamate signaling pathway GO:0007215 41 22 1,000 1,442E-03 0,0171729 ! regeneration GO:0031099 41 22 1,000 1,442E-03 0,0170883 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,442E-03 0,01700453 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 1,442E-03 0,01692159 ! ureteric bud development GO:0001657 43 22 1,000 1,442E-03 0,01683944 ! renal system process GO:0003014 41 22 1,000 1,442E-03 0,01675809 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 1,442E-03 0,01667752 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,442E-03 0,01659773 ! positive regulation of protein modification process GO:0031401 136 88 2,000 1,508E-03 0,01728159 ! regulation of DNA binding GO:0051101 155 88 2,000 1,508E-03 0,01719969 ! gland development GO:0048732 206 88 2,000 1,508E-03 0,01711856 ! regulation of cell adhesion GO:0030155 212 89 2,000 1,558E-03 0,01760032 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,576E-03 0,01772437 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,576E-03 0,01764193 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 1,576E-03 0,01756025 ! regulation of viral reproduction GO:0050792 38 23 1,000 1,576E-03 0,01747933 ! synaptic vesicle transport GO:0048489 46 23 1,000 1,576E-03 0,01739915 ! platelet activation GO:0030168 37 23 1,000 1,576E-03 0,0173197 ! regulation of defense response GO:0031347 149 92 2,000 1,714E-03 0,01874022 ! multicellular organismal response to stress GO:0033555 49 24 1,000 1,717E-03 0,01869226 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 1,717E-03 0,01860806 ! lymphocyte proliferation GO:0046651 48 24 1,000 1,717E-03 0,01852462 ! leukocyte homeostasis GO:0001776 44 24 1,000 1,717E-03 0,01844192 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,767E-03 0,01889997 ! female pregnancy GO:0007565 164 94 2,000 1,822E-03 0,01940116 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,863E-03 0,01974794 ! vasculogenesis GO:0001570 46 25 1,000 1,863E-03 0,01966132 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,878E-03 0,01973525 ! leukocyte differentiation GO:0002521 202 96 2,000 1,935E-03 0,02024626 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 1,994E-03 0,02076399 ! regulation of protein localization GO:0032880 176 97 2,000 1,994E-03 0,02067449 ! molting cycle process GO:0022404 50 26 1,000 2,015E-03 0,02080823 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! insulin receptor signaling pathway GO:0008286 64 26 1,000 2,015E-03 0,02071931 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,015E-03 0,02063114 ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,015E-03 0,02054372 ! blastocyst development GO:0001824 49 26 1,000 2,015E-03 0,02045704 ! leukocyte proliferation GO:0070661 52 26 1,000 2,015E-03 0,02037108 GO:0032943|mononuclear cell proliferation, ! interphase GO:0051325 213 98 2,000 2,053E-03 0,02066492 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,173E-03 0,02178137 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 2,173E-03 0,02169099 ! male gonad development GO:0008584 44 27 1,000 2,173E-03 0,02160136 ! response to toxin GO:0009636 47 27 1,000 2,173E-03 0,02151246 ! regulation of chromosome organization GO:0033044 42 27 1,000 2,173E-03 0,0214243 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,173E-03 0,02133685 ! dendrite development GO:0016358 59 28 1,000 2,336E-03 0,02284692 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,336E-03 0,02275442 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 2,505E-03 0,02430116 ! response to organic cyclic substance GO:0014070 55 29 1,000 2,505E-03 0,02420357 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 2,505E-03 0,02410675 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 2,505E-03 0,02401071 ! tissue homeostasis GO:0001894 48 29 1,000 2,505E-03 0,02391543 GO:0048871|multicellular organismal homeostasis, ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 2,679E-03 0,02548023 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,679E-03 0,02537992 ! response to heat GO:0009408 50 30 1,000 2,679E-03 0,02528039 ! collagen metabolic process GO:0032963 45 31 1,000 2,859E-03 0,02687384 ! ovulation cycle process GO:0022602 49 31 1,000 2,859E-03 0,02676927 ! iron ion homeostasis GO:0055072 54 31 1,000 2,859E-03 0,02666551 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 2,859E-03 0,02656256 ! response to hydrogen peroxide GO:0042542 50 32 1,000 3,045E-03 0,02817781 ! metanephros development GO:0001656 74 32 1,000 3,045E-03 0,02806985 ! response to ionizing radiation GO:0010212 65 32 1,000 3,045E-03 0,02796271 ! response to mechanical stimulus GO:0009612 57 32 1,000 3,045E-03 0,02785639 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,045E-03 0,02775087 ! ovulation cycle GO:0042698 51 32 1,000 3,045E-03 0,02764615 ! peripheral nervous system development GO:0007422 64 32 1,000 3,045E-03 0,02754222 ! hindbrain development GO:0030902 61 32 1,000 3,045E-03 0,02743907 ! DNA damage checkpoint GO:0000077 71 33 1,000 3,236E-03 0,02905229 ! post-embryonic development GO:0009791 69 33 1,000 3,236E-03 0,02894429 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,236E-03 0,02883709 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 3,433E-03 0,03047595 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 3,433E-03 0,03036391 ! placenta development GO:0001890 53 34 1,000 3,433E-03 0,03025269 ! regulation of muscle development GO:0048634 70 35 1,000 3,635E-03 0,03191631 ! female gonad development GO:0008585 58 35 1,000 3,635E-03 0,03180026 ! regulation of microtubule-based process GO:0032886 78 35 1,000 3,635E-03 0,03168504 ! positive regulation of cell development GO:0010720 80 36 1,000 3,842E-03 0,03337259 ! DNA integrity checkpoint GO:0031570 75 36 1,000 3,842E-03 0,03325254 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,842E-03 0,03313336 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 4,055E-03 0,03484401 ! regulation of protein stability GO:0031647 73 37 1,000 4,055E-03 0,03472001 ! pigment metabolic process GO:0042440 80 37 1,000 4,055E-03 0,03459689 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 4,055E-03 0,03447464 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 4,273E-03 0,03620195 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 4,273E-03 0,03607492 GO:0046660|female sex differentiation, ! mammary gland development GO:0030879 86 39 1,000 4,497E-03 0,03782947 ! learning GO:0007612 77 39 1,000 4,497E-03 0,03769766 ! ear morphogenesis GO:0042471 60 39 1,000 4,497E-03 0,03756677 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 4,497E-03 0,03743678 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 4,726E-03 0,03920649 ! mesenchymal cell development GO:0014031 87 40 1,000 4,726E-03 0,03907176 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,96E-03 0,04086728 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,96E-03 0,04072781 ! female gamete generation GO:0007292 61 41 1,000 4,96E-03 0,04058928 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 5,199E-03 0,04240426 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 5,199E-03 0,042261 ! neuron migration GO:0001764 79 42 1,000 5,199E-03 0,04211871 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 5,199E-03 0,04197737 ! glucose transport GO:0015758 65 43 1,000 5,444E-03 0,04380549 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 5,444E-03 0,04365947 ! hexose transport GO:0008645 67 44 1,000 5,694E-03 0,04551143 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 5,694E-03 0,04536073 ! biopolymer methylation GO:0043414 84 44 1,000 5,694E-03 0,04521102 ! B cell differentiation GO:0030183 107 44 1,000 5,694E-03 0,0450623 ! developmental growth GO:0048589 82 44 1,000 5,694E-03 0,04491456 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 5,949E-03 0,04677282 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 5,949E-03 0,04662046 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 6,209E-03 0,04850131 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 6,209E-03 0,04834435 ! negative regulation of cell migration GO:0030336 115 46 1,000 6,209E-03 0,0481884 ! response to insulin stimulus GO:0032868 95 46 1,000 6,209E-03 0,04803345 ! response to calcium ion GO:0051592 81 47 1,000 6,474E-03 0,04992513 ! JNK cascade GO:0007254 91 47 1,000 6,474E-03 0,04976562 ! methylation GO:0032259 90 47 1,000 6,474E-03 0,04960713 ! activation of caspase activity GO:0006919 84 48 1,000 6,744E-03 0,05151468 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,744E-03 0,05135165 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 6,744E-03 0,05118966 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 7,02E-03 0,05311255 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 7,02E-03 0,05294605 ! response to temperature stimulus GO:0009266 76 49 1,000 7,02E-03 0,05278059 ! detection of abiotic stimulus GO:0009582 74 49 1,000 7,02E-03 0,05261617 ! regulation of ossification GO:0030278 117 50 1,000 7,3E-03 0,05454837 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 7,3E-03 0,05437949 ! negative regulation of immune system process GO:0002683 95 50 1,000 7,3E-03 0,05421165 ! response to estrogen stimulus GO:0043627 93 51 1,000 7,586E-03 0,05615819 ! chromatin remodeling GO:0006338 109 51 1,000 7,586E-03 0,05598593 ! vesicle organization GO:0016050 107 51 1,000 7,586E-03 0,05581472 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 7,586E-03 0,05564455 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 7,586E-03 0,05547542 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 7,586E-03 0,05530731 ! regulation of angiogenesis GO:0045765 114 52 1,000 7,876E-03 0,05725148 ! membrane fusion GO:0006944 110 52 1,000 7,876E-03 0,05707904 ! positive regulation of growth GO:0045927 90 52 1,000 7,876E-03 0,05690763 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 7,876E-03 0,05673725 ! synapse organization GO:0050808 85 52 1,000 7,876E-03 0,05656788 ! response to UV GO:0009411 104 53 1,000 8,172E-03 0,05851486 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 8,472E-03 0,06048548 ! cell recognition GO:0008037 85 54 1,000 8,472E-03 0,06030653 ! positive regulation of caspase activity GO:0043280 95 55 1,000 8,777E-03 0,06229504 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 1,000 8,777E-03 0,06211182 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 8,777E-03 0,06192967 ! negative regulation of cell motion GO:0051271 134 55 1,000 8,777E-03 0,06174859 ! skeletal muscle fiber development GO:0048741 111 56 1,000 9,087E-03 0,06374391 ! regulation of DNA replication GO:0006275 101 56 1,000 9,087E-03 0,06355861 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 9,402E-03 0,06557095 ! regulation of bone remodeling GO:0046850 137 57 1,000 9,402E-03 0,06538144 ! muscle fiber development GO:0048747 112 57 1,000 9,402E-03 0,06519302 ! positive regulation of cell migration GO:0030335 126 57 1,000 9,402E-03 0,06500569 ! regulation of intracellular transport GO:0032386 101 57 1,000 9,402E-03 0,06481942 ! regulation of tissue remodeling GO:0034103 140 58 1,000 9,722E-03 0,06683258 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0100467 0,06886716 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,0100467 0,06867151 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,01037607 0,07072188 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01037607 0,0705221 ! kidney development GO:0001822 122 60 1,000 0,01037607 0,07032345 ! gonad development GO:0008406 98 62 1,000 0,01104901 0,07467395 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,01139254 0,07677998 ! detection of external stimulus GO:0009581 91 63 1,000 0,01139254 0,07656552 ! single fertilization GO:0007338 75 64 1,000 0,01174074 0,07868584 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,01174074 0,07846727 ! germ cell development GO:0007281 118 65 1,000 0,01209358 0,08060153 ! secondary metabolic process GO:0019748 116 66 1,000 0,01245104 0,08275471 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01271912 0,08430358 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01271912 0,08407197 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01271912 0,08384164 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01271912 0,08361256 ! neuron fate determination GO:0048664 7 5 0,000 0,01271912 0,08338474 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01271912 0,08315815 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01271912 0,08293279 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01271912 0,08270864 ! polyol transport GO:0015791 12 5 0,000 0,01271912 0,08248571 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01271912 0,08226397 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01271912 0,08204343 ! response to superoxide GO:0000303 10 5 0,000 0,01271912 0,08182406 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01271912 0,08160586 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01271912 0,08138882 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01271912 0,08117294 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01271912 0,0809582 ! female meiosis GO:0007143 7 5 0,000 0,01271912 0,08074459 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01271912 0,0805321 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01271912 0,08032073 ! cobalt ion transport GO:0006824 11 5 0,000 0,01271912 0,08011047 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01271912 0,0799013 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01271912 0,07969322 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01271912 0,07948623 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01271912 0,07928031 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01271912 0,07907545 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01271912 0,07887164 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01271912 0,07866889 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01271912 0,07846717 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01271912 0,07826649 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01271912 0,07806683 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01271912 0,07786819 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01271912 0,07767055 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01271912 0,07747392 ! negative chemotaxis GO:0050919 14 5 0,000 0,01271912 0,07727828 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01271912 0,07708362 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01271912 0,07688995 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01271912 0,07669724 ! behavioral response to pain GO:0048266 9 5 0,000 0,01271912 0,0765055 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01271912 0,07631471 ! Notch receptor processing GO:0007220 8 5 0,000 0,01271912 0,07612487 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01271912 0,07593598 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01271912 0,07574802 ! micturition GO:0060073 9 5 0,000 0,01271912 0,07556098 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01271912 0,07537487 ! copulation GO:0007620 9 5 0,000 0,01271912 0,07518968 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01271912 0,07500539 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01271912 0,074822 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01271912 0,07463951 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01271912 0,0744579 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01271912 0,07427718 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01271912 0,07409733 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01271912 0,07391835 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01271912 0,07374024 ! grooming behavior GO:0007625 6 5 0,000 0,01271912 0,07356298 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01271912 0,07338657 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01271912 0,073211 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01271912 0,07303627 ! response to protozoan GO:0001562 10 5 0,000 0,01271912 0,07286238 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01271912 0,07268931 ! lymph vessel development GO:0001945 10 5 0,000 0,01271912 0,07251706 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01271912 0,07234562 ! endochondral ossification GO:0001958 16 5 0,000 0,01271912 0,072175 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01271912 0,07200517 ! parathyroid gland development GO:0060017 13 5 0,000 0,01271912 0,07183615 ! anagen GO:0042640 6 5 0,000 0,01271912 0,07166791 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01271912 0,07150046 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01271912 0,0713338 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01271912 0,0711679 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01271912 0,07100278 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01271912 0,07083842 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01271912 0,07067482 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01271912 0,07051198 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01271912 0,07034988 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01271912 0,07018853 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01271912 0,07002791 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01271912 0,06986803 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01271912 0,06970888 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01271912 0,06955045 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01271912 0,06939274 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01271912 0,06923574 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01271912 0,06907945 ! histidine catabolic process GO:0006548 6 5 0,000 0,01271912 0,06892387 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01271912 0,06876898 ! microvillus organization GO:0032528 7 5 0,000 0,01271912 0,06861479 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01271912 0,06846129 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01271912 0,06830848 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01271912 0,06815634 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01271912 0,06800488 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01271912 0,0678541 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01271912 0,06770398 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01271912 0,06755452 ! polyol catabolic process GO:0046174 7 5 0,000 0,01271912 0,06740572 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01271912 0,06725758 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01271912 0,06711008 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01271912 0,06696323 ! muscle cell migration GO:0014812 8 5 0,000 0,01271912 0,06681703 ! mitochondrial fission GO:0000266 8 5 0,000 0,01271912 0,06667146 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01271912 0,06652652 ! mRNA transcription GO:0009299 9 5 0,000 0,01271912 0,06638221 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01271912 0,06623852 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01271912 0,06609546 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01271912 0,06595301 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01271912 0,06581118 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01271912 0,06566995 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01271912 0,06552933 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01271912 0,06538931 ! response to food GO:0032094 6 5 0,000 0,01271912 0,06524989 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01271912 0,06511106 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01271912 0,06497282 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01271912 0,06483517 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01271912 