pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6130-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of peptide secretion GO:0002792 6 5 3,000 4,055E-10 9,327E-07 GO:0046676|negative regulation of insulin secretion, ! regulation of protein export from nucleus GO:0046825 6 6 3,000 1,214E-09 1,396E-06 ! organ growth GO:0035265 11 7 3,000 2,826E-09 2,166E-06 ! regulation of growth hormone secretion GO:0060123 11 7 3,000 2,826E-09 1,625E-06 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 3,000 5,638E-09 2,594E-06 ! DNA damage checkpoint GO:0000077 53 31 4,000 3,718E-08 1,425E-05 ! carbohydrate homeostasis GO:0033500 39 33 4,000 5,169E-08 1,698E-05 GO:0042593|glucose homeostasis, ! DNA integrity checkpoint GO:0031570 57 34 4,000 6,046E-08 1,738E-05 ! regulation of intracellular protein transport GO:0033157 59 35 4,000 7,038E-08 1,799E-05 ! negative regulation of hormone secretion GO:0046888 20 15 3,000 1,082E-07 2,489E-05 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 4,000 1,814E-07 3,793E-05 ! positive regulation of hormone secretion GO:0046887 24 17 3,000 1,878E-07 3,599E-05 ! positive regulation of MAP kinase activity GO:0043406 121 85 5,000 2,367E-07 4,188E-05 ! regulation of intracellular transport GO:0032386 78 49 4,000 4,001E-07 6,573E-05 ! regulation of insulin secretion GO:0050796 26 21 3,000 4,679E-07 7,175E-05 ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 5,706E-07 8,202E-05 ! DNA damage response, signal transduction GO:0042770 96 56 4,000 7,884E-07 1,067E-04 ! regulation of peptide secretion GO:0002791 34 25 3,000 9,8E-07 1,252E-04 ! activation of MAPK activity GO:0000187 84 59 4,000 1,026E-06 1,242E-04 ! cell cycle checkpoint GO:0000075 108 64 4,000 1,545E-06 1,776E-04 ! triglyceride metabolic process GO:0006641 34 28 3,000 1,575E-06 1,725E-04 ! negative regulation of secretion GO:0051048 49 31 3,000 2,404E-06 2,514E-04 ! neutral lipid metabolic process GO:0006638 41 32 3,000 2,742E-06 2,742E-04 GO:0006639|acylglycerol metabolic process, ! cellular response to hormone stimulus GO:0032870 109 74 4,000 3,188E-06 3,055E-04 ! glycerol ether metabolic process GO:0006662 44 34 3,000 3,52E-06 3,238E-04 ! regulation of protein transport GO:0051223 114 76 4,000 3,639E-06 3,219E-04 GO:0070201|regulation of establishment of protein localization, ! regulation of hormone secretion GO:0046883 48 36 3,000 4,45E-06 3,791E-04 ! organic ether metabolic process GO:0018904 46 36 3,000 4,45E-06 3,655E-04 ! hormone-mediated signaling GO:0009755 49 36 3,000 4,45E-06 3,529E-04 ! regulation of protein localization GO:0032880 132 85 4,000 6,327E-06 4,851E-04 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 1,103E-05 8,181E-04 ! response to UV GO:0009411 75 46 3,000 1,205E-05 8,66E-04 ! positive regulation of neuron apoptosis GO:0043525 29 15 2,000 1,235E-05 8,606E-04 ! regulation of multicellular organism growth GO:0040014 65 50 3,000 1,685E-05 1,14E-03 ! positive regulation of secretion GO:0051047 71 51 3,000 1,824E-05 1,199E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,824E-05 1,165E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,837E-05 1,142E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 2,607E-05 1,578E-03 ! multicellular organism reproduction GO:0032504 83 57 3,000 2,844E-05 1,677E-03 GO:0048609|reproductive process in a multicellular organism, ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 3,06E-05 1,759E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 3,562E-05 1,998E-03 ! protein tetramerization GO:0051262 39 22 2,000 4,116E-05 2,254E-03 ! regulation of caspase activity GO:0043281 97 65 3,000 4,787E-05 2,56E-03 ! protein oligomerization GO:0051259 100 65 3,000 4,787E-05 2,502E-03 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 5,394E-05 2,757E-03 ! regulation of peptidase activity GO:0052547 106 72 3,000 7,158E-05 3,579E-03 ! negative regulation of transport GO:0051051 116 73 3,000 7,556E-05 3,698E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 9,309E-05 4,461E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 9,309E-05 4,37E-03 ! microvillus organization GO:0032528 7 5 1,000 9,309E-05 4,282E-03 GO:0030033|microvillus assembly, ! regulation of respiratory burst GO:0060263 8 5 1,000 9,309E-05 4,198E-03 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 9,309E-05 4,118E-03 ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 1,297E-04 5,628E-03 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 1,368E-04 5,825E-03 ! regulation of helicase activity GO:0051095 11 6 1,000 1,394E-04 5,828E-03 ! neuron adhesion GO:0007158 9 6 1,000 1,394E-04 5,724E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,394E-04 5,624E-03 ! activation of MAPKKK activity GO:0000185 10 6 1,000 1,394E-04 5,527E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,394E-04 5,433E-03 ! ER overload response GO:0006983 7 6 1,000 1,394E-04 5,342E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 1,394E-04 5,255E-03 ! male sex determination GO:0030238 9 6 1,000 1,394E-04 5,17E-03 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 1,394E-04 5,088E-03 ! axonal fasciculation GO:0007413 9 6 1,000 1,394E-04 5,008E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 1,431E-04 5,064E-03 ! interphase GO:0051325 159 88 3,000 1,564E-04 5,451E-03 ! hormone metabolic process GO:0042445 121 90 3,000 1,706E-04 5,857E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,947E-04 6,586E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 1,947E-04 6,491E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 1,947E-04 6,398E-03 ! B cell lineage commitment GO:0002326 17 7 1,000 1,947E-04 6,308E-03 ! T cell lineage commitment GO:0002360 12 7 1,000 1,947E-04 6,22E-03 ! response to tumor cell GO:0002347 12 7 1,000 1,947E-04 6,135E-03 ! response to light stimulus GO:0009416 153 96 3,000 2,188E-04 6,801E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 2,353E-04 7,217E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 2,539E-04 7,683E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 2,591E-04 7,74E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 2,591E-04 7,641E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 2,591E-04 7,544E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 3,15E-04 9,057E-03 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 3,15E-04 8,945E-03 ! activation of caspase activity GO:0006919 65 43 2,000 3,15E-04 8,836E-03 ! regulation of developmental growth GO:0048638 13 9 1,000 3,325E-04 9,214E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 3,325E-04 9,104E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 3,325E-04 8,997E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 1,000 3,325E-04 8,892E-03 ! localization within membrane GO:0051668 15 9 1,000 3,325E-04 8,79E-03 ! regulation of neuron apoptosis GO:0043523 77 47 2,000 4,103E-04 0,01072421 ! regulation of B cell proliferation GO:0030888 15 10 1,000 4,148E-04 0,0107194 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 4,148E-04 0,01060029 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 4,148E-04 0,0104838 ! response to X-ray GO:0010165 16 10 1,000 4,148E-04 0,01036985 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 4,148E-04 0,01025835 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 4,148E-04 0,01014922 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of caspase activity GO:0043280 72 48 2,000 4,367E-04 0,01057319 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 2,000 4,367E-04 0,01046305 ! virus-host interaction GO:0019048 17 11 1,000 5,06E-04 0,01199715 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 5,06E-04 0,01187473 ! focal adhesion formation GO:0048041 24 11 1,000 5,06E-04 0,01175478 ! regulation of intracellular pH GO:0051453 17 11 1,000 5,06E-04 0,01163723 ! nitric oxide metabolic process GO:0046209 14 11 1,000 5,06E-04 0,01152201 GO:0006809|nitric oxide biosynthetic process, ! positive regulation of cell migration GO:0030335 92 51 2,000 5,224E-04 0,01177953 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 6,06E-04 0,0135311 ! histone acetylation GO:0016573 23 12 1,000 6,06E-04 0,013401 ! peptidyl-lysine modification GO:0018205 18 12 1,000 6,06E-04 0,01327337 ! response to gamma radiation GO:0010332 20 12 1,000 6,06E-04 0,01314815 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 6,06E-04 0,01302527 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of cell motion GO:0051272 99 56 2,000 6,878E-04 0,01464806 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 7,147E-04 0,01508114 ! regulation of DNA repair GO:0006282 15 13 1,000 7,147E-04 0,01494404 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 7,147E-04 0,01480941 ! regulation of cellular pH GO:0030641 20 13 1,000 7,147E-04 0,01467718 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 7,147E-04 0,0145473 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 7,245E-04 0,01461618 ! negative regulation of kinase activity GO:0033673 100 58 2,000 7,623E-04 0,01524614 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 8,322E-04 0,0165002 ! activation of MAPKK activity GO:0000186 21 14 1,000 8,322E-04 0,01635918 ! cellular response to starvation GO:0009267 21 14 1,000 8,322E-04 0,01622054 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 8,322E-04 0,01608423 ! G1/S transition checkpoint GO:0031575 33 14 1,000 8,322E-04 0,0159502 ! synaptic transmission, cholinergic GO:0007271 21 14 1,000 8,322E-04 0,01581838 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 8,322E-04 0,01568872 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 8,322E-04 0,01556117 ! negative regulation of transferase activity GO:0051348 105 61 2,000 8,834E-04 0,01638478 ! negative regulation of cell growth GO:0030308 106 62 2,000 9,263E-04 0,01704301 ! neuron recognition GO:0008038 22 15 1,000 9,583E-04 0,01749302 ! regulation of transcription factor activity GO:0051090 97 63 2,000 9,704E-04 0,01757504 GO:0090046|regulation of transcription regulator activity, ! negative regulation of cell size GO:0045792 108 64 2,000 1,016E-03 0,01825554 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,093E-03 0,01948846 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,093E-03 0,01933855 ! G1 phase GO:0051318 27 16 1,000 1,093E-03 0,01919093 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,093E-03 0,01904554 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 1,236E-03 0,02138029 ! cell-substrate junction assembly GO:0007044 39 17 1,000 1,236E-03 0,02122074 ! actin filament bundle formation GO:0051017 26 17 1,000 1,236E-03 0,02106355 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,388E-03 0,02347575 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,388E-03 0,02330439 ! somitogenesis GO:0001756 24 18 1,000 1,388E-03 0,02313552 ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,388E-03 0,02296908 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 1,388E-03 0,02280501 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,548E-03 0,02525717 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 1,548E-03 0,0250793 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 1,548E-03 0,02490392 ! response to starvation GO:0042594 30 19 1,000 1,548E-03 0,02473098 ! sex determination GO:0007530 29 19 1,000 1,548E-03 0,02456042 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 1,548E-03 0,0243922 ! negative regulation of growth GO:0045926 123 75 2,000 1,608E-03 0,02515341 ! positive regulation of B cell activation GO:0050871 31 20 1,000 1,717E-03 0,02668335 ! regulation of DNA binding GO:0051101 119 77 2,000 1,734E-03 0,02676636 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 1,894E-03 0,0290414 ! gluconeogenesis GO:0006094 25 21 1,000 1,894E-03 0,02884908 ! protein amino acid acylation GO:0043543 37 21 1,000 1,894E-03 0,02865928 ! cell aging GO:0007569 32 21 1,000 1,894E-03 0,02847196 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 1,894E-03 0,02828708 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 1,894E-03 0,02810458 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 2,079E-03 0,03065619 ! glutamate signaling pathway GO:0007215 34 22 1,000 2,079E-03 0,03046093 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 2,079E-03 0,03026814 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 2,079E-03 0,03007777 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 2,273E-03 0,03267178 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 2,273E-03 0,03246885 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 2,273E-03 0,03226842 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,273E-03 0,03207046 ! negative regulation of DNA replication GO:0008156 35 23 1,000 2,273E-03 0,0318749 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,273E-03 0,03168172 ! interaction with host GO:0051701 37 23 1,000 2,273E-03 0,03149087 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 2,273E-03 0,0313023 ! cell cycle arrest GO:0007050 150 86 2,000 2,379E-03 0,03256899 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,475E-03 0,03367722 ! pyruvate metabolic process GO:0006090 29 24 1,000 2,475E-03 0,03347911 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 2,475E-03 0,03328333 ! mitochondrial membrane organization GO:0007006 39 24 1,000 2,475E-03 0,03308982 ! response to toxin GO:0009636 38 24 1,000 2,475E-03 0,03289855 ! negative regulation of cell development GO:0010721 56 24 1,000 2,475E-03 0,03270948 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 2,475E-03 0,03252257 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 2,475E-03 0,03233778 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 2,475E-03 0,03215508 ! regulation of neurogenesis GO:0050767 153 89 2,000 2,623E-03 0,03388907 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 2,684E-03 0,03449243 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,684E-03 0,03430081 ! translational initiation GO:0006413 43 26 1,000 2,902E-03 0,03688097 ! regulation of pH GO:0006885 36 26 1,000 2,902E-03 0,03667833 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 2,902E-03 0,0364779 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 2,971E-03 0,03713739 ! response to ionizing radiation GO:0010212 47 27 1,000 3,128E-03 0,03889332 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 3,128E-03 0,03868422 GO:0043433|negative regulation of transcription factor activity, ! regulation of binding GO:0051098 151 95 2,000 3,155E-03 0,03880834 ! cell junction assembly GO:0034329 56 28 1,000 3,362E-03 0,04113542 ! positive regulation of catabolic process GO:0009896 40 28 1,000 3,362E-03 0,04091777 ! regulation of B cell activation GO:0050864 42 28 1,000 3,362E-03 0,04070242 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 3,604E-03 0,04340274 ! hexose biosynthetic process GO:0019319 35 29 1,000 3,604E-03 0,04317668 ! xenobiotic metabolic process GO:0006805 44 31 1,000 4,112E-03 0,04900108 ! segmentation GO:0035282 41 31 1,000 4,112E-03 0,0487485 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 4,112E-03 0,04849851 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 4,377E-03 0,05136634 ! calcium-mediated signaling GO:0019722 50 32 1,000 4,377E-03 0,0511056 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 4,377E-03 0,05084749 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 4,377E-03 0,05059198 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4,651E-03 0,05348108 ! cell junction organization GO:0034330 63 33 1,000 4,651E-03 0,05321501 ! negative regulation of DNA binding GO:0043392 54 33 1,000 4,651E-03 0,05295157 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 4,651E-03 0,05269072 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 4,931E-03 0,05559969 ! neuron migration GO:0001764 46 34 1,000 4,931E-03 0,05532847 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 4,931E-03 0,05505989 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 5,22E-03 0,05800025 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 5,22E-03 0,0577214 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 5,516E-03 0,06070456 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 5,516E-03 0,06041549 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 5,516E-03 0,06012916 ! gliogenesis GO:0042063 71 38 1,000 6,131E-03 0,06651729 ! alcohol biosynthetic process GO:0046165 45 38 1,000 6,131E-03 0,066205 ! cell growth GO:0016049 61 39 1,000 6,45E-03 0,06932084 ! T cell differentiation GO:0030217 65 40 1,000 6,776E-03 0,07248698 ! double-strand break repair GO:0006302 67 40 1,000 6,776E-03 0,0721514 ! B cell differentiation GO:0030183 62 40 1,000 6,776E-03 0,0718189 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 6,776E-03 0,07148946 ! positive regulation of protein transport GO:0051222 55 40 1,000 6,776E-03 0,07116302 ! positive regulation of DNA binding GO:0043388 57 41 1,000 7,109E-03 0,07432582 ! mitochondrial transport GO:0006839 60 42 1,000 7,45E-03 0,07753616 ! positive regulation of binding GO:0051099 59 43 1,000 7,798E-03 0,08079291 ! response to insulin stimulus GO:0032868 63 43 1,000 7,798E-03 0,08043061 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 8,154E-03 0,08371953 ! positive regulation of cell cycle GO:0045787 77 45 1,000 8,516E-03 0,0870526 ! cell recognition GO:0008037 58 45 1,000 8,516E-03 0,08666741 ! regulation of ossification GO:0030278 71 46 1,000 8,886E-03 0,09003039 ! histone modification GO:0016570 68 46 1,000 8,886E-03 0,08963552 ! covalent chromatin modification GO:0016569 75 47 1,000 9,262E-03 0,09302735 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 9,262E-03 0,09262288 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 9,262E-03 0,09222192 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! heart morphogenesis GO:0003007 65 48 1,000 9,646E-03 0,09562853 ! RNA elongation GO:0006354 62 49 1,000 0,01003672 0,09907496 ! positive regulation of growth GO:0045927 67 50 1,000 0,01043439 0,10256025 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01083896 0,10608345 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cell motion GO:0051271 104 51 1,000 0,01083896 0,10563395 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01125039 0,10918103 ! aging GO:0007568 79 52 1,000 0,01125039 0,10872228 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,01125039 0,10826738 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01166864 0,11182447 ! cell projection assembly GO:0030031 76 53 1,000 0,01166864 0,11136047 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01209366 0,11493973 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,01209366 0,11446673 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01209366 0,1139976 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,01296383 0,1217013 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,0134089 0,12536778 ! viral reproductive process GO:0022415 87 58 1,000 0,01386057 0,129066 ! lung development GO:0030324 94 59 1,000 0,01431878 0,13279516 ! actin filament organization GO:0007015 95 59 1,000 0,01431878 0,13226185 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01478351 0,13600828 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,0152547 0,1397841 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,0152547 0,1392294 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01535108 0,13955531 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01535108 0,13900588 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01535108 0,13846076 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01535108 0,1379199 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01535108 0,13738325 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01535108 0,13685075 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01535108 0,13632237 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01535108 0,13579805 ! sleep GO:0030431 11 5 0,000 0,01535108 0,13527776 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01535108 0,13476143 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01535108 0,13424903 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01535108 0,13374051 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01535108 0,13323583 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01535108 0,13273494 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01535108 0,13223781 ! tongue development GO:0043586 6 5 0,000 0,01535108 0,13174438 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01535108 0,13125462 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01535108 0,1307685 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01535108 0,13028596 ! cobalt ion transport GO:0006824 9 5 0,000 0,01535108 0,12980696 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01535108 0,12933148 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01535108 0,12885947 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01535108 