pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6121-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of embryonic development GO:0045995 27 11 3,000 2,765E-08 6,653E-05 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 3,000 1,507E-07 1,813E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,791E-07 2,238E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 3,123E-07 1,879E-04 ! activation of caspase activity GO:0006919 84 48 4,000 3,883E-07 1,868E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,974E-07 1,594E-04 ! nuclear migration GO:0007097 12 6 2,000 5,663E-07 1,946E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 5,663E-07 1,703E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of caspase activity GO:0043280 95 55 4,000 7,755E-07 2,073E-04 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 83 56 4,000 8,494E-07 2,044E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 8,634E-07 1,889E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 9,888E-07 1,982E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 9,888E-07 1,83E-04 ! macrophage differentiation GO:0030225 11 7 2,000 9,888E-07 1,699E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 9,888E-07 1,586E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,025E-06 1,542E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,209E-06 1,711E-04 GO:0045936|negative regulation of phosphate metabolic process, ! ER overload response GO:0006983 12 8 2,000 1,578E-06 2,11E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,578E-06 1,999E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,578E-06 1,899E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,578E-06 1,808E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 1,648E-06 1,802E-04 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 1,907E-06 1,995E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 2,091E-06 2,096E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 2,251E-06 2,167E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 2,362E-06 2,186E-04 ! regulation of caspase activity GO:0043281 122 72 4,000 2,993E-06 2,667E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 2,993E-06 2,571E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 3,367E-06 2,794E-04 ! protein sumoylation GO:0016925 15 10 2,000 3,367E-06 2,701E-04 ! regulation of endopeptidase activity GO:0052548 125 74 4,000 3,429E-06 2,661E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 4,62E-06 3,473E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 4,62E-06 3,368E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 4,62E-06 3,269E-04 ! regulation of peptidase activity GO:0052547 134 79 4,000 4,739E-06 3,258E-04 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 6,146E-06 4,107E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,146E-06 3,996E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 6,146E-06 3,891E-04 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of transport GO:0051051 153 84 4,000 6,413E-06 3,956E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 8,519E-06 5,124E-04 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 8,716E-06 5,115E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 1,012E-05 5,799E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,012E-05 5,664E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,172E-05 6,408E-04 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,259E-05 6,73E-04 ! pigmentation GO:0043473 100 46 3,000 1,259E-05 6,584E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,263E-05 6,463E-04 ! detection of bacterium GO:0016045 18 15 2,000 1,263E-05 6,328E-04 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,297E-05 6,369E-04 ! interphase GO:0051325 213 98 4,000 1,364E-05 6,562E-04 ! cell cycle arrest GO:0007050 213 100 4,000 1,504E-05 7,097E-04 ! filopodium assembly GO:0046847 32 16 2,000 1,55E-05 7,174E-04 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 1,55E-05 7,038E-04 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,55E-05 6,908E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 1,623E-05 7,099E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,878E-05 8,071E-04 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,878E-05 7,929E-04 ! microspike assembly GO:0030035 36 17 2,000 1,878E-05 7,792E-04 ! regulation of DNA replication GO:0006275 101 56 3,000 2,767E-05 1,128E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,969E-05 1,191E-03 ! regulation of glucose import GO:0046324 29 20 2,000 3,128E-05 1,234E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 3,128E-05 1,214E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 3,641E-05 1,391E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 3,641E-05 1,369E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 3,641E-05 1,348E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 2,000 3,641E-05 1,327E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 3,641E-05 1,308E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 3,641E-05 1,288E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 3,886E-05 1,355E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 4,207E-05 1,446E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 4,207E-05 1,426E-03 ! detection of external stimulus GO:0009581 91 63 3,000 4,414E-05 1,475E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 4,827E-05 1,591E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 5,504E-05 1,79E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 5,504E-05 1,766E-03 ! regulation of behavior GO:0050795 43 24 2,000 5,504E-05 1,742E-03 ! protein tetramerization GO:0051262 52 24 2,000 5,504E-05 1,72E-03 ! negative regulation of cell development GO:0010721 73 25 2,000 6,241E-05 1,925E-03 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 2,000 6,241E-05 1,901E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,039E-05 2,117E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 7,039E-05 2,091E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 7,464E-05 2,19E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 7,901E-05 2,29E-03 ! base-excision repair GO:0006284 41 27 2,000 7,901E-05 2,263E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 7,901E-05 2,236E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 8,83E-05 2,47E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 8,83E-05 2,442E-03 ! steroid biosynthetic process GO:0006694 131 76 3,000 9,221E-05 2,521E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,376E-05 2,535E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,376E-05 2,507E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 9,376E-05 2,479E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 9,376E-05 2,452E-03 ! decidualization GO:0046697 11 5 1,000 9,376E-05 2,426E-03 ! mitotic recombination GO:0006312 9 5 1,000 9,376E-05 2,4E-03 ! stem cell division GO:0017145 11 5 1,000 9,376E-05 2,375E-03 GO:0048103|somatic stem cell division, ! positive regulation of phosphorylation GO:0042327 129 79 3,000 1,072E-04 2,687E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,089E-04 2,702E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 1,182E-04 2,901E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 1,325E-04 3,22E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,325E-04 3,188E-03 ! protein lipoylation GO:0009249 10 6 1,000 1,404E-04 3,344E-03 ! male sex determination GO:0030238 15 6 1,000 1,404E-04 3,311E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,404E-04 3,279E-03 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,404E-04 3,247E-03 ! maternal placenta development GO:0001893 12 6 1,000 1,404E-04 3,216E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 1,404E-04 3,186E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,454E-04 3,27E-03 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 2,000 1,454E-04 3,24E-03 ! mitochondrion organization GO:0007005 148 86 3,000 1,491E-04 3,291E-03 ! regulation of protein transport GO:0051223 154 87 3,000 1,559E-04 3,41E-03 GO:0070201|regulation of establishment of protein localization, ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,591E-04 3,449E-03 ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,629E-04 3,5E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,89E-04 4,025E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,961E-04 4,139E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,961E-04 4,103E-03 ! protein-cofactor linkage GO:0018065 13 7 1,000 1,961E-04 4,068E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,961E-04 4,033E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,961E-04 3,999E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,961E-04 3,965E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,961E-04 3,932E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,961E-04 3,9E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,016E-04 3,976E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,052E-04 4,015E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,052E-04 3,982E-03 ! nucleus organization GO:0006997 67 38 2,000 2,223E-04 4,28E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 2,278E-04 4,35E-03 ! detection of stimulus GO:0051606 151 96 3,000 2,278E-04 4,315E-03 ! regulation of protein localization GO:0032880 176 97 3,000 2,37E-04 4,455E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,61E-04 4,867E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 2,61E-04 4,83E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2,61E-04 4,793E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,61E-04 4,757E-03 ! glycine catabolic process GO:0006546 13 8 1,000 2,61E-04 4,721E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 2,61E-04 4,686E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 2,61E-04 4,651E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 2,61E-04 4,617E-03 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,791E-04 4,901E-03 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,791E-04 4,866E-03 ! negative regulation of protein complex disassembly GO:0043242 101 42 2,000 2,999E-04 5,191E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 3,216E-04 5,528E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,348E-04 5,714E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,348E-04 5,673E-03 ! DNA synthesis during DNA repair GO:0000731 14 9 1,000 3,348E-04 5,634E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,348E-04 5,595E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 3,348E-04 5,556E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 3,348E-04 5,518E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,348E-04 5,48E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,348E-04 5,443E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,348E-04 5,407E-03 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 3,348E-04 5,371E-03 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 3,348E-04 5,335E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 3,348E-04 5,3E-03 ! leukocyte migration GO:0050900 68 45 2,000 3,682E-04 5,79E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,93E-04 6,14E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 3,93E-04 6,1E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,177E-04 6,442E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 4,177E-04 6,401E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 4,177E-04 6,361E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 4,177E-04 6,321E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,177E-04 6,281E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 4,177E-04 6,242E-03 GO:0045685|regulation of glial cell differentiation, ! apical protein localization GO:0045176 15 10 1,000 4,177E-04 6,204E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,177E-04 6,166E-03 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 17 10 1,000 4,177E-04 6,128E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 4,189E-04 6,108E-03 ! cellular component disassembly GO:0022411 86 48 2,000 4,458E-04 6,461E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 4,458E-04 6,423E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 4,458E-04 6,384E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,458E-04 6,347E-03 ! regulation of protein complex disassembly GO:0043244 113 49 2,000 4,738E-04 6,706E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 5,029E-04 7,076E-03 ! negative regulation of immune system process GO:0002683 95 50 2,000 5,029E-04 7,035E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 5,095E-04 7,086E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 5,095E-04 7,045E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,095E-04 7,005E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,095E-04 6,965E-03 ! DNA methylation GO:0006306 19 11 1,000 5,095E-04 6,926E-03 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 24 11 1,000 5,095E-04 6,887E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,332E-04 7,166E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 2,000 5,645E-04 7,546E-03 ! cartilage development GO:0051216 90 52 2,000 5,645E-04 7,504E-03 ! regulation of translational initiation GO:0006446 82 53 2,000 5,971E-04 7,893E-03 ! response to UV GO:0009411 104 53 2,000 5,971E-04 7,85E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,102E-04 7,979E-03 ! virus-host interaction GO:0019048 29 12 1,000 6,102E-04 7,936E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,102E-04 7,893E-03 ! hippocampus development GO:0021766 26 12 1,000 6,102E-04 7,851E-03 ! asymmetric protein localization GO:0008105 20 12 1,000 6,102E-04 7,809E-03 ! entry into host cell GO:0030260 32 12 1,000 6,102E-04 7,768E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! negative regulation of cytoskeleton organization GO:0051494 124 54 2,000 6,308E-04 7,988E-03 ! aging GO:0007568 103 55 2,000 6,657E-04 8,386E-03 ! response to X-ray GO:0010165 25 13 1,000 7,197E-04 9,018E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 7,197E-04 8,972E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,197E-04 8,925E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,197E-04 8,88E-03 ! embryonic placenta development GO:0001892 23 13 1,000 7,197E-04 8,834E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 7,392E-04 9,028E-03 ! DNA catabolic process GO:0006308 86 59 2,000 8,176E-04 9,935E-03 ! establishment of organelle localization GO:0051656 109 59 2,000 8,176E-04 9,885E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,379E-04 0,01008028 ! regulation of mRNA processing GO:0050684 24 14 1,000 8,379E-04 0,01003013 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 8,379E-04 9,98E-03 ! response to gamma radiation GO:0010332 28 14 1,000 8,379E-04 9,931E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 8,379E-04 9,883E-03 ! regulation of heart contraction GO:0008016 110 60 2,000 8,587E-04 0,01007829 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 8,587E-04 0,01002937 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 8,587E-04 9,981E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 9,011E-04 0,01042346 ! viral reproductive process GO:0022415 126 62 2,000 9,448E-04 0,0108768 ! regulation of homeostatic process GO:0032844 134 62 2,000 9,448E-04 0,010825 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 9,649E-04 0,01100259 ! G1/S transition checkpoint GO:0031575 40 15 1,000 9,649E-04 0,01095069 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 9,899E-04 0,01118123 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,084E-03 0,0121869 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,101E-03 0,01231566 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 1,101E-03 0,01225864 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,101E-03 0,01220215 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,101E-03 0,01214618 ! cell projection assembly GO:0030031 120 66 2,000 1,133E-03 0,01244799 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,184E-03 0,01294341 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 1,184E-03 0,01288484 ! viral reproduction GO:0016032 134 68 2,000 1,235E-03 0,01338897 ! limbic system development GO:0021761 36 17 1,000 1,245E-03 0,01343 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,245E-03 0,01337004 ! glycine metabolic process GO:0006544 28 17 1,000 1,245E-03 0,01331062 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,245E-03 0,01325172 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 1,245E-03 0,01319334 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,245E-03 0,01313548 ! cell cycle checkpoint GO:0000075 137 69 2,000 1,289E-03 0,01353952 ! negative regulation of cell size GO:0045792 134 69 2,000 1,289E-03 0,01348065 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,398E-03 0,01455622 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,398E-03 0,01449348 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,398E-03 0,01443127 ! lipid phosphorylation GO:0046834 35 19 1,000 1,559E-03 0,01602791 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,559E-03 0,0159597 ! pigmentation during development GO:0048066 41 19 1,000 1,559E-03 0,01589208 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,559E-03 0,01582502 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 34 19 1,000 1,559E-03 0,01575853 ! cellular pigmentation GO:0033059 36 19 1,000 1,559E-03 0,01569259 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,559E-03 0,01562721 ! organelle localization GO:0051640 136 74 2,000 1,577E-03 0,01574147 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 1,639E-03 0,01629333 ! regulation of catabolic process GO:0009894 161 76 2,000 1,702E-03 0,01685559 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,729E-03 0,01704464 ! cellular response to starvation GO:0009267 33 20 1,000 1,729E-03 0,01697507 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,729E-03 0,01690607 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 1,729E-03 0,01683762 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 1,729E-03 0,01676973 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,729E-03 0,01670238 ! negative regulation of translation GO:0017148 29 20 1,000 1,729E-03 0,01663557 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,729E-03 0,0165693 ! negative regulation of organelle organization GO:0010639 161 78 2,000 1,834E-03 0,01751101 ! protein oligomerization GO:0051259 139 78 2,000 1,834E-03 0,01744179 ! cell aging GO:0007569 44 21 1,000 1,907E-03 0,01806082 ! DNA modification GO:0006304 34 21 1,000 1,907E-03 0,01799 ! collagen catabolic process GO:0030574 28 21 1,000 1,907E-03 0,01791972 ! protein import into nucleus GO:0006606 158 80 2,000 1,972E-03 0,01846124 ! nuclear import GO:0051170 161 81 2,000 2,043E-03 0,01905459 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,093E-03 0,0194443 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,093E-03 0,01936951 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,093E-03 0,0192953 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,093E-03 0,01922165 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,093E-03 0,01914857 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,093E-03 0,01907603 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,093E-03 0,01900405 ! response to drug GO:0042493 143 82 2,000 2,116E-03 0,01914078 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,116E-03 0,01906909 ! negative regulation of growth GO:0045926 155 84 2,000 2,267E-03 0,02034976 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,288E-03 0,02046334 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,288E-03 0,02038755 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,288E-03 0,02031232 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 2,288E-03 0,02023764 ! barbed-end actin filament capping GO:0051016 50 23 1,000 2,288E-03 0,02016351 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 1,000 2,288E-03 0,02008992 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,288E-03 0,02001687 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,491E-03 0,02171384 ! pallium development GO:0021543 49 24 1,000 2,491E-03 0,02163546 ! protein localization in nucleus GO:0034504 176 87 2,000 2,505E-03 0,02167812 ! myelination GO:0042552 45 25 1,000 2,702E-03 0,02330142 ! vasculogenesis GO:0001570 46 25 1,000 2,702E-03 0,0232182 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,702E-03 0,02313558 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,702E-03 0,02305353 ! response to starvation GO:0042594 42 25 1,000 2,702E-03 0,02297207 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,702E-03 0,02289119 ! telomere organization GO:0032200 43 25 1,000 2,702E-03 0,02281087 GO:0000723|telomere maintenance, ! regulation of cell cycle process GO:0010564 149 90 2,000 2,758E-03 0,02319994 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 2,921E-03 0,02449039 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 2,921E-03 0,02440535 ! initiation of viral infection GO:0019059 57 26 1,000 2,921E-03 0,02432091 ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,921E-03 0,02423704 ! blastocyst development GO:0001824 49 26 1,000 2,921E-03 0,02415375 ! regulation of defense response GO:0031347 149 92 2,000 2,935E-03 0,02418239 ! regulation of T cell activation GO:0050863 158 94 2,000 3,119E-03 0,02561029 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,149E-03 0,02576814 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,149E-03 0,02568079 ! protein amino acid acylation GO:0043543 55 27 1,000 3,149E-03 0,02559403 ! fat cell differentiation