pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6129-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 3,24E-10 7,796E-07 ! pigmentation GO:0043473 100 46 5,000 4,164E-09 5,009E-06 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 1,346E-08 1,079E-05 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 3,159E-08 1,9E-05 ! spindle organization GO:0007051 46 32 4,000 3,39E-08 1,631E-05 ! cell killing GO:0001906 29 15 3,000 8,653E-08 3,47E-05 ! L-serine biosynthetic process GO:0006564 6 5 2,000 2,319E-07 7,969E-05 ! L-serine metabolic process GO:0006563 18 10 2,000 2,753E-06 8,281E-04 ! protein sumoylation GO:0016925 15 10 2,000 2,753E-06 7,361E-04 ! polyamine metabolic process GO:0006595 17 12 2,000 5,027E-06 1,209E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 6,521E-06 1,426E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 8,282E-06 1,661E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 8,84E-06 1,636E-03 ! pigmentation during development GO:0048066 41 19 2,000 2,182E-05 3,75E-03 ! cellular pigmentation GO:0033059 36 19 2,000 2,182E-05 3,5E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 2,182E-05 3,281E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,562E-05 3,625E-03 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 3,616E-05 4,833E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 4,51E-05 5,711E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 5,769E-05 6,941E-03 GO:0045936|negative regulation of phosphate metabolic process, ! leukocyte mediated immunity GO:0002443 128 74 3,000 6,405E-05 7,339E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 6,477E-05 7,083E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 8,203E-05 8,581E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 8,203E-05 8,223E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 8,203E-05 7,894E-03 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 9,871E-05 9,134E-03 ! amine biosynthetic process GO:0009309 138 86 3,000 1,151E-04 0,01026003 ! establishment of spindle localization GO:0051293 12 6 1,000 1,228E-04 0,01055278 GO:0051653|spindle localization, ! response to exogenous dsRNA GO:0043330 10 6 1,000 1,228E-04 0,01018889 ! mitotic sister chromatid segregation GO:0000070 57 36 2,000 1,552E-04 0,01244395 ! sister chromatid segregation GO:0000819 58 37 2,000 1,685E-04 0,01307779 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 1,716E-04 0,01290285 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,716E-04 0,01251185 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 1,716E-04 0,01214386 ! aspartate family amino acid catabolic process GO:0009068 9 7 1,000 1,716E-04 0,01179689 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2,284E-04 0,01526352 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 2,284E-04 0,01485099 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,284E-04 0,01446017 ! melanosome transport GO:0032402 13 8 1,000 2,284E-04 0,0140894 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,284E-04 0,01373717 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 2,284E-04 0,01340211 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,464E-04 0,01411363 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,931E-04 0,01639896 ! microtubule bundle formation GO:0001578 21 9 1,000 2,931E-04 0,01602625 ! middle ear morphogenesis GO:0042474 14 9 1,000 2,931E-04 0,01567011 ! motor axon guidance GO:0008045 16 9 1,000 2,931E-04 0,01532946 ! establishment of melanosome localization GO:0032401 14 9 1,000 2,931E-04 0,0150033 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 2,931E-04 0,01469073 ! pigment granule transport GO:0051904 17 9 1,000 2,931E-04 0,01439092 ! regulation of telomere maintenance GO:0032204 14 9 1,000 2,931E-04 0,0141031 ! pyrimidine base metabolic process GO:0006206 17 9 1,000 2,931E-04 0,01382657 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,657E-04 0,016919 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,657E-04 0,01659977 ! polyamine biosynthetic process GO:0006596 12 10 1,000 3,657E-04 0,01629237 ! response to dsRNA GO:0043331 20 10 1,000 3,657E-04 0,01599614 ! melanosome localization GO:0032400 16 10 1,000 3,657E-04 0,0157105 ! apical protein localization GO:0045176 15 10 1,000 3,657E-04 0,01543487 ! establishment of pigment granule localization GO:0051905 18 10 1,000 3,657E-04 0,01516875 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,666E-04 0,01494889 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 4,137E-04 0,01658863 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 4,386E-04 0,01730041 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,386E-04 0,01702137 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! detection of mechanical stimulus GO:0050982 22 11 1,000 4,461E-04 0,01703613 ! melanocyte differentiation GO:0030318 21 11 1,000 4,461E-04 0,01676994 GO:0050931|pigment cell differentiation, ! pigment granule localization GO:0051875 20 11 1,000 4,461E-04 0,01651194 ! DNA methylation GO:0006306 19 11 1,000 4,461E-04 0,01626176 GO:0006305|DNA alkylation, ! T cell receptor signaling pathway GO:0050852 23 11 1,000 4,461E-04 0,01601905 ! regulation of angiogenesis GO:0045765 114 52 2,000 4,645E-04 0,01643539 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,343E-04 0,01863062 ! positive regulation of cell growth GO:0030307 22 12 1,000 5,343E-04 0,01836447 ! focal adhesion formation GO:0048041 35 12 1,000 5,343E-04 0,01810581 ! asymmetric protein localization GO:0008105 20 12 1,000 5,343E-04 0,01785434 ! digestive tract morphogenesis GO:0048546 26 12 1,000 5,343E-04 0,01760976 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 5,343E-04 0,01737179 GO:0042130|negative regulation of T cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 6,086E-04 0,0195249 ! endocrine pancreas development GO:0031018 22 13 1,000 6,303E-04 0,01995249 ! Golgi organization GO:0007030 24 13 1,000 6,303E-04 0,01969337 ! chromatin silencing GO:0006342 26 13 1,000 6,303E-04 0,01944089 ! establishment of organelle localization GO:0051656 109 59 2,000 6,734E-04 0,02050901 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 7,339E-04 0,0220725 ! negative regulation of caspase activity GO:0043154 22 14 1,000 7,339E-04 0,0218 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 7,339E-04 0,02153414 ! regulation of homeostatic process GO:0032844 134 62 2,000 7,785E-04 0,02256842 ! positive regulation of cell size GO:0045793 27 15 1,000 8,452E-04 0,02420997 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 9,642E-04 0,02729171 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 9,642E-04 0,02697437 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 9,759E-04 0,02699006 ! chromosome segregation GO:0007059 113 67 2,000 9,759E-04 0,02668335 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,019E-03 0,02754392 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,091E-03 0,02915744 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,091E-03 0,02883702 ! heart looping GO:0001947 30 17 1,000 1,091E-03 0,02852358 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 1,091E-03 0,02821687 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,091E-03 0,02791669 ! nucleobase metabolic process GO:0009112 37 17 1,000 1,091E-03 0,02762283 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,091E-03 0,0273351 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 1,091E-03 0,02705329 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,091E-03 0,02677724 ! regulation of caspase activity GO:0043281 122 72 2,000 1,202E-03 0,02922348 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,202E-03 0,02893124 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,225E-03 0,02917478 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 1,302E-03 0,03070158 ! organelle localization GO:0051640 136 74 2,000 1,302E-03 0,03040351 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,366E-03 0,03160713 ! skin development GO:0043588 36 19 1,000 1,366E-03 0,03130611 ! mitotic chromosome condensation GO:0007076 34 19 1,000 1,366E-03 0,03101077 ! actin filament bundle formation GO:0051017 42 19 1,000 1,366E-03 0,03072095 ! neuromuscular junction development GO:0007528 34 19 1,000 1,366E-03 0,0304365 ! response to lipopolysaccharide GO:0032496 30 19 1,000 1,366E-03 0,03015727 ! negative regulation of organelle organization GO:0010639 161 78 2,000 1,515E-03 0,03313391 ! response to alkaloid GO:0043279 38 20 1,000 1,515E-03 0,03284263 ! pancreas development GO:0031016 35 20 1,000 1,515E-03 0,03254939 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,515E-03 0,03226135 ! negative regulation of translation GO:0017148 29 20 1,000 1,515E-03 0,03197835 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,571E-03 0,03287603 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 1,672E-03 0,03467 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 1,672E-03 0,03437367 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 1,672E-03 0,03408237 ! DNA modification GO:0006304 34 21 1,000 1,672E-03 0,03379596 ! gut development GO:0048565 39 21 1,000 1,672E-03 0,03351433 ! response to drug GO:0042493 143 82 2,000 1,749E-03 0,03477477 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,835E-03 0,03619345 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 1,835E-03 0,03589919 ! apoptotic nuclear changes GO:0030262 32 22 1,000 1,835E-03 0,03560968 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,835E-03 0,0353248 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 1,835E-03 0,03504445 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,835E-03 0,03476851 ! mitochondrion organization GO:0007005 148 86 2,000 2,004E-03 0,03767416 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,006E-03 0,03741917 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 2,006E-03 0,03713133 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 2,006E-03 0,03684788 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 2,006E-03 0,03656873 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,185E-03 0,03951904 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 2,185E-03 0,03922412 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 2,185E-03 0,03893358 ! lymphocyte proliferation GO:0046651 48 24 1,000 2,185E-03 0,0386473 ! aspartate family amino acid metabolic process GO:0009066 42 24 1,000 2,185E-03 0,0383652 ! protein tetramerization GO:0051262 52 24 1,000 2,185E-03 0,03808719 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,37E-03 0,04102431 ! myelination GO:0042552 45 25 1,000 2,37E-03 0,04073128 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,37E-03 0,0404424 ! chromosome condensation GO:0030261 45 25 1,000 2,37E-03 0,0401576 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 2,505E-03 0,04214347 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 2,563E-03 0,04281951 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,563E-03 0,0425242 ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,563E-03 0,04223294 ! positive regulation of nuclear division GO:0051785 40 26 1,000 2,563E-03 0,04194564 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 52 26 1,000 2,563E-03 0,04166223 GO:0032943|mononuclear cell proliferation, ! biogenic amine metabolic process GO:0006576 155 94 2,000 2,582E-03 0,04169333 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,763E-03 0,04431216 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,763E-03 0,0440187 ! fat cell differentiation GO:0045444 50 27 1,000 2,763E-03 0,0437291 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,763E-03 0,04344329 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 2,822E-03 0,04409618 ! dendrite development GO:0016358 59 28 1,000 2,97E-03 0,04609497 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,97E-03 0,04579949 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,97E-03 0,04550777 ! cell cycle arrest GO:0007050 213 100 2,000 3,076E-03 0,04684477 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 3,184E-03 0,04817357 ! immune response-activating signal transduction GO:0002757 47 29 1,000 3,184E-03 0,04787249 GO:0002764|immune response-regulating signal transduction, ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,184E-03 0,04757514 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,184E-03 0,04728147 ! cell junction assembly GO:0034329 78 30 1,000 3,405E-03 0,05025373 ! determination of left/right symmetry GO:0007368 47 30 1,000 3,405E-03 0,04994731 ! ensheathment of neurons GO:0007272 57 30 1,000 3,405E-03 0,0496446 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,405E-03 0,04934553 ! regulation of B cell activation GO:0050864 50 30 1,000 3,405E-03 0,04905005 ! determination of bilateral symmetry GO:0009855 49 31 1,000 3,633E-03 0,05202322 GO:0009799|determination of symmetry, ! iron ion homeostasis GO:0055072 54 31 1,000 3,633E-03 0,05171539 ! response to mechanical stimulus GO:0009612 57 32 1,000 3,867E-03 0,05473604 ! peripheral nervous system development GO:0007422 64 32 1,000 3,867E-03 0,05441595 ! gene silencing GO:0016458 65 32 1,000 3,867E-03 0,05409958 ! establishment of vesicle localization GO:0051650 61 33 1,000 4,109E-03 0,05714993 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 4,358E-03 0,06025997 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 4,613E-03 0,06342812 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,613E-03 0,06306773 ! vesicle localization GO:0051648 64 35 1,000 4,613E-03 0,06271142 ! cell junction organization GO:0034330 86 36 1,000 4,876E-03 0,06590392 ! negative regulation of cell activation GO:0050866 65 36 1,000 4,876E-03 0,06553574 ! meiosis I GO:0007127 65 37 1,000 5,145E-03 0,06876704 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 5,145E-03 0,06838712 ! nucleus organization GO:0006997 67 38 1,000 5,42E-03 0,07165569 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,42E-03 0,07126413 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 5,703E-03 0,07456851 ! ear morphogenesis GO:0042471 60 39 1,000 5,703E-03 0,07416543 ! regulation of action potential in neuron GO:0019228 73 39 1,000 5,703E-03 0,07376669 ! cytokinesis GO:0000910 72 40 1,000 5,992E-03 0,07708973 ! regulation of T cell proliferation GO:0042129 71 41 1,000 6,287E-03 0,08046151 ! keratinocyte differentiation GO:0030216 62 41 1,000 6,287E-03 0,08003579 ! regulation of T cell differentiation GO:0045580 70 41 1,000 6,287E-03 0,07961455 ! response to reactive oxygen species GO:0000302 67 42 1,000 6,589E-03 0,08300243 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 6,589E-03 0,08257012 ! epithelial cell differentiation GO:0030855 79 43 1,000 6,898E-03 0,08598852 ! glucose transport GO:0015758 65 43 1,000 6,898E-03 0,08554528 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 6,898E-03 0,08510658 ! hexose transport GO:0008645 67 44 1,000 7,213E-03 0,08853893 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 7,213E-03 0,08808949 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 7,534E-03 0,09155004 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 7,862E-03 0,0950529 ! epidermal cell differentiation GO:0009913 68 46 1,000 7,862E-03 0,09457763 ! response to insulin stimulus GO:0032868 95 46 1,000 7,862E-03 0,0941071 ! methylation GO:0032259 90 47 1,000 8,196E-03 0,09762075 ! positive regulation of cell cycle GO:0045787 89 48 1,000 8,536E-03 0,10117443 ! cellular component disassembly GO:0022411 86 48 1,000 8,536E-03 0,10067847 ! activation of caspase activity GO:0006919 84 48 1,000 8,536E-03 0,10018736 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 8,536E-03 0,09970101 ! regulation of action potential GO:0001508 95 49 1,000 8,883E-03 0,10324873 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 8,883E-03 0,10275234 ! endocrine system development GO:0035270 104 49 1,000 8,883E-03 0,10226071 ! detection of abiotic stimulus GO:0009582 74 49 1,000 8,883E-03 0,10177375 ! negative regulation of immune system process GO:0002683 95 50 1,000 9,236E-03 0,10531534 ! chromatin remodeling GO:0006338 109 51 1,000 9,595E-03 0,10889369 ! regulation of cell shape GO:0008360 125 51 1,000 9,595E-03 0,10838246 ! positive regulation of growth GO:0045927 90 52 1,000 9,96E-03 0,11198214 ! covalent chromatin modification GO:0016569 101 52 1,000 9,96E-03 0,11146129 ! synapse organization GO:0050808 85 52 1,000 9,96E-03 0,11094527 ! response to UV GO:0009411 104 53 1,000 0,0103315 0,1145511 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,0107089 0,11819085 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,0107089 0,11765117 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01109233 0,12130973 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 97 55 1,000 0,01109233 0,12076081 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01148175 0,12443739 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01148175 0,12387938 ! muscle fiber development GO:0048747 112 57 1,000 0,01187714 0,12757322 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01268564 0,13565182 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01268564 0,13505159 ! DNA catabolic process GO:0006308 86 59 1,000 0,01268564 0,13445665 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,01309869 0,13822563 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01309869 0,13762202 ! kidney development GO:0001822 122 60 1,000 0,01309869 0,13702367 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01351754 0,14079313 ! ear development GO:0043583 103 62 1,000 0,01394218 0,14459 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01436141 0,14829852 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01436141 0,14766476 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01436141 0,1470364 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01436141 0,14641337 ! neuron fate determination GO:0048664 7 5 0,000 0,01436141 0,14579559 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01436141 0,145183 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01436141 0,14457554 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01436141 0,14397314 ! polyol transport GO:0015791 12 5 0,000 0,01436141 0,14337574 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01436141 0,14278328 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01436141 0,1421957 ! response to superoxide GO:0000303 10 5 0,000 0,01436141 0,14161293 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01436141 0,14103492 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01436141 0,1404616 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01436141 0,13989293 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01436141 0,13932885 ! female meiosis GO:0007143 7 5 0,000 0,01436141 0,13876929 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01436141 0,13821422 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01436141 0,13766356 ! cobalt ion transport GO:0006824 11 5 0,000 0,01436141 0,13711728 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01436141 0,13657531 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01436141 0,13603762 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01436141 0,13550413 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01436141 0,13497482 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01436141 0,13444963 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01436141 0,13392851 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01436141 0,13341141 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01436141 0,13289829 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01436141 0,1323891 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01436141 0,1318838 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01436141 0,13138234 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01436141 0,13088468 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01436141 0,13039077 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01436141 0,12990058 ! negative chemotaxis GO:0050919 14 5 0,000 0,01436141 0,12941406 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01436141 0,12893117 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01436141 0,12845187 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01436141 0,12797613 ! behavioral response to pain GO:0048266 9 5 0,000 0,01436141 0,12750389 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01436141 0,12703513 ! Notch receptor processing GO:0007220 8 5 0,000 0,01436141 0,1265698 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01436141 0,12610786 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01436141 0,12564929 ! micturition GO:0060073 9 5 0,000 0,01436141 0,12519404 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01436141 0,12474207 ! copulation GO:0007620 9 5 0,000 0,01436141 0,12429336 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01436141 0,12384787 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01436141 0,12340555 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01436141 0,12296639 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01436141 0,12253033 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01436141 0,12209737 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01436141 0,12166744 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01436141 0,12124054 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01436141 0,12081662 ! grooming behavior GO:0007625 6 5 0,000 0,01436141 0,12039566 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01436141 0,11997762 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01436141 0,11956247 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01436141 0,11915019 ! response to protozoan GO:0001562 10 5 0,000 0,01436141 0,11874074 