0,12839089 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01535108 0,1279257 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01535108 0,12746388 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01535108 0,12700537 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01535108 0,12655016 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01535108 0,12609819 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01535108 0,12564945 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01535108 0,12520388 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01535108 0,12476146 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01535108 0,12432216 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01535108 0,12388594 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01535108 0,12345278 ! malate metabolic process GO:0006108 7 5 0,000 0,01535108 0,12302263 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01535108 0,12259547 ! behavioral response to pain GO:0048266 7 5 0,000 0,01535108 0,12217126 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01535108 0,12174998 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01535108 0,12133159 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01535108 0,12091608 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01535108 0,12050339 ! mating behavior GO:0007617 6 5 0,000 0,01535108 0,12009352 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01535108 0,11968642 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01535108 0,11928207 ! rhythmic behavior GO:0007622 12 5 0,000 0,01535108 0,11888045 ! copulation GO:0007620 7 5 0,000 0,01535108 0,11848152 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01535108 0,11808526 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01535108 0,11769165 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01535108 0,11730064 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01535108 0,11691223 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01535108 0,11652638 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01535108 0,11614307 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01535108 0,11576228 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01535108 0,11538397 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01535108 0,11500812 ! response to protozoan GO:0001562 9 5 0,000 0,01535108 0,11463472 ! lymph vessel development GO:0001945 7 5 0,000 0,01535108 0,11426373 ! endochondral ossification GO:0001958 12 5 0,000 0,01535108 0,11389514 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01535108 0,11352892 ! parathyroid gland development GO:0060017 8 5 0,000 0,01535108 0,11316505 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01535108 0,1128035 ! anagen GO:0042640 6 5 0,000 0,01535108 0,11244425 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01535108 0,11208728 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01535108 0,11173258 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01535108 0,11138011 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01535108 0,11102986 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01535108 0,1106818 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01535108 0,11033592 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01535108 0,10999219 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01535108 0,1096506 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01535108 0,10931113 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01535108 0,10897375 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01535108 0,10863844 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01535108 0,1083052 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01535108 0,10797399 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01535108 0,1076448 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01535108 0,10731761 ! ovulation GO:0030728 6 5 0,000 0,01535108 0,10699241 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01535108 0,10666917 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,01535108 0,10634787 ! response to pH GO:0009268 9 5 0,000 0,01535108 0,10602851 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01535108 0,10571106 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01535108 0,1053955 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01535108 0,10508183 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01535108 0,10477001 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01535108 0,10446004 ! polyol catabolic process GO:0046174 7 5 0,000 0,01535108 0,1041519 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01535108 0,10384557 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01535108 0,10354104 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01535108 0,10323829 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01535108 0,1029373 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01535108 0,10263806 ! urea metabolic process GO:0019627 6 5 0,000 0,01535108 0,10234056 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01535108 0,10204478 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01535108 0,1017507 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01535108 0,10145832 ! neutrophil activation GO:0042119 5 5 0,000 0,01535108 0,1011676 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01535108 0,10087855 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01535108 0,10059115 ! response to food GO:0032094 5 5 0,000 0,01535108 0,10030538 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01535108 0,10002123 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01535108 0,09973868 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01535108 0,09945773 ! forebrain neuron development GO:0021884 7 5 0,000 0,01535108 0,09917835 ! melanosome organization GO:0032438 7 5 0,000 0,01535108 0,09890054 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01535108 0,09862429 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01535108 0,09834957 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01535108 0,09807637 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01535108 0,09780469 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01535108 0,09753451 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01535108 0,09726582 ! nucleoside transport GO:0015858 6 5 0,000 0,01535108 0,09699861 ! nucleoside salvage GO:0043174 7 5 0,000 0,01535108 0,09673286 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01535108 0,09646856 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01535108 0,09620571 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01535108 0,09594428 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01535108 0,09568427 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01535108 0,09542566 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01535108 0,09516845 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01535108 0,09491262 ! depyrimidination GO:0045008 8 5 0,000 0,01535108 0,09465816 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01535108 0,09440506 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01535108 0,09415332 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01535108 0,09390291 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01535108 0,09365383 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01535108 0,09340607 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01535108 0,09315961 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01535108 0,09291446 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01535108 0,09267059 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01535108 0,09242799 ! monocyte differentiation GO:0030224 8 5 0,000 0,01535108 0,09218667 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01535108 0,0919466 ! centrosome duplication GO:0051298 5 5 0,000 0,01535108 0,09170778 ! response to UV-C GO:0010225 6 5 0,000 0,01535108 0,09147019 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01535108 0,09123383 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01535108 0,0909987 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01535108 0,09076477 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01535108 0,09053204 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01535108 0,0903005 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01535108 0,09007014 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01535108 0,08984095 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01535108 0,08961293 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01535108 0,08938606 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01535108 0,08916034 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01535108 0,08893575 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01535108 0,0887123 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01535108 0,08848996 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01535108 0,08826874 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01535108 0,08804861 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01535108 0,08782959 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01535108 0,08761165 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01535108 0,08739479 ! neural tube patterning GO:0021532 6 5 0,000 0,01535108 0,087179 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01535108 0,08696427 ! histone demethylation GO:0016577 9 5 0,000 0,01535108 0,0867506 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01535108 0,08653798 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01535108 0,08632639 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01535108 0,08611584 ! enteric nervous system development GO:0048484 8 5 0,000 0,01535108 0,08590631 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01535108 0,0856978 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01535108 0,0854903 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01535108 0,0852838 ! transcription termination GO:0006353 8 5 0,000 0,01535108 0,0850783 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01535108 0,08487378 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01535108 0,08467025 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01535108 0,08446769 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01535108 0,0842661 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01535108 0,08406546 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01535108 0,08386578 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01535108 0,08366705 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01535108 0,08346925 ! apical protein localization GO:0045176 6 5 0,000 0,01535108 0,08327239 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01535108 0,08307646 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01535108 0,08288144 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01535108 0,08268734 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01535108 0,08249415 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01535108 0,08230185 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01535108 0,08211045 ! glial cell migration GO:0008347 10 5 0,000 0,01535108 0,08191994 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01535108 0,08173031 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01535108 0,08154156 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01535108 0,08135367 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01535108 0,08116665 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01535108 0,08098049 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01535108 0,08079518 ! neural plate development GO:0001840 6 5 0,000 0,01535108 0,08061072 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01535108 0,08042709 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01535108 0,0802443 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01535108 0,08006234 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01535108 0,07988121 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01535108 0,07970089 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01535108 0,07952138 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01535108 0,07934268 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01535108 0,07916478 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01535108 0,07898768 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01535108 0,07881137 ! spindle assembly GO:0051225 5 5 0,000 0,01535108 0,07863584 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01535108 0,0784611 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01535108 0,07828713 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01535108 0,07811392 ! organ regeneration GO:0031100 7 5 0,000 0,01535108 0,07794149 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01535108 0,07776981 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01535108 0,07759889 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01535108 0,07742872 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01535108 0,07725929 GO:0055081|anion homeostasis, ! respiratory tube development GO:0030323 99 62 1,000 0,01573231 0,07900508 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,01621631 0,0812582 ! viral reproduction GO:0016032 92 63 1,000 0,01621631 0,08108155 ! regulation of lipase activity GO:0060191 109 63 1,000 0,01621631 0,08090567 ! respiratory system development GO:0060541 100 64 1,000 0,01670664 0,08317161 ! B cell activation GO:0042113 104 65 1,000 0,01720327 0,08545903 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,01770616 0,08776759 ! axon guidance GO:0007411 99 66 1,000 0,01770616 0,08757885 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,01821525 0,08990361 ! tRNA transcription GO:0009304 11 6 0,000 0,01839343 0,09058862 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01839343 0,09039505 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01839343 0,09020231 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01839343 0,09001039 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01839343 0,08981929 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01839343 0,08962899 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01839343 0,0894395 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01839343 0,08925081 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01839343 0,08906292 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01839343 0,08887581 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01839343 0,08868949 ! prostate gland development GO:0030850 9 6 0,000 0,01839343 0,08850394 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01839343 0,08831917 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01839343 0,08813518 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01839343 0,08795194 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01839343 0,08776947 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01839343 0,08758775 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01839343 0,08740679 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01839343 0,08722657 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01839343 0,08704709 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01839343 0,08686835 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01839343 0,08669034 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01839343 0,08651306 ! signal peptide processing GO:0006465 8 6 0,000 0,01839343 0,0863365 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01839343 0,08616066 ! mRNA stabilization GO:0048255 15 6 0,000 0,01839343 0,08598554 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01839343 0,08581113 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01839343 0,08563742 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01839343 0,08546441 ! opsonization GO:0008228 8 6 0,000 0,01839343 0,08529211 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01839343 0,08512049 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01839343 0,08494957 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01839343 0,08477933 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01839343 0,08460977 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01839343 0,08444089 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01839343 0,08427268 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01839343 0,08410514 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01839343 0,08393826 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01839343 0,08377205 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01839343 0,08360649 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01839343 0,08344159 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01839343 0,08327733 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01839343 0,08311372 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01839343 0,08295075 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01839343 0,08278842 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01839343 0,08262673 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01839343 0,08246566 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01839343 0,08230522 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01839343 0,08214541 ! thymic T cell selection GO:0045061 12 6 0,000 0,01839343 0,08198621 ! protein lipoylation GO:0009249 10 6 0,000 0,01839343 0,08182763 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01839343 0,08166966 ! pigment granule organization GO:0048753 11 6 0,000 0,01839343 0,0815123 ! drug transport GO:0015893 6 6 0,000 0,01839343 0,08135555 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01839343 0,08119939 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01839343 0,08104384 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01839343 0,08088888 ! histidine metabolic process GO:0006547 6 6 0,000 0,01839343 0,08073451 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01839343 0,08058073 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01839343 0,08042754 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01839343 0,08027492 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01839343 0,08012289 ! adenohypophysis development GO:0021984 10 6 0,000 0,01839343 0,07997143 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01839343 0,07982054 ! hyperosmotic response GO:0006972 8 6 0,000 0,01839343 0,07967022 ! microtubule nucleation GO:0007020 10 6 0,000 0,01839343 0,07952046 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01839343 0,07937127 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01839343 0,07922263 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01839343 0,07907455 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01839343 0,07892702 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01839343 0,07878005 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,01839343 0,07863361 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01839343 0,07848773 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01839343 0,07834238 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01839343 0,07819757 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01839343 0,07805329 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01839343 0,07790955 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01839343 0,07776633 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01839343 0,07762364 ! neuron apoptosis GO:0051402 8 6 0,000 0,01839343 0,07748147 ! organic alcohol transport GO:0015850 9 6 0,000 0,01839343 0,07733983 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01839343 0,07719869 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01839343 0,07705808 ! carnitine transport GO:0015879 8 6 0,000 0,01839343 0,07691797 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01839343 0,07677838 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01839343 0,07663928 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01839343 0,0765007 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01839343 0,07636261 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01839343 0,07622502 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01839343 0,07608792 ! parturition GO:0007567 12 6 0,000 0,01839343 0,07595132 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01839343 0,07581521 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01839343 0,07567958 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01839343 0,07554444 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01839343 0,07540978 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01839343 0,0752756 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01839343 0,07514189 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01839343 0,07500866 