GO:0045444 50 27 1,000 3,149E-03 0,02550785 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,149E-03 0,02542226 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 3,149E-03 0,02533723 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,149E-03 0,02525278 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 3,149E-03 0,02516888 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 3,149E-03 0,02508554 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 3,384E-03 0,0268721 ! dendrite development GO:0016358 59 28 1,000 3,384E-03 0,02678371 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 3,384E-03 0,02669589 ! regulation of pH GO:0006885 43 29 1,000 3,628E-03 0,02852243 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 3,628E-03 0,02842953 ! complement activation, classical pathway GO:0006958 48 29 1,000 3,628E-03 0,02833722 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,628E-03 0,02824552 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,628E-03 0,0281544 ! tissue homeostasis GO:0001894 48 29 1,000 3,628E-03 0,02806387 GO:0048871|multicellular organismal homeostasis, ! ensheathment of neurons GO:0007272 57 30 1,000 3,879E-03 0,02991206 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 50 30 1,000 3,879E-03 0,02981649 ! collagen metabolic process GO:0032963 45 31 1,000 4,138E-03 0,0317077 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 4,138E-03 0,03160704 ! iron ion homeostasis GO:0055072 54 31 1,000 4,138E-03 0,03150702 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 4,138E-03 0,03140763 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 4,138E-03 0,03130886 GO:0043433|negative regulation of transcription factor activity, ! response to ionizing radiation GO:0010212 65 32 1,000 4,405E-03 0,03322481 ! response to mechanical stimulus GO:0009612 57 32 1,000 4,405E-03 0,03312098 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 4,405E-03 0,0330178 ! peripheral nervous system development GO:0007422 64 32 1,000 4,405E-03 0,03291526 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,68E-03 0,03486047 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,68E-03 0,03475287 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 4,962E-03 0,03673768 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 4,962E-03 0,03662499 ! placenta development GO:0001890 53 34 1,000 4,962E-03 0,03651299 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,253E-03 0,03853063 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,253E-03 0,03841351 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 5,253E-03 0,03829711 ! telencephalon development GO:0021537 68 35 1,000 5,253E-03 0,03818141 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,253E-03 0,0380664 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,253E-03 0,03795209 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,551E-03 0,03998415 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 5,856E-03 0,04205855 ! negative regulation of DNA binding GO:0043392 68 37 1,000 5,856E-03 0,04193338 ! regulation of protein stability GO:0031647 73 37 1,000 5,856E-03 0,04180894 ! glycogen metabolic process GO:0005977 61 37 1,000 5,856E-03 0,04168525 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 6,169E-03 0,04378363 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,169E-03 0,04365486 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,169E-03 0,04352684 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,169E-03 0,04339956 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 62 38 1,000 6,169E-03 0,04327304 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 6,489E-03 0,04538866 ! ear morphogenesis GO:0042471 60 39 1,000 6,489E-03 0,0452571 ! regulation of action potential in neuron GO:0019228 73 39 1,000 6,489E-03 0,0451263 ! negative regulation of binding GO:0051100 72 40 1,000 6,817E-03 0,04726987 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 6,817E-03 0,04713404 ! T cell differentiation GO:0030217 81 41 1,000 7,153E-03 0,04931053 ! keratinocyte differentiation GO:0030216 62 41 1,000 7,153E-03 0,04916964 ! response to reactive oxygen species GO:0000302 67 42 1,000 7,495E-03 0,05137825 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 7,495E-03 0,05123229 ! energy reserve metabolic process GO:0006112 74 43 1,000 7,845E-03 0,05347227 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 7,845E-03 0,05332122 ! double-strand break repair GO:0006302 81 44 1,000 8,202E-03 0,05559182 ! biopolymer methylation GO:0043414 84 44 1,000 8,202E-03 0,05543566 ! B cell differentiation GO:0030183 107 44 1,000 8,202E-03 0,05528038 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 8,567E-03 0,05757487 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 8,567E-03 0,05741449 ! negative regulation of cell migration GO:0030336 115 46 1,000 8,938E-03 0,05973812 ! epidermal cell differentiation GO:0009913 68 46 1,000 8,938E-03 0,05957264 ! positive regulation of protein transport GO:0051222 72 46 1,000 8,938E-03 0,05940808 ! response to calcium ion GO:0051592 81 47 1,000 9,317E-03 0,06175411 ! methylation GO:0032259 90 47 1,000 9,317E-03 0,06158446 ! mitochondrial transport GO:0006839 82 48 1,000 9,703E-03 0,06395822 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,703E-03 0,06378347 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,01009544 0,06618429 ! regulation of action potential GO:0001508 95 49 1,000 0,01009544 0,06600444 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01009544 0,06582557 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,01009544 0,06564766 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01009544 0,06547071 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01049513 0,0678798 ! viral infectious cycle GO:0019058 99 51 1,000 0,01090174 0,07032062 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,01090174 0,07013259 ! regulation of cell shape GO:0008360 125 51 1,000 0,01090174 0,06994557 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01131523 0,07240543 ! positive regulation of growth GO:0045927 90 52 1,000 0,01131523 0,07221337 ! synapse organization GO:0050808 85 52 1,000 0,01131523 0,07202233 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,01173555 0,0745006 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,01173555 0,07430455 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01173555 0,07410952 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,01173555 0,07391552 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,0125965 0,07913102 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,0125965 0,07892495 ! heart morphogenesis GO:0003007 97 55 1,000 0,0125965 0,07871995 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,0125965 0,07851601 ! regulation of actin filament length GO:0030832 105 56 1,000 0,01303704 0,08105201 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01303704 0,08084311 ! muscle fiber development GO:0048747 112 57 1,000 0,01348424 0,08340123 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,01348424 0,08318739 ! lipid modification GO:0030258 97 57 1,000 0,01348424 0,08297463 ! regulation of cellular component size GO:0032535 109 59 1,000 0,01439841 0,08837391 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01439841 0,08814904 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01439841 0,08792531 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,01439841 0,08770272 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,0148653 0,09031793 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01534574 0,09300212 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01534574 0,09276845 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01534574 0,09253595 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01534574 0,09230461 ! neuron fate determination GO:0048664 7 5 0,000 0,01534574 0,09207442 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01534574 0,09184538 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01534574 0,09161748 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01534574 0,0913907 ! polyol transport GO:0015791 12 5 0,000 0,01534574 0,09116504 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01534574 0,0909405 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01534574 0,09071706 ! response to superoxide GO:0000303 10 5 0,000 0,01534574 0,09049471 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01534574 0,09027345 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01534574 0,09005328 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01534574 0,08983417 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01534574 0,08961612 ! female meiosis GO:0007143 7 5 0,000 0,01534574 0,08939914 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01534574 0,0891832 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01534574 0,0889683 ! cobalt ion transport GO:0006824 11 5 0,000 0,01534574 0,08875443 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01534574 0,08854159 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01534574 0,08832977 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01534574 0,08811896 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01534574 0,08790915 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01534574 0,08770034 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01534574 0,08749252 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01534574 0,08728568 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01534574 0,08707982 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01534574 0,08687492 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01534574 0,08667099 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01534574 0,08646802 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01534574 0,08626599 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01534574 0,0860649 ! negative chemotaxis GO:0050919 14 5 0,000 0,01534574 0,08586475 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01534574 0,08566553 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01534574 0,08546723 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01534574 0,08526985 ! behavioral response to pain GO:0048266 9 5 0,000 0,01534574 0,08507337 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01534574 0,0848778 ! Notch receptor processing GO:0007220 8 5 0,000 0,01534574 0,08468313 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01534574 0,08448934 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01534574 0,08429644 ! micturition GO:0060073 9 5 0,000 0,01534574 0,08410443 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01534574 0,08391328 ! copulation GO:0007620 9 5 0,000 0,01534574 0,083723 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01534574 0,08353358 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01534574 0,08334502 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01534574 0,0831573 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01534574 0,08297043 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01534574 0,0827844 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01534574 0,0825992 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01534574 0,08241483 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01534574 0,08223128 ! grooming behavior GO:0007625 6 5 0,000 0,01534574 0,08204854 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01534574 0,08186661 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01534574 0,08168549 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01534574 0,08150517 ! response to protozoan GO:0001562 10 5 0,000 0,01534574 0,08132565 ! lymph vessel development GO:0001945 10 5 0,000 0,01534574 0,08114691 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01534574 0,08096895 ! endochondral ossification GO:0001958 16 5 0,000 0,01534574 0,08079178 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01534574 0,08061538 ! parathyroid gland development GO:0060017 13 5 0,000 0,01534574 0,08043974 ! anagen GO:0042640 6 5 0,000 0,01534574 0,08026488 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01534574 0,08009077 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01534574 0,07991741 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01534574 0,0797448 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01534574 0,07957294 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01534574 0,07940181 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01534574 0,07923142 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01534574 0,07906176 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01534574 0,07889283 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01534574 0,07872461 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01534574 0,07855711 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01534574 0,07839032 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01534574 0,07822424 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01534574 0,07805886 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01534574 0,07789418 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01534574 0,0777302 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01534574 0,0775669 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01534574 0,07740428 ! histidine catabolic process GO:0006548 6 5 0,000 0,01534574 0,07724235 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01534574 0,07708109 ! microvillus organization GO:0032528 7 5 0,000 0,01534574 0,07692051 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01534574 0,07676059 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01534574 0,07660133 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01534574 0,07644274 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01534574 0,0762848 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01534574 0,07612751 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01534574 0,07597087 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01534574 0,07581487 ! polyol catabolic process GO:0046174 7 5 0,000 0,01534574 0,07565951 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01534574 0,07550479 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01534574 0,0753507 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01534574 0,07519724 ! muscle cell migration GO:0014812 8 5 0,000 0,01534574 0,0750444 ! mitochondrial fission GO:0000266 8 5 0,000 0,01534574 0,07489218 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01534574 0,07474057 ! mRNA transcription GO:0009299 9 5 0,000 0,01534574 0,07458958 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01534574 0,0744392 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01534574 0,07428942 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01534574 0,07414025 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01534574 0,07399167 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01534574 0,07384369 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01534574 0,07369629 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01534574 0,07354949 ! response to food GO:0032094 6 5 0,000 0,01534574 0,07340327 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01534574 0,07325762 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01534574 0,07311256 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01534574 0,07296807 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01534574 0,07282415 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01534574 0,07268079 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01534574 0,072538 ! forebrain neuron development GO:0021884 13 5 0,000 0,01534574 0,07239577 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01534574 0,0722541 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01534574 0,07211297 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01534574 0,0719724 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01534574 0,07183238 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01534574 0,0716929 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01534574 0,07155396 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01534574 0,07141556 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01534574 0,07127769 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01534574 0,07114035 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01534574 0,07100354 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01534574 0,07086726 ! basic amino acid transport GO:0015802 11 5 0,000 0,01534574 0,0707315 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01534574 0,07059626 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01534574 0,07046153 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01534574 0,07032732 ! depyrimidination GO:0045008 10 5 0,000 0,01534574 0,07019362 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01534574 0,07006042 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01534574 0,06992773 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01534574 0,06979554 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01534574 0,06966385 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01534574 0,06953266 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01534574 0,06940196 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01534574 0,06927175 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01534574 0,06914203 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01534574 0,06901279 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01534574 0,06888404 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01534574 0,06875576 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01534574 0,06862796 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01534574 0,06850064 ! response to arsenic GO:0046685 10 5 0,000 0,01534574 0,06837378 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01534574 0,0682474 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01534574 0,06812148 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01534574 0,06799603 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01534574 0,06787103 ! response to cadmium ion GO:0046686 7 5 0,000 0,01534574 0,0677465 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01534574 0,06762242 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01534574 0,0674988 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01534574 0,06737563 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01534574 0,0672529 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01534574 0,06713062 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01534574 0,06700879 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01534574 0,0668874 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01534574 0,06676644 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01534574 0,06664593 ! neural tube patterning GO:0021532 7 5 0,000 0,01534574 0,06652584 ! embryonic cleavage GO:0040016 6 5 0,000 0,01534574 0,06640619 ! peroxisome fission GO:0016559 5 5 0,000 0,01534574 0,06628697 ! histone demethylation GO:0016577 10 5 0,000 0,01534574 0,06616818 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01534574 0,06604981 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01534574 0,06593186 ! metaphase plate congression GO:0051310 7 5 0,000 0,01534574 0,06581434 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01534574 0,06569723 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01534574 0,06558054 ! enteric nervous system development GO:0048484 8 5 0,000 0,01534574 0,06546426 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01534574 0,06534839 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01534574 0,06523294 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01534574 0,06511789 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01534574 0,06500324 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01534574 0,064889 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01534574 0,06477516 ! plasminogen activation GO:0031639 5 5 0,000 0,01534574 0,06466172 ! B cell homeostasis GO:0001782 13 5 0,000 0,01534574 0,06454868 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01534574 0,06443603 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01534574 0,06432377 ! metaphase GO:0051323 8 5 0,000 0,01534574 0,0642119 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01534574 0,06410042 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01534574 0,06398933 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01534574 0,06387862 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01534574 0,0637683 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01534574 0,06365835 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01534574 0,06354878 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01534574 0,06343959 ! response to redox state GO:0051775 5 5 0,000 0,01534574 0,06333078 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01534574 0,06322233 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01534574 0,06311426 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01534574 0,06300656 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01534574 0,06289922 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01534574 0,06279225 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01534574 0,06268564 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01534574 0,06257939 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01534574 0,06247351 ! striatum development GO:0021756 9 5 0,000 0,01534574 0,06236798 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01534574 0,0622628 