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01436141 0,11833409 ! lymph vessel development GO:0001945 10 5 0,000 0,01436141 0,11793022 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01436141 0,1175291 ! endochondral ossification GO:0001958 16 5 0,000 0,01436141 0,11713069 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01436141 0,11673498 ! parathyroid gland development GO:0060017 13 5 0,000 0,01436141 0,11634193 ! anagen GO:0042640 6 5 0,000 0,01436141 0,11595152 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01436141 0,11556373 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01436141 0,11517851 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01436141 0,11479586 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01436141 0,11441574 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01436141 0,11403813 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01436141 0,11366301 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01436141 0,11329034 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01436141 0,11292011 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01436141 0,11255229 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01436141 0,11218686 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01436141 0,1118238 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01436141 0,11146308 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01436141 0,11110468 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01436141 0,11074857 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01436141 0,11039474 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01436141 0,11004317 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01436141 0,10969382 ! histidine catabolic process GO:0006548 6 5 0,000 0,01436141 0,10934669 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01436141 0,10900175 ! microvillus organization GO:0032528 7 5 0,000 0,01436141 0,10865898 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01436141 0,10831835 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01436141 0,10797986 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01436141 0,10764347 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01436141 0,10730918 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01436141 0,10697695 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01436141 0,10664677 ! polyol catabolic process GO:0046174 7 5 0,000 0,01436141 0,10631863 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01436141 0,1059925 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01436141 0,10566836 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01436141 0,1053462 ! muscle cell migration GO:0014812 8 5 0,000 0,01436141 0,105026 ! mitochondrial fission GO:0000266 8 5 0,000 0,01436141 0,10470774 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01436141 0,1043914 ! mRNA transcription GO:0009299 9 5 0,000 0,01436141 0,10407697 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01436141 0,10376443 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01436141 0,10345376 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01436141 0,10314494 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01436141 0,10283796 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01436141 0,1025328 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01436141 0,10222945 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01436141 0,10192789 ! response to food GO:0032094 6 5 0,000 0,01436141 0,1016281 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01436141 0,10133007 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01436141 0,10103378 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01436141 0,10073923 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01436141 0,10044638 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01436141 0,10015523 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01436141 0,09986576 ! forebrain neuron development GO:0021884 13 5 0,000 0,01436141 0,09957797 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01436141 0,09929182 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01436141 0,09900732 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01436141 0,09872444 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01436141 0,09844317 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01436141 0,09816351 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01436141 0,09788542 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01436141 0,09760891 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01436141 0,09733396 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01436141 0,09706055 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01436141 0,09678867 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01436141 0,09651831 ! basic amino acid transport GO:0015802 11 5 0,000 0,01436141 0,09624946 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01436141 0,0959821 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01436141 0,09571622 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01436141 0,09545181 ! depyrimidination GO:0045008 10 5 0,000 0,01436141 0,09518885 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01436141 0,09492735 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01436141 0,09466727 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01436141 0,09440862 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01436141 0,09415137 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01436141 0,09389553 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01436141 0,09364107 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01436141 0,09338798 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01436141 0,09313627 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01436141 0,0928859 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01436141 0,09263687 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01436141 0,09238918 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01436141 0,09214281 ! response to arsenic GO:0046685 10 5 0,000 0,01436141 0,09189775 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01436141 0,09165399 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01436141 0,09141152 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01436141 0,09117033 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01436141 0,09093041 ! response to cadmium ion GO:0046686 7 5 0,000 0,01436141 0,09069174 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01436141 0,09045433 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01436141 0,09021816 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01436141 0,08998321 ! decidualization GO:0046697 11 5 0,000 0,01436141 0,08974949 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01436141 0,08951698 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01436141 0,08928567 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01436141 0,08905555 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01436141 0,08882662 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01436141 0,08859886 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01436141 0,08837226 ! neural tube patterning GO:0021532 7 5 0,000 0,01436141 0,08814682 ! embryonic cleavage GO:0040016 6 5 0,000 0,01436141 0,08792253 ! peroxisome fission GO:0016559 5 5 0,000 0,01436141 0,08769938 ! histone demethylation GO:0016577 10 5 0,000 0,01436141 0,08747735 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01436141 0,08725645 ! mitotic recombination GO:0006312 9 5 0,000 0,01436141 0,08703666 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01436141 0,08681798 ! metaphase plate congression GO:0051310 7 5 0,000 0,01436141 0,08660039 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01436141 0,08638389 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01436141 0,08616846 ! enteric nervous system development GO:0048484 8 5 0,000 0,01436141 0,08595412 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01436141 0,08574083 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01436141 0,0855286 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01436141 0,08531742 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01436141 0,08510728 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01436141 0,08489817 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01436141 0,08469008 ! plasminogen activation GO:0031639 5 5 0,000 0,01436141 0,08448302 ! B cell homeostasis GO:0001782 13 5 0,000 0,01436141 0,08427696 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01436141 0,08407191 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01436141 0,08386785 ! metaphase GO:0051323 8 5 0,000 0,01436141 0,08366478 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01436141 0,08346269 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01436141 0,08326158 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01436141 0,08306143 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01436141 0,08286224 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01436141 0,08266401 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01436141 0,08246672 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01436141 0,08227037 ! response to redox state GO:0051775 5 5 0,000 0,01436141 0,08207495 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01436141 0,08188046 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01436141 0,08168689 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01436141 0,08149423 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01436141 0,08130248 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01436141 0,08111163 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01436141 0,08092167 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01436141 0,0807326 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01436141 0,08054442 ! striatum development GO:0021756 9 5 0,000 0,01436141 0,0803571 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01436141 0,08017066 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01436141 0,07998508 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01436141 0,07980036 ! glial cell migration GO:0008347 11 5 0,000 0,01436141 0,07961648 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01436141 0,07943346 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01436141 0,07925127 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01436141 0,07906992 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01436141 0,07888939 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01436141 0,07870969 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01436141 0,07853081 ! neuroprotection GO:0043526 6 5 0,000 0,01436141 0,07835273 ! neural plate development GO:0001840 8 5 0,000 0,01436141 0,07817546 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01436141 0,07799899 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01436141 0,07782332 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01436141 0,07764844 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01436141 0,07747434 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01436141 0,07730102 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01436141 0,07712847 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01436141 0,07695669 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01436141 0,07678568 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01436141 0,07661542 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01436141 0,07644592 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01436141 0,07627716 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01436141 0,07610915 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01436141 0,07594188 ! drug metabolic process GO:0017144 6 5 0,000 0,01436141 0,07577534 ! stem cell division GO:0017145 11 5 0,000 0,01436141 0,07560953 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01436141 0,07544444 ! organ regeneration GO:0031100 7 5 0,000 0,01436141 0,07528007 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01436141 0,07511642 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01436141 0,07495348 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01436141 0,07479124 ! regulation of mitosis GO:0007088 105 63 1,000 0,01437255 0,0746876 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,01437255 0,07452664 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,01437255 0,07436636 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,01525038 0,07873908 ! actin filament organization GO:0007015 148 66 1,000 0,01569776 0,08087539 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01615074 0,08303136 ! activation of immune response GO:0002253 105 67 1,000 0,01615074 0,08285432 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01707335 0,08740101 ! urogenital system development GO:0001655 137 69 1,000 0,01707335 0,08721544 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01720913 0,08772282 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01720913 0,08753736 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01720913 0,08735268 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01720913 0,08716878 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01720913 0,08698565 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01720913 0,08680329 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01720913 0,08662169 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01720913 0,08644086 ! sleep GO:0030431 13 6 0,000 0,01720913 0,08626077 ! response to oxygen radical GO:0000305 11 6 0,000 0,01720913 0,08608143 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01720913 0,08590284 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01720913 0,08572499 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01720913 0,08554787 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01720913 0,08537148 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01720913 0,08519582 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01720913 0,08502088 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01720913 0,08484666 ! forebrain regionalization GO:0021871 8 6 0,000 0,01720913 0,08467315 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01720913 0,08450035 ! male meiosis GO:0007140 7 6 0,000 0,01720913 0,08432825 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01720913 0,08415685 ! response to zinc ion GO:0010043 9 6 0,000 0,01720913 0,08398615 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01720913 0,08381613 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01720913 0,08364681 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01720913 0,08347816 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01720913 0,0833102 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01720913 0,08314291 ! malate metabolic process GO:0006108 11 6 0,000 0,01720913 0,08297629 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01720913 0,08281034 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01720913 0,08264505 ! protein refolding GO:0042026 15 6 0,000 0,01720913 0,08248042 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01720913 0,08231644 ! opsonization GO:0008228 8 6 0,000 0,01720913 0,08215311 ! mating behavior GO:0007617 7 6 0,000 0,01720913 0,08199044 ! neuron remodeling GO:0016322 15 6 0,000 0,01720913 0,0818284 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01720913 0,081667 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01720913 0,08150624 ! equilibrioception GO:0050957 14 6 0,000 0,01720913 0,08134611 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01720913 0,08118661 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01720913 0,08102773 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01720913 0,08086947 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01720913 0,08071183 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01720913 0,0805548 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01720913 0,08039839 ! toxin metabolic process GO:0009404 11 6 0,000 0,01720913 0,08024258 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01720913 0,08008737 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01720913 0,07993276 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01720913 0,07977875 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01720913 0,07962533 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01720913 0,07947249 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01720913 0,07932025 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01720913 0,07916858 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01720913 0,0790175 ! thymic T cell selection GO:0045061 12 6 0,000 0,01720913 0,07886699 ! protein lipoylation GO:0009249 10 6 0,000 0,01720913 0,07871705 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01720913 0,07856768 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01720913 0,07841888 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01720913 0,07827064 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01720913 0,07812296 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01720913 0,07797584 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01720913 0,07782927 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01720913 0,07768325 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01720913 0,07753777 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01720913 0,07739284 ! hyperosmotic response GO:0006972 9 6 0,000 0,01720913 0,07724845 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01720913 0,0771046 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01720913 0,07696128 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01720913 0,0768185 ! urea metabolic process GO:0019627 7 6 0,000 0,01720913 0,07667624 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01720913 0,07653451 ! neutrophil activation GO:0042119 8 6 0,000 0,01720913 0,0763933 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01720913 0,07625261 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01720913 0,07611244 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01720913 0,07597279 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01720913 0,07583364 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01720913 0,07569501 ! neuron apoptosis GO:0051402 9 6 0,000 0,01720913 0,07555688 ! nucleoside salvage GO:0043174 9 6 0,000 0,01720913 0,07541925 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01720913 0,07528213 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01720913 0,0751455 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01720913 0,07500937 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01720913 0,07487372 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01720913 0,07473857 ! carnitine transport GO:0015879 10 6 0,000 0,01720913 0,07460391 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01720913 0,07446973 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01720913 0,07433603 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01720913 0,07420281 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01720913 0,07407007 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01720913 0,0739378 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01720913 0,07380601 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01720913 0,07367468 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01720913 0,07354382 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01720913 0,07341342 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01720913 0,07328349 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01720913 0,07315401 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01720913 0,07302499 ! neural nucleus development GO:0048857 14 6 0,000 0,01720913 0,07289643 ! response to UV-C GO:0010225 11 6 0,000 0,01720913 0,07276831 ! astrocyte development GO:0014002 15 6 0,000 0,01720913 0,07264065 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01720913 0,07251343 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01720913 0,07238666 ! interaction with symbiont GO:0051702 13 6 0,000 0,01720913 0,07226033 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01720913 0,07213444 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01720913 0,07200899 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01720913 0,07188398 ! response to copper ion GO:0046688 10 6 0,000 0,01720913 0,07175939 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01720913 0,07163524 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01720913 0,07151152 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01720913 0,07138822 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01720913 0,07126535 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01720913 0,0711429 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01720913 0,07102087 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01720913 0,07089926 ! hair follicle maturation GO:0048820 7 6 0,000 0,01720913 0,07077807 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01720913 0,07065729 ! Schwann cell development GO:0014044 15 6 0,000 0,01720913 0,07053692 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01720913 0,07041696 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01720913 0,0702974 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01720913 0,07017825 ! subpallium development GO:0021544 10 6 0,000 0,01720913 0,07005951 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01720913 0,06994117 ! histone ubiquitination GO:0016574 8 6 0,000 0,01720913 0,06982322 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01720913 0,06970567 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01720913 