pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6130-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,843E-06 3,397E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 5,293E-06 4,877E-03 ! protein oligomerization GO:0051259 39 39 3,000 7,226E-06 4,439E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 7,651E-06 3,525E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 8,569E-06 3,159E-03 GO:0033674|positive regulation of kinase activity, ! regulation of caspase activity GO:0043281 41 41 3,000 8,858E-06 2,721E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 9,134E-06 2,405E-03 ! protein tetramerization GO:0051262 13 13 2,000 9,134E-06 2,104E-03 ! regulation of endopeptidase activity GO:0052548 42 42 3,000 9,769E-06 2E-03 ! regulation of peptidase activity GO:0052547 46 46 3,000 1,412E-05 2,602E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,821E-05 3,05E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 1,975E-05 3,033E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 2,153E-05 3,052E-03 ! DNA damage checkpoint GO:0000077 19 19 2,000 3,055E-05 4,021E-03 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 3,055E-05 3,753E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 4,174E-05 4,808E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 5,964E-05 6,466E-03 ! glucose homeostasis GO:0042593 24 24 2,000 6,311E-05 6,462E-03 GO:0033500|carbohydrate homeostasis, ! regulation of gene-specific transcription GO:0032583 25 25 2,000 7,156E-05 6,941E-03 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 7,156E-05 6,594E-03 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 8,401E-05 7,373E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 9,061E-05 7,591E-03 ! activation of caspase activity GO:0006919 27 27 2,000 9,061E-05 7,26E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,063E-04 8,16E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,063E-04 7,834E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,063E-04 7,532E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,063E-04 7,253E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,063E-04 6,994E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,063E-04 6,753E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,127E-04 6,923E-03 ! response to UV GO:0009411 29 29 2,000 1,127E-04 6,7E-03 ! positive regulation of peptidase activity GO:0010952 30 30 2,000 1,249E-04 7,196E-03 GO:0043280|positive regulation of caspase activity, ! MAPKKK cascade GO:0000165 82 81 3,000 1,332E-04 7,438E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 1,38E-04 7,482E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,38E-04 7,268E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,591E-04 8,144E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 1,591E-04 7,923E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,591E-04 7,715E-03 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 1,591E-04 7,517E-03 ! ER overload response GO:0006983 6 6 1,000 1,591E-04 7,329E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,591E-04 7,15E-03 ! nitric oxide metabolic process GO:0046209 6 6 1,000 1,591E-04 6,98E-03 GO:0006809|nitric oxide biosynthetic process, ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,591E-04 6,818E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 1,591E-04 6,663E-03 ! localization within membrane GO:0051668 6 6 1,000 1,591E-04 6,515E-03 ! positive regulation of cell migration GO:0030335 36 36 2,000 2,169E-04 8,689E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,222E-04 8,715E-03 ! response to X-ray GO:0010165 7 7 1,000 2,222E-04 8,533E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,222E-04 8,359E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,222E-04 8,192E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 2,222E-04 8,031E-03 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 2,222E-04 7,877E-03 ! regulation of transcription factor activity GO:0051090 38 37 2,000 2,355E-04 8,189E-03 GO:0090046|regulation of transcription regulator activity, ! DNA damage response, signal transduction GO:0042770 37 37 2,000 2,355E-04 8,037E-03 ! activation of MAPK activity GO:0000187 39 39 2,000 2,758E-04 9,241E-03 ! positive regulation of cell motion GO:0051272 39 39 2,000 2,758E-04 9,076E-03 ! sex determination GO:0007530 8 8 1,000 2,957E-04 9,562E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 2,957E-04 9,397E-03 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 2,957E-04 9,238E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 2,957E-04 9,084E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 2,957E-04 8,935E-03 ! cell cycle checkpoint GO:0000075 42 41 2,000 3,203E-04 9,521E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 3,794E-04 0,01110024 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 3,794E-04 0,0109268 ! regulation of cellular pH GO:0030641 9 9 1,000 3,794E-04 0,0107587 ! histone acetylation GO:0016573 9 9 1,000 3,794E-04 0,01059569 ! regulation of DNA binding GO:0051101 47 45 2,000 4,226E-04 0,01162581 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 4,511E-04 0,01222733 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 4,733E-04 0,012643 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 4,733E-04 0,01246238 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 4,733E-04 0,01228685 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 4,733E-04 0,0121162 ! negative regulation of coagulation GO:0050819 11 10 1,000 4,733E-04 0,01195023 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 5,774E-04 0,01437917 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 5,774E-04 0,01418744 ! protein amino acid acetylation GO:0006473 11 11 1,000 5,774E-04 0,01400077 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 5,774E-04 0,01381894 GO:0032388|positive regulation of intracellular transport, ! activation of MAPKK activity GO:0000186 12 11 1,000 5,774E-04 0,01364177 ! cellular response to starvation GO:0009267 11 11 1,000 5,774E-04 0,01346909 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 5,774E-04 0,01330073 ! G1/S transition checkpoint GO:0031575 12 11 1,000 5,774E-04 0,01313652 ! interaction with host GO:0051701 11 11 1,000 5,774E-04 0,01297632 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 5,774E-04 0,01281998 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 5,774E-04 0,01266736 GO:0006109|regulation of carbohydrate metabolic process, ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 6,122E-04 0,01327395 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 2,000 6,483E-04 0,01389252 ! regulation of protein transport GO:0051223 53 53 2,000 6,857E-04 0,0145251 GO:0070201|regulation of establishment of protein localization, ! translational initiation GO:0006413 12 12 1,000 6,914E-04 0,01448039 ! xenobiotic metabolic process GO:0006805 12 12 1,000 6,914E-04 0,01431769 ! regulation of insulin secretion GO:0050796 12 12 1,000 6,914E-04 0,0141586 ! somitogenesis GO:0001756 13 12 1,000 6,914E-04 0,01400301 ! G1 phase GO:0051318 13 12 1,000 6,914E-04 0,01385081 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 6,914E-04 0,01370187 ! positive regulation of DNA replication GO:0045740 14 13 1,000 8,155E-04 0,01598829 ! gluconeogenesis GO:0006094 13 13 1,000 8,155E-04 0,01582 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 8,155E-04 0,0156552 ! mitochondrial membrane organization GO:0007006 13 13 1,000 8,155E-04 0,01549381 ! negative regulation of DNA replication GO:0008156 13 13 1,000 8,155E-04 0,01533571 ! cell aging GO:0007569 13 13 1,000 8,155E-04 0,0151808 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 8,155E-04 0,015029 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 8,155E-04 0,01488019 ! regulation of peptide secretion GO:0002791 13 13 1,000 8,155E-04 0,01473431 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 8,155E-04 0,01459126 GO:0001952|regulation of cell-matrix adhesion, ! regulation of binding GO:0051098 60 57 2,000 8,49E-04 0,01504508 ! regulation of protein localization GO:0032880 58 57 2,000 8,49E-04 0,01490179 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 9,392E-04 0,01632894 ! pyruvate metabolic process GO:0006090 14 14 1,000 9,494E-04 0,01635346 ! protein amino acid acylation GO:0043543 14 14 1,000 9,494E-04 0,01620203 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 9,494E-04 0,01605339 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 9,494E-04 0,01590745 ! base-excision repair GO:0006284 14 14 1,000 9,494E-04 0,01576414 ! regulation of blood coagulation GO:0030193 15 14 1,000 9,494E-04 0,01562339 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,093E-03 0,01783115 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 1,093E-03 0,01767474 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,093E-03 0,01752105 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,093E-03 0,01737 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,093E-03 0,01722154 ! response to starvation GO:0042594 15 15 1,000 1,093E-03 0,0170756 ! response to ionizing radiation GO:0010212 16 15 1,000 1,093E-03 0,0169321 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 1,093E-03 0,016791 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 1,000 1,093E-03 0,01665223 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,247E-03 0,01883679 ! segmentation GO:0035282 17 16 1,000 1,247E-03 0,01868364 ! triglyceride metabolic process GO:0006641 16 16 1,000 1,247E-03 0,01853297 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,247E-03 0,0183847 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,247E-03 0,01823879 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 1,247E-03 0,01809518 ! regulation of coagulation GO:0050818 17 16 1,000 1,247E-03 0,01795381 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 1,36E-03 0,01943032 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,41E-03 0,01999392 ! response to toxin GO:0009636 18 17 1,000 1,41E-03 0,01984129 ! negative regulation of cell development GO:0010721 18 17 1,000 1,41E-03 0,01969098 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,41E-03 0,01954293 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 1,41E-03 0,01939708 ! response to radiation GO:0009314 70 68 2,000 1,42E-03 0,0193814 ! regulation of cell size GO:0008361 68 68 2,000 1,42E-03 0,01923889 ! positive regulation of transport GO:0051050 71 70 2,000 1,544E-03 0,0207699 ! growth GO:0040007 70 70 2,000 1,544E-03 0,02061939 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 1,583E-03 0,02099404 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 1,583E-03 0,02084408 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 1,583E-03 0,02069625 ! neutral lipid metabolic process GO:0006638 18 18 1,000 1,583E-03 0,0205505 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 1,000 1,583E-03 0,02040679 ! hexose biosynthetic process GO:0019319 18 18 1,000 1,583E-03 0,02026508 ! B cell differentiation GO:0030183 18 18 1,000 1,583E-03 0,02012532 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 1,583E-03 0,01998748 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 1,583E-03 0,01985151 ! regulation of cell migration GO:0030334 71 71 2,000 1,609E-03 0,02003072 ! regulation of pH GO:0006885 19 19 1,000 1,766E-03 0,02184472 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 1,766E-03 0,02169909 ! negative regulation of binding GO:0051100 21 20 1,000 1,958E-03 0,0239018 ! organic ether metabolic process GO:0018904 20 20 1,000 1,958E-03 0,02374455 GO:0006662|glycerol ether metabolic process, ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 1,958E-03 0,02358936 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 1,958E-03 0,02343618 ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 1,958E-03 0,02328498 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,16E-03 0,02551914 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,16E-03 0,0253566 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 2,16E-03 0,02519611 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,16E-03 0,02503765 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 2,16E-03 0,02488116 ! regulation of locomotion GO:0040012 79 79 2,000 2,187E-03 0,02503637 ! regulation of cell motion GO:0051270 79 79 2,000 2,187E-03 0,02488182 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 2,371E-03 0,02681102 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 2,371E-03 0,02664754 ! hormone-mediated signaling GO:0009755 22 22 1,000 2,371E-03 0,02648604 ! regulation of hormone secretion GO:0046883 23 23 1,000 2,592E-03 0,02877525 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 2,592E-03 0,02860294 ! positive regulation of growth GO:0045927 23 23 1,000 2,592E-03 0,02843269 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 2,592E-03 0,02826445 ! calcium-mediated signaling GO:0019722 23 23 1,000 2,592E-03 0,02809819 ! cell projection assembly GO:0030031 25 23 1,000 2,592E-03 0,02793387 ! regulation of cellular localization GO:0060341 86 85 2,000 2,696E-03 0,02889071 ! mitochondrial transport GO:0006839 24 24 1,000 2,822E-03 0,0300599 ! gliogenesis GO:0042063 24 24 1,000 2,822E-03 0,02988714 ! T cell differentiation GO:0030217 24 24 1,000 2,822E-03 0,02971636 ! heart development GO:0007507 90 87 2,000 2,881E-03 0,03016776 ! negative regulation of secretion GO:0051048 26 25 1,000 3,061E-03 0,03187062 ! alcohol biosynthetic process GO:0046165 25 25 1,000 3,061E-03 0,03169157 ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,061E-03 0,03151452 ! heart morphogenesis GO:0003007 25 25 1,000 3,061E-03 0,03133944 ! negative regulation of cell cycle GO:0045786 92 91 2,000 3,273E-03 0,03332979 ! positive regulation of binding GO:0051099 27 26 1,000 3,309E-03 0,03350986 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 3,309E-03 0,03332675 ! double-strand break repair GO:0006302 27 26 1,000 3,309E-03 0,03314562 ! response to insulin stimulus GO:0032868 28 26 1,000 3,309E-03 0,03296646 ! cell growth GO:0016049 27 27 1,000 3,567E-03 0,03534053 ! regulation of response to stress GO:0080134 97 94 2,000 3,588E-03 0,03536375 ! histone modification GO:0016570 28 28 1,000 3,833E-03 0,03757779 ! positive regulation of cell cycle GO:0045787 29 29 1,000 4,109E-03 0,04006638 ! viral reproductive process GO:0022415 29 29 1,000 4,109E-03 0,0398555 ! covalent chromatin modification GO:0016569 29 29 1,000 4,109E-03 0,03964683 ! positive regulation of protein transport GO:0051222 29 29 1,000 4,109E-03 0,03944034 ! response to hormone stimulus GO:0009725 102 100 2,000 4,272E-03 0,04079757 ! hemopoiesis GO:0030097 104 100 2,000 4,272E-03 0,04058727 ! activation of phospholipase C activity GO:0007202 30 30 1,000 4,393E-03 0,04152304 GO:0010863|positive regulation of phospholipase C activity, ! regulation of ossification GO:0030278 30 30 1,000 4,393E-03 0,04131119 ! B cell activation GO:0042113 31 31 1,000 4,687E-03 0,04384701 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 4,687E-03 0,04362556 ! aging GO:0007568 32 31 1,000 4,687E-03 0,04340634 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 4,687E-03 0,04318931 ! positive regulation of lipase activity GO:0060193 32 32 1,000 4,989E-03 0,0457465 ! negative regulation of cell growth GO:0030308 32 32 1,000 4,989E-03 0,04552003 ! regulation of phospholipase activity GO:0010517 32 32 1,000 4,989E-03 0,04529579 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 4,989E-03 0,04507375 ! negative regulation of cell size GO:0045792 33 33 1,000 5,3E-03 0,04765093 ! regulation of cellular response to stress GO:0080135 35 33 1,000 5,3E-03 0,04741961 ! activation of protein kinase activity GO:0032147 35 33 1,000 5,3E-03 0,04719053 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 5,3E-03 0,04696365 ! regulation of angiogenesis GO:0045765 35 34 1,000 5,62E-03 0,04955952 ! regulation of bone remodeling GO:0046850 34 34 1,000 5,62E-03 0,04932352 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 5,62E-03 0,04908976 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 5,62E-03 0,0488582 ! viral reproduction GO:0016032 34 34 1,000 5,62E-03 0,04862882 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 5,949E-03 0,05123102 ! multicellular organism reproduction GO:0032504 36 35 1,000 5,949E-03 0,05099274 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 1,000 5,949E-03 0,05075666 ! regulation of tissue remodeling GO:0034103 35 35 1,000 5,949E-03 0,05052276 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 6,286E-03 0,05314144 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 6,286E-03 0,05289879 ! regulation of lipase activity GO:0060191 36 36 1,000 6,286E-03 0,05265834 ! coagulation