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01534574 0,06215798 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01534574 0,06205352 ! glial cell migration GO:0008347 11 5 0,000 0,01534574 0,0619494 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01534574 0,06184563 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01534574 0,06174221 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01534574 0,06163914 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01534574 0,0615364 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01534574 0,06143401 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01534574 0,06133196 ! neuroprotection GO:0043526 6 5 0,000 0,01534574 0,06123025 ! neural plate development GO:0001840 8 5 0,000 0,01534574 0,06112888 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01534574 0,06102784 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01534574 0,06092713 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01534574 0,06082676 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01534574 0,06072672 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01534574 0,060627 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01534574 0,06052761 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01534574 0,06042855 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01534574 0,06032981 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01534574 0,06023139 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01534574 0,06013329 ! spindle assembly GO:0051225 6 5 0,000 0,01534574 0,06003552 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01534574 0,05993806 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01534574 0,05984091 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01534574 0,05974408 ! drug metabolic process GO:0017144 6 5 0,000 0,01534574 0,05964757 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01534574 0,05955136 ! organ regeneration GO:0031100 7 5 0,000 0,01534574 0,05945546 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01534574 0,05935988 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01534574 0,0592646 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01534574 0,05916962 ! ear development GO:0043583 103 62 1,000 0,01581845 0,06089471 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,01630464 0,06266606 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,01679716 0,06445611 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,01679716 0,06435347 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 1,000 0,01679716 0,06425116 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0183124 0,06993592 ! adaptive immune response GO:0002250 119 67 1,000 0,0183124 0,06982509 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,0183124 0,06971461 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01838681 0,06988731 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01838681 0,06977708 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01838681 0,0696672 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01838681 0,06955766 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01838681 0,06944846 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01838681 0,06933961 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01838681 0,06923109 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01838681 0,06912292 ! sleep GO:0030431 13 6 0,000 0,01838681 0,06901508 ! response to oxygen radical GO:0000305 11 6 0,000 0,01838681 0,06890758 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01838681 0,06880042 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01838681 0,06869359 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01838681 0,06858708 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01838681 0,06848091 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01838681 0,06837507 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01838681 0,06826955 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01838681 0,06816436 ! forebrain regionalization GO:0021871 8 6 0,000 0,01838681 0,06805949 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01838681 0,06795494 ! male meiosis GO:0007140 7 6 0,000 0,01838681 0,06785072 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01838681 0,06774681 ! response to zinc ion GO:0010043 9 6 0,000 0,01838681 0,06764322 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01838681 0,06753995 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01838681 0,067437 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01838681 0,06733435 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01838681 0,06723202 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01838681 0,06713 ! malate metabolic process GO:0006108 11 6 0,000 0,01838681 0,06702829 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01838681 0,06692688 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01838681 0,06682578 ! protein refolding GO:0042026 15 6 0,000 0,01838681 0,06672499 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01838681 0,0666245 ! opsonization GO:0008228 8 6 0,000 0,01838681 0,06652431 ! mating behavior GO:0007617 7 6 0,000 0,01838681 0,06642443 ! neuron remodeling GO:0016322 15 6 0,000 0,01838681 0,06632484 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01838681 0,06622555 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01838681 0,06612656 ! equilibrioception GO:0050957 14 6 0,000 0,01838681 0,06602786 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01838681 0,06592946 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01838681 0,06583135 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01838681 0,06573353 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01838681 0,06563601 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01838681 0,06553877 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01838681 0,06544182 ! toxin metabolic process GO:0009404 11 6 0,000 0,01838681 0,06534515 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01838681 0,06524877 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01838681 0,06515268 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01838681 0,06505687 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01838681 0,06496133 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01838681 0,06486608 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01838681 0,06477111 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01838681 0,06467642 ! thymic T cell selection GO:0045061 12 6 0,000 0,01838681 0,064582 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01838681 0,06448786 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01838681 0,06439399 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01838681 0,06430039 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01838681 0,06420707 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01838681 0,06411401 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01838681 0,06402123 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01838681 0,06392871 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01838681 0,06383646 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01838681 0,06374448 ! hyperosmotic response GO:0006972 9 6 0,000 0,01838681 0,06365276 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01838681 0,06356131 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01838681 0,06347011 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01838681 0,06337918 ! urea metabolic process GO:0019627 7 6 0,000 0,01838681 0,06328851 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01838681 0,0631981 ! neutrophil activation GO:0042119 8 6 0,000 0,01838681 0,06310794 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01838681 0,06301805 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01838681 0,06292841 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01838681 0,06283902 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01838681 0,06274989 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01838681 0,062661 ! neuron apoptosis GO:0051402 9 6 0,000 0,01838681 0,06257237 ! nucleoside salvage GO:0043174 9 6 0,000 0,01838681 0,062484 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01838681 0,06239587 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01838681 0,06230798 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01838681 0,06222035 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01838681 0,06213296 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01838681 0,06204582 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01838681 0,06195892 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01838681 0,06187226 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01838681 0,06178585 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01838681 0,06169968 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01838681 0,06161375 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01838681 0,06152805 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01838681 0,0614426 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01838681 0,06135738 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01838681 0,06127239 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01838681 0,06118765 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01838681 0,06110313 ! monocyte differentiation GO:0030224 12 6 0,000 0,01838681 0,06101885 ! neural nucleus development GO:0048857 14 6 0,000 0,01838681 0,06093481 ! response to UV-C GO:0010225 11 6 0,000 0,01838681 0,06085099 ! astrocyte development GO:0014002 15 6 0,000 0,01838681 0,0607674 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01838681 0,06068405 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01838681 0,06060092 ! interaction with symbiont GO:0051702 13 6 0,000 0,01838681 0,06051802 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01838681 0,06043534 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01838681 0,06035289 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01838681 0,06027067 ! response to copper ion GO:0046688 10 6 0,000 0,01838681 0,06018867 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01838681 0,06010689 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01838681 0,06002533 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01838681 0,059944 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01838681 0,05986288 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01838681 0,05978199 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01838681 0,05970131 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01838681 0,05962085 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01838681 0,0595406 ! hair follicle maturation GO:0048820 7 6 0,000 0,01838681 0,05946058 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01838681 0,05938076 ! Schwann cell development GO:0014044 15 6 0,000 0,01838681 0,05930116 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01838681 0,05922178 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01838681 0,05914261 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01838681 0,05906364 ! subpallium development GO:0021544 10 6 0,000 0,01838681 0,05898489 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01838681 0,05890635 ! histone ubiquitination GO:0016574 8 6 0,000 0,01838681 0,05882802 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01838681 0,05874989 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01838681 0,05867197 ! G2 phase GO:0051319 16 6 0,000 0,01838681 0,05859426 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01838681 0,05851676 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01838681 0,05843946 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01838681 0,05836236 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01838681 0,05828547 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01838681 0,05820878 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01838681 0,05813229 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01838681 0,058056 ! receptor internalization GO:0031623 10 6 0,000 0,01838681 0,05797991 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01838681 0,05790402 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01838681 0,05782833 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01838681 0,05775283 ! protein deubiquitination GO:0016579 14 6 0,000 0,01838681 0,05767753 ! protein destabilization GO:0031648 9 6 0,000 0,01838681 0,05760243 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01838681 0,05752753 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01838681 0,05745282 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01838681 0,0573783 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01838681 0,05730398 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01838681 0,05722984 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01838681 0,0571559 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01838681 0,05708215 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01838681 0,05700859 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01838681 0,05693522 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01838681 0,05686204 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01838681 0,05678905 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01838681 0,05671624 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01838681 0,05664362 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01838681 0,05657119 ! catecholamine transport GO:0051937 9 6 0,000 0,01838681 0,05649894 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01838681 0,05642687 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01838681 0,05635499 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01838681 0,05628329 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01838681 0,05621178 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01838681 0,05614044 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01838681 0,05606929 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01838681 0,05599832 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01838681 0,05592752 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01838681 0,05585691 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01838681 0,05578647 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,01882988 0,05705882 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,01882988 0,05698704 ! antigen processing and presentation GO:0019882 104 69 1,000 0,0193535 0,05849815 ! amine catabolic process GO:0009310 117 71 1,000 0,02041897 0,06164121 ! humoral immune response GO:0006959 109 71 1,000 0,02041897 0,06156396 ! B cell activation GO:0042113 160 71 1,000 0,02041897 0,06148691 ! acute inflammatory response GO:0002526 113 72 1,000 0,02096074 0,06303942 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02096074 0,06296072 ! tRNA transcription GO:0009304 14 7 0,000 0,0214186 0,06425579 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0214186 0,06417577 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0214186 0,06409594 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0214186 0,06401632 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0214186 0,0639369 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0214186 0,06385767 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0214186 0,06377864 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0214186 0,0636998 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0214186 0,06362116 ! prostate gland development GO:0030850 13 7 0,000 0,0214186 0,06354271 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0214186 0,06346446 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0214186 0,0633864 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0214186 0,06330853 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0214186 0,06323085 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0214186 0,06315336 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0214186 0,06307606 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0214186 0,06299895 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0214186 0,06292203 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0214186 0,06284529 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0214186 0,06276874 ! glycolipid transport GO:0046836 10 7 0,000 0,0214186 0,06269238 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0214186 0,06261621 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,0214186 0,06254022 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,0214186 0,06246441 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0214186 0,06238879 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0214186 0,06231335 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0214186 0,06223809 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0214186 0,06216302 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0214186 0,06208812 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0214186 0,06201341 ! mRNA stabilization GO:0048255 18 7 0,000 0,0214186 0,06193887 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0214186 0,06186451 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0214186 0,06179034 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0214186 0,06171633 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0214186 0,06164251 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0214186 0,06156886 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0214186 0,06149539 ! lipoprotein transport GO:0042953 14 7 0,000 0,0214186 0,0614221 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0214186 0,06134898 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0214186 0,06127603 ! rhythmic behavior GO:0007622 15 7 0,000 0,0214186 0,06120325 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0214186 0,06113065 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0214186 0,06105822 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0214186 0,06098596 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0214186 0,06091388 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0214186 0,06084196 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0214186 0,06077021 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0214186 0,06069863 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0214186 0,06062722 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0214186 0,06055598 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0214186 0,06048491 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0214186 0,060414 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0214186 0,06034325 ! spinal cord patterning GO:0021511 13 7 0,000 0,0214186 0,06027268 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0214186 0,06020227 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0214186 0,06013202 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0214186 0,06006193 ! adrenal gland development GO:0030325 17 7 0,000 0,0214186 0,05999201 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0214186 0,05992226 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0214186 0,05985266 ! ovulation GO:0030728 9 7 0,000 0,0214186 0,05978322 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0214186 0,05971395 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0214186 0,05964484 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0214186 0,05957588 ! microtubule nucleation GO:0007020 20 7 0,000 0,0214186 0,05950709 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0214186 0,05943845 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0214186 0,05936998 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0214186 0,05930166 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0214186 0,05923349 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0214186 0,05916549 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0214186 0,05909764 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0214186 0,05902994 ! galactose metabolic process GO:0006012 13 7 0,000 0,0214186 0,0589624 ! vesicle fusion GO:0006906 17 7 0,000 0,0214186 0,05889502 ! response to dietary excess GO:0002021 8 7 0,000 0,0214186 0,05882778 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0214186 0,05876071 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0214186 0,05869378 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0214186 0,05862701 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0214186 0,05856039 ! organ growth GO:0035265 15 7 0,000 0,0214186 0,05849392 ! purine salvage GO:0043101 10 7 0,000 0,0214186 0,0584276 ! nucleoside transport GO:0015858 8 7 0,000 0,0214186 0,05836143 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0214186 0,05829541 ! parturition GO:0007567 14 7 0,000 0,0214186 0,05822954 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0214186 0,05816381 ! rRNA modification GO:0000154 14 7 0,000 0,0214186 0,05809824 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0214186 0,05803281 ! spindle checkpoint GO:0031577 15 7 0,000 0,0214186 0,05796754 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0214186 0,0579024 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0214186 0,05783742 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0214186 0,05777258 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0214186 0,05770788 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0214186 0,05764333 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0214186 0,05757893 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0214186 0,05751466 ! fibrinolysis GO:0042730 