0,06469809 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01271912 0,0645616 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01271912 0,06442568 ! forebrain neuron development GO:0021884 13 5 0,000 0,01271912 0,06429033 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01271912 0,06415555 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01271912 0,06402134 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01271912 0,06388768 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01271912 0,06375458 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01271912 0,06362203 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01271912 0,06349004 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01271912 0,06335859 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01271912 0,06322768 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01271912 0,06309732 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01271912 0,06296749 ! basic amino acid transport GO:0015802 11 5 0,000 0,01271912 0,06283819 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01271912 0,06270942 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01271912 0,06258118 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01271912 0,06245347 ! depyrimidination GO:0045008 10 5 0,000 0,01271912 0,06232627 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01271912 0,06219959 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01271912 0,06207342 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01271912 0,06194777 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01271912 0,06182262 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01271912 0,06169798 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01271912 0,06157384 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01271912 0,0614502 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01271912 0,06132705 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01271912 0,0612044 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01271912 0,06108223 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01271912 0,06096055 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01271912 0,06083936 ! response to arsenic GO:0046685 10 5 0,000 0,01271912 0,06071865 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01271912 0,06059841 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01271912 0,06047865 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01271912 0,06035937 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01271912 0,06024055 ! response to cadmium ion GO:0046686 7 5 0,000 0,01271912 0,0601222 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01271912 0,06000431 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01271912 0,05988688 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01271912 0,05976992 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01271912 0,05965341 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01271912 0,05953735 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01271912 0,05942174 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01271912 0,05930659 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01271912 0,05919187 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01271912 0,0590776 ! neural tube patterning GO:0021532 7 5 0,000 0,01271912 0,05896377 ! embryonic cleavage GO:0040016 6 5 0,000 0,01271912 0,05885038 ! peroxisome fission GO:0016559 5 5 0,000 0,01271912 0,05873742 ! histone demethylation GO:0016577 10 5 0,000 0,01271912 0,0586249 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01271912 0,05851281 ! mitotic recombination GO:0006312 9 5 0,000 0,01271912 0,05840114 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01271912 0,0582899 ! metaphase plate congression GO:0051310 7 5 0,000 0,01271912 0,05817908 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01271912 0,05806869 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01271912 0,05795871 ! enteric nervous system development GO:0048484 8 5 0,000 0,01271912 0,05784915 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01271912 0,05774 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01271912 0,05763126 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01271912 0,05752293 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01271912 0,05741501 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01271912 0,05730749 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01271912 0,05720037 ! plasminogen activation GO:0031639 5 5 0,000 0,01271912 0,05709365 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01271912 0,05698733 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01271912 0,05688141 ! metaphase GO:0051323 8 5 0,000 0,01271912 0,05677588 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01271912 0,05667074 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01271912 0,05656599 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01271912 0,05646162 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01271912 0,05635764 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01271912 0,05625404 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01271912 0,05615082 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01271912 0,05604798 ! response to redox state GO:0051775 5 5 0,000 0,01271912 0,05594552 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01271912 0,05584343 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01271912 0,05574171 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01271912 0,05564036 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01271912 0,05553938 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01271912 0,05543876 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01271912 0,05533851 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01271912 0,05523862 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01271912 0,0551391 ! striatum development GO:0021756 9 5 0,000 0,01271912 0,05503992 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01271912 0,05494111 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01271912 0,05484265 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01271912 0,05474454 ! glial cell migration GO:0008347 11 5 0,000 0,01271912 0,05464678 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01271912 0,05454937 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01271912 0,05445231 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01271912 0,05435559 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01271912 0,05425922 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01271912 0,05416318 ! neuroprotection GO:0043526 6 5 0,000 0,01271912 0,05406749 ! neural plate development GO:0001840 8 5 0,000 0,01271912 0,05397213 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01271912 0,05387711 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01271912 0,05378242 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01271912 0,05368807 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01271912 0,05359404 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01271912 0,05350035 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01271912 0,05340698 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01271912 0,05331393 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01271912 0,05322121 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01271912 0,05312882 ! spindle assembly GO:0051225 6 5 0,000 0,01271912 0,05303674 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01271912 0,05294498 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01271912 0,05285354 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01271912 0,05276241 ! drug metabolic process GO:0017144 6 5 0,000 0,01271912 0,0526716 ! stem cell division GO:0017145 11 5 0,000 0,01271912 0,0525811 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01271912 0,05249091 ! organ regeneration GO:0031100 7 5 0,000 0,01271912 0,05240102 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01271912 0,05231145 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01271912 0,05222218 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01271912 0,05213322 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01281309 0,05242909 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,01281309 0,05234008 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01355088 0,05526004 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01355088 0,05516654 ! urogenital system development GO:0001655 137 69 1,000 0,01355088 0,05507335 ! reproductive structure development GO:0048608 113 71 1,000 0,01430674 0,05804726 ! humoral immune response GO:0006959 109 71 1,000 0,01430674 0,05794953 ! B cell activation GO:0042113 160 71 1,000 0,01430674 0,05785214 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01469139 0,05930785 ! carbohydrate transport GO:0008643 110 72 1,000 0,01469139 0,05920851 ! learning or memory GO:0007611 147 73 1,000 0,01508048 0,06067497 ! fertilization GO:0009566 90 73 1,000 0,01508048 0,06057367 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01524371 0,06112729 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01524371 0,06102558 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01524371 0,06092421 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01524371 0,06082318 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01524371 0,06072248 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01524371 0,06062211 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01524371 0,06052207 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01524371 0,06042237 ! sleep GO:0030431 13 6 0,000 0,01524371 0,06032299 ! response to oxygen radical GO:0000305 11 6 0,000 0,01524371 0,06022393 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01524371 0,06012521 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01524371 0,0600268 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01524371 0,05992872 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01524371 0,05983096 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01524371 0,05973351 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01524371 0,05963638 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01524371 0,05953957 ! forebrain regionalization GO:0021871 8 6 0,000 0,01524371 0,05944307 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01524371 0,05934689 ! male meiosis GO:0007140 7 6 0,000 0,01524371 0,05925101 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01524371 0,05915544 ! response to zinc ion GO:0010043 9 6 0,000 0,01524371 0,05906019 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01524371 0,05896523 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01524371 0,05887059 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01524371 0,05877624 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01524371 0,0586822 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01524371 0,05858846 ! malate metabolic process GO:0006108 11 6 0,000 0,01524371 0,05849502 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01524371 0,05840187 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01524371 0,05830902 ! protein refolding GO:0042026 15 6 0,000 0,01524371 0,05821647 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01524371 0,05812421 ! opsonization GO:0008228 8 6 0,000 0,01524371 0,05803224 ! mating behavior GO:0007617 7 6 0,000 0,01524371 0,05794056 ! neuron remodeling GO:0016322 15 6 0,000 0,01524371 0,05784917 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01524371 0,05775807 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01524371 0,05766726 ! equilibrioception GO:0050957 14 6 0,000 0,01524371 0,05757673 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01524371 0,05748648 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01524371 0,05739652 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01524371 0,05730684 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01524371 0,05721743 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01524371 0,05712831 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01524371 0,05703946 ! toxin metabolic process GO:0009404 11 6 0,000 0,01524371 0,05695089 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01524371 0,0568626 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01524371 0,05677458 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01524371 0,05668682 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01524371 0,05659935 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01524371 0,05651213 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01524371 0,05642519 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01524371 0,05633852 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01524371 0,05625211 ! protein lipoylation GO:0009249 10 6 0,000 0,01524371 0,05616597 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01524371 0,05608009 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01524371 0,05599447 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01524371 0,05590911 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01524371 0,05582401 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01524371 0,05573917 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01524371 0,05565459 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01524371 0,05557027 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01524371 0,0554862 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01524371 0,05540238 ! hyperosmotic response GO:0006972 9 6 0,000 0,01524371 0,05531882 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01524371 0,05523551 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01524371 0,05515244 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01524371 0,05506963 ! urea metabolic process GO:0019627 7 6 0,000 0,01524371 0,05498707 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01524371 0,05490475 ! neutrophil activation GO:0042119 8 6 0,000 0,01524371 0,05482268 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01524371 0,05474086 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01524371 0,05465928 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01524371 0,05457794 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01524371 0,05449684 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01524371 0,05441599 ! nucleoside salvage GO:0043174 9 6 0,000 0,01524371 0,05433537 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01524371 0,05425499 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01524371 0,05417485 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01524371 0,05409495 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01524371 0,05401528 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01524371 0,05393585 ! carnitine transport GO:0015879 10 6 0,000 0,01524371 0,05385665 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01524371 0,05377768 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01524371 0,05369894 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01524371 0,05362043 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01524371 0,05354215 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01524371 0,0534641 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01524371 0,05338628 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01524371 0,05330869 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01524371 0,05323131 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01524371 0,05315417 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01524371 0,05307724 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01524371 0,05300054 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01524371 0,05292406 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01524371 0,0528478 ! response to UV-C GO:0010225 11 6 0,000 0,01524371 0,05277176 ! astrocyte development GO:0014002 15 6 0,000 0,01524371 0,05269594 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01524371 0,05262034 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01524371 0,05254495 ! interaction with symbiont GO:0051702 13 6 0,000 0,01524371 0,05246978 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01524371 0,05239482 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01524371 0,05232008 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01524371 0,05224555 ! response to copper ion GO:0046688 10 6 0,000 0,01524371 0,05217123 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01524371 0,05209712 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01524371 0,05202323 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01524371 0,05194954 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01524371 0,05187606 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01524371 0,05180279 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01524371 0,05172973 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01524371 0,05165687 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01524371 0,05158421 ! hair follicle maturation GO:0048820 7 6 0,000 0,01524371 0,05151176 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01524371 0,05143952 ! Schwann cell development GO:0014044 15 6 0,000 0,01524371 0,05136747 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01524371 0,05129563 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01524371 0,05122399 ! subpallium development GO:0021544 10 6 0,000 0,01524371 0,05115255 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01524371 0,0510813 ! histone ubiquitination GO:0016574 8 6 0,000 0,01524371 0,05101026 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01524371 0,05093941 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01524371 0,05086876 ! G2 phase GO:0051319 16 6 0,000 0,01524371 0,0507983 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01524371 0,05072804 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01524371 0,05065798 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01524371 0,0505881 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01524371 0,05051842 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01524371 0,05044893 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01524371 0,05037964 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01524371 0,05031053 ! receptor internalization GO:0031623 10 6 0,000 0,01524371 0,05024161 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01524371 0,05017288 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01524371 0,05010434 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01524371 0,05003598 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01524371 0,04996781 ! protein deubiquitination GO:0016579 14 6 0,000 0,01524371 0,04989983 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01524371 0,04983203 ! protein destabilization GO:0031648 9 6 0,000 0,01524371 0,04976442 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01524371 0,04969699 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01524371 0,04962974 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01524371 0,04956267 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01524371 0,04949578 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01524371 0,04942908 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01524371 0,04936255 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01524371 0,0492962 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01524371 0,04923003 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01524371 0,04916404 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01524371 0,04909823 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01524371 0,04903259 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01524371 0,04896712 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01524371 0,04890183 