0,06958852 ! G2 phase GO:0051319 16 6 0,000 0,01720913 0,06947176 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01720913 0,06935539 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01720913 0,06923941 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01720913 0,06912382 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01720913 0,06900862 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01720913 0,06889379 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01720913 0,06877935 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01720913 0,06866529 ! receptor internalization GO:0031623 10 6 0,000 0,01720913 0,06855161 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01720913 0,0684383 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01720913 0,06832536 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01720913 0,0682128 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01720913 0,06810061 ! protein deubiquitination GO:0016579 14 6 0,000 0,01720913 0,06798878 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01720913 0,06787733 ! protein destabilization GO:0031648 9 6 0,000 0,01720913 0,06776624 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01720913 0,06765551 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01720913 0,06754514 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01720913 0,06743513 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01720913 0,06732548 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01720913 0,06721618 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01720913 0,06710724 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01720913 0,06699866 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01720913 0,06689042 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01720913 0,06678253 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01720913 0,06667499 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01720913 0,0665678 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01720913 0,06646095 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01720913 0,06635444 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01720913 0,06624827 ! catecholamine transport GO:0051937 9 6 0,000 0,01720913 0,06614244 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01720913 0,06603695 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01720913 0,0659318 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01720913 0,06582698 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01720913 0,06572249 ! maternal placenta development GO:0001893 12 6 0,000 0,01720913 0,06561834 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01720913 0,06551451 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01720913 0,06541101 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01720913 0,06530784 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01720913 0,06520499 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01720913 0,06510247 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01720913 0,06500027 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01720913 0,06489839 ! amine catabolic process GO:0009310 117 71 1,000 0,01801793 0,06784215 ! carbohydrate transport GO:0008643 110 72 1,000 0,01849837 0,06954231 ! axon guidance GO:0007411 139 73 1,000 0,0189842 0,07125739 ! meiosis GO:0007126 121 74 1,000 0,01947538 0,07298719 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01997189 0,07473151 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01997189 0,07461547 ! meiotic cell cycle GO:0051321 122 75 1,000 0,01997189 0,07449979 ! tRNA transcription GO:0009304 14 7 0,000 0,02004872 0,07467061 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02004872 0,0745552 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02004872 0,07444015 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02004872 0,07432545 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02004872 0,0742111 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02004872 0,07409711 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02004872 0,07398346 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02004872 0,07387016 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02004872 0,07375721 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02004872 0,0736446 ! prostate gland development GO:0030850 13 7 0,000 0,02004872 0,07353234 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02004872 0,07342042 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02004872 0,07330884 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02004872 0,0731976 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02004872 0,07308669 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02004872 0,07297612 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02004872 0,07286589 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02004872 0,07275598 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02004872 0,07264641 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02004872 0,07253717 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02004872 0,07242825 ! glycolipid transport GO:0046836 10 7 0,000 0,02004872 0,07231966 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02004872 0,0722114 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02004872 0,07210346 ! neuron adhesion GO:0007158 12 7 0,000 0,02004872 0,07199584 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02004872 0,07188855 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02004872 0,07178157 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02004872 0,07167491 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02004872 0,07156857 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02004872 0,07146254 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02004872 0,07135683 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02004872 0,07125143 ! mRNA stabilization GO:0048255 18 7 0,000 0,02004872 0,07114634 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02004872 0,07104156 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02004872 0,07093708 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02004872 0,07083292 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02004872 0,07072906 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02004872 0,0706255 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02004872 0,07052225 ! lipoprotein transport GO:0042953 14 7 0,000 0,02004872 0,07041929 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02004872 0,07031664 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02004872 0,07021429 ! rhythmic behavior GO:0007622 15 7 0,000 0,02004872 0,07011223 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02004872 0,07001047 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02004872 0,06990901 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02004872 0,06980784 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02004872 0,06970696 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02004872 0,06960637 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02004872 0,06950608 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02004872 0,06940607 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02004872 0,06930635 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02004872 0,06920691 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02004872 0,06910776 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02004872 0,06900889 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02004872 0,06891031 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02004872 0,06881201 ! spinal cord patterning GO:0021511 13 7 0,000 0,02004872 0,06871398 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02004872 0,06861624 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02004872 0,06851877 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02004872 0,06842158 ! adrenal gland development GO:0030325 17 7 0,000 0,02004872 0,06832467 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02004872 0,06822803 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02004872 0,06813166 ! ovulation GO:0030728 9 7 0,000 0,02004872 0,06803557 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02004872 0,06793974 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02004872 0,06784419 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02004872 0,0677489 ! microtubule nucleation GO:0007020 20 7 0,000 0,02004872 0,06765388 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02004872 0,06755913 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02004872 0,06746464 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02004872 0,06737041 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02004872 0,06727645 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02004872 0,06718275 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02004872 0,06708931 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02004872 0,06699613 ! galactose metabolic process GO:0006012 13 7 0,000 0,02004872 0,06690321 ! vesicle fusion GO:0006906 17 7 0,000 0,02004872 0,06681055 ! response to dietary excess GO:0002021 8 7 0,000 0,02004872 0,06671814 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02004872 0,06662599 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02004872 0,06653409 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02004872 0,06644245 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02004872 0,06635105 ! organ growth GO:0035265 15 7 0,000 0,02004872 0,06625991 ! purine salvage GO:0043101 10 7 0,000 0,02004872 0,06616902 ! nucleoside transport GO:0015858 8 7 0,000 0,02004872 0,06607838 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02004872 0,06598798 ! parturition GO:0007567 14 7 0,000 0,02004872 0,06589784 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02004872 0,06580793 ! rRNA modification GO:0000154 14 7 0,000 0,02004872 0,06571828 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02004872 0,06562887 ! spindle checkpoint GO:0031577 15 7 0,000 0,02004872 0,0655397 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02004872 0,06545077 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02004872 0,06536208 ! macrophage differentiation GO:0030225 11 7 0,000 0,02004872 0,06527363 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02004872 0,06518543 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02004872 0,06509746 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02004872 0,06500973 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02004872 0,06492223 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02004872 0,06483497 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02004872 0,06474794 ! fibrinolysis GO:0042730 10 7 0,000 0,02004872 0,06466115 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02004872 0,06457459 ! eating behavior GO:0042755 7 7 0,000 0,02004872 0,06448826 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02004872 0,06440216 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02004872 0,06431629 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02004872 0,06423065 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02004872 0,06414523 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02004872 0,06406005 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02004872 0,06397509 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02004872 0,06389035 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02004872 0,06380584 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02004872 0,06372155 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02004872 0,06363749 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02004872 0,06355364 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02004872 0,06347002 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02004872 0,06338662 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02004872 0,06330343 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02004872 0,06322047 ! regulation of meiosis GO:0040020 12 7 0,000 0,02004872 0,06313772 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02004872 0,06305518 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02004872 0,06297287 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02004872 0,06289076 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02004872 0,06280888 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02004872 0,0627272 ! transcription termination GO:0006353 13 7 0,000 0,02004872 0,06264574 ! response to tumor cell GO:0002347 13 7 0,000 0,02004872 0,06256448 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02004872 0,06248344 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02004872 0,06240261 ! anaphase GO:0051322 17 7 0,000 0,02004872 0,06232198 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02004872 0,06224157 ! axonal fasciculation GO:0007413 18 7 0,000 0,02004872 0,06216136 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02004872 0,06208136 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02004872 0,06200156 ! diuresis GO:0030146 12 7 0,000 0,02004872 0,06192197 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02004872 0,06184258 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02004872 0,0617634 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02004872 0,06168442 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02004872 0,06160564 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02004872 0,06152706 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02004872 0,06144868 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02004872 0,0613705 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02004872 0,06129252 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02004872 0,06121474 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02004872 0,06113716 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02004872 0,06105977 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02004872 0,06098257 ! lymph node development GO:0048535 10 7 0,000 0,02004872 0,06090558 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02004872 0,06082877 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02004872 0,06075216 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02004872 0,06067574 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02004872 0,06059952 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02004872 0,06052348 ! adult feeding behavior GO:0008343 9 7 0,000 0,02004872 0,06044764 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02004872 0,06037199 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02004872 0,06029652 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02004872 0,06022124 ! muscle adaptation GO:0043500 14 7 0,000 0,02004872 0,06014615 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02004872 0,06007125 ! retina homeostasis GO:0001895 12 7 0,000 0,02004872 0,05999654 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02004872 0,05992201 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02004872 0,05984766 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02004872 0,0597735 ! protein prenylation GO:0018342 18 7 0,000 0,02004872 0,05969952 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02004872 0,05962573 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02004872 0,05955212 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02004872 0,05947869 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,02047368 0,06066462 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02098072 0,06209054 ! protein oligomerization GO:0051259 139 78 1,000 0,02149298 0,06352839 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02288019 0,0675457 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02288019 0,06746293 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02288019 0,06738035 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02288019 0,06729798 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02288019 0,06721581 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02288019 0,06713384 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02288019 0,06705207 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02288019 0,0669705 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02288019 0,06688912 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02288019 0,06680795 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02288019 0,06672697 ! meiotic prophase I GO:0007128 13 8 0,000 0,02288019 0,06664619 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02288019 0,0665656 ! oligopeptide transport GO:0006857 15 8 0,000 0,02288019 0,0664852 ! UTP metabolic process GO:0046051 8 8 0,000 0,02288019 0,066405 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02288019 0,066325 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02288019 0,06624519 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02288019 0,06616556 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02288019 0,06608613 ! succinate metabolic process GO:0006105 14 8 0,000 0,02288019 0,06600689 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02288019 0,06592784 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02288019 0,06584898 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02288019 0,06577031 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02288019 0,06569182 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02288019 0,06561353 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02288019 0,06553542 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02288019 0,06545749 ! reflex GO:0060004 16 8 0,000 0,02288019 0,06537975 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02288019 0,06530219 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02288019 0,06522482 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02288019 0,06514763 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02288019 0,06507063 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02288019 0,0649938 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02288019 0,06491716 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02288019 0,06484069 ! pigment granule organization GO:0048753 16 8 0,000 0,02288019 0,06476441 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02288019 0,06468831 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02288019 0,06461238 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02288019 0,06453663 ! histidine metabolic process GO:0006547 16 8 0,000 0,02288019 0,06446106 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02288019 0,06438567 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02288019 0,06431045 ! glycine catabolic process GO:0006546 13 8 0,000 0,02288019 0,06423541 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02288019 0,06416055 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02288019 0,06408585 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02288019 0,06401134 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02288019 0,06393699 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02288019 0,06386282 ! melanin metabolic process GO:0006582 15 8 0,000 0,02288019 0,06378882 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02288019 0,06371499 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02288019 0,06364133 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02288019 0,06356784 ! macrophage activation GO:0042116 12 8 0,000 0,02288019 0,06349452 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02288019 0,06342137 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02288019 0,06334839 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02288019 0,06327557 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02288019 0,06320293 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02288019 0,06313045 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02288019 0,06305813 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02288019 0,06298598 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02288019 0,062914 ! osteoblast development GO:0002076 16 8 0,000 0,02288019 0,06284218 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02288019 0,06277052 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02288019 0,06269903 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02288019 0,0626277 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02288019 0,06255653 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02288019 0,06248553 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02288019 0,06241468 ! response to UV-B GO:0010224 16 8 0,000 0,02288019 0,062344 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02288019 0,06227347 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02288019 0,06220311 ! intermediate filament organization GO:0045109 12 8 0,000 0,02288019 0,0621329 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02288019 0,06206285 ! cellular extravasation GO:0045123 12 8 0,000 0,02288019 0,06199296 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02288019 0,06192323 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02288019 0,06185365 ! response to antibiotic GO:0046677 11 8 0,000 0,02288019 0,06178423 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02288019 0,06171497 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02288019 0,06164586 ! DNA topological change GO:0006265 12 8 0,000 0,02288019 0,0615769 ! response to tropane GO:0014073 15 8 0,000 0,02288019 0,0615081 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02288019 0,06143945 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02288019 0,06137096 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02288019 0,06130262 ! mast