10 7 0,000 0,0214186 0,05745055 ! eating behavior GO:0042755 7 7 0,000 0,0214186 0,05738657 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0214186 0,05732274 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0214186 0,05725904 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0214186 0,05719549 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0214186 0,05713208 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0214186 0,05706881 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0214186 0,05700569 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0214186 0,0569427 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0214186 0,05687985 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0214186 0,05681713 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0214186 0,05675456 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0214186 0,05669212 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0214186 0,05662982 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0214186 0,05656766 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0214186 0,05650564 ! regulation of meiosis GO:0040020 12 7 0,000 0,0214186 0,05644375 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0214186 0,05638199 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0214186 0,05632037 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0214186 0,05625889 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0214186 0,05619754 ! transcription termination GO:0006353 13 7 0,000 0,0214186 0,05613632 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0214186 0,05607523 ! anaphase GO:0051322 17 7 0,000 0,0214186 0,05601428 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0214186 0,05595346 ! axonal fasciculation GO:0007413 18 7 0,000 0,0214186 0,05589278 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0214186 0,05583222 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0214186 0,0557718 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0214186 0,0557115 ! diuresis GO:0030146 12 7 0,000 0,0214186 0,05565134 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0214186 0,0555913 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0214186 0,0555314 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0214186 0,05547163 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0214186 0,05541198 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0214186 0,05535246 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0214186 0,05529307 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0214186 0,0552338 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0214186 0,05517467 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0214186 0,05511566 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0214186 0,05505677 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0214186 0,05499801 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0214186 0,05493938 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0214186 0,05488087 ! lymph node development GO:0048535 10 7 0,000 0,0214186 0,05482249 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0214186 0,05476423 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0214186 0,05470609 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0214186 0,05464808 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0214186 0,05459019 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0214186 0,05453242 ! adult feeding behavior GO:0008343 9 7 0,000 0,0214186 0,05447478 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0214186 0,05441725 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0214186 0,05435985 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0214186 0,05430257 ! muscle adaptation GO:0043500 14 7 0,000 0,0214186 0,05424541 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0214186 0,05418837 ! retina homeostasis GO:0001895 12 7 0,000 0,0214186 0,05413145 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0214186 0,05407465 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0214186 0,05401797 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0214186 0,0539614 ! protein prenylation GO:0018342 18 7 0,000 0,0214186 0,05390496 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0214186 0,05384863 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0214186 0,05379242 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0214186 0,05373633 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,02150847 0,0539056 ! axon guidance GO:0007411 139 73 1,000 0,02150847 0,05384951 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02206213 0,05517826 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,02206213 0,05512096 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,02206213 0,05506378 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,02262167 0,0564018 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02262167 0,05634342 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,02375825 0,05911307 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02444111 0,0607493 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02444111 0,06068661 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02444111 0,06062404 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02444111 0,06056161 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02444111 0,0604993 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02444111 0,06043712 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02444111 0,06037507 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02444111 0,06031315 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02444111 0,06025135 ! meiotic prophase I GO:0007128 13 8 0,000 0,02444111 0,06018968 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02444111 0,06012814 ! oligopeptide transport GO:0006857 15 8 0,000 0,02444111 0,06006672 ! UTP metabolic process GO:0046051 8 8 0,000 0,02444111 0,06000543 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02444111 0,05994426 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02444111 0,05988322 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02444111 0,0598223 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02444111 0,05976151 ! succinate metabolic process GO:0006105 14 8 0,000 0,02444111 0,05970083 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02444111 0,05964029 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02444111 0,05957986 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02444111 0,05951956 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02444111 0,05945938 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02444111 0,05939932 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02444111 0,05933938 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02444111 0,05927956 ! reflex GO:0060004 16 8 0,000 0,02444111 0,05921986 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02444111 0,05916028 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02444111 0,05910083 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02444111 0,05904149 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02444111 0,05898227 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02444111 0,05892317 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02444111 0,05886419 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02444111 0,05880532 ! pigment granule organization GO:0048753 16 8 0,000 0,02444111 0,05874658 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02444111 0,05868795 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02444111 0,05862943 ! histidine metabolic process GO:0006547 16 8 0,000 0,02444111 0,05857104 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02444111 0,05851276 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02444111 0,05845459 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02444111 0,05839655 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02444111 0,05833861 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02444111 0,0582808 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02444111 0,05822309 ! melanin metabolic process GO:0006582 15 8 0,000 0,02444111 0,0581655 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02444111 0,05810803 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02444111 0,05805066 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02444111 0,05799341 ! macrophage activation GO:0042116 12 8 0,000 0,02444111 0,05793628 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02444111 0,05787925 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02444111 0,05782234 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02444111 0,05776554 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02444111 0,05770885 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02444111 0,05765228 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02444111 0,05759581 ! osteoblast development GO:0002076 16 8 0,000 0,02444111 0,05753945 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02444111 0,05748321 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02444111 0,05742707 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02444111 0,05737105 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02444111 0,05731513 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02444111 0,05725932 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02444111 0,05720362 ! response to UV-B GO:0010224 16 8 0,000 0,02444111 0,05714803 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02444111 0,05709255 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02444111 0,05703717 ! intermediate filament organization GO:0045109 12 8 0,000 0,02444111 0,0569819 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02444111 0,05692674 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02444111 0,05687168 ! cellular extravasation GO:0045123 12 8 0,000 0,02444111 0,05681674 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02444111 0,05676189 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02444111 0,05670716 ! response to antibiotic GO:0046677 11 8 0,000 0,02444111 0,05665253 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02444111 0,056598 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02444111 0,05654358 ! DNA topological change GO:0006265 12 8 0,000 0,02444111 0,05648926 ! response to tropane GO:0014073 15 8 0,000 0,02444111 0,05643505 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02444111 0,05638094 ! melanosome transport GO:0032402 13 8 0,000 0,02444111 0,05632694 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02444111 0,05627304 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02444111 0,05621924 ! mast cell activation GO:0045576 14 8 0,000 0,02444111 0,05616554 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02444111 0,05611195 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02444111 0,05605846 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02444111 0,05600507 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02444111 0,05595178 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02444111 0,0558986 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02444111 0,05584551 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02444111 0,05579253 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02444111 0,05573964 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02444111 0,05568686 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02444111 0,05563417 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02444111 0,05558159 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02444111 0,05552911 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02444111 0,05547672 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02444111 0,05542443 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02444111 0,05537224 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02444111 0,05532015 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02444111 0,05526816 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02444111 0,05521626 ! hormone catabolic process GO:0042447 17 8 0,000 0,02444111 0,05516447 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02444111 0,05511277 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02444111 0,05506116 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02444111 0,05500966 ! ATP catabolic process GO:0006200 11 8 0,000 0,02444111 0,05495825 ! blastocyst growth GO:0001832 19 8 0,000 0,02444111 0,05490693 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02444111 0,05485571 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02444111 0,05480459 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02444111 0,05475356 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02444111 0,05470263 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02444111 0,05465179 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02444111 0,05460104 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02444111 0,05455039 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02444111 0,05449984 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02444111 0,05444937 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02444111 0,054399 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02444111 0,05434873 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02444111 0,05429854 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02444111 0,05424845 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02444111 0,05419845 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02444111 0,05414855 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02444111 0,05409873 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02491787 0,05510331 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02491787 0,05505271 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,02491787 0,05500221 ! response to metal ion GO:0010038 140 80 1,000 0,02550623 0,0562493 ! T cell activation GO:0042110 168 81 1,000 0,02610023 0,05750655 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02610023 0,05745394 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,02610023 0,05740142 ! axon extension GO:0048675 15 9 0,000 0,0274544 0,06032446 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0274544 0,06026942 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0274544 0,06021448 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0274544 0,06015964 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0274544 0,0601049 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0274544 0,06005026 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0274544 0,05999572 ! phosphate transport GO:0006817 19 9 0,000 0,0274544 0,05994127 ! reproductive behavior GO:0019098 19 9 0,000 0,0274544 0,05988693 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0274544 0,05983268 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0274544 0,05977854 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0274544 0,05972449 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0274544 0,05967054 ! GTP metabolic process GO:0046039 9 9 0,000 0,0274544 0,05961668 ! RNA methylation GO:0001510 15 9 0,000 0,0274544 0,05956293 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0274544 0,05950927 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0274544 0,0594557 ! artery development GO:0060840 24 9 0,000 0,0274544 0,05940223 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0274544 0,05934886 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0274544 0,05929559 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0274544 0,05924241 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0274544 0,05918932 ! chemosensory behavior GO:0007635 20 9 0,000 0,0274544 0,05913633 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0274544 0,05908344 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0274544 0,05903064 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0274544 0,05897793 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0274544 0,05892532 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0274544 0,0588728 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0274544 0,05882038 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0274544 0,05876805 ! protein targeting to ER GO:0045047 22 9 0,000 0,0274544 0,05871581 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0274544 0,05866366 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0274544 0,05861161 ! T cell selection GO:0045058 23 9 0,000 0,0274544 0,05855965 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0274544 0,05850778 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0274544 0,058456 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0274544 0,05840432 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0274544 0,05835272 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0274544 0,05830122 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0274544 0,05824981 ! mannose metabolic process GO:0006013 13 9 0,000 0,0274544 0,05819849 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0274544 0,05814726 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0274544 0,05809612 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0274544 0,05804507 ! receptor clustering GO:0043113 18 9 0,000 0,0274544 0,0579941 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0274544 0,05794323 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0274544 0,05789245 ! ruffle organization GO:0031529 15 9 0,000 0,0274544 0,05784175 ! retinol metabolic process GO:0042572 18 9 0,000 0,0274544 0,05779115 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0274544 0,05774063 ! behavioral fear response GO:0001662 22 9 0,000 0,0274544 0,0576902 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0274544 0,05763986 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0274544 0,05758961 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0274544 0,05753945 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,0274544 0,05748937 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0274544 0,05743938 ! segment specification GO:0007379 13 9 0,000 0,0274544 0,05738947 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0274544 0,05733966 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0274544 0,05728993 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0274544 0,05724028 ! response to amine stimulus GO:0014075 13 9 0,000 0,0274544 0,05719072 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0274544 0,05714125 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0274544 0,05709186 ! erythrocyte development GO:0048821 15 9 0,000 0,0274544 0,05704256 ! gas homeostasis GO:0033483 16 9 0,000 0,0274544 0,05699334 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0274544 0,05694421 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0274544 0,05689516 ! renal water homeostasis GO:0003091 14 9 0,000 0,0274544 0,0568462 ! postreplication repair GO:0006301 22 9 0,000 0,0274544 0,05679732 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0274544 0,05674853 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0274544 0,05669981 ! icosanoid secretion GO:0032309 15 9 0,000 0,0274544 0,05665119 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0274544 0,05660264 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0274544 0,05655418 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0274544 0,0565058 ! regulation of cell division GO:0051302 15 9 0,000 0,0274544 0,05645751 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0274544 0,05640929 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0274544 0,05636116 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0274544 0,05631312 ! sterol catabolic process GO:0016127 11 9 0,000 0,0274544 0,05626515 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0274544 0,05621726 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0274544 0,05616946 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0274544 0,05612174 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0274544 0,0560741 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0274544 0,05602653 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0274544 0,05597905 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0274544 0,05593165 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0274544 0,05588434 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0274544 0,0558371 ! purine base metabolic process GO:0006144 21 9 0,000 0,0274544 0,05578994 ! pigment granule transport GO:0051904 17 9 0,000 0,0274544 0,05574286 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0274544 0,05569586 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0274544 0,05564893 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0274544 0,05560209 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0274544 0,05555533 ! mitochondrion localization GO:0051646 15 9 0,000 0,0274544 0,05550864 ! regulation of ligase activity GO:0051340 142 84 1,000 0,02791569 0,05639391 ! response to unfolded protein GO:0006986 131 85 1,000 0,02853186 0,05759032 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,02853186 0,05754204 ! response to inorganic substance GO:0010035 153 86 1,000 0,02915348 0,05874646 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,02978051 0,05995976 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03041291 0,06118182 ! gland development GO:0048732 206 88 1,000 0,03041291 0,06113071 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03045848 0,0611712 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03045848 0,06112018 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03045848 