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01524371 0,04883672 ! catecholamine transport GO:0051937 9 6 0,000 0,01524371 0,04877178 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01524371 0,04870701 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01524371 0,04864241 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01524371 0,04857798 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01524371 0,04851372 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01524371 0,04844964 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01524371 0,04838572 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01524371 0,04832197 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01524371 0,04825839 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01524371 0,04819497 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01524371 0,04813173 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01524371 0,04806864 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01547399 0,04873091 ! eye development GO:0001654 143 74 1,000 0,01547399 0,04866721 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01587189 0,04985348 ! rhythmic process GO:0048511 128 75 1,000 0,01587189 0,04978849 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,01627416 0,0509839 ! blood coagulation GO:0007596 146 78 1,000 0,01709173 0,05347554 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01709173 0,05340609 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01709173 0,05333682 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01750696 0,05456186 ! tRNA transcription GO:0009304 14 7 0,000 0,01776194 0,05528489 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01776194 0,05521346 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01776194 0,05514222 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01776194 0,05507116 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01776194 0,05500029 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01776194 0,05492959 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01776194 0,05485908 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01776194 0,05478875 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01776194 0,05471859 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01776194 0,05464862 ! prostate gland development GO:0030850 13 7 0,000 0,01776194 0,05457883 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01776194 0,05450921 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01776194 0,05443977 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01776194 0,05437051 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01776194 0,05430143 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01776194 0,05423252 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01776194 0,05416378 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01776194 0,05409522 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01776194 0,05402683 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01776194 0,05395861 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01776194 0,05389057 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01776194 0,0538227 ! glycolipid transport GO:0046836 10 7 0,000 0,01776194 0,053755 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01776194 0,05368746 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01776194 0,0536201 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01776194 0,05355291 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01776194 0,05348588 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01776194 0,05341903 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01776194 0,05335234 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01776194 0,05328581 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01776194 0,05321945 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01776194 0,05315326 ! mRNA stabilization GO:0048255 18 7 0,000 0,01776194 0,05308723 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01776194 0,05302137 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01776194 0,05295567 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01776194 0,05289013 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01776194 0,05282475 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01776194 0,05275953 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01776194 0,05269448 ! lipoprotein transport GO:0042953 14 7 0,000 0,01776194 0,05262958 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01776194 0,05256485 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01776194 0,05250027 ! rhythmic behavior GO:0007622 15 7 0,000 0,01776194 0,05243586 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01776194 0,0523716 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01776194 0,05230749 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01776194 0,05224355 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01776194 0,05217976 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01776194 0,05211612 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01776194 0,05205265 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01776194 0,05198932 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01776194 0,05192615 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01776194 0,05186313 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01776194 0,05180027 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01776194 0,05173756 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01776194 0,051675 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01776194 0,05161259 ! spinal cord patterning GO:0021511 13 7 0,000 0,01776194 0,05155033 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01776194 0,05148822 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01776194 0,05142626 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01776194 0,05136445 ! adrenal gland development GO:0030325 17 7 0,000 0,01776194 0,05130279 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01776194 0,05124127 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01776194 0,05117991 ! ovulation GO:0030728 9 7 0,000 0,01776194 0,05111869 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01776194 0,05105761 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01776194 0,05099668 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01776194 0,0509359 ! microtubule nucleation GO:0007020 20 7 0,000 0,01776194 0,05087526 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01776194 0,05081477 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01776194 0,05075442 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01776194 0,05069421 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01776194 0,05063415 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01776194 0,05057423 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01776194 0,05051445 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01776194 0,05045481 ! galactose metabolic process GO:0006012 13 7 0,000 0,01776194 0,05039531 ! vesicle fusion GO:0006906 17 7 0,000 0,01776194 0,05033595 ! response to dietary excess GO:0002021 8 7 0,000 0,01776194 0,05027673 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01776194 0,05021765 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01776194 0,05015871 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01776194 0,05009991 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01776194 0,05004124 ! purine salvage GO:0043101 10 7 0,000 0,01776194 0,04998272 ! nucleoside transport GO:0015858 8 7 0,000 0,01776194 0,04992432 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01776194 0,04986607 ! parturition GO:0007567 14 7 0,000 0,01776194 0,04980795 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01776194 0,04974997 ! rRNA modification GO:0000154 14 7 0,000 0,01776194 0,04969212 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01776194 0,0496344 ! spindle checkpoint GO:0031577 15 7 0,000 0,01776194 0,04957682 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01776194 0,04951938 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01776194 0,04946206 ! macrophage differentiation GO:0030225 11 7 0,000 0,01776194 0,04940488 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01776194 0,04934783 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01776194 0,04929091 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01776194 0,04923413 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01776194 0,04917747 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01776194 0,04912094 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01776194 0,04906455 ! fibrinolysis GO:0042730 10 7 0,000 0,01776194 0,04900828 ! eating behavior GO:0042755 7 7 0,000 0,01776194 0,04895214 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01776194 0,04889613 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01776194 0,04884025 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01776194 0,0487845 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01776194 0,04872887 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01776194 0,04867337 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01776194 0,048618 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01776194 0,04856275 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01776194 0,04850763 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01776194 0,04845263 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01776194 0,04839776 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01776194 0,04834301 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01776194 0,04828839 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01776194 0,04823388 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01776194 0,04817951 ! regulation of meiosis GO:0040020 12 7 0,000 0,01776194 0,04812525 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01776194 0,04807112 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01776194 0,0480171 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01776194 0,04796321 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01776194 0,04790944 ! transcription termination GO:0006353 13 7 0,000 0,01776194 0,04785579 ! response to tumor cell GO:0002347 13 7 0,000 0,01776194 0,04780226 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01776194 0,04774885 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01776194 0,04769556 ! anaphase GO:0051322 17 7 0,000 0,01776194 0,04764239 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01776194 0,04758933 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01776194 0,0475364 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01776194 0,04748358 ! diuresis GO:0030146 12 7 0,000 0,01776194 0,04743088 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01776194 0,04737829 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01776194 0,04732583 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01776194 0,04727348 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01776194 0,04722124 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01776194 0,04716912 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01776194 0,04711711 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01776194 0,04706522 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01776194 0,04701345 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01776194 0,04696178 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01776194 0,04691023 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01776194 0,0468588 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01776194 0,04680747 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,01776194 0,04675626 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01776194 0,04670516 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01776194 0,04665417 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01776194 0,0466033 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01776194 0,04655253 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01776194 0,04650187 ! adult feeding behavior GO:0008343 9 7 0,000 0,01776194 0,04645133 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01776194 0,04640089 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01776194 0,04635057 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01776194 0,04630035 ! muscle adaptation GO:0043500 14 7 0,000 0,01776194 0,04625024 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01776194 0,04620024 ! retina homeostasis GO:0001895 12 7 0,000 0,01776194 0,04615035 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01776194 0,04610056 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01776194 0,04605089 ! protein prenylation GO:0018342 18 7 0,000 0,01776194 0,04600132 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01776194 0,04595185 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01776194 0,04590249 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01776194 0,04585324 ! response to nutrient GO:0007584 125 82 1,000 0,01877823 0,04842488 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01877823 0,04837303 ! hemostasis GO:0007599 158 84 1,000 0,01964678 0,05055632 ! negative regulation of growth GO:0045926 155 84 1,000 0,01964678 0,05050231 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02027381 0,05205846 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02027381 0,05200296 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02027381 0,05194758 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02027381 0,05189231 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02027381 0,05183717 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02027381 0,05178214 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02027381 0,05172723 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02027381 0,05167243 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02027381 0,05161775 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02027381 0,05156319 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02027381 0,05150874 ! meiotic prophase I GO:0007128 13 8 0,000 0,02027381 0,0514544 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02027381 0,05140018 ! oligopeptide transport GO:0006857 15 8 0,000 0,02027381 0,05134608 ! UTP metabolic process GO:0046051 8 8 0,000 0,02027381 0,05129209 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02027381 0,05123821 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02027381 0,05118444 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02027381 0,05113079 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02027381 0,05107725 ! succinate metabolic process GO:0006105 14 8 0,000 0,02027381 0,05102382 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02027381 0,05097051 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02027381 0,0509173 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02027381 0,05086421 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02027381 0,05081122 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02027381 0,05075835 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02027381 0,05070559 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02027381 0,05065293 ! reflex GO:0060004 16 8 0,000 0,02027381 0,05060039 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02027381 0,05054795 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02027381 0,05049563 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02027381 0,05044341 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02027381 0,0503913 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02027381 0,05033929 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02027381 0,0502874 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02027381 0,05023561 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02027381 0,05018392 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02027381 0,05013235 ! histidine metabolic process GO:0006547 16 8 0,000 0,02027381 0,05008088 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02027381 0,05002951 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02027381 0,04997825 ! glycine catabolic process GO:0006546 13 8 0,000 0,02027381 0,0499271 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02027381 0,04987605 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02027381 0,0498251 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02027381 0,04977426 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02027381 0,04972352 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02027381 0,04967289 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02027381 0,04962236 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02027381 0,04957193 ! macrophage activation GO:0042116 12 8 0,000 0,02027381 0,0495216 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02027381 0,04947137 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02027381 0,04942125 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02027381 0,04937123 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02027381 0,04932131 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02027381 0,04927149 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02027381 0,04922177 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02027381 0,04917215 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02027381 0,04912263 ! osteoblast development GO:0002076 16 8 0,000 0,02027381 0,04907321 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02027381 0,04902389 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02027381 0,04897467 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02027381 0,04892555 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02027381 0,04887653 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02027381 0,0488276 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02027381 0,04877878 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02027381 0,04873005 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02027381 0,04868141 ! intermediate filament organization GO:0045109 12 8 0,000 0,02027381 0,04863288 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02027381 0,04858444 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02027381 0,04853609 ! cellular extravasation GO:0045123 12 8 0,000 0,02027381 0,04848785 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02027381 0,0484397 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02027381 0,04839164 ! response to antibiotic GO:0046677 11 8 0,000 0,02027381 0,04834368 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02027381 0,04829582 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02027381 0,04824805 ! DNA topological change GO:0006265 12 8 0,000 0,02027381 0,04820037 ! response to tropane GO:0014073 15 8 0,000 0,02027381 0,04815279 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02027381 0,0481053 ! melanosome transport GO:0032402 13 8 0,000 0,02027381 0,04805791 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02027381 0,04801061 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02027381 0,0479634 ! mast cell activation GO:0045576 14 8 0,000 0,02027381 0,04791628 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02027381 0,04786926 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02027381 0,04782233 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02027381 0,04777549 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02027381 0,04772874 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02027381 0,04768209 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02027381 0,04763552 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02027381 0,04758905 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02027381 0,04754267 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02027381 0,04749637 