GO:0050817 39 36 1,000 6,286E-03 0,05242007 GO:0007596|blood coagulation, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 6,632E-03 0,05505416 ! response to drug GO:0042493 37 37 1,000 6,632E-03 0,05480728 ! lung development GO:0030324 38 37 1,000 6,632E-03 0,05456261 ! negative regulation of growth GO:0045926 37 37 1,000 6,632E-03 0,05432011 ! positive regulation of secretion GO:0051047 39 38 1,000 6,986E-03 0,0569686 ! negative regulation of kinase activity GO:0033673 38 38 1,000 6,986E-03 0,05671764 ! RNA elongation GO:0006354 38 38 1,000 6,986E-03 0,05646887 ! regulation of homeostatic process GO:0032844 38 38 1,000 6,986E-03 0,05622228 ! hemostasis GO:0007599 42 39 1,000 7,349E-03 0,05888422 ! respiratory tube development GO:0030323 40 39 1,000 7,349E-03 0,05862931 ! nucleotide-excision repair GO:0006289 40 39 1,000 7,349E-03 0,05837659 ! respiratory system development GO:0060541 40 39 1,000 7,349E-03 0,05812605 ! lymphocyte differentiation GO:0030098 39 39 1,000 7,349E-03 0,05787765 ! negative regulation of transferase activity GO:0051348 40 40 1,000 7,72E-03 0,06054179 ! mitochondrion organization GO:0007005 44 43 1,000 8,883E-03 0,06936895 ! protein import into nucleus GO:0006606 44 44 1,000 9,287E-03 0,07221921 ! homophilic cell adhesion GO:0007156 45 45 1,000 9,699E-03 0,07510847 ! nuclear import GO:0051170 45 45 1,000 9,699E-03 0,07479421 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,01011967 0,07771066 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01054807 0,08066425 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01098443 0,08365411 ! leukocyte differentiation GO:0002521 50 49 1,000 0,0114287 0,08667939 ! ossification GO:0001503 50 49 1,000 0,0114287 0,08632415 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 1,000 0,0114287 0,08597181 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,0114287 0,08562233 GO:0060538|skeletal muscle organ development, ! negative regulation of transport GO:0051051 51 50 1,000 0,01188083 0,08864931 ! T cell activation GO:0042110 51 50 1,000 0,01188083 0,08829185 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01188083 0,08793726 ! transcription initiation GO:0006352 50 50 1,000 0,01188083 0,08758551 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01188083 0,08723657 ! cell fate commitment GO:0045165 52 52 1,000 0,01280848 0,09367471 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,01280848 0,09330446 ! response to hypoxia GO:0001666 53 53 1,000 0,01328388 0,09638661 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,01328388 0,09600862 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,01376694 0,09911122 ! response to oxygen levels GO:0070482 55 54 1,000 0,01376694 0,09872557 ! hormone metabolic process GO:0042445 55 54 1,000 0,01376694 0,09834291 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01376694 0,09796321 ! in utero embryonic development GO:0001701 55 55 1,000 0,0142576 0,10106443 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,0142576 0,10067721 ! reproductive developmental process GO:0003006 56 56 1,000 0,0147558 0,10379749 ! regulation of nervous system development GO:0051960 57 56 1,000 0,0147558 0,10340282 ! dephosphorylation GO:0016311 60 59 1,000 0,0162952 0,11375775 ! regulation of cell development GO:0060284 60 59 1,000 0,0162952 0,11332848 ! protein localization in organelle GO:0033365 59 59 1,000 0,0162952 0,11290243 ! rRNA transcription GO:0009303 5 5 0,000 0,01660853 0,11464238 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01660853 0,11421461 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01660853 0,11379002 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01660853 0,11336858 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01660853 0,11295025 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01660853 0,11253499 ! reproductive cellular process GO:0048610 5 5 0,000 0,01660853 0,11212277 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01660853 0,11171356 ! prostate gland development GO:0030850 5 5 0,000 0,01660853 0,11130733 ! metencephalon development GO:0022037 5 5 0,000 0,01660853 0,11090405 ! water transport GO:0006833 5 5 0,000 0,01660853 0,11050367 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01660853 0,11010617 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01660853 0,10971153 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01660853 0,1093197 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01660853 0,10893066 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01660853 0,10854438 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01660853 0,10816084 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01660853 0,10777999 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01660853 0,10740181 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01660853 0,10702628 ! filopodium assembly GO:0046847 7 5 0,000 0,01660853 0,10665337 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01660853 0,10628304 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01660853 0,10591528 ! GTP metabolic process GO:0046039 5 5 0,000 0,01660853 0,10555006 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01660853 0,10518734 ! mRNA stabilization GO:0048255 5 5 0,000 0,01660853 0,10482711 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01660853 0,10446934 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01660853 0,104114 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01660853 0,10376107 ! social behavior GO:0035176 5 5 0,000 0,01660853 0,10341053 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01660853 0,10306235 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01660853 0,1027165 ! memory GO:0007613 5 5 0,000 0,01660853 0,10237297 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,01660853 0,10203172 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01660853 0,10169275 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01660853 0,10135602 ! response to lipid GO:0033993 5 5 0,000 0,01660853 0,10102151 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01660853 0,1006892 ! hippocampus development GO:0021766 6 5 0,000 0,01660853 0,10035907 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01660853 0,1000311 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01660853 0,09970527 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01660853 0,09938155 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01660853 0,09905992 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01660853 0,09874038 ! heart looping GO:0001947 5 5 0,000 0,01660853 0,09842288 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01660853 0,09810742 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01660853 0,09779398 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01660853 0,09748254 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01660853 0,09717307 ! pH reduction GO:0045851 5 5 0,000 0,01660853 0,09686556 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01660853 0,09655999 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01660853 0,09625634 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01660853 0,0959546 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01660853 0,09565474 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01660853 0,09535675 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01660853 0,09506061 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01660853 0,09476631 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01660853 0,09447382 ! adrenal gland development GO:0030325 5 5 0,000 0,01660853 0,09418313 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01660853 0,09389422 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01660853 0,09360708 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01660853 0,0933217 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01660853 0,09303804 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01660853 0,09275611 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01660853 0,09247588 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01660853 0,09219734 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01660853 0,09192047 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01660853 0,09164526 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01660853 0,09137169 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01660853 0,09109975 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01660853 0,09082943 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01660853 0,0905607 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01660853 0,09029356 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01660853 0,09002799 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01660853 0,08976398 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01660853 0,08950151 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01660853 0,08924057 ! response to ATP GO:0033198 5 5 0,000 0,01660853 0,08898115 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01660853 0,08872324 ! regulation of appetite GO:0032098 5 5 0,000 0,01660853 0,08846681 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01660853 0,08821186 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01660853 0,08795838 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01660853 0,08770635 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01660853 0,08745576 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01660853 0,0872066 ! receptor clustering GO:0043113 5 5 0,000 0,01660853 0,08695885 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01660853 0,08671251 ! fear response GO:0042596 5 5 0,000 0,01660853 0,08646756 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,01660853 0,08622399 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01660853 0,08598179 ! retinol metabolic process GO:0042572 5 5 0,000 0,01660853 0,08574094 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01660853 0,08550144 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01660853 0,08526328 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01660853 0,08502643 ! parturition GO:0007567 5 5 0,000 0,01660853 0,0847909 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01660853 0,08455668 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01660853 0,08432374 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01660853 0,08409208 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01660853 0,08386169 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01660853 0,08363256 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01660853 0,08340468 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01660853 0,08317803 ! response to UV-B GO:0010224 5 5 0,000 0,01660853 0,08295262 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01660853 0,08272842 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01660853 0,08250544 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01660853 0,08228365 ! interaction with symbiont GO:0051702 5 5 0,000 0,01660853 0,08206305 ! cellular extravasation GO:0045123 5 5 0,000 0,01660853 0,08184363 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01660853 0,08162538 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01660853 0,08140829 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01660853 0,08119235 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01660853 0,08097756 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01660853 0,0807639 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01660853 0,08055136 ! response to amine stimulus GO:0014075 5 5 0,000 0,01660853 0,08033994 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01660853 0,08012962 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01660853 0,07992041 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01660853 0,07971228 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01660853 0,07950524 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01660853 0,07929927 ! neuron recognition GO:0008038 5 5 0,000 0,01660853 0,07909436 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01660853 0,07889051 ! decidualization GO:0046697 5 5 0,000 0,01660853 0,0786877 ! hair follicle maturation GO:0048820 5 5 0,000 0,01660853 0,07848594 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01660853 0,07828521 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01660853 0,0780855 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01660853 0,07788681 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01660853 0,07768913 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01660853 0,07749245 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01660853 0,07729676 ! postreplication repair GO:0006301 5 5 0,000 0,01660853 0,07710206 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01660853 0,07690833 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01660853 0,07671558 ! histone methylation GO:0016571 5 5 0,000 0,01660853 0,07652379 ! DNA methylation GO:0006306 5 5 0,000 0,01660853 0,07633296 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01660853 0,07614308 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01660853 0,07595414 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01660853 0,07576613 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01660853 0,07557905 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01660853 0,0753929 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01660853 0,07520766 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01660853 0,07502332 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01660853 0,07483989 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01660853 0,07465736 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01660853 0,07447571 ! sterol catabolic process GO:0016127 5 5 0,000 0,01660853 0,07429494 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01660853 0,07411505 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01660853 0,07393603 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01660853 0,07375787 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01660853 0,07358057 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01660853 0,07340412 ! zymogen activation GO:0031638 5 5 0,000 0,01660853 0,07322851 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01660853 0,07305374 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01660853 0,0728798 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01660853 0,07270669 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01660853 0,0725344 ! nucleosome positioning GO:0016584 5 5 0,000 0,01660853 0,07236292 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01660853 0,07219226 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01660853 0,07202239 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01660853 0,07185333 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01660853 0,07168505 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01660853 0,07151756 ! NADPH regeneration GO:0006740 5 5 0,000 0,01660853 0,07135085 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01660853 0,07118492 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01660853 0,07101976 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01660853 0,07085536 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01660853 0,07069172 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01660853 0,07052884 ! sarcomere organization GO:0045214 5 5 0,000 0,01660853 0,0703667 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01660853 0,07020531 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01660853 0,07004466 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01660853 0,06988474 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01660853 0,06972555 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01660853 0,06956708 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01660853 0,06940933 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01660853 0,0692523 ! spleen development GO:0048536 5 5 0,000 0,01660853 0,06909597 ! male genitalia development GO:0030539 5 5 0,000 0,01660853 0,06894035 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01660853 0,06878543 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01660853 0,0686312 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01660853 0,06847767 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01660853 0,06832481 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01660853 0,06817264 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01660853 0,06802115 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01660853 0,06787032 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01660853 0,06772017 