0,06106924 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03045848 0,0610184 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03045848 0,06096763 ! synapsis GO:0007129 13 10 0,000 0,03045848 0,06091695 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03045848 0,06086636 ! N-glycan processing GO:0006491 20 10 0,000 0,03045848 0,06081584 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03045848 0,06076542 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03045848 0,06071507 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03045848 0,06066481 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03045848 0,06061463 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03045848 0,06056454 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03045848 0,06051453 ! androgen metabolic process GO:0008209 17 10 0,000 0,03045848 0,0604646 ! phospholipid efflux GO:0033700 16 10 0,000 0,03045848 0,06041475 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03045848 0,06036499 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03045848 0,0603153 ! lung alveolus development GO:0048286 26 10 0,000 0,03045848 0,0602657 ! pathogenesis GO:0009405 13 10 0,000 0,03045848 0,06021618 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03045848 0,06016674 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03045848 0,06011739 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03045848 0,06006811 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03045848 0,06001891 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03045848 0,0599698 ! endoderm development GO:0007492 16 10 0,000 0,03045848 0,05992076 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03045848 0,05987181 ! arginine catabolic process GO:0006527 13 10 0,000 0,03045848 0,05982293 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03045848 0,05977414 ! proline metabolic process GO:0006560 13 10 0,000 0,03045848 0,05972542 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03045848 0,05967679 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03045848 0,05962823 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03045848 0,05957975 ! V(D)J recombination GO:0033151 28 10 0,000 0,03045848 0,05953135 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03045848 0,05948303 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03045848 0,05943479 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03045848 0,05938662 ! B cell proliferation GO:0042100 18 10 0,000 0,03045848 0,05933854 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03045848 0,05929053 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03045848 0,0592426 ! multicellular organism growth GO:0035264 18 10 0,000 0,03045848 0,05919474 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03045848 0,05914697 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03045848 0,05909927 ! epithelial cell development GO:0002064 20 10 0,000 0,03045848 0,05905165 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03045848 0,0590041 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03045848 0,05895663 ! macroautophagy GO:0016236 17 10 0,000 0,03045848 0,05890924 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03045848 0,05886192 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03045848 0,05881468 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03045848 0,05876752 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03045848 0,05872043 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03045848 0,05867341 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03045848 0,05862647 ! brain morphogenesis GO:0048854 23 10 0,000 0,03045848 0,05857961 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03045848 0,05853282 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03045848 0,05848611 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03045848 0,05843947 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03045848 0,0583929 ! response to dsRNA GO:0043331 20 10 0,000 0,03045848 0,05834641 ! DNA ligation GO:0006266 19 10 0,000 0,03045848 0,05829999 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03045848 0,05825365 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03045848 0,05820738 ! melanosome localization GO:0032400 16 10 0,000 0,03045848 0,05816118 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03045848 0,05811506 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03045848 0,05806901 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03045848 0,05802303 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03045848 0,05797713 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03045848 0,0579313 ! mRNA cleavage GO:0006379 17 10 0,000 0,03045848 0,05788554 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03045848 0,05783985 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03045848 0,05779424 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03045848 0,05774869 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03045848 0,05770322 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03045848 0,05765782 ! salivary gland development GO:0007431 27 10 0,000 0,03045848 0,05761249 ! prophase GO:0051324 15 10 0,000 0,03045848 0,05756724 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03045848 0,05752205 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03045848 0,05747694 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03045848 0,05743189 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03045848 0,05738692 ! midbrain development GO:0030901 13 10 0,000 0,03045848 0,05734201 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03045848 0,05729718 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03045848 0,05725242 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03045848 0,05720772 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03045848 0,0571631 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03045848 0,05711854 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03045848 0,05707406 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03045848 0,05702964 ! detection of calcium ion GO:0005513 23 10 0,000 0,03045848 0,0569853 ! oocyte development GO:0048599 17 10 0,000 0,03045848 0,05694102 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03045848 0,05689681 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03045848 0,05685267 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03045848 0,0568086 ! activation of innate immune response GO:0002218 12 10 0,000 0,03045848 0,0567646 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03045848 0,05672066 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03045848 0,05667679 ! response to nicotine GO:0035094 20 10 0,000 0,03045848 0,05663299 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03045848 0,05658926 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03045848 0,0565456 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03045848 0,056502 ! localization within membrane GO:0051668 20 10 0,000 0,03045848 0,05645847 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03105063 0,0575118 ! ossification GO:0001503 188 90 1,000 0,03169365 0,05865764 ! bone development GO:0060348 189 91 1,000 0,03234193 0,05981144 ! response to protein stimulus GO:0051789 149 91 1,000 0,03234193 0,0597655 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03345337 0,06177192 ! respiratory burst GO:0045730 17 11 0,000 0,03345337 0,06172455 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03345337 0,06167725 ! neuron fate specification GO:0048665 17 11 0,000 0,03345337 0,06163003 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03345337 0,06158287 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03345337 0,06153579 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03345337 0,06148878 ! thyroid gland development GO:0030878 26 11 0,000 0,03345337 0,06144184 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,03345337 0,06139498 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03345337 0,06134818 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03345337 0,06130146 ! response to pain GO:0048265 24 11 0,000 0,03345337 0,06125481 ! T cell proliferation GO:0042098 26 11 0,000 0,03345337 0,06120822 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03345337 0,06116171 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03345337 0,06111527 ! bone resorption GO:0045453 16 11 0,000 0,03345337 0,0610689 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03345337 0,0610226 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03345337 0,06097637 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03345337 0,06093022 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03345337 0,06088413 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03345337 0,06083811 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03345337 0,06079216 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03345337 0,06074628 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03345337 0,06070046 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03345337 0,06065472 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03345337 0,06060905 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03345337 0,06056344 ! UV protection GO:0009650 19 11 0,000 0,03345337 0,06051791 ! adult heart development GO:0007512 14 11 0,000 0,03345337 0,06047244 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03345337 0,06042704 ! temperature homeostasis GO:0001659 17 11 0,000 0,03345337 0,06038171 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03345337 0,06033644 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03345337 0,06029125 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03345337 0,06024612 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03345337 0,06020106 ! regulation of organ growth GO:0046620 13 11 0,000 0,03345337 0,06015606 ! pigment granule localization GO:0051875 20 11 0,000 0,03345337 0,06011114 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03345337 0,06006628 ! vasoconstriction GO:0042310 18 11 0,000 0,03345337 0,06002149 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03345337 0,05997676 ! embryonic axis specification GO:0000578 18 11 0,000 0,03345337 0,0599321 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03345337 0,05988751 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03345337 0,05984298 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03345337 0,05979853 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03345337 0,05975413 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03345337 0,0597098 ! zymogen activation GO:0031638 15 11 0,000 0,03345337 0,05966554 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03345337 0,05962134 ! nucleosome positioning GO:0016584 15 11 0,000 0,03345337 0,05957721 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03345337 0,05953315 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03345337 0,05948915 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03345337 0,05944521 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03345337 0,05940134 ! acid secretion GO:0046717 18 11 0,000 0,03345337 0,05935753 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03345337 0,05931379 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03345337 0,05927011 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03345337 0,0592265 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03345337 0,05918295 ! oocyte differentiation GO:0009994 18 11 0,000 0,03345337 0,05913947 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03345337 0,05909605 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03345337 0,05905269 ! cholesterol efflux GO:0033344 19 11 0,000 0,03345337 0,05900939 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03345337 0,05896616 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03345337 0,058923 ! germ cell migration GO:0008354 25 11 0,000 0,03345337 0,05887989 ! embryonic gut development GO:0048566 15 11 0,000 0,03345337 0,05883685 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03345337 0,05879387 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03345337 0,05875096 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03345337 0,05870811 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03345337 0,05866532 ! defense response to fungus GO:0050832 13 11 0,000 0,03345337 0,05862259 ! developmental induction GO:0031128 19 11 0,000 0,03345337 0,05857992 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03345337 0,05853732 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03345337 0,05849478 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03345337 0,0584523 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03345337 0,05840988 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03345337 0,05836752 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03345337 0,05832523 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03365409 0,05863268 ! female pregnancy GO:0007565 164 94 1,000 0,0343179 0,05974592 ! transcription initiation GO:0006352 153 94 1,000 0,0343179 0,05970272 ! forebrain development GO:0030900 188 95 1,000 0,03498681 0,06082245 ! positive regulation of immune response GO:0050778 156 96 1,000 0,0356608 0,06194937 ! protein ubiquitination GO:0016567 217 97 1,000 0,03633981 0,06308339 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03643912 0,06321018 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03643912 0,06316464 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03643912 0,06311916 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03643912 0,06307375 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03643912 0,06302841 ! cartilage condensation GO:0001502 20 12 0,000 0,03643912 0,06298313 ! mating GO:0007618 17 12 0,000 0,03643912 0,06293792 ! protein complex disassembly GO:0043241 27 12 0,000 0,03643912 0,06289277 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03643912 0,06284768 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03643912 0,06280266 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03643912 0,06275771 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03643912 0,06271282 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03643912 0,06266799 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03643912 0,06262323 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03643912 0,06257853 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03643912 0,06253389 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03643912 0,06248932 ! drug transport GO:0015893 16 12 0,000 0,03643912 0,06244481 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03643912 0,06240037 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03643912 0,06235599 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03643912 0,06231167 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03643912 0,06226741 ! focal adhesion formation GO:0048041 35 12 0,000 0,03643912 0,06222322 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03643912 0,06217909 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03643912 0,06213502 ! forebrain cell migration GO:0021885 21 12 0,000 0,03643912 0,06209102 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03643912 0,06204707 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03643912 0,06200319 ! fear response GO:0042596 26 12 0,000 0,03643912 0,06195938 ! monoamine transport GO:0015844 18 12 0,000 0,03643912 0,06191562 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03643912 0,06187192 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03643912 0,06182829 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03643912 0,06178472 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03643912 0,06174121 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03643912 0,06169776 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03643912 0,06165437 ! protein homotetramerization GO:0051289 21 12 0,000 0,03643912 0,06161104 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03643912 0,06156778 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03643912 0,06152457 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03643912 0,06148143 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03643912 0,06143834 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03643912 0,06139532 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03643912 0,06135236 ! cranial nerve development GO:0021545 20 12 0,000 0,03643912 0,06130945 ! fucose catabolic process GO:0019317 22 12 0,000 0,03643912 0,06126661 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03643912 0,06122382 ! histone acetylation GO:0016573 26 12 0,000 0,03643912 0,0611811 ! histone methylation GO:0016571 26 12 0,000 0,03643912 0,06113844 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03643912 0,06109583 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03643912 0,06105328 ! gland morphogenesis GO:0022612 29 12 0,000 0,03643912 0,0610108 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03643912 0,06096837 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03643912 0,060926 ! T cell homeostasis GO:0043029 25 12 0,000 0,03643912 0,06088369 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03643912 0,06084144 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03643912 0,06079925 ! spleen development GO:0048536 22 12 0,000 0,03643912 0,06075712 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03643912 0,06071504 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03643912 0,06067302 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03643912 0,06063106 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03643912 0,06058916 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03643912 0,06054732 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03643912 0,06050553 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03643912 0,0604638 ! response to cold GO:0009409 17 12 0,000 0,03643912 0,06042213 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03643912 0,06038052 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03643912 0,06033897 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,03702381 0,06126499 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03771278 0,06236216 GO:0060538|skeletal muscle organ development, ! cGMP metabolic process GO:0046068 18 13 0,000 0,03941574 0,06513342 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03941574 0,06508872 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03941574 0,06504408 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03941574 0,0649995 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03941574 0,06495498 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03941574 0,06491052 ! lipid localization GO:0010876 28 13 0,000 0,03941574 0,06486612 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03941574 0,06482178 ! organelle fusion GO:0048284 32 13 0,000 0,03941574 0,0647775 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03941574 0,06473329 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03941574 0,06468913 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03941574 0,06464503 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03941574 0,064601 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03941574 0,06455702 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03941574 0,06451311 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03941574 0,06446925 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03941574 0,06442545 ! methionine metabolic process GO:0006555 27 13 0,000 0,03941574 0,06438171 ! plasma membrane organization GO:0007009 24 13 0,000 0,03941574 0,06433804 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03941574 0,06429442 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03941574 0,06425086 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03941574 0,06420736 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03941574 0,06416391 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03941574 0,06412053 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03941574 0,06407721 ! exocrine system development GO:0035272 32 13 0,000 0,03941574 0,06403394 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03941574 0,06399073 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03941574 0,06394758 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03941574 0,06390449 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03941574 0,06386146 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03941574 0,06381848 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03941574 0,06377557 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03941574 0,06373271 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03941574 0,0636899 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03941574 0,06364716 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03941574 0,06360447 ! ribosome assembly GO:0042255 17 13 0,000 0,03941574 0,06356184 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,03941574 0,06351927 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03941574 0,06347675 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03941574 0,06343429 ! chromatin silencing GO:0006342 26 13 0,000 0,03941574 0,06339189 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03941574 0,06334954 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03941574 0,06330725 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03941574 0,06326502 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03941574 0,06322284 