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02027381 0,04745017 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02027381 0,04740406 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02027381 0,04735803 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02027381 0,0473121 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02027381 0,04726625 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02027381 0,0472205 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02027381 0,04717483 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02027381 0,04712925 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02027381 0,04708376 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02027381 0,04703836 ! hormone catabolic process GO:0042447 17 8 0,000 0,02027381 0,04699304 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02027381 0,04694781 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02027381 0,04690267 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02027381 0,04685761 ! ATP catabolic process GO:0006200 11 8 0,000 0,02027381 0,04681264 ! blastocyst growth GO:0001832 19 8 0,000 0,02027381 0,04676776 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02027381 0,04672296 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02027381 0,04667825 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02027381 0,04663363 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02027381 0,04658909 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02027381 0,04654463 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02027381 0,04650026 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02027381 0,04645598 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02027381 0,04641177 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02027381 0,04636766 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02027381 0,04632362 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02027381 0,04627967 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02027381 0,04623581 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02027381 0,04619202 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02027381 0,04614832 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02027381 0,0461047 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02027381 0,04606117 ! tube morphogenesis GO:0035239 176 86 1,000 0,02053196 0,04660367 ! regulation of protein transport GO:0051223 154 87 1,000 0,02098072 0,04757739 GO:0070201|regulation of establishment of protein localization, ! cellular defense response GO:0006968 114 89 1,000 0,02189047 0,04959367 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02189047 0,04954701 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,02235142 0,05054277 ! sex differentiation GO:0007548 145 90 1,000 0,02235142 0,05049531 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02277933 0,05141376 ! axon extension GO:0048675 15 9 0,000 0,02277933 0,05136558 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02277933 0,05131748 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02277933 0,05126948 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02277933 0,05122156 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02277933 0,05117374 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02277933 0,051126 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02277933 0,05107835 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02277933 0,05103079 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02277933 0,05098332 ! phosphate transport GO:0006817 19 9 0,000 0,02277933 0,05093594 ! reproductive behavior GO:0019098 19 9 0,000 0,02277933 0,05088865 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02277933 0,05084144 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02277933 0,05079432 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02277933 0,05074729 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02277933 0,05070035 ! GTP metabolic process GO:0046039 9 9 0,000 0,02277933 0,05065349 ! RNA methylation GO:0001510 15 9 0,000 0,02277933 0,05060672 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02277933 0,05056003 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02277933 0,05051343 ! artery development GO:0060840 24 9 0,000 0,02277933 0,05046692 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02277933 0,05042049 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02277933 0,05037415 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02277933 0,05032789 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02277933 0,05028172 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02277933 0,05023563 ! chemosensory behavior GO:0007635 20 9 0,000 0,02277933 0,05018963 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02277933 0,05014371 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02277933 0,05009787 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02277933 0,05005212 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02277933 0,05000645 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02277933 0,04996087 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02277933 0,04991537 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02277933 0,04986995 ! protein targeting to ER GO:0045047 22 9 0,000 0,02277933 0,04982461 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02277933 0,04977936 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02277933 0,04973419 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02277933 0,0496891 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02277933 0,04964409 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02277933 0,04959916 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02277933 0,04955432 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02277933 0,04950955 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02277933 0,04946487 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02277933 0,04942026 ! mannose metabolic process GO:0006013 13 9 0,000 0,02277933 0,04937574 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02277933 0,0493313 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02277933 0,04928694 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02277933 0,04924265 ! receptor clustering GO:0043113 18 9 0,000 0,02277933 0,04919845 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02277933 0,04915433 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02277933 0,04911028 ! ruffle organization GO:0031529 15 9 0,000 0,02277933 0,04906631 ! retinol metabolic process GO:0042572 18 9 0,000 0,02277933 0,04902243 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02277933 0,04897862 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02277933 0,04893489 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02277933 0,04889123 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02277933 0,04884766 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,02277933 0,04880416 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02277933 0,04876074 ! segment specification GO:0007379 13 9 0,000 0,02277933 0,0487174 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02277933 0,04867413 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02277933 0,04863094 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02277933 0,04858783 ! response to amine stimulus GO:0014075 13 9 0,000 0,02277933 0,04854479 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02277933 0,04850183 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02277933 0,04845895 ! erythrocyte development GO:0048821 15 9 0,000 0,02277933 0,04841614 ! gas homeostasis GO:0033483 16 9 0,000 0,02277933 0,04837341 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02277933 0,04833075 ! renal water homeostasis GO:0003091 14 9 0,000 0,02277933 0,04828817 ! postreplication repair GO:0006301 22 9 0,000 0,02277933 0,04824566 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02277933 0,04820323 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02277933 0,04816087 ! icosanoid secretion GO:0032309 15 9 0,000 0,02277933 0,04811859 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02277933 0,04807638 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02277933 0,04803424 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02277933 0,04799218 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02277933 0,0479502 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02277933 0,04790828 ! sterol catabolic process GO:0016127 11 9 0,000 0,02277933 0,04786644 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02277933 0,04782467 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02277933 0,04778298 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02277933 0,04774135 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02277933 0,0476998 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02277933 0,04765832 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02277933 0,04761692 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02277933 0,04757558 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02277933 0,04753432 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02277933 0,04749313 ! purine base metabolic process GO:0006144 21 9 0,000 0,02277933 0,04745201 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02277933 0,04741096 ! pigment granule transport GO:0051904 17 9 0,000 0,02277933 0,04736999 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02277933 0,04732908 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02277933 0,04728824 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02277933 0,04724748 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02277933 0,04720678 ! mitochondrion localization GO:0051646 15 9 0,000 0,02277933 0,04716616 ! response to protein stimulus GO:0051789 149 91 1,000 0,02281638 0,04720224 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,02375825 0,04910854 ! transcription initiation GO:0006352 153 94 1,000 0,02423511 0,05005123 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02423511 0,05000831 ! detection of stimulus GO:0051606 151 96 1,000 0,02520059 0,05195598 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02527853 0,05207205 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02527853 0,05202751 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02527853 0,05198304 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02527853 0,05193865 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02527853 0,05189433 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02527853 0,05185009 ! synapsis GO:0007129 13 10 0,000 0,02527853 0,05180592 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02527853 0,05176183 ! N-glycan processing GO:0006491 20 10 0,000 0,02527853 0,05171782 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02527853 0,05167388 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02527853 0,05163001 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02527853 0,05158622 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02527853 0,0515425 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02527853 0,05149886 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02527853 0,05145529 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02527853 0,0514118 ! androgen metabolic process GO:0008209 17 10 0,000 0,02527853 0,05136837 ! phospholipid efflux GO:0033700 16 10 0,000 0,02527853 0,05132503 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02527853 0,05128175 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02527853 0,05123855 ! lung alveolus development GO:0048286 26 10 0,000 0,02527853 0,05119542 ! pathogenesis GO:0009405 13 10 0,000 0,02527853 0,05115236 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02527853 0,05110937 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02527853 0,05106646 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02527853 0,05102362 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02527853 0,05098085 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02527853 0,05093815 ! endoderm development GO:0007492 16 10 0,000 0,02527853 0,05089553 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02527853 0,05085297 ! arginine catabolic process GO:0006527 13 10 0,000 0,02527853 0,05081049 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02527853 0,05076808 ! proline metabolic process GO:0006560 13 10 0,000 0,02527853 0,05072573 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02527853 0,05068346 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02527853 0,05064126 ! V(D)J recombination GO:0033151 28 10 0,000 0,02527853 0,05059913 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02527853 0,05055707 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02527853 0,05051508 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02527853 0,05047316 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02527853 0,05043131 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02527853 0,05038952 ! multicellular organism growth GO:0035264 18 10 0,000 0,02527853 0,05034781 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02527853 0,05030617 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02527853 0,05026459 ! epithelial cell development GO:0002064 20 10 0,000 0,02527853 0,05022308 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02527853 0,05018165 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02527853 0,05014028 ! macroautophagy GO:0016236 17 10 0,000 0,02527853 0,05009897 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02527853 0,05005774 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02527853 0,05001657 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02527853 0,04997548 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02527853 0,04993445 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02527853 0,04989348 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02527853 0,04985259 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02527853 0,04981176 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02527853 0,04977099 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02527853 0,0497303 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02527853 0,04968967 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02527853 0,04964911 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02527853 0,04960861 ! response to dsRNA GO:0043331 20 10 0,000 0,02527853 0,04956818 ! DNA ligation GO:0006266 19 10 0,000 0,02527853 0,04952781 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02527853 0,04948751 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02527853 0,04944728 ! melanosome localization GO:0032400 16 10 0,000 0,02527853 0,04940711 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02527853 0,04936701 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02527853 0,04932697 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02527853 0,049287 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02527853 0,04924709 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02527853 0,04920725 ! mRNA cleavage GO:0006379 17 10 0,000 0,02527853 0,04916747 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02527853 0,04912775 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02527853 0,0490881 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02527853 0,04904851 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02527853 0,04900899 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02527853 0,04896953 ! salivary gland development GO:0007431 27 10 0,000 0,02527853 0,04893013 ! prophase GO:0051324 15 10 0,000 0,02527853 0,0488908 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02527853 0,04885153 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02527853 0,04881232 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02527853 0,04877318 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02527853 0,0487341 ! midbrain development GO:0030901 13 10 0,000 0,02527853 0,04869508 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02527853 0,04865612 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02527853 0,04861723 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02527853 0,0485784 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02527853 0,04853963 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02527853 0,04850092 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02527853 0,04846227 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02527853 0,04842369 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02527853 0,04838517 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02527853 0,0483467 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02527853 0,0483083 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02527853 0,04826996 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02527853 0,04823169 ! activation of innate immune response GO:0002218 12 10 0,000 0,02527853 0,04819347 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02527853 0,04815531 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02527853 0,04811721 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02527853 0,04807917 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02527853 0,0480412 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02527853 0,04800328 ! localization within membrane GO:0051668 20 10 0,000 0,02527853 0,04796542 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02667785 0,0505807 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,02717792 0,05148825 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02777143 0,05257125 ! respiratory burst GO:0045730 17 11 0,000 0,02777143 0,05252992 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02777143 0,05248865 ! neuron fate specification GO:0048665 17 11 0,000 0,02777143 0,05244745 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02777143 0,05240632 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02777143 0,05236525 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02777143 0,05232424 ! thyroid gland development GO:0030878 26 11 0,000 0,02777143 0,0522833 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02777143 0,05224242 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02777143 0,05220161 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02777143 0,05216086 ! response to pain GO:0048265 24 11 0,000 0,02777143 0,05212017 ! T cell proliferation GO:0042098 26 11 0,000 0,02777143 0,05207955 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02777143 0,05203899 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02777143 0,05199849 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02777143 0,05195805 ! bone resorption GO:0045453 16 11 0,000 0,02777143 0,05191768 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02777143 0,05187737 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02777143 0,05183713 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02777143 0,05179694 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02777143 0,05175682 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02777143 0,05171676 ! syncytium formation GO:0006949 18 11 0,000 0,02777143 0,05167677 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02777143 0,05163683 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02777143 0,05159696 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02777143 0,05155714 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02777143 0,05151739 ! lipid digestion GO:0044241 18 11 0,000 0,02777143 0,0514777 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02777143 0,05143807 ! UV protection GO:0009650 19 11 0,000 0,02777143 0,05139851 ! adult heart development GO:0007512 14 11 0,000 0,02777143 0,051359 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02777143 0,05131955 ! temperature homeostasis GO:0001659 17 11 0,000 