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01839343 0,0748759 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01839343 0,07474361 ! macrophage differentiation GO:0030225 10 6 0,000 0,01839343 0,07461179 ! astrocyte development GO:0014002 14 6 0,000 0,01839343 0,07448043 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01839343 0,07434953 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01839343 0,0742191 ! interaction with symbiont GO:0051702 8 6 0,000 0,01839343 0,07408912 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01839343 0,07395959 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01839343 0,07383051 ! eating behavior GO:0042755 6 6 0,000 0,01839343 0,07370189 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01839343 0,07357371 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01839343 0,07344598 ! response to copper ion GO:0046688 9 6 0,000 0,01839343 0,07331869 ! DNA topological change GO:0006265 8 6 0,000 0,01839343 0,07319184 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01839343 0,07306543 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01839343 0,07293946 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01839343 0,07281392 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01839343 0,07268881 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01839343 0,07256412 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01839343 0,07243987 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01839343 0,07231604 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01839343 0,07219264 ! gas homeostasis GO:0033483 11 6 0,000 0,01839343 0,07206965 ! hair follicle maturation GO:0048820 7 6 0,000 0,01839343 0,07194708 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01839343 0,07182493 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01839343 0,07170319 ! Schwann cell development GO:0014044 14 6 0,000 0,01839343 0,07158187 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01839343 0,07146095 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01839343 0,07134045 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01839343 0,07122034 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01839343 0,07110065 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01839343 0,07098135 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01839343 0,07086245 ! histone ubiquitination GO:0016574 7 6 0,000 0,01839343 0,07074395 ! regulation of meiosis GO:0040020 10 6 0,000 0,01839343 0,07062585 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01839343 0,07050814 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01839343 0,07039082 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01839343 0,07027389 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01839343 0,07015735 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01839343 0,0700412 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01839343 0,06992543 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01839343 0,06981004 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01839343 0,06969503 ! receptor internalization GO:0031623 9 6 0,000 0,01839343 0,0695804 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01839343 0,06946615 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01839343 0,06935227 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01839343 0,06923876 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01839343 0,06912563 ! protein deubiquitination GO:0016579 8 6 0,000 0,01839343 0,06901286 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01839343 0,06890046 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01839343 0,06878843 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01839343 0,06867676 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01839343 0,06856545 ! midbrain development GO:0030901 6 6 0,000 0,01839343 0,06845451 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01839343 0,06834392 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01839343 0,06823368 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01839343 0,06812381 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01839343 0,06801428 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01839343 0,06790511 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01839343 0,06779629 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01839343 0,06768782 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01839343 0,06757969 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01839343 0,06747191 ! adult feeding behavior GO:0008343 6 6 0,000 0,01839343 0,06736447 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01839343 0,06725737 ! blastocyst growth GO:0001832 15 6 0,000 0,01839343 0,06715061 ! pigment granule transport GO:0051904 12 6 0,000 0,01839343 0,06704419 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01839343 0,06693811 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01839343 0,06683236 ! catecholamine transport GO:0051937 7 6 0,000 0,01839343 0,06672695 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01839343 0,06662187 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01839343 0,06651711 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01839343 0,06641269 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01839343 0,0663086 ! protein prenylation GO:0018342 10 6 0,000 0,01839343 0,06620483 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01839343 0,06610138 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01839343 0,06599826 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01839343 0,06589546 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01839343 0,06579298 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01839343 0,06569081 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,01925192 0,06865024 ! response to drug GO:0042493 108 69 1,000 0,01925192 0,06854397 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,0197794 0,07031316 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,0197794 0,07020466 ! regulation of catabolic process GO:0009894 106 70 1,000 0,0197794 0,07009648 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,02031293 0,07187651 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,02085246 0,0736723 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,02085246 0,0735593 ! mitochondrion organization GO:0007005 104 73 1,000 0,02139796 0,07536802 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02142655 0,07535329 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02142655 0,07523825 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02142655 0,07512356 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02142655 0,07500921 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02142655 0,07489522 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02142655 0,07478157 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02142655 0,07466826 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02142655 0,0745553 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02142655 0,07444268 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02142655 0,0743304 ! reproductive behavior GO:0019098 12 7 0,000 0,02142655 0,07421845 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02142655 0,07410685 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02142655 0,07399558 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02142655 0,07388464 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02142655 0,07377403 ! oligopeptide transport GO:0006857 11 7 0,000 0,02142655 0,07366376 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02142655 0,07355381 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02142655 0,07344419 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02142655 0,0733349 ! RNA methylation GO:0001510 11 7 0,000 0,02142655 0,07322593 ! pericardium development GO:0060039 8 7 0,000 0,02142655 0,07311729 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02142655 0,07300897 ! fibril organization GO:0043206 13 7 0,000 0,02142655 0,07290097 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02142655 0,07279329 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02142655 0,07268592 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02142655 0,07257887 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02142655 0,07247214 ! lipoprotein transport GO:0042953 9 7 0,000 0,02142655 0,07236572 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02142655 0,07225961 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02142655 0,07215381 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02142655 0,07204832 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02142655 0,07194314 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02142655 0,07183827 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02142655 0,0717337 ! chemosensory behavior GO:0007635 9 7 0,000 0,02142655 0,07162944 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02142655 0,07152548 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02142655 0,07142182 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02142655 0,07131846 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02142655 0,0712154 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02142655 0,07111263 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02142655 0,07101016 ! reflex GO:0060004 12 7 0,000 0,02142655 0,07090799 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02142655 0,07080611 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02142655 0,07070453 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02142655 0,07060323 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02142655 0,07050222 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02142655 0,07040151 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02142655 0,07030108 ! spinal cord patterning GO:0021511 7 7 0,000 0,02142655 0,07020093 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02142655 0,07010107 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02142655 0,0700015 ! adrenal gland development GO:0030325 17 7 0,000 0,02142655 0,0699022 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02142655 0,06980319 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02142655 0,06970446 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02142655 0,06960601 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02142655 0,06950783 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02142655 0,06940994 ! endosome organization GO:0007032 10 7 0,000 0,02142655 0,06931231 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02142655 0,06921496 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02142655 0,06911789 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02142655 0,06902108 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02142655 0,06892455 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02142655 0,06882829 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02142655 0,06873229 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02142655 0,06863657 ! galactose metabolic process GO:0006012 10 7 0,000 0,02142655 0,0685411 ! vesicle fusion GO:0006906 15 7 0,000 0,02142655 0,06844591 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02142655 0,06835098 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02142655 0,06825631 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02142655 0,0681619 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02142655 0,06806775 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02142655 0,06797387 ! retinol metabolic process GO:0042572 9 7 0,000 0,02142655 0,06788024 ! behavioral fear response GO:0001662 13 7 0,000 0,02142655 0,06778687 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02142655 0,06769376 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02142655 0,0676009 ! rRNA modification GO:0000154 12 7 0,000 0,02142655 0,06750829 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02142655 0,06741594 ! response to UV-B GO:0010224 11 7 0,000 0,02142655 0,06732384 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02142655 0,067232 ! intermediate filament organization GO:0045109 11 7 0,000 0,02142655 0,0671404 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02142655 0,06704905 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02142655 0,06695795 ! fibrinolysis GO:0042730 9 7 0,000 0,02142655 0,0668671 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02142655 0,0667765 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02142655 0,06668614 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02142655 0,06659602 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02142655 0,06650615 ! response to tropane GO:0014073 13 7 0,000 0,02142655 0,06641651 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02142655 0,06632713 ! melanosome localization GO:0032400 10 7 0,000 0,02142655 0,06623798 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02142655 0,06614907 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02142655 0,06606039 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02142655 0,06597196 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02142655 0,06588376 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02142655 0,0657958 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02142655 0,06570807 ! mast cell activation GO:0045576 9 7 0,000 0,02142655 0,06562058 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02142655 0,06553332 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02142655 0,06544629 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02142655 0,06535949 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02142655 0,06527292 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02142655 0,06518658 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02142655 0,06510047 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02142655 0,06501458 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02142655 0,06492892 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02142655 0,06484349 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02142655 0,06475828 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02142655 0,0646733 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02142655 0,06458854 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02142655 0,064504 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02142655 0,06441968 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02142655 0,06433558 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02142655 0,0642517 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02142655 0,06416804 ! diuresis GO:0030146 12 7 0,000 0,02142655 0,0640846 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02142655 0,06400137 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02142655 0,06391836 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02142655 0,06383556 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02142655 0,06375298 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02142655 0,06367061 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02142655 0,06358846 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02142655 0,06350651 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02142655 0,06342478 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02142655 0,06334326 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02142655 0,06326194 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02142655 0,06318084 ! lymph node development GO:0048535 9 7 0,000 0,02142655 0,06309994 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02142655 0,06301925 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02142655 0,06293877 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02142655 0,06285849 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02142655 0,06277841 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02142655 0,06269854 ! ATP catabolic process GO:0006200 10 7 0,000 0,02142655 0,06261887 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02142655 0,06253941 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02142655 0,06246014 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02142655 0,06238108 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02142655 0,06230222 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02142655 0,06222355 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02142655 0,06214509 ! muscle adaptation GO:0043500 12 7 0,000 0,02142655 0,06206682 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02142655 0,06198875 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02142655 0,06191087 ! retina homeostasis GO:0001895 9 7 0,000 0,02142655 0,06183319 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02142655 0,06175571 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02142655 0,06167842 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02142655 0,06160132 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02142655 0,06152441 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02142655 0,0614477 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02142655 0,06137118 ! response to oxygen levels GO:0070482 137 74 1,000 0,02194939 0,06279054 ! protein import into nucleus GO:0006606 118 74 1,000 0,02194939 0,06271254 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,02194939 0,06263473 ! nuclear import GO:0051170 121 75 1,000 0,0225067 0,06414548 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,0236388 0,06728868 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02445046 0,06951306 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02445046 0,06942724 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,02445046 0,06934163 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02445046 0,06925624 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02445046 0,06917105 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02445046 0,06908608 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02445046 0,06900131 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02445046 0,06891675 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02445046 0,06883239 ! phosphate transport GO:0006817 10 8 0,000 0,02445046 0,06874825 ! N-glycan processing GO:0006491 12 8 0,000 0,02445046 0,0686643 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02445046 0,06858057 ! UTP metabolic process GO:0046051 8 8 0,000 0,02445046 0,06849703 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02445046 0,0684137 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02445046 0,06833058 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02445046 0,06824765 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02445046 0,06816493 ! succinate metabolic process GO:0006105 14 8 0,000 0,02445046 0,0680824 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02445046 0,06800008 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02445046 0,06791795 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02445046 0,06783603 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02445046 0,0677543 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02445046 0,06767276 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02445046 0,06759142 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02445046 0,06751028 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02445046 0,06742934 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02445046 0,06734858 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02445046 0,06726802 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02445046 0,06718765 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02445046 0,06710748 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02445046 0,06702749 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02445046 0,0669477 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02445046 0,06686809 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02445046 0,06678868 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,02445046 0,06670945 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02445046 0,06663041 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02445046 0,06655156 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02445046 0,06647289 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02445046 0,06639441 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02445046 0,06631611 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02445046 0,066238 ! melanin metabolic process GO:0006582 12 8 0,000 0,02445046 0,06616008 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02445046 0,06608233 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02445046 0,06600477 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02445046 0,06592739 ! macrophage activation GO:0042116 12 8 0,000 0,02445046 0,06585019 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02445046 