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01660853 0,06757068 ! ATP catabolic process GO:0006200 5 5 0,000 0,01660853 0,06742184 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01660853 0,06727366 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01660853 0,06712613 ! blastocyst formation GO:0001825 5 5 0,000 0,01660853 0,06697925 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01660853 0,06683301 ! embryonic gut development GO:0048566 5 5 0,000 0,01660853 0,0666874 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01660853 0,06654243 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01660853 0,06639808 ! activation of innate immune response GO:0002218 5 5 0,000 0,01660853 0,06625436 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01660853 0,06611127 ! catecholamine transport GO:0051937 5 5 0,000 0,01660853 0,06596879 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01660853 0,06582692 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01660853 0,06568566 ! muscle adaptation GO:0043500 5 5 0,000 0,01660853 0,065545 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01660853 0,06540495 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01660853 0,06526549 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01660853 0,06512663 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01660853 0,06498836 ! defense response to fungus GO:0050832 5 5 0,000 0,01660853 0,06485067 ! lysogeny GO:0030069 5 5 0,000 0,01660853 0,06471357 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01660853 0,06457704 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01660853 0,06444109 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01660853 0,06430571 ! response to nicotine GO:0035094 5 5 0,000 0,01660853 0,06417089 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01660853 0,06403665 ! mitochondrion localization GO:0051646 5 5 0,000 0,01660853 0,06390296 ! nucleus localization GO:0051647 5 5 0,000 0,01660853 0,06376983 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01660853 0,06363725 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,01735827 0,06637196 ! axonogenesis GO:0007409 66 62 1,000 0,01790069 0,0683043 ! protein import GO:0017038 62 62 1,000 0,01790069 0,06816318 ! regulation of secretion GO:0051046 65 63 1,000 0,01845031 0,0701112 ! glucose metabolic process GO:0006006 63 63 1,000 0,01845031 0,06996693 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,01900708 0,07193028 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,01900708 0,07178289 ! angiogenesis GO:0001525 65 64 1,000 0,01900708 0,07163609 ! regulation of hormone levels GO:0010817 66 65 1,000 0,01957094 0,0736107 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01989842 0,07468999 ! axon extension GO:0048675 7 6 0,000 0,01989842 0,07453818 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01989842 0,07438699 ! tRNA modification GO:0006400 6 6 0,000 0,01989842 0,07423641 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01989842 0,07408644 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01989842 0,07393707 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01989842 0,0737883 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01989842 0,07364013 ! regulation of S phase GO:0033261 6 6 0,000 0,01989842 0,07349256 ! myotube differentiation GO:0014902 6 6 0,000 0,01989842 0,07334557 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01989842 0,07319917 ! bone remodeling GO:0046849 6 6 0,000 0,01989842 0,07305336 ! N-glycan processing GO:0006491 6 6 0,000 0,01989842 0,07290812 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01989842 0,07276347 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01989842 0,07261938 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01989842 0,07247586 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01989842 0,07233291 ! RNA methylation GO:0001510 6 6 0,000 0,01989842 0,07219052 ! cartilage condensation GO:0001502 7 6 0,000 0,01989842 0,0720487 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01989842 0,07190742 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01989842 0,07176671 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,01989842 0,07162654 ! artery development GO:0060840 6 6 0,000 0,01989842 0,07148691 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01989842 0,07134783 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01989842 0,07120929 ! androgen metabolic process GO:0008209 6 6 0,000 0,01989842 0,07107129 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01989842 0,07093382 ! limbic system development GO:0021761 7 6 0,000 0,01989842 0,07079689 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01989842 0,07066048 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01989842 0,07052459 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01989842 0,07038923 ! pathogenesis GO:0009405 6 6 0,000 0,01989842 0,07025438 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01989842 0,07012005 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01989842 0,06998623 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01989842 0,06985293 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01989842 0,06972013 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01989842 0,06958783 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01989842 0,06945604 ! arginine metabolic process GO:0006525 6 6 0,000 0,01989842 0,06932474 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01989842 0,06919394 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01989842 0,06906363 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01989842 0,06893381 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01989842 0,06880448 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01989842 0,06867563 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01989842 0,06854726 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01989842 0,06841938 ! V(D)J recombination GO:0033151 6 6 0,000 0,01989842 0,06829197 ! focal adhesion formation GO:0048041 7 6 0,000 0,01989842 0,06816503 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01989842 0,06803856 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01989842 0,06791257 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01989842 0,06778704 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01989842 0,06766197 ! regulation of heart rate GO:0002027 6 6 0,000 0,01989842 0,06753736 ! lipid digestion GO:0044241 6 6 0,000 0,01989842 0,06741321 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01989842 0,06728952 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01989842 0,06716628 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01989842 0,06704349 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01989842 0,06692114 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01989842 0,06679925 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01989842 0,06667779 ! ruffle organization GO:0031529 6 6 0,000 0,01989842 0,06655678 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,01989842 0,06643621 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01989842 0,06631607 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01989842 0,06619637 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01989842 0,06607709 ! L-amino acid transport GO:0015807 6 6 0,000 0,01989842 0,06595825 ! bone mineralization GO:0030282 6 6 0,000 0,01989842 0,06583983 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01989842 0,06572184 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01989842 0,06560427 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01989842 0,06548712 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01989842 0,06537039 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01989842 0,06525407 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01989842 0,06513816 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01989842 0,06502267 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01989842 0,06490759 ! regulation of organ growth GO:0046620 6 6 0,000 0,01989842 0,06479291 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01989842 0,06467864 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01989842 0,06456477 ! response to dsRNA GO:0043331 6 6 0,000 0,01989842 0,06445129 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01989842 0,06433822 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01989842 0,06422555 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01989842 0,06411326 ! genitalia development GO:0048806 6 6 0,000 0,01989842 0,06400137 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01989842 0,06388987 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01989842 0,06377876 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01989842 0,06366803 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01989842 0,06355769 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01989842 0,06344773 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01989842 0,06333815 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01989842 0,06322894 ! erythrocyte development GO:0048821 6 6 0,000 0,01989842 0,06312011 ! renal water homeostasis GO:0003091 6 6 0,000 0,01989842 0,06301166 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01989842 0,06290358 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01989842 0,06279587 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01989842 0,06268852 ! ribosome assembly GO:0042255 6 6 0,000 0,01989842 0,06258155 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01989842 0,06247493 ! diencephalon development GO:0021536 6 6 0,000 0,01989842 0,06236868 ! fucose catabolic process GO:0019317 6 6 0,000 0,01989842 0,0622628 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01989842 0,06215727 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01989842 0,06205209 ! regulation of cell division GO:0051302 6 6 0,000 0,01989842 0,06194727 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01989842 0,06184281 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01989842 0,0617387 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01989842 0,06163494 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01989842 0,06153152 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01989842 0,06142845 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01989842 0,06132573 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01989842 0,06122335 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01989842 0,06112131 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01989842 0,06101961 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01989842 0,06091825 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01989842 0,06081722 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01989842 0,06071653 ! thymus development GO:0048538 6 6 0,000 0,01989842 0,06061618 ! lymph node development GO:0048535 6 6 0,000 0,01989842 0,06051615 ! organic cation transport GO:0015695 6 6 0,000 0,01989842 0,06041645 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01989842 0,06031708 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01989842 0,06021804 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01989842 0,06011932 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01989842 0,06002093 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01989842 0,05992285 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01989842 0,0598251 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01989842 0,05972767 ! alditol metabolic process GO:0019400 6 6 0,000 0,01989842 0,05963055 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01989842 0,05953374 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01989842 0,05943726 ! maternal placenta development GO:0001893 6 6 0,000 0,01989842 0,05934108 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01989842 0,05924521 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02071975 0,06159112 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,02071975 0,06149194 ! sensory perception of sound GO:0007605 71 69 1,000 0,02189635 0,06487937 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,02189635 0,06477523 ! response to nutrient levels GO:0031667 69 69 1,000 0,02189635 0,06467142 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,02189635 0,06456795 ! cell part morphogenesis GO:0032990 75 70 1,000 0,02249495 0,06622714 ! wound healing GO:0042060 74 70 1,000 0,02249495 0,06612151 ! muscle tissue development GO:0060537 72 70 1,000 0,02249495 0,06601622 ! translational elongation GO:0006414 71 71 1,000 0,02310035 0,06768513 ! respiratory burst GO:0045730 7 7 0,000 0,02317778 0,06780421 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02317778 0,06769675 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02317778 0,06758964 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02317778 0,06748286 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02317778 0,06737642 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02317778 0,06727032 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02317778 0,06716455 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02317778 0,06705911 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02317778 0,066954 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02317778 0,06684922 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02317778 0,06674477 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02317778 0,06664064 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02317778 0,06653684 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02317778 0,06643336 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02317778 0,0663302 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02317778 0,06622737 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02317778 0,06612485 ! axis specification GO:0009798 7 7 0,000 0,02317778 0,06602264 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02317778 0,06592076 ! visual behavior GO:0007632 7 7 0,000 0,02317778 0,06581919 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02317778 0,06571792 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02317778 0,06561698 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02317778 0,06551634 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02317778 0,065416 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02317778 0,06531598 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02317778 0,06521626 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02317778 0,06511685 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02317778 0,06501773 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02317778 0,06491892 ! digestive system development GO:0055123 7 7 0,000 0,02317778 0,06482041 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02317778 0,0647222 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02317778 0,06462428 ! protein targeting to ER GO:0045047 8 7 0,000 0,02317778 0,06452666 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02317778 0,06442934 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02317778 0,06433231 ! endoderm development GO:0007492 7 7 0,000 0,02317778 0,06423557 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02317778 0,06413912 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02317778 0,06404296 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02317778 0,06394708 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02317778 0,0638515 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02317778 0,0637562 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02317778 0,06366118 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02317778 0,06356645 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02317778 0,06347199 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02317778 0,06337782 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02317778 0,06328393 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02317778 0,06319031 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02317778 0,06309697 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02317778 0,06300391 ! UV protection GO:0009650 7 7 0,000 0,02317778 0,06291112 ! DNA integration GO:0015074 7 7 0,000 0,02317778 0,0628186 ! myofibril assembly GO:0030239 7 7 0,000 0,02317778 0,06272636 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02317778 0,06263439 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02317778 0,06254268 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02317778 0,06245124 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02317778 0,06236007 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02317778 