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03941574 0,06318072 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03941574 0,06313866 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03941574 0,06309665 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03941574 0,0630547 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03941574 0,0630128 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03941574 0,06297096 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03941574 0,06292917 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03941574 0,06288744 ! insulin secretion GO:0030073 23 13 0,000 0,03941574 0,06284577 ! actin filament polymerization GO:0030041 24 13 0,000 0,03941574 0,06280415 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03941574 0,06276259 ! acrosome reaction GO:0007340 18 13 0,000 0,03941574 0,06272108 ! rRNA transcription GO:0009303 25 14 0,000 0,04238326 0,06739863 ! lactation GO:0007595 26 14 0,000 0,04238326 0,06735411 ! reproductive cellular process GO:0048610 20 14 0,000 0,04238326 0,06730966 ! tRNA modification GO:0006400 20 14 0,000 0,04238326 0,06726526 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04238326 0,06722092 ! regulation of S phase GO:0033261 23 14 0,000 0,04238326 0,06717663 ! water transport GO:0006833 21 14 0,000 0,04238326 0,06713241 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04238326 0,06708824 ! non-recombinational repair GO:0000726 25 14 0,000 0,04238326 0,06704413 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04238326 0,06700008 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04238326 0,06695609 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04238326 0,06691216 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04238326 0,06686828 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04238326 0,06682446 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04238326 0,0667807 ! palate development GO:0060021 31 14 0,000 0,04238326 0,06673699 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04238326 0,06669335 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04238326 0,06664976 ! arginine metabolic process GO:0006525 17 14 0,000 0,04238326 0,06660622 ! regulation of heart rate GO:0002027 24 14 0,000 0,04238326 0,06656275 ! organic alcohol transport GO:0015850 29 14 0,000 0,04238326 0,06651933 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04238326 0,06647596 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04238326 0,06643266 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04238326 0,06638941 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04238326 0,06634621 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04238326 0,06630307 ! L-amino acid transport GO:0015807 30 14 0,000 0,04238326 0,06625999 ! bone mineralization GO:0030282 17 14 0,000 0,04238326 0,06621697 ! stem cell development GO:0048864 43 14 0,000 0,04238326 0,066174 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04238326 0,06613108 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04238326 0,06608822 ! cerebellum development GO:0021549 21 14 0,000 0,04238326 0,06604542 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04238326 0,06600267 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04238326 0,06595998 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04238326 0,06591734 ! cofactor transport GO:0051181 26 14 0,000 0,04238326 0,06587476 ! NADP metabolic process GO:0006739 24 14 0,000 0,04238326 0,06583223 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04238326 0,06578976 ! intestinal absorption GO:0050892 25 14 0,000 0,04238326 0,06574734 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04238326 0,06570498 ! oxygen transport GO:0015671 21 14 0,000 0,04238326 0,06566267 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04238326 0,06562042 ! male genitalia development GO:0030539 24 14 0,000 0,04238326 0,06557822 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04238326 0,06553607 ! regulation of axon extension GO:0030516 37 14 0,000 0,04238326 0,06549398 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04238326 0,06545194 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04534172 0,06997573 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04534172 0,06993088 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04534172 0,06988608 ! superoxide anion generation GO:0042554 20 15 0,000 0,04534172 0,06984134 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04534172 0,06979665 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04534172 0,06975203 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04534172 0,06970746 ! copper ion transport GO:0006825 20 15 0,000 0,04534172 0,06966294 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04534172 0,06961849 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04534172 0,06957409 ! sulfate transport GO:0008272 23 15 0,000 0,04534172 0,06952974 ! response to cAMP GO:0051591 22 15 0,000 0,04534172 0,06948546 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04534172 0,06944123 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04534172 0,06939705 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04534172 0,06935294 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04534172 0,06930888 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04534172 0,06926487 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04534172 0,06922092 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04534172 0,06917703 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04534172 0,06913319 ! pituitary gland development GO:0021983 29 15 0,000 0,04534172 0,0690894 ! vesicle coating GO:0006901 33 15 0,000 0,04534172 0,06904568 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04534172 0,069002 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04534172 0,06895839 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04534172 0,06891483 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04534172 0,06887132 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04534172 0,06882787 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04534172 0,06878447 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04534172 0,06874113 ! histone deacetylation GO:0016575 20 15 0,000 0,04534172 0,06869784 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04534172 0,06865461 ! tissue regeneration GO:0042246 26 15 0,000 0,04534172 0,06861143 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04534172 0,0685683 ! water homeostasis GO:0030104 27 15 0,000 0,04534172 0,06852523 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04534172 0,06848222 ! muscle maintenance GO:0046716 26 15 0,000 0,04534172 0,06843925 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04534172 0,06839634 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04534172 0,06835349 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04534172 0,06831069 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04534172 0,06826794 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04534172 0,06822525 ! cell killing GO:0001906 29 15 0,000 0,04534172 0,06818261 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04534172 0,06814002 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04534172 0,06809748 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04534172 0,068055 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04534172 0,06801257 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04534172 0,0679702 ! peptide hormone processing GO:0016486 23 15 0,000 0,04534172 0,06792788 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04829113 0,07230147 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04829113 0,0722565 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04829113 0,0722116 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04829113 0,07216674 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04829113 0,07212195 ! bone remodeling GO:0046849 27 16 0,000 0,04829113 0,07207721 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04829113 0,07203252 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04829113 0,07198789 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04829113 0,07194332 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04829113 0,0718988 ! startle response GO:0001964 28 16 0,000 0,04829113 0,07185433 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04829113 0,07180992 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04829113 0,07176557 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04829113 0,07172127 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04829113 0,07167702 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04829113 0,07163283 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04829113 0,0715887 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04829113 0,07154462 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04829113 0,07150059 ! response to osmotic stress GO:0006970 25 16 0,000 0,04829113 0,07145662 ! lysosomal transport GO:0007041 26 16 0,000 0,04829113 0,0714127 ! fructose metabolic process GO:0006000 25 16 0,000 0,04829113 0,07136883 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04829113 0,07132502 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04829113 0,07128126 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04829113 0,07123756 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04829113 0,07119391 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04829113 0,07115031 ! axon cargo transport GO:0008088 43 16 0,000 0,04829113 0,07110677 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04829113 0,07106328 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04829113 0,07101984 ! DNA replication initiation GO:0006270 27 16 0,000 0,04829113 0,07097645 ! neuron recognition GO:0008038 35 16 0,000 0,04829113 0,07093312 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04829113 0,07088985 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04829113 0,07084662 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04829113 0,07080345 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04829113 0,07076033 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04829113 0,07071726 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04829113 0,07067424 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04829113 0,07063128 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04829113 0,07058837 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04829113 0,07054551 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04829113 0,0705027 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04829113 0,07045995 ! defense response to virus GO:0051607 37 16 0,000 0,04829113 0,07041725 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05123153 0,07465963 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05123153 0,07461444 ! metencephalon development GO:0022037 30 17 0,000 0,05123153 0,0745693 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05123153 0,07452422 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05123153 0,07447919 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05123153 0,07443421 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05123153 0,07438929 ! signal complex assembly GO:0007172 41 17 0,000 0,05123153 0,07434442 ! endothelial cell migration GO:0043542 28 17 0,000 0,05123153 0,07429961 ! inositol metabolic process GO:0006020 28 17 0,000 0,05123153 0,07425485 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05123153 0,07421015 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05123153 0,0741655 ! glial cell development GO:0021782 27 17 0,000 0,05123153 0,0741209 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05123153 0,07407636 ! adult walking behavior GO:0007628 33 17 0,000 0,05123153 0,07403186 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05123153 0,07398743 ! heart looping GO:0001947 30 17 0,000 0,05123153 0,07394304 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05123153 0,07389871 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05123153 0,07385444 ! myoblast differentiation GO:0045445 45 17 0,000 0,05123153 0,07381021 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05123153 0,07376604 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05123153 0,07372192 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05123153 0,07367786 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05123153 0,07363384 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05123153 0,07358988 ! NAD metabolic process GO:0019674 29 17 0,000 0,05123153 0,07354598 ! membrane budding GO:0006900 37 17 0,000 0,05123153 0,07350212 ! DNA integration GO:0015074 29 17 0,000 0,05123153 0,07345832 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05123153 0,07341457 ! regulation of protein binding GO:0043393 33 17 0,000 0,05123153 0,07337087 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05123153 0,07332722 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05123153 0,07328362 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05123153 0,07324008 ! genitalia development GO:0048806 30 17 0,000 0,05123153 0,07319659 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05123153 0,07315315 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05123153 0,07310976 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05123153 0,07306642 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05123153 0,07302314 ! steroid catabolic process GO:0006706 31 17 0,000 0,05123153 0,0729799 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05123153 0,07293672 ! gas transport GO:0015669 25 17 0,000 0,05123153 0,07289359 ! organic cation transport GO:0015695 31 17 0,000 0,05123153 0,07285051 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05123153 0,07280747 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05123153 0,0727645 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05123153 0,07272157 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05123153 0,07267869 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05416294 0,076792 ! neuron maturation GO:0042551 42 18 0,000 0,05416294 0,07674678 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05416294 0,07670161 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05416294 0,07665649 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05416294 0,07661142 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05416294 0,07656641 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05416294 0,07652145 ! memory GO:0007613 31 18 0,000 0,05416294 0,07647654 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05416294 0,07643169 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05416294 0,07638689 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05416294 0,07634214 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05416294 0,07629744 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05416294 0,0762528 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05416294 0,0762082 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05416294 0,07616366 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05416294 0,07611918 ! response to retinoic acid GO:0032526 26 18 0,000 0,05416294 0,07607474 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05416294 0,07603036 ! response to fungus GO:0009620 21 18 0,000 0,05416294 0,07598602 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05416294 0,07594174 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05416294 0,07589751 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05416294 0,07585333 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05416294 0,07580921 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05416294 0,07576513 ! vitamin transport GO:0051180 27 18 0,000 0,05416294 0,07572111 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05416294 0,07567714 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05416294 0,07563321 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05416294 0,07558934 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05416294 0,07554552 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05416294 0,07550176 ! nerve development GO:0021675 28 18 0,000 0,05416294 0,07545804 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05416294 0,07541437 ! protein secretion GO:0009306 39 19 0,000 0,05708539 0,0794375 ! positive regulation of translation GO:0045727 30 19 0,000 0,05708539 0,07939159 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05708539 0,07934572 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05708539 0,07929991 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05708539 0,07925415 ! skin development GO:0043588 36 19 0,000 0,05708539 0,07920845 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05708539 0,07916279 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05708539 0,07911719 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05708539 0,07907164 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05708539 0,07902615 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05708539 0,07898071 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05708539 0,07893531 ! cerebral cortex development GO:0021987 36 19 0,000 0,05708539 0,07888997 ! response to vitamin A GO:0033189 27 19 0,000 0,05708539 0,07884469 ! heme metabolic process GO:0042168 36 19 0,000 0,05708539 0,07879945 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05708539 0,07875427 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05708539 0,07870914 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05708539 0,07866406 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05708539 0,07861903 ! peptide cross-linking GO:0018149 37 19 0,000 0,05708539 0,07857405 ! protein export from nucleus GO:0006611 36 19 0,000 0,05708539 0,07852913 ! heart process GO:0003015 30 19 0,000 0,05708539 0,07848425 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05708539 0,07843943 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05708539 0,07839466 ! visual learning GO:0008542 36 19 0,000 0,05708539 0,07834994 ! G1 phase GO:0051318 40 19 0,000 0,05708539 0,07830527 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05708539 0,07826065 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05708539 0,07821609 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05708539 0,07817157 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05708539 0,0781271 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05708539 0,07808269 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05708539 0,07803832 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05708539 0,07799401 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05708539 0,07794974 ! cilium assembly GO:0042384 37 19 0,000 0,05708539 0,07790553 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05708539 0,07786136 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05999891 0,08178888 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05999891 0,08174257 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05999891 0,0816963 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05999891 0,0816501 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05999891 0,08160394 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,05999891 0,08155784 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05999891 0,08151178 ! response to vitamin GO:0033273 31 20 0,000 0,05999891 0,08146578 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05999891 0,08141984 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05999891 0,08137394 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05999891 0,0813281 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05999891 0,0812823 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05999891 0,08123656 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05999891 0,08119087 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05999891 0,08114523 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05999891 0,08109965 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05999891 0,08105411 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05999891 0,08100863 ! body fluid secretion GO:0007589 31 20 0,000 0,05999891 0,08096319 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05999891 0,08091781 ! peptide secretion GO:0002790 35 20 0,000 0,05999891 0,08087248 ! stem cell differentiation GO:0048863 53 20 0,000 0,05999891 0,08082719 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05999891 0,08078196 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05999891 0,08073678 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05999891 0,08069165 ! sensory perception of pain GO:0019233 30 20 0,000 0,05999891 0,08064658 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05999891 0,08060155 ! diencephalon development GO:0021536 34 20 0,000 0,05999891 0,08055657 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05999891 0,08051164 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05999891 0,08046676 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05999891 0,08042193 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05999891 0,08037715 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05999891 0,08033243 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05999891 0,08028775 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05999891 0,08024312 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05999891 0,08019854 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05999891 0,08015401 ! actin filament-based movement GO:0030048 43 20 0,000 0,05999891 