0,06577318 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02445046 0,06569634 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02445046 0,06561968 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02445046 0,0655432 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02445046 0,0654669 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02445046 0,06539077 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02445046 0,06531483 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02445046 0,06523905 ! ruffle organization GO:0031529 11 8 0,000 0,02445046 0,06516346 ! osteoblast development GO:0002076 13 8 0,000 0,02445046 0,06508804 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02445046 0,06501279 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02445046 0,06493772 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02445046 0,06486282 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02445046 0,06478809 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02445046 0,06471354 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02445046 0,06463916 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02445046 0,06456494 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02445046 0,0644909 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02445046 0,06441703 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02445046 0,06434332 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02445046 0,06426979 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02445046 0,06419642 ! segment specification GO:0007379 10 8 0,000 0,02445046 0,06412322 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02445046 0,06405019 ! cellular extravasation GO:0045123 11 8 0,000 0,02445046 0,06397732 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02445046 0,06390462 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02445046 0,06383208 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02445046 0,06375971 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02445046 0,0636875 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02445046 0,06361546 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,02445046 0,06354358 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02445046 0,06347186 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02445046 0,0634003 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02445046 0,0633289 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02445046 0,06325767 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02445046 0,06318659 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02445046 0,06311567 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02445046 0,06304492 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02445046 0,06297432 ! icosanoid secretion GO:0032309 12 8 0,000 0,02445046 0,06290388 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02445046 0,06283359 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02445046 0,06276347 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02445046 0,0626935 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02445046 0,06262368 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02445046 0,06255402 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02445046 0,06248452 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02445046 0,06241517 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02445046 0,06234597 ! sterol catabolic process GO:0016127 9 8 0,000 0,02445046 0,06227693 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02445046 0,06220804 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02445046 0,0621393 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02445046 0,06207071 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02445046 0,06200228 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02445046 0,06193399 ! prophase GO:0051324 11 8 0,000 0,02445046 0,06186586 ! S phase GO:0051320 8 8 0,000 0,02445046 0,06179787 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02445046 0,06173004 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02445046 0,06166235 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02445046 0,06159481 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02445046 0,06152742 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02445046 0,06146018 ! hormone catabolic process GO:0042447 13 8 0,000 0,02445046 0,06139308 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02445046 0,06132613 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02445046 0,06125933 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02445046 0,06119267 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02445046 0,06112616 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02445046 0,06105979 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02445046 0,06099356 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02445046 0,06092748 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02445046 0,06086154 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02445046 0,06079575 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02445046 0,06073009 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02445046 0,06066458 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02445046 0,06059921 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02445046 0,06053398 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02445046 0,06046889 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02445046 0,06040394 ! T cell activation GO:0042110 134 79 1,000 0,02479397 0,06118683 ! protein localization in nucleus GO:0034504 133 80 1,000 0,0253801 0,06256616 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,02597187 0,06395643 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,02656926 0,06535753 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,02717221 0,06676931 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02746521 0,06741727 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02746521 0,0673454 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02746521 0,06727368 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02746521 0,06720211 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02746521 0,06713069 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02746521 0,06705943 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02746521 0,06698832 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02746521 0,06691735 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02746521 0,06684654 ! GTP metabolic process GO:0046039 9 9 0,000 0,02746521 0,06677588 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02746521 0,06670537 ! social behavior GO:0035176 14 9 0,000 0,02746521 0,066635 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02746521 0,06656479 ! artery development GO:0060840 19 9 0,000 0,02746521 0,06649472 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02746521 0,0664248 ! response to pain GO:0048265 16 9 0,000 0,02746521 0,06635502 ! protein complex disassembly GO:0043241 17 9 0,000 0,02746521 0,0662854 GO:0043624|cellular protein complex disassembly, ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02746521 0,06621591 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02746521 0,06614658 ! lung alveolus development GO:0048286 17 9 0,000 0,02746521 0,06607739 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02746521 0,06600834 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02746521 0,06593944 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02746521 0,06587068 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02746521 0,06580206 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02746521 0,06573359 ! protein targeting to ER GO:0045047 19 9 0,000 0,02746521 0,06566526 ! T cell selection GO:0045058 18 9 0,000 0,02746521 0,06559707 ! endoderm development GO:0007492 12 9 0,000 0,02746521 0,06552903 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02746521 0,06546112 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02746521 0,06539336 ! arginine catabolic process GO:0006527 10 9 0,000 0,02746521 0,06532573 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02746521 0,06525825 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02746521 0,0651909 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02746521 0,06512369 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02746521 0,06505662 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02746521 0,06498969 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02746521 0,0649229 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02746521 0,06485624 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02746521 0,06478972 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02746521 0,06472334 ! mannose metabolic process GO:0006013 9 9 0,000 0,02746521 0,06465709 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02746521 0,06459098 ! receptor clustering GO:0043113 15 9 0,000 0,02746521 0,06452501 ! epithelial cell development GO:0002064 10 9 0,000 0,02746521 0,06445916 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02746521 0,06439346 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02746521 0,06432788 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02746521 0,06426244 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02746521 0,06419714 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02746521 0,06413196 ! motor axon guidance GO:0008045 14 9 0,000 0,02746521 0,06406692 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02746521 0,06400201 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02746521 0,06393723 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02746521 0,06387258 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02746521 0,06380806 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02746521 0,06374367 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02746521 0,06367942 ! DNA ligation GO:0006266 14 9 0,000 0,02746521 0,06361529 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02746521 0,06355129 ! response to amine stimulus GO:0014075 13 9 0,000 0,02746521 0,06348742 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02746521 0,06342368 ! erythrocyte development GO:0048821 11 9 0,000 0,02746521 0,06336006 ! renal water homeostasis GO:0003091 14 9 0,000 0,02746521 0,06329657 ! postreplication repair GO:0006301 11 9 0,000 0,02746521 0,06323321 ! mRNA cleavage GO:0006379 13 9 0,000 0,02746521 0,06316998 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02746521 0,06310687 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02746521 0,06304389 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02746521 0,06298104 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02746521 0,06291831 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02746521 0,0628557 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02746521 0,06279322 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02746521 0,06273087 ! acid secretion GO:0046717 14 9 0,000 0,02746521 0,06266863 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02746521 0,06260652 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02746521 0,06254454 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02746521 0,06248267 ! purine base metabolic process GO:0006144 18 9 0,000 0,02746521 0,06242093 ! oocyte differentiation GO:0009994 12 9 0,000 0,02746521 0,06235931 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02746521 0,06229781 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02746521 0,06223644 ! spleen development GO:0048536 15 9 0,000 0,02746521 0,06217518 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02746521 0,06211404 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02746521 0,06205303 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02746521 0,06199213 ! detection of calcium ion GO:0005513 13 9 0,000 0,02746521 0,06193135 ! blastocyst formation GO:0001825 12 9 0,000 0,02746521 0,0618707 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02746521 0,06181016 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02746521 0,06174974 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02746521 0,06168944 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02746521 0,06162925 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02746521 0,06156918 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02746521 0,06150923 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02746521 0,0614494 ! prepulse inhibition GO:0060134 14 9 0,000 0,02746521 0,06138968 ! embryonic placenta development GO:0001892 12 9 0,000 0,02746521 0,06133008 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02746521 0,06127059 ! insulin secretion GO:0030073 17 9 0,000 0,02746521 0,06121122 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02746521 0,06115197 ! response to nicotine GO:0035094 16 9 0,000 0,02746521 0,06109283 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02746521 0,0610338 ! nucleus localization GO:0051647 15 9 0,000 0,02746521 0,06097489 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02746521 0,06091609 ! transcription initiation GO:0006352 118 85 1,000 0,02839465 0,06291686 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,02839465 0,06285631 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,02963891 0,06554759 GO:0060538|skeletal muscle organ development, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03047081 0,06732264 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03047081 0,06725803 ! neuron fate specification GO:0048665 11 10 0,000 0,03047081 0,06719354 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03047081 0,06712918 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03047081 0,06706494 ! thyroid gland development GO:0030878 19 10 0,000 0,03047081 0,06700083 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03047081 0,06693683 ! synapsis GO:0007129 13 10 0,000 0,03047081 0,06687296 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03047081 0,06680921 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03047081 0,06674559 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03047081 0,06668208 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03047081 0,06661869 ! sulfate transport GO:0008272 12 10 0,000 0,03047081 0,06655543 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03047081 0,06649228 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03047081 0,06642926 ! androgen metabolic process GO:0008209 13 10 0,000 0,03047081 0,06636635 ! phospholipid efflux GO:0033700 16 10 0,000 0,03047081 0,06630356 ! hippocampus development GO:0021766 19 10 0,000 0,03047081 0,06624089 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03047081 0,06617834 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03047081 0,06611591 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03047081 0,0660536 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03047081 0,0659914 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03047081 0,06592932 ! pathogenesis GO:0009405 13 10 0,000 0,03047081 0,06586735 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03047081 0,06580551 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03047081 0,06574378 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03047081 0,06568216 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03047081 0,06562066 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03047081 0,06555928 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03047081 0,06549801 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03047081 0,06543685 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03047081 0,06537581 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03047081 0,06531488 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03047081 0,06525406 ! B cell proliferation GO:0042100 14 10 0,000 0,03047081 0,06519336 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03047081 0,06513277 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03047081 0,0650723 ! forebrain cell migration GO:0021885 17 10 0,000 0,03047081 0,06501193 ! lipid digestion GO:0044241 15 10 0,000 0,03047081 0,06495168 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03047081 0,06489154 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03047081 0,06483151 ! UV protection GO:0009650 14 10 0,000 0,03047081 0,06477159 ! entry into host cell GO:0030260 20 10 0,000 0,03047081 0,06471179 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03047081 0,06465209 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03047081 0,0645925 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03047081 0,06453303 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03047081 0,06447366 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03047081 0,0644144 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03047081 0,06435525 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03047081 0,06429621 ! regulation of organ growth GO:0046620 11 10 0,000 0,03047081 0,06423727 ! response to dsRNA GO:0043331 18 10 0,000 0,03047081 0,06417845 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03047081 0,06411973 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03047081 0,06406112 ! embryonic axis specification GO:0000578 12 10 0,000 0,03047081 0,06400262 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03047081 0,06394422 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03047081 0,06388593 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03047081 0,06382775 ! cranial nerve development GO:0021545 12 10 0,000 0,03047081 0,06376967 ! fucose catabolic process GO:0019317 16 10 0,000 0,03047081 0,0637117 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03047081 0,06365383 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03047081 0,06359607 ! protein sumoylation GO:0016925 12 10 0,000 0,03047081 0,06353841 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03047081 0,06348086 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03047081 0,06342341 ! zymogen activation GO:0031638 14 10 0,000 0,03047081 0,06336606 ! salivary gland development GO:0007431 22 10 0,000 0,03047081 0,06330882 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03047081 0,06325168 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03047081 0,06319465 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03047081 0,06313772 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03047081 0,06308089 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03047081 0,06302416 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03047081 0,06296753 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03047081 0,06291101 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03047081 0,06285459 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03047081 0,06279827 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03047081 0,06274205 ! detection of bacterium GO:0016045 10 10 0,000 0,03047081 0,06268593 ! embryonic gut development GO:0048566 11 10 0,000 0,03047081 0,06262991 ! activation of innate immune response GO:0002218 10 10 0,000 0,03047081 0,06257399 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03047081 0,06251817 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03047081 0,06246245 ! developmental induction GO:0031128 13 10 0,000 0,03047081 0,06240683 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03047081 0,0623513 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03047081 0,06229588 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03047081 0,06224056 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03047081 0,06218533 ! reproductive developmental process GO:0003006 127 89 1,000 0,03090467 0,06301484 ! leukocyte differentiation GO:0002521 143 90 1,000 0,03154552 0,06426457 ! cell fate commitment GO:0045165 141 92 1,000 0,03284297 0,06684853 ! rRNA transcription GO:0009303 17 11 0,000 0,0334673 0,06805904 ! respiratory burst GO:0045730 14 11 0,000 0,0334673 0,06799892 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0334673 0,06793891 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0334673 0,06787899 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0334673 0,06781919 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,0334673 0,06775949 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,0334673 0,06769989 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0334673 0,0676404 ! RNA polyadenylation GO:0043631 19 11 0,000 0,0334673 0,06758102 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,0334673 0,06752174 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,0334673 0,06746256 ! mating GO:0007618 14 11 0,000 0,0334673 0,06740348 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,0334673 0,06734451 ! T cell proliferation GO:0042098 20 11 0,000 0,0334673 0,06728565 