0,06226917 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02317778 0,06217853 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02317778 0,06208816 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02317778 0,06199804 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02317778 0,06190819 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02317778 0,0618186 ! axon cargo transport GO:0008088 7 7 0,000 0,02317778 0,06172926 ! eating behavior GO:0042755 7 7 0,000 0,02317778 0,06164019 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02317778 0,06155137 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02317778 0,06146281 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02317778 0,0613745 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02317778 0,06128644 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02317778 0,06119864 ! cranial nerve development GO:0021545 7 7 0,000 0,02317778 0,06111109 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02317778 0,06102379 ! induction of an organ GO:0001759 7 7 0,000 0,02317778 0,06093673 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02317778 0,06084993 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02317778 0,06076337 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02317778 0,06067706 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02317778 0,06059099 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02317778 0,06050517 ! platelet activation GO:0030168 8 7 0,000 0,02317778 0,06041959 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02317778 0,06033425 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02317778 0,06024916 ! natural killer cell activation GO:0030101 7 7 0,000 0,02317778 0,0601643 ! NADP metabolic process GO:0006739 7 7 0,000 0,02317778 0,06007968 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02317778 0,0599953 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02317778 0,05991115 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02317778 0,05982724 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02317778 0,05974357 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02317778 0,05966013 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02317778 0,05957692 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02317778 0,05949394 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02317778 0,0594112 ! cell-cell recognition GO:0009988 8 7 0,000 0,02317778 0,05932868 ! hormone catabolic process GO:0042447 7 7 0,000 0,02317778 0,0592464 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02317778 0,05916434 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02317778 0,05908251 ! oxygen transport GO:0015671 7 7 0,000 0,02317778 0,0590009 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02317778 0,05891952 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02317778 0,05883836 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02317778 0,05875743 ! regulation of axon extension GO:0030516 7 7 0,000 0,02317778 0,05867672 ! cell killing GO:0001906 7 7 0,000 0,02317778 0,05859623 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02317778 0,05851596 ! adult feeding behavior GO:0008343 7 7 0,000 0,02317778 0,05843591 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02317778 0,05835608 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02317778 0,05827647 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02317778 0,05819707 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02317778 0,05811789 ! response to cold GO:0009409 7 7 0,000 0,02317778 0,05803893 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,02371251 0,05929736 ! response to oxidative stress GO:0006979 76 75 1,000 0,02558904 0,06390324 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02644665 0,06595557 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02644665 0,06586645 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02644665 0,06577756 ! positive regulation of translation GO:0045727 8 8 0,000 0,02644665 0,06568891 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02644665 0,0656005 ! superoxide anion generation GO:0042554 8 8 0,000 0,02644665 0,06551233 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02644665 0,06542439 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02644665 0,06533669 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02644665 0,06524922 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02644665 0,06516199 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02644665 0,06507499 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02644665 0,06498823 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02644665 0,06490169 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02644665 0,06481539 ! zinc ion transport GO:0006829 8 8 0,000 0,02644665 0,06472931 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02644665 0,06464346 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02644665 0,06455784 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02644665 0,06447245 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02644665 0,06438728 ! lipid localization GO:0010876 8 8 0,000 0,02644665 0,06430233 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02644665 0,06421762 ! response to cAMP GO:0051591 8 8 0,000 0,02644665 0,06413312 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02644665 0,06404884 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02644665 0,06396479 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02644665 0,06388096 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02644665 0,06379734 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02644665 0,06371395 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02644665 0,06363077 ! sensory perception of taste GO:0050909 8 8 0,000 0,02644665 0,06354781 ! organelle fusion GO:0048284 8 8 0,000 0,02644665 0,06346507 ! pancreas development GO:0031016 8 8 0,000 0,02644665 0,06338254 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02644665 0,06330022 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02644665 0,06321812 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02644665 0,06313623 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02644665 0,06305455 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02644665 0,06297309 ! sperm motility GO:0030317 8 8 0,000 0,02644665 0,06289183 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02644665 0,06281079 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02644665 0,06272995 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02644665 0,06264932 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02644665 0,0625689 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02644665 0,06248868 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02644665 0,06240867 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02644665 0,06232886 ! Golgi organization GO:0007030 8 8 0,000 0,02644665 0,06224926 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02644665 0,06216986 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02644665 0,06209066 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02644665 0,06201167 ! fructose metabolic process GO:0006000 8 8 0,000 0,02644665 0,06193287 ! mannose metabolic process GO:0006013 9 8 0,000 0,02644665 0,06185428 ! NAD metabolic process GO:0019674 8 8 0,000 0,02644665 0,06177588 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02644665 0,06169768 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02644665 0,06161968 ! response to fungus GO:0009620 8 8 0,000 0,02644665 0,06154188 ! stem cell differentiation GO:0048863 8 8 0,000 0,02644665 0,06146427 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02644665 0,06138686 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02644665 0,06130965 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02644665 0,06123263 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02644665 0,0611558 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02644665 0,06107916 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02644665 0,06100272 ! vasoconstriction GO:0042310 8 8 0,000 0,02644665 0,06092646 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02644665 0,0608504 ! muscle cell development GO:0055001 8 8 0,000 0,02644665 0,06077453 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02644665 0,06069884 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02644665 0,06062335 ! sensory perception of pain GO:0019233 8 8 0,000 0,02644665 0,06054804 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02644665 0,06047292 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02644665 0,06039798 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02644665 0,06032323 ! chromatin silencing GO:0006342 8 8 0,000 0,02644665 0,06024866 ! tissue regeneration GO:0042246 8 8 0,000 0,02644665 0,06017428 ! salivary gland development GO:0007431 8 8 0,000 0,02644665 0,06010009 ! T cell homeostasis GO:0043029 8 8 0,000 0,02644665 0,06002607 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02644665 0,05995224 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02644665 0,05987859 ! water homeostasis GO:0030104 8 8 0,000 0,02644665 0,05980512 ! cofactor transport GO:0051181 8 8 0,000 0,02644665 0,05973183 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02644665 0,05965871 ! acid secretion GO:0046717 8 8 0,000 0,02644665 0,05958578 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02644665 0,05951303 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02644665 0,05944045 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02644665 0,05936805 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02644665 0,05929583 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02644665 0,05922378 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02644665 0,05915191 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02644665 0,05908021 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02644665 0,05900868 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02644665 0,05893733 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02644665 0,05886615 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02644665 0,05879514 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02644665 0,0587243 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02644665 0,05865363 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02644665 0,05858314 ! developmental induction GO:0031128 8 8 0,000 0,02644665 0,05851281 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02644665 0,05844265 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02644665 0,05837266 ! actin filament polymerization GO:0030041 9 8 0,000 0,02644665 0,05830283 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02644665 0,05823318 ! peptide hormone processing GO:0016486 8 8 0,000 0,02644665 0,05816369 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02644665 0,05809436 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02644665 0,0580252 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,02687296 0,05889044 ! regulation of protein modification process GO:0031399 79 78 1,000 0,02752465 0,06024695 ! nuclear transport GO:0051169 79 79 1,000 0,02818277 0,06161428 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 0,02884726 0,06299231 ! tube development GO:0035295 83 81 1,000 0,0295181 0,06438089 ! lymphocyte activation GO:0046649 82 81 1,000 0,0295181 0,06430479 ! lactation GO:0007595 10 9 0,000 0,02970505 0,06463566 ! embryonic pattern specification GO:0009880 10 9 0,000 0,02970505 0,06455944 ! positive regulation of cell size GO:0045793 9 9 0,000 0,02970505 0,06448339 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,02970505 0,06440753 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,02970505 0,06433185 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,02970505 0,06425634 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,02970505 0,06418101 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,02970505 0,06410586 ! viral genome replication GO:0019079 9 9 0,000 0,02970505 0,06403088 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,02970505 0,06395608 ! copper ion transport GO:0006825 9 9 0,000 0,02970505 0,06388145 ! lipid phosphorylation GO:0046834 9 9 0,000 0,02970505 0,063807 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,02970505 0,06373271 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,02970505 0,06365861 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,02970505 0,06358467 ! RNA polyadenylation GO:0043631 9 9 0,000 0,02970505 0,06351091 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,02970505 0,06343731 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,02970505 0,06336389 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,02970505 0,06329064 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,02970505 0,06321755 ! phospholipid efflux GO:0033700 9 9 0,000 0,02970505 0,06314464 ! response to alkaloid GO:0043279 10 9 0,000 0,02970505 0,06307189 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,02970505 0,06299931 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,02970505 0,0629269 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,02970505 0,06285465 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,02970505 0,06278257 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,02970505 0,06271065 ! response to ethanol GO:0045471 9 9 0,000 0,02970505 0,0626389 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,02970505 0,06256732 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,02970505 0,06249589 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,02970505 0,06242463 ! methionine metabolic process GO:0006555 9 9 0,000 0,02970505 0,06235353 ! glutamine metabolic process GO:0006541 9 9 0,000 0,02970505 0,0622826 ! cerebral cortex development GO:0021987 9 9 0,000 0,02970505 0,06221182 ! response to osmotic stress GO:0006970 9 9 0,000 0,02970505 0,06214121 ! pigmentation during development GO:0048066 9 9 0,000 0,02970505 0,06207075 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,02970505 0,06200045 ! central nervous system neuron development GO:0021954 10 9 0,000 0,02970505 0,06193032 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,02970505 0,06186034 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,02970505 0,06179052 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,02970505 0,06172086 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,02970505 0,06165135 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,02970505 0,061582 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,02970505 0,06151281 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,02970505 0,06144377 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,02970505 0,06137489 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,02970505 0,06130616 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,02970505 0,06123759 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,02970505 0,06116916 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,02970505 0,06110089 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,02970505 0,06103278 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,02970505 0,06096481 ! DNA replication initiation GO:0006270 9 9 0,000 0,02970505 0,060897 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,02970505 0,06082934 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,02970505 0,06076182 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,02970505 0,06069446 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,02970505 0,06062724 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,02970505 0,06056018 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,02970505 0,06049326 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,02970505 0,06042649 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,02970505 0,06035987 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,02970505 0,06029339 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,02970505 0,06022706 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,02970505 0,06016088 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,02970505 0,06009484 ! collagen catabolic process GO:0030574 9 9 0,000 0,02970505 0,06002895 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,02970505 0,0599632 ! purine base metabolic process GO:0006144 9 9 0,000 0,02970505 0,05989759 ! gas transport GO:0015669 9 9 0,000 0,02970505 0,05983213 ! cholesterol efflux GO:0033344 9 9 0,000 0,02970505 0,05976681 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,02970505 0,05970164 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,02970505 0,0596366 