0,02777143 0,05128017 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02777143 0,05124084 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02777143 0,05120158 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02777143 0,05116237 ! regulation of organ growth GO:0046620 13 11 0,000 0,02777143 0,05112323 ! pigment granule localization GO:0051875 20 11 0,000 0,02777143 0,05108414 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02777143 0,05104512 ! vasoconstriction GO:0042310 18 11 0,000 0,02777143 0,05100615 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02777143 0,05096724 ! embryonic axis specification GO:0000578 18 11 0,000 0,02777143 0,0509284 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02777143 0,05088961 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02777143 0,05085088 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02777143 0,05081221 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02777143 0,0507736 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02777143 0,05073505 ! zymogen activation GO:0031638 15 11 0,000 0,02777143 0,05069655 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02777143 0,05065812 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02777143 0,05061974 ! nucleosome positioning GO:0016584 15 11 0,000 0,02777143 0,05058142 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02777143 0,05054316 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02777143 0,05050496 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02777143 0,05046681 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02777143 0,05042872 ! acid secretion GO:0046717 18 11 0,000 0,02777143 0,05039069 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02777143 0,05035272 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02777143 0,0503148 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02777143 0,05027694 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02777143 0,05023914 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02777143 0,0502014 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,02777143 0,05016371 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02777143 0,05012607 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02777143 0,0500885 ! germ cell migration GO:0008354 25 11 0,000 0,02777143 0,05005098 ! embryonic gut development GO:0048566 15 11 0,000 0,02777143 0,05001352 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02777143 0,04997611 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02777143 0,04993876 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02777143 0,04990146 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02777143 0,04986422 ! defense response to fungus GO:0050832 13 11 0,000 0,02777143 0,04982704 ! developmental induction GO:0031128 19 11 0,000 0,02777143 0,04978991 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02777143 0,04975283 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02777143 0,04971582 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02777143 0,04967885 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02777143 0,04964194 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02777143 0,04960509 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02777143 0,04956829 ! nucleus localization GO:0051647 19 11 0,000 0,02777143 0,04953155 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02777143 0,04949486 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03025803 0,05388662 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03025803 0,05384676 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03025803 0,05380696 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03025803 0,05376722 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03025803 0,05372754 ! virus-host interaction GO:0019048 29 12 0,000 0,03025803 0,05368792 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03025803 0,05364836 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03025803 0,05360885 ! cartilage condensation GO:0001502 20 12 0,000 0,03025803 0,0535694 ! mating GO:0007618 17 12 0,000 0,03025803 0,05353001 ! protein complex disassembly GO:0043241 27 12 0,000 0,03025803 0,05349068 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03025803 0,05345141 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03025803 0,05341219 ! hippocampus development GO:0021766 26 12 0,000 0,03025803 0,05337303 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03025803 0,05333393 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03025803 0,05329489 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03025803 0,0532559 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03025803 0,05321697 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03025803 0,0531781 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03025803 0,05313928 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03025803 0,05310052 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03025803 0,05306182 ! drug transport GO:0015893 16 12 0,000 0,03025803 0,05302317 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03025803 0,05298458 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03025803 0,05294605 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03025803 0,05290757 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03025803 0,05286915 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03025803 0,05283078 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03025803 0,05279247 ! forebrain cell migration GO:0021885 21 12 0,000 0,03025803 0,05275422 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03025803 0,05271602 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03025803 0,05267787 ! entry into host cell GO:0030260 32 12 0,000 0,03025803 0,05263978 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,03025803 0,05260175 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03025803 0,05256377 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03025803 0,05252584 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03025803 0,05248797 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03025803 0,05245016 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03025803 0,0524124 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03025803 0,05237469 ! protein homotetramerization GO:0051289 21 12 0,000 0,03025803 0,05233704 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03025803 0,05229944 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03025803 0,05226189 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03025803 0,0522244 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03025803 0,05218697 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03025803 0,05214958 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03025803 0,05211225 ! cranial nerve development GO:0021545 20 12 0,000 0,03025803 0,05207498 ! fucose catabolic process GO:0019317 22 12 0,000 0,03025803 0,05203775 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03025803 0,05200058 ! histone acetylation GO:0016573 26 12 0,000 0,03025803 0,05196347 ! histone methylation GO:0016571 26 12 0,000 0,03025803 0,0519264 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03025803 0,05188939 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03025803 0,05185243 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03025803 0,05181553 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03025803 0,05177868 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03025803 0,05174188 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03025803 0,05170513 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03025803 0,05166843 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03025803 0,05163179 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03025803 0,05159519 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03025803 0,05155865 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03025803 0,05152216 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03025803 0,05148573 ! response to cold GO:0009409 17 12 0,000 0,03025803 0,05144934 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03025803 0,05141301 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03025803 0,05137672 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03273835 0,055549 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03273835 0,05550985 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03273835 0,05547076 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03273835 0,05543172 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03273835 0,05539274 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03273835 0,05535381 ! lipid localization GO:0010876 28 13 0,000 0,03273835 0,05531494 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03273835 0,05527612 ! organelle fusion GO:0048284 32 13 0,000 0,03273835 0,05523736 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03273835 0,05519865 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03273835 0,05516 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03273835 0,0551214 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03273835 0,05508285 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03273835 0,05504436 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03273835 0,05500592 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03273835 0,05496753 ! methionine metabolic process GO:0006555 27 13 0,000 0,03273835 0,0549292 ! plasma membrane organization GO:0007009 24 13 0,000 0,03273835 0,05489092 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03273835 0,0548527 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03273835 0,05481453 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03273835 0,05477641 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03273835 0,05473834 ! response to X-ray GO:0010165 25 13 0,000 0,03273835 0,05470033 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03273835 0,05466237 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03273835 0,05462446 ! exocrine system development GO:0035272 32 13 0,000 0,03273835 0,05458661 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,03273835 0,05454881 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03273835 0,05451106 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03273835 0,05447336 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03273835 0,05443571 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03273835 0,05439812 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03273835 0,05436058 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03273835 0,05432309 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03273835 0,05428565 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03273835 0,05424826 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03273835 0,05421093 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03273835 0,05417364 ! ribosome assembly GO:0042255 17 13 0,000 0,03273835 0,05413641 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,03273835 0,05409923 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03273835 0,0540621 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03273835 0,05402502 ! chromatin silencing GO:0006342 26 13 0,000 0,03273835 0,05398799 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03273835 0,05395101 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03273835 0,05391408 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03273835 0,05387721 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03273835 0,05384038 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03273835 0,0538036 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03273835 0,05376688 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03273835 0,0537302 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03273835 0,05369358 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03273835 0,053657 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03273835 0,05362047 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03273835 0,053584 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03273835 0,05354757 ! insulin secretion GO:0030073 23 13 0,000 0,03273835 0,05351119 ! actin filament polymerization GO:0030041 24 13 0,000 0,03273835 0,05347487 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03273835 0,05343859 ! acrosome reaction GO:0007340 18 13 0,000 0,03273835 0,05340236 ! rRNA transcription GO:0009303 25 14 0,000 0,03521241 0,0573991 ! lactation GO:0007595 26 14 0,000 0,03521241 0,05736024 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03521241 0,05732143 ! reproductive cellular process GO:0048610 20 14 0,000 0,03521241 0,05728267 ! tRNA modification GO:0006400 20 14 0,000 0,03521241 0,05724396 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03521241 0,05720531 ! regulation of S phase GO:0033261 23 14 0,000 0,03521241 0,05716671 ! water transport GO:0006833 21 14 0,000 0,03521241 0,05712816 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03521241 0,05708967 ! non-recombinational repair GO:0000726 25 14 0,000 0,03521241 0,05705122 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03521241 0,05701283 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03521241 0,05697449 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03521241 0,0569362 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03521241 0,05689796 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03521241 0,05685978 ! palate development GO:0060021 31 14 0,000 0,03521241 0,05682164 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03521241 0,05678356 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03521241 0,05674552 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03521241 0,05670754 ! arginine metabolic process GO:0006525 17 14 0,000 0,03521241 0,05666961 ! regulation of heart rate GO:0002027 24 14 0,000 0,03521241 0,05663173 ! organic alcohol transport GO:0015850 29 14 0,000 0,03521241 0,0565939 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03521241 0,05655612 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03521241 0,05651839 ! embryo implantation GO:0007566 30 14 0,000 0,03521241 0,05648071 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03521241 0,05644308 ! L-amino acid transport GO:0015807 30 14 0,000 0,03521241 0,0564055 ! bone mineralization GO:0030282 17 14 0,000 0,03521241 0,05636798 ! stem cell development GO:0048864 43 14 0,000 0,03521241 0,0563305 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03521241 0,05629307 ! cerebellum development GO:0021549 21 14 0,000 0,03521241 0,05625569 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03521241 0,05621836 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03521241 0,05618108 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03521241 0,05614385 ! cofactor transport GO:0051181 26 14 0,000 0,03521241 0,05610667 ! NADP metabolic process GO:0006739 24 14 0,000 0,03521241 0,05606954 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03521241 0,05603245 ! intestinal absorption GO:0050892 25 14 0,000 0,03521241 0,05599542 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03521241 0,05595843 ! oxygen transport GO:0015671 21 14 0,000 0,03521241 0,0559215 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03521241 0,05588461 ! male genitalia development GO:0030539 24 14 0,000 0,03521241 0,05584777 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03521241 0,05581098 ! regulation of axon extension GO:0030516 37 14 0,000 0,03521241 0,05577424 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03521241 0,05573754 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03768023 0,05960462 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03768023 0,05956546 ! superoxide anion generation GO:0042554 20 15 0,000 0,03768023 0,05952635 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03768023 0,05948729 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03768023 0,05944828 ! copper ion transport GO:0006825 20 15 0,000 0,03768023 0,05940933 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03768023 0,05937042 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03768023 0,05933157 ! sulfate transport GO:0008272 23 15 0,000 0,03768023 0,05929276 ! response to cAMP GO:0051591 22 15 0,000 0,03768023 0,05925401 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03768023 0,0592153 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03768023 0,05917665 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03768023 0,05913805 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03768023 0,0590995 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03768023 0,059061 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03768023 0,05902255 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03768023 0,05898415 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03768023 0,05894579 ! pituitary gland development GO:0021983 29 15 0,000 0,03768023 0,05890749 ! vesicle coating GO:0006901 33 15 0,000 0,03768023 0,05886924 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03768023 0,05883104 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03768023 0,05879289 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03768023 0,05875478 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03768023 0,05871673 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03768023 0,05867873 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03768023 0,05864077 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03768023 0,05860286 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03768023 0,05856501 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03768023 0,0585272 ! histone deacetylation GO:0016575 20 15 0,000 0,03768023 0,05848944 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03768023 0,05845173 ! tissue regeneration GO:0042246 26 15 0,000 0,03768023 0,05841407 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03768023 0,05837645 ! water homeostasis GO:0030104 27 15 0,000 0,03768023 0,05833889 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03768023 0,05830137 ! muscle maintenance GO:0046716 26 15 0,000 0,03768023 0,0582639 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03768023 0,05822648 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03768023 0,05818911 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03768023 0,05815178 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03768023 0,05811451 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03768023 0,05807728 ! cell killing GO:0001906 29 15 0,000 0,03768023 0,0580401 ! detection of bacterium GO:0016045 18 15 0,000 0,03768023 0,05800296 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03768023 0,05796588 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03768023 0,05792884 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03768023 0,05789185 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03768023 0,0578549 ! peptide hormone processing GO:0016486 23 15 0,000 0,03768023 0,057818 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04014181 0,0615559 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04014181 0,06151669 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04014181 0,06147753 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04014181 0,06143843 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04014181 0,06139937 ! bone remodeling GO:0046849 27 16 0,000 0,04014181 0,06136036 ! filopodium assembly GO:0046847 32 16 0,000 0,04014181 0,0613214 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04014181 0,06128249 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04014181 0,06124363 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04014181 0,06120482 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04014181 0,06116606 ! startle response GO:0001964 28 16 0,000 