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0334673 0,06722688 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0334673 0,06716822 ! bone resorption GO:0045453 16 11 0,000 0,0334673 0,06710966 ! regulated secretory pathway GO:0045055 14 11 0,000 0,0334673 0,0670512 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0334673 0,06699285 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0334673 0,06693459 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,0334673 0,06687644 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0334673 0,06681839 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0334673 0,06676043 ! syncytium formation GO:0006949 15 11 0,000 0,0334673 0,06670258 ! plasma membrane organization GO:0007009 18 11 0,000 0,0334673 0,06664483 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0334673 0,06658718 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0334673 0,06652963 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0334673 0,06647218 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0334673 0,06641482 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0334673 0,06635757 ! adult heart development GO:0007512 11 11 0,000 0,0334673 0,06630041 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0334673 0,06624336 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,0334673 0,0661864 ! temperature homeostasis GO:0001659 16 11 0,000 0,0334673 0,06612954 ! L-glutamate transport GO:0015813 16 11 0,000 0,0334673 0,06607277 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0334673 0,06601611 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0334673 0,06595954 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0334673 0,06590306 ! stem cell development GO:0048864 29 11 0,000 0,0334673 0,06584669 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0334673 0,06579041 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0334673 0,06573423 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0334673 0,06567814 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0334673 0,06562215 ! vasoconstriction GO:0042310 15 11 0,000 0,0334673 0,06556625 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,0334673 0,06551045 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0334673 0,06545474 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0334673 0,06539913 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,0334673 0,06534362 ! ribosome assembly GO:0042255 13 11 0,000 0,0334673 0,06528819 ! histone deacetylation GO:0016575 13 11 0,000 0,0334673 0,06523286 ! chromatin silencing GO:0006342 19 11 0,000 0,0334673 0,06517763 ! nucleosome positioning GO:0016584 13 11 0,000 0,0334673 0,06512249 ! T cell homeostasis GO:0043029 20 11 0,000 0,0334673 0,06506744 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0334673 0,06501248 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0334673 0,06495762 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0334673 0,06490285 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0334673 0,06484817 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0334673 0,06479359 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,0334673 0,06473909 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,0334673 0,06468469 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0334673 0,06463038 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,0334673 0,06457616 ! male genitalia development GO:0030539 13 11 0,000 0,0334673 0,06452203 ! cholesterol efflux GO:0033344 19 11 0,000 0,0334673 0,06446799 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,0334673 0,06441404 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0334673 0,06436018 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0334673 0,06430642 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0334673 0,06425274 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,0334673 0,06419915 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0334673 0,06414565 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,0334673 0,06409224 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,0334673 0,06403892 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,0334673 0,06398569 ! lysogeny GO:0030069 18 11 0,000 0,0334673 0,06393254 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0334673 0,06387949 ! acrosome reaction GO:0007340 13 11 0,000 0,0334673 0,06382652 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,0334673 0,06377364 ! response to oxidative stress GO:0006979 141 94 1,000 0,03416118 0,06504198 ! angiogenesis GO:0001525 149 95 1,000 0,03482797 0,06625669 ! in utero embryonic development GO:0001701 147 96 1,000 0,03549984 0,06747904 ! lactation GO:0007595 20 12 0,000 0,03645469 0,06923682 ! reproductive cellular process GO:0048610 14 12 0,000 0,03645469 0,06917969 ! tRNA modification GO:0006400 14 12 0,000 0,03645469 0,06912266 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03645469 0,06906572 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03645469 0,06900888 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03645469 0,06895213 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03645469 0,06889547 ! non-recombinational repair GO:0000726 19 12 0,000 0,03645469 0,06883891 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03645469 0,06878243 ! peroxisomal transport GO:0043574 21 12 0,000 0,03645469 0,06872605 ! cartilage condensation GO:0001502 18 12 0,000 0,03645469 0,06866977 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03645469 0,06861357 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03645469 0,06855747 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03645469 0,06850146 ! heart looping GO:0001947 15 12 0,000 0,03645469 0,06844554 ! palate development GO:0060021 15 12 0,000 0,03645469 0,06838971 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03645469 0,06833397 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03645469 0,06827833 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03645469 0,06822277 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03645469 0,06816731 ! arginine metabolic process GO:0006525 13 12 0,000 0,03645469 0,06811193 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03645469 0,06805665 ! methionine metabolic process GO:0006555 13 12 0,000 0,03645469 0,06800145 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03645469 0,06794634 ! Golgi organization GO:0007030 18 12 0,000 0,03645469 0,06789133 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03645469 0,0678364 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03645469 0,06778156 ! monoamine transport GO:0015844 13 12 0,000 0,03645469 0,06772681 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03645469 0,06767214 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03645469 0,06761757 ! L-amino acid transport GO:0015807 20 12 0,000 0,03645469 0,06756308 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03645469 0,06750868 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03645469 0,06745437 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03645469 0,06740015 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03645469 0,06734601 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03645469 0,06729196 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03645469 0,067238 ! cerebellum development GO:0021549 13 12 0,000 0,03645469 0,06718412 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03645469 0,06713033 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03645469 0,06707663 ! histone methylation GO:0016571 15 12 0,000 0,03645469 0,06702301 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03645469 0,06696948 ! gland morphogenesis GO:0022612 23 12 0,000 0,03645469 0,06691603 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03645469 0,06686267 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03645469 0,06680939 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03645469 0,0667562 ! intestinal absorption GO:0050892 19 12 0,000 0,03645469 0,06670309 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03645469 0,06665007 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03645469 0,06659713 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03645469 0,06654428 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03645469 0,0664915 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03645469 0,06643882 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03645469 0,06638621 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03645469 0,06633369 ! microspike assembly GO:0030035 23 12 0,000 0,03645469 0,06628125 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03645469 0,0662289 ! response to cold GO:0009409 14 12 0,000 0,03645469 0,06617663 ! protein import GO:0017038 156 99 1,000 0,03754556 0,06810315 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,03823738 0,06930338 ! protein localization in organelle GO:0033365 161 100 1,000 0,03823738 0,06924881 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,03943302 0,07135795 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03943302 0,07130185 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03943302 0,07124584 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03943302 0,07118991 ! water transport GO:0006833 17 13 0,000 0,03943302 0,07113408 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03943302 0,07107833 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03943302 0,07102267 ! lipid localization GO:0010876 24 13 0,000 0,03943302 0,0709671 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03943302 0,07091161 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03943302 0,07085621 ! organelle fusion GO:0048284 28 13 0,000 0,03943302 0,0708009 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03943302 0,07074567 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03943302 0,07069053 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03943302 0,07063547 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03943302 0,0705805 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03943302 0,07052562 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03943302 0,07047082 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03943302 0,07041611 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03943302 0,07036148 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03943302 0,07030694 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,03943302 0,07025248 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,03943302 0,0701981 ! NAD metabolic process GO:0019674 21 13 0,000 0,03943302 0,07014381 ! exocrine system development GO:0035272 27 13 0,000 0,03943302 0,0700896 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03943302 0,07003548 ! bone mineralization GO:0030282 15 13 0,000 0,03943302 0,06998144 ! regulation of exocytosis GO:0017157 17 13 0,000 0,03943302 0,06992749 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,03943302 0,06987361 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03943302 0,06981982 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03943302 0,06976611 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03943302 0,06971249 ! genitalia development GO:0048806 15 13 0,000 0,03943302 0,06965895 ! cellular pigmentation GO:0033059 24 13 0,000 0,03943302 0,06960549 ! tissue regeneration GO:0042246 21 13 0,000 0,03943302 0,06955211 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03943302 0,06949881 ! cofactor transport GO:0051181 19 13 0,000 0,03943302 0,0694456 ! NADP metabolic process GO:0006739 18 13 0,000 0,03943302 0,06939246 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03943302 0,06933941 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03943302 0,06928644 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03943302 0,06923355 ! gas transport GO:0015669 18 13 0,000 0,03943302 0,06918074 ! regulation of RNA stability GO:0043487 28 13 0,000 0,03943302 0,06912801 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03943302 0,06907536 ! regulation of axon extension GO:0030516 23 13 0,000 0,03943302 0,06902279 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03943302 0,0689703 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03943302 0,06891789 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03943302 0,06886556 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03943302 0,06881331 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03943302 0,06876114 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,03943302 0,06870905 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04240232 0,07382689 ! superoxide anion generation GO:0042554 18 14 0,000 0,04240232 0,07377105 ! neuron maturation GO:0042551 21 14 0,000 0,04240232 0,07371529 ! regulation of S phase GO:0033261 18 14 0,000 0,04240232 0,07365961 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04240232 0,07360402 ! myotube differentiation GO:0014902 21 14 0,000 0,04240232 0,07354851 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,04240232 0,07349309 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04240232 0,07343775 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04240232 0,07338249 ! inositol metabolic process GO:0006020 20 14 0,000 0,04240232 0,07332731 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04240232 0,07327222 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04240232 0,07321721 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04240232 0,07316229 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04240232 0,07310744 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04240232 0,07305268 ! response to cAMP GO:0051591 19 14 0,000 0,04240232 0,072998 ! limbic system development GO:0021761 25 14 0,000 0,04240232 0,0729434 ! startle response GO:0001964 21 14 0,000 0,04240232 0,07288888 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04240232 0,07283445 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04240232 0,0727801 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04240232 0,07272582 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04240232 0,07267163 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04240232 0,07261752 ! glycine metabolic process GO:0006544 22 14 0,000 0,04240232 0,07256349 ! pituitary gland development GO:0021983 23 14 0,000 0,04240232 0,07250954 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04240232 0,07245567 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04240232 0,07240188 ! regulation of heart rate GO:0002027 23 14 0,000 0,04240232 0,07234817 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04240232 0,07229453 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04240232 0,07224098 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04240232 0,07218751 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04240232 0,07213412 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04240232 0,0720808 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04240232 0,07202757 ! axon cargo transport GO:0008088 27 14 0,000 0,04240232 0,07197441 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04240232 0,07192133 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04240232 0,07186833 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04240232 0,07181541 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04240232 0,07176257 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04240232 0,0717098 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04240232 0,07165711 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04240232 0,0716045 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04240232 0,07155196 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04240232 0,07149951 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04240232 0,07144713 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04240232 0,07139482 ! muscle maintenance GO:0046716 19 14 0,000 0,04240232 0,0713426 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04240232 0,07129044 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04240232 0,07123837 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04240232 0,07118637 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04240232 0,07113445 ! cell killing GO:0001906 20 14 0,000 0,04240232 0,0710826 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04240232 0,07103083 ! cilium assembly GO:0042384 20 14 0,000 0,04240232 0,07097913 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04240232 0,07092751 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,0453626 0,07582412 ! positive regulation of cell size GO:0045793 20 15 0,000 0,0453626 0,07576905 ! metencephalon development GO:0022037 19 15 0,000 0,0453626 0,07571407 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,0453626 0,07565916 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,0453626 0,07560434 ! skin development GO:0043588 25 15 0,000 0,0453626 0,07554959 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,0453626 0,07549492 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,0453626 0,07544034 ! lipid phosphorylation GO:0046834 23 15 0,000 0,0453626 0,07538583 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,0453626 0,0753314 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,0453626 0,07527705 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,0453626 0,07522277 ! bile acid metabolic process GO:0008206 22 15 0,000 0,0453626 0,07516858 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,0453626 0,07511446 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,0453626 0,07506042 ! adult walking behavior GO:0007628 25 15 0,000 0,0453626 0,07500646 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0453626 0,07495258 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,0453626 0,07489877 ! myoblast differentiation GO:0045445 27 15 0,000 0,0453626 0,07484504 ! centrosome cycle GO:0007098 16 15 0,000 0,0453626 0,07479139 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,0453626 0,07473781 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,0453626 0,07468431 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,0453626 0,07463089 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,0453626 0,07457754 ! cerebral cortex development GO:0021987 29 15 0,000 0,0453626 0,07452428 ! response to osmotic stress GO:0006970 22 15 0,000 0,0453626 0,07447108 ! vesicle coating GO:0006901 25 15 0,000 0,0453626 0,07441796 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,0453626 0,07436492 ! DNA integration GO:0015074 22 15 0,000 0,0453626 0,07431196 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,0453626 0,07425906 ! peptide secretion GO:0002790 27 15 0,000 0,0453626 0,07420625 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,0453626 0,07415351 ! regulation of vasodilation GO:0042312 24 15 0,000 0,0453626 0,07410084 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,0453626 0,07404825 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,0453626 0,07399573 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,0453626 0,07394329 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,0453626 0,07389092 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,0453626 0,07383863 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,0453626 0,07378641 ! biomineral formation GO:0031214 18 15 0,000 0,0453626 0,07373427 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,0453626 0,07368219 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,0453626 0,07363019 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,0453626 0,07357827 ! dopamine metabolic process GO:0042417 30 15 0,000 0,0453626 0,07352642 ! organic cation transport GO:0015695 19 15 0,000 0,0453626 0,07347464 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,0453626 0,07342293 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,0453626 0,0733713 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,0453626 0,07331974 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,0453626 0,07326825 ! peptide hormone processing GO:0016486 19 15 0,000 0,0453626 0,07321683 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,0453626 0,07316549 ! protein secretion GO:0009306 27 16 0,000 0,04831391 0,07787105 ! hormone secretion GO:0046879 25 16 0,000 0,04831391 0,07781651 ! bone remodeling GO:0046849 24 16 0,000 0,04831391 0,07776206 ! endothelial cell migration GO:0043542 22 16 0,000 0,04831391 0,07770768 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04831391 0,07765338 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04831391 0,07759915 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04831391 0,077545 ! glial cell development GO:0021782 24 16 0,000 0,04831391 0,07749092 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04831391 0,07743692 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04831391 0,077383 