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,02970505 0,05957171 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,02970505 0,05950696 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,02970505 0,05944235 ! defense response to virus GO:0051607 9 9 0,000 0,02970505 0,05937788 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,02970505 0,05931354 ! actin filament-based movement GO:0030048 9 9 0,000 0,02970505 0,05924935 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,02970505 0,0591853 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,03087857 0,06145703 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,03226384 0,06414482 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03295301 0,0654444 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03295301 0,06537396 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03295301 0,06530366 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03295301 0,06523352 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03295301 0,06516353 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03295301 0,06509368 ! neuron maturation GO:0042551 10 10 0,000 0,03295301 0,06502399 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03295301 0,06495444 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03295301 0,06488505 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03295301 0,0648158 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03295301 0,0647467 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03295301 0,06467775 ! hormone secretion GO:0046879 10 10 0,000 0,03295301 0,06460894 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03295301 0,06454028 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03295301 0,06447177 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03295301 0,0644034 ! inositol metabolic process GO:0006020 10 10 0,000 0,03295301 0,06433518 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03295301 0,0642671 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03295301 0,06419916 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03295301 0,06413137 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03295301 0,06406372 ! glial cell development GO:0021782 10 10 0,000 0,03295301 0,06399621 ! phototransduction GO:0007602 11 10 0,000 0,03295301 0,06392885 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03295301 0,06386163 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03295301 0,06379454 ! fat cell differentiation GO:0045444 10 10 0,000 0,03295301 0,0637276 ! myoblast differentiation GO:0045445 10 10 0,000 0,03295301 0,0636608 ! centrosome cycle GO:0007098 10 10 0,000 0,03295301 0,06359414 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03295301 0,06352762 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03295301 0,06346124 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03295301 0,063395 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03295301 0,06332889 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03295301 0,06326292 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03295301 0,06319709 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03295301 0,0631314 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03295301 0,06306584 ! plasma membrane organization GO:0007009 10 10 0,000 0,03295301 0,06300042 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03295301 0,06293514 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03295301 0,06286999 ! lysosomal transport GO:0007041 10 10 0,000 0,03295301 0,06280497 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03295301 0,06274009 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03295301 0,06267534 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03295301 0,06261073 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03295301 0,06254625 ! exocrine system development GO:0035272 10 10 0,000 0,03295301 0,0624819 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03295301 0,06241768 ! neuromuscular junction development GO:0007528 10 10 0,000 0,03295301 0,0623536 ! embryo implantation GO:0007566 11 10 0,000 0,03295301 0,06228965 ! regulation of protein binding GO:0043393 11 10 0,000 0,03295301 0,06222583 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03295301 0,06216213 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03295301 0,06209857 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03295301 0,06203514 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03295301 0,06197184 ! protein export from nucleus GO:0006611 10 10 0,000 0,03295301 0,06190867 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03295301 0,06184563 ! cytolysis GO:0019835 10 10 0,000 0,03295301 0,06178271 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03295301 0,06171992 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03295301 0,06165726 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03295301 0,06159473 ! histone deacetylation GO:0016575 10 10 0,000 0,03295301 0,06153233 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03295301 0,06147005 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03295301 0,06140789 ! gland morphogenesis GO:0022612 10 10 0,000 0,03295301 0,06134586 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03295301 0,06128396 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03295301 0,06122218 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03295301 0,06116053 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03295301 0,061099 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03295301 0,06103759 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03295301 0,06097631 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03295301 0,06091515 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03295301 0,06085411 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03295301 0,0607932 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03295301 0,06073241 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03295301 0,06067173 ! nerve development GO:0021675 10 10 0,000 0,03295301 0,06061118 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03295301 0,06055075 ! gut development GO:0048565 10 10 0,000 0,03295301 0,06049044 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03295301 0,06043025 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03295301 0,06037018 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03295301 0,06031023 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03295301 0,0602504 ! protein stabilization GO:0050821 10 10 0,000 0,03295301 0,06019069 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,03296565 0,06015415 ! hexose metabolic process GO:0019318 87 86 1,000 0,03296565 0,06009465 ! protein secretion GO:0009306 11 11 0,000 0,03619058 0,06590834 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03619058 0,06584328 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,03619058 0,06577834 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03619058 0,06571354 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03619058 0,06564886 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03619058 0,06558431 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03619058 0,06551988 ! skin development GO:0043588 11 11 0,000 0,03619058 0,06545558 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03619058 0,06539141 ! signal complex assembly GO:0007172 11 11 0,000 0,03619058 0,06532737 ! microtubule-based transport GO:0010970 11 11 0,000 0,03619058 0,06526344 ! endothelial cell migration GO:0043542 11 11 0,000 0,03619058 0,06519965 ! peroxisomal transport GO:0043574 11 11 0,000 0,03619058 0,06513598 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03619058 0,06507243 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,03619058 0,06500901 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03619058 0,06494571 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03619058 0,06488253 ! T cell proliferation GO:0042098 11 11 0,000 0,03619058 0,06481948 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03619058 0,06475654 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03619058 0,06469373 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03619058 0,06463105 ! spinal cord development GO:0021510 11 11 0,000 0,03619058 0,06456848 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03619058 0,06450604 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03619058 0,06444371 ! digestive system process GO:0022600 11 11 0,000 0,03619058 0,06438151 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03619058 0,06431942 ! fucose metabolic process GO:0006004 11 11 0,000 0,03619058 0,06425746 ! membrane budding GO:0006900 11 11 0,000 0,03619058 0,06419561 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03619058 0,06413388 ! monoamine transport GO:0015844 11 11 0,000 0,03619058 0,06407228 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03619058 0,06401079 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03619058 0,06394942 ! body fluid secretion GO:0007589 11 11 0,000 0,03619058 0,06388816 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03619058 0,06382702 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03619058 0,063766 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03619058 0,0637051 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,03619058 0,06364431 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03619058 0,06358364 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03619058 0,06352309 ! oogenesis GO:0048477 11 11 0,000 0,03619058 0,06346265 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03619058 0,06340232 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03619058 0,06334211 ! vitamin transport GO:0051180 11 11 0,000 0,03619058 0,06328201 ! muscle maintenance GO:0046716 12 11 0,000 0,03619058 0,06322203 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03619058 0,06316216 ! hindbrain development GO:0030902 11 11 0,000 0,03619058 0,0631024 ! steroid catabolic process GO:0006706 11 11 0,000 0,03619058 0,06304276 ! endocrine process GO:0050886 11 11 0,000 0,03619058 0,06298323 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03619058 0,06292381 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03619058 0,06286451 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03619058 0,06280531 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03619058 0,06274623 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,03619058 0,06268726 ! DNA replication GO:0006260 91 91 1,000 0,03656476 0,06327592 ! blood vessel development GO:0001568 95 94 1,000 0,03879468 0,06707185 ! pattern specification process GO:0007389 96 94 1,000 0,03879468 0,06700899 ! epidermis development GO:0008544 94 94 1,000 0,03879468 0,06694625 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,03941778 0,06795787 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,03941778 0,06789436 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,03941778 0,06783097 ! initiation of viral infection GO:0019059 12 12 0,000 0,03941778 0,06776769 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,03941778 0,06770453 ! iron ion transport GO:0006826 13 12 0,000 0,03941778 0,06764149 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,03941778 0,06757857 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,03941778 0,06751577 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,03941778 0,06745308 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,03941778 0,06739051 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,03941778 0,06732805 ! collagen metabolic process GO:0032963 12 12 0,000 0,03941778 0,06726571 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,03941778 0,06720348 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,03941778 0,06714137 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,03941778 0,06707938 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,03941778 0,06701749 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,03941778 0,06695573 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,03941778 0,06689407 ! actomyosin structure organization GO:0031032 12 12 0,000 0,03941778 0,06683253 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,03941778 0,06677111 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,03941778 0,06670979 ! retinoid metabolic process GO:0001523 12 12 0,000 0,03941778 0,06664859 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,03941778 0,0665875 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,03941778 0,06652652 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,03941778 0,06646566 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,03941778 0,0664049 ! acute-phase response GO:0006953 12 12 0,000 0,03941778 0,06634426 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,03941778 0,06628373 ! vacuolar transport GO:0007034 12 12 0,000 0,03941778 0,0662233 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,03941778 0,06616299 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,03941778 0,06610279 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,03941778 0,0660427 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,03941778 0,06598271 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,03941778 0,06592284 ! male gonad development GO:0008584 12 12 0,000 0,03941778 0,06586307 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,03941778 0,06580341 ! renal system process GO:0003014 12 12 0,000 0,03941778 0,06574386 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,03941778 0,06568442 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,03941778 0,06562508 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,03941778 0,06556585 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,03941778 0,06550673 ! pallium development GO:0021543 13 12 0,000 0,03941778 0,06544772 ! cell fate determination GO:0001709 12 12 0,000 0,03941778 0,06538881 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,03941778 0,06533 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,03941778 0,06527131 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,03941778 0,06521272 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,03941778 0,06515423 ! detection of light stimulus GO:0009583 13 12 0,000 0,03941778 0,06509585 ! synaptogenesis GO:0007416 12 12 0,000 0,03941778 0,06503757 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,03941778 0,0649794 ! hormone transport GO:0009914 12 12 0,000 0,03941778 0,06492133 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,03941778 0,06486336 ! heme biosynthetic process GO:0006783 12 12 0,000 0,03941778 0,0648055 ! spermatid differentiation GO:0048515 13 12 0,000 0,03941778 0,06474774 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,03941778 0,06469008 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,03941778 0,06463253 ! neural tube closure GO:0001843 13 12 0,000 0,03941778 0,06457508 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,03941778 0,06451773 ! negative regulation of translation GO:0017148 12 12 0,000 0,03941778 0,06446048 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,03941778 0,06440334 ! regulation of cell growth GO:0001558 97 96 1,000 0,04030992 0,06580264 ! vasculature development GO:0001944 97 96 1,000 0,04030992 0,06574441 ! ectoderm development GO:0007398 99 99 1,000 0,04262487 0,06945856 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04263464 0,06941311 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04263464 0,06935184 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04263464 0,06929068 ! phenol metabolic process GO:0018958 13 13 0,000 0,04263464 0,06922964 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04263464 0,06916869 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04263464 0,06910786 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04263464 0,06904713 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04263464 0,06898651 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04263464 0,068926 ! regeneration GO:0031099 13 13 0,000 0,04263464 0,06886559 ! keratinization GO:0031424 13 13 0,000 0,04263464 0,06880529 ! post-embryonic development GO:0009791 14 13 0,000 0,04263464 0,06874509 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04263464 0,068685 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04263464 0,06862501 ! vasculogenesis GO:0001570 13 13 0,000 0,04263464 0,06856513 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04263464 0,06850535 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04263464 0,06844568 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04263464 0,06838611 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04263464 