0,04014181 0,06112734 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04014181 0,06108868 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04014181 0,06105007 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04014181 0,0610115 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04014181 0,06097298 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04014181 0,06093451 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04014181 0,06089609 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04014181 0,06085772 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04014181 0,0608194 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04014181 0,06078112 ! response to osmotic stress GO:0006970 25 16 0,000 0,04014181 0,0607429 ! lysosomal transport GO:0007041 26 16 0,000 0,04014181 0,06070472 ! fructose metabolic process GO:0006000 25 16 0,000 0,04014181 0,06066659 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04014181 0,0606285 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04014181 0,06059047 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04014181 0,06055248 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04014181 0,06051454 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04014181 0,06047665 ! axon cargo transport GO:0008088 43 16 0,000 0,04014181 0,0604388 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04014181 0,060401 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04014181 0,06036325 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04014181 0,06032555 ! DNA replication initiation GO:0006270 27 16 0,000 0,04014181 0,06028789 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04014181 0,06025028 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04014181 0,06021272 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04014181 0,06017521 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04014181 0,06013774 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04014181 0,06010031 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04014181 0,06006294 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04014181 0,06002561 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04014181 0,05998833 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04014181 0,05995109 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04014181 0,0599139 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04259718 0,06353926 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04259718 0,06349989 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04259718 0,06346057 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04259718 0,0634213 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04259718 0,06338208 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04259718 0,06334291 ! signal complex assembly GO:0007172 41 17 0,000 0,04259718 0,06330378 ! endothelial cell migration GO:0043542 28 17 0,000 0,04259718 0,06326471 ! inositol metabolic process GO:0006020 28 17 0,000 0,04259718 0,06322568 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04259718 0,0631867 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04259718 0,06314777 ! glial cell development GO:0021782 27 17 0,000 0,04259718 0,06310888 ! limbic system development GO:0021761 36 17 0,000 0,04259718 0,06307005 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04259718 0,06303126 ! adult walking behavior GO:0007628 33 17 0,000 0,04259718 0,06299252 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04259718 0,06295382 ! heart looping GO:0001947 30 17 0,000 0,04259718 0,06291518 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04259718 0,06287658 ! myoblast differentiation GO:0045445 45 17 0,000 0,04259718 0,06283803 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04259718 0,06279952 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04259718 0,06276107 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04259718 0,06272266 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04259718 0,0626843 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,04259718 0,06264598 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04259718 0,06260771 ! NAD metabolic process GO:0019674 29 17 0,000 0,04259718 0,06256949 ! membrane budding GO:0006900 37 17 0,000 0,04259718 0,06253131 ! DNA integration GO:0015074 29 17 0,000 0,04259718 0,06249319 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04259718 0,0624551 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04259718 0,06241707 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04259718 0,06237908 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04259718 0,06234113 ! genitalia development GO:0048806 30 17 0,000 0,04259718 0,06230324 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04259718 0,06226539 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04259718 0,06222758 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04259718 0,06218982 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04259718 0,06215211 ! steroid catabolic process GO:0006706 31 17 0,000 0,04259718 0,06211444 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04259718 0,06207682 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04259718 0,06203924 ! gas transport GO:0015669 25 17 0,000 0,04259718 0,06200171 ! organic cation transport GO:0015695 31 17 0,000 0,04259718 0,06196422 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04259718 0,06192678 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04259718 0,06188939 ! microspike assembly GO:0030035 36 17 0,000 0,04259718 0,06185204 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04259718 0,06181473 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04504635 0,06532943 ! neuron maturation GO:0042551 42 18 0,000 0,04504635 0,06529008 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04504635 0,06525077 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04504635 0,06521151 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04504635 0,0651723 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04504635 0,06513313 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04504635 0,06509401 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04504635 0,06505494 ! memory GO:0007613 31 18 0,000 0,04504635 0,06501591 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04504635 0,06497693 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04504635 0,064938 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04504635 0,06489912 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04504635 0,06486028 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04504635 0,06482149 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04504635 0,06478274 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04504635 0,06474404 ! response to retinoic acid GO:0032526 26 18 0,000 0,04504635 0,06470539 ! response to fungus GO:0009620 21 18 0,000 0,04504635 0,06466678 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04504635 0,06462822 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04504635 0,06458971 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04504635 0,06455124 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04504635 0,06451281 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04504635 0,06447444 ! vitamin transport GO:0051180 27 18 0,000 0,04504635 0,0644361 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04504635 0,06439782 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04504635 0,06435958 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04504635 0,06432138 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04504635 0,06428323 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,04504635 0,06424513 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04504635 0,06420707 ! nerve development GO:0021675 28 18 0,000 0,04504635 0,06416905 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04504635 0,06413108 ! protein secretion GO:0009306 39 19 0,000 0,04748934 0,0675691 ! positive regulation of translation GO:0045727 30 19 0,000 0,04748934 0,06752917 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04748934 0,06748928 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04748934 0,06744944 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04748934 0,06740965 ! skin development GO:0043588 36 19 0,000 0,04748934 0,0673699 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04748934 0,0673302 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04748934 0,06729055 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04748934 0,06725094 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04748934 0,06721138 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04748934 0,06717187 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04748934 0,0671324 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04748934 0,06709298 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04748934 0,06705361 ! cerebral cortex development GO:0021987 36 19 0,000 0,04748934 0,06701428 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04748934 0,066975 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04748934 0,06693576 ! heme metabolic process GO:0042168 36 19 0,000 0,04748934 0,06689658 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04748934 0,06685743 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04748934 0,06681833 ! peptide cross-linking GO:0018149 37 19 0,000 0,04748934 0,06677928 ! protein export from nucleus GO:0006611 36 19 0,000 0,04748934 0,06674027 ! heart process GO:0003015 30 19 0,000 0,04748934 0,06670131 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04748934 0,0666624 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04748934 0,06662353 ! visual learning GO:0008542 36 19 0,000 0,04748934 0,0665847 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04748934 0,06654592 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04748934 0,06650719 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04748934 0,0664685 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04748934 0,06642986 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04748934 0,06639126 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04748934 0,0663527 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04748934 0,06631419 ! cilium assembly GO:0042384 37 19 0,000 0,04748934 0,06627573 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04748934 0,0662373 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04992616 0,06959579 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04992616 0,06955549 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04992616 0,06951524 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04992616 0,06947503 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04992616 0,06943487 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04992616 0,06939476 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,04992616 0,0693547 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04992616 0,06931468 ! response to vitamin GO:0033273 31 20 0,000 0,04992616 0,0692747 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04992616 0,06923477 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04992616 0,06919489 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04992616 0,06915506 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04992616 0,06911527 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04992616 0,06907552 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04992616 0,06903582 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04992616 0,06899617 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04992616 0,06895656 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04992616 0,068917 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04992616 0,06887748 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,04992616 0,06883801 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04992616 0,06879859 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04992616 0,06875921 ! body fluid secretion GO:0007589 31 20 0,000 0,04992616 0,06871987 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04992616 0,06868058 ! peptide secretion GO:0002790 35 20 0,000 0,04992616 0,06864133 ! stem cell differentiation GO:0048863 53 20 0,000 0,04992616 0,06860213 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04992616 0,06856298 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04992616 0,06852386 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04992616 0,0684848 ! sensory perception of pain GO:0019233 30 20 0,000 0,04992616 0,06844577 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04992616 0,0684068 ! diencephalon development GO:0021536 34 20 0,000 0,04992616 0,06836786 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04992616 0,06832897 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04992616 0,06829013 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04992616 0,06825133 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04992616 0,06821257 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04992616 0,06817386 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04992616 0,06813519 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04992616 0,06809656 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04992616 0,06805798 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04992616 0,06801944 ! actin filament-based movement GO:0030048 43 20 0,000 0,04992616 0,06798095 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04992616 0,0679425 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04992616 0,06790409 ! negative regulation of translation GO:0017148 29 20 0,000 0,04992616 0,06786572 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04992616 0,0678274 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04992616 0,06778913 ! regulation of cell killing GO:0031341 42 21 0,000 0,05235682 0,07104936 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05235682 0,07100931 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05235682 0,0709693 ! hormone secretion GO:0046879 38 21 0,000 0,05235682 0,07092934 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05235682 0,07088943 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05235682 0,07084956 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05235682 0,07080973 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05235682 0,07076995 ! axis specification GO:0009798 38 21 0,000 0,05235682 0,07073021 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05235682 0,07069052 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05235682 0,07065087 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05235682 0,07061127 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05235682 0,07057171 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05235682 0,0705322 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05235682 0,07049273 ! cytolysis GO:0019835 24 21 0,000 0,05235682 0,07045331 ! vasodilation GO:0042311 39 21 0,000 0,05235682 0,07041392 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05235682 0,07037459 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05235682 0,07033529 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05235682 0,07029604 ! collagen fibril organization GO:0030199 59 21 0,000 0,05235682 0,07025684 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05235682 0,07021768 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05235682 0,07017856 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05235682 0,07013948 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05235682 0,07010045 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05235682 0,07006146 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05235682 0,07002252 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05235682 0,06998362 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05478135 0,07318374 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05478135 0,07314313 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05478135 0,07310256 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05478135 0,07306204 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05478135 0,07302156 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05478135 0,07298113 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05478135 0,07294074 ! keratinization GO:0031424 28 22 0,000 0,05478135 0,0729004 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05478135 0,0728601 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05478135 0,07281984 ! sensory perception of taste GO:0050909 28 22 0,000 0,05478135 0,07277963 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05478135 0,07273947 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05478135 0,07269935 ! vacuolar transport GO:0007034 36 22 0,000 0,05478135 0,07265927 ! lysosome organization GO:0007040 41 22 0,000 0,05478135 0,07261924 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05478135 0,07257925 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05478135 0,07253931 ! fucose metabolic process GO:0006004 39 22 0,000 0,05478135 0,07249941 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05478135 0,07245955 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05478135 0,07241974 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05478135 0,07237997 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,05478135 0,07234024 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05478135 0,07230056 ! sarcomere organization GO:0045214 30 22 0,000 0,05478135 0,07226092 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05478135 0,07222133 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05478135 0,07218177 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05478135 0,07214227 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05478135 0,0721028 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05478135 0,07206338 ! protein stabilization GO:0050821 39 22 0,000 0,05478135 0,072024 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,05719975 0,07516253 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05719975 0,0751215 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05719975 0,07508052 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05719975 0,07503958 ! gluconeogenesis GO:0006094 33 23 0,000 0,05719975 0,07499869 ! viral genome replication GO:0019079 41 23 0,000 0,05719975 0,07495784 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05719975 0,07491704 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05719975 0,07487628 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05719975 0,07483556 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05719975 0,07479489 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05719975 0,07475426 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05719975 0,07471368 ! visual behavior GO:0007632 42 23 0,000 0,05719975 0,07467314 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05719975 0,07463264 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05719975 0,07459219 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,05719975 0,07455179 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05719975 0,07451142 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05719975 0,0744711 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05719975 0,07443083 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05719975 0,07439059 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05719975 0,0743504 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05719975 0,07431026 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05719975 0,07427015 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05719975 0,07423009 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05719975 0,07419008 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05719975 0,07415011 ! fatty acid transport GO:0015908 44 23 0,000 0,05719975 0,07411018 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05719975 0,07407029 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05719975 0,07403044 ! hormone transport GO:0009914 40 23 0,000 0,05719975 0,07399064 ! cell-cell recognition GO:0009988 25 23 0,000 0,05719975 0,07395088 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05719975 0,07391117 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05719975 0,0738715 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05719975 0,07383186 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05719975 0,07379228 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05719975 0,07375273 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05961204 0,07682195 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05961204 0,07678082 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05961204 0,07673974 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05961204 0,07669871 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05961204 0,07665771 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05961204 0,07661676 ! vesicle docking GO:0048278 47 24 0,000 0,05961204 0,07657586 ! spinal cord development GO:0021510 47 24 0,000 0,05961204 0,07653499 ! vacuole organization GO:0007033 43 24 0,000 0,05961204 0,07649418 ! digestive system process GO:0022600 39 24 0,000 0,05961204 0,0764534 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05961204 0,07641267 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05961204 0,07637198 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05961204 0,07633134 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05961204 0,07629073 ! membrane depolarization GO:0051899 39 24 0,000 0,05961204 0,07625017 ! pallium development GO:0021543 49 24 0,000 0,05961204 0,07620966 ! pentose metabolic process GO:0019321 35 24 0,000 0,05961204 0,07616919 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,05961204 0,07612876 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05961204 0,07608837 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05961204 0,07604803 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05961204 0,07600773 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05961204 0,07596747 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05961204 0,07592725 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05961204 0,07588708 ! regulation of amine transport GO:0051952 40 24 0,000 0,05961204 0,07584695 ! protein tetramerization GO:0051262 52 24 0,000 0,05961204 0,07580686 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06201825 0,07882509 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06201825 0,07878348 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06201825 0,0787419 ! phototransduction GO:0007602 33 25 0,000 0,06201825 0,07870037 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06201825 0,07865888 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06201825 0,07861744 ! sperm motility GO:0030317 31 25 0,000 0,06201825 0,07857604 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06201825 0,07853469 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06201825 0,07849337 ! receptor metabolic process GO:0043112 46 25 0,000 0,06201825 0,0784521 ! chromosome condensation GO:0030261 45 25 0,000 0,06201825 0,07841088 ! response to starvation GO:0042594 42 25 0,000 0,06201825 0,0783697 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06201825 0,07832856 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,06201825 0,07828746 ! neural crest cell development GO:0014032 54 25 0,000 0,06201825 0,07824641 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06201825 0,0782054 ! negative regulation of cell development GO:0010721 73 25 0,000 0,06201825 0,07816443 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06201825 0,07812351 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06201825 0,07808263 ! interaction with host GO:0051701 62 25 0,000 0,06201825 0,07804179 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06201825 0,078001 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06201825 0,07796024 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06201825 0,07791953 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,06201825 0,07787886 ! immunoglobulin production GO:0002377 55 25 0,000 0,06201825 0,07783824 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06201825 0,07779766 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06201825 0,07775711 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06201825 0,07771662 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,06201825 0,07767616 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06201825 0,07763575 ! telomere organization GO:0032200 43 25 0,000 0,06201825 0,07759537 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06201825 0,07755504 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06201825 0,07751476 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06441837 0,0804728 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06441837 0,08043104 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06441837 0,08038932 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06441837 0,08034764 ! initiation of viral infection GO:0019059 57 26 0,000 0,06441837 0,08030601 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06441837 0,08026443 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06441837 0,08022288 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06441837 0,08018138 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06441837 0,08013992 ! tube lumen formation GO:0035148 50 26 0,000 0,06441837 0,0800985 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06441837 0,08005713 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,06441837 0,0800158 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06441837 0,07997451 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06441837 0,07993327 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06441837 0,07989207 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06441837 0,07985091 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06441837 0,07980979 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06441837 0,07976871 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06441837 0,07972768 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06441837 0,07968669 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06441837 0,07964574 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06441837 0,07960483 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06441837 0,07956397 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06441837 0,07952314 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06441837 0,07948236 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,06681244 0,08239402 ! neuron fate commitment GO:0048663 48 27 0,000 0,06681244 0,08235181 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06681244 0,08230964 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06681244 0,08226752 ! iron ion transport GO:0006826 59 27 0,000 0,06681244 0,08222543 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06681244 0,0821834 ! protein amino acid acylation GO:0043543 55 27 0,000 0,06681244 0,0821414 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06681244 0,08209945 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06681244 0,08205754 ! fat cell differentiation GO:0045444 50 27 0,000 0,06681244 0,08201568 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06681244 0,08197385 ! autophagy GO:0006914 41 27 0,000 0,06681244 0,08193207 ! primary neural tube formation GO:0014020 51 27 0,000 0,06681244 0,08189033 ! base-excision repair GO:0006284 41 27 0,000 0,06681244 0,08184864 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06681244 0,08180698 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06681244 0,08176537 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06681244 0,08172381 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06681244 0,08168228 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06681244 0,0816408 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06681244 0,08159935 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06920046 0,08447301 ! circadian rhythm GO:0007623 50 28 0,000 0,06920046 0,08443017 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06920046 0,08438738 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06920046 0,08434463 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,06920046 0,08430192 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06920046 0,08425926 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06920046 0,08421664 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06920046 0,08417406 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06920046 0,08413153 ! synaptogenesis GO:0007416 42 28 0,000 0,06920046 0,08408904 ! lipid oxidation GO:0034440 43 28 0,000 0,06920046 0,08404659 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06920046 0,08400419 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06920046 0,08396182 ! translational initiation GO:0006413 65 29 0,000 0,07158244 0,08680814 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07158244 0,08676441 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07158244 0,08672072 ! regulation of pH GO:0006885 43 29 0,000 0,07158244 0,08667708 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07158244 0,08663348 ! catechol metabolic process GO:0009712 54 29 0,000 0,07158244 0,08658992 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07158244 0,08654641 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07158244 0,08650294 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07158244 0,08645951 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07158244 0,08641613 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07158244 0,08637279 ! cell fate determination GO:0001709 60 29 0,000 0,07158244 0,0863295 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07158244 0,08628625 ! detection of light stimulus GO:0009583 38 29 0,000 0,07158244 0,08624304 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,07158244 0,08619988 ! regulation of coagulation GO:0050818 46 29 0,000 0,07158244 0,08615675 ! phenol metabolic process GO:0018958 55 30 0,000 0,07395841 0,08897197 ! zinc ion transport GO:0006829 45 30 0,000 0,07395841 0,0889275 ! membrane docking GO:0022406 61 30 0,000 0,07395841 0,08888308 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07395841 0,08883871 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07395841 0,08879438 ! acute-phase response GO:0006953 49 30 0,000 0,07395841 0,08875009 ! myofibril assembly GO:0030239 47 30 0,000 0,07395841 0,08870585 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07395841 0,08866165 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07395841 0,0886175 ! phospholipid transport GO:0015914 51 30 0,000 0,07395841 0,08857339 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07395841 0,08852932 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07395841 0,0884853 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07395841 0,08844132 ! eye morphogenesis GO:0048592 60 30 0,000 0,07395841 0,08839738 ! regulation of B cell activation GO:0050864 50 30 0,000 0,07395841 0,08835349 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07632838 0,09113949 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07632838 0,09109428 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07632838 0,09104912 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07632838 0,091004 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07632838 0,09095893 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07632838 0,0909139 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07632838 0,09086891 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07632838 0,09082397 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07632838 0,09077908 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07632838 0,09073423 ! peptide transport GO:0015833 55 31 0,000 0,07632838 0,09068942 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07632838 0,09064466 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07632838 0,09059994 ! mesoderm formation GO:0001707 69 31 0,000 0,07632838 0,09055526 ! natural killer cell activation GO:0030101 45 31 0,000 0,07632838 0,09051063 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07632838 0,09046605 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07632838 0,0904215 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,07632838 0,09037701 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07632838 0,09033255 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07869236 0,09308447 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07869236 0,09303873 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07869236 0,09299303 ! cholesterol transport GO:0030301 56 32 0,000 0,07869236 0,09294738 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07869236 0,09290177 ! spliceosome assembly GO:0000245 67 32 0,000 0,07869236 0,09285621 ! spindle organization GO:0007051 46 32 0,000 0,07869236 0,09281069 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07869236 0,09276522 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07869236 0,09271979 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07869236 0,09267441 ! muscle cell development GO:0055001 49 32 0,000 0,07869236 0,09262907 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07869236 0,09258377 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07869236 0,09253852 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07869236 0,09249331 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07869236 0,09244815 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07869236 0,09240303 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07869236 0,09235796 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,07869236 0,09231293 ! gene silencing GO:0016458 65 32 0,000 0,07869236 0,09226794 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,08105037 0,09498645 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08105037 0,0949402 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08105037 0,09489401 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08105037 0,09484785 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08105037 0,09480174 ! cell fate specification GO:0001708 52 33 0,000 0,08105037 0,09475568 ! sterol transport GO:0015918 57 33 0,000 0,08105037 0,09470966 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08105037 0,09466368 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08105037 0,09461775 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08105037 0,09457186 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08340242 0,09726913 ! glial cell differentiation GO:0010001 63 34 0,000 0,08340242 0,097222 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08340242 0,09717492 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08340242 0,09712789 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08340242 0,0970809 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08340242 0,09703395 ! mismatch repair GO:0006298 46 34 0,000 0,08340242 0,09698705 ! spermatid development GO:0007286 63 34 0,000 0,08340242 0,0969402 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08340242 0,09689339 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08340242 0,09684663 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,08340242 0,09679991 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,08574853 0,09947491 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08574853 0,09942697 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,08574853 0,09937907 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08574853 0,09933123 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08574853 0,09928342 ! odontogenesis GO:0042476 66 35 0,000 0,08574853 0,09923567 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08574853 0,09918796 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08574853 0,0991403 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08574853 0,09909268 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,08574853 0,09904511 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,08574853 0,09899758 ! cytokine production GO:0001816 59 35 0,000 0,08574853 0,0989501 ! neural tube formation GO:0001841 67 35 0,000 0,08574853 0,09890266 ! vesicle localization GO:0051648 64 35 0,000 0,08574853 0,09885527 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08808871 0,10150452 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,08808871 0,10145593 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08808871 0,10140739 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08808871 0,10135889 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08808871 0,10131044 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,08808871 0,10126203 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08808871 0,10121367 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08808871 0,10116536 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08808871 0,1011171 ! aerobic respiration GO:0009060 55 36 0,000 0,08808871 0,10106888 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,08808871 0,1010207 ! embryonic organ development GO:0048568 57 36 0,000 0,08808871 0,10097257 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08808871 0,10092449 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09042298 0,10354959 ! meiosis I GO:0007127 65 37 0,000 0,09042298 0,10350033 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09042298 0,10345111 ! sister chromatid segregation GO:0000819 58 37 0,000 0,09042298 0,10340194 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09042298 0,10335282 ! organic anion transport GO:0015711 68 37 0,000 0,09042298 0,10330375 ! tissue remodeling GO:0048771 76 37 0,000 0,09042298 0,10325472 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,09042298 0,10320573 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,09042298 0,1031568 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09042298 0,10310791 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09042298 0,10305907 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09042298 0,10301027 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,09042298 0,10296152 ! spermatid differentiation GO:0048515 66 37 0,000 0,09042298 0,10291281 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09275135 0,10551288 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,09275135 0,10546302 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09275135 0,1054132 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,09275135 0,10536343 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,09275135 0,10531371 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,09275135 0,10526403 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,09275135 0,1052144 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,09275135 0,10516482 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,09275135 0,10511529 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09275135 0,1050658 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09275135 0,10501635 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,09275135 0,10496696 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,09275135 0,10491761 ! glucan metabolic process GO:0044042 62 38 0,000 0,09275135 0,1048683 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09507384 0,10744371 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09507384 0,10739327 ! segmentation GO:0035282 67 39 0,000 0,09507384 0,10734287 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09507384 0,10729252 