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04831391 0,07732915 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04831391 0,07727537 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04831391 0,07722167 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04831391 0,07716804 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04831391 0,07711449 ! fructose metabolic process GO:0006000 20 16 0,000 0,04831391 0,07706101 ! regulation of protein binding GO:0043393 27 16 0,000 0,04831391 0,07700761 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04831391 0,07695428 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04831391 0,07690103 ! protein export from nucleus GO:0006611 24 16 0,000 0,04831391 0,07684784 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04831391 0,07679474 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04831391 0,0767417 ! DNA replication initiation GO:0006270 25 16 0,000 0,04831391 0,07668874 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04831391 0,07663585 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04831391 0,07658303 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04831391 0,07653029 ! diencephalon development GO:0021536 25 16 0,000 0,04831391 0,07647762 ! oogenesis GO:0048477 23 16 0,000 0,04831391 0,07642502 ! neural crest cell migration GO:0001755 24 16 0,000 0,04831391 0,0763725 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04831391 0,07632004 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04831391 0,07626766 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04831391 0,07621535 ! steroid catabolic process GO:0006706 22 16 0,000 0,04831391 0,07616311 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04831391 0,07611095 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04831391 0,07605885 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04831391 0,07600683 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04831391 0,07595488 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04831391 0,07590299 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04831391 0,07585118 ! nerve development GO:0021675 18 16 0,000 0,04831391 0,07579944 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04831391 0,07574777 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04831391 0,07569617 ! negative regulation of translation GO:0017148 22 16 0,000 0,04831391 0,07564464 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05125625 0,08019686 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05125625 0,08014234 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05125625 0,0800879 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05125625 0,08003353 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05125625 0,07997923 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05125625 0,07992501 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05125625 0,07987086 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05125625 0,07981678 ! signal complex assembly GO:0007172 29 17 0,000 0,05125625 0,07976278 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05125625 0,07970885 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05125625 0,07965499 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05125625 0,0796012 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05125625 0,07954749 ! memory GO:0007613 25 17 0,000 0,05125625 0,07949385 ! keratinization GO:0031424 17 17 0,000 0,05125625 0,07944029 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05125625 0,07938679 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05125625 0,07933337 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05125625 0,07928002 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05125625 0,07922674 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,05125625 0,07917353 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05125625 0,07912039 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05125625 0,07906733 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05125625 0,07901433 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05125625 0,07896141 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05125625 0,07890856 ! membrane budding GO:0006900 29 17 0,000 0,05125625 0,07885577 ! heme metabolic process GO:0042168 27 17 0,000 0,05125625 0,07880306 ! neuromuscular junction development GO:0007528 23 17 0,000 0,05125625 0,07875042 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,05125625 0,07869785 ! body fluid secretion GO:0007589 27 17 0,000 0,05125625 0,07864535 ! stem cell differentiation GO:0048863 36 17 0,000 0,05125625 0,07859292 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05125625 0,07854056 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05125625 0,07848827 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05125625 0,07843605 ! sensory perception of pain GO:0019233 23 17 0,000 0,05125625 0,0783839 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05125625 0,07833182 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05125625 0,0782798 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,05125625 0,07822786 ! synaptogenesis GO:0007416 24 17 0,000 0,05125625 0,07817598 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,05125625 0,07812418 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05125625 0,07807244 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05125625 0,07802077 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05125625 0,07796917 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05125625 0,07791764 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05125625 0,07786617 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05125625 0,07781477 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,05125625 0,07776345 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05125625 0,07771218 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05125625 0,07766099 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,05418967 0,08205151 ! positive regulation of translation GO:0045727 28 18 0,000 0,05418967 0,08199753 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,05418967 0,08194362 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05418967 0,08188978 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05418967 0,08183601 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05418967 0,08178231 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05418967 0,08172869 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05418967 0,08167513 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05418967 0,08162164 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05418967 0,08156822 ! axis specification GO:0009798 26 18 0,000 0,05418967 0,08151488 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05418967 0,0814616 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05418967 0,08140839 ! pancreas development GO:0031016 26 18 0,000 0,05418967 0,08135525 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05418967 0,08130218 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05418967 0,08124918 ! response to retinoic acid GO:0032526 25 18 0,000 0,05418967 0,08119625 ! pigmentation during development GO:0048066 31 18 0,000 0,05418967 0,08114339 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05418967 0,0810906 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,05418967 0,08103787 ! fucose metabolic process GO:0006004 26 18 0,000 0,05418967 0,08098522 ! response to fungus GO:0009620 19 18 0,000 0,05418967 0,08093263 ! peptide cross-linking GO:0018149 31 18 0,000 0,05418967 0,08088011 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05418967 0,08082766 ! heart process GO:0003015 27 18 0,000 0,05418967 0,08077527 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05418967 0,08072296 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05418967 0,08067071 ! visual learning GO:0008542 35 18 0,000 0,05418967 0,08061853 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05418967 0,08056642 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,05418967 0,08051437 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05418967 0,08046239 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05418967 0,08041048 ! vitamin transport GO:0051180 24 18 0,000 0,05418967 0,08035864 ! hormone transport GO:0009914 27 18 0,000 0,05418967 0,08030686 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05418967 0,08025515 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05418967 0,08020351 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05418967 0,08015193 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05418967 0,08010042 ! cell-cell recognition GO:0009988 20 18 0,000 0,05418967 0,08004897 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05418967 0,07999759 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05418967 0,07994628 ! regulation of glucose import GO:0046324 21 18 0,000 0,05418967 0,07989503 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,05418967 0,07984385 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05418967 0,07979273 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,05418967 0,07974168 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,05711419 0,08399145 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,05711419 0,08393779 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05711419 0,08388419 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05711419 0,08383065 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05711419 0,08377719 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05711419 0,0837238 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05711419 0,08367047 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,05711419 0,08361721 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05711419 0,08356402 ! regeneration GO:0031099 32 19 0,000 0,05711419 0,08351089 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05711419 0,08345784 ! response to alkaloid GO:0043279 32 19 0,000 0,05711419 0,08340485 ! sensory perception of taste GO:0050909 23 19 0,000 0,05711419 0,08335193 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05711419 0,08329907 ! peroxisome organization GO:0007031 29 19 0,000 0,05711419 0,08324628 ! digestive system process GO:0022600 30 19 0,000 0,05711419 0,08319356 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,05711419 0,08314091 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05711419 0,08308832 ! response to vitamin A GO:0033189 26 19 0,000 0,05711419 0,0830358 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05711419 0,08298335 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05711419 0,08293096 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,05711419 0,08287863 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,05711419 0,08282638 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05711419 0,08277419 ! plasma membrane fusion GO:0045026 23 19 0,000 0,05711419 0,08272206 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,05711419 0,08267 ! cytolysis GO:0019835 20 19 0,000 0,05711419 0,08261801 ! renal system process GO:0003014 35 19 0,000 0,05711419 0,08256608 ! vasodilation GO:0042311 33 19 0,000 0,05711419 0,08251422 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05711419 0,08246242 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05711419 0,08241069 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05711419 0,08235902 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05711419 0,08230742 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05711419 0,08225588 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05711419 0,0822044 ! sarcomere organization GO:0045214 23 19 0,000 0,05711419 0,08215299 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05711419 0,08210165 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,05711419 0,08205037 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05711419 0,08199915 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05711419 0,08194799 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05711419 0,0818969 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,05711419 0,08184588 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05711419 0,08179492 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,05711419 0,08174402 ! protein stabilization GO:0050821 26 19 0,000 0,05711419 0,08169318 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,06002983 0,0858102 ! iron ion transport GO:0006826 37 20 0,000 0,06002983 0,0857569 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,06002983 0,08570367 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,06002983 0,0856505 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,06002983 0,0855974 ! response to vitamin GO:0033273 29 20 0,000 0,06002983 0,08554437 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,06002983 0,0854914 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,06002983 0,0854385 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,06002983 0,08538566 ! spinal cord development GO:0021510 31 20 0,000 0,06002983 0,08533289 ! response to ethanol GO:0045471 37 20 0,000 0,06002983 0,08528018 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,06002983 0,08522754 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,06002983 0,08517496 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,06002983 0,08512245 ! chromosome condensation GO:0030261 31 20 0,000 0,06002983 0,08507 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,06002983 0,08501762 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,06002983 0,0849653 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,06002983 0,08491304 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,06002983 0,08486085 ! pallium development GO:0021543 38 20 0,000 0,06002983 0,08480873 ! DNA modification GO:0006304 28 20 0,000 0,06002983 0,08475667 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,06002983 0,08470467 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,06002983 0,08465273 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,06002983 0,08460086 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,06002983 0,08454906 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,06002983 0,08449731 ! collagen catabolic process GO:0030574 25 20 0,000 0,06002983 0,08444563 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,06002983 0,08439402 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,06002983 0,08434246 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,06002983 0,08429097 ! alditol metabolic process GO:0019400 24 20 0,000 0,06002983 0,08423954 ! actin filament-based movement GO:0030048 34 20 0,000 0,06002983 0,08418818 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,06293662 0,08821099 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,06293662 0,08815726 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,06293662 0,08810361 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,06293662 0,08805002 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,06293662 0,08799649 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,06293662 0,08794303 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,06293662 0,08788964 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,06293662 0,0878363 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,06293662 0,08778304 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,06293662 0,08772984 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,06293662 0,0876767 ! vesicle docking GO:0048278 27 21 0,000 0,06293662 0,08762363 ! phototransduction GO:0007602 25 21 0,000 0,06293662 0,08757062 ! dendrite development GO:0016358 35 21 0,000 0,06293662 0,08751767 ! visual behavior GO:0007632 39 21 0,000 0,06293662 0,08746479 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,06293662 0,08741197 ! ovarian follicle development GO:0001541 30 21 0,000 0,06293662 0,08735922 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,06293662 0,08730653 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,06293662 0,08725391 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,06293662 0,08720134 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,06293662 0,08714884 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,06293662 0,08709641 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,06293662 0,08704403 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,06293662 0,08699172 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,06293662 0,08693948 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,06293662 0,08688729 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,06293662 0,08683517 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,06293662 0,08678311 ! fatty acid transport GO:0015908 30 21 0,000 0,06293662 0,08673111 ! immunoglobulin production GO:0002377 33 21 0,000 0,06293662 0,08667918 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,06293662 0,08662731 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,06293662 0,0865755 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,06293662 0,08652375 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,06293662 0,08647206 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,06293662 0,08642044 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,06293662 0,08636887 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,06293662 0,08631737 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,06293662 0,08626593 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,06293662 0,08621455 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,06293662 0,08616323 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,06293662 0,08611197 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,06293662 0,08606078 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,06293662 0,08600964 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,06293662 0,08595857 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06583459 0,08986324 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,06583459 0,08980994 ! viral genome replication GO:0019079 29 22 0,000 0,06583459 0,0897567 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06583459 0,08970353 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,06583459 0,08965042 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06583459 0,08959737 ! molting cycle process GO:0022404 40 22 0,000 0,06583459 0,08954439 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06583459 0,08949146 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06583459 0,0894386 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,06583459 0,08938581 ! vasculogenesis GO:0001570 33 22 0,000 0,06583459 0,08933307 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,06583459 0,0892804 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06583459 0,08922779 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06583459 0,08917524 ! lysosome organization GO:0007040 37 22 0,000 0,06583459 0,08912275 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06583459 0,08907033 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,06583459 0,08901796 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06583459 0,08896566 ! regulation of behavior GO:0050795 38 22 0,000 0,06583459 0,08891342 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06583459 0,08886124 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06583459 0,08880912 ! membrane depolarization GO:0051899 35 22 0,000 0,06583459 0,08875707 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06583459 0,08870507 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06583459 0,08865314 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06583459 0,08860126 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06583459 0,08854945 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06583459 0,08849769 ! blastocyst development GO:0001824 37 22 0,000 0,06583459 0,088446 ! neural tube closure GO:0001843 33 22 0,000 0,06583459 0,08839437 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06583459 0,0883428 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06872376 0,09216598 ! neuron fate commitment GO:0048663 32 23 0,000 0,06872376 0,09211227 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06872376 0,09205862 ! myelination GO:0042552 35 23 0,000 0,06872376 0,09200503 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06872376 0,09195151 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06872376 0,09189805 ! vesicle targeting GO:0006903 32 23 0,000 0,06872376 0,09184465 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06872376 0,09179132 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06872376 0,09173804 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06872376 0,09168483 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06872376 0,09163168 