cell activation GO:0045576 14 8 0,000 0,02288019 0,06123443 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02288019 0,06116639 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02288019 0,0610985 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02288019 0,06103076 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02288019 0,06096318 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02288019 0,06089574 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02288019 0,06082845 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02288019 0,06076131 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02288019 0,06069432 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02288019 0,06062748 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02288019 0,06056078 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02288019 0,06049423 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02288019 0,06042783 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02288019 0,06036157 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02288019 0,06029545 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02288019 0,06022948 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02288019 0,06016366 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02288019 0,06009798 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02288019 0,06003244 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02288019 0,05996705 ! hormone catabolic process GO:0042447 17 8 0,000 0,02288019 0,05990179 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02288019 0,05983668 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02288019 0,05977171 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02288019 0,05970689 ! ATP catabolic process GO:0006200 11 8 0,000 0,02288019 0,0596422 ! blastocyst growth GO:0001832 19 8 0,000 0,02288019 0,05957765 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02288019 0,05951324 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02288019 0,05944897 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02288019 0,05938484 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02288019 0,05932085 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02288019 0,059257 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02288019 0,05919328 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02288019 0,0591297 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02288019 0,05906625 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02288019 0,05900295 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02288019 0,05893977 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02288019 0,05887674 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02288019 0,05881383 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02288019 0,05875107 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02288019 0,05868843 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02288019 0,05862593 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02288019 0,05856356 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02306073 0,05896293 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,02306073 0,05890034 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,02359353 0,06019727 ! negative regulation of growth GO:0045926 155 84 1,000 0,02467424 0,06288795 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0252221 0,06421626 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0252221 0,06414837 GO:0002696|positive regulation of leukocyte activation, ! regulation of developmental growth GO:0048638 15 9 0,000 0,02570358 0,06530393 ! axon extension GO:0048675 15 9 0,000 0,02570358 0,06523505 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02570358 0,0651663 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02570358 0,06509771 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02570358 0,06502926 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02570358 0,06496095 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02570358 0,06489278 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02570358 0,06482476 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02570358 0,06475688 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02570358 0,06468915 ! phosphate transport GO:0006817 19 9 0,000 0,02570358 0,06462155 ! reproductive behavior GO:0019098 19 9 0,000 0,02570358 0,0645541 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02570358 0,06448678 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02570358 0,06441961 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02570358 0,06435257 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02570358 0,06428568 ! GTP metabolic process GO:0046039 9 9 0,000 0,02570358 0,06421892 ! RNA methylation GO:0001510 15 9 0,000 0,02570358 0,06415231 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02570358 0,06408583 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02570358 0,06401949 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02570358 0,06395328 ! artery development GO:0060840 24 9 0,000 0,02570358 0,06388721 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02570358 0,06382128 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02570358 0,06375549 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02570358 0,06368983 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02570358 0,0636243 ! chemosensory behavior GO:0007635 20 9 0,000 0,02570358 0,06355891 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02570358 0,06349366 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02570358 0,06342854 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02570358 0,06336355 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02570358 0,06329869 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02570358 0,06323397 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02570358 0,06316938 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02570358 0,06310492 ! protein targeting to ER GO:0045047 22 9 0,000 0,02570358 0,06304059 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02570358 0,0629764 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02570358 0,06291233 ! T cell selection GO:0045058 23 9 0,000 0,02570358 0,0628484 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02570358 0,06278459 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02570358 0,06272092 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02570358 0,06265737 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02570358 0,06259395 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02570358 0,06253066 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02570358 0,0624675 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02570358 0,06240446 ! mannose metabolic process GO:0006013 13 9 0,000 0,02570358 0,06234156 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02570358 0,06227877 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02570358 0,06221612 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02570358 0,06215359 ! receptor clustering GO:0043113 18 9 0,000 0,02570358 0,06209119 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02570358 0,06202891 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02570358 0,06196676 ! ruffle organization GO:0031529 15 9 0,000 0,02570358 0,06190473 ! retinol metabolic process GO:0042572 18 9 0,000 0,02570358 0,06184282 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02570358 0,06178104 ! behavioral fear response GO:0001662 22 9 0,000 0,02570358 0,06171938 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02570358 0,06165785 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02570358 0,06159644 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02570358 0,06153515 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,02570358 0,06147398 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02570358 0,06141293 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02570358 0,06135201 ! segment specification GO:0007379 13 9 0,000 0,02570358 0,0612912 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02570358 0,06123052 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02570358 0,06116995 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02570358 0,06110951 ! response to amine stimulus GO:0014075 13 9 0,000 0,02570358 0,06104918 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02570358 0,06098898 ! erythrocyte development GO:0048821 15 9 0,000 0,02570358 0,06092889 ! gas homeostasis GO:0033483 16 9 0,000 0,02570358 0,06086892 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02570358 0,06080907 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02570358 0,06074934 ! renal water homeostasis GO:0003091 14 9 0,000 0,02570358 0,06068972 ! postreplication repair GO:0006301 22 9 0,000 0,02570358 0,06063022 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02570358 0,06057084 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02570358 0,06051157 ! icosanoid secretion GO:0032309 15 9 0,000 0,02570358 0,06045242 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02570358 0,06039338 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02570358 0,06033446 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02570358 0,06027566 ! regulation of cell division GO:0051302 15 9 0,000 0,02570358 0,06021697 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02570358 0,06015839 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02570358 0,06009993 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02570358 0,06004158 ! sterol catabolic process GO:0016127 11 9 0,000 0,02570358 0,05998334 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02570358 0,05992522 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02570358 0,05986721 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02570358 0,05980931 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02570358 0,05975152 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02570358 0,05969384 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02570358 0,05963628 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02570358 0,05957883 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02570358 0,05952149 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02570358 0,05946425 ! purine base metabolic process GO:0006144 21 9 0,000 0,02570358 0,05940713 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02570358 0,05935012 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02570358 0,05929321 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02570358 0,05923642 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02570358 0,05917974 ! mitochondrion localization GO:0051646 15 9 0,000 0,02570358 0,05912316 ! chromatin assembly GO:0031497 124 86 1,000 0,0257749 0,05923057 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,02633263 0,06045448 ! gland development GO:0048732 206 88 1,000 0,02689524 0,06168727 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02746271 0,06292884 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02746271 0,06286896 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,028035 0,06411808 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,028035 0,06405719 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02851891 0,06510104 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02851891 0,06503933 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02851891 0,06497774 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02851891 0,06491627 ! synapsis GO:0007129 13 10 0,000 0,02851891 0,06485491 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02851891 0,06479367 ! N-glycan processing GO:0006491 20 10 0,000 0,02851891 0,06473254 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02851891 0,06467153 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02851891 0,06461063 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02851891 0,06454985 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02851891 0,06448919 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02851891 0,06442863 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02851891 0,06436819 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02851891 0,06430787 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02851891 0,06424765 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02851891 0,06418755 ! androgen metabolic process GO:0008209 17 10 0,000 0,02851891 0,06412756 ! phospholipid efflux GO:0033700 16 10 0,000 0,02851891 0,06406769 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02851891 0,06400792 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02851891 0,06394827 ! lung alveolus development GO:0048286 26 10 0,000 0,02851891 0,06388873 ! pathogenesis GO:0009405 13 10 0,000 0,02851891 0,0638293 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02851891 0,06376998 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02851891 0,06371076 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02851891 0,06365166 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02851891 0,06359267 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02851891 0,06353379 ! endoderm development GO:0007492 16 10 0,000 0,02851891 0,06347502 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02851891 0,06341635 ! arginine catabolic process GO:0006527 13 10 0,000 0,02851891 0,0633578 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02851891 0,06329935 ! proline metabolic process GO:0006560 13 10 0,000 0,02851891 0,06324101 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02851891 0,06318278 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 28 10 0,000 0,02851891 0,06312465 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02851891 0,06306663 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02851891 0,06300872 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02851891 0,06295091 ! B cell proliferation GO:0042100 18 10 0,000 0,02851891 0,06289321 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02851891 0,06283562 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02851891 0,06277813 ! multicellular organism growth GO:0035264 18 10 0,000 0,02851891 0,06272074 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02851891 0,06266346 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02851891 0,06260629 ! epithelial cell development GO:0002064 20 10 0,000 0,02851891 0,06254922 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02851891 0,06249225 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02851891 0,06243539 ! macroautophagy GO:0016236 17 10 0,000 0,02851891 0,06237863 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02851891 0,06232197 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02851891 0,06226542 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02851891 0,06220897 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02851891 0,06215262 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02851891 0,06209637 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02851891 0,06204023 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02851891 0,06198419 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02851891 0,06192824 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02851891 0,0618724 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02851891 0,06181666 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02851891 0,06176102 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02851891 0,06170548 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02851891 0,06165004 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02851891 0,0615947 ! DNA ligation GO:0006266 19 10 0,000 0,02851891 0,06153946 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02851891 0,06148431 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02851891 0,06142927 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02851891 0,06137432 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02851891 0,06131948 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02851891 0,06126473 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02851891 0,06121007 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02851891 0,06115552 ! mRNA cleavage GO:0006379 17 10 0,000 0,02851891 0,06110106 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02851891 0,0610467 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02851891 0,06099244 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02851891 0,06093827 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02851891 0,0608842 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02851891 0,06083022 ! salivary gland development GO:0007431 27 10 0,000 0,02851891 0,06077635 ! prophase GO:0051324 15 10 0,000 0,02851891 0,06072256 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02851891 0,06066887 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02851891 0,06061528 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02851891 0,06056178 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02851891 0,06050837 ! midbrain development GO:0030901 13 10 0,000 0,02851891 0,06045506 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02851891 0,06040184 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02851891 0,06034872 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02851891 0,06029569 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02851891 0,06024275 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02851891 0,06018991 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02851891 0,06013715 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02851891 0,0600845 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02851891 0,06003193 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02851891 0,05997945 ! oocyte development GO:0048599 17 10 0,000 0,02851891 0,05992707 ! blastocyst formation GO:0001825 17 10 0,000 0,02851891 0,05987478 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02851891 0,05982258 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02851891 0,05977046 ! activation of innate immune response GO:0002218 12 10 0,000 0,02851891 0,05971845 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02851891 0,05966652 ! response to nicotine GO:0035094 20 10 0,000 0,02851891 0,05961468 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02851891 0,05956293 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02851891 0,05951127 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02851891 0,0594597 ! localization within membrane GO:0051668 20 10 0,000 0,02851891 0,05940822 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02978051 0,06198262 ! transcription initiation GO:0006352 153 94 1,000 0,03037178 0,06315861 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03037178 0,06310407 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,03096772 0,06428674 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03132619 0,06497484 ! respiratory burst GO:0045730 17 11 0,000 0,03132619 0,06491888 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03132619 0,06486301 ! neuron fate specification GO:0048665 17 11 0,000 0,03132619 0,06480724 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03132619 0,06475156 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03132619 0,06469598 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03132619 0,06464049 ! thyroid gland development GO:0030878 26 11 0,000 0,03132619 0,0645851 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,03132619 0,06452981 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03132619 0,06447461 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03132619 0,0644195 ! response to pain GO:0048265 24 11 0,000 0,03132619 0,06436449 ! T cell proliferation GO:0042098 26 11 0,000 0,03132619 0,06430957 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03132619 0,06425474 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03132619 0,06420001 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03132619 0,06414537 ! bone resorption GO:0045453 16 11 0,000 0,03132619 0,06409083 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03132619 0,06403638 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03132619 0,06398202 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03132619 0,06392775 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03132619 0,06387357 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03132619 0,06381949 ! syncytium formation GO:0006949 18 11 0,000 0,03132619 0,0637655 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03132619 0,06371159 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03132619 0,06365778 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03132619 0,06360406 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03132619 0,06355043 ! lipid digestion GO:0044241 18 11 0,000 0,03132619 0,0634969 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03132619 0,06344345 ! UV protection GO:0009650 19 11 0,000 0,03132619 0,06339009 ! adult heart development GO:0007512 14 11 0,000 0,03132619 0,06333682 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03132619 0,06328364 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03132619 0,06323055 ! temperature homeostasis GO:0001659 17 11 0,000 0,03132619 0,06317755 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03132619 0,06312464 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03132619 0,06307181 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03132619 0,06301908 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03132619 0,06296643 ! regulation of organ growth GO:0046620 13 11 0,000 0,03132619 0,06291387 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03132619 0,0628614 ! vasoconstriction