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09507384 0,10724222 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09507384 0,10719197 ! RNA modification GO:0009451 57 39 0,000 0,09507384 0,10714176 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09507384 0,1070916 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09739046 0,10964972 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09739046 0,10959843 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09739046 0,10954719 ! feeding behavior GO:0007631 59 40 0,000 0,09739046 0,109496 ! negative regulation of binding GO:0051100 72 40 0,000 0,09739046 0,10944486 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09739046 0,10939377 ! maintenance of protein location GO:0045185 91 40 0,000 0,09739046 0,10934272 ! cytokinesis GO:0000910 72 40 0,000 0,09739046 0,10929172 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09970123 0,11183271 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,09970123 0,11178059 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09970123 0,11172853 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09970123 0,11167651 ! gliogenesis GO:0042063 88 41 0,000 0,09970123 0,11162455 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,09970123 0,11157263 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09970123 0,11152076 ! polyol metabolic process GO:0019751 66 41 0,000 0,09970123 0,11146894 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,09970123 0,11141716 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,10200616 0,11394002 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 0,000 0,10200616 0,11388715 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10200616 0,11383433 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,10200616 0,11378155 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,10200616 0,11372883 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,10200616 0,11367615 ! regulation of protein secretion GO:0050708 71 42 0,000 0,10200616 0,11362352 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10430526 0,1161307 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10430526 0,11607699 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10430526 0,11602332 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10430526 0,11596971 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10430526 0,11591614 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10430526 0,11586263 ! neural tube development GO:0021915 77 43 0,000 0,10430526 0,11580916 ! striated muscle contraction GO:0006941 77 43 0,000 0,10430526 0,11575574 ! phagocytosis GO:0006909 90 43 0,000 0,10430526 0,11570238 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10430526 0,11564906 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10659855 0,11813732 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10659855 0,11808293 ! double-strand break repair GO:0006302 81 44 0,000 0,10659855 0,11802858 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10659855 0,11797429 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10659855 0,11792005 ! maintenance of location in cell GO:0051651 97 44 0,000 0,10659855 0,11786586 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,10888605 0,12033984 ! glycolysis GO:0006096 65 45 0,000 0,10888605 0,12028459 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,10888605 0,12022939 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,10888605 0,12017424 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,10888605 0,12011914 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,10888605 0,12006409 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,10888605 0,12000909 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,10888605 0,11995414 ! cell growth GO:0016049 84 45 0,000 0,10888605 0,11989924 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11116777 0,12235574 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,11116777 0,12229979 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11116777 0,1222439 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,11116777 0,12218805 ! endosome transport GO:0016197 108 47 0,000 0,11344371 0,12463268 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,11344371 0,1245758 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,11344371 0,12451897 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,11344371 0,12446219 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,11344371 0,12440546 ! protein homooligomerization GO:0051260 76 47 0,000 0,11344371 0,12434878 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,11571391 0,12677945 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11571391 0,12672174 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11571391 0,12666409 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11571391 0,12660649 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11571391 0,12654894 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11571391 0,12649145 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11797837 0,12890825 ! regulation of ion transport GO:0043269 77 49 0,000 0,11797837 0,12884973 ! peptide metabolic process GO:0006518 76 49 0,000 0,11797837 0,12879127 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11797837 0,12873286 ! endocrine system development GO:0035270 104 49 0,000 0,11797837 0,12867451 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11797837 0,1286162 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11797837 0,12855795 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11797837 0,12849976 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,12023711 0,13090067 ! neuromuscular process GO:0050905 99 50 0,000 0,12023711 0,13084147 ! inner ear development GO:0048839 79 50 0,000 0,12023711 0,13078231 ! histone modification GO:0016570 91 50 0,000 0,12023711 0,13072322 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12023711 0,13066417 ! viral infectious cycle GO:0019058 99 51 0,000 0,12249013 0,13305249 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12249013 0,13299245 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12249013 0,13293246 ! excretion GO:0007588 83 51 0,000 0,12249013 0,13287253 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12249013 0,13281265 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12249013 0,13275282 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,12249013 0,13269305 ! covalent chromatin modification GO:0016569 101 52 0,000 0,12473746 0,13506676 ! amino acid activation GO:0043038 92 52 0,000 0,12473746 0,135006 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,12697912 0,13737039 ! RNA catabolic process GO:0006401 93 53 0,000 0,12697912 0,13730865 ! regulation of translational initiation GO:0006446 82 53 0,000 0,12697912 0,13724697 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,12697912 0,13718534 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,12697912 0,13712377 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,12697912 0,13706225 ! cell maturation GO:0048469 100 53 0,000 0,12697912 0,13700079 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,12697912 0,13693938 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,1292151 0,13928832 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1292151 0,13922594 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1292151 0,13916362 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,1292151 0,13910135 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1292151 0,13903914 ! chloride transport GO:0006821 90 55 0,000 0,13144543 0,14137582 ! glucose catabolic process GO:0006007 82 55 0,000 0,13144543 0,14131265 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13144543 0,14124953 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13144543 0,14118647 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,13144543 0,14112347 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,13144543 0,14106053 ! gastrulation GO:0007369 112 55 0,000 0,13144543 0,14099764 ! heart morphogenesis GO:0003007 97 55 0,000 0,13144543 0,14093481 ! RNA elongation GO:0006354 79 55 0,000 0,13144543 0,14087203 ! nuclear export GO:0051168 97 55 0,000 0,13144543 0,14080931 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13367012 0,14312876 ! sensory perception of smell GO:0007608 80 56 0,000 0,13367012 0,14306509 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13367012 0,14300147 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,13367012 0,14293792 ! proton transport GO:0015992 94 56 0,000 0,13367012 0,14287442 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13367012 0,14281097 ! lipid modification GO:0030258 97 57 0,000 0,13588919 0,14511735 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,13588919 0,14505297 ! maintenance of location GO:0051235 118 57 0,000 0,13588919 0,14498864 ! hydrogen transport GO:0006818 97 58 0,000 0,13810265 0,147285 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13810265 0,14721975 ! adult behavior GO:0030534 99 58 0,000 0,13810265 0,14715455 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,13810265 0,14708941 ! positive regulation of secretion GO:0051047 95 59 0,000 0,14031051 0,14937482 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14031051 0,14930875 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14031051 0,14924274 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,14031051 0,14917679 ! establishment of organelle localization GO:0051656 109 59 0,000 0,14031051 0,1491109 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,14251279 0,15138444 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,14251279 0,15131764 ! camera-type eye development GO:0043010 116 60 0,000 0,14251279 0,15125089 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1447095 0,15351457 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,1447095 0,15344691 ! mesoderm development GO:0007498 119 61 0,000 0,1447095 0,15337932 ! tRNA processing GO:0008033 89 61 0,000 0,1447095 0,15331178 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1447095 0,1532443 ! viral reproductive process GO:0022415 126 62 0,000 0,14690065 0,15549625 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14690065 0,15542787 ! regulation of mitosis GO:0007088 105 63 0,000 0,14908627 0,15767101 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,14908627 0,15760174 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,14908627 0,15753252 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,14908627 0,15746337 ! cell redox homeostasis GO:0045454 102 64 0,000 0,15126636 0,15969585 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,15126636 0,15962581 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,15344093 0,16184957 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,15344093 0,16177865 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,15344093 0,16170779 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,15344093 0,16163699 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,15561 0,16385018 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15561 0,16377851 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15561 0,1637069 ! developmental maturation GO:0021700 116 66 0,000 0,15561 0,16363535 ! cell projection assembly GO:0030031 120 66 0,000 0,15561 0,16356386 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15777359 0,16576562 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15777359 0,16569326 ! activation of MAPK activity GO:0000187 115 67 0,000 0,15777359 0,16562097 ! lung development GO:0030324 144 67 0,000 0,15777359 0,16554874 ! chromosome segregation GO:0007059 113 67 0,000 0,15777359 0,16547658 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15777359 0,16540447 ! hexose catabolic process GO:0019320 104 67 0,000 0,15777359 0,16533243 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15777359 0,16526046 ! adaptive immune response GO:0002250 119 67 0,000 0,15777359 0,16518854 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,15777359 0,16511669 ! amino acid transport GO:0006865 125 68 0,000 0,15993171 0,16730248 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,15993171 0,16722977 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,15993171 0,16715712 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,15993171 0,16708454 ! viral reproduction GO:0016032 134 68 0,000 0,15993171 0,16701202 ! regulation of lipase activity GO:0060191 130 68 0,000 0,15993171 0,16693957 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,15993171 0,16686717 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,15993171 0,16679484 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,16208437 0,16896664 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16208437 0,16889346 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16208437 0,16882035 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,16208437 0,16874729 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16208437 0,16867431 ! appendage morphogenesis GO:0035107 135 70 0,000 0,16423159 0,17083493 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,16423159 0,1707611 ! amine catabolic process GO:0009310 117 71 0,000 0,16637337 0,17291332 ! appendage development GO:0048736 136 71 0,000 0,16637337 0,17283866 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16637337 0,17276406 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16637337 0,17268953 ! acute inflammatory response GO:0002526 113 72 0,000 0,16850974 0,17483158 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,16850974 0,17475622 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,16850974 0,17468092 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,16850974 0,17460569 ! respiratory system development GO:0060541 153 72 0,000 0,16850974 0,17453053 ! regulation of blood pressure GO:0008217 125 73 0,000 0,1706407 0,17666158 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,1706407 0,1765856 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,17276627 0,17870836 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,17276627 0,17863156 ! neurotransmitter transport GO:0006836 123 74 0,000 0,17276627 0,17855483 ! meiosis GO:0007126 121 74 0,000 0,17276627 0,17847816 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,17276627 0,17840156 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,17276627 0,17832503 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,17276627 0,17824856 ! organelle localization GO:0051640 136 74 0,000 0,17276627 0,17817216 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,17488646 0,18028142 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,17488646 0,18020421 ! meiotic cell cycle GO:0051321 122 75 0,000 0,17488646 0,18012707 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17700129 0,18222726 ! defense response to bacterium GO:0042742 89 76 0,000 0,17700129 0,18214932 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,17700129 0,18207145 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,17700129 0,18199364 ! regulation of catabolic process GO:0009894 161 76 0,000 0,17700129 0,1819159 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,17911077 0,18400535 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,17911077 0,18392681 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,17911077 0,18384835 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,17911077 0,18376995 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,18121492 0,18584957 ! protein oligomerization GO:0051259 139 78 0,000 0,18121492 0,18577038 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,18331374 0,18784193 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,18331374 0,18776196 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,18331374 0,18768206 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,18331374 0,18760223 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,18331374 0,18752247 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,18540725 0,18958344 ! muscle cell differentiation GO:0042692 159 80 0,000 0,18540725 0,1895029 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,18540725 0,18942244 ! protein import into nucleus GO:0006606 158 80 0,000 0,18540725 0,18934204 ! inorganic anion transport GO:0015698 138 80 0,000 0,18540725 0,1892617 ! digestion GO:0007586 112 81 0,000 0,18749546 0,19131216 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,18749546 0,19123106 ! nuclear import GO:0051170 161 81 0,000 0,18749546 0,19115003 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,18957839 0,1931917 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,18957839 0,19310991 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,18957839 0,19302819 ! regulation of lyase activity GO:0051339 160 83 0,000 0,19165605 0,1950611 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,19372845 0,19708695 ! regulation of ligase activity GO:0051340 142 84 0,000 0,19372845 0,19700365 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,19372845 0,19692042 ! response to unfolded protein GO:0006986 131 85 0,000 0,1957956 0,19893759 ! nucleosome assembly GO:0006334 122 85 0,000 0,1957956 0,19885362 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,1957956 0,19876971 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,19785753 0,20077824 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,19785753 0,2006936 ! chromatin assembly GO:0031497 124 86 0,000 0,19785753 0,20060902 ! alcohol catabolic process GO:0046164 130 86 0,000 0,19785753 0,20052452 ! amine transport GO:0015837 155 86 0,000 0,19785753 0,20044009 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,19991424 0,20243841 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,19991424 0,20235324 ! protein localization in nucleus GO:0034504 176 87 0,000 0,19991424 0,20226815 ! cellular respiration GO:0045333 135 88 0,000 0,20196574 0,20425791 ! regulation of neurological system process GO:0031644 148 88 0,000 0,20196574 0,20417209 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,20196574 0,20408634 ! ossification GO:0001503 188 90 0,000 0,20605318 0,20812928 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,20605318 0,20804194 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,20605318 0,20795468 ! bone development GO:0060348 189 91 0,000 0,20808914 0,20992137 ! sterol metabolic process GO:0016125 152 91 0,000 0,20808914 0,20983339 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,20808914 0,20974549 ! nucleosome organization GO:0034728 138 92 0,000 0,21011995 0,21170377 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21011995 0,21161516 ! vitamin metabolic process GO:0006766 139 92 0,000 0,21011995 0,21152661 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,21214562 0,21347653 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,21214562 0,21338728 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,21214562 0,21329811 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,21416617 0,21523968 ! forebrain development GO:0030900 188 95 0,000 0,2161816 0,2171745 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,2161816 0,21708386 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,21819192 0,21901117 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,21819192 0,21891984 ! positive regulation of immune response GO:0050778 156 96 0,000 0,21819192 0,21882858 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,22019716 0,22074765 ! protein ubiquitination GO:0016567 217 97 0,000 0,22019716 0,22065571 ! hormone metabolic process GO:0042445 157 97 0,000 0,22019716 0,22056385 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,22219732 0,22247472 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,22219732 0,22238218 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,22419242 0,22428564 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,22419242 0,22419242