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06872376 0,09157859 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06872376 0,09152556 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06872376 0,0914726 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06872376 0,09141969 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06872376 0,09136685 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06872376 0,09131407 ! cell fate determination GO:0001709 45 23 0,000 0,06872376 0,09126135 ! pentose metabolic process GO:0019321 31 23 0,000 0,06872376 0,09120868 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06872376 0,09115608 ! spermatid development GO:0007286 33 23 0,000 0,06872376 0,09110354 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06872376 0,09105107 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06872376 0,09099865 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06872376 0,09094629 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06872376 0,09089399 ! telomere organization GO:0032200 32 23 0,000 0,06872376 0,09084175 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,06872376 0,09078957 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06872376 0,09073746 ! regulation of amine transport GO:0051952 38 23 0,000 0,06872376 0,0906854 ! liver development GO:0001889 40 23 0,000 0,06872376 0,0906334 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,07160416 0,09437798 ! initiation of viral infection GO:0019059 42 24 0,000 0,07160416 0,09432392 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,07160416 0,09426993 ! superoxide metabolic process GO:0006801 32 24 0,000 0,07160416 0,094216 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,07160416 0,09416213 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,07160416 0,09410833 ! fat cell differentiation GO:0045444 37 24 0,000 0,07160416 0,09405458 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,07160416 0,0940009 ! sperm motility GO:0030317 27 24 0,000 0,07160416 0,09394727 ! vacuole organization GO:0007033 39 24 0,000 0,07160416 0,09389371 ! receptor metabolic process GO:0043112 37 24 0,000 0,07160416 0,09384021 ! neural crest cell development GO:0014032 39 24 0,000 0,07160416 0,09378677 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,07160416 0,09373339 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,07160416 0,09368007 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,07160416 0,09362682 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,07160416 0,09357362 ! glutathione metabolic process GO:0006749 29 24 0,000 0,07160416 0,09352048 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,07160416 0,09346741 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,07160416 0,09341439 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,07447582 0,09710566 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,07447582 0,09705064 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,07447582 0,09699569 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,07447582 0,09694079 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,07447582 0,09688596 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,07447582 0,09683119 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,07447582 0,09677649 ! peptide transport GO:0015833 43 25 0,000 0,07447582 0,09672184 ! male gonad development GO:0008584 33 25 0,000 0,07447582 0,09666726 ! iron ion homeostasis GO:0055072 39 25 0,000 0,07447582 0,09661274 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,07447582 0,09655828 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,07447582 0,09650388 ! phospholipid transport GO:0015914 35 25 0,000 0,07447582 0,09644954 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,07447582 0,09639526 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,07447582 0,09634105 ! detection of light stimulus GO:0009583 30 25 0,000 0,07447582 0,09628689 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,07447582 0,0962328 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,07447582 0,09617877 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,07447582 0,09612479 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07733876 0,09976396 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,07733876 0,09970804 ! circadian rhythm GO:0007623 42 26 0,000 0,07733876 0,09965218 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07733876 0,09959638 ! post-embryonic development GO:0009791 42 26 0,000 0,07733876 0,09954065 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07733876 0,09948498 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07733876 0,09942937 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07733876 0,09937382 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,07733876 0,09931834 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,07733876 0,09926291 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07733876 0,09920755 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,07733876 0,09915225 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07733876 0,09909701 ! regulation of coagulation GO:0050818 39 26 0,000 0,07733876 0,09904184 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,080193 0,1026399 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,080193 0,10258282 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,080193 0,10252579 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,080193 0,10246883 ! membrane docking GO:0022406 39 27 0,000 0,080193 0,10241194 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,080193 0,10235511 ! catechol metabolic process GO:0009712 43 27 0,000 0,080193 0,10229834 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,080193 0,10224163 ! acute-phase response GO:0006953 42 27 0,000 0,080193 0,10218499 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,080193 0,10212841 ! myofibril assembly GO:0030239 36 27 0,000 0,080193 0,10207189 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,080193 0,10201543 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,080193 0,10195904 ! natural killer cell activation GO:0030101 35 27 0,000 0,080193 0,10190271 ! lipid oxidation GO:0034440 38 27 0,000 0,080193 0,10184644 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,080193 0,10179023 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,080193 0,10173409 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,080193 0,10167801 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,080193 0,10162198 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,080193 0,10156603 ! gene silencing GO:0016458 41 27 0,000 0,080193 0,10151013 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,08303858 0,10505431 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,08303858 0,10499656 ! phenol metabolic process GO:0018958 44 28 0,000 0,08303858 0,10493886 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,08303858 0,10488124 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,08303858 0,10482367 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,08303858 0,10476617 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,08303858 0,10470874 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,08303858 0,10465136 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,08303858 0,10459405 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,08303858 0,1045368 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,08303858 0,10447961 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,08303858 0,10442249 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,08303858 0,10436543 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,08303858 0,10430843 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,08303858 0,10425149 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,08303858 0,10419462 ! mesoderm formation GO:0001707 46 28 0,000 0,08303858 0,1041378 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,08303858 0,10408105 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,08303858 0,10402436 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,08303858 0,10396774 ! ensheathment of neurons GO:0007272 43 28 0,000 0,08303858 0,10391117 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,08303858 0,10385467 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,08303858 0,10379822 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,08303858 0,10374184 ! neural tube formation GO:0001841 41 28 0,000 0,08303858 0,10368552 ! placenta development GO:0001890 37 28 0,000 0,08303858 0,10362926 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,08587552 0,10711155 ! regulation of innate immune response GO:0045088 38 29 0,000 0,08587552 0,10705349 ! ovulation cycle process GO:0022602 41 29 0,000 0,08587552 0,1069955 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,08587552 0,10693757 ! protein targeting to membrane GO:0006612 53 29 0,000 0,08587552 0,1068797 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,08587552 0,1068219 ! mismatch repair GO:0006298 34 29 0,000 0,08587552 0,10676416 ! muscle cell development GO:0055001 38 29 0,000 0,08587552 0,10670648 ! formation of primary germ layer GO:0001704 48 29 0,000 0,08587552 0,10664886 ! telencephalon development GO:0021537 52 29 0,000 0,08587552 0,10659131 ! eye morphogenesis GO:0048592 51 29 0,000 0,08587552 0,10653381 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,08587552 0,10647638 ! tissue homeostasis GO:0001894 42 29 0,000 0,08587552 0,10641901 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,08870384 0,10986475 ! collagen metabolic process GO:0032963 40 30 0,000 0,08870384 0,10980562 ! organic anion transport GO:0015711 51 30 0,000 0,08870384 0,10974655 ! cholesterol transport GO:0030301 46 30 0,000 0,08870384 0,10968755 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,08870384 0,10962861 ! spliceosome assembly GO:0000245 49 30 0,000 0,08870384 0,10956973 ! spindle organization GO:0007051 37 30 0,000 0,08870384 0,10951091 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,08870384 0,10945216 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,08870384 0,10939348 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,08870384 0,10933485 ! ceramide metabolic process GO:0006672 43 30 0,000 0,08870384 0,10927629 ! ovulation cycle GO:0042698 43 30 0,000 0,08870384 0,10921779 ! hindbrain development GO:0030902 45 30 0,000 0,08870384 0,10915935 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,08870384 0,10910098 ! adult locomotory behavior GO:0008344 47 30 0,000 0,08870384 0,10904267 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,08870384 0,10898442 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,08870384 0,10892623 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,08870384 0,10886811 ! response to heat GO:0009408 41 30 0,000 0,08870384 0,10881004 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,08870384 0,10875204 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,08870384 0,1086941 ! mammary gland development GO:0030879 57 31 0,000 0,09152357 0,11208957 ! glial cell differentiation GO:0010001 55 31 0,000 0,09152357 0,11202992 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,09152357 0,11197033 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,09152357 0,1119108 ! odontogenesis GO:0042476 50 31 0,000 0,09152357 0,11185134 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,09152357 0,11179194 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,09152357 0,1117326 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,09152357 0,11167333 ! metanephros development GO:0001656 58 31 0,000 0,09152357 0,11161412 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,09152357 0,11155497 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,09152357 0,11149588 ! cell fate specification GO:0001708 37 31 0,000 0,09152357 0,11143686 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,09152357 0,1113779 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,09152357 0,111319 ! RNA modification GO:0009451 40 31 0,000 0,09152357 0,11126016 ! regulation of muscle development GO:0048634 48 32 0,000 0,09433474 0,11461696 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,09433474 0,11455645 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,09433474 0,114496 ! meiosis I GO:0007127 52 32 0,000 0,09433474 0,11443561 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,09433474 0,11437528 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,09433474 0,11431502 ! peripheral nervous system development GO:0007422 53 32 0,000 0,09433474 0,11425482 ! regulation of protein stability GO:0031647 48 32 0,000 0,09433474 0,11419469 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,09433474 0,11413462 ! cytokine production GO:0001816 44 32 0,000 0,09433474 0,11407461 ! vesicle localization GO:0051648 47 32 0,000 0,09433474 0,11401467 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,09713738 0,11734032 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,09713738 0,11727872 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,09713738 0,11721719 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,09713738 0,11715572 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,09713738 0,11709432 ! sister chromatid segregation GO:0000819 46 33 0,000 0,09713738 0,11703298 ! ear morphogenesis GO:0042471 42 33 0,000 0,09713738 0,11697171 ! actomyosin structure organization GO:0031032 43 33 0,000 0,09713738 0,1169105 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,09713738 0,11684935 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,09713738 0,11678827 ! nucleus organization GO:0006997 49 33 0,000 0,09713738 0,11672725 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,09713738 0,1166663 ! female gonad development GO:0008585 49 33 0,000 0,09713738 0,11660541 ! positive regulation of cell development GO:0010720 54 33 0,000 0,09713738 0,11654458 ! lipid homeostasis GO:0055088 55 33 0,000 0,09713738 0,11648382 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,09713738 0,11642312 ! regulation of proteolysis GO:0030162 50 33 0,000 0,09713738 0,11636248 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,09713738 0,11630191 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,09713738 0,1162414 ! cytokinesis GO:0000910 52 33 0,000 0,09713738 0,11618095 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,09713738 0,11612056 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,0999315 0,11939867 ! mRNA catabolic process GO:0006402 48 34 0,000 0,0999315 0,11933668 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,0999315 0,11927475 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,0999315 0,11921288 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,0999315 0,11915108 ! feeding behavior GO:0007631 45 34 0,000 0,0999315 0,11908935 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,0999315 0,11902767 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,0999315 0,11896607 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,0999315 0,11890452 ! female gamete generation GO:0007292 43 34 0,000 0,0999315 0,11884304 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,0999315 0,11878162 ! polyol metabolic process GO:0019751 44 34 0,000 0,0999315 0,11872027 ! aerobic respiration GO:0009060 47 34 0,000 0,0999315 0,11865898 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,0999315 0,11859775 ! embryonic organ development GO:0048568 45 34 0,000 0,0999315 0,11853659 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,0999315 0,11847548 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,10271713 0,1217153 ! Notch signaling pathway GO:0007219 56 35 0,000 0,10271713 0,12165262 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,10271713 0,12159001 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,10271713 0,12152746 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,10271713 0,12146498 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,10271713 0,12140257 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,10271713 0,12134021 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,10271713 0,12127792 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,10271713 0,1212157 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,10271713 0,12115353 ! glycogen metabolic process GO:0005977 48 35 0,000 0,10271713 0,12109144 ! pigment metabolic process GO:0042440 61 35 0,000 0,10271713 0,1210294 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,1054943 0,12423803 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,1054943 0,12417445 ! tissue remodeling GO:0048771 62 36 0,000 0,1054943 0,12411094 ! neural tube development GO:0021915 50 36 0,000 0,1054943 0,12404749 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1054943 0,1239841 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1054943 0,12392078 ! glucan metabolic process GO:0044042 49 36 0,000 0,1054943 0,12385752 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,10826303 0,12704335 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,10826303 0,12697857 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,10826303 0,12691385 ! learning GO:0007612 67 37 0,000 0,10826303 0,12684919 ! ion transmembrane transport GO:0034220 56 37 0,000 0,10826303 0,12678461 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,10826303 0,12672008 ! regulation of protein secretion GO:0050708 51 37 0,000 0,10826303 0,12665563 ! amino acid activation GO:0043038 52 37 0,000 0,10826303 0,12659124 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,10826303 0,12652691 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,11102335 0,129687 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,11102335 0,12962117 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,11102335 0,12955541 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,11102335 0,12948971 ! phagocytosis GO:0006909 60 38 0,000 0,11102335 0,12942408 ! mesenchymal cell development GO:0014031 64 38 0,000 0,11102335 0,12935851 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,11102335 0,12929301 ! maintenance of location in cell GO:0051651 69 38 0,000 0,11102335 0,12922758 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,11377528 0,13236376 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,11377528 0,13229684 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,11377528 0,13222999 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,11377528 0,13216321 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,11377528 0,13209649 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,11377528 0,13202984 ! male sex differentiation GO:0046661 53 39 0,000 0,11377528 0,13196326 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,11377528 0,13189675 ! chromatin remodeling GO:0006338 68 39 0,000 0,11377528 0,1318303 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,11377528 0,13176392 ! JNK cascade GO:0007254 54 39 0,000 0,11377528 0,13169761 ! developmental growth GO:0048589 62 39 0,000 0,11377528 0,13163136 ! synapse organization GO:0050808 55 39 0,000 0,11377528 0,13156518 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,11651886 0,13467003 ! response to calcium ion GO:0051592 58 40 0,000 0,11651886 0,1346024 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,11651886 0,13453482 ! regulation of tube size GO:0035150 60 40 0,000 0,11651886 0,13446732 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,11651886 0,13439988 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,11651886 0,13433252 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,11651886 0,13426522 ! peptide metabolic process GO:0006518 56 40 0,000 0,11651886 0,13419798 ! inner ear development GO:0048839 57 40 0,000 0,11651886 0,13413082 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,11651886 0,13406372 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,11651886 0,13399668 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,11651886 0,13392972 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,11925409 0,1370052 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,11925409 0,1369368 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,11925409 0,13686847 ! glucose transport GO:0015758 52 41 0,000 0,11925409 0,13680021 ! endosome transport GO:0016197 71 41 0,000 0,11925409 0,13673201 ! striated muscle contraction GO:0006941 62 41 0,000 0,11925409 0,13666388 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,11925409 0,13659582 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,11925409 0,13652783 ! biopolymer methylation GO:0043414 62 41 0,000 0,11925409 0,13645991 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,11925409 0,13639205 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,12198102 0,13944152 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,12198102 0,13937225 ! cellular component disassembly