GO:0042310 18 11 0,000 0,03132619 0,06280901 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03132619 0,06275672 ! embryonic axis specification GO:0000578 18 11 0,000 0,03132619 0,06270451 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03132619 0,06265238 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03132619 0,06260035 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03132619 0,06254839 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03132619 0,06249653 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03132619 0,06244475 ! zymogen activation GO:0031638 15 11 0,000 0,03132619 0,06239306 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03132619 0,06234145 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03132619 0,06228993 ! nucleosome positioning GO:0016584 15 11 0,000 0,03132619 0,06223849 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03132619 0,06218714 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03132619 0,06213587 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03132619 0,06208469 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03132619 0,06203359 ! acid secretion GO:0046717 18 11 0,000 0,03132619 0,06198258 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03132619 0,06193165 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03132619 0,0618808 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03132619 0,06183004 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03132619 0,06177936 ! oocyte differentiation GO:0009994 18 11 0,000 0,03132619 0,06172876 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03132619 0,06167825 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03132619 0,06162781 ! cholesterol efflux GO:0033344 19 11 0,000 0,03132619 0,06157746 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03132619 0,0615272 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03132619 0,06147701 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03132619 0,06142691 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03132619 0,06137689 ! embryonic gut development GO:0048566 15 11 0,000 0,03132619 0,06132695 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03132619 0,06127709 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03132619 0,06122731 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03132619 0,06117761 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03132619 0,06112799 ! defense response to fungus GO:0050832 13 11 0,000 0,03132619 0,06107846 ! developmental induction GO:0031128 19 11 0,000 0,03132619 0,061029 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03132619 0,06097962 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03132619 0,06093033 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03132619 0,06088111 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03132619 0,06083197 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03132619 0,06078292 ! nucleus localization GO:0051647 19 11 0,000 0,03132619 0,06073394 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03132619 0,06068504 ! mRNA transport GO:0051028 169 96 1,000 0,03156829 0,06110484 ! positive regulation of immune response GO:0050778 156 96 1,000 0,03156829 0,06105572 ! detection of stimulus GO:0051606 151 96 1,000 0,03156829 0,06100668 ! interphase GO:0051325 213 98 1,000 0,03278322 0,06330371 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,03278322 0,06325294 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 1,000 0,03339751 0,06438654 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03339751 0,06433499 GO:0060538|skeletal muscle organ development, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03412545 0,06568467 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03412545 0,06563217 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03412545 0,06557975 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03412545 0,06552741 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03412545 0,06547515 ! virus-host interaction GO:0019048 29 12 0,000 0,03412545 0,06542298 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03412545 0,06537089 ! cartilage condensation GO:0001502 20 12 0,000 0,03412545 0,06531889 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03412545 0,06526697 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03412545 0,06521513 ! protein complex disassembly GO:0043241 27 12 0,000 0,03412545 0,06516337 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03412545 0,06511169 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03412545 0,0650601 ! hippocampus development GO:0021766 26 12 0,000 0,03412545 0,06500859 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03412545 0,06495715 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03412545 0,0649058 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03412545 0,06485454 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03412545 0,06480335 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03412545 0,06475224 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03412545 0,06470122 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03412545 0,06465027 ! drug transport GO:0015893 16 12 0,000 0,03412545 0,0645994 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03412545 0,06454862 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03412545 0,06449791 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03412545 0,06444729 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03412545 0,06439674 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03412545 0,06434627 ! forebrain cell migration GO:0021885 21 12 0,000 0,03412545 0,06429588 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03412545 0,06424557 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03412545 0,06419534 ! entry into host cell GO:0030260 32 12 0,000 0,03412545 0,06414519 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03412545 0,06409512 ! monoamine transport GO:0015844 18 12 0,000 0,03412545 0,06404512 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03412545 0,0639952 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03412545 0,06394536 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03412545 0,0638956 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03412545 0,06384591 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03412545 0,0637963 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03412545 0,06374677 ! protein homotetramerization GO:0051289 21 12 0,000 0,03412545 0,06369732 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03412545 0,06364794 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03412545 0,06359864 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03412545 0,06354941 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03412545 0,06350027 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03412545 0,06345119 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03412545 0,0634022 ! cranial nerve development GO:0021545 20 12 0,000 0,03412545 0,06335327 ! fucose catabolic process GO:0019317 22 12 0,000 0,03412545 0,06330443 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03412545 0,06325566 ! histone acetylation GO:0016573 26 12 0,000 0,03412545 0,06320696 ! histone methylation GO:0016571 26 12 0,000 0,03412545 0,06315834 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03412545 0,06310979 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03412545 0,06306132 ! gland morphogenesis GO:0022612 29 12 0,000 0,03412545 0,06301293 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03412545 0,0629646 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03412545 0,06291635 ! T cell homeostasis GO:0043029 25 12 0,000 0,03412545 0,06286818 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03412545 0,06282008 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03412545 0,06277205 ! spleen development GO:0048536 22 12 0,000 0,03412545 0,0627241 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03412545 0,06267622 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03412545 0,06262841 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03412545 0,06258067 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03412545 0,06253301 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03412545 0,06248542 ! response to cold GO:0009409 17 12 0,000 0,03412545 0,0624379 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03412545 0,06239046 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03412545 0,06234309 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03691672 0,06739122 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03691672 0,06734013 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03691672 0,06728911 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03691672 0,06723818 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03691672 0,06718732 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03691672 0,06713653 ! lipid localization GO:0010876 28 13 0,000 0,03691672 0,06708582 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03691672 0,06703519 ! organelle fusion GO:0048284 32 13 0,000 0,03691672 0,06698464 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03691672 0,06693416 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03691672 0,06688376 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03691672 0,06683343 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03691672 0,06678318 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03691672 0,06673301 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03691672 0,06668291 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03691672 0,06663288 ! methionine metabolic process GO:0006555 27 13 0,000 0,03691672 0,06658293 ! plasma membrane organization GO:0007009 24 13 0,000 0,03691672 0,06653306 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03691672 0,06648326 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03691672 0,06643353 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03691672 0,06638388 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03691672 0,0663343 ! response to X-ray GO:0010165 25 13 0,000 0,03691672 0,0662848 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03691672 0,06623537 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03691672 0,06618601 ! exocrine system development GO:0035272 32 13 0,000 0,03691672 0,06613673 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,03691672 0,06608752 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03691672 0,06603839 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03691672 0,06598932 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03691672 0,06594033 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03691672 0,06589142 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03691672 0,06584257 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03691672 0,0657938 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03691672 0,0657451 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03691672 0,06569647 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03691672 0,06564792 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03691672 0,06559943 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03691672 0,06555102 ! ribosome assembly GO:0042255 17 13 0,000 0,03691672 0,06550268 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,03691672 0,06545441 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03691672 0,06540621 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03691672 0,06535808 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03691672 0,06531002 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03691672 0,06526204 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03691672 0,06521412 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03691672 0,06516627 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03691672 0,0651185 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03691672 0,06507079 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03691672 0,06502316 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03691672 0,06497559 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03691672 0,06492809 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03691672 0,06488067 ! embryonic placenta development GO:0001892 23 13 0,000 0,03691672 0,06483331 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03691672 0,06478602 ! insulin secretion GO:0030073 23 13 0,000 0,03691672 0,0647388 ! actin filament polymerization GO:0030041 24 13 0,000 0,03691672 0,06469165 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03691672 0,06464456 ! acrosome reaction GO:0007340 18 13 0,000 0,03691672 0,06459755 ! rRNA transcription GO:0009303 25 14 0,000 0,03970001 0,06941732 ! lactation GO:0007595 26 14 0,000 0,03970001 0,06936691 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03970001 0,06931657 ! reproductive cellular process GO:0048610 20 14 0,000 0,03970001 0,0692663 ! tRNA modification GO:0006400 20 14 0,000 0,03970001 0,06921611 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03970001 0,06916599 ! regulation of S phase GO:0033261 23 14 0,000 0,03970001 0,06911594 ! water transport GO:0006833 21 14 0,000 0,03970001 0,06906597 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03970001 0,06901606 ! non-recombinational repair GO:0000726 25 14 0,000 0,03970001 0,06896623 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03970001 0,06891647 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03970001 0,06886679 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03970001 0,06881717 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03970001 0,06876763 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03970001 0,06871815 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03970001 0,06866875 ! palate development GO:0060021 31 14 0,000 0,03970001 0,06861942 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03970001 0,06857016 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03970001 0,06852097 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03970001 0,06847185 ! arginine metabolic process GO:0006525 17 14 0,000 0,03970001 0,0684228 ! regulation of heart rate GO:0002027 24 14 0,000 0,03970001 0,06837382 ! organic alcohol transport GO:0015850 29 14 0,000 0,03970001 0,06832492 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03970001 0,06827608 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03970001 0,06822731 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03970001 0,06817861 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03970001 0,06812998 ! L-amino acid transport GO:0015807 30 14 0,000 0,03970001 0,06808142 ! bone mineralization GO:0030282 17 14 0,000 0,03970001 0,06803293 ! stem cell development GO:0048864 43 14 0,000 0,03970001 0,06798451 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03970001 0,06793615 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03970001 0,06788787 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03970001 0,06783965 ! cerebellum development GO:0021549 21 14 0,000 0,03970001 0,06779151 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03970001 0,06774343 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03970001 0,06769542 ! response to gamma radiation GO:0010332 28 14 0,000 0,03970001 0,06764747 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03970001 0,0675996 ! cofactor transport GO:0051181 26 14 0,000 0,03970001 0,06755179 ! NADP metabolic process GO:0006739 24 14 0,000 0,03970001 0,06750405 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03970001 0,06745638 ! intestinal absorption GO:0050892 25 14 0,000 0,03970001 0,06740877 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03970001 0,06736124 ! oxygen transport GO:0015671 21 14 0,000 0,03970001 0,06731377 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03970001 0,06726636 ! male genitalia development GO:0030539 24 14 0,000 0,03970001 0,06721902 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03970001 0,06717175 ! regulation of axon extension GO:0030516 37 14 0,000 0,03970001 0,06712455 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03970001 0,06707741 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04247536 0,07171628 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04247536 0,07166599 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,04247536 0,07161577 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04247536 0,07156562 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04247536 0,07151554 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04247536 0,07146553 ! copper ion transport GO:0006825 20 15 0,000 0,04247536 0,07141559 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04247536 0,07136572 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04247536 0,07131591 ! sulfate transport GO:0008272 23 15 0,000 0,04247536 0,07126618 ! response to cAMP GO:0051591 22 15 0,000 0,04247536 0,07121652 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04247536 0,07116693 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04247536 0,0711174 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04247536 0,07106794 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04247536 0,07101856 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04247536 0,07096924 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04247536 0,07091999 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04247536 0,07087081 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04247536 0,07082169 ! pituitary gland development GO:0021983 29 15 0,000 0,04247536 0,07077265 ! vesicle coating GO:0006901 33 15 0,000 0,04247536 0,07072367 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04247536 0,07067476 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04247536 0,07062592 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04247536 0,07057714 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04247536 0,07052844 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04247536 0,0704798 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04247536 0,07043122 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04247536 0,07038272 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04247536 0,07033428 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04247536 0,0702859 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04247536 0,0702376 ! histone deacetylation GO:0016575 20 15 0,000 0,04247536 0,07018936 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04247536 0,07014118 ! tissue regeneration GO:0042246 26 15 0,000 0,04247536 0,07009308 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04247536 0,07004503 ! water homeostasis GO:0030104 27 15 0,000 0,04247536 0,06999706 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04247536 0,06994915 ! muscle maintenance GO:0046716 26 15 0,000 0,04247536 0,0699013 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04247536 0,06985352 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04247536 0,06980581 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04247536 0,06975816 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04247536 0,06971058 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04247536 0,06966306 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04247536 0,0696156 ! detection of bacterium GO:0016045 18 15 0,000 0,04247536 0,06956821 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04247536 0,06952089 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04247536 0,06947363 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04247536 0,06942643 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04247536 0,0693793 ! peptide hormone processing GO:0016486 23 15 0,000 0,04247536 0,06933223 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04524277 0,07379939 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04524277 0,07374939 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04524277 0,07369946 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04524277 0,07364959 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04524277 0,0735998 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04524277 0,07355007 ! bone remodeling GO:0046849 27 16 0,000 0,04524277 0,0735004 ! filopodium assembly GO:0046847 32 16 0,000 0,04524277 0,07345081 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04524277 0,07340128 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04524277 0,07335182 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04524277 0,07330242 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04524277 0,07325309 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04524277 0,07320383 ! startle response GO:0001964 28 16 0,000 0,04524277 0,07315464 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04524277 0,07310551 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04524277 0,07305644 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04524277 0,07300744 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04524277 0,07295851 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04524277 0,07290964 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04524277 0,07286084 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04524277 0,07281211 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04524277 0,07276343 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04524277 0,07271483 ! response to osmotic stress GO:0006970 25 16 0,000 0,04524277 0,07266629 ! lysosomal transport GO:0007041 26 16 0,000 0,04524277 0,07261781 ! fructose metabolic process GO:0006000 25 16 0,000 0,04524277 0,0725694 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04524277 0,07252105 