0,06832664 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04263464 0,06826728 ! autophagy GO:0006914 13 13 0,000 0,04263464 0,06820802 ! receptor metabolic process GO:0043112 14 13 0,000 0,04263464 0,06814886 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04263464 0,06808981 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04263464 0,06803085 ! ureteric bud development GO:0001657 13 13 0,000 0,04263464 0,067972 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04263464 0,06791326 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04263464 0,06785461 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04263464 0,06779606 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04263464 0,06773762 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04263464 0,06767927 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04263464 0,06762103 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04263464 0,06756289 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04263464 0,06750484 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04263464 0,0674469 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04263464 0,06738905 ! vasodilation GO:0042311 14 13 0,000 0,04263464 0,06733131 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04263464 0,06727366 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04263464 0,06721611 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04263464 0,06715866 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04263464 0,06710131 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04263464 0,06704406 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04263464 0,0669869 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04263464 0,06692984 ! immunoglobulin production GO:0002377 13 13 0,000 0,04263464 0,06687288 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04263464 0,06681602 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04263464 0,06675925 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,04263464 0,06670258 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04263464 0,066646 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04263464 0,06658952 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04263464 0,06653314 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04263464 0,06647685 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04263464 0,06642066 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04263464 0,06636456 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04263464 0,06630855 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04263464 0,06625264 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04263464 0,06619683 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04263464 0,06614111 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04263464 0,06608548 ! blastocyst development GO:0001824 13 13 0,000 0,04263464 0,06602995 ! telomere organization GO:0032200 13 13 0,000 0,04263464 0,06597451 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04263464 0,06591916 ! regulation of amine transport GO:0051952 13 13 0,000 0,04263464 0,0658639 ! tissue homeostasis GO:0001894 13 13 0,000 0,04263464 0,06580874 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04263464 0,06575367 ! muscle organ development GO:0007517 102 100 1,000 0,04340757 0,06688977 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,04340757 0,06683388 ! neuron fate commitment GO:0048663 14 14 0,000 0,04584119 0,07052197 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04584119 0,07046315 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04584119 0,07040443 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04584119 0,07034581 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,04584119 0,07028728 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,04584119 0,07022886 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04584119 0,07017053 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04584119 0,07011229 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,04584119 0,07005416 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04584119 0,06999612 ! vesicle docking GO:0048278 14 14 0,000 0,04584119 0,06993817 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04584119 0,06988033 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04584119 0,06982257 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,04584119 0,06976492 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04584119 0,06970736 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04584119 0,06964989 ! hair cycle GO:0042633 14 14 0,000 0,04584119 0,06959252 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04584119 0,06953524 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,04584119 0,06947805 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04584119 0,06942097 ! lysosome organization GO:0007040 14 14 0,000 0,04584119 0,06936397 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,04584119 0,06930707 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,04584119 0,06925026 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04584119 0,06919354 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,04584119 0,06913692 ! primary neural tube formation GO:0014020 15 14 0,000 0,04584119 0,06908039 ! peptide cross-linking GO:0018149 14 14 0,000 0,04584119 0,06902395 ! regulation of behavior GO:0050795 14 14 0,000 0,04584119 0,0689676 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04584119 0,06891135 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04584119 0,06885519 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04584119 0,06879912 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,04584119 0,06874314 ! formation of primary germ layer GO:0001704 14 14 0,000 0,04584119 0,06868725 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,04584119 0,06863145 ! collagen fibril organization GO:0030199 14 14 0,000 0,04584119 0,06857574 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04584119 0,06852013 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04584119 0,0684646 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04584119 0,06840916 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,04584119 0,06835381 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04584119 0,06829856 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04584119 0,06824339 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04584119 0,06818831 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04584119 0,06813332 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,04903747 0,07282519 ! positive regulation of ossification GO:0045778 15 15 0,000 0,04903747 0,07276655 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,04903747 0,07270801 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,04903747 0,07264956 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,04903747 0,07259121 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,04903747 0,07253295 ! response to vitamin GO:0033273 15 15 0,000 0,04903747 0,07247479 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,04903747 0,07241671 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,04903747 0,07235873 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,04903747 0,07230085 ! ovarian follicle development GO:0001541 15 15 0,000 0,04903747 0,07224305 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,04903747 0,07218535 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,04903747 0,07212774 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,04903747 0,07207022 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,04903747 0,07201279 ! heme metabolic process GO:0042168 15 15 0,000 0,04903747 0,07195546 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,04903747 0,07189822 ! chromosome condensation GO:0030261 15 15 0,000 0,04903747 0,07184106 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,04903747 0,071784 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,04903747 0,07172703 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,04903747 0,07167015 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,04903747 0,07161336 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,04903747 0,07155666 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,04903747 0,07150005 ! phospholipid transport GO:0015914 15 15 0,000 0,04903747 0,07144352 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,04903747 0,07138709 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,04903747 0,07133075 ! glutathione metabolic process GO:0006749 16 15 0,000 0,04903747 0,07127449 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,04903747 0,07121833 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,04903747 0,07116225 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,04903747 0,07110626 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,04903747 0,07105036 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,04903747 0,07099455 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,04903747 0,07093882 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,04903747 0,07088318 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05222351 0,07542941 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05222351 0,07537034 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05222351 0,07531136 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05222351 0,07525248 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05222351 0,07519369 ! learning GO:0007612 16 16 0,000 0,05222351 0,07513499 ! circadian rhythm GO:0007623 16 16 0,000 0,05222351 0,07507638 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05222351 0,07501787 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05222351 0,07495944 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,05222351 0,07490111 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05222351 0,07484286 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05222351 0,07478471 ! vesicle targeting GO:0006903 17 16 0,000 0,05222351 0,07472665 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05222351 0,07466867 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05222351 0,07461079 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05222351 0,074553 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05222351 0,0744953 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05222351 0,07443768 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05222351 0,07438016 ! cell fate specification GO:0001708 16 16 0,000 0,05222351 0,07432272 ! pentose metabolic process GO:0019321 16 16 0,000 0,05222351 0,07426537 ! fatty acid transport GO:0015908 16 16 0,000 0,05222351 0,07420811 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05222351 0,07415094 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05222351 0,07409386 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05222351 0,07403686 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05222351 0,07397996 ! polyol metabolic process GO:0019751 16 16 0,000 0,05222351 0,07392314 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05222351 0,0738664 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05222351 0,07380976 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05222351 0,0737532 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05222351 0,07369672 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05222351 0,07364034 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05222351 0,07358404 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,05539933 0,07799921 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,05539933 0,07793967 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,05539933 0,07788022 ! myelination GO:0042552 17 17 0,000 0,05539933 0,07782086 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,05539933 0,07776159 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,05539933 0,07770241 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,05539933 0,07764332 ! leukocyte adhesion GO:0007159 17 17 0,000 0,05539933 0,07758432 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,05539933 0,07752541 ! sensory perception of smell GO:0007608 17 17 0,000 0,05539933 0,07746659 ! glucose transport GO:0015758 17 17 0,000 0,05539933 0,07740786 ! cell junction assembly GO:0034329 18 17 0,000 0,05539933 0,07734922 ! tissue remodeling GO:0048771 17 17 0,000 0,05539933 0,07729066 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,05539933 0,0772322 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,05539933 0,07717382 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,05539933 0,07711553 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,05539933 0,07705733 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,05539933 0,07699922 ! neural crest cell development GO:0014032 19 17 0,000 0,05539933 0,0769412 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,05539933 0,07688326 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,05539933 0,07682541 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,05539933 0,07676764 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,05539933 0,07670997 ! pigmentation GO:0043473 17 17 0,000 0,05539933 0,07665238 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,05539933 0,07659487 ! adult locomotory behavior GO:0008344 17 17 0,000 0,05539933 0,07653746 ! embryonic organ development GO:0048568 17 17 0,000 0,05539933 0,07648012 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,05539933 0,07642288 ! liver development GO:0001889 17 17 0,000 0,05539933 0,07636572 ! gene silencing GO:0016458 17 17 0,000 0,05539933 0,07630864 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,05856497 0,08060885 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,05856497 0,08054869 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,05856497 0,08048863 ! meiosis I GO:0007127 18 18 0,000 0,05856497 0,08042865 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,05856497 0,08036876 ! membrane docking GO:0022406 18 18 0,000 0,05856497 0,08030896 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,05856497 0,08024926 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,05856497 0,08018963 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,05856497 0,0801301 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,05856497 0,08007066 ! hexose transport GO:0008645 18 18 0,000 0,05856497 0,0800113 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,05856497 0,07995204 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,05856497 0,07989286 ! ceramide metabolic process GO:0006672 18 18 0,000 0,05856497 0,07983376 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,05856497 0,07977476 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,05856497 0,07971584 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,05856497 0,07965701 ! ensheathment of neurons GO:0007272 18 18 0,000 0,05856497 0,07959827 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,05856497 0,07953961 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,05856497 0,07948104 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,05856497 0,07942255 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,05856497 0,07936415 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06172047 0,08357886 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06172047 0,08351749 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,06172047 0,08345622 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06172047 0,08339503 ! feeding behavior GO:0007631 19 19 0,000 0,06172047 0,08333394 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06172047 0,08327293 ! peroxisome organization GO:0007031 19 19 0,000 0,06172047 0,08321202 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06172047 0,08315119 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06172047 0,08309045 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06172047 0,0830298 ! metanephros development GO:0001656 19 19 0,000 0,06172047 0,08296924 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06172047 0,08290876 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06172047 0,08284838 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06172047 0,08278808 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06172047 0,08272787 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06172047 0,08266775 ! peripheral nervous system development GO:0007422 19 19 0,000 0,06172047 0,08260772 ! regulation of protein stability GO:0031647 19 19 0,000 0,06172047 0,08254777 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06172047 0,08248791 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06172047 0,08242813 