GO:0022411 64 42 0,000 0,12198102 0,13930305 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,12198102 0,13923391 ! hexose transport GO:0008645 54 42 0,000 0,12198102 0,13916485 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,12198102 0,13909585 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,12198102 0,13902693 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,12198102 0,13895807 ! excretion GO:0007588 63 42 0,000 0,12198102 0,13888928 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,12198102 0,13882055 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,12198102 0,1387519 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,12198102 0,13868331 ! regulation of cell shape GO:0008360 78 42 0,000 0,12198102 0,13861479 ! leukocyte migration GO:0050900 60 43 0,000 0,12469965 0,14163417 ! neuromuscular process GO:0050905 79 43 0,000 0,12469965 0,14156427 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,12469965 0,14149443 ! tRNA processing GO:0008033 49 43 0,000 0,12469965 0,14142466 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,12469965 0,14135495 ! vesicle organization GO:0016050 79 43 0,000 0,12469965 0,14128532 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,12469965 0,14121576 ! methylation GO:0032259 64 43 0,000 0,12469965 0,14114626 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,12741003 0,14414317 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,12741003 0,1440723 ! glycolysis GO:0006096 53 44 0,000 0,12741003 0,1440015 ! regulation of action potential GO:0001508 71 44 0,000 0,12741003 0,14393078 ! regulation of ion transport GO:0043269 57 44 0,000 0,12741003 0,14386012 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,12741003 0,14378953 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,12741003 0,14371901 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,12741003 0,14364856 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,12741003 0,14357818 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,12741003 0,14350787 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,12741003 0,14343762 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,12741003 0,14336745 ! RNA catabolic process GO:0006401 64 45 0,000 0,13011216 0,14633642 ! positive regulation of defense response GO:0031349 59 45 0,000 0,13011216 0,1462649 ! regulation of translational initiation GO:0006446 64 45 0,000 0,13011216 0,14619344 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,13011216 0,14612206 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,13011216 0,14605074 ! cell maturation GO:0048469 60 45 0,000 0,13011216 0,1459795 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,13280609 0,1489293 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,13280609 0,14885673 ! cell redox homeostasis GO:0045454 63 46 0,000 0,13280609 0,14878422 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,13280609 0,14871178 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,13280609 0,14863942 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,13549182 0,15157159 ! viral infectious cycle GO:0019058 71 47 0,000 0,13549182 0,1514979 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,13549182 0,15142429 ! endocrine system development GO:0035270 83 47 0,000 0,13549182 0,15135075 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,13549182 0,15127728 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,13549182 0,15120388 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,13549182 0,15113055 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,13549182 0,15105729 ! chloride transport GO:0006821 67 48 0,000 0,13816939 0,15396783 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,13816939 0,15389327 ! response to temperature stimulus GO:0009266 62 48 0,000 0,13816939 0,15381878 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,13816939 0,15374436 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,13816939 0,15367002 ! gastrulation GO:0007369 73 48 0,000 0,13816939 0,15359575 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,13816939 0,15352155 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,13816939 0,15344742 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,13816939 0,15337336 ! regulation of endocytosis GO:0030100 63 48 0,000 0,13816939 0,15329937 ! nuclear export GO:0051168 69 48 0,000 0,13816939 0,15322546 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,13816939 0,15315162 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,13816939 0,15307784 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,14083882 0,15596018 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,14083882 0,15588513 ! sensory perception of smell GO:0007608 61 49 0,000 0,14083882 0,15581015 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,14083882 0,15573524 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,14083882 0,1556604 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,14083882 0,15558564 ! germ cell development GO:0007281 68 49 0,000 0,14083882 0,15551094 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,14083882 0,15543632 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,14083882 0,15536177 ! cartilage development GO:0051216 70 49 0,000 0,14083882 0,15528729 ! maintenance of location GO:0051235 84 49 0,000 0,14083882 0,15521289 ! regulation of actin filament length GO:0030832 72 50 0,000 0,14350014 0,15807008 ! ear development GO:0043583 72 50 0,000 0,14350014 0,15799441 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,14350014 0,15791881 ! membrane fusion GO:0006944 80 50 0,000 0,14350014 0,15784329 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,14350014 0,15776784 ! lipid modification GO:0030258 73 50 0,000 0,14350014 0,15769246 ! proton transport GO:0015992 75 50 0,000 0,14350014 0,15761715 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,14350014 0,15754192 ! hydrogen transport GO:0006818 77 51 0,000 0,14615336 0,16037821 ! muscle fiber development GO:0048747 74 51 0,000 0,14615336 0,16030173 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,14615336 0,16022532 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,14615336 0,16014899 ! adult behavior GO:0030534 80 51 0,000 0,14615336 0,16007273 ! transition metal ion transport GO:0000041 74 52 0,000 0,14879852 0,16289224 ! regulation of cellular component size GO:0032535 74 52 0,000 0,14879852 0,16281474 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,14879852 0,16273732 ! establishment of organelle localization GO:0051656 85 52 0,000 0,14879852 0,16265998 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,15143563 0,16546411 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,15143563 0,16538554 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,15143563 0,16530705 ! kidney development GO:0001822 90 53 0,000 0,15143563 0,16522863 ! single fertilization GO:0007338 59 53 0,000 0,15143563 0,16515028 ! amino acid transport GO:0006865 84 54 0,000 0,15406472 0,16793785 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,15406472 0,1678583 ! regulation of mitosis GO:0007088 84 54 0,000 0,15406472 0,16777882 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,15406472 0,16769942 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,15406472 0,16762009 ! DNA catabolic process GO:0006308 67 54 0,000 0,15406472 0,16754084 ! detection of external stimulus GO:0009581 66 54 0,000 0,15406472 0,16746166 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,15406472 0,16738255 ! exocytosis GO:0006887 74 55 0,000 0,15668582 0,17014985 ! mesoderm development GO:0007498 76 55 0,000 0,15668582 0,17006956 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,15668582 0,16998934 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,15668582 0,16990919 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,15929895 0,17266144 ! carbohydrate transport GO:0008643 74 57 0,000 0,16190413 0,1754025 ! chromosome segregation GO:0007059 83 57 0,000 0,16190413 0,17531991 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,16190413 0,17523741 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,16190413 0,17515498 ! camera-type eye development GO:0043010 88 57 0,000 0,16190413 0,17507264 ! secondary metabolic process GO:0019748 84 57 0,000 0,16190413 0,17499037 ! developmental maturation GO:0021700 75 57 0,000 0,16190413 0,17490817 ! gonad development GO:0008406 79 57 0,000 0,16190413 0,17482606 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,16450138 0,17754725 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,16450138 0,17746397 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,16450138 0,17738077 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,16709074 0,18008843 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,16709074 0,18000408 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,16709074 0,1799198 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,16967222 0,18261399 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,16967222 0,18252858 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,16967222 0,18244325 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,16967222 0,18235799 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,16967222 0,18227282 ! regulation of heart contraction GO:0008016 91 60 0,000 0,16967222 0,18218772 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,16967222 0,18210271 ! fertilization GO:0009566 68 60 0,000 0,16967222 0,18201777 ! meiosis GO:0007126 96 61 0,000 0,17224584 0,18469251 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,17224584 0,18460645 ! urogenital system development GO:0001655 101 61 0,000 0,17224584 0,18452047 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,17224584 0,18443456 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,17224584 0,18434874 ! extracellular matrix organization GO:0030198 103 61 0,000 0,17224584 0,184263 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,17224584 0,18417733 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,17224584 0,18409175 ! amine catabolic process GO:0009310 90 62 0,000 0,17481164 0,18674722 ! neurotransmitter transport GO:0006836 81 62 0,000 0,17481164 0,18666053 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,17481164 0,18657391 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,17481164 0,18648737 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,17481164 0,18640091 ! meiotic cell cycle GO:0051321 97 62 0,000 0,17481164 0,18631454 ! organelle localization GO:0051640 96 62 0,000 0,17481164 0,18622824 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,17736963 0,18886581 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,17736963 0,18877841 ! appendage morphogenesis GO:0035107 93 64 0,000 0,17991983 0,19140408 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,17991983 0,19131559 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,17991983 0,19122718 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,17991983 0,19113885 ! hexose catabolic process GO:0019320 82 64 0,000 0,17991983 0,19105061 ! adaptive immune response GO:0002250 94 64 0,000 0,17991983 0,19096245 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,18246228 0,19357161 ! appendage development GO:0048736 94 65 0,000 0,18246228 0,19348236 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,18246228 0,1933932 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,18246228 0,19330412 ! defense response to bacterium GO:0042742 73 65 0,000 0,18246228 0,19321512 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,18246228 0,19312621 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,18246228 0,19303737 ! activation of immune response GO:0002253 83 65 0,000 0,18246228 0,19294862 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,18499699 0,1955391 ! antigen processing and presentation GO:0019882 96 66 0,000 0,18499699 0,19544928 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,18499699 0,19535954 ! regulation of immune effector process GO:0002697 101 66 0,000 0,18499699 0,19526988 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,18752399 0,19784641 ! acute inflammatory response GO:0002526 92 68 0,000 0,19004329 0,20041246 ! learning or memory GO:0007611 123 68 0,000 0,19004329 0,20032061 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,19004329 0,20022885 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,19004329 0,20013717 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,19004329 0,20004557 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,19004329 0,19995406 ! rhythmic process GO:0048511 105 68 0,000 0,19004329 0,19986263 ! inorganic anion transport GO:0015698 93 68 0,000 0,19004329 0,19977129 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,19255493 0,20231902 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,19255493 0,20222664 ! response to metal ion GO:0010038 103 70 0,000 0,19505892 0,2047629 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,19505892 0,20466949 ! humoral immune response GO:0006959 86 70 0,000 0,19505892 0,20457616 ! eye development GO:0001654 111 70 0,000 0,19505892 0,20448292 ! amine transport GO:0015837 101 70 0,000 0,19505892 0,20438976 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,19755529 0,20691128 ! muscle cell differentiation GO:0042692 104 71 0,000 0,19755529 0,2068171 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,19755529 0,20672301 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,19755529 0,206629 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,19755529 0,20653508 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,19755529 0,20644124 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,20004407 0,20894703 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,20004407 0,20885218 ! regulation of blood pressure GO:0008217 107 73 0,000 0,20252526 0,21134669 ! tube morphogenesis GO:0035239 118 73 0,000 0,20252526 0,21125084 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,20252526 0,21115508 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,20252526 0,2110594 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,2049989 0,21354053 ! digestion GO:0007586 97 74 0,000 0,2049989 0,21344386 ! blood coagulation GO:0007596 116 75 0,000 0,20746502 0,21591382 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,20746502 0,21581616 ! response to nutrient GO:0007584 104 75 0,000 0,20746502 0,2157186 ! regulation of ligase activity GO:0051340 114 75 0,000 0,20746502 0,21562112 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,20746502 0,21552373 ! amine biosynthetic process GO:0009309 97 76 0,000 0,20992362 0,21797938 ! tRNA metabolic process GO:0006399 95 76 0,000 0,20992362 0,21788101 ! response to unfolded protein GO:0006986 99 76 0,000 0,20992362 0,21778273 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,20992362 0,21768455 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,21237473 0,22012703 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,21237473 0,22002788 ! gland development GO:0048732 148 77 0,000 0,21237473 0,21992881 ! sex differentiation GO:0007548 105 77 0,000 0,21237473 0,21982983 ! protein ubiquitination GO:0016567 125 77 0,000 0,21237473 0,21973094 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,21237473 0,21963214 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,21237473 0,21953343 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,21481839 0,2219597 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,21481839 0,22186003 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,21481839 0,22176045 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,2172546 0,22417477 ! cellular respiration GO:0045333 107 79 0,000 0,2172546 0,22407425 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,2172546 0,22397381 ! regulation of lyase activity GO:0051339 133 79 0,000 0,2172546 0,22387346 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,2172546 0,22377321 ! chromatin assembly GO:0031497 102 80 0,000 0,21968339 0,22617359 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,21968339 0,22607239 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,21968339 0,22597128 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,21968339 0,22587027 ! forebrain development GO:0030900 131 80 0,000 0,21968339 0,22576934 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,22210478 0,22815587 ! hemostasis GO:0007599 125 81 0,000 0,22210478 0,22805402 ! mRNA transport GO:0051028 121 81 0,000 0,22210478 0,22795225 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,22210478 0,22785058 ! response to protein stimulus GO:0051789 111 81 0,000 0,22210478 0,227749 ! regulation of neurological system process GO:0031644 122 81 0,000 0,22210478 0,2276475 ! vitamin metabolic process GO:0006766 103 81 0,000 0,22210478 0,2275461 ! detection of stimulus GO:0051606 108 82 0,000 0,2245188 0,22991685 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,22692547 0,23227796 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,22692547 0,23217463 ! regulation of defense response GO:0031347 117 84 0,000 0,2293248 0,23452514 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,2293248 0,23442091 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,2293248 0,23431677 ! sterol metabolic process GO:0016125 120 84 0,000 0,2293248 0,23421272 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,23171683 0,23655069 ! rRNA metabolic process GO:0016072 107 85 0,000 0,23171683 0,23644574 GO:0006364|rRNA processing, ! regulation of membrane potential GO:0042391 128 85 0,000 0,23171683 0,23634089 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,23171683 0,23623613 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,23410156 0,23856163 ! nucleosome organization GO:0034728 114 87 0,000 0,23647904 0,24087767 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,23647904 0,24077104 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,23647904 0,24066451 ! female pregnancy GO:0007565 130 87 0,000 0,23647904 0,24055807 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,23647904 0,24045172 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,23884927 0,24275445 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,23884927 0,24264722 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,23884927 0,24254009 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,23884927 0,24243306 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,23884927 0,24232612 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,24121227 0,24461562 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,24121227 0,24450781 ! regulation of T cell activation GO:0050863 128 89 0,000 0,24121227 0,2444001 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,24356808 0,24667837 ! RNA localization GO:0006403 135 91 0,000 0,24591671 0,24894737 ! ATP metabolic process GO:0046034 137 91 0,000 0,24591671 0,24883785 ! response to virus GO:0009615 122 91 0,000 0,24591671 0,24872842 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,24825818 0,25098629 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,24825818 0,25087601 ! positive regulation of immune response GO:0050778 121 92 0,000 0,24825818 0,25076583 ! DNA recombination GO:0006310 146 92 0,000 0,24825818 0,25065575 ! sulfur metabolic process GO:0006790 118 92 0,000 0,24825818 0,25054577 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,25059251 0,25279069 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,25059251 0,25267987 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,25059251 0,25256914 ! electron transport chain GO:0022900 123 94 0,000 0,25291973 0,25480306 ! carboxylic acid transport GO:0046942 147 95 0,000 0,25523985 0,25702787 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,25755291 0,25924363 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,25755291 0,25913022 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,25755291 0,25901691 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,25755291 0,25890371 ! protein maturation GO:0051604 129 96 0,000 0,25755291 0,2587906 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,25985891 0,26099366 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,25985891 0,26087974 ! calcium ion transport GO:0006816 167 99 0,000 0,26444984 0,26537288 ! extracellular structure organization GO:0043062 156 99 0,000 0,26444984 0,26525715 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,26444984 0,26514151 ! regulation of translation GO:0006417 151 100 0,000 0,26673482 0,26731594 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,26673482 0,26719951 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,26673482 0,26708319 ! divalent metal ion transport GO:0070838 171 100 0,000 0,26673482 0,26696696 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,26673482 0,26685084 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,26673482 0,26673482