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04524277 0,07247277 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04524277 0,07242455 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04524277 0,0723764 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04524277 0,0723283 ! axon cargo transport GO:0008088 43 16 0,000 0,04524277 0,07228028 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04524277 0,07223231 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04524277 0,07218442 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04524277 0,07213658 ! DNA replication initiation GO:0006270 27 16 0,000 0,04524277 0,07208881 ! neuron recognition GO:0008038 35 16 0,000 0,04524277 0,0720411 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04524277 0,07199345 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04524277 0,07194587 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04524277 0,07189835 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04524277 0,07185089 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04524277 0,07180349 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04524277 0,07175616 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04524277 0,07170889 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04524277 0,07166168 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04524277 0,07161454 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04524277 0,07156745 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04524277 0,07152043 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04524277 0,07147347 ! defense response to virus GO:0051607 37 16 0,000 0,04524277 0,07142657 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04800227 0,07573342 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04800227 0,07568379 ! metencephalon development GO:0022037 30 17 0,000 0,04800227 0,07563423 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04800227 0,07558473 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04800227 0,0755353 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04800227 0,07548593 ! signal complex assembly GO:0007172 41 17 0,000 0,04800227 0,07543662 ! endothelial cell migration GO:0043542 28 17 0,000 0,04800227 0,07538738 ! inositol metabolic process GO:0006020 28 17 0,000 0,04800227 0,07533821 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04800227 0,07528909 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04800227 0,07524004 ! glial cell development GO:0021782 27 17 0,000 0,04800227 0,07519106 ! limbic system development GO:0021761 36 17 0,000 0,04800227 0,07514214 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04800227 0,07509328 ! adult walking behavior GO:0007628 33 17 0,000 0,04800227 0,07504449 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04800227 0,07499576 ! myoblast differentiation GO:0045445 45 17 0,000 0,04800227 0,07494709 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04800227 0,07489849 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04800227 0,07484995 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04800227 0,07480147 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04800227 0,07475305 ! glycine metabolic process GO:0006544 28 17 0,000 0,04800227 0,0747047 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,04800227 0,07465641 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04800227 0,07460818 ! NAD metabolic process GO:0019674 29 17 0,000 0,04800227 0,07456002 ! membrane budding GO:0006900 37 17 0,000 0,04800227 0,07451192 ! DNA integration GO:0015074 29 17 0,000 0,04800227 0,07446387 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04800227 0,07441589 ! regulation of protein binding GO:0043393 33 17 0,000 0,04800227 0,07436798 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04800227 0,07432012 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04800227 0,07427233 ! genitalia development GO:0048806 30 17 0,000 0,04800227 0,07422459 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04800227 0,07417692 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04800227 0,07412931 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04800227 0,07408176 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04800227 0,07403427 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04800227 0,07398685 ! steroid catabolic process GO:0006706 31 17 0,000 0,04800227 0,07393948 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04800227 0,07389217 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04800227 0,07384493 ! gas transport GO:0015669 25 17 0,000 0,04800227 0,07379774 ! organic cation transport GO:0015695 31 17 0,000 0,04800227 0,07375062 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04800227 0,07370355 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04800227 0,07365655 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04800227 0,0736096 ! microspike assembly GO:0030035 36 17 0,000 0,04800227 0,07356272 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05075389 0,07773003 ! neuron maturation GO:0042551 42 18 0,000 0,05075389 0,07768058 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05075389 0,0776312 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05075389 0,07758187 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,05075389 0,07753262 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05075389 0,07748342 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05075389 0,07743429 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05075389 0,07738522 ! memory GO:0007613 31 18 0,000 0,05075389 0,07733621 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05075389 0,07728726 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05075389 0,07723837 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05075389 0,07718955 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05075389 0,07714079 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05075389 0,07709209 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05075389 0,07704345 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05075389 0,07699487 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05075389 0,07694636 ! response to retinoic acid GO:0032526 26 18 0,000 0,05075389 0,0768979 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05075389 0,07684951 ! response to fungus GO:0009620 21 18 0,000 0,05075389 0,07680118 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05075389 0,0767529 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05075389 0,07670469 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05075389 0,07665654 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05075389 0,07660845 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05075389 0,07656042 ! vitamin transport GO:0051180 27 18 0,000 0,05075389 0,07651245 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05075389 0,07646454 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05075389 0,07641669 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05075389 0,0763689 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05075389 0,07632117 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,05075389 0,0762735 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05075389 0,07622589 ! nerve development GO:0021675 28 18 0,000 0,05075389 0,07617833 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05075389 0,07613084 ! protein secretion GO:0009306 39 19 0,000 0,05349765 0,08019648 ! positive regulation of translation GO:0045727 30 19 0,000 0,05349765 0,08014655 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05349765 0,08009667 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05349765 0,08004686 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05349765 0,07999711 ! lipid phosphorylation GO:0046834 35 19 0,000 0,05349765 0,07994743 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05349765 0,0798978 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05349765 0,07984823 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05349765 0,07979873 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05349765 0,07974929 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05349765 0,07969991 ! cerebral cortex development GO:0021987 36 19 0,000 0,05349765 0,07965059 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05349765 0,07960133 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05349765 0,07955214 ! heme metabolic process GO:0042168 36 19 0,000 0,05349765 0,079503 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05349765 0,07945392 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05349765 0,07940491 ! peptide cross-linking GO:0018149 37 19 0,000 0,05349765 0,07935595 ! protein export from nucleus GO:0006611 36 19 0,000 0,05349765 0,07930706 ! heart process GO:0003015 30 19 0,000 0,05349765 0,07925822 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05349765 0,07920945 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05349765 0,07916073 ! visual learning GO:0008542 36 19 0,000 0,05349765 0,07911208 ! G1 phase GO:0051318 40 19 0,000 0,05349765 0,07906349 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05349765 0,07901495 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05349765 0,07896648 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05349765 0,07891806 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05349765 0,0788697 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05349765 0,07882141 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05349765 0,07877317 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05349765 0,07872499 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05349765 0,07867687 ! cilium assembly GO:0042384 37 19 0,000 0,05349765 0,07862881 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05349765 0,0785808 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05623357 0,0825491 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05623357 0,08249877 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05623357 0,08244849 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05623357 0,08239828 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05623357 0,08234813 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,05623357 0,08229804 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,05623357 0,08224801 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05623357 0,08219804 ! response to vitamin GO:0033273 31 20 0,000 0,05623357 0,08214813 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05623357 0,08209829 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,05623357 0,0820485 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05623357 0,08199877 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05623357 0,08194911 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05623357 0,0818995 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05623357 0,08184996 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05623357 0,08180047 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05623357 0,08175104 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05623357 0,08170168 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,05623357 0,08165237 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05623357 0,08160312 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05623357 0,08155393 ! body fluid secretion GO:0007589 31 20 0,000 0,05623357 0,08150481 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05623357 0,08145574 ! peptide secretion GO:0002790 35 20 0,000 0,05623357 0,08140672 ! stem cell differentiation GO:0048863 53 20 0,000 0,05623357 0,08135777 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05623357 0,08130888 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05623357 0,08126005 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05623357 0,08121127 ! sensory perception of pain GO:0019233 30 20 0,000 0,05623357 0,08116255 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05623357 0,0811139 ! diencephalon development GO:0021536 34 20 0,000 0,05623357 0,08106529 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05623357 0,08101675 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05623357 0,08096827 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05623357 0,08091984 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05623357 0,08087147 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05623357 0,08082316 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05623357 0,08077491 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05623357 0,08072672 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05623357 0,08067858 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05623357 0,0806305 ! regulation of glucose import GO:0046324 29 20 0,000 0,05623357 0,08058248 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05623357 0,08053451 ! actin filament-based movement GO:0030048 43 20 0,000 0,05623357 0,0804866 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05623357 0,08043875 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05623357 0,08039095 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05623357 0,08034322 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05623357 0,08029554 ! regulation of cell killing GO:0031341 42 21 0,000 0,05896167 0,08414104 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05896167 0,08409116 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05896167 0,08404134 ! hormone secretion GO:0046879 38 21 0,000 0,05896167 0,08399159 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05896167 0,08394189 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05896167 0,08389225 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05896167 0,08384267 ! axis specification GO:0009798 38 21 0,000 0,05896167 0,08379314 ! ovarian follicle development GO:0001541 35 21 0,000 0,05896167 0,08374368 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05896167 0,08369427 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05896167 0,08364492 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05896167 0,08359563 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05896167 0,0835464 ! cell aging GO:0007569 44 21 0,000 0,05896167 0,08349723 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05896167 0,08344811 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05896167 0,08339905 ! cytolysis GO:0019835 24 21 0,000 0,05896167 0,08335005 ! vasodilation GO:0042311 39 21 0,000 0,05896167 0,08330111 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05896167 0,08325222 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05896167 0,0832034 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05896167 0,08315462 ! oogenesis GO:0048477 36 21 0,000 0,05896167 0,08310591 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05896167 0,08305725 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05896167 0,08300865 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05896167 0,08296011 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05896167 0,08291162 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05896167 0,08286319 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05896167 0,08281482 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05896167 0,08276651 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05896167 0,08271824 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05896167 0,08267004 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05896167 0,08262189 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05896167 0,0825738 ! collagen catabolic process GO:0030574 28 21 0,000 0,05896167 0,08252576 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05896167 0,08247778 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06168198 0,08623291 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06168198 0,08618284 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06168198 0,08613282 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06168198 0,08608286 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06168198 0,08603295 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06168198 0,08598311 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06168198 0,08593332 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06168198 0,08588359 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06168198 0,08583392 ! regeneration GO:0031099 41 22 0,000 0,06168198 0,0857843 ! keratinization GO:0031424 28 22 0,000 0,06168198 0,08573475 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06168198 0,08568525 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06168198 0,0856358 ! sensory perception of taste GO:0050909 28 22 0,000 0,06168198 0,08558642 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06168198 0,08553709 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06168198 0,08548781 ! vacuolar transport GO:0007034 36 22 0,000 0,06168198 0,0854386 ! lysosome organization GO:0007040 41 22 0,000 0,06168198 0,08538944 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06168198 0,08534034 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06168198 0,08529129 ! fucose metabolic process GO:0006004 39 22 0,000 0,06168198 0,0852423 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06168198 0,08519337 ! ureteric bud development GO:0001657 43 22 0,000 0,06168198 0,08514449 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06168198 0,08509567 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06168198 0,0850469 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06168198 0,08499819 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,06168198 0,08494954 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06168198 0,08490094 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06168198 0,0848524 ! sarcomere organization GO:0045214 30 22 0,000 0,06168198 0,08480391 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06168198 0,08475548 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06168198 0,0847071 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06168198 0,08465878 ! protein stabilization GO:0050821 39 22 0,000 0,06168198 0,08461052 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,06439451 0,08828103 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06439451 0,08823075 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06439451 0,08818053 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06439451 0,08813038 ! gluconeogenesis GO:0006094 33 23 0,000 0,06439451 0,08808027 ! viral genome replication GO:0019079 41 23 0,000 0,06439451 0,08803023 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06439451 0,08798024 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06439451 0,08793031 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06439451 0,08788043 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06439451 0,08783061 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06439451 0,08778085 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06439451 0,08773114 ! visual behavior GO:0007632 42 23 0,000 0,06439451 0,08768149 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06439451 0,0876319 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06439451 0,08758236 ! response to ethanol GO:0045471 46 23 0,000 0,06439451 0,08753288 ! peroxisome organization GO:0007031 37 23 0,000 0,06439451 0,08748346 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06439451 0,08743409 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06439451 0,08738477 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06439451 0,08733551 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06439451 0,08728631 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,06439451 0,08723716 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06439451 0,08718807 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06439451 0,08713903 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06439451 0,08709005 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06439451 0,08704112 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06439451 0,08699225 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06439451 0,08694343 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06439451 0,08689467 ! fatty acid transport GO:0015908 44 23 0,000 0,06439451 0,08684596 ! platelet activation GO:0030168 37 23 0,000 0,06439451 0,08679731 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06439451 0,08674871 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06439451 0,08670017 ! hormone transport GO:0009914 40 23 0,000 0,06439451 0,08665168 ! cell-cell recognition GO:0009988 25 23 0,000 0,06439451 0,08660324 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06439451 0,08655486 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06439451 0,08650653 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06439451 0,08645826 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06439451 0,08641004 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06709929 0,08998935 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06709929 0,08993922 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,06709929 0,08988914 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06709929 0,08983912 ! vesicle docking GO:0048278 47 24 0,000 0,06709929 0,08978916 ! spinal cord development GO:0021510 47 24 0,000 0,06709929 0,08973925 ! vacuole organization GO:0007033 43 24 0,000 0,06709929 0,08968939 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06709929 0,08963959 ! digestive system process GO:0022600 39 24 0,000 0,06709929 0,08958985 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06709929 0,08954016 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06709929 0,08949052 ! regulation of behavior GO:0050795 43 24 0,000 0,06709929 0,08944094 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06709929 0,08939142 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06709929 0,08934195 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06709929 0,08929253 ! membrane depolarization GO:0051899 39 24 0,000 0,06709929 0,08924317 ! pallium development GO:0021543 49 24 0,000 0,06709929 0,08919387 ! pentose metabolic process GO:0019321 35 24 0,000 0,06709929 0,08914462 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,06709929 0,08909542 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06709929 0,08904628 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06709929 0,08899719 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06709929 0,08894816 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06709929 0,08889918 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06709929 0,08885025 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06709929 0,08880138 ! regulation of amine transport GO:0051952 40 24 0,000 0,06709929 0,08875256 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06979635 0,09226924 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06979635 0,09221857 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06979635 0,09216795 ! phototransduction GO:0007602 33 25 0,000 0,06979635 0,09211739 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06979635 0,09206689 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06979635 0,09201644 ! sperm motility GO:0030317 31 25 0,000 0,06979635 0,09196605 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06979635 0,09191571 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06979635 0,09186543 ! receptor metabolic process GO:0043112 46 25 0,000 0,06979635 0,0918152 ! response to starvation GO:0042594 42 25 0,000 0,06979635 0,09176503 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06979635 0,09171491 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,06979635 0,09166485 ! neural crest cell development GO:0014032 54 25 0,000 0,06979635 0,09161484 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06979635 0,09156489 ! negative regulation of cell development GO:0010721 73 25 0,000 0,06979635 0,09151499 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06979635 0,09146515 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06979635 0,09141536 ! interaction with host GO:0051701 62 25 0,000 0,06979635 0,09136562 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06979635 0,09131594 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06979635 0,09126631 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06979635 0,09121673 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,06979635 0,09116721 ! immunoglobulin production GO:0002377 55 25 0,000 0,06979635 0,09111775 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06979635 0,09106833 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06979635 0,09101897 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06979635 0,09096967 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,06979635 0,09092042 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06979635 0,09087122 ! telomere organization GO:0032200 43 25 0,000 0,06979635 0,09082207 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06979635 0,09077298 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06979635 0,09072394 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07248569 0,09416877 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07248569 0,09411795 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07248569 0,09406719 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07248569 0,09401648 ! initiation of viral infection GO:0019059 57 26 0,000 0,07248569 0,09396582 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07248569 0,09391522 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07248569 0,09386468 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07248569 0,09381418 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07248569 0,09376375 ! molting cycle process GO:0022404 50 26 0,000 0,07248569 0,09371336 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07248569 0,09366303 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07248569 0,09361276 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07248569 0,09356254 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07248569 0,09351237 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07248569 0,09346225 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07248569 0,09341219 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07248569 0,09336219 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07248569 0,09331224 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07248569 0,09326234 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07248569 0,09321249 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07248569 0,0931627 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07248569 0,09311296 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07248569 0,09306327 ! blastocyst development GO:0001824 49 26 0,000 0,07248569 0,09301364 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07248569 0,09296406 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07248569 0,09291453 ! neuron fate commitment GO:0048663 48 27 0,000 0,07516735 0,09630066 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,07516735 0,09624941 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07516735 0,09619821 ! iron ion transport GO:0006826 59 27 0,000 0,07516735 0,09614707 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07516735 0,09609598 ! protein amino acid acylation GO:0043543 55 27 0,000 0,07516735 0,09604495 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07516735 0,09599397 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07516735 0,09594304 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07516735 0,09589217 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07516735 0,09584135 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07516735 0,09579059 ! autophagy GO:0006914 41 27 0,000 0,07516735 0,09573988 ! male gonad development GO:0008584 44 27 0,000 0,07516735 0,09568922 ! response to toxin GO:0009636 47 27 0,000 0,07516735 0,09563862 ! primary neural tube formation GO:0014020 51 27 0,000 0,07516735 0,09558807 ! base-excision repair GO:0006284 41 27 0,000 0,07516735 0,09553758 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07516735 0,09548714 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07516735 0,09543675 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07516735 0,09538641 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07516735 0,09533613 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07516735 0,0952859 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07516735 0,09523572 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07784134 0,09857172 ! circadian rhythm GO:0007623 50 28 0,000 0,07784134 0,09851986 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07784134 0,09846807 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07784134 0,09841632 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,07784134 0,09836463 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07784134 0,098313 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07784134 0,09826142 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07784134 0,09820989 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07784134 0,09815842 ! synaptogenesis GO:0007416 42 28 0,000 0,07784134 0,098107 ! lipid oxidation GO:0034440 43 28 0,000 0,07784134 0,09805563 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07784134 0,09800432 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07784134 0,09795307 ! translational initiation GO:0006413 65 29 0,000 0,08050769 0,10125536 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08050769 0,10120246 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08050769 0,10114961 ! regulation of pH GO:0006885 43 29 0,000 0,08050769 0,10109682 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08050769 0,10104408 ! catechol metabolic process GO:0009712 54 29 0,000 0,08050769 0,1009914 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08050769 0,10093877 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08050769 0,1008862 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08050769 0,10083368 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08050769 0,10078122 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08050769 0,10072881 ! cell fate determination GO:0001709 60 29 0,000 0,08050769 0,10067645 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08050769 0,10062416 ! detection of light stimulus GO:0009583 38 29 0,000 0,08050769 0,10057191 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08050769 0,10051972 ! tissue homeostasis GO:0001894 48 29 0,000 0,08050769 0,10046758 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08050769 0,1004155 ! phenol metabolic process GO:0018958 55 30 0,000 0,08316642 0,10367793 ! zinc ion transport GO:0006829 45 30 0,000 0,08316642 0,10362424 ! membrane docking GO:0022406 61 30 0,000 0,08316642 0,1035706 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08316642 0,10351702 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08316642 0,1034635 ! acute-phase response GO:0006953 49 30 0,000 0,08316642 0,10341003 ! myofibril assembly GO:0030239 47 30 0,000 0,08316642 0,10335661 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08316642 0,10330325 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08316642 0,10324995 ! phospholipid transport GO:0015914 51 30 0,000 0,08316642 0,1031967 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08316642 0,10314351 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08316642 0,10309037 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08316642 0,10303728 ! eye morphogenesis GO:0048592 60 30 0,000 0,08316642 0,10298425 ! response to heat GO:0009408 50 30 0,000 0,08316642 0,10293128 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08581755 0,10615785 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08581755 0,1061033 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08581755 0,1060488 ! collagen metabolic process GO:0032963 45 31 0,000 0,08581755 0,10599436 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08581755 0,10593998 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08581755 0,10588565 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08581755 0,10583138 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08581755 0,10577716 ! ovulation cycle process GO:0022602 49 31 0,000 0,08581755 0,105723 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08581755 0,10566889 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08581755 0,10561484 ! peptide transport GO:0015833 55 31 0,000 0,08581755 0,10556085 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08581755 0,10550691 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08581755 0,10545302 ! mesoderm formation GO:0001707 69 31 0,000 0,08581755 0,10539919 ! natural killer cell activation GO:0030101 45 31 0,000 0,08581755 0,10534542 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08581755 0,1052917 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08581755 0,10523803 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,08581755 0,10518442 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08581755 0,10513086 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0884611 0,1083142 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0884611 0,10825911 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0884611 0,10820407 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0884611 0,10814909 ! cholesterol transport GO:0030301 56 32 0,000 0,0884611 0,10809416 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0884611 0,10803929 ! spliceosome assembly GO:0000245 67 32 0,000 0,0884611 0,10798448 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0884611 0,10792972 ! metanephros development GO:0001656 74 32 0,000 0,0884611 0,10787501 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0884611 0,10782037 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0884611 0,10776577 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0884611 0,10771124 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0884611 0,10765675 ! muscle cell development GO:0055001 49 32 0,000 0,0884611 0,10760233 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0884611 0,10754795 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0884611 0,10749364 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0884611 0,10743937 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0884611 0,10738517 ! ovulation cycle GO:0042698 51 32 0,000 0,0884611 0,10733101 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0884611 0,10727692 ! hindbrain development GO:0030902 61 32 0,000 0,0884611 0,10722287 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0884611 0,10716888 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0884611 0,10711495 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0884611 0,10706107 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,09109709 0,11019588 ! post-embryonic development GO:0009791 69 33 0,000 0,09109709 0,1101405 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,09109709 0,11008518 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09109709 0,11002992 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09109709 0,10997471 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09109709 0,10991956 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09109709 0,10986446 ! cell fate specification GO:0001708 52 33 0,000 0,09109709 0,10980942 ! sterol transport GO:0015918 57 33 0,000 0,09109709 0,10975443 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09109709 0,1096995 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09109709 0,10964462 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09109709 0,1095898 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09109709 0,10953503 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09372555 0,1126392 ! glial cell differentiation GO:0010001 63 34 0,000 0,09372555 0,11258296 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09372555 0,11252678 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09372555 0,11247066 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09372555 0,11241459 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09372555 0,11235858 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09372555 0,11230263 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09372555 0,11224673 ! mismatch repair GO:0006298 46 34 0,000 0,09372555 0,11219088 ! spermatid development GO:0007286 63 34 0,000 0,09372555 0,11213509 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09372555 0,11207936 ! placenta development GO:0001890 53 34 0,000 0,09372555 0,11202368 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,09372555 0,11196806 ! regulation of muscle development GO:0048634 70 35 0,000 0,0963465 0,11504202 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0963465 0,11498495 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0963465 0,11492795 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0963465 0,11487099 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0963465 0,1148141 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0963465 0,11475726 ! odontogenesis GO:0042476 66 35 0,000 0,0963465 0,11470048 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0963465 0,11464375 ! female gonad development GO:0008585 58 35 0,000 0,0963465 0,11458708 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0963465 0,11453047 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0963465 0,11447391 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0963465 0,11441741 ! cytokine production GO:0001816 59 35 0,000 0,0963465 0,11436096 ! neural tube formation GO:0001841 67 35 0,000 0,0963465 0,11430457 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,09895995 0,11734728 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09895995 0,11728947 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09895995 0,11723172 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09895995 0,11717403 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,09895995 0,1171164 ! positive regulation of cell development GO:0010720 80 36 0,000 0,09895995 0,11705882 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,09895995 0,11700129 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09895995 0,11694383 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09895995 0,11688642 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09895995 0,11682906 ! aerobic respiration GO:0009060 55 36 0,000 0,09895995 0,11677177 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,09895995 0,11671453 ! embryonic organ development GO:0048568 57 36 0,000 0,09895995 0,11665734 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,09895995 0,11660021 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10156593 0,11961215 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10156593 0,11955363 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10156593 0,11949517 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10156593 0,11943676 ! organic anion transport GO:0015711 68 37 0,000 0,10156593 0,11937842 ! tissue remodeling GO:0048771 76 37 0,000 0,10156593 0,11932013 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,10156593 0,11926189 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,10156593 0,11920372 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10156593 0,1191456 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10156593 0,11908753 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10156593 0,11902953 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,10156593 0,11897158 ! glycogen metabolic process GO:0005977 61 37 0,000 0,10156593 0,11891368 ! pigment metabolic process GO:0042440 80 37 0,000 0,10156593 0,11885585 ! spermatid differentiation GO:0048515 66 37 0,000 0,10156593 0,11879807 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10416446 0,12177827 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,10416446 0,12171913 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10416446 0,12166004 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10416446 0,12160101 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10416446 0,12154204 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,10416446 0,12148312 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,10416446 0,12142426 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10416446 0,12136546 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,10416446 0,12130672 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10416446 0,12124803 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10416446 0,1211894 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10416446 0,12113083 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10416446 0,12107231 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10416446 0,12101385 ! glucan metabolic process GO:0044042 62 38 0,000 0,10416446 0,12095544 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,10675556 0,12390442 ! learning GO:0007612 77 39 0,000 0,10675556 0,12384468 ! organic ether metabolic process GO:0018904 55 39 0,000 0,10675556 0,123785 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,10675556 0,12372537 ! segmentation GO:0035282 67 39 0,000 0,10675556 0,1236658 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10675556 0,12360629 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10675556 0,12354683 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,10675556 0,12348744 ! RNA modification GO:0009451 57 39 0,000 0,10675556 0,1234281 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,10675556 0,12336881 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,10933925 0,12629392 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,10933925 0,12623332 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,10933925 0,12617277 ! feeding behavior GO:0007631 59 40 0,000 0,10933925 0,12611229 ! negative regulation of binding GO:0051100 72 40 0,000 0,10933925 0,12605186 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,10933925 0,12599149 ! mesenchymal cell development GO:0014031 87 40 0,000 0,10933925 0,12593118 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,10933925 0,12587092 ! maintenance of protein location GO:0045185 91 40 0,000 0,10933925 0,12581073 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11191555 0,12871358 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11191555 0,12865209 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11191555 0,12859065 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11191555 0,12852927 ! gliogenesis GO:0042063 88 41 0,000 0,11191555 0,12846795 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11191555 0,12840668 ! T cell differentiation GO:0030217 81 41 0,000 0,11191555 0,12834548 ! female gamete generation GO:0007292 61 41 0,000 0,11191555 0,12828433 ! polyol metabolic process GO:0019751 66 41 0,000 0,11191555 0,12822325 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11191555 0,12816222 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,11448449 0,13104171 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 0,000 0,11448449 0,1309794 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11448449 0,13091715 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11448449 0,13085495 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11448449 0,13079282 