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06172047 0,08236845 ! eye morphogenesis GO:0048592 19 19 0,000 0,06172047 0,08230885 ! regulation of cell shape GO:0008360 21 19 0,000 0,06172047 0,08224933 ! placenta development GO:0001890 19 19 0,000 0,06172047 0,0821899 ! response to heat GO:0009408 19 19 0,000 0,06172047 0,08213056 ! vesicle localization GO:0051648 20 19 0,000 0,06172047 0,0820713 ! regulation of muscle development GO:0048634 21 20 0,000 0,06486585 0,0861916 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,06486585 0,08612951 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,06486585 0,0860675 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,06486585 0,08600558 ! neural tube development GO:0021915 21 20 0,000 0,06486585 0,08594375 ! nucleus organization GO:0006997 20 20 0,000 0,06486585 0,08588201 ! phagocytosis GO:0006909 21 20 0,000 0,06486585 0,08582036 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06486585 0,08575879 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06486585 0,08569732 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,06486585 0,08563593 ! chromatin remodeling GO:0006338 20 20 0,000 0,06486585 0,08557463 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06486585 0,08551342 ! lipid oxidation GO:0034440 20 20 0,000 0,06486585 0,08545229 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06486585 0,08539125 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,06486585 0,0853303 ! RNA modification GO:0009451 20 20 0,000 0,06486585 0,08526944 ! single fertilization GO:0007338 21 20 0,000 0,06486585 0,08520866 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06486585 0,08514797 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,06800114 0,08920007 ! mRNA catabolic process GO:0006402 21 21 0,000 0,06800114 0,08913662 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,06800114 0,08907327 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,06800114 0,08901001 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,06800114 0,08894684 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,06800114 0,08888375 ! Notch signaling pathway GO:0007219 22 21 0,000 0,06800114 0,08882076 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,06800114 0,08875786 ! ear morphogenesis GO:0042471 21 21 0,000 0,06800114 0,08869504 ! organic anion transport GO:0015711 21 21 0,000 0,06800114 0,08863231 ! cholesterol transport GO:0030301 21 21 0,000 0,06800114 0,08856968 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,06800114 0,08850713 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,06800114 0,08844467 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,06800114 0,08838229 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,06800114 0,08832001 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,06800114 0,08825781 ! regulation of proteolysis GO:0030162 21 21 0,000 0,06800114 0,0881957 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,06800114 0,08813368 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,06800114 0,08807175 ! RNA export from nucleus GO:0006405 22 22 0,000 0,07112637 0,0920547 ! sister chromatid segregation GO:0000819 22 22 0,000 0,07112637 0,0919901 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,07112637 0,09192559 ! regulation of ion transport GO:0043269 22 22 0,000 0,07112637 0,09186118 ! odontogenesis GO:0042476 22 22 0,000 0,07112637 0,09179685 ! cell junction organization GO:0034330 23 22 0,000 0,07112637 0,09173261 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,07112637 0,09166846 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,07112637 0,0916044 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,07112637 0,09154043 ! ovulation cycle process GO:0022602 22 22 0,000 0,07112637 0,09147655 ! spindle organization GO:0007051 22 22 0,000 0,07112637 0,09141276 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,07112637 0,09134906 ! cell chemotaxis GO:0060326 23 22 0,000 0,07112637 0,09128544 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,07112637 0,09122192 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,07112637 0,09115848 ! male sex differentiation GO:0046661 22 22 0,000 0,07112637 0,09109513 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,07112637 0,09103187 ! biopolymer methylation GO:0043414 22 22 0,000 0,07112637 0,0909687 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,07112637 0,09090562 ! detection of external stimulus GO:0009581 23 22 0,000 0,07112637 0,09084262 ! neuron migration GO:0001764 22 22 0,000 0,07112637 0,09077971 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,07112637 0,09071688 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,07112637 0,09065415 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,07112637 0,0905915 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,07112637 0,09052893 ! aerobic respiration GO:0009060 22 22 0,000 0,07112637 0,09046646 ! cytokine production GO:0001816 22 22 0,000 0,07112637 0,09040407 ! cytokinesis GO:0000910 23 22 0,000 0,07112637 0,09034176 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,07112637 0,09027954 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07424158 0,09416877 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07424158 0,09410401 ! viral infectious cycle GO:0019058 23 23 0,000 0,07424158 0,09403933 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07424158 0,09397474 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,07424158 0,09391024 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,07424158 0,09384583 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07424158 0,09378151 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07424158 0,09371728 ! endocrine system development GO:0035270 23 23 0,000 0,07424158 0,09365313 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07424158 0,09358907 ! female gonad development GO:0008585 23 23 0,000 0,07424158 0,0935251 ! lipid homeostasis GO:0055088 23 23 0,000 0,07424158 0,09346122 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07424158 0,09339742 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,07424158 0,09333371 ! regulation of action potential GO:0001508 24 24 0,000 0,07734679 0,09717119 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,07734679 0,09710499 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,07734679 0,09703889 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,07734679 0,09697288 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,07734679 0,09690696 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,07734679 0,09684112 ! ovulation cycle GO:0042698 24 24 0,000 0,07734679 0,09677538 ! fertilization GO:0009566 25 24 0,000 0,07734679 0,09670972 ! maintenance of protein location GO:0045185 25 24 0,000 0,07734679 0,09664416 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,07734679 0,09657868 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,07734679 0,09651329 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,07734679 0,09644799 ! glucan metabolic process GO:0044042 25 24 0,000 0,07734679 0,09638278 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,08044204 0,10017208 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,08044204 0,10010444 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,08044204 0,10003689 ! cellular component disassembly GO:0022411 26 25 0,000 0,08044204 0,09996944 ! endosome transport GO:0016197 25 25 0,000 0,08044204 0,09990207 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,08044204 0,0998348 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,08044204 0,09976761 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,08044204 0,09970052 ! excretion GO:0007588 25 25 0,000 0,08044204 0,09963352 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,08044204 0,09956661 ! gastrulation GO:0007369 25 25 0,000 0,08044204 0,09949978 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,08044204 0,09943305 ! regulation of endocytosis GO:0030100 25 25 0,000 0,08044204 0,0993664 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,08044204 0,09929985 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,08044204 0,09923338 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,08044204 0,09916701 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08352735 0,10290168 ! glycolysis GO:0006096 26 26 0,000 0,08352735 0,10283294 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,08352735 0,10276429 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,08352735 0,10269574 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08352735 0,10262727 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,08352735 0,1025589 ! cellular defense response GO:0006968 26 26 0,000 0,08352735 0,10249062 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08352735 0,10242243 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,08352735 0,10235433 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08352735 0,10228632 ! germ cell development GO:0007281 27 26 0,000 0,08352735 0,1022184 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,08352735 0,10215057 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,08352735 0,10208283 ! maintenance of location in cell GO:0051651 27 26 0,000 0,08352735 0,10201518 ! synapse organization GO:0050808 26 26 0,000 0,08352735 0,10194762 ! chloride transport GO:0006821 27 27 0,000 0,08660276 0,1056313 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,08660276 0,10556144 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,08660276 0,10549167 ! learning or memory GO:0007611 28 27 0,000 0,08660276 0,10542199 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,08660276 0,10535241 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,08660276 0,10528291 ! peptide metabolic process GO:0006518 29 27 0,000 0,08660276 0,10521351 ! mesenchymal cell development GO:0014031 29 27 0,000 0,08660276 0,1051442 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,08660276 0,10507498 ! defense response to bacterium GO:0042742 27 27 0,000 0,08660276 0,10500585 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,08660276 0,10493681 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,08660276 0,10486787 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,0896683 0,10850866 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,0896683 0,10843746 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,0896683 0,10836635 ! carbohydrate transport GO:0008643 28 28 0,000 0,0896683 0,10829534 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,0896683 0,10822442 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,0896683 0,10815359 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,0896683 0,10808285 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,0896683 0,10801221 ! developmental growth GO:0048589 28 28 0,000 0,0896683 0,10794166 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,0896683 0,1078712 ! cartilage development GO:0051216 29 28 0,000 0,0896683 0,10780084 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,092724 0,11140178 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,092724 0,1113292 ! leukocyte migration GO:0050900 30 29 0,000 0,092724 0,11125673 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,092724 0,11118434 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,092724 0,11111205 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,092724 0,11103985 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,092724 0,11096775 ! tRNA processing GO:0008033 29 29 0,000 0,092724 0,11089574 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,092724 0,11082382 ! adult behavior GO:0030534 30 29 0,000 0,092724 0,110752 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,092724 0,11068027 ! transition metal ion transport GO:0000041 31 30 0,000 0,09576988 0,114242 ! RNA catabolic process GO:0006401 30 30 0,000 0,09576988 0,11416811 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,09576988 0,11409431 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09576988 0,1140206 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09576988 0,11394699 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09576988 0,11387348 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,09576988 0,11380006 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,09576988 0,11372674 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,09576988 0,1136535 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,09576988 0,11358037 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09576988 0,11350733 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,09576988 0,11343438 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,09576988 0,11336152 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09576988 0,11328876 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09576988 0,1132161 ! vesicle organization GO:0016050 30 30 0,000 0,09576988 0,11314352 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09576988 0,11307104 ! establishment of organelle localization GO:0051656 31 30 0,000 0,09576988 0,11299865 ! regulation of translational initiation GO:0006446 31 31 0,000 0,09880598 0,11650635 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,09880598 0,11643186 ! membrane fusion GO:0006944 31 31 0,000 0,09880598 0,11635746 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,09880598 0,11628316 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,09880598 0,11620895 ! ion transmembrane transport GO:0034220 31 31 0,000 0,09880598 0,11613484 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,09880598 0,11606082 ! digestion GO:0007586 31 31 0,000 0,09880598 0,1159869 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,09880598 0,11591307 ! regulation of heart contraction GO:0008016 31 31 0,000 0,09880598 0,11583933 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,09880598 0,11576569 ! camera-type eye development GO:0043010 31 31 0,000 0,09880598 0,11569214 ! extracellular matrix organization GO:0030198 31 31 0,000 0,09880598 0,11561868 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,09880598 0,11554532 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,09880598 0,11547205 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,09880598 0,11539888 ! cell redox homeostasis GO:0045454 32 32 0,000 0,10183233 0,11885813 ! muscle fiber development GO:0048747 32 32 0,000 0,10183233 0,1187829 ! glucose catabolic process GO:0006007 32 32 0,000 0,10183233 0,11870777 ! lipid modification GO:0030258 32 32 0,000 0,10183233 0,11863274 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,10183233 0,11855779 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,10183233 0,11848295 ! cell maturation GO:0048469 32 32 0,000 0,10183233 0,11840819 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,10183233 0,11833354 ! nuclear export GO:0051168 32 32 0,000 0,10183233 0,11825897 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,10183233 0,1181845 ! kidney development GO:0001822 32 32 0,000 0,10183233 0,11811012 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,10183233 0,11803584 ! maintenance of location GO:0051235 33 32 0,000 0,10183233 0,11796165 ! amino acid transport GO:0006865 33 33 0,000 0,10484896 0,12137979 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,10484896 0,1213036 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10484896 0,1212275 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,10484896 0,12115149 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,10484896 0,12107558 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,10484896 0,12099977 ! regulation of actin filament length GO:0030832 34 34 0,000 0,10785589 0,124392 ! response to metal ion GO:0010038 34 34 0,000 0,10785589 0,1243142 ! ear development GO:0043583 34 34 0,000 0,10785589 0,12423651 ! muscle cell differentiation GO:0042692 35 34 0,000 0,10785589 0,12415891 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,10785589 0,1240814 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,10785589 0,124004 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,10785589 0,12392669 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,10785589 0,12384948 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,10785589 0,12377236 ! secondary metabolic process GO:0019748 34 34 0,000 0,10785589 0,12369534 ! detection of stimulus GO:0051606 36 34 0,000 0,10785589 0,12361841 ! acute inflammatory response GO:0002526 35 35 0,000 0,11085316 0,12697475 ! regulation of cellular component size GO:0032535 35 35 0,000 0,11085316 0,12689589 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,11085316 0,12681712 ! mesoderm development GO:0007498 35 35 0,000 0,11085316 0,12673845 