0,08010953 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05999891 0,0800651 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05999891 0,08002071 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05999891 0,07997638 ! regulation of cell killing GO:0031341 42 21 0,000 0,06290352 0,0838017 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06290352 0,08375532 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06290352 0,083709 ! hormone secretion GO:0046879 38 21 0,000 0,06290352 0,08366272 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06290352 0,0836165 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06290352 0,08357033 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06290352 0,08352421 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06290352 0,08347814 ! axis specification GO:0009798 38 21 0,000 0,06290352 0,08343212 ! ovarian follicle development GO:0001541 35 21 0,000 0,06290352 0,08338615 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06290352 0,08334023 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06290352 0,08329437 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06290352 0,08324855 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06290352 0,08320278 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06290352 0,08315707 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06290352 0,0831114 ! cytolysis GO:0019835 24 21 0,000 0,06290352 0,08306579 ! vasodilation GO:0042311 39 21 0,000 0,06290352 0,08302022 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06290352 0,08297471 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06290352 0,08292924 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06290352 0,08288383 ! oogenesis GO:0048477 36 21 0,000 0,06290352 0,08283846 ! collagen fibril organization GO:0030199 59 21 0,000 0,06290352 0,08279314 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06290352 0,08274788 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06290352 0,08270266 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06290352 0,08265749 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06290352 0,08261237 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06290352 0,0825673 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06290352 0,08252228 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06290352 0,08247731 ! gut development GO:0048565 39 21 0,000 0,06290352 0,08243239 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06579925 0,08618018 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06579925 0,0861333 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06579925 0,08608646 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06579925 0,08603967 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06579925 0,08599294 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06579925 0,08594625 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06579925 0,08589962 ! regeneration GO:0031099 41 22 0,000 0,06579925 0,08585304 ! keratinization GO:0031424 28 22 0,000 0,06579925 0,0858065 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06579925 0,08576002 ! sensory perception of taste GO:0050909 28 22 0,000 0,06579925 0,08571359 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06579925 0,08566721 ! vacuolar transport GO:0007034 36 22 0,000 0,06579925 0,08562088 ! lysosome organization GO:0007040 41 22 0,000 0,06579925 0,08557459 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06579925 0,08552836 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06579925 0,08548218 ! fucose metabolic process GO:0006004 39 22 0,000 0,06579925 0,08543605 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06579925 0,08538997 ! ureteric bud development GO:0001657 43 22 0,000 0,06579925 0,08534393 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06579925 0,08529795 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06579925 0,08525202 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06579925 0,08520614 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06579925 0,0851603 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06579925 0,08511452 ! sarcomere organization GO:0045214 30 22 0,000 0,06579925 0,08506878 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,06579925 0,08502309 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06579925 0,08497746 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06579925 0,08493187 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06579925 0,08488633 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06579925 0,08484084 ! protein stabilization GO:0050821 39 22 0,000 0,06579925 0,08479539 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06868613 0,08846833 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06868613 0,08842099 ! gluconeogenesis GO:0006094 33 23 0,000 0,06868613 0,08837371 ! viral genome replication GO:0019079 41 23 0,000 0,06868613 0,08832647 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06868613 0,08827929 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06868613 0,08823216 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06868613 0,08818508 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06868613 0,08813804 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06868613 0,08809106 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06868613 0,08804413 ! visual behavior GO:0007632 42 23 0,000 0,06868613 0,08799725 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06868613 0,08795042 ! response to ethanol GO:0045471 46 23 0,000 0,06868613 0,08790363 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06868613 0,0878569 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,06868613 0,08781022 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06868613 0,08776359 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06868613 0,087717 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06868613 0,08767047 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06868613 0,08762398 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06868613 0,08757755 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06868613 0,08753116 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06868613 0,08748482 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06868613 0,08743854 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06868613 0,0873923 ! fatty acid transport GO:0015908 44 23 0,000 0,06868613 0,08734611 ! platelet activation GO:0030168 37 23 0,000 0,06868613 0,08729996 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06868613 0,08725387 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06868613 0,08720783 ! hormone transport GO:0009914 40 23 0,000 0,06868613 0,08716183 ! cell-cell recognition GO:0009988 25 23 0,000 0,06868613 0,08711588 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06868613 0,08706999 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06868613 0,08702414 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06868613 0,08697833 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06868613 0,08693258 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06868613 0,08688687 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,07156419 0,09048 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07156419 0,09043248 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07156419 0,090385 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07156419 0,09033758 ! vesicle docking GO:0048278 47 24 0,000 0,07156419 0,09029021 ! spinal cord development GO:0021510 47 24 0,000 0,07156419 0,09024289 ! vacuole organization GO:0007033 43 24 0,000 0,07156419 0,09019562 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07156419 0,09014839 ! digestive system process GO:0022600 39 24 0,000 0,07156419 0,09010122 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07156419 0,0900541 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07156419 0,09000702 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07156419 0,08996 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07156419 0,08991302 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07156419 0,08986609 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07156419 0,08981921 ! membrane depolarization GO:0051899 39 24 0,000 0,07156419 0,08977238 ! pentose metabolic process GO:0019321 35 24 0,000 0,07156419 0,0897256 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,07156419 0,08967887 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07156419 0,08963219 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07156419 0,08958555 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07156419 0,08953897 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07156419 0,08949243 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07156419 0,08944594 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07156419 0,0893995 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07156419 0,08935311 ! regulation of amine transport GO:0051952 40 24 0,000 0,07156419 0,08930676 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07443344 0,09283922 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,07443344 0,09279112 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07443344 0,09274307 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07443344 0,09269506 ! phototransduction GO:0007602 33 25 0,000 0,07443344 0,09264711 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07443344 0,09259921 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07443344 0,09255135 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07443344 0,09250355 ! receptor metabolic process GO:0043112 46 25 0,000 0,07443344 0,09245579 ! chromosome condensation GO:0030261 45 25 0,000 0,07443344 0,09240808 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07443344 0,09236043 ! neural crest cell development GO:0014032 54 25 0,000 0,07443344 0,09231282 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07443344 0,09226526 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07443344 0,09221775 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07443344 0,09217029 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07443344 0,09212287 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07443344 0,09207551 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07443344 0,09202819 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,07443344 0,09198093 ! immunoglobulin production GO:0002377 55 25 0,000 0,07443344 0,09193371 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07443344 0,09188654 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07443344 0,09183942 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07443344 0,09179234 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07443344 0,09174532 ! neural tube closure GO:0001843 49 25 0,000 0,07443344 0,09169834 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07443344 0,09165141 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07729393 0,09512491 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07729393 0,09507627 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07729393 0,09502769 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07729393 0,09497916 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07729393 0,09493067 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07729393 0,09488224 ! molting cycle process GO:0022404 50 26 0,000 0,07729393 0,09483385 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07729393 0,09478552 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07729393 0,09473723 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07729393 0,094689 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07729393 0,09464081 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07729393 0,09459267 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07729393 0,09454458 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07729393 0,09449654 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07729393 0,09444855 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07729393 0,0944006 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07729393 0,09435271 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07729393 0,09430486 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07729393 0,09425707 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07729393 0,09420932 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07729393 0,09416161 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07729393 0,09411396 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07729393 0,09406636 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07729393 0,0940188 ! neuron fate commitment GO:0048663 48 27 0,000 0,08014567 0,09743834 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08014567 0,09738913 ! iron ion transport GO:0006826 59 27 0,000 0,08014567 0,09733997 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08014567 0,09729085 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08014567 0,09724179 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08014567 0,09719278 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08014567 0,09714381 ! autophagy GO:0006914 41 27 0,000 0,08014567 0,0970949 ! male gonad development GO:0008584 44 27 0,000 0,08014567 0,09704604 ! response to toxin GO:0009636 47 27 0,000 0,08014567 0,09699722 ! primary neural tube formation GO:0014020 51 27 0,000 0,08014567 0,09694845 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08014567 0,09689973 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08014567 0,09685107 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08014567 0,09680245 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08014567 0,09675387 ! circadian rhythm GO:0007623 50 28 0,000 0,08298869 0,1001358 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08298869 0,1000856 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08298869 0,10003546 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08298869 0,09998537 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08298869 0,09993532 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08298869 0,09988533 ! synaptogenesis GO:0007416 42 28 0,000 0,08298869 0,09983539 ! lipid oxidation GO:0034440 43 28 0,000 0,08298869 0,0997855 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08298869 0,09973565 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08298869 0,09968586 ! translational initiation GO:0006413 65 29 0,000 0,08582301 0,10303901 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08582301 0,10298761 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08582301 0,10293627 ! catechol metabolic process GO:0009712 54 29 0,000 0,08582301 0,10288499 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08582301 0,10283375 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08582301 0,10278256 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08582301 0,10273143 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08582301 0,10268034 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08582301 0,10262931 ! cell fate determination GO:0001709 60 29 0,000 0,08582301 0,10257832 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08582301 0,10252739 ! detection of light stimulus GO:0009583 38 29 0,000 0,08582301 0,10247651 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08582301 0,10242568 ! regulation of coagulation GO:0050818 46 29 0,000 0,08582301 0,1023749 ! phenol metabolic process GO:0018958 55 30 0,000 0,08864867 0,10569311 ! zinc ion transport GO:0006829 45 30 0,000 0,08864867 0,10564077 ! membrane docking GO:0022406 61 30 0,000 0,08864867 0,10558847 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08864867 0,10553622 ! cell junction assembly GO:0034329 78 30 0,000 0,08864867 0,10548403 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08864867 0,10543189 ! acute-phase response GO:0006953 49 30 0,000 0,08864867 0,10537979 ! myofibril assembly GO:0030239 47 30 0,000 0,08864867 0,10532776 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08864867 0,10527577 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08864867 0,10522383 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08864867 0,10517195 ! phospholipid transport GO:0015914 51 30 0,000 0,08864867 0,10512011 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08864867 0,10506833 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08864867 0,1050166 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08864867 0,10496491 ! eye morphogenesis GO:0048592 60 30 0,000 0,08864867 0,10491328 ! response to heat GO:0009408 50 30 0,000 0,08864867 0,1048617 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09146569 0,10814076 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09146569 0,10808765 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09146569 0,10803459 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09146569 0,10798158 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09146569 0,10792862 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09146569 0,10787571 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09146569 0,10782286 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09146569 0,10777006 ! ovulation cycle process GO:0022602 49 31 0,000 0,09146569 0,10771731 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09146569 0,10766461 ! peptide transport GO:0015833 55 31 0,000 0,09146569 0,10761196 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09146569 0,10755936 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09146569 0,10750682 ! mesoderm formation GO:0001707 69 31 0,000 0,09146569 0,10745432 ! natural killer cell activation GO:0030101 45 31 0,000 0,09146569 0,10740188 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09146569 0,10734949 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09146569 0,10729715 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09146569 0,10724486 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0942741 0,11048392 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0942741 0,11043013 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0942741 0,11037639 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0942741 0,1103227 ! cholesterol transport GO:0030301 56 32 0,000 0,0942741 0,11026907 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0942741 0,11021549 ! spliceosome assembly GO:0000245 67 32 0,000 0,0942741 0,11016196 ! spindle organization GO:0007051 46 32 0,000 0,0942741 0,11010848 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0942741 0,11005506 ! metanephros development GO:0001656 74 32 0,000 0,0942741 0,11000169 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0942741 0,10994837 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0942741 0,1098951 ! muscle cell development GO:0055001 49 32 0,000 0,0942741 0,10984188 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0942741 0,10978871 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0942741 0,1097356 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0942741 0,10968253 ! ovulation cycle GO:0042698 51 32 0,000 0,0942741 0,10962952 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0942741 0,10957656 ! hindbrain development GO:0030902 61 32 0,000 0,0942741 0,10952365 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0942741 0,10947079 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0942741 0,10941798 ! gene silencing GO:0016458 65 32 0,000 0,0942741 0,10936523 ! post-embryonic development GO:0009791 69 33 0,000 0,09707391 0,11255896 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09707391 0,11250474 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09707391 0,11245057 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09707391 0,11239646 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09707391 0,1123424 ! cell fate specification GO:0001708 52 33 0,000 0,09707391 0,11228838 ! sterol transport GO:0015918 57 33 0,000 0,09707391 0,11223443 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09707391 0,11218052 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09707391 0,11212666 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09707391 0,11207286 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09986517 0,1152401 ! glial cell differentiation GO:0010001 63 34 0,000 0,09986517 0,11518485 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09986517 0,11512966 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09986517 0,11507452 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09986517 0,11501943 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09986517 0,1149644 ! mismatch repair GO:0006298 46 34 0,000 0,09986517 0,11490942 ! spermatid development GO:0007286 63 34 0,000 0,09986517 0,11485449 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09986517 0,11479962 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09986517 0,11474479 ! regulation of muscle development GO:0048634 70 35 0,000 0,10264789 0,11788583 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10264789 0,11782959 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10264789 0,1177734 ! odontogenesis GO:0042476 66 35 0,000 0,10264789 0,11771726 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10264789 0,11766118 ! female gonad development GO:0008585 58 35 0,000 0,10264789 0,11760515 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10264789 0,11754918 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 0,000 0,10264789 0,11749325 ! cytokine production GO:0001816 59 35 0,000 0,10264789 0,11743739 ! neural tube formation GO:0001841 67 35 0,000 0,10264789 0,11738157 ! vesicle