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,11448449 0,13073074 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11448449 0,13066873 ! neuron migration GO:0001764 79 42 0,000 0,11448449 0,13060677 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11448449 0,13054487 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,11704608 0,13340259 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11704608 0,13333943 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11704608 0,13327632 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,11704608 0,13321328 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11704608 0,13315029 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,11704608 0,13308737 ! neural tube development GO:0021915 77 43 0,000 0,11704608 0,1330245 ! striated muscle contraction GO:0006941 77 43 0,000 0,11704608 0,13296169 ! phagocytosis GO:0006909 90 43 0,000 0,11704608 0,13289895 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11704608 0,13283626 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,11960034 0,13567111 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,11960034 0,13560718 ! male sex differentiation GO:0046661 76 44 0,000 0,11960034 0,1355433 ! double-strand break repair GO:0006302 81 44 0,000 0,11960034 0,13547949 ! B cell differentiation GO:0030183 107 44 0,000 0,11960034 0,13541573 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,11960034 0,13535204 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,11960034 0,1352884 ! developmental growth GO:0048589 82 44 0,000 0,11960034 0,13522483 ! maintenance of location in cell GO:0051651 97 44 0,000 0,11960034 0,13516131 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12214731 0,13797484 ! glycolysis GO:0006096 65 45 0,000 0,12214731 0,1379101 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,12214731 0,13784541 ! leukocyte migration GO:0050900 68 45 0,000 0,12214731 0,13778079 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12214731 0,13771622 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12214731 0,13765172 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12214731 0,13758727 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12214731 0,13752289 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12214731 0,13745857 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12214731 0,13739431 ! cell growth GO:0016049 84 45 0,000 0,12214731 0,1373301 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12468698 0,14011998 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,12468698 0,14005457 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,12468698 0,13998921 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,12468698 0,13992392 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,12468698 0,13985869 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1272194 0,14263275 ! response to calcium ion GO:0051592 81 47 0,000 0,1272194 0,14256631 ! endosome transport GO:0016197 108 47 0,000 0,1272194 0,14249994 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,1272194 0,14243363 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,1272194 0,14236738 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1272194 0,1423012 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1272194 0,14223507 ! JNK cascade GO:0007254 91 47 0,000 0,1272194 0,14216901 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1272194 0,142103 ! protein homooligomerization GO:0051260 76 47 0,000 0,1272194 0,14203706 ! mitochondrial transport GO:0006839 82 48 0,000 0,12974457 0,14478916 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12974457 0,14472204 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,12974457 0,14465497 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,12974457 0,14458797 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12974457 0,14452103 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,12974457 0,14445416 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,12974457 0,14438734 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13226252 0,14712142 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,13226252 0,14705343 ! regulation of ion transport GO:0043269 77 49 0,000 0,13226252 0,14698551 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13226252 0,14691765 ! peptide metabolic process GO:0006518 76 49 0,000 0,13226252 0,14684985 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13226252 0,14678211 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,13226252 0,14671444 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,13226252 0,14664683 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,13226252 0,14657928 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13226252 0,1465118 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13477327 0,14922434 ! neuromuscular process GO:0050905 99 50 0,000 0,13477327 0,14915569 ! regulation of ossification GO:0030278 117 50 0,000 0,13477327 0,14908712 ! inner ear development GO:0048839 79 50 0,000 0,13477327 0,1490186 ! histone modification GO:0016570 91 50 0,000 0,13477327 0,14895015 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,13477327 0,14888176 ! positive regulation of binding GO:0051099 78 51 0,000 0,13727683 0,15157782 ! viral infectious cycle GO:0019058 99 51 0,000 0,13727683 0,15150828 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,13727683 0,15143882 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,13727683 0,15136941 ! excretion GO:0007588 83 51 0,000 0,13727683 0,15130007 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,13727683 0,1512308 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,13727683 0,15116158 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,13727683 0,15109243 ! vesicle organization GO:0016050 107 51 0,000 0,13727683 0,15102335 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,13727683 0,15095432 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,13977324 0,15362924 ! membrane fusion GO:0006944 110 52 0,000 0,13977324 0,15355909 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,13977324 0,15348901 ! amino acid activation GO:0043038 92 52 0,000 0,13977324 0,15341898 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,13977324 0,15334902 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1422625 0,15600892 ! RNA catabolic process GO:0006401 93 53 0,000 0,1422625 0,15593785 ! regulation of translational initiation GO:0006446 82 53 0,000 0,1422625 0,15586684 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1422625 0,15579589 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1422625 0,15572501 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,1422625 0,1556542 ! cell maturation GO:0048469 100 53 0,000 0,1422625 0,15558345 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,1422625 0,15551276 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,1422625 0,15544213 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,14474465 0,15808244 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14474465 0,15801072 ! cell recognition GO:0008037 85 54 0,000 0,14474465 0,15793906 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,14474465 0,15786746 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14474465 0,15779593 ! chloride transport GO:0006821 90 55 0,000 0,14721969 0,16042145 ! glucose catabolic process GO:0006007 82 55 0,000 0,14721969 0,16034883 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,14721969 0,16027628 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,14721969 0,16020379 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,14721969 0,16013136 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,14721969 0,160059 ! aging GO:0007568 103 55 0,000 0,14721969 0,15998671 ! gastrulation GO:0007369 112 55 0,000 0,14721969 0,15991448 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,14721969 0,15984232 ! RNA elongation GO:0006354 79 55 0,000 0,14721969 0,15977022 ! nuclear export GO:0051168 97 55 0,000 0,14721969 0,15969818 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,14721969 0,15962622 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14968765 0,16222905 ! sensory perception of smell GO:0007608 80 56 0,000 0,14968765 0,16215601 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14968765 0,16208303 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,14968765 0,16201012 ! regulation of DNA replication GO:0006275 101 56 0,000 0,14968765 0,16193727 ! proton transport GO:0015992 94 56 0,000 0,14968765 0,16186449 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,15214855 0,16445167 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,15214855 0,16437783 ! lipid modification GO:0030258 97 57 0,000 0,15214855 0,16430405 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,15214855 0,16423034 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,15214855 0,16415669 ! maintenance of location GO:0051235 118 57 0,000 0,15214855 0,16408311 ! hydrogen transport GO:0006818 97 58 0,000 0,15460241 0,16665475 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,15460241 0,16658012 ! regulation of endocytosis GO:0030100 91 58 0,000 0,15460241 0,16650556 ! adult behavior GO:0030534 99 58 0,000 0,15460241 0,16643106 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,15460241 0,16635662 ! positive regulation of secretion GO:0051047 95 59 0,000 0,15704926 0,16891395 ! regulation of cellular component size GO:0032535 109 59 0,000 0,15704926 0,16883848 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,15704926 0,16876307 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,15704926 0,16868773 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1594891 0,17123193 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1594891 0,17115556 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1594891 0,17107925 ! camera-type eye development GO:0043010 116 60 0,000 0,1594891 0,17100301 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1594891 0,17092684 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16192196 0,17345691 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,16192196 0,17337972 ! mesoderm development GO:0007498 119 61 0,000 0,16192196 0,17330259 ! tRNA processing GO:0008033 89 61 0,000 0,16192196 0,17322553 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16192196 0,17314854 ! viral reproductive process GO:0022415 126 62 0,000 0,16434785 0,17566456 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,16434785 0,17558656 ! gonad development GO:0008406 98 62 0,000 0,16434785 0,17550863 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,16676681 0,17801284 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,16676681 0,1779339 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,16676681 0,17785503 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,16917884 0,1803475 ! cell redox homeostasis GO:0045454 102 64 0,000 0,16917884 0,18026763 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,16917884 0,18018783 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,16917884 0,1801081 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,16917884 0,18002844 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,17158398 0,18250709 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,17158398 0,18242645 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,17158398 0,18234587 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,17158398 0,18226536 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,17398223 0,18473135 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,17398223 0,18464986 ! extracellular matrix organization GO:0030198 133 66 0,000 0,17398223 0,18456845 ! secondary metabolic process GO:0019748 116 66 0,000 0,17398223 0,1844871 ! developmental maturation GO:0021700 116 66 0,000 0,17398223 0,18440583 ! cell projection assembly GO:0030031 120 66 0,000 0,17398223 0,18432463 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,17637361 0,18677593 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,17637361 0,18669376 ! activation of MAPK activity GO:0000187 115 67 0,000 0,17637361 0,18661166 ! lung development GO:0030324 144 67 0,000 0,17637361 0,18652963 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,17637361 0,18644768 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,17637361 0,18636579 ! hexose catabolic process GO:0019320 104 67 0,000 0,17637361 0,18628398 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,17637361 0,18620224 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,17637361 0,18612057 ! adaptive immune response GO:0002250 119 67 0,000 0,17637361 0,18603898 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 0,000 0,17875815 0,18847157 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,17875815 0,18838901 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,17875815 0,18830653 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,17875815 0,18822412 ! viral reproduction GO:0016032 134 68 0,000 0,17875815 0,18814178 ! regulation of lipase activity GO:0060191 130 68 0,000 0,17875815 0,18805952 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,17875815 0,18797732 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,17875815 0,1878952 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,18113587 0,19031131 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,18113587 0,19022824 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,18113587 0,19014525 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,18113587 0,19006232 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,18113587 0,18997947 ! antigen processing and presentation GO:0019882 104 69 0,000 0,18113587 0,18989669 ! appendage morphogenesis GO:0035107 135 70 0,000 0,18350678 0,19229849 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,18350678 0,19221477 ! reproductive structure development GO:0048608 113 71 0,000 0,18587091 0,19460636 ! appendage development GO:0048736 136 71 0,000 0,18587091 0,19452171 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,18587091 0,19443714 ! B cell activation GO:0042113 160 71 0,000 0,18587091 0,19435263 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,18587091 0,19426821 ! regulation of immune effector process GO:0002697 137 71 0,000 0,18587091 0,19418385 ! acute inflammatory response GO:0002526 113 72 0,000 0,18822827 0,19656129 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,18822827 0,19647602 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,18822827 0,19639082 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,18822827 0,19630569 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,18822827 0,19622063 ! respiratory system development GO:0060541 153 72 0,000 0,18822827 0,19613565 ! learning or memory GO:0007611 147 73 0,000 0,19057888 0,19849904 ! regulation of blood pressure GO:0008217 125 73 0,000 0,19057888 0,19841315 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,19057888 0,19832733 ! fertilization GO:0009566 90 73 0,000 0,19057888 0,19824159 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,19292277 0,20059299 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,19292277 0,20050634 ! neurotransmitter transport GO:0006836 123 74 0,000 0,19292277 0,20041977 ! exocytosis GO:0006887 133 74 0,000 0,19292277 0,20033327 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,19292277 0,20024684 ! eye development GO:0001654 143 74 0,000 0,19292277 0,20016049 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,19525994 0,20249802 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,19525994 0,20241078 ! rhythmic process GO:0048511 128 75 0,000 0,19525994 0,20232361 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,19525994 0,20223651 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,19759042 0,2045622 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,19759042 0,20447422 ! defense response to bacterium GO:0042742 89 76 0,000 0,19759042 0,20438631 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,19759042 0,20429848 ! regulation of catabolic process GO:0009894 161 76 0,000 0,19759042 0,20421072 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,19991424 0,20652368 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,19991424 0,20643504 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,19991424 0,20634648 ! blood coagulation GO:0007596 146 78 0,000 0,2022314 0,20864869 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,2022314 0,20855925 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,2022314 0,2084699 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,20454192 0,2107614 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,20454192 0,21067117 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,20454192 0,21058103 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,20454192 0,21049096 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,20454192 0,21040097 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,20454192 0,21031105 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,20684583 0,21258909 ! response to metal ion GO:0010038 140 80 0,000 0,20684583 0,21249832 ! muscle cell differentiation GO:0042692 159 80 0,000 0,20684583 0,21240763 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,20684583 0,21231701 ! protein import into nucleus GO:0006606 158 80 0,000 0,20684583 0,21222647 ! inorganic anion transport GO:0015698 138 80 0,000 0,20684583 0,21213601 ! T cell activation GO:0042110 168 81 0,000 0,20914314 0,21440068 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,20914314 0,21430937 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,20914314 0,21421814 ! digestion GO:0007586 112 81 0,000 0,20914314 0,21412698 ! nuclear import GO:0051170 161 81 0,000 0,20914314 0,2140359 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,20914314 0,2139449 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,21143388 0,21619631 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,21143388 0,21610447 ! response to nutrient GO:0007584 125 82 0,000 0,21143388 0,2160127 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,21143388 0,21592102 ! response to oxygen levels GO:0070482 176 83 0,000 0,21371806 0,21816107 ! regulation of lyase activity GO:0051339 160 83 0,000 0,21371806 0,21806855 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,21599569 0,22029913 ! hemostasis GO:0007599 158 84 0,000 0,21599569 0,22020578 ! negative regulation of transport GO:0051051 153 84 0,000 0,21599569 0,22011251 ! regulation of ligase activity GO:0051340 142 84 0,000 0,21599569 0,22001932 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,21599569 0,21992621 ! response to unfolded protein GO:0006986 131 85 0,000 0,21826681 0,22214464 ! nucleosome assembly GO:0006334 122 85 0,000 0,21826681 0,22205071 ! response to inorganic substance GO:0010035 153 86 0,000 0,22053142 0,22425976 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,22053142 0,22416502 ! tube morphogenesis GO:0035239 176 86 0,000 0,22053142 0,22407035 ! alcohol catabolic process GO:0046164 130 86 0,000 0,22053142 0,22397577 ! amine transport GO:0015837 155 86 0,000 0,22053142 0,22388126 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,22278954 0,2260783 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 0,000 0,22278954 0,22598299 ! regulation of protein transport GO:0051223 154 87 0,000 0,22278954 0,22588776 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,2250412 0,22807461 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,2250412 0,22797858 ! regulation of DNA binding GO:0051101 155 88 0,000 0,2250412 0,22788263 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2250412 0,22778676 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2250412 0,22769097 ! cellular defense response GO:0006968 114 89 0,000 0,22728641 0,22986596 ! ossification GO:0001503 188 90 0,000 0,22952519 0,23203261 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,22952519 0,23193516 ! sex differentiation GO:0007548 145 90 0,000 0,22952519 0,23183779 ! bone development GO:0060348 189 91 0,000 0,23175756 0,23399441 ! sterol metabolic process GO:0016125 152 91 0,000 0,23175756 0,23389626 ! response to protein stimulus GO:0051789 149 91 0,000 0,23175756 0,23379819 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,23175756 0,23370021 ! regulation of defense response GO:0031347 149 92 0,000 0,23398353 0,23584599 ! nucleosome organization GO:0034728 138 92 0,000 0,23398353 0,23574723 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,23398353 0,23564855 ! vitamin metabolic process GO:0006766 139 92 0,000 0,23398353 0,23554995 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,23620313 0,23768496 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,23620313 0,23758559 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,23620313 0,23748631 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,23620313 0,23738711 ! female pregnancy GO:0007565 164 94 0,000 0,23841637 0,2395114 ! forebrain development GO:0030900 188 95 0,000 0,24062327 0,24162754 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,24062327 0,24152674 ! leukocyte differentiation GO:0002521 202 96 0,000 0,24282385 0,24363394 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,24282385 0,24353238 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,24501813 0,24563067 ! protein ubiquitination GO:0016567 217 97 0,000 0,24501813 0,24552837 ! hormone metabolic process GO:0042445 157 97 0,000 0,24501813 0,24542615 ! regulation of protein localization GO:0032880 176 97 0,000 0,24501813 0,24532402 ! response to virus GO:0009615 160 98 0,000 0,24720612 0,24741178 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,24720612 0,2473089 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,24938784 0,24938784