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,11085316 0,12665988 ! inorganic anion transport GO:0015698 35 35 0,000 0,11085316 0,1265814 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,11085316 0,12650302 ! regulation of immune effector process GO:0002697 35 35 0,000 0,11085316 0,12642474 ! hydrogen transport GO:0006818 36 36 0,000 0,1138408 0,12975176 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1138408 0,12967157 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1138408 0,12959147 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1138408 0,12951148 ! regulation of mitosis GO:0007088 37 36 0,000 0,1138408 0,12943158 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1138408 0,12935178 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,1138408 0,12927208 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1138408 0,12919248 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1138408 0,12911298 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1138408 0,12903358 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1138408 0,12895427 ! gonad development GO:0008406 36 36 0,000 0,1138408 0,12887506 ! activation of immune response GO:0002253 36 36 0,000 0,1138408 0,12879594 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,11681883 0,13208412 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,11681883 0,13200313 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,11681883 0,13192225 ! eye development GO:0001654 37 37 0,000 0,11681883 0,13184146 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,11681883 0,13176078 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,11681883 0,13168019 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,11681883 0,1315997 ! adaptive immune response GO:0002250 37 37 0,000 0,11681883 0,13151931 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,11978729 0,13477899 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,11978729 0,13469675 ! exocytosis GO:0006887 40 38 0,000 0,11978729 0,13461462 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,11978729 0,13453259 ! chromosome segregation GO:0007059 38 38 0,000 0,11978729 0,13445066 ! urogenital system development GO:0001655 38 38 0,000 0,11978729 0,13436883 ! hexose catabolic process GO:0019320 38 38 0,000 0,11978729 0,13428709 ! meiotic cell cycle GO:0051321 38 38 0,000 0,11978729 0,13420546 ! axon guidance GO:0007411 39 38 0,000 0,11978729 0,13412392 ! regulation of neurological system process GO:0031644 38 38 0,000 0,11978729 0,13404249 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,11978729 0,13396115 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,12274621 0,13718694 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,12274621 0,13710379 ! response to unfolded protein GO:0006986 39 39 0,000 0,12274621 0,13702075 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,12274621 0,13693781 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,12274621 0,13685497 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,12274621 0,13677222 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,12274621 0,13668958 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,12274621 0,13660704 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,12274621 0,1365246 ! developmental maturation GO:0021700 39 39 0,000 0,12274621 0,13644226 ! limb development GO:0060173 39 39 0,000 0,12274621 0,13636001 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,12569561 0,13955241 ! DNA catabolic process GO:0006308 41 40 0,000 0,12569561 0,13946839 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,12569561 0,13938448 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,12569561 0,13930066 ! organelle localization GO:0051640 41 40 0,000 0,12569561 0,13921695 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,12863552 0,14238754 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,12863552 0,14230208 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,12863552 0,14221671 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,12863552 0,14213145 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,12863552 0,14204629 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,12863552 0,14196123 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,12863552 0,14187628 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,13156597 0,14502158 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,13156597 0,1449349 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,13156597 0,14484832 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,13156597 0,14476184 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,13156597 0,14467547 ! protein ubiquitination GO:0016567 43 42 0,000 0,13156597 0,1445892 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,13156597 0,14450303 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,13156597 0,14441697 ! forebrain development GO:0030900 43 42 0,000 0,13156597 0,14433101 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,13156597 0,14424515 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,13156597 0,14415939 ! reproductive structure development GO:0048608 43 43 0,000 0,134487 0,14727245 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,134487 0,147185 ! alcohol catabolic process GO:0046164 43 43 0,000 0,134487 0,14709765 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,134487 0,1470104 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,134487 0,14692326 ! humoral immune response GO:0006959 44 44 0,000 0,13739863 0,15001521 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,13739863 0,14992639 ! mRNA transport GO:0051028 44 44 0,000 0,13739863 0,14983768 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,13739863 0,14974907 ! vitamin metabolic process GO:0006766 44 44 0,000 0,13739863 0,14966056 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,13739863 0,14957216 ! amine biosynthetic process GO:0009309 46 45 0,000 0,14030089 0,1526414 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,14030089 0,15255135 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,14030089 0,1524614 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,14030089 0,15237156 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,14030089 0,15228182 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,14030089 0,15219219 ! protein processing GO:0016485 45 45 0,000 0,14030089 0,15210267 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,1431938 0,15514766 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,1431938 0,15505651 ! tube morphogenesis GO:0035239 47 46 0,000 0,1431938 0,15496546 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,1431938 0,15487452 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,1431938 0,15478368 ! regulation of membrane potential GO:0042391 46 46 0,000 0,1431938 0,15469295 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,1460774 0,15771567 ! regulation of blood pressure GO:0008217 48 47 0,000 0,1460774 0,15762333 ! sex differentiation GO:0007548 47 47 0,000 0,1460774 0,1575311 ! amine transport GO:0015837 47 47 0,000 0,1460774 0,15743898 ! rhythmic process GO:0048511 47 47 0,000 0,1460774 0,15734696 ! calcium ion transport GO:0006816 48 48 0,000 0,14895172 0,16034931 ! actin filament organization GO:0007015 50 48 0,000 0,14895172 0,16025571 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,14895172 0,16016221 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,14895172 0,16006882 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,14895172 0,15997554 ! DNA recombination GO:0006310 48 48 0,000 0,14895172 0,15988237 ! gland development GO:0048732 51 49 0,000 0,15181679 0,16286283 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,15181679 0,16276808 ! divalent metal ion transport GO:0070838 49 49 0,000 0,15181679 0,16267345 ! response to nutrient GO:0007584 49 49 0,000 0,15181679 0,16257893 ! response to bacterium GO:0009617 50 49 0,000 0,15181679 0,16248452 ! regulation of ligase activity GO:0051340 50 49 0,000 0,15181679 0,16239021 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,15181679 0,16229602 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,15181679 0,16220193 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,15467262 0,16515738 ! chromatin assembly GO:0031497 50 50 0,000 0,15467262 0,16506175 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,15467262 0,16496623 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,15467262 0,16487082 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,15467262 0,16477552 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,15467262 0,16468032 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,15751926 0,16761432 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,15751926 0,1675176 ! positive regulation of immune response GO:0050778 51 51 0,000 0,15751926 0,16742099 ! rRNA metabolic process GO:0016072 51 51 0,000 0,15751926 0,16732449 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,15751926 0,16722811 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,15751926 0,16713183 ! protein maturation GO:0051604 51 51 0,000 0,15751926 0,16703567 ! RNA localization GO:0006403 52 52 0,000 0,16035672 0,16994678 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,16035672 0,16984911 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,16035672 0,16975155 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,16035672 0,1696541 ! sodium ion transport GO:0006814 53 53 0,000 0,16318505 0,17254736 ! tRNA metabolic process GO:0006399 53 53 0,000 0,16318505 0,17244842 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,16318505 0,1723496 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,16318505 0,17225088 ! regulation of T cell activation GO:0050863 53 53 0,000 0,16318505 0,17215229 ! response to virus GO:0009615 54 54 0,000 0,16600426 0,17502623 ! sulfur metabolic process GO:0006790 55 54 0,000 0,16600426 0,17492616 ! nucleosome organization GO:0034728 55 55 0,000 0,16881438 0,17778566 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,16881438 0,17768413 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,16881438 0,17758271 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,16881438 0,17748141 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,17161545 0,18032341 ! extracellular structure organization GO:0043062 56 56 0,000 0,17161545 0,18022067 ! ATP metabolic process GO:0046034 57 57 0,000 0,17440748 0,1830484 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,17440748 0,18294422 ! innate immune response GO:0045087 58 58 0,000 0,17719051 0,18575775 ! carboxylic acid transport GO:0046942 59 59 0,000 0,17996457 0,18855867 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,17996457 0,18845154 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,17996457 0,18834452 ! immune effector process GO:0002252 59 59 0,000 0,17996457 0,18823763 ! potassium ion transport GO:0006813 60 60 0,000 0,18272968 0,19102144 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,18272968 0,19091315 ! protein polymerization GO:0051258 65 60 0,000 0,18272968 0,19080499 ! cellular respiration GO:0045333 62 61 0,000 0,18548587 0,19357331 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,18548587 0,19346376 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,18548587 0,19335433 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,18548587 0,19324503 ! lipid transport GO:0006869 62 62 0,000 0,18823317 0,19599646 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,18823317 0,19588579 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,18823317 0,19577524 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,18823317 0,19566482 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,18823317 0,19555453 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,18823317 0,19544436 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,1909716 0,19817605 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,1909716 0,19806453 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,1909716 0,19795313 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,1937012 0,20066965 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,1937012 0,20055691 ! anion transport GO:0006820 65 65 0,000 0,19642198 0,20325981 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,19642198 0,20314574 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,19913399 0,20583507 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,19913399 0,20571969 ! DNA packaging GO:0006323 66 66 0,000 0,19913399 0,20560445 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,19913399 0,20548932 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,19913399 0,20537433 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,20183723 0,20804587 ! muscle contraction GO:0006936 67 67 0,000 0,20183723 0,20792958 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,20183723 0,20781342 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,20453175 0,21047013 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,20453175 0,21035268 ! regulation of translation GO:0006417 69 69 0,000 0,20721756 0,21299608 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,20721756 0,21287735 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,2098947 0,21550749 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,21256319 0,21812582 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,21256319 0,21800443 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,21256319 0,21788318 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,21256319 0,21776207 ! regulation of cell activation GO:0050865 71 71 0,000 0,21256319 0,21764109 ! secretion by cell GO:0032940 75 72 0,000 0,21522306 0,22024214 ! muscle system process GO:0003012 72 72 0,000 0,21522306 0,22011992 ! sensory organ development GO:0007423 72 72 0,000 0,21522306 0,21999784 ! regulation of cytokine production GO:0001817 72 72 0,000 0,21522306 0,21987589 ! electron transport chain GO:0022900 75 74 0,000 0,22051704 0,2251595 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,22051704 0,22503483 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,2231512 0,22759694 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,2231512 0,22747105 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,22577685 0,2300203 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,22577685 0,22989322 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,228394 0,23242968 ! microtubule-based movement GO:0007018 82 78 0,000 0,2310027 0,23495473 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,2310027 0,23482514 ! metal ion homeostasis GO:0055065 78 78 0,000 0,2310027 0,23469568 ! regulation of immune response GO:0050776 78 78 0,000 0,2310027 0,23456638 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,2361948 0,2397065 ! lipid catabolic process GO:0016042 82 81 0,000 0,23877826 0,24219501 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,24392012 0,24727436 ! ncRNA processing GO:0034470 83 83 0,000 0,24392012 0,24713842 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,24647858 0,24959342 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,24902875 0,25203734 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,24902875 0,25189901 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,25157067 0,25433064 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,25662984 0,25930307 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,25662984 0,25916099 ! chemotaxis GO:0006935 90 89 0,000 0,25914714 0,2615598 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,25914714 0,26141663 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,26165629 0,26380336 ! brain development GO:0007420 91 90 0,000 0,26165629 0,26365913 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,26415731 0,26603384 ! visual perception GO:0007601 93 92 0,000 0,26665022 0,26839779 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,26665022 0,26825129 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,26665022 0,26810494 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,26665022 0,26795875 ! tissue morphogenesis GO:0048729 94 93 0,000 0,26913505 0,27030839 ! cofactor metabolic process GO:0051186 95 94 0,000 0,27161183 0,27264739 ! endocytosis GO:0006897 99 98 0,000 0,2814389 0,28235813 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,2814389 0,28220451 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,2814389 0,28205105 ! blood circulation GO:0008015 99 98 0,000 0,2814389 0,28189776 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,2814389 0,28174464 ! anti-apoptosis GO:0006916 100 99 0,000 0,28387577 0,28402989 ! response to other organism GO:0051707 101 100 0,000 0,28630475 0,28630475