localization GO:0051648 64 35 0,000 0,10264789 0,11732581 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1054221 0,12043949 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1054221 0,12038233 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,1054221 0,12032522 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1054221 0,12026817 ! cell junction organization GO:0034330 86 36 0,000 0,1054221 0,12021117 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1054221 0,12015422 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1054221 0,12009733 ! positive regulation of cell development GO:0010720 80 36 0,000 0,1054221 0,1200405 ! regulation of proteolysis GO:0030162 72 36 0,000 0,1054221 0,11998371 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1054221 0,11992698 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1054221 0,11987031 ! aerobic respiration GO:0009060 55 36 0,000 0,1054221 0,11981368 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,1054221 0,11975711 ! embryonic organ development GO:0048568 57 36 0,000 0,1054221 0,1197006 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1054221 0,11964414 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10818782 0,12272508 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10818782 0,12266725 ! meiosis I GO:0007127 65 37 0,000 0,10818782 0,12260947 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10818782 0,12255174 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10818782 0,12249407 ! organic anion transport GO:0015711 68 37 0,000 0,10818782 0,12243645 ! tissue remodeling GO:0048771 76 37 0,000 0,10818782 0,12237889 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10818782 0,12232138 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10818782 0,12226393 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10818782 0,12220653 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,10818782 0,12214918 ! spermatid differentiation GO:0048515 66 37 0,000 0,10818782 0,12209189 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11094509 0,12514481 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11094509 0,12508617 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11094509 0,12502758 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11094509 0,12496904 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,11094509 0,12491057 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11094509 0,12485214 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11094509 0,12479377 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11094509 0,12473546 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11094509 0,1246772 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,11094509 0,12461899 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11094509 0,12456084 ! mRNA catabolic process GO:0006402 71 39 0,000 0,11369392 0,12758749 ! learning GO:0007612 77 39 0,000 0,11369392 0,127528 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11369392 0,12746858 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11369392 0,12740921 ! segmentation GO:0035282 67 39 0,000 0,11369392 0,12734989 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11369392 0,12729063 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11369392 0,12723143 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11369392 0,12717228 ! RNA modification GO:0009451 57 39 0,000 0,11369392 0,12711318 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11369392 0,12705414 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11643434 0,13005619 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11643434 0,12999584 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11643434 0,12993554 ! feeding behavior GO:0007631 59 40 0,000 0,11643434 0,1298753 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11643434 0,12981512 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11643434 0,12975499 ! maintenance of protein location GO:0045185 91 40 0,000 0,11643434 0,12969492 ! cytokinesis GO:0000910 72 40 0,000 0,11643434 0,1296349 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11916638 0,13261532 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11916638 0,13255401 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11916638 0,13249275 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11916638 0,13243156 ! gliogenesis GO:0042063 88 41 0,000 0,11916638 0,13237042 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11916638 0,13230933 ! female gamete generation GO:0007292 61 41 0,000 0,11916638 0,1322483 ! polyol metabolic process GO:0019751 66 41 0,000 0,11916638 0,13218733 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11916638 0,13212641 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,12189007 0,13508406 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 0,000 0,12189007 0,13502187 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12189007 0,13495973 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12189007 0,13489766 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12189007 0,13483563 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12189007 0,13477367 ! neuron migration GO:0001764 79 42 0,000 0,12189007 0,13471176 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12189007 0,13464991 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12460542 0,13758634 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12460542 0,13752323 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12460542 0,13746017 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12460542 0,13739718 ! glucose transport GO:0015758 65 43 0,000 0,12460542 0,13733424 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12460542 0,13727136 ! neural tube development GO:0021915 77 43 0,000 0,12460542 0,13720853 ! striated muscle contraction GO:0006941 77 43 0,000 0,12460542 0,13714576 ! phagocytosis GO:0006909 90 43 0,000 0,12460542 0,13708306 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12460542 0,1370204 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12731247 0,13993321 ! hexose transport GO:0008645 67 44 0,000 0,12731247 0,13986931 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12731247 0,13980547 ! male sex differentiation GO:0046661 76 44 0,000 0,12731247 0,13974169 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12731247 0,13967797 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12731247 0,13961431 ! developmental growth GO:0048589 82 44 0,000 0,12731247 0,1395507 ! maintenance of location in cell GO:0051651 97 44 0,000 0,12731247 0,13948716 ! glycolysis GO:0006096 65 45 0,000 0,13001123 0,14237916 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13001123 0,14231439 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13001123 0,14224967 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13001123 0,14218501 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13001123 0,14212041 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13001123 0,14205587 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13001123 0,14199138 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13001123 0,14192696 ! cell growth GO:0016049 84 45 0,000 0,13001123 0,14186259 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13270174 0,14473272 ! endosome transport GO:0016197 108 47 0,000 0,13538402 0,14759127 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,13538402 0,14752443 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13538402 0,14745765 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13538402 0,14739092 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13538402 0,14732426 ! JNK cascade GO:0007254 91 47 0,000 0,13538402 0,14725766 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13538402 0,14719112 ! protein homooligomerization GO:0051260 76 47 0,000 0,13538402 0,14712463 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13805809 0,14996287 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13805809 0,1498952 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13805809 0,14982758 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13805809 0,14976003 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13805809 0,14969254 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,14072397 0,15251436 ! regulation of ion transport GO:0043269 77 49 0,000 0,14072397 0,15244569 ! peptide metabolic process GO:0006518 76 49 0,000 0,14072397 0,15237708 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14072397 0,15230854 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14072397 0,15224005 ! endocrine system development GO:0035270 104 49 0,000 0,14072397 0,15217163 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14072397 0,15210327 ! neuromuscular process GO:0050905 99 50 0,000 0,14338171 0,15490632 ! regulation of ossification GO:0030278 117 50 0,000 0,14338171 0,1548368 ! inner ear development GO:0048839 79 50 0,000 0,14338171 0,15476733 ! histone modification GO:0016570 91 50 0,000 0,14338171 0,15469793 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14338171 0,15462859 ! positive regulation of binding GO:0051099 78 51 0,000 0,1460313 0,15741547 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,1460313 0,15734497 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1460313 0,15727454 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1460313 0,15720417 ! excretion GO:0007588 83 51 0,000 0,1460313 0,15713386 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1460313 0,15706362 ! chromatin remodeling GO:0006338 109 51 0,000 0,1460313 0,15699344 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1460313 0,15692332 ! vesicle organization GO:0016050 107 51 0,000 0,1460313 0,15685327 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,1460313 0,15678327 ! membrane fusion GO:0006944 110 52 0,000 0,1486728 0,15954806 ! covalent chromatin modification GO:0016569 101 52 0,000 0,1486728 0,15947693 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1486728 0,15940586 ! amino acid activation GO:0043038 92 52 0,000 0,1486728 0,15933485 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1513062 0,16208492 ! RNA catabolic process GO:0006401 93 53 0,000 0,1513062 0,16201279 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1513062 0,16194072 ! cell maturation GO:0048469 100 53 0,000 0,1513062 0,16186871 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,15393155 0,16460414 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15393155 0,16453102 ! cell recognition GO:0008037 85 54 0,000 0,15393155 0,16445796 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15393155 0,16438496 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15393155 0,16431203 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15393155 0,16423917 ! chloride transport GO:0006821 90 55 0,000 0,15654887 0,1669577 ! glucose catabolic process GO:0006007 82 55 0,000 0,15654887 0,16688373 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15654887 0,16680982 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,15654887 0,16673598 ! gastrulation GO:0007369 112 55 0,000 0,15654887 0,1666622 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,15654887 0,16658849 ! RNA elongation GO:0006354 79 55 0,000 0,15654887 0,16651485 ! nuclear export GO:0051168 97 55 0,000 0,15654887 0,16644126 ! sensory perception of smell GO:0007608 80 56 0,000 0,15915818 0,16914071 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,15915818 0,16906604 ! proton transport GO:0015992 94 56 0,000 0,15915818 0,16899143 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,15915818 0,16891688 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,1617595 0,17160201 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,1617595 0,17152638 ! maintenance of location GO:0051235 118 57 0,000 0,1617595 0,17145081 ! hydrogen transport GO:0006818 97 58 0,000 0,16435286 0,17412284 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,16435286 0,1740462 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16435286 0,17396963 ! adult behavior GO:0030534 99 58 0,000 0,16435286 0,17389313 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,16435286 0,17381669 ! positive regulation of secretion GO:0051047 95 59 0,000 0,16693828 0,17647342 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16693828 0,17639591 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16951579 0,17904082 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,16951579 0,17896226 ! camera-type eye development GO:0043010 116 60 0,000 0,16951579 0,17888376 ! kidney development GO:0001822 122 60 0,000 0,16951579 0,17880534 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1720854 0,18143623 ! mesoderm development GO:0007498 119 61 0,000 0,1720854 0,18135676 ! tRNA processing GO:0008033 89 61 0,000 0,1720854 0,18127736 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1720854 0,18119802 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17464716 0,18381499 ! gonad development GO:0008406 98 62 0,000 0,17464716 0,18373461 ! regulation of mitosis GO:0007088 105 63 0,000 0,17720107 0,18633994 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,17720107 0,18625853 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,17720107 0,18617719 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17974716 0,18876983 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17974716 0,18868747 ! single fertilization GO:0007338 75 64 0,000 0,17974716 0,18860518 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18228546 0,19118519 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18228546 0,19110188 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18228546 0,19101865 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,18228546 0,19093549 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18481599 0,19350186 ! actin filament organization GO:0007015 148 66 0,000 0,18481599 0,19341769 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18481599 0,1933336 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18481599 0,19324958 ! secondary metabolic process GO:0019748 116 66 0,000 0,18481599 0,19316563 ! developmental maturation GO:0021700 116 66 0,000 0,18481599 0,19308175 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18733877 0,19563242 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18733877 0,19554754 ! lung development GO:0030324 144 67 0,000 0,18733877 0,19546274 ! chromosome segregation GO:0007059 113 67 0,000 0,18733877 0,19537802 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18733877 0,19529337 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18733877 0,19520879 ! hexose catabolic process GO:0019320 104 67 0,000 0,18733877 0,19512428 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18733877 0,19503985 ! amino acid transport GO:0006865 125 68 0,000 0,18985383 0,1975728 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18985383 0,19748738 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,18985383 0,19740204 ! regulation of lipase activity GO:0060191 130 68 0,000 0,18985383 0,19731677 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18985383 0,19723157 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19236119 0,19975012 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19236119 0,19966394 ! urogenital system development GO:0001655 137 69 0,000 0,19236119 0,19957784 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19236119 0,19949182 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19236119 0,19940587 ! appendage morphogenesis GO:0035107 135 70 0,000 0,19486087 0,2019101 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,19486087 0,20182318 ! reproductive structure development GO:0048608 113 71 0,000 0,1973529 0,20431629 ! appendage development GO:0048736 136 71 0,000 0,1973529 0,20422842 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,1973529 0,20414061 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1973529 0,20405289 ! carbohydrate transport GO:0008643 110 72 0,000 0,19983729 0,20653287 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19983729 0,20644419 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19983729 0,20635559 ! respiratory system development GO:0060541 153 72 0,000 0,19983729 0,20626706 ! learning or memory GO:0007611 147 73 0,000 0,20231408 0,208734 ! regulation of blood pressure GO:0008217 125 73 0,000 0,20231408 0,20864453 ! fertilization GO:0009566 90 73 0,000 0,20231408 0,20855513 ! transition metal ion transport GO:0000041 126 74 0,000 0,20478329 0,2110101 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20478329 0,21091977 ! meiosis GO:0007126 121 74 0,000 0,20478329 0,21082952 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,20478329 0,21073935 ! eye development GO:0001654 143 74 0,000 0,20478329 0,21064925 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20724493 0,2130903 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20724493 0,21299928 ! meiotic cell cycle GO:0051321 122 75 0,000 0,20724493 0,21290833 ! rhythmic process GO:0048511 128 75 0,000 0,20724493 0,21281746 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,20969904 0,21524568 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,20969904 0,21515389 ! defense response to bacterium GO:0042742 89 76 0,000 0,20969904 0,21506218 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,20969904 0,21497055 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21214562 0,21738602 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,21214562 0,21729348 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,21214562 0,21720101 ! blood coagulation GO:0007596 146 78 0,000 0,21458472 0,21960478 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21458472 0,21951141 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,21458472 0,21941812 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21701635 0,22181025 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,21701635 0,22171606 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,21944053 0,22409758 ! muscle cell differentiation GO:0042692 159 80 0,000 0,21944053 0,22400251 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,21944053 0,22390751 ! inorganic anion transport GO:0015698 138 80 0,000 0,21944053 0,22381259 ! response to hypoxia GO:0001666 171 81 0,000 0,22185728 0,22618162 ! digestion GO:0007586 112 81 0,000 0,22185728 0,22608582 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,22185728 0,2259901 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,22426663 0,22834766 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,22426663 0,22825106 ! response to nutrient GO:0007584 125 82 0,000 0,22426663 0,22815455 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,22426663 0,22805812 ! response to oxygen levels GO:0070482 176 83 0,000 0,2266686 0,23040332 ! regulation of lyase activity GO:0051339 160 83 0,000 0,2266686 0,23030602 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,22906322 0,23264082 ! hemostasis GO:0007599 158 84 0,000 0,22906322 0,23254266 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,22906322 0,23244458 ! nucleosome assembly GO:0006334 122 85 0,000 0,23145049 0,23476808 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,23145049 0,23466915 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,23383046 0,23698234 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,23383046 0,23688256 ! chromatin assembly GO:0031497 124 86 0,000 0,23383046 0,23678286 ! tube morphogenesis GO:0035239 176 86 0,000 0,23383046 0,23668325 ! alcohol catabolic process GO:0046164 130 86 0,000 0,23383046 0,23658372 ! amine transport GO:0015837 155 86 0,000 0,23383046 0,23648427 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,23620313 0,2387835 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,23856854 0,24107346 ! regulation of neurological system process GO:0031644 148 88 0,000 0,23856854 0,24097225 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,23856854 0,24087113 ! cellular defense response GO:0006968 114 89 0,000 0,2409267 0,24315001 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,24327763 0,2454197 ! sex differentiation GO:0007548 145 90 0,000 0,24327763 0,24531684 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,24327763 0,24521407 ! sterol metabolic process GO:0016125 152 91 0,000 0,24562136 0,24747278 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,24562136 0,24736919 ! nucleosome organization GO:0034728 138 92 0,000 0,24795791 0,24961788 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,24795791 0,24951348 ! vitamin metabolic process GO:0006766 139 92 0,000 0,24795791 0,24940917 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2502873 0,25164699 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,2502873 0,25154187 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,2502873 0,25143684 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,2502873 0,2513319 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,25260955 0,25355802 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,25492468 0,25577514 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25723272 0,2579833 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,25723272 0,25787581 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,25953369 0,26007416 ! hormone metabolic process GO:0042445 157 97 0,000 0,25953369 0,25996589 ! response to virus GO:0009615 160 98 0,000 0,26182761 0,26215448 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,26182761 0,26204544 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,26411449 0,26422431 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,26411449 0,26411449